1	Decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	12	_	NUM	_	NumType=Card	_	_	_	_
5	production	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	development	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	acetyl	_	ADJ	_	Number=Sing	_	_	_	_
12	salicylic	_	ADJ	_	Degree=Pos	_	_	_	_
13	acid	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
16	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	12	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	75	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kDa	_	NOUN	_	Number=Sing	_	_	_	_
9	heterodimeric	_	ADJ	_	Degree=Pos	_	_	_	_
10	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
11	composed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	two	_	NUM	_	NumType=Card	_	_	_	_
14	covalently	_	ADV	_	_	_	_	_	_
15	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	p35	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	p40	_	NUM	_	Number=Sing	_	_	_	_
19	chains	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	pro-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
4	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	prominent	_	ADJ	_	Degree=Pos	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	development	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
16	immune	_	NOUN	_	Number=Sing	_	_	_	_
17	responses	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
5	immune	_	NOUN	_	Number=Sing	_	_	_	_
6	responses	_	NOUN	_	Number=Plur	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
9	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
15	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	autoimmune	_	NOUN	_	Number=Sing	_	_	_	_
17	diseases	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	12	_	NUM	_	NumType=Card	_	_	_	_
6	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	critical	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	generation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	maintenance	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
19	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
20	conditions	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	effects	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	commonly	_	ADV	_	_	_	_	_	_
12	prescribed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	drug	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
17	salicylic	_	NOUN	_	Number=Sing	_	_	_	_
18	acid	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	ASA	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	12	_	NUM	_	NumType=Card	_	_	_	_
27	production	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	development	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	ASA	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
6	secretion	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	12	_	NUM	_	NumType=Card	_	_	_	_
12	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
13	as	_	ADV	_	_	_	_	_	_
14	well	_	ADV	_	Degree=Pos	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	p40	_	NUM	_	Number=Sing	_	_	_	_
17	monomer	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	down	_	ADP	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	12p40	_	NUM	_	NumType=Card	_	_	_	_
13	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	p40	_	PROPN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	ASA	_	PROPN	_	Number=Sing	_	_	_	_
13	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	binding	_	VERB	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	p40-kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	p40	_	NOUN	_	Number=Sing	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
32	repression	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	p40	_	NOUN	_	Number=Sing	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Addition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	ASA	_	PROPN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	vitro	_	NOUN	_	Number=Sing	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	helper	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	system	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
16	compatible	_	ADJ	_	Degree=Pos	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	plasma	_	NOUN	_	Number=Sing	_	_	_	_
19	levels	_	NOUN	_	Number=Plur	_	_	_	_
20	reached	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	during	_	ADP	_	_	_	_	_	_
22	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	therapy	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	development	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	Th1	_	DET	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	ASA	_	PROPN	_	Number=Sing	_	_	_	_
14	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	down	_	ADP	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	regulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	12	_	NUM	_	NumType=Card	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	development	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030020	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	controls	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	kappa	_	VERB	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	evidence	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
18	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	pathway	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	eukaryotic	_	ADJ	_	Degree=Pos	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	PROPN	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	participates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	many	_	ADJ	_	Degree=Pos	_	_	_	_
19	parts	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
23	program	_	NOUN	_	Number=Sing	_	_	_	_
24	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	growth	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	after	_	ADP	_	_	_	_	_	_
10	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
16	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	alpha	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Phorbol	_	PROPN	_	Number=Sing	_	_	_	_
2	ester	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	tumor	_	NOUN	_	Number=Sing	_	_	_	_
5	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	degradation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	SCONJ	_	_	_	_	_	_
23	performed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	kappa	_	VERB	_	Number=Sing	_	_	_	_
26	B	_	PROPN	_	Number=Sing	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
33	kappa	_	VERB	_	Number=Sing	_	_	_	_
34	B	_	PROPN	_	Number=Sing	_	_	_	_
35	alpha	_	NOUN	_	Number=Sing	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	expression	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Transfection	_	NOUN	_	Number=Sing	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	kappa	_	VERB	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	specifically	_	ADV	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	65	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kilodalton	_	NOUN	_	Number=Sing	_	_	_	_
19	transactivating	_	NOUN	_	Number=Sing	_	_	_	_
20	subunit	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	PROPN	_	Number=Sing	_	_	_	_
25	B.	_	PROPN	_	Number=Sing	_	_	_	_
26	Association	_	PROPN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	newly	_	ADV	_	_	_	_	_	_
30	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
32	kappa	_	VERB	_	Number=Sing	_	_	_	_
33	B	_	PROPN	_	Number=Sing	_	_	_	_
34	alpha	_	NOUN	_	Number=Sing	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	p65	_	NUM	_	Number=Sing	_	_	_	_
37	restores	_	NOUN	_	Number=Plur	_	_	_	_
38	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
39	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	NF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	kappa	_	NOUN	_	Number=Sing	_	_	_	_
44	B	_	NOUN	_	Number=Sing	_	_	_	_
45	DNA	_	NOUN	_	Number=Sing	_	_	_	_
46	binding	_	VERB	_	Number=Sing	_	_	_	_
47	activity	_	NOUN	_	Number=Sing	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	prolongs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	survival	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
54	labile	_	ADJ	_	Number=Sing	_	_	_	_
55	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	controls	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	VERB	_	Number=Sing	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	means	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
24	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	pathway	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300212	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	T-lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	line	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	hypochlorous	_	ADJ	_	Degree=Pos	_	_	_	_
16	acid	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Reactive	_	ADJ	_	Degree=Pos	_	_	_	_
2	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
3	species	_	NOUN	_	Number=Plur	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	ROS	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	such	_	ADJ	_	Degree=Pos	_	_	_	_
8	as	_	SCONJ	_	_	_	_	_	_
9	hydrogen	_	ADJ	_	Degree=Pos	_	_	_	_
10	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
11	serve	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
14	messengers	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	hence	_	ADV	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	replication	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	human	_	ADJ	_	Degree=Pos	_	_	_	_
35	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
36	virus	_	NOUN	_	Number=Sing	_	_	_	_
37	type	_	NOUN	_	Number=Sing	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	HIV	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	human	_	ADJ	_	Degree=Pos	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	During	_	ADP	_	_	_	_	_	_
2	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	reactions	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	many	_	ADJ	_	Degree=Pos	_	_	_	_
6	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
7	species	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	one	_	NUM	_	NumType=Card	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Int	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	hypochlorous	_	ADJ	_	Degree=Pos	_	_	_	_
16	acid	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	HOCl	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	microbicidal	_	ADJ	_	Degree=Pos	_	_	_	_
27	effects	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	polymorphonuclear	_	ADJ	_	Degree=Pos	_	_	_	_
32	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	T-lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	line	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	micromolar	_	ADJ	_	Degree=Pos	_	_	_	_
9	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	HOCl	_	NOUN	_	Number=Sing	_	_	_	_
12	promoted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	appearance	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
24	p50/p65	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	even	_	ADV	_	_	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	absence	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	de	_	X	_	Number=Sing	_	_	_	_
39	novo	_	PROPN	_	Number=Sing	_	_	_	_
40	protein	_	NOUN	_	Number=Sing	_	_	_	_
41	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
10	subunits	_	NOUN	_	Number=Plur	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	both	_	DET	_	_	_	_	_	_
17	IkappaB	_	ADJ	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	p105	_	NOUN	_	Number=Sing	_	_	_	_
23	processing	_	NOUN	_	Number=Sing	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	treatment	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	very	_	ADV	_	_	_	_	_	_
7	effective	_	ADJ	_	Degree=Pos	_	_	_	_
8	when	_	ADV	_	PronType=Int	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	subjected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	hyperthermia	_	NOUN	_	Number=Sing	_	_	_	_
14	before	_	SCONJ	_	_	_	_	_	_
15	being	_	AUX	_	VerbForm=Ger	_	_	_	_
16	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	HOCl	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Various	_	ADJ	_	Degree=Pos	_	_	_	_
2	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	such	_	ADJ	_	Degree=Pos	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	pyrrolidine	_	NOUN	_	Number=Sing	_	_	_	_
7	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	p	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	bromophenacyl	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	bromide	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	nordihydroguaiaretic	_	ADJ	_	Degree=Pos	_	_	_	_
16	acid	_	NOUN	_	Number=Sing	_	_	_	_
17	could	_	AUX	_	VerbForm=Fin	_	_	_	_
18	strongly	_	ADV	_	_	_	_	_	_
19	reduce	_	VERB	_	VerbForm=Inf	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	translocation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	importance	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
30	species	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	transduction	_	NOUN	_	Number=Sing	_	_	_	_
34	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	ACH	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	HOCl	_	NOUN	_	Number=Sing	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	H2O2	_	PROPN	_	Number=Sing	_	_	_	_
12	released	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	tumour	_	NOUN	_	Number=Sing	_	_	_	_
14	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	TNF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	supernatants	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	importance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	release	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	HOCl	_	PROPN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	H2O2	_	PROPN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	fact	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	:	_	PUNCT	_	_	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	1	_	X	_	_	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	appearance	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
35	promoted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	;	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	2	_	X	_	_	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	synergism	_	NOUN	_	Number=Sing	_	_	_	_
45	between	_	ADP	_	_	_	_	_	_
46	TNF	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	alpha	_	NOUN	_	Number=Sing	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	HOCl	_	PROPN	_	Number=Sing	_	_	_	_
51	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
52	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Collectively	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	HOCl	_	PROPN	_	Number=Sing	_	_	_	_
8	should	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	considered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
14	species	_	NOUN	_	Number=Plur	_	_	_	_
15	capable	_	ADJ	_	Degree=Pos	_	_	_	_
16	of	_	SCONJ	_	_	_	_	_	_
17	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	T-lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	line	_	NOUN	_	Number=Sing	_	_	_	_
26	through	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	transduction	_	NOUN	_	Number=Sing	_	_	_	_
29	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
30	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
31	ROS	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	having	_	VERB	_	VerbForm=Ger	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	long	_	ADJ	_	Degree=Pos	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	distance	_	NOUN	_	Number=Sing	_	_	_	_
39	effect	_	NOUN	_	Number=Sing	_	_	_	_
40	through	_	ADP	_	_	_	_	_	_
41	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
42	TNF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	alpha	_	NOUN	_	Number=Sing	_	_	_	_
45	release	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300215	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	interferon	_	NOUN	_	Number=Sing	_	_	_	_
3	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	Intron	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	exon	_	PROPN	_	Number=Sing	_	_	_	_
4	organization	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	functional	_	ADJ	_	Degree=Pos	_	_	_	_
7	analysis	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	5	_	NUM	_	NumType=Card	_	_	_	_
10	'-	_	PUNCT	_	_	_	_	_	_
11	flanking	_	VERB	_	Number=Sing	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
2	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	IRF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
13	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	terminates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	interferon	_	NOUN	_	Number=Sing	_	_	_	_
18	beta	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	interferon	_	NOUN	_	Number=Sing	_	_	_	_
23	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	isolated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
9	DNA	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	IRF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	determined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	intron	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	exon	_	ADJ	_	Number=Sing	_	_	_	_
22	structure	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	IRF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	mapped	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	major	_	ADJ	_	Degree=Pos	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	initiation	_	NOUN	_	Number=Sing	_	_	_	_
36	site	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	number	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	potential	_	ADJ	_	Degree=Pos	_	_	_	_
43	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
44	elements	_	NOUN	_	Number=Plur	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	5'-	_	NOUN	_	Number=Sing	_	_	_	_
48	flanking	_	VERB	_	Number=Sing	_	_	_	_
49	region	_	NOUN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	localized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	IRF	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	2	_	NUM	_	NumType=Card	_	_	_	_
57	gene	_	NOUN	_	Number=Sing	_	_	_	_
58	on	_	ADP	_	_	_	_	_	_
59	human	_	ADJ	_	Degree=Pos	_	_	_	_
60	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
61	4	_	NUM	_	NumType=Card	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IRF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	region	_	NOUN	_	Number=Sing	_	_	_	_
7	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	CpG	_	PROPN	_	Number=Sing	_	_	_	_
10	island	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	several	_	ADJ	_	Degree=Pos	_	_	_	_
14	GC	_	NOUN	_	Number=Sing	_	_	_	_
15	boxes	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	putative	_	ADJ	_	Degree=Pos	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	CAAT	_	NOUN	_	Number=Sing	_	_	_	_
30	box	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	but	_	CCONJ	_	_	_	_	_	_
33	no	_	DET	_	_	_	_	_	_
34	TATA	_	NOUN	_	Number=Sing	_	_	_	_
35	box	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
10	reporter	_	NOUN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	region	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	interferons	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	interferon	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	gamma	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	interferon	_	NOUN	_	Number=Sing	_	_	_	_
34	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	which	_	PRON	_	PronType=Rel	_	_	_	_
4	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	inductions	_	NOUN	_	Number=Plur	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	as	_	SCONJ	_	_	_	_	_	_
10	being	_	AUX	_	VerbForm=Ger	_	_	_	_
11	confined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	40	_	NUM	_	NumType=Card	_	_	_	_
14	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
15	5'	_	NUM	_	Number=Plur	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	major	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	initiation	_	NOUN	_	Number=Sing	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	SCONJ	_	_	_	_	_	_
23	testing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	series	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	clones	_	NOUN	_	Number=Plur	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	IRF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	elements	_	NOUN	_	Number=Plur	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	shared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	other	_	ADJ	_	Degree=Pos	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	including	_	VERB	_	VerbForm=Ger	_	_	_	_
16	interferon	_	NOUN	_	Number=Sing	_	_	_	_
17	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	interferon	_	NOUN	_	Number=Sing	_	_	_	_
22	beta	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	interferon	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
28	genes	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	interferon	_	NOUN	_	Number=Sing	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	not	_	ADV	_	_	_	_	_	_
10	only	_	ADV	_	_	_	_	_	_
11	triggers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	interferon	_	NOUN	_	Number=Sing	_	_	_	_
17	signal	_	NOUN	_	Number=Sing	_	_	_	_
18	transduction	_	NOUN	_	Number=Sing	_	_	_	_
19	pathway	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	also	_	ADV	_	_	_	_	_	_
23	may	_	AUX	_	VerbForm=Fin	_	_	_	_
24	play	_	VERB	_	VerbForm=Inf	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	role	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	SCONJ	_	_	_	_	_	_
28	limiting	_	VERB	_	VerbForm=Ger	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	duration	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	response	_	NOUN	_	Number=Sing	_	_	_	_
34	by	_	SCONJ	_	_	_	_	_	_
35	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	IRF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_
43	Document	_	NOUN	_	Number=Sing	_	_	_	_
44	00300221	_	NUM	_	NumType=Card	_	_	_	_
45	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_

1	B	_	X	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	Rel	_	VERB	_	Number=Sing	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	CD3	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	peripheral	_	NOUN	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	markedly	_	ADV	_	_	_	_	_	_
5	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	Rel	_	NOUN	_	Number=Sing	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
14	mAb	_	NOUN	_	Number=Sing	_	_	_	_
15	OKT3	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	exerted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	specifically	_	ADV	_	_	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	Rel	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	mAb	_	PROPN	_	Number=Sing	_	_	_	_
18	OKT3	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	not	_	ADV	_	_	_	_	_	_
22	that	_	ADV	_	Number=Sing|PronType=Dem	_	_	_	_
23	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	PMA	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	judged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	by	_	SCONJ	_	_	_	_	_	_
4	supershifting	_	VERB	_	VerbForm=Ger	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	complexes	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	Abs	_	NOUN	_	Number=Sing	_	_	_	_
12	recognizing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	components	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	Rel	_	NOUN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	family	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	p50/p65	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	Rel	_	NOUN	_	Number=Sing	_	_	_	_
30	A	_	X	_	_	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	heterodimeric	_	ADJ	_	Degree=Pos	_	_	_	_
33	form	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	primarily	_	ADV	_	_	_	_	_	_
41	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	concentration	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	20	_	NUM	_	NumType=Card	_	_	_	_
14	U/ml	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	exerted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	T	_	ADP	_	Number=Sing	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Indeed	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	pretreated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	10	_	NUM	_	NumType=Card	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	able	_	ADJ	_	Degree=Pos	_	_	_	_
11	so	_	ADV	_	_	_	_	_	_
12	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	OKT3	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Soluble	_	ADJ	_	Degree=Pos	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	appear	_	VERB	_	VerbForm=Inf	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	involved	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	hand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	up	_	ADP	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	regulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	CD80	_	PROPN	_	Number=Sing	_	_	_	_
12	Ag	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
20	incubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	OKT3	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	after	_	ADP	_	_	_	_	_	_
28	addition	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	10	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	anti-CD28	_	PROPN	_	Number=Sing	_	_	_	_
37	mAb	_	PROPN	_	Number=Sing	_	_	_	_
38	CLB	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	CD28	_	PROPN	_	Number=Sing	_	_	_	_
41	/	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	restores	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	NF	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	kappa	_	NOUN	_	Number=Sing	_	_	_	_
48	B	_	NOUN	_	Number=Sing	_	_	_	_
49	/	_	PUNCT	_	_	_	_	_	_
50	Rel	_	PROPN	_	Number=Sing	_	_	_	_
51	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
52	activity	_	NOUN	_	Number=Sing	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	IL	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	10	_	NUM	_	NumType=Card	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
59	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	Rel	_	NOUN	_	Number=Sing	_	_	_	_
10	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
11	might	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	ascribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	lack	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
19	between	_	ADP	_	_	_	_	_	_
20	accessory	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	down	_	ADP	_	_	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	regulation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
34	molecule	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	such	_	ADJ	_	Degree=Pos	_	_	_	_
37	as	_	ADP	_	_	_	_	_	_
38	CD80	_	PROPN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	10	_	NUM	_	NumType=Card	_	_	_	_
45	on	_	ADP	_	_	_	_	_	_
46	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	10	_	NUM	_	NumType=Card	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	Rel	_	NOUN	_	Number=Sing	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	CD3	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	inappropriate	_	ADJ	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	physiopathologic	_	ADJ	_	Degree=Pos	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	number	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	diseases	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	such	_	ADJ	_	Degree=Pos	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	infection	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
26	findings	_	NOUN	_	Number=Plur	_	_	_	_
27	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	possibility	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	SCONJ	_	_	_	_	_	_
31	using	_	VERB	_	VerbForm=Ger	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
36	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	undesirable	_	ADJ	_	Degree=Pos	_	_	_	_
38	activation	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
41	transcription	_	NOUN	_	Number=Sing	_	_	_	_
42	factors	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300223	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
2	cooperates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	pathway	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	synergistically	_	ADV	_	_	_	_	_	_
11	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	LTR	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	via	_	ADP	_	_	_	_	_	_
18	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
19	TRE	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	like	_	ADP	_	Degree=Pos	_	_	_	_
22	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	elements	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Activating	_	VERB	_	VerbForm=Ger	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	AP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
11	TPA	_	PROPN	_	Number=Sing	_	_	_	_
12	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
13	elements	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TRE	_	X	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	downstream	_	ADP	_	_	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	initiation	_	NOUN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	U5	_	PROPN	_	Number=Sing	_	_	_	_
28	region	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	HIV	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	long	_	ADJ	_	Degree=Pos	_	_	_	_
35	terminal	_	NOUN	_	Number=Sing	_	_	_	_
36	repeat	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	LTR	_	PROPN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	elements	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	DSE	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	AP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	CREB	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	ATF	_	NOUN	_	Number=Sing	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factors	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	DSE	_	PROPN	_	Number=Sing	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	cAMP	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
13	elements	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	CRE	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	since	_	SCONJ	_	_	_	_	_	_
19	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
20	mediated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	signals	_	NOUN	_	Number=Plur	_	_	_	_
23	elicited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	cholera	_	NOUN	_	Number=Sing	_	_	_	_
26	toxin	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	Ctx	_	PROPN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	potent	_	ADJ	_	Degree=Pos	_	_	_	_
33	activator	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
39	protein	_	NOUN	_	Number=Sing	_	_	_	_
40	kinase	_	NOUN	_	Number=Sing	_	_	_	_
41	A	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	PKA	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	signal	_	NOUN	_	Number=Sing	_	_	_	_
46	transduction	_	NOUN	_	Number=Sing	_	_	_	_
47	pathway	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	HIV	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	DSE	_	NOUN	_	Number=Sing	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	synergy	_	NOUN	_	Number=Sing	_	_	_	_
19	elicited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	combination	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	Ctx	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Ctx	_	PROPN	_	Number=Sing	_	_	_	_
2	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1beta	_	PROPN	_	Number=Sing	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
13	increase	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	p24	_	NUM	_	Number=Sing	_	_	_	_
16	antigen	_	NOUN	_	Number=Sing	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	U1	_	PROPN	_	Number=Sing	_	_	_	_
20	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Transfection	_	NOUN	_	Number=Sing	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	LTR	_	NOUN	_	Number=Sing	_	_	_	_
5	reporter	_	NOUN	_	Number=Sing	_	_	_	_
6	constructs	_	NOUN	_	Number=Plur	_	_	_	_
7	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	mutation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	DSE	_	NOUN	_	Number=Sing	_	_	_	_
13	sites	_	NOUN	_	Number=Plur	_	_	_	_
14	abrogated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	LTR	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
19	synergy	_	NOUN	_	Number=Sing	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	Ctx	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	whereas	_	SCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	synergy	_	NOUN	_	Number=Sing	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	Ctx	_	PROPN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1beta	_	PROPN	_	Number=Sing	_	_	_	_
36	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
37	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
40	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1beta	_	PROPN	_	Number=Sing	_	_	_	_
45	cooperate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
46	differently	_	ADV	_	_	_	_	_	_
47	with	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
50	/	_	PUNCT	_	_	_	_	_	_
51	PKA	_	PROPN	_	Number=Sing	_	_	_	_
52	activation	_	NOUN	_	Number=Sing	_	_	_	_
53	pathway	_	NOUN	_	Number=Sing	_	_	_	_
54	to	_	PART	_	_	_	_	_	_
55	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
56	HIV	_	PROPN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	1	_	NUM	_	NumType=Card	_	_	_	_
59	expression	_	NOUN	_	Number=Sing	_	_	_	_
60	in	_	ADP	_	_	_	_	_	_
61	U1	_	PROPN	_	Number=Sing	_	_	_	_
62	cells	_	NOUN	_	Number=Plur	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	DSE	_	PROPN	_	Number=Sing	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	TRE	_	NOUN	_	Number=Sing	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	assessed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	effect	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	agonist	_	ADJ	_	Number=Sing	_	_	_	_
16	combinations	_	NOUN	_	Number=Plur	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
2	as	_	ADV	_	_	_	_	_	_
3	well	_	ADV	_	Degree=Pos	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1beta	_	PROPN	_	Number=Sing	_	_	_	_
8	cooperated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	Ctx	_	PROPN	_	Number=Sing	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	AP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	TRE	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	like	_	ADJ	_	_	_	_	_	_
9	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
12	DSE	_	NOUN	_	Number=Sing	_	_	_	_
13	sites	_	NOUN	_	Number=Plur	_	_	_	_
14	within	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	5'-	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
17	untranslated	_	ADJ	_	Degree=Pos	_	_	_	_
18	leader	_	NOUN	_	Number=Sing	_	_	_	_
19	can	_	AUX	_	VerbForm=Fin	_	_	_	_
20	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	cooperativity	_	NOUN	_	Number=Sing	_	_	_	_
24	between	_	ADP	_	_	_	_	_	_
25	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	PKA	_	PROPN	_	Number=Sing	_	_	_	_
31	pathway	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	DSE	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	TRE	_	NOUN	_	Number=Sing	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
10	CREB	_	PROPN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	ATF	_	PROPN	_	Number=Sing	_	_	_	_
13	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	DSE	_	NOUN	_	Number=Sing	_	_	_	_
26	bind	_	NOUN	_	Number=Sing	_	_	_	_
27	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
28	composed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	both	_	CCONJ	_	_	_	_	_	_
31	AP	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	CREB	_	NOUN	_	Number=Sing	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	ATF	_	NOUN	_	Number=Sing	_	_	_	_
38	proteins	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1997	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300229	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Signaling	_	VERB	_	Number=Sing	_	_	_	_
2	events	_	NOUN	_	Number=Plur	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	toll	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	like	_	ADP	_	Degree=Pos	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_
14	Human	_	ADJ	_	Degree=Pos	_	_	_	_
15	Toll	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	like	_	ADP	_	Degree=Pos	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	TLR2	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	signaling	_	NOUN	_	Number=Sing	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	that	_	PRON	_	PronType=Rel	_	_	_	_
28	responds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	LPS	_	PROPN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	investigate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	further	_	ADV	_	Degree=Cmp	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	events	_	NOUN	_	Number=Plur	_	_	_	_
8	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	TLR2	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	LPS	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	TLR2	_	PROPN	_	Number=Sing	_	_	_	_
5	associates	_	VERB	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	high	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	affinity	_	NOUN	_	Number=Sing	_	_	_	_
11	LPS	_	NOUN	_	Number=Sing	_	_	_	_
12	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	membrane	_	NOUN	_	Number=Sing	_	_	_	_
15	CD14	_	PROPN	_	Number=Sing	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	LPS	_	NOUN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	complex	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	LPS	_	NOUN	_	Number=Sing	_	_	_	_
27	treatment	_	NOUN	_	Number=Sing	_	_	_	_
28	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	oligomerization	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	TLR2	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Concomitant	_	ADJ	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	oligomerization	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1R	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	kinase	_	PROPN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	IRAK	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	recruited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	TLR2	_	PROPN	_	Number=Sing	_	_	_	_
21	complex	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	deletion	_	NOUN	_	Number=Sing	_	_	_	_
3	variants	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	TLR2	_	NOUN	_	Number=Sing	_	_	_	_
6	lacking	_	VERB	_	Number=Sing	_	_	_	_
7	C-	_	NOUN	_	Number=Sing	_	_	_	_
8	terminal	_	NOUN	_	Number=Sing	_	_	_	_
9	13	_	NUM	_	NumType=Card	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	141	_	NUM	_	NumType=Card	_	_	_	_
12	aa	_	NOUN	_	Number=Sing	_	_	_	_
13	fail	_	VERB	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	recruit	_	VERB	_	VerbForm=Inf	_	_	_	_
16	IRAK	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	inability	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	mutants	_	NOUN	_	Number=Plur	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	transmit	_	VERB	_	VerbForm=Inf	_	_	_	_
29	LPS	_	PROPN	_	Number=Sing	_	_	_	_
30	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
31	signaling	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	both	_	DET	_	_	_	_	_	_
4	deletion	_	NOUN	_	Number=Sing	_	_	_	_
5	mutants	_	NOUN	_	Number=Plur	_	_	_	_
6	could	_	AUX	_	VerbForm=Fin	_	_	_	_
7	still	_	ADV	_	_	_	_	_	_
8	form	_	VERB	_	VerbForm=Inf	_	_	_	_
9	complexes	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	wild	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	TLR2	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	act	_	VERB	_	VerbForm=Inf	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	negative	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	DN	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	fashion	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	block	_	VERB	_	VerbForm=Inf	_	_	_	_
28	TLR2	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
31	signal	_	NOUN	_	Number=Sing	_	_	_	_
32	transduction	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	DN	_	PROPN	_	Number=Sing	_	_	_	_
2	constructs	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	IRAK	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	TNF	_	PROPN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	when	_	ADV	_	PronType=Rel	_	_	_	_
26	coexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	TLR2	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	abrogate	_	VERB	_	VerbForm=Inf	_	_	_	_
31	TLR2	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	NF	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	conserved	_	VERB	_	Degree=Pos	_	_	_	_
6	signaling	_	NOUN	_	Number=Sing	_	_	_	_
7	pathway	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	TLR2	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1Rs	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
18	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	TLR2	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	DN	_	PROPN	_	Number=Sing	_	_	_	_
26	variants	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300232	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p16	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	E2F	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	alterations	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	MTS1	_	PROPN	_	Number=Sing	_	_	_	_
8	tumor	_	NOUN	_	Number=Sing	_	_	_	_
9	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
13	9p21	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	p16	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kinase	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	4	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	6	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	tumorigenesis	_	NOUN	_	Number=Sing	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	not	_	PART	_	_	_	_	_	_
36	yet	_	ADV	_	_	_	_	_	_
37	clear	_	ADJ	_	Degree=Pos	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	kinases	_	NOUN	_	Number=Plur	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	interaction	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	E2F	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	subsequently	_	ADV	_	_	_	_	_	_
25	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	S	_	NOUN	_	Number=Sing	_	_	_	_
30	phase	_	NOUN	_	Number=Sing	_	_	_	_
31	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	such	_	ADJ	_	Degree=Pos	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
37	kinase	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	role	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	p16	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	presumed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	there	_	PRON	_	_	_	_	_	_
14	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	no	_	DET	_	_	_	_	_	_
16	proof	_	NOUN	_	Number=Sing	_	_	_	_
17	so	_	ADV	_	_	_	_	_	_
18	far	_	ADV	_	Degree=Pos	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	loss	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
23	tumor	_	NOUN	_	Number=Sing	_	_	_	_
24	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	really	_	ADV	_	_	_	_	_	_
27	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	E2F	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	mediated	_	VERB	_	Degree=Pos	_	_	_	_
31	regulations	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	thymidine	_	PROPN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	normal	_	ADJ	_	Degree=Pos	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	p16-negative	_	ADJ	_	Degree=Pos	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	acute	_	NOUN	_	Number=Sing	_	_	_	_
21	lymphoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
22	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	lines	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	MOLT	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	4	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	CEM	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	normal	_	ADJ	_	Degree=Pos	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	MOLT	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	CEM	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	cycle	_	NOUN	_	Number=Sing	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	thymidine	_	PROPN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	much	_	ADV	_	_	_	_	_	_
24	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
25	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
29	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
33	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
34	kinase	_	NOUN	_	Number=Sing	_	_	_	_
35	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p16	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	normal	_	ADJ	_	Degree=Pos	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	arrest	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	G1	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	without	_	ADP	_	_	_	_	_	_
17	effect	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	growth	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	MOLT	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	4	_	NUM	_	NumType=Card	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	CEM	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	although	_	SCONJ	_	_	_	_	_	_
31	all	_	DET	_	_	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
34	express	_	ADJ	_	Degree=Pos	_	_	_	_
35	functional	_	ADJ	_	Degree=Pos	_	_	_	_
36	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
37	protein	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Nevertheless	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	transient	_	ADJ	_	Degree=Pos	_	_	_	_
10	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	p16	_	NOUN	_	Number=Sing	_	_	_	_
13	reestablished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	normal	_	ADJ	_	Degree=Pos	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	thymidine	_	PROPN	_	Number=Sing	_	_	_	_
19	kinase	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	paralleled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	increase	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	underphosphorylated	_	ADJ	_	Degree=Pos	_	_	_	_
28	form	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	decrease	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	free	_	ADJ	_	Degree=Pos	_	_	_	_
36	E2F	_	NOUN	_	Number=Sing	_	_	_	_
37	bound	_	NOUN	_	Degree=Pos	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
40	motif	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
44	kinase	_	NOUN	_	Number=Sing	_	_	_	_
45	promoter	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	loss	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	p16	_	NOUN	_	Number=Sing	_	_	_	_
7	causes	_	NOUN	_	Number=Plur	_	_	_	_
8	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	precursor	_	NOUN	_	Number=Sing	_	_	_	_
13	pathway	_	NOUN	_	Number=Sing	_	_	_	_
14	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
15	via	_	ADP	_	_	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	E2F	_	PROPN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
22	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
23	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300233	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Modulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	beta	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
14	results	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	opposing	_	ADJ	_	VerbForm=Ger	_	_	_	_
17	effects	_	NOUN	_	Number=Plur	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	chronically	_	ADV	_	_	_	_	_	_
23	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	proportion	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	individuals	_	NOUN	_	Number=Plur	_	_	_	_
8	experience	_	NOUN	_	Number=Sing	_	_	_	_
9	episodes	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	localized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	systemic	_	ADJ	_	Degree=Pos	_	_	_	_
14	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
15	infections	_	NOUN	_	Number=Plur	_	_	_	_
16	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	Gram	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	negative	_	ADJ	_	Degree=Pos	_	_	_	_
21	bacteria	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Many	_	ADJ	_	Degree=Pos	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
5	side	_	NOUN	_	Number=Sing	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	infections	_	NOUN	_	Number=Plur	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	primarily	_	ADV	_	_	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	LPS	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	constituent	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	wall	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	Gram	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	negative	_	ADJ	_	Degree=Pos	_	_	_	_
37	bacteria	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	examines	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
7	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	LPS	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	HIV	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	U1	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	chronically	_	ADV	_	_	_	_	_	_
25	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	HIV	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	U1	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	LPS	_	PROPN	_	Number=Sing	_	_	_	_
7	alone	_	ADV	_	_	_	_	_	_
8	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	significantly	_	ADV	_	_	_	_	_	_
18	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
23	colony	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	GM	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	CSF	_	PROPN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Costimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	U1	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	LPS	_	NOUN	_	Number=Sing	_	_	_	_
7	plus	_	CCONJ	_	_	_	_	_	_
8	GM	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CSF	_	NOUN	_	Number=Sing	_	_	_	_
11	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	steady	_	ADJ	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	state	_	NOUN	_	Number=Sing	_	_	_	_
19	levels	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	HIV	_	PROPN	_	Number=Sing	_	_	_	_
22	RNA	_	PROPN	_	Number=Sing	_	_	_	_
23	;	_	PUNCT	_	_	_	_	_	_
24	however	_	ADV	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	only	_	ADV	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	weak	_	ADJ	_	Degree=Pos	_	_	_	_
29	induction	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	HIV	_	NOUN	_	Number=Sing	_	_	_	_
32	long	_	ADJ	_	Degree=Pos	_	_	_	_
33	terminal	_	NOUN	_	Number=Sing	_	_	_	_
34	repeat	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	which	_	PRON	_	PronType=Rel	_	_	_	_
40	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
41	not	_	PART	_	_	_	_	_	_
42	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	with	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
49	transcription	_	NOUN	_	Number=Sing	_	_	_	_
50	factor	_	NOUN	_	Number=Sing	_	_	_	_
51	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
52	factor	_	NOUN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	kappa	_	NOUN	_	Number=Sing	_	_	_	_
55	B	_	NOUN	_	Number=Sing	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
58	noted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Costimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	LPS	_	NOUN	_	Number=Sing	_	_	_	_
6	plus	_	CCONJ	_	_	_	_	_	_
7	GM	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	CSF	_	NOUN	_	Number=Sing	_	_	_	_
10	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	8	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	beta	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	6	_	NUM	_	NumType=Card	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	but	_	CCONJ	_	_	_	_	_	_
31	not	_	ADV	_	_	_	_	_	_
32	TNF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	alpha	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	ra	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	LPS	_	PROPN	_	Number=Sing	_	_	_	_
11	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	GM	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	CSF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	involved	_	ADJ	_	Degree=Pos	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	LPS	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	mediated	_	VERB	_	Degree=Pos	_	_	_	_
35	viral	_	ADJ	_	Degree=Pos	_	_	_	_
36	production	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	regard	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	LPS	_	PROPN	_	Number=Sing	_	_	_	_
9	plus	_	CCONJ	_	_	_	_	_	_
10	GM	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	CSF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	effect	_	NOUN	_	Number=Sing	_	_	_	_
21	closely	_	ADV	_	_	_	_	_	_
22	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	beta	_	NOUN	_	Number=Sing	_	_	_	_
30	release	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	particular	_	ADJ	_	Degree=Pos	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	up	_	ADP	_	_	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	regulation	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1ra	_	PROPN	_	Number=Sing	_	_	_	_
45	production	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	balance	_	NOUN	_	Number=Sing	_	_	_	_
5	between	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	endogenously	_	ADV	_	_	_	_	_	_
8	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	viral	_	ADJ	_	Degree=Pos	_	_	_	_
10	inducer	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	beta	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1ra	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	may	_	AUX	_	VerbForm=Fin	_	_	_	_
26	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	important	_	ADJ	_	Degree=Pos	_	_	_	_
29	pathway	_	NOUN	_	Number=Sing	_	_	_	_
30	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	modulation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	HIV	_	NOUN	_	Number=Sing	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	from	_	ADP	_	_	_	_	_	_
37	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300235	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
4	blood	_	NOUN	_	Number=Sing	_	_	_	_
5	T-lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	Tax	_	NOUN	_	Number=Sing	_	_	_	_
12	mutants	_	NOUN	_	Number=Plur	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	different	_	ADJ	_	Degree=Pos	_	_	_	_
15	trans	_	NOUN	_	Number=Plur	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	phenotypes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Tax1	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	trans	_	NOUN	_	Number=Plur	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	activator	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	Human	_	ADJ	_	Degree=Pos	_	_	_	_
11	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
12	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	type	_	NOUN	_	Number=Sing	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	many	_	ADJ	_	Degree=Pos	_	_	_	_
27	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
28	genes	_	NOUN	_	Number=Plur	_	_	_	_
29	through	_	ADP	_	_	_	_	_	_
30	interaction	_	NOUN	_	Number=Sing	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	at	_	ADV	_	_	_	_	_	_
33	least	_	ADV	_	Degree=Sup	_	_	_	_
34	three	_	NUM	_	NumType=Card	_	_	_	_
35	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
36	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	factors	_	NOUN	_	Number=Plur	_	_	_	_
39	;	_	PUNCT	_	_	_	_	_	_
40	CREB	_	NOUN	_	Number=Sing	_	_	_	_
41	/	_	PUNCT	_	_	_	_	_	_
42	ATF	_	PROPN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	NF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	SRF	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	Tax1	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	considered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	critical	_	ADJ	_	Degree=Pos	_	_	_	_
15	event	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
18	transformation	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	elucidate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	each	_	DET	_	_	_	_	_	_
7	Tax1	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	pathway	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
14	transformation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	introduced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	Tax1	_	NOUN	_	Number=Sing	_	_	_	_
19	mutants	_	NOUN	_	Number=Plur	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	different	_	ADJ	_	Degree=Pos	_	_	_	_
22	trans	_	NOUN	_	Number=Plur	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
25	phenotypes	_	NOUN	_	Number=Plur	_	_	_	_
26	into	_	ADP	_	_	_	_	_	_
27	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
28	blood	_	NOUN	_	Number=Sing	_	_	_	_
29	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	PBL	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	retroviral	_	ADJ	_	Degree=Pos	_	_	_	_
35	vectors	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	PBLs	_	NOUN	_	Number=Plur	_	_	_	_
5	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	pathway	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	growth	_	NOUN	_	Number=Sing	_	_	_	_
20	response	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
6	expansion	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	CD4	_	PROPN	_	Number=Sing	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_

1	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	which	_	PRON	_	PronType=Rel	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	characteristic	_	ADJ	_	Degree=Pos	_	_	_	_
7	result	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	infection	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	CREB	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	ATF	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	SRF	_	PROPN	_	Number=Sing	_	_	_	_
22	pathways	_	NOUN	_	Number=Plur	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	also	_	ADV	_	_	_	_	_	_
25	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300238	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	Janus	_	PROPN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	STAT5a	_	PROPN	_	Number=Sing	_	_	_	_
9	pathway	_	NOUN	_	Number=Sing	_	_	_	_
10	after	_	ADP	_	_	_	_	_	_
11	CD40	_	PROPN	_	Number=Sing	_	_	_	_
12	triggering	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	not	_	ADV	_	_	_	_	_	_
18	of	_	SCONJ	_	_	_	_	_	_
19	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	B	_	NOUN	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	CD40/CD40	_	PROPN	_	Number=Sing	_	_	_	_
2	ligand	_	NOUN	_	Number=Sing	_	_	_	_
3	interactions	_	NOUN	_	Number=Plur	_	_	_	_
4	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	key	_	ADJ	_	Degree=Pos	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	immune	_	ADJ	_	Degree=Pos	_	_	_	_
11	responses	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	signal	_	NOUN	_	Number=Sing	_	_	_	_
3	transduction	_	NOUN	_	Number=Sing	_	_	_	_
4	events	_	NOUN	_	Number=Plur	_	_	_	_
5	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	cross	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	linking	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	CD40	_	PROPN	_	Number=Sing	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	widely	_	ADV	_	_	_	_	_	_
17	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	lines	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	little	_	ADV	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	about	_	ADP	_	_	_	_	_	_
28	signaling	_	VERB	_	Number=Sing	_	_	_	_
29	following	_	VERB	_	VerbForm=Ger	_	_	_	_
30	CD40	_	NOUN	_	Number=Sing	_	_	_	_
31	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
36	tonsillar	_	ADJ	_	Degree=Pos	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	CD40	_	PROPN	_	Number=Sing	_	_	_	_
7	pathway	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	highly	_	ADV	_	_	_	_	_	_
10	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	CD40	_	PROPN	_	Number=Sing	_	_	_	_
3	triggering	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	similar	_	ADJ	_	Degree=Pos	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	complex	_	NOUN	_	Number=Sing	_	_	_	_
25	occurred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	both	_	DET	_	_	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	preparations	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	components	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	complexes	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	different	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	B	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	because	_	SCONJ	_	_	_	_	_	_
20	p50	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	part	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	complex	_	NOUN	_	Number=Sing	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	CD40	_	PROPN	_	Number=Sing	_	_	_	_
32	triggering	_	VERB	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	both	_	CCONJ	_	_	_	_	_	_
35	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	B	_	ADJ	_	Degree=Pos	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	whereas	_	SCONJ	_	_	_	_	_	_
41	p65	_	NOUN	_	Number=Sing	_	_	_	_
42	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
43	only	_	ADV	_	_	_	_	_	_
44	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	B	_	ADJ	_	Number=Sing	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	although	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	Janus	_	PROPN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
10	kinase	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	CD40	_	PROPN	_	Number=Sing	_	_	_	_
15	molecules	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	Janus	_	PROPN	_	Number=Sing	_	_	_	_
25	kinase	_	NOUN	_	Number=Sing	_	_	_	_
26	3	_	NUM	_	NumType=Card	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	induction	_	NOUN	_	Number=Sing	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	only	_	ADV	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	CD40	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	activated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
36	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
40	induction	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	STAT5a	_	PROPN	_	Number=Sing	_	_	_	_
43	DNA	_	NOUN	_	Number=Sing	_	_	_	_
44	binding	_	VERB	_	Number=Sing	_	_	_	_
45	activity	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	signals	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	following	_	VERB	_	VerbForm=Ger	_	_	_	_
16	CD40	_	PROPN	_	Number=Sing	_	_	_	_
17	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	observation	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	detection	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	normal	_	ADJ	_	Degree=Pos	_	_	_	_
10	CD40	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	patients	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	CD40	_	PROPN	_	Number=Sing	_	_	_	_
19	ligand	_	NOUN	_	Number=Sing	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_
21	hyper	_	NOUN	_	Number=Sing	_	_	_	_
22	IgM	_	PROPN	_	Number=Sing	_	_	_	_
23	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	whom	_	PRON	_	PronType=Rel	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	defect	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	CD40	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
37	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300243	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	kappa	_	VERB	_	Number=Sing	_	_	_	_
6	B	_	PROPN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	line	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	determination	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
23	sites	_	NOUN	_	Number=Plur	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
26	kappa	_	VERB	_	Number=Sing	_	_	_	_
27	B	_	PROPN	_	Number=Sing	_	_	_	_
28	alpha	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	stored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
19	form	_	NOUN	_	Number=Sing	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	interaction	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
24	kappa	_	VERB	_	Number=Sing	_	_	_	_
25	B.	_	PROPN	_	Number=Sing	_	_	_	_
26	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
33	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
36	kappa	_	VERB	_	Number=Sing	_	_	_	_
37	B	_	PROPN	_	Number=Sing	_	_	_	_
38	alpha	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	which	_	PRON	_	PronType=Rel	_	_	_	_
41	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	presumed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	to	_	PART	_	_	_	_	_	_
44	be	_	AUX	_	VerbForm=Inf	_	_	_	_
45	important	_	ADJ	_	Degree=Pos	_	_	_	_
46	for	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
49	degradation	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	recently	_	ADV	_	_	_	_	_	_
4	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	establishment	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	LPS	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	free	_	ADJ	_	Degree=Pos	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	system	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	association	_	NOUN	_	Number=Sing	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	induction	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
32	kappa	_	VERB	_	Number=Sing	_	_	_	_
33	B	_	PROPN	_	Number=Sing	_	_	_	_
34	alpha	_	NOUN	_	Number=Sing	_	_	_	_
35	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	extracts	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	LPS	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	line	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	THP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	that	_	DET	_	PronType=Rel	_	_	_	_
28	specifically	_	ADV	_	_	_	_	_	_
29	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	phosphorylates	_	VERB	_	Number=Plur	_	_	_	_
32	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
33	kappa	_	VERB	_	Number=Sing	_	_	_	_
34	B	_	PROPN	_	Number=Sing	_	_	_	_
35	alpha	_	PROPN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	PROPN	_	Number=Sing	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	transiently	_	ADV	_	_	_	_	_	_
4	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	kappa	_	VERB	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	bound	_	ADJ	_	Degree=Pos	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	THP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Mutational	_	ADJ	_	Degree=Pos	_	_	_	_
2	analyses	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	kappa	_	VERB	_	Number=Sing	_	_	_	_
6	B	_	PROPN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	competition	_	NOUN	_	Number=Sing	_	_	_	_
10	experiments	_	NOUN	_	Number=Plur	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
14	peptides	_	NOUN	_	Number=Plur	_	_	_	_
15	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	major	_	ADJ	_	Degree=Pos	_	_	_	_
17	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	bound	_	ADJ	_	Degree=Pos	_	_	_	_
22	kinase	_	NOUN	_	Number=Sing	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	Ser	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	Thr	_	DET	_	Number=Sing	_	_	_	_
27	residues	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	C	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
33	acidic	_	ADJ	_	Number=Sing	_	_	_	_
34	domain	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
37	kappa	_	VERB	_	Number=Sing	_	_	_	_
38	B	_	PROPN	_	Number=Sing	_	_	_	_
39	alpha	_	PROPN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	peptide	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	C	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	terminal	_	ADJ	_	Number=Sing	_	_	_	_
15	acidic	_	ADJ	_	Number=Sing	_	_	_	_
16	domain	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	kappa	_	VERB	_	Number=Sing	_	_	_	_
20	B	_	PROPN	_	Number=Sing	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	LPS	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	as	_	ADV	_	_	_	_	_	_
34	well	_	ADV	_	Degree=Pos	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
37	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
40	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
41	kappa	_	VERB	_	Number=Sing	_	_	_	_
42	B	_	PROPN	_	Number=Sing	_	_	_	_
43	alpha	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
46	cell	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	free	_	ADJ	_	Degree=Pos	_	_	_	_
49	system	_	NOUN	_	Number=Sing	_	_	_	_
50	using	_	VERB	_	VerbForm=Ger	_	_	_	_
51	THP	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	1	_	NUM	_	NumType=Card	_	_	_	_
54	cells	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	bound	_	ADJ	_	Degree=Pos	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	involved	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
13	pathway	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	LPS	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	SCONJ	_	_	_	_	_	_
17	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	C	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	terminal	_	ADJ	_	Number=Sing	_	_	_	_
25	region	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
28	kappa	_	VERB	_	Number=Sing	_	_	_	_
29	B	_	PROPN	_	Number=Sing	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
33	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappa	_	NOUN	_	Number=Sing	_	_	_	_
39	B.I	_	PROPN	_	Number=Sing	_	_	_	_
40	kappa	_	NOUN	_	Number=Sing	_	_	_	_
41	B	_	NOUN	_	Number=Sing	_	_	_	_
42	alpha	_	NOUN	_	Number=Sing	_	_	_	_
43	complex	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300245	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	MIP1	_	PROPN	_	Number=Sing	_	_	_	_
2	alpha	_	NOUN	_	Number=Sing	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	MNP	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	novel	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	MIP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Murine	_	PROPN	_	Number=Sing	_	_	_	_
2	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
3	inflammatory	_	ADJ	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	MIP	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	equivalent	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	GOS19	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	LD78	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	AT464	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	members	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	C-C	_	NOUN	_	Number=Sing	_	_	_	_
31	family	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	low	_	ADJ	_	Degree=Pos	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	weight	_	NOUN	_	Number=Sing	_	_	_	_
38	chemokines	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	T	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	bone	_	VERB	_	Number=Sing	_	_	_	_
10	marrow	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	MIP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	GOS19	_	PROPN	_	Number=Sing	_	_	_	_
19	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
20	primitive	_	ADJ	_	Degree=Pos	_	_	_	_
21	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
22	stem	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	involved	_	ADJ	_	Degree=Pos	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	homeostatic	_	ADJ	_	Degree=Pos	_	_	_	_
32	control	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	stem	_	NOUN	_	Number=Sing	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	chemotaxis	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	responses	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	mature	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	types	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	MIP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	GOS19	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	work	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	set	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	widely	_	ADV	_	_	_	_	_	_
15	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	ICK	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	family	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	affect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	GOS19	_	PROPN	_	Number=Sing	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	member	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	ICK	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1A	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	behaves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	strong	_	ADJ	_	Degree=Pos	_	_	_	_
12	negative	_	ADJ	_	Degree=Pos	_	_	_	_
13	regulator	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	communication	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	evidence	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	pathway	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	line	_	NOUN	_	Number=Sing	_	_	_	_
18	U937	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	different	_	ADJ	_	Degree=Pos	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	ICK	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	confer	_	VERB	_	VerbForm=Inf	_	_	_	_
15	negative	_	ADJ	_	Degree=Pos	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	U937	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	evidence	_	NOUN	_	Number=Sing	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	additional	_	ADJ	_	Degree=Pos	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	MIP	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	MNP	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	overlaps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	ICK	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	site	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Interaction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	extracts	_	NOUN	_	Number=Plur	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	various	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	tissue	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	MNP	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	formation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	fast	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	migrating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	DNA	_	NOUN	_	Number=Sing	_	_	_	_
26	complexes	_	NOUN	_	Number=Plur	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	similar	_	ADJ	_	Degree=Pos	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
31	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
32	mobilities	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	mutation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	MNP	_	NOUN	_	Number=Sing	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	abrogate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	ICK	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	inactivates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	GOS19.1	_	NOUN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	U937	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	fourfold	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	MNP	_	PROPN	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	s	_	X	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	MNP	_	PROPN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	constitutes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	novel	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	s	_	X	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300247	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interferons	_	NOUN	_	Number=Plur	_	_	_	_
2	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	normal	_	ADJ	_	Degree=Pos	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	aberrant	_	ADJ	_	Degree=Pos	_	_	_	_
6	retinoic	_	ADJ	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	acid	_	ADJ	_	Degree=Pos	_	_	_	_
9	receptors	_	NOUN	_	Number=Plur	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	acute	_	ADJ	_	Degree=Pos	_	_	_	_
14	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	:	_	PUNCT	_	_	_	_	_	_
18	potentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	induction	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
27	markers	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	acute	_	ADJ	_	Degree=Pos	_	_	_	_
5	promyelocytic	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	APL	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	NB4	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	interferon	_	NOUN	_	Number=Sing	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	IFN	_	PROPN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	as	_	ADV	_	_	_	_	_	_
23	well	_	ADV	_	Degree=Pos	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	IFN	_	PROPN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	beta	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	gamma	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	results	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
40	coding	_	NOUN	_	Number=Sing	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	retinoic	_	ADJ	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	acid	_	ADJ	_	Number=Sing	_	_	_	_
45	receptor	_	NOUN	_	Number=Sing	_	_	_	_
46	type	_	NOUN	_	Number=Sing	_	_	_	_
47	alpha	_	NOUN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	RAR	_	PROPN	_	Number=Sing	_	_	_	_
50	(	_	PUNCT	_	_	_	_	_	_
51	alpha	_	NOUN	_	Number=Sing	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	)	_	PUNCT	_	_	_	_	_	_
54	and	_	CCONJ	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	specific	_	ADJ	_	Degree=Pos	_	_	_	_
59	retinoic	_	ADJ	_	Number=Sing	_	_	_	_
60	acid	_	NOUN	_	Number=Sing	_	_	_	_
61	receptor	_	NOUN	_	Number=Sing	_	_	_	_
62	PML	_	NOUN	_	Number=Sing	_	_	_	_
63	-	_	PUNCT	_	_	_	_	_	_
64	RAR	_	NOUN	_	Number=Sing	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	RAR	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	PML	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	RAR	_	PROPN	_	Number=Sing	_	_	_	_
13	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	parallelled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	increase	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	corresponding	_	VERB	_	Number=Sing	_	_	_	_
26	proteins	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Up	_	ADP	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	regulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	RAR	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	alpha	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	PML	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	RAR	_	PROPN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	IFN	_	PROPN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	strong	_	ADJ	_	Degree=Pos	_	_	_	_
25	potentiation	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	induction	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
34	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
35	markers	_	NOUN	_	Number=Plur	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	i.e.	_	X	_	_	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	colony	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
44	factor	_	NOUN	_	Number=Sing	_	_	_	_
45	receptor	_	NOUN	_	Number=Sing	_	_	_	_
46	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
49	alkaline	_	ADJ	_	Number=Sing	_	_	_	_
50	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IFN	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	have	_	VERB	_	VerbForm=Inf	_	_	_	_
10	any	_	DET	_	_	_	_	_	_
11	effects	_	NOUN	_	Number=Plur	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	retinoid	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
21	surface	_	NOUN	_	Number=Sing	_	_	_	_
22	markers	_	NOUN	_	Number=Plur	_	_	_	_
23	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	CD33	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IFN	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	increase	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	RAR	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	enhancing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	effect	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	retinoid	_	ADJ	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
24	markers	_	NOUN	_	Number=Plur	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	may	_	AUX	_	VerbForm=Fin	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	characteristic	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	PML	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	RAR	_	NOUN	_	Number=Sing	_	_	_	_
34	positive	_	ADJ	_	Degree=Pos	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	since	_	SCONJ	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	phenomena	_	NOUN	_	Number=Sing	_	_	_	_
40	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
41	not	_	PART	_	_	_	_	_	_
42	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	HL	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	60	_	NUM	_	NumType=Card	_	_	_	_
47	promyelocytes	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Interferons	_	NOUN	_	Number=Plur	_	_	_	_
2	as	_	ADV	_	_	_	_	_	_
3	well	_	ADV	_	Degree=Pos	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	retinoids	_	NOUN	_	Number=Plur	_	_	_	_
6	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	growth	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NB4	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	although	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	classes	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	compounds	_	NOUN	_	Number=Plur	_	_	_	_
19	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	significantly	_	ADV	_	_	_	_	_	_
22	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	terms	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	anti-proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	possible	_	ADJ	_	Degree=Pos	_	_	_	_
6	use	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	combinations	_	NOUN	_	Number=Plur	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	IFNs	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
13	acid	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	cyto	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	APL	_	NOUN	_	Number=Sing	_	_	_	_
22	patients	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300248	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	proenkephalin	_	NOUN	_	Number=Sing	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	accumulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	high	_	ADJ	_	Degree=Pos	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	neuropeptide	_	NOUN	_	Degree=Pos	_	_	_	_
12	enkephalin	_	NOUN	_	Number=Sing	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	correlate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	high	_	ADJ	_	Degree=Pos	_	_	_	_
17	levels	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	proenkephalin	_	ADJ	_	Number=Sing	_	_	_	_
20	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	basis	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	changes	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	proenkephalin	_	NOUN	_	Number=Sing	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	GGGGACGTCCCC	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	named	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	B2	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	similar	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	sequence	_	NOUN	_	Number=Sing	_	_	_	_
20	GGGGACTTTCC	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	NOUN	_	Number=Sing	_	_	_	_
36	B.	_	PROPN	_	Number=Sing	_	_	_	_
37	Activation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	T	_	PROPN	_	Number=Sing	_	_	_	_
40	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
41	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	NF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kappa	_	NOUN	_	Number=Sing	_	_	_	_
46	B	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	like	_	ADJ	_	Degree=Pos	_	_	_	_
49	binding	_	VERB	_	Number=Sing	_	_	_	_
50	activity	_	NOUN	_	Number=Sing	_	_	_	_
51	to	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	B2	_	PROPN	_	Number=Sing	_	_	_	_
54	site	_	NOUN	_	Number=Sing	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	concomitant	_	ADJ	_	Number=Sing	_	_	_	_
57	with	_	ADP	_	_	_	_	_	_
58	activation	_	NOUN	_	Number=Sing	_	_	_	_
59	of	_	ADP	_	_	_	_	_	_
60	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
61	proenkephalin	_	NOUN	_	Number=Sing	_	_	_	_
62	promoter	_	NOUN	_	Number=Sing	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	at	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	B2	_	PROPN	_	Number=Sing	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	abolish	_	VERB	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	purified	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
3	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	p50s	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	DNA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	subunit	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	PROPN	_	Number=Sing	_	_	_	_
19	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	B2	_	NOUN	_	Number=Sing	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	proenkephalin	_	NOUN	_	Number=Sing	_	_	_	_
25	relatively	_	ADV	_	_	_	_	_	_
26	better	_	ADJ	_	Degree=Cmp	_	_	_	_
27	than	_	SCONJ	_	_	_	_	_	_
28	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	heterotetramer	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	two	_	NUM	_	NumType=Card	_	_	_	_
33	p65s	_	NOUN	_	Number=Plur	_	_	_	_
34	plus	_	CCONJ	_	_	_	_	_	_
35	two	_	NUM	_	NumType=Card	_	_	_	_
36	p50s	_	NOUN	_	Number=Plur	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	form	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	factor	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	proenkephalin	_	ADJ	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	PROPN	_	Number=Sing	_	_	_	_
21	B.	_	PROPN	_	Number=Sing	_	_	_	_
22	However	_	ADV	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	as	_	SCONJ	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	PROPN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	through	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	B2	_	NOUN	_	Number=Sing	_	_	_	_
38	site	_	NOUN	_	Number=Sing	_	_	_	_
39	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	T	_	PROPN	_	Number=Sing	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	specific	_	ADJ	_	Degree=Pos	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	yet	_	CCONJ	_	_	_	_	_	_
45	another	_	DET	_	_	_	_	_	_
46	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	specific	_	ADJ	_	Degree=Pos	_	_	_	_
49	factor	_	NOUN	_	Number=Sing	_	_	_	_
50	which	_	PRON	_	PronType=Rel	_	_	_	_
51	synergizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
52	with	_	ADP	_	_	_	_	_	_
53	NF	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	kappa	_	NOUN	_	Number=Sing	_	_	_	_
56	B	_	PROPN	_	Number=Sing	_	_	_	_
57	should	_	AUX	_	VerbForm=Fin	_	_	_	_
58	be	_	AUX	_	VerbForm=Inf	_	_	_	_
59	considered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300253	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	hydrophobic	_	ADJ	_	Degree=Pos	_	_	_	_
3	domain	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
6	+-	_	PUNCT	_	_	_	_	_	_
7	modulating	_	ADJ	_	VerbForm=Ger	_	_	_	_
8	cyclophilin	_	NOUN	_	Number=Sing	_	_	_	_
9	ligand	_	NOUN	_	Number=Sing	_	_	_	_
10	modulates	_	NOUN	_	Number=Plur	_	_	_	_
11	calcium	_	NOUN	_	Number=Sing	_	_	_	_
12	influx	_	NOUN	_	Number=Sing	_	_	_	_
13	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
2	+-	_	PUNCT	_	_	_	_	_	_
3	modulating	_	VERB	_	Number=Sing	_	_	_	_
4	cyclophilin	_	NOUN	_	Number=Sing	_	_	_	_
5	ligand	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	CAML	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	originally	_	ADV	_	_	_	_	_	_
11	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	cyclophilin	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
20	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	rise	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
29	calcium	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	thus	_	ADV	_	_	_	_	_	_
32	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	factors	_	NOUN	_	Number=Plur	_	_	_	_
35	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	early	_	ADJ	_	Degree=Pos	_	_	_	_
39	immune	_	ADJ	_	Degree=Pos	_	_	_	_
40	response	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	structure	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	function	_	NOUN	_	Number=Sing	_	_	_	_
8	analysis	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	CAML	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	two	_	NUM	_	NumType=Card	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	CAML	_	PROPN	_	Number=Sing	_	_	_	_
22	's	_	PART	_	_	_	_	_	_
23	putative	_	ADJ	_	Degree=Pos	_	_	_	_
24	membrane	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	spanning	_	VERB	_	VerbForm=Ger	_	_	_	_
27	domains	_	NOUN	_	Number=Plur	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	modulation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
37	calcium	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	hydrophobic	_	ADJ	_	Degree=Pos	_	_	_	_
6	C-	_	NOUN	_	Number=Sing	_	_	_	_
7	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
8	tail	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	CAML	_	NOUN	_	Number=Sing	_	_	_	_
11	forms	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	effector	_	NOUN	_	Number=Sing	_	_	_	_
14	domain	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	thus	_	ADV	_	_	_	_	_	_
17	implicating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	N	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
22	hydrophilic	_	ADJ	_	Degree=Pos	_	_	_	_
23	domain	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	role	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	define	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	novel	_	NOUN	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	motif	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	DET	_	PronType=Rel	_	_	_	_
9	functions	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
12	calcium	_	NOUN	_	Number=Sing	_	_	_	_
13	signaling	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300255	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	interleukin	_	ADJ	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1beta	_	NOUN	_	Number=Sing	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	Barr	_	PROPN	_	Number=Sing	_	_	_	_
11	virus	_	NOUN	_	Number=Sing	_	_	_	_
12	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	number	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	latent	_	ADJ	_	Degree=Pos	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	via	_	ADP	_	_	_	_	_	_
19	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	interaction	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	RBP	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Barr	_	PROPN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EBV	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	infects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	B	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	outgrowth	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	immortalised	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	lymphoblastoid	_	NOUN	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	lines	_	NOUN	_	Number=Plur	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	LCLs	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	through	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	use	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	staining	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1beta	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1beta	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	LCLs	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	influence	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	individual	_	ADJ	_	Degree=Pos	_	_	_	_
31	latent	_	ADJ	_	Number=Sing	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	on	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1beta	_	PROPN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	RT	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	PCR	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1beta	_	PROPN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	up	_	ADV	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	EBV	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	LCLs	_	NOUN	_	Number=Plur	_	_	_	_
21	as	_	ADV	_	_	_	_	_	_
22	well	_	ADV	_	Degree=Pos	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	group	_	NOUN	_	Number=Sing	_	_	_	_
26	III	_	PROPN	_	NumType=Card	_	_	_	_
27	Burkitt	_	PROPN	_	Number=Sing	_	_	_	_
28	's	_	PART	_	_	_	_	_	_
29	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	BL	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	lines	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	group	_	NOUN	_	Number=Sing	_	_	_	_
39	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
40	BL	_	AUX	_	Number=Sing	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	lines	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	up	_	ADP	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1beta	_	PROPN	_	Number=Sing	_	_	_	_
9	message	_	NOUN	_	Number=Sing	_	_	_	_
10	could	_	AUX	_	VerbForm=Fin	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	latent	_	ADJ	_	Degree=Pos	_	_	_	_
16	membrane	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	EBV	_	PROPN	_	Number=Sing	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	3	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	4	_	NUM	_	NumType=Card	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	6	_	NUM	_	NumType=Card	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EMSAs	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	300	_	NUM	_	NumType=Card	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1beta	_	PROPN	_	Number=Sing	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	binding	_	NOUN	_	Number=Sing	_	_	_	_
34	site	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	functional	_	ADJ	_	Degree=Pos	_	_	_	_
39	RBP	_	NOUN	_	Number=Sing	_	_	_	_
40	binding	_	NOUN	_	Number=Sing	_	_	_	_
41	site	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	RBP	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	could	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	addition	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	EBV	_	PROPN	_	Number=Sing	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	3	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	6	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	displace	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	RBP	_	NOUN	_	Number=Sing	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	recognition	_	NOUN	_	Number=Sing	_	_	_	_
29	sequence	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	removing	_	VERB	_	VerbForm=Ger	_	_	_	_
32	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
33	repression	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	allowing	_	VERB	_	VerbForm=Ger	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	group	_	NOUN	_	Number=Sing	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	BL	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
8	low	_	ADJ	_	Degree=Pos	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	only	_	ADV	_	_	_	_	_	_
16	RBP	_	NOUN	_	Number=Sing	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	EMSAs	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	whereas	_	SCONJ	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	could	_	AUX	_	VerbForm=Fin	_	_	_	_
29	be	_	AUX	_	VerbForm=Inf	_	_	_	_
30	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	EBV	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	lines	_	NOUN	_	Number=Plur	_	_	_	_
38	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
39	high	_	ADJ	_	Degree=Pos	_	_	_	_
40	levels	_	NOUN	_	Number=Plur	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	NF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	latent	_	ADJ	_	Degree=Pos	_	_	_	_
8	membrane	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	capable	_	ADJ	_	Degree=Pos	_	_	_	_
22	of	_	SCONJ	_	_	_	_	_	_
23	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1beta	_	PROPN	_	Number=Sing	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	EBV	_	PROPN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	up	_	ADV	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1beta	_	PROPN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	possibly	_	ADV	_	_	_	_	_	_
16	by	_	SCONJ	_	_	_	_	_	_
17	using	_	VERB	_	VerbForm=Ger	_	_	_	_
18	RBP	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	both	_	DET	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1998	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300256	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Essential	_	ADJ	_	Degree=Pos	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
5	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	intrapulmonary	_	ADJ	_	Degree=Pos	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Acute	_	ADJ	_	Degree=Pos	_	_	_	_
2	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	injury	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	rat	_	NOUN	_	Number=Sing	_	_	_	_
6	lung	_	NOUN	_	Number=Sing	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	deposition	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
12	G	_	NOUN	_	Number=Sing	_	_	_	_
13	immune	_	ADJ	_	Number=Sing	_	_	_	_
14	complexes	_	NOUN	_	Number=Plur	_	_	_	_
15	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	chemokines	_	NOUN	_	Number=Plur	_	_	_	_
21	as	_	ADV	_	_	_	_	_	_
22	well	_	ADV	_	Degree=Pos	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	little	_	ADJ	_	Degree=Pos	_	_	_	_
4	direct	_	ADJ	_	Degree=Pos	_	_	_	_
5	evidence	_	NOUN	_	Number=Sing	_	_	_	_
6	regarding	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
11	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	events	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	rat	_	NOUN	_	Number=Sing	_	_	_	_
7	lungs	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	depleted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
12	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	airway	_	NOUN	_	Number=Sing	_	_	_	_
15	instillation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	liposome	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	encapsulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	dichloromethylene	_	NOUN	_	Number=Sing	_	_	_	_
21	diphosphonate	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	procedures	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	greatly	_	ADV	_	_	_	_	_	_
6	reduced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	number	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	retrievable	_	ADJ	_	Degree=Pos	_	_	_	_
11	alveolar	_	NOUN	_	Degree=Pos	_	_	_	_
12	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	lung	_	ADJ	_	Number=Sing	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	model	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	bronchoalveolar	_	NOUN	_	Number=Sing	_	_	_	_
5	lavage	_	NOUN	_	Number=Sing	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	tumor	_	NOUN	_	Number=Sing	_	_	_	_
9	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	CXC	_	PROPN	_	Number=Sing	_	_	_	_
21	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
24	inflammatory	_	NOUN	_	Degree=Pos	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	substantially	_	ADV	_	_	_	_	_	_
31	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	parallel	_	ADJ	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	lung	_	ADJ	_	Number=Sing	_	_	_	_
8	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
9	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
10	molecule	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
13	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
14	molecule	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	greatly	_	ADV	_	_	_	_	_	_
20	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	intrapulmonary	_	ADJ	_	Degree=Pos	_	_	_	_
23	instillation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	phosphonate	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
28	liposomes	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Neutrophil	_	PROPN	_	Degree=Pos	_	_	_	_
2	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	development	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	lung	_	NOUN	_	Number=Sing	_	_	_	_
7	injury	_	NOUN	_	Number=Sing	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	substantially	_	ADV	_	_	_	_	_	_
11	diminished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Lung	_	NOUN	_	Number=Sing	_	_	_	_
2	instillation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
9	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	depleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	rats	_	NOUN	_	Number=Plur	_	_	_	_
13	restored	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	whole	_	ADJ	_	Degree=Pos	_	_	_	_
22	lung	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	model	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	initial	_	ADJ	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	occurs	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
20	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	ensuing	_	VERB	_	Degree=Pos	_	_	_	_
24	production	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	TNF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	may	_	AUX	_	VerbForm=Fin	_	_	_	_
30	propagate	_	VERB	_	VerbForm=Inf	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	other	_	ADJ	_	Degree=Pos	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	types	_	NOUN	_	Number=Plur	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	lung	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300258	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Suppression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	MHC	_	PROPN	_	Number=Sing	_	_	_	_
4	class	_	NOUN	_	Number=Sing	_	_	_	_
5	II	_	NUM	_	NumType=Card	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	class	_	NOUN	_	Number=Sing	_	_	_	_
10	II	_	NUM	_	NumType=Card	_	_	_	_
11	trans	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	activator	_	NOUN	_	Number=Sing	_	_	_	_
14	constructs	_	NOUN	_	Number=Plur	_	_	_	_
15	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	N	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	terminal	_	NOUN	_	Number=Sing	_	_	_	_
20	domain	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	class	_	NOUN	_	Number=Sing	_	_	_	_
3	II	_	NUM	_	Number=Sing	_	_	_	_
4	trans	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activator	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	bi	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	multi-functional	_	ADJ	_	Degree=Pos	_	_	_	_
16	domain	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	critical	_	ADJ	_	Degree=Pos	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	MHC	_	PROPN	_	Number=Sing	_	_	_	_
28	class	_	NOUN	_	Number=Sing	_	_	_	_
29	II	_	PROPN	_	Number=Sing	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	DET	_	_	_	_	_	_
4	removal	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	N-terminal	_	PROPN	_	Number=Sing	_	_	_	_
8	151	_	NUM	_	NumType=Card	_	_	_	_
9	amino	_	NOUN	_	Number=Sing	_	_	_	_
10	acids	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	encompassing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	all	_	DET	_	_	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	acidic	_	ADJ	_	Degree=Pos	_	_	_	_
17	domain	_	NOUN	_	Number=Sing	_	_	_	_
18	but	_	CCONJ	_	_	_	_	_	_
19	leaving	_	VERB	_	VerbForm=Ger	_	_	_	_
20	intact	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	proline	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	serine	_	NOUN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	threonine-rich	_	ADJ	_	Number=Sing	_	_	_	_
27	domain	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	results	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	mutant	_	NOUN	_	Number=Sing	_	_	_	_
33	protein	_	NOUN	_	Number=Sing	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	potent	_	ADJ	_	Degree=Pos	_	_	_	_
36	suppressive	_	ADJ	_	Degree=Pos	_	_	_	_
37	properties	_	NOUN	_	Number=Plur	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	MHC	_	PROPN	_	Number=Sing	_	_	_	_
40	class	_	NOUN	_	Number=Sing	_	_	_	_
41	II	_	NUM	_	NumType=Card	_	_	_	_
42	expression	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	stably	_	ADV	_	_	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	transiently	_	ADV	_	_	_	_	_	_
6	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
9	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
10	constructs	_	NOUN	_	Number=Plur	_	_	_	_
11	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	up	_	ADP	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	99	_	NUM	_	NumType=Card	_	_	_	_
15	%	_	SYM	_	Number=Sing	_	_	_	_
16	suppression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	MHC	_	PROPN	_	Number=Sing	_	_	_	_
19	class	_	NOUN	_	Number=Sing	_	_	_	_
20	II	_	NUM	_	NumType=Card	_	_	_	_
21	antigen	_	NOUN	_	Number=Sing	_	_	_	_
22	induction	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	IFN	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	gamma	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	suppression	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	HLA	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	DRA	_	PROPN	_	Number=Sing	_	_	_	_
34	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
7	line	_	NOUN	_	Number=Sing	_	_	_	_
8	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	up	_	ADP	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	89	_	NUM	_	NumType=Card	_	_	_	_
13	%	_	SYM	_	Number=Sing	_	_	_	_
14	reduction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
17	MHC	_	PROPN	_	Number=Sing	_	_	_	_
18	class	_	NOUN	_	Number=Sing	_	_	_	_
19	II	_	NUM	_	NumType=Card	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	within	_	ADP	_	_	_	_	_	_
22	5	_	NUM	_	NumType=Card	_	_	_	_
23	days	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	suppression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	HLA	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	DRA	_	PROPN	_	Number=Sing	_	_	_	_
30	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
31	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300264	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	jun	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	fos	_	ADP	_	_	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
14	colony	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
3	colony	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	M	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CSF	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	growth	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	signaling	_	NOUN	_	Number=Sing	_	_	_	_
5	events	_	NOUN	_	Number=Plur	_	_	_	_
6	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	effects	_	NOUN	_	Number=Plur	_	_	_	_
10	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	M	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	CSF	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	potential	_	ADJ	_	Degree=Pos	_	_	_	_
14	signaling	_	NOUN	_	Number=Sing	_	_	_	_
15	pathways	_	NOUN	_	Number=Plur	_	_	_	_
16	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	jun	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	fos	_	ADP	_	_	_	_	_	_
23	early	_	ADJ	_	Degree=Pos	_	_	_	_
24	response	_	NOUN	_	Number=Sing	_	_	_	_
25	genes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Low	_	ADJ	_	Degree=Pos	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	jun	_	NOUN	_	Number=Sing	_	_	_	_
7	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	SCONJ	_	_	_	_	_	_
11	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
14	blood	_	NOUN	_	Number=Sing	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	10	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	units	_	NOUN	_	Number=Plur	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	ml	_	NOUN	_	Number=Sing	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	recombinant	_	NOUN	_	Number=Sing	_	_	_	_
15	M	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	CSF	_	PROPN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	transient	_	ADJ	_	Degree=Pos	_	_	_	_
24	increases	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	c	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	jun	_	NOUN	_	Number=Sing	_	_	_	_
29	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
30	levels	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	run	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
8	stability	_	NOUN	_	Number=Sing	_	_	_	_
9	studies	_	NOUN	_	Number=Plur	_	_	_	_
10	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	M	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	CSF	_	PROPN	_	Number=Sing	_	_	_	_
15	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	increase	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	rate	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	prolongation	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	half	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	life	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	c	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	jun	_	NOUN	_	Number=Sing	_	_	_	_
37	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	M-CSF	_	NOUN	_	Number=Sing	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	jun	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	B	_	NOUN	_	Degree=Pos	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	although	_	SCONJ	_	_	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	prolonged	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	c	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	jun	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	M	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	CSF	_	NOUN	_	Number=Sing	_	_	_	_
8	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
10	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	control	_	NOUN	_	Number=Sing	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Maximal	_	ADJ	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	followed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	fos	_	NOUN	_	Number=Sing	_	_	_	_
14	-B	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	M	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	CSF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	fos	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	related	_	ADJ	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	fra-1	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	delayed	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	both	_	CCONJ	_	_	_	_	_	_
25	c	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	fos	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	fos	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	M	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CSF	_	NOUN	_	Number=Sing	_	_	_	_
11	treatment	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	differential	_	ADJ	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
19	members	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	jun	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	fos	_	NOUN	_	Number=Sing	_	_	_	_
25	family	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
31	genes	_	NOUN	_	Number=Plur	_	_	_	_
32	could	_	AUX	_	VerbForm=Fin	_	_	_	_
33	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
36	signaling	_	NOUN	_	Number=Sing	_	_	_	_
37	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
38	that	_	PRON	_	PronType=Rel	_	_	_	_
39	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	specific	_	ADJ	_	Degree=Pos	_	_	_	_
42	program	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
45	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300280	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Uncoupling	_	NOUN	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	HS1	_	NOUN	_	Number=Sing	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	:	_	PUNCT	_	_	_	_	_	_
21	differential	_	NOUN	_	Degree=Pos	_	_	_	_
22	signaling	_	NOUN	_	Number=Sing	_	_	_	_
23	through	_	ADP	_	_	_	_	_	_
24	CD3	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	receptors	_	NOUN	_	Number=Plur	_	_	_	_
29	CD2	_	PROPN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	CD28	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	CD3	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CD2	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	CD28	_	PROPN	_	Number=Sing	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	functionally	_	ADV	_	_	_	_	_	_
9	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
10	receptors	_	NOUN	_	Number=Plur	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Engagement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	any	_	DET	_	_	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	receptors	_	NOUN	_	Number=Plur	_	_	_	_
7	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
10	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
11	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	shared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	group	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	signaling	_	NOUN	_	Number=Sing	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	including	_	VERB	_	VerbForm=Ger	_	_	_	_
22	Vav	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	p85	_	PROPN	_	Number=Sing	_	_	_	_
27	phosphoinositide	_	NOUN	_	Number=Sing	_	_	_	_
28	3	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	Src	_	PROPN	_	Number=Sing	_	_	_	_
35	family	_	NOUN	_	Number=Sing	_	_	_	_
36	kinases	_	NOUN	_	Number=Plur	_	_	_	_
37	Lck	_	PROPN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	Fyn.	_	PROPN	_	Number=Sing	_	_	_	_
40	Ligation	_	PROPN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	CD3	_	PROPN	_	Number=Sing	_	_	_	_
43	also	_	ADV	_	_	_	_	_	_
44	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
47	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	HS1	_	NOUN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
52	75	_	NUM	_	NumType=Card	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	kDa	_	NOUN	_	Number=Sing	_	_	_	_
55	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
56	cell	_	NOUN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	specific	_	ADJ	_	Degree=Pos	_	_	_	_
59	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
60	signaling	_	NOUN	_	Number=Sing	_	_	_	_
61	protein	_	NOUN	_	Number=Sing	_	_	_	_
62	of	_	ADP	_	_	_	_	_	_
63	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
64	function	_	NOUN	_	Number=Sing	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	changes	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	HS1	_	PROPN	_	Number=Sing	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	after	_	ADP	_	_	_	_	_	_
9	differential	_	ADJ	_	Degree=Pos	_	_	_	_
10	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	CD3	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	CD2	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	CD28	_	PROPN	_	Number=Sing	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	elucidate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	T	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	further	_	ADV	_	_	_	_	_	_
28	delineate	_	VERB	_	VerbForm=Inf	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	signaling	_	NOUN	_	Number=Sing	_	_	_	_
31	pathways	_	NOUN	_	Number=Plur	_	_	_	_
32	recruited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
35	receptors	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Unlike	_	ADP	_	_	_	_	_	_
2	ligation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	CD3	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	anti-CD28	_	PROPN	_	Degree=Pos	_	_	_	_
9	mAb	_	NOUN	_	Number=Sing	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	CHO	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	CD28	_	PROPN	_	Number=Sing	_	_	_	_
16	ligands	_	NOUN	_	Number=Plur	_	_	_	_
17	CD80	_	PROPN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	CD86	_	PROPN	_	Number=Sing	_	_	_	_
20	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	tyrosine	_	NOUN	_	VerbForm=Inf	_	_	_	_
25	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	HS1	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
30	T	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	HS1	_	PROPN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
12	pairs	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	anti-CD2	_	ADJ	_	Degree=Pos	_	_	_	_
15	mAbs	_	NOUN	_	Number=Plur	_	_	_	_
16	capable	_	ADJ	_	Degree=Pos	_	_	_	_
17	of	_	SCONJ	_	_	_	_	_	_
18	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Costimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	through	_	ADP	_	_	_	_	_	_
3	CD28	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	CD2	_	PROPN	_	Number=Sing	_	_	_	_
8	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	CD3	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	HS1	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	NOUN	_	Number=Sing	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	CD3	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	HSI	_	PROPN	_	Number=Sing	_	_	_	_
10	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	upon	_	ADP	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	Src	_	PROPN	_	Number=Sing	_	_	_	_
17	family	_	NOUN	_	Number=Sing	_	_	_	_
18	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
19	kinase	_	NOUN	_	Number=Sing	_	_	_	_
20	Lck	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
24	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
25	CD45	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	require	_	VERB	_	VerbForm=Inf	_	_	_	_
30	MEK1	_	PROPN	_	Number=Sing	_	_	_	_
31	kinase	_	NOUN	_	Number=Sing	_	_	_	_
32	activity	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	protein	_	NOUN	_	Number=Sing	_	_	_	_
39	kinase	_	NOUN	_	Number=Sing	_	_	_	_
40	C	_	NOUN	_	Number=Sing	_	_	_	_
41	activation	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	although	_	SCONJ	_	_	_	_	_	_
4	CD3	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	CD28	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	CD2	_	PROPN	_	Number=Sing	_	_	_	_
10	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	many	_	ADJ	_	Degree=Pos	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	same	_	ADJ	_	Degree=Pos	_	_	_	_
15	signaling	_	NOUN	_	Number=Sing	_	_	_	_
16	molecules	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
19	differed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	capacity	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	HSI	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HS1	_	PROPN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
15	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300283	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cytokine	_	PROPN	_	Number=Sing	_	_	_	_
2	rescue	_	NOUN	_	Number=Sing	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	through	_	ADP	_	_	_	_	_	_
13	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	DEX	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
12	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	mature	_	ADJ	_	Degree=Pos	_	_	_	_
18	Th	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	lines	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	induction	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	death	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	prevented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	specific	_	ADJ	_	Degree=Pos	_	_	_	_
33	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	namely	_	ADV	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	IL	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	2	_	NUM	_	NumType=Card	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	by	_	ADP	_	_	_	_	_	_
46	IL	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	4	_	NUM	_	NumType=Card	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	cells	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	differential	_	NOUN	_	Degree=Pos	_	_	_	_
7	rescue	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	Th	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	level	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	DEX	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	both	_	DET	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	types	_	NOUN	_	Number=Plur	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	DEX	_	PROPN	_	Number=Sing	_	_	_	_
17	treatment	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	DEX	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	mediated	_	VERB	_	Degree=Pos	_	_	_	_
7	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
8	induction	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	completely	_	ADV	_	_	_	_	_	_
11	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	not	_	ADV	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	while	_	SCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	reverse	_	ADJ	_	Degree=Pos	_	_	_	_
30	profile	_	NOUN	_	Number=Sing	_	_	_	_
31	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
32	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	Th2	_	DET	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	both	_	DET	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	types	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	DEX	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	also	_	ADV	_	_	_	_	_	_
18	rescues	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	DEX	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	although	_	SCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	rescue	_	NOUN	_	Number=Sing	_	_	_	_
30	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	different	_	ADJ	_	Degree=Pos	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	Th1	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	Th2	_	DET	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	imply	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	need	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	maintain	_	VERB	_	VerbForm=Inf	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	certain	_	ADJ	_	Degree=Pos	_	_	_	_
12	level	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	order	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	survive	_	VERB	_	VerbForm=Inf	_	_	_	_
23	;	_	PUNCT	_	_	_	_	_	_
24	up	_	ADP	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	down	_	ADV	_	_	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	regulation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
32	NF	_	NOUN	_	Number=Sing	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	through	_	ADP	_	_	_	_	_	_
35	modulation	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
41	or	_	CCONJ	_	_	_	_	_	_
42	DEX	_	PROPN	_	Number=Sing	_	_	_	_
43	may	_	AUX	_	VerbForm=Fin	_	_	_	_
44	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	cell	_	NOUN	_	Number=Sing	_	_	_	_
47	survival	_	NOUN	_	Number=Sing	_	_	_	_
48	or	_	CCONJ	_	_	_	_	_	_
49	cell	_	NOUN	_	Number=Sing	_	_	_	_
50	death	_	NOUN	_	Number=Sing	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	respectively	_	ADV	_	_	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300291	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tissue	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	rabbit	_	NOUN	_	Number=Sing	_	_	_	_
8	15	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	lipoxygenase	_	NOUN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	silencer	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	15	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	lipoxygenase	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	lox	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	tissue	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	manner	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	predominantly	_	ADV	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	also	_	ADV	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	airway	_	NOUN	_	Degree=Pos	_	_	_	_
26	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	report	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	'	_	PUNCT	_	_	_	_	_	_
10	flanking	_	VERB	_	VerbForm=Ger	_	_	_	_
11	DNA	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	15	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	lox	_	NOUN	_	Degree=Pos	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	sequences	_	NOUN	_	Number=Plur	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	down	_	ADV	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	variety	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	non-erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	lines	_	NOUN	_	Number=Plur	_	_	_	_
33	but	_	CCONJ	_	_	_	_	_	_
34	not	_	ADV	_	_	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	two	_	NUM	_	NumType=Card	_	_	_	_
37	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	lines	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	element	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	'	_	PUNCT	_	_	_	_	_	_
9	silencer	_	NOUN	_	Number=Sing	_	_	_	_
10	'	_	PUNCT	_	_	_	_	_	_
11	since	_	ADP	_	_	_	_	_	_
12	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
13	functions	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	orientations	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	main	_	ADJ	_	Degree=Pos	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	silencer	_	NOUN	_	Number=Sing	_	_	_	_
7	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
9	mapped	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
13	900	_	NUM	_	NumType=Card	_	_	_	_
14	bp	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	5	_	NUM	_	NumType=Card	_	_	_	_
17	'	_	PUNCT	_	_	_	_	_	_
18	flanking	_	VERB	_	VerbForm=Ger	_	_	_	_
19	DNA	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	nine	_	NUM	_	NumType=Card	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	sites	_	NOUN	_	Number=Plur	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	present	_	VERB	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	non-erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	not	_	ADV	_	_	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	binding	_	NOUN	_	Degree=Pos	_	_	_	_
3	sites	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	similar	_	ADJ	_	Degree=Pos	_	_	_	_
6	sequences	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
9	copies	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	binding	_	VERB	_	Degree=Pos	_	_	_	_
13	sites	_	NOUN	_	Number=Plur	_	_	_	_
14	confer	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	tissue	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	down	_	ADP	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	regulation	_	NOUN	_	Number=Sing	_	_	_	_
21	when	_	ADV	_	PronType=Int	_	_	_	_
22	attached	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
26	lox	_	NOUN	_	Number=Sing	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	fragment	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	5	_	NUM	_	NumType=Card	_	_	_	_
3	'	_	PUNCT	_	_	_	_	_	_
4	flanking	_	VERB	_	VerbForm=Ger	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	cluster	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	three	_	NUM	_	NumType=Card	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	sites	_	NOUN	_	Number=Plur	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	GATA	_	PROPN	_	Number=Sing	_	_	_	_
17	family	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factors	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300292	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	appearance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	CD28	_	PROPN	_	Number=Sing	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	element	_	NOUN	_	Number=Sing	_	_	_	_
12	within	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
18	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	signaling	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	molecules	_	NOUN	_	Number=Plur	_	_	_	_
17	such	_	ADJ	_	Degree=Pos	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	CD28	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	critical	_	ADJ	_	Degree=Pos	_	_	_	_
19	control	_	NOUN	_	Number=Sing	_	_	_	_
20	point	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
6	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	functional	_	ADJ	_	Degree=Pos	_	_	_	_
9	motif	_	NOUN	_	Number=Sing	_	_	_	_
10	named	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	CD28	_	PROPN	_	Number=Sing	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	element	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	CD28RE	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	serves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	role	_	NOUN	_	Number=Sing	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	target	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	signals	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CD28RE	_	PROPN	_	Number=Sing	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	reveals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	similarity	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	consensus	_	NOUN	_	Number=Sing	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	motif	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CD28RE	_	PROPN	_	Number=Sing	_	_	_	_
6	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
13	mass	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	approximately	_	ADV	_	_	_	_	_	_
16	35	_	NUM	_	NumType=Card	_	_	_	_
17	kDa	_	NOUN	_	Number=Sing	_	_	_	_
18	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	mitogenic	_	ADJ	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	MATp35	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	that	_	PRON	_	PronType=Rel	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	clearly	_	ADV	_	_	_	_	_	_
35	different	_	ADJ	_	Degree=Pos	_	_	_	_
36	from	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
42	/	_	PUNCT	_	_	_	_	_	_
43	Rel	_	NOUN	_	Number=Sing	_	_	_	_
44	family	_	NOUN	_	Number=Sing	_	_	_	_
45	members	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	MATp35	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	depend	_	VERB	_	VerbForm=Inf	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	de	_	PROPN	_	Number=Sing	_	_	_	_
12	novo	_	PROPN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	received	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
25	combination	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	not	_	PART	_	_	_	_	_	_
32	necessarily	_	ADV	_	_	_	_	_	_
33	including	_	VERB	_	VerbForm=Ger	_	_	_	_
34	CD28	_	PROPN	_	Number=Sing	_	_	_	_
35	signaling	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Nonmitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
5	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	result	_	VERB	_	VerbForm=Inf	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	appearance	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	MATp35	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
6	combinations	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	signals	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	integrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	level	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	MATp35	_	PROPN	_	Number=Sing	_	_	_	_
21	induction	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
12	A	_	PROPN	_	Number=Sing	_	_	_	_
13	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	MATp35	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	appearance	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	MATp35	_	NOUN	_	Number=Sing	_	_	_	_
15	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	excellent	_	ADJ	_	Degree=Pos	_	_	_	_
17	correlation	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	production	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	unique	_	ADJ	_	Degree=Pos	_	_	_	_
28	characteristic	_	NOUN	_	Number=Sing	_	_	_	_
29	among	_	ADP	_	_	_	_	_	_
30	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
31	factors	_	NOUN	_	Number=Plur	_	_	_	_
32	implicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	control	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300298	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Id3	_	NOUN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	cycle	_	NOUN	_	Number=Sing	_	_	_	_
6	function	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	Cdk	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	functions	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	basic	_	ADJ	_	Degree=Pos	_	_	_	_
5	helix	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	loop	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	helix	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	bHLH	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	in	_	SCONJ	_	_	_	_	_	_
24	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
25	G1	_	PROPN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	cycle	_	NOUN	_	Number=Sing	_	_	_	_
28	arrest	_	NOUN	_	Number=Sing	_	_	_	_
29	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	negatively	_	ADV	_	_	_	_	_	_
31	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	members	_	NOUN	_	Number=Plur	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	Id	_	NOUN	_	Number=Sing	_	_	_	_
37	family	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	HLH	_	ADJ	_	Number=Sing	_	_	_	_
40	proteins	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	bHLH	_	ADJ	_	Degree=Pos	_	_	_	_
3	antagonists	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	during	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
9	signalling	_	NOUN	_	VerbForm=Ger	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
14	function	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	by	_	SCONJ	_	_	_	_	_	_
16	sequestering	_	VERB	_	VerbForm=Ger	_	_	_	_
17	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	bHLH	_	NOUN	_	Number=Sing	_	_	_	_
19	targets	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
22	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	unable	_	ADJ	_	Degree=Pos	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	specific	_	ADJ	_	Degree=Pos	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	regulatory	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	E	_	NOUN	_	Number=Sing	_	_	_	_
34	box	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	sequences	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cyclin	_	PROPN	_	Number=Sing	_	_	_	_
4	E	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	Cdk2	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	cyclin	_	PROPN	_	Number=Sing	_	_	_	_
10	A	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Cdk2	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	single	_	ADJ	_	Degree=Pos	_	_	_	_
19	conserved	_	ADJ	_	Degree=Pos	_	_	_	_
20	serine	_	NOUN	_	Number=Sing	_	_	_	_
21	residue	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	Ser5	_	X	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	Id2	_	PROPN	_	Number=Sing	_	_	_	_
27	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
29	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
32	during	_	ADP	_	_	_	_	_	_
33	late	_	ADJ	_	Degree=Pos	_	_	_	_
34	G1	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	S	_	PROPN	_	Number=Sing	_	_	_	_
39	phase	_	NOUN	_	Number=Sing	_	_	_	_
40	transition	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	cell	_	NOUN	_	Number=Sing	_	_	_	_
44	cycle	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
48	neutralizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	function	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	Id2	_	NOUN	_	Number=Sing	_	_	_	_
53	in	_	SCONJ	_	_	_	_	_	_
54	abrogating	_	VERB	_	VerbForm=Ger	_	_	_	_
55	E-box	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
58	bHLH	_	NOUN	_	Degree=Pos	_	_	_	_
59	homo	_	NOUN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	or	_	CCONJ	_	_	_	_	_	_
62	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
63	complex	_	ADJ	_	Number=Sing	_	_	_	_
64	formation	_	NOUN	_	Number=Sing	_	_	_	_
65	in	_	ADP	_	_	_	_	_	_
66	vitro	_	PROPN	_	Number=Sing	_	_	_	_
67	(	_	PUNCT	_	_	_	_	_	_
68	E.	_	PROPN	_	Number=Sing	_	_	_	_
69	Hara	_	PROPN	_	Number=Sing	_	_	_	_
70	,	_	PUNCT	_	_	_	_	_	_
71	M.Hall	_	PROPN	_	Number=Sing	_	_	_	_
72	,	_	PUNCT	_	_	_	_	_	_
73	and	_	CCONJ	_	_	_	_	_	_
74	G.	_	PROPN	_	Number=Sing	_	_	_	_
75	Peters	_	PROPN	_	Number=Sing	_	_	_	_
76	,	_	PUNCT	_	_	_	_	_	_
77	EMBO	_	PROPN	_	Number=Sing	_	_	_	_
78	J.16:332-342	_	NUM	_	Number=Sing	_	_	_	_
79	,	_	PUNCT	_	_	_	_	_	_
80	1997	_	NUM	_	NumType=Card	_	_	_	_
81	)	_	PUNCT	_	_	_	_	_	_
82	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	analogous	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	cycle	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	Id3	_	NOUN	_	Number=Sing	_	_	_	_
15	alters	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	specificity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	Id3	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	SCONJ	_	_	_	_	_	_
21	abrogating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	E-box	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	bHLH	_	NOUN	_	Number=Sing	_	_	_	_
27	homo	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
31	complex	_	ADJ	_	Degree=Pos	_	_	_	_
32	formation	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	vitro	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	E-box	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
39	reporter	_	NOUN	_	Number=Sing	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	function	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	vivo	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	wild	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	Id3	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	Id3	_	NOUN	_	Number=Sing	_	_	_	_
12	Asp5	_	NOUN	_	Number=Sing	_	_	_	_
13	mutant	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	mimicking	_	VERB	_	VerbForm=Ger	_	_	_	_
16	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	unable	_	ADJ	_	Degree=Pos	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	cycle	_	NOUN	_	Number=Sing	_	_	_	_
24	S	_	PART	_	_	_	_	_	_
25	phase	_	NOUN	_	Number=Sing	_	_	_	_
26	entry	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	whereas	_	SCONJ	_	_	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	Id3	_	NOUN	_	Number=Sing	_	_	_	_
34	Ala5	_	NOUN	_	Number=Sing	_	_	_	_
35	mutant	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	ablating	_	VERB	_	VerbForm=Ger	_	_	_	_
38	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	displays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	activity	_	NOUN	_	Number=Sing	_	_	_	_
43	significantly	_	ADV	_	_	_	_	_	_
44	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
45	than	_	ADP	_	_	_	_	_	_
46	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	wild	_	ADJ	_	Degree=Pos	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	type	_	NOUN	_	Number=Sing	_	_	_	_
51	Id3	_	NOUN	_	Number=Sing	_	_	_	_
52	protein	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Cdk2	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	therefore	_	ADV	_	_	_	_	_	_
6	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	switch	_	NOUN	_	Number=Sing	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	late	_	ADJ	_	Degree=Pos	_	_	_	_
11	G1	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	S	_	PROPN	_	Number=Sing	_	_	_	_
16	phase	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	both	_	DET	_	_	_	_	_	_
19	nullifies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	early	_	ADJ	_	Degree=Pos	_	_	_	_
22	G1	_	PROPN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	cycle	_	NOUN	_	Number=Sing	_	_	_	_
25	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
26	function	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	Id3	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	modulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
32	target	_	NOUN	_	Number=Sing	_	_	_	_
33	bHLH	_	NOUN	_	Number=Sing	_	_	_	_
34	specificity	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	ability	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Id3	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	cycle	_	NOUN	_	Number=Sing	_	_	_	_
14	S	_	PART	_	_	_	_	_	_
15	phase	_	NOUN	_	Number=Sing	_	_	_	_
16	entry	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	simply	_	ADV	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	function	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	ability	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	bHLH	_	ADJ	_	Degree=Pos	_	_	_	_
28	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	establish	_	VERB	_	VerbForm=Inf	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	biologically	_	ADV	_	_	_	_	_	_
37	important	_	ADJ	_	Degree=Pos	_	_	_	_
38	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
39	through	_	ADP	_	_	_	_	_	_
40	which	_	PRON	_	PronType=Rel	_	_	_	_
41	Cdk2	_	NOUN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	Id	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	bHLH	_	ADJ	_	Degree=Pos	_	_	_	_
46	functions	_	NOUN	_	Number=Plur	_	_	_	_
47	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
48	integrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	coordination	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	cell	_	NOUN	_	Number=Sing	_	_	_	_
54	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
55	and	_	CCONJ	_	_	_	_	_	_
56	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002100	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	lymphoblastoid	_	ADJ	_	Number=Sing	_	_	_	_
14	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	line	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	wild	_	ADJ	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	type	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	CD4	_	PROPN	_	Number=Sing	_	_	_	_
25	receptors	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	presence	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	CD4	_	PROPN	_	Number=Sing	_	_	_	_
11	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
12	tail	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	critical	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	J.Corbeil	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	M.	_	PROPN	_	Number=Sing	_	_	_	_
29	Tremblay	_	PROPN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	D.D.Richman	_	PROPN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	J.Exp.Med.183:39-48	_	PROPN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	1996	_	NUM	_	NumType=Card	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	pursued	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	investigation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	CD4	_	PROPN	_	Number=Sing	_	_	_	_
12	transduction	_	NOUN	_	Number=Sing	_	_	_	_
13	pathway	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	do	_	VERB	_	VerbForm=Inf	_	_	_	_
3	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	wild	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
10	forms	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	CD4	_	PROPN	_	Number=Sing	_	_	_	_
14	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
15	tail	_	NOUN	_	Number=Sing	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	stably	_	ADV	_	_	_	_	_	_
18	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	lymphoblastoid	_	NOUN	_	Number=Sing	_	_	_	_
22	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	A2.01	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Apoptosis	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	prevented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	when	_	ADV	_	PronType=Int	_	_	_	_
5	CD4	_	PROPN	_	Number=Sing	_	_	_	_
6	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	at	_	ADP	_	_	_	_	_	_
8	residue	_	NOUN	_	Number=Sing	_	_	_	_
9	402	_	NUM	_	NumType=Card	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	;	_	PUNCT	_	_	_	_	_	_
13	however	_	ADV	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	receptors	_	NOUN	_	Number=Plur	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	associate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	p56	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	lck	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	at	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	dicysteine	_	NOUN	_	Degree=Pos	_	_	_	_
33	motif	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	at	_	ADP	_	_	_	_	_	_
37	residue	_	NOUN	_	Number=Sing	_	_	_	_
38	418	_	NUM	_	NumType=Card	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	but	_	CCONJ	_	_	_	_	_	_
41	which	_	PRON	_	PronType=Int	_	_	_	_
42	conserved	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
44	domains	_	NOUN	_	Number=Plur	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
48	tail	_	NOUN	_	Number=Sing	_	_	_	_
49	underwent	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
50	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
51	like	_	ADP	_	_	_	_	_	_
52	wild	_	ADJ	_	Degree=Pos	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	type	_	NOUN	_	Number=Sing	_	_	_	_
55	CD4	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	differences	_	NOUN	_	Number=Plur	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	wild	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	receptors	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	related	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	levels	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	p56	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	lck	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Initial	_	ADJ	_	Degree=Pos	_	_	_	_
2	signaling	_	NOUN	_	Number=Sing	_	_	_	_
3	through	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	CD4	_	PROPN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	played	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	major	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	sensitization	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	undergo	_	VERB	_	VerbForm=Inf	_	_	_	_
22	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Incubation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HIV	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
9	antibody	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	MAb	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	13B8	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	CD4	_	PROPN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	region	_	NOUN	_	Number=Sing	_	_	_	_
24	critical	_	ADJ	_	Degree=Pos	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	dimerization	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	prevented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
33	without	_	SCONJ	_	_	_	_	_	_
34	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
35	HIV	_	NOUN	_	Number=Sing	_	_	_	_
36	replication	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
5	process	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	related	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	Fas	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Fas	_	NOUN	_	Number=Sing	_	_	_	_
13	ligand	_	NOUN	_	Number=Sing	_	_	_	_
14	interaction	_	NOUN	_	Number=Sing	_	_	_	_
15	;	_	PUNCT	_	_	_	_	_	_
16	however	_	ADV	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	antagonistic	_	ADJ	_	Degree=Pos	_	_	_	_
20	anti-Fas	_	NOUN	_	Number=Sing	_	_	_	_
21	MAb	_	PROPN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	ZB	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	4	_	NUM	_	NumType=Card	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	HIV	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	without	_	SCONJ	_	_	_	_	_	_
35	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
36	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	uninfected	_	ADJ	_	Degree=Pos	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CD4	_	PROPN	_	Number=Sing	_	_	_	_
6	signaling	_	VERB	_	Number=Sing	_	_	_	_
7	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
15	independent	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Fas	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	Fas	_	NOUN	_	Number=Sing	_	_	_	_
20	ligand	_	NOUN	_	Number=Sing	_	_	_	_
21	interaction	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	require	_	VERB	_	VerbForm=Inf	_	_	_	_
26	p56	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	lck	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	signaling	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	may	_	AUX	_	VerbForm=Fin	_	_	_	_
34	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	critical	_	ADJ	_	Degree=Pos	_	_	_	_
37	region	_	NOUN	_	Number=Sing	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	CD4	_	PROPN	_	Number=Sing	_	_	_	_
40	dimerization	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002101	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	elk	_	NOUN	_	Number=Plur	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Potential	_	ADJ	_	Degree=Pos	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
6	intronic	_	ADJ	_	Degree=Pos	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	elk	_	NOUN	_	Number=Plur	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	elk	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	mapped	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	start	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	elk	_	NOUN	_	Number=Plur	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
24	phage	_	NOUN	_	Number=Sing	_	_	_	_
25	clones	_	NOUN	_	Number=Plur	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	extensive	_	ADJ	_	Degree=Pos	_	_	_	_
29	upstream	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
32	sequences	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	TATA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	like	_	ADJ	_	Degree=Pos	_	_	_	_
5	motif	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	immediately	_	ADV	_	_	_	_	_	_
9	upstream	_	ADV	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
13	start	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	analyses	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	DNA	_	NOUN	_	Number=Sing	_	_	_	_
5	fragments	_	NOUN	_	Number=Plur	_	_	_	_
6	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	TATA	_	PROPN	_	Number=Sing	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	identification	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	DNase	_	NOUN	_	Number=Sing	_	_	_	_
16	I	_	PRON	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
19	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	HS	_	PROPN	_	Number=Sing	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	close	_	ADJ	_	Degree=Pos	_	_	_	_
27	proximity	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	TATA	_	PROPN	_	Number=Sing	_	_	_	_
31	box	_	NOUN	_	Number=Sing	_	_	_	_
32	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	that	_	SCONJ	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	TATA	_	PROPN	_	Number=Sing	_	_	_	_
37	motif	_	NOUN	_	Number=Sing	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	important	_	ADJ	_	Degree=Pos	_	_	_	_
40	for	_	ADP	_	_	_	_	_	_
41	elk	_	NOUN	_	Number=Plur	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	1	_	NUM	_	NumType=Card	_	_	_	_
44	transcription	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	vivo	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Sequences	_	NOUN	_	Number=Plur	_	_	_	_
2	upstream	_	ADV	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	TATA	_	PROPN	_	Number=Sing	_	_	_	_
8	box	_	NOUN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	elk	_	NOUN	_	Number=Plur	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
4	site	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	HS	_	PROPN	_	Number=Sing	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
14	intron	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	pre-monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	Elk	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	only	_	ADV	_	_	_	_	_	_
25	when	_	ADV	_	PronType=Int	_	_	_	_
26	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	variety	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	other	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	types	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	display	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
13	Elk	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	HS	_	PROPN	_	Number=Sing	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	exist	_	VERB	_	VerbForm=Inf	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	elk	_	NOUN	_	Number=Plur	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	presence	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	HS	_	PROPN	_	Number=Sing	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Egr	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	serum	_	NOUN	_	Number=Sing	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
13	specifically	_	ADV	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	intronic	_	ADJ	_	Degree=Pos	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	265	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	+	_	SYM	_	_	_	_	_	_
23	448	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	respectively	_	ADV	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	Egr	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
13	significantly	_	ADV	_	_	_	_	_	_
14	before	_	ADP	_	_	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	elk	_	NOUN	_	Number=Plur	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
23	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	Egr	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	important	_	ADJ	_	Degree=Pos	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	regulation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	elk	_	NOUN	_	Number=Plur	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
40	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002102	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	platelets	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	platelets	_	NOUN	_	Number=Plur	_	_	_	_
5	tether	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	activate	_	VERB	_	Degree=Pos	_	_	_	_
8	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
9	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	potential	_	ADJ	_	Degree=Pos	_	_	_	_
5	relevance	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	acute	_	ADJ	_	Degree=Pos	_	_	_	_
11	myocardial	_	ADJ	_	Degree=Pos	_	_	_	_
12	infarction	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	AMI	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
18	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
20	induction	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	platelet	_	NOUN	_	Number=Sing	_	_	_	_
25	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	occurrence	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	platelet	_	NOUN	_	Number=Sing	_	_	_	_
33	conjugates	_	NOUN	_	Number=Plur	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	patients	_	NOUN	_	Number=Sing	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	AMI	_	PROPN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	AND	_	CCONJ	_	_	_	_	_	_
3	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	obtained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
4	venous	_	ADJ	_	Degree=Pos	_	_	_	_
5	blood	_	NOUN	_	Number=Sing	_	_	_	_
6	samples	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	20	_	NUM	_	NumType=Card	_	_	_	_
9	patients	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	AMI	_	PROPN	_	Number=Sing	_	_	_	_
12	before	_	ADV	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	daily	_	ADV	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	5	_	NUM	_	NumType=Card	_	_	_	_
17	days	_	NOUN	_	Number=Plur	_	_	_	_
18	after	_	ADP	_	_	_	_	_	_
19	direct	_	ADJ	_	Degree=Pos	_	_	_	_
20	percutaneous	_	ADJ	_	Degree=Pos	_	_	_	_
21	transluminal	_	ADJ	_	Number=Sing	_	_	_	_
22	coronary	_	ADJ	_	Number=Sing	_	_	_	_
23	angioplasty	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	PTCA	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	20	_	NUM	_	NumType=Card	_	_	_	_
30	patients	_	NOUN	_	Number=Plur	_	_	_	_
31	undergoing	_	VERB	_	VerbForm=Ger	_	_	_	_
32	elective	_	ADJ	_	Degree=Pos	_	_	_	_
33	PTCA	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Throughout	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	period	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	CD41	_	PROPN	_	Number=Sing	_	_	_	_
7	immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	flow	_	VERB	_	Number=Sing	_	_	_	_
12	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	platelet	_	NOUN	_	Number=Sing	_	_	_	_
19	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	patients	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	AMI	_	PROPN	_	Number=Sing	_	_	_	_
24	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	control	_	NOUN	_	Number=Sing	_	_	_	_
27	patients	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	mean	_	VERB	_	VerbForm=Inf	_	_	_	_
30	+/-	_	SYM	_	_	_	_	_	_
31	SE	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	fluorescence	_	NOUN	_	Number=Sing	_	_	_	_
34	[	_	PUNCT	_	_	_	_	_	_
35	channels	_	NOUN	_	Number=Plur	_	_	_	_
36	]	_	PUNCT	_	_	_	_	_	_
37	before	_	ADP	_	_	_	_	_	_
38	PTCA	_	NOUN	_	Number=Sing	_	_	_	_
39	:	_	PUNCT	_	_	_	_	_	_
40	77	_	NUM	_	NumType=Card	_	_	_	_
41	+/-	_	SYM	_	_	_	_	_	_
42	16	_	NUM	_	NumType=Card	_	_	_	_
43	versus	_	ADP	_	_	_	_	_	_
44	35	_	NUM	_	NumType=Card	_	_	_	_
45	+/-	_	SYM	_	_	_	_	_	_

1	9	_	NUM	_	NumType=Card	_	_	_	_
2	;	_	PUNCT	_	_	_	_	_	_
3	P	_	NOUN	_	Number=Sing	_	_	_	_
4	=	_	SYM	_	_	_	_	_	_
5	.003	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	fixed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	platelets	_	NOUN	_	Number=Plur	_	_	_	_
9	bound	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Within	_	ADP	_	_	_	_	_	_
2	2	_	NUM	_	NumType=Card	_	_	_	_
3	hours	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
6	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	beta	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	8	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
25	chemoattractant	_	NOUN	_	Number=Sing	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	MCP	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	unfractionated	_	ADJ	_	Degree=Pos	_	_	_	_
34	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	4	_	NUM	_	NumType=Card	_	_	_	_
3	hours	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	beta	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	8	_	NUM	_	NumType=Card	_	_	_	_
13	concentration	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	free	_	ADJ	_	Degree=Pos	_	_	_	_
19	supernatant	_	NOUN	_	Number=Sing	_	_	_	_
20	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	268	_	NUM	_	NumType=Card	_	_	_	_
24	+/-	_	SYM	_	_	_	_	_	_
25	36	_	NUM	_	NumType=Card	_	_	_	_
26	%	_	SYM	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	210	_	NUM	_	NumType=Card	_	_	_	_
29	+/-	_	SYM	_	_	_	_	_	_
30	7	_	NUM	_	NumType=Card	_	_	_	_
31	%	_	SYM	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	respectively	_	ADV	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
37	MCP	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	content	_	NOUN	_	Number=Sing	_	_	_	_
41	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
42	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	170	_	NUM	_	NumType=Card	_	_	_	_
45	+/-	_	SYM	_	_	_	_	_	_
46	8%.	_	NUM	_	Number=Sing	_	_	_	_
47	Addition	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	platelets	_	NOUN	_	Number=Plur	_	_	_	_
51	to	_	PART	_	_	_	_	_	_
52	adherent	_	VERB	_	Degree=Pos	_	_	_	_
53	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
54	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
55	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
56	similar	_	ADJ	_	Degree=Pos	_	_	_	_
57	effect	_	NOUN	_	Number=Sing	_	_	_	_
58	and	_	CCONJ	_	_	_	_	_	_
59	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
60	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
61	with	_	ADP	_	_	_	_	_	_
62	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
63	factor	_	NOUN	_	Number=Sing	_	_	_	_
64	-	_	PUNCT	_	_	_	_	_	_
65	kappa	_	NOUN	_	Number=Sing	_	_	_	_
66	B	_	NOUN	_	Number=Sing	_	_	_	_
67	activation	_	NOUN	_	Number=Sing	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	binding	_	VERB	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	anti-P	_	ADJ	_	Degree=Pos	_	_	_	_
6	selectin	_	NOUN	_	Number=Sing	_	_	_	_
7	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
8	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	effect	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	platelets	_	NOUN	_	Number=Plur	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	patients	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	AMI	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	platelet	_	NOUN	_	Number=Sing	_	_	_	_
9	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	platelets	_	NOUN	_	Number=Plur	_	_	_	_
5	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	beta	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	8	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	MCP	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	platelet	_	NOUN	_	Number=Sing	_	_	_	_
8	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
9	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	responses	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	AMI	_	PROPN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002116	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Paternal	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	WT1	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Wilms	_	PROPN	_	Number=Plur	_	_	_	_
3	'	_	PART	_	_	_	_	_	_
4	tumor	_	NOUN	_	Number=Sing	_	_	_	_
5	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	WT1	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	previously	_	ADV	_	_	_	_	_	_
12	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	as	_	SCONJ	_	_	_	_	_	_
14	being	_	AUX	_	VerbForm=Ger	_	_	_	_
15	imprinted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	frequent	_	ADJ	_	Degree=Pos	_	_	_	_
19	maternal	_	ADJ	_	Degree=Pos	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	placentae	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	fetal	_	ADJ	_	Number=Sing	_	_	_	_
26	brains	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	allele	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	WT1	_	PROPN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	cultured	_	VERB	_	Degree=Pos	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	15	_	NUM	_	NumType=Card	_	_	_	_
16	individuals	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Seven	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	15	_	NUM	_	NumType=Card	_	_	_	_
4	fibroblast	_	NOUN	_	Degree=Pos	_	_	_	_
5	lines	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	heterozygous	_	ADJ	_	Degree=Pos	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	polymorphic	_	ADJ	_	Degree=Pos	_	_	_	_
10	alleles	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	patterns	_	NOUN	_	Number=Plur	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	variable	_	ADJ	_	Degree=Pos	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	i.e.	_	X	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	equal	_	ADJ	_	Degree=Pos	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	unequal	_	ADJ	_	Degree=Pos	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	monoallelic	_	ADJ	_	Degree=Pos	_	_	_	_
26	paternal	_	ADJ	_	Degree=Pos	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	three	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	two	_	NUM	_	NumType=Card	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	two	_	NUM	_	NumType=Card	_	_	_	_
34	cases	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	respectively	_	ADV	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Exclusive	_	ADJ	_	Degree=Pos	_	_	_	_
2	paternal	_	ADJ	_	Degree=Pos	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	WT1	_	PROPN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	non-cultured	_	ADJ	_	Degree=Pos	_	_	_	_
11	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	latter	_	ADJ	_	Degree=Pos	_	_	_	_
16	two	_	NUM	_	NumType=Card	_	_	_	_
17	individuals	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	allele	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	profiles	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	other	_	ADJ	_	Degree=Pos	_	_	_	_
9	imprinted	_	VERB	_	Degree=Pos	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	IGF2	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	H19	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
19	11	_	NUM	_	NumType=Card	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	constant	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	other	_	ADJ	_	Degree=Pos	_	_	_	_
28	tissues	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	unexpected	_	ADJ	_	Degree=Pos	_	_	_	_
3	observations	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	paternal	_	ADJ	_	Number=Sing	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	biallelic	_	ADJ	_	Degree=Pos	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	WT1	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	together	_	ADV	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	previous	_	ADJ	_	Degree=Pos	_	_	_	_
20	findings	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	maternal	_	ADJ	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	biallelic	_	ADJ	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	placentae	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	brains	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	that	_	SCONJ	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	allele	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	specific	_	ADJ	_	Degree=Pos	_	_	_	_
37	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
38	system	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	WT1	_	PROPN	_	Number=Sing	_	_	_	_
41	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	unique	_	ADJ	_	Degree=Pos	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	may	_	AUX	_	VerbForm=Fin	_	_	_	_
45	be	_	AUX	_	VerbForm=Inf	_	_	_	_
46	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
47	by	_	ADP	_	_	_	_	_	_
48	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
49	putative	_	ADJ	_	Degree=Pos	_	_	_	_
50	tissue	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	individual	_	ADJ	_	Degree=Pos	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	specific	_	ADJ	_	Degree=Pos	_	_	_	_
56	modifier	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002117	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	primary	_	ADJ	_	Degree=Pos	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	T-lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	through	_	ADP	_	_	_	_	_	_
7	CD2	_	PROPN	_	Number=Sing	_	_	_	_
8	plus	_	CCONJ	_	_	_	_	_	_
9	CD28	_	PROPN	_	Number=Sing	_	_	_	_
10	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
11	molecules	_	NOUN	_	Number=Plur	_	_	_	_
12	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	long	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	term	_	NOUN	_	Number=Sing	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B.	_	PROPN	_	Number=Sing	_	_	_	_
23	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	highly	_	ADV	_	_	_	_	_	_
26	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
29	via	_	ADP	_	_	_	_	_	_
30	CD2	_	PROPN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	CD28	_	PROPN	_	Number=Sing	_	_	_	_
33	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
34	molecules	_	NOUN	_	Number=Plur	_	_	_	_
35	induces	_	NOUN	_	Number=Plur	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	maintains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	more	_	ADJ	_	Degree=Cmp	_	_	_	_
41	than	_	ADP	_	_	_	_	_	_
42	3	_	NUM	_	NumType=Card	_	_	_	_
43	weeks	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	potent	_	NOUN	_	Number=Sing	_	_	_	_
3	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	require	_	VERB	_	VerbForm=Inf	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	accessory	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Long	_	ADV	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	lasting	_	VERB	_	VerbForm=Ger	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	receptivity	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	high	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	level	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	alpha	_	PROPN	_	Number=Sing	_	_	_	_
23	chain	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2R	_	NUM	_	Number=Sing	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	that	_	PRON	_	PronType=Rel	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	at	_	ADP	_	_	_	_	_	_
35	both	_	CCONJ	_	_	_	_	_	_
36	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
39	levels	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Increase	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2R	_	NUM	_	Number=Sing	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	consensus	_	NOUN	_	Number=Sing	_	_	_	_
24	sequence	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	5'-	_	ADJ	_	_	_	_	_	_
28	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
29	region	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2R	_	NOUN	_	Number=Sing	_	_	_	_
35	alpha	_	NOUN	_	Number=Sing	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	dissect	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	basis	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	unusually	_	ADV	_	_	_	_	_	_
9	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2R	_	NOUN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	binding	_	VERB	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	radiolabeled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2R	_	NOUN	_	Number=Sing	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	kappa	_	NOUN	_	Number=Sing	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	specific	_	ADJ	_	Degree=Pos	_	_	_	_
38	oligonucleotide	_	ADJ	_	Number=Sing	_	_	_	_
39	probe	_	NOUN	_	Number=Sing	_	_	_	_
40	during	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	time	_	NOUN	_	Number=Sing	_	_	_	_
43	course	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	CD2	_	NOUN	_	Number=Sing	_	_	_	_
46	+	_	SYM	_	_	_	_	_	_
47	CD28	_	PROPN	_	Number=Sing	_	_	_	_
48	activation	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Resting	_	VERB	_	VerbForm=Ger	_	_	_	_
2	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	extracts	_	NOUN	_	Number=Plur	_	_	_	_
5	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	KBF1	_	NUM	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	p50	_	NOUN	_	Number=Sing	_	_	_	_
9	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	new	_	ADJ	_	Degree=Pos	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	complexes	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	PROPN	_	Number=Sing	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	p50-p65	_	NUM	_	NumType=Card	_	_	_	_
19	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	putative	_	ADJ	_	Degree=Pos	_	_	_	_
22	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
23	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	p65	_	NOUN	_	Number=Sing	_	_	_	_
28	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
3	complexes	_	NOUN	_	Number=Plur	_	_	_	_
4	persisted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	at	_	ADV	_	_	_	_	_	_
7	least	_	ADV	_	Degree=Sup	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	weeks	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	relative	_	ADJ	_	Degree=Pos	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	very	_	ADV	_	_	_	_	_	_
6	similar	_	ADJ	_	Degree=Pos	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	duration	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	parallel	_	ADJ	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	CD2	_	PROPN	_	Number=Sing	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_
6	CD28	_	PROPN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	triggered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	significant	_	ADJ	_	Degree=Pos	_	_	_	_
11	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
12	thiol	_	NOUN	_	Number=Sing	_	_	_	_
13	decrease	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	oxygen	_	ADJ	_	Degree=Pos	_	_	_	_
18	radicals	_	NOUN	_	Number=Plur	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	involved	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
24	pathway	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
27	molecules	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	micromolar	_	ADJ	_	Degree=Pos	_	_	_	_
4	amounts	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	pyrrolidine	_	NOUN	_	Number=Sing	_	_	_	_
7	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
11	radical	_	ADJ	_	Degree=Pos	_	_	_	_
12	scavenger	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	efficiently	_	ADV	_	_	_	_	_	_
15	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	appearance	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	T-lymphocytes	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	also	_	ADV	_	_	_	_	_	_
28	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	secretion	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2R	_	NUM	_	NumType=Card	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	surface	_	NOUN	_	Number=Sing	_	_	_	_
40	expression	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
44	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	important	_	ADJ	_	Degree=Pos	_	_	_	_
14	role	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	long	_	ADJ	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	term	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	primary	_	ADJ	_	Degree=Pos	_	_	_	_
23	T-lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	via	_	ADP	_	_	_	_	_	_
25	CD2	_	PROPN	_	Number=Sing	_	_	_	_
26	+	_	SYM	_	_	_	_	_	_
27	CD28	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002118	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Overproduction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NFKB2	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	lyt	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	10	_	NUM	_	NumType=Card	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	Tax	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	trans	_	NOUN	_	Number=Plur	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	via	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	signalling	_	NOUN	_	Number=Sing	_	_	_	_
31	pathway	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	epidemiological	_	ADJ	_	Degree=Pos	_	_	_	_
6	evidence	_	NOUN	_	Number=Sing	_	_	_	_
7	implicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	etiologic	_	ADJ	_	Degree=Pos	_	_	_	_
14	agent	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	adult	_	NOUN	_	Number=Sing	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	ATL	_	PROPN	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Tax	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	positive	_	ADJ	_	Degree=Pos	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	activator	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	gene	_	VERB	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	viral	_	ADJ	_	Degree=Pos	_	_	_	_
23	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	also	_	ADV	_	_	_	_	_	_
26	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	including	_	VERB	_	VerbForm=Ger	_	_	_	_
32	GM	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	CSF	_	PROPN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2R	_	PROPN	_	Number=Sing	_	_	_	_
39	alpha	_	PROPN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	2	_	NUM	_	NumType=Card	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	targets	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	trans	_	NOUN	_	Number=Plur	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	effects	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Tax	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	Rel	_	NOUN	_	Number=Sing	_	_	_	_
22	family	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factors	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	pleiotropic	_	ADJ	_	Degree=Pos	_	_	_	_
28	regulators	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	immunoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	cytokine	_	ADJ	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	viral	_	ADJ	_	Degree=Pos	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	NFKB2	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	lyt	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	10	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	c-Rel	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	infected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	Tax	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	together	_	ADV	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	account	_	NOUN	_	Number=Sing	_	_	_	_
33	for	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	majority	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappa	_	NOUN	_	Number=Sing	_	_	_	_
42	B	_	NOUN	_	Number=Sing	_	_	_	_
43	binding	_	NOUN	_	Number=Sing	_	_	_	_
44	activity	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	before	_	ADP	_	_	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	after	_	ADP	_	_	_	_	_	_
51	PMA	_	PROPN	_	Number=Sing	_	_	_	_
52	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Most	_	ADV	_	_	_	_	_	_
2	importantly	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	Tax	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	correlation	_	NOUN	_	Number=Sing	_	_	_	_
11	between	_	ADP	_	_	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NFKB2	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	p100	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	processing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	DNA	_	PROPN	_	Number=Sing	_	_	_	_
23	binding	_	VERB	_	Number=Sing	_	_	_	_
24	NFKB2	_	PROPN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	p52	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	form	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	induction	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	c	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	Rel	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	trans	_	NOUN	_	Number=Plur	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	NF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	kappa	_	NOUN	_	Number=Sing	_	_	_	_
44	B	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
47	gene	_	NOUN	_	Number=Sing	_	_	_	_
48	expression	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NFKB2	_	PROPN	_	Number=Sing	_	_	_	_
5	precursor	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	physically	_	ADV	_	_	_	_	_	_
8	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	Tax	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	infected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	NFKB2	_	PROPN	_	Number=Sing	_	_	_	_
5	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	processing	_	VERB	_	Number=Sing	_	_	_	_
8	allows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	continuous	_	ADJ	_	Degree=Pos	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	otherwise	_	ADV	_	_	_	_	_	_
15	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	conjunction	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	NFKB2	_	PROPN	_	Number=Sing	_	_	_	_
27	alters	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	signalling	_	NOUN	_	Number=Sing	_	_	_	_
34	pathway	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
39	transformation	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	T	_	PROPN	_	Number=Sing	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002124	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	lpr	_	PROPN	_	Number=Sing	_	_	_	_
11	CD4	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	CD8	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	results	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	novel	_	NOUN	_	Number=Sing	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	binding	_	NOUN	_	Degree=Pos	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inert	_	ADJ	_	Degree=Pos	_	_	_	_
3	quality	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	MRL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Ipr	_	PROPN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	Ipr	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	Ipr	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	peripheral	_	ADJ	_	Number=Sing	_	_	_	_
14	CD4	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	CD8	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	CD4	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	8	_	NUM	_	NumType=Card	_	_	_	_
22	-)	_	PUNCT	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	manifests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	primarily	_	ADV	_	_	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	inability	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	proliferate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	response	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	TCR	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
21	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Yet	_	CCONJ	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	same	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	early	_	ADJ	_	Degree=Pos	_	_	_	_
8	TCR	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
11	signaling	_	NOUN	_	Number=Sing	_	_	_	_
12	events	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	such	_	ADJ	_	Degree=Pos	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	generation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	inositol	_	NOUN	_	Degree=Pos	_	_	_	_
19	phosphates	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
23	calcium	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	display	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	constitutively	_	ADV	_	_	_	_	_	_
5	high	_	ADJ	_	Degree=Pos	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	p59fyn	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	CD3	_	PROPN	_	Number=Sing	_	_	_	_
11	zeta	_	NOUN	_	Number=Sing	_	_	_	_
12	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
13	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	generation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
5	messengers	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	normally	_	ADV	_	_	_	_	_	_
10	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
13	signaling	_	VERB	_	Number=Sing	_	_	_	_
14	that	_	DET	_	_	_	_	_	_
15	results	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	therefore	_	ADV	_	_	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	state	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	freshly	_	ADV	_	_	_	_	_	_
19	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	Ipr	_	PROPN	_	Number=Sing	_	_	_	_
23	CD4	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	SYM	_	_	_	_	_	_
25	8	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	normal	_	ADJ	_	Degree=Pos	_	_	_	_
33	T	_	NOUN	_	Number=Sing	_	_	_	_
34	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Levels	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	octamer	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	PROPN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	p50	_	NUM	_	Number=Sing	_	_	_	_
12	-	_	SYM	_	_	_	_	_	_
13	p65	_	NUM	_	Number=Sing	_	_	_	_
14	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	constitutively	_	ADV	_	_	_	_	_	_
25	elevated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	freshly	_	ADV	_	_	_	_	_	_
28	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	Ipr	_	PROPN	_	Number=Sing	_	_	_	_
30	CD4	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	SYM	_	_	_	_	_	_
32	8	_	NUM	_	NumType=Card	_	_	_	_
33	-	_	SYM	_	_	_	_	_	_
34	T	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	formation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transactivating	_	NOUN	_	Number=Sing	_	_	_	_
10	complex	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	AT	_	ADP	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	normal	_	ADJ	_	Degree=Pos	_	_	_	_
27	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	Ipr	_	PROPN	_	Number=Sing	_	_	_	_
30	CD4	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	8	_	NUM	_	NumType=Card	_	_	_	_
33	-	_	SYM	_	_	_	_	_	_
34	T	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Yet	_	CCONJ	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	AT	_	ADP	_	_	_	_	_	_
11	complex	_	NOUN	_	Number=Sing	_	_	_	_
12	never	_	ADV	_	_	_	_	_	_
13	reach	_	VERB	_	VerbForm=Inf	_	_	_	_
14	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
15	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	similarly	_	ADV	_	_	_	_	_	_
18	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	normal	_	ADJ	_	Degree=Pos	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	extracts	_	NOUN	_	Number=Plur	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	Ipr	_	PROPN	_	Number=Sing	_	_	_	_
7	CD4	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	8	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	T	_	NUM	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	display	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	high	_	ADJ	_	Degree=Pos	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	novel	_	NOUN	_	Number=Sing	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	at	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	AT	_	ADP	_	_	_	_	_	_
27	site	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	present	_	ADJ	_	Degree=Pos	_	_	_	_
32	at	_	ADP	_	_	_	_	_	_
33	much	_	ADV	_	_	_	_	_	_
34	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
35	levels	_	NOUN	_	Number=Plur	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	freshly	_	ADV	_	_	_	_	_	_
38	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	normal	_	ADJ	_	Degree=Pos	_	_	_	_
40	T	_	NOUN	_	Number=Sing	_	_	_	_
41	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	novel	_	NOUN	_	Number=Sing	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	AT	_	ADP	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	rapidly	_	ADV	_	_	_	_	_	_
19	down	_	ADV	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	regulated	_	VERB	_	Degree=Pos	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	normal	_	ADJ	_	Degree=Pos	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	persists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	at	_	ADP	_	_	_	_	_	_
30	high	_	ADJ	_	Degree=Pos	_	_	_	_
31	levels	_	NOUN	_	Number=Plur	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	Ipr	_	PROPN	_	Number=Sing	_	_	_	_
34	CD4	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	8	_	NUM	_	NumType=Card	_	_	_	_
37	-	_	SYM	_	_	_	_	_	_
38	T	_	NOUN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
4	at	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	AT	_	ADP	_	_	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	potential	_	ADJ	_	Degree=Pos	_	_	_	_
13	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	account	_	VERB	_	VerbForm=Inf	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	defect	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	Ipr	_	PROPN	_	Number=Sing	_	_	_	_
26	CD4	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	SYM	_	_	_	_	_	_
28	8	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	SYM	_	_	_	_	_	_
30	T	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002127	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	growth	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	CD8	_	NOUN	_	Number=Sing	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_

1	T	_	DET	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	prolymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
4	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	normal	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	receptor	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	2R	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	alpha	_	NOUN	_	Number=Sing	_	_	_	_
45	chain	_	NOUN	_	Number=Sing	_	_	_	_
46	gene	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	cell	_	NOUN	_	Number=Sing	_	_	_	_
50	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2R	_	NOUN	_	Number=Sing	_	_	_	_
12	signaling	_	VERB	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	growth	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	CD8	_	NOUN	_	Number=Sing	_	_	_	_
18	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	prolymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
4	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	PLL	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Flow	_	PROPN	_	Number=Sing	_	_	_	_
2	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
3	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	primary	_	ADJ	_	Degree=Pos	_	_	_	_
6	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	patient	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	CD8	_	NOUN	_	Number=Sing	_	_	_	_
13	+	_	SYM	_	_	_	_	_	_

1	T-PLL	_	ADV	_	_	_	_	_	_
2	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	Ralpha	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	beta	_	NOUN	_	Number=Sing	_	_	_	_
9	chains	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	increase	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	culture	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	exogeneous	_	ADJ	_	Degree=Pos	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	PROPN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	detect	_	VERB	_	VerbForm=Inf	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	act	_	VERB	_	VerbForm=Inf	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	paracrine	_	NOUN	_	Degree=Pos	_	_	_	_
22	manner	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	vivo	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	extracts	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
28	blot	_	NOUN	_	Number=Sing	_	_	_	_
29	analysis	_	NOUN	_	Number=Sing	_	_	_	_
30	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	abundance	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
40	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	NF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
45	components	_	NOUN	_	Number=Plur	_	_	_	_
46	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	KBF1	_	PROPN	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
51	cells	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	markedly	_	ADV	_	_	_	_	_	_
12	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	number	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	low	_	ADJ	_	Degree=Pos	_	_	_	_
17	affinity	_	NOUN	_	Number=Sing	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2Rs	_	NOUN	_	Number=Plur	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	without	_	ADP	_	_	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	effect	_	NOUN	_	Number=Sing	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	number	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	high	_	ADJ	_	Degree=Pos	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	affinity	_	NOUN	_	Number=Sing	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2Rs	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	capable	_	ADJ	_	Degree=Pos	_	_	_	_
10	of	_	SCONJ	_	_	_	_	_	_
11	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	primary	_	ADJ	_	Degree=Pos	_	_	_	_
21	CD8	_	NOUN	_	Number=Sing	_	_	_	_
22	+	_	SYM	_	_	_	_	_	_

1	T-PLL	_	NOUN	_	_	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	at	_	ADV	_	_	_	_	_	_
12	least	_	ADV	_	Degree=Sup	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	part	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	pretranslational	_	ADJ	_	Degree=Pos	_	_	_	_
19	level	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002129	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Impaired	_	ADJ	_	Degree=Pos	_	_	_	_
2	fetal	_	ADJ	_	Number=Sing	_	_	_	_
3	thymocyte	_	NOUN	_	Number=Sing	_	_	_	_
4	development	_	NOUN	_	Number=Sing	_	_	_	_
5	after	_	ADP	_	_	_	_	_	_
6	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
7	adenovirus	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
10	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	introduce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	new	_	ADJ	_	Degree=Pos	_	_	_	_
5	experimental	_	ADJ	_	Degree=Pos	_	_	_	_
6	system	_	NOUN	_	Number=Sing	_	_	_	_
7	combining	_	VERB	_	VerbForm=Ger	_	_	_	_
8	adenovirus	_	NOUN	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	transfer	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	fetal	_	VERB	_	Degree=Pos	_	_	_	_
15	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
16	organ	_	ADJ	_	Degree=Pos	_	_	_	_
17	culture	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	FTOC	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	system	_	NOUN	_	Number=Sing	_	_	_	_
3	allowed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	us	_	PRON	_	Case=Acc|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	efficiently	_	ADV	_	_	_	_	_	_
7	express	_	VERB	_	VerbForm=Inf	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	developing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
13	form	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	kappa	_	VERB	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	mut	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
29	kappa	_	VERB	_	Number=Sing	_	_	_	_
30	B	_	PROPN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	study	_	VERB	_	VerbForm=Inf	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	maturation	_	NOUN	_	Number=Sing	_	_	_	_
37	defects	_	NOUN	_	Number=Plur	_	_	_	_
38	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
39	when	_	ADV	_	PronType=Int	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappa	_	PROPN	_	Number=Sing	_	_	_	_
43	B	_	NOUN	_	Number=Sing	_	_	_	_
44	activation	_	NOUN	_	Number=Sing	_	_	_	_
45	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
46	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
47	during	_	ADP	_	_	_	_	_	_
48	fetal	_	ADJ	_	Number=Sing	_	_	_	_
49	development	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Fetal	_	ADJ	_	Degree=Pos	_	_	_	_
2	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	adenovirus	_	NOUN	_	Number=Sing	_	_	_	_
6	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	mut	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	kappa	_	VERB	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	develop	_	VERB	_	VerbForm=Inf	_	_	_	_
16	normally	_	ADV	_	_	_	_	_	_
17	until	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	CD44-CD25	_	NOUN	_	Number=Sing	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	CD4	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	CD8	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	double	_	ADJ	_	Degree=Pos	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	negative	_	ADJ	_	Degree=Pos	_	_	_	_
29	stage	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	while	_	SCONJ	_	_	_	_	_	_
32	production	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	more	_	ADV	_	_	_	_	_	_
35	mature	_	ADJ	_	Degree=Pos	_	_	_	_
36	double	_	ADJ	_	Degree=Pos	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	positive	_	ADJ	_	Degree=Pos	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	single	_	ADJ	_	Degree=Pos	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	positive	_	ADJ	_	Degree=Pos	_	_	_	_
43	populations	_	NOUN	_	Number=Plur	_	_	_	_
44	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
45	strongly	_	ADV	_	_	_	_	_	_
46	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Proliferation	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	as	_	SCONJ	_	_	_	_	_	_
4	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	percentage	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	cycle	_	NOUN	_	Number=Sing	_	_	_	_
12	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	normal	_	ADJ	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	as	_	SCONJ	_	_	_	_	_	_
16	did	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	TCR	_	PROPN	_	Number=Sing	_	_	_	_
23	beta-chain	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	much	_	ADV	_	_	_	_	_	_
6	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	FTOC	_	NOUN	_	Number=Sing	_	_	_	_
9	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	adenovirus	_	NOUN	_	Number=Sing	_	_	_	_
12	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	mut	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	VERB	_	Number=Sing	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	FTOC	_	PROPN	_	Number=Sing	_	_	_	_
21	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	control	_	NOUN	_	Number=Sing	_	_	_	_
25	virus	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	PROPN	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	SCONJ	_	_	_	_	_	_
17	ensuring	_	VERB	_	VerbForm=Ger	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	survival	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	early	_	ADJ	_	Degree=Pos	_	_	_	_
27	stages	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
30	development	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002140	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Positive	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	negative	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
9	colony	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	AML1	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	related	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
5	colony	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	GM	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	CSF	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	consensus	_	NOUN	_	Number=Sing	_	_	_	_
19	sequence	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	polyomavirus	_	NOUN	_	Number=Sing	_	_	_	_
23	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	which	_	PRON	_	PronType=Rel	_	_	_	_
35	consists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	beta	_	NOUN	_	Number=Sing	_	_	_	_
40	subunits	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	at	_	ADV	_	_	_	_	_	_
4	least	_	ADV	_	Degree=Sup	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	A	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	subunit	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	alpha	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mouse	_	NOUN	_	Number=Sing	_	_	_	_
5	homologue	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	AML1	_	PROPN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	breakpoints	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	t	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	8	_	NUM	_	NumType=Card	_	_	_	_
18	;	_	PUNCT	_	_	_	_	_	_
19	21	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	t	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	;	_	PUNCT	_	_	_	_	_	_
26	21	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
29	leukemias	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	alpha	_	PROPN	_	Number=Sing	_	_	_	_
4	A1	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	A	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	product	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	alpha	_	PROPN	_	Number=Sing	_	_	_	_
15	B1	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	alpha	_	PROPN	_	Number=Sing	_	_	_	_
18	B2	_	PROPN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	two	_	NUM	_	NumType=Card	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	isomers	_	NOUN	_	Number=Plur	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
29	effects	_	NOUN	_	Number=Plur	_	_	_	_
30	on	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	GM	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	CSF	_	NOUN	_	Number=Sing	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	PEBP2	_	PROPN	_	Number=Sing	_	_	_	_
2	alpha	_	NOUN	_	Number=Sing	_	_	_	_

1	A1	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	alpha	_	PROPN	_	Number=Sing	_	_	_	_
4	B1	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	alpha	_	PROPN	_	Number=Sing	_	_	_	_

1	B2	_	PROPN	_	Number=Sing	_	_	_	_
2	proteins	_	NOUN	_	Number=Plur	_	_	_	_
3	bound	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	within	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	mouse	_	NOUN	_	Number=Sing	_	_	_	_
10	GM	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	CSF	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	PEBP2	_	PROPN	_	Number=Sing	_	_	_	_
2	alpha	_	NOUN	_	Number=Sing	_	_	_	_

1	A1	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	alpha	_	PROPN	_	Number=Sing	_	_	_	_

1	B1	_	PROPN	_	Number=Sing	_	_	_	_
2	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	GM	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	CSF	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	reporter	_	NOUN	_	Number=Sing	_	_	_	_
14	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	12-O-tetradecanoylphorbol	_	PROPN	_	Number=Sing	_	_	_	_
19	13	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	acetate	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	Jurkat	_	ADJ	_	Number=Sing	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	alpha	_	PROPN	_	Number=Sing	_	_	_	_

1	B2	_	PROPN	_	Number=Sing	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_

1	Coexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	alpha	_	PROPN	_	Number=Sing	_	_	_	_
4	B1	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	alpha	_	PROPN	_	Number=Sing	_	_	_	_

1	B2	_	PROPN	_	Number=Sing	_	_	_	_
2	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	could	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	alpha	_	PROPN	_	Number=Sing	_	_	_	_
13	B1	_	PROPN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	alpha	_	PROPN	_	Number=Sing	_	_	_	_
16	B2	_	PROPN	_	Number=Sing	_	_	_	_
17	ratio	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	extract	_	NOUN	_	Number=Sing	_	_	_	_
4	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	s	_	X	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	cross	_	VERB	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	reacted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	antimouse	_	NOUN	_	Number=Sing	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_

1	A1	_	NOUN	_	Number=Sing	_	_	_	_
2	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	PROPN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	A	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	alpha	_	PROPN	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	AML1	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	beta	_	NOUN	_	Number=Sing	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	further	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	precise	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	GM	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	CSF	_	NOUN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	present	_	ADJ	_	Degree=Pos	_	_	_	_
23	findings	_	NOUN	_	Number=Plur	_	_	_	_
24	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	importance	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	relative	_	ADJ	_	Degree=Pos	_	_	_	_
30	ratio	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	different	_	ADJ	_	Degree=Pos	_	_	_	_
33	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
34	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
35	in	_	SCONJ	_	_	_	_	_	_
36	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	levels	_	NOUN	_	Number=Plur	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	promoter	_	NOUN	_	Number=Sing	_	_	_	_
42	activity	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002141	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	lysosomal	_	ADJ	_	Degree=Pos	_	_	_	_
5	acid	_	NOUN	_	Number=Sing	_	_	_	_
6	lipase	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	differentiating	_	ADJ	_	VerbForm=Ger	_	_	_	_
9	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	AP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	X	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_
21	Human	_	ADJ	_	Degree=Pos	_	_	_	_
22	lysosomal	_	NOUN	_	Number=Sing	_	_	_	_
23	acid	_	VERB	_	Number=Sing	_	_	_	_
24	lipase	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	LAL	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	hydrolase	_	NOUN	_	Number=Sing	_	_	_	_
31	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	cholesteryl	_	NOUN	_	Number=Sing	_	_	_	_
37	esters	_	NOUN	_	Number=Plur	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	triglycerides	_	NOUN	_	Number=Plur	_	_	_	_
40	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	from	_	ADP	_	_	_	_	_	_
42	plasma	_	NOUN	_	Number=Sing	_	_	_	_
43	lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	here	_	ADV	_	PronType=Dem	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	during	_	ADP	_	_	_	_	_	_
7	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	macrophage	_	VERB	_	Number=Sing	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	LAL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	C	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	type	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	increase	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	LAL	_	PROPN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	further	_	ADV	_	_	_	_	_	_
12	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	THP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	line	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	respect	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
24	regulation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
4	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	line	_	NOUN	_	Number=Sing	_	_	_	_
7	THP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	differentiates	_	VERB	_	Number=Plur	_	_	_	_
11	into	_	ADP	_	_	_	_	_	_
12	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	like	_	ADP	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	when	_	ADV	_	PronType=Int	_	_	_	_
17	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
20	esters	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	cis	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
9	elements	_	NOUN	_	Number=Plur	_	_	_	_
10	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	basal	_	ADJ	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
16	12	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	myristate	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	13	_	NUM	_	NumType=Card	_	_	_	_
21	acetate	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	PMA	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
31	performed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	deletion	_	NOUN	_	Number=Sing	_	_	_	_
33	analysis	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	reporter	_	NOUN	_	Number=Sing	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	assays	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	PMA	_	PROPN	_	Number=Sing	_	_	_	_
3	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
4	element	_	NOUN	_	Number=Sing	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	between	_	ADP	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	182	_	NUM	_	NumType=Card	_	_	_	_
11	bp	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	107	_	NUM	_	NumType=Card	_	_	_	_
15	bp	_	NOUN	_	Number=Sing	_	_	_	_
16	upstream	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	major	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	start	_	NOUN	_	Number=Sing	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	LAL	_	PROPN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	PMA	_	PROPN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	THP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Co	_	X	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	transfections	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	further	_	ADV	_	Degree=Cmp	_	_	_	_
14	emphasized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	important	_	ADJ	_	Degree=Pos	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	both	_	CCONJ	_	_	_	_	_	_
24	basal	_	ADJ	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	PMA	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	LAL	_	PROPN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	increase	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	lysosomal	_	ADJ	_	Degree=Pos	_	_	_	_
10	acid	_	NOUN	_	Number=Sing	_	_	_	_
11	lipase	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	LAL	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	THP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	concerted	_	ADJ	_	Degree=Pos	_	_	_	_
26	action	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	AP	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_
34	Document	_	NOUN	_	Number=Sing	_	_	_	_
35	003002142	_	NUM	_	NumType=Card	_	_	_	_
36	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
4	regulates	_	NOUN	_	Number=Plur	_	_	_	_

1	Fas	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	APO-1/CD95	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	TCR	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
9	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	maintenance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	lymphocyte	_	ADJ	_	Number=Sing	_	_	_	_
5	homeostasis	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	critical	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	normal	_	ADJ	_	Degree=Pos	_	_	_	_
16	immune	_	NOUN	_	Number=Sing	_	_	_	_
17	system	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
7	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
9	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	play	_	VERB	_	VerbForm=Inf	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	SCONJ	_	_	_	_	_	_
15	protecting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	against	_	ADP	_	_	_	_	_	_
18	death	_	NOUN	_	Number=Sing	_	_	_	_
19	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	TNF	_	PROPN	_	Number=Sing	_	_	_	_
22	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
23	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	here	_	ADV	_	PronType=Dem	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
29	also	_	ADV	_	_	_	_	_	_
30	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	role	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	SCONJ	_	_	_	_	_	_
34	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
35	Fas	_	NOUN	_	Number=Sing	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	APO	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1/CD95-mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
40	death	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	major	_	ADJ	_	Degree=Pos	_	_	_	_
44	pathway	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
47	T	_	NOUN	_	Number=Sing	_	_	_	_
48	cell	_	NOUN	_	Number=Sing	_	_	_	_
49	death	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Transfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	subunits	_	NOUN	_	Number=Plur	_	_	_	_
11	p50	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	p65	_	NUM	_	Number=Sing	_	_	_	_
14	confers	_	VERB	_	Number=Plur	_	_	_	_
15	resistance	_	NOUN	_	Number=Sing	_	_	_	_
16	against	_	ADP	_	_	_	_	_	_
17	Fas	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Reciprocally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
12	peptide	_	NOUN	_	Number=Sing	_	_	_	_
13	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
17	form	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	makes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	more	_	ADV	_	_	_	_	_	_
31	susceptible	_	ADJ	_	Degree=Pos	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	Fas	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
36	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
12	peptide	_	NOUN	_	Number=Sing	_	_	_	_
13	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
14	rendered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	hybridoma	_	NOUN	_	Number=Sing	_	_	_	_
19	more	_	ADV	_	_	_	_	_	_
20	susceptible	_	ADJ	_	Degree=Pos	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	TCR	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
25	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Correspondingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	transfection	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	p50	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	p65	_	NOUN	_	Number=Sing	_	_	_	_
8	provided	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	considerable	_	ADJ	_	Degree=Pos	_	_	_	_
10	protection	_	NOUN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	TCR	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	corroborated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	studies	_	NOUN	_	Number=Plur	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	Fas	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
11	death	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	primary	_	ADJ	_	Degree=Pos	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Concanavalin	_	PROPN	_	Number=Sing	_	_	_	_
2	A	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	cycling	_	NOUN	_	Number=Sing	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	blasts	_	NOUN	_	Number=Plur	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	mice	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
17	IkappaB	_	ADJ	_	Number=Sing	_	_	_	_
18	molecule	_	NOUN	_	Number=Sing	_	_	_	_
19	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	Fas	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	down	_	ADJ	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	regulation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
38	complexes	_	NOUN	_	Number=Plur	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
5	TNF	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	itself	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs|Reflex=Yes	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	positive	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulator	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	with	_	SCONJ	_	_	_	_	_	_
17	neutralizing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
19	renders	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	more	_	ADV	_	_	_	_	_	_
23	susceptible	_	ADJ	_	Degree=Pos	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	anti-Fas	_	ADJ	_	Degree=Pos	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
28	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	summary	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	compelling	_	ADJ	_	Degree=Pos	_	_	_	_
8	evidence	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	protects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	against	_	ADP	_	_	_	_	_	_
15	Fas	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	death	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	likely	_	ADJ	_	_	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	important	_	ADJ	_	Degree=Pos	_	_	_	_
26	regulator	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	T	_	PROPN	_	Number=Sing	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	homeostasis	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002145	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	response	_	NOUN	_	Number=Sing	_	_	_	_
6	element	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	alpha	_	PROPN	_	Number=Sing	_	_	_	_
15	chain	_	NOUN	_	Number=Sing	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	composite	_	ADJ	_	Degree=Pos	_	_	_	_
20	element	_	NOUN	_	Number=Sing	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	Elf	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	HMG	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	Y	_	X	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	GATA	_	PROPN	_	Number=Sing	_	_	_	_
38	family	_	NOUN	_	Number=Sing	_	_	_	_
39	protein	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	alpha	_	PROPN	_	Number=Sing	_	_	_	_
15	chain	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	potently	_	ADV	_	_	_	_	_	_
19	upregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	own	_	ADJ	_	Degree=Pos	_	_	_	_
23	ligand	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	characterize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	essential	_	ADJ	_	Degree=Pos	_	_	_	_
9	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	consensus	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	non-consensus	_	ADJ	_	Degree=Pos	_	_	_	_
21	GAS	_	NOUN	_	Number=Sing	_	_	_	_
22	motifs	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	two	_	NUM	_	NumType=Card	_	_	_	_
25	putative	_	ADJ	_	Degree=Pos	_	_	_	_
26	Ets	_	NOUN	_	Number=Plur	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	sites	_	NOUN	_	Number=Plur	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	EBS	_	PROPN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	one	_	NUM	_	NumType=Card	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	which	_	PRON	_	PronType=Rel	_	_	_	_
36	overlaps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	consensus	_	NOUN	_	Number=Sing	_	_	_	_
39	GAS	_	NOUN	_	Number=Sing	_	_	_	_
40	motif	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	GATA	_	NOUN	_	Number=Sing	_	_	_	_
45	motif	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	which	_	PRON	_	PronType=Rel	_	_	_	_
48	overlaps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	non-consensus	_	ADJ	_	Degree=Pos	_	_	_	_
51	GAS	_	NOUN	_	Number=Sing	_	_	_	_
52	motif	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	although	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	individual	_	ADJ	_	Degree=Pos	_	_	_	_
7	components	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	together	_	ADV	_	_	_	_	_	_
20	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
21	form	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	composite	_	ADJ	_	Degree=Pos	_	_	_	_
24	element	_	NOUN	_	Number=Sing	_	_	_	_
25	capable	_	ADJ	_	Degree=Pos	_	_	_	_
26	of	_	SCONJ	_	_	_	_	_	_
27	conferring	_	VERB	_	VerbForm=Ger	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Multiple	_	ADJ	_	Degree=Pos	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	including	_	VERB	_	VerbForm=Ger	_	_	_	_
4	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	Elf	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	HMG	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	Y	_	X	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	GATA	_	PROPN	_	Number=Sing	_	_	_	_
18	family	_	NOUN	_	Number=Sing	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	response	_	NOUN	_	Number=Sing	_	_	_	_
27	element	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	mutation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	any	_	DET	_	_	_	_	_	_
32	one	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
35	binding	_	NOUN	_	Degree=Pos	_	_	_	_
36	sites	_	NOUN	_	Number=Plur	_	_	_	_
37	diminishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	activity	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
42	element	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	unidentified	_	ADJ	_	Degree=Pos	_	_	_	_
3	Ets	_	PROPN	_	Number=Sing	_	_	_	_
4	family	_	NOUN	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	binds	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	EBS	_	PROPN	_	Number=Sing	_	_	_	_
10	overlapping	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	consensus	_	NOUN	_	Number=Sing	_	_	_	_
13	GAS	_	NOUN	_	Number=Sing	_	_	_	_
14	motif	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	negatively	_	ADV	_	_	_	_	_	_
19	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2R	_	NOUN	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2-induced	_	VERB	_	NumType=Card	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2R	_	NOUN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	complex	_	ADJ	_	Degree=Pos	_	_	_	_
13	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	sites	_	NOUN	_	Number=Plur	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	both	_	CCONJ	_	_	_	_	_	_
24	positive	_	ADJ	_	Degree=Pos	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	negative	_	ADJ	_	Degree=Pos	_	_	_	_
27	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002146	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Genomic	_	ADJ	_	Degree=Pos	_	_	_	_
2	organization	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	sequence	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	eotaxin	_	NOUN	_	Degree=Pos	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Eotaxin	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	eosinophil	_	ADJ	_	Number=Sing	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
9	assumed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	involved	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	eosinophilic	_	ADJ	_	Degree=Pos	_	_	_	_
15	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	diseases	_	NOUN	_	Number=Plur	_	_	_	_
17	such	_	ADJ	_	Degree=Pos	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	atopic	_	ADJ	_	Degree=Pos	_	_	_	_
20	dermatitis	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	allergic	_	ADJ	_	Degree=Pos	_	_	_	_
23	rhinitis	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	asthma	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	parasitic	_	ADJ	_	Degree=Pos	_	_	_	_
28	infections	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	stimulus	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	here	_	ADV	_	PronType=Dem	_	_	_	_
3	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
6	organisation	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	exons	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	132	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	112	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	542	_	NUM	_	NumType=Card	_	_	_	_
16	bp	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	introns	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	1211	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	378	_	NUM	_	NumType=Card	_	_	_	_
24	bp	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	sequence	_	NOUN	_	Number=Sing	_	_	_	_
28	including	_	VERB	_	VerbForm=Ger	_	_	_	_
29	3	_	NUM	_	NumType=Card	_	_	_	_
30	kb	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	DNA	_	NOUN	_	Number=Sing	_	_	_	_
33	from	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
36	5	_	NUM	_	NumType=Card	_	_	_	_
37	'	_	PUNCT	_	_	_	_	_	_
38	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
39	region	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	human	_	ADJ	_	Degree=Pos	_	_	_	_
43	eotaxin	_	NOUN	_	Number=Sing	_	_	_	_
44	gene	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Among	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	potentially	_	ADV	_	_	_	_	_	_
7	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	eotaxin	_	NOUN	_	Degree=Pos	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	effects	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	drugs	_	NOUN	_	Number=Plur	_	_	_	_
20	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
21	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	consensus	_	NOUN	_	Number=Sing	_	_	_	_
23	sequences	_	NOUN	_	Number=Plur	_	_	_	_
24	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	factors	_	NOUN	_	Number=Plur	_	_	_	_
30	like	_	ADP	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	IL6	_	PROPN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	AP	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappa	_	NOUN	_	Number=Sing	_	_	_	_
43	-B	_	NOUN	_	Number=Sing	_	_	_	_
44	like	_	ADP	_	_	_	_	_	_
45	consensus	_	NOUN	_	Number=Sing	_	_	_	_
46	sequence	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	gamma	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	interferon	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	as	_	ADV	_	_	_	_	_	_
53	well	_	ADV	_	Degree=Pos	_	_	_	_
54	as	_	ADP	_	_	_	_	_	_
55	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
56	response	_	NOUN	_	Number=Sing	_	_	_	_
57	elements	_	NOUN	_	Number=Plur	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002148	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Calcium	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	early	_	ADJ	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	induction	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	negatively	_	ADV	_	_	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	p21Ha	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	ras	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	early	_	ADJ	_	Degree=Pos	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	IE	_	X	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	such	_	ADJ	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	egr	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	rapidly	_	ADV	_	_	_	_	_	_
26	after	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	T	_	PROPN	_	Number=Sing	_	_	_	_
31	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	process	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	calcium	_	NOUN	_	Number=Sing	_	_	_	_
7	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	C	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	PKC	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
22	kinases	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	p21	_	NOUN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	ras	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	guanine	_	NOUN	_	Degree=Pos	_	_	_	_
8	nucleotide	_	NOUN	_	Degree=Pos	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
14	signal	_	NOUN	_	Number=Sing	_	_	_	_
15	transduction	_	NOUN	_	Number=Sing	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	PKC	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	PKC	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	independent	_	ADJ	_	Degree=Pos	_	_	_	_
24	pathways	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	involvement	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p21(ras	_	NOUN	_	Number=Plur	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	calcium	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	signals	_	NOUN	_	Number=Plur	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	through	_	ADP	_	_	_	_	_	_
18	analysis	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	AT	_	NOUN	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	inductions	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IE	_	PROPN	_	Number=Sing	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	calcium	_	NOUN	_	VerbForm=Inf	_	_	_	_
14	signals	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	presence	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	p21	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	ras	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	correlated	_	ADJ	_	Degree=Pos	_	_	_	_
32	consequences	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	p21	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	ras	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	negatively	_	ADV	_	_	_	_	_	_
10	regulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	IE	_	ADJ	_	Number=Sing	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	calcium	_	NOUN	_	Number=Sing	_	_	_	_
18	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	calcium	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	IE	_	X	_	_	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	reversed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	treatment	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
16	A	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	involvement	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	regulation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	later	_	ADJ	_	Degree=Cmp	_	_	_	_
3	result	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	pathway	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	p21(ras	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	down	_	ADV	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	AP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
29	coordinate	_	ADJ	_	Degree=Pos	_	_	_	_
30	reductions	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	protein	_	NOUN	_	Number=Sing	_	_	_	_
39	production	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	p2l	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	ras	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	essential	_	ADJ	_	Degree=Pos	_	_	_	_
12	mediator	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	SCONJ	_	_	_	_	_	_
14	generating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	only	_	ADV	_	_	_	_	_	_
17	positive	_	ADJ	_	Degree=Pos	_	_	_	_
18	but	_	CCONJ	_	_	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	negative	_	ADJ	_	Degree=Pos	_	_	_	_
21	modulatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
23	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	competence	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	T	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	response	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	inductive	_	ADJ	_	Degree=Pos	_	_	_	_
33	stimulations	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002155	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	X2	_	PROPN	_	Number=Sing	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	DRA	_	PROPN	_	Number=Sing	_	_	_	_
9	X2	_	NUM	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	box	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	activator	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	cloning	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	class	_	NOUN	_	Number=Sing	_	_	_	_
3	II	_	NUM	_	NumType=Card	_	_	_	_
4	MHC	_	PROPN	_	Number=Sing	_	_	_	_

1	Ag	_	NOUN	_	Number=Sing	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	family	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	surface	_	NOUN	_	Number=Sing	_	_	_	_
8	glycoproteins	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	limited	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	B	_	NOUN	_	Degree=Pos	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
11	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	many	_	ADJ	_	Degree=Pos	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	IFN	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	sequences	_	NOUN	_	Number=Plur	_	_	_	_
5	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	tissue	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	class	_	NOUN	_	Number=Sing	_	_	_	_
13	II	_	NUM	_	Number=Sing	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	DRA	_	PROPN	_	Number=Sing	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	one	_	NUM	_	NumType=Card	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	cis	_	NOUN	_	Number=Plur	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	motifs	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	X2	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	box	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	X2	_	PROPN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	X2	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	binds	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	present	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	isolation	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	characterization	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	full	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	length	_	NOUN	_	Number=Sing	_	_	_	_
14	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
15	clone	_	NOUN	_	Number=Sing	_	_	_	_
16	encoding	_	VERB	_	Number=Sing	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	X2	_	PROPN	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
3	clone	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
9	cloning	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	together	_	ADV	_	_	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	c-Fos	_	NOUN	_	Number=Sing	_	_	_	_
22	forms	_	NOUN	_	Number=Plur	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	heterodimeric	_	ADJ	_	Degree=Pos	_	_	_	_
25	activator	_	NOUN	_	Number=Sing	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	complex	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	c-Fos/c-Jun	_	NOUN	_	Degree=Pos	_	_	_	_
3	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
4	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	exist	_	VERB	_	VerbForm=Inf	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	B	_	ADJ	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
12	form	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	X2	_	NUM	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	box	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	class	_	NOUN	_	Number=Sing	_	_	_	_
22	II	_	NUM	_	NumType=Card	_	_	_	_
23	nonexpressing	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	c-Fos/c-Jun	_	NOUN	_	Degree=Pos	_	_	_	_
4	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
5	might	_	AUX	_	VerbForm=Fin	_	_	_	_
6	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	repression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	DRA	_	PROPN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002158	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	lymphotoxin	_	NOUN	_	Number=Sing	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	tax	_	VERB	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
20	lines	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	activator	_	NOUN	_	Number=Sing	_	_	_	_
7	tax	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	gain	_	VERB	_	VerbForm=Inf	_	_	_	_
12	insight	_	NOUN	_	Number=Sing	_	_	_	_
13	into	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	lymphotoxin	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	LT	_	NOUN	_	Number=Sing	_	_	_	_
20	;	_	PUNCT	_	_	_	_	_	_
21	TNF	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	beta	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	induction	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	lines	_	NOUN	_	Number=Plur	_	_	_	_
6	produce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	LT	_	NOUN	_	Number=Sing	_	_	_	_
8	biologic	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	LT	_	NOUN	_	Number=Sing	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	LT	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	293	_	NUM	_	NumType=Card	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	CAT	_	NOUN	_	Number=Sing	_	_	_	_
10	construct	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	active	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	LT	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	C81-66	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	SYM	_	_	_	_	_	_
28	45	_	NUM	_	NumType=Card	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	line	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	defective	_	ADJ	_	Degree=Pos	_	_	_	_
35	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
38	but	_	CCONJ	_	_	_	_	_	_
39	expresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	tax	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	observation	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	PRON	_	PronType=Rel	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	LT	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	construct	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	M1	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	CAT	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	C81-66	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	SYM	_	_	_	_	_	_
21	45	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	confirmed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	importance	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	LT	_	PROPN	_	Number=Sing	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	into	_	ADP	_	_	_	_	_	_
5	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	I	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	negative	_	ADJ	_	Degree=Pos	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
12	lines	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	stably	_	ADV	_	_	_	_	_	_
5	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	tax	_	NOUN	_	Number=Sing	_	_	_	_
7	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	directly	_	ADV	_	_	_	_	_	_
17	bound	_	VERB	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	LT	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	co	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	reporter	_	NOUN	_	Number=Sing	_	_	_	_
7	constructs	_	NOUN	_	Number=Plur	_	_	_	_
8	into	_	ADP	_	_	_	_	_	_
9	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	maximally	_	ADV	_	_	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_

1	HTLV-I-LTR	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	CAT	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_
6	B-	_	PROPN	_	Number=Sing	_	_	_	_
7	fos	_	ADP	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	CAT	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	LT	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	293	_	NUM	_	NumType=Card	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	lesser	_	ADJ	_	Degree=Cmp	_	_	_	_
19	extent	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	JM	_	PROPN	_	Number=Sing	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	tax	_	NOUN	_	Number=Sing	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	LT	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	293	_	NUM	_	NumType=Card	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	two	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	four	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	fold	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	though	_	SCONJ	_	_	_	_	_	_
21	there	_	PRON	_	_	_	_	_	_
22	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	no	_	DET	_	_	_	_	_	_
24	induction	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	M1	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	CAT	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	increase	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	LT	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	293	_	NUM	_	NumType=Card	_	_	_	_
7	CAT	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	mirrored	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	increase	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	LT	_	PROPN	_	Number=Sing	_	_	_	_
14	biologic	_	ADJ	_	Degree=Pos	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	under	_	ADP	_	_	_	_	_	_
18	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
19	conditions	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	demonstrate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	induction	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	LT	_	NOUN	_	Number=Sing	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	over	_	ADP	_	_	_	_	_	_
14	basal	_	ADJ	_	Degree=Pos	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	tax	_	NOUN	_	Number=Sing	_	_	_	_
23	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	low	_	ADJ	_	Degree=Pos	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	level	_	NOUN	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	both	_	CCONJ	_	_	_	_	_	_
30	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
31	LT	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	LT	_	NOUN	_	Number=Sing	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	at	_	ADV	_	_	_	_	_	_
38	least	_	ADV	_	Degree=Sup	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	part	_	NOUN	_	Number=Sing	_	_	_	_
41	through	_	ADP	_	_	_	_	_	_
42	activation	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	NF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	kappa	_	PROPN	_	Number=Sing	_	_	_	_
47	B.	_	PROPN	_	Number=Sing	_	_	_	_
48	Document	_	NOUN	_	Number=Sing	_	_	_	_
49	003002162	_	NUM	_	NumType=Card	_	_	_	_
50	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Triggering	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HLA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	DR	_	PROPN	_	Number=Sing	_	_	_	_
6	antigens	_	NOUN	_	Number=Plur	_	_	_	_
7	differentially	_	ADV	_	_	_	_	_	_
8	modulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	release	_	VERB	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	B	_	ADJ	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
19	stage	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	maturation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Triggering	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HLA	_	PROPN	_	Number=Sing	_	_	_	_
4	class	_	NOUN	_	Number=Sing	_	_	_	_
5	II	_	NUM	_	NumType=Card	_	_	_	_
6	antigens	_	NOUN	_	Number=Plur	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	anti-HLA	_	ADJ	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	DR	_	PROPN	_	Number=Sing	_	_	_	_
12	monoclonal	_	ADJ	_	Number=Sing	_	_	_	_
13	antibody	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	mAb	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	L243	_	PROPN	_	Number=Sing	_	_	_	_
18	significantly	_	ADV	_	_	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	P	_	NOUN	_	Number=Sing	_	_	_	_
21	<	_	PUNCT	_	_	_	_	_	_
22	0.05	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	differentially	_	ADV	_	_	_	_	_	_
26	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	release	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	tumor	_	NOUN	_	Number=Sing	_	_	_	_
31	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	TNF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	non-Hodgkin	_	NOUN	_	Number=Sing	_	_	_	_
42	's	_	PART	_	_	_	_	_	_
43	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_

1	Ri-I	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Ci	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	I	_	PROPN	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Sc	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Int	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
17	stage	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	more	_	ADV	_	_	_	_	_	_
28	mature	_	ADJ	_	Degree=Pos	_	_	_	_
29	Burkitt	_	NOUN	_	Number=Sing	_	_	_	_
30	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	Raji	_	PROPN	_	Number=Sing	_	_	_	_
33	;	_	PUNCT	_	_	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	contrast	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
38	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
39	not	_	PART	_	_	_	_	_	_
40	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
41	TNF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	alpha	_	NOUN	_	Number=Sing	_	_	_	_
44	release	_	NOUN	_	Number=Sing	_	_	_	_
45	by	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
48	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
49	cells	_	NOUN	_	Number=Plur	_	_	_	_
50	Nalm	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	6	_	NUM	_	NumType=Card	_	_	_	_
53	and	_	CCONJ	_	_	_	_	_	_
54	BV173	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	release	_	NOUN	_	Number=Sing	_	_	_	_
5	peaked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	24	_	NUM	_	NumType=Card	_	_	_	_
8	h	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	thereafter	_	ADV	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	dose	_	ADV	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	preceded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	increase	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	TNF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
28	detectable	_	ADJ	_	Number=Sing	_	_	_	_
29	after	_	ADP	_	_	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	h	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	mAb	_	PROPN	_	Number=Sing	_	_	_	_
36	L243	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	TNF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	alpha	_	PROPN	_	Number=Sing	_	_	_	_
5	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	activator	_	NOUN	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	AP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	;	_	PUNCT	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	fact	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	triggering	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	HLA	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	DR	_	PROPN	_	Number=Sing	_	_	_	_
41	antigens	_	NOUN	_	Number=Plur	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	presence	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	antihuman	_	ADJ	_	Degree=Pos	_	_	_	_
47	TNF	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	alpha	_	NOUN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	neutralizing	_	VERB	_	VerbForm=Ger	_	_	_	_
52	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
53	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
54	not	_	PART	_	_	_	_	_	_
55	upregulate	_	VERB	_	VerbForm=Inf	_	_	_	_
56	NF	_	PROPN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	kappa	_	PROPN	_	Number=Sing	_	_	_	_
59	B	_	NOUN	_	Number=Sing	_	_	_	_
60	and	_	CCONJ	_	_	_	_	_	_
61	AP	_	NOUN	_	Number=Sing	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	1	_	NUM	_	NumType=Card	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	released	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	TNF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	homotypic	_	ADJ	_	Degree=Pos	_	_	_	_
14	aggregation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	Ri-I	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	Ci-I	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	Sc	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	I	_	PROPN	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	Raji	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	mAb	_	PROPN	_	Number=Sing	_	_	_	_
30	L243	_	PROPN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
34	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	not	_	PART	_	_	_	_	_	_
36	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	B	_	PROPN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Altogether	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
7	:	_	PUNCT	_	_	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	a	_	X	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	ability	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	B	_	ADJ	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	release	_	VERB	_	VerbForm=Inf	_	_	_	_
18	TNF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	after	_	ADP	_	_	_	_	_	_
22	triggering	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	HLA	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	DR	_	PROPN	_	Number=Sing	_	_	_	_
27	antigens	_	NOUN	_	Number=Plur	_	_	_	_
28	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	stage	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
34	;	_	PUNCT	_	_	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	b	_	X	_	_	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	levels	_	NOUN	_	Number=Plur	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	released	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	TNF	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	alpha	_	NOUN	_	Number=Sing	_	_	_	_
44	seem	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
45	to	_	PART	_	_	_	_	_	_
46	correlate	_	VERB	_	VerbForm=Inf	_	_	_	_
47	with	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	stage	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	B	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	cell	_	NOUN	_	Number=Sing	_	_	_	_
54	maturation	_	NOUN	_	Number=Sing	_	_	_	_
55	but	_	CCONJ	_	_	_	_	_	_
56	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
57	not	_	PART	_	_	_	_	_	_
58	correlate	_	VERB	_	VerbForm=Inf	_	_	_	_
59	with	_	ADP	_	_	_	_	_	_
60	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
61	amounts	_	NOUN	_	Number=Plur	_	_	_	_
62	of	_	ADP	_	_	_	_	_	_
63	cell	_	NOUN	_	Number=Sing	_	_	_	_
64	surface	_	NOUN	_	Number=Sing	_	_	_	_
65	HLA	_	NOUN	_	Number=Sing	_	_	_	_
66	-	_	PUNCT	_	_	_	_	_	_
67	DR	_	NOUN	_	Number=Sing	_	_	_	_
68	antigens	_	NOUN	_	Number=Plur	_	_	_	_
69	;	_	PUNCT	_	_	_	_	_	_
70	(	_	PUNCT	_	_	_	_	_	_
71	c	_	X	_	Number=Sing	_	_	_	_
72	)	_	PUNCT	_	_	_	_	_	_
73	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
74	TNF	_	PROPN	_	Number=Sing	_	_	_	_
75	-	_	PUNCT	_	_	_	_	_	_
76	alpha	_	NOUN	_	Number=Sing	_	_	_	_
77	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
78	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
79	levels	_	NOUN	_	Number=Plur	_	_	_	_
80	of	_	ADP	_	_	_	_	_	_
81	expression	_	NOUN	_	Number=Sing	_	_	_	_
82	of	_	ADP	_	_	_	_	_	_
83	NF	_	PROPN	_	Number=Sing	_	_	_	_
84	-	_	PUNCT	_	_	_	_	_	_
85	kappa	_	NOUN	_	Number=Sing	_	_	_	_
86	B	_	NOUN	_	Number=Sing	_	_	_	_
87	and	_	CCONJ	_	_	_	_	_	_
88	AP	_	NOUN	_	Number=Sing	_	_	_	_
89	-	_	PUNCT	_	_	_	_	_	_
90	1	_	NUM	_	NumType=Card	_	_	_	_
91	by	_	ADP	_	_	_	_	_	_
92	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
93	autocrine	_	NOUN	_	Number=Sing	_	_	_	_
94	loop	_	NOUN	_	Number=Sing	_	_	_	_
95	;	_	PUNCT	_	_	_	_	_	_
96	and	_	CCONJ	_	_	_	_	_	_
97	(	_	PUNCT	_	_	_	_	_	_
98	d	_	X	_	Number=Sing	_	_	_	_
99	)	_	PUNCT	_	_	_	_	_	_
100	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
101	signals	_	NOUN	_	Number=Plur	_	_	_	_
102	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
103	TNF	_	PROPN	_	Number=Sing	_	_	_	_
104	-	_	PUNCT	_	_	_	_	_	_
105	alpha	_	NOUN	_	Number=Sing	_	_	_	_
106	release	_	NOUN	_	Number=Sing	_	_	_	_
107	by	_	ADP	_	_	_	_	_	_
108	B	_	NOUN	_	Number=Sing	_	_	_	_
109	cells	_	NOUN	_	Number=Plur	_	_	_	_
110	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
111	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
112	from	_	ADP	_	_	_	_	_	_
113	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
114	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
115	homotypic	_	ADJ	_	Degree=Pos	_	_	_	_
116	aggregation	_	NOUN	_	Number=Sing	_	_	_	_
117	and	_	CCONJ	_	_	_	_	_	_
118	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
119	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002164	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Barr	_	PROPN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
7	latent	_	ADJ	_	Degree=Pos	_	_	_	_
8	membrane	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	engages	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	tumor	_	NOUN	_	Number=Sing	_	_	_	_
14	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	TRADD	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	RIP	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	not	_	PART	_	_	_	_	_	_
32	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
33	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	require	_	VERB	_	VerbForm=Inf	_	_	_	_
36	RIP	_	NOUN	_	Number=Sing	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
41	activation	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	site	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Barr	_	PROPN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	EBV	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	constitutively	_	ADV	_	_	_	_	_	_
17	associates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	tumor	_	NOUN	_	Number=Sing	_	_	_	_
21	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	TNFR1	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	death	_	NOUN	_	Number=Sing	_	_	_	_
31	domain	_	NOUN	_	Number=Sing	_	_	_	_
32	protein	_	NOUN	_	Number=Sing	_	_	_	_
33	TRADD	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
41	N	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
44	kinase	_	NOUN	_	Number=Sing	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
47	critical	_	ADJ	_	Degree=Pos	_	_	_	_
48	for	_	ADP	_	_	_	_	_	_
49	long	_	ADJ	_	Degree=Pos	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	term	_	NOUN	_	Number=Sing	_	_	_	_
52	lymphoblastoid	_	NOUN	_	Number=Sing	_	_	_	_
53	cell	_	NOUN	_	Number=Sing	_	_	_	_
54	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
6	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
7	through	_	ADP	_	_	_	_	_	_
8	TRADD	_	PROPN	_	Number=Sing	_	_	_	_
9	differs	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	TNFR1	_	PROPN	_	Number=Sing	_	_	_	_
12	signaling	_	VERB	_	Number=Sing	_	_	_	_
13	through	_	ADP	_	_	_	_	_	_
14	TRADD	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
2	needs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	only	_	ADV	_	_	_	_	_	_
4	11	_	NUM	_	NumType=Card	_	_	_	_
5	amino	_	ADJ	_	Degree=Pos	_	_	_	_
6	acids	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	synergize	_	VERB	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	TRADD	_	PROPN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	while	_	SCONJ	_	_	_	_	_	_
23	TNFR1	_	PROPN	_	Number=Sing	_	_	_	_
24	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	approximately	_	ADV	_	_	_	_	_	_
26	70	_	NUM	_	NumType=Card	_	_	_	_
27	residues	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
4	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	require	_	VERB	_	VerbForm=Inf	_	_	_	_
7	TRADD	_	PROPN	_	Number=Sing	_	_	_	_
8	residues	_	NOUN	_	Number=Plur	_	_	_	_
9	294	_	NUM	_	NumType=Card	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	312	_	NUM	_	NumType=Card	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	while	_	SCONJ	_	_	_	_	_	_
19	TNFR1	_	PROPN	_	Number=Sing	_	_	_	_
20	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	TRADD	_	PROPN	_	Number=Sing	_	_	_	_
22	residues	_	NOUN	_	Number=Plur	_	_	_	_
23	296	_	NUM	_	NumType=Card	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	302	_	NUM	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	partially	_	ADV	_	_	_	_	_	_
4	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	TRADD	_	ADJ	_	Number=Sing	_	_	_	_
13	mutant	_	NOUN	_	Number=Sing	_	_	_	_
14	consisting	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	residues	_	NOUN	_	Number=Plur	_	_	_	_
17	122	_	NUM	_	NumType=Card	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	293	_	NUM	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Unlike	_	ADP	_	_	_	_	_	_
2	TNFR1	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
5	can	_	AUX	_	VerbForm=Fin	_	_	_	_
6	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
7	directly	_	ADV	_	_	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	RIP	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	stably	_	ADV	_	_	_	_	_	_
18	associates	_	VERB	_	Number=Plur	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	RIP	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	EBV	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	lymphoblastoid	_	ADJ	_	Degree=Pos	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	lines	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Surprisingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
4	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	require	_	VERB	_	VerbForm=Inf	_	_	_	_
7	RIP	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Despite	_	ADP	_	_	_	_	_	_
2	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
3	association	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	TRADD	_	PROPN	_	Number=Sing	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	RIP	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
10	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
13	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	EBV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	negative	_	ADJ	_	Degree=Pos	_	_	_	_
18	Burkitt	_	NOUN	_	Number=Sing	_	_	_	_
19	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
23	kidney	_	NOUN	_	Number=Sing	_	_	_	_
24	293	_	NUM	_	NumType=Card	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	add	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	different	_	ADJ	_	Degree=Pos	_	_	_	_
6	perspective	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
10	interactions	_	NOUN	_	Number=Plur	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	TRADD	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	RIP	_	NOUN	_	Number=Sing	_	_	_	_
19	participate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	growth	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002175	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	caspase	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
16	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
17	without	_	ADP	_	_	_	_	_	_
18	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	caspase	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	3	_	NUM	_	NumType=Card	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	involved	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	control	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	various	_	ADJ	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	act	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	extrinsic	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	intrinsic	_	ADJ	_	Degree=Pos	_	_	_	_
20	survival	_	NOUN	_	Number=Sing	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	suppression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	permeable	_	ADJ	_	Degree=Pos	_	_	_	_
16	SN50	_	NOUN	_	Number=Sing	_	_	_	_
17	peptide	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	masks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	localization	_	NOUN	_	Number=Sing	_	_	_	_
24	sequence	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B1	_	NUM	_	Number=Sing	_	_	_	_
30	dimers	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
35	localization	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	SCONJ	_	_	_	_	_	_
40	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
41	normal	_	ADJ	_	Degree=Pos	_	_	_	_
42	human	_	ADJ	_	Degree=Pos	_	_	_	_
43	PBL	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	externalization	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	phosphatidylserine	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	breaks	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	morphological	_	ADJ	_	Degree=Pos	_	_	_	_
21	changes	_	NOUN	_	Number=Plur	_	_	_	_
22	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	fragmentation	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	efficiently	_	ADV	_	_	_	_	_	_
5	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	caspase	_	NOUN	_	Number=Sing	_	_	_	_
9	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
10	Z-VAD	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	fmk	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	partially	_	ADV	_	_	_	_	_	_
15	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	Ac	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	DEVD	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	fmk	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	SN50	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	mediated	_	VERB	_	Degree=Pos	_	_	_	_
28	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	caspase	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	suppression	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	contrast	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	TPEN	_	PROPN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	N	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	N	_	PROPN	_	Number=Sing	_	_	_	_
23	,N',N'-tetrakis	_	PROPN	_	Number=Sing	_	_	_	_
24	[	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	pyridylmethyl	_	NOUN	_	Number=Sing	_	_	_	_
28	]	_	PUNCT	_	_	_	_	_	_
29	ethylenediamine	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	soluble	_	ADJ	_	Number=Sing	_	_	_	_
33	Fas	_	NOUN	_	Number=Sing	_	_	_	_
34	ligand	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	CD95	_	PROPN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
40	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	absence	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	active	_	ADJ	_	Degree=Pos	_	_	_	_
46	death	_	NOUN	_	Number=Sing	_	_	_	_
47	effector	_	NOUN	_	Number=Sing	_	_	_	_
48	proteases	_	NOUN	_	Number=Plur	_	_	_	_
49	caspase	_	NOUN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	1-	_	NUM	_	NumType=Card	_	_	_	_
52	like	_	INTJ	_	_	_	_	_	_
53	(	_	PUNCT	_	_	_	_	_	_
54	IL	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	1	_	NUM	_	NumType=Card	_	_	_	_
57	converting	_	VERB	_	VerbForm=Ger	_	_	_	_
58	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	,	_	PUNCT	_	_	_	_	_	_
61	caspase	_	NOUN	_	Number=Sing	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	3-	_	NUM	_	NumType=Card	_	_	_	_
64	like	_	ADP	_	_	_	_	_	_
65	(	_	PUNCT	_	_	_	_	_	_
66	CPP32	_	NOUN	_	Number=Sing	_	_	_	_
67	/	_	PUNCT	_	_	_	_	_	_
68	Yama	_	PROPN	_	Number=Sing	_	_	_	_
69	/	_	PUNCT	_	_	_	_	_	_
70	apopain	_	NOUN	_	Number=Sing	_	_	_	_
71	)	_	PUNCT	_	_	_	_	_	_
72	,	_	PUNCT	_	_	_	_	_	_
73	and	_	CCONJ	_	_	_	_	_	_
74	caspase	_	NOUN	_	Number=Sing	_	_	_	_
75	-6	_	NUM	_	NumType=Card	_	_	_	_
76	-	_	PUNCT	_	_	_	_	_	_
77	like	_	ADP	_	Degree=Pos	_	_	_	_
78	and	_	CCONJ	_	_	_	_	_	_
79	without	_	ADP	_	_	_	_	_	_
80	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
81	of	_	ADP	_	_	_	_	_	_
82	caspase	_	NOUN	_	Number=Sing	_	_	_	_
83	-	_	PUNCT	_	_	_	_	_	_
84	3	_	NUM	_	NumType=Card	_	_	_	_
85	substrates	_	NOUN	_	Number=Plur	_	_	_	_
86	poly	_	NOUN	_	Number=Sing	_	_	_	_
87	(	_	PUNCT	_	_	_	_	_	_
88	ADP	_	NOUN	_	Number=Sing	_	_	_	_
89	-	_	PUNCT	_	_	_	_	_	_
90	ribose	_	NOUN	_	Number=Sing	_	_	_	_
91	)	_	PUNCT	_	_	_	_	_	_
92	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
93	and	_	CCONJ	_	_	_	_	_	_
94	DNA	_	NOUN	_	Number=Sing	_	_	_	_
95	fragmentation	_	NOUN	_	Number=Sing	_	_	_	_
96	factor	_	NOUN	_	Number=Sing	_	_	_	_
97	-	_	PUNCT	_	_	_	_	_	_
98	45	_	NUM	_	NumType=Card	_	_	_	_
99	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	either	_	CCONJ	_	_	_	_	_	_
5	low	_	ADJ	_	Degree=Pos	_	_	_	_
6	level	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	that	_	DET	_	_	_	_	_	_
13	different	_	ADJ	_	Degree=Pos	_	_	_	_
14	caspases	_	NOUN	_	Number=Plur	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	involved	_	VERB	_	Degree=Pos	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Preactivation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	translocation	_	NOUN	_	Number=Sing	_	_	_	_
13	protected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	SN50	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	essential	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	survival	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	naive	_	ADJ	_	Degree=Pos	_	_	_	_
16	PBL	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002177	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Dysregulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	oxidized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	low	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	density	_	NOUN	_	Number=Sing	_	_	_	_
14	lipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	Rel	_	NOUN	_	Number=Sing	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	involved	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	as	_	SCONJ	_	_	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	presence	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	human	_	ADJ	_	Degree=Pos	_	_	_	_
36	atherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
37	lesions	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	aim	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	present	_	ADJ	_	Degree=Pos	_	_	_	_
6	study	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	effects	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	oxidized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	LDL	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	oxLDL	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	system	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	THP	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	as	_	ADV	_	_	_	_	_	_
33	well	_	ADV	_	Degree=Pos	_	_	_	_
34	as	_	ADP	_	_	_	_	_	_
35	adherent	_	ADJ	_	Degree=Pos	_	_	_	_
36	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	short	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	term	_	NOUN	_	Number=Sing	_	_	_	_
8	incubation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	oxLDL	_	ADV	_	Number=Sing	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	p50/p65	_	NOUN	_	Number=Sing	_	_	_	_
16	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	dimers	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	target	_	NOUN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	8	_	NUM	_	NumType=Card	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	H2O2	_	PROPN	_	Number=Sing	_	_	_	_
15	scavenger	_	NOUN	_	Number=Sing	_	_	_	_
16	pyrrolidine	_	NOUN	_	Number=Sing	_	_	_	_
17	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	proteasome	_	ADJ	_	Number=Sing	_	_	_	_
21	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
22	PSI	_	PROPN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	oxLDL	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	initial	_	ADJ	_	Degree=Pos	_	_	_	_
15	depletion	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	slight	_	ADJ	_	Degree=Pos	_	_	_	_
26	transient	_	NOUN	_	Number=Sing	_	_	_	_
27	increase	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	level	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
34	protein	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	long	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	term	_	NOUN	_	Number=Sing	_	_	_	_
7	treatment	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	oxLDL	_	NOUN	_	Number=Sing	_	_	_	_
10	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	depletion	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	accompanied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	both	_	CCONJ	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	tumor	_	NOUN	_	Number=Sing	_	_	_	_
39	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
40	factor	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	alpha	_	NOUN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	beta	_	NOUN	_	Number=Sing	_	_	_	_
48	genes	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	additional	_	ADJ	_	Degree=Pos	_	_	_	_
5	evidence	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	oxLDL	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	potent	_	ADJ	_	Degree=Pos	_	_	_	_
11	modulator	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	dys	_	NOUN	_	Number=Plur	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	regulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	Rel	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	likely	_	ADJ	_	Degree=Pos	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	play	_	VERB	_	VerbForm=Inf	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	important	_	ADJ	_	Degree=Pos	_	_	_	_
35	role	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	atherogenesis	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002181	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	8	_	NUM	_	NumType=Card	_	_	_	_
5	AP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	like	_	ADJ	_	Degree=Pos	_	_	_	_
13	sites	_	NOUN	_	Number=Plur	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
16	end	_	NOUN	_	Number=Sing	_	_	_	_
17	targets	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	FK506	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
22	pathway	_	NOUN	_	Number=Sing	_	_	_	_
23	accompanied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	calcium	_	NOUN	_	Number=Sing	_	_	_	_
26	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	FK506	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	immunosuppressant	_	ADJ	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	production	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	several	_	ADJ	_	Degree=Pos	_	_	_	_
11	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	FK506	_	PROPN	_	Number=Sing	_	_	_	_
5	suppressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	8	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	8	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	line	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
34	12	_	NUM	_	NumType=Card	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	myristate	_	NOUN	_	Number=Sing	_	_	_	_
37	13	_	NUM	_	NumType=Card	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	acetate	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	PMA	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	calcium	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
47	+	_	SYM	_	_	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
50	(	_	PUNCT	_	_	_	_	_	_
51	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	mutated	_	VERB	_	Degree=Pos	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	8	_	NUM	_	NumType=Card	_	_	_	_
11	promoters	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	like	_	ADJ	_	Degree=Pos	_	_	_	_
22	sites	_	NOUN	_	Number=Plur	_	_	_	_
23	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
28	elements	_	NOUN	_	Number=Plur	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	PMA	_	PROPN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	ionomycin	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	FK506	_	PROPN	_	Number=Sing	_	_	_	_
2	suppressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcriptions	_	NOUN	_	Number=Plur	_	_	_	_
5	through	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	AP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	like	_	ADJ	_	Degree=Pos	_	_	_	_
15	sites	_	NOUN	_	Number=Plur	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	PMA	_	PROPN	_	Number=Sing	_	_	_	_
19	plus	_	CCONJ	_	_	_	_	_	_
20	Ca	_	PROPN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	+	_	SYM	_	_	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	mobilizing	_	VERB	_	Number=Sing	_	_	_	_
27	agents	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	not	_	ADV	_	_	_	_	_	_
31	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
32	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	Ca	_	PROPN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	+	_	SYM	_	_	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	independent	_	ADJ	_	Degree=Pos	_	_	_	_
41	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	gel	_	NOUN	_	Number=Sing	_	_	_	_
3	retardation	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	FK506	_	PROPN	_	Number=Sing	_	_	_	_
7	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	little	_	ADJ	_	Degree=Pos	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	PMA	_	PROPN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	factors	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	anti-JunD	_	NOUN	_	Degree=Pos	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	c	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	Fos	_	PROPN	_	Number=Sing	_	_	_	_
37	antibody	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	FK506	_	NOUN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	EGTA	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_
10	chelator	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	similarly	_	ADV	_	_	_	_	_	_
13	affected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	formation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	like	_	ADJ	_	Degree=Pos	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	complexes	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	any	_	DET	_	_	_	_	_	_
31	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
32	against	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	human	_	ADJ	_	Degree=Pos	_	_	_	_
35	Rel	_	NOUN	_	Number=Sing	_	_	_	_
36	family	_	NOUN	_	Number=Sing	_	_	_	_
37	proteins	_	NOUN	_	Number=Plur	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	c	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	Rel	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	p65	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	p50	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	p49	_	NOUN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	confirmed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	previous	_	ADJ	_	Degree=Pos	_	_	_	_
7	report	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	FK506	_	PROPN	_	Number=Sing	_	_	_	_
10	suppressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	PMA	_	PROPN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	authentic	_	ADJ	_	Degree=Pos	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	immunoglobulin	_	PROPN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	Ig	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	which	_	PRON	_	PronType=Int	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappa	_	NOUN	_	Number=Sing	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	binding	_	NOUN	_	Number=Sing	_	_	_	_
37	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
38	also	_	ADV	_	_	_	_	_	_
39	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	FK506	_	PROPN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
44	that	_	SCONJ	_	_	_	_	_	_
45	both	_	CCONJ	_	_	_	_	_	_
46	IL	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	8	_	NUM	_	NumType=Card	_	_	_	_
49	kappa	_	NOUN	_	Number=Sing	_	_	_	_
50	B	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	like	_	ADJ	_	Degree=Pos	_	_	_	_
53	site	_	NOUN	_	Number=Sing	_	_	_	_
54	and	_	CCONJ	_	_	_	_	_	_
55	Ig	_	PROPN	_	Number=Sing	_	_	_	_
56	kappa	_	NOUN	_	Number=Sing	_	_	_	_
57	B	_	NOUN	_	Number=Sing	_	_	_	_
58	site	_	NOUN	_	Number=Sing	_	_	_	_
59	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
60	FK506	_	NUM	_	NumType=Card	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
63	in	_	ADP	_	_	_	_	_	_
64	spite	_	NOUN	_	Number=Sing	_	_	_	_
65	of	_	ADP	_	_	_	_	_	_
66	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
67	difference	_	NOUN	_	Number=Sing	_	_	_	_
68	of	_	ADP	_	_	_	_	_	_
69	binding	_	NOUN	_	Number=Sing	_	_	_	_
70	factors	_	NOUN	_	Number=Plur	_	_	_	_
71	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	not	_	ADV	_	_	_	_	_	_
6	only	_	ADV	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	AT	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	NFIL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2A	_	PROPN	_	Number=Sing	_	_	_	_
19	sites	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	Ig	_	PROPN	_	Number=Sing	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	also	_	ADV	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	8	_	NUM	_	NumType=Card	_	_	_	_
32	AP	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	kappa	_	NOUN	_	Number=Sing	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	like	_	ADJ	_	Degree=Pos	_	_	_	_
40	sites	_	NOUN	_	Number=Plur	_	_	_	_
41	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
42	terminals	_	NOUN	_	Number=Plur	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	FK506	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
47	pathway	_	NOUN	_	Number=Sing	_	_	_	_
48	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
49	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
50	+	_	SYM	_	_	_	_	_	_
51	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002182	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interactions	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	activator	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	env	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	mouse	_	NOUN	_	Number=Sing	_	_	_	_
13	mammary	_	ADJ	_	Number=Sing	_	_	_	_
14	tumor	_	NOUN	_	Number=Sing	_	_	_	_
15	virus	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	transacting	_	NOUN	_	Number=Sing	_	_	_	_
26	factors	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mouse	_	NOUN	_	Number=Sing	_	_	_	_
3	mammary	_	ADJ	_	Number=Sing	_	_	_	_
4	tumor	_	NOUN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	env	_	NOUN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	activator	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	META	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	can	_	AUX	_	VerbForm=Fin	_	_	_	_
17	control	_	VERB	_	VerbForm=Inf	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
22	long	_	ADJ	_	Degree=Pos	_	_	_	_
23	terminal	_	NOUN	_	Number=Sing	_	_	_	_
24	repeat	_	ADJ	_	Number=Sing	_	_	_	_
25	region	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	control	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	META	_	PROPN	_	Number=Sing	_	_	_	_
5	parallels	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	_	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	several	_	ADJ	_	Degree=Pos	_	_	_	_
9	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	being	_	AUX	_	VerbForm=Ger	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	T	_	ADJ	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
28	drug	_	NOUN	_	Number=Sing	_	_	_	_
29	cyclosporine	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	CsA	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	DNase	_	PROPN	_	Number=Sing	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	footprinting	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	bound	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
17	site	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	META	_	PROPN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	P	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	distal	_	ADJ	_	Degree=Pos	_	_	_	_
29	site	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	META	_	PROPN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	D	_	NOUN	_	Number=Sing	_	_	_	_
34	+	_	SYM	_	_	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	within	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	400	_	NUM	_	NumType=Card	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	base	_	NOUN	_	Number=Sing	_	_	_	_
42	pair	_	NOUN	_	Number=Sing	_	_	_	_
43	META	_	NOUN	_	Number=Sing	_	_	_	_
44	region	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	but	_	CCONJ	_	_	_	_	_	_
7	not	_	ADV	_	_	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	bound	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	META	_	PROPN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	D	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	adjacent	_	ADJ	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	META	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	D	_	NOUN	_	Number=Sing	_	_	_	_
27	+	_	SYM	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	META	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	D	_	NOUN	_	Number=Sing	_	_	_	_
4	+	_	SYM	_	_	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	gel	_	NOUN	_	Number=Sing	_	_	_	_
16	shift	_	NOUN	_	Number=Sing	_	_	_	_
17	analysis	_	NOUN	_	Number=Sing	_	_	_	_
18	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	inducible	_	ADJ	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	CsA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	parallel	_	NOUN	_	Number=Sing	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	transfection	_	NOUN	_	Number=Sing	_	_	_	_
34	results	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Authentic	_	ADJ	_	Degree=Pos	_	_	_	_
2	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	targets	_	NOUN	_	Number=Plur	_	_	_	_
8	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	compete	_	VERB	_	VerbForm=Inf	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	META	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	D	_	NOUN	_	Number=Sing	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	s	_	X	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	SV40	_	NOUN	_	Number=Sing	_	_	_	_
3	core	_	NOUN	_	Number=Sing	_	_	_	_
4	sequence	_	NOUN	_	Number=Sing	_	_	_	_
5	competed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	META	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	D	_	NOUN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	META	_	PROPN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	D	_	NOUN	_	Number=Sing	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	compete	_	VERB	_	VerbForm=Inf	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	complexes	_	NOUN	_	Number=Plur	_	_	_	_
27	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	SV40	_	NOUN	_	Number=Sing	_	_	_	_
31	probe	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	together	_	ADV	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	META	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	D+	_	X	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	novel	_	NOUN	_	Number=Sing	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
18	element	_	NOUN	_	Number=Sing	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	similar	_	ADJ	_	Degree=Pos	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	type	_	NOUN	_	Number=Sing	_	_	_	_
27	specificity	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	dependence	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	CsA	_	NOUN	_	Number=Sing	_	_	_	_
34	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
38	element	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	be	_	AUX	_	VerbForm=Inf	_	_	_	_
4	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	MMTV	_	PROPN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Mls	_	PROPN	_	Number=Sing	_	_	_	_
14	antigens	_	NOUN	_	Number=Plur	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	lymphomas	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002185	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cytomegalovirus	_	PROPN	_	Number=Sing	_	_	_	_
2	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
3	early	_	ADJ	_	Degree=Pos	_	_	_	_
4	genes	_	NOUN	_	Number=Plur	_	_	_	_
5	upregulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
5	early	_	ADJ	_	Degree=Pos	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	IE	_	X	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	cytomegalovirus	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	CMV	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	can	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	known	_	VERB	_	Degree=Pos	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	viral	_	ADJ	_	Degree=Pos	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-6	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	6	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	central	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	numerous	_	ADJ	_	Degree=Pos	_	_	_	_
13	inflammatory	_	NOUN	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	immune	_	ADJ	_	Number=Sing	_	_	_	_
16	processes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	6	_	NUM	_	NumType=Card	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	lung	_	NOUN	_	Number=Sing	_	_	_	_
9	transplant	_	NOUN	_	Degree=Pos	_	_	_	_
10	patients	_	NOUN	_	Number=Plur	_	_	_	_
11	clinically	_	ADV	_	_	_	_	_	_
12	diagnosed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	CMV	_	PROPN	_	Number=Sing	_	_	_	_
15	pneumonitis	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	various	_	ADJ	_	Degree=Pos	_	_	_	_
11	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	LPS	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	viruses	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	other	_	ADJ	_	Degree=Pos	_	_	_	_
23	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	ability	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CMV	_	NOUN	_	Number=Sing	_	_	_	_
8	IE	_	NOUN	_	_	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	products	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	THP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	CMV	_	PROPN	_	Number=Sing	_	_	_	_
18	IE	_	NOUN	_	_	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	6	_	NUM	_	NumType=Card	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	control	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	CMV	_	PROPN	_	Number=Sing	_	_	_	_
16	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
17	early	_	ADJ	_	Degree=Pos	_	_	_	_
18	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CMV	_	PROPN	_	Number=Sing	_	_	_	_
4	IE	_	PROPN	_	_	_	_	_	_
5	genes	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	6	_	NUM	_	NumType=Card	_	_	_	_
10	chloramphenicol	_	NOUN	_	Number=Sing	_	_	_	_
11	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
12	transferase	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	CAT	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	6	_	NUM	_	NumType=Card	_	_	_	_
20	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
21	constructs	_	NOUN	_	Number=Plur	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	study	_	VERB	_	VerbForm=Inf	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	6	_	NUM	_	NumType=Card	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Interleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	6	_	NUM	_	NumType=Card	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	significantly	_	ADV	_	_	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	CMV	_	NOUN	_	Number=Sing	_	_	_	_
19	IE	_	NOUN	_	_	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	LPS	_	NOUN	_	Number=Sing	_	_	_	_
25	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	LPS	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	control	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Cytomegalovirus	_	PROPN	_	Number=Sing	_	_	_	_
2	IE	_	X	_	_	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	products	_	NOUN	_	Number=Plur	_	_	_	_
5	significantly	_	ADV	_	_	_	_	_	_
6	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	LPS	_	PROPN	_	Number=Sing	_	_	_	_
8	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	6	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	both	_	CCONJ	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	6	_	NUM	_	NumType=Card	_	_	_	_
20	CAT	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	6	_	NUM	_	NumType=Card	_	_	_	_
25	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
26	assays	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	deletion	_	NOUN	_	Number=Sing	_	_	_	_
3	construct	_	NOUN	_	Number=Sing	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	missing	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	region	_	NOUN	_	Number=Sing	_	_	_	_
19	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	continued	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	increase	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	6	_	NUM	_	NumType=Card	_	_	_	_
27	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	LPS	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	CMV	_	PROPN	_	Number=Sing	_	_	_	_
34	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSION	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Cytomegalovirus	_	PROPN	_	Number=Sing	_	_	_	_
4	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
5	early	_	ADJ	_	Degree=Pos	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	products	_	NOUN	_	Number=Plur	_	_	_	_
8	significantly	_	ADV	_	_	_	_	_	_
9	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	6	_	NUM	_	NumType=Card	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	LPS	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	increase	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	absence	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
16	response	_	NOUN	_	Number=Sing	_	_	_	_
17	region	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	area	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	6	_	NUM	_	NumType=Card	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	responsive	_	ADJ	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	TNF	_	PROPN	_	Number=Sing	_	_	_	_
34	alpha	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	cyclic	_	NOUN	_	Number=Sing	_	_	_	_
37	amp	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
41	12	_	NUM	_	NumType=Card	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	myristate	_	NOUN	_	Number=Sing	_	_	_	_
44	13	_	NUM	_	NumType=Card	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	acetate	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	CMV	_	NOUN	_	Number=Sing	_	_	_	_
5	IE	_	NOUN	_	_	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	products	_	NOUN	_	Number=Plur	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	6	_	NUM	_	NumType=Card	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	play	_	VERB	_	VerbForm=Inf	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	important	_	ADJ	_	Degree=Pos	_	_	_	_
18	role	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	immune	_	ADJ	_	Degree=Pos	_	_	_	_
21	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	states	_	NOUN	_	Number=Plur	_	_	_	_
23	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	CMV	_	PROPN	_	Number=Sing	_	_	_	_
26	infection	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002187	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Costimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	requirement	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	NF	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
12	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	delivered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	TCR	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	auxiliary	_	ADJ	_	Degree=Pos	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	CD28	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	participate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	among	_	ADP	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	like	_	ADJ	_	Degree=Pos	_	_	_	_
20	factors	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	PROPN	_	Number=Sing	_	_	_	_
25	B.	_	PROPN	_	Number=Sing	_	_	_	_
26	Protein	_	PROPN	_	Number=Sing	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	important	_	ADJ	_	Degree=Pos	_	_	_	_
31	role	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	regulation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
37	two	_	NUM	_	NumType=Card	_	_	_	_
38	factors	_	NOUN	_	Number=Plur	_	_	_	_
39	:	_	PUNCT	_	_	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	1	_	X	_	_	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
44	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	transactivating	_	NOUN	_	Number=Sing	_	_	_	_
47	capacity	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	AP	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	1	_	NUM	_	NumType=Card	_	_	_	_
53	protein	_	NOUN	_	Number=Sing	_	_	_	_
54	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
55	;	_	PUNCT	_	_	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	(	_	PUNCT	_	_	_	_	_	_
58	2	_	X	_	_	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
61	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
62	involved	_	ADJ	_	Degree=Pos	_	_	_	_
63	in	_	ADP	_	_	_	_	_	_
64	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
65	release	_	NOUN	_	Number=Sing	_	_	_	_
66	of	_	ADP	_	_	_	_	_	_
67	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
68	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
69	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
70	,	_	PUNCT	_	_	_	_	_	_
71	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
72	kappa	_	VERB	_	Number=Sing	_	_	_	_
73	B	_	PROPN	_	Number=Sing	_	_	_	_
74	,	_	PUNCT	_	_	_	_	_	_
75	from	_	ADP	_	_	_	_	_	_
76	NF	_	PROPN	_	Number=Sing	_	_	_	_
77	-	_	PUNCT	_	_	_	_	_	_
78	kappa	_	PROPN	_	Number=Sing	_	_	_	_
79	B	_	NOUN	_	Number=Sing	_	_	_	_
80	,	_	PUNCT	_	_	_	_	_	_
81	allowing	_	VERB	_	VerbForm=Ger	_	_	_	_
82	translocation	_	NOUN	_	Number=Sing	_	_	_	_
83	of	_	ADP	_	_	_	_	_	_
84	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
85	latter	_	ADJ	_	Degree=Pos	_	_	_	_
86	into	_	ADP	_	_	_	_	_	_
87	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
88	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
89	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	recently	_	ADV	_	_	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	both	_	DET	_	_	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	processes	_	NOUN	_	Number=Plur	_	_	_	_
9	require	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
11	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	two	_	NUM	_	NumType=Card	_	_	_	_
13	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
14	events	_	NOUN	_	Number=Plur	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	essentially	_	ADV	_	_	_	_	_	_
17	similar	_	ADJ	_	Degree=Pos	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	According	_	VERB	_	VerbForm=Ger	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	however	_	ADV	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	kinases	_	NOUN	_	Number=Plur	_	_	_	_
10	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	two	_	NUM	_	NumType=Card	_	_	_	_
14	processes	_	NOUN	_	Number=Plur	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
17	entities	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	TPCK	_	PROPN	_	Number=Sing	_	_	_	_
3	inhibits	_	VERB	_	Number=Plur	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	kappa	_	PROPN	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	consequently	_	ADV	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	PROPN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
21	markedly	_	ADV	_	_	_	_	_	_
22	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	JNK	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	MAP	_	NOUN	_	Number=Sing	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	related	_	ADJ	_	Degree=Pos	_	_	_	_
33	kinase	_	NOUN	_	Number=Sing	_	_	_	_
34	that	_	PRON	_	PronType=Rel	_	_	_	_
35	phosphorylates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
38	domain	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	c	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	Jun	_	PROPN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	therefore	_	ADV	_	_	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	propose	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	scheme	_	NOUN	_	Number=Sing	_	_	_	_
9	presented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	FIGURE	_	NOUN	_	Number=Sing	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
15	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Costimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
9	pathway	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	simultaneous	_	ADJ	_	Degree=Pos	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	two	_	NUM	_	NumType=Card	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factors	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	AP	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	PROPN	_	Number=Sing	_	_	_	_
29	B.	_	PROPN	_	Number=Sing	_	_	_	_
30	Integration	_	PROPN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	signals	_	NOUN	_	Number=Plur	_	_	_	_
34	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	TCR	_	PROPN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	CD28	_	PROPN	_	Number=Sing	_	_	_	_
39	engagement	_	NOUN	_	Number=Sing	_	_	_	_
40	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	along	_	ADP	_	_	_	_	_	_
42	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
43	pathway	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	which	_	PRON	_	PronType=Rel	_	_	_	_
46	then	_	ADV	_	PronType=Dem	_	_	_	_
47	bifurcates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
48	to	_	ADP	_	_	_	_	_	_
49	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
50	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
51	kappa	_	VERB	_	Number=Sing	_	_	_	_
52	B	_	PROPN	_	Number=Sing	_	_	_	_
53	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
54	and	_	CCONJ	_	_	_	_	_	_
55	NF	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	kappa	_	NOUN	_	Number=Sing	_	_	_	_
58	B	_	NOUN	_	Number=Sing	_	_	_	_
59	activation	_	NOUN	_	Number=Sing	_	_	_	_
60	on	_	ADP	_	_	_	_	_	_
61	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
62	one	_	NUM	_	NumType=Card	_	_	_	_
63	hand	_	NOUN	_	Number=Sing	_	_	_	_
64	,	_	PUNCT	_	_	_	_	_	_
65	and	_	CCONJ	_	_	_	_	_	_
66	JNK	_	PROPN	_	Number=Sing	_	_	_	_
67	activation	_	NOUN	_	Number=Sing	_	_	_	_
68	and	_	CCONJ	_	_	_	_	_	_
69	c	_	NOUN	_	Number=Sing	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	Jun	_	PROPN	_	Number=Sing	_	_	_	_
72	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
73	on	_	ADP	_	_	_	_	_	_
74	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
75	other	_	ADJ	_	Degree=Pos	_	_	_	_
76	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	currently	_	ADV	_	_	_	_	_	_
4	engaged	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	SCONJ	_	_	_	_	_	_
6	defining	_	VERB	_	VerbForm=Ger	_	_	_	_
7	where	_	ADV	_	PronType=Int	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	signals	_	NOUN	_	Number=Plur	_	_	_	_
11	integrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	along	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1/NF	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	pathway	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002190	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Barr	_	PROPN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
7	product	_	NOUN	_	Number=Sing	_	_	_	_
8	latent	_	ADJ	_	Degree=Pos	_	_	_	_
9	membrane	_	NOUN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	engages	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	tumor	_	NOUN	_	Number=Sing	_	_	_	_
15	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	death	_	NOUN	_	Number=Sing	_	_	_	_
21	domain	_	NOUN	_	Number=Sing	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
25	B	_	PROPN	_	Number=Sing	_	_	_	_
26	lymphocyte	_	NOUN	_	Degree=Pos	_	_	_	_
27	growth	_	NOUN	_	Number=Sing	_	_	_	_
28	transformation	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Barr	_	PROPN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	latent	_	VERB	_	Degree=Pos	_	_	_	_
7	membrane	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	essential	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transformation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	into	_	ADP	_	_	_	_	_	_
22	lymphoblastoid	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	lines	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	model	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	constitutively	_	ADV	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	DET	_	PronType=Rel	_	_	_	_
16	transduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	signals	_	NOUN	_	Number=Plur	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	transformation	_	NOUN	_	Number=Sing	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	carboxyl	_	ADJ	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
25	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
26	tail	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	transformation	_	NOUN	_	Number=Sing	_	_	_	_
3	effector	_	NOUN	_	Number=Sing	_	_	_	_
4	site	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	TES1	_	NUM	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	within	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	membrane	_	NOUN	_	Number=Sing	_	_	_	_
13	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
14	45	_	NUM	_	NumType=Card	_	_	_	_
15	residues	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
19	tail	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	constitutively	_	ADV	_	_	_	_	_	_
22	engages	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	tumor	_	NOUN	_	Number=Sing	_	_	_	_
24	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	factors	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Signals	_	NOUN	_	Number=Plur	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	TES1	_	PROPN	_	Number=Sing	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	drive	_	VERB	_	VerbForm=Inf	_	_	_	_
8	initial	_	ADJ	_	Degree=Pos	_	_	_	_
9	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	most	_	ADV	_	_	_	_	_	_
18	lymphoblastoid	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	virus	_	NOUN	_	Number=Sing	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	express	_	VERB	_	VerbForm=Inf	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	155	_	NUM	_	NumType=Card	_	_	_	_
30	residues	_	NOUN	_	Number=Plur	_	_	_	_
31	beyond	_	ADP	_	_	_	_	_	_
32	TES1	_	PROPN	_	Number=Sing	_	_	_	_
33	fail	_	VERB	_	Number=Sing	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	grow	_	VERB	_	VerbForm=Inf	_	_	_	_
36	as	_	ADP	_	_	_	_	_	_
37	long	_	ADJ	_	Degree=Pos	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	term	_	NOUN	_	Number=Sing	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	lines	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	mutating	_	VERB	_	VerbForm=Ger	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	tyrosines	_	NOUN	_	Number=Plur	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	isoleucine	_	NOUN	_	Number=Sing	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	carboxyl	_	NOUN	_	Number=Sing	_	_	_	_
14	end	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
18	tail	_	NOUN	_	Number=Sing	_	_	_	_
19	cripples	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	ability	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	EBV	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	cause	_	VERB	_	VerbForm=Inf	_	_	_	_
26	lymphoblastoid	_	ADJ	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	outgrowth	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	thereby	_	ADV	_	_	_	_	_	_
31	marking	_	VERB	_	VerbForm=Ger	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
34	transformation	_	NOUN	_	Number=Sing	_	_	_	_
35	effector	_	NOUN	_	Number=Sing	_	_	_	_
36	site	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	TES2	_	PROPN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	yeast	_	ADJ	_	Number=Sing	_	_	_	_
3	two	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
6	screen	_	NOUN	_	Number=Sing	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	TES2	_	PROPN	_	Number=Sing	_	_	_	_
9	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	including	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	tumor	_	NOUN	_	Number=Sing	_	_	_	_
15	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	death	_	NOUN	_	Number=Sing	_	_	_	_
21	domain	_	NOUN	_	Number=Sing	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	TRADD	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	TRADD	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	only	_	ADJ	_	Degree=Pos	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	interacted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	wild	_	ADJ	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	type	_	NOUN	_	Number=Sing	_	_	_	_
12	TES2	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	isoleucine	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	TES2	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	TRADD	_	PROPN	_	Number=Sing	_	_	_	_
2	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	wild	_	ADJ	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	not	_	ADV	_	_	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	isoleucine	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	TRADD	_	NOUN	_	Number=Sing	_	_	_	_
21	constitutively	_	ADV	_	_	_	_	_	_
22	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	EBV	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	assays	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	TRADD	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	TES2	_	PROPN	_	Number=Sing	_	_	_	_
8	synergistically	_	ADV	_	_	_	_	_	_
9	mediated	_	VERB	_	Degree=Pos	_	_	_	_
10	high	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	level	_	NOUN	_	Number=Sing	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
6	appropriates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	TRADD	_	VERB	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	enable	_	VERB	_	VerbForm=Inf	_	_	_	_
10	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
11	long	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	term	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphoblastoid	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	outgrowth	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	High	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	level	_	NOUN	_	Number=Sing	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	critical	_	ADJ	_	Degree=Pos	_	_	_	_
14	component	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	long	_	ADJ	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	term	_	NOUN	_	Number=Sing	_	_	_	_
19	outgrowth	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002194	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Antisense	_	ADJ	_	Degree=Pos	_	_	_	_
2	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	p65	_	NUM	_	Number=Sing	_	_	_	_
6	subunit	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	block	_	NOUN	_	Number=Sing	_	_	_	_
13	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	alter	_	VERB	_	_	_	_	_	_
17	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
18	properties	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	differentiated	_	ADJ	_	Degree=Pos	_	_	_	_
21	HL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	60	_	NUM	_	NumType=Card	_	_	_	_
24	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	pleiotropic	_	ADJ	_	Degree=Pos	_	_	_	_
8	regulator	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	variety	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	implicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	injury	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	function	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	attributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	coordinated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	subunits	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	distinct	_	VERB	_	VerbForm=Inf	_	_	_	_
19	regions	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	elements	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	numerous	_	ADJ	_	Degree=Pos	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	including	_	VERB	_	VerbForm=Ger	_	_	_	_
29	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	growth	_	NOUN	_	Number=Sing	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	receptors	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
37	molecules	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Antisense	_	ADJ	_	Degree=Pos	_	_	_	_
2	phosphorothioate	_	NOUN	_	Number=Sing	_	_	_	_
3	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	p50	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	p65	_	NUM	_	Number=Sing	_	_	_	_
9	subunits	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	complex	_	NOUN	_	Number=Sing	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	define	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	physiologic	_	ADJ	_	Degree=Pos	_	_	_	_
23	role	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	SCONJ	_	_	_	_	_	_
29	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	reduction	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	p65	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	treatment	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	phosphorothioate	_	ADJ	_	Degree=Pos	_	_	_	_
15	antisense	_	NOUN	_	Number=Sing	_	_	_	_
16	oligodeoxynucleotide	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	reduction	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
7	changes	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	dimethyl	_	ADJ	_	Degree=Pos	_	_	_	_
14	sulfoxide	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	differentiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	HL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	60	_	NUM	_	NumType=Card	_	_	_	_
20	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
25	13	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	acetate	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	TPA	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	reduction	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
11	integrin	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	surface	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	p65	_	PROPN	_	Number=Sing	_	_	_	_
5	antisense	_	ADJ	_	Number=Sing	_	_	_	_
6	oligomer	_	NOUN	_	Number=Sing	_	_	_	_
7	effectively	_	ADV	_	_	_	_	_	_
8	abolished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	CD11b	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	formyl	_	ADJ	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	met	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	leu	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	phe	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	TPA	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	p65	_	PROPN	_	Number=Sing	_	_	_	_
5	antisense	_	ADJ	_	Degree=Pos	_	_	_	_
6	phosphorothioate	_	ADJ	_	Number=Sing	_	_	_	_
7	oligodeoxynucleotide	_	NOUN	_	Number=Sing	_	_	_	_
8	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	no	_	DET	_	_	_	_	_	_
10	significant	_	ADJ	_	Degree=Pos	_	_	_	_
11	effect	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
17	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
18	intermediates	_	NOUN	_	Number=Plur	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	phagocytosis	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	antisense	_	ADJ	_	Degree=Pos	_	_	_	_
6	oligomers	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	p65	_	NOUN	_	Number=Sing	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	define	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	pathways	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002196	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	ETS	_	NOUN	_	Number=Sing	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	third	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
11	intron	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	TNF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	PROPN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	third	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
9	intron	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	tumor	_	NOUN	_	Number=Sing	_	_	_	_
12	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	alpha	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	reporter	_	NOUN	_	Number=Sing	_	_	_	_
3	construct	_	VERB	_	Number=Sing	_	_	_	_
4	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	5	_	NUM	_	NumType=Card	_	_	_	_
7	'-	_	PUNCT	_	_	_	_	_	_
8	flanking	_	VERB	_	Number=Sing	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	mouse	_	NOUN	_	Number=Sing	_	_	_	_
13	TNF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	displayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	weak	_	ADJ	_	Degree=Pos	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	when	_	ADV	_	PronType=Int	_	_	_	_
21	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	into	_	ADP	_	_	_	_	_	_
23	RAW264.7	_	PROPN	_	Number=Sing	_	_	_	_
24	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	like	_	ADP	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	third	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	intron	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	construct	_	NOUN	_	Number=Sing	_	_	_	_
14	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	CAT	_	NOUN	_	Number=Sing	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	eliminated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	if	_	SCONJ	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	conserved	_	VERB	_	Degree=Pos	_	_	_	_
8	20	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	bp	_	NOUN	_	Number=Sing	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	removed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	intron	_	NOUN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	if	_	SCONJ	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	negative	_	ADJ	_	Degree=Pos	_	_	_	_
23	ets	_	NOUN	_	Number=Plur	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	co	_	X	_	_	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	reporter	_	NOUN	_	Number=Sing	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	site	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	destroyed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	potential	_	ADJ	_	Degree=Pos	_	_	_	_
8	ets	_	NOUN	_	Number=Plur	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	VerbForm=Ger	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	major	_	ADJ	_	Degree=Pos	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	bound	_	VERB	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	GABP	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	supershift	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	competition	_	NOUN	_	Number=Sing	_	_	_	_
19	analysis	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	RAW264.7	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	however	_	ADV	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	bone	_	ADJ	_	Number=Sing	_	_	_	_
14	marrow	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
18	binding	_	VERB	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	interferon	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	gamma	_	NOUN	_	Number=Sing	_	_	_	_
27	inducible	_	ADJ	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	imply	_	VERB	_	VerbForm=Inf	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	ets	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factors	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002199	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Xenogeneic	_	ADJ	_	Degree=Pos	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	serum	_	NOUN	_	Number=Sing	_	_	_	_
4	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
6	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	porcine	_	NOUN	_	VerbForm=Inf	_	_	_	_
9	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
10	under	_	ADP	_	_	_	_	_	_
11	flow	_	NOUN	_	Number=Sing	_	_	_	_
12	conditions	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	possibly	_	ADV	_	_	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B.	_	PROPN	_	Number=Sing	_	_	_	_
26	Endothelial	_	PROPN	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
31	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
32	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
35	feature	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	discordant	_	ADJ	_	Degree=Pos	_	_	_	_
38	xenograft	_	NOUN	_	Number=Sing	_	_	_	_
39	rejection	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	evaluated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	whether	_	SCONJ	_	_	_	_	_	_
5	xenogeneic	_	ADJ	_	Degree=Pos	_	_	_	_
6	serum	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	source	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	xenoreactive	_	ADJ	_	Degree=Pos	_	_	_	_
13	natural	_	ADJ	_	Degree=Pos	_	_	_	_
14	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	complement	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	consequent	_	ADJ	_	Degree=Pos	_	_	_	_
24	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
25	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
26	under	_	ADP	_	_	_	_	_	_
27	flow	_	NOUN	_	Number=Sing	_	_	_	_
28	conditions	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Porcine	_	ADJ	_	Degree=Pos	_	_	_	_
2	aortic	_	ADJ	_	Degree=Pos	_	_	_	_
3	endothelial	_	NOUN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	PAEC	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	incubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	hr	_	NOUN	_	Number=Sing	_	_	_	_
13	30	_	NUM	_	NumType=Card	_	_	_	_
14	min	_	NOUN	_	Number=Plur	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	5	_	NUM	_	NumType=Card	_	_	_	_
17	hr	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	10	_	NUM	_	NumType=Card	_	_	_	_
20	%	_	SYM	_	Number=Sing	_	_	_	_
21	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
22	porcine	_	NOUN	_	Number=Sing	_	_	_	_
23	serum	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	control	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	10	_	NUM	_	NumType=Card	_	_	_	_
29	%	_	SYM	_	Number=Sing	_	_	_	_
30	xenogeneic	_	ADJ	_	Degree=Pos	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	serum	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	then	_	ADV	_	PronType=Dem	_	_	_	_
35	perfused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	total	_	ADJ	_	Degree=Pos	_	_	_	_
38	human	_	ADJ	_	Degree=Pos	_	_	_	_
39	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	parallel	_	ADJ	_	Degree=Pos	_	_	_	_
43	plate	_	NOUN	_	Number=Sing	_	_	_	_
44	flow	_	NOUN	_	Number=Sing	_	_	_	_
45	chamber	_	NOUN	_	Number=Sing	_	_	_	_
46	under	_	ADP	_	_	_	_	_	_
47	laminar	_	ADJ	_	Degree=Pos	_	_	_	_
48	flow	_	NOUN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	1.5	_	NUM	_	NumType=Card	_	_	_	_
51	dynes	_	NOUN	_	Number=Plur	_	_	_	_
52	/	_	SYM	_	_	_	_	_	_
53	cm2	_	NOUN	_	Number=Sing	_	_	_	_
54	)	_	PUNCT	_	_	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Adherent	_	ADJ	_	Degree=Pos	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	counted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	digital	_	ADJ	_	Degree=Pos	_	_	_	_
7	image	_	NOUN	_	Number=Sing	_	_	_	_
8	analysis	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Xenogeneic	_	ADJ	_	Degree=Pos	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	serum	_	NOUN	_	Number=Sing	_	_	_	_
4	significantly	_	ADV	_	_	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	P	_	NOUN	_	Number=Sing	_	_	_	_
7	<	_	PUNCT	_	_	_	_	_	_
8	0.01	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	number	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	adherent	_	ADJ	_	Degree=Pos	_	_	_	_
15	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	as	_	SCONJ	_	_	_	_	_	_
17	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	porcine	_	NOUN	_	Number=Sing	_	_	_	_
20	serum	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	similar	_	ADJ	_	Degree=Pos	_	_	_	_
3	adhesive	_	ADJ	_	Degree=Pos	_	_	_	_
4	response	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	elicited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	100	_	NUM	_	NumType=Card	_	_	_	_
12	U/ml	_	SYM	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	one	_	NUM	_	NumType=Card	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	most	_	ADV	_	_	_	_	_	_
19	potent	_	ADJ	_	Degree=Pos	_	_	_	_
20	inducers	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	adhesive	_	ADJ	_	Number=Sing	_	_	_	_
25	properties	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	here	_	ADV	_	PronType=Dem	_	_	_	_
28	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	as	_	ADP	_	_	_	_	_	_
30	positive	_	ADJ	_	Degree=Pos	_	_	_	_
31	control	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	elucidate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	possible	_	ADJ	_	Degree=Pos	_	_	_	_
6	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
7	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
8	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	xenogeneic	_	ADJ	_	Degree=Pos	_	_	_	_
13	serum	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	focussed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	PROPN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	central	_	ADJ	_	Degree=Pos	_	_	_	_
27	regulator	_	NOUN	_	Number=Sing	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	induction	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	different	_	ADJ	_	Degree=Pos	_	_	_	_
33	genes	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	including	_	VERB	_	VerbForm=Ger	_	_	_	_
36	adhesive	_	ADJ	_	Degree=Pos	_	_	_	_
37	molecules	_	NOUN	_	Number=Plur	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	chemoattractants	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	confocal	_	ADJ	_	Degree=Pos	_	_	_	_
3	fluorescence	_	NOUN	_	Number=Sing	_	_	_	_
4	microscopy	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	positive	_	ADJ	_	Degree=Pos	_	_	_	_
10	staining	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	PROPN	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	p65	_	NUM	_	Number=Sing	_	_	_	_
18	subunit	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	PAEC	_	PROPN	_	Number=Sing	_	_	_	_
25	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	hr	_	NOUN	_	Number=Sing	_	_	_	_
29	30	_	NUM	_	NumType=Card	_	_	_	_
30	min	_	NOUN	_	Number=Plur	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	human	_	ADJ	_	Degree=Pos	_	_	_	_
33	serum	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	which	_	PRON	_	PronType=Rel	_	_	_	_
36	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kappa	_	PROPN	_	Number=Sing	_	_	_	_
40	B	_	NOUN	_	Number=Sing	_	_	_	_
41	activation	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
44	setting	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	variance	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	PAEC	_	PROPN	_	Number=Sing	_	_	_	_
6	incubated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
10	serum	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	strictly	_	ADV	_	_	_	_	_	_
18	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	PAEC	_	PROPN	_	Number=Sing	_	_	_	_
4	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	xenogeneic	_	ADJ	_	Degree=Pos	_	_	_	_
7	serum	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
15	pyrrolidinedithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	PDTC	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	25	_	NUM	_	NumType=Card	_	_	_	_
20	microM	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	tosyl	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	phechloromethylketone	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	TPCK	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	25	_	NUM	_	NumType=Card	_	_	_	_
30	microM	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	significantly	_	ADV	_	_	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	P	_	NOUN	_	Number=Sing	_	_	_	_
35	<	_	PUNCT	_	_	_	_	_	_
36	0.01	_	NUM	_	NumType=Card	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
40	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	respect	_	NOUN	_	Number=Sing	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	PAEC	_	PROPN	_	Number=Sing	_	_	_	_
45	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	with	_	ADP	_	_	_	_	_	_
47	human	_	ADJ	_	Degree=Pos	_	_	_	_
48	serum	_	NOUN	_	Number=Sing	_	_	_	_
49	alone	_	ADV	_	_	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Findings	_	NOUN	_	Number=Plur	_	_	_	_
2	that	_	SCONJ	_	_	_	_	_	_
3	xenogeneic	_	ADJ	_	Degree=Pos	_	_	_	_
4	serum	_	NOUN	_	Number=Sing	_	_	_	_
5	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
9	interaction	_	NOUN	_	Number=Sing	_	_	_	_
10	possibly	_	ADV	_	_	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	PROPN	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	might	_	AUX	_	VerbForm=Fin	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	SCONJ	_	_	_	_	_	_
21	designing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	future	_	NOUN	_	Degree=Pos	_	_	_	_
23	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
24	strategies	_	NOUN	_	Number=Plur	_	_	_	_
25	aimed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	at	_	SCONJ	_	_	_	_	_	_
27	prolonging	_	VERB	_	VerbForm=Ger	_	_	_	_
28	xenograft	_	NOUN	_	Number=Sing	_	_	_	_
29	survival	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002202	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Barr	_	PROPN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	replicative	_	ADJ	_	Degree=Pos	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	during	_	ADP	_	_	_	_	_	_
9	de	_	PROPN	_	Number=Sing	_	_	_	_
10	novo	_	PROPN	_	Number=Sing	_	_	_	_
11	infection	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	simultaneous	_	ADJ	_	Degree=Pos	_	_	_	_
17	early	_	ADJ	_	Degree=Pos	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	BZLF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	repressor	_	NOUN	_	Number=Sing	_	_	_	_
26	RAZ	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Barr	_	PROPN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EBV	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	infect	_	VERB	_	VerbForm=Inf	_	_	_	_
12	B	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	others	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	EBV	_	PROPN	_	Number=Sing	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	infect	_	VERB	_	VerbForm=Inf	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	subset	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Infection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	appearance	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	linear	_	ADJ	_	Number=Sing	_	_	_	_
11	EBV	_	PROPN	_	Number=Sing	_	_	_	_
12	genome	_	NOUN	_	Number=Sing	_	_	_	_
13	within	_	ADP	_	_	_	_	_	_
14	8	_	NUM	_	NumType=Card	_	_	_	_
15	hr	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	infection	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Circularization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	EBV	_	PROPN	_	Number=Sing	_	_	_	_
5	genome	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	contrast	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	infection	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	B	_	ADJ	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	where	_	ADV	_	PronType=Rel	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	genome	_	NOUN	_	Number=Sing	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	circularize	_	VERB	_	VerbForm=Inf	_	_	_	_
16	within	_	ADP	_	_	_	_	_	_
17	24	_	NUM	_	NumType=Card	_	_	_	_
18	hr	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	infection	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	appearance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	BamHI	_	PROPN	_	Number=Sing	_	_	_	_
6	ZLF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	product	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	RT	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	PCR	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	within	_	ADP	_	_	_	_	_	_
22	8	_	NUM	_	NumType=Card	_	_	_	_
23	hr	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	infection	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	appearance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	novel	_	NOUN	_	Number=Sing	_	_	_	_
6	fusion	_	NOUN	_	Number=Sing	_	_	_	_
7	transcript	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	RAZ	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	comprised	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	regions	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	BZLF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	locus	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
24	BRLF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	locus	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	RT	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	PCR	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	Fp	_	PROPN	_	Number=Sing	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	rather	_	ADV	_	_	_	_	_	_
23	than	_	ADP	_	_	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	Cp	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	Wp	_	NOUN	_	Number=Sing	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	which	_	PRON	_	PronType=Rel	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	latently	_	ADV	_	_	_	_	_	_
35	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	B	_	ADJ	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Transcripts	_	NOUN	_	Number=Plur	_	_	_	_
2	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
3	gp350/220	_	NUM	_	NumType=Card	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	major	_	ADJ	_	Degree=Pos	_	_	_	_
7	coat	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	EBV	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	find	_	VERB	_	VerbForm=Inf	_	_	_	_
20	any	_	DET	_	_	_	_	_	_
21	evidence	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	LMP	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2A	_	NOUN	_	Number=Sing	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	EBER	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	loci	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	de	_	PROPN	_	Number=Sing	_	_	_	_
6	novo	_	X	_	Number=Sing	_	_	_	_
7	EBV	_	PROPN	_	Number=Sing	_	_	_	_
8	infection	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	differs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	infection	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	B	_	ADJ	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	main	_	ADJ	_	Degree=Pos	_	_	_	_
3	difference	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	no	_	DET	_	_	_	_	_	_
10	evidence	_	NOUN	_	Number=Sing	_	_	_	_
11	could	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	ever	_	ADV	_	_	_	_	_	_
18	circularizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Rather	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	EBV	_	PROPN	_	Number=Sing	_	_	_	_
4	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	linear	_	ADJ	_	Degree=Pos	_	_	_	_
8	configuration	_	NOUN	_	Number=Sing	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	replicative	_	ADJ	_	Degree=Pos	_	_	_	_
12	genes	_	NOUN	_	Number=Plur	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002203	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
2	messenger	_	NOUN	_	Number=Sing	_	_	_	_
3	up	_	ADP	_	_	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	androgen	_	NOUN	_	Degree=Pos	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	absent	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	androgen	_	NOUN	_	Number=Sing	_	_	_	_
15	insensitive	_	ADJ	_	Degree=Pos	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	prostatic	_	ADJ	_	Degree=Pos	_	_	_	_
18	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	lines	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	PC	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	DU	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	145	_	NUM	_	NumType=Card	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	theoretical	_	ADJ	_	Degree=Pos	_	_	_	_
3	pathway	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	androgen	_	NOUN	_	Degree=Pos	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	AR	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	via	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	element	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	CRE	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	present	_	VERB	_	Degree=Pos	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	region	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	-	_	SYM	_	_	_	_	_	_
31	508	_	NUM	_	NumType=Card	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	-	_	SYM	_	_	_	_	_	_
34	501	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	20	_	NUM	_	NumType=Card	_	_	_	_
3	h	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	8-	_	NUM	_	NumType=Card	_	_	_	_
8	bromo	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	AR	_	PROPN	_	Number=Sing	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	upregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	LNCaP	_	PROPN	_	Number=Sing	_	_	_	_
18	but	_	CCONJ	_	_	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	either	_	CCONJ	_	_	_	_	_	_
22	PC	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	DU	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	145	_	NUM	_	NumType=Card	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	lines	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	level	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	CRE	_	PROPN	_	Number=Sing	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	CREB	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	same	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	all	_	DET	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	lines	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	putative	_	ADJ	_	Degree=Pos	_	_	_	_
25	AR	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	CRE	_	NOUN	_	Number=Sing	_	_	_	_
28	forms	_	NOUN	_	Number=Plur	_	_	_	_
29	specific	_	ADJ	_	Degree=Pos	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	compatible	_	ADJ	_	Degree=Pos	_	_	_	_
32	protein	_	NOUN	_	Number=Sing	_	_	_	_
33	interactions	_	NOUN	_	Number=Plur	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	CREB	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	AR	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	via	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
11	messenger	_	NOUN	_	Number=Sing	_	_	_	_
12	pathway	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	lost	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	PC	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	DU	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	145	_	NUM	_	NumType=Card	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	lines	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	be	_	AUX	_	VerbForm=Inf	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	primary	_	ADJ	_	Degree=Pos	_	_	_	_
7	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	androgen	_	ADJ	_	Degree=Pos	_	_	_	_
10	insensitivity	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	prostate	_	ADJ	_	Number=Sing	_	_	_	_
13	cancer	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002213	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
4	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	signaling	_	NOUN	_	Number=Sing	_	_	_	_
6	pathways	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	CD34	_	PROPN	_	Number=Sing	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_
10	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	line	_	NOUN	_	Number=Sing	_	_	_	_
20	model	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	signals	_	NOUN	_	Number=Plur	_	_	_	_
3	that	_	DET	_	_	_	_	_	_
4	mediate	_	VERB	_	Degree=Pos	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	pluripotent	_	ADJ	_	Degree=Pos	_	_	_	_
8	hemopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
9	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	DC	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	largely	_	ADV	_	_	_	_	_	_
18	undefined	_	ADJ	_	Degree=Pos	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	C	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	PKC	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
16	ester	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	PMA	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	alone	_	ADV	_	_	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	specifically	_	ADV	_	_	_	_	_	_
23	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	primary	_	ADJ	_	Degree=Pos	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	CD34	_	NOUN	_	Number=Sing	_	_	_	_
29	+	_	SYM	_	_	_	_	_	_
30	hemopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
31	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	HPC	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	mature	_	VERB	_	VerbForm=Inf	_	_	_	_
38	DC	_	PROPN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
12	CSF	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	CD34	_	NOUN	_	Number=Sing	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	HPC	_	NOUN	_	Number=Sing	_	_	_	_
21	-->	_	PUNCT	_	_	_	_	_	_
22	DC	_	PROPN	_	Number=Sing	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	preferentially	_	ADV	_	_	_	_	_	_
26	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	PKC	_	PROPN	_	Number=Sing	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
4	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	signals	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
8	events	_	NOUN	_	Number=Plur	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	CD34	_	PROPN	_	Number=Sing	_	_	_	_
12	+	_	SYM	_	_	_	_	_	_

1	HPC	_	NOUN	_	Number=Sing	_	_	_	_
2	-->	_	PUNCT	_	_	_	_	_	_
3	DC	_	PROPN	_	Number=Sing	_	_	_	_
4	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	line	_	NOUN	_	Number=Sing	_	_	_	_
13	model	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	process	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CD34	_	NOUN	_	Number=Sing	_	_	_	_
3	+	_	SYM	_	_	_	_	_	_
4	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	line	_	NOUN	_	Number=Sing	_	_	_	_
7	KG1	_	PROPN	_	Number=Sing	_	_	_	_
8	differentiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	into	_	ADP	_	_	_	_	_	_
10	dendritic	_	NOUN	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	like	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
20	CSF	_	PROPN	_	Number=Sing	_	_	_	_
21	plus	_	CCONJ	_	_	_	_	_	_
22	TNF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	PMA	_	PROPN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	without	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	calcium	_	NOUN	_	Number=Sing	_	_	_	_
34	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
35	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	TNF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	alpha	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	with	_	ADP	_	_	_	_	_	_
44	different	_	ADJ	_	Degree=Pos	_	_	_	_
45	stimuli	_	NOUN	_	Degree=Pos	_	_	_	_
46	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
47	different	_	ADJ	_	Degree=Pos	_	_	_	_
48	aspects	_	NOUN	_	Number=Plur	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	process	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
2	DC	_	PROPN	_	Number=Sing	_	_	_	_
3	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	KG1	_	PROPN	_	Number=Sing	_	_	_	_
6	dendritic	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	like	_	ADJ	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	morphology	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	loosely	_	ADV	_	_	_	_	_	_
14	adherent	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	long	_	ADJ	_	Degree=Pos	_	_	_	_
18	neurite	_	NOUN	_	Number=Sing	_	_	_	_
19	processes	_	NOUN	_	Number=Plur	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	MHC	_	PROPN	_	Number=Sing	_	_	_	_
23	I+/	_	NUM	_	_	_	_	_	_
24	MHC	_	PROPN	_	Number=Sing	_	_	_	_
25	IIbright	_	NUM	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	CD83+/CD86+/CD14	_	NUM	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	surface	_	NOUN	_	Number=Sing	_	_	_	_

1	Ag	_	PROPN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	RelB	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	DC	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	CK1	_	PROPN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	DC	_	PROPN	_	Number=Sing	_	_	_	_
3	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
4	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	fluid	_	ADJ	_	Number=Sing	_	_	_	_
6	phase	_	NOUN	_	Number=Sing	_	_	_	_
7	macromolecule	_	NOUN	_	Number=Sing	_	_	_	_
8	uptake	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	FITC	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dextran	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	SCONJ	_	_	_	_	_	_
17	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Comparison	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	KG1	_	PROPN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	PMA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	unresponsive	_	ADJ	_	Degree=Pos	_	_	_	_
9	subline	_	NOUN	_	Number=Sing	_	_	_	_
10	KG1a	_	PROPN	_	Number=Sing	_	_	_	_
11	reveals	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	differences	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	receptors	_	NOUN	_	Number=Plur	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	;	_	PUNCT	_	_	_	_	_	_
22	PKC	_	PROPN	_	Number=Sing	_	_	_	_
23	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	beta	_	NOUN	_	Number=Sing	_	_	_	_
27	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	beta	_	NOUN	_	Number=Sing	_	_	_	_
30	II	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	mu	_	NOUN	_	Number=Sing	_	_	_	_
34	;	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	RelB	_	PROPN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
39	that	_	SCONJ	_	_	_	_	_	_
40	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
41	components	_	NOUN	_	Number=Plur	_	_	_	_
42	/	_	PUNCT	_	_	_	_	_	_
43	pathways	_	NOUN	_	Number=Plur	_	_	_	_
44	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
45	important	_	ADJ	_	Degree=Pos	_	_	_	_
46	for	_	ADP	_	_	_	_	_	_
47	DC	_	PROPN	_	Number=Sing	_	_	_	_
48	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	findings	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
10	ester	_	NOUN	_	Number=Sing	_	_	_	_
11	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	KG1	_	PROPN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	model	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	CD34	_	NOUN	_	Number=Sing	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_

1	HPC	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	DC	_	PROPN	_	Number=Sing	_	_	_	_
4	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	signaling	_	NOUN	_	Number=Sing	_	_	_	_
11	pathways	_	NOUN	_	Number=Plur	_	_	_	_
12	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	events	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	DC	_	PROPN	_	Number=Sing	_	_	_	_
17	lineage	_	NOUN	_	Number=Sing	_	_	_	_
18	commitment	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002219	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	vanadate	_	NOUN	_	Number=Sing	_	_	_	_
10	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
17	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Rapid	_	ADJ	_	Degree=Pos	_	_	_	_
2	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
3	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	key	_	ADJ	_	Degree=Pos	_	_	_	_
6	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
11	event	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	transduction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	signals	_	NOUN	_	Number=Plur	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	T-lymphocytes	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	role	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	PTPases	_	NOUN	_	Number=Plur	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	process	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	explored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	SCONJ	_	_	_	_	_	_
17	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	effects	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	powerful	_	ADJ	_	Degree=Pos	_	_	_	_
23	PTPase	_	NOUN	_	Number=Sing	_	_	_	_
24	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	vanadate	_	NOUN	_	Number=Sing	_	_	_	_
27	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	pervanadate	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	on	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	cascade	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	Jurkat	_	ADJ	_	Number=Sing	_	_	_	_
38	human	_	ADJ	_	Degree=Pos	_	_	_	_
39	leukaemic	_	ADJ	_	Number=Sing	_	_	_	_
40	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Pervanadate	_	NOUN	_	Number=Sing	_	_	_	_
2	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	kinases	_	NOUN	_	Number=Plur	_	_	_	_
8	lck	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	fyn	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	3	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	fold	_	VERB	_	Number=Sing	_	_	_	_
18	respectively	_	ADV	_	_	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
23	increase	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
26	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
29	proteins	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	notably	_	ADV	_	_	_	_	_	_
32	phospholipase	_	NOUN	_	Number=Sing	_	_	_	_
33	C	_	PROPN	_	Number=Sing	_	_	_	_
34	gamma	_	NOUN	_	Number=Sing	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	event	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	rise	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
12	+	_	SYM	_	_	_	_	_	_
13	concentration	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	influx	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	required	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	surface	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	CD45	_	NOUN	_	Number=Sing	_	_	_	_
9	PTPase	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	CD45	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
18	variants	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	CD45	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	negative	_	ADJ	_	Degree=Pos	_	_	_	_
6	variant	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	pervanadate	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
14	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	globally	_	ADV	_	_	_	_	_	_
17	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	some	_	DET	_	_	_	_	_	_
20	phosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
21	substrates	_	NOUN	_	Number=Plur	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	specifically	_	ADV	_	_	_	_	_	_
24	missing	_	VERB	_	Degree=Pos	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Pervanadate	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	c-fos	_	NOUN	_	Degree=Pos	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	as	_	ADV	_	_	_	_	_	_
15	well	_	ADV	_	Degree=Pos	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	several	_	ADJ	_	Degree=Pos	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	hallmarks	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	T-lymphocyte	_	ADJ	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	such	_	ADJ	_	Degree=Pos	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	surface	_	NOUN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	CD69	_	PROPN	_	Number=Sing	_	_	_	_
30	antigen	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	receptor	_	NOUN	_	Number=Sing	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	chain	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	CD25	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Pervanadate	_	NOUN	_	Number=Sing	_	_	_	_
2	synergized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	signals	_	NOUN	_	Number=Plur	_	_	_	_
5	delivered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
8	antigen	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	engagement	_	NOUN	_	Number=Sing	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
15	ester	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
18	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	production	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Pervanadate	_	PROPN	_	Number=Sing	_	_	_	_
2	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	as	_	SCONJ	_	_	_	_	_	_
9	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	increase	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	DNA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	thus	_	ADV	_	_	_	_	_	_
3	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	PTPases	_	NOUN	_	Number=Plur	_	_	_	_
6	play	_	VERB	_	VerbForm=Inf	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	negative	_	ADJ	_	Degree=Pos	_	_	_	_
13	regulation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	signal	_	ADJ	_	Number=Sing	_	_	_	_
16	transduction	_	NOUN	_	Number=Sing	_	_	_	_
17	culminating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	T-lymphocyte	_	ADJ	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
9	per	_	ADP	_	_	_	_	_	_
10	se	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	complete	_	ADJ	_	Degree=Pos	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	programme	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002221	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Relationship	_	NOUN	_	Number=Sing	_	_	_	_
2	between	_	ADP	_	_	_	_	_	_
3	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
4	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
8	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	EBV	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	lymphoblastoid	_	ADJ	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	EBV	_	PROPN	_	Number=Sing	_	_	_	_
13	transformation	_	NOUN	_	Number=Sing	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	stably	_	ADV	_	_	_	_	_	_
18	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
20	into	_	ADP	_	_	_	_	_	_
21	lymphoblastoid	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	clones	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	loss	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	transgenic	_	ADJ	_	Number=Sing	_	_	_	_
23	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	latency	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	immunocytochemistry	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	surface	_	NOUN	_	Number=Sing	_	_	_	_
4	markers	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	intracytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
7	content	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	cycle	_	NOUN	_	Number=Sing	_	_	_	_
12	analysis	_	NOUN	_	Number=Sing	_	_	_	_
13	after	_	ADP	_	_	_	_	_	_
14	BrdU	_	PROPN	_	Number=Sing	_	_	_	_
15	incorporation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	DNA	_	PROPN	_	Number=Sing	_	_	_	_
18	staining	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	propidium	_	NOUN	_	Number=Sing	_	_	_	_
21	iodide	_	NOUN	_	Number=Sing	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	flow	_	NOUN	_	Number=Sing	_	_	_	_
26	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Percentage	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	situ	_	NOUN	_	Number=Sing	_	_	_	_
11	labelling	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	strand	_	NOUN	_	Number=Sing	_	_	_	_
15	breaks	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	significative	_	ADJ	_	Degree=Pos	_	_	_	_
3	changes	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	EBV	_	PROPN	_	Number=Sing	_	_	_	_
6	latency	_	NOUN	_	Number=Sing	_	_	_	_
7	nor	_	CCONJ	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	surface	_	NOUN	_	Number=Sing	_	_	_	_
11	marker	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	intracytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
5	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	strongly	_	ADV	_	_	_	_	_	_
9	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	clones	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	30	_	NUM	_	NumType=Card	_	_	_	_
4	%	_	SYM	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
7	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
11	after	_	ADP	_	_	_	_	_	_
12	8	_	NUM	_	NumType=Card	_	_	_	_
13	h	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
16	treatment	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	correlated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	strong	_	ADJ	_	Degree=Pos	_	_	_	_
6	reduction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	BrdU	_	PROPN	_	Number=Sing	_	_	_	_
9	incorporation	_	NOUN	_	Number=Sing	_	_	_	_
10	after	_	ADP	_	_	_	_	_	_
11	24	_	NUM	_	NumType=Card	_	_	_	_
12	h	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
15	treatment	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	non	_	X	_	_	_	_	_	_
7	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	control	_	NOUN	_	Number=Sing	_	_	_	_
16	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	could	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	one	_	NUM	_	NumType=Card	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	targets	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	EBV	_	PROPN	_	Number=Sing	_	_	_	_
20	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	protects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	EBV	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
34	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	which	_	PRON	_	PronType=Rel	_	_	_	_
39	may	_	AUX	_	VerbForm=Fin	_	_	_	_
40	favour	_	VERB	_	VerbForm=Inf	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
43	effect	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
46	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002228	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Involvement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	N	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	terminal	_	ADJ	_	Number=Sing	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	mineralocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	hormone	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	domain	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	agonist	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	antagonist	_	ADJ	_	Number=Sing	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	as	_	SCONJ	_	_	_	_	_	_
23	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	new	_	ADJ	_	Degree=Pos	_	_	_	_
27	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
28	antibody	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	gain	_	VERB	_	VerbForm=Inf	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	better	_	ADJ	_	Degree=Cmp	_	_	_	_
5	understanding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	mineralocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	hMR	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
21	developed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	new	_	ADJ	_	Degree=Pos	_	_	_	_
24	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
25	antibody	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	mAb	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	raised	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	against	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	hormone	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	binding	_	VERB	_	Number=Sing	_	_	_	_
35	domain	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	HBD	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	purpose	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	mice	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	immunized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	fusion	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	including	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	Thr729	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	Lys984	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	hMR	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	ELISA	_	PROPN	_	Number=Sing	_	_	_	_
3	screening	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	mAb	_	PROPN	_	Number=Sing	_	_	_	_
6	18C7	_	NUM	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	selected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	specificity	_	NOUN	_	Number=Sing	_	_	_	_
12	towards	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	HBD	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	antibody	_	NOUN	_	Number=Sing	_	_	_	_
3	recognized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	denatured	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	native	_	ADJ	_	Degree=Pos	_	_	_	_
9	MR	_	NOUN	_	Number=Sing	_	_	_	_
10	forms	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	as	_	ADV	_	_	_	_	_	_
13	well	_	ADV	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	hetero	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	oligomeric	_	ADJ	_	Degree=Pos	_	_	_	_
19	MR	_	NOUN	_	Number=Sing	_	_	_	_
20	form	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	MR	_	PROPN	_	Number=Sing	_	_	_	_
25	state	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	several	_	ADJ	_	Degree=Pos	_	_	_	_
4	HBD	_	ADJ	_	Number=Sing	_	_	_	_
5	subfragments	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	mAb	_	NOUN	_	Number=Sing	_	_	_	_
9	18C7	_	NUM	_	NumType=Card	_	_	_	_
10	epitope	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	N	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	terminal	_	ADJ	_	Number=Sing	_	_	_	_
18	region	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	HBD	_	PROPN	_	Number=Sing	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	Thr729	_	PROPN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	Leu765	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	then	_	ADV	_	PronType=Dem	_	_	_	_
3	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	antibody	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	aldosterone	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	hMR	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	18C7	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	incubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	liganded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	MR	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	able	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	partly	_	ADV	_	_	_	_	_	_
14	displace	_	VERB	_	VerbForm=Inf	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	20	_	NUM	_	NumType=Card	_	_	_	_
17	%	_	SYM	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	hormone	_	NOUN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	18C7	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	incubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	MR	_	PROPN	_	Number=Sing	_	_	_	_
7	before	_	ADP	_	_	_	_	_	_
8	aldosterone	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	antibody	_	NOUN	_	Number=Sing	_	_	_	_
14	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	75	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	SYM	_	_	_	_	_	_
17	80	_	NUM	_	NumType=Card	_	_	_	_
18	%	_	SYM	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	18C7	_	NUM	_	NumType=Card	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	similar	_	ADJ	_	Degree=Pos	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	hormones	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	sucrose	_	ADJ	_	Number=Sing	_	_	_	_
3	gradient	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	simultaneous	_	ADJ	_	Degree=Pos	_	_	_	_
8	presence	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	kinds	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	complexes	_	NOUN	_	Number=Plur	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	steroid	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	MR	_	NOUN	_	Number=Sing	_	_	_	_
20	complex	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	antibody	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	MR	_	NOUN	_	Number=Sing	_	_	_	_
26	complex	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
3	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	proteins	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	especially	_	ADV	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	heat	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	shock	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	hsp90	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	cross	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	hMR	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	dimethylpimelimidate	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	18C7	_	NUM	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	still	_	ADV	_	_	_	_	_	_
28	able	_	ADJ	_	Degree=Pos	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	react	_	VERB	_	VerbForm=Inf	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	receptor	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	epitope	_	NOUN	_	Number=Sing	_	_	_	_
7	recognized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	18C7	_	NUM	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	directly	_	ADV	_	_	_	_	_	_
12	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	hormone	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	lack	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	steroid	_	ADJ	_	Degree=Pos	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	HBD	_	ADJ	_	Number=Sing	_	_	_	_
8	mutants	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	Thr729	_	PROPN	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	Leu765	_	PROPN	_	Number=Sing	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	deleted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	[	_	PUNCT	_	_	_	_	_	_
17	Jalaguier	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	Mesnier	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	Leger	_	PROPN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	Auzou	_	PROPN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	1996	_	NUM	_	NumType=Card	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	J.Steroid	_	PROPN	_	Number=Sing	_	_	_	_
28	Biochem.Mol.Biol.57	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	43-50	_	NUM	_	NumType=Card	_	_	_	_
31	]	_	PUNCT	_	_	_	_	_	_
32	supports	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
34	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	ADP	_	_	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	similar	_	ADJ	_	Degree=Pos	_	_	_	_
5	behaviours	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	aldosterone	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	N-terminal	_	PROPN	_	Number=Sing	_	_	_	_
16	Thr729	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	Leu765	_	PROPN	_	Number=Sing	_	_	_	_
19	region	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	HBD	_	PROPN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	similarly	_	ADV	_	_	_	_	_	_
25	involved	_	ADJ	_	Degree=Pos	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	both	_	DET	_	_	_	_	_	_
31	hormones	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002230	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	High	_	ADJ	_	Degree=Pos	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	weight	_	NOUN	_	Number=Sing	_	_	_	_
4	dextran	_	PROPN	_	Number=Sing	_	_	_	_
5	sulfate	_	NOUN	_	Number=Sing	_	_	_	_
6	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	sulfated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
6	polysaccharides	_	NOUN	_	Number=Plur	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	mimic	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	action	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	common	_	ADJ	_	Degree=Pos	_	_	_	_
13	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
14	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	basis	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	high	_	ADJ	_	Degree=Pos	_	_	_	_
12	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
13	weight	_	NOUN	_	Number=Sing	_	_	_	_
14	dextran	_	NOUN	_	Number=Sing	_	_	_	_
15	sulfate	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	HMDS	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
28	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
29	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
30	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
31	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
32	transferase	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	CAT	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	reporter	_	NOUN	_	Number=Sing	_	_	_	_
37	gene	_	NOUN	_	Number=Sing	_	_	_	_
38	under	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	control	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	HIV	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	long	_	ADJ	_	Degree=Pos	_	_	_	_
47	terminal	_	NOUN	_	Number=Sing	_	_	_	_
48	repeat	_	NOUN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	LTR	_	PROPN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	promoter	_	NOUN	_	Number=Sing	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	which	_	PRON	_	PronType=Rel	_	_	_	_
55	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
56	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
57	by	_	ADP	_	_	_	_	_	_
58	transcription	_	NOUN	_	Number=Sing	_	_	_	_
59	factor	_	NOUN	_	Number=Sing	_	_	_	_
60	NF	_	PROPN	_	Number=Sing	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	HMDS	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	similar	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
9	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	LPS	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	CAT	_	NOUN	_	Number=Sing	_	_	_	_
19	reporter	_	NOUN	_	Number=Sing	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	B7.1	_	NOUN	_	Number=Sing	_	_	_	_
14	molecules	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	postulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	might	_	AUX	_	VerbForm=Fin	_	_	_	_
13	play	_	VERB	_	VerbForm=Inf	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	accessory	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	as	_	ADV	_	_	_	_	_	_
24	well	_	ADV	_	Degree=Pos	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	rate	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	replication	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	HIV	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002237	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	ETS1	_	PROPN	_	Number=Sing	_	_	_	_
2	transactivates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	GM	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	CSF	_	NOUN	_	Number=Sing	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	PMA	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	ionomycin	_	PROPN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	helper	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	results	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	coordinate	_	ADJ	_	Degree=Pos	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	number	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
15	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	haematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
25	system	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
4	colony	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	GM	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	CSF	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	one	_	NUM	_	NumType=Card	_	_	_	_
15	such	_	ADJ	_	Degree=Pos	_	_	_	_
16	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
17	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
18	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	results	_	NOUN	_	Number=Plur	_	_	_	_
21	partly	_	ADV	_	_	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	increases	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Cis	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	acting	_	VERB	_	Number=Sing	_	_	_	_
4	elements	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	kappa	_	PROPN	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	ETS	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	like	_	ADP	_	Degree=Pos	_	_	_	_
17	motifs	_	NOUN	_	Number=Plur	_	_	_	_
18	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
20	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	promoter	_	ADJ	_	Number=Sing	_	_	_	_
24	region	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	GM	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	CSF	_	PROPN	_	Number=Sing	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	important	_	ADJ	_	Degree=Pos	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
37	activity	_	NOUN	_	Number=Sing	_	_	_	_
38	following	_	VERB	_	VerbForm=Ger	_	_	_	_
39	PMA	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	ionomycin	_	ADJ	_	Number=Sing	_	_	_	_
42	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	number	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	ETS	_	PROPN	_	Number=Sing	_	_	_	_
6	family	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factors	_	NOUN	_	Number=Plur	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	including	_	VERB	_	VerbForm=Ger	_	_	_	_
17	ETS1	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	ELF1	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	ability	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	GM5	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	within	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	CLE0	_	PROPN	_	Number=Sing	_	_	_	_
22	element	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	47	_	NUM	_	NumType=Card	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	-	_	SYM	_	_	_	_	_	_
28	40	_	NUM	_	NumType=Card	_	_	_	_
29	upstream	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	GM	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	CSF	_	PROPN	_	Number=Sing	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	initiation	_	NOUN	_	Number=Sing	_	_	_	_
37	site	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
2	ETS1	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	but	_	CCONJ	_	_	_	_	_	_
5	not	_	ADV	_	_	_	_	_	_
6	ELF1	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	GM	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	CSF	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	GM5	_	PROPN	_	Number=Sing	_	_	_	_
17	site	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	PMA	_	PROPN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
24	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
25	manner	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Other	_	ADJ	_	Degree=Pos	_	_	_	_
2	unidentified	_	ADJ	_	Degree=Pos	_	_	_	_
3	ETS	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	like	_	ADJ	_	Degree=Pos	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	present	_	VERB	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	capable	_	ADJ	_	Degree=Pos	_	_	_	_
14	of	_	SCONJ	_	_	_	_	_	_
15	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
16	GM5	_	PROPN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	core	_	NOUN	_	Number=Sing	_	_	_	_
5	ETS	_	NOUN	_	Number=Sing	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	GGAA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	GGAT	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	ETS	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	like	_	ADJ	_	Degree=Pos	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	exception	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	ETS1	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GM	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	CSF	_	NOUN	_	Number=Sing	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	way	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	ETS1	_	PROPN	_	Number=Sing	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	fully	_	ADV	_	_	_	_	_	_
18	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	PMA	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
23	induction	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	addition	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	ETS1	_	NOUN	_	Number=Sing	_	_	_	_
29	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	presence	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	PMA	_	PROPN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	ionomycin	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	data	_	NOUN	_	Number=Sing	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	ETS1	_	PROPN	_	Number=Sing	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	involved	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	SCONJ	_	_	_	_	_	_
11	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	GM	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	CSF	_	NOUN	_	Number=Sing	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002240	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
2	anti-endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	patient	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	Takayasu	_	PROPN	_	Number=Sing	_	_	_	_
10	arteritis	_	NOUN	_	Number=Sing	_	_	_	_
11	activate	_	VERB	_	Degree=Pos	_	_	_	_
12	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	large	_	ADJ	_	Degree=Pos	_	_	_	_
16	vessels	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	OBJECTIVE	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	create	_	VERB	_	VerbForm=Inf	_	_	_	_
3	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
4	anti-endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	mAECA	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	patient	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	Takayasu	_	PROPN	_	Number=Sing	_	_	_	_
15	arteritis	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	evaluate	_	VERB	_	VerbForm=Inf	_	_	_	_
18	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	ability	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
24	vein	_	NOUN	_	Number=Sing	_	_	_	_
25	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	HUVEC	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	EC	_	NOUN	_	Number=Sing	_	_	_	_
38	activation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	panel	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	mAECA	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	generated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
9	blood	_	NOUN	_	Number=Sing	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	patient	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	Takayasu	_	PROPN	_	Number=Sing	_	_	_	_
16	arteritis	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	using	_	VERB	_	VerbForm=Ger	_	_	_	_
19	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	Barr	_	PROPN	_	Number=Sing	_	_	_	_
22	virus	_	NOUN	_	Number=Sing	_	_	_	_
23	transformation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Activity	_	NOUN	_	Number=Sing	_	_	_	_
2	against	_	ADP	_	_	_	_	_	_
3	macrovascular	_	ADJ	_	Degree=Pos	_	_	_	_
4	EC	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	HUVEC	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	microvascular	_	ADJ	_	Degree=Pos	_	_	_	_
10	EC	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	bone	_	NOUN	_	Number=Sing	_	_	_	_
14	marrow	_	NOUN	_	Number=Sing	_	_	_	_
15	EC	_	PROPN	_	Number=Sing	_	_	_	_
16	immortalized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	SV40	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	antigens	_	NOUN	_	Number=Plur	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	immunosorbent	_	ADJ	_	Degree=Pos	_	_	_	_
28	assay	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	select	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
9	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	mAECA	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	share	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	same	_	ADJ	_	Degree=Pos	_	_	_	_
17	EC	_	NOUN	_	Number=Sing	_	_	_	_
18	epitope	_	NOUN	_	Number=Sing	_	_	_	_
19	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
20	specificity	_	NOUN	_	Number=Sing	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	total	_	ADJ	_	Degree=Pos	_	_	_	_
24	IgG	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	AECA	_	PROPN	_	Number=Sing	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	Takayasu	_	PROPN	_	Number=Sing	_	_	_	_
30	arteritis	_	NOUN	_	Number=Sing	_	_	_	_
31	patient	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	mAECA	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	aortic	_	ADJ	_	Degree=Pos	_	_	_	_
9	EC	_	PROPN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	immunohistochemistry	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	secretion	_	NOUN	_	Number=Sing	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	6	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	6	_	NUM	_	NumType=Card	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	von	_	NOUN	_	Number=Sing	_	_	_	_
15	Willebrand	_	PROPN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	vWF	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	determined	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	markers	_	NOUN	_	Number=Plur	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	EC	_	NOUN	_	Number=Sing	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	EC	_	PROPN	_	Number=Sing	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	adherence	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	line	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	U937	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	as	_	ADV	_	_	_	_	_	_
19	well	_	ADV	_	Degree=Pos	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
27	molecule	_	NOUN	_	Number=Sing	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
31	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
32	molecule	_	NOUN	_	Number=Sing	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	E-selectin	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	extracts	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	mAECA	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	EC	_	PROPN	_	Number=Sing	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	translocation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	using	_	VERB	_	VerbForm=Ger	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	specific	_	ADJ	_	Degree=Pos	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
35	oligoprobe	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
39	mobility	_	NOUN	_	Number=Sing	_	_	_	_
40	shift	_	NOUN	_	Number=Sing	_	_	_	_
41	assay	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Six	_	NUM	_	NumType=Card	_	_	_	_
4	mAECA	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	selected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	mixture	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	100	_	NUM	_	NumType=Card	_	_	_	_
14	%	_	SYM	_	Number=Sing	_	_	_	_
15	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	original	_	ADJ	_	Degree=Pos	_	_	_	_
21	IgG	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	patient	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	Takayasu	_	PROPN	_	Number=Sing	_	_	_	_
28	arteritis	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	HUVEC	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	mAECA	_	NOUN	_	_	_	_	_	_
3	possessed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	high	_	ADJ	_	Degree=Pos	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	against	_	ADP	_	_	_	_	_	_
7	macrovascular	_	ADJ	_	Degree=Pos	_	_	_	_
8	EC	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	none	_	NOUN	_	Number=Sing	_	_	_	_
12	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	significant	_	ADJ	_	Degree=Pos	_	_	_	_
14	antimicrovascular	_	ADJ	_	Degree=Pos	_	_	_	_
15	EC	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mAECA	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	but	_	CCONJ	_	_	_	_	_	_
5	not	_	ADV	_	_	_	_	_	_
6	normal	_	ADJ	_	Degree=Pos	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	IgG	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	anti-human	_	ADJ	_	Degree=Pos	_	_	_	_
12	aortic	_	ADJ	_	Degree=Pos	_	_	_	_
13	EC	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Four	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	6	_	NUM	_	NumType=Card	_	_	_	_
5	mAECA	_	PROPN	_	Number=Sing	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	EC	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	manifested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	6	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	vWF	_	NOUN	_	Number=Sing	_	_	_	_
17	secretion	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	4	_	NUM	_	NumType=Card	_	_	_	_
3	mAECA	_	NOUN	_	Number=Sing	_	_	_	_
4	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	EC	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
9	molecules	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	U937	_	NUM	_	Number=Sing	_	_	_	_
15	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	EC	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	mAECA	_	NOUN	_	Number=Plur	_	_	_	_
6	stimulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	translocation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSION	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	AECA	_	PROPN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	directly	_	ADV	_	_	_	_	_	_
8	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	EC	_	PROPN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	Takayasu	_	PROPN	_	Number=Sing	_	_	_	_
12	arteritis	_	NOUN	_	Number=Sing	_	_	_	_
13	through	_	ADP	_	_	_	_	_	_
14	elevation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
17	molecule	_	NOUN	_	Degree=Pos	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	may	_	AUX	_	VerbForm=Fin	_	_	_	_
32	therefore	_	ADV	_	_	_	_	_	_
33	play	_	VERB	_	VerbForm=Inf	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	pathogenic	_	ADJ	_	Degree=Pos	_	_	_	_
36	role	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	development	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	vasculopathy	_	NOUN	_	Number=Sing	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	Takayasu	_	PROPN	_	Number=Sing	_	_	_	_
45	arteritis	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002246	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Coexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	Rel	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	-T	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	syncytia	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Productive	_	ADJ	_	Degree=Pos	_	_	_	_
2	infection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
9	virus	_	NOUN	_	Number=Sing	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	_	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	typically	_	ADV	_	_	_	_	_	_
17	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	antigens	_	NOUN	_	Number=Plur	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	requirement	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	attributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	PROPN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	synergizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	drive	_	VERB	_	VerbForm=Inf	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	HIV	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	promoter	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	vigorous	_	ADJ	_	Degree=Pos	_	_	_	_
8	replication	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	takes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	place	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	nonactivated	_	ADJ	_	Degree=Pos	_	_	_	_
17	memory	_	NOUN	_	Number=Sing	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	after	_	ADP	_	_	_	_	_	_
21	syncytium	_	ADJ	_	Degree=Pos	_	_	_	_
22	formation	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	DCs	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	syncytia	_	NOUN	_	Degree=Pos	_	_	_	_
3	lack	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	as	_	SCONJ	_	_	_	_	_	_
7	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	absence	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	staining	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	Ki	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	67	_	NUM	_	NumType=Card	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	cycle	_	NOUN	_	Number=Sing	_	_	_	_
19	antigen	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	PROPN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	therefore	_	ADV	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	DCs	_	NOUN	_	Number=Sing	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	humans	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	mice	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	immunolabeling	_	ADJ	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	Western	_	ADJ	_	Degree=Pos	_	_	_	_
7	blot	_	NOUN	_	Number=Sing	_	_	_	_
8	analysis	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
12	mobility	_	NOUN	_	Number=Sing	_	_	_	_
13	shift	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	supershift	_	NOUN	_	Number=Sing	_	_	_	_
16	assays	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	lack	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	active	_	ADJ	_	Degree=Pos	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	express	_	VERB	_	Degree=Pos	_	_	_	_
11	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
12	as	_	SCONJ	_	_	_	_	_	_
13	expected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	DCs	_	PROPN	_	Number=Sing	_	_	_	_
2	express	_	VERB	_	Degree=Pos	_	_	_	_
3	high	_	ADJ	_	Degree=Pos	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	all	_	DET	_	_	_	_	_	_
7	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	Rel	_	NOUN	_	Number=Sing	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	residing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	primarily	_	ADV	_	_	_	_	_	_
20	within	_	ADP	_	_	_	_	_	_
21	RelB	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	p50	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	p65	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	DCs	_	PROPN	_	Number=Sing	_	_	_	_
4	lack	_	VERB	_	Number=Sing	_	_	_	_
5	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	failure	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	DCs	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Coexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
9	occurs	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
13	DC	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
16	syncytia	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	HIV	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	X	_	NumType=Card	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_
25	Therefore	_	ADV	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	HIV	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	fusion	_	NOUN	_	Number=Sing	_	_	_	_
34	brings	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	together	_	ADV	_	_	_	_	_	_
36	factors	_	NOUN	_	Number=Plur	_	_	_	_
37	that	_	PRON	_	PronType=Rel	_	_	_	_
38	upregulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	virus	_	NOUN	_	Number=Sing	_	_	_	_
40	transcription	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	DCs	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	memory	_	NOUN	_	Number=Sing	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	frequently	_	ADV	_	_	_	_	_	_
8	traffic	_	VERB	_	Number=Sing	_	_	_	_
9	together	_	ADV	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	situ	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	unusual	_	ADJ	_	Degree=Pos	_	_	_	_
15	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
16	syncytia	_	NOUN	_	Number=Sing	_	_	_	_
17	could	_	AUX	_	VerbForm=Fin	_	_	_	_
18	develop	_	VERB	_	VerbForm=Inf	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	infected	_	VERB	_	Degree=Pos	_	_	_	_
21	individuals	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	chronic	_	ADJ	_	VerbForm=Inf	_	_	_	_
26	HIV	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	replication	_	NOUN	_	Number=Sing	_	_	_	_
30	without	_	ADP	_	_	_	_	_	_
31	ostensible	_	ADJ	_	Degree=Pos	_	_	_	_
32	immune	_	ADJ	_	Degree=Pos	_	_	_	_
33	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002252	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Possible	_	ADJ	_	Degree=Pos	_	_	_	_
2	differences	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	s	_	X	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	action	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	different	_	ADJ	_	Degree=Pos	_	_	_	_
13	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
14	hormone	_	NOUN	_	Number=Sing	_	_	_	_
15	compounds	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Different	_	ADJ	_	Degree=Pos	_	_	_	_
2	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
3	hormones	_	NOUN	_	Number=Plur	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	GCH	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	show	_	VERB	_	Number=Sing	_	_	_	_
8	differences	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	intensity	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	immunomodulating	_	ADJ	_	Degree=Pos	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	s	_	X	_	_	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	action	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	GCH	_	PROPN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	under	_	ADP	_	_	_	_	_	_
12	investigation	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
18	noted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
21	exert	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	immune	_	ADJ	_	Degree=Pos	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	via	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
27	pathway	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	prednisone	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	PDN	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	deflazacort	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	DFC	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	DXM	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	production	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	6	_	NUM	_	NumType=Card	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	TNF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	alpha	_	PROPN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	10	_	NUM	_	NumType=Card	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	by	_	ADP	_	_	_	_	_	_
45	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
46	T	_	NOUN	_	Number=Sing	_	_	_	_
47	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	effects	_	NOUN	_	Number=Plur	_	_	_	_
52	on	_	ADP	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
55	of	_	ADP	_	_	_	_	_	_
56	NF	_	PROPN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	kB	_	NOUN	_	Number=Sing	_	_	_	_
59	DNA	_	NOUN	_	Number=Sing	_	_	_	_
60	binding	_	VERB	_	Number=Sing	_	_	_	_
61	activity	_	NOUN	_	Number=Sing	_	_	_	_
62	by	_	ADP	_	_	_	_	_	_
63	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
64	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
65	cell	_	NOUN	_	Number=Sing	_	_	_	_
66	line	_	NOUN	_	Number=Sing	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	obtained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	show	_	VERB	_	Number=Sing	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	three	_	NUM	_	NumType=Card	_	_	_	_
8	GCH	_	NOUN	_	Number=Sing	_	_	_	_
9	molecules	_	NOUN	_	Number=Plur	_	_	_	_
10	exert	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	immunosuppression	_	NOUN	_	Number=Sing	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
15	production	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	strong	_	ADJ	_	Degree=Pos	_	_	_	_
22	decrease	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	translocation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kB	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	;	_	PUNCT	_	_	_	_	_	_
35	moreover	_	ADV	_	_	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	a	_	X	_	_	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	not	_	ADV	_	_	_	_	_	_
41	all	_	DET	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
44	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
46	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	not	_	ADV	_	_	_	_	_	_
50	with	_	ADP	_	_	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	same	_	ADJ	_	Degree=Pos	_	_	_	_
53	intensity	_	NOUN	_	Number=Sing	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	by	_	ADP	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	three	_	NUM	_	NumType=Card	_	_	_	_
58	GCH	_	NOUN	_	Number=Sing	_	_	_	_
59	and	_	CCONJ	_	_	_	_	_	_
60	(	_	PUNCT	_	_	_	_	_	_
61	b	_	X	_	_	_	_	_	_
62	)	_	PUNCT	_	_	_	_	_	_
63	DXM	_	PROPN	_	Number=Sing	_	_	_	_
64	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
65	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
66	binding	_	NOUN	_	Number=Sing	_	_	_	_
67	activity	_	NOUN	_	Number=Sing	_	_	_	_
68	of	_	ADP	_	_	_	_	_	_
69	NF	_	PROPN	_	Number=Sing	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	kB	_	NOUN	_	Number=Sing	_	_	_	_
72	less	_	ADJ	_	Degree=Cmp	_	_	_	_
73	than	_	ADP	_	_	_	_	_	_
74	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
75	of	_	ADP	_	_	_	_	_	_
76	DFC	_	NOUN	_	Number=Sing	_	_	_	_
77	and	_	CCONJ	_	_	_	_	_	_
78	PDN	_	NOUN	_	Number=Sing	_	_	_	_
79	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	agreement	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	concept	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	different	_	ADJ	_	Degree=Pos	_	_	_	_
11	GCH	_	NOUN	_	Number=Sing	_	_	_	_
12	compounds	_	NOUN	_	Number=Plur	_	_	_	_
13	might	_	AUX	_	VerbForm=Fin	_	_	_	_
14	differ	_	VERB	_	VerbForm=Inf	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	affinity	_	NOUN	_	Number=Sing	_	_	_	_
20	properties	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	tissue	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	metabolism	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	interaction	_	NOUN	_	Number=Sing	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002253	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	patients	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	systemic	_	ADJ	_	Degree=Pos	_	_	_	_
14	lupus	_	NOUN	_	Number=Sing	_	_	_	_
15	erythematosus	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	p65	_	NUM	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	RelA	_	NOUN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Numerous	_	ADJ	_	Degree=Pos	_	_	_	_
2	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
5	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	immune	_	ADJ	_	Degree=Pos	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	patients	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	systemic	_	ADJ	_	Degree=Pos	_	_	_	_
16	lupus	_	NOUN	_	Number=Sing	_	_	_	_
17	erythematosus	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	SLE	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	including	_	VERB	_	VerbForm=Ger	_	_	_	_
23	surface	_	NOUN	_	Number=Sing	_	_	_	_

1	Ag	_	NOUN	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	signaling	_	VERB	_	Number=Sing	_	_	_	_
6	events	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	PROPN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	numerous	_	ADJ	_	Degree=Pos	_	_	_	_
12	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
22	target	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	antiinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	drugs	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
28	sought	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	functional	_	ADJ	_	Degree=Pos	_	_	_	_
33	role	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappa	_	NOUN	_	Number=Sing	_	_	_	_
39	B	_	NOUN	_	Number=Sing	_	_	_	_
40	protein	_	NOUN	_	Number=Sing	_	_	_	_
41	complex	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	lupus	_	NOUN	_	Number=Sing	_	_	_	_
44	T	_	PROPN	_	Number=Sing	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Freshly	_	ADV	_	_	_	_	_	_
2	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	lupus	_	NOUN	_	Number=Sing	_	_	_	_
7	patients	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	rheumatoid	_	VERB	_	Number=Sing	_	_	_	_
10	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	RA	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	patients	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	normal	_	ADJ	_	Degree=Pos	_	_	_	_
18	individuals	_	NOUN	_	Number=Plur	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	physiologically	_	ADV	_	_	_	_	_	_
22	via	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	TCR	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	anti-CD3	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	anti-CD28	_	ADJ	_	Degree=Pos	_	_	_	_
29	Abs	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	assess	_	VERB	_	VerbForm=Inf	_	_	_	_
32	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
33	membrane	_	NOUN	_	Number=Sing	_	_	_	_
34	signaling	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	PMA	_	PROPN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	calcium	_	NOUN	_	Number=Sing	_	_	_	_
42	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	A23187	_	NOUN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	to	_	PART	_	_	_	_	_	_
47	bypass	_	VERB	_	VerbForm=Inf	_	_	_	_
48	membrane	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	signaling	_	NOUN	_	Number=Sing	_	_	_	_
52	events	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	measured	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	extracts	_	NOUN	_	Number=Plur	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	gel	_	NOUN	_	Number=Sing	_	_	_	_
15	shift	_	NOUN	_	Number=Sing	_	_	_	_
16	analysis	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	normal	_	ADJ	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	SLE	_	PROPN	_	Number=Sing	_	_	_	_
17	patients	_	NOUN	_	Number=Plur	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	significantly	_	ADV	_	_	_	_	_	_
20	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	SLE	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	not	_	ADV	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	RA	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	patients	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	absent	_	VERB	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	several	_	ADJ	_	Degree=Pos	_	_	_	_
11	SLE	_	ADJ	_	Number=Sing	_	_	_	_
12	patients	_	NOUN	_	Number=Plur	_	_	_	_
13	who	_	PRON	_	PronType=Rel	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	receiving	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
17	any	_	DET	_	_	_	_	_	_
18	medication	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	including	_	VERB	_	VerbForm=Ger	_	_	_	_
21	corticosteroids	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Also	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	absent	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	follow	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	up	_	NOUN	_	Number=Sing	_	_	_	_
14	studies	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	supershift	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	using	_	VERB	_	VerbForm=Ger	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	Abs	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	group	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	SLE	_	ADJ	_	Number=Sing	_	_	_	_
17	patients	_	NOUN	_	Number=Plur	_	_	_	_
18	who	_	PRON	_	PronType=Rel	_	_	_	_
19	displayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	undetectable	_	ADJ	_	Degree=Pos	_	_	_	_
21	NF	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	p65	_	NOUN	_	Number=Sing	_	_	_	_
28	complexes	_	NOUN	_	Number=Plur	_	_	_	_
29	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	not	_	PART	_	_	_	_	_	_
31	formed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	immunoblot	_	ADJ	_	Degree=Pos	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	extracts	_	NOUN	_	Number=Plur	_	_	_	_
8	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	absent	_	ADJ	_	Degree=Pos	_	_	_	_
12	p65	_	NUM	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	p65	_	NOUN	_	Number=Sing	_	_	_	_
3	complexes	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	transcriptionally	_	ADV	_	_	_	_	_	_
6	active	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	comparison	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	p50	_	PROPN	_	Number=Sing	_	_	_	_
12	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
15	novel	_	NOUN	_	Number=Sing	_	_	_	_
16	finding	_	NOUN	_	Number=Sing	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
19	insight	_	NOUN	_	Number=Sing	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	origin	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
25	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	other	_	ADJ	_	Degree=Pos	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	SLE	_	PROPN	_	Number=Sing	_	_	_	_
32	patients	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002268	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Fas	_	NOUN	_	Number=Sing	_	_	_	_
18	ligand	_	NOUN	_	Number=Sing	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Apoptosis	_	PROPN	_	Number=Sing	_	_	_	_
2	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	through	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	TCR	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	CD4	_	PROPN	_	Number=Sing	_	_	_	_
8	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	mostly	_	ADV	_	_	_	_	_	_
5	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Fas	_	PROPN	_	Number=Sing	_	_	_	_
12	ligand	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	FasL	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	primary	_	ADJ	_	Degree=Pos	_	_	_	_
19	event	_	NOUN	_	Number=Sing	_	_	_	_
20	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	commitment	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	death	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	gain	_	VERB	_	VerbForm=Inf	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	better	_	ADJ	_	Degree=Cmp	_	_	_	_
5	understanding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	events	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	took	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	advantage	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
20	previously	_	ADV	_	_	_	_	_	_
21	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	mutant	_	ADJ	_	Number=Sing	_	_	_	_
23	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	FasL	_	ADJ	_	Degree=Pos	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	upon	_	ADP	_	_	_	_	_	_
12	TCR	_	NOUN	_	Number=Sing	_	_	_	_
13	triggering	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	although	_	SCONJ	_	_	_	_	_	_
16	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	IFN	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	gamma	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	production	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	normal	_	ADJ	_	Degree=Pos	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	both	_	CCONJ	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	FasL	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	consensus	_	NOUN	_	Number=Sing	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	reporter	_	NOUN	_	Number=Sing	_	_	_	_
17	construct	_	NOUN	_	Number=Sing	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	inefficiently	_	ADV	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	wild	_	ADJ	_	Degree=Pos	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	type	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	FasL	_	ADJ	_	Number=Sing	_	_	_	_
14	reporter	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	could	_	AUX	_	VerbForm=Fin	_	_	_	_
5	trace	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	deficit	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	inefficient	_	ADJ	_	Degree=Pos	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	evidencing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
23	role	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	regulation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	FasL	_	ADJ	_	Degree=Pos	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	T	_	NOUN	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	induction	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	FasL	_	ADJ	_	Number=Sing	_	_	_	_
11	versus	_	ADP	_	_	_	_	_	_
12	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	differentially	_	ADV	_	_	_	_	_	_
17	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	deprivation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002274	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	proenkephalin	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	JunD	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	JunB	_	PROPN	_	Number=Sing	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	positive	_	ADJ	_	Degree=Pos	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	negative	_	ADJ	_	Degree=Pos	_	_	_	_
15	effects	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	AP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	proteins	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	JunD	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	component	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	complex	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	proenkephalin	_	NOUN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	fashion	_	NOUN	_	Number=Sing	_	_	_	_
27	that	_	PRON	_	PronType=Rel	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	completely	_	ADV	_	_	_	_	_	_
30	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
31	upon	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
36	protein	_	NOUN	_	Number=Sing	_	_	_	_
37	kinase	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	protein	_	NOUN	_	Number=Sing	_	_	_	_
40	kinase	_	NOUN	_	Number=Sing	_	_	_	_
41	A.	_	PROPN	_	Number=Sing	_	_	_	_
42	Activation	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	proenkephalin	_	ADJ	_	Number=Sing	_	_	_	_
45	transcription	_	NOUN	_	Number=Sing	_	_	_	_
46	by	_	ADP	_	_	_	_	_	_
47	JunD	_	PROPN	_	Number=Sing	_	_	_	_
48	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
50	upon	_	ADP	_	_	_	_	_	_
51	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
52	previously	_	ADV	_	_	_	_	_	_
53	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
54	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
58	ester	_	NOUN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	,	_	PUNCT	_	_	_	_	_	_
61	and	_	CCONJ	_	_	_	_	_	_
62	Ca	_	PROPN	_	Number=Sing	_	_	_	_
63	(	_	PUNCT	_	_	_	_	_	_
64	2	_	NUM	_	NumType=Card	_	_	_	_
65	+	_	SYM	_	_	_	_	_	_
66	)	_	PUNCT	_	_	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
69	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
70	,	_	PUNCT	_	_	_	_	_	_
71	and	_	CCONJ	_	_	_	_	_	_
72	JunD	_	PROPN	_	Number=Sing	_	_	_	_
73	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
74	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
75	to	_	PART	_	_	_	_	_	_
76	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
77	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
78	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
79	as	_	ADP	_	_	_	_	_	_
80	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
81	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
82	.	_	PUNCT	_	_	_	_	_	_

1	Another	_	DET	_	_	_	_	_	_
2	component	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	AP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	complex	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	JunB	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	JunD	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
4	JunB	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	unable	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
11	;	_	PUNCT	_	_	_	_	_	_
12	however	_	ADV	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	presence	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	high	_	ADJ	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	affinity	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	JunD	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
17	ester	_	NOUN	_	Number=Sing	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	elements	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	A	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	fashion	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	further	_	ADV	_	_	_	_	_	_
30	blurring	_	VERB	_	VerbForm=Ger	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	distinction	_	NOUN	_	Number=Sing	_	_	_	_
33	between	_	ADP	_	_	_	_	_	_
34	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
35	response	_	NOUN	_	Number=Sing	_	_	_	_
36	elements	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	related	_	ADJ	_	Degree=Pos	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	second	_	ADJ	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	messenger	_	NOUN	_	Number=Sing	_	_	_	_
26	pathway	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	JunD	_	PROPN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	other	_	ADJ	_	Degree=Pos	_	_	_	_
33	AP	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	related	_	ADJ	_	Degree=Pos	_	_	_	_
38	proteins	_	NOUN	_	Number=Plur	_	_	_	_
39	may	_	AUX	_	VerbForm=Fin	_	_	_	_
40	play	_	VERB	_	VerbForm=Inf	_	_	_	_
41	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	important	_	ADJ	_	Degree=Pos	_	_	_	_
43	role	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	regulation	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	gene	_	NOUN	_	Number=Sing	_	_	_	_
49	expression	_	NOUN	_	Number=Sing	_	_	_	_
50	by	_	ADP	_	_	_	_	_	_
51	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
54	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
55	signaling	_	NOUN	_	Number=Sing	_	_	_	_
56	pathways	_	NOUN	_	Number=Plur	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002277	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Triggering	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	6	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	interferon	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	gamma	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	tumor	_	NOUN	_	Number=Sing	_	_	_	_
15	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
24	between	_	ADP	_	_	_	_	_	_
25	interferon	_	NOUN	_	Number=Sing	_	_	_	_
26	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	factors	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	basis	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	interferon	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	IFN	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	gamma	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	tumor	_	NOUN	_	Number=Sing	_	_	_	_
21	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	TNF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	6	_	NUM	_	NumType=Card	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	6	_	NUM	_	NumType=Card	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	THP	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
50	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
51	with	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	basis	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
56	induction	_	NOUN	_	Number=Sing	_	_	_	_
57	by	_	ADP	_	_	_	_	_	_
58	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
59	(	_	PUNCT	_	_	_	_	_	_
60	LPS	_	NOUN	_	Number=Sing	_	_	_	_
61	)	_	PUNCT	_	_	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	three	_	NUM	_	NumType=Card	_	_	_	_
11	regions	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	targets	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	IFN	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	gamma	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	TNF	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	action	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	whereas	_	SCONJ	_	_	_	_	_	_
29	only	_	ADV	_	_	_	_	_	_
30	one	_	NUM	_	NumType=Card	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
33	regions	_	NOUN	_	Number=Plur	_	_	_	_
34	seemed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	be	_	AUX	_	VerbForm=Inf	_	_	_	_
37	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	LPS	_	NOUN	_	Number=Sing	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	three	_	NUM	_	NumType=Card	_	_	_	_
3	regions	_	NOUN	_	Number=Plur	_	_	_	_
4	concerned	_	ADJ	_	Degree=Pos	_	_	_	_
5	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	:	_	PUNCT	_	_	_	_	_	_

1	1	_	X	_	_	_	_	_	_
2	)	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	between	_	ADP	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	73	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	-	_	SYM	_	_	_	_	_	_
10	36	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	inducible	_	ADJ	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	LPS	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	TNF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	;	_	PUNCT	_	_	_	_	_	_
25	2	_	X	_	_	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	element	_	NOUN	_	Number=Sing	_	_	_	_
29	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	between	_	ADP	_	_	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	181	_	NUM	_	NumType=Card	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	-	_	SYM	_	_	_	_	_	_
35	73	_	NUM	_	NumType=Card	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	which	_	PRON	_	PronType=Rel	_	_	_	_
38	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
39	to	_	PART	_	_	_	_	_	_
40	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	response	_	NOUN	_	Number=Sing	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	IFN	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	gamma	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	TNF	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	alpha	_	NOUN	_	Number=Sing	_	_	_	_
51	negatively	_	ADV	_	_	_	_	_	_
52	;	_	PUNCT	_	_	_	_	_	_
53	and	_	CCONJ	_	_	_	_	_	_
54	3	_	X	_	_	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
57	distal	_	ADJ	_	Degree=Pos	_	_	_	_
58	element	_	NOUN	_	Number=Sing	_	_	_	_
59	upstream	_	NOUN	_	Number=Sing	_	_	_	_
60	of	_	ADP	_	_	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	224	_	NUM	_	NumType=Card	_	_	_	_
63	,	_	PUNCT	_	_	_	_	_	_
64	which	_	PRON	_	PronType=Rel	_	_	_	_
65	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
66	inducible	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
67	by	_	ADP	_	_	_	_	_	_
68	IFN	_	PROPN	_	Number=Sing	_	_	_	_
69	-	_	PUNCT	_	_	_	_	_	_
70	gamma	_	NOUN	_	Number=Sing	_	_	_	_
71	alone	_	ADJ	_	_	_	_	_	_
72	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	PROPN	_	Number=Sing	_	_	_	_
2	signaling	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
14	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	6	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	IFN	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	gamma	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	involved	_	VERB	_	Degree=Pos	_	_	_	_
23	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
24	between	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	IRF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	PROPN	_	Number=Sing	_	_	_	_
33	p65	_	NOUN	_	Number=Sing	_	_	_	_
34	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
37	removal	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	negative	_	ADJ	_	Degree=Pos	_	_	_	_
41	effect	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	retinoblastoma	_	PROPN	_	Number=Sing	_	_	_	_
45	control	_	NOUN	_	Number=Sing	_	_	_	_
46	element	_	NOUN	_	Number=Sing	_	_	_	_
47	present	_	VERB	_	Number=Sing	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	IL	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	6	_	NUM	_	NumType=Card	_	_	_	_
53	promoter	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	removal	_	NOUN	_	Number=Sing	_	_	_	_
3	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
9	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
13	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	IFN	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	gamma	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002279	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Preassociation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	STAT2	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	separate	_	ADJ	_	Degree=Pos	_	_	_	_
10	signalling	_	NOUN	_	Number=Sing	_	_	_	_
11	complexes	_	NOUN	_	Number=Plur	_	_	_	_
12	prior	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	cytokine	_	VERB	_	Number=Sing	_	_	_	_
15	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	variety	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	growth	_	NOUN	_	Number=Sing	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	act	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	family	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	latent	_	ADJ	_	Degree=Pos	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	STAT	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	signal	_	NOUN	_	Number=Sing	_	_	_	_
27	transducers	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	activators	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	proteins	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Ligand	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	STATs	_	NOUN	_	Number=Plur	_	_	_	_
9	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
14	formation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	translocation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	STAT	_	PROPN	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	heterocomplexes	_	NOUN	_	Number=Plur	_	_	_	_
8	exist	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	prior	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	cytokine	_	VERB	_	Number=Sing	_	_	_	_
12	treatment	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
3	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	ruptured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	hypotonic	_	ADJ	_	Degree=Pos	_	_	_	_
9	buffer	_	NOUN	_	Number=Sing	_	_	_	_
10	without	_	ADP	_	_	_	_	_	_
11	salt	_	NOUN	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	detergent	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	immunoadsorption	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	either	_	CCONJ	_	_	_	_	_	_
18	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	STAT2	_	NOUN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
25	yields	_	NOUN	_	Number=Plur	_	_	_	_
26	coimmunoadsorption	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	other	_	ADJ	_	Degree=Pos	_	_	_	_
30	STAT	_	NOUN	_	Number=Sing	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Similarly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
6	heterocomplexes	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	coimmunoadsorbed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	hypotonic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	STAT2	_	PROPN	_	Number=Sing	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
8	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	reticulocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	lysate	_	NOUN	_	Number=Sing	_	_	_	_
12	spontaneously	_	ADV	_	_	_	_	_	_
13	form	_	VERB	_	VerbForm=Inf	_	_	_	_
14	heterocomplexes	_	NOUN	_	Number=Plur	_	_	_	_
15	when	_	ADV	_	PronType=Int	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	translation	_	NOUN	_	Number=Sing	_	_	_	_
18	lysates	_	NOUN	_	Number=Plur	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	mixed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	0	_	NUM	_	NumType=Card	_	_	_	_
23	degrees	_	NOUN	_	Number=Plur	_	_	_	_
24	C.	_	PROPN	_	Number=Sing	_	_	_	_
25	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
26	data	_	NOUN	_	Number=Sing	_	_	_	_
27	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	interferon	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	beta	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
37	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
38	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	stability	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	preexisting	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	latent	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	STAT2	_	NOUN	_	Number=Sing	_	_	_	_
50	signaling	_	NOUN	_	Number=Sing	_	_	_	_
51	complex	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Newly	_	ADV	_	_	_	_	_	_
2	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
4	binds	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	equilibrium	_	NOUN	_	Degree=Pos	_	_	_	_
7	fashion	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	STAT2	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	STAT2	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
20	exist	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	separate	_	ADJ	_	Degree=Pos	_	_	_	_
23	heterocomplexes	_	NOUN	_	Number=Plur	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	model	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
34	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	common	_	ADJ	_	Degree=Pos	_	_	_	_
37	binding	_	NOUN	_	Number=Sing	_	_	_	_
38	site	_	NOUN	_	Number=Sing	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	other	_	ADJ	_	Degree=Pos	_	_	_	_
41	STAT	_	NOUN	_	Number=Sing	_	_	_	_
42	proteins	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002284	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	involvement	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
5	tumor	_	NOUN	_	Number=Sing	_	_	_	_
6	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	TNFR	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	signaling	_	VERB	_	Number=Sing	_	_	_	_
18	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	activator	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	member	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	TNFR	_	PROPN	_	Number=Sing	_	_	_	_
32	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Receptor	_	NOUN	_	Number=Sing	_	_	_	_
2	activator	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	RANK	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	recently	_	ADV	_	_	_	_	_	_
13	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	member	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	tumor	_	NOUN	_	Number=Sing	_	_	_	_
18	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	cognate	_	ADJ	_	Number=Sing	_	_	_	_
3	ligand	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	RANKL	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	significant	_	ADJ	_	Degree=Pos	_	_	_	_
9	roles	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	function	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	osteoclast	_	NOUN	_	Number=Sing	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	interaction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	RANK	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	TRAFs	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	3	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	5	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	6	_	NUM	_	NumType=Card	_	_	_	_
29	both	_	CCONJ	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	vitro	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Mapping	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	structural	_	ADJ	_	Degree=Pos	_	_	_	_
5	requirements	_	NOUN	_	Number=Plur	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	TRAF	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	RANK	_	NOUN	_	Number=Sing	_	_	_	_
10	interaction	_	NOUN	_	Number=Sing	_	_	_	_
11	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
13	TRAF	_	NOUN	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	sites	_	NOUN	_	Number=Plur	_	_	_	_
16	clustered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	two	_	NUM	_	NumType=Card	_	_	_	_
19	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
20	domains	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	RANK	_	PROPN	_	Number=Sing	_	_	_	_
24	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
25	tail	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	TRAF	_	NOUN	_	Number=Sing	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	domains	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	functionally	_	ADV	_	_	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	RANK	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
23	NH2	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
26	kinase	_	NOUN	_	Number=Sing	_	_	_	_
27	activities	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Site	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	TRAF	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	NOUN	_	VerbForm=Ger	_	_	_	_
10	sites	_	NOUN	_	Number=Plur	_	_	_	_
11	exhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	selective	_	ADJ	_	Degree=Pos	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	different	_	ADJ	_	Degree=Pos	_	_	_	_
16	TRAF	_	NOUN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	particular	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	TRAF6	_	PROPN	_	Number=Sing	_	_	_	_
5	interacted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	membrane	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
10	determinants	_	NOUN	_	Number=Plur	_	_	_	_
11	distinct	_	VERB	_	Degree=Pos	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	TRAFs	_	NOUN	_	Number=Plur	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	5	_	NUM	_	NumType=Card	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	membrane	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
6	TRAF6	_	PROPN	_	Number=Sing	_	_	_	_
7	interaction	_	NOUN	_	Number=Sing	_	_	_	_
8	domain	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	deleted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	RANK	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	signaling	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	completely	_	ADV	_	_	_	_	_	_
21	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	while	_	SCONJ	_	_	_	_	_	_
23	c-Jun	_	PROPN	_	Number=Sing	_	_	_	_
24	NH2	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
27	kinase	_	NOUN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	partially	_	ADV	_	_	_	_	_	_
31	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	NH2-terminal	_	ADJ	_	Degree=Pos	_	_	_	_
3	truncation	_	NOUN	_	Number=Sing	_	_	_	_
4	mutant	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	TRAF6	_	PROPN	_	Number=Sing	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	RANKL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
20	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
21	signaling	_	NOUN	_	Number=Sing	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	revealing	_	VERB	_	VerbForm=Ger	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	selective	_	ADJ	_	Degree=Pos	_	_	_	_
30	role	_	NOUN	_	Number=Sing	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	TRAF6	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	ligand	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	events	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002287	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	AP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	150	_	NUM	_	NumType=Card	_	_	_	_
9	bp	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	ADV	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	likely	_	ADJ	_	Degree=Pos	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	major	_	ADJ	_	Degree=Pos	_	_	_	_
26	target	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	kinase	_	NOUN	_	Number=Sing	_	_	_	_
30	C	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
7	results	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	several	_	ADJ	_	Degree=Pos	_	_	_	_
12	kinases	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	including	_	VERB	_	VerbForm=Ger	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	kinase	_	NOUN	_	Number=Sing	_	_	_	_
17	C	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	PKC	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
23	may	_	AUX	_	VerbForm=Fin	_	_	_	_
24	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	later	_	ADJ	_	Degree=Cmp	_	_	_	_
27	induction	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	related	_	ADJ	_	Degree=Pos	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	potential	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	PKC	_	PROPN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	_	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	through	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	CD3	_	PROPN	_	Number=Sing	_	_	_	_
32	complex	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	DET	_	_	_	_	_	_
6	prolonged	_	VERB	_	Degree=Pos	_	_	_	_
7	treatment	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	untransformed	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	clone	_	NOUN	_	Number=Sing	_	_	_	_
14	Ar	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	SYM	_	_	_	_	_	_
16	5	_	NUM	_	NumType=Card	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
19	esters	_	NOUN	_	Number=Plur	_	_	_	_
20	results	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	downmodulation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	beta	_	NOUN	_	Number=Sing	_	_	_	_
28	isozymes	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	PKC	_	PROPN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	abrogates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	induction	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	protein	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
6	ester	_	NOUN	_	Number=Sing	_	_	_	_
7	treatment	_	NOUN	_	Number=Sing	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	abolishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
13	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	Ar	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	5	_	NUM	_	NumType=Card	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
24	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	reporter	_	NOUN	_	Number=Sing	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
8	sites	_	NOUN	_	Number=Plur	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	including	_	VERB	_	VerbForm=Ger	_	_	_	_
13	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	Oct	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	PROPN	_	Number=Sing	_	_	_	_
22	B	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	AP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	all	_	ADV	_	_	_	_	_	_
32	potentially	_	ADV	_	_	_	_	_	_
33	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	activation	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	PKC	_	PROPN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	trimer	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Oct	_	PROPN	_	Number=Sing	_	_	_	_
13	sites	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
19	ester	_	NOUN	_	Number=Sing	_	_	_	_
20	treatment	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
24	mutations	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	no	_	DET	_	_	_	_	_	_
34	effect	_	NOUN	_	Number=Sing	_	_	_	_
35	on	_	ADP	_	_	_	_	_	_
36	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	mutations	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	AP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	150	_	NUM	_	NumType=Card	_	_	_	_
15	bp	_	PROPN	_	Number=Sing	_	_	_	_
16	almost	_	ADV	_	_	_	_	_	_
17	completely	_	ADV	_	_	_	_	_	_
18	abrogate	_	ADJ	_	Degree=Pos	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	appearance	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
32	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	binding	_	VERB	_	Number=Sing	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
37	site	_	NOUN	_	Number=Sing	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	PKC	_	PROPN	_	Number=Sing	_	_	_	_
42	depletion	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cotransfections	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	c-jun	_	NOUN	_	Degree=Pos	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
10	markedly	_	ADV	_	_	_	_	_	_
11	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	minimally	_	ADV	_	_	_	_	_	_
21	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	AP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	150	_	NUM	_	NumType=Card	_	_	_	_
13	bp	_	PROPN	_	Number=Sing	_	_	_	_
14	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	major	_	ADJ	_	Degree=Pos	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	if	_	SCONJ	_	_	_	_	_	_
19	not	_	ADV	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	only	_	ADJ	_	Degree=Pos	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	PKC	_	PROPN	_	Number=Sing	_	_	_	_
26	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	promoter	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002289	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Lipopolysaccharide	_	ADJ	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	tumor	_	NOUN	_	Number=Sing	_	_	_	_
6	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	Egr	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Biosynthesis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	tumor	_	NOUN	_	Number=Sing	_	_	_	_
4	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	TNF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	predominantly	_	ADV	_	_	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
20	lineage	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	various	_	ADJ	_	Degree=Pos	_	_	_	_
8	cis	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	elements	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	LPS	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	TNF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
31	lineage	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
5	THP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
12	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	various	_	ADJ	_	Degree=Pos	_	_	_	_
14	lengths	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	localized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	elements	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	region	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	-	_	SYM	_	_	_	_	_	_
28	182	_	NUM	_	NumType=Card	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	-	_	SYM	_	_	_	_	_	_
31	37	_	NUM	_	NumType=Card	_	_	_	_
32	base	_	NOUN	_	Number=Sing	_	_	_	_
33	pairs	_	NOUN	_	Number=Plur	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	bp	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	that	_	PRON	_	PronType=Rel	_	_	_	_
39	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
43	transcription	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	TNF	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	alpha	_	NOUN	_	Number=Sing	_	_	_	_
49	gene	_	NOUN	_	Number=Sing	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	response	_	NOUN	_	Number=Sing	_	_	_	_
52	to	_	ADP	_	_	_	_	_	_
53	LPS	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	regions	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	:	_	PUNCT	_	_	_	_	_	_
6	region	_	NOUN	_	Number=Sing	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	(-	_	PUNCT	_	_	_	_	_	_
9	182	_	NUM	_	NumType=Card	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	162	_	NUM	_	NumType=Card	_	_	_	_
13	bp	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	overlapping	_	ADJ	_	Degree=Pos	_	_	_	_
18	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	Egr	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	region	_	NOUN	_	Number=Sing	_	_	_	_
27	II	_	NUM	_	NumType=Card	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	-	_	SYM	_	_	_	_	_	_
30	119	_	NUM	_	NumType=Card	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	-	_	SYM	_	_	_	_	_	_
33	88	_	NUM	_	NumType=Card	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	CRE	_	PROPN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	kappaB3	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	sites	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
3	THP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	CRE	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	lesser	_	ADJ	_	Degree=Cmp	_	_	_	_
16	extent	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	c	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	Jun	_	PROPN	_	Number=Sing	_	_	_	_
21	complexes	_	NOUN	_	Number=Plur	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	CRE	_	NOUN	_	Number=Sing	_	_	_	_
29	site	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	NOUN	_	Number=Sing	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	complexes	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	LPS	_	PROPN	_	Number=Sing	_	_	_	_
5	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	cognate	_	VERB	_	VerbForm=Ger	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	Egr	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	kappaB3	_	NOUN	_	Number=Sing	_	_	_	_
20	sites	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	Egr	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	respectively	_	ADV	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CRE	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	kappaB3	_	NOUN	_	Number=Sing	_	_	_	_
5	sites	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	II	_	PROPN	_	NumType=Card	_	_	_	_
9	together	_	ADV	_	_	_	_	_	_
10	conferred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	strong	_	ADJ	_	Degree=Pos	_	_	_	_
12	LPS	_	NOUN	_	Number=Sing	_	_	_	_
13	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	whereas	_	SCONJ	_	_	_	_	_	_
20	individually	_	ADV	_	_	_	_	_	_
21	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
22	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
25	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	spacing	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	CRE	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	kappaB3	_	NOUN	_	Number=Sing	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	completely	_	ADV	_	_	_	_	_	_
14	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	LPS	_	NOUN	_	Number=Sing	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	cooperative	_	ADJ	_	Degree=Pos	_	_	_	_
21	interaction	_	NOUN	_	Number=Sing	_	_	_	_
22	between	_	ADP	_	_	_	_	_	_
23	c	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	Jun	_	PROPN	_	Number=Sing	_	_	_	_
26	complexes	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	p50/p65	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
6	LPS	_	NOUN	_	Number=Sing	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	TNF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	concerted	_	ADJ	_	Degree=Pos	_	_	_	_
18	participation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	at	_	ADV	_	_	_	_	_	_
21	least	_	ADV	_	Degree=Sup	_	_	_	_
22	two	_	NUM	_	NumType=Card	_	_	_	_
23	separate	_	ADJ	_	Degree=Pos	_	_	_	_
24	cis	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
27	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	elements	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002291	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Synergism	_	NOUN	_	Number=Sing	_	_	_	_
2	between	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CD3	_	PROPN	_	Number=Sing	_	_	_	_
5	antigen	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	CD2	_	PROPN	_	Number=Sing	_	_	_	_
9	antigen	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	signals	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Exploration	_	NOUN	_	Number=Sing	_	_	_	_
2	at	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	level	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	DNA	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	characterization	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	cyclosporine	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	earlier	_	ADV	_	Degree=Cmp	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	crosslinkage	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	CD3	_	PROPN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	TCR	_	NOUN	_	Number=Sing	_	_	_	_
13	complex	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	CD2	_	NOUN	_	Number=Sing	_	_	_	_
17	antigen	_	NOUN	_	Number=Sing	_	_	_	_
18	results	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	normal	_	ADJ	_	Degree=Pos	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	synergism	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	perceptible	_	ADJ	_	Degree=Pos	_	_	_	_
8	at	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	level	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	process	_	NOUN	_	Number=Sing	_	_	_	_
22	critical	_	ADJ	_	Degree=Pos	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	T	_	PROPN	_	NumType=Card	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	growth	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	basis	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	synergism	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	explored	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	DNA	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	binding	_	VERB	_	Number=Sing	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	highly	_	ADV	_	_	_	_	_	_
25	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	normal	_	ADJ	_	Degree=Pos	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	signaled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	via	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	CD3	_	PROPN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	/	_	PUNCT	_	_	_	_	_	_
36	or	_	CCONJ	_	_	_	_	_	_
37	CD2	_	PROPN	_	Number=Sing	_	_	_	_
38	proteins	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transmembrane	_	ADJ	_	Number=Sing	_	_	_	_
5	signaling	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	sn	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	dioctanoyl	_	NOUN	_	Number=Sing	_	_	_	_
21	glycerol	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	also	_	ADV	_	_	_	_	_	_
25	determined	_	ADJ	_	Degree=Pos	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	emergence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	proteins	_	NOUN	_	Number=Plur	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	using	_	VERB	_	VerbForm=Ger	_	_	_	_
10	interleukin	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	sequence	_	NOUN	_	Number=Sing	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	oligonucleotide	_	ADJ	_	Number=Sing	_	_	_	_
16	probes	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
20	mobility	_	NOUN	_	Number=Sing	_	_	_	_
21	shift	_	NOUN	_	Number=Sing	_	_	_	_
22	assay	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	time	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	ADV	_	PronType=Rel	_	_	_	_
9	CD3	_	PROPN	_	Number=Sing	_	_	_	_
10	antigen	_	VERB	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	signals	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	CD2	_	NOUN	_	Number=Sing	_	_	_	_
16	antigen	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	signals	_	NOUN	_	Number=Plur	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
22	in	_	SCONJ	_	_	_	_	_	_
23	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	emergence	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	AT1	_	PROPN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	AP	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	NF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	kB	_	NOUN	_	Number=Sing	_	_	_	_
45	sites	_	NOUN	_	Number=Plur	_	_	_	_
46	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	promoter	_	NOUN	_	Number=Sing	_	_	_	_
50	/	_	PUNCT	_	_	_	_	_	_
51	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
52	region	_	NOUN	_	Number=Sing	_	_	_	_
53	of	_	ADP	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	IL	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	2	_	NUM	_	NumType=Card	_	_	_	_
58	gene	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cyclosporine	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
7	readily	_	ADV	_	_	_	_	_	_
8	accomplished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
11	practice	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	emergence	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	DNA	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	binding	_	VERB	_	Number=Sing	_	_	_	_
24	proteins	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	normal	_	ADJ	_	Degree=Pos	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	signaled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	via	_	ADP	_	_	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	surface	_	NOUN	_	Number=Sing	_	_	_	_
34	proteins	_	NOUN	_	Number=Plur	_	_	_	_
35	implicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	antigen	_	ADJ	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
40	T	_	NOUN	_	Number=Sing	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	activation	_	NOUN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	T	_	PROPN	_	Number=Sing	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	by	_	ADP	_	_	_	_	_	_
49	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
52	calcium	_	NOUN	_	Number=Sing	_	_	_	_
53	and	_	CCONJ	_	_	_	_	_	_
54	activation	_	NOUN	_	Number=Sing	_	_	_	_
55	of	_	ADP	_	_	_	_	_	_
56	protein	_	NOUN	_	Number=Sing	_	_	_	_
57	kinase	_	NOUN	_	Number=Sing	_	_	_	_
58	C.	_	PROPN	_	Number=Sing	_	_	_	_
59	Document	_	NOUN	_	Number=Sing	_	_	_	_
60	003002298	_	NUM	_	NumType=Card	_	_	_	_
61	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	Monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	type	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Interstitial	_	ADJ	_	Degree=Pos	_	_	_	_
2	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	MMP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	metalloproteinase	_	NOUN	_	Number=Sing	_	_	_	_
11	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	resident	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	connective	_	ADJ	_	Degree=Pos	_	_	_	_
19	tissue	_	NOUN	_	Number=Sing	_	_	_	_
20	turnover	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	cleaves	_	VERB	_	Number=Plur	_	_	_	_
23	type	_	NOUN	_	Number=Sing	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	collagen	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	fibrils	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	catalytic	_	ADJ	_	Degree=Pos	_	_	_	_
3	event	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	rate	_	NOUN	_	Number=Sing	_	_	_	_
6	limiting	_	VERB	_	VerbForm=Ger	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	remodeling	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	tissues	_	NOUN	_	Number=Plur	_	_	_	_
11	rich	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	fibrillar	_	ADJ	_	Degree=Pos	_	_	_	_
14	collagen	_	NOUN	_	Number=Sing	_	_	_	_
15	such	_	ADJ	_	Degree=Pos	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	skin	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	lungs	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	;	_	PUNCT	_	_	_	_	_	_
12	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
13	LPS	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	zymosan	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	yeast	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	wall	_	NOUN	_	Number=Sing	_	_	_	_
21	derivative	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	potent	_	ADJ	_	Degree=Pos	_	_	_	_
25	inducers	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	but	_	CCONJ	_	_	_	_	_	_
33	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
36	fibroblast	_	NOUN	_	Degree=Pos	_	_	_	_
37	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	promoter	_	NOUN	_	Number=Sing	_	_	_	_
3	elements	_	NOUN	_	Number=Plur	_	_	_	_
4	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
5	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	previously	_	ADV	_	_	_	_	_	_
14	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	sought	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	delineate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
21	cis	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	elements	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	transiently	_	ADV	_	_	_	_	_	_
31	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	human	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	U937	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	murine	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	J774	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	lines	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	constructs	_	NOUN	_	Number=Plur	_	_	_	_
3	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	as	_	ADV	_	_	_	_	_	_
5	little	_	ADV	_	Degree=Pos	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	72	_	NUM	_	NumType=Card	_	_	_	_
8	bp	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	5	_	NUM	_	NumType=Card	_	_	_	_
11	'	_	NOUN	_	Number=Plur	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	flanking	_	NOUN	_	Degree=Pos	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	LPS	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	zymosan	_	ADJ	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	induction	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	whereas	_	SCONJ	_	_	_	_	_	_
32	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
33	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
34	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	absolute	_	ADJ	_	Degree=Pos	_	_	_	_
37	requirement	_	NOUN	_	Number=Sing	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
40	elements	_	NOUN	_	Number=Plur	_	_	_	_
41	including	_	VERB	_	VerbForm=Ger	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	polyoma	_	NOUN	_	Number=Sing	_	_	_	_
44	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
45	A	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	binding	_	VERB	_	Number=Sing	_	_	_	_
48	protein	_	NOUN	_	Number=Sing	_	_	_	_
49	-3	_	NUM	_	Number=Sing	_	_	_	_
50	site	_	NOUN	_	Number=Sing	_	_	_	_
51	(	_	PUNCT	_	_	_	_	_	_
52	-	_	SYM	_	_	_	_	_	_
53	83	_	NUM	_	NumType=Card	_	_	_	_
54	to	_	ADP	_	_	_	_	_	_
55	-	_	SYM	_	_	_	_	_	_
56	91	_	NUM	_	NumType=Card	_	_	_	_
57	)	_	PUNCT	_	_	_	_	_	_
58	and	_	CCONJ	_	_	_	_	_	_
59	TTCA	_	PROPN	_	Number=Sing	_	_	_	_
60	sequence	_	NOUN	_	Number=Sing	_	_	_	_
61	(	_	PUNCT	_	_	_	_	_	_
62	-	_	SYM	_	_	_	_	_	_
63	102	_	NUM	_	NumType=Card	_	_	_	_
64	to	_	ADP	_	_	_	_	_	_
65	-	_	SYM	_	_	_	_	_	_
66	105	_	NUM	_	NumType=Card	_	_	_	_
67	)	_	PUNCT	_	_	_	_	_	_
68	in	_	ADP	_	_	_	_	_	_
69	both	_	CCONJ	_	_	_	_	_	_
70	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
71	cells	_	NOUN	_	Number=Plur	_	_	_	_
72	and	_	CCONJ	_	_	_	_	_	_
73	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
74	.	_	PUNCT	_	_	_	_	_	_

1	Mutagenesis	_	PROPN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	activator	_	NOUN	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	[	_	PUNCT	_	_	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	]	_	PUNCT	_	_	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	-	_	SYM	_	_	_	_	_	_
16	72	_	NUM	_	NumType=Card	_	_	_	_
17	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	basal	_	ADJ	_	Number=Sing	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	LPS	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	zymosan	_	NOUN	_	Number=Sing	_	_	_	_
25	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	while	_	SCONJ	_	_	_	_	_	_
28	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	like	_	ADJ	_	Degree=Pos	_	_	_	_
36	site	_	NOUN	_	Number=Sing	_	_	_	_
37	at	_	ADP	_	_	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	20	_	NUM	_	NumType=Card	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	-	_	SYM	_	_	_	_	_	_
42	10	_	NUM	_	NumType=Card	_	_	_	_
43	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
44	no	_	DET	_	_	_	_	_	_
45	effect	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	extracts	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	LPS	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	zymosan	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	strong	_	ADJ	_	Degree=Pos	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	gel	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	shift	_	NOUN	_	Number=Sing	_	_	_	_
21	analysis	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	supershift	_	NOUN	_	Number=Sing	_	_	_	_
25	analysis	_	NOUN	_	Number=Sing	_	_	_	_
26	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	AP	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	complexes	_	NOUN	_	Number=Plur	_	_	_	_
32	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	specific	_	ADJ	_	Degree=Pos	_	_	_	_
34	members	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	both	_	CCONJ	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	jun	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	fos	_	ADP	_	_	_	_	_	_
41	gene	_	NOUN	_	Number=Sing	_	_	_	_
42	families	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	contrast	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	most	_	ADJ	_	Degree=Sup	_	_	_	_
10	LPS	_	NOUN	_	Number=Sing	_	_	_	_
11	effects	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	not	_	ADV	_	_	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	LPS	_	NOUN	_	Number=Sing	_	_	_	_
26	induction	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	macrophagelike	_	ADJ	_	Degree=Pos	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	as	_	SCONJ	_	_	_	_	_	_
4	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
9	ester	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	wall	_	NOUN	_	Number=Sing	_	_	_	_
19	derivatives	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	bacteria	_	NOUN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	yeast	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	largely	_	ADV	_	_	_	_	_	_
26	independent	_	ADJ	_	Degree=Pos	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	sequences	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002307	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Salicylates	_	PROPN	_	Number=Plur	_	_	_	_
2	inhibit	_	VERB	_	Number=Sing	_	_	_	_
3	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	tissue	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	plasma	_	NOUN	_	Number=Sing	_	_	_	_
4	Factor	_	NOUN	_	Number=Sing	_	_	_	_
5	VII	_	NUM	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	VIIa	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	tissue	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	TF	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	initiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	coagulation	_	NOUN	_	Number=Sing	_	_	_	_
19	protease	_	NOUN	_	Number=Sing	_	_	_	_
20	cascades	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	TF	_	ADP	_	_	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	SCONJ	_	_	_	_	_	_
4	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
5	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	thrombotic	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	complications	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	variety	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	diseases	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	TF	_	NOUN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
14	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	LPS	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	p65	_	NOUN	_	Number=Sing	_	_	_	_
26	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	TF	_	PROPN	_	Number=Sing	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	family	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	agents	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	salicylates	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	LPS	_	PROPN	_	Number=Sing	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	TF	_	ADJ	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	TF	_	ADJ	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
32	THP	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	at	_	ADP	_	_	_	_	_	_
37	clinically	_	ADV	_	_	_	_	_	_
38	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
39	doses	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	sodium	_	NOUN	_	Number=Sing	_	_	_	_
4	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
5	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	LPS	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	degradation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	kappa	_	VERB	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	translocation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	p65	_	NOUN	_	Number=Sing	_	_	_	_
27	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	other	_	ADJ	_	Degree=Pos	_	_	_	_
6	nonsteroidal	_	ADJ	_	Degree=Pos	_	_	_	_
7	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	drugs	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	ibuprofen	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	indomethacin	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
17	LPS	_	PROPN	_	Number=Sing	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	TF	_	PROPN	_	Number=Sing	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	salicylates	_	NOUN	_	Number=Plur	_	_	_	_
6	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	LPS	_	PROPN	_	Number=Sing	_	_	_	_
8	induction	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	TF	_	PROPN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	SCONJ	_	_	_	_	_	_
17	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	translocation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	p65	_	NOUN	_	Number=Sing	_	_	_	_
24	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
3	benefits	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	salicylates	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	treatment	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	several	_	ADJ	_	Degree=Pos	_	_	_	_
11	diseases	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	including	_	VERB	_	VerbForm=Ger	_	_	_	_
14	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	rheumatoid	_	VERB	_	Number=Sing	_	_	_	_
17	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	may	_	AUX	_	VerbForm=Fin	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	related	_	ADJ	_	Degree=Pos	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	ability	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	reduce	_	VERB	_	VerbForm=Inf	_	_	_	_
27	monocyte	_	ADJ	_	Degree=Pos	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002314	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CD30	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	degradation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
7	:	_	PUNCT	_	_	_	_	_	_
8	implications	_	NOUN	_	Number=Plur	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	negative	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	TRAF	_	PROPN	_	Number=Sing	_	_	_	_
14	signaling	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	control	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	survival	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	CD30	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	surface	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	augment	_	VERB	_	VerbForm=Inf	_	_	_	_
11	lymphocyte	_	NOUN	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	survival	_	NOUN	_	Number=Sing	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	ability	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	CD30	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	however	_	ADV	_	_	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	death	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	one	_	NUM	_	NumType=Card	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	effects	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	CD30	_	NOUN	_	Number=Sing	_	_	_	_
11	signal	_	NOUN	_	Number=Sing	_	_	_	_
12	transduction	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	render	_	VERB	_	VerbForm=Inf	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	type	_	NOUN	_	Number=Sing	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	tumor	_	NOUN	_	Number=Sing	_	_	_	_
26	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	receptor	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	TNFR1	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	sensitization	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	TRAF	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	sites	_	NOUN	_	Number=Plur	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	CD30	_	PROPN	_	Number=Sing	_	_	_	_
14	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
15	domain	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	proteins	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	sites	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	TRAF2	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	signal	_	ADJ	_	Number=Sing	_	_	_	_
15	transduction	_	NOUN	_	Number=Sing	_	_	_	_
16	molecule	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	utilized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	TNFR1	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	several	_	ADJ	_	Degree=Pos	_	_	_	_
29	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
30	kinases	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	factors	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	During	_	ADP	_	_	_	_	_	_
2	CD30	_	PROPN	_	Number=Sing	_	_	_	_
3	signal	_	NOUN	_	Number=Sing	_	_	_	_
4	transduction	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	DET	_	_	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
15	domain	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	CD30	_	NOUN	_	Number=Sing	_	_	_	_
18	results	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
22	depletion	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	TRAF1	_	NOUN	_	Number=Sing	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	model	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	CD30	_	PROPN	_	Number=Sing	_	_	_	_
9	limits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	own	_	ADJ	_	Degree=Pos	_	_	_	_
12	ability	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	transduce	_	VERB	_	VerbForm=Inf	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	survival	_	NOUN	_	Number=Sing	_	_	_	_
17	signals	_	NOUN	_	Number=Plur	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	signal	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	depletion	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Depletion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
4	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
7	coassociated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	SCONJ	_	_	_	_	_	_
17	undergoing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
19	during	_	ADP	_	_	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	death	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
25	receptors	_	NOUN	_	Number=Plur	_	_	_	_
26	such	_	ADJ	_	Degree=Pos	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	TNFR1	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	negative	_	ADJ	_	Degree=Pos	_	_	_	_
12	form	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	potentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
19	TNFR1	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
22	death	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	potential	_	ADJ	_	Degree=Pos	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	through	_	ADP	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	CD30	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	as	_	ADV	_	_	_	_	_	_
12	well	_	ADV	_	Degree=Pos	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	other	_	ADJ	_	Degree=Pos	_	_	_	_
15	TRAF	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	members	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	TNFR	_	PROPN	_	Number=Sing	_	_	_	_
22	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	can	_	AUX	_	VerbForm=Fin	_	_	_	_
25	negatively	_	ADV	_	_	_	_	_	_
26	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	survival	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002320	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Calcineurin	_	PROPN	_	Number=Sing	_	_	_	_
2	acts	_	VERB	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	synergy	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	PMA	_	PROPN	_	Number=Sing	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	inactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	kappa	_	VERB	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	MAD3	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B.	_	PROPN	_	Number=Sing	_	_	_	_
22	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	promoter	_	NOUN	_	Number=Sing	_	_	_	_
32	consists	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	several	_	ADJ	_	Degree=Pos	_	_	_	_
35	independent	_	ADJ	_	Degree=Pos	_	_	_	_
36	T	_	PROPN	_	Number=Sing	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	receptor	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	TcR	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
43	elements	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	promoters	_	NOUN	_	Number=Plur	_	_	_	_
5	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	elements	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	inhibitable	_	ADJ	_	Degree=Pos	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	immunosuppressants	_	NOUN	_	Number=Plur	_	_	_	_
14	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
15	A	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	CsA	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	tacrolimus	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	FK	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	506	_	NUM	_	NumType=Card	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Calcineurin	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	Ca2+/calmodulin-dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	FK-506	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	CsA	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
16	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
17	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	TcR	_	PROPN	_	Number=Sing	_	_	_	_
20	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	constitutively	_	ADV	_	_	_	_	_	_
6	active	_	ADJ	_	Degree=Pos	_	_	_	_
7	form	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
10	partially	_	ADV	_	_	_	_	_	_
11	substitutes	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
15	+	_	SYM	_	_	_	_	_	_
16	co-stimulus	_	NOUN	_	Number=Sing	_	_	_	_
17	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	elements	_	NOUN	_	Number=Plur	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2A	_	PROPN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	which	_	PRON	_	PronType=Rel	_	_	_	_
31	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	factors	_	NOUN	_	Number=Plur	_	_	_	_
34	OAP	_	PROPN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	Oct	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	2E	_	PROPN	_	Number=Sing	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	which	_	PRON	_	PronType=Rel	_	_	_	_
46	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
47	NF	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	AT	_	ADP	_	_	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	completely	_	ADV	_	_	_	_	_	_
54	substitutes	_	NOUN	_	Number=Plur	_	_	_	_
55	for	_	ADP	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
58	+	_	SYM	_	_	_	_	_	_
59	co-stimulus	_	NOUN	_	Number=Sing	_	_	_	_
60	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
61	to	_	PART	_	_	_	_	_	_
62	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
63	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
64	NF	_	PROPN	_	Number=Sing	_	_	_	_
65	-	_	PUNCT	_	_	_	_	_	_
66	kappa	_	NOUN	_	Number=Sing	_	_	_	_
67	B	_	NOUN	_	Number=Sing	_	_	_	_
68	-	_	PUNCT	_	_	_	_	_	_
69	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
70	element	_	NOUN	_	Number=Sing	_	_	_	_
71	.	_	PUNCT	_	_	_	_	_	_

1	Calcineurin	_	PROPN	_	Number=Sing	_	_	_	_
2	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	element	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	SCONJ	_	_	_	_	_	_
10	enhancing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	kappa	_	PROPN	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	MAD3	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	thereby	_	ADV	_	_	_	_	_	_
28	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	amount	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	DNA	_	NOUN	_	Number=Sing	_	_	_	_
38	binding	_	NOUN	_	Number=Sing	_	_	_	_
39	activity	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	demonstration	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	vivo	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
15	can	_	AUX	_	VerbForm=Fin	_	_	_	_
16	inactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	suggest	_	VERB	_	VerbForm=Inf	_	_	_	_
23	one	_	NUM	_	NumType=Card	_	_	_	_
24	possible	_	ADJ	_	Degree=Pos	_	_	_	_
25	explanation	_	NOUN	_	Number=Sing	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	toxicities	_	NOUN	_	Number=Plur	_	_	_	_
31	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	FK	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	506	_	NUM	_	NumType=Card	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	CsA	_	PROPN	_	Number=Sing	_	_	_	_
38	by	_	SCONJ	_	_	_	_	_	_
39	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
40	that	_	SCONJ	_	_	_	_	_	_
41	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
42	drugs	_	NOUN	_	Number=Plur	_	_	_	_
43	can	_	AUX	_	VerbForm=Fin	_	_	_	_
44	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
49	activation	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
52	virtually	_	ADV	_	_	_	_	_	_
53	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
54	transcription	_	NOUN	_	Number=Sing	_	_	_	_
55	factor	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002321	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Active	_	ADJ	_	Degree=Pos	_	_	_	_
2	suppression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	class	_	NOUN	_	Number=Sing	_	_	_	_
6	II	_	NUM	_	NumType=Card	_	_	_	_
7	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
10	AIR	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	locus	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	lack	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	major	_	ADJ	_	Degree=Pos	_	_	_	_
21	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
22	complex	_	NOUN	_	Degree=Pos	_	_	_	_
23	class	_	NOUN	_	Number=Sing	_	_	_	_
24	II	_	NUM	_	NumType=Card	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	during	_	ADP	_	_	_	_	_	_
29	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	B	_	ADJ	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	plasma	_	VERB	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
6	control	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	major	_	ADJ	_	Degree=Pos	_	_	_	_
9	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
10	complex	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	MHC	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	class	_	NOUN	_	Number=Sing	_	_	_	_
15	II	_	NUM	_	NumType=Card	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	during	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transition	_	NOUN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	B	_	ADJ	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	plasma	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
29	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Class	_	NOUN	_	Number=Sing	_	_	_	_
2	II	_	NUM	_	NumType=Card	_	_	_	_
3	molecules	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	plasma	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	because	_	ADP	_	_	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	active	_	ADJ	_	Degree=Pos	_	_	_	_
14	suppression	_	NOUN	_	Number=Sing	_	_	_	_
15	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	abrogation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	class	_	NOUN	_	Number=Sing	_	_	_	_
21	II	_	NUM	_	NumType=Card	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	plasma	_	NOUN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	repressor	_	NOUN	_	Number=Sing	_	_	_	_
11	function	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	SIR	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	immune	_	ADJ	_	Degree=Pos	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	act	_	VERB	_	VerbForm=Inf	_	_	_	_
26	directly	_	ADV	_	_	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	class	_	NOUN	_	Number=Sing	_	_	_	_
32	II	_	NUM	_	Number=Sing	_	_	_	_
33	genes	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	but	_	CCONJ	_	_	_	_	_	_
36	instead	_	ADV	_	_	_	_	_	_
37	on	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	AIR	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	gene	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
48	product	_	NOUN	_	Number=Sing	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	class	_	NOUN	_	Number=Sing	_	_	_	_
52	II	_	NUM	_	Number=Sing	_	_	_	_
53	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
54	(	_	PUNCT	_	_	_	_	_	_
55	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
59	fundamental	_	ADJ	_	Degree=Pos	_	_	_	_
60	for	_	ADP	_	_	_	_	_	_
61	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
62	regulation	_	NOUN	_	Number=Sing	_	_	_	_
63	of	_	ADP	_	_	_	_	_	_
64	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
65	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
66	and	_	CCONJ	_	_	_	_	_	_
67	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
68	expression	_	NOUN	_	Number=Sing	_	_	_	_
69	of	_	ADP	_	_	_	_	_	_
70	MHC	_	PROPN	_	Number=Sing	_	_	_	_
71	class	_	NOUN	_	Number=Sing	_	_	_	_
72	II	_	NUM	_	Number=Sing	_	_	_	_
73	genes	_	NOUN	_	Number=Plur	_	_	_	_
74	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	unambiguously	_	ADV	_	_	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	fact	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	plasmacytoma	_	NOUN	_	Number=Sing	_	_	_	_
10	x	_	NOUN	_	_	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	hybrids	_	NOUN	_	Number=Plur	_	_	_	_
14	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	AIR	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	locus	_	NOUN	_	Number=Sing	_	_	_	_
20	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	express	_	VERB	_	VerbForm=Inf	_	_	_	_
29	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	specific	_	ADJ	_	Degree=Pos	_	_	_	_
32	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Transfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
5	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
9	coding	_	NOUN	_	Number=Sing	_	_	_	_
10	sequence	_	NOUN	_	Number=Sing	_	_	_	_
11	under	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	control	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	restores	_	NOUN	_	Number=Plur	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	MHC	_	PROPN	_	Number=Sing	_	_	_	_
23	class	_	NOUN	_	Number=Sing	_	_	_	_
24	II	_	NUM	_	Number=Sing	_	_	_	_
25	genes	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	hybrids	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	de	_	X	_	Number=Sing	_	_	_	_
34	novo	_	X	_	Number=Sing	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	mouse	_	NOUN	_	Number=Sing	_	_	_	_
38	MHC	_	PROPN	_	Number=Sing	_	_	_	_
39	class	_	NOUN	_	Number=Sing	_	_	_	_
40	II	_	NUM	_	Number=Sing	_	_	_	_
41	genes	_	NOUN	_	Number=Plur	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	both	_	CCONJ	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	mouse	_	NOUN	_	Number=Sing	_	_	_	_
46	plasmacytoma	_	NOUN	_	Number=Sing	_	_	_	_
47	cell	_	NOUN	_	Number=Sing	_	_	_	_
48	line	_	NOUN	_	Number=Sing	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	hybrids	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	confirm	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	extend	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	notion	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	functional	_	ADJ	_	Degree=Pos	_	_	_	_
11	conservation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	AIR	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	product	_	NOUN	_	Number=Sing	_	_	_	_
19	across	_	ADP	_	_	_	_	_	_
20	species	_	NOUN	_	Number=Plur	_	_	_	_
21	barriers	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	hybrids	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	surface	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	HLA	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	DQ	_	NOUN	_	Number=Sing	_	_	_	_
19	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	result	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	attributable	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	lack	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HLA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	DQ	_	NOUN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	DQ	_	PROPN	_	Number=Sing	_	_	_	_
16	beta	_	NOUN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	because	_	SCONJ	_	_	_	_	_	_
20	both	_	DET	_	_	_	_	_	_
21	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	present	_	ADJ	_	Degree=Pos	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	hybrids	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	although	_	SCONJ	_	_	_	_	_	_
32	at	_	ADP	_	_	_	_	_	_
33	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	levels	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	further	_	ADV	_	_	_	_	_	_
4	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
6	previous	_	ADJ	_	Degree=Pos	_	_	_	_
7	observations	_	NOUN	_	Number=Plur	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	HLA	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	DQ	_	NOUN	_	Number=Sing	_	_	_	_
20	class	_	NOUN	_	Number=Sing	_	_	_	_
21	II	_	NUM	_	Number=Sing	_	_	_	_
22	subset	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	may	_	AUX	_	VerbForm=Fin	_	_	_	_
26	be	_	AUX	_	VerbForm=Inf	_	_	_	_
27	thus	_	ADV	_	_	_	_	_	_
28	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	at	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
32	level	_	NOUN	_	Number=Sing	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	CIITA	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	independent	_	ADJ	_	Degree=Pos	_	_	_	_
38	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002324	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Suppression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	normal	_	ADJ	_	Degree=Pos	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	supernatant	_	ADJ	_	Degree=Pos	_	_	_	_
13	fluid	_	NOUN	_	Number=Sing	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	renal	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	carcinomas	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	patients	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	renal	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	RCC	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	show	_	VERB	_	VerbForm=Inf	_	_	_	_
13	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	immune	_	ADJ	_	Degree=Pos	_	_	_	_
15	function	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	impaired	_	VERB	_	Degree=Pos	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	determined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	suppression	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	RCC	_	PROPN	_	Number=Sing	_	_	_	_
15	patient	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	determined	_	VERB	_	Degree=Pos	_	_	_	_
18	whether	_	SCONJ	_	_	_	_	_	_
19	supernatant	_	ADJ	_	Degree=Pos	_	_	_	_
20	fluid	_	NOUN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	RCC	_	PROPN	_	Number=Sing	_	_	_	_
23	explants	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	RCC	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	S	_	X	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	same	_	ADJ	_	Degree=Pos	_	_	_	_
32	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
37	suppression	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	normal	_	ADJ	_	Degree=Pos	_	_	_	_
40	T	_	NOUN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	that	_	PRON	_	PronType=Rel	_	_	_	_
43	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
44	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	patient	_	ADJ	_	Number=Sing	_	_	_	_
47	T	_	NOUN	_	Number=Sing	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	pattern	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	RCC	_	PROPN	_	Number=Sing	_	_	_	_
13	patient	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	as	_	SCONJ	_	_	_	_	_	_
17	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
20	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	normal	_	ADJ	_	Degree=Pos	_	_	_	_
27	volunteers	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	some	_	DET	_	_	_	_	_	_
3	patients	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	no	_	DET	_	_	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	RelA	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	NFkappaB1	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	while	_	SCONJ	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	others	_	NOUN	_	Number=Plur	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	binding	_	VERB	_	Number=Sing	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	modestly	_	ADV	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	duration	_	NOUN	_	Number=Sing	_	_	_	_
30	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
31	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	degraded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	normally	_	ADV	_	_	_	_	_	_
5	following	_	VERB	_	VerbForm=Ger	_	_	_	_
6	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	normal	_	ADJ	_	Degree=Pos	_	_	_	_
10	controls	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	RCC	_	NOUN	_	Number=Sing	_	_	_	_
16	patients	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	RCC	_	PROPN	_	Number=Sing	_	_	_	_
2	-S	_	PUNCT	_	Number=Sing	_	_	_	_
3	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	RelA	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB1	_	NOUN	_	Number=Sing	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
18	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	localization	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	RelA	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB1	_	NOUN	_	Number=Sing	_	_	_	_
31	binding	_	NOUN	_	Number=Sing	_	_	_	_
32	complexes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	RCC	_	PROPN	_	Number=Sing	_	_	_	_
6	-S	_	PROPN	_	_	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	normal	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	same	_	ADJ	_	Degree=Pos	_	_	_	_
15	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	impaired	_	VERB	_	Degree=Pos	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	T	_	PROPN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	RCC	_	NOUN	_	Number=Sing	_	_	_	_
30	patient	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	suppression	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	RCC	_	PROPN	_	Number=Sing	_	_	_	_
11	-S	_	PROPN	_	Number=Sing	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	immunosuppression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	host	_	NOUN	_	Number=Sing	_	_	_	_
19	immunity	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002325	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	isotype-specific	_	ADJ	_	Degree=Pos	_	_	_	_
3	activator	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	major	_	ADJ	_	Degree=Pos	_	_	_	_
6	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
7	complex	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	MHC	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	class	_	NOUN	_	Number=Sing	_	_	_	_
12	II	_	NUM	_	Number=Sing	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	independent	_	ADJ	_	Degree=Pos	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	class	_	NOUN	_	Number=Sing	_	_	_	_
19	II	_	NUM	_	NumType=Card	_	_	_	_
20	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Patients	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	one	_	NUM	_	NumType=Card	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	major	_	ADJ	_	Degree=Pos	_	_	_	_
7	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
8	complex	_	NOUN	_	Degree=Pos	_	_	_	_
9	class	_	NOUN	_	Number=Sing	_	_	_	_
10	II	_	NUM	_	NumType=Card	_	_	_	_
11	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
13	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	mutations	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	class	_	NOUN	_	Number=Sing	_	_	_	_
20	II	_	NUM	_	NumType=Card	_	_	_	_
21	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	which	_	PRON	_	PronType=Rel	_	_	_	_
27	coordinately	_	ADV	_	_	_	_	_	_
28	controls	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	three	_	NUM	_	NumType=Card	_	_	_	_
34	major	_	ADJ	_	Degree=Pos	_	_	_	_
35	human	_	ADJ	_	Degree=Pos	_	_	_	_
36	class	_	NOUN	_	Number=Sing	_	_	_	_
37	II	_	PROPN	_	Number=Sing	_	_	_	_
38	genes	_	NOUN	_	Number=Plur	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	HLA	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	DR	_	PROPN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	DQ	_	PROPN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	DP	_	PROPN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	experimentally	_	ADV	_	_	_	_	_	_
5	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	B-	_	PUNCT	_	_	_	_	_	_
7	lymphoblastoid	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	line	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	clone	_	NOUN	_	Number=Sing	_	_	_	_
12	13	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	expresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	high	_	ADJ	_	Degree=Pos	_	_	_	_
16	levels	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	HLADQ	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	absence	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	HLA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	DR	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	HLA	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	DP	_	PROPN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	despite	_	ADP	_	_	_	_	_	_
32	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
33	mapping	_	NOUN	_	Number=Sing	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	complementation	_	NOUN	_	Number=Sing	_	_	_	_
36	analysis	_	NOUN	_	Number=Sing	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
39	group	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	possible	_	ADJ	_	Degree=Pos	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	one	_	NUM	_	NumType=Card	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	clone	_	NOUN	_	Number=Sing	_	_	_	_
9	13	_	NUM	_	NumType=Card	_	_	_	_
10	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
11	alleles	_	NOUN	_	Number=Plur	_	_	_	_
12	bore	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	mutation	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	allowed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	HLA	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	DQ	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	not	_	ADV	_	_	_	_	_	_
23	HLA	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	DR	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	DP	_	PROPN	_	Number=Sing	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Alternatively	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	another	_	DET	_	_	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	might	_	AUX	_	VerbForm=Fin	_	_	_	_
11	control	_	VERB	_	VerbForm=Inf	_	_	_	_
12	HLA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	DQ	_	PROPN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
9	cDNAs	_	NOUN	_	Number=Plur	_	_	_	_
10	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	reverse	_	NOUN	_	Number=Sing	_	_	_	_
13	transcriptase	_	NOUN	_	Number=Sing	_	_	_	_
14	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
15	chain	_	NOUN	_	Number=Sing	_	_	_	_
16	reaction	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	clone	_	NOUN	_	Number=Sing	_	_	_	_
19	13	_	NUM	_	NumType=Card	_	_	_	_
20	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	restore	_	VERB	_	VerbForm=Inf	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	HLA	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	DQ	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	another	_	DET	_	_	_	_	_	_
30	CIITA	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	line	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	RJ2.2.5	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	no	_	DET	_	_	_	_	_	_
5	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	clone	_	ADJ	_	Number=Sing	_	_	_	_
11	13	_	NUM	_	NumType=Card	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	extracts	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	somatic	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	fusion	_	NOUN	_	Number=Sing	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	clone	_	NOUN	_	Number=Sing	_	_	_	_
9	13	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	RJ2.2.5	_	NUM	_	NumType=Card	_	_	_	_
12	restored	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	HLA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	DQ	_	NOUN	_	Number=Sing	_	_	_	_
19	haplotype	_	NOUN	_	Number=Sing	_	_	_	_
20	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	RJ2.2.5	_	NUM	_	NumType=Card	_	_	_	_
24	DQB	_	NOUN	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	existence	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	HLA	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	DQ	_	NOUN	_	Number=Sing	_	_	_	_
14	isotype	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	trans	_	NOUN	_	Number=Plur	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	acting	_	VERB	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	which	_	DET	_	PronType=Rel	_	_	_	_
23	functions	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	independently	_	ADV	_	_	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002328	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
2	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	MHC	_	PROPN	_	Number=Sing	_	_	_	_
7	class	_	NOUN	_	Number=Sing	_	_	_	_
8	II	_	NUM	_	Number=Sing	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	mouse	_	NOUN	_	Number=Sing	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	long	_	ADV	_	Degree=Pos	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	puzzle	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	_	_	_	_	_
8	MHC	_	PROPN	_	Number=Sing	_	_	_	_
9	class	_	NOUN	_	Number=Sing	_	_	_	_
10	II	_	NUM	_	NumType=Card	_	_	_	_
11	molecules	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	after	_	ADP	_	_	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	mouse	_	NOUN	_	Number=Sing	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	;	_	PUNCT	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	play	_	VERB	_	VerbForm=Inf	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	role	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	immune	_	ADJ	_	Number=Sing	_	_	_	_
40	response	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	MHC	_	PROPN	_	Number=Sing	_	_	_	_
4	class	_	NOUN	_	Number=Sing	_	_	_	_
5	II	_	NUM	_	NumType=Card	_	_	_	_
6	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	major	_	ADJ	_	Degree=Pos	_	_	_	_
17	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	IFN	_	PROPN	_	Number=Sing	_	_	_	_
25	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	MHC	_	PROPN	_	Number=Sing	_	_	_	_
29	class	_	NOUN	_	Number=Sing	_	_	_	_
30	II	_	NUM	_	Number=Sing	_	_	_	_
31	genes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	MHC	_	PROPN	_	Number=Sing	_	_	_	_
10	class	_	NOUN	_	Number=Sing	_	_	_	_
11	II	_	NUM	_	Number=Sing	_	_	_	_
12	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
14	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
15	while	_	SCONJ	_	_	_	_	_	_
16	MHC	_	PROPN	_	Number=Sing	_	_	_	_
17	class	_	NOUN	_	Number=Sing	_	_	_	_
18	II	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	negative	_	ADJ	_	Degree=Pos	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	mouse	_	NOUN	_	Number=Sing	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	not	_	PART	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	MHC	_	PROPN	_	Number=Sing	_	_	_	_
5	class	_	NOUN	_	Number=Sing	_	_	_	_
6	II	_	NUM	_	Number=Sing	_	_	_	_
7	genes	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	mouse	_	NOUN	_	Number=Sing	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	reconstituted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	upon	_	ADP	_	_	_	_	_	_
16	transfection	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	CIITA	_	NOUN	_	Number=Sing	_	_	_	_
21	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
9	explains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	lack	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	MHC	_	PROPN	_	Number=Sing	_	_	_	_
18	class	_	NOUN	_	Number=Sing	_	_	_	_
19	II	_	NUM	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	mouse	_	NOUN	_	Number=Sing	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	respectively	_	ADV	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002330	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Silencing	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	fetal	_	ADJ	_	Number=Sing	_	_	_	_
5	globin	_	NOUN	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	impaired	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	absence	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	adult	_	NOUN	_	Number=Sing	_	_	_	_
15	beta-globin	_	NOUN	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	activator	_	NOUN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Globin	_	ADJ	_	Degree=Pos	_	_	_	_
2	genes	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	subject	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	tissue	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
11	stage	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	switch	_	NOUN	_	Number=Sing	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	fetal	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	adult	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	globin	_	NOUN	_	Degree=Pos	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	within	_	ADP	_	_	_	_	_	_
20	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
21	precursor	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	adult	_	NOUN	_	Number=Sing	_	_	_	_
26	lineage	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Previously	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	others	_	NOUN	_	Number=Plur	_	_	_	_
5	showed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	disruption	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	zinc	_	NOUN	_	Number=Sing	_	_	_	_
13	finger	_	NOUN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	erythroid	_	VERB	_	Number=Sing	_	_	_	_
17	Kruppel	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	like	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	beta	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	globin	_	NOUN	_	Degree=Pos	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	mice	_	NOUN	_	Number=Plur	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	presumably	_	ADV	_	_	_	_	_	_
39	through	_	ADP	_	_	_	_	_	_
40	interaction	_	NOUN	_	Number=Sing	_	_	_	_
41	with	_	ADP	_	_	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	high	_	ADJ	_	Degree=Pos	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	affinity	_	NOUN	_	Number=Sing	_	_	_	_
46	binding	_	NOUN	_	Number=Sing	_	_	_	_
47	site	_	NOUN	_	Number=Sing	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
51	promoter	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	gamma	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	globin	_	NOUN	_	Degree=Pos	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	interbred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
21	heterozygotes	_	NOUN	_	Number=Plur	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	+/-	_	SYM	_	_	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	with	_	SCONJ	_	_	_	_	_	_
26	mice	_	NOUN	_	Number=Plur	_	_	_	_
27	harboring	_	VERB	_	VerbForm=Ger	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	beta-globin	_	NOUN	_	Number=Sing	_	_	_	_
31	yeast	_	NOUN	_	Number=Sing	_	_	_	_
32	artificial	_	ADJ	_	Degree=Pos	_	_	_	_
33	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
34	transgene	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	absence	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	while	_	SCONJ	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	beta-globin	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	dramatically	_	ADV	_	_	_	_	_	_
16	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	gamma	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	globin	_	NOUN	_	Degree=Pos	_	_	_	_
21	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
22	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	elevated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	approximately	_	ADV	_	_	_	_	_	_
25	5	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	fold	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Impaired	_	ADJ	_	Degree=Pos	_	_	_	_
2	silencing	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	gamma	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	globin	_	NOUN	_	Degree=Pos	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	identifies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	participating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	quantitatively	_	ADV	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	gamma	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	globin	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	beta	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	globin	_	PROPN	_	Number=Sing	_	_	_	_
26	switch	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	compatible	_	ADJ	_	Degree=Pos	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	competitive	_	ADJ	_	Degree=Pos	_	_	_	_
8	model	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	switching	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
14	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	adult	_	ADJ	_	Number=Sing	_	_	_	_
17	stage	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	interaction	_	NOUN	_	Number=Sing	_	_	_	_
21	between	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	beta	_	NOUN	_	Number=Sing	_	_	_	_
24	-globin	_	NOUN	_	Degree=Pos	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	locus	_	NOUN	_	Number=Sing	_	_	_	_
30	control	_	NOUN	_	Number=Sing	_	_	_	_
31	region	_	NOUN	_	Number=Sing	_	_	_	_
32	that	_	PRON	_	PronType=Rel	_	_	_	_
33	excludes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	gamma	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	globin	_	NOUN	_	Degree=Pos	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002336	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Membrane	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	lymphotoxin	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	natural	_	ADJ	_	Degree=Pos	_	_	_	_
7	killer	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	via	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	pathway	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	complement	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	small	_	ADJ	_	Degree=Pos	_	_	_	_
8	animal	_	NOUN	_	Number=Sing	_	_	_	_
9	models	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	xenotransplantation	_	NOUN	_	Number=Sing	_	_	_	_
12	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	graft	_	NOUN	_	Number=Sing	_	_	_	_
15	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	natural	_	ADJ	_	Degree=Pos	_	_	_	_
18	killer	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	NK	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	EC	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	NK	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	porcine	_	NOUN	_	Number=Sing	_	_	_	_
11	EC	_	PROPN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vitro	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	DET	_	PronType=Rel	_	_	_	_
16	results	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
19	molecule	_	NOUN	_	Degree=Pos	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
23	secretion	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NK	_	PROPN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	NK92	_	PROPN	_	Number=Sing	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	define	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	molecular	_	NOUN	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	basis	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	NK	_	PROPN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	EC	_	NOUN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	EC	_	PROPN	_	Number=Sing	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	either	_	CCONJ	_	_	_	_	_	_
8	reporter	_	NOUN	_	Number=Sing	_	_	_	_
9	constructs	_	NOUN	_	Number=Plur	_	_	_	_
10	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	either	_	CCONJ	_	_	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	E-selectin	_	PROPN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	8	_	NUM	_	NumType=Card	_	_	_	_
25	promoters	_	NOUN	_	Number=Plur	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	negative	_	ADJ	_	Degree=Pos	_	_	_	_
8	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	I	_	NOUN	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TNFRI	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	vector	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	co	_	X	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	transfected	_	VERB	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
25	studies	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Forty	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	eight	_	NUM	_	NumType=Card	_	_	_	_
4	hours	_	NOUN	_	Number=Plur	_	_	_	_
5	after	_	ADP	_	_	_	_	_	_
6	transfection	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	EC	_	PROPN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	NK	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	NK	_	PROPN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	membrane	_	NOUN	_	Number=Sing	_	_	_	_
18	extracts	_	NOUN	_	Number=Plur	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	7	_	NUM	_	NumType=Card	_	_	_	_
21	hr	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
29	assay	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	Co	_	X	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	culture	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NK	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	EC	_	PROPN	_	Number=Sing	_	_	_	_
10	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	E-selectin	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	8	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	NK	_	PROPN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	membrane	_	NOUN	_	Number=Sing	_	_	_	_
4	extracts	_	NOUN	_	Number=Plur	_	_	_	_
5	retained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	capacity	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	EC	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	translocation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	p50	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	p65	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blotting	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NK	_	PROPN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	membrane	_	NOUN	_	Number=Sing	_	_	_	_
8	extracts	_	NOUN	_	Number=Plur	_	_	_	_
9	detected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	presence	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Lymphotoxin	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	LTalpha	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	tumor	_	NOUN	_	Number=Sing	_	_	_	_
22	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	LTalpha	_	PROPN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	secreted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	NK	_	PROPN	_	Number=Sing	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	EC	_	PROPN	_	Number=Sing	_	_	_	_
10	co-cultures	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Co	_	X	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	transfection	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	negative	_	ADJ	_	Degree=Pos	_	_	_	_
8	mutant	_	NOUN	_	Number=Sing	_	_	_	_
9	TNFRI	_	PROPN	_	Number=Sing	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	EC	_	PROPN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	NK	_	PROPN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	membrane	_	NOUN	_	Number=Sing	_	_	_	_
17	extracts	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	NK	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	80	_	NUM	_	NumType=Card	_	_	_	_
24	%	_	SYM	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	47	_	NUM	_	NumType=Card	_	_	_	_
27	%	_	SYM	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	respectively	_	ADV	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	same	_	ADJ	_	Degree=Pos	_	_	_	_
3	pattern	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	using	_	VERB	_	VerbForm=Ger	_	_	_	_
9	anti-human	_	ADJ	_	Degree=Pos	_	_	_	_
10	LT	_	PROPN	_	Number=Sing	_	_	_	_
11	sera	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Human	_	ADJ	_	Degree=Pos	_	_	_	_
4	NK	_	PROPN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	membrane	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	bound	_	ADJ	_	Degree=Pos	_	_	_	_
9	LT	_	NOUN	_	Number=Sing	_	_	_	_
10	signals	_	NOUN	_	Number=Plur	_	_	_	_
11	across	_	ADP	_	_	_	_	_	_
12	species	_	NOUN	_	Number=Plur	_	_	_	_
13	via	_	ADP	_	_	_	_	_	_
14	TNFRI	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	translocation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	E	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	selectin	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	8	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	which	_	DET	_	PronType=Rel	_	_	_	_
35	results	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	EC	_	NOUN	_	Number=Sing	_	_	_	_
38	activation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	discrepancy	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	degree	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	membrane	_	NOUN	_	Number=Sing	_	_	_	_
10	extracts	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	NK	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
16	TNFRI	_	PROPN	_	Number=Sing	_	_	_	_
17	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	additional	_	ADJ	_	Degree=Pos	_	_	_	_
20	pathways	_	NOUN	_	Number=Plur	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	utilized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	NK	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
28	EC	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002346	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	only	_	ADV	_	_	_	_	_	_
5	partially	_	ADV	_	_	_	_	_	_
6	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Barr	_	PROPN	_	Number=Sing	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	latent	_	ADJ	_	Degree=Pos	_	_	_	_
12	membrane	_	NOUN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	B	_	ADJ	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	latent	_	ADJ	_	Degree=Pos	_	_	_	_
3	membrane	_	NOUN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Barr	_	PROPN	_	Number=Sing	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	EBV	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	EBV	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	causes	_	VERB	_	Number=Plur	_	_	_	_
30	tumorigenic	_	ADJ	_	Degree=Pos	_	_	_	_
31	transformation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	lines	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
5	changes	_	NOUN	_	Number=Plur	_	_	_	_
6	resembling	_	VERB	_	VerbForm=Ger	_	_	_	_
7	B	_	NOUN	_	Degree=Pos	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	such	_	ADJ	_	Degree=Pos	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	size	_	NOUN	_	Number=Sing	_	_	_	_
15	increase	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	up	_	ADP	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	surface	_	NOUN	_	Number=Sing	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	markers	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
2	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	two	_	NUM	_	NumType=Card	_	_	_	_
4	domains	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	one	_	NUM	_	NumType=Card	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	interactions	_	NOUN	_	Number=Plur	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	TRAF	_	NOUN	_	Number=Sing	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	other	_	ADJ	_	Degree=Pos	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	TRADD	_	NOUN	_	Number=Sing	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	purpose	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	present	_	ADJ	_	Degree=Pos	_	_	_	_
6	study	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	importance	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	up	_	ADP	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	regulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	markers	_	NOUN	_	Number=Plur	_	_	_	_
28	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	CD71	_	NOUN	_	Number=Sing	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
8	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
17	promoters	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	can	_	AUX	_	VerbForm=Fin	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	completely	_	ADV	_	_	_	_	_	_
26	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
32	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
33	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
34	mutant	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	CD71	_	PROPN	_	Number=Sing	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	nevertheless	_	ADV	_	_	_	_	_	_
8	up	_	ADP	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	primary	_	ADJ	_	Degree=Pos	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
23	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	size	_	NOUN	_	Number=Sing	_	_	_	_
8	increase	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	primary	_	ADJ	_	Degree=Pos	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	unaffected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	concluded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	even	_	ADV	_	_	_	_	_	_
6	when	_	ADV	_	PronType=Int	_	_	_	_
7	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	unable	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	still	_	ADV	_	_	_	_	_	_
19	capable	_	ADJ	_	Degree=Pos	_	_	_	_
20	of	_	SCONJ	_	_	_	_	_	_
21	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	certain	_	ADJ	_	Degree=Pos	_	_	_	_
23	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	B	_	ADJ	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	strongly	_	ADV	_	_	_	_	_	_
30	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
33	can	_	AUX	_	VerbForm=Fin	_	_	_	_
34	also	_	ADV	_	_	_	_	_	_
35	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	independently	_	ADV	_	_	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002347	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Potent	_	ADJ	_	Degree=Pos	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	antiproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
6	activities	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	20	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	methyl	_	ADJ	_	Number=Sing	_	_	_	_
11	analogues	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	1,25	_	NUM	_	NumType=Card	_	_	_	_
14	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
15	D3.	_	VERB	_	Number=Sing	_	_	_	_
16	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	biological	_	ADJ	_	Degree=Pos	_	_	_	_
18	active	_	ADJ	_	Degree=Pos	_	_	_	_
19	form	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
22	D3	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	1,25	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
27	D3	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	VD	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
34	growth	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	hormone	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	interesting	_	ADJ	_	Degree=Pos	_	_	_	_
8	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
9	potential	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	hypercalcemia	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	side	_	NOUN	_	Degree=Pos	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	caused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	VD	_	PROPN	_	Number=Sing	_	_	_	_
14	's	_	PART	_	_	_	_	_	_
15	classical	_	ADJ	_	Degree=Pos	_	_	_	_
16	action	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	calcium	_	NOUN	_	Number=Sing	_	_	_	_
22	homeostasis	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	made	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	need	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	VD	_	NOUN	_	Number=Sing	_	_	_	_
7	analogues	_	NOUN	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	selectively	_	ADV	_	_	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	properties	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	20	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	epi	_	PROPN	_	Number=Sing	_	_	_	_
6	analogues	_	NOUN	_	Number=Plur	_	_	_	_
7	pointed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	out	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	importance	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	carbon	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	20	_	NUM	_	NumType=Card	_	_	_	_
16	position	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	development	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	20	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	methyl	_	NOUN	_	Number=Sing	_	_	_	_
26	derivatives	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	VD	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	VERB	_	Number=Sing	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	biological	_	ADJ	_	Degree=Pos	_	_	_	_
6	properties	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	compounds	_	NOUN	_	Number=Plur	_	_	_	_
10	ZK161422	_	NUM	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	ZK157202	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	20	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	methyl	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	20	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	methyl	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	23	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	eneanalogues	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	respectively	_	ADV	_	_	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
33	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	comparison	_	NOUN	_	Number=Sing	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	VD	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	compounds	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	about	_	ADV	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
8	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
9	affinity	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	VD	_	NOUN	_	Number=Sing	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	VDR	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	than	_	ADP	_	_	_	_	_	_
18	VD	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	VD	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
8	antiproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	up	_	ADP	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	30	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
16	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
20	blood	_	NOUN	_	Number=Sing	_	_	_	_
21	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	even	_	ADV	_	_	_	_	_	_
25	up	_	ADP	_	_	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	300	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
30	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
31	on	_	ADP	_	_	_	_	_	_
32	human	_	ADJ	_	Degree=Pos	_	_	_	_
33	breast	_	NOUN	_	Number=Sing	_	_	_	_
34	cancer	_	NOUN	_	Number=Sing	_	_	_	_
35	MCF	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	7	_	NUM	_	NumType=Card	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	hypercalcemic	_	ADJ	_	Degree=Pos	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	ZK157202	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	fold	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	ZK161422	_	PROPN	_	Number=Sing	_	_	_	_
15	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	same	_	ADJ	_	Degree=Pos	_	_	_	_
18	calcium	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	mobilizing	_	NOUN	_	VerbForm=Ger	_	_	_	_
21	potency	_	NOUN	_	Number=Sing	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	VD	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	ZK161422	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	but	_	CCONJ	_	_	_	_	_	_
6	not	_	ADV	_	_	_	_	_	_
7	ZK157202	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	preference	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	VD	_	NOUN	_	Number=Sing	_	_	_	_
20	response	_	NOUN	_	Number=Sing	_	_	_	_
21	element	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	palindromic	_	ADJ	_	Degree=Pos	_	_	_	_
25	arrangement	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	two	_	NUM	_	NumType=Card	_	_	_	_
28	hexameric	_	ADJ	_	Degree=Pos	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	sites	_	NOUN	_	Number=Plur	_	_	_	_
32	spaced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	9	_	NUM	_	NumType=Card	_	_	_	_
35	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	IP9	_	X	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	rather	_	ADV	_	_	_	_	_	_
40	than	_	ADP	_	_	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	activation	_	NOUN	_	Number=Sing	_	_	_	_
43	from	_	ADP	_	_	_	_	_	_
44	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
45	response	_	NOUN	_	Number=Sing	_	_	_	_
46	element	_	NOUN	_	Number=Sing	_	_	_	_
47	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	by	_	ADP	_	_	_	_	_	_
49	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
50	direct	_	ADJ	_	Degree=Pos	_	_	_	_
51	repeat	_	NOUN	_	Number=Sing	_	_	_	_
52	spaced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
53	by	_	ADP	_	_	_	_	_	_
54	3	_	NUM	_	NumType=Card	_	_	_	_
55	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
56	(	_	PUNCT	_	_	_	_	_	_
57	DR3	_	NOUN	_	Number=Sing	_	_	_	_
58	)	_	PUNCT	_	_	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	observation	_	NOUN	_	Number=Sing	_	_	_	_
3	supports	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	model	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	which	_	DET	_	PronType=Rel	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	selectivity	_	NOUN	_	Number=Sing	_	_	_	_
11	reflects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	selectively	_	ADV	_	_	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	antiproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
16	effect	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	VD	_	NOUN	_	Number=Sing	_	_	_	_
19	analogues	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002355	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	bifunctional	_	ADJ	_	Degree=Pos	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Jun	_	PROPN	_	Number=Sing	_	_	_	_
8	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
9	family	_	NOUN	_	Number=Sing	_	_	_	_
10	members	_	NOUN	_	Number=Plur	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Interaction	_	NOUN	_	Number=Sing	_	_	_	_
2	between	_	ADP	_	_	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_
5	C	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	PKC	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	GR	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	mediated	_	VERB	_	Degree=Pos	_	_	_	_
18	signaling	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	ability	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	PKC	_	PROPN	_	Number=Sing	_	_	_	_
27	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
28	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
29	ester	_	NOUN	_	Number=Sing	_	_	_	_
30	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	13	_	NUM	_	NumType=Card	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	acetate	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	TPA	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
40	GR	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
43	transcription	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	mouse	_	NOUN	_	Number=Sing	_	_	_	_
47	mammary	_	ADJ	_	Number=Sing	_	_	_	_
48	tumor	_	NOUN	_	Number=Sing	_	_	_	_
49	virus	_	NOUN	_	Number=Sing	_	_	_	_
50	(	_	PUNCT	_	_	_	_	_	_
51	MMTV	_	PROPN	_	Number=Sing	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	long	_	ADJ	_	Degree=Pos	_	_	_	_
54	terminal	_	NOUN	_	Number=Sing	_	_	_	_
55	repeat	_	NOUN	_	Number=Sing	_	_	_	_
56	(	_	PUNCT	_	_	_	_	_	_
57	LTR	_	PROPN	_	Number=Sing	_	_	_	_
58	)	_	PUNCT	_	_	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	interference	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	as	_	SCONJ	_	_	_	_	_	_
12	TPA	_	PROPN	_	Number=Sing	_	_	_	_
13	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	MMTV	_	PROPN	_	Number=Sing	_	_	_	_
22	LTR	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	several	_	ADJ	_	Degree=Pos	_	_	_	_
25	T	_	NOUN	_	NumType=Card	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	lines	_	NOUN	_	Number=Plur	_	_	_	_
28	but	_	CCONJ	_	_	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	inhibitory	_	ADJ	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	NIH	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	3T3	_	NOUN	_	Number=Sing	_	_	_	_
35	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	TPA	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	GR	_	NOUN	_	Number=Sing	_	_	_	_
4	synergism	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	determined	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	have	_	AUX	_	VerbForm=Inf	_	_	_	_
9	occurred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	GR	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
15	element	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	GRE	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	level	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	functional	_	ADJ	_	Degree=Pos	_	_	_	_
22	analysis	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	deletion	_	NOUN	_	Number=Sing	_	_	_	_
25	mutants	_	NOUN	_	Number=Plur	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
28	GRE	_	NOUN	_	Number=Sing	_	_	_	_
29	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
30	driving	_	VERB	_	VerbForm=Ger	_	_	_	_
31	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
32	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	transferase	_	NOUN	_	Number=Sing	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Synergism	_	PROPN	_	Number=Sing	_	_	_	_
2	required	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	intact	_	NOUN	_	Degree=Pos	_	_	_	_
5	GR	_	NOUN	_	Number=Sing	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	domain	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	whereas	_	SCONJ	_	_	_	_	_	_
12	amino	_	ADJ	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	carboxyl	_	ADJ	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
18	domains	_	NOUN	_	Number=Plur	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	dispensable	_	ADJ	_	Degree=Pos	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	abrogated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	PKC	_	PROPN	_	Number=Sing	_	_	_	_
8	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
9	staurosporine	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	PKC	_	PROPN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	jun-B	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	jun	_	NOUN	_	Number=Sing	_	_	_	_
8	-D	_	PUNCT	_	_	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	above	_	ADP	_	_	_	_	_	_
11	basal	_	ADJ	_	Degree=Pos	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1/TPA	_	NUM	_	Number=Sing	_	_	_	_
21	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
22	elements	_	NOUN	_	Number=Plur	_	_	_	_
23	fused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
26	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	transferase	_	NOUN	_	Number=Sing	_	_	_	_
29	vectors	_	NOUN	_	Number=Plur	_	_	_	_
30	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	T	_	PROPN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	TPA	_	PROPN	_	Number=Sing	_	_	_	_
38	alone	_	ADJ	_	_	_	_	_	_
39	or	_	CCONJ	_	_	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	combination	_	NOUN	_	Number=Sing	_	_	_	_
42	with	_	ADP	_	_	_	_	_	_
43	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Jun	_	PROPN	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	cooperate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	GR	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
15	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	after	_	ADP	_	_	_	_	_	_
17	transfection	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	jun-B	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	jun	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	D	_	NOUN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	vectors	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	which	_	PRON	_	PronType=Rel	_	_	_	_
31	augmented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	GR	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	from	_	ADP	_	_	_	_	_	_
37	either	_	CCONJ	_	_	_	_	_	_
38	MMTV	_	PROPN	_	Number=Sing	_	_	_	_
39	LTR	_	NOUN	_	Number=Sing	_	_	_	_
40	or	_	CCONJ	_	_	_	_	_	_
41	GRE	_	PROPN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Conversely	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	c	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	jun	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	jun	_	NOUN	_	Number=Sing	_	_	_	_
8	-B	_	NOUN	_	_	_	_	_	_
9	transfection	_	NOUN	_	Number=Sing	_	_	_	_
10	blunted	_	VERB	_	Degree=Pos	_	_	_	_
11	GR	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	presence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	fos	_	PROPN	_	Number=Sing	_	_	_	_
7	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	negative	_	ADJ	_	Degree=Pos	_	_	_	_
10	influence	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	GR	_	NOUN	_	Number=Sing	_	_	_	_
13	function	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	synergistic	_	ADJ	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	antagonistic	_	ADJ	_	Degree=Pos	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	Jun	_	PROPN	_	Number=Sing	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	respect	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	GR	_	NOUN	_	Number=Sing	_	_	_	_
31	;	_	PUNCT	_	_	_	_	_	_
32	high	_	ADJ	_	Degree=Pos	_	_	_	_
33	basal	_	ADJ	_	Degree=Pos	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	c	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	fos	_	NOUN	_	Number=Sing	_	_	_	_
39	as	_	ADV	_	_	_	_	_	_
40	well	_	ADV	_	Degree=Pos	_	_	_	_
41	as	_	ADP	_	_	_	_	_	_
42	AP	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	DNA	_	PROPN	_	Number=Sing	_	_	_	_
46	binding	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
49	activity	_	NOUN	_	Number=Sing	_	_	_	_
50	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
51	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
54	cells	_	NOUN	_	Number=Plur	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	but	_	CCONJ	_	_	_	_	_	_
57	not	_	ADV	_	_	_	_	_	_
58	in	_	ADP	_	_	_	_	_	_
59	T	_	PROPN	_	Number=Sing	_	_	_	_
60	cells	_	NOUN	_	Number=Plur	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
5	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
6	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	GR	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	GRE	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	Jun	_	PROPN	_	Number=Sing	_	_	_	_
5	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	bifunctional	_	ADJ	_	Degree=Pos	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	GR	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	GRE	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	selecting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	either	_	CCONJ	_	_	_	_	_	_
20	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	antagonistic	_	ADJ	_	Degree=Pos	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	depending	_	VERB	_	VerbForm=Ger	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	specific	_	ADJ	_	Degree=Pos	_	_	_	_
30	microenvironment	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	regard	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	fos	_	NOUN	_	Number=Sing	_	_	_	_
11	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	influential	_	ADJ	_	Degree=Pos	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002357	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cupric	_	NOUN	_	Number=Sing	_	_	_	_
2	ion	_	NOUN	_	Number=Sing	_	_	_	_
3	blocks	_	NOUN	_	Number=Plur	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	through	_	SCONJ	_	_	_	_	_	_
9	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	signal	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	kappa	_	VERB	_	Number=Sing	_	_	_	_
18	B	_	PROPN	_	Number=Sing	_	_	_	_
19	alpha	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	various	_	ADJ	_	Degree=Pos	_	_	_	_
13	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	involved	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	immune	_	ADJ	_	Degree=Pos	_	_	_	_
18	responses	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	viral	_	ADJ	_	Degree=Pos	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	including	_	VERB	_	VerbForm=Ger	_	_	_	_
23	HIV	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	sequestered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	complex	_	NOUN	_	Number=Sing	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
36	protein	_	NOUN	_	Number=Sing	_	_	_	_
37	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
38	kappa	_	VERB	_	Number=Sing	_	_	_	_
39	B.	_	PROPN	_	Number=Sing	_	_	_	_
40	Various	_	ADJ	_	Degree=Pos	_	_	_	_
41	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
42	signals	_	NOUN	_	Number=Plur	_	_	_	_
43	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
44	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
47	degradation	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
50	kappa	_	VERB	_	Number=Sing	_	_	_	_
51	B	_	PROPN	_	Number=Sing	_	_	_	_
52	alpha	_	NOUN	_	Number=Sing	_	_	_	_
53	to	_	PART	_	_	_	_	_	_
54	release	_	VERB	_	VerbForm=Inf	_	_	_	_
55	NF	_	PROPN	_	Number=Sing	_	_	_	_
56	kappa	_	PROPN	_	Number=Sing	_	_	_	_
57	B.	_	PROPN	_	Number=Sing	_	_	_	_
58	Cu2	_	PROPN	_	Number=Sing	_	_	_	_
59	+	_	SYM	_	_	_	_	_	_
60	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
61	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
62	to	_	PART	_	_	_	_	_	_
63	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
64	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
65	activation	_	NOUN	_	Number=Sing	_	_	_	_
66	of	_	ADP	_	_	_	_	_	_
67	NF	_	PROPN	_	Number=Sing	_	_	_	_
68	kappa	_	PROPN	_	Number=Sing	_	_	_	_
69	B	_	NOUN	_	Number=Sing	_	_	_	_
70	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
71	by	_	ADP	_	_	_	_	_	_
72	TNF	_	PROPN	_	Number=Sing	_	_	_	_
73	-	_	PUNCT	_	_	_	_	_	_
74	alpha	_	NOUN	_	Number=Sing	_	_	_	_
75	,	_	PUNCT	_	_	_	_	_	_
76	TPA	_	PROPN	_	Number=Sing	_	_	_	_
77	,	_	PUNCT	_	_	_	_	_	_
78	or	_	CCONJ	_	_	_	_	_	_
79	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
80	.	_	PUNCT	_	_	_	_	_	_

1	Deoxycholate	_	ADJ	_	Degree=Pos	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
6	extract	_	NOUN	_	Number=Sing	_	_	_	_
7	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	presence	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	Cu2	_	PROPN	_	Number=Sing	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_
21	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	release	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
31	kappa	_	VERB	_	Number=Sing	_	_	_	_
32	B	_	PROPN	_	Number=Sing	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
36	that	_	SCONJ	_	_	_	_	_	_
37	Cu2	_	PROPN	_	Number=Sing	_	_	_	_
38	+	_	SYM	_	_	_	_	_	_
39	interferes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	NF	_	PROPN	_	Number=Sing	_	_	_	_
46	kappa	_	NOUN	_	Number=Sing	_	_	_	_
47	B	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
50	kappa	_	VERB	_	Number=Sing	_	_	_	_
51	B	_	PROPN	_	Number=Sing	_	_	_	_
52	complex	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Neither	_	CCONJ	_	_	_	_	_	_
2	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
3	nor	_	CCONJ	_	_	_	_	_	_
4	degradation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	kappa	_	PROPN	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	upon	_	ADP	_	_	_	_	_	_
13	TNF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	presence	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	Cu2	_	NOUN	_	Number=Sing	_	_	_	_
22	+	_	SYM	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Cu2	_	PROPN	_	Number=Sing	_	_	_	_
6	+	_	SYM	_	_	_	_	_	_
7	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	release	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	blockade	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	signal	_	NOUN	_	Number=Sing	_	_	_	_
19	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	kappa	_	VERB	_	Number=Sing	_	_	_	_
26	B	_	PROPN	_	Number=Sing	_	_	_	_
27	alpha	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002358	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Vitamin	_	PROPN	_	Number=Sing	_	_	_	_
2	D3	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
6	acid	_	ADJ	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	interactions	_	NOUN	_	Number=Plur	_	_	_	_
13	between	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
16	vitamin	_	NOUN	_	Number=Sing	_	_	_	_

1	D3	_	VERB	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	retinoic	_	ADJ	_	Number=Sing	_	_	_	_
5	acid	_	NOUN	_	Number=Sing	_	_	_	_
6	receptors	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	retinoid	_	VERB	_	Number=Sing	_	_	_	_
10	X	_	SYM	_	_	_	_	_	_
11	receptors	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	U	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	937	_	NUM	_	NumType=Card	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Retinoic	_	PROPN	_	Number=Sing	_	_	_	_
2	acid	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	RA	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	1,25	_	NUM	_	NumType=Card	_	_	_	_
8	alpha-dihydroxycholecalciferol	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	potent	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulators	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	hematopoletic	_	ADJ	_	Degree=Pos	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Yet	_	CCONJ	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	little	_	ADV	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	to	_	SCONJ	_	_	_	_	_	_
8	how	_	ADV	_	PronType=Int	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	RA	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	VitD3	_	PROPN	_	Number=Sing	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	network	_	NOUN	_	Number=Sing	_	_	_	_
15	operates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	whether	_	SCONJ	_	_	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	interactions	_	NOUN	_	Number=Plur	_	_	_	_
24	can	_	AUX	_	VerbForm=Fin	_	_	_	_
25	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	interplay	_	NOUN	_	Number=Sing	_	_	_	_
28	between	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	RA	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
36	pathways	_	NOUN	_	Number=Plur	_	_	_	_
37	during	_	ADP	_	_	_	_	_	_
38	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	DNA	_	PROPN	_	Number=Sing	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
17	RA	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
20	receptors	_	NOUN	_	Number=Plur	_	_	_	_
21	[	_	PUNCT	_	_	_	_	_	_
22	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
23	acid	_	NOUN	_	Number=Sing	_	_	_	_
24	receptors	_	NOUN	_	Number=Plur	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	RARs	_	NOUN	_	Number=Plur	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
30	X	_	SYM	_	_	_	_	_	_
31	receptors	_	NOUN	_	Number=Plur	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	RXRs	_	NOUN	_	Number=Plur	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
38	receptor	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	VDR	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	]	_	PUNCT	_	_	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	U	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	937	_	NUM	_	NumType=Card	_	_	_	_
48	cell	_	NOUN	_	Number=Sing	_	_	_	_
49	line	_	NOUN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	in	_	ADP	_	_	_	_	_	_
52	which	_	PRON	_	PronType=Rel	_	_	_	_
53	RA	_	NOUN	_	Number=Sing	_	_	_	_
54	and	_	CCONJ	_	_	_	_	_	_
55	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
56	induce	_	VERB	_	_	_	_	_	_
57	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
58	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
59	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
60	pathways	_	NOUN	_	Number=Plur	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	formation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	VDR	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	RXR	_	PROPN	_	Number=Sing	_	_	_	_
11	DNA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	complexes	_	NOUN	_	Number=Plur	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	both	_	CCONJ	_	_	_	_	_	_
17	VitD3	_	VERB	_	Degree=Pos	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	elements	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	RA	_	NOUN	_	Number=Sing	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	elements	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	RAREs	_	NOUN	_	Number=Plur	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	only	_	ADV	_	_	_	_	_	_
7	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	VitD3	_	VERB	_	Number=Sing	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	reporter	_	NOUN	_	Number=Sing	_	_	_	_
16	construct	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	DNA	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	complexes	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	RAREs	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	undifferentiated	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	RA	_	PROPN	_	Number=Sing	_	_	_	_
4	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	RAR	_	NOUN	_	Number=Sing	_	_	_	_
8	beta	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	RXR	_	PROPN	_	Number=Sing	_	_	_	_
11	DNA	_	NOUN	_	Number=Sing	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	RARE	_	ADJ	_	Degree=Pos	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	RAR	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	beta	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	VitD3	_	PROPN	_	Number=Sing	_	_	_	_
5	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	RA	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	formation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	RAR	_	PROPN	_	Number=Sing	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	RXR	_	PROPN	_	Number=Sing	_	_	_	_
16	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	favoring	_	VERB	_	VerbForm=Ger	_	_	_	_
19	VDR	_	PROPN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	RXR	_	PROPN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	RARE	_	ADJ	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Also	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	VitD3	_	PROPN	_	Number=Sing	_	_	_	_
4	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	CD23	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	CD49f	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	characteristic	_	ADJ	_	Degree=Pos	_	_	_	_
13	markers	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	U	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	937	_	NUM	_	NumType=Card	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	neither	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	RA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	RARE	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	nor	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	RAR	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	VitD3	_	PROPN	_	Number=Sing	_	_	_	_
29	selectively	_	ADV	_	_	_	_	_	_
30	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
36	program	_	NOUN	_	Number=Sing	_	_	_	_
37	but	_	CCONJ	_	_	_	_	_	_
38	not	_	ADV	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	RARE	_	ADJ	_	Degree=Pos	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
43	signal	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	complex	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	SCONJ	_	_	_	_	_	_
10	modifying	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	retinoid	_	ADJ	_	Degree=Pos	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	pathway	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	have	_	VERB	_	VerbForm=Inf	_	_	_	_
18	implications	_	NOUN	_	Number=Plur	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	therapy	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
26	tumors	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002360	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Effects	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	production	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	stress	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	kinases	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	murine	_	NOUN	_	Number=Sing	_	_	_	_
29	T	_	NOUN	_	Number=Sing	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	line	_	NOUN	_	Number=Sing	_	_	_	_
32	EL4	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	association	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	kinase	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	IRAK	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	complex	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	one	_	NUM	_	NumType=Card	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	earliest	_	ADJ	_	Degree=Sup	_	_	_	_
30	events	_	NOUN	_	Number=Plur	_	_	_	_
31	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	signal	_	NOUN	_	Number=Sing	_	_	_	_
37	transduction	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	generated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	permanent	_	ADJ	_	Degree=Pos	_	_	_	_
4	clones	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	murine	_	NOUN	_	Number=Sing	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	EL4	_	PROPN	_	Number=Sing	_	_	_	_
12	6.1	_	NUM	_	NumType=Card	_	_	_	_
13	overexpressing	_	ADJ	_	VerbForm=Ger	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	h	_	X	_	_	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	IRAK	_	PROPN	_	Number=Sing	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	evaluate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	kinase	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	signaling	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	hIRAK	_	PROPN	_	Number=Sing	_	_	_	_
4	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	whereas	_	SCONJ	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	form	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	N	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	IRAK	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	specifically	_	ADV	_	_	_	_	_	_
27	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
33	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
34	activity	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	clones	_	NOUN	_	Number=Plur	_	_	_	_
3	stably	_	ADV	_	_	_	_	_	_
4	overexpressing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	hIRAK	_	PROPN	_	Number=Sing	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	weak	_	ADJ	_	Degree=Pos	_	_	_	_
8	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
12	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	low	_	ADJ	_	Degree=Pos	_	_	_	_
16	basal	_	ADJ	_	Degree=Pos	_	_	_	_
17	IL	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	production	_	NOUN	_	Number=Sing	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
31	manner	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	parental	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	line	_	NOUN	_	Number=Sing	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	dose	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	curve	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	production	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	shifted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	both	_	CCONJ	_	_	_	_	_	_
26	potency	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	efficacy	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IRAK	_	PROPN	_	Number=Sing	_	_	_	_
6	directly	_	ADV	_	_	_	_	_	_
7	triggers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	VERB	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	EL4	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Qualitatively	_	ADV	_	_	_	_	_	_
2	different	_	ADJ	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	stress	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	SAP	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	kinases	_	NOUN	_	Number=Plur	_	_	_	_
23	:	_	PUNCT	_	_	_	_	_	_
24	permanent	_	ADJ	_	Degree=Pos	_	_	_	_
25	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	IRAK	_	PROPN	_	Number=Sing	_	_	_	_
28	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	not	_	PART	_	_	_	_	_	_
30	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	dose	_	NOUN	_	Number=Sing	_	_	_	_
33	dependence	_	NOUN	_	Number=Sing	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	prolonged	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	activation	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	SAP	_	NOUN	_	Number=Sing	_	_	_	_
47	kinases	_	NOUN	_	Number=Plur	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
50	that	_	SCONJ	_	_	_	_	_	_
51	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
52	signaling	_	NOUN	_	Number=Sing	_	_	_	_
53	branch	_	NOUN	_	Number=Sing	_	_	_	_
54	may	_	AUX	_	VerbForm=Fin	_	_	_	_
55	be	_	AUX	_	VerbForm=Inf	_	_	_	_
56	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
57	by	_	ADP	_	_	_	_	_	_
58	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
59	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002362	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	p105	_	NOUN	_	Number=Sing	_	_	_	_
4	processing	_	VERB	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	transiently	_	ADV	_	_	_	_	_	_
12	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	processing	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB1	_	NOUN	_	Number=Sing	_	_	_	_
19	p105	_	NOUN	_	Number=Sing	_	_	_	_
20	precursor	_	NOUN	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	generates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	p50	_	NUM	_	Number=Sing	_	_	_	_
27	subunit	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	processing	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p105	_	NOUN	_	Number=Sing	_	_	_	_
5	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	constitutively	_	ADV	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	vivo	_	NOUN	_	Number=Sing	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	markedly	_	ADV	_	_	_	_	_	_
13	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	various	_	ADJ	_	Degree=Pos	_	_	_	_
16	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	agents	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	although	_	SCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	underlying	_	ADJ	_	Degree=Pos	_	_	_	_
23	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	yet	_	ADV	_	_	_	_	_	_
28	clear	_	ADJ	_	Degree=Pos	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	DET	_	_	_	_	_	_
9	signal	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	p105	_	NOUN	_	Number=Sing	_	_	_	_
15	processing	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	de	_	X	_	Number=Sing	_	_	_	_
24	novo	_	X	_	Number=Sing	_	_	_	_
25	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	precursor	_	NOUN	_	Number=Sing	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	performed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	COS7	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	newly	_	ADV	_	_	_	_	_	_
12	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	p105	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	more	_	ADV	_	_	_	_	_	_
19	rapidly	_	ADV	_	_	_	_	_	_
20	processed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	accumulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	form	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	already	_	ADV	_	_	_	_	_	_
29	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	processed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	product	_	NOUN	_	Number=Sing	_	_	_	_
34	p50	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	processing	_	NOUN	_	Number=Sing	_	_	_	_
5	rate	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	p105	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	markedly	_	ADV	_	_	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	co	_	NOUN	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	p50	_	NUM	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	other	_	ADJ	_	Degree=Pos	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	subunits	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	including	_	VERB	_	VerbForm=Ger	_	_	_	_
26	RelA	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	that	_	PRON	_	PronType=Rel	_	_	_	_
31	physically	_	ADV	_	_	_	_	_	_
32	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	p105	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	processing	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	p105	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	subject	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	negative	_	ADJ	_	Degree=Pos	_	_	_	_
13	regulation	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	various	_	ADJ	_	Degree=Pos	_	_	_	_
17	NF	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	subunits	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	p105	_	NOUN	_	Number=Sing	_	_	_	_
6	undergoes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	degradation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
5	degradation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	p105	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	coupled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	generation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	p50	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	processing	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
11	degradation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	p105	_	NOUN	_	Number=Sing	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	differentially	_	ADV	_	_	_	_	_	_
16	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002363	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	jun	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	fos	_	ADP	_	_	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	family	_	NOUN	_	Number=Sing	_	_	_	_
9	members	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	13	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	acetate	_	NOUN	_	Number=Sing	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	hemopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Terminal	_	ADJ	_	Number=Sing	_	_	_	_
2	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	lines	_	NOUN	_	Number=Plur	_	_	_	_
8	U	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	937	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	HL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	60	_	NUM	_	NumType=Card	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	13	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	acetate	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	changes	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	jun	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	fos	_	ADP	_	_	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	family	_	NOUN	_	Number=Sing	_	_	_	_
16	members	_	NOUN	_	Number=Plur	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	variable	_	ADJ	_	Degree=Pos	_	_	_	_
21	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
22	during	_	ADP	_	_	_	_	_	_
23	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	13	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	acetate	_	NOUN	_	Number=Sing	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	c	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	jun	_	NOUN	_	Number=Sing	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	best	_	ADJ	_	Degree=Sup	_	_	_	_
37	paralleling	_	NOUN	_	VerbForm=Ger	_	_	_	_
38	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	generation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	complexes	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	as	_	SCONJ	_	_	_	_	_	_
10	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	DNA	_	NOUN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	closely	_	ADV	_	_	_	_	_	_
17	parallels	_	VERB	_	_	_	_	_	_
18	morphological	_	ADJ	_	Degree=Pos	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	ability	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	complexes	_	NOUN	_	Number=Plur	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	AP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	reporter	_	NOUN	_	Number=Sing	_	_	_	_
24	construct	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	increases	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
33	AP	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	regulated	_	VERB	_	Degree=Pos	_	_	_	_
37	genes	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Differentiation	_	NOUN	_	Number=Sing	_	_	_	_
2	assays	_	NOUN	_	Number=Plur	_	_	_	_
3	using	_	VERB	_	VerbForm=Ger	_	_	_	_
4	water	_	NOUN	_	Number=Sing	_	_	_	_
5	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
6	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
7	esters	_	NOUN	_	Number=Plur	_	_	_	_
8	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	becomes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	irreversible	_	ADJ	_	Degree=Pos	_	_	_	_
13	soon	_	ADV	_	Degree=Pos	_	_	_	_
14	after	_	ADP	_	_	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	tight	_	ADJ	_	Degree=Pos	_	_	_	_
3	correlation	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	c	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	jun	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	generation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	critical	_	ADJ	_	Degree=Pos	_	_	_	_
23	role	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	complex	_	NOUN	_	Number=Sing	_	_	_	_
30	during	_	ADP	_	_	_	_	_	_
31	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
32	process	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002364	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
2	initiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	Rac	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	but	_	CCONJ	_	_	_	_	_	_
7	not	_	ADV	_	_	_	_	_	_
8	phosphatidyl	_	ADJ	_	Number=Sing	_	_	_	_
9	inositol	_	NOUN	_	Number=Sing	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	PKB	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	mediated	_	VERB	_	Degree=Pos	_	_	_	_
16	signaling	_	NOUN	_	Number=Sing	_	_	_	_
17	pathways	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	antigen	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	TCR	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	then	_	ADV	_	PronType=Dem	_	_	_	_
15	co-ordinates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	important	_	ADJ	_	Degree=Pos	_	_	_	_
17	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
18	pathways	_	NOUN	_	Number=Plur	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Effector	_	NOUN	_	Number=Sing	_	_	_	_
2	pathways	_	NOUN	_	Number=Plur	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	guanine	_	NOUN	_	Degree=Pos	_	_	_	_
6	nucleotide	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	serine	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	threonine	_	NOUN	_	Number=Sing	_	_	_	_
19	kinase	_	NOUN	_	Number=Sing	_	_	_	_
20	Raf	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	Ras	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	related	_	ADJ	_	Degree=Pos	_	_	_	_
28	GTPase	_	NOUN	_	Number=Sing	_	_	_	_
29	Rac	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	effector	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Ras	_	PROPN	_	Number=Sing	_	_	_	_
10	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	Phosphatidylinositol	_	PROPN	_	Number=Sing	_	_	_	_
13	3	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	PtdIns	_	NOUN	_	Number=Sing	_	_	_	_
18	3	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	lipid	_	ADJ	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	able	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
10	critical	_	ADJ	_	Degree=Pos	_	_	_	_
11	Rac	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	signaling	_	NOUN	_	Number=Sing	_	_	_	_
15	pathways	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	can	_	AUX	_	VerbForm=Fin	_	_	_	_
18	couple	_	NOUN	_	VerbForm=Inf	_	_	_	_
19	p21ras	_	NOUN	_	Number=Plur	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	cell	_	VERB	_	VerbForm=Inf	_	_	_	_
22	survival	_	NOUN	_	Number=Sing	_	_	_	_
23	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
24	via	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	serine	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	threonine	_	NOUN	_	Number=Sing	_	_	_	_
29	kinase	_	NOUN	_	Number=Sing	_	_	_	_
30	Akt	_	PROPN	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	PKB	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	PtdIns	_	PROPN	_	Number=Sing	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	Ras	_	PROPN	_	Number=Sing	_	_	_	_
10	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	explored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	ability	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	PtdIns	_	NOUN	_	Number=Sing	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kinase	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	Rac	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	signaling	_	NOUN	_	Number=Sing	_	_	_	_
22	pathways	_	NOUN	_	Number=Plur	_	_	_	_
23	important	_	ADJ	_	Degree=Pos	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	T	_	NUM	_	NumType=Card	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	possibility	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	Akt	_	PROPN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	PKB	_	PROPN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	Ras	_	PROPN	_	Number=Sing	_	_	_	_
14	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
15	pathways	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Ras	_	PROPN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	Rac	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
13	pathway	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	function	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	complexes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	PtdIns	_	PROPN	_	Number=Sing	_	_	_	_
2	3	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_
5	signals	_	NOUN	_	Number=Plur	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	mimic	_	VERB	_	VerbForm=Inf	_	_	_	_
9	p21ras	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	Rac	_	PROPN	_	Number=Sing	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	responses	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	AP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	neither	_	CCONJ	_	_	_	_	_	_
4	TCR	_	NOUN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	Ras	_	PROPN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	PtdIns	_	NOUN	_	Number=Sing	_	_	_	_
16	3-	_	NUM	_	NumType=Card	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	PKB	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	response	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	triggering	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	antigen	_	NOUN	_	Number=Sing	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	;	_	PUNCT	_	_	_	_	_	_
15	PtdIns	_	NOUN	_	Number=Sing	_	_	_	_
16	3	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kinase	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	both	_	CCONJ	_	_	_	_	_	_
22	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
27	TCR	_	NOUN	_	Number=Sing	_	_	_	_
28	response	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
5	signals	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	unable	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
10	Akt	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	PKB	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	nor	_	CCONJ	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	Ras	_	PROPN	_	Number=Sing	_	_	_	_
20	function	_	NOUN	_	Number=Sing	_	_	_	_
21	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	Akt	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	PKB	_	PROPN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	response	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	TCR	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	data	_	NOUN	_	Number=Sing	_	_	_	_
4	thus	_	ADV	_	_	_	_	_	_
5	highlight	_	VERB	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	PtdIns	_	PROPN	_	Number=Sing	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kinase	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Akt	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	PKB	_	PROPN	_	Number=Sing	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	universal	_	ADJ	_	Degree=Pos	_	_	_	_
18	Ras	_	NOUN	_	Number=Sing	_	_	_	_
19	effector	_	NOUN	_	Number=Sing	_	_	_	_
20	molecules	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Ras	_	PROPN	_	Number=Sing	_	_	_	_
2	can	_	AUX	_	VerbForm=Fin	_	_	_	_
3	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
4	Rac	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	regulated	_	VERB	_	Degree=Pos	_	_	_	_
8	signaling	_	NOUN	_	Number=Sing	_	_	_	_
9	pathways	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	context	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	antigen	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	function	_	NOUN	_	Number=Sing	_	_	_	_
19	independently	_	ADV	_	_	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	PtdIns	_	PROPN	_	Number=Sing	_	_	_	_
22	3	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kinase	_	NOUN	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002368	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Calcineurin	_	PROPN	_	Number=Sing	_	_	_	_
2	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	GM	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	CSF	_	NOUN	_	Number=Sing	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	synergy	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	either	_	CCONJ	_	_	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	C	_	PROPN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	AP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	T	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	cis	_	NOUN	_	Number=Plur	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	acting	_	VERB	_	Number=Sing	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	GM	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B/GC	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	box	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	CLE0	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
20	colony	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	GM	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	CSF	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
34	induction	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
37	T	_	PROPN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
41	with	_	ADP	_	_	_	_	_	_
42	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	12	_	NUM	_	NumType=Card	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	myristate	_	NOUN	_	Number=Sing	_	_	_	_
47	acetate	_	NOUN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	PMA	_	PROPN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
53	+	_	SYM	_	_	_	_	_	_
54	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
55	(	_	PUNCT	_	_	_	_	_	_
56	A23187	_	NOUN	_	Number=Sing	_	_	_	_
57	)	_	PUNCT	_	_	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GM	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	PROPN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	mainly	_	ADV	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	PMA	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CLE0	_	PROPN	_	Number=Sing	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	related	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	PMA	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	PMA	_	PROPN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	A23187	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	AT	_	NOUN	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	signal	_	NOUN	_	Number=Sing	_	_	_	_
5	transducing	_	NOUN	_	Number=Sing	_	_	_	_
6	components	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	GM	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	CSF	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	AP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	c-Jun/c-Fos	_	NOUN	_	Number=Sing	_	_	_	_
17	)-	_	PUNCT	_	_	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	vectors	_	NOUN	_	Number=Plur	_	_	_	_
20	into	_	ADP	_	_	_	_	_	_
21	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
26	reporter	_	NOUN	_	Number=Sing	_	_	_	_
27	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	GM	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	CSF	_	PROPN	_	Number=Sing	_	_	_	_
32	promoter	_	NOUN	_	Number=Sing	_	_	_	_
33	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
36	transcription	_	NOUN	_	Number=Sing	_	_	_	_
37	from	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	GM	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	CSF	_	NOUN	_	Number=Sing	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	combination	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	significantly	_	ADV	_	_	_	_	_	_
18	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	GM	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	CSF	_	NOUN	_	Number=Sing	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	GM	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B/GC	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	box	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	CLE0	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	AP	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1/NF	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	AT	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	constitutively	_	ADV	_	_	_	_	_	_
5	active	_	ADJ	_	Degree=Pos	_	_	_	_
6	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	CN	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	Ca2+/	_	NOUN	_	Number=Sing	_	_	_	_
13	calmodulin-dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	potentiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	two	_	NUM	_	NumType=Card	_	_	_	_
20	fold	_	NOUN	_	Number=Sing	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	AP	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	constitutively	_	ADV	_	_	_	_	_	_
3	active	_	ADJ	_	Degree=Pos	_	_	_	_
4	forms	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CN	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	protein	_	PROPN	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	C	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	PKC	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	synergistically	_	ADV	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	GM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	CSF	_	NOUN	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
6	among	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	AP	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	AT	_	ADP	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	sequences	_	NOUN	_	Number=Plur	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	induction	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	GM	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	CSF	_	PROPN	_	Number=Sing	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	through	_	ADP	_	_	_	_	_	_
35	PKC	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
39	+-	_	PUNCT	_	_	_	_	_	_
40	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
41	pathways	_	NOUN	_	Number=Plur	_	_	_	_
42	downstream	_	ADV	_	Degree=Pos	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	T	_	NOUN	_	Number=Sing	_	_	_	_
45	cell	_	NOUN	_	Number=Sing	_	_	_	_
46	activation	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002369	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nasal	_	PROPN	_	Number=Sing	_	_	_	_
2	NK	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
6	lymphomas	_	NOUN	_	Number=Plur	_	_	_	_
7	share	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	same	_	ADJ	_	Degree=Pos	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	Barr	_	PROPN	_	Number=Sing	_	_	_	_
15	virus	_	NOUN	_	Number=Sing	_	_	_	_
16	latency	_	NOUN	_	Number=Sing	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	nasopharyngeal	_	ADJ	_	Degree=Pos	_	_	_	_
19	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	Hodgkin	_	PROPN	_	Number=Sing	_	_	_	_
22	's	_	PART	_	_	_	_	_	_
23	disease	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Nasal	_	PROPN	_	Degree=Pos	_	_	_	_
2	T/NK	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	lymphomas	_	NOUN	_	Number=Plur	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	further	_	ADV	_	_	_	_	_	_
9	separated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	into	_	ADP	_	_	_	_	_	_
11	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	natural	_	ADJ	_	Degree=Pos	_	_	_	_
14	killer	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	NK	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lineage	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
23	lineage	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	differences	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
29	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
32	receptor	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	TcR	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	TcR	_	NOUN	_	Number=Sing	_	_	_	_
40	transcript	_	NOUN	_	Number=Sing	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	NK	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
6	subtypes	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	closely	_	ADV	_	_	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	Barr	_	PROPN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	EBV	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	EBV	_	PROPN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	23	_	NUM	_	NumType=Card	_	_	_	_
12	cases	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	nasal	_	ADJ	_	Degree=Pos	_	_	_	_
15	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	NL	_	X	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	situ	_	NOUN	_	Number=Sing	_	_	_	_
22	hybridisation	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	ISH	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	reverse	_	NOUN	_	Degree=Pos	_	_	_	_
28	transcriptase	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
31	chain	_	NOUN	_	Number=Sing	_	_	_	_
32	reaction	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	RT	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	PCR	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	immunohistochemistry	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	IH	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Of	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	23	_	NUM	_	NumType=Card	_	_	_	_
4	cases	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	19	_	NUM	_	NumType=Card	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	classified	_	ADJ	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	NK	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
17	tumours	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	ISH	_	PROPN	_	Number=Sing	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	EBV	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	small	_	ADJ	_	Degree=Pos	_	_	_	_
7	non-polyadenylated	_	ADJ	_	Degree=Pos	_	_	_	_
8	RNAs	_	PROPN	_	Number=Plur	_	_	_	_
9	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	all	_	DET	_	_	_	_	_	_
12	cases	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	whether	_	SCONJ	_	_	_	_	_	_
15	NK	_	PROPN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	harboured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	EBV	_	PROPN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	virtually	_	ADV	_	_	_	_	_	_
23	all	_	DET	_	_	_	_	_	_
24	tumour	_	ADJ	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	RT	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	PCR	_	PROPN	_	Number=Sing	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	NL	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	both	_	DET	_	_	_	_	_	_
9	subtypes	_	NOUN	_	Number=Plur	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	EBNAI	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	QUK	_	PROPN	_	Number=Sing	_	_	_	_
15	splice	_	NOUN	_	Number=Sing	_	_	_	_
16	pattern	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	latent	_	ADJ	_	Degree=Pos	_	_	_	_
20	membrane	_	NOUN	_	Number=Sing	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	BamHI	_	PROPN	_	Number=Sing	_	_	_	_
29	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	rightward	_	ADJ	_	Degree=Pos	_	_	_	_
31	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	absence	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	EBNA2	_	PROPN	_	Number=Sing	_	_	_	_
37	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	compatible	_	ADJ	_	Degree=Pos	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	latency	_	NOUN	_	Number=Sing	_	_	_	_
43	type	_	NOUN	_	Number=Sing	_	_	_	_
44	II	_	NUM	_	NumType=Card	_	_	_	_
45	pattern	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	EBV	_	PROPN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	IH	_	PROPN	_	Number=Sing	_	_	_	_
11	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	heterogeneous	_	ADJ	_	Degree=Pos	_	_	_	_
14	pattern	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	EBV	_	PROPN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	at	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	single	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	level	_	NOUN	_	Number=Sing	_	_	_	_
25	consisting	_	VERB	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	both	_	CCONJ	_	_	_	_	_	_
28	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
29	+	_	SYM	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	tumour	_	NOUN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	mixture	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	latency	_	NOUN	_	Number=Sing	_	_	_	_
41	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	II	_	NUM	_	NumType=Card	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	2	_	NUM	_	NumType=Card	_	_	_	_
3	early	_	ADJ	_	Degree=Pos	_	_	_	_
4	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
5	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	BZLF1	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	BHRF1	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	13	_	NUM	_	NumType=Card	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	10	_	NUM	_	NumType=Card	_	_	_	_
18	cases	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	respectively	_	ADV	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	lack	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
26	staining	_	VERB	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	any	_	DET	_	_	_	_	_	_
29	case	_	NOUN	_	Number=Sing	_	_	_	_
30	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
33	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
34	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
35	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	most	_	ADV	_	_	_	_	_	_
37	likely	_	ADV	_	_	_	_	_	_
38	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	rare	_	ADJ	_	Degree=Pos	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	biopsies	_	NOUN	_	Number=Plur	_	_	_	_
45	entering	_	VERB	_	VerbForm=Ger	_	_	_	_
46	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
47	cycle	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	viral	_	ADJ	_	Degree=Pos	_	_	_	_
3	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
4	pattern	_	NOUN	_	Number=Sing	_	_	_	_
5	similar	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	nasopharyngeal	_	ADJ	_	Degree=Pos	_	_	_	_
10	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Hodgkin	_	PROPN	_	Number=Sing	_	_	_	_
13	's	_	PART	_	_	_	_	_	_
14	disease	_	NOUN	_	Number=Sing	_	_	_	_
15	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	EBV	_	PROPN	_	Number=Sing	_	_	_	_
18	can	_	AUX	_	VerbForm=Fin	_	_	_	_
19	exploit	_	VERB	_	VerbForm=Inf	_	_	_	_
20	common	_	ADJ	_	Degree=Pos	_	_	_	_
21	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
28	host	_	NOUN	_	Number=Sing	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	types	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Down-regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	immunogenic	_	ADJ	_	Degree=Pos	_	_	_	_
4	proteins	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EBNA2	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	EBNA6	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	nasal	_	ADJ	_	Degree=Pos	_	_	_	_
12	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	enable	_	VERB	_	VerbForm=Inf	_	_	_	_
15	tumour	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	evade	_	VERB	_	VerbForm=Inf	_	_	_	_
19	host	_	ADJ	_	Number=Sing	_	_	_	_
20	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	surveillance	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002373	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CD40	_	NOUN	_	Number=Sing	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	immunogenic	_	ADJ	_	Degree=Pos	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
8	melanomas	_	NOUN	_	Number=Plur	_	_	_	_
9	augments	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	lysis	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	functional	_	ADJ	_	Degree=Pos	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	CD40	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
13	melanomas	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	MMs	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Comparison	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	tumor	_	NOUN	_	Number=Sing	_	_	_	_
4	specimen	_	NOUN	_	Number=Sing	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	MM	_	PROPN	_	Number=Sing	_	_	_	_
7	precursor	_	NOUN	_	Number=Sing	_	_	_	_
8	lesions	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	primary	_	ADJ	_	Degree=Pos	_	_	_	_
11	tumors	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	metastases	_	NOUN	_	Number=Plur	_	_	_	_
15	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	CD40	_	PROPN	_	Number=Sing	_	_	_	_
18	surface	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	down	_	ADV	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	regulated	_	VERB	_	Degree=Pos	_	_	_	_
24	during	_	ADP	_	_	_	_	_	_
25	tumor	_	NOUN	_	Number=Sing	_	_	_	_
26	progression	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	CD40	_	PROPN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	7	_	NUM	_	NumType=Card	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	MM	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	lines	_	NOUN	_	Number=Plur	_	_	_	_
11	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	immunogenic	_	ADJ	_	Degree=Pos	_	_	_	_
14	primary	_	ADJ	_	Degree=Pos	_	_	_	_
15	tumors	_	NOUN	_	Number=Plur	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	metastases	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	whereas	_	SCONJ	_	_	_	_	_	_
20	11	_	NUM	_	NumType=Card	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	lines	_	NOUN	_	Number=Plur	_	_	_	_
23	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	advanced	_	ADJ	_	Degree=Pos	_	_	_	_
26	stages	_	NOUN	_	Number=Plur	_	_	_	_
27	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	CD40	_	PROPN	_	Number=Sing	_	_	_	_
29	negative	_	NOUN	_	Degree=Pos	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	CD40	_	PROPN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	could	_	AUX	_	VerbForm=Fin	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	CD40	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	positive	_	ADJ	_	Degree=Pos	_	_	_	_
10	MM	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	IFN	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	gamma	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	tumor	_	NOUN	_	Number=Sing	_	_	_	_
19	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1beta	_	PROPN	_	Number=Sing	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	CD40	_	PROPN	_	Number=Sing	_	_	_	_
34	triggering	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	CD40	_	PROPN	_	Number=Sing	_	_	_	_
2	ligation	_	NOUN	_	Number=Sing	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	MM	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	CD40L	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	murine	_	NOUN	_	Number=Sing	_	_	_	_
10	L	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
17	CD40L	_	NOUN	_	Number=Sing	_	_	_	_
18	fusion	_	NOUN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	up	_	ADP	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
27	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
28	molecule	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	MHC	_	PROPN	_	Number=Sing	_	_	_	_
33	class	_	NOUN	_	Number=Sing	_	_	_	_
34	I	_	NOUN	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	class	_	NOUN	_	Number=Sing	_	_	_	_
37	II	_	NUM	_	NumType=Card	_	_	_	_
38	molecules	_	NOUN	_	Number=Plur	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
41	secretion	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	IL	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	6	_	NUM	_	NumType=Card	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	IL	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	8	_	NUM	_	NumType=Card	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	tumor	_	NOUN	_	Number=Sing	_	_	_	_
52	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
53	factor	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	a	_	NOUN	_	Number=Sing	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	and	_	CCONJ	_	_	_	_	_	_
58	granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
59	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
60	colony	_	NOUN	_	Number=Sing	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
63	factor	_	NOUN	_	Number=Sing	_	_	_	_
64	and	_	CCONJ	_	_	_	_	_	_
65	also	_	ADV	_	_	_	_	_	_
66	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
67	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
68	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
69	activation	_	NOUN	_	Number=Sing	_	_	_	_
70	of	_	ADP	_	_	_	_	_	_
71	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
72	transcription	_	NOUN	_	Number=Sing	_	_	_	_
73	factor	_	NOUN	_	Number=Sing	_	_	_	_
74	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
75	factor	_	NOUN	_	Number=Sing	_	_	_	_
76	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
77	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CD40	_	PROPN	_	Number=Sing	_	_	_	_
4	ligation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	HLA	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	A2	_	NOUN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	MelanA	_	PROPN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	MART1	_	PROPN	_	Number=Sing	_	_	_	_
15	+	_	SYM	_	_	_	_	_	_

1	MM	_	PROPN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	line	_	NOUN	_	Number=Sing	_	_	_	_
4	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
6	susceptibility	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	lysis	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	HLA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	A2	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	MelanA	_	PROPN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	MART	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1-specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	CTL	_	PROPN	_	Number=Sing	_	_	_	_
24	clone	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CD40	_	PROPN	_	Number=Sing	_	_	_	_
4	ligation	_	NOUN	_	Number=Sing	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	growth	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	MM	_	PROPN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CD40	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	CD40L	_	PROPN	_	Number=Sing	_	_	_	_
8	interactions	_	NOUN	_	Number=Plur	_	_	_	_
9	may	_	AUX	_	VerbForm=Fin	_	_	_	_
10	play	_	VERB	_	VerbForm=Inf	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	important	_	ADJ	_	Degree=Pos	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	SCONJ	_	_	_	_	_	_
15	augmenting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	antitumor	_	NOUN	_	Number=Sing	_	_	_	_
17	immunity	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	some	_	DET	_	_	_	_	_	_
23	CD40	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	positive	_	ADJ	_	Degree=Pos	_	_	_	_
26	immunogenic	_	ADJ	_	Degree=Pos	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	MMs	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002382	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Involvement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	adenylate	_	NOUN	_	Number=Sing	_	_	_	_
4	cyclase	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	p70	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	S6	_	NUM	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	10	_	NUM	_	NumType=Card	_	_	_	_
17	up	_	ADP	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	gp41	_	NOUN	_	Number=Sing	_	_	_	_
25	envelope	_	NOUN	_	Number=Sing	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
30	virus	_	NOUN	_	Number=Sing	_	_	_	_
31	type	_	NOUN	_	Number=Sing	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	previous	_	ADJ	_	Degree=Pos	_	_	_	_
3	results	_	NOUN	_	Number=Plur	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
7	gp41	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	aa565-647	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
14	domain	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	transmembrane	_	NOUN	_	Number=Sing	_	_	_	_
20	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	10	_	NUM	_	NumType=Card	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	10	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	production	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	human	_	ADJ	_	Degree=Pos	_	_	_	_
34	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	signal	_	NOUN	_	Number=Sing	_	_	_	_
3	cascade	_	NOUN	_	Number=Sing	_	_	_	_
4	transducing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	yet	_	ADV	_	_	_	_	_	_
10	clear	_	ADJ	_	Degree=Pos	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	whether	_	SCONJ	_	_	_	_	_	_
8	gp41	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	10	_	NUM	_	NumType=Card	_	_	_	_
14	up	_	ADP	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	previously	_	ADV	_	_	_	_	_	_
22	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	pathways	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	gp41	_	NOUN	_	Number=Sing	_	_	_	_
2	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
4	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	time	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	concentration	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	manner	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	adenylate	_	NOUN	_	Number=Sing	_	_	_	_
19	cyclase	_	NOUN	_	Number=Sing	_	_	_	_
20	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
21	SQ	_	NOUN	_	Number=Sing	_	_	_	_
22	22536	_	NUM	_	NumType=Card	_	_	_	_
23	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	gp41	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	10	_	NUM	_	NumType=Card	_	_	_	_
30	production	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	gp41	_	NOUN	_	Number=Sing	_	_	_	_
5	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	as	_	ADV	_	_	_	_	_	_
15	much	_	ADJ	_	Degree=Pos	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	no	_	DET	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	bound	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	main	_	ADJ	_	Degree=Pos	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	site	_	NOUN	_	Number=Sing	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	10	_	NUM	_	NumType=Card	_	_	_	_
37	promoter	_	NOUN	_	Number=Sing	_	_	_	_
38	after	_	ADP	_	_	_	_	_	_
39	addition	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	gp41	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	involvement	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	other	_	ADJ	_	Degree=Pos	_	_	_	_
8	signal	_	NOUN	_	Number=Sing	_	_	_	_
9	transduction	_	NOUN	_	Number=Sing	_	_	_	_
10	pathways	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Specific	_	ADJ	_	Degree=Pos	_	_	_	_
2	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p70	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	S6	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	Gi	_	PROPN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	pertussis	_	NOUN	_	Number=Sing	_	_	_	_
19	toxin	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	prevented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	induction	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	10	_	NUM	_	NumType=Card	_	_	_	_
28	production	_	NOUN	_	Number=Sing	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	gp41	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	while	_	SCONJ	_	_	_	_	_	_
35	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	phosphatidylinositol	_	NOUN	_	Number=Sing	_	_	_	_
39	3-	_	NUM	_	NumType=Card	_	_	_	_
40	kinase	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	PI	_	NOUN	_	Number=Sing	_	_	_	_
43	3	_	NUM	_	NumType=Card	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kinase	_	NOUN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	wortmannin	_	ADJ	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
54	protein	_	NOUN	_	Number=Sing	_	_	_	_
55	kinase	_	NOUN	_	Number=Sing	_	_	_	_
56	(	_	PUNCT	_	_	_	_	_	_
57	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
58	)	_	PUNCT	_	_	_	_	_	_
59	pathway	_	NOUN	_	Number=Sing	_	_	_	_
60	(	_	PUNCT	_	_	_	_	_	_
61	PD	_	NOUN	_	Number=Sing	_	_	_	_
62	98059	_	NUM	_	NumType=Card	_	_	_	_
63	)	_	PUNCT	_	_	_	_	_	_
64	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
65	not	_	PART	_	_	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	HIV	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	gp41	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	up	_	ADP	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	regulation	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	PI	_	NOUN	_	Number=Sing	_	_	_	_
27	3	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kinase	_	NOUN	_	Number=Sing	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	but	_	CCONJ	_	_	_	_	_	_
33	rather	_	ADV	_	_	_	_	_	_
34	may	_	AUX	_	VerbForm=Fin	_	_	_	_
35	operate	_	VERB	_	VerbForm=Inf	_	_	_	_
36	through	_	ADP	_	_	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	adenylate	_	NOUN	_	Degree=Pos	_	_	_	_
40	cyclase	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	pertussis	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	toxin	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
47	Gi	_	NOUN	_	Number=Sing	_	_	_	_
48	/	_	PUNCT	_	_	_	_	_	_
49	Go	_	NOUN	_	Number=Sing	_	_	_	_
50	protein	_	NOUN	_	Number=Sing	_	_	_	_
51	to	_	ADP	_	_	_	_	_	_
52	effect	_	NOUN	_	Number=Sing	_	_	_	_
53	p70	_	NOUN	_	Number=Sing	_	_	_	_
54	(	_	PUNCT	_	_	_	_	_	_
55	S6	_	NOUN	_	Number=Sing	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	kinase	_	NOUN	_	Number=Sing	_	_	_	_
59	activation	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002383	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Role	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IKK1	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	IKK2	_	PROPN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
8	signaling	_	VERB	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	major	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	immune	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	responses	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
2	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	LPS	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	express	_	VERB	_	VerbForm=Inf	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	variety	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	SCONJ	_	_	_	_	_	_
15	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	Rel	_	NOUN	_	Number=Sing	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	family	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	tumor	_	NOUN	_	Number=Sing	_	_	_	_
9	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	signaling	_	NOUN	_	Number=Sing	_	_	_	_
15	pathways	_	NOUN	_	Number=Plur	_	_	_	_
16	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	kinases	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	IKK1	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	IKK2	_	PROPN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
5	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
6	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	IkappaBbeta	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	IkappaBepsilon	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
17	kinases	_	NOUN	_	Number=Plur	_	_	_	_
18	triggers	_	VERB	_	Number=Plur	_	_	_	_
19	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
20	degradation	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	release	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	Rel	_	NOUN	_	Number=Sing	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	into	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IKKs	_	PROPN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	LPS	_	PROPN	_	Number=Sing	_	_	_	_
11	signaling	_	NOUN	_	Number=Sing	_	_	_	_
12	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
15	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	LPS	_	PROPN	_	Number=Sing	_	_	_	_
7	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	IKK	_	PROPN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	THP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	relatively	_	ADV	_	_	_	_	_	_
13	slow	_	ADJ	_	Degree=Pos	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	60	_	NUM	_	NumType=Card	_	_	_	_
20	min	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	coincides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	degradation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	IkappaBs	_	PROPN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
32	translocation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	wild	_	NOUN	_	Number=Sing	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	IKK1	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
13	negative	_	ADJ	_	Degree=Pos	_	_	_	_
14	mutant	_	NOUN	_	Number=Sing	_	_	_	_
15	IKK1	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	K44M	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	wild	_	ADJ	_	Degree=Pos	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	IKK2	_	PROPN	_	Number=Sing	_	_	_	_
24	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
27	LPS	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
6	negative	_	ADJ	_	Degree=Pos	_	_	_	_
7	mutant	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IKK2	_	PROPN	_	Number=Sing	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	LPS	_	PROPN	_	Number=Sing	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	dose	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	manner	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	LPS	_	NOUN	_	Number=Sing	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	IKK2	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002388	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	GABP	_	NOUN	_	Number=Sing	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	distal	_	ADJ	_	Degree=Pos	_	_	_	_
7	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	c	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	Raf	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	increase	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	induction	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Triggering	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	CD3	_	PROPN	_	Number=Sing	_	_	_	_
8	complex	_	NOUN	_	Number=Sing	_	_	_	_
9	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	major	_	ADJ	_	Degree=Pos	_	_	_	_
12	signal	_	NOUN	_	Number=Sing	_	_	_	_
13	cascades	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	i	_	X	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
22	+-	_	PUNCT	_	_	_	_	_	_
23	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
24	signal	_	NOUN	_	Number=Sing	_	_	_	_
25	cascades	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	ii	_	X	_	_	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	protein	_	NOUN	_	Number=Sing	_	_	_	_
31	kinase	_	NOUN	_	Number=Sing	_	_	_	_
32	cascades	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	signal	_	ADJ	_	Number=Sing	_	_	_	_
3	cascades	_	NOUN	_	Number=Plur	_	_	_	_
4	contribute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	_	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	during	_	ADP	_	_	_	_	_	_
19	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Prominent	_	ADJ	_	Degree=Pos	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	kinase	_	NOUN	_	Number=Sing	_	_	_	_
4	cascades	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
7	that	_	DET	_	PronType=Rel	_	_	_	_
8	activate	_	ADJ	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	MAP	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	kinases	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	DET	_	_	_	_	_	_
5	c-Raf	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	helm	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	classic	_	ADJ	_	Degree=Pos	_	_	_	_
15	MAP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	Erk	_	PROPN	_	Number=Sing	_	_	_	_
18	cascade	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	induction	_	NOUN	_	Number=Sing	_	_	_	_
26	through	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	distal	_	ADJ	_	Degree=Pos	_	_	_	_
29	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
30	element	_	NOUN	_	Number=Sing	_	_	_	_
31	spanning	_	VERB	_	VerbForm=Ger	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
34	from	_	ADP	_	_	_	_	_	_
35	positions	_	NOUN	_	Number=Plur	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	502	_	NUM	_	NumType=Card	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	-	_	SYM	_	_	_	_	_	_
40	413	_	NUM	_	NumType=Card	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	front	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
46	start	_	NOUN	_	Number=Sing	_	_	_	_
47	site	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	IL	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	2	_	NUM	_	NumType=Card	_	_	_	_
53	gene	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	distal	_	ADJ	_	Degree=Pos	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
9	differs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	since	_	SCONJ	_	_	_	_	_	_
23	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
28	esters	_	NOUN	_	Number=Plur	_	_	_	_
29	alone	_	ADJ	_	Degree=Pos	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	independent	_	ADJ	_	Degree=Pos	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
34	+	_	SYM	_	_	_	_	_	_
35	signals	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	studies	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	detected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	GABP	_	NOUN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	dyad	_	ADJ	_	Degree=Pos	_	_	_	_
23	symmetry	_	NOUN	_	Number=Sing	_	_	_	_
24	element	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	DSE	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	distal	_	ADJ	_	Number=Sing	_	_	_	_
31	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	which	_	PRON	_	PronType=Rel	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	formed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	palindromic	_	ADJ	_	Degree=Pos	_	_	_	_
38	binding	_	VERB	_	Number=Sing	_	_	_	_
39	sites	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	Ets	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	like	_	ADJ	_	Degree=Pos	_	_	_	_
44	factors	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Introduction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	point	_	NOUN	_	Number=Sing	_	_	_	_
4	mutations	_	NOUN	_	Number=Plur	_	_	_	_
5	suppressing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	GABP	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	DSE	_	PROPN	_	Number=Sing	_	_	_	_
11	interfered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	distal	_	ADJ	_	Number=Sing	_	_	_	_
18	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	entire	_	ADJ	_	Degree=Pos	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	while	_	SCONJ	_	_	_	_	_	_
30	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	both	_	DET	_	_	_	_	_	_
33	GABP	_	NOUN	_	Number=Sing	_	_	_	_
34	factors	_	NOUN	_	Number=Plur	_	_	_	_
35	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	promoter	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
43	induction	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	BXB	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
7	active	_	ADJ	_	Degree=Pos	_	_	_	_
8	version	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	c	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Raf	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	further	_	ADJ	_	Degree=Pos	_	_	_	_
17	members	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	Ras	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	Raf	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	Erk	_	PROPN	_	Number=Sing	_	_	_	_
25	signal	_	NOUN	_	Number=Sing	_	_	_	_
26	cascade	_	NOUN	_	Number=Sing	_	_	_	_
27	exerted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	increase	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	GABP	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
37	induction	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conjunction	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	previously	_	ADV	_	_	_	_	_	_
5	published	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	data	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	c-Raf	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	GABP	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	E.Flory	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	A.	_	PROPN	_	Number=Sing	_	_	_	_
19	Hoffmeyer	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	U.Smola	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	U.R.Rapp	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	J.T.	_	PROPN	_	Number=Sing	_	_	_	_
27	Bruder	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	J.Virol.70:2260	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	SYM	_	_	_	_	_	_
31	2268	_	NUM	_	NumType=Card	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	1996	_	NUM	_	NumType=Card	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
37	results	_	NOUN	_	Number=Plur	_	_	_	_
38	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	contribution	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	GABP	_	NOUN	_	Number=Sing	_	_	_	_
43	factors	_	NOUN	_	Number=Plur	_	_	_	_
44	to	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	Raf	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
49	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	IL	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	2	_	NUM	_	NumType=Card	_	_	_	_
54	induction	_	NOUN	_	Number=Sing	_	_	_	_
55	during	_	ADP	_	_	_	_	_	_
56	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
57	activation	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002389	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	cofactor	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	dimerization	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
11	homeodomain	_	NOUN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Dimerization	_	NOUN	_	Number=Sing	_	_	_	_
2	among	_	ADP	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	become	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	recurrent	_	ADJ	_	Degree=Pos	_	_	_	_
9	theme	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	eukaryotic	_	ADJ	_	Degree=Pos	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Hepatocyte	_	VERB	_	Number=Sing	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HNF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	homeodomain	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	that	_	DET	_	PronType=Rel	_	_	_	_
20	functions	_	NOUN	_	Number=Plur	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	dimer	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	dimerization	_	NOUN	_	Number=Sing	_	_	_	_
3	cofactor	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	HNF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	DCoH	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	displayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	tissue	_	NOUN	_	Number=Sing	_	_	_	_
19	distribution	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	DNA	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	rather	_	ADV	_	_	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	selectively	_	ADV	_	_	_	_	_	_
32	stabilized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	HNF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	dimers	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	formation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	stable	_	ADJ	_	Degree=Pos	_	_	_	_
6	tetrameric	_	ADJ	_	Number=Sing	_	_	_	_
7	DCoH	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	HNF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	complex	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	required	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	dimerization	_	NOUN	_	Number=Sing	_	_	_	_
19	domain	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	HNF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	change	_	VERB	_	VerbForm=Inf	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	DNA	_	PROPN	_	Number=Sing	_	_	_	_
31	binding	_	VERB	_	Number=Sing	_	_	_	_
32	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	HNF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	but	_	CCONJ	_	_	_	_	_	_
40	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
42	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
43	activity	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	DCoH	_	PROPN	_	Number=Sing	_	_	_	_
4	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	confer	_	VERB	_	VerbForm=Inf	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	GAL4	_	PROPN	_	Number=Sing	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	domain	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	DCoH	_	PROPN	_	Number=Sing	_	_	_	_
6	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	formation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	transcriptionally	_	ADV	_	_	_	_	_	_
10	active	_	ADJ	_	Degree=Pos	_	_	_	_
11	tetrameric	_	ADJ	_	Degree=Pos	_	_	_	_
12	complexes	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
19	specificity	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	complex	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002390	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	E3330	_	NUM	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	novel	_	NOUN	_	Number=Sing	_	_	_	_
8	quinone	_	NOUN	_	Number=Sing	_	_	_	_
9	derivative	_	NOUN	_	Number=Sing	_	_	_	_
10	able	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
13	tumor	_	NOUN	_	Number=Sing	_	_	_	_
14	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	generation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B.	_	PROPN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	2E	_	NUM	_	NumType=Card	_	_	_	_
30	)-3-[5-(2,3-Dimethoxy-6-methyl-1,4-benzoquinoyl)]-2-nonyl-2	_	PUNCT	_	NumType=Card	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	propenoic	_	NOUN	_	Number=Sing	_	_	_	_
33	acid	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	E3330	_	NUM	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	novel	_	NOUN	_	Number=Sing	_	_	_	_
41	agent	_	NOUN	_	Number=Sing	_	_	_	_
42	with	_	ADP	_	_	_	_	_	_
43	hepatoprotective	_	ADJ	_	Degree=Pos	_	_	_	_
44	activity	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	E3330	_	NUM	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	tumor	_	NOUN	_	Number=Sing	_	_	_	_
12	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TNF	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	run	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	experiments	_	NOUN	_	Number=Plur	_	_	_	_
6	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	E3330	_	NUM	_	Number=Sing	_	_	_	_
9	decreases	_	VERB	_	Number=Plur	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	TNF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	LPS	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
27	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
5	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	constructed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	type	_	NOUN	_	Number=Sing	_	_	_	_
13	placental	_	ADJ	_	Degree=Pos	_	_	_	_
14	alkaline	_	NOUN	_	Number=Sing	_	_	_	_
15	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	PLAP	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	reporter	_	NOUN	_	Number=Sing	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	1.4	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kb	_	NOUN	_	Number=Sing	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	TNF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	stable	_	ADJ	_	Degree=Pos	_	_	_	_
3	transformant	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	PLAP	_	NOUN	_	Number=Sing	_	_	_	_
7	reporter	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	line	_	NOUN	_	Number=Sing	_	_	_	_
15	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	very	_	ADV	_	_	_	_	_	_
17	little	_	ADJ	_	Degree=Pos	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	before	_	ADP	_	_	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	whereas	_	SCONJ	_	_	_	_	_	_
26	LPS	_	PROPN	_	Number=Sing	_	_	_	_
27	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
28	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
32	increase	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	PLAP	_	NOUN	_	Number=Sing	_	_	_	_
35	activity	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	E3330	_	NUM	_	Number=Sing	_	_	_	_
2	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	dose	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	manner	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	four	_	NUM	_	NumType=Card	_	_	_	_
4	putative	_	ADJ	_	Degree=Pos	_	_	_	_
5	NF	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	sites	_	NOUN	_	Number=Plur	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	3	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	4	_	NUM	_	NumType=Card	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	human	_	ADJ	_	Degree=Pos	_	_	_	_
34	TNF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	promoter	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	PLAP	_	NOUN	_	Number=Sing	_	_	_	_
7	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	established	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	sites	_	NOUN	_	Number=Plur	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	induction	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	TNF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	LPS	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	gel	_	NOUN	_	Number=Sing	_	_	_	_
3	retardation	_	NOUN	_	Number=Sing	_	_	_	_
4	experiment	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
7	double	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
11	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	consisting	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
21	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
22	bound	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	all	_	DET	_	_	_	_	_	_
25	four	_	NUM	_	NumType=Card	_	_	_	_
26	putative	_	ADJ	_	Degree=Pos	_	_	_	_
27	NF	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	DNA	_	NOUN	_	Number=Sing	_	_	_	_
32	probes	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
35	that	_	SCONJ	_	_	_	_	_	_
36	all	_	DET	_	_	_	_	_	_
37	four	_	NUM	_	NumType=Card	_	_	_	_
38	putative	_	ADJ	_	Degree=Pos	_	_	_	_
39	NF	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappa	_	NOUN	_	Number=Sing	_	_	_	_
42	B	_	NOUN	_	Number=Sing	_	_	_	_
43	recognition	_	NOUN	_	Number=Sing	_	_	_	_
44	sites	_	NOUN	_	Number=Plur	_	_	_	_
45	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
46	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
47	important	_	ADJ	_	Degree=Pos	_	_	_	_
48	role	_	NOUN	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
51	TNF	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	alpha	_	NOUN	_	Number=Sing	_	_	_	_
54	expression	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	E3330	_	NUM	_	NumType=Card	_	_	_	_
2	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	E3330	_	PROPN	_	Number=Sing	_	_	_	_
14	inhibits	_	VERB	_	Number=Plur	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	translocation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blotting	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	anti-I	_	PROPN	_	Number=Sing	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	PROPN	_	Number=Sing	_	_	_	_
10	antibody	_	NOUN	_	Number=Sing	_	_	_	_
11	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	E3330	_	PROPN	_	Number=Sing	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	degradation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	LPS	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	E3330	_	NUM	_	Number=Sing	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	production	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	active	_	ADJ	_	Degree=Pos	_	_	_	_
8	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
9	species	_	NOUN	_	Number=Plur	_	_	_	_
10	serving	_	VERB	_	VerbForm=Ger	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	common	_	ADJ	_	Degree=Pos	_	_	_	_
13	messengers	_	NOUN	_	Number=Plur	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	PROPN	_	Number=Sing	_	_	_	_
19	B.	_	PROPN	_	Number=Sing	_	_	_	_
20	Document	_	NOUN	_	Number=Sing	_	_	_	_
21	003002392	_	NUM	_	NumType=Card	_	_	_	_
22	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	6	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	Mycobacterium	_	PROPN	_	Number=Sing	_	_	_	_
9	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	IL6	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	PROPN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	[	_	PUNCT	_	_	_	_	_	_
26	published	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	erratum	_	NOUN	_	Number=Sing	_	_	_	_
28	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	Proc	_	PROPN	_	Number=Sing	_	_	_	_
31	Natl	_	PROPN	_	Number=Sing	_	_	_	_
32	Acad	_	PROPN	_	Number=Sing	_	_	_	_
33	Sci	_	PROPN	_	Number=Sing	_	_	_	_
34	U	_	PROPN	_	Number=Sing	_	_	_	_
35	S	_	PROPN	_	Number=Sing	_	_	_	_
36	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	1995	_	NUM	_	NumType=Card	_	_	_	_
38	Apr	_	PROPN	_	Number=Sing	_	_	_	_
39	11;92	_	NUM	_	NumType=Card	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	8):	_	NUM	_	_	_	_	_	_
42	3632	_	NUM	_	NumType=Card	_	_	_	_
43	]	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	host	_	NOUN	_	Number=Sing	_	_	_	_
3	response	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	Mycobacterium	_	PROPN	_	Number=Sing	_	_	_	_
6	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
7	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	granuloma	_	NOUN	_	Number=Sing	_	_	_	_
9	formation	_	NOUN	_	Number=Sing	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	sites	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	infection	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	systemic	_	ADJ	_	Degree=Pos	_	_	_	_
16	symptoms	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Cytokines	_	NOUN	_	Number=Plur	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	immunohistochemistry	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	granulomas	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	animal	_	NOUN	_	Number=Sing	_	_	_	_
11	models	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	bacillus	_	PROPN	_	Number=Sing	_	_	_	_
14	Calmette	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	Guerin	_	PROPN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	BCG	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	infection	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	released	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	upon	_	ADP	_	_	_	_	_	_
28	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	mycobacterial	_	ADJ	_	Degree=Pos	_	_	_	_
31	proteins	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	regard	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
7	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	6	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	play	_	VERB	_	VerbForm=Inf	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
21	manifestations	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	pathological	_	ADJ	_	Degree=Pos	_	_	_	_
24	events	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	tuberculosis	_	ADJ	_	Number=Sing	_	_	_	_
27	infection	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	lipoarabinomannan	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	LAM	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	mycobacterial	_	ADJ	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	wall	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	virtually	_	ADV	_	_	_	_	_	_
18	devoid	_	ADJ	_	Degree=Pos	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	LPS	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	release	_	VERB	_	VerbForm=Inf	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	6	_	NUM	_	NumType=Card	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	dose	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	response	_	NOUN	_	Number=Sing	_	_	_	_
38	manner	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	LAM	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	LPS	_	PROPN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	potent	_	ADJ	_	Degree=Pos	_	_	_	_
6	inducers	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
15	blood	_	NOUN	_	Number=Sing	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	LAM	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	LPS	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	DNA	_	NOUN	_	Number=Sing	_	_	_	_
18	fragment	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	positions	_	NOUN	_	Number=Plur	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	158	_	NUM	_	NumType=Card	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	-	_	SYM	_	_	_	_	_	_
25	49	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	deletion	_	NOUN	_	Number=Sing	_	_	_	_
29	analysis	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
32	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
33	assay	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	IL6	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	positions	_	NOUN	_	Number=Plur	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	153	_	NUM	_	NumType=Card	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	-	_	SYM	_	_	_	_	_	_
13	145	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	-	_	SYM	_	_	_	_	_	_
16	83	_	NUM	_	NumType=Card	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	-	_	SYM	_	_	_	_	_	_
19	75	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	one	_	NUM	_	NumType=Card	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	positions	_	NOUN	_	Number=Plur	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	72	_	NUM	_	NumType=Card	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	-	_	SYM	_	_	_	_	_	_
35	63	_	NUM	_	NumType=Card	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	motifs	_	NOUN	_	Number=Plur	_	_	_	_
38	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	present	_	ADJ	_	Degree=Pos	_	_	_	_
40	within	_	ADP	_	_	_	_	_	_
41	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
42	fragment	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Site	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	one	_	NUM	_	NumType=Card	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	more	_	ADJ	_	Degree=Cmp	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	motifs	_	NOUN	_	Number=Plur	_	_	_	_
12	within	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	6	_	NUM	_	NumType=Card	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	each	_	DET	_	_	_	_	_	_
21	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	positive	_	ADJ	_	Degree=Pos	_	_	_	_
23	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
28	could	_	AUX	_	VerbForm=Fin	_	_	_	_
29	act	_	VERB	_	VerbForm=Inf	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	function	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	orientation	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	independent	_	ADJ	_	Degree=Pos	_	_	_	_
38	manner	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	all	_	DET	_	_	_	_	_	_
4	three	_	NUM	_	NumType=Card	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	6	_	NUM	_	NumType=Card	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	LAM	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	LPS	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	IL6	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	sites	_	NOUN	_	Number=Plur	_	_	_	_
14	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	6	_	NUM	_	NumType=Card	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	response	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	LPS	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	LAM	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	mycobacterial	_	ADJ	_	Degree=Pos	_	_	_	_
32	response	_	NOUN	_	Number=Sing	_	_	_	_
33	elements	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002394	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Homodimerization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	chain	_	NOUN	_	Number=Sing	_	_	_	_
10	induces	_	VERB	_	Number=Plur	_	_	_	_
11	Cepsilon	_	NOUN	_	Number=Sing	_	_	_	_
12	germline	_	NOUN	_	Number=Sing	_	_	_	_
13	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	B	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	absence	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	gamma	_	NOUN	_	Number=Sing	_	_	_	_
26	chain	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cytokines	_	PROPN	_	Number=Plur	_	_	_	_
3	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	13	_	NUM	_	NumType=Card	_	_	_	_
13	play	_	VERB	_	VerbForm=Inf	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	critical	_	ADJ	_	Degree=Pos	_	_	_	_
16	role	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	SCONJ	_	_	_	_	_	_
18	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	Cepsilon	_	PROPN	_	Number=Sing	_	_	_	_
20	germline	_	NOUN	_	Number=Sing	_	_	_	_
21	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	IgE	_	PROPN	_	Number=Sing	_	_	_	_
24	isotype	_	NOUN	_	Number=Sing	_	_	_	_
25	switching	_	VERB	_	VerbForm=Ger	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	4	_	NUM	_	NumType=Card	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	4R	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	chains	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	4	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	binding	_	VERB	_	Number=Sing	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	4	_	NUM	_	NumType=Card	_	_	_	_
29	Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
30	chain	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	shared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	13R	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	IL	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	2Rgamma	_	NOUN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	gammac	_	NOUN	_	Number=Sing	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	chain	_	NOUN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	which	_	PRON	_	PronType=Rel	_	_	_	_
52	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
53	shared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
54	with	_	ADP	_	_	_	_	_	_
55	IL	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	7R	_	PROPN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	IL	_	PROPN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	9R	_	PROPN	_	Number=Sing	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	and	_	CCONJ	_	_	_	_	_	_
64	IL	_	PROPN	_	Number=Sing	_	_	_	_
65	-	_	PUNCT	_	_	_	_	_	_
66	15R	_	PROPN	_	Number=Sing	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	induces	_	NOUN	_	Number=Plur	_	_	_	_
5	Cepsilon	_	PROPN	_	Number=Sing	_	_	_	_
6	germline	_	NOUN	_	Number=Sing	_	_	_	_
7	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	IgE	_	PROPN	_	Number=Sing	_	_	_	_
10	isotype	_	NOUN	_	Number=Sing	_	_	_	_
11	switching	_	VERB	_	VerbForm=Ger	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	B	_	ADJ	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	patients	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	gammac	_	NOUN	_	Number=Sing	_	_	_	_
19	chain	_	NOUN	_	Number=Sing	_	_	_	_
20	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Cepsilon	_	PROPN	_	Number=Sing	_	_	_	_
4	germline	_	NOUN	_	Number=Sing	_	_	_	_
5	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	4	_	NUM	_	NumType=Card	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	lack	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	gammac	_	NOUN	_	Number=Sing	_	_	_	_
17	chain	_	NOUN	_	Number=Sing	_	_	_	_
18	may	_	AUX	_	VerbForm=Fin	_	_	_	_
19	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
20	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
21	via	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	13R	_	NOUN	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Alternatively	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
8	chain	_	NOUN	_	Number=Sing	_	_	_	_
9	may	_	AUX	_	VerbForm=Fin	_	_	_	_
10	transduce	_	VERB	_	VerbForm=Inf	_	_	_	_
11	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
12	signals	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	Cepsilon	_	PROPN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	independently	_	ADV	_	_	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	association	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	other	_	ADJ	_	Degree=Pos	_	_	_	_
25	chains	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	ligand	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	homodimerization	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	chimeric	_	ADJ	_	Degree=Pos	_	_	_	_
10	surface	_	NOUN	_	Number=Sing	_	_	_	_
11	receptors	_	NOUN	_	Number=Plur	_	_	_	_
12	consisting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	transmembrane	_	ADJ	_	Number=Sing	_	_	_	_
18	domains	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
27	domain	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	4Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
32	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	Janus	_	PROPN	_	Number=Sing	_	_	_	_
34	kinase	_	NOUN	_	Number=Sing	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
42	activation	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	Cepsilon	_	PROPN	_	Number=Sing	_	_	_	_
46	germline	_	NOUN	_	Number=Sing	_	_	_	_
47	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	human	_	ADJ	_	Degree=Pos	_	_	_	_
50	B	_	NOUN	_	Number=Sing	_	_	_	_
51	cell	_	NOUN	_	Number=Sing	_	_	_	_
52	line	_	NOUN	_	Number=Sing	_	_	_	_
53	BJAB	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Disruption	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	proline	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	rich	_	ADJ	_	Number=Sing	_	_	_	_
10	Box1	_	NOUN	_	Number=Sing	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	4Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
16	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	signaling	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	chimeric	_	ADJ	_	Degree=Pos	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	B	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	chimeric	_	ADJ	_	Number=Sing	_	_	_	_
9	CD8alpha	_	PROPN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	surface	_	NOUN	_	Number=Sing	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	constitutively	_	ADV	_	_	_	_	_	_
29	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	Cepsilon	_	NOUN	_	Number=Sing	_	_	_	_
31	germline	_	NOUN	_	Number=Sing	_	_	_	_
32	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	homodimerization	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
12	chain	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	transduce	_	VERB	_	VerbForm=Inf	_	_	_	_
17	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
21	signals	_	NOUN	_	Number=Plur	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	IgE	_	PROPN	_	Number=Sing	_	_	_	_
26	isotype	_	NOUN	_	Number=Sing	_	_	_	_
27	switching	_	VERB	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002395	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	class	_	NOUN	_	Number=Sing	_	_	_	_
3	II	_	NUM	_	NumType=Card	_	_	_	_
4	trans	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activator	_	NOUN	_	Number=Sing	_	_	_	_
7	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
8	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	TBP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	TAFII32	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	class	_	NOUN	_	Number=Sing	_	_	_	_
3	II	_	NUM	_	Number=Sing	_	_	_	_
4	trans	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activator	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	main	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	co-activator	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	MHC	_	PROPN	_	Number=Sing	_	_	_	_
20	class	_	NOUN	_	Number=Sing	_	_	_	_
21	II	_	NUM	_	Number=Sing	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	N-terminal	_	ADJ	_	Number=Sing	_	_	_	_
3	125	_	NUM	_	NumType=Card	_	_	_	_
4	amino	_	ADJ	_	Number=Sing	_	_	_	_
5	acids	_	NOUN	_	Number=Plur	_	_	_	_
6	function	_	NOUN	_	Number=Sing	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	independent	_	ADJ	_	Degree=Pos	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	domain	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Analyses	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	primary	_	ADJ	_	Degree=Pos	_	_	_	_
5	amino	_	NOUN	_	Number=Sing	_	_	_	_
6	acid	_	VERB	_	Number=Sing	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	domain	_	NOUN	_	Number=Sing	_	_	_	_
12	predict	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	presence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	three	_	NUM	_	NumType=Card	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	helices	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	each	_	DET	_	_	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	high	_	ADJ	_	Degree=Pos	_	_	_	_
25	proportion	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	acidic	_	ADJ	_	Degree=Pos	_	_	_	_
28	residues	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	site	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	predicted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	helices	_	NOUN	_	Number=Plur	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	full	_	ADJ	_	Degree=Pos	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	both	_	DET	_	_	_	_	_	_
9	functional	_	ADJ	_	Degree=Pos	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	helices	_	NOUN	_	Number=Plur	_	_	_	_
13	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
15	deleted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	displays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
19	negative	_	ADJ	_	Degree=Pos	_	_	_	_
20	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	domain	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
6	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	32	_	NUM	_	NumType=Card	_	_	_	_
10	kDa	_	NOUN	_	Number=Sing	_	_	_	_
11	subunit	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	general	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	complex	_	NOUN	_	Number=Sing	_	_	_	_
17	TFIID	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	TAFII32	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	N	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	terminal	_	NOUN	_	Number=Sing	_	_	_	_
8	deletions	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	directly	_	ADV	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	TAFII32	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	interactions	_	NOUN	_	Number=Plur	_	_	_	_
5	between	_	ADP	_	_	_	_	_	_
6	TAFII32	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	class	_	NOUN	_	Number=Sing	_	_	_	_
15	II	_	NUM	_	Number=Sing	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002398	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	normal	_	ADJ	_	Degree=Pos	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
13	blood	_	NOUN	_	Number=Sing	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Convergence	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	signals	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	differences	_	NOUN	_	Number=Plur	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	study	_	VERB	_	VerbForm=Inf	_	_	_	_
3	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	normal	_	ADJ	_	Degree=Pos	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	optimized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	conditions	_	NOUN	_	Number=Plur	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	transient	_	ADJ	_	Degree=Pos	_	_	_	_
17	transfection	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-2	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	X	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	reporter	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	behavior	_	NOUN	_	Number=Sing	_	_	_	_
12	closely	_	ADV	_	_	_	_	_	_
13	parallels	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	signals	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	assessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	mutagenized	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
5	promoters	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	most	_	ADV	_	_	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	cis	_	NOUN	_	Number=Plur	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	elements	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
24	AP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	site	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
33	site	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	primary	_	ADJ	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	CD3	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	provided	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	pairs	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	CD2	_	NOUN	_	Number=Sing	_	_	_	_
20	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	B7	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	positive	_	ADJ	_	Degree=Pos	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	B	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	B7	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	negative	_	NOUN	_	Degree=Pos	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	accessory	_	ADJ	_	Degree=Pos	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	through	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	same	_	ADJ	_	Degree=Pos	_	_	_	_
44	cis-elements	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	sites	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	much	_	ADV	_	_	_	_	_	_
13	less	_	ADV	_	Degree=Cmp	_	_	_	_
14	important	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	normal	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	than	_	ADP	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	differs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	tumor	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	lines	_	NOUN	_	Number=Plur	_	_	_	_
14	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	normal	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	that	_	DET	_	_	_	_	_	_
21	different	_	ADJ	_	Degree=Pos	_	_	_	_
22	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	signals	_	NOUN	_	Number=Plur	_	_	_	_
24	converge	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	same	_	ADJ	_	Degree=Pos	_	_	_	_
28	cis	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	elements	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002407	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	mediated	_	VERB	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	cycle	_	NOUN	_	Number=Sing	_	_	_	_
8	progression	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
13	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	require	_	VERB	_	VerbForm=Inf	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	primary	_	ADJ	_	Degree=Pos	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	T	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	growth	_	NOUN	_	Number=Sing	_	_	_	_
6	hormone	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	major	_	ADJ	_	Degree=Pos	_	_	_	_
10	growth	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	during	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	developing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	immune	_	ADJ	_	Degree=Pos	_	_	_	_
20	response	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	not	_	ADV	_	_	_	_	_	_
7	only	_	ADV	_	_	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	cycle	_	NOUN	_	Number=Sing	_	_	_	_
11	progression	_	NOUN	_	Number=Sing	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	protect	_	VERB	_	VerbForm=Inf	_	_	_	_
16	Ag	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	programmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	death	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	several	_	ADJ	_	Degree=Pos	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	types	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	activating	_	VERB	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	be	_	AUX	_	VerbForm=Inf	_	_	_	_
29	extremely	_	ADV	_	_	_	_	_	_
30	important	_	ADJ	_	Degree=Pos	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	blocking	_	NOUN	_	Number=Sing	_	_	_	_
33	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	either	_	DET	_	_	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	both	_	DET	_	_	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	involved	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	survival	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	cycle	_	NOUN	_	Number=Sing	_	_	_	_
19	progression	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	primary	_	ADJ	_	Degree=Pos	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	T	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	growth	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappa	_	NOUN	_	Number=Sing	_	_	_	_
42	B	_	NOUN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	AP	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	activation	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	current	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	clearly	_	ADV	_	_	_	_	_	_
5	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	kappa	_	VERB	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	degradation	_	NOUN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	PROPN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	primary	_	ADJ	_	Degree=Pos	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	respond	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	by	_	SCONJ	_	_	_	_	_	_
36	entering	_	VERB	_	VerbForm=Ger	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	cycle	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	avoiding	_	VERB	_	VerbForm=Ger	_	_	_	_
42	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Similarly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	neither	_	CCONJ	_	_	_	_	_	_
7	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	JNK	_	PROPN	_	Number=Sing	_	_	_	_
9	nor	_	CCONJ	_	_	_	_	_	_
10	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	binding	_	VERB	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	consensus	_	NOUN	_	Number=Sing	_	_	_	_
19	o-tetradecanoylphorbol	_	NOUN	_	Number=Sing	_	_	_	_
20	13	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	acetate	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	TPA	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	response	_	NOUN	_	Number=Sing	_	_	_	_
27	element	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	hand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	growth	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	as	_	SCONJ	_	_	_	_	_	_
22	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	previously	_	ADV	_	_	_	_	_	_
25	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	neither	_	CCONJ	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	PROPN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	nor	_	CCONJ	_	_	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
23	survival	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	cycle	_	NOUN	_	Number=Sing	_	_	_	_
27	progression	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	primary	_	ADJ	_	Degree=Pos	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002409	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
6	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
8	Oct	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	precursor	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	POU	_	NOUN	_	Number=Sing	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	Oct	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	Oct	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	octamer	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	promoters	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	including	_	VERB	_	VerbForm=Ger	_	_	_	_
22	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
23	that	_	DET	_	PronType=Rel	_	_	_	_
24	direct	_	ADJ	_	Degree=Pos	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	rearranged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
29	genes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Unlike	_	ADP	_	_	_	_	_	_
2	Oct	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	constitutively	_	ADV	_	_	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	many	_	ADJ	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	types	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	Oct	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	primarily	_	ADV	_	_	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	B	_	NOUN	_	Degree=Pos	_	_	_	_
24	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	can	_	AUX	_	VerbForm=Fin	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	precursor	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	ADJ	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
37	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	LPS	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	precise	_	ADJ	_	Degree=Pos	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
11	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	monitored	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	Oct	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	arrested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	LPS	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
27	member	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	Rel	_	NOUN	_	Number=Sing	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	family	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Despite	_	ADP	_	_	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	LPS	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	disruption	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	signaling	_	NOUN	_	Number=Sing	_	_	_	_
13	pathway	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	precursor	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	loss	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
24	Oct	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	DNA	_	NOUN	_	Number=Sing	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	vitro	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	suppression	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	Oct	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	transcription	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	vivo	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
3	defect	_	NOUN	_	Number=Sing	_	_	_	_
4	correlated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	block	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	Oct	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	level	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whereas	_	SCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	Oct	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	finding	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	Oct	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	under	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	control	_	NOUN	_	Number=Sing	_	_	_	_
13	highlights	_	VERB	_	Number=Plur	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	important	_	ADJ	_	Degree=Pos	_	_	_	_
16	cross	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	talk	_	NOUN	_	Number=Sing	_	_	_	_
19	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
20	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
21	two	_	NUM	_	NumType=Card	_	_	_	_
22	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	families	_	NOUN	_	Number=Plur	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	B	_	ADJ	_	Number=Sing	_	_	_	_
29	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
30	function	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002412	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	10	_	NUM	_	NumType=Card	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	divergent	_	ADJ	_	Degree=Pos	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	kinases	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	potent	_	ADJ	_	Degree=Pos	_	_	_	_
7	mediator	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	plasma	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	formation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	signal	_	ADJ	_	Number=Sing	_	_	_	_
4	transduction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	10	_	NUM	_	NumType=Card	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	B	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	poorly	_	ADV	_	_	_	_	_	_
14	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	protooncogene	_	NOUN	_	Number=Sing	_	_	_	_
16	c	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	fos	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	because	_	SCONJ	_	_	_	_	_	_
23	Fos	_	PROPN	_	Number=Sing	_	_	_	_
24	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	potential	_	ADJ	_	Degree=Pos	_	_	_	_
27	role	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	regulation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	B	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	purified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	buffy	_	NOUN	_	Number=Sing	_	_	_	_
7	coat	_	NOUN	_	Number=Sing	_	_	_	_
8	preparations	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
11	blood	_	NOUN	_	Number=Sing	_	_	_	_
12	donors	_	NOUN	_	Number=Plur	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	positive	_	ADJ	_	Degree=Pos	_	_	_	_
15	selection	_	NOUN	_	Number=Sing	_	_	_	_
16	using	_	VERB	_	VerbForm=Ger	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	anti	_	X	_	_	_	_	_	_
19	CD20	_	NOUN	_	Number=Sing	_	_	_	_
20	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
21	antibody	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	MiniMACS	_	PROPN	_	Number=Sing	_	_	_	_
25	separation	_	NOUN	_	Number=Sing	_	_	_	_
26	unit	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	B	_	SCONJ	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	prestimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	SAC	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	48	_	NUM	_	NumType=Card	_	_	_	_
9	hrs	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Then	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	incubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	medium	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	10	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	100	_	NUM	_	NumType=Card	_	_	_	_
14	ng	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	SYM	_	_	_	_	_	_
16	ml	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	10	_	NUM	_	NumType=Card	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	120	_	NUM	_	NumType=Card	_	_	_	_
22	min	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	RNA	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	extracted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	phenol	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	chloroform	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	c	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	fos	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	PCR	_	NOUN	_	Number=Sing	_	_	_	_
17	assisted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
19	assay	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	significant	_	ADJ	_	Degree=Pos	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	SYM	_	_	_	_	_	_
5	4	_	NUM	_	NumType=Card	_	_	_	_
6	fold	_	NOUN	_	Number=Sing	_	_	_	_
7	increase	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	c	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	fos	_	ADP	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	within	_	ADP	_	_	_	_	_	_
16	30	_	NUM	_	NumType=Card	_	_	_	_
17	min	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	10	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	p	_	NOUN	_	Number=Sing	_	_	_	_
26	<	_	PUNCT	_	_	_	_	_	_
27	0.01	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	2	_	NUM	_	NumType=Card	_	_	_	_
3	hrs	_	NOUN	_	Number=Plur	_	_	_	_
4	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	declined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	basal	_	ADJ	_	Degree=Pos	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	10	_	NUM	_	NumType=Card	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	dose	_	ADV	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	maximum	_	ADJ	_	Degree=Pos	_	_	_	_
14	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
15	using	_	VERB	_	VerbForm=Ger	_	_	_	_
16	100	_	NUM	_	NumType=Card	_	_	_	_
17	ng	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	ml	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	10	_	NUM	_	NumType=Card	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	10	_	NUM	_	NumType=Card	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	c	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	fos	_	ADP	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	polymyxin	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_
5	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
6	genistein	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	10	_	NUM	_	NumType=Card	_	_	_	_
9	microM	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	complete	_	ADJ	_	Degree=Pos	_	_	_	_
13	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	10	_	NUM	_	NumType=Card	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	H-7	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	10	_	NUM	_	NumType=Card	_	_	_	_
7	microM	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	serine	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	threonine	_	NOUN	_	Number=Sing	_	_	_	_
17	kinases	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	significantly	_	ADV	_	_	_	_	_	_
20	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	10	_	NUM	_	NumType=Card	_	_	_	_
24	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
25	c	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	fos	_	ADP	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	p	_	NOUN	_	Number=Sing	_	_	_	_
31	<	_	PUNCT	_	_	_	_	_	_
32	0.05	_	NUM	_	NumType=Card	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	induces	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	c	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	fos	_	ADP	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	serine	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	threonine	_	NOUN	_	Number=Sing	_	_	_	_
29	kinases	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	report	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	signal	_	NOUN	_	Number=Sing	_	_	_	_
13	transduction	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
16	data	_	NOUN	_	Number=Sing	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	help	_	VERB	_	VerbForm=Inf	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
23	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	10	_	NUM	_	NumType=Card	_	_	_	_
29	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002422	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	GM	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	CSF	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	share	_	NOUN	_	Number=Sing	_	_	_	_
9	common	_	ADJ	_	Degree=Pos	_	_	_	_
10	control	_	NOUN	_	Number=Sing	_	_	_	_
11	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	signals	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Antigen	_	PROPN	_	Number=Sing	_	_	_	_
2	complexed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	major	_	ADJ	_	Degree=Pos	_	_	_	_
5	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
6	complex	_	NOUN	_	Number=Sing	_	_	_	_
7	class	_	NOUN	_	Number=Sing	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	II	_	NUM	_	NumType=Card	_	_	_	_
11	molecules	_	NOUN	_	Number=Plur	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	surface	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	antigen	_	NOUN	_	Number=Sing	_	_	_	_
17	presenting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	TCR	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	surface	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	T	_	PROPN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	initiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	cascade	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	So	_	ADV	_	_	_	_	_	_
2	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	signals	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	other	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	surface	_	NOUN	_	Number=Sing	_	_	_	_
11	interactions	_	NOUN	_	Number=Plur	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
14	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
15	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	antigen	_	ADJ	_	Number=Sing	_	_	_	_
18	presenting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	also	_	ADV	_	_	_	_	_	_
23	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	complete	_	ADJ	_	Degree=Pos	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	High	_	ADJ	_	Degree=Pos	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	also	_	ADV	_	_	_	_	_	_
11	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	TCR	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	signals	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
5	colony	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	sequences	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	as	_	ADV	_	_	_	_	_	_
15	well	_	ADV	_	Degree=Pos	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	powerful	_	ADJ	_	Degree=Pos	_	_	_	_
19	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
20	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	3	_	NUM	_	NumType=Card	_	_	_	_
22	kb	_	NOUN	_	Number=Sing	_	_	_	_
23	upstream	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	TCR	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	like	_	ADP	_	Degree=Pos	_	_	_	_
30	signals	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	promoter	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
5	regions	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	mainly	_	ADV	_	_	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	TCR	_	NOUN	_	Number=Sing	_	_	_	_
7	signals	_	NOUN	_	Number=Plur	_	_	_	_
8	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	well	_	ADV	_	Degree=Pos	_	_	_	_
11	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	T	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
2	signals	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	such	_	ADJ	_	Degree=Pos	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	CD28	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	surface	_	NOUN	_	Number=Sing	_	_	_	_
12	molecule	_	NOUN	_	Number=Sing	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	lead	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
23	region	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
29	colony	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	GM	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	CSF	_	PROPN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	promoter	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	termed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	CK	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	CD28RE	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	members	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	family	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	factors	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	infects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	T	_	ADJ	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	can	_	AUX	_	VerbForm=Fin	_	_	_	_
17	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
20	GM	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	CSF	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	tax	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	signal	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	GM	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	CSF	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	in	_	SCONJ	_	_	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
33	can	_	AUX	_	VerbForm=Fin	_	_	_	_
34	cooperate	_	VERB	_	VerbForm=Inf	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	TCR	_	NOUN	_	Number=Sing	_	_	_	_
37	signals	_	NOUN	_	Number=Plur	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
40	high	_	ADJ	_	Degree=Pos	_	_	_	_
41	level	_	NOUN	_	Number=Sing	_	_	_	_
42	gene	_	NOUN	_	Number=Sing	_	_	_	_
43	expression	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	GM	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	CSF	_	NOUN	_	Number=Sing	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	CK	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1/CD28RE	_	PROPN	_	Number=Sing	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	region	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	coactivators	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	tax	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	but	_	CCONJ	_	_	_	_	_	_
19	these	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
20	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CK	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1/CD28RE	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	GM	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	CSF	_	PROPN	_	Number=Sing	_	_	_	_
9	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	high	_	ADJ	_	Degree=Pos	_	_	_	_
12	degree	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	similarity	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	CD28RE	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	3	_	NUM	_	NumType=Card	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	also	_	ADV	_	_	_	_	_	_
28	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	related	_	ADJ	_	Degree=Pos	_	_	_	_
31	region	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	observation	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	together	_	ADV	_	_	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	fact	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	GM	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	CSF	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	respond	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	TCR	_	NOUN	_	Number=Sing	_	_	_	_
20	signals	_	NOUN	_	Number=Plur	_	_	_	_
21	via	_	ADP	_	_	_	_	_	_
22	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	implies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	high	_	ADJ	_	Degree=Pos	_	_	_	_
27	degree	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	conservation	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	regulation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	T	_	PROPN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002426	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	7	_	NUM	_	NumType=Card	_	_	_	_
4	reconstitutes	_	VERB	_	Number=Plur	_	_	_	_
5	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
6	aspects	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	v-	_	PUNCT	_	_	_	_	_	_
9	Abl	_	ADJ	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	VERB	_	Degree=Pos	_	_	_	_
12	signaling	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	early	_	ADJ	_	Degree=Pos	_	_	_	_
6	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	selectively	_	ADV	_	_	_	_	_	_
10	transformed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	v-Abl	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	currently	_	ADV	_	_	_	_	_	_
15	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	7	_	NUM	_	NumType=Card	_	_	_	_
15	signaling	_	NOUN	_	Number=Sing	_	_	_	_
16	pathways	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	as	_	SCONJ	_	_	_	_	_	_
19	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	Janus	_	PROPN	_	Number=Sing	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	kinase	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	JAK	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	JAK3	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	by	_	ADP	_	_	_	_	_	_
43	v-Abl	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	signaling	_	VERB	_	Number=Sing	_	_	_	_
9	pathways	_	NOUN	_	Number=Plur	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	v-	_	PUNCT	_	_	_	_	_	_
12	Abl	_	PROPN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	important	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	events	_	NOUN	_	Number=Plur	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	Abelson	_	PROPN	_	Number=Sing	_	_	_	_
23	murine	_	PROPN	_	Number=Sing	_	_	_	_
24	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
25	virus	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	effects	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	4	_	NUM	_	NumType=Card	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	7	_	NUM	_	NumType=Card	_	_	_	_
37	on	_	ADP	_	_	_	_	_	_
38	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	with	_	ADP	_	_	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	temperature	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
46	v-	_	PUNCT	_	_	_	_	_	_
47	Abl	_	NOUN	_	Number=Sing	_	_	_	_
48	mutant	_	NOUN	_	Number=Sing	_	_	_	_
49	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
50	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	4	_	NUM	_	NumType=Card	_	_	_	_
5	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	little	_	ADJ	_	Degree=Pos	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	no	_	DET	_	_	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	7	_	NUM	_	NumType=Card	_	_	_	_
14	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	cycle	_	NOUN	_	Number=Sing	_	_	_	_
21	arrest	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	occur	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	upon	_	ADP	_	_	_	_	_	_
25	v-	_	ADJ	_	_	_	_	_	_
26	Abl	_	PROPN	_	Number=Sing	_	_	_	_
27	kinase	_	NOUN	_	Number=Sing	_	_	_	_
28	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	7	_	NUM	_	NumType=Card	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	delayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	decreases	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	c-Myc	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	xL	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	occur	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	upon	_	ADP	_	_	_	_	_	_
25	loss	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	v	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	Abl	_	NOUN	_	Number=Sing	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	activity	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	7	_	NUM	_	NumType=Card	_	_	_	_
4	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	maintain	_	VERB	_	VerbForm=Inf	_	_	_	_
7	v-	_	PUNCT	_	_	_	_	_	_
8	Abl	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	VERB	_	Degree=Pos	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	arrest	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	RAG	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	unaffected	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	7	_	NUM	_	NumType=Card	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	potential	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	7	_	NUM	_	NumType=Card	_	_	_	_
11	signaling	_	NOUN	_	Number=Sing	_	_	_	_
12	pathways	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	transformation	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	v	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	Abl	_	PROPN	_	Number=Sing	_	_	_	_
19	while	_	SCONJ	_	_	_	_	_	_
20	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	combination	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	4	_	NUM	_	NumType=Card	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	7	_	NUM	_	NumType=Card	_	_	_	_
32	signaling	_	NOUN	_	Number=Sing	_	_	_	_
33	can	_	AUX	_	VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	substitute	_	VERB	_	VerbForm=Inf	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	active	_	ADJ	_	Degree=Pos	_	_	_	_
39	v-	_	PUNCT	_	_	_	_	_	_
40	Abl	_	NOUN	_	Number=Sing	_	_	_	_
41	kinase	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002431	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	primary	_	ADJ	_	Degree=Pos	_	_	_	_
9	adult	_	NOUN	_	Number=Sing	_	_	_	_
10	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
11	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	etiologic	_	ADJ	_	Degree=Pos	_	_	_	_
15	agent	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	adult	_	NOUN	_	Number=Sing	_	_	_	_
18	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
19	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	ATL	_	PROPN	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	viral	_	ADJ	_	Degree=Pos	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	Tax	_	NOUN	_	Number=Sing	_	_	_	_
5	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	translocalization	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	proposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	play	_	VERB	_	VerbForm=Inf	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
25	role	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	transformation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	T	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	genes	_	NOUN	_	Number=Plur	_	_	_	_
8	including	_	VERB	_	VerbForm=Ger	_	_	_	_
9	Tax	_	NOUN	_	Number=Sing	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	significantly	_	ADV	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	primary	_	ADJ	_	Degree=Pos	_	_	_	_
16	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	ATL	_	DET	_	Number=Sing	_	_	_	_
20	patients	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	basis	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	freshly	_	ADV	_	_	_	_	_	_
16	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	ATL	_	ADJ	_	Number=Sing	_	_	_	_
21	patients	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	ATL	_	NOUN	_	Number=Sing	_	_	_	_
8	patients	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	like	_	ADP	_	_	_	_	_	_
11	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
17	lines	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	display	_	VERB	_	Number=Sing	_	_	_	_
20	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
21	NF	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	DNA	_	NOUN	_	Number=Sing	_	_	_	_
25	binding	_	VERB	_	Number=Sing	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	degradation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	Tax	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
13	lines	_	NOUN	_	Number=Plur	_	_	_	_
14	consisted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	mostly	_	ADV	_	_	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	p50/c	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	Rel	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	fresh	_	ADJ	_	Degree=Pos	_	_	_	_
22	ATL	_	NOUN	_	Number=Sing	_	_	_	_
23	samples	_	NOUN	_	Number=Plur	_	_	_	_
24	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	p50/p50	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
28	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
3	line	_	NOUN	_	Number=Sing	_	_	_	_
4	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	ATL	_	PROPN	_	Number=Sing	_	_	_	_
7	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	TL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Om1	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	displayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
16	NF	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	as	_	ADV	_	_	_	_	_	_
22	well	_	ADV	_	Degree=Pos	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	degradation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	despite	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	lack	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
34	Tax	_	NOUN	_	Number=Sing	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	TL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	Om1	_	PROPN	_	Number=Sing	_	_	_	_
11	consists	_	VERB	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	p50/p50	_	NOUN	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
16	like	_	ADP	_	_	_	_	_	_
17	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	fresh	_	ADJ	_	Degree=Pos	_	_	_	_
20	primary	_	ADJ	_	Degree=Pos	_	_	_	_
21	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	Tax	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	independent	_	ADJ	_	Degree=Pos	_	_	_	_
16	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	ATL	_	NOUN	_	Number=Sing	_	_	_	_
22	patients	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	possibly	_	ADV	_	_	_	_	_	_
25	due	_	ADP	_	_	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	differential	_	ADJ	_	Degree=Pos	_	_	_	_
28	NF	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	subunit	_	NOUN	_	Number=Sing	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002435	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	product	_	NOUN	_	Number=Sing	_	_	_	_
5	negatively	_	ADV	_	_	_	_	_	_
6	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	cytomegalovirus	_	NOUN	_	Number=Sing	_	_	_	_
14	IE2	_	PROPN	_	Number=Sing	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IE2	_	PROPN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	product	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	cytomegalovirus	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HCMV	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	one	_	NUM	_	NumType=Card	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	few	_	ADJ	_	Degree=Pos	_	_	_	_
16	viral	_	ADJ	_	Degree=Pos	_	_	_	_
17	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	immediately	_	ADV	_	_	_	_	_	_
21	upon	_	ADP	_	_	_	_	_	_
22	infection	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	host	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	potent	_	ADJ	_	Degree=Pos	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	activator	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	many	_	ADJ	_	Degree=Pos	_	_	_	_
9	viral	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
12	promoters	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
6	susceptibility	_	NOUN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	product	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	Rb	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	dramatically	_	ADV	_	_	_	_	_	_
13	suppressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
15	IE2	_	PROPN	_	Number=Sing	_	_	_	_
16	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	various	_	ADJ	_	Degree=Pos	_	_	_	_
19	promoters	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	unlike	_	ADP	_	_	_	_	_	_
4	another	_	DET	_	_	_	_	_	_
5	tumor	_	NOUN	_	Number=Sing	_	_	_	_
6	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	p53	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	Rb	_	PROPN	_	Number=Sing	_	_	_	_
12	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	have	_	VERB	_	VerbForm=Inf	_	_	_	_
15	any	_	DET	_	_	_	_	_	_
16	significant	_	ADJ	_	Degree=Pos	_	_	_	_
17	effect	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	basal	_	ADJ	_	Degree=Pos	_	_	_	_
20	levels	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	Rb	_	PROPN	_	Number=Sing	_	_	_	_
27	specifically	_	ADV	_	_	_	_	_	_
28	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	IE2	_	NOUN	_	Number=Sing	_	_	_	_
31	rather	_	ADV	_	_	_	_	_	_
32	than	_	ADP	_	_	_	_	_	_
33	other	_	ADJ	_	Degree=Pos	_	_	_	_
34	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
35	factors	_	NOUN	_	Number=Plur	_	_	_	_
36	involved	_	ADJ	_	Degree=Pos	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	general	_	ADJ	_	Degree=Pos	_	_	_	_
40	transcription	_	NOUN	_	Number=Sing	_	_	_	_
41	machinery	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	affinity	_	NOUN	_	Number=Sing	_	_	_	_
7	chromatography	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	Rb	_	PROPN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	extracts	_	NOUN	_	Number=Plur	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	vitro	_	NOUN	_	Number=Sing	_	_	_	_
18	translation	_	NOUN	_	Number=Sing	_	_	_	_
19	directly	_	ADV	_	_	_	_	_	_
20	bound	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	IE2	_	PROPN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Rb	_	PROPN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	life	_	NOUN	_	Number=Sing	_	_	_	_
10	cycle	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	HCMV	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	endemic	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	population	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	may	_	AUX	_	VerbForm=Fin	_	_	_	_
6	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
7	new	_	ADJ	_	Degree=Pos	_	_	_	_
8	insights	_	NOUN	_	Number=Plur	_	_	_	_
9	into	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	slow	_	ADJ	_	Degree=Pos	_	_	_	_
12	rate	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	HCMV	_	PROPN	_	Number=Sing	_	_	_	_
15	DNA	_	NOUN	_	Number=Sing	_	_	_	_
16	replication	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	possible	_	ADJ	_	Degree=Pos	_	_	_	_
22	involvement	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	HCMV	_	PROPN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	tumorigenesis	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002440	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Fas	_	NOUN	_	Number=Sing	_	_	_	_
4	ligand	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	death	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Programmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	death	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	process	_	NOUN	_	Number=Sing	_	_	_	_
7	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	normal	_	ADJ	_	Degree=Pos	_	_	_	_
11	development	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	organism	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	best	_	ADJ	_	Degree=Sup	_	_	_	_
5	understood	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
7	pathways	_	NOUN	_	Number=Plur	_	_	_	_
8	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	Fas	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	Fas	_	NOUN	_	Number=Sing	_	_	_	_
19	ligand	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	FasL	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	interaction	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	During	_	ADP	_	_	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	engagement	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	ALG	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	4F	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	transcript	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	T	_	NOUN	_	NumType=Card	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	FasL	_	ADJ	_	Degree=Pos	_	_	_	_
31	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	death	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	full	_	ADJ	_	Degree=Pos	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	length	_	NOUN	_	Number=Sing	_	_	_	_
6	ALG	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	FasL	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	consequently	_	ADV	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	ALG	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	FasL	_	ADJ	_	Degree=Pos	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Fas	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	FasL	_	ADJ	_	Number=Sing	_	_	_	_
4	interaction	_	NOUN	_	Number=Sing	_	_	_	_
5	initiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	death	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	many	_	ADJ	_	Degree=Pos	_	_	_	_
10	other	_	ADJ	_	Degree=Pos	_	_	_	_
11	systems	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	dysregulation	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	several	_	ADJ	_	Degree=Pos	_	_	_	_
22	pathologic	_	ADJ	_	Degree=Pos	_	_	_	_
23	conditions	_	NOUN	_	Number=Plur	_	_	_	_
24	arise	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Understanding	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	FasL	_	ADJ	_	Degree=Pos	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	could	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	very	_	ADV	_	_	_	_	_	_
11	useful	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	SCONJ	_	_	_	_	_	_
13	elucidating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	how	_	ADV	_	PronType=Int	_	_	_	_
15	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
16	diseases	_	NOUN	_	Number=Plur	_	_	_	_
17	develop	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	in	_	SCONJ	_	_	_	_	_	_
20	identifying	_	VERB	_	VerbForm=Ger	_	_	_	_
21	potential	_	ADJ	_	Degree=Pos	_	_	_	_
22	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
23	targets	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002446	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	AT	_	ADP	_	_	_	_	_	_
6	signal	_	NOUN	_	Number=Sing	_	_	_	_
7	transduction	_	NOUN	_	Number=Sing	_	_	_	_
8	events	_	NOUN	_	Number=Plur	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	negative	_	ADJ	_	Degree=Pos	_	_	_	_
14	form	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	"	_	PUNCT	_	_	_	_	_	_
5	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	negative	_	ADJ	_	Degree=Pos	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	"	_	PUNCT	_	_	_	_	_	_
10	form	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
14	catalytic	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	A	_	X	_	_	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	subunit	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	prepared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Int	_	_	_	_
23	lacks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	calmodulin	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	binding	_	VERB	_	Number=Sing	_	_	_	_
28	domain	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	autoinhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
31	domain	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	most	_	ADJ	_	Degree=Sup	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
36	catalytic	_	ADJ	_	Degree=Pos	_	_	_	_
37	core	_	NOUN	_	Number=Sing	_	_	_	_
38	but	_	CCONJ	_	_	_	_	_	_
39	possesses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	regulatory	_	ADJ	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	B	_	X	_	_	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	subunit	_	NOUN	_	Number=Sing	_	_	_	_
46	binding	_	VERB	_	Number=Sing	_	_	_	_
47	domain	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
5	ability	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	block	_	VERB	_	VerbForm=Inf	_	_	_	_
8	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	signaling	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	"	_	PUNCT	_	_	_	_	_	_
20	B	_	ADJ	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	subunit	_	NOUN	_	Number=Sing	_	_	_	_
23	knock	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	out	_	NOUN	_	Number=Sing	_	_	_	_
26	"	_	PUNCT	_	_	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	BKO	_	PROPN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	construct	_	VERB	_	VerbForm=Inf	_	_	_	_
31	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	reporter	_	NOUN	_	Number=Sing	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	activity	_	NOUN	_	Number=Sing	_	_	_	_
35	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	AT	_	ADP	_	_	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	pivotal	_	ADJ	_	Degree=Pos	_	_	_	_
43	promoter	_	NOUN	_	Number=Sing	_	_	_	_
44	element	_	NOUN	_	Number=Sing	_	_	_	_
45	for	_	ADP	_	_	_	_	_	_
46	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	IL	_	PROPN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	2	_	NUM	_	NumType=Card	_	_	_	_
52	gene	_	NOUN	_	Number=Sing	_	_	_	_
53	induction	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	epitope	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	labeled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	BKO	_	PROPN	_	Number=Sing	_	_	_	_
7	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	formation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	tight	_	ADJ	_	Degree=Pos	_	_	_	_
14	complex	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	subunit	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
27	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	sequestration	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	subunit	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	sharply	_	ADV	_	_	_	_	_	_
5	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	AT	_	ADP	_	_	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	co	_	X	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	transfecting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	BKO	_	PROPN	_	Number=Sing	_	_	_	_
16	could	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	"	_	PUNCT	_	_	_	_	_	_
19	rescued	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	"	_	PUNCT	_	_	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	subunit	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	depletion	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	subunit	_	NOUN	_	Number=Sing	_	_	_	_
34	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
35	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	potential	_	ADJ	_	Degree=Pos	_	_	_	_
6	utility	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	agents	_	NOUN	_	Number=Plur	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	disrupt	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	mediated	_	VERB	_	Degree=Pos	_	_	_	_
14	signal	_	NOUN	_	Number=Sing	_	_	_	_
15	transduction	_	NOUN	_	Number=Sing	_	_	_	_
16	pathways	_	NOUN	_	Number=Plur	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
19	formation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	catalytically	_	ADV	_	_	_	_	_	_
23	active	_	ADJ	_	Degree=Pos	_	_	_	_
24	dimer	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
27	A	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	B	_	ADJ	_	Number=Sing	_	_	_	_
30	subunits	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002447	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Rel	_	ADV	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
4	T	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	exhibit	_	NOUN	_	Number=Sing	_	_	_	_
7	defects	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
17	colony	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
3	protooncogene	_	NOUN	_	Number=Sing	_	_	_	_
4	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	subunit	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	like	_	ADJ	_	Degree=Pos	_	_	_	_
15	family	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Mice	_	NOUN	_	Number=Plur	_	_	_	_
2	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
3	Rel	_	NOUN	_	Number=Sing	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	defective	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	display	_	VERB	_	Number=Sing	_	_	_	_
16	impaired	_	VERB	_	Degree=Pos	_	_	_	_
17	humoral	_	ADJ	_	Degree=Pos	_	_	_	_
18	immunity	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	attempt	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
6	changes	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	accompany	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
14	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
15	defects	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	loss	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	Rel	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
24	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	surface	_	NOUN	_	Number=Sing	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	markers	_	NOUN	_	Number=Plur	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
35	production	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	Rel	_	NOUN	_	Number=Sing	_	_	_	_
41	-/-	_	PUNCT	_	_	_	_	_	_
42	T	_	NOUN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	surface	_	NOUN	_	Number=Sing	_	_	_	_
6	markers	_	NOUN	_	Number=Plur	_	_	_	_
7	including	_	VERB	_	VerbForm=Ger	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2R	_	NUM	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	chain	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	CD25	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	CD69	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	L	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	selectin	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	CD62	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	normal	_	ADJ	_	Degree=Pos	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	activated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
38	Rel	_	NOUN	_	Number=Sing	_	_	_	_
39	-/-	_	PUNCT	_	_	_	_	_	_
40	T	_	NOUN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	but	_	CCONJ	_	_	_	_	_	_
44	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
45	production	_	NOUN	_	Number=Sing	_	_	_	_
46	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
47	impaired	_	VERB	_	Degree=Pos	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	Rel	_	NOUN	_	Number=Sing	_	_	_	_
3	-/-	_	PUNCT	_	_	_	_	_	_
4	splenic	_	ADJ	_	Number=Sing	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	cultures	_	NOUN	_	Number=Plur	_	_	_	_
8	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
11	12	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	myristate	_	NOUN	_	Number=Sing	_	_	_	_
14	13	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	acetate	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	levels	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	3	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	5	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
34	colony	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
37	factor	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	GM	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	CSF	_	PROPN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	tumor	_	NOUN	_	Number=Sing	_	_	_	_
45	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
46	factor	_	NOUN	_	Number=Sing	_	_	_	_
47	alpha	_	NOUN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	TNF	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	alpha	_	NOUN	_	Number=Sing	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	and	_	CCONJ	_	_	_	_	_	_
55	gamma	_	NOUN	_	Number=Sing	_	_	_	_
56	interferon	_	NOUN	_	Number=Sing	_	_	_	_
57	(	_	PUNCT	_	_	_	_	_	_
58	IFN	_	PROPN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	gamma	_	NOUN	_	Number=Sing	_	_	_	_
61	)	_	PUNCT	_	_	_	_	_	_
62	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
63	only	_	ADV	_	_	_	_	_	_
64	2	_	NUM	_	NumType=Card	_	_	_	_
65	-	_	PUNCT	_	_	_	_	_	_
66	to	_	ADP	_	_	_	_	_	_
67	3	_	NUM	_	NumType=Card	_	_	_	_
68	-	_	PUNCT	_	_	_	_	_	_
69	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
70	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
71	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
72	with	_	ADP	_	_	_	_	_	_
73	normal	_	ADJ	_	Degree=Pos	_	_	_	_
74	T	_	NOUN	_	Number=Sing	_	_	_	_
75	cells	_	NOUN	_	Number=Plur	_	_	_	_
76	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	anti-CD3	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	anti-CD28	_	ADJ	_	Number=Sing	_	_	_	_
7	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	Rel	_	NOUN	_	Number=Sing	_	_	_	_
9	-/-	_	PUNCT	_	_	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	fail	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	proliferate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	make	_	VERB	_	VerbForm=Inf	_	_	_	_
19	little	_	ADJ	_	Degree=Pos	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	no	_	DET	_	_	_	_	_	_
22	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
23	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	restitutes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	anti-CD3	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	anti-CD28	_	ADJ	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	Rel	_	NOUN	_	Number=Sing	_	_	_	_
20	-/-	_	PUNCT	_	_	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	restores	_	NOUN	_	Number=Plur	_	_	_	_
25	production	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	5	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	TNF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	IFN	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	gamma	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	but	_	CCONJ	_	_	_	_	_	_
41	not	_	ADV	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	3	_	NUM	_	NumType=Card	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	GM	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	CSF	_	PROPN	_	Number=Sing	_	_	_	_
49	expression	_	NOUN	_	Number=Sing	_	_	_	_
50	to	_	PART	_	_	_	_	_	_
51	approximately	_	ADV	_	_	_	_	_	_
52	normal	_	ADJ	_	Degree=Pos	_	_	_	_
53	levels	_	NOUN	_	Number=Plur	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	mitogen	_	VERB	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	Rel	_	NOUN	_	Number=Sing	_	_	_	_
8	-/-	_	PUNCT	_	_	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	Rel	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	/-	_	PUNCT	_	_	_	_	_	_
18	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
19	produce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
21	than	_	ADP	_	_	_	_	_	_
22	normal	_	ADJ	_	Degree=Pos	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	GM	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	CSF	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	establish	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Rel	_	NOUN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	function	_	VERB	_	VerbForm=Inf	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	activator	_	NOUN	_	Number=Sing	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	repressor	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	3	_	NUM	_	NumType=Card	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	GM	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	CSF	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002451	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Ligand	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	repression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	GATA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	estrogen	_	NOUN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	High	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dose	_	NOUN	_	Number=Sing	_	_	_	_
4	estrogen	_	NOUN	_	Number=Sing	_	_	_	_
5	administration	_	NOUN	_	Number=Sing	_	_	_	_
6	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	anemia	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	mammals	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	chickens	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	estrogens	_	NOUN	_	Number=Plur	_	_	_	_
5	stimulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	outgrowth	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	bone	_	NOUN	_	Number=Sing	_	_	_	_
9	marrow	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
13	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	delay	_	VERB	_	VerbForm=Inf	_	_	_	_
17	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	maturation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	delay	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	down	_	ADP	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	many	_	ADJ	_	Degree=Pos	_	_	_	_
11	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	including	_	VERB	_	VerbForm=Ger	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	beta-globin	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	band	_	NOUN	_	Number=Sing	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	band	_	NOUN	_	Number=Sing	_	_	_	_
27	4.1	_	NUM	_	NumType=Card	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	specific	_	ADJ	_	Degree=Pos	_	_	_	_
35	histone	_	NOUN	_	Number=Sing	_	_	_	_
36	H5	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	estrogens	_	NOUN	_	Number=Plur	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	reduce	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	number	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
12	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	primary	_	ADJ	_	Degree=Pos	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	bone	_	NOUN	_	Number=Sing	_	_	_	_
18	marrow	_	NOUN	_	Degree=Pos	_	_	_	_
19	cultures	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	address	_	VERB	_	VerbForm=Inf	_	_	_	_
3	potential	_	ADJ	_	Degree=Pos	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	which	_	DET	_	PronType=Int	_	_	_	_
7	estrogens	_	NOUN	_	Number=Plur	_	_	_	_
8	suppress	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	erythropoiesis	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	effects	_	NOUN	_	Number=Plur	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	GATA	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	participates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	regulation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	majority	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	specific	_	ADJ	_	Degree=Pos	_	_	_	_
38	genes	_	NOUN	_	Number=Plur	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
42	for	_	ADP	_	_	_	_	_	_
43	full	_	ADJ	_	Degree=Pos	_	_	_	_
44	maturation	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	erythrocytes	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	GATA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	strongly	_	ADV	_	_	_	_	_	_
13	repressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	estrogen	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	ER	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	ligand	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	manner	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	repression	_	NOUN	_	Number=Sing	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	reversible	_	ADJ	_	Degree=Pos	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	presence	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	4	_	NUM	_	NumType=Card	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	hydroxytamoxifen	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	ER	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	VERB	_	Degree=Pos	_	_	_	_
4	repression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	GATA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	artificial	_	ADJ	_	Degree=Pos	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	single	_	ADJ	_	Degree=Pos	_	_	_	_
18	GATA	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	as	_	ADV	_	_	_	_	_	_
24	well	_	ADV	_	Degree=Pos	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	context	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	intact	_	NOUN	_	Number=Sing	_	_	_	_
32	promoter	_	NOUN	_	Number=Sing	_	_	_	_
33	which	_	PRON	_	PronType=Rel	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	normally	_	ADV	_	_	_	_	_	_
36	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	GATA	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	GATA	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	ER	_	NOUN	_	Number=Sing	_	_	_	_
6	bind	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	each	_	DET	_	_	_	_	_	_
9	other	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	vitro	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	absence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	coimmunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	using	_	VERB	_	VerbForm=Ger	_	_	_	_
5	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	COS	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	GATA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	ER	_	NOUN	_	Number=Sing	_	_	_	_
14	associate	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	ligand	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	manner	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Mapping	_	NOUN	_	Number=Sing	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	GATA	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	ER	_	NOUN	_	Number=Sing	_	_	_	_
11	form	_	NOUN	_	Number=Sing	_	_	_	_
12	at	_	ADV	_	_	_	_	_	_
13	least	_	ADV	_	Degree=Sup	_	_	_	_
14	two	_	NUM	_	NumType=Card	_	_	_	_
15	contacts	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	involve	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	finger	_	NOUN	_	Number=Sing	_	_	_	_
21	region	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	N	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	terminal	_	ADJ	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	domain	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	GATA	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	speculate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	estrogens	_	NOUN	_	Number=Plur	_	_	_	_
5	exert	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	erythropoiesis	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	SCONJ	_	_	_	_	_	_
10	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	GATA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	interaction	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	ER	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	003002452	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Anti-CD2	_	PROPN	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
4	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	HIV	_	PROPN	_	Number=Sing	_	_	_	_
7	long	_	ADJ	_	Degree=Pos	_	_	_	_
8	terminal	_	NOUN	_	Number=Sing	_	_	_	_
9	repeat	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CD2	_	PROPN	_	Number=Sing	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
5	glycoprotein	_	NOUN	_	Degree=Pos	_	_	_	_
6	surface	_	NOUN	_	Number=Sing	_	_	_	_
7	molecule	_	NOUN	_	Number=Sing	_	_	_	_
8	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	two	_	NUM	_	NumType=Card	_	_	_	_
20	processes	_	NOUN	_	Number=Plur	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	involved	_	ADJ	_	Degree=Pos	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	spread	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	HIV	_	NOUN	_	Number=Sing	_	_	_	_
29	infection	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	chronically	_	ADV	_	_	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	anti-CD2	_	PROPN	_	Degree=Pos	_	_	_	_
10	mAb	_	NOUN	_	Number=Sing	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	infectious	_	ADJ	_	Degree=Pos	_	_	_	_
20	virus	_	NOUN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
23	cultures	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	whereby	_	ADV	_	_	_	_	_	_
9	anti-CD2	_	ADJ	_	Degree=Pos	_	_	_	_
10	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
11	stimulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	viral	_	ADJ	_	Degree=Pos	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	transiently	_	ADV	_	_	_	_	_	_
7	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	anti-CD2	_	ADJ	_	Degree=Pos	_	_	_	_
12	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
13	results	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	HIV	_	PROPN	_	Number=Sing	_	_	_	_
19	long	_	ADJ	_	Degree=Pos	_	_	_	_
20	terminal	_	NOUN	_	Number=Sing	_	_	_	_
21	repeat	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CAT	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	using	_	VERB	_	VerbForm=Ger	_	_	_	_
6	mutated	_	VERB	_	Degree=Pos	_	_	_	_
7	HIV	_	PROPN	_	Number=Sing	_	_	_	_
8	long	_	ADJ	_	Degree=Pos	_	_	_	_
9	terminal	_	NOUN	_	Number=Sing	_	_	_	_
10	repeat	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	CAT	_	NOUN	_	Number=Sing	_	_	_	_
13	constructs	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	gel	_	NOUN	_	Number=Sing	_	_	_	_
16	shift	_	NOUN	_	Number=Sing	_	_	_	_
17	assays	_	NOUN	_	Number=Plur	_	_	_	_
18	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	DET	_	_	_	_	_	_
5	interaction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CD2	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	natural	_	ADJ	_	Degree=Pos	_	_	_	_
11	ligand	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	LFA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	3	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	play	_	VERB	_	VerbForm=Inf	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	role	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	regulation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	HIV	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002459	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Defective	_	ADJ	_	Degree=Pos	_	_	_	_
2	translocation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	C	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	multidrug	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
11	HL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	60	_	NUM	_	NumType=Card	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	reversible	_	ADJ	_	Degree=Pos	_	_	_	_
18	loss	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
21	ester	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	HL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	60	_	NUM	_	NumType=Card	_	_	_	_
10	myeloid	_	NUM	_	Degree=Pos	_	_	_	_
11	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	differentiate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
18	esters	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	event	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	c	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	jun	_	NOUN	_	Number=Sing	_	_	_	_
12	early	_	ADJ	_	Degree=Pos	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	appearance	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
20	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	vincristine	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	multidrug	_	ADJ	_	Degree=Pos	_	_	_	_
14	resistance	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	13	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	acetate	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	TPA	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	HL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	60	_	NUM	_	NumType=Card	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	multidrug	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
8	HL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	60	_	NUM	_	NumType=Card	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	HL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	60	_	NUM	_	NumType=Card	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	vinc	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	fail	_	VERB	_	Number=Sing	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	TPA	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	increase	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	c	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	jun	_	NOUN	_	Number=Sing	_	_	_	_
32	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	other	_	ADJ	_	Degree=Pos	_	_	_	_
35	phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
36	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
39	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	HL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	60	_	NUM	_	NumType=Card	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	vinc	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
14	acid	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	serine	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	threonine	_	NOUN	_	Number=Sing	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	c	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	jun	_	NOUN	_	Number=Sing	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	growth	_	NOUN	_	Number=Sing	_	_	_	_
32	arrest	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	c-fms	_	NOUN	_	Number=Plur	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	HL	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	60	_	NUM	_	NumType=Card	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	vinc	_	NOUN	_	Number=Sing	_	_	_	_
12	revertant	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	HL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	60	_	NUM	_	NumType=Card	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	vinc	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	R	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	line	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	regained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	partial	_	ADJ	_	Degree=Pos	_	_	_	_
27	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	vincristine	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	finding	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	SCONJ	_	PronType=Rel	_	_	_	_
4	HL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	60	_	NUM	_	NumType=Card	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	vinc	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	R	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	respond	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	TPA	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
20	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	not	_	ADV	_	_	_	_	_	_
24	c-jun	_	NOUN	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
30	induction	_	NOUN	_	Number=Sing	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	not	_	PART	_	_	_	_	_	_
33	obligatory	_	ADJ	_	Degree=Pos	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
36	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Other	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	further	_	ADV	_	_	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	jun	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	fra	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	TPA	_	PROPN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	HL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	60	_	NUM	_	NumType=Card	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	vinc	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	HL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	60/vinc/R	_	ADJ	_	NumType=Card	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	whereas	_	SCONJ	_	_	_	_	_	_
33	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	attenuated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	HL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	60	_	NUM	_	NumType=Card	_	_	_	_
42	/	_	PUNCT	_	_	_	_	_	_
43	vinc	_	NOUN	_	Number=Sing	_	_	_	_
44	line	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	TPA	_	PROPN	_	Number=Sing	_	_	_	_
3	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	C	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	PKC	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	translocation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	PKC	_	NOUN	_	Number=Sing	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	membrane	_	ADJ	_	Number=Sing	_	_	_	_
22	fraction	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	HL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	60	_	NUM	_	NumType=Card	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	HL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	60	_	NUM	_	NumType=Card	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	vinc/R	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	translocation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	PKC	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	subcellular	_	ADJ	_	Degree=Pos	_	_	_	_
20	redistribution	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	undetectable	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	HL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	60	_	NUM	_	NumType=Card	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	vinc	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Activity	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	family	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	associated	_	VERB	_	Degree=Pos	_	_	_	_
12	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
15	Y	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	peptide	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	markedly	_	ADV	_	_	_	_	_	_
20	diminished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	TPA	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	HL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	60	_	NUM	_	NumType=Card	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	vinc	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	but	_	CCONJ	_	_	_	_	_	_
33	not	_	PART	_	_	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	response	_	NOUN	_	Number=Sing	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
38	acid	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	findings	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	vincristine	_	ADJ	_	Degree=Pos	_	_	_	_
9	resistance	_	NOUN	_	Number=Sing	_	_	_	_
10	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	insensitivity	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	TPA	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	can	_	AUX	_	VerbForm=Fin	_	_	_	_
19	include	_	VERB	_	VerbForm=Inf	_	_	_	_
20	defects	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	PKC	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	signaling	_	VERB	_	Number=Sing	_	_	_	_
26	events	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	induction	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	jun	_	NOUN	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	fos	_	ADP	_	_	_	_	_	_
33	early	_	ADJ	_	Degree=Pos	_	_	_	_
34	response	_	NOUN	_	Number=Sing	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002466	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	HMG	_	INTJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	GATA	_	PROPN	_	Number=Sing	_	_	_	_
7	motifs	_	NOUN	_	Number=Plur	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	implications	_	NOUN	_	Number=Plur	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	HPFH	_	ADJ	_	Number=Sing	_	_	_	_
13	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	HMG	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	gamma	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	globin	_	NOUN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	HMG	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	preferentially	_	ADV	_	_	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	more	_	ADV	_	_	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	'	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	pair	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	GATA	_	NOUN	_	Number=Sing	_	_	_	_
19	motifs	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	gamma	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	globin	_	NOUN	_	Number=Sing	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	;	_	PUNCT	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	paired	_	VERB	_	Degree=Pos	_	_	_	_
29	motif	_	NOUN	_	Number=Sing	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	bound	_	ADJ	_	Degree=Pos	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	GATA	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	naturally	_	ADV	_	_	_	_	_	_
3	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
4	mutation	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	-	_	SYM	_	_	_	_	_	_
7	175	_	NUM	_	NumType=Card	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	C	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	area	_	NOUN	_	Number=Sing	_	_	_	_
15	bound	_	VERB	_	Degree=Pos	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	HMG	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
20	results	_	VERB	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	gamma	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	globin	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	adult	_	NOUN	_	Number=Sing	_	_	_	_
29	red	_	ADJ	_	Degree=Pos	_	_	_	_
30	blood	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	HPFH	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	up	_	ADP	_	_	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	regulation	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	gamma	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	globin	_	NOUN	_	Number=Sing	_	_	_	_
44	promoter	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	vitro	_	ADJ	_	Number=Sing	_	_	_	_
48	expression	_	NOUN	_	Number=Sing	_	_	_	_
49	assays	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
50	;	_	PUNCT	_	_	_	_	_	_
51	HMG	_	INTJ	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
54	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
55	not	_	PART	_	_	_	_	_	_
56	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
57	to	_	ADP	_	_	_	_	_	_
58	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
59	mutant	_	ADJ	_	Number=Sing	_	_	_	_
60	sequence	_	NOUN	_	Number=Sing	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	survey	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	GATA	_	NOUN	_	Number=Sing	_	_	_	_
5	motifs	_	NOUN	_	Number=Plur	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	other	_	ADJ	_	Degree=Pos	_	_	_	_
8	globin	_	ADJ	_	Degree=Pos	_	_	_	_
9	cis	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	elements	_	NOUN	_	Number=Plur	_	_	_	_
12	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	HMG	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	binding	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	most	_	ADJ	_	Degree=Sup	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	implicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	HMG	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	HPFH	_	ADJ	_	Number=Sing	_	_	_	_
10	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
11	;	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	speculate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	formation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	multiprotein	_	ADJ	_	Number=Sing	_	_	_	_
23	complexes	_	NOUN	_	Number=Plur	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	globin	_	ADJ	_	Degree=Pos	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002468	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	nongenomic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
8	immunosuppression	_	NOUN	_	Number=Sing	_	_	_	_
9	:	_	PUNCT	_	_	_	_	_	_
10	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	K	_	NUM	_	Number=Sing	_	_	_	_
13	+	_	SYM	_	_	_	_	_	_
14	channels	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
17	+	_	SYM	_	_	_	_	_	_
18	signaling	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	T	_	PROPN	_	Number=Sing	_	_	_	_
25	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
6	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	localized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	suppression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	immune	_	ADJ	_	Degree=Pos	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	during	_	ADP	_	_	_	_	_	_
14	pregnancy	_	NOUN	_	Number=Sing	_	_	_	_
15	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	remained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	elusive	_	ADJ	_	Degree=Pos	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
17	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	placenta	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	rapidly	_	ADV	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	reversibly	_	ADV	_	_	_	_	_	_
25	blocks	_	NOUN	_	Number=Plur	_	_	_	_
26	voltage	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	gated	_	ADJ	_	Degree=Pos	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	calcium	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	K+	_	NOUN	_	Number=Sing	_	_	_	_
34	channels	_	NOUN	_	Number=Plur	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	KV	_	PROPN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	KCa	_	PROPN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	respectively	_	ADV	_	_	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	depolarization	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	membrane	_	ADJ	_	Number=Sing	_	_	_	_
49	potential	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	result	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
6	+	_	SYM	_	_	_	_	_	_
7	signaling	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	AT	_	ADP	_	_	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Progesterone	_	PROPN	_	Number=Sing	_	_	_	_
2	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	distally	_	ADV	_	_	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	initial	_	ADJ	_	Degree=Pos	_	_	_	_
7	steps	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	TCR	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
17	signal	_	NOUN	_	Number=Sing	_	_	_	_
18	transduction	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	since	_	SCONJ	_	_	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	blocks	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
25	+	_	SYM	_	_	_	_	_	_
26	signals	_	NOUN	_	Number=Plur	_	_	_	_
27	after	_	ADP	_	_	_	_	_	_
28	thapsigargin	_	NOUN	_	Number=Sing	_	_	_	_
29	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	as	_	ADV	_	_	_	_	_	_
32	well	_	ADV	_	Degree=Pos	_	_	_	_
33	as	_	ADP	_	_	_	_	_	_
34	oscillatory	_	ADJ	_	Degree=Pos	_	_	_	_
35	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
36	+	_	SYM	_	_	_	_	_	_
37	signals	_	NOUN	_	Number=Plur	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	but	_	CCONJ	_	_	_	_	_	_
40	not	_	ADV	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
43	+	_	SYM	_	_	_	_	_	_
44	transient	_	NOUN	_	Number=Sing	_	_	_	_
45	after	_	ADP	_	_	_	_	_	_
46	TCR	_	NOUN	_	Number=Sing	_	_	_	_
47	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	K	_	PROPN	_	Number=Sing	_	_	_	_
2	+	_	SYM	_	_	_	_	_	_
3	channel	_	NOUN	_	Number=Sing	_	_	_	_
4	blockade	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	;	_	PUNCT	_	_	_	_	_	_
10	other	_	ADJ	_	Degree=Pos	_	_	_	_
11	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
12	hormones	_	NOUN	_	Number=Plur	_	_	_	_
13	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	little	_	ADJ	_	Degree=Pos	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	no	_	DET	_	_	_	_	_	_
17	effect	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	although	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
22	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
23	RU	_	PROPN	_	Number=Sing	_	_	_	_
24	486	_	NUM	_	NumType=Card	_	_	_	_
25	also	_	ADV	_	_	_	_	_	_
26	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	KV	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	KCa	_	PROPN	_	Number=Sing	_	_	_	_
30	channels	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Progesterone	_	NOUN	_	Number=Sing	_	_	_	_
2	effectively	_	ADV	_	_	_	_	_	_
3	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	broad	_	ADJ	_	Degree=Pos	_	_	_	_
6	spectrum	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	K	_	NUM	_	Number=Sing	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_
10	channels	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	reducing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	Kv1.3	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	charybdotoxin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
19	components	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	KV	_	PROPN	_	Number=Sing	_	_	_	_
22	current	_	ADJ	_	Degree=Pos	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	KCa	_	PROPN	_	Number=Sing	_	_	_	_
25	current	_	ADJ	_	Degree=Pos	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	T	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	as	_	ADV	_	_	_	_	_	_
31	well	_	ADV	_	Degree=Pos	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
34	several	_	ADJ	_	Degree=Pos	_	_	_	_
35	cloned	_	ADJ	_	Degree=Pos	_	_	_	_
36	KV	_	NOUN	_	Number=Sing	_	_	_	_
37	channels	_	NOUN	_	Number=Plur	_	_	_	_
38	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	lines	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Progesterone	_	PROPN	_	Number=Sing	_	_	_	_
2	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	little	_	ADJ	_	Degree=Pos	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	no	_	DET	_	_	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	cloned	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
10	voltage	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	gated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	Na	_	PROPN	_	Number=Sing	_	_	_	_
14	+	_	SYM	_	_	_	_	_	_
15	channel	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	inward	_	ADJ	_	Degree=Pos	_	_	_	_
19	rectifier	_	NOUN	_	Number=Sing	_	_	_	_
20	K	_	PROPN	_	Number=Sing	_	_	_	_
21	+	_	SYM	_	_	_	_	_	_
22	channel	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
27	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
28	+	_	SYM	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	Cl	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	channels	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	DET	_	_	_	_	_	_
4	direct	_	ADJ	_	Degree=Pos	_	_	_	_
5	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	K	_	NUM	_	Number=Sing	_	_	_	_
8	+	_	SYM	_	_	_	_	_	_
9	channels	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
15	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	immunosuppression	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002472	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Involvement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Rel	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	Fos	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Jun	_	PROPN	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	CD28	_	PROPN	_	Number=Sing	_	_	_	_
20	response	_	NOUN	_	Number=Sing	_	_	_	_
21	element	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	AP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	sequence	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	T	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	CD28	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	important	_	ADJ	_	Degree=Pos	_	_	_	_
5	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	molecule	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Costimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	through	_	ADP	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	Ag	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	CD28	_	PROPN	_	Number=Sing	_	_	_	_
12	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	high	_	ADJ	_	Degree=Pos	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	production	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	vital	_	ADJ	_	Degree=Pos	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	development	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	immune	_	ADJ	_	Degree=Pos	_	_	_	_
30	response	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	vivo	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	reports	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	CD28	_	PROPN	_	Number=Sing	_	_	_	_
7	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
8	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	up	_	ADV	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	several	_	ADJ	_	Degree=Pos	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	factors	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	including	_	VERB	_	VerbForm=Ger	_	_	_	_
30	AP	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	/	_	PUNCT	_	_	_	_	_	_
44	Rel	_	NOUN	_	Number=Sing	_	_	_	_
45	family	_	NOUN	_	Number=Sing	_	_	_	_
46	members	_	NOUN	_	Number=Plur	_	_	_	_
47	as	_	ADV	_	_	_	_	_	_
48	well	_	ADV	_	Degree=Pos	_	_	_	_
49	as	_	ADP	_	_	_	_	_	_
50	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
51	uncharacterized	_	ADJ	_	Degree=Pos	_	_	_	_
52	transcription	_	NOUN	_	Number=Sing	_	_	_	_
53	factor	_	NOUN	_	Number=Sing	_	_	_	_
54	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
55	CD28	_	PROPN	_	Number=Sing	_	_	_	_
56	response	_	NOUN	_	Number=Sing	_	_	_	_
57	complex	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	several	_	ADJ	_	Degree=Pos	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	investigation	_	NOUN	_	Number=Sing	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	Rel	_	PROPN	_	Number=Sing	_	_	_	_
14	family	_	NOUN	_	Number=Sing	_	_	_	_
15	members	_	NOUN	_	Number=Plur	_	_	_	_
16	make	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	up	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	CD28	_	PROPN	_	Number=Sing	_	_	_	_
20	response	_	NOUN	_	Number=Sing	_	_	_	_
21	complex	_	NOUN	_	Degree=Pos	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	other	_	ADJ	_	Degree=Pos	_	_	_	_
26	work	_	NOUN	_	Number=Sing	_	_	_	_
27	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	supported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	CD28	_	PROPN	_	Number=Sing	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	element	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	CD28RE	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	function	_	VERB	_	VerbForm=Inf	_	_	_	_
15	independently	_	ADV	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	works	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	instead	_	ADV	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	conjunction	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	proximal	_	ADJ	_	Number=Sing	_	_	_	_
26	AP	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
34	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
35	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	here	_	ADV	_	PronType=Dem	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Also	_	ADV	_	_	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	current	_	ADJ	_	Degree=Pos	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	CD28RE	_	PROPN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	sequence	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	four	_	NUM	_	NumType=Card	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	complexes	_	NOUN	_	Number=Plur	_	_	_	_
5	can	_	AUX	_	VerbForm=Fin	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	only	_	ADV	_	_	_	_	_	_
14	one	_	NUM	_	NumType=Card	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
17	complexes	_	NOUN	_	Number=Plur	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	both	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	CD28RE	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
27	AP	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	site	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Of	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	Rel	_	PROPN	_	Number=Sing	_	_	_	_
8	family	_	NOUN	_	Number=Sing	_	_	_	_
9	members	_	NOUN	_	Number=Plur	_	_	_	_
10	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	CD28RE	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	complex	_	NOUN	_	Number=Sing	_	_	_	_
21	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	predominantly	_	ADV	_	_	_	_	_	_
23	c-Rel	_	ADJ	_	Degree=Pos	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	despite	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	fact	_	NOUN	_	Number=Sing	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	both	_	DET	_	_	_	_	_	_
30	p50	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	RelA	_	PROPN	_	Number=Sing	_	_	_	_
33	can	_	AUX	_	VerbForm=Fin	_	_	_	_
34	efficiently	_	ADV	_	_	_	_	_	_
35	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	CD28RE	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	CD28RE	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1-specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	complex	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	functional	_	ADJ	_	Degree=Pos	_	_	_	_
6	complexes	_	NOUN	_	Number=Plur	_	_	_	_
7	encompassing	_	VERB	_	VerbForm=Ger	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	CD28RE	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	influence	_	NOUN	_	Number=Sing	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	CD28	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	costimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	T	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002482	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Monocyte	_	PROPN	_	Number=Sing	_	_	_	_
2	tethering	_	VERB	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	P	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	selectin	_	NOUN	_	Number=Sing	_	_	_	_
7	regulates	_	VERB	_	Number=Plur	_	_	_	_
8	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
9	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	tumor	_	NOUN	_	Number=Sing	_	_	_	_
15	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	secretion	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Signal	_	PROPN	_	Number=Sing	_	_	_	_
2	integration	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	translocation	_	NOUN	_	Number=Sing	_	_	_	_
9	[	_	PUNCT	_	_	_	_	_	_
10	see	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
11	comments	_	NOUN	_	Number=Plur	_	_	_	_
12	]	_	PUNCT	_	_	_	_	_	_

1	Adhesion	_	NOUN	_	Number=Sing	_	_	_	_
2	molecules	_	NOUN	_	Number=Plur	_	_	_	_
3	that	_	PRON	_	PronType=Rel	_	_	_	_
4	tether	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
6	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	endothelial	_	VERB	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	transduce	_	VERB	_	VerbForm=Inf	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
15	outside	_	ADV	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	signals	_	NOUN	_	Number=Plur	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	providing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	initial	_	ADJ	_	Degree=Pos	_	_	_	_
26	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	point	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	response	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Adhesion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	P	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	selectin	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	most	_	ADV	_	_	_	_	_	_
12	rapidly	_	ADV	_	_	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
15	tethering	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	secretion	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
23	chemotactic	_	ADJ	_	Number=Sing	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	MCP	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	tumor	_	NOUN	_	Number=Sing	_	_	_	_
34	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	TNF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	alpha	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
46	when	_	ADV	_	PronType=Rel	_	_	_	_
47	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
48	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
49	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
50	with	_	ADP	_	_	_	_	_	_
51	platelet	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
54	factor	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
3	secretion	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	specifically	_	ADV	_	_	_	_	_	_
6	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	G1	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	anti-P	_	ADJ	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	selectin	_	NOUN	_	Number=Sing	_	_	_	_
14	mAb	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	P-	_	PUNCT	_	Number=Sing	_	_	_	_
18	selectin	_	NOUN	_	Number=Sing	_	_	_	_
19	from	_	SCONJ	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	ligand	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	P-	_	PUNCT	_	Number=Sing	_	_	_	_
26	selectin	_	VERB	_	Number=Sing	_	_	_	_
27	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
28	ligand	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	on	_	ADP	_	_	_	_	_	_
33	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	tethering	_	VERB	_	VerbForm=Ger	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	P	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	selectin	_	NOUN	_	Number=Sing	_	_	_	_
8	specifically	_	ADV	_	_	_	_	_	_
9	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	translocation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	MCP	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	TNF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	alpha	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	other	_	ADJ	_	Degree=Pos	_	_	_	_
42	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	early	_	ADJ	_	Degree=Pos	_	_	_	_
45	genes	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	P-	_	PUNCT	_	Number=Sing	_	_	_	_
6	selectin	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	ligands	_	NOUN	_	Number=Plur	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	locally	_	ADV	_	_	_	_	_	_
16	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
18	secretion	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	inflamed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	tissues	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002487	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Role	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
4	tumor	_	NOUN	_	Number=Sing	_	_	_	_
5	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
18	transformation	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
21	Saimiri	_	PROPN	_	Number=Sing	_	_	_	_
22	STP	_	PROPN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	STP	_	NOUN	_	Number=Sing	_	_	_	_
3	oncoproteins	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
7	saimiri	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HVS	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	subgroup	_	NOUN	_	Number=Sing	_	_	_	_
12	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	strain	_	NOUN	_	Number=Sing	_	_	_	_
14	11	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	subgroup	_	NOUN	_	Number=Sing	_	_	_	_
17	C	_	PROPN	_	Number=Sing	_	_	_	_
18	strain	_	NOUN	_	Number=Sing	_	_	_	_
19	488	_	NUM	_	NumType=Card	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	now	_	ADV	_	_	_	_	_	_
22	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	stably	_	ADV	_	_	_	_	_	_
26	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	tumor	_	NOUN	_	Number=Sing	_	_	_	_
29	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	receptor	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	factor	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	TRAF	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	2	_	NUM	_	NumType=Card	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	or	_	CCONJ	_	_	_	_	_	_
43	3	_	NUM	_	NumType=Card	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Mutational	_	ADJ	_	Degree=Pos	_	_	_	_
2	analyses	_	NOUN	_	Number=Plur	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	residues	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	PXQXT	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	S	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	STP	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	A11	_	NOUN	_	Number=Sing	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	critical	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	TRAF	_	PROPN	_	Number=Sing	_	_	_	_
17	association	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	somewhat	_	ADV	_	_	_	_	_	_
6	divergent	_	ADJ	_	Degree=Pos	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	STP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	C488	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	critical	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	TRAF	_	PROPN	_	Number=Sing	_	_	_	_
16	association	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Mutational	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	STP	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	C488	_	NOUN	_	Number=Sing	_	_	_	_
9	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	ability	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	associate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	TRAFs	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	HVS	_	PROPN	_	Number=Sing	_	_	_	_
3	STP	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	C488	_	NOUN	_	NumType=Card	_	_	_	_
6	P10	_	NUM	_	Number=Sing	_	_	_	_
7	-->R	_	NOUN	_	_	_	_	_	_
8	mutant	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	T-lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
14	transformation	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	interleukin	_	VERB	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	independent	_	ADJ	_	Degree=Pos	_	_	_	_
21	growth	_	NOUN	_	Number=Sing	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	wild	_	ADJ	_	Degree=Pos	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	type	_	NOUN	_	Number=Sing	_	_	_	_
27	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	marmoset	_	NOUN	_	Degree=Pos	_	_	_	_
30	T-lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
31	transformation	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	vitro	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	vivo	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	STP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	C488	_	NOUN	_	NumType=Card	_	_	_	_
5	P10	_	NUM	_	Number=Sing	_	_	_	_
6	-->R	_	NOUN	_	Number=Sing	_	_	_	_
7	mutant	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	defective	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	Rat	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	fibroblast	_	NOUN	_	Number=Sing	_	_	_	_
16	transformation	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	fibroblast	_	NOUN	_	Degree=Pos	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	transformation	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
27	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	negative	_	ADJ	_	Degree=Pos	_	_	_	_
30	mutant	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	implicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	TRAFs	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	STP	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	C488	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
11	transformation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	rodent	_	ADJ	_	Degree=Pos	_	_	_	_
17	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Other	_	ADJ	_	Degree=Pos	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	common	_	ADJ	_	Degree=Pos	_	_	_	_
9	marmoset	_	NOUN	_	Degree=Pos	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	critical	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	transformation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	rodent	_	ADJ	_	Degree=Pos	_	_	_	_
25	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002488	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Signal	_	ADJ	_	Number=Sing	_	_	_	_
2	transduction	_	NOUN	_	Number=Sing	_	_	_	_
3	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	patients	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	advanced	_	ADJ	_	Degree=Pos	_	_	_	_
11	renal	_	ADJ	_	Degree=Pos	_	_	_	_
12	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
15	relevance	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	effects	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
20	therapy	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	CD3	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
10	antigen	_	NOUN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	TCR	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	pathways	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	signal	_	ADJ	_	Number=Sing	_	_	_	_
19	transduction	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	animals	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	patients	_	NOUN	_	Number=Plur	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	advanced	_	ADJ	_	Degree=Pos	_	_	_	_
29	malignancy	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Diminished	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TCRzeta	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	p56	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	lck	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	TCR	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	localization	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	RelA	_	NOUN	_	Number=Sing	_	_	_	_
22	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	complexes	_	NOUN	_	Number=Plur	_	_	_	_
30	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
32	noted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	defects	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	patients	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
13	melanoma	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	renal	_	ADJ	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	RCC	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	ovarian	_	ADJ	_	Degree=Pos	_	_	_	_
23	cancer	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	colorectal	_	ADJ	_	Number=Sing	_	_	_	_
27	cancer	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Preliminary	_	ADJ	_	Degree=Pos	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	possible	_	ADJ	_	Degree=Pos	_	_	_	_
6	correlation	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
9	variables	_	NOUN	_	Number=Plur	_	_	_	_
10	such	_	ADJ	_	Degree=Pos	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	stage	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	instances	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	To	_	ADP	_	_	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
4	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	TCRzeta	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	p56	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	lck	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	impaired	_	VERB	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	65	_	NUM	_	NumType=Card	_	_	_	_
26	patients	_	NOUN	_	Number=Plur	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	RCC	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	majority	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	whom	_	PRON	_	PronType=Rel	_	_	_	_
34	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	receiving	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
36	combination	_	NOUN	_	Number=Sing	_	_	_	_
37	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
38	therapy	_	NOUN	_	Number=Sing	_	_	_	_
39	[	_	PUNCT	_	_	_	_	_	_
40	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	2	_	NUM	_	NumType=Card	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	IFN	_	PROPN	_	Number=Sing	_	_	_	_
48	alpha	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
51	regimens	_	NOUN	_	Number=Plur	_	_	_	_
52	]	_	PUNCT	_	_	_	_	_	_
53	and	_	CCONJ	_	_	_	_	_	_
54	37	_	NUM	_	NumType=Card	_	_	_	_
55	control	_	NOUN	_	Number=Sing	_	_	_	_
56	individuals	_	NOUN	_	Number=Plur	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	29	_	NUM	_	NumType=Card	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	patients	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	TCRzeta	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	p56(lck	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	Western	_	ADJ	_	Degree=Pos	_	_	_	_
17	blots	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
20	lysates	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	semiquantitated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	using	_	VERB	_	VerbForm=Ger	_	_	_	_
24	densitometry	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Relative	_	ADJ	_	Degree=Pos	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	then	_	ADV	_	PronType=Dem	_	_	_	_
5	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	series	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
11	variables	_	NOUN	_	Number=Plur	_	_	_	_
12	including	_	VERB	_	VerbForm=Ger	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	therapy	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	performance	_	NOUN	_	Number=Sing	_	_	_	_
18	status	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	survival	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	disease	_	NOUN	_	Number=Sing	_	_	_	_
23	sites	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	age	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	others	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	another	_	DET	_	_	_	_	_	_
3	group	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	28	_	NUM	_	NumType=Card	_	_	_	_
6	patients	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	three	_	NUM	_	NumType=Card	_	_	_	_
9	individuals	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
13	group	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	frequency	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
20	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	using	_	VERB	_	VerbForm=Ger	_	_	_	_
25	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
26	mobility	_	NOUN	_	Number=Sing	_	_	_	_
27	shift	_	NOUN	_	Number=Sing	_	_	_	_
28	assays	_	NOUN	_	Number=Plur	_	_	_	_
29	after	_	ADP	_	_	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	T	_	PROPN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
36	myristate	_	NOUN	_	Number=Sing	_	_	_	_
37	acetate	_	NOUN	_	Number=Sing	_	_	_	_
38	/	_	PUNCT	_	_	_	_	_	_
39	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
40	or	_	CCONJ	_	_	_	_	_	_
41	anti-CD3	_	ADJ	_	Number=Sing	_	_	_	_
42	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
43	antibody	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Changes	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	signaling	_	VERB	_	Degree=Pos	_	_	_	_
5	molecules	_	NOUN	_	Number=Plur	_	_	_	_
6	during	_	ADP	_	_	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	treatment	_	NOUN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	also	_	ADV	_	_	_	_	_	_
11	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	TCRzeta	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	p56	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	lck	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
12	blood	_	NOUN	_	Number=Sing	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	27	_	NUM	_	NumType=Card	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	29	_	NUM	_	NumType=Card	_	_	_	_
19	patients	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	overall	_	ADV	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	levels	_	NOUN	_	Number=Plur	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	noted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	visually	_	ADV	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	12	_	NUM	_	NumType=Card	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	29	_	NUM	_	NumType=Card	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	41	_	NUM	_	NumType=Card	_	_	_	_
35	%	_	SYM	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	13	_	NUM	_	NumType=Card	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	29	_	NUM	_	NumType=Card	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	45	_	NUM	_	NumType=Card	_	_	_	_
43	%	_	SYM	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	individuals	_	NOUN	_	Number=Plur	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	respectively	_	ADV	_	_	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	semiquantitated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	using	_	VERB	_	VerbForm=Ger	_	_	_	_
6	densitometry	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	significant	_	ADJ	_	Degree=Pos	_	_	_	_
9	decreases	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	TCRzeta	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	P	_	NOUN	_	Number=Sing	_	_	_	_
14	=	_	SYM	_	_	_	_	_	_
15	0.029	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	p56	_	NUM	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	lck	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	P	_	NOUN	_	Number=Sing	_	_	_	_
24	=	_	SYM	_	_	_	_	_	_
25	0.029	_	NUM	_	NumType=Card	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	not	_	ADV	_	_	_	_	_	_
29	CD3epsilon	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	P	_	NOUN	_	Number=Sing	_	_	_	_
32	=	_	SYM	_	_	_	_	_	_
33	0.131	_	NUM	_	NumType=Card	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	control	_	NOUN	_	Number=Sing	_	_	_	_
39	levels	_	NOUN	_	Number=Plur	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
42	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	patients	_	NOUN	_	Number=Sing	_	_	_	_
3	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2/IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	therapy	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	relative	_	ADJ	_	Degree=Pos	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	TCRzeta	_	PROPN	_	Number=Sing	_	_	_	_
17	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	significantly	_	ADV	_	_	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	P	_	NOUN	_	Number=Sing	_	_	_	_
21	=	_	SYM	_	_	_	_	_	_
22	0.002	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	day	_	NOUN	_	Number=Sing	_	_	_	_
26	15	_	NUM	_	NumType=Card	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	cycle	_	NOUN	_	Number=Sing	_	_	_	_
29	one	_	NUM	_	NumType=Card	_	_	_	_
30	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	baseline	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Correlations	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TCRzeta	_	NOUN	_	Number=Sing	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	p56	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	lck	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	disease	_	NOUN	_	Number=Sing	_	_	_	_
14	variables	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	except	_	ADP	_	_	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
19	TCRzeta	_	NOUN	_	Number=Sing	_	_	_	_
20	levels	_	NOUN	_	Number=Plur	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	P	_	NOUN	_	Number=Sing	_	_	_	_
23	<	_	PUNCT	_	_	_	_	_	_
24	0.001	_	NUM	_	NumType=Card	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	presence	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	bone	_	NOUN	_	Number=Sing	_	_	_	_
31	metastases	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
2	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	after	_	ADP	_	_	_	_	_	_
5	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
8	myristate	_	NOUN	_	Number=Sing	_	_	_	_
9	acetate	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	anti-CD3	_	ADJ	_	Number=Sing	_	_	_	_
16	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
17	antibody	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	59	_	NUM	_	NumType=Card	_	_	_	_
22	%	_	SYM	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	patients	_	NOUN	_	Number=Plur	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	17	_	NUM	_	NumType=Card	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	28	_	NUM	_	NumType=Card	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
32	not	_	PART	_	_	_	_	_	_
33	accounted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	advanced	_	ADJ	_	Degree=Pos	_	_	_	_
38	age	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	study	_	NOUN	_	Number=Sing	_	_	_	_
42	cohort	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
13	therapy	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	four	_	NUM	_	NumType=Card	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	six	_	NUM	_	NumType=Card	_	_	_	_
18	individuals	_	NOUN	_	Number=Plur	_	_	_	_
19	who	_	PRON	_	PronType=Rel	_	_	_	_
20	displayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	impaired	_	VERB	_	Degree=Pos	_	_	_	_
22	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	prior	_	ADJ	_	Degree=Pos	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	therapy	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
7	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	appear	_	VERB	_	VerbForm=Inf	_	_	_	_
10	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	reduction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	TCRzeta	_	PROPN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	because	_	SCONJ	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	five	_	NUM	_	NumType=Card	_	_	_	_
21	patients	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	normal	_	ADJ	_	Degree=Pos	_	_	_	_
24	TCRzeta	_	NOUN	_	Number=Sing	_	_	_	_
25	levels	_	NOUN	_	Number=Plur	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	present	_	ADJ	_	Degree=Pos	_	_	_	_
28	although	_	SCONJ	_	_	_	_	_	_
29	kappaB	_	ADJ	_	Number=Sing	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
32	not	_	PART	_	_	_	_	_	_
33	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	majority	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	patients	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	advanced	_	ADJ	_	Degree=Pos	_	_	_	_
8	RCC	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
11	blood	_	NOUN	_	Number=Sing	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	express	_	VERB	_	Degree=Pos	_	_	_	_
15	TCRzeta	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	p56	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	lck	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	subset	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	levels	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
31	TCRzeta	_	PROPN	_	Number=Sing	_	_	_	_
32	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	molecules	_	NOUN	_	Number=Plur	_	_	_	_
34	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	that	_	PRON	_	PronType=Dem	_	_	_	_
37	may	_	AUX	_	VerbForm=Fin	_	_	_	_
38	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
39	during	_	ADP	_	_	_	_	_	_
40	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	therapy	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	present	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	>	_	SYM	_	_	_	_	_	_
10	50	_	NUM	_	NumType=Card	_	_	_	_
11	%	_	SYM	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	patients	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	also	_	ADV	_	_	_	_	_	_
17	revert	_	VERB	_	VerbForm=Inf	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	normal	_	ADJ	_	Degree=Pos	_	_	_	_
20	during	_	ADP	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2/IFN	_	PROPN	_	Number=Sing	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	treatment	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	alteration	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	presence	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	normal	_	ADJ	_	Degree=Pos	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	TCRzeta	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	signaling	_	NOUN	_	Number=Sing	_	_	_	_
18	elements	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
3	significance	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	findings	_	NOUN	_	Number=Plur	_	_	_	_
7	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002493	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_
5	C	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	elevation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
10	interact	_	NOUN	_	Number=Sing	_	_	_	_
11	synergistically	_	ADV	_	_	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	raise	_	VERB	_	VerbForm=Inf	_	_	_	_
14	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	AP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	earlier	_	ADV	_	Degree=Cmp	_	_	_	_
4	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	C	_	PROPN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	PKC	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cyclic	_	ADJ	_	Number=Sing	_	_	_	_
20	adenosine	_	NOUN	_	Degree=Pos	_	_	_	_
21	monophosphate	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	adenosine	_	ADJ	_	Degree=Pos	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	Gs	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	therefore	_	ADV	_	_	_	_	_	_
5	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
11	ester	_	NOUN	_	Number=Sing	_	_	_	_
12	PMA	_	PROPN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
15	12	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	myristate	_	NOUN	_	Number=Sing	_	_	_	_
18	13	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	acetate	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	PKC	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	combination	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	adenosine	_	NOUN	_	Degree=Pos	_	_	_	_
31	receptor	_	NOUN	_	Number=Sing	_	_	_	_
32	agonist	_	NOUN	_	Number=Sing	_	_	_	_
33	NECA	_	PROPN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	5'-	_	NUM	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	N	_	CCONJ	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	ethyl	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	carboxamido	_	PROPN	_	Number=Sing	_	_	_	_
43	adenosine	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	forskolin	_	VERB	_	Number=Sing	_	_	_	_
47	to	_	PART	_	_	_	_	_	_
48	raise	_	VERB	_	VerbForm=Inf	_	_	_	_
49	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	on	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	levels	_	NOUN	_	Number=Plur	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	c	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	Fos	_	PROPN	_	Number=Sing	_	_	_	_
58	and	_	CCONJ	_	_	_	_	_	_
59	Jun	_	PROPN	_	Number=Sing	_	_	_	_
60	and	_	CCONJ	_	_	_	_	_	_
61	on	_	ADP	_	_	_	_	_	_
62	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
63	binding	_	NOUN	_	Number=Sing	_	_	_	_
64	and	_	CCONJ	_	_	_	_	_	_
65	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
66	activity	_	NOUN	_	Number=Sing	_	_	_	_
67	of	_	ADP	_	_	_	_	_	_
68	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
69	transcription	_	NOUN	_	Number=Sing	_	_	_	_
70	factor	_	NOUN	_	Number=Sing	_	_	_	_
71	,	_	PUNCT	_	_	_	_	_	_
72	activator	_	NOUN	_	Number=Sing	_	_	_	_
73	protein	_	NOUN	_	Number=Sing	_	_	_	_
74	-	_	PUNCT	_	_	_	_	_	_
75	1	_	NUM	_	NumType=Card	_	_	_	_
76	(	_	PUNCT	_	_	_	_	_	_
77	AP	_	NOUN	_	Number=Sing	_	_	_	_
78	-	_	PUNCT	_	_	_	_	_	_
79	1	_	NUM	_	NumType=Card	_	_	_	_
80	)	_	PUNCT	_	_	_	_	_	_
81	.	_	PUNCT	_	_	_	_	_	_

1	PMA	_	PROPN	_	Number=Sing	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	concentration	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	time	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	increase	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	c-Fos	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	Jun	_	PROPN	_	Number=Sing	_	_	_	_
17	immunoreactivity	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	contrast	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
22	elevation	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	only	_	ADV	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	slight	_	ADJ	_	Degree=Pos	_	_	_	_
28	effect	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	PMA	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	combination	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NECA	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	forskolin	_	PROPN	_	Number=Sing	_	_	_	_
10	acted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	together	_	ADV	_	_	_	_	_	_
12	either	_	ADV	_	_	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	c	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	Fos	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	decrease	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	Jun	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	levels	_	NOUN	_	Number=Plur	_	_	_	_
27	as	_	ADV	_	_	_	_	_	_
28	well	_	ADV	_	Degree=Pos	_	_	_	_
29	as	_	ADP	_	_	_	_	_	_
30	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
31	AP	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	binding	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	as	_	SCONJ	_	_	_	_	_	_
37	judged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	gel	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	shift	_	NOUN	_	Number=Sing	_	_	_	_
42	assay	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	AP	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
49	activity	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	there	_	PRON	_	_	_	_	_	_
3	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	clear	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	cut	_	NOUN	_	Number=Sing	_	_	_	_
8	synergy	_	NOUN	_	Number=Sing	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	PKC	_	PROPN	_	Number=Sing	_	_	_	_
12	stimulator	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
16	elevating	_	VERB	_	VerbForm=Ger	_	_	_	_
17	agents	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	simultaneous	_	ADJ	_	Degree=Pos	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	PKC	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	elevation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
14	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	T-leukemia	_	PROPN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	line	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
30	that	_	SCONJ	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	previously	_	ADV	_	_	_	_	_	_
33	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	interaction	_	NOUN	_	Number=Sing	_	_	_	_
35	between	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	parallel	_	ADJ	_	Degree=Pos	_	_	_	_
38	signal	_	NOUN	_	Number=Sing	_	_	_	_
39	transduction	_	NOUN	_	Number=Sing	_	_	_	_
40	pathways	_	NOUN	_	Number=Plur	_	_	_	_
41	may	_	AUX	_	VerbForm=Fin	_	_	_	_
42	have	_	VERB	_	VerbForm=Inf	_	_	_	_
43	functional	_	ADJ	_	Degree=Pos	_	_	_	_
44	consequences	_	NOUN	_	Number=Plur	_	_	_	_
45	at	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	level	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	gene	_	NOUN	_	Number=Sing	_	_	_	_
50	transcription	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002498	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	c	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Myb	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Ets	_	NOUN	_	Number=Sing	_	_	_	_
6	proteins	_	NOUN	_	Number=Plur	_	_	_	_
7	synergize	_	VERB	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	overcome	_	VERB	_	VerbForm=Inf	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	repression	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	ZEB	_	PROPN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Zfh	_	PROPN	_	Number=Sing	_	_	_	_
3	family	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	zinc	_	NOUN	_	Number=Sing	_	_	_	_
6	finger	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	homeodomain	_	NOUN	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	first	_	ADV	_	_	_	_	_	_
12	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	Drosophila	_	PROPN	_	Number=Sing	_	_	_	_
15	where	_	ADV	_	PronType=Rel	_	_	_	_
16	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	tissues	_	NOUN	_	Number=Plur	_	_	_	_
23	such	_	ADJ	_	Degree=Pos	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	central	_	ADJ	_	Degree=Pos	_	_	_	_
27	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
28	system	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	muscle	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	ZEB	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	vertebrate	_	ADJ	_	Degree=Pos	_	_	_	_
5	homolog	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Zfh	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	subset	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	E	_	NOUN	_	Number=Sing	_	_	_	_
16	boxes	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	blocks	_	NOUN	_	Number=Plur	_	_	_	_
19	myogenesis	_	NOUN	_	Number=Sing	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	repression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	muscle	_	NOUN	_	Number=Sing	_	_	_	_
25	genes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	present	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	evidence	_	NOUN	_	Number=Sing	_	_	_	_
4	here	_	ADV	_	PronType=Dem	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	ZEB	_	PROPN	_	Number=Sing	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	SCONJ	_	_	_	_	_	_
13	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
14	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	families	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	normal	_	ADJ	_	Degree=Pos	_	_	_	_
11	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	c	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	Myb	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	Ets	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	act	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	synergistically	_	ADV	_	_	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	synergy	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	at	_	ADV	_	_	_	_	_	_
18	least	_	ADV	_	Degree=Sup	_	_	_	_
19	several	_	ADJ	_	Degree=Pos	_	_	_	_
20	important	_	ADJ	_	Degree=Pos	_	_	_	_
21	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	ZEB	_	PROPN	_	Number=Sing	_	_	_	_
2	blocks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	c	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	Myb	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	Ets	_	NOUN	_	Number=Sing	_	_	_	_
11	individually	_	ADV	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	together	_	ADV	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	synergize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	resist	_	VERB	_	VerbForm=Inf	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	repression	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Such	_	ADJ	_	Degree=Pos	_	_	_	_
2	repression	_	NOUN	_	Number=Sing	_	_	_	_
3	imposes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	requirement	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	both	_	CCONJ	_	_	_	_	_	_
8	c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	Myb	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Ets	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	providing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	one	_	NUM	_	NumType=Card	_	_	_	_
19	explanation	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	why	_	ADV	_	PronType=Int	_	_	_	_
22	synergy	_	NOUN	_	Number=Sing	_	_	_	_
23	between	_	ADP	_	_	_	_	_	_
24	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
25	factors	_	NOUN	_	Number=Plur	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	important	_	ADJ	_	Degree=Pos	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	balance	_	NOUN	_	Number=Sing	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	repression	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	ZEB	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	c-Myb	_	PROPN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	Ets	_	NOUN	_	Number=Sing	_	_	_	_
14	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	flexible	_	ADJ	_	Degree=Pos	_	_	_	_
17	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	SCONJ	_	_	_	_	_	_
20	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	one	_	NUM	_	NumType=Card	_	_	_	_
5	target	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	positive	_	ADJ	_	Degree=Pos	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	negative	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vivo	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	alpha4	_	NOUN	_	Number=Sing	_	_	_	_
17	integrin	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	key	_	ADJ	_	Degree=Pos	_	_	_	_
23	role	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	normal	_	ADJ	_	Degree=Pos	_	_	_	_
26	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	function	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	mature	_	ADJ	_	Degree=Pos	_	_	_	_
31	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002502	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	tumor	_	NOUN	_	Number=Sing	_	_	_	_
7	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	signalsome	_	ADJ	_	Degree=Pos	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IkappaB	_	ADJ	_	Number=Sing	_	_	_	_
17	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	mediators	_	NOUN	_	Number=Plur	_	_	_	_
4	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	LPS	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	TNF	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	potent	_	ADJ	_	Degree=Pos	_	_	_	_
17	activators	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
11	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	IKK	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	signalsome	_	ADJ	_	Degree=Pos	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	IkappaB	_	ADJ	_	Degree=Pos	_	_	_	_
20	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	role	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	signalsome	_	ADJ	_	Number=Sing	_	_	_	_
34	proteins	_	NOUN	_	Number=Plur	_	_	_	_
35	IKK	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	alpha	_	PROPN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	IKK	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	beta	_	PROPN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	NF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
48	kinase	_	NOUN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	NIK	_	PROPN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	IKK	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	gamma	_	PROPN	_	Number=Sing	_	_	_	_
56	(	_	PUNCT	_	_	_	_	_	_
57	NF	_	PROPN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
60	essential	_	ADJ	_	Degree=Pos	_	_	_	_
61	modulator	_	NOUN	_	Number=Sing	_	_	_	_
62	)	_	PUNCT	_	_	_	_	_	_
63	,	_	PUNCT	_	_	_	_	_	_
64	and	_	CCONJ	_	_	_	_	_	_
65	IKK	_	PROPN	_	Number=Sing	_	_	_	_
66	complex	_	NOUN	_	Number=Sing	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
69	protein	_	NOUN	_	Number=Sing	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	Kinase	_	PROPN	_	Number=Sing	_	_	_	_
2	assays	_	NOUN	_	Number=Plur	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TNF	_	PROPN	_	Number=Sing	_	_	_	_
6	elicited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	short	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	lived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IKK	_	PROPN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	fold	_	VERB	_	Number=Sing	_	_	_	_
22	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
23	effect	_	NOUN	_	Number=Sing	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	IKK	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	alpha	_	PROPN	_	Number=Sing	_	_	_	_
28	than	_	ADP	_	_	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	IKK	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	beta	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	peaking	_	VERB	_	Number=Sing	_	_	_	_
35	at	_	ADP	_	_	_	_	_	_
36	5	_	NUM	_	NumType=Card	_	_	_	_
37	min	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	LPS	_	PROPN	_	Number=Sing	_	_	_	_
5	predominantly	_	ADV	_	_	_	_	_	_
6	stimulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	IKK	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	beta	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	slowly	_	ADV	_	_	_	_	_	_
14	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	peaking	_	VERB	_	VerbForm=Ger	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	30	_	NUM	_	NumType=Card	_	_	_	_
19	min	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	peak	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	later	_	ADJ	_	Degree=Cmp	_	_	_	_
9	time	_	NOUN	_	Number=Sing	_	_	_	_
10	point	_	NOUN	_	Number=Sing	_	_	_	_
11	following	_	VERB	_	VerbForm=Ger	_	_	_	_
12	LPS	_	PROPN	_	Number=Sing	_	_	_	_
13	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	consisted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	IKK	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	beta	_	NOUN	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	signalsome	_	NOUN	_	Number=Sing	_	_	_	_
7	components	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	unaffected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	association	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	IKK	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	NIK	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Exposure	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	LPS	_	NOUN	_	Number=Sing	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	TNF	_	PROPN	_	Number=Sing	_	_	_	_
6	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	differential	_	ADJ	_	Degree=Pos	_	_	_	_
9	patterns	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
18	disappearance	_	NOUN	_	Number=Sing	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	reassembly	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	signalsome	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	whereas	_	SCONJ	_	_	_	_	_	_
27	IKK	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	alpha	_	PROPN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	IKK	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	beta	_	PROPN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	NIK	_	PROPN	_	Number=Sing	_	_	_	_
37	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	complex	_	ADJ	_	Degree=Pos	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	NIK	_	PROPN	_	Number=Sing	_	_	_	_
2	can	_	AUX	_	VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	phosphorylate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	directly	_	ADV	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
12	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	functionally	_	ADV	_	_	_	_	_	_
17	important	_	ADJ	_	Degree=Pos	_	_	_	_
18	subunit	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	because	_	SCONJ	_	_	_	_	_	_
21	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	NIK	_	PROPN	_	Number=Sing	_	_	_	_
23	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	stimulus	_	ADJ	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	more	_	ADV	_	_	_	_	_	_
32	effectively	_	ADV	_	_	_	_	_	_
33	than	_	ADP	_	_	_	_	_	_
34	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	IKK	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	beta	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IKK	_	PROPN	_	Number=Sing	_	_	_	_
4	complex	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	stimulus	_	ADJ	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	whereas	_	SCONJ	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	essential	_	ADJ	_	Degree=Pos	_	_	_	_
19	modulator	_	NOUN	_	Number=Sing	_	_	_	_
20	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	understanding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	LPS	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	signaling	_	NOUN	_	Number=Sing	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	allow	_	VERB	_	VerbForm=Inf	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	development	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	strategies	_	NOUN	_	Number=Plur	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	treat	_	VERB	_	VerbForm=Inf	_	_	_	_
20	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	disease	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002513	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Extinction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	B	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	upon	_	ADP	_	_	_	_	_	_
10	fusion	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	preceded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	depletion	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	essential	_	ADJ	_	Degree=Pos	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	widespread	_	ADJ	_	Degree=Pos	_	_	_	_
29	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	genes	_	NOUN	_	Number=Plur	_	_	_	_
32	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	B	_	NUM	_	Degree=Pos	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	specific	_	ADJ	_	Degree=Pos	_	_	_	_
39	manner	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	Ig	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	fused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	non-B	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_

1	Ig	_	PROPN	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	rapidly	_	ADV	_	_	_	_	_	_
5	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	level	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
14	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	extinction	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
5	fusion	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	either	_	CCONJ	_	_	_	_	_	_
11	diploid	_	NOUN	_	Degree=Pos	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	tetraploid	_	VERB	_	Degree=Pos	_	_	_	_
14	B	_	ADJ	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	Daudi	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	results	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	widespread	_	ADJ	_	Degree=Pos	_	_	_	_
22	extinction	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	several	_	ADJ	_	Degree=Pos	_	_	_	_
25	other	_	ADJ	_	Degree=Pos	_	_	_	_
26	B	_	ADJ	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	that	_	PRON	_	PronType=Rel	_	_	_	_
32	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	B	_	ADJ	_	Degree=Pos	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	specific	_	ADJ	_	Degree=Pos	_	_	_	_
40	manner	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	B	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	controls	_	NOUN	_	Number=Plur	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	s	_	X	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	underlying	_	ADJ	_	Degree=Pos	_	_	_	_
11	Ig	_	NOUN	_	Degree=Pos	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	extinction	_	NOUN	_	Number=Sing	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	explained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	at	_	ADV	_	_	_	_	_	_
19	least	_	ADV	_	Degree=Sup	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	part	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	lack	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	essential	_	ADJ	_	Degree=Pos	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	Ig	_	NOUN	_	Degree=Pos	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	either	_	CCONJ	_	_	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	due	_	ADP	_	_	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	block	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	respective	_	ADJ	_	Degree=Pos	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	Oct	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	OBF	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	rendered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
33	posttranslationally	_	ADV	_	_	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	PROPN	_	Number=Sing	_	_	_	_
38	B	_	PROPN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	E47	_	PROPN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	isolating	_	VERB	_	VerbForm=Ger	_	_	_	_
3	Daudi	_	PROPN	_	Number=Sing	_	_	_	_
4	x	_	PROPN	_	_	_	_	_	_
5	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
6	heterokaryons	_	NOUN	_	Number=Plur	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	few	_	ADJ	_	Degree=Pos	_	_	_	_
9	hours	_	NOUN	_	Number=Plur	_	_	_	_
10	after	_	ADP	_	_	_	_	_	_
11	fusion	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	initial	_	ADJ	_	Degree=Pos	_	_	_	_
18	fate	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	two	_	NUM	_	NumType=Card	_	_	_	_
21	B	_	NOUN	_	NumType=Card	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	factors	_	NOUN	_	Number=Plur	_	_	_	_
27	involved	_	ADJ	_	Degree=Pos	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	Ig	_	PROPN	_	Number=Sing	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	Oct	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kappa	_	PROPN	_	Number=Sing	_	_	_	_
40	B	_	PROPN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	report	_	NOUN	_	Number=Sing	_	_	_	_
3	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	demonstration	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	_	_	_	_	_
8	upon	_	ADP	_	_	_	_	_	_
9	fusion	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	contents	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	B	_	ADJ	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	depleted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	within	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	few	_	ADJ	_	Degree=Pos	_	_	_	_
29	hours	_	NOUN	_	Number=Plur	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
32	that	_	PRON	_	PronType=Rel	_	_	_	_
33	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	as	_	ADV	_	_	_	_	_	_
35	fast	_	ADJ	_	Degree=Pos	_	_	_	_
36	or	_	CCONJ	_	_	_	_	_	_
37	faster	_	ADJ	_	Degree=Cmp	_	_	_	_
38	than	_	ADP	_	_	_	_	_	_
39	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	Ig	_	NOUN	_	Degree=Pos	_	_	_	_
42	gene	_	NOUN	_	Number=Sing	_	_	_	_
43	extinction	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	extinguishing	_	NOUN	_	Number=Sing	_	_	_	_
5	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	effective	_	ADJ	_	Degree=Pos	_	_	_	_
8	very	_	ADV	_	_	_	_	_	_
9	early	_	ADV	_	Degree=Pos	_	_	_	_
10	after	_	ADP	_	_	_	_	_	_
11	fusion	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
4	extinction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Ig	_	NOUN	_	Degree=Pos	_	_	_	_
7	genes	_	NOUN	_	Number=Plur	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	part	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	global	_	ADJ	_	Degree=Pos	_	_	_	_
13	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	program	_	NOUN	_	Number=Sing	_	_	_	_
19	foreign	_	NOUN	_	Degree=Pos	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
23	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002514	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Sequential	_	ADJ	_	Degree=Pos	_	_	_	_
2	development	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	structural	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	functional	_	ADJ	_	Degree=Pos	_	_	_	_
7	alterations	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	tumor	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	mice	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	TCR	_	NOUN	_	Number=Sing	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	beta	_	NOUN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	gamma	_	PROPN	_	Number=Sing	_	_	_	_
8	delta	_	NOUN	_	Number=Sing	_	_	_	_
9	chains	_	NOUN	_	Number=Plur	_	_	_	_
10	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	peptide	_	NOUN	_	Number=Sing	_	_	_	_
13	ligand	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	whereas	_	SCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	CD3	_	PROPN	_	Number=Sing	_	_	_	_
19	deltaepsilongamma	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	TCR	_	NOUN	_	Number=Sing	_	_	_	_
22	zeta	_	NOUN	_	Number=Sing	_	_	_	_
23	subunits	_	NOUN	_	Number=Plur	_	_	_	_
24	couple	_	NOUN	_	Number=Sing	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	TCR	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
29	signal	_	NOUN	_	Number=Sing	_	_	_	_
30	transduction	_	NOUN	_	Number=Sing	_	_	_	_
31	components	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	several	_	ADJ	_	Degree=Pos	_	_	_	_
4	groups	_	NOUN	_	Number=Plur	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	alterations	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	signal	_	ADJ	_	Number=Sing	_	_	_	_
11	transduction	_	NOUN	_	Number=Sing	_	_	_	_
12	elements	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	cancer	_	NOUN	_	Number=Sing	_	_	_	_
18	patients	_	NOUN	_	Number=Plur	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	mice	_	NOUN	_	Number=Plur	_	_	_	_
22	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	tumor	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	few	_	ADJ	_	Degree=Pos	_	_	_	_
27	weeks	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	>	_	SYM	_	_	_	_	_	_
30	26	_	NUM	_	NumType=Card	_	_	_	_
31	days	_	NOUN	_	Number=Plur	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	alterations	_	NOUN	_	Number=Plur	_	_	_	_
7	develop	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	aim	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	explore	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	development	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	alterations	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	signal	_	NOUN	_	Number=Sing	_	_	_	_
18	transduction	_	NOUN	_	Number=Sing	_	_	_	_
19	molecules	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	TCR	_	PROPN	_	Number=Sing	_	_	_	_
22	zeta	_	NOUN	_	Number=Sing	_	_	_	_
23	chain	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	family	_	NOUN	_	Number=Sing	_	_	_	_
28	proteins	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
32	kinase	_	NOUN	_	Number=Sing	_	_	_	_
33	p56	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	lck	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	mice	_	NOUN	_	Number=Plur	_	_	_	_
40	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
41	MC38	_	PROPN	_	Number=Sing	_	_	_	_
42	colon	_	NOUN	_	Number=Sing	_	_	_	_
43	adenocarcinoma	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	alterations	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
9	family	_	NOUN	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	specifically	_	ADV	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	failure	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	p65	_	NOUN	_	Number=Sing	_	_	_	_
17	translocation	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
23	earlier	_	ADV	_	Degree=Cmp	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	more	_	ADV	_	_	_	_	_	_
26	frequently	_	ADV	_	_	_	_	_	_
27	than	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	decrease	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	zeta-chain	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	defects	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	paralleled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
8	ability	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
11	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	IFN	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	gamma	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	initial	_	ADJ	_	Degree=Pos	_	_	_	_
3	changes	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	followed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	eventual	_	ADJ	_	Degree=Pos	_	_	_	_
9	loss	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	TCR	_	PROPN	_	Number=Sing	_	_	_	_
12	zeta	_	NOUN	_	Number=Sing	_	_	_	_
13	chain	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	p56	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	lck	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	decrease	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
25	function	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	rate	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	lysosomal	_	ADJ	_	Degree=Pos	_	_	_	_
6	degradation	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	one	_	NUM	_	NumType=Card	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
12	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	loss	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	zeta-chain	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002520	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Thymocytes	_	PROPN	_	Number=Plur	_	_	_	_
2	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CD4	_	PROPN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	differently	_	ADV	_	_	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	mature	_	ADJ	_	Degree=Pos	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	silencer	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	CD4	_	PROPN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	during	_	ADP	_	_	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	development	_	NOUN	_	Number=Sing	_	_	_	_
23	using	_	VERB	_	VerbForm=Ger	_	_	_	_
24	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
25	mice	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
5	populations	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	mice	_	NOUN	_	Number=Plur	_	_	_	_
8	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
9	transgenes	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	various	_	ADJ	_	Degree=Pos	_	_	_	_
12	combinations	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	elements	_	NOUN	_	Number=Plur	_	_	_	_
18	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	CD4	_	PROPN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	different	_	ADJ	_	Degree=Pos	_	_	_	_
28	manner	_	NOUN	_	Number=Sing	_	_	_	_
29	than	_	ADP	_	_	_	_	_	_
30	mature	_	ADJ	_	Degree=Pos	_	_	_	_
31	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	5	_	NUM	_	NumType=Card	_	_	_	_
3	'-	_	PUNCT	_	_	_	_	_	_
4	positive	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	unit	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	consisting	_	VERB	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	5	_	NUM	_	NumType=Card	_	_	_	_
15	'	_	PUNCT	_	_	_	_	_	_
16	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	already	_	ADV	_	_	_	_	_	_
20	active	_	ADJ	_	Degree=Pos	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	CD4-CD8	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	double-negative	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	DN	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	stage	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	development	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	becomes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	double	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	positive	_	ADJ	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	fraction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	CD4	_	NOUN	_	Number=Sing	_	_	_	_
18	+	_	SYM	_	_	_	_	_	_

1	CD8int	_	NOUN	_	Number=Sing	_	_	_	_
2	/-	_	PUNCT	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	population	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	additional	_	ADJ	_	Degree=Pos	_	_	_	_
10	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	either	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	third	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
20	intron	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	CD4	_	PROPN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	CD4	_	PROPN	_	Number=Sing	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
34	population	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	element	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
9	CD4	_	NOUN	_	Number=Sing	_	_	_	_
10	silencer	_	NOUN	_	Number=Sing	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	CD4	_	PROPN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
18	CD8	_	NOUN	_	Number=Sing	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	silencer	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	most	_	ADV	_	_	_	_	_	_
8	immature	_	ADJ	_	Degree=Pos	_	_	_	_
9	DN	_	NOUN	_	Number=Sing	_	_	_	_
10	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	probably	_	ADV	_	_	_	_	_	_
14	use	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
17	silencer	_	NOUN	_	Number=Sing	_	_	_	_
18	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	down	_	ADV	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	regulate	_	VERB	_	Degree=Pos	_	_	_	_
23	CD4	_	PROPN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Unexpectedly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CD4	_	PROPN	_	Number=Sing	_	_	_	_
5	silencer	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	active	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	CD4	_	PROPN	_	Number=Sing	_	_	_	_
11	+	_	SYM	_	_	_	_	_	_

1	CD8int	_	NOUN	_	Number=Sing	_	_	_	_
2	/-	_	PUNCT	_	_	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	thymus	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	implying	_	VERB	_	VerbForm=Ger	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	anti-silencer	_	NOUN	_	Number=Sing	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	resume	_	VERB	_	VerbForm=Inf	_	_	_	_
17	CD4	_	PROPN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	population	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Altogether	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CD4	_	PROPN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	several	_	ADJ	_	Degree=Pos	_	_	_	_
10	positive	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	negative	_	ADJ	_	Degree=Pos	_	_	_	_
13	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	come	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	into	_	ADP	_	_	_	_	_	_
18	play	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	developmentally	_	ADV	_	_	_	_	_	_
22	coordinated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	manner	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002530	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Globin	_	PROPN	_	Degree=Pos	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	switching	_	VERB	_	Number=Sing	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	interactions	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	beta-globin	_	NOUN	_	Number=Sing	_	_	_	_
11	locus	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	fetal	_	NOUN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	adult	_	NOUN	_	Number=Sing	_	_	_	_
21	globin	_	NOUN	_	Degree=Pos	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	program	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	DNA	_	NOUN	_	Number=Sing	_	_	_	_
7	interactions	_	NOUN	_	Number=Plur	_	_	_	_
8	important	_	ADJ	_	Degree=Pos	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
12	control	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	beta-globin	_	NOUN	_	Number=Sing	_	_	_	_
17	locus	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	vivo	_	NOUN	_	Number=Sing	_	_	_	_
24	dimethyl	_	NOUN	_	Degree=Pos	_	_	_	_
25	sulfate	_	NOUN	_	Number=Sing	_	_	_	_
26	footprinting	_	VERB	_	VerbForm=Ger	_	_	_	_
27	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
30	either	_	CCONJ	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	fetal	_	NOUN	_	Number=Sing	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	adult	_	NOUN	_	Number=Sing	_	_	_	_
36	globin	_	NOUN	_	Number=Sing	_	_	_	_
37	developmental	_	NOUN	_	Degree=Pos	_	_	_	_
38	program	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	locus	_	NOUN	_	Number=Sing	_	_	_	_
4	control	_	NOUN	_	Number=Sing	_	_	_	_
5	region	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	LCR	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	globin	_	NOUN	_	Number=Sing	_	_	_	_
14	locus	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	vivo	_	NOUN	_	Number=Sing	_	_	_	_
18	footprints	_	NOUN	_	Number=Plur	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	E2	_	PROPN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	AP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	GATA	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	motifs	_	NOUN	_	Number=Plur	_	_	_	_
34	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	same	_	ADJ	_	Degree=Pos	_	_	_	_
37	regardless	_	ADV	_	_	_	_	_	_
38	of	_	SCONJ	_	_	_	_	_	_
39	whether	_	SCONJ	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	fetal	_	NOUN	_	Number=Sing	_	_	_	_
42	or	_	CCONJ	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	adult	_	NOUN	_	Number=Sing	_	_	_	_
45	globin	_	NOUN	_	Degree=Pos	_	_	_	_
46	genes	_	NOUN	_	Number=Plur	_	_	_	_
47	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
48	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	vivo	_	NOUN	_	Number=Sing	_	_	_	_
6	footprints	_	NOUN	_	Number=Plur	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	GT	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	CACCC	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	motifs	_	NOUN	_	Number=Plur	_	_	_	_
13	differed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	between	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	fetal	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	adult	_	NOUN	_	Number=Sing	_	_	_	_
23	globin	_	NOUN	_	Number=Sing	_	_	_	_
24	program	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	promoter	_	NOUN	_	Number=Sing	_	_	_	_
3	regions	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	actively	_	ADV	_	_	_	_	_	_
7	transcribed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	extensive	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
13	footprints	_	NOUN	_	Number=Plur	_	_	_	_
14	over	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	canonical	_	ADJ	_	Degree=Pos	_	_	_	_
17	elements	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	such	_	ADJ	_	Degree=Pos	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	CACCC	_	PROPN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	CCAAT	_	ADJ	_	Number=Sing	_	_	_	_
24	motifs	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	adult	_	NOUN	_	Number=Sing	_	_	_	_
3	globin	_	NOUN	_	Number=Sing	_	_	_	_
4	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	displayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	more	_	ADV	_	_	_	_	_	_
8	extensive	_	ADJ	_	Degree=Pos	_	_	_	_
9	footprints	_	NOUN	_	Number=Plur	_	_	_	_
10	than	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	fetal	_	ADJ	_	Number=Sing	_	_	_	_
13	globin	_	NOUN	_	Number=Sing	_	_	_	_
14	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	3	_	NUM	_	NumType=Card	_	_	_	_
19	'	_	PUNCT	_	_	_	_	_	_
20	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	sequences	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	both	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	Agamma	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	beta	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	globin	_	ADJ	_	Degree=Pos	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	role	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
39	3	_	NUM	_	NumType=Card	_	_	_	_
40	'	_	PUNCT	_	_	_	_	_	_
41	elements	_	NOUN	_	Number=Plur	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	beta	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	globin	_	ADJ	_	Degree=Pos	_	_	_	_
46	gene	_	NOUN	_	Number=Sing	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	bulk	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	DNA	_	PROPN	_	Number=Sing	_	_	_	_
11	interactions	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	underlies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
16	control	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	globin	_	ADJ	_	Degree=Pos	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	takes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	place	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	gamma	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	beta-globin	_	ADJ	_	Degree=Pos	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	promoters	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	that	_	SCONJ	_	_	_	_	_	_
33	GT	_	NOUN	_	Number=Sing	_	_	_	_
34	motifs	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	beta	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	globin	_	NOUN	_	Degree=Pos	_	_	_	_
40	locus	_	NOUN	_	Number=Sing	_	_	_	_
41	LCR	_	PROPN	_	Number=Sing	_	_	_	_
42	may	_	AUX	_	VerbForm=Fin	_	_	_	_
43	play	_	VERB	_	VerbForm=Inf	_	_	_	_
44	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
45	role	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
49	regulation	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	human	_	ADJ	_	Degree=Pos	_	_	_	_
52	beta-globin	_	NOUN	_	Degree=Pos	_	_	_	_
53	gene	_	NOUN	_	Number=Sing	_	_	_	_
54	expression	_	NOUN	_	Number=Sing	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	perhaps	_	ADV	_	_	_	_	_	_
57	by	_	SCONJ	_	_	_	_	_	_
58	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
59	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
60	probability	_	NOUN	_	Number=Sing	_	_	_	_
61	of	_	ADP	_	_	_	_	_	_
62	interaction	_	NOUN	_	Number=Sing	_	_	_	_
63	of	_	ADP	_	_	_	_	_	_
64	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
65	LCR	_	NOUN	_	Number=Sing	_	_	_	_
66	holocomplex	_	NOUN	_	Number=Sing	_	_	_	_
67	with	_	ADP	_	_	_	_	_	_
68	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
69	fetal	_	NOUN	_	Number=Sing	_	_	_	_
70	or	_	CCONJ	_	_	_	_	_	_
71	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
72	adult	_	NOUN	_	Number=Sing	_	_	_	_
73	globin	_	NOUN	_	Degree=Pos	_	_	_	_
74	gene	_	NOUN	_	Number=Sing	_	_	_	_
75	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002536	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	4E-BP1	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	4E	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	BP2	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	repressors	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	translation	_	NOUN	_	Number=Sing	_	_	_	_
14	initiation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	during	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
3	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	decrease	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	translation	_	NOUN	_	Number=Sing	_	_	_	_
4	rate	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	important	_	ADJ	_	Degree=Pos	_	_	_	_
8	determinant	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	translation	_	NOUN	_	Number=Sing	_	_	_	_
17	initiation	_	NOUN	_	Number=Sing	_	_	_	_
18	during	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	using	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	HL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	60	_	NUM	_	NumType=Card	_	_	_	_
28	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
29	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	line	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	U	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	937	_	NUM	_	NumType=Card	_	_	_	_
37	monoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	line	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	decrease	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	translation	_	NOUN	_	Number=Sing	_	_	_	_
6	rate	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	when	_	ADV	_	PronType=Int	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	along	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
21	pathway	_	NOUN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	along	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
26	pathway	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
6	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	regulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	two	_	NUM	_	NumType=Card	_	_	_	_
12	repressors	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	translation	_	NOUN	_	Number=Sing	_	_	_	_
15	initiation	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	4E	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	BP1	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	4E	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	BP2	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	60	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	U-937	_	NUM	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
10	into	_	ADP	_	_	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	IFN	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	gamma	_	NOUN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	PMA	_	NOUN	_	Number=Sing	_	_	_	_
20	results	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	consequent	_	ADJ	_	Degree=Pos	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	4E-BP1	_	NOUN	_	NumType=Card	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	4E-BP1	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	when	_	ADV	_	PronType=Int	_	_	_	_
8	U	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	937	_	NUM	_	NumType=Card	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	into	_	ADP	_	_	_	_	_	_
17	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
20	following	_	VERB	_	VerbForm=Ger	_	_	_	_
21	treatment	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
24	acid	_	NOUN	_	Number=Sing	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	DMSO	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	HL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	60	_	NUM	_	NumType=Card	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
12	acid	_	NOUN	_	Number=Sing	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	DMSO	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	results	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	decreases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	4E	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	BP1	_	NOUN	_	Number=Sing	_	_	_	_
30	amount	_	NOUN	_	Number=Sing	_	_	_	_
31	without	_	SCONJ	_	_	_	_	_	_
32	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
33	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	strongly	_	ADV	_	_	_	_	_	_
37	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	4E	_	NUM	_	NumType=Card	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	BP2	_	NOUN	_	Number=Sing	_	_	_	_
41	amount	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	evidence	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	differential	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	translational	_	ADJ	_	Degree=Pos	_	_	_	_
14	machinery	_	NOUN	_	Number=Sing	_	_	_	_
15	during	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
26	pathway	_	NOUN	_	Number=Sing	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
31	pathway	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002537	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	11	_	NUM	_	NumType=Card	_	_	_	_
7	during	_	ADP	_	_	_	_	_	_
8	acute	_	ADJ	_	Degree=Pos	_	_	_	_
9	lung	_	NOUN	_	Number=Sing	_	_	_	_
10	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	injury	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	11	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	11	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	IgG	_	PROPN	_	Number=Sing	_	_	_	_
17	immune	_	ADJ	_	Number=Sing	_	_	_	_
18	complex	_	ADJ	_	Number=Sing	_	_	_	_
19	model	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	acute	_	ADJ	_	Degree=Pos	_	_	_	_
22	lung	_	NOUN	_	Number=Sing	_	_	_	_
23	injury	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	rats	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	11	_	NUM	_	NumType=Card	_	_	_	_
4	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	both	_	ADV	_	_	_	_	_	_
9	up	_	ADJ	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	regulated	_	ADJ	_	Degree=Pos	_	_	_	_
12	during	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	course	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Exogenously	_	ADV	_	_	_	_	_	_
2	administered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	11	_	NUM	_	NumType=Card	_	_	_	_
6	substantially	_	ADV	_	_	_	_	_	_
7	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	dose	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	manner	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	intrapulmonary	_	ADJ	_	Degree=Pos	_	_	_	_
18	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	lung	_	ADJ	_	Number=Sing	_	_	_	_
24	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
25	leak	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	albumin	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	vivo	_	ADJ	_	Degree=Pos	_	_	_	_
4	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	11	_	NUM	_	NumType=Card	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	lung	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	levels	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	tumor	_	NOUN	_	Number=Sing	_	_	_	_
25	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	TNF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	bronchoalveolar	_	NOUN	_	Number=Sing	_	_	_	_
35	lavage	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	BAL	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	fluids	_	NOUN	_	Number=Plur	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	diminished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	up	_	ADP	_	_	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	regulation	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	lung	_	NOUN	_	Number=Sing	_	_	_	_
48	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
49	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	1	_	NUM	_	NumType=Card	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	interesting	_	ADJ	_	Degree=Pos	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	11	_	NUM	_	NumType=Card	_	_	_	_
8	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
11	BAL	_	ADJ	_	Number=Sing	_	_	_	_
12	fluid	_	NOUN	_	Number=Sing	_	_	_	_
13	content	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	CXC	_	NOUN	_	Number=Sing	_	_	_	_
17	chemokines	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
20	inflammatory	_	NOUN	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	MIP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
33	neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
34	chemoattractant	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	CINC	_	PROPN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	;	_	PUNCT	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	presence	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	11	_	NUM	_	NumType=Card	_	_	_	_
45	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
46	not	_	PART	_	_	_	_	_	_
47	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
48	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
49	chemokines	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	BAL	_	PROPN	_	Number=Sing	_	_	_	_
4	content	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	C5a	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	11	_	NUM	_	NumType=Card	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	11	_	NUM	_	NumType=Card	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	lung	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	like	_	ADP	_	_	_	_	_	_
19	other	_	ADJ	_	Degree=Pos	_	_	_	_
20	members	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
23	family	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	properties	_	NOUN	_	Number=Plur	_	_	_	_
28	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	suppression	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	diminished	_	VERB	_	Degree=Pos	_	_	_	_
42	production	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	TNF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	alpha	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	up	_	ADP	_	_	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	regulation	_	NOUN	_	Number=Sing	_	_	_	_
53	of	_	ADP	_	_	_	_	_	_
54	lung	_	NOUN	_	Number=Sing	_	_	_	_
55	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
56	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	1	_	NUM	_	NumType=Card	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_
60	Document	_	NOUN	_	Number=Sing	_	_	_	_
61	003002544	_	NUM	_	NumType=Card	_	_	_	_
62	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	v-erbA	_	PROPN	_	Degree=Pos	_	_	_	_
2	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	extinguish	_	VERB	_	VerbForm=Inf	_	_	_	_
7	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
8	function	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	erbA	_	PROPN	_	Number=Sing	_	_	_	_
18	target	_	NOUN	_	Number=Sing	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	CAII	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	v-erbA	_	NOUN	_	Number=Sing	_	_	_	_
3	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
4	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	retrovirus	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	oncogenic	_	ADJ	_	Degree=Pos	_	_	_	_
10	version	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
14	hormone	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	T3	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	T4	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	type	_	NOUN	_	Number=Sing	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	erythroleukemia	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	SCONJ	_	_	_	_	_	_
9	efficiently	_	ADV	_	_	_	_	_	_
10	arresting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	red	_	ADJ	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	by	_	SCONJ	_	_	_	_	_	_
18	suppressing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	erythrocyte	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	v-erbA	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
9	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	directly	_	ADV	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	sequences	_	NOUN	_	Number=Plur	_	_	_	_
13	within	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	erythrocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	carbonic	_	ADJ	_	Number=Sing	_	_	_	_
22	anhydrase	_	NOUN	_	Number=Sing	_	_	_	_
23	II	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	CAII	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	efficiently	_	ADV	_	_	_	_	_	_
34	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	v-erbA	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	erbA	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
8	hormone	_	NOUN	_	Number=Sing	_	_	_	_
9	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	transient	_	ADJ	_	Degree=Pos	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	experiments	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	target	_	NOUN	_	Number=Sing	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
24	down	_	ADP	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	regulation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	CAII	_	NOUN	_	Number=Sing	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	v-erbA	_	NOUN	_	Number=Sing	_	_	_	_
33	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	stably	_	ADV	_	_	_	_	_	_
3	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
5	coexpressing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	v-erbA	_	NOUN	_	Number=Sing	_	_	_	_
8	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	T3	_	NOUN	_	Number=Sing	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	approximately	_	ADV	_	_	_	_	_	_
18	equimolar	_	ADJ	_	Degree=Pos	_	_	_	_
19	ratio	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	c	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	erbA	_	PROPN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
27	over	_	ADP	_	_	_	_	_	_
28	v-erbA	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	T3	_	PROPN	_	_	_	_	_	_
2	efficiently	_	ADV	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	thus	_	ADV	_	_	_	_	_	_
11	overcoming	_	VERB	_	VerbForm=Ger	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	v-erbA	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	arrest	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Likewise	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	T3	_	PROPN	_	Number=Sing	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	CAII	_	PROPN	_	Number=Sing	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	as	_	ADV	_	_	_	_	_	_
8	well	_	ADV	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	transient	_	ADJ	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	T3	_	NUM	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
17	reporter	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	CAII	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	erbA	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	site	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	CAII	_	PROPN	_	Number=Sing	_	_	_	_
9	reporter	_	NOUN	_	Number=Sing	_	_	_	_
10	construct	_	NOUN	_	Number=Sing	_	_	_	_
11	could	_	AUX	_	VerbForm=Fin	_	_	_	_
12	only	_	ADV	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	very	_	ADV	_	_	_	_	_	_
17	high	_	ADJ	_	Degree=Pos	_	_	_	_
18	amounts	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	v-erbA	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	v-erbA	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	function	_	NOUN	_	Number=Sing	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002548	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	AT	_	ADP	_	_	_	_	_	_
8	complex	_	NOUN	_	Number=Sing	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	restimulation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
16	anergy	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	CD4	_	NOUN	_	Number=Sing	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_

1	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
2	clones	_	NOUN	_	Number=Plur	_	_	_	_
3	through	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	TcR	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	high	_	ADJ	_	Degree=Pos	_	_	_	_
12	doses	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	peptide	_	NOUN	_	Number=Sing	_	_	_	_
16	results	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	long	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	lived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	state	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	nonresponsiveness	_	NOUN	_	Number=Sing	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
31	called	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	anergy	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	During	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	anergy	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	phenotypically	_	ADV	_	_	_	_	_	_
11	similar	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	responding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	immunogenic	_	ADJ	_	Degree=Pos	_	_	_	_
18	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	amount	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TcR	_	NOUN	_	Number=Sing	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	surface	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	downmodulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	whereas	_	SCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	CD2	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	CD25	_	NOUN	_	Number=Sing	_	_	_	_
17	receptors	_	NOUN	_	Number=Plur	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	restimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	however	_	ADV	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	anergic	_	ADJ	_	Degree=Pos	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	fail	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	up	_	ADP	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	regulate	_	VERB	_	Degree=Pos	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	consequence	_	NOUN	_	Number=Sing	_	_	_	_
24	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	ability	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	various	_	ADJ	_	Degree=Pos	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	appropriate	_	ADJ	_	Degree=Pos	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	DNA	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Factors	_	NOUN	_	Number=Plur	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	phase	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	anergy	_	NOUN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	undergoing	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	pattern	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	restimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	pattern	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	previously	_	ADV	_	_	_	_	_	_
18	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
19	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	beta	_	NOUN	_	Number=Sing	_	_	_	_
34	chain	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	TcR	_	NOUN	_	Number=Sing	_	_	_	_
38	genes	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	TCF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	same	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	resting	_	VERB	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	anergized	_	VERB	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	NK	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	PROPN	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	beta	_	PROPN	_	Number=Sing	_	_	_	_
10	E2	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	CD28RC	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	twofold	_	ADJ	_	Number=Sing	_	_	_	_
27	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	anergized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	as	_	SCONJ	_	_	_	_	_	_
31	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	anergic	_	ADJ	_	Degree=Pos	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	approximately	_	ADV	_	_	_	_	_	_
9	eightfold	_	VERB	_	NumType=Card	_	_	_	_
10	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
11	amounts	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	AT	_	ADP	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	member	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	class	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
24	factors	_	NOUN	_	Number=Plur	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	003002549	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	p53	_	NOUN	_	Number=Sing	_	_	_	_
3	paradox	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	tumor	_	NOUN	_	Number=Sing	_	_	_	_
9	progression	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	evidence	_	NOUN	_	Number=Sing	_	_	_	_
3	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	p53	_	NOUN	_	Number=Sing	_	_	_	_
7	molecule	_	NOUN	_	Number=Sing	_	_	_	_
8	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	different	_	ADJ	_	Degree=Pos	_	_	_	_
12	forms	_	NOUN	_	Number=Plur	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	mutant	_	NOUN	_	Number=Sing	_	_	_	_
16	p53	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	tumor	_	NOUN	_	Number=Sing	_	_	_	_
20	progression	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	wild	_	ADJ	_	Degree=Pos	_	_	_	_
24	type	_	NOUN	_	Number=Sing	_	_	_	_
25	p53	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	DET	_	PronType=Rel	_	_	_	_
27	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	tumor	_	NOUN	_	Number=Sing	_	_	_	_
29	progression	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	established	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TNF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	can	_	AUX	_	VerbForm=Fin	_	_	_	_
20	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	wild	_	ADJ	_	Degree=Pos	_	_	_	_
25	type	_	NOUN	_	Number=Sing	_	_	_	_
26	p53	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	concert	_	NOUN	_	Number=Sing	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	PROPN	_	Number=Sing	_	_	_	_
38	B.	_	PROPN	_	Number=Sing	_	_	_	_
39	Both	_	CCONJ	_	_	_	_	_	_
40	TNF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	alpha	_	PROPN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	NF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	kappa	_	PROPN	_	Number=Sing	_	_	_	_
47	B	_	PROPN	_	Number=Sing	_	_	_	_
48	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
49	also	_	ADV	_	_	_	_	_	_
50	involved	_	ADJ	_	Degree=Pos	_	_	_	_
51	in	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	pathway	_	NOUN	_	Number=Sing	_	_	_	_
57	that	_	PRON	_	PronType=Rel	_	_	_	_
58	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
59	to	_	ADP	_	_	_	_	_	_
60	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
61	expression	_	NOUN	_	Number=Sing	_	_	_	_
62	of	_	ADP	_	_	_	_	_	_
63	major	_	ADJ	_	Degree=Pos	_	_	_	_
64	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
65	complex	_	NOUN	_	Number=Sing	_	_	_	_
66	(	_	PUNCT	_	_	_	_	_	_
67	MHC	_	PROPN	_	Number=Sing	_	_	_	_
68	)	_	PUNCT	_	_	_	_	_	_
69	class	_	NOUN	_	Number=Sing	_	_	_	_
70	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
71	molecules	_	VERB	_	Number=Plur	_	_	_	_
72	and	_	CCONJ	_	_	_	_	_	_
73	,	_	PUNCT	_	_	_	_	_	_
74	hence	_	ADV	_	_	_	_	_	_
75	,	_	PUNCT	_	_	_	_	_	_
76	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
77	presentation	_	NOUN	_	Number=Sing	_	_	_	_
78	to	_	ADP	_	_	_	_	_	_
79	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
80	T	_	NOUN	_	Number=Sing	_	_	_	_
81	cells	_	NOUN	_	Number=Plur	_	_	_	_
82	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	paper	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	shall	_	AUX	_	VerbForm=Fin	_	_	_	_
6	advance	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	:	_	PUNCT	_	_	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	i	_	X	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	indirectly	_	ADV	_	_	_	_	_	_
18	controls	_	VERB	_	Number=Plur	_	_	_	_
19	immune	_	ADJ	_	Degree=Pos	_	_	_	_
20	surveillance	_	NOUN	_	Number=Sing	_	_	_	_
21	;	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	ii	_	X	_	_	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	TNF	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	controls	_	VERB	_	Number=Plur	_	_	_	_
30	DNA	_	NOUN	_	Number=Sing	_	_	_	_
31	repair	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	tumor	_	NOUN	_	Number=Sing	_	_	_	_
34	suppression	_	NOUN	_	Number=Sing	_	_	_	_
35	through	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	regulation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	wild	_	NOUN	_	Number=Sing	_	_	_	_
40	type	_	NOUN	_	Number=Sing	_	_	_	_
41	p53	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	hypothesized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	elevated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	primarily	_	ADV	_	_	_	_	_	_
13	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	SCONJ	_	_	_	_	_	_
15	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	tumor	_	NOUN	_	Number=Sing	_	_	_	_
17	progression	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002554	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	lymphotropic	_	ADJ	_	Degree=Pos	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	infection	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	beta	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	galactoside	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	lectin	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	galectin	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	3	_	NUM	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Animal	_	NOUN	_	Number=Sing	_	_	_	_
2	lectins	_	NOUN	_	Number=Plur	_	_	_	_
3	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	important	_	ADJ	_	Degree=Pos	_	_	_	_
5	roles	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	variety	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	biological	_	ADJ	_	Degree=Pos	_	_	_	_
11	processes	_	NOUN	_	Number=Plur	_	_	_	_
12	via	_	ADP	_	_	_	_	_	_
13	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	recognition	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	glycoconjugates	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Galectin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	galactoside	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	lectin	_	NOUN	_	Number=Sing	_	_	_	_
12	previously	_	ADV	_	_	_	_	_	_
13	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
16	BP	_	PROPN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	IgE	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	CBP35	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	Mac	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	L	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	29	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	L	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	34	_	NUM	_	NumType=Card	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
43	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
44	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	with	_	ADP	_	_	_	_	_	_
46	various	_	ADJ	_	Degree=Pos	_	_	_	_
47	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	pathological	_	ADJ	_	Degree=Pos	_	_	_	_
50	processes	_	NOUN	_	Number=Plur	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	including	_	VERB	_	VerbForm=Ger	_	_	_	_
53	cell	_	NOUN	_	Number=Sing	_	_	_	_
54	growth	_	NOUN	_	Number=Sing	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	tumor	_	NOUN	_	Number=Sing	_	_	_	_
57	transformation	_	NOUN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	and	_	CCONJ	_	_	_	_	_	_
60	metastasis	_	NOUN	_	Number=Sing	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	Galectin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	widely	_	ADV	_	_	_	_	_	_
6	distributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	various	_	ADJ	_	Degree=Pos	_	_	_	_
9	tissues	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	types	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	many	_	ADJ	_	Degree=Pos	_	_	_	_
18	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	notable	_	ADJ	_	Degree=Pos	_	_	_	_
23	exception	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	galectin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	3	_	NUM	_	NumType=Card	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	abundantly	_	ADV	_	_	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	number	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	lymphotropic	_	PROPN	_	Degree=Pos	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	lines	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	including	_	VERB	_	VerbForm=Ger	_	_	_	_
32	F6T	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	HUT	_	PROPN	_	Number=Sing	_	_	_	_
35	102	_	NUM	_	NumType=Card	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	K3T	_	PROPN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	MT	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	SLB	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	but	_	CCONJ	_	_	_	_	_	_
49	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
50	not	_	PART	_	_	_	_	_	_
51	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	non-HTLV	_	ADJ	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
58	T	_	NOUN	_	Number=Sing	_	_	_	_
59	cell	_	NOUN	_	Number=Sing	_	_	_	_
60	lines	_	NOUN	_	Number=Plur	_	_	_	_
61	such	_	ADJ	_	Degree=Pos	_	_	_	_
62	as	_	ADP	_	_	_	_	_	_
63	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
64	,	_	PUNCT	_	_	_	_	_	_
65	CEM	_	PROPN	_	Number=Sing	_	_	_	_
66	,	_	PUNCT	_	_	_	_	_	_
67	and	_	CCONJ	_	_	_	_	_	_
68	MOLT	_	NOUN	_	Number=Sing	_	_	_	_
69	-	_	PUNCT	_	_	_	_	_	_
70	4	_	NUM	_	NumType=Card	_	_	_	_
71	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	galectin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	3	_	NUM	_	NumType=Card	_	_	_	_
8	level	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	markedly	_	ADV	_	_	_	_	_	_
11	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	after	_	ADP	_	_	_	_	_	_
16	infection	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	as	_	AUX	_	_	_	_	_	_
22	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	uninfected	_	ADJ	_	Degree=Pos	_	_	_	_
25	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	up	_	ADP	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	galectin	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	correlate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	well	_	ADV	_	Degree=Pos	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	gene	_	VERB	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	as	_	SCONJ	_	_	_	_	_	_
22	undetectable	_	ADJ	_	Degree=Pos	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	very	_	ADV	_	_	_	_	_	_
25	low	_	ADJ	_	Degree=Pos	_	_	_	_
26	levels	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	galectin	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	S1T	_	PROPN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	ATL	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1K	_	NUM	_	NumType=Card	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	lines	_	NOUN	_	Number=Plur	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	which	_	PRON	_	PronType=Rel	_	_	_	_
44	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
45	nonproductively	_	ADV	_	_	_	_	_	_
46	infected	_	VERB	_	Degree=Pos	_	_	_	_
47	with	_	ADP	_	_	_	_	_	_
48	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	co-transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	galectin	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	significantly	_	ADV	_	_	_	_	_	_
12	up	_	ADV	_	_	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	vectors	_	NOUN	_	Number=Plur	_	_	_	_
18	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	40	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kd	_	NOUN	_	Number=Sing	_	_	_	_
23	Tax	_	NOUN	_	Number=Sing	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	potent	_	NOUN	_	Degree=Pos	_	_	_	_
28	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	various	_	ADJ	_	Degree=Pos	_	_	_	_
4	Tax	_	NOUN	_	Number=Sing	_	_	_	_
5	mutants	_	NOUN	_	Number=Plur	_	_	_	_
6	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	galectin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cyclic	_	ADJ	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	AMP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
24	element	_	NOUN	_	Number=Sing	_	_	_	_
25	binding	_	VERB	_	Number=Sing	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	family	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	factors	_	NOUN	_	Number=Plur	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	lesser	_	ADJ	_	Degree=Cmp	_	_	_	_
40	extent	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
43	factor	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kappa	_	NOUN	_	Number=Sing	_	_	_	_
46	B	_	NOUN	_	Number=Sing	_	_	_	_
47	/	_	PUNCT	_	_	_	_	_	_
48	Rel	_	NOUN	_	Number=Sing	_	_	_	_
49	induction	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Transfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	promonocytic	_	ADJ	_	Number=Sing	_	_	_	_
5	U	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	937	_	NUM	_	NumType=Card	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	Tax	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	vector	_	NOUN	_	Number=Sing	_	_	_	_
17	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	galectin	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	line	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Functionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	galectin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	findings	_	NOUN	_	Number=Plur	_	_	_	_
5	raise	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	possibility	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	Tax	_	NOUN	_	Number=Sing	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
19	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	secretion	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	galectin	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	3	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	turn	_	NOUN	_	Number=Sing	_	_	_	_
30	may	_	AUX	_	VerbForm=Fin	_	_	_	_
31	further	_	ADV	_	_	_	_	_	_
32	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
33	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
34	T	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	properties	_	NOUN	_	Number=Plur	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	cell	_	NOUN	_	Number=Sing	_	_	_	_
44	growth	_	NOUN	_	Number=Sing	_	_	_	_
45	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	adult	_	NOUN	_	Number=Sing	_	_	_	_
48	T	_	NOUN	_	Number=Sing	_	_	_	_
49	cell	_	NOUN	_	Number=Sing	_	_	_	_
50	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
51	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
52	by	_	ADP	_	_	_	_	_	_
53	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002562	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Initiation	_	NOUN	_	Number=Sing	_	_	_	_
2	binding	_	VERB	_	Number=Sing	_	_	_	_
3	repressor	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	initiation	_	NOUN	_	Number=Sing	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	histone	_	NOUN	_	Number=Sing	_	_	_	_
17	h5	_	NUM	_	Degree=Pos	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	glycosylated	_	ADJ	_	Degree=Pos	_	_	_	_
23	member	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	family	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	growth	_	NOUN	_	Number=Sing	_	_	_	_
30	regulators	_	NOUN	_	Number=Plur	_	_	_	_
31	[	_	PUNCT	_	_	_	_	_	_
32	corrected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	]	_	PUNCT	_	_	_	_	_	_
34	[	_	PUNCT	_	_	_	_	_	_
35	published	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	erratum	_	NOUN	_	Number=Sing	_	_	_	_
37	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	Mol	_	NOUN	_	Number=Sing	_	_	_	_
40	Cell	_	NOUN	_	Number=Sing	_	_	_	_
41	Biol	_	NOUN	_	Number=Sing	_	_	_	_
42	1996	_	NUM	_	NumType=Card	_	_	_	_
43	Feb	_	PROPN	_	Number=Sing	_	_	_	_
44	;	_	PUNCT	_	_	_	_	_	_
45	16	_	NUM	_	NumType=Card	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	2):735	_	NUM	_	NumType=Card	_	_	_	_
48	]	_	PUNCT	_	_	_	_	_	_

1	Initiation	_	NOUN	_	Number=Sing	_	_	_	_
2	binding	_	VERB	_	Number=Sing	_	_	_	_
3	repressor	_	NOUN	_	Number=Sing	_	_	_	_
4	[	_	PUNCT	_	_	_	_	_	_
5	corrected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	]	_	PUNCT	_	_	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	IBR	_	X	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	chicken	_	NOUN	_	Number=Sing	_	_	_	_
13	erythrocyte	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
17	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
18	mass	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	70	_	NUM	_	NumType=Card	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	73	_	NUM	_	NumType=Card	_	_	_	_
23	kDa	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	sequences	_	NOUN	_	Number=Plur	_	_	_	_
30	spanning	_	VERB	_	VerbForm=Ger	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	initiation	_	NOUN	_	Number=Sing	_	_	_	_
34	site	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	histone	_	NOUN	_	Number=Sing	_	_	_	_
38	h5	_	NUM	_	Degree=Pos	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	repressing	_	VERB	_	VerbForm=Ger	_	_	_	_
42	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
43	transcription	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	variety	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	other	_	ADJ	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	including	_	VERB	_	VerbForm=Ger	_	_	_	_
8	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
10	precursors	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	have	_	VERB	_	VerbForm=Inf	_	_	_	_
15	IBR	_	PROPN	_	Number=Sing	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	referred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	IBF	_	PROPN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	68	_	NUM	_	NumType=Card	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	70	_	NUM	_	NumType=Card	_	_	_	_
27	kDa	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	same	_	ADJ	_	Degree=Pos	_	_	_	_
33	IBR	_	NOUN	_	Number=Sing	_	_	_	_
34	sites	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	IBR	_	PROPN	_	Number=Sing	_	_	_	_
6	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	relationship	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	IBR	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	IBF	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	IBR	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	503	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	amino	_	ADJ	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	acid	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	long	_	ADJ	_	Degree=Pos	_	_	_	_
11	acidic	_	ADJ	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	99.0	_	NUM	_	NumType=Card	_	_	_	_
16	%	_	SYM	_	Number=Sing	_	_	_	_
17	identical	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	recently	_	ADV	_	_	_	_	_	_
21	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	NRF	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1/alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	Pal	_	NOUN	_	Number=Sing	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	highly	_	ADV	_	_	_	_	_	_
31	related	_	ADJ	_	Degree=Pos	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	invertebrate	_	ADJ	_	Degree=Pos	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	factors	_	NOUN	_	Number=Plur	_	_	_	_
37	P3A2	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	erected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	wing	_	NOUN	_	Number=Sing	_	_	_	_
41	gene	_	NOUN	_	Number=Sing	_	_	_	_
42	product	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	EWG	_	PROPN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	present	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	evidence	_	NOUN	_	Number=Sing	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IBR	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	IBF	_	PROPN	_	Number=Sing	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	most	_	ADV	_	_	_	_	_	_
10	likely	_	ADV	_	Degree=Pos	_	_	_	_
11	identical	_	ADJ	_	Degree=Pos	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	differing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	degree	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	glycosylation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	several	_	ADJ	_	Degree=Pos	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	aspects	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IBR	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	F	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	associates	_	VERB	_	Number=Plur	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	stable	_	ADJ	_	Degree=Pos	_	_	_	_
19	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	dimer	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
27	DNA	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	species	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	evolutionarily	_	ADV	_	_	_	_	_	_
3	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	N	_	ADJ	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	terminal	_	ADJ	_	Number=Sing	_	_	_	_
7	half	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IBR	_	PROPN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	F	_	PROPN	_	Number=Sing	_	_	_	_
12	harbors	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	DNA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	dimerization	_	NOUN	_	Number=Sing	_	_	_	_
19	domain	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	outer	_	ADJ	_	Degree=Pos	_	_	_	_
22	limits	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	127	_	NUM	_	NumType=Card	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	283	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	one	_	NUM	_	NumType=Card	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	several	_	ADJ	_	Degree=Pos	_	_	_	_
32	casein	_	NOUN	_	Number=Sing	_	_	_	_
33	kinase	_	NOUN	_	Number=Sing	_	_	_	_
34	II	_	NUM	_	NumType=Card	_	_	_	_
35	sites	_	NOUN	_	Number=Plur	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	37	_	NUM	_	NumType=Card	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	67	_	NUM	_	NumType=Card	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	bipartite	_	ADJ	_	Degree=Pos	_	_	_	_
45	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
46	localization	_	NOUN	_	Number=Sing	_	_	_	_
47	signal	_	NOUN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	89	_	NUM	_	NumType=Card	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	106	_	NUM	_	NumType=Card	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	which	_	PRON	_	PronType=Rel	_	_	_	_
54	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
55	to	_	PART	_	_	_	_	_	_
56	be	_	AUX	_	VerbForm=Inf	_	_	_	_
57	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
58	for	_	ADP	_	_	_	_	_	_
59	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
60	targeting	_	NOUN	_	Number=Sing	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	site	_	NOUN	_	Number=Sing	_	_	_	_
3	selection	_	NOUN	_	Number=Sing	_	_	_	_
4	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	alternating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	RCGCRYGCGY	_	PROPN	_	Number=Sing	_	_	_	_
9	consensus	_	NOUN	_	Number=Sing	_	_	_	_
10	constitutes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	high	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	affinity	_	NOUN	_	Number=Sing	_	_	_	_
14	IBR	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	F	_	ADP	_	Number=Sing	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	direct	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	repeat	_	VERB	_	Degree=Pos	_	_	_	_
25	palindrome	_	NOUN	_	Number=Sing	_	_	_	_
26	TGCGCATGCGCA	_	PROPN	_	Number=Sing	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
30	site	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	survey	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	genes	_	NOUN	_	Number=Plur	_	_	_	_
5	potentially	_	ADV	_	_	_	_	_	_
6	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	family	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	primarily	_	ADV	_	_	_	_	_	_
13	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	involved	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	growth	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	related	_	ADJ	_	Degree=Pos	_	_	_	_
20	metabolism	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002564	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Apoptosis	_	PROPN	_	Number=Sing	_	_	_	_
2	signaling	_	VERB	_	Number=Sing	_	_	_	_
3	pathways	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	normal	_	ADJ	_	Degree=Pos	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	differential	_	ADJ	_	Degree=Pos	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1beta	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	converting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	enzyme	_	NOUN	_	Degree=Pos	_	_	_	_
22	family	_	NOUN	_	Number=Sing	_	_	_	_
23	protease	_	NOUN	_	Number=Sing	_	_	_	_
24	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	Fas	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
32	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Fas	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	important	_	ADJ	_	Degree=Pos	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	SCONJ	_	_	_	_	_	_
10	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	immune	_	ADJ	_	Degree=Pos	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Restimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	blasts	_	NOUN	_	Number=Plur	_	_	_	_
6	up	_	NOUN	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	regulates	_	VERB	_	Number=Plur	_	_	_	_
9	Fas	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	Fas	_	NOUN	_	Number=Sing	_	_	_	_
12	ligand	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
17	interaction	_	NOUN	_	Number=Sing	_	_	_	_
18	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	death	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	tumor	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	blocks	_	NOUN	_	Number=Plur	_	_	_	_
10	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	many	_	ADJ	_	Degree=Pos	_	_	_	_
14	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	Fas	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
22	killing	_	NOUN	_	Number=Sing	_	_	_	_
23	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	consistently	_	ADV	_	_	_	_	_	_
27	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	behavior	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	normal	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	blasts	_	NOUN	_	Number=Plur	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	transiently	_	ADV	_	_	_	_	_	_
18	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	related	_	ADJ	_	Degree=Pos	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	products	_	NOUN	_	Number=Plur	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	effect	_	NOUN	_	Number=Sing	_	_	_	_
31	on	_	ADP	_	_	_	_	_	_
32	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
33	signaling	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	mouse	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	blasts	_	NOUN	_	Number=Plur	_	_	_	_
14	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	block	_	VERB	_	VerbForm=Inf	_	_	_	_
17	Fas	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	whereas	_	SCONJ	_	_	_	_	_	_
23	etoposide	_	ADJ	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
30	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
31	potently	_	ADV	_	_	_	_	_	_
32	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	xL	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	adenovirus	_	ADJ	_	Number=Sing	_	_	_	_
8	E1B	_	PROPN	_	Number=Sing	_	_	_	_
9	19	_	NUM	_	NumType=Card	_	_	_	_
10	K	_	NUM	_	Number=Sing	_	_	_	_
11	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	interfere	_	VERB	_	VerbForm=Inf	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	anti-Fas	_	NOUN	_	Degree=Pos	_	_	_	_
16	killing	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	interleukin	_	ADJ	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1beta	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	converting	_	VERB	_	VerbForm=Ger	_	_	_	_
9	enzyme	_	NOUN	_	Degree=Pos	_	_	_	_
10	family	_	NOUN	_	Number=Sing	_	_	_	_
11	protease	_	NOUN	_	Number=Sing	_	_	_	_
12	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
13	Ac-DEVD	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	CHO	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	CrmA	_	PROPN	_	Number=Sing	_	_	_	_
18	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	Fas	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	use	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
10	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
11	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
12	pathways	_	NOUN	_	Number=Plur	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	differential	_	ADJ	_	Degree=Pos	_	_	_	_
15	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	interleukin	_	ADJ	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1beta	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	converting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	enzyme	_	NOUN	_	Degree=Pos	_	_	_	_
27	family	_	NOUN	_	Number=Sing	_	_	_	_
28	protease	_	NOUN	_	Number=Sing	_	_	_	_
29	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	normally	_	ADV	_	_	_	_	_	_
5	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	xL	_	PROPN	_	Number=Sing	_	_	_	_
13	following	_	VERB	_	VerbForm=Ger	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	inability	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	block	_	VERB	_	VerbForm=Inf	_	_	_	_
20	Fas	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
23	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
24	may	_	AUX	_	VerbForm=Fin	_	_	_	_
25	allow	_	VERB	_	VerbForm=Inf	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	elimination	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	self	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	appropriate	_	ADJ	_	Degree=Pos	_	_	_	_
37	regulation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	immune	_	ADJ	_	Degree=Pos	_	_	_	_
40	responses	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002565	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
4	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	like	_	ADJ	_	Degree=Pos	_	_	_	_
12	activities	_	NOUN	_	Number=Plur	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	infection	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	myelomonoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	infection	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	DNA	_	NOUN	_	Number=Sing	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
27	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	new	_	ADJ	_	Degree=Pos	_	_	_	_
31	model	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
34	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	PLB	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	985	_	NUM	_	NumType=Card	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	represent	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	bipotential	_	ADJ	_	Degree=Pos	_	_	_	_
8	myelomonoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	population	_	NOUN	_	Number=Sing	_	_	_	_
11	capable	_	ADJ	_	Degree=Pos	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	either	_	CCONJ	_	_	_	_	_	_
14	granulocytic	_	ADJ	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	after	_	ADP	_	_	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	appropriate	_	ADJ	_	Degree=Pos	_	_	_	_
22	inducers	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	virtue	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	presence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CD4	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	surface	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	PLB	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	985	_	NUM	_	NumType=Card	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	chronically	_	ADV	_	_	_	_	_	_
19	infected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	HIV	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	strain	_	NOUN	_	Number=Sing	_	_	_	_
25	IIIB	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	PLB	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	IIIB	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	clearly	_	ADV	_	_	_	_	_	_
6	possessed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	more	_	ADJ	_	_	_	_	_	_
9	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
11	than	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	parental	_	ADJ	_	Degree=Pos	_	_	_	_
14	myeloblasts	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	as	_	SCONJ	_	_	_	_	_	_
17	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	differential	_	ADJ	_	Degree=Pos	_	_	_	_
20	staining	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	myeloid	_	ADJ	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	specific	_	ADJ	_	Degree=Pos	_	_	_	_
29	surface	_	NOUN	_	Number=Sing	_	_	_	_
30	markers	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	c-fms	_	NOUN	_	Number=Plur	_	_	_	_
37	proto	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	tumor	_	NOUN	_	Number=Sing	_	_	_	_
11	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
15	myristate	_	NOUN	_	Number=Sing	_	_	_	_
16	acetate	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	PLB	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	985	_	NUM	_	NumType=Card	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	PLB	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	IIIB	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	novel	_	NOUN	_	Number=Sing	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	complex	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	composed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	proteins	_	NOUN	_	Number=Plur	_	_	_	_
25	ranging	_	VERB	_	VerbForm=Ger	_	_	_	_
26	between	_	ADP	_	_	_	_	_	_
27	70	_	NUM	_	NumType=Card	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	110	_	NUM	_	NumType=Card	_	_	_	_
30	kD	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	proteins	_	NOUN	_	Number=Plur	_	_	_	_
3	interacted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	specifically	_	ADV	_	_	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	symmetric	_	ADJ	_	Degree=Pos	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	interferon	_	NOUN	_	Number=Sing	_	_	_	_
16	beta	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	IFN	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	beta	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	5	_	NUM	_	NumType=Card	_	_	_	_
5	'	_	PUNCT	_	_	_	_	_	_
6	guanine	_	NOUN	_	Number=Sing	_	_	_	_
7	residues	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	unable	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	compete	_	VERB	_	VerbForm=Inf	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	related	_	ADJ	_	Degree=Pos	_	_	_	_
25	proteins	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Inducibility	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
4	IFN	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	IFN	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	PROPN	_	Number=Sing	_	_	_	_
11	RNA	_	PROPN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	PLB	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	IIIB	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	infection	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	myelomonoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	select	_	VERB	_	VerbForm=Inf	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	more	_	ADV	_	_	_	_	_	_
17	mature	_	ADJ	_	Degree=Pos	_	_	_	_
18	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	that	_	DET	_	_	_	_	_	_
22	unique	_	ADJ	_	Degree=Pos	_	_	_	_
23	subunit	_	NOUN	_	Number=Sing	_	_	_	_
24	associations	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	DNA	_	NOUN	_	Number=Sing	_	_	_	_
31	binding	_	VERB	_	Number=Sing	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	may	_	AUX	_	VerbForm=Fin	_	_	_	_
34	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	differential	_	ADJ	_	Degree=Pos	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kappa	_	NOUN	_	Number=Sing	_	_	_	_
40	B	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
43	gene	_	NOUN	_	Number=Sing	_	_	_	_
44	expression	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002567	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	stably	_	ADV	_	_	_	_	_	_
10	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	Tax	_	NOUN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lymphotropic	_	ADJ	_	Degree=Pos	_	_	_	_
19	virus	_	NOUN	_	Number=Sing	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
5	Tax	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	interaction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	recognition	_	NOUN	_	Number=Sing	_	_	_	_
18	sequence	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	T	_	PROPN	_	Number=Sing	_	_	_	_
33	lymphoid	_	PROPN	_	Number=Sing	_	_	_	_
34	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	lines	_	NOUN	_	Number=Plur	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	19D	_	NUM	_	NumType=Card	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	9J	_	PROPN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	stably	_	ADV	_	_	_	_	_	_
43	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	with	_	ADP	_	_	_	_	_	_
45	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
46	Tax	_	NOUN	_	Number=Sing	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	vector	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	expressing	_	NOUN	_	Number=Sing	_	_	_	_

1	T	_	NUM	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
7	level	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	detectable	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	mobility	_	NOUN	_	Number=Sing	_	_	_	_
19	shift	_	NOUN	_	Number=Sing	_	_	_	_
20	assay	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	uv	_	PROPN	_	Number=Sing	_	_	_	_
23	cross	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
26	using	_	VERB	_	VerbForm=Ger	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	palindromic	_	ADJ	_	Degree=Pos	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	probe	_	NOUN	_	Number=Sing	_	_	_	_
34	homologous	_	ADJ	_	Number=Sing	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	interferon	_	NOUN	_	Number=Sing	_	_	_	_
38	beta	_	NOUN	_	Number=Sing	_	_	_	_
39	PRDII	_	NOUN	_	Number=Sing	_	_	_	_
40	site	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	NC2.10	_	PROPN	_	Number=Sing	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
8	esters	_	NOUN	_	Number=Plur	_	_	_	_
9	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	appearance	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	new	_	ADJ	_	Degree=Pos	_	_	_	_
15	DNA	_	PROPN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	85	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	75	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	54	_	NUM	_	NumType=Card	_	_	_	_
25	kDa	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	whereas	_	SCONJ	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	Tax	_	NOUN	_	Number=Sing	_	_	_	_
30	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	85	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kDa	_	NOUN	_	Number=Sing	_	_	_	_
36	protein	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	92	_	NUM	_	NumType=Card	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kDa	_	NOUN	_	Number=Sing	_	_	_	_
42	DNA	_	NOUN	_	Number=Sing	_	_	_	_
43	binding	_	NOUN	_	Number=Sing	_	_	_	_
44	protein	_	NOUN	_	Number=Sing	_	_	_	_
45	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
46	constitutively	_	ADV	_	_	_	_	_	_
47	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Tax	_	NOUN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	19D	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	9J	_	NOUN	_	Number=Sing	_	_	_	_
9	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
21	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
24	colony	_	NOUN	_	Number=Sing	_	_	_	_
25	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	basal	_	ADJ	_	Degree=Pos	_	_	_	_
31	level	_	NOUN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	promoters	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Nonetheless	_	ADV	_	_	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transfected	_	VERB	_	Degree=Pos	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	inducible	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	PMA	_	NOUN	_	Number=Sing	_	_	_	_
15	treatment	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	stoichiometry	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	thus	_	ADV	_	_	_	_	_	_
21	change	_	VERB	_	VerbForm=Inf	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	promoters	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002568	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	characterization	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	component	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	body	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	body	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	NB	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	organelle	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	involved	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	acute	_	ADJ	_	Degree=Pos	_	_	_	_
19	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
20	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	viral	_	ADJ	_	Degree=Pos	_	_	_	_
23	infection	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NB	_	PROPN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	target	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	serum	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	patients	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	autoimmune	_	NOUN	_	Number=Sing	_	_	_	_
17	disease	_	NOUN	_	Number=Sing	_	_	_	_
18	primary	_	ADJ	_	Degree=Pos	_	_	_	_
19	biliary	_	NOUN	_	Number=Sing	_	_	_	_
20	cirrhosis	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	serum	_	NOUN	_	Number=Sing	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	patient	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	primary	_	ADJ	_	Degree=Pos	_	_	_	_
11	biliary	_	NOUN	_	Number=Sing	_	_	_	_
12	cirrhosis	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
19	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	novel	_	NOUN	_	Number=Sing	_	_	_	_
22	component	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	NB	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	140	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kDa	_	NOUN	_	Number=Sing	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	Sp140	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	predicted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	amino	_	NOUN	_	Number=Sing	_	_	_	_
4	acid	_	VERB	_	Number=Sing	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	amino	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
11	portion	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Sp140	_	PROPN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	similar	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	Sp100	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	previously	_	ADV	_	_	_	_	_	_
21	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	NB	_	PROPN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	carboxyl	_	ADJ	_	Number=Sing	_	_	_	_
3	portion	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Sp140	_	PROPN	_	Number=Sing	_	_	_	_
6	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	zinc	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	finger	_	NOUN	_	Number=Sing	_	_	_	_
11	domain	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	bromodomain	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	motifs	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	present	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	High	_	ADJ	_	Degree=Pos	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Sp140	_	PROPN	_	Number=Sing	_	_	_	_
5	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	spleen	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
13	blood	_	NOUN	_	Number=Sing	_	_	_	_
14	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	not	_	ADV	_	_	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	tissues	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	level	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	SP140	_	PROPN	_	Number=Sing	_	_	_	_
5	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
8	precursor	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	lines	_	NOUN	_	Number=Plur	_	_	_	_
11	HL60	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	NB4	_	PROPN	_	Number=Sing	_	_	_	_
14	markedly	_	ADV	_	_	_	_	_	_
15	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	chemically	_	ADV	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Immunohistochemical	_	ADJ	_	Degree=Pos	_	_	_	_
2	techniques	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	demonstrate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	SP140	_	NOUN	_	Number=Sing	_	_	_	_
9	localized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	NB	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
15	HL60	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	NB4	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	location	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Sp140	_	PROPN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	NB	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	involved	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	host	_	NOUN	_	Number=Sing	_	_	_	_
19	defense	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	Sp140	_	NOUN	_	Number=Sing	_	_	_	_
24	may	_	AUX	_	VerbForm=Fin	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	involved	_	ADJ	_	Degree=Pos	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	acute	_	ADJ	_	Degree=Pos	_	_	_	_
32	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
33	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	viral	_	ADJ	_	Degree=Pos	_	_	_	_
36	infection	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002570	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	pp90rsk	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	early	_	ADJ	_	Degree=Pos	_	_	_	_
6	growth	_	NOUN	_	Number=Sing	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	pokeweed	_	VERB	_	Degree=Pos	_	_	_	_
14	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	pokeweed	_	NOUN	_	Number=Sing	_	_	_	_
10	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	PWM	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	early	_	ADJ	_	Degree=Pos	_	_	_	_
19	growth	_	NOUN	_	Number=Sing	_	_	_	_
20	response	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	EGR	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	X	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	normal	_	ADJ	_	Degree=Pos	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	PWM	_	PROPN	_	Number=Sing	_	_	_	_
2	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	EGR	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	post	_	NOUN	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	assays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	EGR	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	fragments	_	NOUN	_	Number=Plur	_	_	_	_
10	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	chloramphenicol	_	PROPN	_	Number=Sing	_	_	_	_
14	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	CAT	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	PWM	_	PROPN	_	Number=Sing	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	EGR	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	conferred	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	CArG	_	PROPN	_	Number=Sing	_	_	_	_
32	motif	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	C	_	NOUN	_	Number=Sing	_	_	_	_
35	C	_	NOUN	_	Number=Sing	_	_	_	_
36	[	_	PUNCT	_	_	_	_	_	_
37	AT	_	ADP	_	_	_	_	_	_
38	]	_	PUNCT	_	_	_	_	_	_
39	6	_	NUM	_	NumType=Card	_	_	_	_
40	GG	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	EGR	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	promoter	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	further	_	ADV	_	_	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	S6	_	NUM	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	pp90rsk	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	evidenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	S6	_	PROPN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	serum	_	NOUN	_	Number=Sing	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	SRF	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	peptides	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	PWM	_	NOUN	_	Number=Sing	_	_	_	_
30	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	B	_	ADJ	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	findings	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	PWM	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	able	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	intracytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
15	signalling	_	NOUN	_	Number=Sing	_	_	_	_
16	cascade	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	EGR	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	induction	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	normal	_	ADJ	_	Degree=Pos	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002578	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Autoregulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
9	RelA	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	p65	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
15	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
16	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
17	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	ankyrin	_	ADJ	_	Number=Sing	_	_	_	_
19	motifs	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	RelA	_	NOUN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	p65	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	functions	_	NOUN	_	Number=Plur	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	critical	_	ADJ	_	Degree=Pos	_	_	_	_
9	transactivating	_	NOUN	_	Number=Sing	_	_	_	_
10	component	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	heterodimeric	_	PROPN	_	Degree=Pos	_	_	_	_
14	p50-p65	_	NUM	_	Number=Sing	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	complex	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	high	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	affinity	_	NOUN	_	Number=Sing	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	site	_	NOUN	_	Number=Sing	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
30	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
31	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
34	kappa	_	VERB	_	Number=Sing	_	_	_	_
35	B	_	PROPN	_	Number=Sing	_	_	_	_
36	alpha	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	kappa	_	VERB	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	rapidly	_	ADV	_	_	_	_	_	_
11	degraded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	concert	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	translocation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	PROPN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	tumor	_	NOUN	_	Number=Sing	_	_	_	_
7	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	degradation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	kappa	_	VERB	_	Number=Sing	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	preceded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	vivo	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	kappa	_	VERB	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	result	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	only	_	ADV	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	fraction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	entire	_	ADJ	_	Degree=Pos	_	_	_	_
21	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
22	pool	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	RelA	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	i	_	X	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
10	RelA	_	PROPN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	stably	_	ADV	_	_	_	_	_	_
13	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	only	_	ADV	_	_	_	_	_	_
16	with	_	SCONJ	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	also	_	ADV	_	_	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	other	_	ADJ	_	Degree=Pos	_	_	_	_
25	ankyrin	_	ADJ	_	Number=Sing	_	_	_	_
26	motif	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	rich	_	ADJ	_	Degree=Pos	_	_	_	_
29	proteins	_	NOUN	_	Number=Plur	_	_	_	_
30	including	_	VERB	_	VerbForm=Ger	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	products	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B2	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	p100	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	NF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kappa	_	PROPN	_	Number=Sing	_	_	_	_
46	B1	_	PROPN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	p105	_	NOUN	_	NumType=Card	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	genes	_	NOUN	_	Number=Plur	_	_	_	_
51	;	_	PUNCT	_	_	_	_	_	_
52	(	_	PUNCT	_	_	_	_	_	_
53	ii	_	X	_	_	_	_	_	_
54	)	_	PUNCT	_	_	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	contrast	_	NOUN	_	Number=Sing	_	_	_	_
57	to	_	ADP	_	_	_	_	_	_
58	RelA	_	PROPN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
61	kappa	_	VERB	_	Number=Sing	_	_	_	_
62	B	_	PROPN	_	Number=Sing	_	_	_	_
63	alpha	_	NOUN	_	Number=Sing	_	_	_	_
64	,	_	PUNCT	_	_	_	_	_	_
65	RelA	_	PROPN	_	Number=Sing	_	_	_	_
66	-	_	PUNCT	_	_	_	_	_	_
67	p100	_	PROPN	_	Number=Sing	_	_	_	_
68	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
69	complexes	_	NOUN	_	Number=Plur	_	_	_	_
70	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
71	not	_	PART	_	_	_	_	_	_
72	dissociated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
73	following	_	VERB	_	VerbForm=Ger	_	_	_	_
74	tumor	_	NOUN	_	Number=Sing	_	_	_	_
75	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
76	factor	_	NOUN	_	Number=Sing	_	_	_	_
77	alpha	_	NOUN	_	Number=Sing	_	_	_	_
78	activation	_	NOUN	_	Number=Sing	_	_	_	_
79	;	_	PUNCT	_	_	_	_	_	_
80	(	_	PUNCT	_	_	_	_	_	_
81	iii	_	X	_	_	_	_	_	_
82	)	_	PUNCT	_	_	_	_	_	_
83	p100	_	NOUN	_	Number=Sing	_	_	_	_
84	functions	_	NOUN	_	Number=Plur	_	_	_	_
85	as	_	ADP	_	_	_	_	_	_
86	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
87	potent	_	ADJ	_	Degree=Pos	_	_	_	_
88	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
89	of	_	ADP	_	_	_	_	_	_
90	RelA	_	ADJ	_	Number=Sing	_	_	_	_
91	-	_	PUNCT	_	_	_	_	_	_
92	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
93	transcription	_	NOUN	_	Number=Sing	_	_	_	_
94	in	_	ADP	_	_	_	_	_	_
95	vivo	_	NOUN	_	Number=Sing	_	_	_	_
96	;	_	PUNCT	_	_	_	_	_	_
97	(	_	PUNCT	_	_	_	_	_	_
98	iv	_	X	_	Number=Sing	_	_	_	_
99	)	_	PUNCT	_	_	_	_	_	_
100	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
101	interaction	_	NOUN	_	Number=Sing	_	_	_	_
102	of	_	ADP	_	_	_	_	_	_
103	RelA	_	NOUN	_	Number=Sing	_	_	_	_
104	and	_	CCONJ	_	_	_	_	_	_
105	p100	_	NOUN	_	Number=Sing	_	_	_	_
106	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
107	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
108	conserved	_	VERB	_	Degree=Pos	_	_	_	_
109	Rel	_	NOUN	_	Number=Sing	_	_	_	_
110	homology	_	NOUN	_	Number=Sing	_	_	_	_
111	domain	_	NOUN	_	Number=Sing	_	_	_	_
112	of	_	ADP	_	_	_	_	_	_
113	both	_	DET	_	_	_	_	_	_
114	proteins	_	NOUN	_	Number=Plur	_	_	_	_
115	but	_	CCONJ	_	_	_	_	_	_
116	not	_	PART	_	_	_	_	_	_
117	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
118	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
119	localization	_	NOUN	_	Number=Sing	_	_	_	_
120	signal	_	NOUN	_	Number=Sing	_	_	_	_
121	of	_	ADP	_	_	_	_	_	_
122	RelA	_	NOUN	_	Number=Sing	_	_	_	_
123	,	_	PUNCT	_	_	_	_	_	_
124	which	_	PRON	_	PronType=Rel	_	_	_	_
125	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
126	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
127	for	_	SCONJ	_	_	_	_	_	_
128	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
129	kappa	_	VERB	_	Number=Sing	_	_	_	_
130	B	_	PROPN	_	Number=Sing	_	_	_	_
131	alpha	_	PROPN	_	Number=Sing	_	_	_	_
132	binding	_	NOUN	_	Number=Sing	_	_	_	_
133	;	_	PUNCT	_	_	_	_	_	_
134	(	_	PUNCT	_	_	_	_	_	_
135	v	_	NOUN	_	Number=Sing	_	_	_	_
136	)	_	PUNCT	_	_	_	_	_	_
137	p100	_	NUM	_	NumType=Card	_	_	_	_
138	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
139	of	_	ADP	_	_	_	_	_	_
140	RelA	_	ADJ	_	Number=Sing	_	_	_	_
141	function	_	NOUN	_	Number=Sing	_	_	_	_
142	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
143	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
144	C	_	NOUN	_	Number=Sing	_	_	_	_
145	-	_	PUNCT	_	_	_	_	_	_
146	terminal	_	NOUN	_	Number=Sing	_	_	_	_
147	ankyrin	_	NOUN	_	Number=Sing	_	_	_	_
148	motif	_	NOUN	_	Number=Sing	_	_	_	_
149	domain	_	NOUN	_	Number=Sing	_	_	_	_
150	,	_	PUNCT	_	_	_	_	_	_
151	which	_	PRON	_	PronType=Rel	_	_	_	_
152	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
153	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
154	retention	_	NOUN	_	Number=Sing	_	_	_	_
155	of	_	ADP	_	_	_	_	_	_
156	RelA	_	NOUN	_	Number=Sing	_	_	_	_
157	;	_	PUNCT	_	_	_	_	_	_
158	and	_	CCONJ	_	_	_	_	_	_
159	(	_	PUNCT	_	_	_	_	_	_
160	vi	_	X	_	Number=Sing	_	_	_	_
161	)	_	PUNCT	_	_	_	_	_	_
162	as	_	SCONJ	_	_	_	_	_	_
163	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
164	with	_	ADP	_	_	_	_	_	_
165	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
166	kappa	_	VERB	_	Number=Sing	_	_	_	_
167	B	_	PROPN	_	Number=Sing	_	_	_	_
168	alpha	_	NOUN	_	Number=Sing	_	_	_	_
169	,	_	PUNCT	_	_	_	_	_	_
170	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
171	RelA	_	PROPN	_	Number=Sing	_	_	_	_
172	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
173	p100	_	NUM	_	Number=Sing	_	_	_	_
174	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
175	and	_	CCONJ	_	_	_	_	_	_
176	protein	_	NOUN	_	Number=Sing	_	_	_	_
177	expression	_	NOUN	_	Number=Sing	_	_	_	_
178	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	thus	_	ADV	_	_	_	_	_	_
4	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	presence	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
10	inducible	_	ADJ	_	Number=Sing	_	_	_	_
11	autoregulated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
12	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
13	pathway	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	helps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	ensure	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	transient	_	ADJ	_	Degree=Pos	_	_	_	_
21	action	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B.	_	PROPN	_	Number=Sing	_	_	_	_
28	Document	_	NOUN	_	Number=Sing	_	_	_	_
29	003002582	_	NUM	_	NumType=Card	_	_	_	_
30	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	interaction	_	NOUN	_	Number=Sing	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	zinc	_	NOUN	_	Number=Sing	_	_	_	_
7	finger	_	NOUN	_	Number=Sing	_	_	_	_
8	domains	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	v-erb	_	NOUN	_	Degree=Pos	_	_	_	_
12	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	v-erb	_	NOUN	_	Number=Sing	_	_	_	_
3	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	avian	_	ADJ	_	Degree=Pos	_	_	_	_
7	erythroblastosis	_	NOUN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	mutated	_	VERB	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	virally	_	ADV	_	_	_	_	_	_
14	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	copy	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	host	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
24	hormone	_	NOUN	_	Number=Sing	_	_	_	_
25	receptor	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	v-erb	_	NOUN	_	Number=Sing	_	_	_	_
7	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
9	binds	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	acts	_	VERB	_	Number=Plur	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
17	negative	_	ADJ	_	Degree=Pos	_	_	_	_
18	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
23	hormone	_	NOUN	_	Number=Sing	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	closely	_	ADV	_	_	_	_	_	_
28	related	_	ADJ	_	Degree=Pos	_	_	_	_
29	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
30	acid	_	NOUN	_	Number=Sing	_	_	_	_
31	receptor	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	v-erb	_	NOUN	_	Number=Sing	_	_	_	_
3	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	amino	_	NOUN	_	Degree=Pos	_	_	_	_
9	acid	_	VERB	_	Number=Sing	_	_	_	_
10	alterations	_	NOUN	_	Number=Plur	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	domain	_	NOUN	_	Number=Sing	_	_	_	_
17	relative	_	ADV	_	_	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	c	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	erb	_	PROPN	_	Number=Sing	_	_	_	_
24	A	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	one	_	NUM	_	NumType=Card	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Int	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	at	_	ADP	_	_	_	_	_	_
31	serine	_	NOUN	_	Number=Sing	_	_	_	_
32	61	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	be	_	AUX	_	VerbForm=Inf	_	_	_	_
38	important	_	ADJ	_	Degree=Pos	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	v	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	erb	_	NOUN	_	Number=Sing	_	_	_	_
43	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	function	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	neoplastic	_	ADJ	_	Degree=Pos	_	_	_	_
48	cell	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	alteration	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	threonine	_	PROPN	_	Number=Sing	_	_	_	_
11	78	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	important	_	ADJ	_	Degree=Pos	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	although	_	SCONJ	_	_	_	_	_	_
19	more	_	ADV	_	_	_	_	_	_
20	indirect	_	ADJ	_	Degree=Pos	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	:	_	PUNCT	_	_	_	_	_	_
24	alteration	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	sequence	_	NOUN	_	Number=Sing	_	_	_	_
28	at	_	ADP	_	_	_	_	_	_
29	threonine	_	PROPN	_	Number=Sing	_	_	_	_
30	78	_	NUM	_	NumType=Card	_	_	_	_
31	such	_	ADJ	_	Degree=Pos	_	_	_	_
32	that	_	SCONJ	_	_	_	_	_	_
33	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
34	resembles	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	c	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	erb	_	PROPN	_	Number=Sing	_	_	_	_
40	A	_	PROPN	_	Number=Sing	_	_	_	_
41	can	_	AUX	_	VerbForm=Fin	_	_	_	_
42	act	_	VERB	_	VerbForm=Inf	_	_	_	_
43	as	_	ADP	_	_	_	_	_	_
44	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
45	intragenic	_	ADJ	_	Degree=Pos	_	_	_	_
46	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	can	_	AUX	_	VerbForm=Fin	_	_	_	_
49	partially	_	ADV	_	_	_	_	_	_
50	restore	_	VERB	_	VerbForm=Inf	_	_	_	_
51	function	_	NOUN	_	Number=Sing	_	_	_	_
52	to	_	ADP	_	_	_	_	_	_
53	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
54	v	_	NOUN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	erb	_	NOUN	_	Number=Sing	_	_	_	_
57	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
58	protein	_	NOUN	_	Number=Sing	_	_	_	_
59	rendered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
60	defective	_	NOUN	_	Number=Sing	_	_	_	_
61	due	_	ADP	_	_	_	_	_	_
62	to	_	ADP	_	_	_	_	_	_
63	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
64	mutation	_	NOUN	_	Number=Sing	_	_	_	_
65	at	_	ADP	_	_	_	_	_	_
66	position	_	NOUN	_	Number=Sing	_	_	_	_
67	61	_	NUM	_	NumType=Card	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	Threonine	_	PROPN	_	Number=Sing	_	_	_	_
2	78	_	NUM	_	NumType=Card	_	_	_	_
3	lies	_	NOUN	_	Number=Plur	_	_	_	_
4	within	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	D	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	box	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	v-erb	_	NOUN	_	Number=Sing	_	_	_	_
12	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	thought	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	dimerizations	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	physical	_	ADJ	_	Degree=Pos	_	_	_	_
30	proximity	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	serine	_	NOUN	_	Number=Sing	_	_	_	_
34	at	_	ADP	_	_	_	_	_	_
35	position	_	NOUN	_	Number=Sing	_	_	_	_
36	61	_	NUM	_	NumType=Card	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	indirect	_	ADJ	_	Degree=Pos	_	_	_	_
7	interaction	_	NOUN	_	Number=Sing	_	_	_	_
8	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	two	_	NUM	_	NumType=Card	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	interaction	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	v-erb	_	ADJ	_	_	_	_	_	_
21	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	function	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002583	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
4	development	_	NOUN	_	Number=Sing	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
5	maturation	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	family	_	NOUN	_	Number=Sing	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	long	_	ADV	_	Degree=Pos	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	suspected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	yet	_	ADV	_	_	_	_	_	_
22	proven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mice	_	NOUN	_	Number=Plur	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	defect	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
3	cellularity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	mice	_	NOUN	_	Number=Plur	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	significantly	_	ADV	_	_	_	_	_	_
9	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	proportion	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	mature	_	ADJ	_	Degree=Pos	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	TCRhigh	_	ADJ	_	Degree=Pos	_	_	_	_
7	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	alphabeta	_	NOUN	_	Number=Sing	_	_	_	_
11	lineage	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	remaining	_	ADJ	_	VerbForm=Ger	_	_	_	_
18	TCRhigh	_	ADJ	_	Degree=Pos	_	_	_	_
19	population	_	NOUN	_	Number=Sing	_	_	_	_
20	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	unusually	_	ADV	_	_	_	_	_	_
23	high	_	ADJ	_	Degree=Pos	_	_	_	_
24	proportion	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	double	_	ADJ	_	Degree=Pos	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	positive	_	ADJ	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	defect	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	maturation	_	NOUN	_	Number=Sing	_	_	_	_
5	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	transgene	_	NOUN	_	Number=Sing	_	_	_	_
9	dose	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	reduction	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	with	_	SCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	CD8	_	PROPN	_	Number=Sing	_	_	_	_
21	lineage	_	NOUN	_	Number=Sing	_	_	_	_
22	being	_	AUX	_	VerbForm=Ger	_	_	_	_
23	more	_	ADV	_	_	_	_	_	_
24	severely	_	ADV	_	_	_	_	_	_
25	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	direct	_	ADJ	_	Degree=Pos	_	_	_	_
5	evidence	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	involvement	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	Rel	_	PROPN	_	Number=Sing	_	_	_	_
15	family	_	NOUN	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	late	_	ADJ	_	Degree=Pos	_	_	_	_
19	stages	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
23	development	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	coincident	_	ADJ	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	positive	_	ADJ	_	Degree=Pos	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	negative	_	ADJ	_	Degree=Pos	_	_	_	_
30	selection	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002587	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	belonging	_	VERB	_	VerbForm=Ger	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	rel	_	PROPN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	PROPN	_	Number=Sing	_	_	_	_
14	family	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	transdominant	_	ADJ	_	Degree=Pos	_	_	_	_
18	negative	_	ADJ	_	Degree=Pos	_	_	_	_
19	mutant	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	KBF1	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
10	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	mouse	_	NOUN	_	Number=Sing	_	_	_	_
18	MHC	_	PROPN	_	Number=Sing	_	_	_	_
19	class	_	NOUN	_	Number=Sing	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	gene	_	VERB	_	Number=Sing	_	_	_	_
22	H-2Kb	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	indistinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	p50	_	NUM	_	Number=Sing	_	_	_	_
29	DNA	_	PROPN	_	Number=Sing	_	_	_	_
30	binding	_	VERB	_	Number=Sing	_	_	_	_
31	subunit	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappa	_	PROPN	_	Number=Sing	_	_	_	_
39	B	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	which	_	PRON	_	PronType=Rel	_	_	_	_
42	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	series	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	genes	_	NOUN	_	Number=Plur	_	_	_	_
47	involved	_	ADJ	_	Degree=Pos	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	immune	_	ADJ	_	Degree=Pos	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
52	responses	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	KBF1/p50	_	PROPN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	also	_	ADV	_	_	_	_	_	_
11	form	_	VERB	_	VerbForm=Inf	_	_	_	_
12	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	products	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	other	_	ADJ	_	Degree=Pos	_	_	_	_
18	members	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	same	_	ADJ	_	Degree=Pos	_	_	_	_
22	family	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	like	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	v-rel	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	proto	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	dimerization	_	NOUN	_	Number=Sing	_	_	_	_
3	domain	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	KBF1	_	PROPN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	p50	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	contained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	amino	_	PROPN	_	Number=Sing	_	_	_	_
12	acids	_	NOUN	_	Number=Plur	_	_	_	_
13	201	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	367	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	mutant	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	KBF1/p50	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	delta	_	PROPN	_	Number=Sing	_	_	_	_
7	SP	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	unable	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	DNA	_	PROPN	_	Number=Sing	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	able	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	form	_	VERB	_	VerbForm=Inf	_	_	_	_
19	homo	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	constructed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	reduces	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	abolishes	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	vitro	_	VERB	_	Number=Sing	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	DNA	_	PROPN	_	Number=Sing	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	wild	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	type	_	NOUN	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	same	_	ADJ	_	Degree=Pos	_	_	_	_
20	family	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	KBF1	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	p50	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	c	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	v-rel	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	mutant	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	functions	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	vivo	_	NOUN	_	Number=Sing	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	trans	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
13	negative	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulator	_	NOUN	_	Number=Sing	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	HIV	_	PROPN	_	Number=Sing	_	_	_	_
22	long	_	ADJ	_	Degree=Pos	_	_	_	_
23	terminal	_	NOUN	_	Number=Sing	_	_	_	_
24	repeat	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	which	_	PRON	_	PronType=Rel	_	_	_	_
27	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	two	_	NUM	_	NumType=Card	_	_	_	_
29	potential	_	ADJ	_	Degree=Pos	_	_	_	_
30	NF	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	binding	_	NOUN	_	Number=Sing	_	_	_	_
35	sites	_	NOUN	_	Number=Plur	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
39	ester	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	PMA	_	PROPN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
44	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	when	_	ADV	_	PronType=Int	_	_	_	_
46	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
47	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
48	co	_	NOUN	_	_	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
51	into	_	ADP	_	_	_	_	_	_
52	CD4	_	PROPN	_	Number=Sing	_	_	_	_
53	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	delta	_	PROPN	_	Number=Sing	_	_	_	_
6	SP	_	NOUN	_	Number=Sing	_	_	_	_
7	mutant	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Similarly	_	ADV	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	basal	_	NOUN	_	Number=Sing	_	_	_	_
4	as	_	ADV	_	_	_	_	_	_
5	well	_	ADV	_	Degree=Pos	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	IL1	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	MHC	_	PROPN	_	Number=Sing	_	_	_	_
16	class	_	NOUN	_	Number=Sing	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	H-2Kb	_	VERB	_	Number=Sing	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	can	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	mutant	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	two	_	NUM	_	NumType=Card	_	_	_	_
28	different	_	ADJ	_	Degree=Pos	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	lines	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	constitute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	formal	_	ADJ	_	Degree=Pos	_	_	_	_
7	demonstration	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	members	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	rel	_	PROPN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	family	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002588	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	MHC	_	PROPN	_	Number=Sing	_	_	_	_
3	class	_	NOUN	_	Number=Sing	_	_	_	_
4	II	_	NUM	_	NumType=Card	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	carboxyl	_	NOUN	_	Number=Sing	_	_	_	_
11	terminus	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	one	_	NUM	_	NumType=Card	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	defective	_	ADJ	_	Degree=Pos	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	type	_	NOUN	_	Number=Sing	_	_	_	_
22	II	_	NUM	_	NumType=Card	_	_	_	_
23	MHC	_	PROPN	_	Number=Sing	_	_	_	_
24	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	immune	_	ADJ	_	Degree=Pos	_	_	_	_
26	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Type	_	NOUN	_	Number=Sing	_	_	_	_
2	II	_	NUM	_	NumType=Card	_	_	_	_
3	major	_	ADJ	_	Degree=Pos	_	_	_	_
4	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
5	complex	_	NOUN	_	Number=Sing	_	_	_	_
6	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	immune	_	ADJ	_	Degree=Pos	_	_	_	_
8	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	II	_	NUM	_	NumType=Card	_	_	_	_
12	MHC	_	PROPN	_	Number=Sing	_	_	_	_
13	CID	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	bare	_	VERB	_	Degree=Pos	_	_	_	_
16	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
17	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	congenital	_	ADJ	_	Degree=Pos	_	_	_	_
22	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
23	disease	_	NOUN	_	Number=Sing	_	_	_	_
24	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	absent	_	ADJ	_	Degree=Pos	_	_	_	_
27	MHC	_	PROPN	_	Number=Sing	_	_	_	_
28	class	_	NOUN	_	Number=Sing	_	_	_	_
29	II	_	NUM	_	NumType=Card	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Four	_	NUM	_	NumType=Card	_	_	_	_
2	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
3	complementation	_	NOUN	_	Number=Sing	_	_	_	_
4	groups	_	NOUN	_	Number=Plur	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	defective	_	ADJ	_	Degree=Pos	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	group	_	NOUN	_	Number=Sing	_	_	_	_
8	II	_	NUM	_	NumType=Card	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	II	_	NUM	_	NumType=Card	_	_	_	_
11	MHC	_	PROPN	_	Number=Sing	_	_	_	_
12	CID	_	PROPN	_	Number=Sing	_	_	_	_
13	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
15	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	MHC	_	PROPN	_	Number=Sing	_	_	_	_
10	class	_	NOUN	_	Number=Sing	_	_	_	_
11	II	_	NUM	_	NumType=Card	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	activator	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	function	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	provided	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	N-	_	PROPN	_	Number=Sing	_	_	_	_
10	terminal	_	ADJ	_	Number=Sing	_	_	_	_
11	acidic	_	ADJ	_	Number=Sing	_	_	_	_
12	domain	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	amino	_	PROPN	_	Number=Sing	_	_	_	_
15	acids	_	NOUN	_	Number=Plur	_	_	_	_
16	26	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	137	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	experimentally	_	ADV	_	_	_	_	_	_
24	exchangeable	_	ADJ	_	Degree=Pos	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
28	viral	_	ADJ	_	Degree=Pos	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
32	domain	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	specificity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	three	_	NUM	_	NumType=Card	_	_	_	_
7	major	_	ADJ	_	Degree=Pos	_	_	_	_
8	MHC	_	PROPN	_	Number=Sing	_	_	_	_
9	class	_	NOUN	_	Number=Sing	_	_	_	_
10	II	_	NUM	_	Number=Sing	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	DR	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	DQ	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	DP	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	remaining	_	ADJ	_	VerbForm=Ger	_	_	_	_
24	C	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	terminal	_	NOUN	_	Number=Sing	_	_	_	_
27	residues	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	amino	_	PROPN	_	Number=Sing	_	_	_	_
30	acids	_	NOUN	_	Number=Plur	_	_	_	_
31	317	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	SYM	_	_	_	_	_	_
33	1130	_	NUM	_	NumType=Card	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
5	cis	_	NOUN	_	Number=Sing	_	_	_	_
6	elements	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	especially	_	ADV	_	_	_	_	_	_
9	S	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	X2	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	DR	_	PROPN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	group	_	NOUN	_	Number=Sing	_	_	_	_
21	II	_	NUM	_	NumType=Card	_	_	_	_
22	CID	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
3	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	normal	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
10	class	_	NOUN	_	Number=Sing	_	_	_	_
11	II	_	NUM	_	NumType=Card	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	initiation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	serves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	off	_	NOUN	_	Number=Sing	_	_	_	_
27	switch	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	while	_	SCONJ	_	_	_	_	_	_
30	availability	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
33	interactor	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	s	_	X	_	_	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	limits	_	NOUN	_	Number=Plur	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002594	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	PROPN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	independent	_	ADJ	_	Degree=Pos	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	domain	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
22	acid	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	purely	_	ADJ	_	_	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
12	such	_	ADJ	_	Degree=Pos	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	TNF	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	HIV	_	PROPN	_	Number=Sing	_	_	_	_
21	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	region	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	LTR	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
28	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	okadaic	_	PROPN	_	Number=Sing	_	_	_	_
31	acid	_	PROPN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	OKA	_	PROPN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	HIV	_	NOUN	_	Number=Sing	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	through	_	ADP	_	_	_	_	_	_
39	both	_	CCONJ	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	responding	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
44	to	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	factor	_	NOUN	_	Number=Sing	_	_	_	_
47	NF	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	kappa	_	PROPN	_	Number=Sing	_	_	_	_
50	B	_	PROPN	_	Number=Sing	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	promoter	_	ADJ	_	Number=Sing	_	_	_	_
55	domain	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
58	LTR	_	PROPN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	LTR	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	constructs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	lymphoblastoid	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	OKA	_	PROPN	_	Number=Sing	_	_	_	_
17	depended	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	both	_	DET	_	_	_	_	_	_
20	functional	_	ADJ	_	Degree=Pos	_	_	_	_
21	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	elements	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	ability	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	TATA	_	NOUN	_	Number=Sing	_	_	_	_
30	box	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	protein	_	NOUN	_	Number=Sing	_	_	_	_
35	TBP	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	both	_	DET	_	_	_	_	_	_
3	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	normal	_	ADJ	_	Degree=Pos	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	OKA	_	PROPN	_	Number=Sing	_	_	_	_
9	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	intense	_	ADJ	_	Degree=Pos	_	_	_	_
12	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	constitutively	_	ADV	_	_	_	_	_	_
16	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	property	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	OKA	_	PROPN	_	Number=Sing	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	shared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	TNF	_	PROPN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
33	ester	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	PHA	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	LTR	_	NOUN	_	Number=Sing	_	_	_	_
4	constructs	_	NOUN	_	Number=Plur	_	_	_	_
5	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	elements	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_

1	Tat	_	NOUN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	upon	_	ADP	_	_	_	_	_	_
6	OKA	_	PROPN	_	Number=Sing	_	_	_	_
7	but	_	CCONJ	_	_	_	_	_	_
8	not	_	ADV	_	_	_	_	_	_
9	TNF	_	ADJ	_	Number=Sing	_	_	_	_
10	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	SP1	_	PROPN	_	Number=Sing	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	OKA	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	selective	_	ADJ	_	Degree=Pos	_	_	_	_
13	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	serine	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	threonine	_	ADJ	_	Number=Sing	_	_	_	_
19	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
20	PP2A	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	facilitates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	formation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	complex	_	NOUN	_	Number=Sing	_	_	_	_
29	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
30	general	_	ADJ	_	Degree=Pos	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	factors	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	HIV	_	NOUN	_	Number=Sing	_	_	_	_
35	Tat	_	PROPN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
39	proteins	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	formation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	complex	_	NOUN	_	Number=Sing	_	_	_	_
6	would	_	AUX	_	VerbForm=Fin	_	_	_	_
7	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	independently	_	ADV	_	_	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	synergy	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	low	_	ADJ	_	Degree=Pos	_	_	_	_
22	basal	_	ADJ	_	Degree=Pos	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	HIV	_	PROPN	_	Number=Sing	_	_	_	_
27	LTR	_	PROPN	_	Number=Sing	_	_	_	_
28	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	normal	_	ADJ	_	Degree=Pos	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002595	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	association	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Nmi	_	PROPN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	signaling	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	coiled	_	ADJ	_	Degree=Pos	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	coil	_	NOUN	_	Number=Sing	_	_	_	_
6	region	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Stat5b	_	PROPN	_	Number=Sing	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	bait	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	yeast	_	ADJ	_	Number=Sing	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
18	screen	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
21	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	association	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	Nmi	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
31	function	_	NOUN	_	Number=Sing	_	_	_	_
32	previously	_	ADV	_	_	_	_	_	_
33	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	as	_	ADP	_	_	_	_	_	_
35	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	N	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	Myc	_	PROPN	_	Number=Sing	_	_	_	_
39	interactor	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Nmi	_	PROPN	_	Number=Sing	_	_	_	_
6	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	all	_	DET	_	_	_	_	_	_
9	STATs	_	NOUN	_	Number=Plur	_	_	_	_
10	except	_	ADP	_	_	_	_	_	_
11	Stat2	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	evaluated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	two	_	NUM	_	NumType=Card	_	_	_	_
4	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
5	systems	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	Nmi	_	PROPN	_	Number=Sing	_	_	_	_
17	augments	_	VERB	_	Number=Plur	_	_	_	_
18	STAT	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	mediated	_	VERB	_	Degree=Pos	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Nmi	_	PROPN	_	Number=Sing	_	_	_	_
4	lacks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	intrinsic	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	domain	_	NOUN	_	Number=Sing	_	_	_	_
10	;	_	PUNCT	_	_	_	_	_	_
11	instead	_	ADV	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	Nmi	_	PROPN	_	Number=Sing	_	_	_	_
14	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	association	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	CBP	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	p300	_	NOUN	_	Number=Sing	_	_	_	_
21	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	together	_	ADV	_	_	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	CBP	_	NOUN	_	Number=Sing	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	p300	_	NOUN	_	Number=Sing	_	_	_	_
34	can	_	AUX	_	VerbForm=Fin	_	_	_	_
35	augment	_	VERB	_	VerbForm=Inf	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
44	transcription	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	not	_	ADV	_	_	_	_	_	_
6	only	_	ADV	_	_	_	_	_	_
7	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	Nmi	_	PROPN	_	Number=Sing	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	potentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	STAT	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	also	_	ADV	_	_	_	_	_	_
19	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	can	_	AUX	_	VerbForm=Fin	_	_	_	_
23	augment	_	VERB	_	VerbForm=Inf	_	_	_	_
24	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	at	_	ADV	_	_	_	_	_	_
29	least	_	ADV	_	Degree=Sup	_	_	_	_
30	some	_	DET	_	_	_	_	_	_
31	members	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	group	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	sequence	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	specific	_	ADJ	_	Degree=Pos	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	factors	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003002600	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Vitamin	_	PROPN	_	Number=Sing	_	_	_	_
2	D	_	PROPN	_	Number=Sing	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	3'-	_	PUNCT	_	NumType=Card	_	_	_	_
5	untranslated	_	ADJ	_	Degree=Pos	_	_	_	_
6	region	_	NOUN	_	Number=Sing	_	_	_	_
7	polymorphisms	_	NOUN	_	Number=Plur	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	lack	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	effect	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
14	stability	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Allelic	_	PROPN	_	Number=Sing	_	_	_	_
2	variation	_	NOUN	_	Number=Sing	_	_	_	_
3	at	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	'-	_	PUNCT	_	_	_	_	_	_
7	end	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	vitamin	_	PROPN	_	Number=Sing	_	_	_	_
11	D	_	PROPN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	VDR	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	3	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	5	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	fold	_	NOUN	_	Number=Sing	_	_	_	_
27	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	risk	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	SCONJ	_	_	_	_	_	_
30	developing	_	VERB	_	VerbForm=Ger	_	_	_	_
31	prostate	_	ADJ	_	Number=Sing	_	_	_	_
32	cancer	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	differences	_	NOUN	_	Number=Plur	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	bone	_	NOUN	_	Number=Sing	_	_	_	_
38	mineralization	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
3	diversity	_	NOUN	_	Number=Sing	_	_	_	_
4	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	VDR	_	PROPN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	structurally	_	ADV	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	instead	_	ADV	_	_	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	marker	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	s	_	X	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	other	_	ADJ	_	Degree=Pos	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	nearby	_	ADV	_	Degree=Pos	_	_	_	_
25	polymorphisms	_	NOUN	_	Number=Plur	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	influence	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	message	_	NOUN	_	Number=Sing	_	_	_	_
29	stability	_	NOUN	_	Number=Sing	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	translation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	work	_	NOUN	_	Number=Sing	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	here	_	ADV	_	PronType=Dem	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	instigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
9	additional	_	ADJ	_	Degree=Pos	_	_	_	_
10	VDR	_	NOUN	_	Number=Sing	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	'-	_	PUNCT	_	_	_	_	_	_
13	UTR	_	PROPN	_	Number=Sing	_	_	_	_
14	polymorphisms	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	have	_	VERB	_	VerbForm=Inf	_	_	_	_
18	functional	_	ADJ	_	Degree=Pos	_	_	_	_
19	significance	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	then	_	ADV	_	PronType=Dem	_	_	_	_
23	test	_	VERB	_	VerbForm=Inf	_	_	_	_
24	whether	_	SCONJ	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
27	variants	_	NOUN	_	Number=Plur	_	_	_	_
28	alter	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	message	_	NOUN	_	Number=Sing	_	_	_	_
30	stability	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Initially	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	four	_	NUM	_	NumType=Card	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	frequently	_	ADV	_	_	_	_	_	_
7	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
8	sequence	_	NOUN	_	Number=Sing	_	_	_	_
9	variants	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	common	_	ADJ	_	Degree=Pos	_	_	_	_
17	haplotypes	_	NOUN	_	Number=Plur	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	previously	_	ADV	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	common	_	ADJ	_	Degree=Pos	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	variants	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	within	_	ADP	_	_	_	_	_	_
9	three	_	NUM	_	NumType=Card	_	_	_	_
10	message	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	destabilizing	_	ADJ	_	VerbForm=Ger	_	_	_	_
13	elements	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	mapped	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	within	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	3'-	_	ADJ	_	NumType=Card	_	_	_	_
20	UTR	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	vitamin	_	PROPN	_	Number=Sing	_	_	_	_
24	D	_	PROPN	_	Number=Sing	_	_	_	_
25	receptor	_	NOUN	_	Number=Sing	_	_	_	_
26	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	VDR	_	PROPN	_	Number=Sing	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	'-	_	PUNCT	_	_	_	_	_	_
8	UTR	_	PROPN	_	Number=Sing	_	_	_	_
9	haplotypes	_	NOUN	_	Number=Plur	_	_	_	_
10	conferred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	identical	_	ADJ	_	Degree=Pos	_	_	_	_
13	half	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	life	_	NOUN	_	Number=Sing	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	globin	_	ADJ	_	Degree=Pos	_	_	_	_
22	reporter	_	NOUN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	vitro	_	NOUN	_	Number=Sing	_	_	_	_
29	assay	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	common	_	ADJ	_	Degree=Pos	_	_	_	_
6	polymorphisms	_	NOUN	_	Number=Plur	_	_	_	_
7	within	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	VDR	_	PROPN	_	Number=Sing	_	_	_	_
10	3'-	_	NOUN	_	Number=Sing	_	_	_	_
11	UTR	_	NOUN	_	Number=Sing	_	_	_	_
12	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
15	message	_	NOUN	_	Number=Sing	_	_	_	_
16	stability	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030031	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Circadian	_	ADJ	_	Degree=Pos	_	_	_	_
2	rhythm	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
5	receptors	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
9	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	reactivity	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	1	_	X	_	_	_	_	_	_
2	)	_	PUNCT	_	_	_	_	_	_
3	There	_	PRON	_	_	_	_	_	_
4	exists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	CR	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	GR	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	PMN	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	peak	_	NOUN	_	Number=Sing	_	_	_	_
20	values	_	NOUN	_	Number=Plur	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	0400	_	NUM	_	NumType=Card	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	0800	_	NUM	_	NumType=Card	_	_	_	_
25	hr	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	trough	_	ADJ	_	Degree=Pos	_	_	_	_
29	values	_	NOUN	_	Number=Plur	_	_	_	_
30	between	_	ADP	_	_	_	_	_	_
31	2300	_	NUM	_	NumType=Card	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	0000	_	NUM	_	NumType=Card	_	_	_	_
34	hr	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	difference	_	NOUN	_	Number=Sing	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	significant	_	ADJ	_	Degree=Pos	_	_	_	_
7	statistically	_	ADV	_	_	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	2	_	X	_	_	_	_	_	_
2	)	_	PUNCT	_	_	_	_	_	_
3	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	FI	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
8	migration	_	NOUN	_	Number=Sing	_	_	_	_
9	rate	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	PMN	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	diurnal	_	ADJ	_	Degree=Pos	_	_	_	_
17	changes	_	NOUN	_	Number=Plur	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	synchronous	_	ADJ	_	Degree=Pos	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	GR	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	CR	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	GR	_	PROPN	_	Number=Sing	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	functional	_	ADJ	_	Degree=Pos	_	_	_	_
12	significance	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	3	_	X	_	_	_	_	_	_
2	)	_	PUNCT	_	_	_	_	_	_
3	In	_	ADP	_	_	_	_	_	_
4	Cushing	_	PROPN	_	Number=Sing	_	_	_	_
5	's	_	PART	_	_	_	_	_	_
6	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	CR	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	GR	_	PROPN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	normal	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	spite	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	fact	_	NOUN	_	Number=Sing	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	CR	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	plasma	_	NOUN	_	Number=Sing	_	_	_	_
24	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	disturbed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	independency	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	CR	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	GR	_	NOUN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	4	_	X	_	_	_	_	_	_
2	)	_	PUNCT	_	_	_	_	_	_
3	In	_	ADP	_	_	_	_	_	_
4	apoplexy	_	NOUN	_	Number=Sing	_	_	_	_
5	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	brain	_	NOUN	_	Number=Sing	_	_	_	_
8	ischemia	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	CR	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	GR	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	patients	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	basal	_	ADJ	_	Degree=Pos	_	_	_	_
20	lesions	_	NOUN	_	Number=Plur	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	preserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	when	_	ADV	_	PronType=Int	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	lesions	_	NOUN	_	Number=Plur	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	cerebral	_	ADJ	_	Degree=Pos	_	_	_	_
31	cortex	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	strongly	_	ADV	_	_	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	main	_	ADJ	_	Degree=Pos	_	_	_	_
8	"	_	PUNCT	_	_	_	_	_	_
9	circadian	_	ADJ	_	Degree=Pos	_	_	_	_
10	pacemaker	_	NOUN	_	Number=Sing	_	_	_	_
11	"	_	PUNCT	_	_	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	GR	_	PROPN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	basal	_	ADJ	_	Degree=Pos	_	_	_	_
19	brain	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	most	_	ADV	_	_	_	_	_	_
22	probably	_	ADV	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	suprachiasmatic	_	ADJ	_	Degree=Pos	_	_	_	_
26	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
27	as	_	SCONJ	_	_	_	_	_	_
28	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
30	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	rodents	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030032	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Progesterone	_	NOUN	_	Number=Sing	_	_	_	_
2	suppression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	pregnancy	_	NOUN	_	Number=Sing	_	_	_	_
5	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
11	effect	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	whether	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	suppressive	_	ADJ	_	Degree=Pos	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	pregnancy	_	NOUN	_	Number=Sing	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
18	receptors	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	competitive	_	ADJ	_	Degree=Pos	_	_	_	_
6	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
7	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	RU486	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	blocker	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	RU43044	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	tested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	release	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	blocking	_	NOUN	_	Number=Sing	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	pregnancy	_	NOUN	_	Number=Sing	_	_	_	_
34	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	RU	_	PROPN	_	Number=Sing	_	_	_	_
2	486	_	NUM	_	NumType=Card	_	_	_	_
3	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	at	_	ADP	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	equal	_	ADJ	_	Degree=Pos	_	_	_	_
7	concentration	_	NOUN	_	Number=Sing	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
10	significantly	_	ADV	_	_	_	_	_	_
11	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	blocking	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	while	_	SCONJ	_	_	_	_	_	_
20	RU	_	PROPN	_	Number=Sing	_	_	_	_
21	43044	_	NUM	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	without	_	ADP	_	_	_	_	_	_
24	effect	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	pregnancy	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
9	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
10	acts	_	NOUN	_	Number=Plur	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
14	receptors	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	involved	_	ADJ	_	Degree=Pos	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030033	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Infection	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	Theileria	_	PROPN	_	Number=Sing	_	_	_	_
4	annulata	_	NOUN	_	Number=Sing	_	_	_	_
5	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	matrix	_	ADJ	_	Number=Sing	_	_	_	_
9	metalloproteinase	_	NOUN	_	Number=Sing	_	_	_	_
10	9	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	bovine	_	NOUN	_	Number=Sing	_	_	_	_
19	leucocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Theileria	_	PROPN	_	Number=Sing	_	_	_	_
2	annulata	_	NOUN	_	Number=Sing	_	_	_	_
3	infects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	bovine	_	VERB	_	Degree=Pos	_	_	_	_
5	leucocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	results	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	reversible	_	ADJ	_	Degree=Pos	_	_	_	_
11	transformation	_	NOUN	_	Number=Sing	_	_	_	_
12	such	_	ADJ	_	Degree=Pos	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
15	become	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	immortalised	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	metastatic	_	ADJ	_	Degree=Pos	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	describes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	parasite	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	changes	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	host	_	ADJ	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	direct	_	ADJ	_	Degree=Pos	_	_	_	_
18	bearing	_	NOUN	_	Number=Sing	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	transformation	_	NOUN	_	Number=Sing	_	_	_	_
22	process	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	T.	_	PROPN	_	Number=Sing	_	_	_	_
2	annulata	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	leucocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	produce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	number	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	novel	_	NOUN	_	Number=Sing	_	_	_	_
11	metalloproteinase	_	NOUN	_	Number=Sing	_	_	_	_
12	activities	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	previously	_	ADV	_	_	_	_	_	_
6	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	B1	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	97	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kDa	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	secreted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	large	_	ADJ	_	Degree=Pos	_	_	_	_
20	amounts	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	purified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	free	_	ADJ	_	Degree=Pos	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	conditioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	medium	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	antiserum	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	isolate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
12	clone	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	predicted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	sequence	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	B1	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	81	_	NUM	_	NumType=Card	_	_	_	_
9	%	_	SYM	_	Number=Sing	_	_	_	_
10	identical	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	matrix	_	NOUN	_	Number=Sing	_	_	_	_
14	metalloproteinase	_	NOUN	_	Number=Sing	_	_	_	_
15	9	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	MMP9	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	bovine	_	NOUN	_	Number=Sing	_	_	_	_
26	homologue	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
29	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	RNAase	_	PROPN	_	Number=Sing	_	_	_	_
2	protection	_	NOUN	_	Number=Sing	_	_	_	_
3	assays	_	NOUN	_	Number=Plur	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	MMP9	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	unique	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	due	_	ADP	_	_	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	MMP9	_	NOUN	_	Number=Sing	_	_	_	_
20	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
21	levels	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	assayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	constitutively	_	ADV	_	_	_	_	_	_
18	present	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	amounts	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	Theileria	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	assayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	level	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
9	encoding	_	VERB	_	Number=Sing	_	_	_	_
10	c-Fos	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	common	_	ADJ	_	Degree=Pos	_	_	_	_
14	component	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	AP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	indeed	_	ADV	_	_	_	_	_	_
25	up	_	ADP	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	ADP	_	_	_	_	_	_
2	AP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	control	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	cycle	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	MMP9	_	PROPN	_	Number=Sing	_	_	_	_
17	can	_	AUX	_	VerbForm=Fin	_	_	_	_
18	confer	_	VERB	_	VerbForm=Inf	_	_	_	_
19	metastatic	_	ADJ	_	Degree=Pos	_	_	_	_
20	properties	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
23	results	_	NOUN	_	Number=Plur	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	considerable	_	ADJ	_	Degree=Pos	_	_	_	_
27	significance	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	respect	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
34	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	Theileria	_	PROPN	_	Number=Sing	_	_	_	_
37	infection	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030036	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tyloxapol	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibits	_	VERB	_	Number=Plur	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
9	release	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	scavenges	_	VERB	_	Number=Plur	_	_	_	_
12	HOCI	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	viscosity	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	cystic	_	ADJ	_	Degree=Pos	_	_	_	_
19	fibrosis	_	NOUN	_	Number=Sing	_	_	_	_
20	sputum	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Cystic	_	ADJ	_	Number=Sing	_	_	_	_
2	fibrosis	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	CF	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	patients	_	NOUN	_	Number=Plur	_	_	_	_
7	develop	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	progressive	_	ADJ	_	Degree=Pos	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
12	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	lung	_	NOUN	_	Number=Sing	_	_	_	_
14	disease	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	abundant	_	ADJ	_	Degree=Pos	_	_	_	_
18	production	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	thick	_	ADJ	_	Degree=Pos	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	tenacious	_	ADJ	_	Degree=Pos	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	protease	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	oxidant	_	ADJ	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	rich	_	ADJ	_	Degree=Pos	_	_	_	_
30	purulent	_	ADJ	_	Degree=Pos	_	_	_	_
31	airway	_	NOUN	_	Number=Sing	_	_	_	_
32	secretions	_	NOUN	_	Number=Plur	_	_	_	_
33	that	_	PRON	_	PronType=Rel	_	_	_	_
34	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	difficult	_	ADJ	_	Degree=Pos	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	clear	_	VERB	_	VerbForm=Inf	_	_	_	_
38	even	_	ADV	_	_	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	physiotherapy	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	search	_	NOUN	_	Number=Sing	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	potential	_	ADJ	_	Degree=Pos	_	_	_	_
7	treatment	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	tyloxapol	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	alkylaryl	_	ADJ	_	Degree=Pos	_	_	_	_
16	polyether	_	NOUN	_	Number=Sing	_	_	_	_
17	alcohol	_	NOUN	_	Number=Sing	_	_	_	_
18	polymer	_	NOUN	_	Number=Sing	_	_	_	_
19	detergent	_	NOUN	_	Number=Sing	_	_	_	_
20	previously	_	ADV	_	_	_	_	_	_
21	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	mucolytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	agent	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	adult	_	NOUN	_	Number=Sing	_	_	_	_
28	chronic	_	ADJ	_	Number=Sing	_	_	_	_
29	bronchitis	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Tyloxapol	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	NK	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	secretion	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
26	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	8	_	NUM	_	NumType=Card	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	8	_	NUM	_	NumType=Card	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	cultured	_	ADJ	_	Degree=Pos	_	_	_	_
36	human	_	ADJ	_	Degree=Pos	_	_	_	_
37	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	inhibits	_	NOUN	_	Degree=Pos	_	_	_	_
41	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	LPS	_	PROPN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	release	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	tumor	_	NOUN	_	Number=Sing	_	_	_	_
50	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
51	factor	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	alpha	_	PROPN	_	Number=Sing	_	_	_	_
54	(	_	PUNCT	_	_	_	_	_	_
55	TNF	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	alpha	_	PROPN	_	Number=Sing	_	_	_	_
58	)	_	PUNCT	_	_	_	_	_	_
59	,	_	PUNCT	_	_	_	_	_	_
60	IL	_	PROPN	_	Number=Sing	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	1	_	NUM	_	NumType=Card	_	_	_	_
63	beta	_	NOUN	_	Number=Sing	_	_	_	_
64	,	_	PUNCT	_	_	_	_	_	_
65	IL	_	PROPN	_	Number=Sing	_	_	_	_
66	-	_	PUNCT	_	_	_	_	_	_
67	6	_	NUM	_	NumType=Card	_	_	_	_
68	,	_	PUNCT	_	_	_	_	_	_
69	IL	_	PROPN	_	Number=Sing	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	8	_	NUM	_	NumType=Card	_	_	_	_
72	,	_	PUNCT	_	_	_	_	_	_
73	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
74	-	_	PUNCT	_	_	_	_	_	_
75	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
76	colony	_	NOUN	_	Number=Sing	_	_	_	_
77	-	_	PUNCT	_	_	_	_	_	_
78	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
79	factor	_	NOUN	_	Number=Sing	_	_	_	_
80	(	_	PUNCT	_	_	_	_	_	_
81	GM	_	PROPN	_	Number=Sing	_	_	_	_
82	-	_	PUNCT	_	_	_	_	_	_
83	CSF	_	PROPN	_	Number=Sing	_	_	_	_
84	)	_	PUNCT	_	_	_	_	_	_
85	,	_	PUNCT	_	_	_	_	_	_
86	and	_	CCONJ	_	_	_	_	_	_
87	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
88	eiconsanoids	_	NOUN	_	Number=Plur	_	_	_	_
89	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
90	A2	_	NOUN	_	Number=Sing	_	_	_	_
91	and	_	CCONJ	_	_	_	_	_	_
92	leukotriene	_	NOUN	_	Number=Sing	_	_	_	_
93	B4	_	NOUN	_	Number=Sing	_	_	_	_
94	(	_	PUNCT	_	_	_	_	_	_
95	LTB4	_	PROPN	_	Number=Sing	_	_	_	_
96	)	_	PUNCT	_	_	_	_	_	_
97	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	tyloxapol	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	potent	_	ADJ	_	Degree=Pos	_	_	_	_
10	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	hydroxyl	_	ADJ	_	Degree=Pos	_	_	_	_
13	radicals	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	OH	_	INTJ	_	_	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Tyloxapol	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	0.05	_	NUM	_	NumType=Card	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	0.1	_	NUM	_	NumType=Card	_	_	_	_
6	%	_	SYM	_	Number=Sing	_	_	_	_
7	wt	_	NUM	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	vol	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	effectively	_	ADV	_	_	_	_	_	_
12	scavenges	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
15	hypochlorous	_	ADJ	_	Number=Sing	_	_	_	_
16	acid	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	HOCl	_	NOUN	_	Number=Sing	_	_	_	_
19	;	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	7.5	_	NUM	_	NumType=Card	_	_	_	_
23	mM	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vitro	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	protects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	HOCl	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
34	lung	_	NOUN	_	Number=Sing	_	_	_	_
35	injury	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	rats	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Tyloxapol	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	viscosity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CF	_	PROPN	_	Number=Sing	_	_	_	_
8	sputum	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	463	_	NUM	_	NumType=Card	_	_	_	_
12	+/-	_	SYM	_	_	_	_	_	_
13	133	_	NUM	_	NumType=Card	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	128	_	NUM	_	NumType=Card	_	_	_	_
16	+/-	_	SYM	_	_	_	_	_	_
17	52	_	NUM	_	NumType=Card	_	_	_	_
18	centipoise	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	tyloxapol	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	potentially	_	ADV	_	_	_	_	_	_
7	useful	_	ADJ	_	Degree=Pos	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	new	_	ADJ	_	Degree=Pos	_	_	_	_
11	antiinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	therapy	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	CF	_	PROPN	_	Number=Sing	_	_	_	_
15	lung	_	NOUN	_	Number=Sing	_	_	_	_
16	disease	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	could	_	AUX	_	VerbForm=Fin	_	_	_	_
20	possibly	_	ADV	_	_	_	_	_	_
21	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
22	clearance	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	secretions	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	CF	_	PROPN	_	Number=Sing	_	_	_	_
28	airway	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030039	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	murine	_	NOUN	_	Number=Sing	_	_	_	_
3	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
13	early	_	ADJ	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
3	translocation	_	NOUN	_	Number=Sing	_	_	_	_
4	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
5	3q27	_	NUM	_	NumType=Card	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	often	_	ADV	_	_	_	_	_	_
8	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphomas	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	especially	_	ADV	_	_	_	_	_	_
17	diffuse	_	VERB	_	Degree=Pos	_	_	_	_
18	lymphomas	_	NOUN	_	Number=Plur	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	large	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	component	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
6	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
10	breakpoint	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	lymphomas	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	cloned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	murine	_	NOUN	_	Number=Sing	_	_	_	_
6	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	mBCL6	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	muscle	_	NOUN	_	Number=Sing	_	_	_	_
14	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
15	library	_	NOUN	_	Number=Sing	_	_	_	_
16	using	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	hBCL6	_	X	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	probe	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	predicted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	amino	_	NOUN	_	Number=Sing	_	_	_	_
4	acid	_	NOUN	_	Number=Sing	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	95	_	NUM	_	NumType=Card	_	_	_	_
8	%	_	SYM	_	Number=Sing	_	_	_	_
9	identical	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	hBCL6	_	PROPN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	six	_	NUM	_	NumType=Card	_	_	_	_
4	repeats	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Kruppel	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	like	_	ADJ	_	_	_	_	_	_
10	zinc	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	finger	_	NOUN	_	Number=Sing	_	_	_	_
13	motif	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	completely	_	ADV	_	_	_	_	_	_
17	identical	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	hBCL6	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	well	_	ADV	_	Degree=Pos	_	_	_	_
30	conserved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	between	_	ADP	_	_	_	_	_	_
32	humans	_	NOUN	_	Number=Plur	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	mice	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mBCL6	_	NOUN	_	Degree=Pos	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	ubiquitously	_	ADV	_	_	_	_	_	_
8	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	adult	_	NOUN	_	Number=Sing	_	_	_	_
11	mouse	_	NOUN	_	Number=Sing	_	_	_	_
12	tissues	_	NOUN	_	Number=Plur	_	_	_	_
13	including	_	VERB	_	VerbForm=Ger	_	_	_	_
14	lymphatic	_	ADJ	_	Degree=Pos	_	_	_	_
15	organs	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Sing	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
11	ester	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
14	+	_	SYM	_	_	_	_	_	_
15	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
16	within	_	ADP	_	_	_	_	_	_
17	30	_	NUM	_	NumType=Card	_	_	_	_
18	min	_	NOUN	_	Number=Plur	_	_	_	_
19	after	_	ADP	_	_	_	_	_	_
20	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	treatment	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
15	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
6	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
15	early	_	ADJ	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300310	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differences	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2R	_	NOUN	_	Number=Sing	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	JAK	_	PROPN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	STAT	_	PROPN	_	Number=Sing	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	between	_	ADP	_	_	_	_	_	_
15	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	I	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	independent	_	ADJ	_	Degree=Pos	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	lines	_	NOUN	_	Number=Plur	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	uncultured	_	ADJ	_	Degree=Pos	_	_	_	_
37	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	from	_	ADP	_	_	_	_	_	_
40	patients	_	NOUN	_	Number=Sing	_	_	_	_
41	with	_	ADP	_	_	_	_	_	_
42	adult	_	NOUN	_	Number=Sing	_	_	_	_
43	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
44	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
45	/	_	PUNCT	_	_	_	_	_	_
46	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	status	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2R	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	Jak	_	PROPN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	STAT	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	pathway	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
23	infected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
27	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	tyrosine	_	ADJ	_	Number=Sing	_	_	_	_
29	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	several	_	ADJ	_	Degree=Pos	_	_	_	_
39	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	+)	_	SYM	_	_	_	_	_	_
44	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
45	lines	_	NOUN	_	Number=Plur	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	uncultured	_	ADJ	_	Degree=Pos	_	_	_	_
49	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
50	T	_	NOUN	_	Number=Sing	_	_	_	_
51	cells	_	NOUN	_	Number=Plur	_	_	_	_
52	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
53	from	_	ADP	_	_	_	_	_	_
54	patients	_	NOUN	_	Number=Sing	_	_	_	_
55	with	_	ADP	_	_	_	_	_	_
56	adult	_	NOUN	_	Number=Sing	_	_	_	_
57	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
58	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
59	/	_	PUNCT	_	_	_	_	_	_
60	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
61	(	_	PUNCT	_	_	_	_	_	_
62	ATLL	_	NOUN	_	_	_	_	_	_
63	)	_	PUNCT	_	_	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	basal	_	ADJ	_	Degree=Pos	_	_	_	_
3	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	usually	_	ADV	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	all	_	DET	_	_	_	_	_	_
17	four	_	NUM	_	NumType=Card	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	independent	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	lines	_	NOUN	_	Number=Plur	_	_	_	_
25	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	none	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	three	_	NUM	_	NumType=Card	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	lines	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Similarly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	there	_	PRON	_	_	_	_	_	_
4	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	no	_	DET	_	_	_	_	_	_
6	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
7	basal	_	ADJ	_	Degree=Pos	_	_	_	_
8	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Jak3	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	ATLL	_	ADJ	_	Number=Sing	_	_	_	_
19	patients	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	0	_	NUM	_	NumType=Card	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	8	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	0/3	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	respectively	_	ADV	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
13	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
17	ATLL	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
25	lines	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	SHP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	negative	_	ADJ	_	Degree=Pos	_	_	_	_
13	regulator	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	signaling	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	lost	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	most	_	ADJ	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	independent	_	ADJ	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	lines	_	NOUN	_	Number=Plur	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	4	_	NUM	_	NumType=Card	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	not	_	PART	_	_	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
39	ATLL	_	PROPN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	0/3	_	NUM	_	NumType=Card	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	+)	_	SYM	_	_	_	_	_	_
9	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
10	lines	_	NOUN	_	Number=Plur	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	313	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	control	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	-)	_	PUNCT	_	_	_	_	_	_

1	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
2	lines	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
9	novel	_	NOUN	_	Number=Sing	_	_	_	_
10	analog	_	NOUN	_	Number=Sing	_	_	_	_
11	RAD	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	1	_	X	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	infection	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	per	_	ADP	_	_	_	_	_	_
12	se	_	PRON	_	Number=Sing	_	_	_	_
13	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	result	_	VERB	_	VerbForm=Inf	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
19	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	Jak3	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
28	proteins	_	NOUN	_	Number=Plur	_	_	_	_
29	;	_	PUNCT	_	_	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	2	_	X	_	_	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
34	transformation	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	at	_	ADV	_	_	_	_	_	_
37	least	_	ADV	_	Degree=Sup	_	_	_	_
38	some	_	DET	_	_	_	_	_	_
39	cases	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	ATLL	_	NOUN	_	Number=Sing	_	_	_	_
42	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
43	not	_	PART	_	_	_	_	_	_
44	require	_	VERB	_	VerbForm=Inf	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	constitutive	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	but	_	CCONJ	_	_	_	_	_	_
49	may	_	AUX	_	VerbForm=Fin	_	_	_	_
50	require	_	VERB	_	VerbForm=Inf	_	_	_	_
51	IL	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	2	_	NUM	_	NumType=Card	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	activation	_	NOUN	_	Number=Sing	_	_	_	_
58	of	_	ADP	_	_	_	_	_	_
59	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
60	IL	_	PROPN	_	Number=Sing	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	2R	_	PROPN	_	Number=Sing	_	_	_	_
63	Jak	_	NOUN	_	Number=Sing	_	_	_	_
64	/	_	PUNCT	_	_	_	_	_	_
65	STAT	_	PROPN	_	Number=Sing	_	_	_	_
66	pathway	_	NOUN	_	Number=Sing	_	_	_	_
67	;	_	PUNCT	_	_	_	_	_	_
68	and	_	CCONJ	_	_	_	_	_	_
69	(	_	PUNCT	_	_	_	_	_	_
70	3	_	X	_	_	_	_	_	_
71	)	_	PUNCT	_	_	_	_	_	_
72	there	_	PRON	_	_	_	_	_	_
73	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
74	major	_	ADJ	_	Degree=Pos	_	_	_	_
75	differences	_	NOUN	_	Number=Plur	_	_	_	_
76	in	_	ADP	_	_	_	_	_	_
77	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
78	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
79	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
80	(	_	PUNCT	_	_	_	_	_	_
81	s	_	X	_	_	_	_	_	_
82	)	_	PUNCT	_	_	_	_	_	_
83	which	_	PRON	_	PronType=Rel	_	_	_	_
84	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
85	to	_	PART	_	_	_	_	_	_
86	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
87	SHP	_	NOUN	_	Number=Sing	_	_	_	_
88	-	_	PUNCT	_	_	_	_	_	_
89	1	_	NUM	_	NumType=Card	_	_	_	_
90	and	_	CCONJ	_	_	_	_	_	_
91	target	_	NOUN	_	VerbForm=Inf	_	_	_	_
92	molecules	_	NOUN	_	Number=Plur	_	_	_	_
93	for	_	ADP	_	_	_	_	_	_
94	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
95	and	_	CCONJ	_	_	_	_	_	_
96	RAD	_	NOUN	_	Number=Sing	_	_	_	_
97	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300311	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	death	_	NOUN	_	Number=Sing	_	_	_	_
6	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	autoinduction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	negative	_	ADJ	_	Degree=Pos	_	_	_	_
6	autoregulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	GR	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	most	_	ADJ	_	Degree=Sup	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	tissues	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	GR	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	positively	_	ADV	_	_	_	_	_	_
25	autoregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
29	T	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	other	_	ADJ	_	Degree=Pos	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	death	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	positive	_	ADJ	_	Degree=Pos	_	_	_	_
5	autoregulation	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
9	component	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	death	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	wild	_	ADJ	_	Degree=Pos	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	GR	_	NOUN	_	Number=Sing	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	under	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	control	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	tetracycline	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	promoter	_	NOUN	_	Number=Sing	_	_	_	_
32	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
33	stably	_	ADV	_	_	_	_	_	_
34	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	into	_	ADP	_	_	_	_	_	_
36	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
41	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
42	functional	_	ADJ	_	Degree=Pos	_	_	_	_
43	receptor	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Transfectants	_	NOUN	_	Number=Plur	_	_	_	_
2	grown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	presence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	tetracycline	_	NOUN	_	Number=Sing	_	_	_	_
8	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	about	_	ADV	_	_	_	_	_	_
10	15,000	_	NUM	_	NumType=Card	_	_	_	_
11	receptors	_	NOUN	_	Number=Plur	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	value	_	NOUN	_	Number=Sing	_	_	_	_
17	approximately	_	ADV	_	_	_	_	_	_
18	equal	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	basal	_	ADJ	_	Degree=Pos	_	_	_	_
21	level	_	NOUN	_	Number=Sing	_	_	_	_
22	GR	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
28	6TG1.1	_	NUM	_	NumType=Card	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	before	_	ADP	_	_	_	_	_	_
31	steroid	_	ADJ	_	Degree=Pos	_	_	_	_
32	treatment	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Under	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	conditions	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
6	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	elicited	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
15	little	_	ADJ	_	Degree=Pos	_	_	_	_
16	internucleosomal	_	ADJ	_	Degree=Pos	_	_	_	_
17	DNA	_	NOUN	_	Number=Sing	_	_	_	_
18	fragmentation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	no	_	DET	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	cycle	_	NOUN	_	Number=Sing	_	_	_	_
25	perturbation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	absence	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	tetracycline	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	GR	_	PROPN	_	Number=Sing	_	_	_	_
8	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	2-3-	_	NUM	_	NumType=Card	_	_	_	_
14	fold	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	48,000	_	NUM	_	NumType=Card	_	_	_	_
20	receptors	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	level	_	NOUN	_	Number=Sing	_	_	_	_
24	nearly	_	ADV	_	_	_	_	_	_
25	equivalent	_	ADJ	_	Degree=Pos	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	present	_	ADJ	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	6TG1.1	_	NUM	_	NumType=Card	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	after	_	ADP	_	_	_	_	_	_
33	18	_	NUM	_	NumType=Card	_	_	_	_
34	h	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	autoinduction	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Under	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	conditions	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
6	markedly	_	ADV	_	_	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	growth	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	G1	_	NOUN	_	Number=Sing	_	_	_	_
13	arrest	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	significant	_	ADJ	_	Degree=Pos	_	_	_	_
18	internucleosomal	_	ADJ	_	Degree=Pos	_	_	_	_
19	DNA	_	NOUN	_	Number=Sing	_	_	_	_
20	fragmentation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	therefore	_	ADV	_	_	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	basal	_	ADJ	_	Degree=Pos	_	_	_	_
7	level	_	NOUN	_	Number=Sing	_	_	_	_
8	GR	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	inadequate	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	that	_	DET	_	_	_	_	_	_
26	positive	_	ADJ	_	Degree=Pos	_	_	_	_
27	autoregulation	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
31	component	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
34	process	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300312	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Modulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	normal	_	ADJ	_	Degree=Pos	_	_	_	_
4	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
9	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
10	hormone	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
13	acid	_	NOUN	_	Number=Sing	_	_	_	_
14	receptors	_	NOUN	_	Number=Plur	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	possible	_	ADJ	_	Degree=Pos	_	_	_	_
18	target	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	v-erbA	_	NOUN	_	Number=Sing	_	_	_	_
21	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
22	action	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	v-erbA	_	NOUN	_	Number=Sing	_	_	_	_
3	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	version	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
11	hormone	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	TR	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	inhibits	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	constitutively	_	ADV	_	_	_	_	_	_
27	represses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	certain	_	ADJ	_	Degree=Pos	_	_	_	_
31	erythrocyte	_	ADJ	_	Degree=Pos	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	normal	_	ADJ	_	Degree=Pos	_	_	_	_
37	function	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	proto	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
43	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	erythropoiesis	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
7	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
8	hormone	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	TR	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	closely	_	ADV	_	_	_	_	_	_
21	related	_	ADJ	_	Degree=Pos	_	_	_	_
22	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
23	acid	_	NOUN	_	Number=Sing	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	RAR	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	play	_	VERB	_	VerbForm=Inf	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	role	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	regulation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	normal	_	ADJ	_	Degree=Pos	_	_	_	_
39	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
40	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Retinoic	_	PROPN	_	Number=Sing	_	_	_	_
2	acid	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	RA	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	distinctly	_	ADV	_	_	_	_	_	_
7	modulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	program	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	normal	_	ADJ	_	Degree=Pos	_	_	_	_
14	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
15	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
18	reversibly	_	ADV	_	_	_	_	_	_
19	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	conditional	_	ADJ	_	Degree=Pos	_	_	_	_
23	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
24	kinase	_	NOUN	_	Number=Sing	_	_	_	_
25	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	added	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	pulsewise	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	immature	_	ADJ	_	VerbForm=Inf	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	accelerated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	while	_	SCONJ	_	_	_	_	_	_
12	more	_	ADJ	_	Degree=Cmp	_	_	_	_
13	mature	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	underwent	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	premature	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	death	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Thyroid	_	NOUN	_	Number=Sing	_	_	_	_
2	hormone	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	T3	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	alone	_	ADV	_	_	_	_	_	_
7	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	similar	_	ADJ	_	Degree=Pos	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	weaker	_	ADJ	_	Degree=Cmp	_	_	_	_
11	effects	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_

1	T3	_	PROPN	_	Number=Sing	_	_	_	_
2	strongly	_	ADV	_	_	_	_	_	_
3	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	action	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	RA	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
10	cooperative	_	ADJ	_	Degree=Pos	_	_	_	_
11	action	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	two	_	NUM	_	NumType=Card	_	_	_	_
15	receptors	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	SCONJ	_	_	_	_	_	_
17	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	RAR	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	negative	_	ADJ	_	Degree=Pos	_	_	_	_
12	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
13	conferred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	RA	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	otherwise	_	ADV	_	_	_	_	_	_
23	unresponsive	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	thus	_	ADV	_	_	_	_	_	_
27	showing	_	VERB	_	VerbForm=Ger	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	RAR	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	alpha	_	NOUN	_	Number=Sing	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	essential	_	ADJ	_	Degree=Pos	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	RA	_	PROPN	_	Number=Sing	_	_	_	_
38	effect	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Likewise	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
7	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	TR	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
14	rendered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
16	susceptible	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	modulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	T3	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	similar	_	ADJ	_	Degree=Pos	_	_	_	_
27	function	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	both	_	DET	_	_	_	_	_	_
30	receptors	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300319	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	internal	_	ADJ	_	Degree=Pos	_	_	_	_
3	methionine	_	NOUN	_	Number=Sing	_	_	_	_
4	codons	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
8	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
9	virus	_	NOUN	_	Number=Sing	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	II	_	NUM	_	NumType=Card	_	_	_	_
12	rex	_	NOUN	_	Degree=Pos	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	p24rex	_	NOUN	_	Number=Sing	_	_	_	_
19	production	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	virus	_	NOUN	_	Number=Sing	_	_	_	_
22	replication	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	transformation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	types	_	NOUN	_	Number=Plur	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	II	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	II	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	two	_	NUM	_	NumType=Card	_	_	_	_
21	nonstructural	_	ADJ	_	Degree=Pos	_	_	_	_
22	trans	_	NOUN	_	Number=Plur	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	tax	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	rex	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	3	_	NUM	_	NumType=Card	_	_	_	_
36	'	_	PUNCT	_	_	_	_	_	_
37	region	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	viral	_	ADJ	_	Degree=Pos	_	_	_	_
41	genome	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	tax	_	NOUN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	product	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	p40tax	_	VERB	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	II	_	NUM	_	NumType=Card	_	_	_	_
14	p37tax	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
19	activator	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	viral	_	ADJ	_	Degree=Pos	_	_	_	_
23	long	_	ADJ	_	Degree=Pos	_	_	_	_
24	terminal	_	NOUN	_	Number=Sing	_	_	_	_
25	repeat	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	rex	_	ADJ	_	Degree=Pos	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	products	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	p27rex	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	p21rex	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	p26rex	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	p24rex	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	II	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	respectively	_	ADV	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Rex	_	PROPN	_	Number=Sing	_	_	_	_
2	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	posttranscriptionally	_	ADV	_	_	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	facilitate	_	VERB	_	VerbForm=Inf	_	_	_	_
6	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	full	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	length	_	NOUN	_	Number=Sing	_	_	_	_
11	gag	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	pol	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	singly	_	ADV	_	_	_	_	_	_
16	spliced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	env	_	NOUN	_	Number=Sing	_	_	_	_
18	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	ATG	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	rex	_	NOUN	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	critical	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	Rex	_	NOUN	_	Number=Sing	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	function	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	importance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	internal	_	ADJ	_	Degree=Pos	_	_	_	_
6	ATGs	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	Rex	_	PROPN	_	Number=Sing	_	_	_	_
9	function	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vitro	_	ADJ	_	Number=Sing	_	_	_	_
5	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	rex	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	provided	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	indirect	_	ADJ	_	Degree=Pos	_	_	_	_
16	evidence	_	NOUN	_	Number=Sing	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	that	_	DET	_	_	_	_	_	_
20	p21rex	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	analogy	_	NOUN	_	Number=Sing	_	_	_	_
25	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	II	_	NUM	_	NumType=Card	_	_	_	_
28	p24rex	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	results	_	NOUN	_	Number=Plur	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	initiation	_	NOUN	_	Number=Sing	_	_	_	_
33	at	_	ADP	_	_	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	internal	_	ADJ	_	Degree=Pos	_	_	_	_
36	AUG	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	tax	_	NOUN	_	Number=Sing	_	_	_	_
40	/	_	PUNCT	_	_	_	_	_	_
41	rex	_	NOUN	_	Number=Sing	_	_	_	_
42	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	infectious	_	ADJ	_	Degree=Pos	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	clone	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	II	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	importance	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	internal	_	ADJ	_	Degree=Pos	_	_	_	_
19	ATGs	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	rex	_	ADJ	_	Degree=Pos	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	Rex	_	NOUN	_	Number=Sing	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	production	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	function	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	p24rex	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	II	_	PROPN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	initiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	internal	_	ADJ	_	Degree=Pos	_	_	_	_
16	AUG	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	internal	_	ADJ	_	Degree=Pos	_	_	_	_
21	methionine	_	NOUN	_	Number=Sing	_	_	_	_
22	codons	_	NOUN	_	Number=Plur	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	function	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	rex	_	ADJ	_	Degree=Pos	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	ultimately	_	ADV	_	_	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
39	properties	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	virus	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300320	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	[	_	PUNCT	_	_	_	_	_	_
2	Induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
9	:	_	PUNCT	_	_	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	physiology	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	pharmacology	_	NOUN	_	Number=Sing	_	_	_	_
14	]	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
4	molecules	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	extensively	_	ADV	_	_	_	_	_	_
9	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	clinics	_	NOUN	_	Number=Plur	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	anti-tumoral	_	ADJ	_	Degree=Pos	_	_	_	_
18	agents	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
2	can	_	AUX	_	VerbForm=Fin	_	_	_	_
3	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	normal	_	ADJ	_	Degree=Pos	_	_	_	_
7	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	play	_	VERB	_	VerbForm=Inf	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	key	_	ADJ	_	Degree=Pos	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	physiology	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
19	selection	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	clinics	_	NOUN	_	Number=Plur	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	molecules	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	potencies	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	SCONJ	_	_	_	_	_	_
12	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
16	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	mediating	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
4	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	after	_	SCONJ	_	_	_	_	_	_
7	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	belonging	_	VERB	_	VerbForm=Ger	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
18	:	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	GR	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Once	_	ADV	_	_	_	_	_	_
2	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	GR	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	his	_	PRON	_	Gender=Masc|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	effects	_	NOUN	_	Number=Plur	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	direct	_	ADJ	_	Degree=Pos	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	DNA	_	PROPN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	via	_	ADP	_	_	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	interactions	_	NOUN	_	Number=Plur	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factors	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Depending	_	VERB	_	VerbForm=Ger	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
15	fall	_	VERB	_	Number=Sing	_	_	_	_
16	roughly	_	ADV	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	two	_	NUM	_	NumType=Card	_	_	_	_
19	categories	_	NOUN	_	Number=Plur	_	_	_	_
20	:	_	PUNCT	_	_	_	_	_	_
21	induction	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	"	_	PUNCT	_	_	_	_	_	_
24	death	_	NOUN	_	Number=Sing	_	_	_	_
25	genes	_	NOUN	_	Number=Plur	_	_	_	_
26	"	_	PUNCT	_	_	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	GR	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
33	kappa	_	VERB	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	repression	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	survival	_	NOUN	_	Number=Sing	_	_	_	_
42	factors	_	NOUN	_	Number=Plur	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	AP	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	c	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	Myc	_	PROPN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	case	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
6	selection	_	NOUN	_	Number=Sing	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	more	_	ADV	_	_	_	_	_	_
11	subtle	_	ADJ	_	Degree=Pos	_	_	_	_
12	depending	_	VERB	_	VerbForm=Ger	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	mutual	_	ADJ	_	Degree=Pos	_	_	_	_
16	repression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	Nur77	_	PROPN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	GR	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300324	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	NFATp	_	PROPN	_	Number=Sing	_	_	_	_
7	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
9	DNA	_	NOUN	_	Number=Sing	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	cyclosporin	_	VERB	_	Number=Sing	_	_	_	_
14	A	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Cyclosporin	_	PROPN	_	Number=Sing	_	_	_	_
2	A	_	PROPN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	CsA	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
8	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	SCONJ	_	_	_	_	_	_
11	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	thus	_	ADV	_	_	_	_	_	_
26	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
27	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
28	induction	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	several	_	ADJ	_	Degree=Pos	_	_	_	_
31	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	largely	_	ADV	_	_	_	_	_	_
8	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
14	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	turn	_	NOUN	_	Number=Sing	_	_	_	_
19	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
20	translocation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
24	component	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CsA	_	PROPN	_	Number=Sing	_	_	_	_
6	treatment	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Raji	_	PROPN	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	lines	_	NOUN	_	Number=Plur	_	_	_	_
15	yields	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	form	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	DNA	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	binding	_	VERB	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	ability	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	form	_	VERB	_	VerbForm=Inf	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
36	complex	_	NOUN	_	Number=Sing	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	Fos	_	PROPN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	Jun	_	PROPN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Immunoblot	_	ADJ	_	Degree=Pos	_	_	_	_
2	analyses	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	metabolic	_	NOUN	_	Degree=Pos	_	_	_	_
5	labeling	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	[	_	PUNCT	_	_	_	_	_	_
8	32	_	NUM	_	NumType=Card	_	_	_	_
9	P	_	NOUN	_	Number=Sing	_	_	_	_
10	]	_	PUNCT	_	_	_	_	_	_
11	orthophosphate	_	NOUN	_	Number=Sing	_	_	_	_
12	show	_	VERB	_	Number=Sing	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	CsA	_	PROPN	_	Number=Sing	_	_	_	_
15	alters	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
17	migration	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	SDS	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	polyacrylamide	_	VERB	_	Number=Sing	_	_	_	_
22	gel	_	NOUN	_	Number=Sing	_	_	_	_
23	electrophoresis	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	SCONJ	_	_	_	_	_	_
25	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	level	_	NOUN	_	Number=Sing	_	_	_	_
29	without	_	SCONJ	_	_	_	_	_	_
30	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
31	subcellular	_	ADJ	_	Degree=Pos	_	_	_	_
32	distribution	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vitro	_	NOUN	_	Number=Sing	_	_	_	_
5	treatment	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	alkaline	_	ADJ	_	Degree=Pos	_	_	_	_
10	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
11	restores	_	VERB	_	Number=Plur	_	_	_	_
12	NFATp	_	PROPN	_	_	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	ability	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	reconstitute	_	VERB	_	VerbForm=Inf	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	Fos	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	Jun	_	PROPN	_	Number=Sing	_	_	_	_
28	proteins	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	point	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	new	_	ADJ	_	Degree=Pos	_	_	_	_
7	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	CsA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	which	_	DET	_	PronType=Rel	_	_	_	_
17	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	critical	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300327	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	mutation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	primary	_	ADJ	_	Degree=Pos	_	_	_	_
9	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
10	resistance	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	precise	_	ADJ	_	Number=Sing	_	_	_	_
3	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
4	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	cause	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	primary	_	ADJ	_	Degree=Pos	_	_	_	_
8	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
9	resistance	_	NOUN	_	Number=Sing	_	_	_	_
10	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	completely	_	ADV	_	_	_	_	_	_
14	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	subject	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	primary	_	ADJ	_	Degree=Pos	_	_	_	_
6	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
7	resistance	_	NOUN	_	Number=Sing	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
12	receptors	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	hGR	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	affinity	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	hypothesize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	mutation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	hGR	_	PROPN	_	Number=Sing	_	_	_	_
9	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	domain	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cause	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	cortisol	_	ADJ	_	Number=Sing	_	_	_	_
18	resistance	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Total	_	ADJ	_	Degree=Pos	_	_	_	_
2	RNA	_	PROPN	_	Number=Sing	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	index	_	NOUN	_	Number=Sing	_	_	_	_
7	subject	_	NOUN	_	Number=Sing	_	_	_	_
8	's	_	PART	_	_	_	_	_	_
9	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
15	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
16	strand	_	NOUN	_	Number=Sing	_	_	_	_
17	hGR	_	NOUN	_	Number=Sing	_	_	_	_
18	cDNAs	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	entire	_	ADJ	_	Degree=Pos	_	_	_	_
23	hGR	_	NOUN	_	Number=Sing	_	_	_	_
24	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	amplified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	segments	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	sequenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	nucleotide	_	NOUN	_	Number=Sing	_	_	_	_
3	2,317	_	NUM	_	NumType=Card	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	homozygous	_	ADJ	_	Number=Sing	_	_	_	_
8	A	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	G	_	PROPN	_	Number=Sing	_	_	_	_
11	point	_	NOUN	_	Number=Sing	_	_	_	_
12	mutation	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	predicts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	isoleucine	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	ATT	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	valine	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	GTT	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	substitution	_	NOUN	_	Number=Sing	_	_	_	_
26	at	_	ADP	_	_	_	_	_	_
27	amino	_	NOUN	_	Number=Sing	_	_	_	_
28	acid	_	NOUN	_	Number=Sing	_	_	_	_
29	729	_	NUM	_	NumType=Card	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	wild	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	hGR	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	hGR	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	Ile	_	PROPN	_	Number=Sing	_	_	_	_
11	729	_	NUM	_	NumType=Card	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	COS	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	assayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	[	_	PUNCT	_	_	_	_	_	_
23	3H	_	NUM	_	Number=Sing	_	_	_	_
24	]-	_	PUNCT	_	_	_	_	_	_
25	Dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
30	constants	_	NOUN	_	Number=Plur	_	_	_	_
31	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	0.799	_	NUM	_	NumType=Card	_	_	_	_
33	+/-	_	SYM	_	_	_	_	_	_
34	0.068	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	1.54	_	NUM	_	NumType=Card	_	_	_	_
37	+/-	_	SYM	_	_	_	_	_	_
38	0.06	_	NUM	_	NumType=Card	_	_	_	_
39	nM	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	mean	_	NOUN	_	Number=Sing	_	_	_	_
42	+/-	_	SYM	_	_	_	_	_	_
43	SEM	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	P	_	NOUN	_	Number=Sing	_	_	_	_
47	<	_	PUNCT	_	_	_	_	_	_
48	0.01	_	NUM	_	NumType=Card	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	respectively	_	ADV	_	_	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	wild	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	hGR	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	hGR	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	Ile	_	PROPN	_	Number=Sing	_	_	_	_
11	729	_	NUM	_	NumType=Card	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	CV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	cotransfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	mouse	_	NOUN	_	Number=Sing	_	_	_	_
25	mammary	_	ADJ	_	Number=Sing	_	_	_	_
26	tumor	_	NOUN	_	Number=Sing	_	_	_	_
27	virus	_	NOUN	_	Number=Sing	_	_	_	_
28	long	_	ADJ	_	Degree=Pos	_	_	_	_
29	terminal	_	NOUN	_	Number=Sing	_	_	_	_
30	repeat	_	NOUN	_	Number=Sing	_	_	_	_
31	fused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	chloramphenicol	_	NOUN	_	Number=Sing	_	_	_	_
35	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
36	transferase	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	CAT	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	hGR	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	Ile	_	PROPN	_	Number=Sing	_	_	_	_
46	729	_	NUM	_	NumType=Card	_	_	_	_
47	conferred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
48	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
49	fourfold	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	decrease	_	NOUN	_	Number=Sing	_	_	_	_
51	in	_	ADP	_	_	_	_	_	_
52	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
53	potency	_	NOUN	_	Number=Sing	_	_	_	_
54	on	_	ADP	_	_	_	_	_	_
55	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
56	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
57	of	_	ADP	_	_	_	_	_	_
58	CAT	_	NOUN	_	Number=Sing	_	_	_	_
59	activity	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	isoleucine	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	valine	_	ADJ	_	Number=Sing	_	_	_	_
5	substitution	_	NOUN	_	Number=Sing	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	amino	_	NOUN	_	Number=Sing	_	_	_	_
8	acid	_	NOUN	_	Number=Sing	_	_	_	_
9	729	_	NUM	_	NumType=Card	_	_	_	_
10	impairs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	function	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	hGR	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	likely	_	ADJ	_	Degree=Pos	_	_	_	_
20	cause	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	primary	_	ADJ	_	Degree=Pos	_	_	_	_
23	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
24	resistance	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
27	subject	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300340	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	role	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	PML	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	normal	_	ADJ	_	Degree=Pos	_	_	_	_
9	adult	_	NOUN	_	Number=Sing	_	_	_	_
10	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	functional	_	ADJ	_	Degree=Pos	_	_	_	_
13	interaction	_	NOUN	_	Number=Sing	_	_	_	_
14	between	_	ADP	_	_	_	_	_	_
15	PML	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	Rb	_	NOUN	_	Number=Sing	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	erythropoiesis	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	PML	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	early	_	ADJ	_	Degree=Pos	_	_	_	_
12	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
13	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	HPCs	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	unilineage	_	VERB	_	Degree=Pos	_	_	_	_
21	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	PML	_	PROPN	_	Number=Sing	_	_	_	_
2	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	while	_	SCONJ	_	_	_	_	_	_
7	barely	_	ADV	_	_	_	_	_	_
8	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	quiescent	_	ADJ	_	Degree=Pos	_	_	_	_
11	HPCs	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	consistently	_	ADV	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	growth	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	lineage	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Thereafter	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	PML	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	downmodulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	late	_	ADJ	_	Degree=Pos	_	_	_	_
8	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	maturation	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	whereas	_	SCONJ	_	_	_	_	_	_
12	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	sustainably	_	ADV	_	_	_	_	_	_
15	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
19	pathway	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	functional	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	PML	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	addition	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	antisense	_	ADJ	_	Number=Sing	_	_	_	_
13	oligomers	_	NOUN	_	Number=Plur	_	_	_	_
14	targeting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	PML	_	NOUN	_	Number=Sing	_	_	_	_
16	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	PML	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	early	_	ADJ	_	Degree=Pos	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	day	_	NOUN	_	Number=Sing	_	_	_	_
7	0	_	NUM	_	NumType=Card	_	_	_	_
8	HPCs	_	NOUN	_	Number=Plur	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	PML	_	PROPN	_	Number=Sing	_	_	_	_
14	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	number	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	both	_	DET	_	_	_	_	_	_
19	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	colonies	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	whereas	_	ADP	_	_	_	_	_	_
25	late	_	ADJ	_	Degree=Pos	_	_	_	_
26	treatment	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	day	_	NOUN	_	Number=Sing	_	_	_	_
29	5	_	NUM	_	NumType=Card	_	_	_	_
30	culture	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	but	_	CCONJ	_	_	_	_	_	_
36	not	_	ADV	_	_	_	_	_	_
37	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	clonogenesis	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	PML	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	early	_	ADJ	_	Degree=Pos	_	_	_	_
10	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
17	maturation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	pattern	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	PML	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	normal	_	ADJ	_	Degree=Pos	_	_	_	_
8	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
9	mimics	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
13	pRb	_	NOUN	_	Number=Sing	_	_	_	_
14	105	_	NUM	_	NumType=Card	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HPCs	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	alpha	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	PML	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Rb	_	NOUN	_	Number=Sing	_	_	_	_
13	oligomers	_	NOUN	_	Number=Plur	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	PML	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	Rb	_	PROPN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	completely	_	ADV	_	_	_	_	_	_
23	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
25	colony	_	NOUN	_	Number=Sing	_	_	_	_
26	development	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	PML	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	pRb	_	PROPN	_	Number=Sing	_	_	_	_
6	105	_	NUM	_	NumType=Card	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	co-immunoprecipitated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	lysates	_	NOUN	_	Number=Plur	_	_	_	_
12	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
15	precursors	_	NOUN	_	Number=Plur	_	_	_	_
16	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	functional	_	ADJ	_	Degree=Pos	_	_	_	_
20	interaction	_	NOUN	_	Number=Sing	_	_	_	_
21	may	_	AUX	_	VerbForm=Fin	_	_	_	_
22	have	_	VERB	_	VerbForm=Inf	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
25	basis	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	key	_	ADJ	_	Degree=Pos	_	_	_	_
6	functional	_	ADJ	_	Degree=Pos	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	PML	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	early	_	ADJ	_	Degree=Pos	_	_	_	_
12	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	late	_	ADJ	_	Degree=Pos	_	_	_	_
15	erythropoiesis	_	NOUN	_	Number=Sing	_	_	_	_
16	:	_	PUNCT	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	latter	_	ADJ	_	Degree=Pos	_	_	_	_
19	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	related	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	functional	_	ADJ	_	Degree=Pos	_	_	_	_
28	interaction	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	PML	_	NOUN	_	Number=Sing	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	pRb	_	PROPN	_	Number=Sing	_	_	_	_
33	105	_	NUM	_	NumType=Card	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300346	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
2	receptors	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	anorexia	_	ADJ	_	Number=Sing	_	_	_	_
5	nervosa	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	Cushing	_	PROPN	_	Number=Sing	_	_	_	_
8	's	_	PART	_	_	_	_	_	_
9	disease	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Patients	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	anorexia	_	ADJ	_	Degree=Pos	_	_	_	_
6	nervosa	_	NOUN	_	Number=Sing	_	_	_	_
7	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	display	_	VERB	_	VerbForm=Inf	_	_	_	_
10	cushingoid	_	ADJ	_	Degree=Pos	_	_	_	_
11	features	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	spite	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	elevated	_	ADJ	_	Degree=Pos	_	_	_	_
16	cortisol	_	ADJ	_	Number=Sing	_	_	_	_
17	plasma	_	NOUN	_	Number=Sing	_	_	_	_
18	levels	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Whether	_	SCONJ	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	cortisol	_	ADJ	_	Number=Sing	_	_	_	_
4	resistance	_	NOUN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	availability	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	metabolic	_	ADJ	_	Degree=Pos	_	_	_	_
12	substrates	_	NOUN	_	Number=Plur	_	_	_	_
13	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	develop	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	effect	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	glucocorticoids	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
24	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
27	established	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Twenty	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	patients	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	severe	_	ADJ	_	Degree=Pos	_	_	_	_
9	restrictive	_	ADJ	_	Degree=Pos	_	_	_	_
10	anorexia	_	ADJ	_	Number=Sing	_	_	_	_
11	nervosa	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	10	_	NUM	_	NumType=Card	_	_	_	_
14	patients	_	NOUN	_	Number=Plur	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	active	_	ADJ	_	Degree=Pos	_	_	_	_
17	Cushing	_	NOUN	_	Number=Sing	_	_	_	_
18	's	_	PART	_	_	_	_	_	_
19	disease	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	24	_	NUM	_	NumType=Card	_	_	_	_
23	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
24	volunteers	_	NOUN	_	Number=Plur	_	_	_	_
25	without	_	ADP	_	_	_	_	_	_
26	psychiatric	_	ADJ	_	Degree=Pos	_	_	_	_
27	disorders	_	NOUN	_	Number=Plur	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	mood	_	NOUN	_	Number=Sing	_	_	_	_
30	alterations	_	NOUN	_	Number=Plur	_	_	_	_
31	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	by	_	SCONJ	_	_	_	_	_	_
10	measuring	_	VERB	_	VerbForm=Ger	_	_	_	_
11	[	_	PUNCT	_	_	_	_	_	_
12	3H	_	NOUN	_	Number=Sing	_	_	_	_
13	]	_	PUNCT	_	_	_	_	_	_
14	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	effect	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	[	_	PUNCT	_	_	_	_	_	_
23	3H	_	NOUN	_	Number=Sing	_	_	_	_
24	]	_	PUNCT	_	_	_	_	_	_
25	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
26	incorporation	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	index	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	DNA	_	NOUN	_	Number=Sing	_	_	_	_
34	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	number	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
5	receptors	_	NOUN	_	Number=Plur	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	MNL	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	patients	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	anorexia	_	ADJ	_	Degree=Pos	_	_	_	_
18	nervosa	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	patients	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	active	_	ADJ	_	Degree=Pos	_	_	_	_
23	Cushing	_	NOUN	_	Number=Sing	_	_	_	_
24	's	_	PART	_	_	_	_	_	_
25	disease	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	normal	_	ADJ	_	Degree=Pos	_	_	_	_
29	subjects	_	NOUN	_	Number=Plur	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	binding	_	NOUN	_	Number=Sing	_	_	_	_
32	capacity	_	NOUN	_	Number=Sing	_	_	_	_
33	3.3	_	NUM	_	NumType=Card	_	_	_	_
34	+/-	_	SYM	_	_	_	_	_	_
35	0.23	_	NUM	_	NumType=Card	_	_	_	_
36	vs.	_	ADP	_	_	_	_	_	_
37	3.7	_	NUM	_	NumType=Card	_	_	_	_
38	+/-	_	SYM	_	_	_	_	_	_
39	0.30	_	NUM	_	NumType=Card	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	3.5	_	NUM	_	NumType=Card	_	_	_	_
42	+/-	_	SYM	_	_	_	_	_	_
43	0.20	_	NUM	_	NumType=Card	_	_	_	_
44	fmol	_	NOUN	_	Number=Sing	_	_	_	_
45	/	_	PUNCT	_	_	_	_	_	_
46	10	_	NUM	_	NumType=Card	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	6	_	NUM	_	NumType=Card	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	cells	_	NOUN	_	Number=Plur	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Conversely	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	affinity	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	significantly	_	ADV	_	_	_	_	_	_
8	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	anorexia	_	ADJ	_	Degree=Pos	_	_	_	_
11	nervosa	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADV	_	_	_	_	_	_
13	well	_	ADV	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	Cushing	_	PROPN	_	Number=Sing	_	_	_	_
17	's	_	PART	_	_	_	_	_	_
18	patients	_	NOUN	_	Number=Plur	_	_	_	_
19	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	control	_	VERB	_	VerbForm=Inf	_	_	_	_
22	subjects	_	NOUN	_	Number=Plur	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
25	constant	_	ADJ	_	Degree=Pos	_	_	_	_
26	4.0	_	NUM	_	NumType=Card	_	_	_	_
27	+/-	_	SYM	_	_	_	_	_	_
28	0.31	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	4.1	_	NUM	_	NumType=Card	_	_	_	_
31	+/-	_	SYM	_	_	_	_	_	_
32	0.34	_	NUM	_	NumType=Card	_	_	_	_
33	vs.	_	ADP	_	_	_	_	_	_
34	2.9	_	NUM	_	NumType=Card	_	_	_	_
35	+/-	_	SYM	_	_	_	_	_	_
36	0.29	_	NUM	_	NumType=Card	_	_	_	_
37	nmol	_	NOUN	_	Number=Sing	_	_	_	_
38	/	_	PUNCT	_	_	_	_	_	_
39	L	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	p	_	NOUN	_	Number=Sing	_	_	_	_
42	<	_	PUNCT	_	_	_	_	_	_
43	.001	_	NUM	_	NumType=Card	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	inversely	_	ADV	_	_	_	_	_	_
47	correlated	_	VERB	_	Degree=Pos	_	_	_	_
48	with	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	levels	_	NOUN	_	Number=Plur	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	urinary	_	ADJ	_	Degree=Pos	_	_	_	_
53	free	_	ADJ	_	Degree=Pos	_	_	_	_
54	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	both	_	DET	_	_	_	_	_	_
57	groups	_	NOUN	_	Number=Plur	_	_	_	_
58	of	_	ADP	_	_	_	_	_	_
59	patients	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Basal	_	PROPN	_	Number=Sing	_	_	_	_
2	[	_	PUNCT	_	_	_	_	_	_
3	3H	_	X	_	Number=Sing	_	_	_	_
4	]	_	PUNCT	_	_	_	_	_	_
5	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
6	incorporation	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	MNL	_	PROPN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	significantly	_	ADV	_	_	_	_	_	_
11	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	anorexia	_	ADJ	_	Degree=Pos	_	_	_	_
14	nervosa	_	NOUN	_	Number=Sing	_	_	_	_
15	as	_	ADV	_	_	_	_	_	_
16	well	_	ADV	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	Cushing	_	PROPN	_	Number=Sing	_	_	_	_
20	's	_	PART	_	_	_	_	_	_
21	patients	_	NOUN	_	Number=Plur	_	_	_	_
22	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	control	_	VERB	_	VerbForm=Inf	_	_	_	_
25	subjects	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	p	_	NOUN	_	Number=Sing	_	_	_	_
28	<	_	PUNCT	_	_	_	_	_	_
29	.001	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
33	diminished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	extent	_	NOUN	_	Number=Sing	_	_	_	_
39	similar	_	ADJ	_	Degree=Pos	_	_	_	_
40	to	_	PART	_	_	_	_	_	_
41	control	_	VERB	_	VerbForm=Inf	_	_	_	_
42	subjects	_	NOUN	_	Number=Plur	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	patients	_	NOUN	_	Number=Sing	_	_	_	_
45	with	_	ADP	_	_	_	_	_	_
46	anorexia	_	ADJ	_	Number=Sing	_	_	_	_
47	nervosa	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	but	_	CCONJ	_	_	_	_	_	_
50	significantly	_	ADV	_	_	_	_	_	_
51	(	_	PUNCT	_	_	_	_	_	_
52	p	_	NOUN	_	Number=Sing	_	_	_	_
53	<	_	PUNCT	_	_	_	_	_	_
54	.001	_	NUM	_	NumType=Card	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	less	_	ADJ	_	Degree=Cmp	_	_	_	_
57	in	_	ADP	_	_	_	_	_	_
58	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
59	with	_	ADP	_	_	_	_	_	_
60	Cushing	_	PROPN	_	Number=Sing	_	_	_	_
61	's	_	PART	_	_	_	_	_	_
62	disease	_	NOUN	_	Number=Sing	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	patients	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	anorexia	_	ADJ	_	Number=Sing	_	_	_	_
5	nervosa	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	incorporation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	[	_	PUNCT	_	_	_	_	_	_
11	3H	_	NOUN	_	Number=Sing	_	_	_	_
12	]	_	PUNCT	_	_	_	_	_	_
13	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
14	into	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	MNL	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	inversely	_	ADV	_	_	_	_	_	_
19	correlated	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	urinary	_	ADJ	_	Degree=Pos	_	_	_	_
22	free	_	ADJ	_	Degree=Pos	_	_	_	_
23	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
24	levels	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	lack	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	cushingoid	_	ADJ	_	Degree=Pos	_	_	_	_
11	features	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	patients	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	anorexia	_	ADJ	_	Degree=Pos	_	_	_	_
16	nervosa	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	ascribable	_	ADJ	_	Degree=Pos	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	more	_	ADV	_	_	_	_	_	_
29	likely	_	ADJ	_	Degree=Pos	_	_	_	_
30	due	_	ADP	_	_	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	paucity	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	metabolic	_	ADJ	_	Degree=Pos	_	_	_	_
36	substrates	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300349	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Genes	_	NOUN	_	Number=Plur	_	_	_	_
2	that	_	PRON	_	PronType=Rel	_	_	_	_
3	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	immunomodulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	central	_	ADJ	_	Degree=Pos	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	allergic	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	atopic	_	ADJ	_	Degree=Pos	_	_	_	_
20	immune	_	NOUN	_	Number=Sing	_	_	_	_
21	responses	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Significant	_	ADJ	_	Degree=Pos	_	_	_	_
2	progress	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	made	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	SCONJ	_	_	_	_	_	_
7	gaining	_	VERB	_	VerbForm=Ger	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	detailed	_	ADJ	_	Degree=Pos	_	_	_	_
10	understanding	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	4	_	NUM	_	NumType=Card	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	recent	_	ADJ	_	Degree=Pos	_	_	_	_
3	identification	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	characterization	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	several	_	ADJ	_	Degree=Pos	_	_	_	_
8	key	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	helped	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	elucidate	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
17	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	helper	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300354	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	signal	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	ERK	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	ERK	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	independent	_	ADJ	_	Degree=Pos	_	_	_	_
16	pathways	_	NOUN	_	Number=Plur	_	_	_	_
17	target	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	serine	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	727	_	NUM	_	NumType=Card	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
26	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
29	factors	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	signal	_	NOUN	_	Number=Sing	_	_	_	_
4	transducer	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	activator	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	latent	_	ADJ	_	Degree=Pos	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
21	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	Tyr	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	705	_	NUM	_	NumType=Card	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	growth	_	NOUN	_	Number=Sing	_	_	_	_
34	factors	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	one	_	NUM	_	NumType=Card	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	more	_	ADJ	_	Degree=Cmp	_	_	_	_
8	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
9	serine	_	NOUN	_	Number=Sing	_	_	_	_
10	kinases	_	NOUN	_	Number=Plur	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	phosphorylate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	antibody	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	Ser	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	727	_	NUM	_	NumType=Card	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
23	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
26	factors	_	NOUN	_	Number=Plur	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	N	_	X	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	formyl	_	ADJ	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	methionyl	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	leucyl	_	ADJ	_	Degree=Pos	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	phenylalanine	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	complement	_	NOUN	_	Number=Sing	_	_	_	_
39	C5a	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
43	[	_	PUNCT	_	_	_	_	_	_
44	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
45	/	_	PUNCT	_	_	_	_	_	_
46	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
47	colony	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
50	factor	_	NOUN	_	Number=Sing	_	_	_	_
51	(	_	PUNCT	_	_	_	_	_	_
52	GM	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	CSF	_	PROPN	_	Number=Sing	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
58	colony	_	NOUN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
61	factor	_	NOUN	_	Number=Sing	_	_	_	_
62	(	_	PUNCT	_	_	_	_	_	_
63	G	_	PROPN	_	Number=Sing	_	_	_	_
64	-	_	PUNCT	_	_	_	_	_	_
65	CSF	_	NOUN	_	Number=Sing	_	_	_	_
66	)	_	PUNCT	_	_	_	_	_	_
67	]	_	PUNCT	_	_	_	_	_	_
68	,	_	PUNCT	_	_	_	_	_	_
69	or	_	CCONJ	_	_	_	_	_	_
70	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
71	protein	_	NOUN	_	Number=Sing	_	_	_	_
72	kinase	_	NOUN	_	Number=Sing	_	_	_	_
73	C	_	NOUN	_	Number=Sing	_	_	_	_
74	activator	_	NOUN	_	Number=Sing	_	_	_	_
75	(	_	PUNCT	_	_	_	_	_	_
76	PMA	_	PROPN	_	Number=Sing	_	_	_	_
77	)	_	PUNCT	_	_	_	_	_	_
78	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	2-Amino-3'-	_	NUM	_	_	_	_	_	_
3	methoxyphenyl	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	oxanaphthalen-4-one	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	PD	_	NOUN	_	Number=Sing	_	_	_	_
8	98059	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	signal	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	kinase	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	ERK	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	serine	_	NOUN	_	Number=Sing	_	_	_	_
28	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
31	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
34	factors	_	NOUN	_	Number=Plur	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	PMA	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	drug	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	less	_	ADV	_	Degree=Cmp	_	_	_	_
5	effective	_	ADJ	_	Degree=Pos	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
10	virtually	_	ADV	_	_	_	_	_	_
11	abolished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	GM	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	CSF	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	5	_	NUM	_	NumType=Card	_	_	_	_
21	min	_	NOUN	_	Number=Plur	_	_	_	_
22	after	_	ADP	_	_	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	only	_	ADV	_	_	_	_	_	_
26	partly	_	ADV	_	_	_	_	_	_
27	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
29	at	_	ADP	_	_	_	_	_	_
30	15	_	NUM	_	NumType=Card	_	_	_	_
31	-	_	SYM	_	_	_	_	_	_
32	30	_	NUM	_	NumType=Card	_	_	_	_
33	min	_	NOUN	_	Number=Plur	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	not	_	PART	_	_	_	_	_	_
37	appreciably	_	ADV	_	_	_	_	_	_
38	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
39	responses	_	NOUN	_	Number=Plur	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	G	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	CSF	_	NOUN	_	Number=Sing	_	_	_	_
44	regardless	_	ADV	_	_	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	incubation	_	NOUN	_	Number=Sing	_	_	_	_
47	time	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	1-(5	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Isoquinolinylsulphonyl	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	-2-methylpiperazine	_	PUNCT	_	_	_	_	_	_
6	dihydrochloride	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	H7	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	putative	_	ADJ	_	Degree=Pos	_	_	_	_
16	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
17	serine	_	NOUN	_	Number=Sing	_	_	_	_
18	kinase	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	4-(4	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	fluorophenyl	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2-(4	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	methylsulphinylphenyl)-5-(4-pyridyl	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_

1	1H-imidazole	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	SB	_	PROPN	_	Number=Sing	_	_	_	_
4	203580	_	NUM	_	NumType=Card	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	p38	_	NOUN	_	Number=Sing	_	_	_	_
11	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	MAP	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	kinase	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	dampen	_	VERB	_	VerbForm=Inf	_	_	_	_
23	any	_	DET	_	_	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	serine	_	NOUN	_	Number=Sing	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	responses	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
5	use	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	ERK	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	ERK	_	ADJ	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	independent	_	ADJ	_	Degree=Pos	_	_	_	_
14	pathways	_	NOUN	_	Number=Plur	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	phosphorylate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	Ser-727	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	former	_	ADJ	_	Degree=Pos	_	_	_	_
3	pathway	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	recruited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	all	_	DET	_	_	_	_	_	_
8	ERK	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	whereas	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	latter	_	ADJ	_	Degree=Pos	_	_	_	_
16	pathway	_	NOUN	_	Number=Sing	_	_	_	_
17	uses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	undefined	_	ADJ	_	Degree=Pos	_	_	_	_
20	serine	_	NOUN	_	Number=Sing	_	_	_	_
21	kinase	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	recruited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	selectively	_	ADV	_	_	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300356	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Effects	_	PROPN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	10	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	4	_	NUM	_	NumType=Card	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	LPS	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	AP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	IL6	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	PROPN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	which	_	PRON	_	PronType=Rel	_	_	_	_
31	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	involved	_	ADJ	_	Degree=Pos	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	6	_	NUM	_	NumType=Card	_	_	_	_
37	regulation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-10	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	10	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	like	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
17	cytokine	_	ADJ	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	10	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	inhibit	_	VERB	_	Number=Sing	_	_	_	_
13	LPS	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	6	_	NUM	_	NumType=Card	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	SCONJ	_	_	_	_	_	_
24	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	rate	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	6	_	NUM	_	NumType=Card	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	strong	_	ADJ	_	Degree=Pos	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	rate	_	NOUN	_	Number=Sing	_	_	_	_
11	prompted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	us	_	PRON	_	Case=Acc|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	study	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	effect	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	10	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factors	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	questioned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	not	_	ADV	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	10	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	affected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	involved	_	ADJ	_	Degree=Pos	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	control	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	6	_	NUM	_	NumType=Card	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	rate	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	namely	_	ADV	_	Number=Sing	_	_	_	_
37	activator	_	NOUN	_	Number=Sing	_	_	_	_
38	protein	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	AP	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
48	factor	_	NOUN	_	Number=Sing	_	_	_	_
49	IL	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	6	_	NUM	_	NumType=Card	_	_	_	_
52	(	_	PUNCT	_	_	_	_	_	_
53	NF	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	IL6	_	PROPN	_	Number=Sing	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	and	_	CCONJ	_	_	_	_	_	_
59	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
60	factor	_	NOUN	_	Number=Sing	_	_	_	_
61	kappa	_	NOUN	_	Number=Sing	_	_	_	_
62	B	_	PROPN	_	Number=Sing	_	_	_	_
63	(	_	PUNCT	_	_	_	_	_	_
64	NF	_	PROPN	_	Number=Sing	_	_	_	_
65	-	_	PUNCT	_	_	_	_	_	_
66	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
67	)	_	PUNCT	_	_	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	EMSAs	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	10	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	4	_	NUM	_	NumType=Card	_	_	_	_
19	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	LPS	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	AP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	slightly	_	ADV	_	_	_	_	_	_
10	more	_	ADV	_	_	_	_	_	_
11	pronounced	_	ADJ	_	Degree=Pos	_	_	_	_
12	than	_	ADP	_	_	_	_	_	_
13	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	10	_	NUM	_	NumType=Card	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Downregulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	LPS	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	AP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	thus	_	ADV	_	_	_	_	_	_
14	possibly	_	ADV	_	_	_	_	_	_
15	explained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
23	level	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	two	_	NUM	_	NumType=Card	_	_	_	_
27	major	_	ADJ	_	Degree=Pos	_	_	_	_
28	components	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	AP	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	complex	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	namely	_	ADJ	_	Number=Sing	_	_	_	_
37	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	c	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	jun	_	NOUN	_	Number=Sing	_	_	_	_
42	as	_	SCONJ	_	_	_	_	_	_
43	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	by	_	ADP	_	_	_	_	_	_
45	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
46	experiments	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	IL6	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	strongly	_	ADV	_	_	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	whereas	_	SCONJ	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	10	_	NUM	_	NumType=Card	_	_	_	_
19	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	no	_	DET	_	_	_	_	_	_
21	effect	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	IL6	_	PROPN	_	Number=Sing	_	_	_	_
4	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	10	_	NUM	_	NumType=Card	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	4	_	NUM	_	NumType=Card	_	_	_	_
23	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	binding	_	VERB	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	SCONJ	_	_	_	_	_	_
27	preexisting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	IL6	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Neither	_	CCONJ	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	10	_	NUM	_	NumType=Card	_	_	_	_
5	nor	_	CCONJ	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	LPS	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	agreement	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	finding	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
8	experiments	_	NOUN	_	Number=Plur	_	_	_	_
9	where	_	ADV	_	PronType=Rel	_	_	_	_
10	p65	_	NUM	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	p105	_	NUM	_	Number=Sing	_	_	_	_
13	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
23	components	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	not	_	PART	_	_	_	_	_	_
34	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	10	_	NUM	_	NumType=Card	_	_	_	_
39	or	_	CCONJ	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	4	_	NUM	_	NumType=Card	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	neither	_	CCONJ	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	10	_	NUM	_	NumType=Card	_	_	_	_
7	nor	_	CCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	any	_	DET	_	_	_	_	_	_
13	effect	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	I	_	PRON	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	as	_	SCONJ	_	_	_	_	_	_
22	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
25	experiments	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	10	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	4	_	NUM	_	NumType=Card	_	_	_	_
10	similarly	_	ADV	_	_	_	_	_	_
11	affect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	6	_	NUM	_	NumType=Card	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	reduction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	IL6	_	PROPN	_	Number=Sing	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	whereas	_	SCONJ	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	10	_	NUM	_	NumType=Card	_	_	_	_
27	only	_	ADV	_	_	_	_	_	_
28	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	AP	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	activity	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300363	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Thyroid	_	NOUN	_	Number=Sing	_	_	_	_
2	hormone	_	NOUN	_	Number=Sing	_	_	_	_
3	receptors	_	NOUN	_	Number=Plur	_	_	_	_
4	form	_	VERB	_	Number=Sing	_	_	_	_
5	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	independent	_	ADJ	_	Degree=Pos	_	_	_	_
12	complexes	_	NOUN	_	Number=Plur	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
16	hormone	_	NOUN	_	Number=Sing	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	element	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
11	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
12	hormone	_	NOUN	_	Number=Sing	_	_	_	_
13	receptors	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TRs	_	NOUN	_	Number=Plur	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	palindromic	_	ADJ	_	Degree=Pos	_	_	_	_
20	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
21	hormone	_	NOUN	_	Number=Sing	_	_	_	_
22	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
23	element	_	NOUN	_	Number=Sing	_	_	_	_
24	AGGTCATGACCT	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	TREp	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	using	_	VERB	_	VerbForm=Ger	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	gel	_	NOUN	_	Number=Sing	_	_	_	_
31	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
32	mobility	_	NOUN	_	Number=Sing	_	_	_	_
33	shift	_	NOUN	_	Number=Sing	_	_	_	_
34	assay	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Four	_	NUM	_	NumType=Card	_	_	_	_
2	specific	_	ADJ	_	Degree=Pos	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	DNA	_	NOUN	_	Number=Sing	_	_	_	_
6	complexes	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	after	_	ADP	_	_	_	_	_	_
10	incubation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	extracts	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	NE	_	X	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	T3	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
21	pituitary	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	GH3	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	TREp	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
31	DNA	_	NOUN	_	Number=Sing	_	_	_	_
32	fragment	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	TREp	_	PROPN	_	Number=Sing	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	reticulocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	lysate	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	TRs	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	TR	_	PROPN	_	Number=Sing	_	_	_	_
2	alpha	_	PROPN	_	Number=Sing	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	TR	_	PROPN	_	Number=Sing	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	each	_	DET	_	_	_	_	_	_
9	formed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	single	_	ADJ	_	Degree=Pos	_	_	_	_
12	major	_	ADJ	_	Degree=Pos	_	_	_	_
13	TR	_	NOUN	_	Number=Sing	_	_	_	_
14	:	_	PUNCT	_	_	_	_	_	_
15	TREp	_	NOUN	_	Number=Sing	_	_	_	_
16	complex	_	NOUN	_	Number=Sing	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	comigrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	least	_	ADV	_	Degree=Sup	_	_	_	_
22	retarded	_	ADJ	_	Degree=Pos	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	GH3	_	PROPN	_	Number=Sing	_	_	_	_
27	NE	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	while	_	SCONJ	_	_	_	_	_	_
30	TR	_	PROPN	_	Number=Sing	_	_	_	_
31	beta	_	NOUN	_	Number=Sing	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
35	complexes	_	NOUN	_	Number=Plur	_	_	_	_
36	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
37	that	_	SCONJ	_	_	_	_	_	_
38	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
39	can	_	AUX	_	VerbForm=Fin	_	_	_	_
40	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	TREp	_	PROPN	_	Number=Sing	_	_	_	_
43	as	_	ADP	_	_	_	_	_	_
44	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
45	oligomer	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	coincubation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	35S	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	TR	_	NOUN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	GH3	_	NOUN	_	Number=Sing	_	_	_	_
12	NE	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	unlabeled	_	ADJ	_	Degree=Pos	_	_	_	_
16	TREp	_	PROPN	_	Number=Sing	_	_	_	_
17	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	not	_	ADV	_	_	_	_	_	_
20	only	_	ADV	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	35S	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	TR	_	NOUN	_	Number=Sing	_	_	_	_
25	:	_	PUNCT	_	_	_	_	_	_
26	TREp	_	NOUN	_	Number=Sing	_	_	_	_
27	complex	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	two	_	NUM	_	NumType=Card	_	_	_	_
32	additional	_	ADJ	_	Degree=Pos	_	_	_	_
33	more	_	ADV	_	_	_	_	_	_
34	greatly	_	ADV	_	_	_	_	_	_
35	retarded	_	ADJ	_	Degree=Pos	_	_	_	_
36	complexes	_	NOUN	_	Number=Plur	_	_	_	_
37	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
38	35S	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	TR	_	NOUN	_	Number=Sing	_	_	_	_
41	alpha	_	NOUN	_	Number=Sing	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	comigrating	_	VERB	_	VerbForm=Ger	_	_	_	_
45	with	_	ADP	_	_	_	_	_	_
46	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
47	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	by	_	ADP	_	_	_	_	_	_
49	GH3	_	PROPN	_	Number=Sing	_	_	_	_
50	extract	_	NOUN	_	Number=Sing	_	_	_	_
51	alone	_	ADV	_	_	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Incubation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	each	_	DET	_	_	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	TRs	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	NE	_	PROPN	_	Number=Sing	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	COS	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	7	_	NUM	_	NumType=Card	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	possess	_	VERB	_	VerbForm=Inf	_	_	_	_
19	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
20	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
21	TRs	_	NOUN	_	Number=Plur	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
24	T3	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	responses	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	formation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	new	_	ADJ	_	Degree=Pos	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	more	_	ADV	_	_	_	_	_	_
36	greatly	_	ADV	_	_	_	_	_	_
37	shifted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	complex	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	similar	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	heat	_	NOUN	_	Number=Sing	_	_	_	_
5	labile	_	ADJ	_	Degree=Pos	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	altered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	mobility	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	TR	_	NOUN	_	Number=Sing	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	TRE	_	PROPN	_	Number=Sing	_	_	_	_
15	complex	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	also	_	ADV	_	_	_	_	_	_
18	present	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	NE	_	PROPN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	T3	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	unresponsive	_	ADJ	_	Degree=Pos	_	_	_	_
25	JEG	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	3	_	NUM	_	NumType=Card	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	high	_	ADJ	_	Degree=Pos	_	_	_	_
3	concentration	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NE	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	all	_	DET	_	_	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	TR	_	NOUN	_	Number=Sing	_	_	_	_
11	bound	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	TREp	_	PROPN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	more	_	ADV	_	_	_	_	_	_
16	greatly	_	ADV	_	_	_	_	_	_
17	retarded	_	ADJ	_	Degree=Pos	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	absence	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NE	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Truncation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TR	_	NOUN	_	Number=Sing	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	amino	_	NOUN	_	Number=Sing	_	_	_	_
8	acid	_	PROPN	_	Number=Sing	_	_	_	_
9	210	_	NUM	_	NumType=Card	_	_	_	_
10	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	additional	_	ADJ	_	Degree=Pos	_	_	_	_
12	complex	_	ADJ	_	Degree=Pos	_	_	_	_
13	formation	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	presence	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NE	_	PROPN	_	Number=Sing	_	_	_	_
19	without	_	SCONJ	_	_	_	_	_	_
20	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	carboxyl	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	terminus	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	TRs	_	NOUN	_	Number=Sing	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	essential	_	ADJ	_	Degree=Pos	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	interaction	_	NOUN	_	Number=Sing	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
39	proteins	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	00300368	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	erythrocytic	_	ADJ	_	Degree=Pos	_	_	_	_
4	lineages	_	NOUN	_	Number=Plur	_	_	_	_
5	share	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Erythroid	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	genes	_	NOUN	_	Number=Plur	_	_	_	_
5	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	E1	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	GF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	Eryf	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	;	_	PUNCT	_	_	_	_	_	_
23	refs	_	NOUN	_	Number=Plur	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	3	_	NUM	_	NumType=Card	_	_	_	_
27	respectively	_	ADV	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	principal	_	ADJ	_	Degree=Pos	_	_	_	_
32	DNA	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	binding	_	VERB	_	Number=Sing	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	erythrocytic	_	ADJ	_	Degree=Pos	_	_	_	_
39	lineage	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	E1	_	PROPN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	erythrocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	lineage	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	closely	_	ADV	_	_	_	_	_	_
3	related	_	ADJ	_	Degree=Pos	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	if	_	SCONJ	_	_	_	_	_	_
6	not	_	ADV	_	_	_	_	_	_
7	identical	_	ADJ	_	Degree=Pos	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	line	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	megakaryocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	;	_	PUNCT	_	_	_	_	_	_
24	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
25	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	promoter	_	VERB	_	VerbForm=Inf	_	_	_	_
28	regions	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	two	_	NUM	_	NumType=Card	_	_	_	_
31	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	specific	_	ADJ	_	Degree=Pos	_	_	_	_
34	genes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	sites	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	partial	_	ADJ	_	Degree=Pos	_	_	_	_
6	proteolysis	_	ADJ	_	Number=Sing	_	_	_	_
7	profile	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	indistinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	;	_	PUNCT	_	_	_	_	_	_
20	also	_	ADV	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	E1	_	PROPN	_	Number=Sing	_	_	_	_
25	messenger	_	NOUN	_	Number=Sing	_	_	_	_
26	RNA	_	PROPN	_	Number=Sing	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	same	_	ADJ	_	Degree=Pos	_	_	_	_
30	size	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	both	_	CCONJ	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	lines	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	point	_	NOUN	_	Number=Sing	_	_	_	_
4	mutations	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	abolish	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	E1	_	NOUN	_	Number=Sing	_	_	_	_
12	result	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	70	_	NUM	_	NumType=Card	_	_	_	_
16	%	_	SYM	_	Number=Sing	_	_	_	_
17	decrease	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	E2	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	another	_	DET	_	_	_	_	_	_
10	trans	_	NOUN	_	Number=Plur	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	erythrocytic	_	ADJ	_	Degree=Pos	_	_	_	_
17	lineage	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	present	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	megakaryocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	both	_	DET	_	_	_	_	_	_
5	lineages	_	NOUN	_	Number=Plur	_	_	_	_
6	might	_	AUX	_	VerbForm=Fin	_	_	_	_
7	then	_	ADV	_	PronType=Dem	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	part	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	same	_	ADJ	_	Degree=Pos	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	trans	_	NOUN	_	Number=Plur	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	acting	_	NOUN	_	Number=Sing	_	_	_	_
19	factors	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	strengthen	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	idea	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	close	_	ADJ	_	Degree=Pos	_	_	_	_
9	association	_	NOUN	_	Number=Sing	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	erythrocytic	_	ADJ	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	lineages	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	could	_	AUX	_	VerbForm=Fin	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	markers	_	NOUN	_	Number=Plur	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	erythrocytic	_	ADJ	_	Degree=Pos	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
31	lineages	_	NOUN	_	Number=Plur	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	most	_	ADJ	_	_	_	_	_	_
34	erythroblastic	_	ADJ	_	Degree=Pos	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	megakaryoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
37	permanent	_	ADJ	_	Degree=Pos	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	lines	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300370	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	decreases	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	increases	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	dexamethasone	_	VERB	_	Number=Sing	_	_	_	_
20	:	_	PUNCT	_	_	_	_	_	_
21	potential	_	ADJ	_	Degree=Pos	_	_	_	_
22	regulation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Resistance	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
4	therapy	_	NOUN	_	Number=Sing	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	patients	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	autoimmune	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	diseases	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	related	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	process	_	NOUN	_	Number=Sing	_	_	_	_
23	itself	_	PRON	_	Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	aim	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	ability	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	tumor	_	NOUN	_	Number=Sing	_	_	_	_
13	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	10	_	NUM	_	NumType=Card	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
33	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	differentially	_	ADV	_	_	_	_	_	_
37	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	human	_	ADJ	_	Degree=Pos	_	_	_	_
42	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
43	/	_	PUNCT	_	_	_	_	_	_
44	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	accomplish	_	VERB	_	VerbForm=Inf	_	_	_	_
3	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	first	_	ADV	_	_	_	_	_	_
7	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	pattern	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	10	_	NUM	_	NumType=Card	_	_	_	_
16	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	LPS	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	whole	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	blood	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	cultures	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Second	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	modulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	dexamethasone	_	VERB	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	preincubation	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	10	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	measurement	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	LPS	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	6	_	NUM	_	NumType=Card	_	_	_	_
32	secretion	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	evaluated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	phorbolmyristate	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	acetate	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
21	secretion	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	line	_	NOUN	_	Number=Sing	_	_	_	_
28	U937	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	whether	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	modulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	corticosensitivity	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	10	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	pretreated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	U937	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	related	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	change	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	concentration	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	affinity	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Dexamethasone	_	PROPN	_	Number=Sing	_	_	_	_
2	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	different	_	ADJ	_	Degree=Pos	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	LPS	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	10	_	NUM	_	NumType=Card	_	_	_	_
14	secretion	_	NOUN	_	Number=Sing	_	_	_	_
15	;	_	PUNCT	_	_	_	_	_	_
16	whereas	_	SCONJ	_	_	_	_	_	_
17	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
18	suppressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	dose	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
25	fashion	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	effect	_	NOUN	_	Number=Sing	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	10	_	NUM	_	NumType=Card	_	_	_	_
33	secretion	_	NOUN	_	Number=Sing	_	_	_	_
34	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
35	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
38	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
39	at	_	ADP	_	_	_	_	_	_
40	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
44	at	_	ADP	_	_	_	_	_	_
45	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
46	doses	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	concentration	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	LPS	_	NOUN	_	Number=Sing	_	_	_	_
5	employed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	influenced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	effect	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	10	_	NUM	_	NumType=Card	_	_	_	_
15	secretion	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	P	_	NOUN	_	Number=Sing	_	_	_	_
18	<	_	PUNCT	_	_	_	_	_	_
19	0.001	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
4	diminished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	improved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	ability	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	6	_	NUM	_	NumType=Card	_	_	_	_
22	secretion	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	whole	_	ADJ	_	Degree=Pos	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	blood	_	NOUN	_	Number=Sing	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	cultures	_	NOUN	_	Number=Plur	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	P	_	NOUN	_	Number=Sing	_	_	_	_
31	<	_	PUNCT	_	_	_	_	_	_
32	0.01	_	NUM	_	NumType=Card	_	_	_	_
33	for	_	ADP	_	_	_	_	_	_
34	both	_	DET	_	_	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	to	_	PART	_	_	_	_	_	_
38	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	receptor	_	NOUN	_	Number=Sing	_	_	_	_
43	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
44	secretion	_	NOUN	_	Number=Sing	_	_	_	_
45	by	_	ADP	_	_	_	_	_	_
46	U937	_	NUM	_	Number=Sing	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	P	_	NOUN	_	Number=Sing	_	_	_	_
50	<	_	PUNCT	_	_	_	_	_	_
51	0.05	_	NUM	_	NumType=Card	_	_	_	_
52	for	_	ADP	_	_	_	_	_	_
53	both	_	DET	_	_	_	_	_	_
54	)	_	PUNCT	_	_	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
2	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	P	_	NOUN	_	Number=Sing	_	_	_	_
5	<	_	PUNCT	_	_	_	_	_	_
6	0.001	_	NUM	_	NumType=Card	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	while	_	SCONJ	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	10	_	NUM	_	NumType=Card	_	_	_	_
13	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	P	_	NOUN	_	Number=Sing	_	_	_	_
16	<	_	PUNCT	_	_	_	_	_	_
17	0.001	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	concentration	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
24	binding	_	VERB	_	Number=Sing	_	_	_	_
25	sites	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	no	_	DET	_	_	_	_	_	_
32	discernible	_	ADJ	_	Degree=Pos	_	_	_	_
33	effect	_	NOUN	_	Number=Sing	_	_	_	_
34	on	_	ADP	_	_	_	_	_	_
35	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
36	binding	_	NOUN	_	Number=Sing	_	_	_	_
37	affinity	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
5	differentially	_	ADV	_	_	_	_	_	_
6	modulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	10	_	NUM	_	NumType=Card	_	_	_	_
12	secretion	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	LPS	_	NOUN	_	Number=Sing	_	_	_	_
19	dose	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	fashion	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	glucocorticoids	_	NOUN	_	Number=Sing	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
36	or	_	CCONJ	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	10	_	NUM	_	NumType=Card	_	_	_	_
40	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
41	;	_	PUNCT	_	_	_	_	_	_
42	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
43	blocks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
44	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
45	effects	_	NOUN	_	Number=Plur	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	whereas	_	SCONJ	_	_	_	_	_	_
48	IL	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	10	_	NUM	_	NumType=Card	_	_	_	_
51	acts	_	NOUN	_	Number=Plur	_	_	_	_
52	synergistically	_	ADV	_	_	_	_	_	_
53	with	_	ADP	_	_	_	_	_	_
54	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	opposite	_	ADJ	_	Degree=Pos	_	_	_	_
6	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	changes	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	respectively	_	ADV	_	_	_	_	_	_
11	opposing	_	ADJ	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	favoring	_	VERB	_	VerbForm=Ger	_	_	_	_
14	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
15	actions	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	pattern	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	pro-/antiinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	secretion	_	NOUN	_	Number=Sing	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	patients	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	glucocorticoid	_	VERB	_	Degree=Pos	_	_	_	_
19	therapy	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300379	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CD14	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	VERB	_	Degree=Pos	_	_	_	_
4	signal	_	ADJ	_	Number=Sing	_	_	_	_
5	pathway	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Porphyromonas	_	PROPN	_	Degree=Pos	_	_	_	_
8	gingivalis	_	PROPN	_	Degree=Pos	_	_	_	_
9	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	gingival	_	NOUN	_	Degree=Pos	_	_	_	_
13	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Lipopolysaccharide	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	LPS	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
14	via	_	ADP	_	_	_	_	_	_
15	CD14	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	one	_	NUM	_	NumType=Card	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	LPS	_	NOUN	_	Number=Sing	_	_	_	_
21	receptors	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	predominantly	_	ADV	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	Porphyromonas	_	PROPN	_	Number=Sing	_	_	_	_
7	gingivalis	_	NOUN	_	Number=Sing	_	_	_	_
8	LPS	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	P	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	LPS	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	able	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
19	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
20	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	gingival	_	NOUN	_	Degree=Pos	_	_	_	_
24	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
8	whether	_	SCONJ	_	_	_	_	_	_
9	CD14	_	PROPN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	gingival	_	ADJ	_	Degree=Pos	_	_	_	_
14	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	define	_	VERB	_	VerbForm=Inf	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	P-LPS	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	VERB	_	Degree=Pos	_	_	_	_
22	signal	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	transducing	_	VERB	_	Number=Sing	_	_	_	_
25	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	unexpectedly	_	ADV	_	_	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	immunohistochemical	_	ADJ	_	Degree=Pos	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	Western	_	ADJ	_	Degree=Pos	_	_	_	_
12	blotting	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	immunoblotting	_	ADJ	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	Northern	_	ADJ	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	RNA	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	blotting	_	VERB	_	Number=Sing	_	_	_	_
23	assays	_	NOUN	_	Number=Plur	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	CD14	_	PROPN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	at	_	ADP	_	_	_	_	_	_
29	high	_	ADJ	_	Degree=Pos	_	_	_	_
30	density	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	human	_	ADJ	_	Degree=Pos	_	_	_	_
33	gingival	_	NOUN	_	Number=Sing	_	_	_	_
34	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	P-LPS	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
8	chemoattractant	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	MCP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	markedly	_	ADV	_	_	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	treatment	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	anti-human	_	ADJ	_	Degree=Pos	_	_	_	_
27	CD14	_	PROPN	_	Number=Sing	_	_	_	_
28	antibody	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
31	completely	_	ADV	_	_	_	_	_	_
32	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	herbimycin	_	NOUN	_	Number=Sing	_	_	_	_
35	A	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	potent	_	ADJ	_	Degree=Pos	_	_	_	_
39	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
42	kinase	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	dramatically	_	ADV	_	_	_	_	_	_
5	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
7	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	MCP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	P-LPS	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	MCP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	also	_	ADV	_	_	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	two	_	NUM	_	NumType=Card	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factors	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	i.e.	_	X	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	curcumin	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	AP	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	pyrolidine	_	NOUN	_	Number=Sing	_	_	_	_
39	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	NF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
3	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
5	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	culture	_	NOUN	_	Number=Sing	_	_	_	_
10	supernatant	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	P-LPS	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	shift	_	NOUN	_	Number=Sing	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	contents	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	P-LPS	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	demonstrate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	CD14	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	gingival	_	NOUN	_	Degree=Pos	_	_	_	_
15	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	show	_	VERB	_	VerbForm=Inf	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	signal	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	transducing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	pathway	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	P	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	LPS	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	CD14	_	PROPN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300384	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	UV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	CYP1A1	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	tryptophan	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cytochrome	_	NOUN	_	Number=Sing	_	_	_	_
4	P	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	4501A1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	CYP1A1	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	UV	_	PROPN	_	Number=Sing	_	_	_	_
13	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
15	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	earlier	_	ADV	_	Degree=Cmp	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	animal	_	NOUN	_	Number=Sing	_	_	_	_
19	studies	_	NOUN	_	Number=Plur	_	_	_	_
20	via	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	yet	_	ADV	_	_	_	_	_	_
27	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
28	resolved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	previous	_	ADJ	_	Degree=Pos	_	_	_	_
3	data	_	NOUN	_	Number=Sing	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	indicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	formylated	_	ADJ	_	Degree=Pos	_	_	_	_
8	indolocarbazoles	_	NOUN	_	Number=Plur	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	formed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	UV	_	PROPN	_	Number=Sing	_	_	_	_
14	irradiation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	tryptophan	_	ADJ	_	Degree=Pos	_	_	_	_
17	solutions	_	NOUN	_	Number=Plur	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	very	_	ADV	_	_	_	_	_	_
20	potent	_	ADJ	_	Degree=Pos	_	_	_	_
21	Ah	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	agonists	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	evaluate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	UV	_	PROPN	_	Number=Sing	_	_	_	_
7	light	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	cytochrome	_	NOUN	_	Number=Sing	_	_	_	_
10	P4501A1	_	NUM	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	CYP1A1	_	NOUN	_	Number=Sing	_	_	_	_
20	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	UV	_	PROPN	_	Number=Sing	_	_	_	_
23	irradiation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	cultured	_	VERB	_	Degree=Pos	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	keratinocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	HaCaT	_	ADJ	_	Degree=Pos	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	line	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	primary	_	ADJ	_	Degree=Pos	_	_	_	_
35	human	_	ADJ	_	Degree=Pos	_	_	_	_
36	blood	_	NOUN	_	Number=Sing	_	_	_	_
37	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	mouse	_	NOUN	_	Number=Sing	_	_	_	_
40	Hepa	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	exposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	UV	_	PROPN	_	Number=Sing	_	_	_	_
7	light	_	NOUN	_	Number=Sing	_	_	_	_
8	delivered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	bank	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	Philips	_	PROPN	_	Number=Plur	_	_	_	_
15	TL20/12RS	_	NOUN	_	Number=Sing	_	_	_	_
16	sun	_	NOUN	_	Number=Sing	_	_	_	_
17	lamps	_	NOUN	_	Number=Plur	_	_	_	_
18	emitting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	primarily	_	ADV	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	UVB	_	NOUN	_	Number=Sing	_	_	_	_
23	range	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	absence	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	presence	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	tryptophan	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	semiquantitative	_	ADJ	_	Degree=Pos	_	_	_	_
3	reverse	_	NOUN	_	Number=Sing	_	_	_	_
4	transcriptase	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
8	chain	_	NOUN	_	Number=Sing	_	_	_	_
9	reaction	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	RT	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	PCR	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	analysis	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	CYP1A1	_	PROPN	_	Number=Sing	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	level	_	NOUN	_	Number=Sing	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	UV	_	PROPN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	presence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	tryptophan	_	PROPN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
19	than	_	SCONJ	_	_	_	_	_	_
20	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	UV	_	PROPN	_	Number=Sing	_	_	_	_
24	alone	_	ADV	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	both	_	CCONJ	_	_	_	_	_	_
27	HaCaT	_	ADJ	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
31	after	_	ADP	_	_	_	_	_	_
32	3	_	NUM	_	NumType=Card	_	_	_	_
33	h	_	NOUN	_	Number=Plur	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	incubation	_	NOUN	_	Number=Sing	_	_	_	_
36	post-UV	_	ADJ	_	Number=Sing	_	_	_	_
37	irradiation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	find	_	VERB	_	VerbForm=Inf	_	_	_	_
3	out	_	ADP	_	_	_	_	_	_
4	if	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	UV	_	PROPN	_	Number=Sing	_	_	_	_
9	light	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	caused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	formation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	Ah	_	PROPN	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	ligand	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	Hepa	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	wild	_	ADJ	_	Degree=Pos	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	type	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	Ah	_	NOUN	_	Number=Sing	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
31	c12	_	NOUN	_	NumType=Card	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	lines	_	NOUN	_	Number=Plur	_	_	_	_
34	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	applied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Wild	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	type	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	wt	_	X	_	Degree=Pos	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
10	either	_	CCONJ	_	_	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	tryptophan	_	NOUN	_	Number=Sing	_	_	_	_
14	photoproduct	_	NOUN	_	Number=Sing	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	formylindolo	_	NOUN	_	Number=Sing	_	_	_	_
18	[	_	PUNCT	_	_	_	_	_	_
19	3,2-	_	NUM	_	NumType=Card	_	_	_	_
20	b]carbazole	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	FICZ	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	UV	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	irradiation	_	NOUN	_	Number=Sing	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	very	_	ADV	_	_	_	_	_	_
31	low	_	ADJ	_	Degree=Pos	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	undetectable	_	ADJ	_	Degree=Pos	_	_	_	_
34	levels	_	NOUN	_	Number=Plur	_	_	_	_
35	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	c12	_	NOUN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	FICZ	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	UV	_	PROPN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	Ah	_	DET	_	_	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	UV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	CYP1A1	_	PROPN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	Ah	_	PROPN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	ligand	_	NOUN	_	Number=Sing	_	_	_	_
23	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	tryptophan	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	photoproducts	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	tryptophan	_	NOUN	_	Number=Sing	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	mediators	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	light	_	NOUN	_	Number=Sing	_	_	_	_
14	via	_	ADP	_	_	_	_	_	_
15	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	Ah	_	PROPN	_	Number=Sing	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	as	_	SCONJ	_	_	_	_	_	_
22	such	_	ADJ	_	Degree=Pos	_	_	_	_
23	also	_	ADV	_	_	_	_	_	_
24	could	_	AUX	_	VerbForm=Fin	_	_	_	_
25	have	_	VERB	_	VerbForm=Inf	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	role	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	light	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	biological	_	ADJ	_	Degree=Pos	_	_	_	_
33	rhythms	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300385	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Ah	_	PROPN	_	Number=Sing	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	BSAP	_	PROPN	_	Number=Sing	_	_	_	_
16	:	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	possible	_	ADJ	_	Degree=Pos	_	_	_	_
19	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	dioxin	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
24	alteration	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	CD19	_	PROPN	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	2,3,7,8-tetrachlorodibenzo-p-dioxin	_	NOUN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	TCDD	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	inhibits	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	murine	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	through	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
16	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	TCDD	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	CD19	_	PROPN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	line	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	PROPN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	TCDD	_	ADJ	_	Number=Sing	_	_	_	_
7	treatment	_	NOUN	_	Number=Sing	_	_	_	_
8	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	steady	_	ADJ	_	Degree=Pos	_	_	_	_
10	state	_	NOUN	_	Number=Sing	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	CD19	_	PROPN	_	Number=Sing	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	67	_	NUM	_	NumType=Card	_	_	_	_
17	%	_	SYM	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	IM	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	9	_	NUM	_	NumType=Card	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	line	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	gel	_	NOUN	_	Number=Sing	_	_	_	_
4	mobility	_	NOUN	_	Number=Sing	_	_	_	_
5	shift	_	NOUN	_	Number=Sing	_	_	_	_
6	assay	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	complex	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	IM	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	9	_	NUM	_	NumType=Card	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	extracts	_	NOUN	_	Number=Plur	_	_	_	_
21	that	_	PRON	_	_	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	several	_	ADJ	_	Degree=Pos	_	_	_	_
24	criteria	_	NOUN	_	Number=Sing	_	_	_	_
25	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	Ah	_	NOUN	_	Number=Sing	_	_	_	_
30	receptor	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	Ah	_	PROPN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	complex	_	NOUN	_	Number=Sing	_	_	_	_
8	recognized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	DNA	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	B	_	ADJ	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	lineage	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	activator	_	NOUN	_	Number=Sing	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	BSAP	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	promoter	_	ADJ	_	Number=Sing	_	_	_	_
27	region	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	CD19	_	PROPN	_	Number=Sing	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	which	_	PRON	_	PronType=Rel	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	similar	_	ADJ	_	Degree=Pos	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	consensus	_	NOUN	_	Number=Sing	_	_	_	_
39	Ah	_	PROPN	_	Number=Sing	_	_	_	_
40	receptor	_	NOUN	_	Number=Sing	_	_	_	_
41	DNA	_	PROPN	_	Number=Sing	_	_	_	_
42	binding	_	NOUN	_	Number=Sing	_	_	_	_
43	site	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	AhR	_	PROPN	_	Number=Sing	_	_	_	_
7	could	_	AUX	_	VerbForm=Fin	_	_	_	_
8	interfere	_	VERB	_	VerbForm=Inf	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	BSAP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	CD19	_	PROPN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	competition	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	common	_	ADJ	_	Degree=Pos	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300387	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	growth	_	NOUN	_	Number=Sing	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	after	_	ADP	_	_	_	_	_	_
9	treatment	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	arsenic	_	NOUN	_	Degree=Pos	_	_	_	_
12	trioxide	_	NOUN	_	Number=Sing	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	clinically	_	ADV	_	_	_	_	_	_
15	achievable	_	ADJ	_	Degree=Pos	_	_	_	_
16	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
17	[	_	PUNCT	_	_	_	_	_	_
18	see	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
19	comments	_	NOUN	_	Number=Plur	_	_	_	_
20	]	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Arsenic	_	ADJ	_	Number=Sing	_	_	_	_
4	trioxide	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	As2O3	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
10	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
11	remission	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	patients	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	acute	_	ADJ	_	Degree=Pos	_	_	_	_
16	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
17	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
18	via	_	ADP	_	_	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	programmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	death	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	As2O3	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	panel	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
15	whether	_	SCONJ	_	_	_	_	_	_
16	growth	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
21	effects	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	As2O3	_	NOUN	_	Number=Sing	_	_	_	_
24	can	_	AUX	_	VerbForm=Fin	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	at	_	ADP	_	_	_	_	_	_
31	clinically	_	ADV	_	_	_	_	_	_
32	achievable	_	ADJ	_	Degree=Pos	_	_	_	_
33	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Eight	_	NUM	_	NumType=Card	_	_	_	_
4	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
5	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	lines	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	cultures	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
13	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	As2O3	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	without	_	ADP	_	_	_	_	_	_
25	dithiothreitol	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	DTT	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	buthionine	_	NOUN	_	Number=Sing	_	_	_	_
31	sulfoximine	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	BSO	_	PROPN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
40	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Apoptosis	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	morphology	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	flow	_	NOUN	_	Number=Sing	_	_	_	_
9	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	annexin	_	NOUN	_	Number=Sing	_	_	_	_
12	V	_	NOUN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	level	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	terminal	_	ADJ	_	Number=Sing	_	_	_	_
18	deoxynucleotidyl	_	NOUN	_	Number=Sing	_	_	_	_
19	transferase	_	NOUN	_	Number=Sing	_	_	_	_
20	labeling	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	DNA	_	NOUN	_	Number=Sing	_	_	_	_
23	fragments	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Cellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	5	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	bromo	_	NOUN	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	'-	_	PUNCT	_	_	_	_	_	_
12	deoxyuridine	_	NOUN	_	Number=Sing	_	_	_	_
13	incorporation	_	NOUN	_	Number=Sing	_	_	_	_
14	into	_	ADP	_	_	_	_	_	_
15	DNA	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	flow	_	VERB	_	Number=Sing	_	_	_	_
18	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	use	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	mitotic	_	ADJ	_	Degree=Pos	_	_	_	_
25	arrest	_	NOUN	_	Number=Sing	_	_	_	_
26	assay	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Mitochondrial	_	ADJ	_	Number=Sing	_	_	_	_
2	transmembrane	_	NOUN	_	Number=Sing	_	_	_	_
3	potential	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	delta	_	NOUN	_	Number=Sing	_	_	_	_
6	psi	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	m	_	NOUN	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	means	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	rhodamine	_	NOUN	_	Number=Sing	_	_	_	_
17	123	_	NUM	_	NumType=Card	_	_	_	_
18	staining	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	flow	_	NOUN	_	Number=Sing	_	_	_	_
21	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	western	_	ADJ	_	Degree=Pos	_	_	_	_
7	blot	_	NOUN	_	Number=Sing	_	_	_	_
8	analysis	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	Therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
2	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	As2O3	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	microM	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	dual	_	ADJ	_	Degree=Pos	_	_	_	_
13	effects	_	NOUN	_	Number=Plur	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	:	_	PUNCT	_	_	_	_	_	_
18	1	_	X	_	_	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	growth	_	NOUN	_	Number=Sing	_	_	_	_
23	through	_	ADP	_	_	_	_	_	_
24	adenosine	_	NOUN	_	Degree=Pos	_	_	_	_
25	triphosphate	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	ATP	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	depletion	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	prolongation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	cycle	_	NOUN	_	Number=Sing	_	_	_	_
35	time	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	induction	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	As2O3	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	preceded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	delta	_	NOUN	_	Number=Sing	_	_	_	_
9	psi	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	m	_	NOUN	_	NumType=Card	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	collapse	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	DTT	_	PROPN	_	Number=Sing	_	_	_	_
2	antagonized	_	VERB	_	Degree=Pos	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	BSO	_	PROPN	_	Number=Sing	_	_	_	_
5	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	As2O3	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	ATP	_	NOUN	_	Number=Sing	_	_	_	_
10	depletion	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	delta	_	NOUN	_	Number=Sing	_	_	_	_
13	psi	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	m	_	NOUN	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	collapse	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Caspase	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	usually	_	ADV	_	_	_	_	_	_
7	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	delta	_	NOUN	_	Number=Sing	_	_	_	_
10	psi	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	m	_	NOUN	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	collapse	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	always	_	ADV	_	_	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	As2O3	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	As2O3	_	NOUN	_	Number=Sing	_	_	_	_
2	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	PML	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
6	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	degradation	_	NOUN	_	Number=Sing	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	cycle	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	related	_	ADJ	_	Degree=Pos	_	_	_	_
20	proteins	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	including	_	VERB	_	VerbForm=Ger	_	_	_	_
23	c-myc	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
31	kinase	_	NOUN	_	Number=Sing	_	_	_	_
32	4	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
35	D1	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	p53	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	or	_	CCONJ	_	_	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	related	_	ADJ	_	Degree=Pos	_	_	_	_
46	antigens	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Substantial	_	ADJ	_	Degree=Pos	_	_	_	_
4	growth	_	NOUN	_	Number=Sing	_	_	_	_
5	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
8	without	_	ADP	_	_	_	_	_	_
9	evidence	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	most	_	ADV	_	_	_	_	_	_
16	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
17	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	SYM	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	microM	_	NOUN	_	Number=Sing	_	_	_	_
25	As2O3	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	As2O3	_	PROPN	_	Number=Sing	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	prove	_	VERB	_	VerbForm=Inf	_	_	_	_
4	useful	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	treatment	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
10	lymphoproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
11	disorders	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300389	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Legionella	_	PROPN	_	Number=Sing	_	_	_	_
3	pneumophila	_	NOUN	_	Number=Sing	_	_	_	_
4	rpoS	_	NOUN	_	Degree=Pos	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	growth	_	NOUN	_	Number=Sing	_	_	_	_
10	within	_	ADP	_	_	_	_	_	_
11	Acanthamoeba	_	PROPN	_	Number=Sing	_	_	_	_
12	castellanii	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	networks	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	Legionella	_	PROPN	_	Number=Sing	_	_	_	_
7	pneumophila	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	homolog	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	Escherichia	_	PROPN	_	Number=Sing	_	_	_	_
17	coli	_	NOUN	_	Number=Sing	_	_	_	_
18	stress	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	stationary	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	phase	_	NOUN	_	Number=Sing	_	_	_	_
23	sigma	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	RpoS	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	complementation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	E.	_	PROPN	_	Number=Sing	_	_	_	_
33	coli	_	NOUN	_	Number=Sing	_	_	_	_
34	rpoS	_	NOUN	_	Number=Sing	_	_	_	_
35	mutation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	open	_	ADJ	_	Degree=Pos	_	_	_	_
3	reading	_	NOUN	_	Number=Sing	_	_	_	_
4	frame	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	approximately	_	ADV	_	_	_	_	_	_
8	60	_	NUM	_	NumType=Card	_	_	_	_
9	%	_	SYM	_	Number=Sing	_	_	_	_
10	identical	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	E.	_	PROPN	_	Number=Sing	_	_	_	_
14	coli	_	NOUN	_	Number=Sing	_	_	_	_
15	rpoS	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	level	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	L.	_	PROPN	_	Number=Sing	_	_	_	_
10	pneumophila	_	PROPN	_	Number=Sing	_	_	_	_
11	RpoS	_	NOUN	_	Number=Sing	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	stationary	_	ADJ	_	Degree=Pos	_	_	_	_
15	phase	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	insertion	_	NOUN	_	Number=Sing	_	_	_	_
3	mutation	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	constructed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	rpoS	_	NOUN	_	Degree=Pos	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	L.	_	PROPN	_	Number=Sing	_	_	_	_
15	pneumophila	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	ability	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	mutant	_	NOUN	_	Number=Sing	_	_	_	_
23	strain	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	survive	_	VERB	_	VerbForm=Inf	_	_	_	_
26	various	_	ADJ	_	Degree=Pos	_	_	_	_
27	stress	_	NOUN	_	Number=Sing	_	_	_	_
28	conditions	_	NOUN	_	Number=Plur	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	assayed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	results	_	NOUN	_	Number=Plur	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	wild	_	ADJ	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	type	_	NOUN	_	Number=Sing	_	_	_	_
40	strain	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	mutant	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	wild	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	strains	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	more	_	ADV	_	_	_	_	_	_
11	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	stress	_	VERB	_	VerbForm=Inf	_	_	_	_
14	when	_	ADV	_	PronType=Int	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	stationary	_	ADJ	_	Degree=Pos	_	_	_	_
17	phase	_	NOUN	_	Number=Sing	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	when	_	ADV	_	PronType=Int	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	logarithmic	_	ADJ	_	Degree=Pos	_	_	_	_
23	phase	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	growth	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	finding	_	NOUN	_	Number=Sing	_	_	_	_
3	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	L.	_	PROPN	_	Number=Sing	_	_	_	_
6	pneumophila	_	PROPN	_	Number=Sing	_	_	_	_
7	RpoS	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	stationary	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	phase	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	resistance	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	stress	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	mutant	_	NOUN	_	Number=Sing	_	_	_	_
4	strain	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	able	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	kill	_	VERB	_	VerbForm=Inf	_	_	_	_
9	HL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	60	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	THP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	could	_	AUX	_	VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
25	within	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	protozoan	_	NOUN	_	Degree=Pos	_	_	_	_
28	host	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	Acanthamoeba	_	PROPN	_	Number=Sing	_	_	_	_
31	castellanii	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	L.	_	PROPN	_	Number=Sing	_	_	_	_
6	pneumophila	_	PROPN	_	Number=Sing	_	_	_	_
7	possesses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	growth	_	NOUN	_	Number=Sing	_	_	_	_
10	phase	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	resistance	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	stress	_	NOUN	_	VerbForm=Inf	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	independent	_	ADJ	_	Degree=Pos	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	RpoS	_	PROPN	_	Number=Sing	_	_	_	_
21	control	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	RpoS	_	PROPN	_	Number=Sing	_	_	_	_
25	likely	_	ADV	_	_	_	_	_	_
26	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	genes	_	NOUN	_	Number=Plur	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	enable	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	survive	_	VERB	_	VerbForm=Inf	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	environment	_	NOUN	_	Number=Sing	_	_	_	_
36	within	_	ADP	_	_	_	_	_	_
37	protozoa	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	rpoS	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	L.	_	PROPN	_	Number=Sing	_	_	_	_
11	pneumophila	_	PROPN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	very	_	ADV	_	_	_	_	_	_
14	different	_	ADJ	_	Degree=Pos	_	_	_	_
15	from	_	SCONJ	_	_	_	_	_	_
16	what	_	PRON	_	PronType=Int	_	_	_	_
17	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	previously	_	ADV	_	_	_	_	_	_
19	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
20	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	E.	_	PROPN	_	Number=Sing	_	_	_	_
23	coli	_	NOUN	_	Number=Sing	_	_	_	_
24	rpoS	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300390	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Modulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CD28	_	PROPN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	:	_	PUNCT	_	_	_	_	_	_
6	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
7	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	pathways	_	NOUN	_	Number=Plur	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	replicative	_	ADJ	_	Degree=Pos	_	_	_	_
13	senescence	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	molecule	_	NOUN	_	Number=Sing	_	_	_	_
4	CD28	_	PROPN	_	Number=Sing	_	_	_	_
5	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	tissue	_	NOUN	_	Number=Sing	_	_	_	_
9	distribution	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	some	_	DET	_	_	_	_	_	_
18	plasmacytoma	_	ADJ	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	CD28	_	PROPN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	constitutively	_	ADV	_	_	_	_	_	_
5	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	transiently	_	ADV	_	_	_	_	_	_
11	down	_	ADV	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	following	_	VERB	_	VerbForm=Ger	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	declines	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	progressively	_	ADV	_	_	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	vitro	_	ADJ	_	Degree=Pos	_	_	_	_
24	senescence	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	CD8	_	PROPN	_	Number=Sing	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_

1	T	_	X	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	less	_	ADV	_	Degree=Cmp	_	_	_	_
6	frequently	_	ADV	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	CD4	_	PROPN	_	Number=Sing	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	may	_	AUX	_	VerbForm=Fin	_	_	_	_
4	completely	_	ADV	_	_	_	_	_	_
5	lose	_	VERB	_	VerbForm=Inf	_	_	_	_
6	CD28	_	PROPN	_	Number=Sing	_	_	_	_
7	surface	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
11	infections	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	aging	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	changes	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	activities	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	two	_	NUM	_	NumType=Card	_	_	_	_
13	motifs	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	beta	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	within	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	CD28	_	NOUN	_	Number=Sing	_	_	_	_
23	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	alpha	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	beta-bound	_	NOUN	_	Number=Sing	_	_	_	_
6	complexes	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	only	_	ADV	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
12	tissues	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	CD28	_	NOUN	_	Number=Sing	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	some	_	DET	_	_	_	_	_	_
7	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	complexes	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	coordinately	_	ADV	_	_	_	_	_	_
5	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	except	_	ADP	_	_	_	_	_	_
7	during	_	ADP	_	_	_	_	_	_
8	replicative	_	ADJ	_	Degree=Pos	_	_	_	_
9	senescence	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	down	_	ADJ	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	modulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	beta	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	binding	_	VERB	_	Number=Sing	_	_	_	_
29	activities	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	T	_	NOUN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	parallel	_	ADJ	_	Degree=Pos	_	_	_	_
10	decline	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	both	_	DET	_	_	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	beta-binding	_	NOUN	_	Number=Sing	_	_	_	_
18	activities	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	CD4	_	PROPN	_	Number=Sing	_	_	_	_
2	+	_	SYM	_	_	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	CD8	_	PROPN	_	Number=Sing	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	profiles	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	more	_	ADV	_	_	_	_	_	_
16	pronounced	_	VERB	_	Degree=Pos	_	_	_	_
17	down	_	ADP	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	CD28	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	senescent	_	ADJ	_	Degree=Pos	_	_	_	_
24	CD8	_	NOUN	_	Number=Sing	_	_	_	_
25	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	NOUN	_	Number=Sing	_	_	_	_
3	expanded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	CD4	_	NOUN	_	Number=Sing	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_
6	CD28null	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	CD8	_	NOUN	_	Number=Sing	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_
10	CD28null	_	PROPN	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	uniformly	_	ADV	_	_	_	_	_	_
14	lack	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	beta	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	bound	_	ADJ	_	Degree=Pos	_	_	_	_
21	complexes	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	resembling	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	pattern	_	NOUN	_	Number=Sing	_	_	_	_
26	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	chronically	_	ADV	_	_	_	_	_	_
29	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	not	_	ADV	_	_	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	senescent	_	ADJ	_	Degree=Pos	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300393	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	properties	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	heat	_	NOUN	_	Number=Sing	_	_	_	_
9	shock	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	HSF1	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	HSF3	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	avian	_	ADJ	_	Degree=Pos	_	_	_	_
21	erythroblast	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	HD6	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Avian	_	ADJ	_	Degree=Pos	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	three	_	NUM	_	NumType=Card	_	_	_	_
5	heat	_	NOUN	_	Number=Sing	_	_	_	_
6	shock	_	NOUN	_	Number=Sing	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	HSF	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	genes	_	NOUN	_	Number=Plur	_	_	_	_
13	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	novel	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	HSF3	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	homologs	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	mouse	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	HSF1	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	cell	_	VERB	_	Number=Sing	_	_	_	_
7	biological	_	ADJ	_	Degree=Pos	_	_	_	_
8	properties	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	HSFs	_	NOUN	_	Number=Plur	_	_	_	_
12	reveals	_	VERB	_	Number=Plur	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	HSF3	_	NOUN	_	Number=Sing	_	_	_	_
15	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	properties	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	common	_	ADJ	_	Degree=Pos	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	HSF1	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	yet	_	ADV	_	_	_	_	_	_
26	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	features	_	NOUN	_	Number=Plur	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	both	_	DET	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	HSF3	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	constitutively	_	ADV	_	_	_	_	_	_
4	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	erythroblast	_	NOUN	_	Degree=Pos	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	line	_	NOUN	_	Number=Sing	_	_	_	_
10	HD6	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	lymphoblast	_	ADJ	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	line	_	NOUN	_	Number=Sing	_	_	_	_
16	MSB	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	embryo	_	NOUN	_	Number=Sing	_	_	_	_
20	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	yet	_	ADV	_	_	_	_	_	_
24	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	DNA	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	only	_	ADV	_	_	_	_	_	_
32	upon	_	ADP	_	_	_	_	_	_
33	exposure	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	HD6	_	NUM	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	heat	_	NOUN	_	Number=Sing	_	_	_	_
39	shock	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Acquisition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HSF3	_	NOUN	_	Number=Sing	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	HD6	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	oligomerization	_	NOUN	_	Number=Sing	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	non-DNA	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	dimer	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	DNA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	binding	_	VERB	_	Number=Sing	_	_	_	_
26	trimer	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	whereas	_	SCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	effect	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	heat	_	NOUN	_	Number=Sing	_	_	_	_
33	shock	_	NOUN	_	Number=Sing	_	_	_	_
34	on	_	ADP	_	_	_	_	_	_
35	HSF1	_	NOUN	_	Number=Sing	_	_	_	_
36	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	oligomerization	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	inert	_	ADJ	_	Degree=Pos	_	_	_	_
41	monomer	_	NOUN	_	Number=Sing	_	_	_	_
42	to	_	ADP	_	_	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	DNA	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	binding	_	VERB	_	Number=Sing	_	_	_	_
47	trimer	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HSF3	_	NOUN	_	Number=Sing	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	delayed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	HSF1	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	HSF1	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	heat	_	NOUN	_	Number=Sing	_	_	_	_
7	shock	_	NOUN	_	Number=Sing	_	_	_	_
8	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	translocation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	HSF3	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	HSF	_	PROPN	_	Number=Sing	_	_	_	_
2	exhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	properties	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	activator	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	as	_	SCONJ	_	_	_	_	_	_
11	judged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	transiently	_	ADV	_	_	_	_	_	_
18	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
19	HSF3	_	NOUN	_	Number=Sing	_	_	_	_
20	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	SCONJ	_	_	_	_	_	_
22	using	_	VERB	_	VerbForm=Ger	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	heat	_	NOUN	_	Number=Sing	_	_	_	_
25	shock	_	NOUN	_	Number=Sing	_	_	_	_
26	element	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
29	reporter	_	NOUN	_	Number=Sing	_	_	_	_
30	construct	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	as	_	SCONJ	_	_	_	_	_	_
33	independently	_	ADV	_	_	_	_	_	_
34	assayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	activity	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	chimeric	_	ADJ	_	Degree=Pos	_	_	_	_
41	GAL4	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	HSF3	_	NOUN	_	Number=Sing	_	_	_	_
44	protein	_	NOUN	_	Number=Sing	_	_	_	_
45	on	_	ADP	_	_	_	_	_	_
46	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
47	GAL4	_	PROPN	_	Number=Sing	_	_	_	_
48	reporter	_	NOUN	_	Number=Sing	_	_	_	_
49	construct	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	HSF3	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	negatively	_	ADV	_	_	_	_	_	_
8	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	avian	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	acquires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	DNA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	certain	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	upon	_	ADP	_	_	_	_	_	_
22	heat	_	NOUN	_	Number=Sing	_	_	_	_
23	shock	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300399	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	beta	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	airway	_	NOUN	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	insensitive	_	ADJ	_	Degree=Pos	_	_	_	_
12	asthma	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	GC	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	insensitive	_	ADJ	_	Degree=Pos	_	_	_	_
7	asthma	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	challenging	_	ADJ	_	Degree=Pos	_	_	_	_
11	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
12	problem	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	life	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	threatening	_	VERB	_	VerbForm=Ger	_	_	_	_
21	disease	_	NOUN	_	Number=Sing	_	_	_	_
22	progression	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	basis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	GC	_	NOUN	_	Number=Sing	_	_	_	_
6	insensitivity	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Alternative	_	ADJ	_	Degree=Pos	_	_	_	_
2	splicing	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	GC	_	PROPN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	GCR	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	pre-mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	generates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
14	GCR	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	GCRbeta	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
23	GC	_	PROPN	_	Number=Sing	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	antagonizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	transactivating	_	NOUN	_	Degree=Pos	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	classic	_	ADJ	_	Number=Sing	_	_	_	_
32	GCR	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	GCRbeta	_	PROPN	_	Number=Sing	_	_	_	_
6	could	_	AUX	_	VerbForm=Fin	_	_	_	_
7	account	_	VERB	_	VerbForm=Inf	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
10	insensitivity	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Bronchoalveolar	_	NOUN	_	Number=Sing	_	_	_	_
2	lavage	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	BAL	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
9	blood	_	NOUN	_	Number=Sing	_	_	_	_
10	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	GCRbeta	_	PROPN	_	Number=Sing	_	_	_	_
19	immunoreactivity	_	NOUN	_	Number=Sing	_	_	_	_
20	using	_	VERB	_	VerbForm=Ger	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	GCRbeta	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	antibody	_	NOUN	_	Number=Sing	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	immunohistochemical	_	ADJ	_	Degree=Pos	_	_	_	_
28	staining	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	localization	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	GCRbeta	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	using	_	VERB	_	VerbForm=Ger	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	double	_	ADJ	_	Degree=Pos	_	_	_	_
11	immunostaining	_	VERB	_	Degree=Pos	_	_	_	_
12	technique	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Patients	_	NOUN	_	Number=Plur	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	GC	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	insensitive	_	ADJ	_	Degree=Pos	_	_	_	_
6	asthma	_	NOUN	_	Number=Sing	_	_	_	_
7	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	significantly	_	ADV	_	_	_	_	_	_
10	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
11	number	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	GCRbeta	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	immunoreactive	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	BAL	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
22	blood	_	NOUN	_	Number=Sing	_	_	_	_
23	than	_	ADP	_	_	_	_	_	_
24	GC	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
27	asthmatics	_	NOUN	_	Number=Plur	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	normal	_	ADJ	_	Degree=Pos	_	_	_	_
30	control	_	NOUN	_	Number=Sing	_	_	_	_
31	subjects	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	GCRbeta	_	PROPN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	GC	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	insensitive	_	ADJ	_	Degree=Pos	_	_	_	_
9	asthma	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	particularly	_	ADV	_	_	_	_	_	_
12	high	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	airway	_	NOUN	_	Number=Sing	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	play	_	VERB	_	VerbForm=Inf	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	major	_	ADJ	_	Degree=Pos	_	_	_	_
25	role	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	asthma	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	GCRbeta	_	PROPN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	specimens	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	airways	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	patients	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	chronic	_	ADJ	_	Number=Sing	_	_	_	_
17	bronchitis	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	chronic	_	ADJ	_	Number=Sing	_	_	_	_
3	bronchitis	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	few	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	GCRbeta	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	positive	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	numbers	_	NOUN	_	Number=Plur	_	_	_	_
14	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	differ	_	VERB	_	VerbForm=Inf	_	_	_	_
17	significantly	_	ADV	_	_	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	normal	_	ADJ	_	Degree=Pos	_	_	_	_
20	control	_	NOUN	_	Number=Sing	_	_	_	_
21	subjects	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	GC	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	insensitive	_	ADJ	_	Degree=Pos	_	_	_	_
7	asthma	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	GCRbeta	_	PROPN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	airway	_	NOUN	_	Number=Sing	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003106	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tyrphostin	_	PROPN	_	Number=Sing	_	_	_	_
2	AG	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	490	_	NUM	_	NumType=Card	_	_	_	_
5	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
6	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	JAK3	_	PROPN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	STAT5a	_	PROPN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	b	_	NOUN	_	Number=Sing	_	_	_	_
14	signal	_	NOUN	_	Number=Sing	_	_	_	_
15	transduction	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	antigen	_	ADJ	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	activated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Janus	_	PROPN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	JAK3	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
10	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	development	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	utilize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	_	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	receptor	_	NOUN	_	Number=Sing	_	_	_	_
33	common	_	ADJ	_	Degree=Pos	_	_	_	_
34	gamma	_	NOUN	_	Number=Sing	_	_	_	_
35	chain	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	gamma	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	c	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Genetic	_	ADJ	_	Degree=Pos	_	_	_	_
2	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	JAK3	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	manifested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	severe	_	ADJ	_	Degree=Pos	_	_	_	_
9	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
11	disease	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	SCID	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	humans	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	mice	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	JAK3	_	PROPN	_	Number=Sing	_	_	_	_
7	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	pharmacological	_	ADJ	_	Degree=Pos	_	_	_	_
10	target	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	control	_	VERB	_	VerbForm=Inf	_	_	_	_
13	certain	_	ADJ	_	Degree=Pos	_	_	_	_
14	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	diseases	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	evidence	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	AG	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	490	_	NUM	_	NumType=Card	_	_	_	_
10	potently	_	ADV	_	_	_	_	_	_
11	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	autokinase	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	JAK3	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
19	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	DNA	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	signal	_	NOUN	_	Number=Sing	_	_	_	_
25	transducer	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	activator	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	5a	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	5b	_	NUM	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	STAT5a	_	NOUN	_	Number=Sing	_	_	_	_
35	/	_	PUNCT	_	_	_	_	_	_
36	b	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	other	_	ADJ	_	Degree=Pos	_	_	_	_
8	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	use	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	c	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	AG	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	490	_	NUM	_	NumType=Card	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	IC50	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	=	_	SYM	_	_	_	_	_	_
22	25	_	NUM	_	NumType=Card	_	_	_	_
23	microM	_	NOUN	_	Number=Sing	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	partially	_	ADV	_	_	_	_	_	_
27	recoverable	_	ADJ	_	Degree=Pos	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
8	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	tetanus	_	NOUN	_	Number=Sing	_	_	_	_
10	toxoid	_	NOUN	_	Number=Sing	_	_	_	_
11	antigen	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_

1	T	_	NUM	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	expansion	_	NOUN	_	Number=Sing	_	_	_	_
6	but	_	CCONJ	_	_	_	_	_	_
7	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	block	_	VERB	_	VerbForm=Inf	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Zap70	_	NOUN	_	Number=Sing	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	p56Lck	_	NOUN	_	Number=Sing	_	_	_	_
15	after	_	ADP	_	_	_	_	_	_
16	anti-CD3	_	ADJ	_	Degree=Pos	_	_	_	_
17	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	findings	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	AG	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	490	_	NUM	_	NumType=Card	_	_	_	_
11	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	JAK3	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	Type	_	NOUN	_	Number=Sing	_	_	_	_
17	II	_	NUM	_	NumType=Card	_	_	_	_
18	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
19	pathway	_	NOUN	_	Number=Sing	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	not	_	ADV	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	T	_	PROPN	_	Number=Sing	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	receptor	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	Type	_	NOUN	_	Number=Sing	_	_	_	_
29	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
30	pathway	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	possesses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
34	potential	_	NOUN	_	Number=Sing	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	T	_	PROPN	_	NumType=Card	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	pathologies	_	NOUN	_	Number=Plur	_	_	_	_
41	such	_	ADJ	_	Degree=Pos	_	_	_	_
42	as	_	ADP	_	_	_	_	_	_
43	graft	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	versus	_	ADP	_	_	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	host	_	NOUN	_	Number=Sing	_	_	_	_
48	disease	_	NOUN	_	Number=Sing	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	allergy	_	NOUN	_	Number=Sing	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	autoimmune	_	ADJ	_	Degree=Pos	_	_	_	_
54	disorders	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003107	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
9	matrix	_	NOUN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	tenascin	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Tenascin	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	TN	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	matrix	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	widely	_	ADV	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	fetus	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	sparingly	_	ADV	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	adult	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	reappears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	at	_	ADP	_	_	_	_	_	_
26	high	_	ADJ	_	Degree=Pos	_	_	_	_
27	levels	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	certain	_	ADJ	_	Degree=Pos	_	_	_	_
30	areas	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	tissue	_	NOUN	_	Degree=Pos	_	_	_	_
33	insult	_	NOUN	_	Number=Sing	_	_	_	_
34	such	_	ADJ	_	Degree=Pos	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	tumor	_	NOUN	_	Number=Sing	_	_	_	_
37	matrices	_	NOUN	_	Number=Plur	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	sites	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	wound	_	NOUN	_	Number=Sing	_	_	_	_
42	healing	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	soluble	_	ADJ	_	Number=Sing	_	_	_	_
6	TN	_	PROPN	_	Number=Sing	_	_	_	_
7	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	alpha	_	PROPN	_	Number=Sing	_	_	_	_
17	CD3	_	PROPN	_	Number=Sing	_	_	_	_

1	Ab	_	PROPN	_	Number=Sing	_	_	_	_
2	co-immobilized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
6	matrix	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	FN	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	TN	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
5	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	alpha	_	PROPN	_	Number=Sing	_	_	_	_
8	CD3	_	PROPN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
16	ester	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
24	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	high	_	ADJ	_	Degree=Pos	_	_	_	_
26	level	_	NOUN	_	Number=Sing	_	_	_	_
27	induction	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2R	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	presence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TN	_	PROPN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	culture	_	NOUN	_	Number=Sing	_	_	_	_
7	medium	_	NOUN	_	Number=Sing	_	_	_	_
8	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	detectably	_	ADV	_	_	_	_	_	_
11	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	pattern	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
16	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
17	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	triggering	_	VERB	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	alpha	_	PROPN	_	Number=Sing	_	_	_	_
24	CD3	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	at	_	ADP	_	_	_	_	_	_
28	later	_	ADV	_	Degree=Cmp	_	_	_	_
29	time	_	NOUN	_	Number=Sing	_	_	_	_
30	points	_	NOUN	_	Number=Plur	_	_	_	_
31	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	appearance	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	functional	_	ADJ	_	Degree=Pos	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	AT1	_	NOUN	_	Number=Sing	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	factor	_	NOUN	_	Number=Sing	_	_	_	_
41	complexes	_	NOUN	_	Number=Plur	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	T	_	PROPN	_	Number=Sing	_	_	_	_
44	cell	_	NOUN	_	Number=Sing	_	_	_	_
45	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
46	extracts	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	postulated	_	ADJ	_	Degree=Pos	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	TN	_	PROPN	_	Number=Sing	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	natural	_	ADJ	_	Degree=Pos	_	_	_	_
14	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	FN	_	PROPN	_	Number=Sing	_	_	_	_
17	action	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	suggest	_	VERB	_	VerbForm=Inf	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	T	_	DET	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	responses	_	NOUN	_	Number=Plur	_	_	_	_
25	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
26	at	_	ADP	_	_	_	_	_	_
27	tissue	_	NOUN	_	Number=Sing	_	_	_	_
28	sites	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	which	_	PRON	_	PronType=Rel	_	_	_	_
31	TN	_	PROPN	_	Number=Sing	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	could	_	AUX	_	VerbForm=Fin	_	_	_	_
35	be	_	AUX	_	VerbForm=Inf	_	_	_	_
36	influenced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
39	presence	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003108	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CBP	_	PROPN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	p300	_	PROPN	_	Number=Sing	_	_	_	_
4	integrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	Raf	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	Rac	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
10	pathways	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	ATc	_	NOUN	_	Number=Sing	_	_	_	_
19	during	_	ADP	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	ATc	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	inducibly	_	ADV	_	_	_	_	_	_
7	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	controls	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	T	_	ADJ	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	cardiomyocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	co-activators	_	NOUN	_	Number=Plur	_	_	_	_
8	CBP	_	PROPN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	p300	_	PROPN	_	Number=Sing	_	_	_	_
11	bind	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	control	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
20	N	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	terminal	_	NOUN	_	Number=Sing	_	_	_	_
23	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
24	domain	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	ATc	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	TAD	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	A.	_	PROPN	_	Number=Sing	_	_	_	_
33	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	N	_	PROPN	_	Number=Sing	_	_	_	_
37	terminal	_	PROPN	_	Number=Sing	_	_	_	_
38	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
39	domain	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	c	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	Jun	_	PROPN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	TAD	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	A	_	PROPN	_	Number=Sing	_	_	_	_
48	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	inducibly	_	ADV	_	_	_	_	_	_
50	phosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	but	_	CCONJ	_	_	_	_	_	_
53	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
54	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
55	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
56	dispensable	_	ADJ	_	Degree=Pos	_	_	_	_
57	for	_	ADP	_	_	_	_	_	_
58	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
59	interaction	_	NOUN	_	Number=Sing	_	_	_	_
60	with	_	ADP	_	_	_	_	_	_
61	CBP	_	NOUN	_	Number=Sing	_	_	_	_
62	/	_	PUNCT	_	_	_	_	_	_
63	p300	_	NOUN	_	Number=Sing	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	active	_	ADJ	_	Degree=Pos	_	_	_	_
3	versions	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	c-Raf	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	Rac	_	PROPN	_	Number=Sing	_	_	_	_
8	synergistically	_	ADV	_	_	_	_	_	_
9	enhance	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	CBP	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	p300	_	NUM	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
16	increase	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	TAD	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	important	_	ADJ	_	Degree=Pos	_	_	_	_
26	role	_	NOUN	_	Number=Sing	_	_	_	_
27	CBP	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	p300	_	NOUN	_	Number=Sing	_	_	_	_
30	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	integration	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	T	_	NOUN	_	Number=Sing	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	signals	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	mutation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	CBP	_	NOUN	_	Number=Sing	_	_	_	_
6	abolishing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	HAT	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	almost	_	ADV	_	_	_	_	_	_
11	as	_	ADV	_	_	_	_	_	_
12	active	_	ADJ	_	Degree=Pos	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	wild	_	ADJ	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	type	_	NOUN	_	Number=Sing	_	_	_	_
17	CBP	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	functions	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	CBP	_	NOUN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	p300	_	NOUN	_	Number=Sing	_	_	_	_
27	other	_	ADJ	_	Degree=Pos	_	_	_	_
28	than	_	ADP	_	_	_	_	_	_
29	histone	_	ADJ	_	Number=Sing	_	_	_	_
30	acetylation	_	NOUN	_	Number=Sing	_	_	_	_
31	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	control	_	VERB	_	VerbForm=Inf	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	AT	_	ADP	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
40	transcription	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	T	_	PROPN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003114	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Bik	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	death	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	shares	_	NOUN	_	Number=Plur	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
12	sequence	_	NOUN	_	Number=Sing	_	_	_	_
13	motif	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	family	_	NOUN	_	Number=Sing	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	interacts	_	VERB	_	Number=Plur	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	viral	_	ADJ	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
26	survival	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
29	proteins	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	survival	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	family	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	interactions	_	NOUN	_	Number=Plur	_	_	_	_
20	between	_	ADP	_	_	_	_	_	_
21	various	_	ADJ	_	Degree=Pos	_	_	_	_
22	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	novel	_	NOUN	_	Number=Sing	_	_	_	_
6	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	Bik	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
12	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
16	survival	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	xL	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	as	_	ADV	_	_	_	_	_	_
30	well	_	ADV	_	Degree=Pos	_	_	_	_
31	as	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	viral	_	ADJ	_	Degree=Pos	_	_	_	_
34	survival	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
37	proteins	_	NOUN	_	Number=Plur	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
40	Barr	_	PROPN	_	Number=Sing	_	_	_	_
41	virus	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	BHRF1	_	PROPN	_	Number=Sing	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	adenovirus	_	NOUN	_	Number=Sing	_	_	_	_
46	E1B	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	19	_	NUM	_	NumType=Card	_	_	_	_
49	kDa	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	transient	_	ADJ	_	Degree=Pos	_	_	_	_
3	transfection	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_

1	Bik	_	PROPN	_	Number=Sing	_	_	_	_
2	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	death	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	manner	_	NOUN	_	Number=Sing	_	_	_	_
8	similar	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	death	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
14	members	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	family	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	Bax	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	Bak	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	death	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Bik	_	PROPN	_	Number=Sing	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	coexpression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	XL	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	EBV	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	BHRF1	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	E1B	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	19	_	NUM	_	NumType=Card	_	_	_	_
29	kDa	_	PROPN	_	Number=Sing	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	that	_	SCONJ	_	_	_	_	_	_
33	Bik	_	PROPN	_	Number=Sing	_	_	_	_
34	may	_	AUX	_	VerbForm=Fin	_	_	_	_
35	be	_	AUX	_	VerbForm=Inf	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	common	_	ADJ	_	Degree=Pos	_	_	_	_
38	target	_	NOUN	_	Number=Sing	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	both	_	CCONJ	_	_	_	_	_	_
41	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	viral	_	ADJ	_	Degree=Pos	_	_	_	_
44	anti-apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
45	proteins	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	Bik	_	PROPN	_	Number=Sing	_	_	_	_
3	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	show	_	VERB	_	VerbForm=Inf	_	_	_	_
6	overt	_	ADP	_	Degree=Pos	_	_	_	_
7	homology	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	BH1	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	BH2	_	PROPN	_	Number=Sing	_	_	_	_
13	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	domains	_	NOUN	_	Number=Plur	_	_	_	_
15	characteristic	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	family	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
24	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	share	_	VERB	_	VerbForm=Inf	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	9	_	NUM	_	NumType=Card	_	_	_	_
28	amino	_	NOUN	_	Number=Sing	_	_	_	_
29	acid	_	NOUN	_	Number=Sing	_	_	_	_
30	domain	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	BH3	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	Bax	_	PROPN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	Bak	_	PROPN	_	Number=Sing	_	_	_	_
38	which	_	PRON	_	PronType=Rel	_	_	_	_
39	may	_	AUX	_	VerbForm=Fin	_	_	_	_
40	be	_	AUX	_	VerbForm=Inf	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	critical	_	ADJ	_	Degree=Pos	_	_	_	_
43	determinant	_	NOUN	_	Number=Sing	_	_	_	_
44	for	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	death	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
49	activity	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
52	proteins	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003117	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	type	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	stage	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	CD20	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	B1	_	PROPN	_	Number=Sing	_	_	_	_
14	antigen	_	NOUN	_	Number=Sing	_	_	_	_
15	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	diverged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	octamer	_	NOUN	_	Number=Sing	_	_	_	_
23	DNA	_	PROPN	_	Number=Sing	_	_	_	_
24	motif	_	NOUN	_	Number=Sing	_	_	_	_
25	present	_	ADJ	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CD20	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	B1	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	B	_	NUM	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	5	_	NUM	_	NumType=Card	_	_	_	_
4	'	_	PUNCT	_	_	_	_	_	_
5	deletion	_	NOUN	_	Number=Sing	_	_	_	_
6	CD20	_	NOUN	_	Number=Sing	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	CAT	_	NOUN	_	Number=Sing	_	_	_	_
10	constructs	_	NOUN	_	Number=Plur	_	_	_	_
11	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	previously	_	ADV	_	_	_	_	_	_
13	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	two	_	NUM	_	NumType=Card	_	_	_	_
15	regions	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	between	_	ADP	_	_	_	_	_	_
20	bases	_	NOUN	_	Number=Plur	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	186	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	-	_	SYM	_	_	_	_	_	_
25	280	_	NUM	_	NumType=Card	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	between	_	ADP	_	_	_	_	_	_
28	bases	_	NOUN	_	Number=Plur	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	280	_	NUM	_	NumType=Card	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	-	_	SYM	_	_	_	_	_	_
33	454	_	NUM	_	NumType=Card	_	_	_	_
34	which	_	PRON	_	PronType=Rel	_	_	_	_
35	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	positive	_	ADJ	_	Degree=Pos	_	_	_	_
37	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
38	elements	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	element	_	NOUN	_	Number=Sing	_	_	_	_
9	present	_	VERB	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	most	_	ADV	_	_	_	_	_	_
13	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
14	region	_	NOUN	_	Number=Sing	_	_	_	_
15	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	between	_	ADP	_	_	_	_	_	_
17	bases	_	NOUN	_	Number=Plur	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	214	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	-	_	SYM	_	_	_	_	_	_
22	201	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	TTCTTCTAATTAA	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	which	_	PRON	_	PronType=Rel	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	important	_	ADJ	_	Degree=Pos	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	high	_	ADJ	_	Degree=Pos	_	_	_	_
32	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	CD20	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	mature	_	ADJ	_	Degree=Pos	_	_	_	_
38	B	_	ADJ	_	Degree=Pos	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	induction	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	CD20	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	element	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	referred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	BAT	_	NOUN	_	Number=Sing	_	_	_	_
10	box	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	deletion	_	NOUN	_	Number=Sing	_	_	_	_
14	significantly	_	ADV	_	_	_	_	_	_
15	reduced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	CD20	_	NOUN	_	Number=Sing	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	CAT	_	NOUN	_	Number=Sing	_	_	_	_
24	construct	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	B	_	ADJ	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Mobility	_	NOUN	_	Number=Sing	_	_	_	_
2	shift	_	NOUN	_	Number=Sing	_	_	_	_
3	assays	_	VERB	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	various	_	ADJ	_	Degree=Pos	_	_	_	_
6	mutant	_	NOUN	_	Number=Sing	_	_	_	_
7	probes	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	B	_	ADJ	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	extracts	_	NOUN	_	Number=Plur	_	_	_	_
13	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	core	_	NOUN	_	Number=Sing	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	TAAT	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	essential	_	ADJ	_	Degree=Pos	_	_	_	_
21	for	_	SCONJ	_	_	_	_	_	_
22	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Cross	_	PROPN	_	Number=Sing	_	_	_	_
2	competition	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	octamer	_	NOUN	_	Number=Sing	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	Ig	_	PROPN	_	Number=Sing	_	_	_	_
11	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
12	chain	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	BAT	_	NOUN	_	Number=Sing	_	_	_	_
17	box	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	TA	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	rich	_	ADJ	_	Degree=Pos	_	_	_	_
24	sequence	_	NOUN	_	Number=Sing	_	_	_	_
25	present	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	CD21	_	PROPN	_	Number=Sing	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	all	_	DET	_	_	_	_	_	_
33	three	_	NUM	_	NumType=Card	_	_	_	_
34	sequences	_	NOUN	_	Number=Plur	_	_	_	_
35	bound	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	same	_	ADJ	_	Degree=Pos	_	_	_	_
38	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
39	proteins	_	NOUN	_	Number=Plur	_	_	_	_
40	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
41	that	_	SCONJ	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	BAT	_	NOUN	_	Number=Sing	_	_	_	_
44	box	_	NOUN	_	Number=Sing	_	_	_	_
45	binding	_	NOUN	_	Number=Sing	_	_	_	_
46	proteins	_	NOUN	_	Number=Plur	_	_	_	_
47	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
48	Oct	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	1	_	NUM	_	NumType=Card	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	Oct	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	2	_	NUM	_	NumType=Card	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Southwestern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blotting	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	UV	_	PROPN	_	Number=Sing	_	_	_	_
5	cross	_	VERB	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	linking	_	VERB	_	Number=Sing	_	_	_	_
8	studies	_	NOUN	_	Number=Plur	_	_	_	_
9	confirmed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	BAT	_	NOUN	_	Number=Sing	_	_	_	_
13	box	_	NOUN	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	Oct	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	Oct	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	affinity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	BAT	_	NOUN	_	Number=Sing	_	_	_	_
6	box	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	BAT	_	NOUN	_	Number=Sing	_	_	_	_
12	box	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	approximately	_	ADV	_	_	_	_	_	_
15	25	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
18	less	_	ADJ	_	Degree=Cmp	_	_	_	_
19	than	_	ADP	_	_	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	octamer	_	NOUN	_	Number=Sing	_	_	_	_
23	sequence	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	BAT	_	NOUN	_	Number=Sing	_	_	_	_
27	box	_	NOUN	_	Number=Sing	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	proteins	_	NOUN	_	Number=Plur	_	_	_	_
30	dissociated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	BAT	_	NOUN	_	Number=Sing	_	_	_	_
34	box	_	NOUN	_	Number=Sing	_	_	_	_
35	10	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	fold	_	VERB	_	Number=Sing	_	_	_	_
38	more	_	ADV	_	_	_	_	_	_
39	rapidly	_	ADV	_	_	_	_	_	_
40	than	_	ADP	_	_	_	_	_	_
41	from	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	octamer	_	NOUN	_	Number=Sing	_	_	_	_
44	sequence	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Despite	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
4	affinity	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	trimer	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	BAT	_	NOUN	_	Number=Sing	_	_	_	_
11	box	_	NOUN	_	Number=Sing	_	_	_	_
12	sequence	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	as	_	ADV	_	_	_	_	_	_
15	efficiently	_	ADV	_	_	_	_	_	_
16	transactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	Oct	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	vector	_	NOUN	_	Number=Sing	_	_	_	_
24	as	_	SCONJ	_	_	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	trimer	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	octamer	_	NOUN	_	Number=Sing	_	_	_	_
31	sequence	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	BAT	_	NOUN	_	Number=Sing	_	_	_	_
3	box	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Oct	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	CD20	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	line	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	PB	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	697	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	via	_	ADP	_	_	_	_	_	_
27	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
28	esters	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	CD20	_	PROPN	_	Number=Sing	_	_	_	_
5	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	temporally	_	ADV	_	_	_	_	_	_
8	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Oct	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	BAT	_	NOUN	_	Number=Sing	_	_	_	_
19	box	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	deleted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	CD20	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	CAT	_	NOUN	_	Number=Sing	_	_	_	_
25	construct	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	contrast	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	wild	_	NOUN	_	Number=Sing	_	_	_	_
32	type	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
35	poorly	_	ADV	_	_	_	_	_	_
36	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
39	esters	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	results	_	NOUN	_	Number=Plur	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	BAT	_	NOUN	_	Number=Sing	_	_	_	_
8	box	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	important	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	CD20	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	perhaps	_	ADV	_	_	_	_	_	_
23	CD21	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003118	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
2	acid	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CD38	_	PROPN	_	Number=Sing	_	_	_	_
8	antigen	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
16	acid	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	CD38	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	leukocyte	_	ADJ	_	Number=Sing	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	antigen	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
15	marker	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	different	_	ADJ	_	Degree=Pos	_	_	_	_
18	subpopulations	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	CD38	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	during	_	ADP	_	_	_	_	_	_
9	early	_	ADJ	_	Degree=Pos	_	_	_	_
10	stages	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Virtually	_	ADV	_	_	_	_	_	_
2	no	_	DET	_	_	_	_	_	_
3	information	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	available	_	ADJ	_	Degree=Pos	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	functions	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	CD38	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	all	_	DET	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	trans	_	NOUN	_	Number=Plur	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
10	acid	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	potent	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	highly	_	ADV	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	inducer	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	CD38	_	PROPN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
27	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	CD38	_	PROPN	_	Number=Sing	_	_	_	_
11	antigen	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	through	_	ADP	_	_	_	_	_	_
18	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
19	acid	_	ADJ	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	RAR	_	PROPN	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
2	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
5	CD38	_	PROPN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
10	subclone	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	HL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	60	_	NUM	_	NumType=Card	_	_	_	_
16	myeloid	_	NUM	_	NumType=Card	_	_	_	_
17	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	line	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	HL	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	60R	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	relatively	_	ADV	_	_	_	_	_	_
29	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
35	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Retroviral	_	ADJ	_	Degree=Pos	_	_	_	_
2	vector	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
5	transduction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	RA	_	PROPN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	RAR	_	PROPN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	into	_	ADP	_	_	_	_	_	_
14	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
15	HL	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	60	_	NUM	_	NumType=Card	_	_	_	_
18	R	_	PROPN	_	Number=Sing	_	_	_	_
19	subclone	_	NOUN	_	Number=Sing	_	_	_	_
20	completely	_	ADV	_	_	_	_	_	_
21	restored	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	terms	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
33	ability	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	express	_	VERB	_	VerbForm=Inf	_	_	_	_
36	CD38	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	CD38	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	HL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	60R	_	NUM	_	NumType=Card	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	functional	_	ADJ	_	Degree=Pos	_	_	_	_
21	RAR	_	NOUN	_	Number=Sing	_	_	_	_
22	beta	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	RAR	_	PROPN	_	Number=Sing	_	_	_	_
25	gamma	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	RXR	_	NOUN	_	Number=Sing	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	receptor	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CD38	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	acute	_	ADJ	_	Degree=Pos	_	_	_	_
6	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	acute	_	ADJ	_	Degree=Pos	_	_	_	_
9	myeloblastic	_	ADJ	_	Degree=Pos	_	_	_	_
10	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	independent	_	ADJ	_	Degree=Pos	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	cytodifferentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Following	_	VERB	_	VerbForm=Ger	_	_	_	_
2	culture	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	CD38	_	PROPN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	normal	_	ADJ	_	Degree=Pos	_	_	_	_
15	CD34	_	NOUN	_	Number=Sing	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_
17	bone	_	NOUN	_	NumType=Card	_	_	_	_
18	marrow	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	not	_	ADV	_	_	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	normal	_	ADJ	_	Degree=Pos	_	_	_	_
25	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
26	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	From	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	results	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	CD38	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
11	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
14	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	normal	_	ADJ	_	Degree=Pos	_	_	_	_
18	CD34	_	NOUN	_	Number=Sing	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	bone	_	NOUN	_	NumType=Card	_	_	_	_
21	marrow	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	independent	_	ADJ	_	Degree=Pos	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	RAR	_	PROPN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	HL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	60	_	NUM	_	NumType=Card	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	similar	_	ADJ	_	Degree=Pos	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	RAR	_	PROPN	_	Number=Sing	_	_	_	_
25	alpha	_	PROPN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	CD38	_	PROPN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	other	_	ADJ	_	Degree=Pos	_	_	_	_
31	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003119	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Altered	_	VERB	_	Degree=Pos	_	_	_	_
2	memory	_	NOUN	_	Number=Sing	_	_	_	_
3	T	_	NOUN	_	NumType=Card	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	patients	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	early	_	ADJ	_	Degree=Pos	_	_	_	_
10	rheumatoid	_	NOUN	_	Number=Sing	_	_	_	_
11	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
3	immune	_	NOUN	_	Degree=Pos	_	_	_	_
4	response	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	rheumatoid	_	ADJ	_	Number=Sing	_	_	_	_
7	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	RA	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	might	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	driven	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	without	_	ADP	_	_	_	_	_	_
19	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_

1	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	down	_	VERB	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	modulate	_	VERB	_	Degree=Pos	_	_	_	_
8	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	test	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	disordered	_	VERB	_	Degree=Pos	_	_	_	_
5	memory	_	NOUN	_	Number=Sing	_	_	_	_
6	T	_	NOUN	_	NumType=Card	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
9	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	typical	_	ADJ	_	Degree=Pos	_	_	_	_
13	Th1	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dominated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	chronic	_	ADJ	_	Number=Sing	_	_	_	_
17	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	RA	_	PROPN	_	Number=Sing	_	_	_	_
20	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
21	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	SCONJ	_	_	_	_	_	_
24	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	CD4	_	NOUN	_	Number=Sing	_	_	_	_
26	+	_	SYM	_	_	_	_	_	_
27	memory	_	NOUN	_	Number=Sing	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	patients	_	NOUN	_	Number=Sing	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	early	_	ADJ	_	Degree=Pos	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	6	_	NUM	_	NumType=Card	_	_	_	_
36	wk	_	NUM	_	NumType=Card	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	12	_	NUM	_	NumType=Card	_	_	_	_
39	mo	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
42	RA	_	NOUN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	age	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	sex	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	matched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
52	controls	_	NOUN	_	Number=Plur	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	vitro	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	difference	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	cytokine	_	ADJ	_	Number=Sing	_	_	_	_
5	secretion	_	NOUN	_	Number=Sing	_	_	_	_
6	profiles	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	freshly	_	ADV	_	_	_	_	_	_
9	isolated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
10	memory	_	NOUN	_	Number=Sing	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	between	_	ADP	_	_	_	_	_	_
16	patients	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	controls	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	culture	_	NOUN	_	Number=Sing	_	_	_	_
4	system	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	then	_	ADV	_	PronType=Dem	_	_	_	_
7	employed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	that	_	PRON	_	_	_	_	_	_
9	permitted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Th	_	NOUN	_	Number=Sing	_	_	_	_
14	effectors	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	SCONJ	_	_	_	_	_	_
16	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	memory	_	NOUN	_	Number=Sing	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	short	_	ADJ	_	Degree=Pos	_	_	_	_
22	term	_	NOUN	_	Number=Sing	_	_	_	_
23	priming	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	differences	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	priming	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	could	_	AUX	_	VerbForm=Fin	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	all	_	DET	_	_	_	_	_	_
8	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
9	controls	_	NOUN	_	Number=Plur	_	_	_	_
10	by	_	SCONJ	_	_	_	_	_	_
11	priming	_	VERB	_	VerbForm=Ger	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	anti-CD28	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	absence	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	TCR	_	NOUN	_	Number=Sing	_	_	_	_
19	ligation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	priming	_	VERB	_	VerbForm=Ger	_	_	_	_
5	under	_	ADP	_	_	_	_	_	_
6	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	conditions	_	NOUN	_	Number=Plur	_	_	_	_
8	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	only	_	ADV	_	_	_	_	_	_
14	9	_	NUM	_	NumType=Card	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	24	_	NUM	_	NumType=Card	_	_	_	_
17	RA	_	NOUN	_	Number=Sing	_	_	_	_
18	patients	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	4	_	NUM	_	NumType=Card	_	_	_	_
5	could	_	AUX	_	VerbForm=Fin	_	_	_	_
6	overcome	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
9	Th2	_	DET	_	Number=Sing	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	defect	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	seven	_	NUM	_	NumType=Card	_	_	_	_
14	patients	_	NOUN	_	Number=Plur	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	without	_	ADP	_	_	_	_	_	_
18	effect	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	remaining	_	ADJ	_	VerbForm=Ger	_	_	_	_
22	eight	_	NUM	_	NumType=Card	_	_	_	_
23	patients	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	all	_	DET	_	_	_	_	_	_
3	patients	_	NOUN	_	Number=Plur	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	decrease	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	significant	_	ADJ	_	Degree=Pos	_	_	_	_
17	increase	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	well	_	ADV	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	differentiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	IFN	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	gamma	_	NOUN	_	Number=Sing	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	not	_	ADV	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	evident	_	ADJ	_	Degree=Pos	_	_	_	_
36	after	_	SCONJ	_	_	_	_	_	_
37	priming	_	VERB	_	VerbForm=Ger	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	anti-CD28	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CD4	_	NOUN	_	Number=Sing	_	_	_	_
6	+	_	SYM	_	_	_	_	_	_
7	memory	_	NOUN	_	Number=Sing	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	patients	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	early	_	ADJ	_	Degree=Pos	_	_	_	_
14	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
15	RA	_	NOUN	_	Number=Sing	_	_	_	_
16	manifest	_	VERB	_	VerbForm=Inf	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	intrinsic	_	ADJ	_	Degree=Pos	_	_	_	_
19	abnormality	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	ability	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
25	into	_	ADP	_	_	_	_	_	_
26	specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
30	effector	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	that	_	PRON	_	PronType=Rel	_	_	_	_
33	might	_	AUX	_	VerbForm=Fin	_	_	_	_
34	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	characteristic	_	ADJ	_	Degree=Pos	_	_	_	_
38	Th1	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	dominated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	chronic	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	auto	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	immune	_	ADJ	_	Degree=Pos	_	_	_	_
46	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	RA	_	PROPN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003122	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	c-Myc	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	E1A	_	PROPN	_	Number=Sing	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
6	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	activated	_	VERB	_	VerbForm=Inf	_	_	_	_
9	NK	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
13	granules	_	NOUN	_	Number=Plur	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	death	_	NOUN	_	Number=Sing	_	_	_	_
16	effectors	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	contact	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	natural	_	ADJ	_	Degree=Pos	_	_	_	_
5	killer	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	NK	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	foreign	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	certain	_	ADJ	_	Degree=Pos	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	tumor	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	triggers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	cytolytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	machinery	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	NK	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	triggering	_	NOUN	_	Number=Sing	_	_	_	_
3	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	exocytosis	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
9	NK	_	PROPN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	granules	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	oncoproteins	_	NOUN	_	Degree=Pos	_	_	_	_
3	c-Myc	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	E1A	_	PROPN	_	Number=Sing	_	_	_	_
6	render	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	vulnerable	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	NK	_	PROPN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	cytolysis	_	NOUN	_	Number=Sing	_	_	_	_
14	yet	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	sensitization	_	NOUN	_	Number=Sing	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	well	_	ADV	_	Degree=Pos	_	_	_	_
22	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	model	_	NOUN	_	Number=Sing	_	_	_	_
4	where	_	ADV	_	PronType=Rel	_	_	_	_
5	foreign	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	rat	_	NOUN	_	Number=Sing	_	_	_	_
9	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	cocultured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	activated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
19	NK	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
23	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	NK	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	capable	_	ADJ	_	Degree=Pos	_	_	_	_
29	of	_	SCONJ	_	_	_	_	_	_
30	efficiently	_	ADV	_	_	_	_	_	_
31	killing	_	VERB	_	VerbForm=Ger	_	_	_	_
32	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
33	targets	_	NOUN	_	Number=Plur	_	_	_	_
34	only	_	ADV	_	_	_	_	_	_
35	if	_	SCONJ	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	overexpressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
41	c-Myc	_	NOUN	_	Number=Sing	_	_	_	_
42	or	_	CCONJ	_	_	_	_	_	_
43	E1A	_	PROPN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	parental	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
7	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
8	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
9	similarly	_	ADV	_	_	_	_	_	_
10	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	phosphoinositide	_	ADJ	_	Degree=Pos	_	_	_	_
12	hydrolysis	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	bound	_	ADJ	_	Degree=Pos	_	_	_	_
16	NK	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	NK	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	cytolytically	_	ADV	_	_	_	_	_	_
25	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	contact	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	both	_	DET	_	_	_	_	_	_
30	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
31	parental	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
34	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
35	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
36	target	_	NOUN	_	Number=Sing	_	_	_	_
37	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	death	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	independent	_	ADJ	_	Degree=Pos	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	wild	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	p53	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	anti-apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	EIB19K	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	provided	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	evidence	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	c-Myc	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	E1A	_	PROPN	_	Number=Sing	_	_	_	_
9	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	NK	_	PROPN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	cytolysis	_	NOUN	_	Number=Sing	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	post	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	triggering	_	ADJ	_	VerbForm=Ger	_	_	_	_
20	stage	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NK	_	PROPN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	target	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	interaction	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	consistence	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	c-Myc	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	E1A	_	PROPN	_	Number=Sing	_	_	_	_
8	overexpressing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	more	_	ADV	_	_	_	_	_	_
12	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cytolytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	effects	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	NK	_	PROPN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	granules	_	NOUN	_	Number=Plur	_	_	_	_
24	than	_	ADP	_	_	_	_	_	_
25	parental	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
6	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NK	_	PROPN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	granules	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	have	_	VERB	_	VerbForm=Inf	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	SCONJ	_	_	_	_	_	_
8	directing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cytolytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	action	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NK	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	towards	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	infected	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	cancer	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003125	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Lymphocyte	_	PROPN	_	Number=Sing	_	_	_	_
2	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_
5	predictor	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	sertraline	_	ADJ	_	Degree=Pos	_	_	_	_
8	response	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	adolescent	_	ADJ	_	Degree=Pos	_	_	_	_
11	major	_	ADJ	_	Degree=Pos	_	_	_	_
12	depressive	_	ADJ	_	Degree=Pos	_	_	_	_
13	disorder	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	MDD	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Major	_	ADJ	_	Degree=Pos	_	_	_	_
2	depressive	_	ADJ	_	Degree=Pos	_	_	_	_
3	disorder	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	MDD	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	adolescents	_	NOUN	_	Number=Plur	_	_	_	_
9	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	resistance	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	tricyclic	_	ADJ	_	Degree=Pos	_	_	_	_
13	antidepressants	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	absence	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	hypercortisolemia	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	efficacy	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	serotonin	_	NOUN	_	Number=Sing	_	_	_	_
5	reuptake	_	NOUN	_	Number=Sing	_	_	_	_
6	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	SRIs	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	uncertain	_	ADJ	_	Degree=Pos	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	predictors	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	unavailable	_	ADJ	_	Degree=Pos	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
2	fast	_	ADJ	_	Degree=Pos	_	_	_	_
3	feedback	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	negative	_	ADJ	_	Degree=Pos	_	_	_	_
6	feedback	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	hypothalamic	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	adrenal	_	ADJ	_	Degree=Pos	_	_	_	_
14	axis	_	NOUN	_	Number=Sing	_	_	_	_
15	implicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	dampened	_	VERB	_	Degree=Pos	_	_	_	_
18	limbic	_	NOUN	_	Degree=Pos	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	hippocampal	_	ADJ	_	Degree=Pos	_	_	_	_
21	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	II	_	NUM	_	NumType=Card	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	GCII	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	hypothesized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
5	GCII	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	adolescent	_	ADJ	_	Degree=Pos	_	_	_	_
10	MDD	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	could	_	AUX	_	VerbForm=Fin	_	_	_	_
13	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	marker	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	SRIs	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	open	_	ADJ	_	Degree=Pos	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	label	_	NOUN	_	Number=Sing	_	_	_	_
6	study	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	adolescents	_	NOUN	_	Number=Plur	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	n	_	NOUN	_	Number=Sing	_	_	_	_
11	=	_	PUNCT	_	_	_	_	_	_
12	20	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	meeting	_	NOUN	_	VerbForm=Ger	_	_	_	_
15	DSM	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	III	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	R	_	NOUN	_	Number=Sing	_	_	_	_
20	criteria	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	MDD	_	PROPN	_	Number=Sing	_	_	_	_
23	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	baseline	_	NOUN	_	Number=Sing	_	_	_	_
25	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
26	GCII	_	NOUN	_	Number=Sing	_	_	_	_
27	sites	_	NOUN	_	Number=Plur	_	_	_	_
28	per	_	ADP	_	_	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	sites	_	NOUN	_	Number=Plur	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	values	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	793	_	NUM	_	NumType=Card	_	_	_	_
38	+/-	_	SYM	_	_	_	_	_	_
39	106	_	NUM	_	NumType=Card	_	_	_	_
40	versus	_	ADP	_	_	_	_	_	_
41	2,563	_	NUM	_	NumType=Card	_	_	_	_
42	+/-	_	SYM	_	_	_	_	_	_
43	499	_	NUM	_	NumType=Card	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	+/-	_	SYM	_	_	_	_	_	_
46	SEM	_	NOUN	_	Number=Sing	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	for	_	ADP	_	_	_	_	_	_
49	matched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	controls	_	NOUN	_	Number=Plur	_	_	_	_
51	(	_	PUNCT	_	_	_	_	_	_
52	n	_	NOUN	_	Number=Sing	_	_	_	_
53	=	_	SYM	_	_	_	_	_	_
54	18	_	NUM	_	NumType=Card	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	(	_	PUNCT	_	_	_	_	_	_
57	t	_	NOUN	_	NumType=Card	_	_	_	_
58	=	_	SYM	_	_	_	_	_	_
59	3.5	_	NUM	_	NumType=Card	_	_	_	_
60	;	_	PUNCT	_	_	_	_	_	_
61	df	_	NOUN	_	Number=Sing	_	_	_	_
62	=	_	SYM	_	_	_	_	_	_
63	36	_	NUM	_	NumType=Card	_	_	_	_
64	;	_	PUNCT	_	_	_	_	_	_
65	p	_	NOUN	_	Number=Sing	_	_	_	_
66	<	_	PUNCT	_	_	_	_	_	_
67	.001	_	NUM	_	NumType=Card	_	_	_	_
68	)	_	PUNCT	_	_	_	_	_	_
69	.	_	PUNCT	_	_	_	_	_	_

1	GCII	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	bimodally	_	ADV	_	_	_	_	_	_
4	distributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	with	_	SCONJ	_	_	_	_	_	_
7	SRI	_	PROPN	_	Number=Sing	_	_	_	_
8	responders	_	NOUN	_	Number=Plur	_	_	_	_
9	differing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	nonresponders	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	t	_	NOUN	_	Number=Sing	_	_	_	_
14	=	_	SYM	_	_	_	_	_	_
15	3.9	_	NUM	_	NumType=Card	_	_	_	_
16	;	_	PUNCT	_	_	_	_	_	_
17	df	_	PROPN	_	Number=Sing	_	_	_	_
18	=	_	SYM	_	_	_	_	_	_
19	14	_	NUM	_	NumType=Card	_	_	_	_
20	;	_	PUNCT	_	_	_	_	_	_
21	p	_	NOUN	_	Number=Sing	_	_	_	_
22	<	_	PUNCT	_	_	_	_	_	_
23	.001	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	GCII	_	PROPN	_	Number=Sing	_	_	_	_
2	accurately	_	ADV	_	_	_	_	_	_
3	classified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	90	_	NUM	_	NumType=Card	_	_	_	_
5	percent	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	sertraline	_	NOUN	_	Number=Sing	_	_	_	_
8	responders	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	80	_	NUM	_	NumType=Card	_	_	_	_
11	percent	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	nonresponders	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Only	_	ADV	_	_	_	_	_	_
2	SRI	_	PROPN	_	Number=Sing	_	_	_	_
3	responders	_	NOUN	_	Number=Plur	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	GCII	_	NOUN	_	Number=Sing	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	upregulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	after	_	ADP	_	_	_	_	_	_
11	6	_	NUM	_	NumType=Card	_	_	_	_
12	weeks	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	treatment	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	t	_	NOUN	_	Number=Sing	_	_	_	_
17	=	_	SYM	_	_	_	_	_	_
18	2.1	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	df	_	NOUN	_	Number=Sing	_	_	_	_
21	=	_	SYM	_	_	_	_	_	_
22	10	_	NUM	_	NumType=Card	_	_	_	_
23	;	_	PUNCT	_	_	_	_	_	_
24	p	_	NOUN	_	Number=Sing	_	_	_	_
25	<	_	PUNCT	_	_	_	_	_	_
26	.05	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003126	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	core	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	AML1	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	subunits	_	NOUN	_	Number=Plur	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	murine	_	ADJ	_	Number=Sing	_	_	_	_
17	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
20	cores	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Core	_	NOUN	_	Number=Sing	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	CBF	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	polyomavirus	_	PROPN	_	Number=Sing	_	_	_	_
12	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	binding	_	VERB	_	Number=Sing	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	SL3	_	NOUN	_	Number=Sing	_	_	_	_
19	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	element	_	NOUN	_	Number=Sing	_	_	_	_
33	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	core	_	NOUN	_	Number=Sing	_	_	_	_
36	within	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	murine	_	NOUN	_	Number=Sing	_	_	_	_
42	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
43	virus	_	NOUN	_	Number=Sing	_	_	_	_
44	family	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	retroviruses	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	core	_	NOUN	_	Number=Sing	_	_	_	_
3	elements	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	SL3	_	NOUN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
11	determinants	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	ability	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
20	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
21	lymphomas	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	viral	_	ADJ	_	Degree=Pos	_	_	_	_
29	long	_	ADJ	_	Degree=Pos	_	_	_	_
30	terminal	_	NOUN	_	Number=Sing	_	_	_	_
31	repeat	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	T	_	PROPN	_	Number=Sing	_	_	_	_
34	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	CBF	_	NOUN	_	Number=Sing	_	_	_	_
2	consists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	subunits	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	DNA	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	subunit	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	CBF	_	PROPN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
18	subunit	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	CBF	_	PROPN	_	Number=Sing	_	_	_	_
21	beta	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	DNA	_	PROPN	_	Number=Sing	_	_	_	_
27	binding	_	VERB	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	CBF	_	PROPN	_	Number=Sing	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	genes	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	CBF	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	subunit	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	AML1	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	Cbf	_	PROPN	_	Number=Sing	_	_	_	_
17	alpha	_	PROPN	_	Number=Sing	_	_	_	_

1	2	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	locus	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	rearranged	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
7	translocations	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	myeloproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
11	disorders	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	leukemias	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	exogenously	_	ADV	_	_	_	_	_	_
3	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	Cbf	_	PROPN	_	Number=Sing	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	subunit	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	CBF	_	PROPN	_	Number=Sing	_	_	_	_
12	alpha	_	PROPN	_	Number=Sing	_	_	_	_
13	2-451	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	SL3	_	NOUN	_	Number=Sing	_	_	_	_
20	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	P19	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Activity	_	NOUN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	through	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	core	_	NOUN	_	Number=Sing	_	_	_	_
7	elements	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Three	_	NUM	_	NumType=Card	_	_	_	_
2	different	_	ADJ	_	Degree=Pos	_	_	_	_
3	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	CBF	_	PROPN	_	Number=Sing	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	tested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	SL3	_	NOUN	_	Number=Sing	_	_	_	_
16	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	longest	_	ADJ	_	Degree=Sup	_	_	_	_
3	form	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	CBF	_	PROPN	_	Number=Sing	_	_	_	_
6	beta-187	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	CBF	_	PROPN	_	Number=Sing	_	_	_	_
14	alpha	_	PROPN	_	Number=Sing	_	_	_	_
15	2-451	_	NUM	_	NumType=Card	_	_	_	_
16	twofold	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	although	_	SCONJ	_	_	_	_	_	_
22	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
23	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	no	_	DET	_	_	_	_	_	_
25	effect	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	P19	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	CBF	_	PROPN	_	Number=Sing	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	CBF	_	PROPN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	subunit	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	form	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	CBF	_	NOUN	_	Number=Sing	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	lacked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	ability	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	CBF	_	PROPN	_	Number=Sing	_	_	_	_
26	beta-148	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
31	activity	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	at	_	ADV	_	_	_	_	_	_
6	least	_	ADV	_	Degree=Sup	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	certain	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	types	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	maximum	_	ADJ	_	Degree=Pos	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	CBF	_	NOUN	_	Number=Sing	_	_	_	_
17	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	subunits	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	provided	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	support	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	CBF	_	PROPN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	recognition	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	SL3	_	NOUN	_	Number=Sing	_	_	_	_
24	cores	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	whether	_	SCONJ	_	_	_	_	_	_
5	CBF	_	PROPN	_	Number=Sing	_	_	_	_
6	could	_	AUX	_	VerbForm=Fin	_	_	_	_
7	distinguish	_	VERB	_	VerbForm=Inf	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	bp	_	NOUN	_	Number=Sing	_	_	_	_
12	difference	_	NOUN	_	Number=Sing	_	_	_	_
13	between	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	core	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	SL3	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	core	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	nonleukemogenic	_	ADJ	_	Degree=Pos	_	_	_	_
25	virus	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	Akv	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	difference	_	NOUN	_	Number=Sing	_	_	_	_
3	strongly	_	ADV	_	_	_	_	_	_
4	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	leukemogenicity	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	SL3	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	combination	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CBF	_	PROPN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	CBF	_	PROPN	_	Number=Sing	_	_	_	_
10	beta	_	NOUN	_	Number=Sing	_	_	_	_
11	subunits	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	able	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	distinguish	_	VERB	_	VerbForm=Inf	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	bp	_	NOUN	_	Number=Sing	_	_	_	_
23	difference	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	assays	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	complete	_	ADJ	_	Degree=Pos	_	_	_	_
5	understanding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	SCONJ	_	_	_	_	_	_
7	how	_	ADV	_	PronType=Int	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	recognize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	SL3	_	NOUN	_	Number=Sing	_	_	_	_
13	core	_	NOUN	_	Number=Sing	_	_	_	_
14	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	elucidated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003129	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Selective	_	ADJ	_	Degree=Pos	_	_	_	_
2	DNA	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	STAT	_	NOUN	_	Number=Sing	_	_	_	_
13	molecules	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	interferon	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	IFN	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	gamma	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	10	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	10	_	NUM	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	various	_	ADJ	_	Degree=Pos	_	_	_	_
25	reverse	_	NOUN	_	Number=Sing	_	_	_	_
26	effects	_	NOUN	_	Number=Plur	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
29	;	_	PUNCT	_	_	_	_	_	_
30	however	_	ADV	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
34	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
37	difference	_	NOUN	_	Number=Sing	_	_	_	_
38	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	not	_	PART	_	_	_	_	_	_
40	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
41	fully	_	ADV	_	_	_	_	_	_
42	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	10	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IFN	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	gamma	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	STAT	_	NOUN	_	Number=Sing	_	_	_	_
22	molecules	_	NOUN	_	Number=Plur	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	two	_	NUM	_	NumType=Card	_	_	_	_
25	kinds	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	GAS	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	motif	_	NOUN	_	Number=Sing	_	_	_	_
30	sequences	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
7	could	_	AUX	_	VerbForm=Fin	_	_	_	_
8	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	GAS	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	motif	_	NOUN	_	Number=Sing	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	promoter	_	ADJ	_	Number=Sing	_	_	_	_
18	region	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	Fcgamma	_	PROPN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	not	_	ADV	_	_	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	promoter	_	ADJ	_	Number=Sing	_	_	_	_
31	region	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	COX	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	gene	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	whereas	_	SCONJ	_	_	_	_	_	_
40	IFN	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	gamma	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
48	could	_	AUX	_	VerbForm=Fin	_	_	_	_
49	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	both	_	DET	_	_	_	_	_	_
52	sequences	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	STAT	_	PROPN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	without	_	ADP	_	_	_	_	_	_
13	newly	_	ADV	_	_	_	_	_	_
14	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	but	_	CCONJ	_	_	_	_	_	_
8	not	_	ADV	_	_	_	_	_	_
9	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	IFN	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	gamma	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	STAT	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
14	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	specificity	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	SCONJ	_	_	_	_	_	_
18	binding	_	VERB	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	GAS	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	motif	_	NOUN	_	Number=Sing	_	_	_	_
24	sequences	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	whereas	_	SCONJ	_	_	_	_	_	_
27	IFN	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	gamma	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
35	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	broader	_	ADJ	_	Degree=Cmp	_	_	_	_
38	spectrum	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	binding	_	VERB	_	Number=Sing	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	GAS	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	motif	_	NOUN	_	Number=Sing	_	_	_	_
46	sequences	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	difference	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	IFN	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	biological	_	ADJ	_	Degree=Pos	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
21	effect	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	10	_	NUM	_	NumType=Card	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	IFN	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	gamma	_	NOUN	_	Number=Sing	_	_	_	_
30	activities	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003130	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
4	H	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	7	_	NUM	_	NumType=Card	_	_	_	_
7	blocks	_	NOUN	_	Number=Plur	_	_	_	_
8	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	unspliced	_	ADJ	_	Degree=Pos	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
15	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Rex	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	post-transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulator	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
9	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	type	_	NOUN	_	Number=Sing	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
23	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	unspliced	_	ADJ	_	Degree=Pos	_	_	_	_
27	viral	_	ADJ	_	Degree=Pos	_	_	_	_
28	gag	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	pol	_	NOUN	_	Number=Sing	_	_	_	_
31	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Rex	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	phosphoprotein	_	NOUN	_	Number=Sing	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	nucleolus	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
12	function	_	NOUN	_	Number=Sing	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	localization	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	Rex	_	NOUN	_	Number=Sing	_	_	_	_
10	function	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	SCONJ	_	_	_	_	_	_
12	using	_	VERB	_	VerbForm=Ger	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	H	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	7	_	NUM	_	NumType=Card	_	_	_	_
21	[	_	PUNCT	_	_	_	_	_	_
22	1-(5-isoquinolinyl-sulfonyl)-2-methylpiperazine	_	NOUN	_	NumType=Card	_	_	_	_
23	]	_	PUNCT	_	_	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	infected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	H	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	7	_	NUM	_	NumType=Card	_	_	_	_
15	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	specifically	_	ADV	_	_	_	_	_	_
17	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	unspliced	_	ADJ	_	Degree=Pos	_	_	_	_
21	gag	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	pol	_	NOUN	_	Number=Sing	_	_	_	_
24	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	Gag	_	NOUN	_	Number=Sing	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
33	that	_	PRON	_	PronType=Rel	_	_	_	_
34	corresponds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	vivo	_	NOUN	_	Number=Sing	_	_	_	_
40	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	Rex	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	other	_	ADJ	_	Degree=Pos	_	_	_	_
5	viral	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	products	_	NOUN	_	Number=Plur	_	_	_	_
9	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	influenced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	H	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	SYM	_	_	_	_	_	_
19	7	_	NUM	_	NumType=Card	_	_	_	_
20	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Rex	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	viral	_	ADJ	_	Degree=Pos	_	_	_	_
12	RNA	_	PROPN	_	Number=Sing	_	_	_	_
13	partition	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003133	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	G	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	Anh	_	PROPN	_	_	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	MTetra	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	natural	_	ADJ	_	Degree=Pos	_	_	_	_
9	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	wall	_	NOUN	_	Number=Sing	_	_	_	_
12	breakdown	_	NOUN	_	Number=Sing	_	_	_	_
13	product	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	6	_	NUM	_	NumType=Card	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
7	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	[	_	PUNCT	_	_	_	_	_	_
13	published	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	erratum	_	NOUN	_	Number=Sing	_	_	_	_
15	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	J	_	PROPN	_	Number=Sing	_	_	_	_
18	Biol	_	PROPN	_	Number=Sing	_	_	_	_
19	Chem	_	PROPN	_	Number=Sing	_	_	_	_
20	1994	_	NUM	_	NumType=Card	_	_	_	_
21	Jun	_	PROPN	_	Number=Sing	_	_	_	_
22	17;269	_	NUM	_	NumType=Card	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	24	_	NUM	_	NumType=Card	_	_	_	_
25	):16983	_	PUNCT	_	_	_	_	_	_
26	]	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	wall	_	NOUN	_	Number=Sing	_	_	_	_
13	components	_	NOUN	_	Number=Plur	_	_	_	_
14	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	role	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	development	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	course	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	most	_	ADJ	_	Degree=Sup	_	_	_	_
4	attention	_	NOUN	_	Number=Sing	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	focused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	LPS	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	ability	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	N-acetylglucosaminyl	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1,6-	_	NUM	_	_	_	_	_	_
9	anhydro-N-acetylmuramyl	_	NOUN	_	Number=Sing	_	_	_	_
10	-L	_	PUNCT	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alanyl-D	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	isoglutamyl-m-diaminopimelyl-D-alanine	_	NOUN	_	Number=Sing	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	G	_	PROPN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	Anh	_	PROPN	_	_	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	MTetra	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	naturally	_	ADV	_	_	_	_	_	_
11	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
12	breakdown	_	NOUN	_	Number=Sing	_	_	_	_
13	product	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	peptidoglycan	_	NOUN	_	Number=Sing	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
21	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	transglycosylase	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	Escherichia	_	PROPN	_	Number=Sing	_	_	_	_
25	coli	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
29	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	human	_	ADJ	_	Degree=Pos	_	_	_	_
33	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	G	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	Anh	_	X	_	_	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	MTetra	_	PROPN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	strongly	_	ADV	_	_	_	_	_	_
10	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
11	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	beta	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	6	_	NUM	_	NumType=Card	_	_	_	_
22	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	after	_	ADP	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	h	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	beta	_	PROPN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	6	_	NUM	_	NumType=Card	_	_	_	_
36	protein	_	NOUN	_	Number=Sing	_	_	_	_
37	secretion	_	NOUN	_	Number=Sing	_	_	_	_
38	after	_	ADP	_	_	_	_	_	_
39	48	_	NUM	_	NumType=Card	_	_	_	_
40	h	_	NOUN	_	Number=Plur	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	activation	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	increase	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
5	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	at	_	ADV	_	_	_	_	_	_
8	least	_	ADV	_	Degree=Sup	_	_	_	_
9	partly	_	ADV	_	_	_	_	_	_
10	due	_	ADP	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	increase	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	rates	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	respective	_	ADJ	_	Degree=Pos	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	strong	_	ADJ	_	Degree=Pos	_	_	_	_
28	induction	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	activator	_	NOUN	_	Number=Sing	_	_	_	_
37	protein	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	transcription	_	NOUN	_	Number=Sing	_	_	_	_
41	factor	_	NOUN	_	Number=Sing	_	_	_	_
42	expression	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Experiments	_	NOUN	_	Number=Plur	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	C	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	kinase	_	NOUN	_	Number=Sing	_	_	_	_
11	A	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	pathways	_	NOUN	_	Number=Plur	_	_	_	_
19	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	G	_	PROPN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	Anh	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	MTetra	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	beta	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	6	_	NUM	_	NumType=Card	_	_	_	_
36	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
37	expression	_	NOUN	_	Number=Sing	_	_	_	_
38	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	H7	_	NUM	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	inhibitable	_	ADJ	_	Degree=Pos	_	_	_	_
45	pathway	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
6	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
7	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	G	_	PROPN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	Anh	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	MTetra	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	6	_	NUM	_	NumType=Card	_	_	_	_
23	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	new	_	ADJ	_	Degree=Pos	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	whereas	_	SCONJ	_	_	_	_	_	_
34	G	_	PROPN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	Anh	_	PROPN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	MTetra	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	1	_	NUM	_	NumType=Card	_	_	_	_
44	beta	_	NOUN	_	Number=Sing	_	_	_	_
45	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
46	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
47	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
48	not	_	PART	_	_	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	responses	_	NOUN	_	Number=Plur	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	G	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	Anh	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	MTetra	_	PROPN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	LPS	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	muramyldipeptide	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	MDP	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
27	response	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	G	_	PROPN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	Anh	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	MTetra	_	PROPN	_	Number=Sing	_	_	_	_
34	induction	_	NOUN	_	Number=Sing	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	similar	_	ADJ	_	Degree=Pos	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	LPS	_	NOUN	_	Number=Sing	_	_	_	_
41	but	_	CCONJ	_	_	_	_	_	_
42	significantly	_	ADV	_	_	_	_	_	_
43	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
44	than	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	response	_	NOUN	_	Number=Sing	_	_	_	_
47	to	_	ADP	_	_	_	_	_	_
48	MDP	_	PROPN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	maximal	_	PROPN	_	Number=Sing	_	_	_	_
4	G	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	Anh	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	MTetra	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	beta	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	6	_	NUM	_	NumType=Card	_	_	_	_
19	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	could	_	AUX	_	VerbForm=Fin	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	co-stimulation	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	LPS	_	NOUN	_	Number=Plur	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	MDP	_	PROPN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	that	_	SCONJ	_	_	_	_	_	_
33	different	_	ADJ	_	Degree=Pos	_	_	_	_
34	receptors	_	NOUN	_	Number=Plur	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	transduction	_	NOUN	_	Number=Sing	_	_	_	_
39	pathways	_	NOUN	_	Number=Plur	_	_	_	_
40	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	involved	_	ADJ	_	Degree=Pos	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	G	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	Anh	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	MTetra	_	PROPN	_	Number=Sing	_	_	_	_
10	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	beta	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	6	_	NUM	_	NumType=Card	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	possible	_	ADJ	_	Degree=Pos	_	_	_	_
26	role	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	G	_	PROPN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	Anh	_	PROPN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	MTetra	_	PROPN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	release	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
38	during	_	ADP	_	_	_	_	_	_
39	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003134	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
2	beta	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	rheumatoid	_	ADJ	_	Number=Sing	_	_	_	_
5	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
6	:	_	PUNCT	_	_	_	_	_	_
7	correlation	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	not	_	ADV	_	_	_	_	_	_
12	disease	_	NOUN	_	Number=Sing	_	_	_	_
13	specificity	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Rheumatoid	_	PROPN	_	Number=Sing	_	_	_	_
2	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
3	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
4	tissue	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	osteoarthritis	_	NOUN	_	Number=Sing	_	_	_	_
11	tissue	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	presence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
21	beta	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	6	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	lining	_	NOUN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	sublining	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	subcellular	_	ADJ	_	Degree=Pos	_	_	_	_
14	distribution	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
25	beta	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Rheumatoid	_	PROPN	_	Number=Sing	_	_	_	_
2	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
3	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
4	fluid	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	normal	_	ADJ	_	Degree=Pos	_	_	_	_
9	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
10	blood	_	NOUN	_	Number=Sing	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
2	beta	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
8	lining	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	sublining	_	ADJ	_	VerbForm=Ger	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
15	tissue	_	NOUN	_	Number=Sing	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	patients	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	rheumatoid	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	osteoarthritis	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	significant	_	ADJ	_	Degree=Pos	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	P	_	NOUN	_	Number=Sing	_	_	_	_
5	<	_	PUNCT	_	_	_	_	_	_
6	0.001	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	<	_	PUNCT	_	_	_	_	_	_
9	0.05	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	respectively	_	ADV	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	increase	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	percentage	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	staining	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	lining	_	VERB	_	Number=Sing	_	_	_	_
27	layer	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	sublining	_	NOUN	_	Number=Sing	_	_	_	_
35	region	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	rheumatoid	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	osteoarthritis	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	both	_	DET	_	_	_	_	_	_
3	diseases	_	NOUN	_	Number=Plur	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	strong	_	ADJ	_	Degree=Pos	_	_	_	_
6	correlation	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	r	_	NOUN	_	Number=Sing	_	_	_	_
9	=	_	SYM	_	_	_	_	_	_
10	0.79	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	P	_	NOUN	_	Number=Sing	_	_	_	_
13	<	_	PUNCT	_	_	_	_	_	_
14	0.001	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	between	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	percentage	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
26	lining	_	NOUN	_	Number=Sing	_	_	_	_
27	that	_	PRON	_	PronType=Rel	_	_	_	_
28	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	positive	_	ADJ	_	Degree=Pos	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
32	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
33	beta	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	lining	_	NOUN	_	Number=Sing	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	depth	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	color	_	NOUN	_	Number=Sing	_	_	_	_
4	immunohistochemistry	_	NOUN	_	Number=Sing	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	both	_	DET	_	_	_	_	_	_
8	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	fibroblast	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	like	_	ADJ	_	Degree=Pos	_	_	_	_
13	synoviocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	positive	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	presence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	immunohistochemistry	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	Western	_	ADJ	_	Degree=Pos	_	_	_	_
12	blot	_	NOUN	_	Number=Sing	_	_	_	_
13	analysis	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
17	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
3	beta	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	rheumatoid	_	ADJ	_	Degree=Pos	_	_	_	_
9	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
10	fluid	_	NOUN	_	Number=Sing	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	confirmed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	presence	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
9	beta	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	intensity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	staining	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	P	_	NOUN	_	Number=Sing	_	_	_	_
11	<	_	PUNCT	_	_	_	_	_	_
12	0.001	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
16	fluid	_	ADJ	_	Number=Sing	_	_	_	_
17	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	normal	_	ADJ	_	Degree=Pos	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	rheumatoid	_	ADJ	_	Degree=Pos	_	_	_	_
25	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
26	blood	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	staining	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
10	beta	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
14	lining	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	sublining	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	lining	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	positive	_	ADJ	_	Degree=Pos	_	_	_	_
30	correlation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	lining	_	VERB	_	VerbForm=Ger	_	_	_	_
33	layer	_	NOUN	_	Number=Sing	_	_	_	_
34	depth	_	NOUN	_	Number=Sing	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	percentage	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	lining	_	NOUN	_	Number=Sing	_	_	_	_
43	positive	_	ADJ	_	Number=Sing	_	_	_	_
44	for	_	ADP	_	_	_	_	_	_
45	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
46	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
47	beta	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	suggest	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
50	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
51	potential	_	ADJ	_	Degree=Pos	_	_	_	_
52	role	_	NOUN	_	Number=Sing	_	_	_	_
53	for	_	ADP	_	_	_	_	_	_
54	C	_	NOUN	_	Number=Sing	_	_	_	_
55	/	_	PUNCT	_	_	_	_	_	_
56	EBP	_	PROPN	_	Number=Sing	_	_	_	_
57	beta	_	NOUN	_	Number=Sing	_	_	_	_
58	in	_	ADP	_	_	_	_	_	_
59	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
60	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	production	_	NOUN	_	Number=Sing	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
10	beta	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
14	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	mediator	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
19	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	offers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	novel	_	NOUN	_	Number=Sing	_	_	_	_
26	approach	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
29	intervention	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003138	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	Jak	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	STAT	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	signaling	_	NOUN	_	Number=Sing	_	_	_	_
10	pathway	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	5	_	NUM	_	NumType=Card	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	signal	_	NOUN	_	Number=Sing	_	_	_	_
4	transduction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	objective	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	involvement	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	newly	_	ADV	_	_	_	_	_	_
14	discovered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	Jak	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	STAT	_	PROPN	_	Number=Sing	_	_	_	_
18	pathway	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	5	_	NUM	_	NumType=Card	_	_	_	_
24	signal	_	NOUN	_	Number=Sing	_	_	_	_
25	transduction	_	NOUN	_	Number=Sing	_	_	_	_
26	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	purified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	discontinuous	_	ADJ	_	Degree=Pos	_	_	_	_
9	Percoll	_	NOUN	_	Number=Sing	_	_	_	_
10	gradients	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	5	_	NUM	_	NumType=Card	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	involvement	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Jak	_	PROPN	_	Number=Sing	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
10	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	immunoblotting	_	VERB	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
15	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Jak	_	PROPN	_	Number=Sing	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	autophosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	immunoprecipitated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Jak	_	PROPN	_	Number=Sing	_	_	_	_
2	2	_	NUM	_	NumType=Card	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	within	_	ADP	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	min	_	NOUN	_	Number=Plur	_	_	_	_
11	after	_	ADP	_	_	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	5.	_	NUM	_	NumType=Card	_	_	_	_
19	Further	_	ADV	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	immunoprecipitated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	Jak	_	PROPN	_	Number=Sing	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	5	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	underwent	_	VERB	_	Degree=Pos	_	_	_	_
34	autophosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Jak	_	PROPN	_	Number=Sing	_	_	_	_
2	2	_	NUM	_	NumType=Card	_	_	_	_
3	coprecipitated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	subunit	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	5	_	NUM	_	NumType=Card	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	physical	_	ADJ	_	Degree=Pos	_	_	_	_
19	association	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	kinase	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	receptor	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	STAT	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	p91	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
14	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	immunoblotting	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
19	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	STAT	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
6	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	within	_	ADP	_	_	_	_	_	_
8	15	_	NUM	_	NumType=Card	_	_	_	_
9	min	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	SYM	_	_	_	_	_	_
13	5	_	NUM	_	NumType=Card	_	_	_	_
14	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	presence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	STAT	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	extract	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
15	mobility	_	NOUN	_	Number=Sing	_	_	_	_
16	shift	_	NOUN	_	Number=Sing	_	_	_	_
17	assay	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	5	_	NUM	_	NumType=Card	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	proteins	_	NOUN	_	Number=Plur	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	bound	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	activating	_	NOUN	_	Number=Sing	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	presence	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	anti-STAT	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	Ab	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	band	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	supershifted	_	ADJ	_	Degree=Pos	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	Jak	_	PROPN	_	Number=Sing	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	STAT	_	NOUN	_	Number=Sing	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	signaling	_	NOUN	_	Number=Sing	_	_	_	_
17	pathway	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	speculate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	Jak	_	PROPN	_	Number=Sing	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	STAT	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	pathway	_	NOUN	_	Number=Sing	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	involved	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	5	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003139	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Retinoid	_	PROPN	_	Number=Sing	_	_	_	_
2	X	_	PROPN	_	_	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	RXR	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	agonist	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	negative	_	ADJ	_	Degree=Pos	_	_	_	_
15	RXR	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
18	acid	_	NOUN	_	Number=Sing	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	alpha403	_	NOUN	_	Number=Sing	_	_	_	_
21	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	developmentally	_	ADV	_	_	_	_	_	_
24	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	during	_	ADP	_	_	_	_	_	_
26	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
27	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
3	biologic	_	NOUN	_	Number=Sing	_	_	_	_
4	activities	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	retinoic	_	ADJ	_	Number=Sing	_	_	_	_
7	acid	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	RA	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	through	_	ADP	_	_	_	_	_	_
14	RAR	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	retinoid	_	VERB	_	Number=Sing	_	_	_	_
17	X	_	PROPN	_	_	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	RXR	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	receptors	_	NOUN	_	Number=Plur	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	DNA	_	NOUN	_	Number=Sing	_	_	_	_
29	target	_	NOUN	_	Number=Sing	_	_	_	_
30	sequences	_	NOUN	_	Number=Plur	_	_	_	_
31	as	_	ADP	_	_	_	_	_	_
32	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	RXR	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	RAR	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	RXR	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	RXR	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	RA	_	PROPN	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	critical	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	SCONJ	_	_	_	_	_	_
7	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	important	_	ADJ	_	Degree=Pos	_	_	_	_
9	aspects	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	since	_	SCONJ	_	_	_	_	_	_
14	transducing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	COOH	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	terminally	_	ADV	_	_	_	_	_	_
19	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	RARalpha	_	PROPN	_	Number=Sing	_	_	_	_
21	exhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	negative	_	ADJ	_	Degree=Pos	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	RARalpha403	_	X	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	into	_	ADP	_	_	_	_	_	_
30	normal	_	ADJ	_	Degree=Pos	_	_	_	_
31	mouse	_	NOUN	_	Number=Sing	_	_	_	_
32	bone	_	NOUN	_	Number=Sing	_	_	_	_
33	marrow	_	NOUN	_	Number=Sing	_	_	_	_
34	generates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
36	growth	_	NOUN	_	Number=Sing	_	_	_	_
37	factor	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	lines	_	NOUN	_	Number=Plur	_	_	_	_
42	frozen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	at	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	multipotent	_	ADJ	_	Degree=Pos	_	_	_	_
46	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	EML	_	PROPN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	or	_	CCONJ	_	_	_	_	_	_
51	committed	_	ADJ	_	Degree=Pos	_	_	_	_
52	promyelocyte	_	NOUN	_	Number=Sing	_	_	_	_
53	(	_	PUNCT	_	_	_	_	_	_
54	MPRO	_	NOUN	_	Number=Sing	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	stages	_	NOUN	_	Number=Plur	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Nevertheless	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	relatively	_	ADV	_	_	_	_	_	_
4	high	_	ADJ	_	Degree=Pos	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	pharmacological	_	ADJ	_	Degree=Pos	_	_	_	_
7	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	RA	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	10	_	NUM	_	NumType=Card	_	_	_	_
14	&	_	CCONJ	_	_	_	_	_	_
15	mgr	_	NOUN	_	Number=Sing	_	_	_	_
16	;	_	PUNCT	_	_	_	_	_	_
17	M	_	X	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	overcome	_	VERB	_	VerbForm=Inf	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	blocks	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
25	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
26	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
27	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	MPRO	_	PROPN	_	Number=Sing	_	_	_	_
31	promyelocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	while	_	SCONJ	_	_	_	_	_	_
33	potentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
34	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	3	_	NUM	_	NumType=Card	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	IL	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	3	_	NUM	_	NumType=Card	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	commitment	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	EML	_	PROPN	_	Number=Sing	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	to	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
51	/	_	PUNCT	_	_	_	_	_	_
52	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
53	lineage	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	utilized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	RXR	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	RAR	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	agonists	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	antagonists	_	NOUN	_	Number=Plur	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
19	how	_	ADV	_	PronType=Int	_	_	_	_
20	RA	_	PROPN	_	Number=Sing	_	_	_	_
21	overcomes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	negative	_	ADJ	_	Degree=Pos	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	RARalpha	_	PROPN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
33	different	_	ADJ	_	Degree=Pos	_	_	_	_
34	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
35	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
36	stages	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Unexpectedly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	RXR	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	rather	_	ADV	_	_	_	_	_	_
12	than	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	RAR	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	agonist	_	ADJ	_	Number=Sing	_	_	_	_
19	induces	_	VERB	_	Number=Sing	_	_	_	_
20	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
21	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	MPRO	_	NOUN	_	Number=Sing	_	_	_	_
25	promyelocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
29	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	DNA	_	NOUN	_	Number=Sing	_	_	_	_
36	response	_	NOUN	_	Number=Sing	_	_	_	_
37	elements	_	NOUN	_	Number=Plur	_	_	_	_
38	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	RAR	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	RXR	_	PROPN	_	Number=Sing	_	_	_	_
43	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
44	rather	_	ADV	_	_	_	_	_	_
45	than	_	ADP	_	_	_	_	_	_
46	RXR	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	RXR	_	NOUN	_	Number=Sing	_	_	_	_
49	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	RXR	_	PROPN	_	Number=Sing	_	_	_	_
3	agonist	_	NOUN	_	Number=Sing	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	RAR	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	antagonists	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
14	extensive	_	ADJ	_	Degree=Pos	_	_	_	_
15	cross	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	talk	_	NOUN	_	Number=Sing	_	_	_	_
18	between	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	partners	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	RXR	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	RARalpha403	_	PROPN	_	Number=Sing	_	_	_	_
26	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	more	_	ADV	_	_	_	_	_	_
7	immature	_	ADJ	_	Degree=Pos	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	multipotent	_	ADJ	_	Degree=Pos	_	_	_	_
10	EML	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	RXR	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	agonist	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
22	either	_	CCONJ	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	potentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	3	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
30	commitment	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	EML	_	PROPN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
37	lineage	_	NOUN	_	Number=Sing	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	in	_	SCONJ	_	_	_	_	_	_
40	transactivating	_	VERB	_	VerbForm=Ger	_	_	_	_
41	RAR	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	RXR	_	PROPN	_	Number=Sing	_	_	_	_
44	response	_	NOUN	_	Number=Sing	_	_	_	_
45	elements	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	RA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	GALdbd	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	RARalpha	_	PROPN	_	Number=Sing	_	_	_	_
7	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	multipotent	_	ADJ	_	Degree=Pos	_	_	_	_
16	EML	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	harbor	_	VERB	_	Number=Sing	_	_	_	_
19	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	hormone	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	histone	_	NOUN	_	Number=Sing	_	_	_	_
5	deacetylase	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	HDAC	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
10	trichostatin	_	NOUN	_	Number=Sing	_	_	_	_
11	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	readily	_	ADV	_	_	_	_	_	_
13	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	RXR	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	RAR	_	NOUN	_	Number=Sing	_	_	_	_
18	reporter	_	NOUN	_	Number=Sing	_	_	_	_
19	construct	_	VERB	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	multipotent	_	ADJ	_	Degree=Pos	_	_	_	_
23	EML	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	not	_	ADV	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	committed	_	ADJ	_	Degree=Pos	_	_	_	_
30	MPRO	_	NOUN	_	Number=Sing	_	_	_	_
31	promyelocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
34	that	_	SCONJ	_	_	_	_	_	_
35	differences	_	NOUN	_	Number=Plur	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	HDAC	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
40	repressor	_	NOUN	_	Number=Sing	_	_	_	_
41	complexes	_	NOUN	_	Number=Plur	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
44	two	_	NUM	_	NumType=Card	_	_	_	_
45	closely	_	ADV	_	_	_	_	_	_
46	related	_	ADJ	_	Degree=Pos	_	_	_	_
47	but	_	CCONJ	_	_	_	_	_	_
48	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
49	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
50	lineages	_	NOUN	_	Number=Plur	_	_	_	_
51	might	_	AUX	_	VerbForm=Fin	_	_	_	_
52	account	_	VERB	_	VerbForm=Inf	_	_	_	_
53	for	_	ADP	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	differential	_	ADJ	_	Degree=Pos	_	_	_	_
56	activation	_	NOUN	_	Number=Sing	_	_	_	_
57	of	_	ADP	_	_	_	_	_	_
58	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
59	RXR	_	PROPN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	RARalpha403	_	PROPN	_	Number=Sing	_	_	_	_
62	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
63	that	_	PRON	_	PronType=Rel	_	_	_	_
64	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
65	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
66	at	_	ADP	_	_	_	_	_	_
67	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
68	different	_	ADJ	_	Degree=Pos	_	_	_	_
69	stages	_	NOUN	_	Number=Plur	_	_	_	_
70	of	_	ADP	_	_	_	_	_	_
71	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
72	development	_	NOUN	_	Number=Sing	_	_	_	_
73	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003143	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	concentration	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	1,25	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_

1	D3	_	VERB	_	Number=Sing	_	_	_	_
2	receptors	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
5	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	patients	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	X	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	hypophosphatemic	_	ADJ	_	Degree=Pos	_	_	_	_
14	rickets	_	NOUN	_	Number=Plur	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	effect	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	phosphate	_	NOUN	_	Number=Sing	_	_	_	_
19	supplementation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
2	renal	_	ADJ	_	Number=Sing	_	_	_	_
3	tubular	_	ADJ	_	Degree=Pos	_	_	_	_
4	phosphate	_	NOUN	_	Number=Sing	_	_	_	_
5	transport	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	considered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	primary	_	ADJ	_	Degree=Pos	_	_	_	_
12	defect	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	X	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	hypophosphatemic	_	ADJ	_	Degree=Pos	_	_	_	_
18	rickets	_	NOUN	_	Number=Plur	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	XLH	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	resistance	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	vitamin	_	VERB	_	Number=Sing	_	_	_	_
7	D	_	PROPN	_	Number=Sing	_	_	_	_
8	treatment	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	XLH	_	PROPN	_	Number=Sing	_	_	_	_
11	can	_	AUX	_	VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	explained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	hypophosphatemia	_	NOUN	_	Number=Sing	_	_	_	_
17	alone	_	ADV	_	_	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	most	_	ADJ	_	Degree=Sup	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	actions	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
8	D	_	PROPN	_	Number=Sing	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	receptors	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	VDR	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	VDR	_	PROPN	_	Number=Sing	_	_	_	_
21	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
23	postulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	XLH	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	possibility	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	measured	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	concentration	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	VDR	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	PHA	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
19	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	10	_	NUM	_	NumType=Card	_	_	_	_
23	XLH	_	ADJ	_	Number=Sing	_	_	_	_
24	patients	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Patients	_	NOUN	_	Number=Plur	_	_	_	_
2	without	_	ADP	_	_	_	_	_	_
3	phosphate	_	ADJ	_	Number=Sing	_	_	_	_
4	supplementation	_	NOUN	_	Number=Sing	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	significantly	_	ADV	_	_	_	_	_	_
7	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
8	concentration	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	21.7	_	NUM	_	NumType=Card	_	_	_	_
11	+/-	_	SYM	_	_	_	_	_	_
12	5.1	_	NUM	_	NumType=Card	_	_	_	_
13	fmol	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	mg	_	NOUN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	mean	_	VERB	_	Number=Sing	_	_	_	_
19	+/-	_	SYM	_	_	_	_	_	_
20	SEM	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	normal	_	ADJ	_	Degree=Pos	_	_	_	_
26	controls	_	NOUN	_	Number=Plur	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	60.7	_	NUM	_	NumType=Card	_	_	_	_
29	+/-	_	SYM	_	_	_	_	_	_
30	4.0	_	NUM	_	NumType=Card	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	contrary	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	there	_	PRON	_	_	_	_	_	_
6	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	no	_	DET	_	_	_	_	_	_
8	significant	_	ADJ	_	Degree=Pos	_	_	_	_
9	difference	_	NOUN	_	Number=Sing	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	phosphate	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	supplemented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	patients	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	58.3	_	NUM	_	NumType=Card	_	_	_	_
18	+/-	_	SYM	_	_	_	_	_	_
19	2.7	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	controls	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	significant	_	ADJ	_	Degree=Pos	_	_	_	_
5	positive	_	ADJ	_	Degree=Pos	_	_	_	_
6	correlation	_	NOUN	_	Number=Sing	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	VDR	_	NOUN	_	Number=Sing	_	_	_	_
9	concentration	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	serum	_	NOUN	_	Number=Sing	_	_	_	_
12	phosphate	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	P	_	NOUN	_	Number=Sing	_	_	_	_
15	less	_	ADJ	_	Degree=Cmp	_	_	_	_
16	than	_	ADP	_	_	_	_	_	_
17	0.05	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	patients	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	VDR	_	PROPN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	after	_	SCONJ	_	_	_	_	_	_
9	daily	_	ADJ	_	Degree=Pos	_	_	_	_
10	phosphate	_	NOUN	_	Number=Sing	_	_	_	_
11	supplementation	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	started	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	concentration	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	VDR	_	NOUN	_	Number=Sing	_	_	_	_
10	secondary	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
13	hypophosphatemia	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	one	_	NUM	_	NumType=Card	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	causes	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
21	D	_	NOUN	_	Number=Sing	_	_	_	_
22	resistance	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	XLH	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003144	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Spi-C	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	Ets	_	PROPN	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	temporally	_	ADV	_	_	_	_	_	_
10	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
14	development	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	Ets	_	NOUN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	yeast	_	ADV	_	Number=Sing	_	_	_	_
9	one	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
12	screening	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
16	library	_	NOUN	_	Number=Sing	_	_	_	_
17	made	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	mouse	_	NOUN	_	Number=Sing	_	_	_	_
23	splenic	_	ADJ	_	Number=Sing	_	_	_	_
24	B	_	ADJ	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	using	_	VERB	_	VerbForm=Ger	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	SP6	_	PROPN	_	Number=Sing	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	promoter	_	NOUN	_	Number=Sing	_	_	_	_
32	kappaY	_	NOUN	_	Number=Sing	_	_	_	_
33	element	_	NOUN	_	Number=Sing	_	_	_	_
34	as	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	bait	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	Ets	_	PROPN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	most	_	ADV	_	_	_	_	_	_
7	closely	_	ADV	_	_	_	_	_	_
8	related	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Spi-B	_	ADJ	_	Number=Sing	_	_	_	_
13	within	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	DNA	_	PROPN	_	Number=Sing	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	Ets	_	PROPN	_	Number=Sing	_	_	_	_
18	domain	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	therefore	_	ADV	_	_	_	_	_	_
22	named	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	Spi-C	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Spi	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	C	_	PROPN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	novel	_	NOUN	_	Number=Sing	_	_	_	_
10	subgroup	_	NOUN	_	Number=Sing	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	Ets	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	family	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	as	_	SCONJ	_	_	_	_	_	_
18	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
19	differed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	significantly	_	ADV	_	_	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	Spi-B	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	PU.	_	NOUN	_	Number=Sing	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	within	_	ADP	_	_	_	_	_	_
27	helix	_	NOUN	_	Number=Sing	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	Ets	_	NOUN	_	Number=Sing	_	_	_	_
32	domain	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Spi	_	PROPN	_	Number=Sing	_	_	_	_
2	-C	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	encoded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	single	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	copy	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	mapped	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	chromosome	_	NOUN	_	VerbForm=Inf	_	_	_	_
16	10	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	region	_	NOUN	_	Number=Sing	_	_	_	_
19	C.	_	PROPN	_	Number=Sing	_	_	_	_
20	Spi-C	_	PROPN	_	Number=Sing	_	_	_	_
21	interacted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	DNA	_	PROPN	_	Number=Sing	_	_	_	_
24	similarly	_	ADV	_	_	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
27	as	_	SCONJ	_	_	_	_	_	_
28	judged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	methylation	_	NOUN	_	Number=Sing	_	_	_	_
31	interference	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	band	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	shift	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	site	_	NOUN	_	Number=Sing	_	_	_	_
38	selection	_	NOUN	_	Number=Sing	_	_	_	_
39	analysis	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	transcription	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
46	kappaY	_	NOUN	_	Number=Sing	_	_	_	_
47	element	_	NOUN	_	Number=Sing	_	_	_	_
48	reporter	_	NOUN	_	Number=Sing	_	_	_	_
49	gene	_	NOUN	_	Number=Sing	_	_	_	_
50	upon	_	ADP	_	_	_	_	_	_
51	co-transfection	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
54	cells	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Spi	_	PROPN	_	Number=Sing	_	_	_	_
2	-C	_	PROPN	_	Number=Sing	_	_	_	_
3	RNA	_	PROPN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	mature	_	ADJ	_	Degree=Pos	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
13	levels	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	plasma	_	NOUN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	Spi-C	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	negative	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	Spi	_	PROPN	_	Number=Sing	_	_	_	_
17	-C	_	NOUN	_	Number=Sing	_	_	_	_
18	might	_	AUX	_	VerbForm=Fin	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	molecule	_	NOUN	_	Number=Sing	_	_	_	_
23	during	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	phase	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
30	development	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003147	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	nucleoside	_	ADJ	_	Degree=Pos	_	_	_	_
5	diphosphate	_	NOUN	_	Number=Sing	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	skin	_	NOUN	_	Number=Sing	_	_	_	_
10	cancers	_	NOUN	_	Number=Plur	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	immunohistochemical	_	ADJ	_	Degree=Pos	_	_	_	_
14	study	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nucleoside	_	ADJ	_	Degree=Pos	_	_	_	_
4	diphosphate	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	NDP	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	nm23	_	NOUN	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	product	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	variety	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	species	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	be	_	AUX	_	VerbForm=Inf	_	_	_	_
29	inversely	_	ADV	_	_	_	_	_	_
30	associated	_	VERB	_	Degree=Pos	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	metastatic	_	ADJ	_	Degree=Pos	_	_	_	_
33	potential	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	relationship	_	NOUN	_	Number=Sing	_	_	_	_
5	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	controversial	_	ADJ	_	Degree=Pos	_	_	_	_
7	according	_	VERB	_	VerbForm=Ger	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	tumor	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	types	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	experimental	_	ADJ	_	Degree=Pos	_	_	_	_
15	system	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	conflicting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	results	_	NOUN	_	Number=Plur	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	different	_	ADJ	_	Degree=Pos	_	_	_	_
22	research	_	NOUN	_	Number=Sing	_	_	_	_
23	groups	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
5	whether	_	SCONJ	_	_	_	_	_	_
6	NDP	_	PROPN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	serves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	marker	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	metastatic	_	ADJ	_	Degree=Pos	_	_	_	_
15	potential	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	skin	_	NOUN	_	Number=Sing	_	_	_	_
19	cancer	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
22	assessed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	levels	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NDP	_	PROPN	_	Number=Sing	_	_	_	_
27	kinase	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	9	_	NUM	_	NumType=Card	_	_	_	_
31	keratoacanthomas	_	NOUN	_	Number=Plur	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	KAs	_	PROPN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	26	_	NUM	_	NumType=Card	_	_	_	_
37	squamous	_	ADJ	_	Degree=Pos	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	carcinomas	_	NOUN	_	Number=Plur	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	SCCs	_	NOUN	_	Number=Plur	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	25	_	NUM	_	NumType=Card	_	_	_	_
46	basal	_	ADJ	_	Degree=Pos	_	_	_	_
47	cell	_	NOUN	_	Number=Sing	_	_	_	_
48	carcinomas	_	NOUN	_	Number=Plur	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	BCCs	_	NOUN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	using	_	VERB	_	VerbForm=Ger	_	_	_	_
53	immunohistochemistry	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NDP	_	PROPN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	intense	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	KA	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	SCC	_	PROPN	_	Number=Sing	_	_	_	_
12	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	BCC	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	difference	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NDP	_	PROPN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	KA	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	SCC	_	PROPN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	statistically	_	ADV	_	_	_	_	_	_
16	significant	_	ADJ	_	Degree=Pos	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	And	_	CCONJ	_	_	_	_	_	_
2	there	_	PRON	_	_	_	_	_	_
3	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	no	_	DET	_	_	_	_	_	_
5	statistically	_	ADV	_	_	_	_	_	_
6	significant	_	ADJ	_	Degree=Pos	_	_	_	_
7	difference	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	NDP	_	PROPN	_	Number=Sing	_	_	_	_
10	kinase	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	between	_	ADP	_	_	_	_	_	_
13	SCC	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	metastasis	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	SCC	_	NOUN	_	Number=Sing	_	_	_	_
18	without	_	ADP	_	_	_	_	_	_
19	metastasis	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	contradict	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
6	concerning	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	possible	_	ADJ	_	Degree=Pos	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	nm23	_	NOUN	_	Degree=Pos	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	metastatic	_	ADJ	_	Degree=Pos	_	_	_	_
16	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	skin	_	NOUN	_	Number=Sing	_	_	_	_
21	cancer	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	various	_	ADJ	_	Degree=Pos	_	_	_	_
7	tumor	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	types	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	biological	_	ADJ	_	Degree=Pos	_	_	_	_
13	significance	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	cutaneous	_	ADJ	_	Degree=Pos	_	_	_	_
16	carcinogenesis	_	NOUN	_	Number=Sing	_	_	_	_
17	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003150	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
2	receptors	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	down	_	ADV	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	regulated	_	VERB	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	inflamed	_	VERB	_	Degree=Pos	_	_	_	_
9	colonic	_	ADJ	_	Degree=Pos	_	_	_	_
10	mucosa	_	NOUN	_	Number=Sing	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
15	blood	_	NOUN	_	Number=Sing	_	_	_	_
16	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	patients	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	bowel	_	NOUN	_	Number=Sing	_	_	_	_
23	disease	_	NOUN	_	Number=Sing	_	_	_	_
24	[	_	PUNCT	_	_	_	_	_	_
25	see	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
26	comments	_	NOUN	_	Number=Plur	_	_	_	_
27	]	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Growing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	evidence	_	NOUN	_	Number=Sing	_	_	_	_
5	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	immune	_	NOUN	_	Number=Sing	_	_	_	_
9	system	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	hypothalamic	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	adrenal	_	NOUN	_	Degree=Pos	_	_	_	_
17	system	_	NOUN	_	Number=Sing	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	several	_	ADJ	_	Degree=Pos	_	_	_	_
22	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	example	_	NOUN	_	Number=Sing	_	_	_	_
26	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
27	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
28	receptors	_	NOUN	_	Number=Plur	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	hGR	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	standard	_	ADJ	_	Degree=Pos	_	_	_	_
5	treatment	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	acute	_	ADJ	_	Degree=Pos	_	_	_	_
8	attacks	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	bowel	_	NOUN	_	Number=Sing	_	_	_	_
12	disease	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	IBD	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	hGR	_	VERB	_	VerbForm=Inf	_	_	_	_
6	down	_	ADP	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	can	_	AUX	_	VerbForm=Fin	_	_	_	_
16	propagate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	IBD	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	PATIENTS	_	NOUN	_	Number=Plur	_	_	_	_
2	AND	_	CCONJ	_	_	_	_	_	_
3	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_

1	IBD	_	ADJ	_	Degree=Pos	_	_	_	_
2	patients	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	either	_	CCONJ	_	_	_	_	_	_
5	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	5-60	_	NUM	_	NumType=Card	_	_	_	_
8	mg	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	prednisolone	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	more	_	ADJ	_	Degree=Cmp	_	_	_	_
13	than	_	ADP	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	week	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	without	_	ADP	_	_	_	_	_	_
19	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
20	treatment	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	more	_	ADJ	_	Degree=Cmp	_	_	_	_
23	than	_	ADP	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	weeks	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	hGR	_	NOUN	_	Number=Sing	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
10	blood	_	NOUN	_	Number=Sing	_	_	_	_
11	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	PBMCs	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	mucosal	_	ADJ	_	Degree=Pos	_	_	_	_
18	biopsies	_	NOUN	_	Number=Plur	_	_	_	_
19	using	_	VERB	_	VerbForm=Ger	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	radioassay	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	[	_	PUNCT	_	_	_	_	_	_
24	3H]-	_	ADJ	_	NumType=Card	_	_	_	_
25	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	6	_	NUM	_	NumType=Card	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	immunosorbent	_	PROPN	_	Degree=Pos	_	_	_	_
14	assay	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	ELISA	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	systemic	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	hGR	_	NOUN	_	Number=Sing	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	corticosteroid	_	ADJ	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	IBD	_	ADJ	_	Number=Sing	_	_	_	_
15	patients	_	NOUN	_	Number=Plur	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	significantly	_	ADV	_	_	_	_	_	_
18	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
19	than	_	ADP	_	_	_	_	_	_
20	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	control	_	NOUN	_	Number=Sing	_	_	_	_
23	subjects	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	59.6	_	NUM	_	NumType=Card	_	_	_	_
26	+/-	_	SYM	_	_	_	_	_	_
27	57.1	_	NUM	_	NumType=Card	_	_	_	_
28	dpm	_	NOUN	_	Number=Sing	_	_	_	_
29	mg	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
33	protein	_	NOUN	_	Number=Sing	_	_	_	_
34	vs.	_	ADP	_	_	_	_	_	_
35	227.0	_	NUM	_	NumType=Card	_	_	_	_
36	+/-	_	SYM	_	_	_	_	_	_
37	90.8	_	NUM	_	NumType=Card	_	_	_	_
38	dpm	_	NOUN	_	Number=Sing	_	_	_	_
39	mg	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
43	protein	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	P	_	NOUN	_	Number=Sing	_	_	_	_
46	=	_	SYM	_	_	_	_	_	_
47	0.007	_	NUM	_	NumType=Card	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	IBD	_	ADJ	_	Number=Sing	_	_	_	_
51	patients	_	NOUN	_	Number=Plur	_	_	_	_
52	not	_	ADV	_	_	_	_	_	_
53	receiving	_	VERB	_	VerbForm=Ger	_	_	_	_
54	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
55	treatment	_	NOUN	_	Number=Sing	_	_	_	_
56	(	_	PUNCT	_	_	_	_	_	_
57	179.7	_	NUM	_	NumType=Card	_	_	_	_
58	+/-	_	SYM	_	_	_	_	_	_
59	171.3	_	NUM	_	NumType=Card	_	_	_	_
60	dpm	_	NOUN	_	Number=Sing	_	_	_	_
61	mg	_	NOUN	_	Number=Sing	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	1	_	NUM	_	NumType=Card	_	_	_	_
64	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
65	protein	_	NOUN	_	Number=Sing	_	_	_	_
66	,	_	PUNCT	_	_	_	_	_	_
67	P	_	NOUN	_	Number=Sing	_	_	_	_
68	=	_	SYM	_	_	_	_	_	_
69	0.002	_	NUM	_	NumType=Card	_	_	_	_
70	)	_	PUNCT	_	_	_	_	_	_
71	.	_	PUNCT	_	_	_	_	_	_

1	Systemic	_	ADJ	_	Degree=Pos	_	_	_	_
2	hGR	_	NOUN	_	Number=Sing	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
6	IBD	_	ADJ	_	Number=Sing	_	_	_	_
7	patients	_	NOUN	_	Number=Plur	_	_	_	_
8	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	differ	_	VERB	_	VerbForm=Inf	_	_	_	_
11	significantly	_	ADV	_	_	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	control	_	NOUN	_	Number=Sing	_	_	_	_
16	subjects	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	patients	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	connective	_	ADJ	_	Degree=Pos	_	_	_	_
5	tissue	_	NOUN	_	Number=Sing	_	_	_	_
6	diseases	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	systemic	_	ADJ	_	Degree=Pos	_	_	_	_
9	hGR	_	NOUN	_	Number=Sing	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	absence	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
22	treatment	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Systemic	_	ADJ	_	Degree=Pos	_	_	_	_
2	hGR	_	NOUN	_	Number=Sing	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	patients	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	Crohn	_	PROPN	_	Number=Sing	_	_	_	_
8	's	_	PART	_	_	_	_	_	_
9	disease	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	CD	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	steroids	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	66.6	_	NUM	_	NumType=Card	_	_	_	_
18	+/-	_	SYM	_	_	_	_	_	_
19	61.0	_	NUM	_	NumType=Card	_	_	_	_
20	dpm	_	NOUN	_	Number=Sing	_	_	_	_
21	mg	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	different	_	ADJ	_	Degree=Pos	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	patients	_	NOUN	_	Number=Plur	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	ulcerative	_	ADJ	_	Degree=Pos	_	_	_	_
36	colitis	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	UC	_	PROPN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	56.1	_	NUM	_	NumType=Card	_	_	_	_
42	+/-	_	SYM	_	_	_	_	_	_
43	51.6	_	NUM	_	NumType=Card	_	_	_	_
44	dpm	_	NOUN	_	Number=Sing	_	_	_	_
45	mg	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
49	protein	_	NOUN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	findings	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	mucosal	_	ADJ	_	Degree=Pos	_	_	_	_
8	hGR	_	NOUN	_	Number=Sing	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	significantly	_	ADV	_	_	_	_	_	_
12	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	both	_	DET	_	_	_	_	_	_
15	steroid	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	18.0	_	NUM	_	NumType=Card	_	_	_	_
20	+/-	_	SYM	_	_	_	_	_	_
21	15.5	_	NUM	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	not	_	ADV	_	_	_	_	_	_
25	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	37.8	_	NUM	_	NumType=Card	_	_	_	_
30	+/-	_	SYM	_	_	_	_	_	_
31	30.5	_	NUM	_	NumType=Card	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	patients	_	NOUN	_	Number=Plur	_	_	_	_
34	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	control	_	NOUN	_	Number=Sing	_	_	_	_
37	subjects	_	NOUN	_	Number=Plur	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	125.6	_	NUM	_	NumType=Card	_	_	_	_
40	+/-	_	SYM	_	_	_	_	_	_
41	97.1	_	NUM	_	NumType=Card	_	_	_	_
42	;	_	PUNCT	_	_	_	_	_	_
43	P	_	NOUN	_	Number=Sing	_	_	_	_
44	=	_	SYM	_	_	_	_	_	_
45	0.00009	_	NUM	_	NumType=Card	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	P	_	NOUN	_	Number=Sing	_	_	_	_
48	=	_	SYM	_	_	_	_	_	_
49	0.0008	_	NUM	_	NumType=Card	_	_	_	_
50	respectively	_	ADV	_	_	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	6	_	NUM	_	NumType=Card	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	all	_	DET	_	_	_	_	_	_
7	IBD	_	PROPN	_	Number=Sing	_	_	_	_
8	groups	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	without	_	SCONJ	_	_	_	_	_	_
12	steroids	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	significantly	_	ADV	_	_	_	_	_	_
15	different	_	ADJ	_	Degree=Pos	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	control	_	NOUN	_	Number=Sing	_	_	_	_
20	subjects	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSION	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	In	_	ADP	_	_	_	_	_	_
4	IBD	_	NOUN	_	Number=Sing	_	_	_	_
5	there	_	PRON	_	_	_	_	_	_
6	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	no	_	DET	_	_	_	_	_	_
8	difference	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	systemic	_	ADJ	_	Degree=Pos	_	_	_	_
11	hGR	_	NOUN	_	Number=Sing	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	between	_	ADP	_	_	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	steroid	_	ADJ	_	Degree=Pos	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	patients	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	control	_	NOUN	_	Number=Sing	_	_	_	_
21	subjects	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	spite	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	6	_	NUM	_	NumType=Card	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Mucosal	_	ADJ	_	Degree=Pos	_	_	_	_
2	hGR	_	NOUN	_	Number=Sing	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	independently	_	ADV	_	_	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	treatment	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	probably	_	ADV	_	_	_	_	_	_
11	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	protection	_	NOUN	_	Number=Sing	_	_	_	_
16	against	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	action	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	intestinal	_	ADJ	_	Degree=Pos	_	_	_	_
24	mucosa	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003152	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	tal	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	GATA	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Tal	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	nearly	_	ADV	_	_	_	_	_	_
9	30	_	NUM	_	NumType=Card	_	_	_	_
10	%	_	SYM	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	acute	_	ADJ	_	Degree=Pos	_	_	_	_
15	lymphoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
16	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Tal	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	putative	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	basic	_	ADJ	_	Degree=Pos	_	_	_	_
13	helix	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	loop	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	helix	_	NOUN	_	Number=Sing	_	_	_	_
18	domain	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	predominantly	_	ADV	_	_	_	_	_	_
25	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	pattern	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	tal	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	situ	_	NOUN	_	Number=Sing	_	_	_	_
18	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	reverse	_	NOUN	_	Number=Sing	_	_	_	_
21	transcriptase	_	NOUN	_	Number=Sing	_	_	_	_
22	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
23	chain	_	NOUN	_	Number=Sing	_	_	_	_
24	reaction	_	NOUN	_	Number=Sing	_	_	_	_
25	analysis	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	methods	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	tal	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	megakaryocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
16	as	_	ADV	_	_	_	_	_	_
17	well	_	ADV	_	Degree=Pos	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	basophilic	_	ADJ	_	Degree=Pos	_	_	_	_
21	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	tal	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	1A	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	consensus	_	NOUN	_	Number=Sing	_	_	_	_
19	GATA	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	sites	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	active	_	ADJ	_	Degree=Pos	_	_	_	_
26	mainly	_	ADV	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	lineages	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	GATA	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	several	_	ADJ	_	Degree=Pos	_	_	_	_
12	genes	_	NOUN	_	Number=Plur	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	mastocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	basophilic	_	ADJ	_	Degree=Pos	_	_	_	_
24	lineages	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
27	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	GATA	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
34	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	GATA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	tal	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	coexpressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
16	three	_	NUM	_	NumType=Card	_	_	_	_
17	lineages	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Remarkably	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	both	_	DET	_	_	_	_	_	_
7	genes	_	NOUN	_	Number=Plur	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	downmodulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	during	_	ADP	_	_	_	_	_	_
11	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
14	terminal	_	NOUN	_	Number=Sing	_	_	_	_
15	maturation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	immature	_	ADJ	_	Degree=Pos	_	_	_	_
3	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	tal	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	GATA	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	coexpressed	_	VERB	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	committed	_	VERB	_	Degree=Pos	_	_	_	_
18	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	CD34+/	_	PROPN	_	Number=Sing	_	_	_	_
22	CD38	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	+	_	SYM	_	_	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	whereas	_	SCONJ	_	_	_	_	_	_
30	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
31	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	not	_	PART	_	_	_	_	_	_
33	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	most	_	ADV	_	_	_	_	_	_
37	primitive	_	ADJ	_	Degree=Pos	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	CD34	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	2	_	NUM	_	NumType=Card	_	_	_	_
43	+	_	SYM	_	_	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	/	_	PUNCT	_	_	_	_	_	_
46	CD38	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	GATA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	strongly	_	ADV	_	_	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	both	_	DET	_	_	_	_	_	_
12	most	_	ADV	_	_	_	_	_	_
13	primitive	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	committed	_	ADJ	_	Degree=Pos	_	_	_	_
16	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	whereas	_	SCONJ	_	_	_	_	_	_
20	GATA	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	3	_	NUM	_	NumType=Card	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	mostly	_	ADV	_	_	_	_	_	_
25	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	most	_	ADJ	_	_	_	_	_	_
28	primitive	_	ADJ	_	Degree=Pos	_	_	_	_
29	ones	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Altogether	_	ADV	_	_	_	_	_	_
2	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
3	results	_	NOUN	_	Number=Plur	_	_	_	_
4	strongly	_	ADV	_	_	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	GATA	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	modulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	tal	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	basosophilic	_	ADJ	_	Degree=Pos	_	_	_	_
28	lineages	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003154	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	CD4	_	NOUN	_	Number=Sing	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	Interaction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	VLA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	5	_	NUM	_	NumType=Card	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	CD4	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Fibronectin	_	PROPN	_	Number=Sing	_	_	_	_
2	synergized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	anti-CD3	_	ADJ	_	Degree=Pos	_	_	_	_
5	antibody	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
8	CD4	_	PROPN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	serum	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	free	_	ADJ	_	Degree=Pos	_	_	_	_
16	culture	_	NOUN	_	Number=Sing	_	_	_	_
17	system	_	NOUN	_	Number=Sing	_	_	_	_
18	whereas	_	SCONJ	_	_	_	_	_	_
19	no	_	DET	_	_	_	_	_	_
20	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	when	_	ADV	_	PronType=Int	_	_	_	_
24	CD4	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	cultured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
30	alone	_	ADJ	_	_	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
33	alone	_	ADV	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	anti-CD29	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	integrin	_	NOUN	_	Number=Sing	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	as	_	ADV	_	_	_	_	_	_
11	well	_	ADV	_	Degree=Pos	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	anti-VLA	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	5	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
22	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
24	CD4	_	PROPN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
29	system	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
3	alone	_	ADV	_	_	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
6	alone	_	ADV	_	_	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	message	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	CD4	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	combination	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
22	plus	_	CCONJ	_	_	_	_	_	_
23	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
24	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	message	_	NOUN	_	Number=Sing	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	CD4	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
7	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	message	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	generated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
18	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	VLA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	5	_	NUM	_	NumType=Card	_	_	_	_
26	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	interaction	_	NOUN	_	Number=Sing	_	_	_	_
29	may	_	AUX	_	VerbForm=Fin	_	_	_	_
30	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
31	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	independent	_	ADJ	_	Degree=Pos	_	_	_	_
33	signal	_	NOUN	_	Number=Sing	_	_	_	_
34	distinct	_	NOUN	_	Number=Sing	_	_	_	_
35	from	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	CD3	_	PROPN	_	Number=Sing	_	_	_	_
38	pathway	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	induction	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
46	AP	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	1	_	NUM	_	NumType=Card	_	_	_	_
49	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
50	factor	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	VLA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	CD4	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	can	_	AUX	_	VerbForm=Fin	_	_	_	_
12	play	_	VERB	_	VerbForm=Inf	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	complementary	_	ADJ	_	Degree=Pos	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	CD3	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	TCR	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	VERB	_	Degree=Pos	_	_	_	_
22	signal	_	NOUN	_	Number=Sing	_	_	_	_
23	transduction	_	NOUN	_	Number=Sing	_	_	_	_
24	through	_	ADP	_	_	_	_	_	_
25	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	interaction	_	NOUN	_	Number=Sing	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003157	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Daidzein	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	genistein	_	VERB	_	Number=Sing	_	_	_	_
4	glucuronides	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	vitro	_	NOUN	_	Number=Sing	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	weakly	_	ADV	_	_	_	_	_	_
9	estrogenic	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	natural	_	ADJ	_	Degree=Pos	_	_	_	_
14	killer	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	nutritionally	_	ADV	_	_	_	_	_	_
18	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
19	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Daidzein	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	genistein	_	PROPN	_	Number=Sing	_	_	_	_
4	glucuronides	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	DG	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	GG	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	major	_	ADJ	_	Degree=Pos	_	_	_	_
12	isoflavone	_	NOUN	_	Number=Sing	_	_	_	_
13	metabolites	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	partly	_	ADV	_	_	_	_	_	_
18	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	biological	_	ADJ	_	Degree=Pos	_	_	_	_
21	effects	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	isoflavones	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	such	_	ADJ	_	Degree=Pos	_	_	_	_
26	as	_	ADP	_	_	_	_	_	_
27	estrogen	_	NOUN	_	Degree=Pos	_	_	_	_
28	receptor	_	NOUN	_	Number=Sing	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	natural	_	ADJ	_	Degree=Pos	_	_	_	_
32	killer	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	NK	_	PROPN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	DG	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	GG	_	PROPN	_	Number=Sing	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	synthesized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	using	_	VERB	_	VerbForm=Ger	_	_	_	_
7	3	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	methylcholanthrene	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	rat	_	NOUN	_	Number=Sing	_	_	_	_
13	liver	_	NOUN	_	Number=Sing	_	_	_	_
14	microsomes	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Km	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	Vmax	_	PROPN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	daidzein	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	genistein	_	NOUN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	9.0	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	7.7	_	NUM	_	NumType=Card	_	_	_	_
13	micromol	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	L	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	0.7	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	1.6	_	NUM	_	NumType=Card	_	_	_	_
21	micromol	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	mg	_	NOUN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	min	_	NOUN	_	Number=Plur	_	_	_	_
2	)	_	PUNCT	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	respectively	_	ADV	_	_	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	absence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	ultraviolet	_	ADJ	_	Number=Sing	_	_	_	_
5	absorbance	_	NOUN	_	Number=Sing	_	_	_	_
6	maxima	_	NOUN	_	Number=Sing	_	_	_	_
7	shifts	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	presence	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	sodium	_	NOUN	_	Number=Sing	_	_	_	_
13	acetate	_	NOUN	_	Number=Sing	_	_	_	_
14	confirmed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	products	_	NOUN	_	Number=Plur	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	7	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	O-	_	ADJ	_	_	_	_	_	_
23	glucuronides	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	DG	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	GG	_	PROPN	_	Number=Sing	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	further	_	ADV	_	_	_	_	_	_
6	purified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	Sephadex	_	PROPN	_	Number=Sing	_	_	_	_
10	LH	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	20	_	NUM	_	NumType=Card	_	_	_	_
13	column	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	DG	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	GG	_	PROPN	_	Number=Sing	_	_	_	_
4	competed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	17beta	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	3H	_	NUM	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	estradiol	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	estrogen	_	VERB	_	VerbForm=Inf	_	_	_	_
17	receptors	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	B6D2F1	_	NOUN	_	Number=Sing	_	_	_	_
20	mouse	_	NOUN	_	Number=Sing	_	_	_	_
21	uterine	_	NOUN	_	Number=Sing	_	_	_	_
22	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
3	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	50	_	NUM	_	NumType=Card	_	_	_	_
6	%	_	SYM	_	Number=Sing	_	_	_	_
7	displacement	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	17beta	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	3H	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	estradiol	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	CB50	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	17beta-estradiol	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	1.34	_	NUM	_	NumType=Card	_	_	_	_
23	nmol	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	L	_	NOUN	_	Number=Sing	_	_	_	_
26	;	_	PUNCT	_	_	_	_	_	_
27	diethylstilbestrol	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	1.46	_	NUM	_	NumType=Card	_	_	_	_
30	nmol	_	NOUN	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	L	_	NOUN	_	Number=Sing	_	_	_	_
33	;	_	PUNCT	_	_	_	_	_	_
34	daidzein	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_

1	1.6	_	NUM	_	NumType=Card	_	_	_	_
2	micromol	_	NOUN	_	Number=Sing	_	_	_	_
3	/	_	PUNCT	_	_	_	_	_	_
4	L	_	PROPN	_	Number=Sing	_	_	_	_
5	;	_	PUNCT	_	_	_	_	_	_
6	DG	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	14.7	_	NUM	_	NumType=Card	_	_	_	_
9	micromol	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	L	_	NOUN	_	Number=Sing	_	_	_	_
12	;	_	PUNCT	_	_	_	_	_	_
13	genistein	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	0.154	_	NUM	_	NumType=Card	_	_	_	_
16	micromol	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	L	_	NOUN	_	Number=Sing	_	_	_	_
19	;	_	PUNCT	_	_	_	_	_	_
20	GG	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	7.27	_	NUM	_	NumType=Card	_	_	_	_
23	micromol	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	L	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
4	blood	_	NOUN	_	Number=Sing	_	_	_	_
5	NK	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	genistein	_	NOUN	_	Number=Sing	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	<	_	PUNCT	_	_	_	_	_	_
11	0.5	_	NUM	_	NumType=Card	_	_	_	_
12	micromol	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	L	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	DG	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	GG	_	PROPN	_	Number=Sing	_	_	_	_
19	at	_	ADP	_	_	_	_	_	_
20	0.1	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	SYM	_	_	_	_	_	_
22	10	_	NUM	_	NumType=Card	_	_	_	_
23	micromol	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	L	_	NOUN	_	Number=Sing	_	_	_	_
26	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	NK	_	PROPN	_	Number=Sing	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	K562	_	NUM	_	Number=Sing	_	_	_	_
32	cancer	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	killing	_	VERB	_	VerbForm=Ger	_	_	_	_
35	significantly	_	ADV	_	_	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	P	_	NOUN	_	Number=Sing	_	_	_	_
38	<	_	PUNCT	_	_	_	_	_	_
39	0.05	_	NUM	_	NumType=Card	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	>	_	SYM	_	_	_	_	_	_
3	0.5	_	NUM	_	NumType=Card	_	_	_	_
4	micromol	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	L	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	genistein	_	PROPN	_	Number=Sing	_	_	_	_
9	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	NK	_	PROPN	_	Number=Sing	_	_	_	_
11	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
12	significantly	_	ADV	_	_	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	P	_	NOUN	_	Number=Sing	_	_	_	_
15	<	_	PUNCT	_	_	_	_	_	_
16	0.05	_	NUM	_	NumType=Card	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	glucuronides	_	NOUN	_	Number=Plur	_	_	_	_
3	only	_	ADV	_	_	_	_	_	_
4	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	NK	_	PROPN	_	Number=Sing	_	_	_	_
6	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
7	at	_	ADP	_	_	_	_	_	_
8	50	_	NUM	_	NumType=Card	_	_	_	_
9	micromol	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	L.	_	PROPN	_	Number=Sing	_	_	_	_
12	Isoflavones	_	PROPN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	especially	_	ADV	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	isoflavone	_	ADJ	_	Number=Sing	_	_	_	_
18	glucuronides	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NK	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	additively	_	ADV	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
3	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	DG	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	GG	_	PROPN	_	Number=Sing	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	weakly	_	ADV	_	_	_	_	_	_
10	estrogenic	_	ADJ	_	Degree=Pos	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
14	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	NK	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	nutritionally	_	ADV	_	_	_	_	_	_
20	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
21	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	vitro	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	probably	_	ADV	_	_	_	_	_	_
26	at	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	site	_	NOUN	_	Number=Sing	_	_	_	_
29	different	_	NOUN	_	Number=Sing	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	action	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003160	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	TCF	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	DNA	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	uniquely	_	ADV	_	_	_	_	_	_
15	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	normal	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	neoplastic	_	ADJ	_	Degree=Pos	_	_	_	_
20	T-lineage	_	NOUN	_	Number=Sing	_	_	_	_
21	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	TCF	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	putative	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	affinity	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	sequence	_	NOUN	_	Number=Sing	_	_	_	_
16	motif	_	NOUN	_	Number=Sing	_	_	_	_
17	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	number	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	TCF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	originally	_	ADV	_	_	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	T	_	NUM	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	fashion	_	NOUN	_	Number=Sing	_	_	_	_
18	within	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	set	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	mouse	_	NOUN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	lines	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	reportedly	_	ADV	_	_	_	_	_	_
6	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
9	nonlymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
10	tissues	_	NOUN	_	Number=Plur	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	murine	_	NOUN	_	Number=Sing	_	_	_	_
13	embryogenesis	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	now	_	ADV	_	_	_	_	_	_
4	raised	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
7	antibody	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	document	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	biochemistry	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	TCF	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	expected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	TCF	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
11	only	_	ADV	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	lines	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	lineage	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	always	_	ADV	_	_	_	_	_	_
5	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Immunohistochemistry	_	NOUN	_	Number=Sing	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	panel	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	tissues	_	NOUN	_	Number=Plur	_	_	_	_
8	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	TCF	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	exclusively	_	ADV	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	CD3	_	PROPN	_	Number=Sing	_	_	_	_
23	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
5	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
6	tissues	_	NOUN	_	Number=Plur	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blotting	_	NOUN	_	Number=Sing	_	_	_	_
3	yielded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	set	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	bands	_	NOUN	_	Number=Plur	_	_	_	_
8	ranging	_	VERB	_	VerbForm=Ger	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	25	_	NUM	_	NumType=Card	_	_	_	_
11	kD	_	NOUN	_	Number=Plur	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	55	_	NUM	_	NumType=Card	_	_	_	_
14	kD	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	extensive	_	ADJ	_	Degree=Pos	_	_	_	_
19	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
20	splicing	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	TCF	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	all	_	DET	_	_	_	_	_	_
10	samples	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	set	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	22	_	NUM	_	NumType=Card	_	_	_	_
16	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
17	malignancies	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	various	_	ADJ	_	Degree=Pos	_	_	_	_
20	stages	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	maturation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	absent	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	large	_	ADJ	_	Degree=Pos	_	_	_	_
30	number	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	other	_	ADJ	_	Degree=Pos	_	_	_	_
33	hematologic	_	ADJ	_	Degree=Pos	_	_	_	_
34	neoplasms	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	imply	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	T	_	NOUN	_	NumType=Card	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	function	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	TCF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	notion	_	NOUN	_	Number=Sing	_	_	_	_
17	corroborated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	recent	_	ADJ	_	Degree=Pos	_	_	_	_
20	observations	_	NOUN	_	Number=Plur	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	Tcf	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	knock	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	out	_	NOUN	_	Number=Sing	_	_	_	_
28	mice	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	TCF	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	can	_	AUX	_	VerbForm=Fin	_	_	_	_
14	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	pan	_	NOUN	_	Number=Sing	_	_	_	_
18	-T	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	lineage	_	NOUN	_	Number=Sing	_	_	_	_
21	marker	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	diagnosis	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
27	malignancies	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003164	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	pseudo	_	VERB	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	hypoaldosteronism	_	NOUN	_	Number=Sing	_	_	_	_
5	following	_	VERB	_	VerbForm=Ger	_	_	_	_
6	resection	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	ileum	_	NOUN	_	Number=Sing	_	_	_	_
10	:	_	PUNCT	_	_	_	_	_	_
11	normal	_	ADJ	_	Degree=Pos	_	_	_	_
12	level	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	aldosterone	_	NOUN	_	Number=Sing	_	_	_	_
16	receptors	_	NOUN	_	Number=Plur	_	_	_	_
17	outside	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	acute	_	ADJ	_	Degree=Pos	_	_	_	_
20	phase	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Pseudo	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	hypoaldosteronism	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	PHA	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	due	_	ADP	_	_	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	mineralocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
11	resistance	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	manifests	_	VERB	_	Number=Plur	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	hyponatremia	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	hyperkalemia	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	plasma	_	NOUN	_	Number=Sing	_	_	_	_
21	aldosterone	_	NOUN	_	Number=Sing	_	_	_	_
22	levels	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	be	_	AUX	_	VerbForm=Inf	_	_	_	_
4	familial	_	ADJ	_	Degree=Pos	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	secondary	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
9	renal	_	ADJ	_	Degree=Pos	_	_	_	_
10	sodium	_	NOUN	_	Number=Sing	_	_	_	_
11	handling	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	case	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	54	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	year	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	old	_	ADJ	_	Degree=Pos	_	_	_	_
12	woman	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	multifocal	_	ADJ	_	Degree=Pos	_	_	_	_
15	cancer	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	colon	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	who	_	PRON	_	PronType=Rel	_	_	_	_
21	developed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	PHA	_	PROPN	_	Number=Sing	_	_	_	_
23	after	_	ADP	_	_	_	_	_	_
24	subtotal	_	ADJ	_	Degree=Pos	_	_	_	_
25	colectomy	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	ileal	_	ADJ	_	Degree=Pos	_	_	_	_
28	resection	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	jejunostomy	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	She	_	PRON	_	Case=Nom|Gender=Fem|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	6	_	NUM	_	NumType=Card	_	_	_	_
6	g	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	salt	_	NOUN	_	Number=Sing	_	_	_	_
9	daily	_	ADV	_	_	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
12	dehydration	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	she	_	PRON	_	Case=Nom|Gender=Fem|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	stopped	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	herself	_	PRON	_	Case=Acc|Gender=Fem|Number=Sing|Person=3|PronType=Prs|Reflex=Yes	_	_	_	_
18	because	_	ADP	_	_	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	fecal	_	ADJ	_	Degree=Pos	_	_	_	_
22	losses	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	month	_	NOUN	_	Number=Sing	_	_	_	_
3	later	_	ADV	_	Degree=Cmp	_	_	_	_
4	she	_	PRON	_	Case=Nom|Gender=Fem|Number=Sing|Person=3|PronType=Prs	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	admitted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	signs	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	acute	_	ADJ	_	Degree=Pos	_	_	_	_
11	adrenal	_	ADJ	_	Degree=Pos	_	_	_	_
12	failure	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	i.e.	_	X	_	_	_	_	_	_
15	fatigue	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	severe	_	ADJ	_	Degree=Pos	_	_	_	_
18	nausea	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	blood	_	NOUN	_	Number=Sing	_	_	_	_
21	pressure	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	80	_	NUM	_	NumType=Card	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	60	_	NUM	_	NumType=Card	_	_	_	_
26	mmHg	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
29	dehydration	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	hyponatremia	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	118	_	NUM	_	NumType=Card	_	_	_	_
34	mmol	_	NOUN	_	Number=Sing	_	_	_	_
35	/	_	PUNCT	_	_	_	_	_	_
36	l	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	;	_	PUNCT	_	_	_	_	_	_
39	hyperkalemia	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	7.6	_	NUM	_	NumType=Card	_	_	_	_
42	mmol	_	NOUN	_	Number=Sing	_	_	_	_
43	/	_	PUNCT	_	_	_	_	_	_
44	l	_	NOUN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	blood	_	NOUN	_	Number=Sing	_	_	_	_
49	urea	_	NOUN	_	Number=Sing	_	_	_	_
50	nitrogen	_	NOUN	_	Number=Sing	_	_	_	_
51	(	_	PUNCT	_	_	_	_	_	_
52	BUN	_	PROPN	_	Number=Sing	_	_	_	_
53	)	_	PUNCT	_	_	_	_	_	_
54	(	_	PUNCT	_	_	_	_	_	_
55	200	_	NUM	_	NumType=Card	_	_	_	_
56	mg	_	NOUN	_	Number=Sing	_	_	_	_
57	/	_	PUNCT	_	_	_	_	_	_
58	dl	_	NOUN	_	Number=Sing	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	and	_	CCONJ	_	_	_	_	_	_
61	creatininemia	_	NOUN	_	Number=Sing	_	_	_	_
62	(	_	PUNCT	_	_	_	_	_	_
63	2.5	_	NUM	_	NumType=Card	_	_	_	_
64	mg	_	NOUN	_	Number=Sing	_	_	_	_
65	/	_	PUNCT	_	_	_	_	_	_
66	dl	_	NOUN	_	Number=Sing	_	_	_	_
67	)	_	PUNCT	_	_	_	_	_	_
68	,	_	PUNCT	_	_	_	_	_	_
69	and	_	CCONJ	_	_	_	_	_	_
70	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
71	plasma	_	NOUN	_	Number=Sing	_	_	_	_
72	bicarbonates	_	NOUN	_	Number=Plur	_	_	_	_
73	level	_	NOUN	_	Number=Sing	_	_	_	_
74	(	_	PUNCT	_	_	_	_	_	_
75	HCO3	_	NOUN	_	Number=Sing	_	_	_	_
76	-:	_	PUNCT	_	_	_	_	_	_
77	16	_	NUM	_	NumType=Card	_	_	_	_
78	mmol	_	NOUN	_	Number=Sing	_	_	_	_
79	/	_	PUNCT	_	_	_	_	_	_
80	l	_	NOUN	_	Number=Sing	_	_	_	_
81	;	_	PUNCT	_	_	_	_	_	_
82	N	_	NOUN	_	Number=Sing	_	_	_	_
83	:	_	PUNCT	_	_	_	_	_	_
84	27-30	_	NUM	_	NumType=Card	_	_	_	_
85	)	_	PUNCT	_	_	_	_	_	_
86	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	plasma	_	NOUN	_	Number=Sing	_	_	_	_
5	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	high	_	ADJ	_	Degree=Pos	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	66	_	NUM	_	NumType=Card	_	_	_	_
10	microg	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	100	_	NUM	_	NumType=Card	_	_	_	_
13	ml	_	NOUN	_	Number=Sing	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	10:00	_	NUM	_	NumType=Card	_	_	_	_
16	h	_	NOUN	_	Number=Sing	_	_	_	_
17	;	_	PUNCT	_	_	_	_	_	_
18	N	_	NOUN	_	Number=Sing	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	8-15	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	ACTH	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	normal	_	ADJ	_	Degree=Pos	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	13	_	NUM	_	NumType=Card	_	_	_	_
29	pg	_	NOUN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	ml	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	N	_	NOUN	_	Number=Sing	_	_	_	_
34	:	_	PUNCT	_	_	_	_	_	_
35	10	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	SYM	_	_	_	_	_	_
37	60	_	NUM	_	NumType=Card	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	;	_	PUNCT	_	_	_	_	_	_
40	there	_	PRON	_	_	_	_	_	_
41	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	increase	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	plasma	_	NOUN	_	Number=Sing	_	_	_	_
47	renin	_	NOUN	_	Number=Sing	_	_	_	_
48	activity	_	NOUN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	>	_	PUNCT	_	_	_	_	_	_
51	37	_	NUM	_	NumType=Card	_	_	_	_
52	ng	_	NOUN	_	Number=Sing	_	_	_	_
53	/	_	PUNCT	_	_	_	_	_	_
54	ml	_	NOUN	_	Number=Sing	_	_	_	_
55	/	_	PUNCT	_	_	_	_	_	_
56	h	_	NOUN	_	Number=Sing	_	_	_	_
57	;	_	PUNCT	_	_	_	_	_	_
58	N	_	PROPN	_	Number=Sing	_	_	_	_
59	supine	_	NOUN	_	Number=Sing	_	_	_	_
60	<3	_	PUNCT	_	NumType=Card	_	_	_	_
61	)	_	PUNCT	_	_	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	active	_	ADJ	_	Degree=Pos	_	_	_	_
64	renin	_	NOUN	_	Number=Sing	_	_	_	_
65	(	_	PUNCT	_	_	_	_	_	_
66	869	_	NUM	_	NumType=Card	_	_	_	_
67	pg	_	NOUN	_	Number=Sing	_	_	_	_
68	/	_	PUNCT	_	_	_	_	_	_
69	ml	_	NOUN	_	Number=Sing	_	_	_	_
70	;	_	PUNCT	_	_	_	_	_	_
71	N	_	CCONJ	_	Number=Sing	_	_	_	_
72	supine	_	NOUN	_	Number=Sing	_	_	_	_
73	:	_	PUNCT	_	_	_	_	_	_
74	1.120	_	NUM	_	NumType=Card	_	_	_	_
75	)	_	PUNCT	_	_	_	_	_	_
76	,	_	PUNCT	_	_	_	_	_	_
77	aldosterone	_	NOUN	_	Number=Sing	_	_	_	_
78	(	_	PUNCT	_	_	_	_	_	_
79	>	_	PUNCT	_	_	_	_	_	_
80	2000	_	NUM	_	NumType=Card	_	_	_	_
81	pg	_	NOUN	_	Number=Sing	_	_	_	_
82	/	_	PUNCT	_	_	_	_	_	_
83	ml	_	NOUN	_	Number=Sing	_	_	_	_
84	;	_	PUNCT	_	_	_	_	_	_
85	N	_	PROPN	_	Number=Sing	_	_	_	_
86	supine	_	NOUN	_	Number=Sing	_	_	_	_
87	<	_	PUNCT	_	_	_	_	_	_
88	150	_	NUM	_	NumType=Card	_	_	_	_
89	)	_	PUNCT	_	_	_	_	_	_
90	and	_	CCONJ	_	_	_	_	_	_
91	plasma	_	NOUN	_	Number=Sing	_	_	_	_
92	AVP	_	NOUN	_	Number=Sing	_	_	_	_
93	(	_	PUNCT	_	_	_	_	_	_
94	20	_	NUM	_	NumType=Card	_	_	_	_
95	pmol	_	NOUN	_	Number=Sing	_	_	_	_
96	/	_	PUNCT	_	_	_	_	_	_
97	l	_	NOUN	_	Number=Sing	_	_	_	_
98	;	_	PUNCT	_	_	_	_	_	_
99	N	_	NOUN	_	Number=Sing	_	_	_	_
100	:	_	PUNCT	_	_	_	_	_	_
101	0.5	_	NUM	_	NumType=Card	_	_	_	_
102	-	_	SYM	_	_	_	_	_	_
103	2.5	_	NUM	_	NumType=Card	_	_	_	_
104	)	_	PUNCT	_	_	_	_	_	_
105	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	plasma	_	NOUN	_	Number=Sing	_	_	_	_
3	ANH	_	NOUN	_	Number=Sing	_	_	_	_
4	level	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	38	_	NUM	_	NumType=Card	_	_	_	_
7	pmol	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	l	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	N	_	PROPN	_	Number=Sing	_	_	_	_
12	supine	_	NOUN	_	Number=Sing	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	5-25	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	urinary	_	ADJ	_	Degree=Pos	_	_	_	_
3	steroidogram	_	NOUN	_	Number=Sing	_	_	_	_
4	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	highly	_	ADV	_	_	_	_	_	_
7	elevated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	tetrahydrocortisol	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	THF	_	NOUN	_	Number=Sing	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	13.3	_	NUM	_	NumType=Card	_	_	_	_
13	mg/24h	_	NOUN	_	Number=Sing	_	_	_	_
14	;	_	PUNCT	_	_	_	_	_	_
15	N	_	NOUN	_	Number=Sing	_	_	_	_
16	:	_	PUNCT	_	_	_	_	_	_
17	1.4+/-0.8	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	no	_	DET	_	_	_	_	_	_
21	increase	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	tetrahydrocortisone	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	THE	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	:	_	PUNCT	_	_	_	_	_	_
27	3.16	_	NUM	_	NumType=Card	_	_	_	_
28	mg/24h	_	NOUN	_	Number=Sing	_	_	_	_
29	;	_	PUNCT	_	_	_	_	_	_
30	N	_	NOUN	_	Number=Sing	_	_	_	_
31	:	_	PUNCT	_	_	_	_	_	_
32	2.7+/-2.0	_	NUM	_	NumType=Card	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	excretion	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	low	_	ADJ	_	Degree=Pos	_	_	_	_
39	THE	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	/	_	PUNCT	_	_	_	_	_	_
41	THF	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	0.24	_	NUM	_	NumType=Card	_	_	_	_
44	;	_	PUNCT	_	_	_	_	_	_
45	N	_	NOUN	_	Number=Sing	_	_	_	_
46	:	_	PUNCT	_	_	_	_	_	_
47	1.87+/-0.36	_	NUM	_	NumType=Card	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	alpha	_	NOUN	_	Number=Sing	_	_	_	_
51	THF	_	NOUN	_	Number=Sing	_	_	_	_
52	/	_	PUNCT	_	_	_	_	_	_
53	THF	_	NOUN	_	Number=Sing	_	_	_	_
54	(	_	PUNCT	_	_	_	_	_	_
55	0.35	_	NUM	_	NumType=Card	_	_	_	_
56	;	_	PUNCT	_	_	_	_	_	_
57	N	_	NOUN	_	Number=Sing	_	_	_	_
58	:	_	PUNCT	_	_	_	_	_	_
59	0.92+/-0.42	_	NUM	_	NumType=Card	_	_	_	_
60	)	_	PUNCT	_	_	_	_	_	_
61	ratios	_	NOUN	_	Number=Plur	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	number	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	mineralocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
5	receptors	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
13	normal	_	ADJ	_	Degree=Pos	_	_	_	_
14	range	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	age	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	while	_	SCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	number	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
23	receptors	_	NOUN	_	Number=Plur	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Small	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	bowel	_	NOUN	_	Number=Sing	_	_	_	_
4	resection	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	ileostomized	_	ADJ	_	Degree=Pos	_	_	_	_
7	patients	_	NOUN	_	Number=Plur	_	_	_	_
8	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	excessive	_	ADJ	_	Degree=Pos	_	_	_	_
10	fecal	_	ADJ	_	Degree=Pos	_	_	_	_
11	sodium	_	NOUN	_	Number=Sing	_	_	_	_
12	losses	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	results	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
17	sodium	_	NOUN	_	Number=Sing	_	_	_	_
18	depletion	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	contraction	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	plasma	_	NOUN	_	Number=Sing	_	_	_	_
24	volume	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	severe	_	ADJ	_	Degree=Pos	_	_	_	_
27	secondary	_	ADJ	_	Degree=Pos	_	_	_	_
28	hyperaldosteronism	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Nevertheless	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	hyperaldosteronism	_	NOUN	_	Number=Sing	_	_	_	_
5	may	_	AUX	_	VerbForm=Fin	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	hyponatremia	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	hyperkalemia	_	NOUN	_	Number=Sing	_	_	_	_
12	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	PHA	_	NOUN	_	Number=Sing	_	_	_	_
14	related	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	major	_	ADJ	_	Degree=Pos	_	_	_	_
18	importance	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	colon	_	NOUN	_	Number=Sing	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	absorption	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	sodium	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	case	_	NOUN	_	Number=Sing	_	_	_	_
6	report	_	NOUN	_	Number=Sing	_	_	_	_
7	emphasizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	1	_	X	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	possibility	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	acquired	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	PHA	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	severe	_	ADJ	_	Degree=Pos	_	_	_	_
20	hyperkalemia	_	NOUN	_	Number=Sing	_	_	_	_
21	after	_	ADP	_	_	_	_	_	_
22	resection	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	ileum	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	colon	_	NOUN	_	Number=Sing	_	_	_	_
28	responding	_	VERB	_	VerbForm=Ger	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	oral	_	ADJ	_	Degree=Pos	_	_	_	_
31	salt	_	NOUN	_	Number=Sing	_	_	_	_
32	supplementation	_	NOUN	_	Number=Sing	_	_	_	_
33	;	_	PUNCT	_	_	_	_	_	_
34	2	_	X	_	_	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	major	_	ADJ	_	Degree=Pos	_	_	_	_
38	increase	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	AVP	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	small	_	ADJ	_	Degree=Pos	_	_	_	_
44	increase	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	ANH	_	PROPN	_	Number=Sing	_	_	_	_
47	;	_	PUNCT	_	_	_	_	_	_
48	3	_	X	_	_	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	strong	_	ADJ	_	Degree=Pos	_	_	_	_
52	increase	_	NOUN	_	Number=Sing	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	urinary	_	ADJ	_	Degree=Pos	_	_	_	_
55	THF	_	NOUN	_	Number=Sing	_	_	_	_
56	with	_	ADP	_	_	_	_	_	_
57	low	_	ADJ	_	Degree=Pos	_	_	_	_
58	THE	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
59	/	_	PUNCT	_	_	_	_	_	_
60	THF	_	NOUN	_	Number=Sing	_	_	_	_
61	and	_	CCONJ	_	_	_	_	_	_
62	alpha	_	NOUN	_	Number=Sing	_	_	_	_
63	THF	_	NOUN	_	Number=Sing	_	_	_	_
64	/	_	PUNCT	_	_	_	_	_	_
65	THF	_	NOUN	_	Number=Sing	_	_	_	_
66	ratios	_	NOUN	_	Number=Plur	_	_	_	_
67	;	_	PUNCT	_	_	_	_	_	_
68	4	_	X	_	_	_	_	_	_
69	)	_	PUNCT	_	_	_	_	_	_
70	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
71	normal	_	ADJ	_	Degree=Pos	_	_	_	_
72	number	_	NOUN	_	Number=Sing	_	_	_	_
73	of	_	ADP	_	_	_	_	_	_
74	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
75	mineralocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
76	receptors	_	NOUN	_	Number=Plur	_	_	_	_
77	outside	_	ADP	_	_	_	_	_	_
78	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
79	acute	_	ADJ	_	Degree=Pos	_	_	_	_
80	episode	_	NOUN	_	Number=Sing	_	_	_	_
81	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003169	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Genetic	_	ADJ	_	Degree=Pos	_	_	_	_
2	evidence	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	additional	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	signal	_	NOUN	_	Number=Sing	_	_	_	_
13	transduction	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Erythropoietin	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	EPO	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	EPOR	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	development	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	mature	_	ADJ	_	Degree=Pos	_	_	_	_
18	erythrocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	ligand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	EPOR	_	NOUN	_	Number=Sing	_	_	_	_
8	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	variety	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
13	pathways	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	ADV	_	PronType=Rel	_	_	_	_
15	ultimately	_	ADV	_	_	_	_	_	_
16	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	survival	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
3	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
4	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	principal	_	ADJ	_	Degree=Pos	_	_	_	_
9	EPO	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	vivo	_	NOUN	_	Number=Sing	_	_	_	_
16	due	_	ADP	_	_	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	EPOR	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	many	_	ADJ	_	Degree=Pos	_	_	_	_
26	growth	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	lines	_	NOUN	_	Number=Plur	_	_	_	_
32	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	EPOR	_	NOUN	_	Number=Sing	_	_	_	_
35	can	_	AUX	_	VerbForm=Fin	_	_	_	_
36	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	EPO	_	NOUN	_	Number=Sing	_	_	_	_
39	by	_	SCONJ	_	_	_	_	_	_
40	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
41	many	_	ADJ	_	Degree=Pos	_	_	_	_
42	or	_	CCONJ	_	_	_	_	_	_
43	all	_	DET	_	_	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
46	pathways	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	context	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	[	_	PUNCT	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2]-	_	PUNCT	_	_	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	HT	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	line	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	EPO	_	NOUN	_	Number=Sing	_	_	_	_
31	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	EPOR	_	NOUN	_	Number=Sing	_	_	_	_
35	fails	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	support	_	VERB	_	VerbForm=Inf	_	_	_	_
38	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
39	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	STAT	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	5	_	NUM	_	NumType=Card	_	_	_	_
44	induction	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	or	_	CCONJ	_	_	_	_	_	_
47	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
48	activation	_	NOUN	_	Number=Sing	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	despite	_	ADP	_	_	_	_	_	_
51	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
52	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
53	of	_	ADP	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	EPOR	_	NOUN	_	Number=Sing	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	JAK2	_	NOUN	_	Number=Sing	_	_	_	_
58	and	_	CCONJ	_	_	_	_	_	_
59	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
60	of	_	ADP	_	_	_	_	_	_
61	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
62	after	_	ADP	_	_	_	_	_	_
63	withdrawal	_	NOUN	_	Number=Sing	_	_	_	_
64	of	_	ADP	_	_	_	_	_	_
65	IL	_	PROPN	_	Number=Sing	_	_	_	_
66	-	_	PUNCT	_	_	_	_	_	_
67	2	_	NUM	_	NumType=Card	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	when	_	ADV	_	PronType=Int	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	fused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	HT	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	EPOR	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	Ba	_	PROPN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	F3	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	complementation	_	NOUN	_	Number=Sing	_	_	_	_
21	assay	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	hybridomas	_	NOUN	_	Number=Plur	_	_	_	_
26	proliferated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	potently	_	ADV	_	_	_	_	_	_
29	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	STAT	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	5	_	NUM	_	NumType=Card	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	response	_	NOUN	_	Number=Sing	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	EPO	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	unidentified	_	ADJ	_	Degree=Pos	_	_	_	_
7	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	needed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	signaling	_	VERB	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	EPOR	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Ba	_	PROPN	_	Number=Sing	_	_	_	_
4	/	_	PUNCT	_	_	_	_	_	_
5	F3	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	apparently	_	ADV	_	_	_	_	_	_
8	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	s	_	X	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	somatic	_	ADJ	_	Degree=Pos	_	_	_	_
16	fusions	_	NOUN	_	Number=Plur	_	_	_	_
17	can	_	AUX	_	VerbForm=Fin	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	therefore	_	ADV	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	confer	_	VERB	_	VerbForm=Inf	_	_	_	_
22	EPO	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	HT	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	that	_	PRON	_	PronType=Rel	_	_	_	_
31	lack	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003171	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	7	_	NUM	_	NumType=Card	_	_	_	_
4	can	_	AUX	_	VerbForm=Fin	_	_	_	_
5	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Jak	_	PROPN	_	Number=Sing	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	Jak	_	PROPN	_	Number=Sing	_	_	_	_
13	3	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	STAT	_	NOUN	_	Number=Sing	_	_	_	_
16	5	_	NUM	_	NumType=Card	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	murine	_	ADJ	_	Number=Sing	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Janus	_	PROPN	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	kinases	_	NOUN	_	Number=Plur	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	Jak	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	STAT	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	signal	_	NOUN	_	Number=Sing	_	_	_	_
15	transducer	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	activator	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	recently	_	ADV	_	_	_	_	_	_
24	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
25	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	signal	_	ADJ	_	Number=Sing	_	_	_	_
29	transduction	_	NOUN	_	Number=Sing	_	_	_	_
30	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	several	_	ADJ	_	Degree=Pos	_	_	_	_
33	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	7	_	NUM	_	NumType=Card	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	dose	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
15	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Jak	_	PROPN	_	Number=Sing	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	Jak	_	PROPN	_	Number=Sing	_	_	_	_
21	3	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	concomitantly	_	ADV	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	DNA	_	NOUN	_	Number=Sing	_	_	_	_
30	binding	_	VERB	_	Number=Sing	_	_	_	_
31	activity	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
34	STAT	_	NOUN	_	Number=Sing	_	_	_	_
35	proteins	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	STAT	_	PROPN	_	Number=Sing	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	utilized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	7	_	NUM	_	NumType=Card	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	identical	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	could	_	AUX	_	VerbForm=Fin	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	various	_	ADJ	_	Degree=Pos	_	_	_	_
24	STAT	_	NOUN	_	Number=Sing	_	_	_	_
25	5	_	NUM	_	NumType=Card	_	_	_	_
26	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	Jak	_	PROPN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	STAT	_	NOUN	_	Number=Sing	_	_	_	_
14	5	_	NUM	_	NumType=Card	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	strongly	_	ADV	_	_	_	_	_	_
17	correlated	_	VERB	_	Degree=Pos	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	growth	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
23	effects	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	7	_	NUM	_	NumType=Card	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
30	that	_	SCONJ	_	_	_	_	_	_
31	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
32	signal	_	NOUN	_	Number=Sing	_	_	_	_
33	transduction	_	NOUN	_	Number=Sing	_	_	_	_
34	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
35	may	_	AUX	_	VerbForm=Fin	_	_	_	_
36	play	_	VERB	_	VerbForm=Inf	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	key	_	ADJ	_	Degree=Pos	_	_	_	_
39	role	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	7	_	NUM	_	NumType=Card	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003172	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tyrosine	_	PROPN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	activities	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	CD40	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	undergo	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	long	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	term	_	NOUN	_	Number=Sing	_	_	_	_
11	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
12	when	_	ADV	_	PronType=Int	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	CD40	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	surface	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nature	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	CD40	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	signals	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	proliferating	_	VERB	_	VerbForm=Ger	_	_	_	_
10	fresh	_	ADJ	_	Degree=Pos	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	Barr	_	PROPN	_	Number=Sing	_	_	_	_
15	virus	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	negative	_	ADJ	_	Degree=Pos	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	currently	_	ADV	_	_	_	_	_	_
22	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	CD40	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	B	_	NOUN	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	culture	_	NOUN	_	Number=Sing	_	_	_	_
12	system	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	role	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	different	_	ADJ	_	Degree=Pos	_	_	_	_
21	signal	_	NOUN	_	Number=Sing	_	_	_	_
22	transduction	_	NOUN	_	Number=Sing	_	_	_	_
23	elements	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	PROPN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	C	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	PKC	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	depletion	_	NOUN	_	Number=Sing	_	_	_	_
8	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	long	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	term	_	NOUN	_	Number=Sing	_	_	_	_
14	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
15	12	_	NUM	_	NumType=Card	_	_	_	_
16	myristate	_	NOUN	_	Number=Sing	_	_	_	_
17	13	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	acetate	_	ADJ	_	Degree=Pos	_	_	_	_
20	treatment	_	NOUN	_	Number=Sing	_	_	_	_
21	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	weak	_	ADJ	_	Degree=Pos	_	_	_	_
23	effects	_	NOUN	_	Number=Plur	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Rather	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	directly	_	ADV	_	_	_	_	_	_
10	involved	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	SCONJ	_	_	_	_	_	_
12	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	CD40	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
16	signals	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	use	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	PTK	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
14	herbimycin	_	NOUN	_	Number=Sing	_	_	_	_
15	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	dramatically	_	ADV	_	_	_	_	_	_
17	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
19	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
20	without	_	SCONJ	_	_	_	_	_	_
21	altering	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
28	virus	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	long	_	ADJ	_	Degree=Pos	_	_	_	_
32	terminal	_	NOUN	_	Number=Sing	_	_	_	_
33	repeat	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	HIV	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	LTR	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	largely	_	ADV	_	_	_	_	_	_
44	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
45	on	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	binding	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
50	factor	_	NOUN	_	Number=Sing	_	_	_	_
51	kappa	_	NOUN	_	Number=Sing	_	_	_	_
52	B	_	NOUN	_	Number=Sing	_	_	_	_
53	(	_	PUNCT	_	_	_	_	_	_
54	NF	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	kappa	_	NOUN	_	Number=Sing	_	_	_	_
57	B	_	NOUN	_	Number=Sing	_	_	_	_
58	)	_	PUNCT	_	_	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
12	H-89	_	NOUN	_	Number=Sing	_	_	_	_
13	totally	_	ADV	_	_	_	_	_	_
14	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	HIV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	LTR	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	concentration	_	NOUN	_	Number=Sing	_	_	_	_
23	as	_	ADV	_	_	_	_	_	_
24	low	_	ADJ	_	Degree=Pos	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	100	_	NUM	_	NumType=Card	_	_	_	_
27	nM	_	NOUN	_	Number=Sing	_	_	_	_
28	without	_	SCONJ	_	_	_	_	_	_
29	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
30	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
31	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	supershift	_	NOUN	_	Number=Sing	_	_	_	_
10	assay	_	VERB	_	Number=Sing	_	_	_	_
11	using	_	VERB	_	VerbForm=Ger	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	sequence	_	NOUN	_	Number=Sing	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	kappa	_	PROPN	_	Number=Sing	_	_	_	_
22	light	_	NOUN	_	Number=Sing	_	_	_	_
23	chain	_	NOUN	_	Number=Sing	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	probe	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	both	_	CCONJ	_	_	_	_	_	_
31	p65	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	RelA	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	c-Rel	_	NOUN	_	Number=Plur	_	_	_	_
37	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	present	_	ADJ	_	Degree=Pos	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	CD40	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	B	_	NOUN	_	Number=Sing	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	PKC	_	PROPN	_	Number=Sing	_	_	_	_
3	depletion	_	NOUN	_	Number=Sing	_	_	_	_
4	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	level	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	treatment	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	B	_	NOUN	_	Degree=Pos	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	H-89	_	NUM	_	NumType=Card	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	herbimycin	_	NOUN	_	Number=Sing	_	_	_	_
22	A	_	PROPN	_	Definite=Ind|PronType=Art	_	_	_	_
23	provoked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	decrease	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	level	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	establish	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	importance	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	different	_	ADJ	_	Degree=Pos	_	_	_	_
8	signal	_	NOUN	_	Number=Sing	_	_	_	_
9	transducing	_	NOUN	_	Number=Sing	_	_	_	_
10	pathways	_	NOUN	_	Number=Plur	_	_	_	_
11	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	CD40	_	PROPN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003176	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Effects	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	25	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_

1	D3	_	VERB	_	Number=Sing	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	chronic	_	ADJ	_	Number=Sing	_	_	_	_
6	myelogenous	_	ADJ	_	Degree=Pos	_	_	_	_
7	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	line	_	NOUN	_	Number=Sing	_	_	_	_
10	RWLeu	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	25	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
10	D3	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	VD3	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	macromolecular	_	ADJ	_	Degree=Pos	_	_	_	_
21	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	new	_	ADJ	_	Degree=Pos	_	_	_	_
25	Philadelphia	_	PROPN	_	Number=Sing	_	_	_	_
26	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	positive	_	ADJ	_	Degree=Pos	_	_	_	_
29	chronic	_	ADJ	_	Number=Sing	_	_	_	_
30	myelogenous	_	ADJ	_	Degree=Pos	_	_	_	_
31	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	line	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	RWLeu	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	4	_	NUM	_	NumType=Card	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	[	_	PUNCT	_	_	_	_	_	_
4	3H	_	NOUN	_	Number=Sing	_	_	_	_
5	]	_	PUNCT	_	_	_	_	_	_
6	VD3	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	saturable	_	ADJ	_	Degree=Pos	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	approximately	_	ADV	_	_	_	_	_	_
12	2000	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	3000	_	NUM	_	NumType=Card	_	_	_	_
15	sites	_	NOUN	_	Number=Plur	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	half	_	ADJ	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
25	at	_	ADP	_	_	_	_	_	_
26	0.21-0.33	_	NUM	_	NumType=Card	_	_	_	_
27	nM	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	RWLeu	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	4	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	VD3	_	PROPN	_	Number=Sing	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	24R	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	hydroxylase	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	marker	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	vitamin	_	NOUN	_	Number=Sing	_	_	_	_

1	D3	_	VERB	_	Number=Sing	_	_	_	_
2	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	many	_	ADJ	_	Degree=Pos	_	_	_	_
5	tissues	_	NOUN	_	Number=Plur	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	Exposure	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	RWLeu	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	4	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	VD3	_	PROPN	_	Number=Sing	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	50	_	NUM	_	NumType=Card	_	_	_	_
18	%	_	SYM	_	Number=Sing	_	_	_	_
19	effective	_	ADJ	_	Degree=Pos	_	_	_	_
20	dose	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	3.5	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	10	_	NUM	_	NumType=Card	_	_	_	_
25	nM	_	NOUN	_	Number=Sing	_	_	_	_
26	within	_	ADP	_	_	_	_	_	_
27	72	_	NUM	_	NumType=Card	_	_	_	_
28	h	_	NOUN	_	Number=Plur	_	_	_	_
29	;	_	PUNCT	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	addition	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	protein	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	RNA	_	PROPN	_	Number=Sing	_	_	_	_
36	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
37	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	VD3	_	NOUN	_	Number=Sing	_	_	_	_
41	treatment	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Exposure	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	RWLeu	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	4	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	nM	_	NOUN	_	Number=Sing	_	_	_	_
10	VD3	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	72	_	NUM	_	NumType=Card	_	_	_	_
13	h	_	NOUN	_	Number=Plur	_	_	_	_
14	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	50	_	NUM	_	NumType=Card	_	_	_	_
16	%	_	SYM	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	into	_	ADP	_	_	_	_	_	_
23	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
26	type	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	as	_	SCONJ	_	_	_	_	_	_
29	judged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	nitroblue	_	ADJ	_	Number=Sing	_	_	_	_
32	tetrazolium	_	NOUN	_	Number=Sing	_	_	_	_
33	staining	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	adherence	_	NOUN	_	Number=Sing	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	plastic	_	NOUN	_	Degree=Pos	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Progressive	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	surface	_	NOUN	_	Number=Sing	_	_	_	_
6	maturation	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	antigens	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
15	lineage	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	RWLeu	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	4	_	NUM	_	NumType=Card	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	VD3	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	24	_	NUM	_	NumType=Card	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	72	_	NUM	_	NumType=Card	_	_	_	_
31	h	_	NOUN	_	Number=Plur	_	_	_	_
32	at	_	ADP	_	_	_	_	_	_
33	doses	_	NOUN	_	Number=Plur	_	_	_	_
34	that	_	PRON	_	PronType=Rel	_	_	_	_
35	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
37	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	c-myc	_	PROPN	_	Number=Sing	_	_	_	_
2	RNA	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	constitutively	_	ADV	_	_	_	_	_	_
7	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	RWLeu	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	after	_	ADP	_	_	_	_	_	_
16	0.5	_	NUM	_	NumType=Card	_	_	_	_
17	h	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	50	_	NUM	_	NumType=Card	_	_	_	_
22	nM	_	NOUN	_	Number=Sing	_	_	_	_
23	VD3	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	then	_	ADV	_	PronType=Dem	_	_	_	_
26	rapidly	_	ADV	_	_	_	_	_	_
27	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	barely	_	ADV	_	_	_	_	_	_
30	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
31	levels	_	NOUN	_	Number=Plur	_	_	_	_
32	after	_	ADP	_	_	_	_	_	_
33	4	_	NUM	_	NumType=Card	_	_	_	_
34	h	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	treatment	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	vitro	_	NOUN	_	Number=Sing	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	p210bcr	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	abl	_	NOUN	_	Number=Sing	_	_	_	_
15	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
16	product	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	approximately	_	ADV	_	_	_	_	_	_
20	50	_	NUM	_	NumType=Card	_	_	_	_
21	%	_	SYM	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	VD3	_	NOUN	_	Number=Sing	_	_	_	_
24	treatment	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	ADP	_	_	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	presence	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	functional	_	ADJ	_	Degree=Pos	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	effector	_	NOUN	_	Number=Sing	_	_	_	_
11	system	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	VD3	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
16	biological	_	ADJ	_	Degree=Pos	_	_	_	_
17	responses	_	NOUN	_	Number=Plur	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	hormone	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	unique	_	ADJ	_	Degree=Pos	_	_	_	_
27	model	_	NOUN	_	Number=Sing	_	_	_	_
28	system	_	NOUN	_	Number=Sing	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	which	_	PRON	_	PronType=Rel	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	probe	_	VERB	_	VerbForm=Inf	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	specific	_	ADJ	_	Degree=Pos	_	_	_	_
35	effects	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	VD3	_	NOUN	_	Number=Sing	_	_	_	_
38	on	_	ADP	_	_	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	growth	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	chronic	_	ADJ	_	Number=Sing	_	_	_	_
45	myelogenous	_	ADJ	_	Degree=Pos	_	_	_	_
46	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003178	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	cycle	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	initiation	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	lineage	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	abrogation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	GATA	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	pure	_	ADJ	_	Degree=Pos	_	_	_	_
18	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
19	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
20	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	programmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	/	_	PUNCT	_	_	_	_	_	_
5	repression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	early	_	ADJ	_	Degree=Pos	_	_	_	_
11	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	yet	_	ADV	_	_	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	explored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	GATA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	normal	_	ADJ	_	Degree=Pos	_	_	_	_
13	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
14	development	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	SCONJ	_	_	_	_	_	_
22	maturing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	GATA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	early	_	ADJ	_	Degree=Pos	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	adult	_	NOUN	_	Number=Sing	_	_	_	_
11	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	using	_	VERB	_	VerbForm=Ger	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	vitro	_	NOUN	_	Number=Sing	_	_	_	_
17	system	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	"	_	PUNCT	_	_	_	_	_	_
21	pure	_	ADJ	_	Degree=Pos	_	_	_	_
22	"	_	PUNCT	_	_	_	_	_	_
23	early	_	ADJ	_	Degree=Pos	_	_	_	_
24	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
25	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
26	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	gradual	_	ADJ	_	Degree=Pos	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	synchronized	_	VERB	_	Degree=Pos	_	_	_	_
32	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
33	selectively	_	ADV	_	_	_	_	_	_
34	along	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
41	pathway	_	NOUN	_	Number=Sing	_	_	_	_
42	by	_	ADP	_	_	_	_	_	_
43	differential	_	ADJ	_	Degree=Pos	_	_	_	_
44	treatment	_	NOUN	_	Number=Sing	_	_	_	_
45	with	_	ADP	_	_	_	_	_	_
46	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
47	growth	_	NOUN	_	Number=Sing	_	_	_	_
48	factors	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GATA	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	though	_	SCONJ	_	_	_	_	_	_
8	virtually	_	ADV	_	_	_	_	_	_
9	silent	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	quiescent	_	ADJ	_	Degree=Pos	_	_	_	_
12	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	after	_	ADP	_	_	_	_	_	_
17	entrance	_	NOUN	_	Number=Sing	_	_	_	_
18	into	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	cycle	_	NOUN	_	Number=Sing	_	_	_	_
22	upon	_	ADP	_	_	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
26	growth	_	NOUN	_	Number=Sing	_	_	_	_
27	factors	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Subsequently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	along	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
8	pathway	_	NOUN	_	Number=Sing	_	_	_	_
9	contrasts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	abrupt	_	ADJ	_	Degree=Pos	_	_	_	_
13	downregulation	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
19	lineage	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	microenvironment	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	step	_	NOUN	_	Number=Sing	_	_	_	_
12	model	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	GATA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	SCONJ	_	_	_	_	_	_
19	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
21	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	i	_	X	_	_	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	cycle	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
30	initiation	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	ii	_	X	_	_	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	lineage	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
38	maintenance	_	NOUN	_	Number=Sing	_	_	_	_
39	or	_	CCONJ	_	_	_	_	_	_
40	suppression	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Hypothetically	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	/	_	PUNCT	_	_	_	_	_	_
5	off	_	ADP	_	Degree=Pos	_	_	_	_
6	switches	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	lineage	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	transactivators	_	NOUN	_	Number=Plur	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	underlie	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	binary	_	ADJ	_	Degree=Pos	_	_	_	_
16	fate	_	NOUN	_	Number=Sing	_	_	_	_
17	decisions	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
20	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003184	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	envelope	_	NOUN	_	Number=Sing	_	_	_	_
5	glycoproteins	_	NOUN	_	Number=Plur	_	_	_	_
6	induce	_	VERB	_	Degree=Pos	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	CD4	_	PROPN	_	Number=Sing	_	_	_	_
15	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	[	_	PUNCT	_	_	_	_	_	_
4	published	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	erratum	_	NOUN	_	Number=Sing	_	_	_	_
6	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	J	_	PROPN	_	Number=Sing	_	_	_	_
9	Biol	_	PROPN	_	Number=Sing	_	_	_	_
10	Chem	_	PROPN	_	Number=Sing	_	_	_	_
11	1995	_	NUM	_	NumType=Card	_	_	_	_
12	Dec	_	PROPN	_	Number=Sing	_	_	_	_
13	1;270	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	48	_	NUM	_	NumType=Card	_	_	_	_
16	):29038	_	PUNCT	_	_	_	_	_	_
17	]	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CD4	_	PROPN	_	Number=Sing	_	_	_	_
4	positive	_	ADJ	_	Degree=Pos	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	requirement	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	entry	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
21	HIV	_	NOUN	_	Number=Sing	_	_	_	_
22	replication	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	progression	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	Utilizing	_	VERB	_	VerbForm=Ger	_	_	_	_
30	CD4	_	PROPN	_	Number=Sing	_	_	_	_
31	positive	_	ADJ	_	Degree=Pos	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	lines	_	NOUN	_	Number=Plur	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	T	_	NOUN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	from	_	ADP	_	_	_	_	_	_
40	normal	_	ADJ	_	Degree=Pos	_	_	_	_
41	individuals	_	NOUN	_	Number=Plur	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
44	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
45	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	that	_	SCONJ	_	_	_	_	_	_
47	native	_	ADJ	_	Degree=Pos	_	_	_	_
48	envelope	_	NOUN	_	Number=Sing	_	_	_	_
49	glycoproteins	_	NOUN	_	Number=Plur	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	HIV	_	NOUN	_	Number=Sing	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	gp	_	NOUN	_	Number=Sing	_	_	_	_
54	160	_	NUM	_	NumType=Card	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	can	_	AUX	_	VerbForm=Fin	_	_	_	_
57	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
58	activation	_	NOUN	_	Number=Sing	_	_	_	_
59	of	_	ADP	_	_	_	_	_	_
60	transcription	_	NOUN	_	Number=Sing	_	_	_	_
61	factor	_	NOUN	_	Number=Sing	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
64	protein	_	NOUN	_	Number=Sing	_	_	_	_
65	-	_	PUNCT	_	_	_	_	_	_
66	1	_	NUM	_	NumType=Card	_	_	_	_
67	(	_	PUNCT	_	_	_	_	_	_
68	AP	_	NOUN	_	Number=Sing	_	_	_	_
69	-	_	PUNCT	_	_	_	_	_	_
70	1	_	NUM	_	NumType=Card	_	_	_	_
71	)	_	PUNCT	_	_	_	_	_	_
72	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	gp160	_	NOUN	_	Number=Sing	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	CD4	_	PROPN	_	Number=Sing	_	_	_	_
11	molecule	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	since	_	ADP	_	_	_	_	_	_
14	treatment	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	gp160	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
19	CD4	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	IgG	_	PROPN	_	Number=Sing	_	_	_	_
22	abrogates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	CD4	_	PROPN	_	Number=Sing	_	_	_	_
28	negative	_	ADJ	_	Degree=Pos	_	_	_	_
29	T	_	NOUN	_	Number=Sing	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	lines	_	NOUN	_	Number=Plur	_	_	_	_
32	fail	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	be	_	AUX	_	VerbForm=Inf	_	_	_	_
35	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	gp160	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	gp	_	NOUN	_	Number=Sing	_	_	_	_
5	160	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	extracts	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
12	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	Fos	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	Jun	_	PROPN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	comprised	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	members	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
30	family	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	gp160	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	AP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	complex	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	upon	_	ADP	_	_	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
14	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	independent	_	ADJ	_	Degree=Pos	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	C	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	unaffected	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	calcium	_	NOUN	_	Number=Sing	_	_	_	_
20	channel	_	NOUN	_	Number=Sing	_	_	_	_
21	blocker	_	NOUN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	cyclosporine	_	NOUN	_	Number=Sing	_	_	_	_
24	A	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	gp160	_	VERB	_	Number=Sing	_	_	_	_
3	treatment	_	NOUN	_	Number=Sing	_	_	_	_
4	adversely	_	ADV	_	_	_	_	_	_
5	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	functional	_	ADJ	_	Degree=Pos	_	_	_	_
8	capabilities	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	:	_	PUNCT	_	_	_	_	_	_
13	pre	_	X	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	treatment	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	CD4	_	NOUN	_	Number=Sing	_	_	_	_
18	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	gp160	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	h	_	NOUN	_	Number=Sing	_	_	_	_
8	at	_	ADP	_	_	_	_	_	_
9	37	_	NUM	_	NumType=Card	_	_	_	_
10	degrees	_	NOUN	_	Number=Plur	_	_	_	_
11	C	_	PROPN	_	Number=Sing	_	_	_	_
12	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	anti-CD3	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	secretion	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Effects	_	NOUN	_	Number=Plur	_	_	_	_
2	similar	_	ADJ	_	Degree=Pos	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	gp160	_	NOUN	_	Number=Sing	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	anti-CD4	_	PROPN	_	Number=Sing	_	_	_	_
9	mAb	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	aberrant	_	NOUN	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	AP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	gp160	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	CD4	_	PROPN	_	Number=Sing	_	_	_	_
12	positive	_	ADJ	_	Degree=Pos	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	could	_	AUX	_	VerbForm=Fin	_	_	_	_
16	result	_	VERB	_	VerbForm=Inf	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	up	_	ADP	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	regulation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
23	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	AP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	sites	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	e.g.	_	ADV	_	_	_	_	_	_
30	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	3	_	NUM	_	NumType=Card	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
35	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
36	colony	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
39	factor	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	concurrently	_	ADV	_	_	_	_	_	_
43	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
44	to	_	ADP	_	_	_	_	_	_
45	T	_	NUM	_	Number=Sing	_	_	_	_
46	cell	_	NOUN	_	Number=Sing	_	_	_	_
47	unresponsiveness	_	NOUN	_	Number=Sing	_	_	_	_
48	by	_	SCONJ	_	_	_	_	_	_
49	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
50	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	2	_	NUM	_	NumType=Card	_	_	_	_
53	secretion	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003190	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	[	_	PUNCT	_	_	_	_	_	_
2	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	role	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
6	receptors	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	HLA	_	PROPN	_	Number=Sing	_	_	_	_
9	antigens	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	Cushing	_	PROPN	_	Number=Sing	_	_	_	_
15	's	_	PART	_	_	_	_	_	_
16	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
17	]	_	PUNCT	_	_	_	_	_	_

1	Lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
5	receptors	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	114	_	NUM	_	NumType=Card	_	_	_	_
10	patients	_	NOUN	_	Number=Plur	_	_	_	_
11	suffering	_	VERB	_	VerbForm=Ger	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	Icenko	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	Cushing	_	PROPN	_	Number=Sing	_	_	_	_
16	's	_	PART	_	_	_	_	_	_
17	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Incidence	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HLA	_	PROPN	_	Number=Sing	_	_	_	_
4	antigens	_	NOUN	_	Number=Plur	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	94	_	NUM	_	NumType=Card	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	significant	_	ADJ	_	Degree=Pos	_	_	_	_
3	rise	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	A10	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	B27	_	NOUN	_	Number=Sing	_	_	_	_
8	antigen	_	NOUN	_	Number=Sing	_	_	_	_
9	incidence	_	NOUN	_	Number=Sing	_	_	_	_
10	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	normal	_	ADJ	_	Degree=Pos	_	_	_	_
15	subjects	_	NOUN	_	Number=Plur	_	_	_	_
16	allows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
18	antigens	_	NOUN	_	Number=Plur	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	considered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
23	markers	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	Icenko	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	Cushing	_	PROPN	_	Number=Sing	_	_	_	_
28	's	_	PART	_	_	_	_	_	_
29	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
5	receptors	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	patients	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
13	than	_	ADP	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	normal	_	ADJ	_	Degree=Pos	_	_	_	_
16	subjects	_	NOUN	_	Number=Plur	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	active	_	ADJ	_	Degree=Pos	_	_	_	_
21	stage	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	disease	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	following	_	VERB	_	VerbForm=Ger	_	_	_	_
27	bilateral	_	ADJ	_	Degree=Pos	_	_	_	_
28	total	_	ADJ	_	Degree=Pos	_	_	_	_
29	adrenalectomy	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	patients	_	NOUN	_	Number=Plur	_	_	_	_
3	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
4	B27	_	PROPN	_	Number=Sing	_	_	_	_
5	antigen	_	NOUN	_	Number=Sing	_	_	_	_
6	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
10	under	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	such	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	patients	_	NOUN	_	Number=Sing	_	_	_	_
17	free	_	ADJ	_	Degree=Pos	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	antigen	_	ADJ	_	Number=Sing	_	_	_	_
21	carriage	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Antigen	_	PROPN	_	Number=Sing	_	_	_	_
2	B27	_	PROPN	_	Number=Sing	_	_	_	_
3	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	cause	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
13	receptors	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	blood	_	NOUN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003197	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	Hodgkin	_	PROPN	_	Number=Sing	_	_	_	_
7	's	_	PART	_	_	_	_	_	_
8	disease	_	NOUN	_	Number=Sing	_	_	_	_
9	derives	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	post	_	X	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	germinal	_	ADJ	_	Number=Sing	_	_	_	_
14	center	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	Hodgkin	_	PROPN	_	Number=Sing	_	_	_	_
7	's	_	PART	_	_	_	_	_	_
8	disease	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	HIV	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	HD	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	displays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	several	_	ADJ	_	Degree=Pos	_	_	_	_
16	peculiarities	_	NOUN	_	Number=Plur	_	_	_	_
17	when	_	ADV	_	PronType=Int	_	_	_	_
18	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	HD	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	general	_	ADJ	_	Degree=Pos	_	_	_	_
24	population	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
2	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	overrepresentation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	clinically	_	ADV	_	_	_	_	_	_
6	aggressive	_	ADJ	_	Degree=Pos	_	_	_	_
7	histologic	_	ADJ	_	Degree=Pos	_	_	_	_
8	types	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	frequent	_	ADJ	_	Degree=Pos	_	_	_	_
11	infection	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Reed	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	Sternberg	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	RS	_	X	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	Barr	_	PROPN	_	Number=Sing	_	_	_	_
24	virus	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	EBV	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	histogenesis	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	HD	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	general	_	ADJ	_	Degree=Pos	_	_	_	_
14	population	_	NOUN	_	Number=Sing	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	SCONJ	_	_	_	_	_	_
19	monitoring	_	VERB	_	VerbForm=Ger	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	pattern	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	BCL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	6	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	germinal	_	ADJ	_	Number=Sing	_	_	_	_
34	center	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	GC	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	B	_	X	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	CD138	_	NOUN	_	Number=Sing	_	_	_	_
44	/	_	PUNCT	_	_	_	_	_	_
45	syndecan	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	syn	_	NOUN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	1	_	NUM	_	NumType=Card	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
55	proteoglycan	_	NOUN	_	Number=Sing	_	_	_	_
56	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
57	with	_	ADP	_	_	_	_	_	_
58	post	_	NOUN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	GC	_	NOUN	_	Number=Sing	_	_	_	_
61	,	_	PUNCT	_	_	_	_	_	_
62	terminal	_	NOUN	_	Number=Sing	_	_	_	_
63	B	_	NOUN	_	Number=Sing	_	_	_	_
64	-	_	PUNCT	_	_	_	_	_	_
65	cell	_	NOUN	_	Number=Sing	_	_	_	_
66	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	applied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	markers	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	study	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	HD	_	NOUN	_	Number=Sing	_	_	_	_
18	histogenesis	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	correlated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	status	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	virologic	_	ADJ	_	Degree=Pos	_	_	_	_
27	features	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	disease	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	RS	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	all	_	DET	_	_	_	_	_	_
9	histologic	_	ADJ	_	Degree=Pos	_	_	_	_
10	categories	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	HIV	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	HD	_	NOUN	_	Number=Sing	_	_	_	_
15	consistently	_	ADV	_	_	_	_	_	_
16	display	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	BCL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	6(-)	_	NOUN	_	NumType=Card	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	syn-1	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	+	_	SYM	_	_	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	thus	_	ADV	_	_	_	_	_	_
29	reflect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	post	_	X	_	_	_	_	_	_
31	-GC	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	BCL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	6(-)	_	NOUN	_	NumType=Card	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	syn-1	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	+)	_	SYM	_	_	_	_	_	_
9	RS	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	HIV	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	HD	_	NOUN	_	Number=Sing	_	_	_	_
15	express	_	ADJ	_	Number=Sing	_	_	_	_
16	CD40	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	surrounded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	CD40	_	PROPN	_	Number=Sing	_	_	_	_
24	ligand	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	positive	_	ADJ	_	Degree=Pos	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	CD40L	_	NOUN	_	Number=Sing	_	_	_	_
29	+	_	SYM	_	_	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	which	_	PRON	_	PronType=Rel	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	HD	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	general	_	ADJ	_	Degree=Pos	_	_	_	_
42	population	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
45	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
46	to	_	PART	_	_	_	_	_	_
47	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	disease	_	NOUN	_	Number=Sing	_	_	_	_
50	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
51	through	_	ADP	_	_	_	_	_	_
52	CD40	_	PROPN	_	Number=Sing	_	_	_	_
53	/	_	PUNCT	_	_	_	_	_	_
54	CD40L	_	PROPN	_	Number=Sing	_	_	_	_
55	interactions	_	NOUN	_	Number=Plur	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Conversely	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	RS	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	virtually	_	ADV	_	_	_	_	_	_
7	all	_	DET	_	_	_	_	_	_
8	HIV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	HD	_	NOUN	_	Number=Sing	_	_	_	_
11	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	EBV	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	latent	_	ADJ	_	Number=Sing	_	_	_	_
17	membrane	_	NOUN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	being	_	AUX	_	VerbForm=Ger	_	_	_	_
27	functionally	_	ADV	_	_	_	_	_	_
28	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	CD40	_	PROPN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	may	_	AUX	_	VerbForm=Fin	_	_	_	_
33	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	at	_	ADV	_	_	_	_	_	_
36	least	_	ADV	_	Degree=Sup	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	part	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	modulation	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	HIV	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	HD	_	NOUN	_	Number=Sing	_	_	_	_
48	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003202	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	subunit	_	NOUN	_	Number=Sing	_	_	_	_
8	p65	_	NUM	_	Number=Sing	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	sodium	_	NOUN	_	Number=Sing	_	_	_	_
21	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Lipopolysaccharide	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	one	_	NUM	_	NumType=Card	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	most	_	ADV	_	_	_	_	_	_
7	potent	_	ADJ	_	Degree=Pos	_	_	_	_
8	trigger	_	ADJ	_	Number=Sing	_	_	_	_
9	substances	_	NOUN	_	Number=Plur	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
14	causing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	secretion	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	mediators	_	NOUN	_	Number=Plur	_	_	_	_
19	such	_	ADJ	_	Degree=Pos	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	tumor	_	NOUN	_	Number=Sing	_	_	_	_
22	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nature	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	regulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	still	_	ADV	_	_	_	_	_	_
16	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	;	_	PUNCT	_	_	_	_	_	_
11	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	p50	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	p65	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
20	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	play	_	VERB	_	VerbForm=Inf	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	important	_	ADJ	_	Degree=Pos	_	_	_	_
25	role	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	mediators	_	NOUN	_	Number=Plur	_	_	_	_
32	when	_	ADV	_	PronType=Int	_	_	_	_
33	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
34	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Nonsteroidal	_	ADJ	_	Degree=Pos	_	_	_	_
2	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	drugs	_	NOUN	_	Number=Plur	_	_	_	_
4	such	_	ADJ	_	Degree=Pos	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	salicylates	_	NOUN	_	Number=Plur	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
9	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	treat	_	VERB	_	VerbForm=Inf	_	_	_	_
12	symptoms	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	new	_	ADJ	_	Degree=Pos	_	_	_	_
19	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	drug	_	NOUN	_	Number=Sing	_	_	_	_
22	action	_	NOUN	_	Number=Sing	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	recently	_	ADV	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Salicylates	_	NOUN	_	Number=Plur	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
7	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	via	_	ADP	_	_	_	_	_	_
13	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	SCONJ	_	_	_	_	_	_
21	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	degradation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
30	"	_	PUNCT	_	_	_	_	_	_
31	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
32	kappa	_	VERB	_	Number=Sing	_	_	_	_
33	B	_	PROPN	_	Number=Sing	_	_	_	_
34	"	_	PUNCT	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	translocation	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappa	_	NOUN	_	Number=Sing	_	_	_	_
43	B	_	NOUN	_	Number=Sing	_	_	_	_
44	into	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
47	compartment	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	nature	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	subunit	_	NOUN	_	Number=Sing	_	_	_	_
8	involved	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
12	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
15	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	salicylates	_	NOUN	_	Number=Plur	_	_	_	_
8	affect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	amount	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	active	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	PROPN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	Porphyromonas	_	PROPN	_	Number=Sing	_	_	_	_
32	gingivalis	_	PROPN	_	Degree=Pos	_	_	_	_
33	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	human	_	ADJ	_	Degree=Pos	_	_	_	_
37	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
40	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	High	_	ADJ	_	Degree=Pos	_	_	_	_
2	doses	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	sodium	_	NOUN	_	Number=Sing	_	_	_	_
5	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
6	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	p65	_	NUM	_	Number=Sing	_	_	_	_
12	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
13	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	suppression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	total	_	ADJ	_	Degree=Pos	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	p50	_	NOUN	_	Number=Sing	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	tissue	_	NOUN	_	Number=Sing	_	_	_	_
28	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
29	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	no	_	DET	_	_	_	_	_	_
31	effects	_	NOUN	_	Number=Plur	_	_	_	_
32	on	_	ADP	_	_	_	_	_	_
33	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappa	_	NOUN	_	Number=Sing	_	_	_	_
39	B	_	NOUN	_	Number=Sing	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	p65	_	NOUN	_	Number=Sing	_	_	_	_
7	subunit	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	salicylate	_	ADJ	_	Degree=Pos	_	_	_	_
6	treatment	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	highlight	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	control	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	mediators	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003205	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	ICSAT	_	PROPN	_	Number=Sing	_	_	_	_
2	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	cause	_	VERB	_	VerbForm=Inf	_	_	_	_
8	adult	_	NOUN	_	Number=Sing	_	_	_	_
9	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
10	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
13	myeloma	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	ICSAT	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
4	Consensus	_	NOUN	_	Number=Sing	_	_	_	_
5	Sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	Activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	member	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	interferon	_	NOUN	_	Number=Sing	_	_	_	_
22	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	IRF	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	family	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factors	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	originally	_	ADV	_	_	_	_	_	_
33	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	through	_	ADP	_	_	_	_	_	_
35	Southwestern	_	ADJ	_	Degree=Pos	_	_	_	_
36	screening	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	ATL	_	PROPN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	Adult	_	PROPN	_	Number=Sing	_	_	_	_
42	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
43	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	16T	_	NUM	_	NumType=Card	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	library	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	created	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
8	mice	_	NOUN	_	Number=Plur	_	_	_	_
9	overexpressing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	ICSAT	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	spontaneous	_	ADJ	_	Degree=Pos	_	_	_	_
3	tumorigenesis	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	Concanavalin	_	PROPN	_	Number=Sing	_	_	_	_
14	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	significantly	_	ADV	_	_	_	_	_	_
18	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
21	mice	_	NOUN	_	Number=Plur	_	_	_	_
22	overexpressing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	ICSAT	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	ICSAT	_	PROPN	_	Number=Sing	_	_	_	_
2	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	insufficient	_	ADJ	_	Degree=Pos	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	leukemogenesis	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	ATL	_	NOUN	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
14	myeloma	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	MM	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	however	_	ADV	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	may	_	AUX	_	VerbForm=Fin	_	_	_	_
23	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
24	T	_	DET	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
29	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
30	may	_	AUX	_	VerbForm=Fin	_	_	_	_
31	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	leukemogenesis	_	NOUN	_	Number=Sing	_	_	_	_
34	via	_	SCONJ	_	_	_	_	_	_
35	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	production	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1999	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003208	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	DNA	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	steroid	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	VERB	_	Number=Sing	_	_	_	_
6	domains	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	CLL	_	NOUN	_	Number=Sing	_	_	_	_
20	patients	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	aim	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	whether	_	SCONJ	_	_	_	_	_	_
10	mutations	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	could	_	AUX	_	VerbForm=Fin	_	_	_	_
16	account	_	VERB	_	VerbForm=Inf	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	unresponsiveness	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	patients	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
25	lymphatic	_	ADJ	_	Degree=Pos	_	_	_	_
26	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	CLL	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	combination	_	VERB	_	VerbForm=Inf	_	_	_	_
32	chemotherapy	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	tested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	immunocytochemically	_	ADV	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	assays	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	mutation	_	NOUN	_	Number=Sing	_	_	_	_
16	screening	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	denaturing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	gradient	_	ADJ	_	Number=Sing	_	_	_	_
20	gel	_	NOUN	_	Number=Sing	_	_	_	_
21	electrophoresis	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	receptor	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	concentration	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	as	_	SCONJ	_	_	_	_	_	_
6	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	staining	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	steroid	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	test	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	varied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	considerably	_	ADV	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	no	_	DET	_	_	_	_	_	_
19	clear	_	ADJ	_	Degree=Pos	_	_	_	_
20	correlation	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	highly	_	ADV	_	_	_	_	_	_
4	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
5	mutation	_	NOUN	_	Number=Sing	_	_	_	_
6	screening	_	NOUN	_	Number=Sing	_	_	_	_
7	assay	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	DNA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	steroid	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	region	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	none	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	treated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
23	patients	_	NOUN	_	Number=Plur	_	_	_	_
24	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	any	_	DET	_	_	_	_	_	_
26	mutation	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
32	receptor	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	CLL	_	NOUN	_	Number=Sing	_	_	_	_
36	patients	_	NOUN	_	Number=Plur	_	_	_	_
37	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	not	_	PART	_	_	_	_	_	_
40	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
43	domains	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	one	_	NUM	_	NumType=Card	_	_	_	_
3	individual	_	NOUN	_	Degree=Pos	_	_	_	_
4	who	_	PRON	_	PronType=Rel	_	_	_	_
5	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	before	_	ADP	_	_	_	_	_	_
10	analysis	_	NOUN	_	Number=Sing	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	silent	_	ADJ	_	Degree=Pos	_	_	_	_
13	mutation	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	one	_	NUM	_	NumType=Card	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	allele	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	than	_	ADP	_	_	_	_	_	_
8	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	ligand	_	NOUN	_	Number=Sing	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	lack	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	chemotherapy	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	relation	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	corticoid	_	ADJ	_	Degree=Pos	_	_	_	_
12	resistance	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	mouse	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	culture	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003211	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Block	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
4	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	32Dcl3	_	NUM	_	NumType=Card	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	AML1	_	PROPN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	ETO	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	MTG8	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	highly	_	ADV	_	_	_	_	_	_
19	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	chimeric	_	ADJ	_	Degree=Pos	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	AML1	_	PROPN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	ETO	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	MTG8	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	t	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	8	_	NUM	_	NumType=Card	_	_	_	_
17	;	_	PUNCT	_	_	_	_	_	_
18	21	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	acute	_	ADJ	_	Degree=Pos	_	_	_	_
21	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
22	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
23	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	evaluate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	primary	_	ADJ	_	Degree=Pos	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	AML1	_	PROPN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	ETO	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	leukemogenesis	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	effects	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	over	_	ADP	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	murine	_	NOUN	_	Number=Sing	_	_	_	_
29	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
30	precursor	_	NOUN	_	Number=Sing	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	line	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	32	_	NUM	_	NumType=Card	_	_	_	_
35	Dcl3	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	32Dcl3	_	NUM	_	NumType=Card	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
6	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	onset	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	morphological	_	ADJ	_	Degree=Pos	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	delayed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	even	_	ADV	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	very	_	ADV	_	_	_	_	_	_
8	high	_	ADJ	_	Degree=Pos	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
12	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	eventually	_	ADV	_	_	_	_	_	_
16	underwent	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	without	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	significant	_	ADJ	_	Degree=Pos	_	_	_	_
21	decrease	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	contrary	_	ADJ	_	Degree=Pos	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	32	_	NUM	_	NumType=Card	_	_	_	_
6	Dcl3	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	stably	_	ADV	_	_	_	_	_	_
9	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	AML1	_	PROPN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	ETO	_	PROPN	_	Number=Sing	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	completely	_	ADV	_	_	_	_	_	_
15	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	continued	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	grow	_	VERB	_	VerbForm=Inf	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	presence	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	G	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	CSF	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	interpretation	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	primary	_	ADJ	_	Degree=Pos	_	_	_	_
19	target	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	AML1	_	PROPN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	ETO	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003214	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cloning	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	murine	_	NOUN	_	Number=Sing	_	_	_	_
4	TCF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	T	_	NUM	_	NumType=Card	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	functional	_	ADJ	_	Degree=Pos	_	_	_	_
18	motifs	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	CD3	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	CD3	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	epsilon	_	NOUN	_	Degree=Pos	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	confined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	lineage	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	recently	_	ADV	_	_	_	_	_	_
4	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	TCF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	functional	_	ADJ	_	Degree=Pos	_	_	_	_
21	element	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	T	_	PROPN	_	Number=Sing	_	_	_	_
25	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	CD3	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	panel	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	lines	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	TCF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	T	_	ADJ	_	Number=Sing	_	_	_	_
17	lineage	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	TCF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	belonged	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	novel	_	NOUN	_	Number=Sing	_	_	_	_
8	family	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	so	_	ADV	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	high	_	ADJ	_	Degree=Pos	_	_	_	_
18	mobility	_	NOUN	_	Number=Sing	_	_	_	_
19	group	_	NOUN	_	Number=Sing	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	HMG	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	box	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cloning	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	murine	_	NOUN	_	Number=Sing	_	_	_	_
8	TCF	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	splice	_	NOUN	_	Number=Sing	_	_	_	_
3	alternatives	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	that	_	PRON	_	_	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	previously	_	ADV	_	_	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	TCF	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Murine	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	TCF	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	displayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	95.5	_	NUM	_	NumType=Card	_	_	_	_
10	%	_	SYM	_	Number=Sing	_	_	_	_
11	overall	_	ADJ	_	Degree=Pos	_	_	_	_
12	amino	_	NOUN	_	Number=Sing	_	_	_	_
13	acid	_	NOUN	_	Number=Sing	_	_	_	_
14	homology	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
2	murine	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	TCF	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	recognized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	same	_	ADJ	_	Degree=Pos	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	motif	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	CD3	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
18	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
19	as	_	SCONJ	_	_	_	_	_	_
20	judged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	gel	_	NOUN	_	Number=Sing	_	_	_	_
23	retardation	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	methylation	_	NOUN	_	Number=Sing	_	_	_	_
26	interference	_	NOUN	_	Number=Sing	_	_	_	_
27	assays	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	With	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	murine	_	NOUN	_	Number=Sing	_	_	_	_
4	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
5	clones	_	VERB	_	Number=Plur	_	_	_	_
6	several	_	ADJ	_	Degree=Pos	_	_	_	_
7	aspects	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	TCF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	First	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	deletion	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	region	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	TCF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	HMG	_	PROPN	_	Number=Sing	_	_	_	_
16	box	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	sequence	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Second	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	high	_	ADJ	_	Degree=Pos	_	_	_	_
5	stringency	_	NOUN	_	Number=Sing	_	_	_	_
6	Northern	_	ADJ	_	Number=Sing	_	_	_	_
7	blotting	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	situ	_	NOUN	_	Number=Sing	_	_	_	_
11	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	TCF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	confined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	thymus	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	areas	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	spleen	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Third	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	TCF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	bound	_	ADJ	_	Degree=Pos	_	_	_	_
7	specifically	_	ADV	_	_	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	functional	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	NumType=Card	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	element	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	TCR	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	lineage	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	affinity	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	functional	_	ADJ	_	Degree=Pos	_	_	_	_
12	motifs	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	TCR	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	CD3	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
22	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
23	imply	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	important	_	ADJ	_	Degree=Pos	_	_	_	_
26	role	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	TCF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	establishment	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	mature	_	ADJ	_	Degree=Pos	_	_	_	_
37	T	_	NOUN	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003216	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	tat	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	using	_	VERB	_	VerbForm=Ger	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	BK	_	PROPN	_	Number=Sing	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	vector	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	production	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	characterization	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	constitutively	_	ADV	_	_	_	_	_	_
11	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	functional	_	ADJ	_	Degree=Pos	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	immune	_	NOUN	_	Number=Sing	_	_	_	_
15	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	tat	_	NOUN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	using	_	VERB	_	VerbForm=Ger	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	BK	_	PROPN	_	Number=Sing	_	_	_	_
30	virus	_	NOUN	_	Number=Sing	_	_	_	_
31	plasmid	_	NOUN	_	Degree=Pos	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	vector	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	HIV	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	tat	_	NOUN	_	Number=Sing	_	_	_	_
39	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	growth	_	NOUN	_	Number=Sing	_	_	_	_
4	rate	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	tat	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	lines	_	NOUN	_	Number=Plur	_	_	_	_
12	as	_	SCONJ	_	_	_	_	_	_
13	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	control	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	lines	_	NOUN	_	Number=Plur	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003220	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	RB	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	E2F	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	MHC	_	PROPN	_	Number=Sing	_	_	_	_
12	class	_	NOUN	_	Number=Sing	_	_	_	_
13	II	_	NUM	_	NumType=Card	_	_	_	_
14	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
15	B-	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	lines	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	normal	_	ADJ	_	Degree=Pos	_	_	_	_
20	IFN	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	gamma	_	NOUN	_	Number=Sing	_	_	_	_
23	induction	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	class	_	NOUN	_	Number=Sing	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
29	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	class	_	NOUN	_	Number=Sing	_	_	_	_
32	II	_	NUM	_	NumType=Card	_	_	_	_
33	non-inducible	_	ADJ	_	Degree=Pos	_	_	_	_
34	RB	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	defective	_	ADJ	_	Degree=Pos	_	_	_	_
37	tumor	_	NOUN	_	Number=Sing	_	_	_	_
38	lines	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	major	_	ADJ	_	Degree=Pos	_	_	_	_
3	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	MHC	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	class	_	NOUN	_	Number=Sing	_	_	_	_
8	II	_	NUM	_	Number=Sing	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	encode	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	surface	_	NOUN	_	Number=Sing	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	antigenic	_	ADJ	_	Degree=Pos	_	_	_	_
17	peptide	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	presentation	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	class	_	NOUN	_	Number=Sing	_	_	_	_
3	II	_	NUM	_	Number=Sing	_	_	_	_
4	proteins	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	constitutively	_	ADV	_	_	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	EBV	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	IFN	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	gamma	_	NOUN	_	Number=Sing	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	wide	_	ADJ	_	Degree=Pos	_	_	_	_
30	variety	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	types	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Retinoblastoma	_	PROPN	_	Number=Sing	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	RB	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	tumor	_	NOUN	_	Number=Sing	_	_	_	_
9	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	functions	_	NOUN	_	Number=Plur	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	repressor	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	SCONJ	_	_	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	inactivating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
22	E2F	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	I	_	NUM	_	NumType=Card	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	RB	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	defective	_	ADJ	_	Degree=Pos	_	_	_	_
4	tumor	_	NOUN	_	Number=Sing	_	_	_	_
5	lines	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	non-inducible	_	ADJ	_	Degree=Pos	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	MHC	_	PROPN	_	Number=Sing	_	_	_	_
10	class	_	NOUN	_	Number=Sing	_	_	_	_
11	II	_	NUM	_	NumType=Card	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	IFN	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	gamma	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	very	_	ADV	_	_	_	_	_	_
19	weakly	_	ADV	_	Degree=Pos	_	_	_	_
20	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	transfection	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	different	_	ADJ	_	Degree=Pos	_	_	_	_
27	lines	_	NOUN	_	Number=Plur	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	RB	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	vectors	_	NOUN	_	Number=Plur	_	_	_	_
32	re	_	ADP	_	_	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	establishes	_	NOUN	_	Number=Plur	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	substantially	_	ADV	_	_	_	_	_	_
37	enhances	_	NOUN	_	Number=Plur	_	_	_	_
38	class	_	NOUN	_	Number=Sing	_	_	_	_
39	II	_	NUM	_	NumType=Card	_	_	_	_
40	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	RB	_	NOUN	_	Number=Sing	_	_	_	_
7	status	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	series	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	mutants	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	defective	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	class	_	NOUN	_	Number=Sing	_	_	_	_
21	II	_	NUM	_	NumType=Card	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	either	_	CCONJ	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	vitro	_	NOUN	_	Number=Sing	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	Bare	_	PROPN	_	Number=Sing	_	_	_	_
32	Lymphocyte	_	PROPN	_	Number=Sing	_	_	_	_
33	Syndrome	_	PROPN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	BLS	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	patients	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	matrix	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	bound	_	ADJ	_	Degree=Pos	_	_	_	_
5	RB	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	all	_	DET	_	_	_	_	_	_
10	cases	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	loss	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	RB	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	class	_	NOUN	_	Number=Sing	_	_	_	_
23	II	_	NUM	_	NumType=Card	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
27	lines	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	E2F	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	binding	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	most	_	ADV	_	_	_	_	_	_
10	likely	_	ADJ	_	Degree=Pos	_	_	_	_
11	DP	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	also	_	ADV	_	_	_	_	_	_
17	apparently	_	ADV	_	_	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	both	_	DET	_	_	_	_	_	_
21	class	_	NOUN	_	Number=Sing	_	_	_	_
22	II	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	positive	_	ADJ	_	Degree=Pos	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	negative	_	ADJ	_	Degree=Pos	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	lines	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	induction	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	RB	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	defective	_	ADJ	_	Degree=Pos	_	_	_	_
15	lines	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	class	_	NOUN	_	Number=Sing	_	_	_	_
5	II	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
8	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	defective	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	one	_	NUM	_	NumType=Card	_	_	_	_
14	form	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	BLS	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	induction	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	MHC	_	PROPN	_	Number=Sing	_	_	_	_
26	class	_	NOUN	_	Number=Sing	_	_	_	_
27	II	_	NUM	_	Number=Sing	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	IFN	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	gamma	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
2	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	normally	_	ADV	_	_	_	_	_	_
5	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	gamma	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	class	_	NOUN	_	Number=Sing	_	_	_	_
12	II	_	NUM	_	Number=Sing	_	_	_	_
13	non-inducible	_	ADJ	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	RB	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	defective	_	ADJ	_	Degree=Pos	_	_	_	_
18	lines	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	one	_	NUM	_	NumType=Card	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	re-expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	RB	_	PROPN	_	Number=Sing	_	_	_	_
28	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	no	_	DET	_	_	_	_	_	_
30	effect	_	NOUN	_	Number=Sing	_	_	_	_
31	on	_	ADP	_	_	_	_	_	_
32	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
33	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
34	induction	_	NOUN	_	Number=Sing	_	_	_	_
35	levels	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	block	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	MHC	_	PROPN	_	Number=Sing	_	_	_	_
7	class	_	NOUN	_	Number=Sing	_	_	_	_
8	II	_	NUM	_	NumType=Card	_	_	_	_
9	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	RB	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	defective	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	due	_	ADP	_	_	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	block	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
23	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003224	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	rhombotin	_	NOUN	_	Number=Sing	_	_	_	_
3	family	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	rich	_	ADJ	_	Degree=Pos	_	_	_	_
8	LIM	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	domain	_	NOUN	_	Number=Sing	_	_	_	_
11	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
12	:	_	PUNCT	_	_	_	_	_	_
13	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
14	members	_	NOUN	_	Number=Plur	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	involved	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
19	translocations	_	NOUN	_	Number=Plur	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	chromosomes	_	NOUN	_	Number=Plur	_	_	_	_
23	11p15	_	NUM	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	11p13	_	NUM	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
3	translocation	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
7	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
8	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	short	_	ADJ	_	Degree=Pos	_	_	_	_
11	arm	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
15	11	_	NUM	_	NumType=Card	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	band	_	NOUN	_	Number=Sing	_	_	_	_
18	11p15	_	NUM	_	Number=Sing	_	_	_	_
19	disrupts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	rhombotin	_	NOUN	_	Degree=Pos	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	duplicated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	rich	_	ADJ	_	Degree=Pos	_	_	_	_
11	regions	_	NOUN	_	Number=Plur	_	_	_	_
12	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	LIM	_	PROPN	_	Number=Sing	_	_	_	_
14	domains	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	homology	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	zinc	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	binding	_	VERB	_	Number=Sing	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	iron	_	VERB	_	VerbForm=Inf	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	sulfur	_	NOUN	_	Number=Sing	_	_	_	_
29	centers	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	ferredoxins	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	homologues	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	rhombotin	_	NOUN	_	Degree=Pos	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	now	_	ADV	_	_	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	Rhom	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
15	11	_	NUM	_	NumType=Card	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	band	_	NOUN	_	Number=Sing	_	_	_	_
18	11p13	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	where	_	ADV	_	PronType=Rel	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	cluster	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
25	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	translocations	_	NOUN	_	Number=Plur	_	_	_	_
29	occur	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	;	_	PUNCT	_	_	_	_	_	_
31	all	_	DET	_	_	_	_	_	_
32	translocation	_	NOUN	_	Number=Sing	_	_	_	_
33	breakpoints	_	NOUN	_	Number=Plur	_	_	_	_
34	at	_	ADP	_	_	_	_	_	_
35	11p13	_	NUM	_	NumType=Card	_	_	_	_
36	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
37	upstream	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	Rhom	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	2	_	NUM	_	NumType=Card	_	_	_	_
43	gene	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	mouse	_	NOUN	_	Number=Sing	_	_	_	_
4	Rhom	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	highly	_	ADV	_	_	_	_	_	_
9	conserved	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	like	_	ADP	_	_	_	_	_	_
13	rhombotin	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	encode	_	VERB	_	Number=Sing	_	_	_	_
16	two	_	NUM	_	NumType=Card	_	_	_	_
17	tandem	_	NOUN	_	Number=Sing	_	_	_	_
18	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	rich	_	ADJ	_	Degree=Pos	_	_	_	_
21	LIM	_	NOUN	_	Number=Sing	_	_	_	_
22	domains	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Rhom	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	early	_	ADJ	_	Degree=Pos	_	_	_	_
9	mouse	_	NOUN	_	Number=Sing	_	_	_	_
10	development	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	central	_	ADJ	_	Degree=Pos	_	_	_	_
13	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
14	system	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	lung	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	kidney	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	liver	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	spleen	_	NOUN	_	Number=Sing	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	only	_	ADV	_	_	_	_	_	_
26	very	_	ADV	_	_	_	_	_	_
27	low	_	ADJ	_	Degree=Pos	_	_	_	_
28	levels	_	NOUN	_	Number=Plur	_	_	_	_
29	occur	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	thymus	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	Rhom	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
14	11	_	NUM	_	NumType=Card	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	also	_	ADV	_	_	_	_	_	_
17	retains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	homology	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	LIM	_	PROPN	_	Number=Sing	_	_	_	_
22	domain	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	rhombotin	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	Rhom	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	such	_	DET	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	common	_	ADJ	_	Degree=Pos	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
14	damage	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
17	tumors	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	consistency	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	translocations	_	NOUN	_	Number=Plur	_	_	_	_
23	near	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	rhombotin	_	NOUN	_	Degree=Pos	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	further	_	ADV	_	_	_	_	_	_
29	examined	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	translocation	_	NOUN	_	Number=Sing	_	_	_	_
4	adjacent	_	ADJ	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	rhombotin	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	same	_	ADJ	_	Degree=Pos	_	_	_	_
13	position	_	NOUN	_	Number=Sing	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	previous	_	ADJ	_	Degree=Pos	_	_	_	_
18	example	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	chromosome	_	NOUN	_	Degree=Pos	_	_	_	_
4	bands	_	NOUN	_	Number=Plur	_	_	_	_
5	11p15	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	rhombotin	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	11p13	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	Rhom	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	chromosome	_	NOUN	_	Degree=Pos	_	_	_	_
21	translocation	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
24	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	11p15	_	NUM	_	NumType=Card	_	_	_	_
29	target	_	NOUN	_	Number=Sing	_	_	_	_
30	more	_	ADV	_	_	_	_	_	_
31	rarely	_	ADV	_	_	_	_	_	_
32	involved	_	ADJ	_	Degree=Pos	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	define	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	rhombotin	_	NOUN	_	Degree=Pos	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	family	_	NOUN	_	Number=Sing	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	class	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
13	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	duplicated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
16	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	rich	_	ADJ	_	Degree=Pos	_	_	_	_
19	LIM	_	NOUN	_	Number=Sing	_	_	_	_
20	domains	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003225	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Aiolos	_	PROPN	_	Number=Sing	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	controls	_	NOUN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	death	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	by	_	SCONJ	_	_	_	_	_	_
11	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
19	localization	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	searched	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	proteins	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	Ras	_	PROPN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	-2	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	deprived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	Aiolos	_	PROPN	_	Number=Sing	_	_	_	_
32	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	Ras	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Ras	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Aiolos	_	PROPN	_	Number=Sing	_	_	_	_
5	interaction	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	vitro	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	vivo	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	co-immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Indirect	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
3	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	controls	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	distribution	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Aiolos	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
18	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	Ras	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	functional	_	ADJ	_	Degree=Pos	_	_	_	_
5	Aiolos	_	NOUN	_	Number=Plur	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	sites	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	able	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
23	reporter	_	NOUN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Aiolos	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	binding	_	VERB	_	Number=Sing	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	within	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
14	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	reporter	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	direct	_	ADJ	_	Degree=Pos	_	_	_	_
23	control	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	Aiolos	_	PROPN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Co	_	X	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	transfection	_	NOUN	_	Number=Sing	_	_	_	_
4	experiments	_	NOUN	_	Number=Plur	_	_	_	_
5	confirm	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	Aiolos	_	PROPN	_	Number=Sing	_	_	_	_
8	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	deprived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	model	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	via	_	ADP	_	_	_	_	_	_
14	Aiolos	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003226	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
2	promote	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	nonphlogistic	_	ADJ	_	Degree=Pos	_	_	_	_
4	phagocytosis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
7	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Phagocyte	_	NOUN	_	Number=Sing	_	_	_	_
2	recognition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	uptake	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	nonphlogistic	_	ADJ	_	Degree=Pos	_	_	_	_
8	degradation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	other	_	ADJ	_	Degree=Pos	_	_	_	_
13	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	undergoing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
16	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	resolution	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	assessed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	leukocyte	_	ADJ	_	Number=Sing	_	_	_	_
12	clearance	_	NOUN	_	Number=Sing	_	_	_	_
13	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	"	_	PUNCT	_	_	_	_	_	_
4	semimature	_	NOUN	_	Number=Sing	_	_	_	_
5	"	_	PUNCT	_	_	_	_	_	_
6	5	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	day	_	NOUN	_	Number=Sing	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	M	_	NOUN	_	Number=Sing	_	_	_	_
16	phi	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	24	_	NUM	_	NumType=Card	_	_	_	_
20	h	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	methylprednisolone	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	hydrocortisone	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	not	_	ADV	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	nonglucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
33	steroids	_	NOUN	_	Number=Plur	_	_	_	_
34	aldosterone	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	estradiol	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	potentiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	phagocytosis	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
45	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	potentiated	_	VERB	_	Degree=Pos	_	_	_	_
9	phagocytosis	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
12	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	completely	_	ADV	_	_	_	_	_	_
15	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
21	RU38486	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
25	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
28	5	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	day	_	NOUN	_	Number=Sing	_	_	_	_
31	M	_	NOUN	_	Number=Sing	_	_	_	_
32	phi	_	NOUN	_	Number=Sing	_	_	_	_
33	ingestion	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	opsonized	_	VERB	_	Degree=Pos	_	_	_	_
36	erythrocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
5	potentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	5	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	day	_	NOUN	_	Number=Sing	_	_	_	_
12	M	_	NOUN	_	Number=Sing	_	_	_	_
13	phi	_	NOUN	_	Number=Sing	_	_	_	_
14	uptake	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
17	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
18	"	_	PUNCT	_	_	_	_	_	_
19	targets	_	NOUN	_	Number=Plur	_	_	_	_
20	"	_	PUNCT	_	_	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	Jurkat	_	ADJ	_	Number=Sing	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	uptake	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
33	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
36	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	human	_	ADJ	_	Degree=Pos	_	_	_	_
39	glomerular	_	ADJ	_	Degree=Pos	_	_	_	_
40	mesangial	_	ADJ	_	Degree=Pos	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	murine	_	NOUN	_	Number=Sing	_	_	_	_
44	M	_	PROPN	_	Number=Sing	_	_	_	_
45	phi	_	NOUN	_	Number=Sing	_	_	_	_
46	elicited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	into	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	peritoneum	_	NOUN	_	Number=Sing	_	_	_	_
50	or	_	CCONJ	_	_	_	_	_	_
51	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
52	from	_	ADP	_	_	_	_	_	_
53	bone	_	NOUN	_	Number=Sing	_	_	_	_
54	marrow	_	NOUN	_	Number=Sing	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Importantly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	methylprednisolone	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
6	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	uptake	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
12	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
13	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	trigger	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	release	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	chemokines	_	NOUN	_	Number=Plur	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	8	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	monocyte	_	VERB	_	Number=Sing	_	_	_	_
26	chemoattractant	_	NOUN	_	Number=Sing	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	longer	_	ADJ	_	Degree=Cmp	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	term	_	NOUN	_	Number=Sing	_	_	_	_
6	potentiation	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	methylprednisolone	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	SCONJ	_	_	_	_	_	_
12	maturing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	M	_	NOUN	_	Number=Sing	_	_	_	_
18	phi	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
22	increases	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	5	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	day	_	NOUN	_	Number=Sing	_	_	_	_
27	M	_	NOUN	_	Number=Sing	_	_	_	_
28	phi	_	NOUN	_	Number=Sing	_	_	_	_
29	uptake	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	being	_	AUX	_	VerbForm=Ger	_	_	_	_
34	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	earlier	_	ADJ	_	Degree=Cmp	_	_	_	_
37	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
38	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
39	added	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	during	_	ADP	_	_	_	_	_	_
41	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
42	maturation	_	NOUN	_	Number=Sing	_	_	_	_
43	into	_	ADP	_	_	_	_	_	_
44	M	_	PROPN	_	Number=Sing	_	_	_	_
45	phi	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	potentiation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	nonphlogistic	_	ADJ	_	Degree=Pos	_	_	_	_
7	clearance	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
10	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	hitherto	_	NOUN	_	_	_	_	_	_
16	unrecognized	_	ADJ	_	Degree=Pos	_	_	_	_
17	property	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	potential	_	ADJ	_	Degree=Pos	_	_	_	_
23	implications	_	NOUN	_	Number=Plur	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	therapies	_	NOUN	_	Number=Plur	_	_	_	_
26	aimed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	at	_	SCONJ	_	_	_	_	_	_
28	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	resolution	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
33	diseases	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003229	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	signal	_	NOUN	_	Number=Sing	_	_	_	_
8	transduction	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	OBJECTIVE	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	inter	_	NOUN	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	relationship	_	NOUN	_	Number=Sing	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	infection	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	surface	_	NOUN	_	Number=Sing	_	_	_	_
16	receptors	_	NOUN	_	Number=Plur	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	tumor	_	NOUN	_	Number=Sing	_	_	_	_
19	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	TNF	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	immunoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
29	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
30	that	_	PRON	_	PronType=Rel	_	_	_	_
31	can	_	AUX	_	VerbForm=Fin	_	_	_	_
32	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
33	HIV	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	replication	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	DESIGN	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	because	_	SCONJ	_	_	_	_	_	_
11	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
12	normally	_	ADV	_	_	_	_	_	_
13	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	both	_	DET	_	_	_	_	_	_
15	types	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	TNF	_	NOUN	_	Number=Sing	_	_	_	_
18	receptors	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	TNF	_	PROPN	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	surface	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
12	antibody	_	NOUN	_	Number=Sing	_	_	_	_
13	recognition	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	flow	_	VERB	_	VerbForm=Inf	_	_	_	_
16	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	signal	_	NOUN	_	Number=Sing	_	_	_	_
20	transduction	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	gel	_	NOUN	_	Number=Sing	_	_	_	_
25	shift	_	NOUN	_	Number=Sing	_	_	_	_
26	analysis	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	quantitated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	reverse	_	NOUN	_	Number=Sing	_	_	_	_
11	transcriptase	_	NOUN	_	Number=Sing	_	_	_	_
12	assay	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	OM	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	10.1	_	NUM	_	NumType=Card	_	_	_	_
6	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
7	model	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
10	infection	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	HIV	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	also	_	ADV	_	_	_	_	_	_
22	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
26	increase	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	75	_	NUM	_	NumType=Card	_	_	_	_
29	kd	_	NOUN	_	Number=Sing	_	_	_	_
30	TNF	_	PROPN	_	Number=Sing	_	_	_	_
31	receptor	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	TR75	_	NUM	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	although	_	SCONJ	_	_	_	_	_	_
37	55	_	NUM	_	NumType=Card	_	_	_	_
38	kD	_	NOUN	_	Number=Sing	_	_	_	_
39	TNF	_	PROPN	_	Number=Sing	_	_	_	_
40	receptor	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	TR55	_	NUM	_	NumType=Card	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	levels	_	NOUN	_	Number=Plur	_	_	_	_
45	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
46	not	_	PART	_	_	_	_	_	_
47	dramatically	_	ADV	_	_	_	_	_	_
48	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	series	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	uninfected	_	ADJ	_	Degree=Pos	_	_	_	_
5	parental	_	ADJ	_	Number=Sing	_	_	_	_
6	HL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	60	_	NUM	_	NumType=Card	_	_	_	_
9	subclones	_	NOUN	_	Number=Plur	_	_	_	_
10	all	_	ADV	_	_	_	_	_	_
11	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	TR75	_	NUM	_	NumType=Card	_	_	_	_
13	surface	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	response	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	TNF	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	treatment	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Enhanced	_	PROPN	_	Tense=Past|VerbForm=Part	_	_	_	_

1	TR75	_	NUM	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	OM	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	10.1	_	NUM	_	NumType=Card	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	followed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	same	_	ADJ	_	Degree=Pos	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dose	_	NOUN	_	Number=Sing	_	_	_	_
16	dependency	_	NOUN	_	Number=Sing	_	_	_	_
17	as	_	SCONJ	_	_	_	_	_	_
18	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
19	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	HIV	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	production	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	increase	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	TR75	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	evident	_	ADJ	_	Degree=Pos	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	peak	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	acute	_	ADJ	_	Degree=Pos	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	infection	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	HL	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	60	_	NUM	_	NumType=Card	_	_	_	_
23	promyelocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	TR55	_	NUM	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	unaltered	_	ADJ	_	Degree=Pos	_	_	_	_
6	during	_	ADP	_	_	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	still	_	ADV	_	_	_	_	_	_
19	involved	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	viral	_	ADJ	_	Degree=Pos	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	process	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Antibody	_	PROPN	_	Number=Sing	_	_	_	_
2	cross	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	linking	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	TR55	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	absence	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
13	TNF	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	up	_	ADJ	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	modulation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	surface	_	NOUN	_	Number=Sing	_	_	_	_
30	TR75	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
34	NF	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappa	_	NOUN	_	Number=Sing	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	activity	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	OM	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	10.1	_	NUM	_	NumType=Card	_	_	_	_
43	cultures	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Surprisingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	case	_	NOUN	_	Number=Sing	_	_	_	_
7	even	_	ADV	_	_	_	_	_	_
8	when	_	ADV	_	PronType=Int	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	antagonistic	_	ADJ	_	Degree=Pos	_	_	_	_
11	anti-TR55	_	NOUN	_	Degree=Pos	_	_	_	_
12	antibody	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Anti-TR55	_	NUM	_	_	_	_	_	_
2	antibody	_	NOUN	_	Number=Sing	_	_	_	_
3	cross	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	chronically	_	ADV	_	_	_	_	_	_
8	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	U1	_	PROPN	_	Number=Sing	_	_	_	_
10	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cultures	_	NOUN	_	Number=Plur	_	_	_	_
12	could	_	AUX	_	VerbForm=Fin	_	_	_	_
13	only	_	ADV	_	_	_	_	_	_
14	partially	_	ADV	_	_	_	_	_	_
15	substitute	_	VERB	_	VerbForm=Inf	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	TNF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	HIV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	infection	_	NOUN	_	Number=Sing	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	selectively	_	ADV	_	_	_	_	_	_
11	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	surface	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	receptors	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	potentially	_	ADV	_	_	_	_	_	_
20	influencing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	own	_	ADJ	_	Degree=Pos	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	altering	_	VERB	_	VerbForm=Ger	_	_	_	_
26	normal	_	ADJ	_	Degree=Pos	_	_	_	_
27	immunoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	signal	_	NOUN	_	Number=Sing	_	_	_	_
29	transduction	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003231	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	chimeric	_	ADJ	_	Degree=Pos	_	_	_	_
3	type	_	NOUN	_	Number=Sing	_	_	_	_
4	II	_	NUM	_	NumType=Card	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	interleukin	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	type	_	NOUN	_	Number=Sing	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	interleukin	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1R	_	NUM	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	capable	_	ADJ	_	Degree=Pos	_	_	_	_
15	of	_	SCONJ	_	_	_	_	_	_
16	transducing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	signal	_	NOUN	_	Number=Sing	_	_	_	_
19	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	T	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	signal	_	NOUN	_	Number=Sing	_	_	_	_
3	transduction	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
9	domain	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	consists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	213	_	NUM	_	NumType=Card	_	_	_	_
15	amino	_	ADJ	_	Number=Sing	_	_	_	_
16	acids	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	receptor	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	II	_	NUM	_	NumType=Card	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1R	_	PROPN	_	Number=Sing	_	_	_	_
15	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	small	_	ADJ	_	Degree=Pos	_	_	_	_
18	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
19	tail	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	clear	_	ADJ	_	Degree=Pos	_	_	_	_
26	whether	_	SCONJ	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	receptor	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	signal	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	transducing	_	NOUN	_	Number=Sing	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
37	molecule	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	II	_	NUM	_	NumType=Card	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1R	_	NUM	_	Number=Sing	_	_	_	_
11	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	composed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	transmembrane	_	ADJ	_	Number=Sing	_	_	_	_
12	regions	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	type	_	NOUN	_	Number=Sing	_	_	_	_
17	II	_	NUM	_	NumType=Card	_	_	_	_
18	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	fused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
25	domain	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	type	_	NOUN	_	Number=Sing	_	_	_	_
30	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1R	_	PROPN	_	Number=Sing	_	_	_	_
34	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
35	capable	_	ADJ	_	Degree=Pos	_	_	_	_
36	of	_	SCONJ	_	_	_	_	_	_
37	transducing	_	VERB	_	VerbForm=Ger	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	signal	_	NOUN	_	Number=Sing	_	_	_	_
40	across	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	membrane	_	NOUN	_	Number=Sing	_	_	_	_
43	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
46	pattern	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	gene	_	NOUN	_	Number=Sing	_	_	_	_
49	activation	_	NOUN	_	Number=Sing	_	_	_	_
50	identical	_	ADJ	_	Degree=Pos	_	_	_	_
51	to	_	ADP	_	_	_	_	_	_
52	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
53	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
54	by	_	ADP	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	type	_	NOUN	_	Number=Sing	_	_	_	_
57	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
58	IL	_	PROPN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	1R	_	NUM	_	Number=Sing	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	domain	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	II	_	NUM	_	NumType=Card	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1R	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	capable	_	ADJ	_	Degree=Pos	_	_	_	_
17	of	_	SCONJ	_	_	_	_	_	_
18	functionally	_	ADV	_	_	_	_	_	_
19	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	transmitting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	signal	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
32	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
33	domain	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003234	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	normal	_	ADJ	_	Degree=Pos	_	_	_	_
4	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
5	D	_	NOUN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	messenger	_	NOUN	_	Number=Sing	_	_	_	_
8	ribonucleic	_	NOUN	_	Degree=Pos	_	_	_	_
9	acid	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	genotype	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	absorptive	_	ADJ	_	Degree=Pos	_	_	_	_
14	hypercalciuria	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Absorptive	_	ADJ	_	Degree=Pos	_	_	_	_
2	hypercalciuria	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	stone	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
8	condition	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	gut	_	NOUN	_	Degree=Pos	_	_	_	_
14	hyperabsorption	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	calcium	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	hypercalciuria	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	bone	_	NOUN	_	Number=Sing	_	_	_	_
23	density	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Inasmuch	_	ADJ	_	Degree=Pos	_	_	_	_
2	as	_	SCONJ	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	features	_	NOUN	_	Number=Plur	_	_	_	_
5	implicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	calcitriol	_	NOUN	_	Number=Sing	_	_	_	_
8	action	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	gut	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	bone	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
18	D	_	PROPN	_	Number=Sing	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	VDR	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	ascertain	_	VERB	_	VerbForm=Inf	_	_	_	_
26	whether	_	SCONJ	_	_	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	abnormality	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	marks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	patients	_	NOUN	_	Number=Plur	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	intestinal	_	ADJ	_	Degree=Pos	_	_	_	_
36	hyperabsorption	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	calcium	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	frequency	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	restriction	_	NOUN	_	Number=Sing	_	_	_	_
9	fragment	_	NOUN	_	Number=Sing	_	_	_	_
10	length	_	NOUN	_	Number=Sing	_	_	_	_
11	polymorphism	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	Bsm	_	PROPN	_	Number=Sing	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	associated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	different	_	ADJ	_	Degree=Pos	_	_	_	_
19	alleles	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	VDR	_	PROPN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	group	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	33	_	NUM	_	NumType=Card	_	_	_	_
29	well	_	ADV	_	Degree=Pos	_	_	_	_
30	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	absorptive	_	ADJ	_	Degree=Pos	_	_	_	_
32	hypercalciuric	_	ADJ	_	Degree=Pos	_	_	_	_
33	patients	_	NOUN	_	Number=Plur	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	group	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	36	_	NUM	_	NumType=Card	_	_	_	_
39	normal	_	ADJ	_	Degree=Pos	_	_	_	_
40	race	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	age	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	matched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	control	_	NOUN	_	Number=Sing	_	_	_	_
47	subjects	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	difference	_	NOUN	_	Number=Sing	_	_	_	_
5	between	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	distribution	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	VDR	_	NOUN	_	Number=Sing	_	_	_	_
11	alleles	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	patient	_	ADJ	_	Number=Sing	_	_	_	_
15	population	_	NOUN	_	Number=Sing	_	_	_	_
16	when	_	ADV	_	PronType=Int	_	_	_	_
17	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	normal	_	ADJ	_	Degree=Pos	_	_	_	_
21	population	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	coding	_	NOUN	_	Number=Sing	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	VDR	_	PROPN	_	Number=Sing	_	_	_	_
6	messenger	_	NOUN	_	Number=Sing	_	_	_	_
7	RNA	_	PROPN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	normal	_	ADJ	_	Degree=Pos	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	as	_	SCONJ	_	_	_	_	_	_
13	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	DNA	_	PROPN	_	Number=Sing	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	analysis	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	chemical	_	ADJ	_	Degree=Pos	_	_	_	_
21	mismatch	_	NOUN	_	Number=Sing	_	_	_	_
22	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
23	analysis	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	copy	_	NOUN	_	Number=Sing	_	_	_	_
26	DNA	_	PROPN	_	Number=Sing	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	11	_	NUM	_	NumType=Card	_	_	_	_
29	index	_	NOUN	_	Number=Sing	_	_	_	_
30	absorptive	_	ADJ	_	Degree=Pos	_	_	_	_
31	hypercalciuric	_	ADJ	_	Number=Sing	_	_	_	_
32	patients	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	basis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	results	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	intestinal	_	ADJ	_	Degree=Pos	_	_	_	_
14	calcium	_	NOUN	_	Number=Sing	_	_	_	_
15	absorption	_	NOUN	_	Number=Sing	_	_	_	_
16	invariably	_	ADV	_	_	_	_	_	_
17	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	absorptive	_	ADJ	_	Degree=Pos	_	_	_	_
20	hypercalciuria	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	attendant	_	NOUN	_	Number=Sing	_	_	_	_
23	symptoms	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	disorder	_	NOUN	_	Number=Sing	_	_	_	_
27	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	attributable	_	ADJ	_	Degree=Pos	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	mutations	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	VDR	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
37	not	_	PART	_	_	_	_	_	_
38	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	common	_	ADJ	_	Degree=Pos	_	_	_	_
42	VDR	_	NOUN	_	Number=Sing	_	_	_	_
43	genotype	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003239	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cyclic	_	ADJ	_	Number=Sing	_	_	_	_
4	adenosine	_	NOUN	_	Degree=Pos	_	_	_	_
5	monophosphate	_	NOUN	_	Number=Sing	_	_	_	_
6	signaling	_	VERB	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	platelets	_	NOUN	_	Number=Plur	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
11	patients	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	bipolar	_	ADJ	_	Degree=Pos	_	_	_	_
14	disorder	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	cyclic	_	ADJ	_	Number=Sing	_	_	_	_
7	adenosine	_	ADJ	_	Number=Sing	_	_	_	_
8	monophosphate	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
15	system	_	NOUN	_	Number=Sing	_	_	_	_
16	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
18	recently	_	ADV	_	_	_	_	_	_
19	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	patients	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	bipolar	_	ADJ	_	Degree=Pos	_	_	_	_
24	disorder	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	evaluated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	immunoreactivity	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	catalytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	subunits	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	kinase	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	kinase	_	NOUN	_	Number=Sing	_	_	_	_
20	A	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	substrates	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	Rap1	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	platelets	_	NOUN	_	Number=Plur	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
34	euthymic	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	manic	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	depressed	_	ADJ	_	Degree=Pos	_	_	_	_
40	patients	_	NOUN	_	Number=Plur	_	_	_	_
41	with	_	ADP	_	_	_	_	_	_
42	bipolar	_	ADJ	_	Degree=Pos	_	_	_	_
43	disorder	_	NOUN	_	Number=Sing	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
46	subjects	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Platelets	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	collected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	112	_	NUM	_	NumType=Card	_	_	_	_
8	drug	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	free	_	ADJ	_	Degree=Pos	_	_	_	_
11	patients	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	bipolar	_	ADJ	_	Degree=Pos	_	_	_	_
14	disorder	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	52	_	NUM	_	NumType=Card	_	_	_	_
17	euthymic	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	29	_	NUM	_	NumType=Card	_	_	_	_
20	depressed	_	ADJ	_	Degree=Pos	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	31	_	NUM	_	NumType=Card	_	_	_	_
24	manic	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	62	_	NUM	_	NumType=Card	_	_	_	_
28	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
29	subjects	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	Rap1	_	PROPN	_	Number=Sing	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	Western	_	ADJ	_	Degree=Pos	_	_	_	_
15	blot	_	NOUN	_	Number=Sing	_	_	_	_
16	analysis	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	immunostaining	_	ADJ	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	computer	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	assisted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	imaging	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	immunolabeling	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	catalytic	_	ADJ	_	Degree=Pos	_	_	_	_
6	subunit	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	significantly	_	ADV	_	_	_	_	_	_
15	different	_	ADJ	_	Degree=Pos	_	_	_	_
16	among	_	ADP	_	_	_	_	_	_
17	groups	_	NOUN	_	Number=Plur	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	P<.001	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
24	values	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
27	depressed	_	ADJ	_	Degree=Pos	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	manic	_	ADJ	_	Degree=Pos	_	_	_	_
30	patients	_	NOUN	_	Number=Plur	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	bipolar	_	ADJ	_	Degree=Pos	_	_	_	_
33	disorder	_	NOUN	_	Number=Sing	_	_	_	_
34	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
37	euthymic	_	ADJ	_	Degree=Pos	_	_	_	_
38	patients	_	NOUN	_	Number=Plur	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	bipolar	_	ADJ	_	Degree=Pos	_	_	_	_
41	disorder	_	NOUN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
44	subjects	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	significant	_	ADJ	_	Degree=Pos	_	_	_	_
3	differences	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	immunolabeling	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	subunits	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	type	_	NOUN	_	Number=Sing	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	II	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	kinase	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	immunolabeling	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Rap1	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	significantly	_	ADV	_	_	_	_	_	_
7	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	P<.001	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
13	euthymic	_	ADJ	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	depressed	_	ADJ	_	Degree=Pos	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	manic	_	ADJ	_	Degree=Pos	_	_	_	_
19	patients	_	NOUN	_	Number=Plur	_	_	_	_
20	than	_	ADP	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
23	persons	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Levels	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Rap1	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	catalytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	subunit	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	platelets	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	bipolar	_	ADJ	_	Degree=Pos	_	_	_	_
23	patients	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	may	_	AUX	_	VerbForm=Fin	_	_	_	_
4	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
5	clues	_	NOUN	_	Number=Plur	_	_	_	_
6	toward	_	SCONJ	_	_	_	_	_	_
7	understanding	_	VERB	_	VerbForm=Ger	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	involvement	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
12	signaling	_	VERB	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	bipolar	_	ADJ	_	Degree=Pos	_	_	_	_
18	disorder	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003242	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Phorbol	_	PROPN	_	Number=Sing	_	_	_	_
2	ester	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	mitogen	_	ADJ	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	kinase	_	NOUN	_	Number=Sing	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	MEK	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
22	PD98059	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	purpose	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	evaluate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	whether	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
20	pathway	_	NOUN	_	Number=Sing	_	_	_	_
21	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	13	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	acetate	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	TPA	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
34	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	human	_	ADJ	_	Degree=Pos	_	_	_	_
38	myeloblastic	_	ADJ	_	Number=Sing	_	_	_	_
39	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
40	ML	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	TPA	_	NOUN	_	Number=Sing	_	_	_	_
3	treatment	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	ERK1	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	ERK2	_	PROPN	_	Number=Sing	_	_	_	_
11	rapidly	_	ADV	_	_	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	between	_	ADP	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	h	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	while	_	SCONJ	_	_	_	_	_	_
24	ERK2	_	PROPN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	levels	_	NOUN	_	Number=Plur	_	_	_	_
27	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	constant	_	ADJ	_	Degree=Pos	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	JNK1	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	significantly	_	ADV	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	with	_	SCONJ	_	_	_	_	_	_
11	JNK1	_	PROPN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	levels	_	NOUN	_	Number=Plur	_	_	_	_
14	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	moderately	_	ADV	_	_	_	_	_	_
16	during	_	ADP	_	_	_	_	_	_
17	exposure	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	TPA	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	PD98059	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	mitogen	_	ADJ	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	kinase	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	MEK	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	TPA	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	ERK2	_	PROPN	_	Number=Sing	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	PD98059	_	NOUN	_	Number=Sing	_	_	_	_
4	completely	_	ADV	_	_	_	_	_	_
5	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	TPA	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	ML	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	as	_	SCONJ	_	_	_	_	_	_
18	assessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	number	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	features	_	NOUN	_	Number=Plur	_	_	_	_
24	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
28	including	_	VERB	_	VerbForm=Ger	_	_	_	_
29	changes	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	morphology	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	nonspecific	_	ADJ	_	Degree=Pos	_	_	_	_
34	esterase	_	NOUN	_	Number=Sing	_	_	_	_
35	activity	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	phagocytic	_	ADJ	_	Degree=Pos	_	_	_	_
38	ability	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	NADPH	_	NOUN	_	Number=Sing	_	_	_	_
41	oxidase	_	NOUN	_	Number=Sing	_	_	_	_
42	activity	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	mitochondrial	_	NOUN	_	Degree=Pos	_	_	_	_
45	respiration	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	c	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	jun	_	X	_	Number=Sing	_	_	_	_
51	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
52	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	MEK	_	PROPN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	ERK	_	PROPN	_	Number=Sing	_	_	_	_
10	signaling	_	NOUN	_	Number=Sing	_	_	_	_
11	pathway	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	TPA	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003247	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Estrogen	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	survival	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	monoblastoid	_	ADJ	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	undergoing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	mononucleated	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
10	process	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	SCONJ	_	_	_	_	_	_
12	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	intensity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	immune	_	ADJ	_	Degree=Pos	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	female	_	ADJ	_	Degree=Pos	_	_	_	_
3	steroid	_	NOUN	_	Number=Sing	_	_	_	_
4	hormones	_	NOUN	_	Number=Plur	_	_	_	_
5	estrogen	_	VERB	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	E2	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	Prog	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	reactivity	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	immune	_	NOUN	_	Number=Sing	_	_	_	_
23	system	_	NOUN	_	Number=Sing	_	_	_	_
24	;	_	PUNCT	_	_	_	_	_	_
25	recently	_	ADV	_	_	_	_	_	_
26	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
27	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
29	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	that	_	SCONJ	_	_	_	_	_	_
31	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
32	can	_	AUX	_	VerbForm=Fin	_	_	_	_
33	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
34	induction	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	osteoblasts	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
9	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	well	_	ADV	_	Degree=Pos	_	_	_	_
12	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	E2	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	Prog	_	PROPN	_	Number=Sing	_	_	_	_
7	could	_	AUX	_	VerbForm=Fin	_	_	_	_
8	interfere	_	VERB	_	VerbForm=Inf	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	TNF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	monoblastoid	_	ADJ	_	Number=Sing	_	_	_	_
19	U937	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	line	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	E2	_	NUM	_	Number=Sing	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	Prog	_	PROPN	_	Number=Sing	_	_	_	_
6	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	survival	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	prevented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	TNF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	undifferentiated	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	like	_	ADP	_	_	_	_	_	_
23	PMA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	differentiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	U937	_	NUM	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	as	_	SCONJ	_	_	_	_	_	_
30	assessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	trypan	_	NOUN	_	Number=Sing	_	_	_	_
33	blue	_	ADJ	_	Degree=Pos	_	_	_	_
34	exclusion	_	NOUN	_	Number=Sing	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	counting	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
39	incorporation	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	AnnexinV	_	ADJ	_	Number=Sing	_	_	_	_
42	labeling	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	by	_	ADP	_	_	_	_	_	_
46	flow	_	NOUN	_	Number=Sing	_	_	_	_
47	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	DNA	_	NOUN	_	Number=Sing	_	_	_	_
50	fragmentation	_	NOUN	_	Number=Sing	_	_	_	_
51	studies	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	hormone	_	NOUN	_	Number=Sing	_	_	_	_
12	receptors	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	since	_	SCONJ	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	estrogen	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	ER	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	ER	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	beta	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
36	receptor	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	PR	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
41	;	_	PUNCT	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	ER	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	alpha	_	NOUN	_	Number=Sing	_	_	_	_
46	protein	_	NOUN	_	Number=Sing	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
49	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
50	by	_	ADP	_	_	_	_	_	_
51	immunocytochemical	_	ADJ	_	Degree=Pos	_	_	_	_
52	analysis	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	hormone	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
7	survival	_	NOUN	_	Number=Sing	_	_	_	_
8	against	_	ADP	_	_	_	_	_	_
9	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	concentration	_	NOUN	_	Number=Sing	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	reaching	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	half	_	ADV	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
19	effect	_	NOUN	_	Number=Sing	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	10	_	NUM	_	NumType=Card	_	_	_	_
22	nM	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	ER	_	NOUN	_	Number=Sing	_	_	_	_
28	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
29	ICI	_	PROPN	_	Number=Sing	_	_	_	_
30	182,780	_	NUM	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	undifferentiated	_	ADJ	_	Degree=Pos	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	further	_	ADV	_	_	_	_	_	_
36	supporting	_	VERB	_	VerbForm=Ger	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	receptor	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
41	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	cell	_	NOUN	_	Number=Sing	_	_	_	_
44	survival	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Other	_	ADJ	_	Degree=Pos	_	_	_	_
2	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	drugs	_	NOUN	_	Number=Plur	_	_	_	_
5	such	_	ADJ	_	Degree=Pos	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	Raloxifene	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	RU486	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	ICI	_	PROPN	_	Number=Sing	_	_	_	_
14	182,780	_	NUM	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	PMA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	displayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	agonist	_	ADJ	_	Degree=Pos	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	SCONJ	_	_	_	_	_	_
24	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
25	TNF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
31	as	_	ADV	_	_	_	_	_	_
32	efficiently	_	ADV	_	_	_	_	_	_
33	as	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	hormones	_	NOUN	_	Number=Plur	_	_	_	_
36	alone	_	ADJ	_	_	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	providing	_	VERB	_	VerbForm=Ger	_	_	_	_
39	further	_	ADJ	_	Degree=Pos	_	_	_	_
40	evidence	_	NOUN	_	Number=Sing	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	notion	_	NOUN	_	Number=Sing	_	_	_	_
44	that	_	SCONJ	_	_	_	_	_	_
45	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
46	receptor	_	NOUN	_	Number=Sing	_	_	_	_
47	drugs	_	NOUN	_	Number=Plur	_	_	_	_
48	may	_	AUX	_	VerbForm=Fin	_	_	_	_
49	manifest	_	VERB	_	VerbForm=Inf	_	_	_	_
50	agonist	_	NOUN	_	Number=Sing	_	_	_	_
51	or	_	CCONJ	_	_	_	_	_	_
52	antagonist	_	NOUN	_	Degree=Pos	_	_	_	_
53	activities	_	NOUN	_	Number=Plur	_	_	_	_
54	depending	_	VERB	_	VerbForm=Ger	_	_	_	_
55	on	_	ADP	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
58	context	_	NOUN	_	Number=Sing	_	_	_	_
59	in	_	ADP	_	_	_	_	_	_
60	which	_	PRON	_	PronType=Rel	_	_	_	_
61	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
62	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
63	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	E2	_	PROPN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	time	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	decrease	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
16	level	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	proapoptotic	_	ADJ	_	Number=Sing	_	_	_	_
20	Nip	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	supporting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	hormone	_	ADJ	_	Number=Sing	_	_	_	_
30	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	U937	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	target	_	NOUN	_	Number=Sing	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	ER	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	PR	_	NOUN	_	Number=Sing	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
17	ligands	_	NOUN	_	Number=Plur	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	impairs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	TNF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	U937	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	presented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	here	_	ADV	_	PronType=Dem	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	female	_	ADJ	_	Degree=Pos	_	_	_	_
9	steroid	_	NOUN	_	Number=Sing	_	_	_	_
10	receptors	_	NOUN	_	Number=Plur	_	_	_	_
11	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	immune	_	ADJ	_	Degree=Pos	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	SCONJ	_	_	_	_	_	_
21	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	monoblastoid	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	;	_	PUNCT	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	effect	_	NOUN	_	Number=Sing	_	_	_	_
29	might	_	AUX	_	VerbForm=Fin	_	_	_	_
30	have	_	VERB	_	VerbForm=Inf	_	_	_	_
31	important	_	ADJ	_	Degree=Pos	_	_	_	_
32	consequences	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
36	use	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
39	receptor	_	NOUN	_	Number=Sing	_	_	_	_
40	drugs	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	--	_	PUNCT	_	_	_	_	_	_
2	Vegeto	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	E.	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	Pollio	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	G.	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	Pellicciari	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	C.	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	Maggi	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	A.	_	PROPN	_	Number=Sing	_	_	_	_
17	Estrogen	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
20	induction	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	survival	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	monoblastoid	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	undergoing	_	VERB	_	VerbForm=Ger	_	_	_	_
27	TNF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	inuced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003251	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Diminished	_	ADJ	_	Degree=Pos	_	_	_	_
2	responses	_	NOUN	_	Number=Plur	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	13	_	NUM	_	NumType=Card	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	differentiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	vitro	_	NOUN	_	Number=Sing	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	role	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	13Ralpha1	_	PROPN	_	Number=Sing	_	_	_	_
20	chain	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	primary	_	ADJ	_	Degree=Pos	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	13	_	NUM	_	NumType=Card	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	complex	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
17	comprised	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	4R	_	PROPN	_	Number=Sing	_	_	_	_
23	alpha	_	PROPN	_	Number=Sing	_	_	_	_
24	chain	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2R	_	PROPN	_	Number=Sing	_	_	_	_
30	gamma	_	NOUN	_	Number=Sing	_	_	_	_
31	chain	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	gamma	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	c	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	like	_	ADP	_	_	_	_	_	_
40	molecule	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	13R	_	NUM	_	NumType=Card	_	_	_	_
45	alpha1	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	13R	_	NUM	_	NumType=Card	_	_	_	_
7	alpha1	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4R	_	PROPN	_	Number=Sing	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	markedly	_	ADV	_	_	_	_	_	_
18	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	vitro	_	ADJ	_	Number=Sing	_	_	_	_
22	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	MDMac	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	with	_	SCONJ	_	_	_	_	_	_
32	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
33	time	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	culture	_	NOUN	_	Number=Sing	_	_	_	_
38	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	loss	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	IL	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	13	_	NUM	_	NumType=Card	_	_	_	_
46	regulation	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	TNF	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	alpha	_	NOUN	_	Number=Sing	_	_	_	_
54	production	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	Daudi	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	THP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	that	_	DET	_	PronType=Rel	_	_	_	_
11	differentially	_	ADV	_	_	_	_	_	_
12	express	_	ADJ	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	c	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	13R	_	NUM	_	Number=Sing	_	_	_	_
21	alpha1	_	NOUN	_	Number=Sing	_	_	_	_
22	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	13	_	NUM	_	NumType=Card	_	_	_	_
27	can	_	AUX	_	VerbForm=Fin	_	_	_	_
28	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
29	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	13R	_	NUM	_	NumType=Card	_	_	_	_
34	alpha1	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	positive	_	ADJ	_	Degree=Pos	_	_	_	_
37	THP	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	but	_	CCONJ	_	_	_	_	_	_
42	not	_	ADV	_	_	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	gamma	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	c	_	NOUN	_	Number=Sing	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	positive	_	ADJ	_	Degree=Pos	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	IL	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	13R	_	NUM	_	NumType=Card	_	_	_	_
54	alpha1	_	NOUN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	negative	_	ADJ	_	Degree=Pos	_	_	_	_
57	Daudi	_	PROPN	_	Number=Sing	_	_	_	_
58	cells	_	NOUN	_	Number=Plur	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	13	_	NUM	_	NumType=Card	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	MDMac	_	PROPN	_	Number=Sing	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	diminished	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	13	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	CD23	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	MHC	_	PROPN	_	Number=Sing	_	_	_	_
26	class	_	NOUN	_	Number=Sing	_	_	_	_
27	II	_	NUM	_	NumType=Card	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	13R	_	NUM	_	NumType=Card	_	_	_	_
8	alpha1	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	low	_	ADJ	_	Degree=Pos	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	STAT6	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	some	_	DET	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	13	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	responses	_	NOUN	_	Number=Plur	_	_	_	_
23	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	unaltered	_	ADJ	_	Degree=Pos	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	MDMac	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	absence	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	functional	_	ADJ	_	Degree=Pos	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	13R	_	NUM	_	NumType=Card	_	_	_	_
9	alpha1	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	c	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	13	_	NUM	_	NumType=Card	_	_	_	_
19	must	_	AUX	_	VerbForm=Fin	_	_	_	_
20	signal	_	VERB	_	VerbForm=Inf	_	_	_	_
21	through	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	complex	_	NOUN	_	Number=Sing	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	MDMac	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Experiments	_	NOUN	_	Number=Plur	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	blocking	_	NOUN	_	Number=Sing	_	_	_	_
5	antibody	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	4R	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	chain	_	NOUN	_	Number=Sing	_	_	_	_
15	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	essential	_	ADJ	_	Degree=Pos	_	_	_	_
18	component	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	13	_	NUM	_	NumType=Card	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	complex	_	NOUN	_	Number=Sing	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	MDMac	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003255	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	RanBP1	_	PROPN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	release	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	CRM1	_	NOUN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	pore	_	NOUN	_	Number=Sing	_	_	_	_
14	complex	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
18	step	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	export	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	recently	_	ADV	_	_	_	_	_	_
3	developed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	assay	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	export	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	shuttling	_	VERB	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	can	_	AUX	_	VerbForm=Fin	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	reconstituted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	permeabilized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	GTPase	_	NOUN	_	Number=Sing	_	_	_	_
33	Ran	_	PROPN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
37	export	_	NOUN	_	Number=Sing	_	_	_	_
38	receptor	_	NOUN	_	Number=Sing	_	_	_	_
39	CRM1	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	now	_	ADV	_	_	_	_	_	_
4	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	assay	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
9	another	_	DET	_	_	_	_	_	_
10	export	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	preincubation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	permeabilized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	Ran	_	PROPN	_	Number=Sing	_	_	_	_
9	mutant	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	can	_	AUX	_	VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	hydrolyze	_	VERB	_	VerbForm=Inf	_	_	_	_
14	GTP	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	RanQ69L	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
20	supports	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	NFAT	_	ADJ	_	Degree=Pos	_	_	_	_
22	export	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	CRM1	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	Ran	_	PROPN	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	alone	_	ADV	_	_	_	_	_	_
29	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	not	_	PART	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	RanQ69L	_	PROPN	_	Number=Sing	_	_	_	_
3	preincubation	_	NOUN	_	Number=Sing	_	_	_	_
4	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	CRM1	_	NOUN	_	Number=Sing	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
12	periphery	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	pore	_	NOUN	_	Number=Sing	_	_	_	_
17	complex	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	NPC	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	association	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	p62	_	NOUN	_	Number=Sing	_	_	_	_
26	complex	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	Can	_	PROPN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	Nup214	_	PROPN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	RanGTP	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	association	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CRM1	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	nucleoporins	_	NOUN	_	Number=Plur	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	reconstituted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vitro	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
3	fractionation	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	reconstitution	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	RanBP1	_	PROPN	_	Number=Sing	_	_	_	_
11	restores	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	export	_	NOUN	_	Number=Sing	_	_	_	_
14	after	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	RanQ69L	_	PROPN	_	Number=Sing	_	_	_	_
17	preincubation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	export	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	preincubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	RanQ69L	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	RanBP1	_	PROPN	_	Number=Sing	_	_	_	_
2	as	_	ADV	_	_	_	_	_	_
3	well	_	ADV	_	Degree=Pos	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	Ran	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	domains	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
12	nucleoporin	_	NOUN	_	Number=Sing	_	_	_	_
13	RanBP2	_	PROPN	_	Number=Sing	_	_	_	_
14	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	release	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	CRM1	_	NOUN	_	Number=Sing	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	NPC	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	RanGTP	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	targeting	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	export	_	NOUN	_	Number=Sing	_	_	_	_
16	complexes	_	NOUN	_	Number=Plur	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
20	side	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	NPC	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	that	_	DET	_	_	_	_	_	_
26	RanBP1	_	PROPN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	probably	_	ADV	_	_	_	_	_	_
29	RanBP2	_	PROPN	_	Number=Sing	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	involved	_	ADJ	_	Degree=Pos	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
37	export	_	NOUN	_	Number=Sing	_	_	_	_
38	complexes	_	NOUN	_	Number=Plur	_	_	_	_
39	from	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	NPC	_	PROPN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
45	step	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	transport	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003265	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	1,25	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_

1	D3	_	PROPN	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	RNA	_	PROPN	_	Number=Sing	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	1,25	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Dihydroxyvitamin	_	PROPN	_	Number=Sing	_	_	_	_
4	D3	_	NOUN	_	Number=Sing	_	_	_	_
5	[	_	PUNCT	_	_	_	_	_	_
6	1,25	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	OH	_	NOUN	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	2D3	_	NUM	_	Number=Sing	_	_	_	_
11	]	_	PUNCT	_	_	_	_	_	_
12	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	inhibits	_	VERB	_	Degree=Pos	_	_	_	_
16	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
19	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	various	_	ADJ	_	Degree=Pos	_	_	_	_
23	lines	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	patients	_	NOUN	_	Number=Plur	_	_	_	_
26	;	_	PUNCT	_	_	_	_	_	_
27	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
28	effects	_	NOUN	_	Number=Plur	_	_	_	_
29	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	probably	_	ADV	_	_	_	_	_	_
31	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	through	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	1,25	_	NUM	_	NumType=Card	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	OH	_	INTJ	_	_	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	2D3	_	NUM	_	NumType=Card	_	_	_	_
39	receptor	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Little	_	ADV	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	1,25	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	OH	_	INTJ	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	2D3	_	NUM	_	NumType=Card	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	RNA	_	PROPN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	modulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	1,25	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	OH	_	INTJ	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	2D3	_	NUM	_	NumType=Card	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	RNA	_	PROPN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	various	_	ADJ	_	Degree=Pos	_	_	_	_
19	proliferating	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	nonproliferating	_	VERB	_	Degree=Pos	_	_	_	_
22	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	1,25	_	NUM	_	NumType=Card	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	OH	_	INTJ	_	_	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	2D3	_	NUM	_	NumType=Card	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	RNA	_	PROPN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	various	_	ADJ	_	Degree=Pos	_	_	_	_
15	kinds	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	including	_	VERB	_	VerbForm=Ger	_	_	_	_
21	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	as	_	ADV	_	_	_	_	_	_
28	well	_	ADV	_	Degree=Pos	_	_	_	_
29	as	_	ADP	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	lines	_	NOUN	_	Number=Plur	_	_	_	_
33	KG	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	myeloblasts	_	NOUN	_	Number=Plur	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	HL	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	60	_	NUM	_	NumType=Card	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	promyelocytes	_	NOUN	_	Number=Plur	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	ML	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	3	_	NUM	_	NumType=Card	_	_	_	_
50	(	_	PUNCT	_	_	_	_	_	_
51	myelomonoblasts	_	NOUN	_	Number=Plur	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	U937	_	NOUN	_	Number=Sing	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	THP	_	NOUN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	1	_	NUM	_	NumType=Card	_	_	_	_
59	(	_	PUNCT	_	_	_	_	_	_
60	monoblasts	_	NOUN	_	Number=Plur	_	_	_	_
61	)	_	PUNCT	_	_	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	K562	_	NOUN	_	Number=Sing	_	_	_	_
64	(	_	PUNCT	_	_	_	_	_	_
65	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
66	)	_	PUNCT	_	_	_	_	_	_
67	,	_	PUNCT	_	_	_	_	_	_
68	and	_	CCONJ	_	_	_	_	_	_
69	S	_	PROPN	_	Number=Sing	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	LB1	_	PROPN	_	Number=Sing	_	_	_	_
72	(	_	PUNCT	_	_	_	_	_	_
73	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
74	-	_	PUNCT	_	_	_	_	_	_
75	1	_	NUM	_	NumType=Card	_	_	_	_
76	-	_	PUNCT	_	_	_	_	_	_
77	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
78	T	_	NOUN	_	Number=Sing	_	_	_	_
79	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
80	)	_	PUNCT	_	_	_	_	_	_
81	.	_	PUNCT	_	_	_	_	_	_

1	Receptor	_	NOUN	_	Number=Sing	_	_	_	_
2	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	4.6	_	NUM	_	NumType=Card	_	_	_	_
5	kilobases	_	NOUN	_	Number=Plur	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	kb	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	no	_	DET	_	_	_	_	_	_
12	variant	_	ADJ	_	Degree=Pos	_	_	_	_
13	sizes	_	NOUN	_	Number=Plur	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	group	_	NOUN	_	Number=Sing	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	1,25	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	OH	_	INTJ	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	2D3	_	NUM	_	NumType=Card	_	_	_	_
15	receptors	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Most	_	ADJ	_	_	_	_	_	_
2	B	_	ADJ	_	Degree=Pos	_	_	_	_
3	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	negligible	_	ADJ	_	Degree=Pos	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	1,25	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	OH	_	NOUN	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	2D3	_	NUM	_	NumType=Card	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	RNA	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	;	_	PUNCT	_	_	_	_	_	_
19	however	_	ADV	_	_	_	_	_	_
20	;	_	PUNCT	_	_	_	_	_	_
21	analysis	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
27	somatic	_	ADJ	_	Degree=Pos	_	_	_	_
28	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
29	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	that	_	SCONJ	_	_	_	_	_	_
31	suppression	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	1,25	_	NUM	_	NumType=Card	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	OH	_	INTJ	_	_	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	2D3	_	NUM	_	NumType=Card	_	_	_	_
40	receptor	_	NOUN	_	Number=Sing	_	_	_	_
41	RNA	_	PROPN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	B	_	ADJ	_	Degree=Pos	_	_	_	_
44	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
45	may	_	AUX	_	VerbForm=Fin	_	_	_	_
46	be	_	AUX	_	VerbForm=Inf	_	_	_	_
47	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
48	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
49	characteristic	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	HL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	60	_	NUM	_	NumType=Card	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	cultured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	10	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	-	_	SYM	_	_	_	_	_	_
11	7	_	NUM	_	NumType=Card	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	mol	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	L	_	SYM	_	Number=Sing	_	_	_	_
16	1,25	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	OH	_	NOUN	_	_	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	2D3	_	NUM	_	NumType=Card	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	24	_	NUM	_	NumType=Card	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	72	_	NUM	_	NumType=Card	_	_	_	_
25	hours	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	levels	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	1,25	_	NUM	_	NumType=Card	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	OH	_	INTJ	_	_	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	2D3	_	NUM	_	NumType=Card	_	_	_	_
37	receptor	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
40	RNA	_	PROPN	_	Number=Sing	_	_	_	_
41	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
42	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Levels	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	RNA	_	PROPN	_	Number=Sing	_	_	_	_
4	coding	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	exposure	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	high	_	ADJ	_	Degree=Pos	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	ligand	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Levels	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	occupied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	1,25	_	NUM	_	NumType=Card	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	OH	_	INTJ	_	_	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	2D3	_	NUM	_	NumType=Card	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	HL	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	60	_	NUM	_	NumType=Card	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	;	_	PUNCT	_	_	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	total	_	ADJ	_	Degree=Pos	_	_	_	_
22	number	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	1,25	_	NUM	_	NumType=Card	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	OH	_	INTJ	_	_	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	2D3	_	NUM	_	NumType=Card	_	_	_	_
29	receptors	_	NOUN	_	Number=Plur	_	_	_	_
30	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	about	_	ADV	_	_	_	_	_	_
32	50	_	NUM	_	NumType=Card	_	_	_	_
33	%	_	SYM	_	Number=Sing	_	_	_	_
34	at	_	ADP	_	_	_	_	_	_
35	24	_	NUM	_	NumType=Card	_	_	_	_
36	hours	_	NOUN	_	Number=Plur	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	returned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
39	toward	_	ADP	_	_	_	_	_	_
40	normal	_	ADJ	_	Degree=Pos	_	_	_	_
41	at	_	ADP	_	_	_	_	_	_
42	72	_	NUM	_	NumType=Card	_	_	_	_
43	hours	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Steady	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	state	_	NOUN	_	Number=Sing	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	1,25	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	OH	_	INTJ	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	2D3	_	NUM	_	NumType=Card	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	RNA	_	PROPN	_	Number=Sing	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	HL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	SYM	_	_	_	_	_	_
22	60	_	NUM	_	NumType=Card	_	_	_	_
23	toward	_	ADP	_	_	_	_	_	_
24	either	_	CCONJ	_	_	_	_	_	_
25	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Nondividing	_	ADJ	_	Number=Sing	_	_	_	_
2	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	normal	_	ADJ	_	Degree=Pos	_	_	_	_
5	individuals	_	NOUN	_	Number=Plur	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	1,25	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	OH	_	INTJ	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	2D3	_	NUM	_	NumType=Card	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	RNA	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	nondividing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	normal	_	ADJ	_	Degree=Pos	_	_	_	_
10	individuals	_	NOUN	_	Number=Plur	_	_	_	_
11	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	express	_	VERB	_	VerbForm=Inf	_	_	_	_
14	1,25	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	OH	_	INTJ	_	_	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	2D3	_	NUM	_	NumType=Card	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	RNA	_	NOUN	_	Number=Sing	_	_	_	_
21	;	_	PUNCT	_	_	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	1,25	_	NUM	_	NumType=Card	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	OH	_	NOUN	_	_	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	2D3	_	NUM	_	NumType=Card	_	_	_	_
37	receptor	_	NOUN	_	Number=Sing	_	_	_	_
38	RNA	_	PROPN	_	Number=Sing	_	_	_	_
39	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	markedly	_	ADV	_	_	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Half	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	life	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	t1/2	_	NOUN	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	1,25	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	OH	_	NOUN	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	D3	_	NOUN	_	Number=Sing	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	RNA	_	PROPN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	short	_	ADJ	_	Degree=Pos	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	hour	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	as	_	SCONJ	_	_	_	_	_	_
26	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	SCONJ	_	_	_	_	_	_
28	measuring	_	VERB	_	VerbForm=Ger	_	_	_	_
29	decay	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	message	_	NOUN	_	Number=Sing	_	_	_	_
33	after	_	ADP	_	_	_	_	_	_
34	addition	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	actinomycin	_	NOUN	_	Number=Sing	_	_	_	_
37	D.	_	PROPN	_	Number=Sing	_	_	_	_
38	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
41	short	_	ADJ	_	Degree=Pos	_	_	_	_
42	t1	_	NOUN	_	Number=Sing	_	_	_	_
43	/	_	PUNCT	_	_	_	_	_	_
44	2	_	NUM	_	NumType=Card	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	1,25	_	NUM	_	NumType=Card	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	OH	_	INTJ	_	_	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	2D3	_	NUM	_	NumType=Card	_	_	_	_
53	receptor	_	NOUN	_	Number=Sing	_	_	_	_
54	RNA	_	PROPN	_	Number=Sing	_	_	_	_
55	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
56	in	_	ADP	_	_	_	_	_	_
57	cells	_	NOUN	_	Number=Plur	_	_	_	_
58	as	_	SCONJ	_	_	_	_	_	_
59	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
60	protein	_	NOUN	_	Number=Sing	_	_	_	_
61	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
62	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
63	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	physiologic	_	ADJ	_	Degree=Pos	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	1,25	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	OH	_	INTJ	_	_	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	2D3	_	NUM	_	NumType=Card	_	_	_	_
16	receptors	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	proliferating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003267	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	induces	_	NOUN	_	Number=Plur	_	_	_	_
5	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	translocation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	stat3	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	early	_	ADJ	_	Degree=Pos	_	_	_	_
3	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
4	event	_	NOUN	_	Number=Sing	_	_	_	_
5	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	through	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2R	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	tyrosine	_	ADJ	_	Degree=Pos	_	_	_	_
23	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	several	_	ADJ	_	Degree=Pos	_	_	_	_
26	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
27	substrates	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	exact	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	regulates	_	VERB	_	Number=Plur	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	different	_	ADJ	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	presently	_	ADV	_	_	_	_	_	_
16	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	DET	_	_	_	_	_	_
6	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	through	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2R	_	NOUN	_	Number=Sing	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
14	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	translocation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	stat3	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	newly	_	ADV	_	_	_	_	_	_
24	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	member	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	signal	_	NOUN	_	Number=Sing	_	_	_	_
29	transducers	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	activators	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	STAT	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	family	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	proteins	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	stat1	_	NOUN	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
9	phosphorylated	_	VERB	_	Number=Sing	_	_	_	_
10	after	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	ligation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	whereas	_	SCONJ	_	_	_	_	_	_
17	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	stat1	_	NOUN	_	Number=Sing	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	91	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	84	_	NUM	_	NumType=Card	_	_	_	_
26	kDa	_	NOUN	_	Number=Sing	_	_	_	_
27	proteins	_	NOUN	_	Number=Plur	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	translocated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
34	following	_	VERB	_	VerbForm=Ger	_	_	_	_
35	interferon	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	gamma	_	NOUN	_	Number=Sing	_	_	_	_
38	treatment	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Apart	_	ADV	_	_	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	stat3	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	another	_	DET	_	_	_	_	_	_
6	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	tyrosine	_	ADJ	_	Degree=Pos	_	_	_	_
10	phosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	subsequently	_	ADV	_	_	_	_	_	_
13	translocated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
6	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
7	mass	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	84	_	NUM	_	NumType=Card	_	_	_	_
10	kDa	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	stat3	_	NOUN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	stat1	_	NOUN	_	Number=Sing	_	_	_	_
19	mAb	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	antisera	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	translocation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	84	_	NUM	_	NumType=Card	_	_	_	_
11	kDa	_	PROPN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	stat3	_	NOUN	_	Number=Sing	_	_	_	_
15	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	identical	_	ADJ	_	Degree=Pos	_	_	_	_
17	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	p84	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	candidate	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	new	_	ADJ	_	Degree=Pos	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	yet	_	ADV	_	_	_	_	_	_
28	undefined	_	ADJ	_	Degree=Pos	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	member	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	STAT	_	PROPN	_	Number=Sing	_	_	_	_
34	family	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	induces	_	NOUN	_	Number=Plur	_	_	_	_
11	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
12	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	translocation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	stat3	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	as	_	SCONJ	_	_	_	_	_	_
22	yet	_	ADV	_	_	_	_	_	_
23	undefined	_	ADJ	_	Degree=Pos	_	_	_	_
24	84	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kDa	_	NOUN	_	Number=Sing	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	antigen	_	ADJ	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	specific	_	ADJ	_	Degree=Pos	_	_	_	_
32	human	_	ADJ	_	Degree=Pos	_	_	_	_
33	T	_	NOUN	_	Number=Sing	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	lines	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003268	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	via	_	ADP	_	_	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	Raf	_	NOUN	_	Number=Sing	_	_	_	_
14	kinase	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
17	+	_	SYM	_	_	_	_	_	_
18	influx	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	synergy	_	NOUN	_	Number=Sing	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	Raf	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	Signals	_	NOUN	_	Number=Plur	_	_	_	_
2	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	via	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	TCR	_	NOUN	_	Number=Sing	_	_	_	_
6	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	turn	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	critical	_	ADJ	_	Degree=Pos	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
30	induction	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	many	_	ADJ	_	Degree=Pos	_	_	_	_
33	genes	_	NOUN	_	Number=Plur	_	_	_	_
34	important	_	ADJ	_	Degree=Pos	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	differentiated	_	ADJ	_	Degree=Pos	_	_	_	_
43	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	C	_	PROPN	_	Number=Sing	_	_	_	_
10	activator	_	NOUN	_	Number=Sing	_	_	_	_
11	PMA	_	PROPN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	combination	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_
17	ionophores	_	NOUN	_	Number=Plur	_	_	_	_
18	mimics	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	process	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	two	_	NUM	_	NumType=Card	_	_	_	_
25	agents	_	NOUN	_	Number=Plur	_	_	_	_
26	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	often	_	ADV	_	_	_	_	_	_
28	substituted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	TCR	_	NOUN	_	Number=Sing	_	_	_	_
31	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	bypassing	_	VERB	_	VerbForm=Ger	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	TCR	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	signaling	_	NOUN	_	Number=Sing	_	_	_	_
6	components	_	NOUN	_	Number=Plur	_	_	_	_
7	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	following	_	VERB	_	VerbForm=Ger	_	_	_	_
15	TCR	_	NOUN	_	Number=Sing	_	_	_	_
16	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	TCR	_	NOUN	_	Number=Sing	_	_	_	_
2	signaling	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	triggered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	SCONJ	_	_	_	_	_	_
6	treating	_	VERB	_	VerbForm=Ger	_	_	_	_
7	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	PHA	_	NOUN	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
14	Abs	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	monitored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
25	mobility	_	NOUN	_	Number=Sing	_	_	_	_
26	shift	_	NOUN	_	Number=Sing	_	_	_	_
27	assays	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
35	reporter	_	NOUN	_	Number=Sing	_	_	_	_
36	assays	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Contrary	_	ADJ	_	Degree=Pos	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	idea	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	protein	_	VERB	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	C	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	involved	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	TCR	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	VERB	_	Degree=Pos	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	high	_	ADJ	_	Degree=Pos	_	_	_	_
22	doses	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	staurosporine	_	NOUN	_	Number=Sing	_	_	_	_
25	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	interfere	_	VERB	_	VerbForm=Inf	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	PHA	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	while	_	SCONJ	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	same	_	ADJ	_	Degree=Pos	_	_	_	_
40	dose	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	staurosporine	_	NOUN	_	Number=Sing	_	_	_	_
43	completely	_	ADV	_	_	_	_	_	_
44	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	by	_	ADP	_	_	_	_	_	_
47	PMA	_	PROPN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	PHA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	reporter	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	however	_	ADV	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	effectively	_	ADV	_	_	_	_	_	_
14	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
18	negative	_	ADJ	_	Degree=Pos	_	_	_	_
19	form	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	Raf	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	critical	_	ADJ	_	Degree=Pos	_	_	_	_
28	role	_	NOUN	_	Number=Sing	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	Raf	_	PROPN	_	Number=Sing	_	_	_	_
32	kinase	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	TCR	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_
17	influx	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	because	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
22	+	_	SYM	_	_	_	_	_	_
23	channel	_	NOUN	_	Number=Sing	_	_	_	_
24	blocker	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	SK&F	_	PROPN	_	Number=Sing	_	_	_	_
27	96365	_	NUM	_	NumType=Card	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	as	_	ADV	_	_	_	_	_	_
30	well	_	ADV	_	Degree=Pos	_	_	_	_
31	as	_	ADP	_	_	_	_	_	_
32	other	_	ADJ	_	Degree=Pos	_	_	_	_
33	agents	_	NOUN	_	Number=Plur	_	_	_	_
34	that	_	PRON	_	PronType=Rel	_	_	_	_
35	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
38	+	_	SYM	_	_	_	_	_	_
39	influx	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	NF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	constitutively	_	ADV	_	_	_	_	_	_
5	active	_	ADJ	_	Degree=Pos	_	_	_	_
6	form	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
9	largely	_	ADV	_	_	_	_	_	_
10	substituted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
14	+	_	SYM	_	_	_	_	_	_
15	requirement	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	reversed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	blockade	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	SK&F	_	PROPN	_	Number=Sing	_	_	_	_
22	96365	_	NUM	_	NumType=Card	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	observations	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	coexpression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	constitutively	_	ADV	_	_	_	_	_	_
9	active	_	ADJ	_	Degree=Pos	_	_	_	_
10	forms	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Raf	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
17	synergistically	_	ADV	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	reporter	_	NOUN	_	Number=Sing	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	physiologically	_	ADV	_	_	_	_	_	_
28	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
29	functional	_	ADJ	_	Degree=Pos	_	_	_	_
30	interaction	_	NOUN	_	Number=Sing	_	_	_	_
31	between	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	kinase	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003270	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	after	_	ADP	_	_	_	_	_	_
10	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
14	blood	_	NOUN	_	Number=Sing	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	through	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	surface	_	NOUN	_	Number=Sing	_	_	_	_
20	ganglioside	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	GD3	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	[	_	PUNCT	_	_	_	_	_	_
25	published	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	erratum	_	NOUN	_	Number=Sing	_	_	_	_
27	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	J	_	PROPN	_	Number=Sing	_	_	_	_
30	Immunol	_	PROPN	_	Number=Sing	_	_	_	_
31	1994	_	NUM	_	NumType=Card	_	_	_	_
32	Jul	_	PROPN	_	Number=Sing	_	_	_	_
33	15	_	NUM	_	NumType=Card	_	_	_	_
34	;	_	PUNCT	_	_	_	_	_	_
35	153	_	NUM	_	NumType=Card	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	2):910	_	NUM	_	NumType=Card	_	_	_	_
38	]	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	gangliosides	_	NOUN	_	Number=Plur	_	_	_	_
7	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	signaling	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	recognition	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	function	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	processes	_	NOUN	_	Number=Plur	_	_	_	_
9	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	clearly	_	ADV	_	_	_	_	_	_
13	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	mAb	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	R24	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	reacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	specifically	_	ADV	_	_	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	surface	_	NOUN	_	Number=Sing	_	_	_	_
13	ganglioside	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	GD3	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
19	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	T	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
30	blood	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	R24	_	PROPN	_	Number=Sing	_	_	_	_
14	mAb	_	NOUN	_	Number=Sing	_	_	_	_
15	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	T	_	NOUN	_	NumType=Card	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	functions	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	R24	_	PROPN	_	Number=Sing	_	_	_	_
7	mAb	_	NOUN	_	Number=Sing	_	_	_	_
8	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	GD3	_	PROPN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_

1	T	_	NUM	_	NumType=Card	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	surface	_	NOUN	_	Number=Sing	_	_	_	_
9	marker	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2R	_	NOUN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	chain	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2R	_	NUM	_	Number=Sing	_	_	_	_
22	beta-chain	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	HLA	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	DR	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	CD11a	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	CD11c	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IFN	_	ADJ	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	gamma	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	but	_	CCONJ	_	_	_	_	_	_
8	not	_	ADV	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	4	_	NUM	_	NumType=Card	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	present	_	ADJ	_	Degree=Pos	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	culture	_	NOUN	_	Number=Sing	_	_	_	_
26	supernatants	_	NOUN	_	Number=Plur	_	_	_	_
27	72	_	NUM	_	NumType=Card	_	_	_	_
28	h	_	NOUN	_	Number=Plur	_	_	_	_
29	after	_	ADP	_	_	_	_	_	_
30	R24	_	NUM	_	Number=Sing	_	_	_	_
31	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	some	_	DET	_	_	_	_	_	_
3	donors	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	TNF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	after	_	ADP	_	_	_	_	_	_
18	R24	_	NUM	_	Number=Sing	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	R24	_	NUM	_	Number=Sing	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	translocation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	little	_	ADJ	_	Degree=Pos	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	no	_	DET	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	p50	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	p65	_	NUM	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	increase	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	binding	_	NOUN	_	Number=Sing	_	_	_	_
36	complexes	_	NOUN	_	Number=Plur	_	_	_	_
37	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
38	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	p50	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	substrates	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	R24	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	increases	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	surface	_	NOUN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	could	_	AUX	_	VerbForm=Fin	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	staurosporin	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	cyclophilin	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	C	_	PROPN	_	Number=Sing	_	_	_	_
32	may	_	AUX	_	VerbForm=Fin	_	_	_	_
33	be	_	AUX	_	VerbForm=Inf	_	_	_	_
34	involved	_	ADJ	_	Degree=Pos	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	R24	_	PROPN	_	Number=Sing	_	_	_	_
38	signaling	_	NOUN	_	Number=Sing	_	_	_	_
39	pathway	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	herbimycin	_	NOUN	_	Number=Sing	_	_	_	_
4	A	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	R24	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	increase	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
22	at	_	ADP	_	_	_	_	_	_
23	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
24	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	specificity	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
29	kinases	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
6	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
7	pathways	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	involved	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	R24	_	NUM	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003272	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	ATp	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	hallmark	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
10	B	_	ADJ	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	B	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	CLL	_	ADJ	_	Number=Sing	_	_	_	_
16	patients	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	B	_	NOUN	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	patients	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
11	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	leukaemia	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	CLL	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	analysed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	presence	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	DNA	_	NOUN	_	Number=Sing	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	panel	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factors	_	NOUN	_	Number=Plur	_	_	_	_
31	which	_	PRON	_	PronType=Rel	_	_	_	_
32	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	involved	_	ADJ	_	Degree=Pos	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	control	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	following	_	VERB	_	VerbForm=Ger	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	:	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Octamer	_	PROPN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	Oct	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	Oct	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	members	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	AP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	family	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	AT	_	ADP	_	_	_	_	_	_
31	factors	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	particular	_	ADJ	_	Degree=Pos	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	ATp	_	PROPN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	members	_	NOUN	_	Number=Plur	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	Rel	_	PROPN	_	Number=Sing	_	_	_	_
44	/	_	PUNCT	_	_	_	_	_	_
45	NF	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	kB	_	PROPN	_	Number=Sing	_	_	_	_
48	family	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	translocation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	ATp	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	member	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	growing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	family	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	AT	_	ADP	_	_	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	hallmark	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	nonstimulated	_	VERB	_	Degree=Pos	_	_	_	_
30	B	_	ADJ	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	CLL	_	PROPN	_	Number=Sing	_	_	_	_
34	patients	_	NOUN	_	Number=Plur	_	_	_	_
35	that	_	PRON	_	PronType=Rel	_	_	_	_
36	distinguishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	B	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	CLL	_	NOUN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	from	_	ADP	_	_	_	_	_	_
42	'	_	PUNCT	_	_	_	_	_	_
43	normal	_	ADJ	_	Degree=Pos	_	_	_	_
44	'	_	PUNCT	_	_	_	_	_	_
45	B	_	NOUN	_	Number=Sing	_	_	_	_
46	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	appearance	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kB2/p52	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	further	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	proteins	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	DNA	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	such	_	ADJ	_	Degree=Pos	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	JunD	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	c	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	Fos	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	FosB	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	several	_	ADJ	_	Degree=Pos	_	_	_	_
24	patients	_	NOUN	_	Number=Plur	_	_	_	_
25	whereas	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	localisation	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	DNA	_	NOUN	_	Number=Sing	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	other	_	ADJ	_	Degree=Pos	_	_	_	_
33	factors	_	NOUN	_	Number=Plur	_	_	_	_
34	such	_	ADJ	_	Degree=Pos	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	c-Jun	_	PROPN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	RelA	_	PROPN	_	Number=Sing	_	_	_	_
39	/	_	PUNCT	_	_	_	_	_	_
40	p65	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	c	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	Rel	_	NOUN	_	Number=Sing	_	_	_	_
45	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
46	unaltered	_	ADJ	_	Degree=Pos	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	remarkable	_	ADJ	_	Degree=Pos	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	B	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	CLL	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	appearance	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	DNA	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factors	_	NOUN	_	Number=Plur	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	dramatically	_	ADV	_	_	_	_	_	_
22	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	whereas	_	SCONJ	_	_	_	_	_	_
24	other	_	ADJ	_	Degree=Pos	_	_	_	_
25	members	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	same	_	ADJ	_	Degree=Pos	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	family	_	NOUN	_	Number=Sing	_	_	_	_
31	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	unaltered	_	ADJ	_	Degree=Pos	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
35	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	which	_	DET	_	PronType=Int	_	_	_	_
7	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
8	events	_	NOUN	_	Number=Plur	_	_	_	_
9	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	'	_	PUNCT	_	_	_	_	_	_
14	pre-activation	_	NOUN	_	Number=Sing	_	_	_	_
15	'	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	i.e.	_	X	_	_	_	_	_	_
18	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	translocation	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	DNA	_	NOUN	_	Number=Sing	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
27	members	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	AT	_	ADP	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kB	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	AP	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	factor	_	NOUN	_	Number=Sing	_	_	_	_
41	families	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003277	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	MDS1	_	PROPN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	EVI1	_	PROPN	_	Number=Sing	_	_	_	_
4	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	TGF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	beta1	_	NOUN	_	Number=Sing	_	_	_	_
8	signaling	_	VERB	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	strengthens	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
15	effect	_	NOUN	_	Number=Sing	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	fusion	_	NOUN	_	Number=Sing	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	AML1	_	PROPN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	MDS1	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	EVI1	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	product	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	t(3;21	_	NUM	_	NumType=Card	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	abrogates	_	VERB	_	Degree=Pos	_	_	_	_
36	growth	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	response	_	NOUN	_	Number=Sing	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	TGF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	beta1	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	MDS1	_	PROPN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	EVI1	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	band	_	NOUN	_	Number=Sing	_	_	_	_
10	q26	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	zinc	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	finger	_	NOUN	_	Number=Sing	_	_	_	_
17	DNA	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	binding	_	VERB	_	Number=Sing	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	activator	_	NOUN	_	Number=Sing	_	_	_	_
22	not	_	ADV	_	_	_	_	_	_
23	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	normal	_	ADJ	_	Degree=Pos	_	_	_	_
26	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	but	_	CCONJ	_	_	_	_	_	_
29	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	several	_	ADJ	_	Degree=Pos	_	_	_	_
32	normal	_	ADJ	_	Degree=Pos	_	_	_	_
33	tissues	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	MDS1	_	PROPN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	EVI1	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	inappropriately	_	ADV	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
9	leukemias	_	NOUN	_	Number=Plur	_	_	_	_
10	following	_	VERB	_	VerbForm=Ger	_	_	_	_
11	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
12	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
13	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
14	band	_	NOUN	_	Number=Sing	_	_	_	_
15	3q26	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
3	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	either	_	ADV	_	_	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	gene	_	VERB	_	Number=Sing	_	_	_	_
7	truncation	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	repressor	_	NOUN	_	Number=Sing	_	_	_	_
16	EVI1	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	as	_	SCONJ	_	_	_	_	_	_
19	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	t(3;3	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	q21;q26	_	NUM	_	NumType=Card	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	inv	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	q21q26	_	NUM	_	NumType=Card	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	or	_	CCONJ	_	_	_	_	_	_
37	to	_	PART	_	_	_	_	_	_
38	gene	_	VERB	_	Number=Sing	_	_	_	_
39	fusion	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	as	_	SCONJ	_	_	_	_	_	_
42	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	t(3;21	_	NUM	_	NumType=Card	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	q26;q22	_	NUM	_	NumType=Card	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	which	_	DET	_	PronType=Rel	_	_	_	_
51	results	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	fusion	_	NOUN	_	Number=Sing	_	_	_	_
55	protein	_	NOUN	_	Number=Sing	_	_	_	_
56	AML1	_	NOUN	_	Number=Sing	_	_	_	_
57	/	_	PUNCT	_	_	_	_	_	_
58	MDS1/EVI1	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	fusion	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	domain	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	AML1	_	PROPN	_	Number=Sing	_	_	_	_
15	fused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	frame	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	entire	_	ADJ	_	Degree=Pos	_	_	_	_
22	MDS1	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	EVI1	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	exclusion	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
30	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
31	12	_	NUM	_	NumType=Card	_	_	_	_
32	amino	_	NOUN	_	Number=Sing	_	_	_	_
33	acids	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	response	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
13	precursor	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	line	_	NOUN	_	Number=Sing	_	_	_	_
16	32Dcl3	_	NOUN	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	either	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	normal	_	ADJ	_	Degree=Pos	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	MDS1	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	EVI1	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	fusion	_	NOUN	_	Number=Sing	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	AML1	_	NOUN	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	MDS1	_	NOUN	_	Number=Sing	_	_	_	_
33	/	_	PUNCT	_	_	_	_	_	_
34	EVI1	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	factors	_	NOUN	_	Number=Plur	_	_	_	_
38	that	_	DET	_	PronType=Rel	_	_	_	_
39	control	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
42	or	_	CCONJ	_	_	_	_	_	_
43	cell	_	NOUN	_	Number=Sing	_	_	_	_
44	replication	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	32Dcl3	_	NUM	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	3	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	growth	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
14	differentiate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	into	_	ADP	_	_	_	_	_	_
16	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	when	_	ADV	_	PronType=Int	_	_	_	_
18	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	G	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	CSF	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	growth	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	TGF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	beta1	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	whereas	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	MDS1	_	PROPN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	EVI1	_	PROPN	_	Number=Sing	_	_	_	_
11	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	no	_	DET	_	_	_	_	_	_
13	effect	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	G	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	CSF	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	AML1	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	MDS1	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	EVI1	_	NOUN	_	Number=Sing	_	_	_	_
30	blocks	_	NOUN	_	Number=Plur	_	_	_	_
31	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
32	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	death	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	similar	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
7	previously	_	ADV	_	_	_	_	_	_
8	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	others	_	NOUN	_	Number=Plur	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	32	_	NUM	_	NumType=Card	_	_	_	_
13	Dcl3	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
18	Evil	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	whereas	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	fusion	_	NOUN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	AML1	_	PROPN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	MDS1	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	EVI1	_	PROPN	_	Number=Sing	_	_	_	_
18	completely	_	ADV	_	_	_	_	_	_
19	abrogates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	growth	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
24	effect	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	TGF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	beta1	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	allows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	32	_	NUM	_	NumType=Card	_	_	_	_
32	Dcl3	_	NOUN	_	Degree=Pos	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	proliferate	_	VERB	_	VerbForm=Inf	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	expression	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	normal	_	ADJ	_	Degree=Pos	_	_	_	_
41	protein	_	NOUN	_	Number=Sing	_	_	_	_
42	MDS1	_	NOUN	_	Number=Sing	_	_	_	_
43	/	_	PUNCT	_	_	_	_	_	_
44	EVI1	_	PROPN	_	Number=Sing	_	_	_	_
45	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	opposite	_	ADJ	_	Degree=Pos	_	_	_	_
48	effect	_	NOUN	_	Number=Sing	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
52	strengthens	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	response	_	NOUN	_	Number=Sing	_	_	_	_
55	of	_	ADP	_	_	_	_	_	_
56	cells	_	NOUN	_	Number=Plur	_	_	_	_
57	to	_	ADP	_	_	_	_	_	_
58	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
59	growth	_	NOUN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
62	effect	_	NOUN	_	Number=Sing	_	_	_	_
63	of	_	ADP	_	_	_	_	_	_
64	TGF	_	PROPN	_	Number=Sing	_	_	_	_
65	-	_	PUNCT	_	_	_	_	_	_
66	beta1	_	NOUN	_	Number=Sing	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	yeast	_	ADJ	_	Number=Sing	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
8	system	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	EVI1	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	entirety	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	MDS1	_	PROPN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	EVI1	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	AML1	_	PROPN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	MDS1	_	PROPN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	EVI1	_	PROPN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	physically	_	ADV	_	_	_	_	_	_
32	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	SMAD3	_	PROPN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	which	_	PRON	_	PronType=Rel	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
40	mediator	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	TGF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	beta1	_	NOUN	_	Number=Sing	_	_	_	_
45	signaling	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	G	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	CSF	_	PROPN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	TGF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	beta1	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	ability	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	normal	_	ADJ	_	Degree=Pos	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	fusion	_	NOUN	_	Number=Sing	_	_	_	_
27	proteins	_	NOUN	_	Number=Plur	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	repress	_	VERB	_	VerbForm=Inf	_	_	_	_
32	promoters	_	NOUN	_	Number=Plur	_	_	_	_
33	which	_	PRON	_	PronType=Rel	_	_	_	_
34	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
35	can	_	AUX	_	VerbForm=Fin	_	_	_	_
36	directly	_	ADV	_	_	_	_	_	_
37	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
38	by	_	SCONJ	_	_	_	_	_	_
39	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	site	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	mutations	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	MDS1	_	PROPN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	EVI1	_	NOUN	_	Number=Sing	_	_	_	_
9	either	_	CCONJ	_	_	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	truncation	_	NOUN	_	Number=Sing	_	_	_	_
13	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	repressor	_	NOUN	_	Number=Sing	_	_	_	_
18	EVI1	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	fusion	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	AML1	_	PROPN	_	Number=Sing	_	_	_	_
25	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	altered	_	VERB	_	Degree=Pos	_	_	_	_
29	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
30	response	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	growth	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
35	factors	_	NOUN	_	Number=Plur	_	_	_	_
36	that	_	PRON	_	PronType=Rel	_	_	_	_
37	could	_	AUX	_	VerbForm=Fin	_	_	_	_
38	result	_	VERB	_	VerbForm=Inf	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
41	transformation	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	different	_	ADJ	_	Degree=Pos	_	_	_	_
3	response	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	ectopically	_	ADV	_	_	_	_	_	_
8	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	normal	_	ADJ	_	Degree=Pos	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	fusion	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	G-CSF	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	TGF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	beta1	_	NOUN	_	Number=Sing	_	_	_	_
21	could	_	AUX	_	VerbForm=Fin	_	_	_	_
22	depend	_	VERB	_	VerbForm=Inf	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	different	_	ADJ	_	Degree=Pos	_	_	_	_
26	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
27	properties	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	divergent	_	ADJ	_	Degree=Pos	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
37	genes	_	NOUN	_	Number=Plur	_	_	_	_
38	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	two	_	NUM	_	NumType=Card	_	_	_	_
42	proteins	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003280	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	[	_	PUNCT	_	_	_	_	_	_
2	Glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
3	receptors	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	patients	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	bronchial	_	ADJ	_	Degree=Pos	_	_	_	_
12	asthma	_	NOUN	_	Number=Sing	_	_	_	_
13	]	_	PUNCT	_	_	_	_	_	_

1	Quantitation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
4	receptors	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	GCR	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	study	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	affinity	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	glucocorticosteroids	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	GCS	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	made	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
23	blood	_	NOUN	_	Number=Sing	_	_	_	_
24	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	bronchial	_	ADJ	_	Degree=Pos	_	_	_	_
27	asthma	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	BA	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	patients	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	consideration	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	GCR	_	NOUN	_	Number=Sing	_	_	_	_
36	treatment	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	serum	_	NOUN	_	Number=Sing	_	_	_	_
39	levels	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
42	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	stated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	GCR	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
8	controls	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	GCS	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
13	patients	_	NOUN	_	Number=Plur	_	_	_	_
14	outnumbered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	cortisol	_	ADJ	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	BA	_	NOUN	_	Number=Sing	_	_	_	_
21	patients	_	NOUN	_	Number=Plur	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	hormone	_	NOUN	_	Number=Sing	_	_	_	_
24	therapy	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Following	_	VERB	_	VerbForm=Ger	_	_	_	_
2	discontinuation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
5	drugs	_	NOUN	_	Number=Plur	_	_	_	_
6	GCR	_	NOUN	_	Number=Sing	_	_	_	_
7	count	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	cortisol	_	ADJ	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	BA	_	NOUN	_	Number=Sing	_	_	_	_
13	tends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	rise	_	VERB	_	VerbForm=Inf	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
2	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	no	_	DET	_	_	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	GCR	_	NOUN	_	Number=Sing	_	_	_	_
8	level	_	NOUN	_	Number=Sing	_	_	_	_
9	estimated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	3H	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	triamcinolone	_	NOUN	_	Number=Sing	_	_	_	_
14	acetonide	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003282	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	majority	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	patients	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
15	acute	_	ADJ	_	Degree=Pos	_	_	_	_
16	lymphoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
17	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
18	?	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	pediatric	_	ADJ	_	Degree=Pos	_	_	_	_
3	oncology	_	NOUN	_	Number=Sing	_	_	_	_
4	group	_	NOUN	_	Number=Sing	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	Almost	_	ADV	_	_	_	_	_	_
2	25	_	NUM	_	NumType=Card	_	_	_	_
3	%	_	SYM	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	patients	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
8	acute	_	ADJ	_	Degree=Pos	_	_	_	_
9	lymphoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
10	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	ALL	_	DET	_	_	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	tumor	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	TAL1	_	PROPN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	normal	_	ADJ	_	Degree=Pos	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	TAL1	_	ADJ	_	Degree=Pos	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	products	_	NOUN	_	Number=Plur	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	readily	_	ADV	_	_	_	_	_	_
17	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	harbor	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	rearranged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
26	allele	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Hence	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
6	proposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
12	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	development	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	T-ALL	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	TAL1	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	most	_	ADJ	_	Degree=Sup	_	_	_	_
17	patients	_	NOUN	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	T-ALL	_	ADJ	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	including	_	VERB	_	VerbForm=Ger	_	_	_	_
22	many	_	ADJ	_	Degree=Pos	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	display	_	VERB	_	VerbForm=Inf	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
29	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	alteration	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	polymorphic	_	ADJ	_	Degree=Pos	_	_	_	_
3	dinucleotide	_	NOUN	_	Number=Sing	_	_	_	_
4	repeat	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	transcribed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	sequences	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	allele	_	NOUN	_	Number=Sing	_	_	_	_
17	specificity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	primary	_	ADJ	_	Degree=Pos	_	_	_	_
23	T-ALL	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Monoallelic	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	all	_	DET	_	_	_	_	_	_
13	patients	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	8	_	NUM	_	NumType=Card	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	8	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	TAL1	_	NOUN	_	Degree=Pos	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	patients	_	NOUN	_	Number=Sing	_	_	_	_
7	without	_	ADP	_	_	_	_	_	_
8	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
9	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
10	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	either	_	CCONJ	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	monoallelic	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	7	_	NUM	_	NumType=Card	_	_	_	_
23	patients	_	NOUN	_	Number=Plur	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	biallelic	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	4	_	NUM	_	NumType=Card	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	7	_	NUM	_	NumType=Card	_	_	_	_
32	patients	_	NOUN	_	Number=Plur	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	fashion	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_

1	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	patients	_	NOUN	_	Number=Plur	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	result	_	VERB	_	VerbForm=Inf	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	subtle	_	ADJ	_	Degree=Pos	_	_	_	_
10	alterations	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	cis	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	sequences	_	NOUN	_	Number=Plur	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	single	_	ADJ	_	Degree=Pos	_	_	_	_
23	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
24	allele	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	changes	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	trans	_	NOUN	_	Number=Plur	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	acting	_	VERB	_	Number=Sing	_	_	_	_
32	factors	_	NOUN	_	Number=Plur	_	_	_	_
33	that	_	PRON	_	PronType=Rel	_	_	_	_
34	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
36	transcription	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	both	_	CCONJ	_	_	_	_	_	_
42	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
43	alleles	_	NOUN	_	Number=Plur	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003283	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	BCL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	6	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
7	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	presented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
8	lesion	_	NOUN	_	Number=Sing	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	DLCL	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	most	_	ADV	_	_	_	_	_	_
15	clinically	_	ADV	_	_	_	_	_	_
16	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
17	form	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	NHL	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	no	_	DET	_	_	_	_	_	_
3	proof	_	NOUN	_	Number=Sing	_	_	_	_
4	yet	_	ADV	_	_	_	_	_	_
5	exists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	lesions	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	DLCL	_	PROPN	_	Number=Sing	_	_	_	_
14	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	feature	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	BCL	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	6	_	NUM	_	NumType=Card	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	product	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	pattern	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	B	_	ADJ	_	Degree=Pos	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	clustering	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	lesions	_	NOUN	_	Number=Plur	_	_	_	_
40	disrupting	_	VERB	_	VerbForm=Ger	_	_	_	_
41	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
42	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
43	domain	_	NOUN	_	Number=Sing	_	_	_	_
44	strongly	_	ADV	_	_	_	_	_	_
45	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
46	that	_	SCONJ	_	_	_	_	_	_
47	deregulation	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	BCL	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	6	_	NUM	_	NumType=Card	_	_	_	_
52	expression	_	NOUN	_	Number=Sing	_	_	_	_
53	may	_	AUX	_	VerbForm=Fin	_	_	_	_
54	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
55	to	_	ADP	_	_	_	_	_	_
56	DLCL	_	PROPN	_	Number=Sing	_	_	_	_
57	development	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	more	_	ADV	_	_	_	_	_	_
3	precise	_	ADJ	_	Degree=Pos	_	_	_	_
4	definition	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	BCL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	6	_	NUM	_	NumType=Card	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	normal	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	neoplastic	_	ADJ	_	Degree=Pos	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	development	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	goal	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	ongoing	_	ADJ	_	Degree=Pos	_	_	_	_
25	study	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
28	mice	_	NOUN	_	Number=Plur	_	_	_	_
29	engineered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	either	_	ADV	_	_	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	express	_	VERB	_	VerbForm=Inf	_	_	_	_
33	BCL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	6	_	NUM	_	NumType=Card	_	_	_	_
36	under	_	ADP	_	_	_	_	_	_
37	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
38	promoters	_	NOUN	_	Number=Plur	_	_	_	_
39	or	_	CCONJ	_	_	_	_	_	_
40	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
41	BCL	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	6	_	NUM	_	NumType=Card	_	_	_	_
44	function	_	NOUN	_	Number=Sing	_	_	_	_
45	due	_	ADP	_	_	_	_	_	_
46	to	_	ADP	_	_	_	_	_	_
47	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	deletions	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	contributing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	understanding	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	DLCL	_	NOUN	_	Number=Sing	_	_	_	_
10	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	identification	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	BCL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	6	_	NUM	_	NumType=Card	_	_	_	_
18	lesions	_	NOUN	_	Number=Plur	_	_	_	_
19	may	_	AUX	_	VerbForm=Fin	_	_	_	_
20	have	_	VERB	_	VerbForm=Inf	_	_	_	_
21	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
22	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
23	implications	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	DLCL	_	PROPN	_	Number=Sing	_	_	_	_
2	represent	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	heterogeneous	_	ADJ	_	Degree=Pos	_	_	_	_
5	group	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	neoplasms	_	NOUN	_	Number=Plur	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	homogeneously	_	ADV	_	_	_	_	_	_
12	despite	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	fact	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	only	_	ADV	_	_	_	_	_	_
17	50	_	NUM	_	NumType=Card	_	_	_	_
18	%	_	SYM	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	patients	_	NOUN	_	Number=Plur	_	_	_	_
21	experience	_	VERB	_	Number=Sing	_	_	_	_
22	long	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	term	_	NOUN	_	Number=Sing	_	_	_	_
25	disease	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	free	_	ADJ	_	Degree=Pos	_	_	_	_
28	survival	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	Schneider	_	PROPN	_	Number=Sing	_	_	_	_
31	et	_	X	_	_	_	_	_	_
32	al	_	PROPN	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	1990	_	NUM	_	NumType=Card	_	_	_	_
2	)	_	PUNCT	_	_	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	fact	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	BCL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
8	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	biologically	_	ADV	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	clinically	_	ADV	_	_	_	_	_	_
12	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
13	subsets	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	DLCL	_	PROPN	_	Number=Sing	_	_	_	_
16	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
19	lesions	_	NOUN	_	Number=Plur	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	useful	_	ADJ	_	Degree=Pos	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	markers	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	selection	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	differential	_	NOUN	_	Degree=Pos	_	_	_	_
29	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
30	strategies	_	NOUN	_	Number=Plur	_	_	_	_
31	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	on	_	ADP	_	_	_	_	_	_
33	different	_	ADJ	_	Degree=Pos	_	_	_	_
34	risk	_	NOUN	_	Number=Sing	_	_	_	_
35	groups	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	BCL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	monitor	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	malignant	_	ADJ	_	Number=Sing	_	_	_	_
17	clone	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
20	PCR	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	techniques	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
3	remission	_	NOUN	_	Number=Sing	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
6	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	significant	_	ADJ	_	Degree=Pos	_	_	_	_
10	fraction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	DLCL	_	PROPN	_	Number=Sing	_	_	_	_
13	cases	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
16	markers	_	NOUN	_	Number=Plur	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	critical	_	ADJ	_	Degree=Pos	_	_	_	_
21	tools	_	NOUN	_	Number=Plur	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
24	monitoring	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
27	residual	_	ADJ	_	Degree=Pos	_	_	_	_
28	disease	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	early	_	ADJ	_	Degree=Pos	_	_	_	_
31	diagnosis	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	relapse	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	Gribben	_	PROPN	_	Number=Sing	_	_	_	_
36	et	_	X	_	_	_	_	_	_
37	al	_	PROPN	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	1993	_	NUM	_	NumType=Card	_	_	_	_
2	)	_	PUNCT	_	_	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003284	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Attenuation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	interferon	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
8	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	Leishmania	_	PROPN	_	Number=Sing	_	_	_	_
15	donovani	_	NOUN	_	Number=Sing	_	_	_	_
16	:	_	PUNCT	_	_	_	_	_	_
17	selective	_	ADJ	_	Degree=Pos	_	_	_	_
18	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	SCONJ	_	_	_	_	_	_
20	signaling	_	VERB	_	Number=Sing	_	_	_	_
21	through	_	ADP	_	_	_	_	_	_
22	Janus	_	PROPN	_	Number=Sing	_	_	_	_
23	kinases	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	gamma	_	NOUN	_	Number=Sing	_	_	_	_
10	interferon	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	impaired	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	Leishmania	_	PROPN	_	Number=Sing	_	_	_	_
19	donovani	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
24	involved	_	VERB	_	Degree=Pos	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	fully	_	ADV	_	_	_	_	_	_
28	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	changes	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	brought	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	about	_	ADV	_	_	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	gamma	_	NOUN	_	Number=Sing	_	_	_	_
10	interferon	_	NOUN	_	Number=Sing	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
15	transient	_	ADJ	_	Degree=Pos	_	_	_	_
16	increases	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	activities	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
24	kinases	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	including	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	Janus	_	PROPN	_	Number=Sing	_	_	_	_
29	kinases	_	NOUN	_	Number=Plur	_	_	_	_
30	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	Jak2	_	PROPN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
37	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	transcription	_	NOUN	_	Number=Sing	_	_	_	_
41	factor	_	NOUN	_	Number=Sing	_	_	_	_
42	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	accounting	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	impaired	_	VERB	_	Degree=Pos	_	_	_	_
9	responses	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	interferon	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	model	_	NOUN	_	Number=Sing	_	_	_	_
16	system	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	SCONJ	_	_	_	_	_	_
18	examining	_	VERB	_	VerbForm=Ger	_	_	_	_
19	overall	_	ADJ	_	Degree=Pos	_	_	_	_
20	changes	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
24	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	Jak2	_	PROPN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	developed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
39	12	_	NUM	_	NumType=Card	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	myristate	_	NOUN	_	Number=Sing	_	_	_	_
42	13	_	NUM	_	NumType=Card	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	acetate	_	ADJ	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
47	U	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	937	_	NUM	_	NumType=Card	_	_	_	_
50	cells	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	whole	_	ADJ	_	Degree=Pos	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	lysates	_	NOUN	_	Number=Plur	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	antiphosphotyrosine	_	NOUN	_	Number=Sing	_	_	_	_
9	immunoblotting	_	NOUN	_	Number=Sing	_	_	_	_
10	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	incubation	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	gamma	_	NOUN	_	Number=Sing	_	_	_	_
15	interferon	_	NOUN	_	Number=Sing	_	_	_	_
16	brought	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	about	_	ADP	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	increases	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	phosphotyrosine	_	NOUN	_	Number=Sing	_	_	_	_
22	labeling	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	several	_	ADJ	_	Degree=Pos	_	_	_	_
25	proteins	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	labeling	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	similar	_	ADJ	_	Degree=Pos	_	_	_	_
9	extents	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	control	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
19	infected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	L.	_	PROPN	_	Number=Sing	_	_	_	_
22	donovani	_	PROPN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	16	_	NUM	_	NumType=Card	_	_	_	_
25	h	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Jak2	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	immunoprecipitated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	control	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	interferon	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	tyrosine	_	ADJ	_	Degree=Pos	_	_	_	_
19	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	antiphosphotyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
27	immunoblotting	_	NOUN	_	Number=Sing	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	measured	_	VERB	_	VerbForm=Inf	_	_	_	_
32	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Tyrosine	_	PROPN	_	Number=Sing	_	_	_	_
2	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	Jak2	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	markedly	_	ADV	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	dose	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	manner	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	U	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	937	_	NUM	_	NumType=Card	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	incubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	gamma	_	NOUN	_	Number=Sing	_	_	_	_
28	interferon	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	L.	_	PROPN	_	Number=Sing	_	_	_	_
9	donovani	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
12	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	Jak2	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	markedly	_	ADV	_	_	_	_	_	_
22	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	upon	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	duration	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	exposure	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	L.	_	PROPN	_	Number=Sing	_	_	_	_
12	donovani	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	complete	_	ADJ	_	Degree=Pos	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	16	_	NUM	_	NumType=Card	_	_	_	_
20	h	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Results	_	NOUN	_	Number=Plur	_	_	_	_
2	similar	_	ADJ	_	Degree=Pos	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
5	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	U	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	937	_	NUM	_	NumType=Card	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
17	blood	_	NOUN	_	Number=Sing	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	infection	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	L.	_	PROPN	_	Number=Sing	_	_	_	_
12	donovani	_	PROPN	_	Number=Sing	_	_	_	_
13	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	impaired	_	VERB	_	Degree=Pos	_	_	_	_
16	gamma	_	NOUN	_	Number=Sing	_	_	_	_
17	interferon	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
21	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	selective	_	ADJ	_	Degree=Pos	_	_	_	_
24	effects	_	NOUN	_	Number=Plur	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	Jak	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
30	pathway	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Unresponsiveness	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	interferon	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	pathway	_	NOUN	_	Number=Sing	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
12	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	responses	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	leishmania	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003287	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Multiple	_	ADJ	_	Degree=Pos	_	_	_	_
2	proteins	_	NOUN	_	Number=Plur	_	_	_	_
3	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	repressor	_	NOUN	_	Number=Sing	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	3	_	NUM	_	NumType=Card	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	T	_	DET	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	directed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	positive	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	negative	_	ADJ	_	Degree=Pos	_	_	_	_
18	cis	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	DNA	_	NOUN	_	Number=Sing	_	_	_	_
22	elements	_	NOUN	_	Number=Plur	_	_	_	_
23	clustered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	within	_	ADP	_	_	_	_	_	_
25	300	_	NUM	_	NumType=Card	_	_	_	_
26	base	_	NOUN	_	Number=Sing	_	_	_	_
27	pairs	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
31	start	_	NOUN	_	Number=Sing	_	_	_	_
32	site	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	strong	_	ADJ	_	Degree=Pos	_	_	_	_
3	repressor	_	NOUN	_	Number=Sing	_	_	_	_
4	element	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	NIP	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	previously	_	ADV	_	_	_	_	_	_
16	mapped	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	segment	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	between	_	ADP	_	_	_	_	_	_
27	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	271	_	NUM	_	NumType=Card	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	-	_	SYM	_	_	_	_	_	_
32	250	_	NUM	_	NumType=Card	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	characterization	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	element	_	NOUN	_	Number=Sing	_	_	_	_
6	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	repression	_	NOUN	_	Number=Sing	_	_	_	_
12	when	_	ADV	_	PronType=Int	_	_	_	_
13	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	cis	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	carried	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	out	_	ADP	_	_	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	repressor	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	varying	_	ADJ	_	Degree=Pos	_	_	_	_
3	conditions	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	three	_	NUM	_	NumType=Card	_	_	_	_
6	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
7	complexes	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
12	specifically	_	ADV	_	_	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	NIP	_	PROPN	_	Number=Sing	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	although	_	SCONJ	_	_	_	_	_	_
19	only	_	ADV	_	_	_	_	_	_
20	one	_	NUM	_	NumType=Card	_	_	_	_
21	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	repressor	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Complex	_	NOUN	_	Number=Sing	_	_	_	_
2	1	_	NUM	_	NumType=Card	_	_	_	_
3	results	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
9	polypeptide	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	3	_	NUM	_	NumType=Card	_	_	_	_
14	'	_	PUNCT	_	_	_	_	_	_
15	portion	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
18	sequence	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	repression	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Complex	_	ADJ	_	Degree=Pos	_	_	_	_
2	2	_	NUM	_	NumType=Card	_	_	_	_
3	corresponds	_	NOUN	_	Number=Plur	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
11	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	E	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	box	_	NOUN	_	Number=Sing	_	_	_	_
19	motif	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	5	_	NUM	_	NumType=Card	_	_	_	_
23	'	_	PUNCT	_	_	_	_	_	_
24	portion	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	NIP	_	PROPN	_	Number=Sing	_	_	_	_
28	region	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
3	specificity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	complex	_	ADJ	_	Degree=Pos	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	overlaps	_	NOUN	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
12	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	clearly	_	ADV	_	_	_	_	_	_
17	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	which	_	PRON	_	PronType=Int	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	latter	_	ADJ	_	Degree=Pos	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	complexes	_	NOUN	_	Number=Plur	_	_	_	_
9	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	NIP	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	incorporated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	small	_	ADJ	_	Degree=Pos	_	_	_	_
16	alterations	_	NOUN	_	Number=Plur	_	_	_	_
17	into	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	NIP	_	NOUN	_	Number=Sing	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	3	_	NUM	_	NumType=Card	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	reporter	_	NOUN	_	Number=Sing	_	_	_	_
30	construct	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	effects	_	NOUN	_	Number=Plur	_	_	_	_
35	on	_	ADP	_	_	_	_	_	_
36	NIP	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	repression	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	specificity	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	repression	_	NOUN	_	Number=Sing	_	_	_	_
5	matches	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	DNA	_	PROPN	_	Number=Sing	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	specificity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	complex	_	NOUN	_	Number=Sing	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	;	_	PUNCT	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	repressor	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	complex	_	NOUN	_	Degree=Pos	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	binding	_	NOUN	_	Number=Plur	_	_	_	_
21	require	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	consensus	_	NOUN	_	Number=Sing	_	_	_	_
24	sequence	_	NOUN	_	Number=Sing	_	_	_	_
25	CTCACNTNC	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003292	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	12	_	NUM	_	NumType=Card	_	_	_	_
3	induces	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
5	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	STAT4	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	12	_	NUM	_	NumType=Card	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	12	_	NUM	_	NumType=Card	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	immunoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
13	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	member	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	hematopoietin	_	NOUN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	recently	_	ADV	_	_	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	natural	_	ADJ	_	Degree=Pos	_	_	_	_
12	killer	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	12	_	NUM	_	NumType=Card	_	_	_	_
18	induces	_	NOUN	_	Number=Plur	_	_	_	_
19	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
20	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	Janus	_	PROPN	_	Number=Sing	_	_	_	_
24	family	_	NOUN	_	Number=Sing	_	_	_	_
25	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
26	kinase	_	NOUN	_	Number=Sing	_	_	_	_
27	JAK2	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	Tyk2	_	PROPN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	implicating	_	VERB	_	VerbForm=Ger	_	_	_	_
32	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
33	kinases	_	NOUN	_	Number=Plur	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
37	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
38	response	_	NOUN	_	Number=Sing	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	12	_	NUM	_	NumType=Card	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	STATs	_	NOUN	_	Number=Plur	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	signal	_	NOUN	_	Number=Sing	_	_	_	_
10	transducers	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	activators	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
18	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	tyrosine	_	ADJ	_	Degree=Pos	_	_	_	_
22	phosphorylated	_	VERB	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	response	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	number	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
32	that	_	PRON	_	PronType=Rel	_	_	_	_
33	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	hematopoietin	_	NOUN	_	Degree=Pos	_	_	_	_
35	receptors	_	NOUN	_	Number=Plur	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	JAK	_	PROPN	_	Number=Sing	_	_	_	_
39	kinases	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	12	_	NUM	_	NumType=Card	_	_	_	_
10	induces	_	NOUN	_	Number=Plur	_	_	_	_
11	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
12	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	recently	_	ADV	_	_	_	_	_	_
16	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	STAT	_	PROPN	_	Number=Sing	_	_	_	_
18	family	_	NOUN	_	Number=Sing	_	_	_	_
19	member	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	STAT4	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	STAT4	_	PROPN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	12	_	NUM	_	NumType=Card	_	_	_	_
9	stimulates	_	VERB	_	Number=Plur	_	_	_	_
10	formation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	complex	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	DNA	_	PROPN	_	Number=Sing	_	_	_	_
21	sequence	_	NOUN	_	Number=Sing	_	_	_	_
22	previously	_	ADV	_	_	_	_	_	_
23	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
26	STAT	_	PROPN	_	Number=Sing	_	_	_	_
27	proteins	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	complex	_	NOUN	_	Number=Sing	_	_	_	_
32	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	STAT4	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	recent	_	ADJ	_	Degree=Pos	_	_	_	_
7	demonstration	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	JAK	_	PROPN	_	Number=Sing	_	_	_	_
10	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	12	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	identify	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
19	signal	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	transduction	_	NOUN	_	Number=Sing	_	_	_	_
22	pathway	_	NOUN	_	Number=Sing	_	_	_	_
23	likely	_	ADV	_	Degree=Pos	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	12	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003295	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Heterogeneous	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	Barr	_	PROPN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	latent	_	ADJ	_	Degree=Pos	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	endemic	_	ADJ	_	Number=Sing	_	_	_	_
12	Burkitt	_	PROPN	_	Number=Sing	_	_	_	_
13	's	_	PART	_	_	_	_	_	_
14	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Barr	_	PROPN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EBV	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	sustain	_	VERB	_	VerbForm=Inf	_	_	_	_
13	three	_	NUM	_	NumType=Card	_	_	_	_
14	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
15	forms	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	latency	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	lymphoblastoid	_	ADJ	_	Degree=Pos	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	six	_	NUM	_	NumType=Card	_	_	_	_
7	EBV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	antigens	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	EBNA1	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	3A	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	3B	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	3	_	NUM	_	NumType=Card	_	_	_	_
22	C	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	LP	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	three	_	NUM	_	NumType=Card	_	_	_	_
29	latent	_	ADJ	_	Degree=Pos	_	_	_	_
30	membrane	_	NOUN	_	Number=Sing	_	_	_	_
31	proteins	_	NOUN	_	Number=Plur	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	2A	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	2B	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	two	_	NUM	_	NumType=Card	_	_	_	_
42	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
43	RNAs	_	NOUN	_	Number=Plur	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	EBERs	_	PROPN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
48	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	form	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	latency	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	latency	_	NOUN	_	Number=Sing	_	_	_	_
8	III	_	NUM	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	encountered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	some	_	DET	_	_	_	_	_	_
15	posttransplant	_	ADJ	_	Degree=Pos	_	_	_	_
16	lymphoproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
17	disorders	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	EBV	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	positive	_	ADJ	_	Degree=Pos	_	_	_	_
5	cases	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Hodgkin	_	PROPN	_	Number=Sing	_	_	_	_
8	's	_	PART	_	_	_	_	_	_
9	disease	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	EBERs	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	EBNA1	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	LMPs	_	NOUN	_	Number=Plur	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	latency	_	NOUN	_	Number=Sing	_	_	_	_
23	II	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	whereas	_	SCONJ	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	Burkitt	_	PROPN	_	Number=Sing	_	_	_	_
29	's	_	PART	_	_	_	_	_	_
30	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	BL	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	only	_	ADV	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	EBERs	_	PROPN	_	Number=Plur	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	EBNA1	_	PROPN	_	Number=Sing	_	_	_	_
39	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
41	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	latency	_	NOUN	_	Number=Sing	_	_	_	_
44	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	EBV	_	PROPN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	17	_	NUM	_	NumType=Card	_	_	_	_
11	cases	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	EBV	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	positive	_	ADJ	_	Degree=Pos	_	_	_	_
16	endemic	_	ADJ	_	Degree=Pos	_	_	_	_
17	BL	_	PROPN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	immunohistology	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	variable	_	ADJ	_	Degree=Pos	_	_	_	_
8	proportions	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	tumor	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	two	_	NUM	_	NumType=Card	_	_	_	_
14	cases	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	EBNA2	_	PROPN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	some	_	DET	_	_	_	_	_	_
21	tumor	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	three	_	NUM	_	NumType=Card	_	_	_	_
25	other	_	ADJ	_	Degree=Pos	_	_	_	_
26	cases	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Also	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	BZLF1	_	PROPN	_	Number=Sing	_	_	_	_
5	trans	_	NOUN	_	Number=Plur	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	activator	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	few	_	ADJ	_	Degree=Pos	_	_	_	_
14	tumor	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	6	_	NUM	_	NumType=Card	_	_	_	_
18	cases	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	entry	_	NOUN	_	Number=Sing	_	_	_	_
22	into	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	cycle	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
3	drift	_	NOUN	_	Number=Sing	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	latency	_	NOUN	_	Number=Sing	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	latency	_	NOUN	_	Number=Sing	_	_	_	_
9	III	_	PROPN	_	Number=Sing	_	_	_	_
10	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	previously	_	ADV	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	some	_	DET	_	_	_	_	_	_
16	BL	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lines	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	similar	_	ADJ	_	Degree=Pos	_	_	_	_
7	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	BL	_	PROPN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vivo	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	indicate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	operational	_	ADJ	_	Degree=Pos	_	_	_	_
19	definition	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	EBV	_	NOUN	_	Number=Sing	_	_	_	_
22	latencies	_	NOUN	_	Number=Plur	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	easily	_	ADV	_	_	_	_	_	_
26	applied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	tumors	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003298	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	acute	_	ADJ	_	Degree=Pos	_	_	_	_
9	megakaryoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
10	leukaemia	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	transient	_	ADJ	_	Degree=Pos	_	_	_	_
13	myeloproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
14	disorder	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	Down	_	PROPN	_	Number=Sing	_	_	_	_
17	's	_	PART	_	_	_	_	_	_
18	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Acute	_	ADJ	_	Degree=Pos	_	_	_	_
2	megakaryoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
3	leukaemia	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	M7	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	transient	_	ADJ	_	Degree=Pos	_	_	_	_
9	myeloproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
10	disorder	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	Down	_	PROPN	_	Number=Sing	_	_	_	_
13	's	_	PART	_	_	_	_	_	_
14	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	TMD	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
22	growth	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
25	blast	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
30	markers	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	clarify	_	VERB	_	VerbForm=Inf	_	_	_	_
3	properties	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	blast	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	M7	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	TMD	_	NOUN	_	Number=Sing	_	_	_	_
12	cases	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
17	markers	_	NOUN	_	Number=Plur	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	blasts	_	NOUN	_	Number=Plur	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	six	_	NUM	_	NumType=Card	_	_	_	_
23	cases	_	NOUN	_	Number=Plur	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	M7	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	seven	_	NUM	_	NumType=Card	_	_	_	_
28	cases	_	NOUN	_	Number=Plur	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	TMD	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	study	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Erythroid	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
5	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
6	gamma	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	globin	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
11	delta	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	aminolevulinate	_	ADJ	_	Degree=Pos	_	_	_	_
14	synthase	_	NOUN	_	Number=Sing	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	blasts	_	NOUN	_	Number=Plur	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	most	_	ADJ	_	Degree=Sup	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	cases	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	majorities	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	blasts	_	NOUN	_	Number=Plur	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	M7	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	TMD	_	NOUN	_	Number=Sing	_	_	_	_
38	cases	_	NOUN	_	Number=Plur	_	_	_	_
39	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
43	phenotypes	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	mRNAs	_	PROPN	_	Number=Plur	_	_	_	_
6	encoding	_	VERB	_	Number=Sing	_	_	_	_
7	GATA	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	GATA	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	all	_	DET	_	_	_	_	_	_
18	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
19	cases	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	M7	_	PROPN	_	Number=Sing	_	_	_	_
6	blasts	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	TMD	_	NOUN	_	Number=Sing	_	_	_	_
9	blasts	_	NOUN	_	Number=Plur	_	_	_	_
10	correspond	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	bipotential	_	ADJ	_	Degree=Pos	_	_	_	_
17	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003299	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Growth	_	NOUN	_	Number=Sing	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	changes	_	NOUN	_	Number=Plur	_	_	_	_
6	during	_	ADP	_	_	_	_	_	_
7	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	prostatic	_	ADJ	_	Number=Sing	_	_	_	_
11	cancer	_	NOUN	_	Number=Sing	_	_	_	_
12	LNCaP	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	as	_	SCONJ	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	conditioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	medium	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	prostatic	_	ADJ	_	Degree=Pos	_	_	_	_
3	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	androgen	_	NOUN	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	LNCaP	_	NOUN	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	line	_	NOUN	_	Number=Sing	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	response	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	conditioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	medium	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	CM	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	PHA	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Addition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CM	_	NOUN	_	Number=Sing	_	_	_	_
4	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
7	than	_	ADP	_	_	_	_	_	_
8	70	_	NUM	_	NumType=Card	_	_	_	_
9	%	_	SYM	_	Number=Sing	_	_	_	_
10	reduction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	counting	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	cycle	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	G1	_	PROPN	_	Number=Sing	_	_	_	_
5	phase	_	NOUN	_	Number=Sing	_	_	_	_
6	arrest	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	clonogenicity	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	growth	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	dose	_	ADV	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	not	_	ADV	_	_	_	_	_	_
12	due	_	ADP	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	lysis	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	androgen	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	androgen	_	VERB	_	Degree=Pos	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	approximately	_	ADV	_	_	_	_	_	_
13	50	_	NUM	_	NumType=Card	_	_	_	_
14	%	_	SYM	_	Number=Sing	_	_	_	_
15	reduction	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	underlining	_	VERB	_	VerbForm=Ger	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
20	reduction	_	NOUN	_	Number=Sing	_	_	_	_
21	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	prostate	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	antigen	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	PSA	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	downregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	approximately	_	ADV	_	_	_	_	_	_
13	75	_	NUM	_	NumType=Card	_	_	_	_
14	%	_	SYM	_	Number=Sing	_	_	_	_
15	during	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	process	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	morphology	_	NOUN	_	Number=Sing	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
5	processes	_	NOUN	_	Number=Plur	_	_	_	_
6	extending	_	VERB	_	VerbForm=Ger	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	other	_	ADJ	_	Degree=Pos	_	_	_	_
11	neuroendocrine	_	NOUN	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	several	_	ADJ	_	Degree=Pos	_	_	_	_
5	cytoskeleton	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	as	_	SCONJ	_	_	_	_	_	_
11	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	immunostaining	_	ADJ	_	VerbForm=Ger	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	slides	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	ELISA	_	PROPN	_	Number=Sing	_	_	_	_
19	procedures	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
2	included	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	vimentin	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	correlating	_	ADJ	_	VerbForm=Ger	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	shape	_	NOUN	_	Number=Sing	_	_	_	_
9	changes	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	cytokeratins	_	NOUN	_	Number=Plur	_	_	_	_
12	8	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	18	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	types	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	prostate	_	ADJ	_	Number=Sing	_	_	_	_
23	epithelia	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	neuron	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	specific	_	ADJ	_	Degree=Pos	_	_	_	_
29	enolase	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	serotonin	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	neuroendocrine	_	NOUN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	From	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
4	changes	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	infer	_	VERB	_	VerbForm=Inf	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	along	_	ADP	_	_	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
20	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	important	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	SCONJ	_	_	_	_	_	_
10	providing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	modulating	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	growth	_	NOUN	_	Number=Sing	_	_	_	_
3	modulator	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	semipurified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	estimated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
11	weight	_	NOUN	_	Number=Sing	_	_	_	_
12	13,000	_	NUM	_	NumType=Card	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	24,000	_	NUM	_	NumType=Card	_	_	_	_
15	Da	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	determined	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	TGF	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	some	_	DET	_	_	_	_	_	_
15	commonly	_	ADV	_	_	_	_	_	_
16	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	lymphokines	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	interaction	_	NOUN	_	Number=Sing	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	prostatic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	growth	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	development	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003300	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
3	forms	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	active	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	CREB	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
6	forms	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	CREB	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	apparently	_	ADV	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	products	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
25	splicing	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	CREB	_	NOUN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	transcript	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	14	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	amino	_	NOUN	_	Number=Sing	_	_	_	_
10	acid	_	ADJ	_	Number=Sing	_	_	_	_
11	serine	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	rich	_	ADJ	_	Degree=Pos	_	_	_	_
14	insertion	_	NOUN	_	Number=Sing	_	_	_	_
15	present	_	VERB	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	one	_	NUM	_	NumType=Card	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	CREB	_	NOUN	_	Number=Sing	_	_	_	_
21	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	both	_	DET	_	_	_	_	_	_
5	CREB	_	NOUN	_	Number=Sing	_	_	_	_
6	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	many	_	ADJ	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	types	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
15	species	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	encode	_	NOUN	_	Number=Sing	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	specifically	_	ADV	_	_	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	element	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vitro	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	expected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	proteins	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	class	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	CREB	_	NOUN	_	Number=Sing	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	dimers	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	proteins	_	NOUN	_	Number=Plur	_	_	_	_
3	impart	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	binding	_	VERB	_	Number=Sing	_	_	_	_
15	domain	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	showing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	that	_	DET	_	_	_	_	_	_
19	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
20	directly	_	ADV	_	_	_	_	_	_
21	modulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
24	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	CREB	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	presence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
5	CREB	_	NOUN	_	Number=Sing	_	_	_	_
6	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	identical	_	ADJ	_	Degree=Pos	_	_	_	_
9	DNA	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	specificities	_	NOUN	_	Number=Plur	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	differences	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	presumed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	domain	_	NOUN	_	Number=Sing	_	_	_	_
20	raises	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	possibility	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	CREB	_	PROPN	_	Number=Sing	_	_	_	_
25	proteins	_	NOUN	_	Number=Plur	_	_	_	_
26	may	_	AUX	_	VerbForm=Fin	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	able	_	ADJ	_	Degree=Pos	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	integrate	_	VERB	_	VerbForm=Inf	_	_	_	_
31	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
32	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
33	signals	_	NOUN	_	Number=Plur	_	_	_	_
34	at	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	level	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003302	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	as	_	ADP	_	_	_	_	_	_
4	targets	_	NOUN	_	Number=Plur	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
7	signalling	_	NOUN	_	Number=Sing	_	_	_	_
8	during	_	ADP	_	_	_	_	_	_
9	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	requirement	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
9	events	_	NOUN	_	Number=Plur	_	_	_	_
10	during	_	ADP	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	cycle	_	NOUN	_	Number=Sing	_	_	_	_
13	entry	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	hypothesised	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
22	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
23	species	_	NOUN	_	Number=Plur	_	_	_	_
24	may	_	AUX	_	VerbForm=Fin	_	_	_	_
25	act	_	VERB	_	VerbForm=Inf	_	_	_	_
26	as	_	ADP	_	_	_	_	_	_
27	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
28	signalling	_	VERB	_	Number=Sing	_	_	_	_
29	agents	_	NOUN	_	Number=Plur	_	_	_	_
30	during	_	ADP	_	_	_	_	_	_
31	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	current	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	cysteamine	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	aminothiol	_	ADJ	_	Number=Sing	_	_	_	_
10	compound	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	further	_	ADV	_	_	_	_	_	_
20	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
25	signalling	_	NOUN	_	Number=Sing	_	_	_	_
26	during	_	ADP	_	_	_	_	_	_
27	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	normal	_	ADJ	_	Degree=Pos	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	cysteamine	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	vitro	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
16	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	dose	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	manner	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	essentially	_	ADV	_	_	_	_	_	_
26	complete	_	ADJ	_	Degree=Pos	_	_	_	_
27	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
28	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
29	at	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	dose	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	400	_	NUM	_	NumType=Card	_	_	_	_
34	microM	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	limited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	h	_	NOUN	_	Number=Sing	_	_	_	_
11	after	_	ADP	_	_	_	_	_	_
12	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	localizing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	time	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	frame	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	action	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	cysteamine	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	within	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	commitment	_	NOUN	_	Number=Sing	_	_	_	_
28	period	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	interest	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	establish	_	VERB	_	VerbForm=Inf	_	_	_	_
8	which	_	PRON	_	PronType=Int	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	if	_	SCONJ	_	_	_	_	_	_
11	any	_	DET	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	commitment	_	NOUN	_	Number=Sing	_	_	_	_
14	events	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
19	signalling	_	NOUN	_	Number=Sing	_	_	_	_
20	during	_	ADP	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	cycle	_	NOUN	_	Number=Sing	_	_	_	_
23	entry	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Taking	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	candidate	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	effect	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	cysteamine	_	ADJ	_	Number=Sing	_	_	_	_
17	treatment	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	early	_	ADJ	_	Degree=Pos	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	during	_	ADP	_	_	_	_	_	_
23	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	factors	_	NOUN	_	Number=Plur	_	_	_	_
33	AP	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kappa	_	PROPN	_	Number=Sing	_	_	_	_
40	B	_	PROPN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	NF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	AT	_	ADP	_	Number=Sing	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	Oct1	_	PROPN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
49	functions	_	NOUN	_	Number=Plur	_	_	_	_
50	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
51	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	for	_	ADP	_	_	_	_	_	_
53	expression	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	IL	_	PROPN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	2	_	NUM	_	NumType=Card	_	_	_	_
59	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Cysteamine	_	ADJ	_	Number=Sing	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	both	_	DET	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	secretion	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	into	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	culture	_	NOUN	_	Number=Sing	_	_	_	_
21	medium	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	cysteamine	_	NOUN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	at	_	ADV	_	_	_	_	_	_
10	least	_	ADV	_	Degree=Sup	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	part	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	effect	_	NOUN	_	Number=Sing	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	function	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	as	_	SCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	DNA	_	PROPN	_	Number=Sing	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	activities	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	AP	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	extracted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	from	_	ADP	_	_	_	_	_	_
37	mitogen	_	ADJ	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
42	significantly	_	ADV	_	_	_	_	_	_
43	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	by	_	ADP	_	_	_	_	_	_
45	cysteamine	_	ADJ	_	Number=Sing	_	_	_	_
46	treatment	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Oct1	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	AT	_	ADP	_	_	_	_	_	_
8	DNA	_	PROPN	_	Number=Sing	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	cysteamine	_	ADJ	_	Degree=Pos	_	_	_	_
16	treatment	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
21	signalling	_	NOUN	_	Number=Sing	_	_	_	_
22	processes	_	NOUN	_	Number=Plur	_	_	_	_
23	operate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	selective	_	ADJ	_	Degree=Pos	_	_	_	_
27	manner	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	identification	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	such	_	ADJ	_	Degree=Pos	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
14	targets	_	NOUN	_	Number=Plur	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
17	signalling	_	NOUN	_	Number=Sing	_	_	_	_
18	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	further	_	ADJ	_	Degree=Pos	_	_	_	_
20	evidence	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	implicate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
24	signalling	_	NOUN	_	Number=Sing	_	_	_	_
25	as	_	SCONJ	_	_	_	_	_	_
26	being	_	AUX	_	VerbForm=Ger	_	_	_	_
27	intimately	_	ADV	_	_	_	_	_	_
28	involved	_	ADJ	_	Degree=Pos	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	G0	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	G1	_	PROPN	_	Number=Sing	_	_	_	_
34	phase	_	NOUN	_	Number=Sing	_	_	_	_
35	transition	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	T	_	PROPN	_	Number=Sing	_	_	_	_
38	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003303	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Constitutively	_	ADV	_	_	_	_	_	_
2	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	Jak	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	STAT	_	PROPN	_	Number=Sing	_	_	_	_
6	pathway	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lymphotropic	_	ADJ	_	Degree=Pos	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	etiological	_	ADJ	_	Degree=Pos	_	_	_	_
15	agent	_	NOUN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	adult	_	ADJ	_	Number=Sing	_	_	_	_
18	T	_	PROPN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	tropical	_	ADJ	_	Degree=Pos	_	_	_	_
23	spastic	_	ADJ	_	Degree=Pos	_	_	_	_
24	paraparesis	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	also	_	ADV	_	_	_	_	_	_
27	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	I-associated	_	ADJ	_	Degree=Pos	_	_	_	_
31	myelopathy	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	I-infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
5	blood	_	NOUN	_	Number=Sing	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	exhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	initial	_	ADJ	_	Degree=Pos	_	_	_	_
11	phase	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	growth	_	NOUN	_	Number=Sing	_	_	_	_
24	;	_	PUNCT	_	_	_	_	_	_
25	over	_	ADP	_	_	_	_	_	_
26	time	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
31	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	become	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	independent	_	ADJ	_	Degree=Pos	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	Jak	_	PROPN	_	Number=Sing	_	_	_	_
4	kinases	_	NOUN	_	Number=Plur	_	_	_	_
5	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	transducer	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	activator	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	normal	_	ADJ	_	Degree=Pos	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	response	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
34	signaling	_	NOUN	_	Number=Sing	_	_	_	_
35	pathway	_	NOUN	_	Number=Sing	_	_	_	_
36	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
37	constitutively	_	ADV	_	_	_	_	_	_
38	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	I-transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	I-infected	_	VERB	_	Degree=Pos	_	_	_	_
5	cord	_	NOUN	_	Number=Sing	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transition	_	NOUN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	independent	_	ADJ	_	Degree=Pos	_	_	_	_
23	growth	_	NOUN	_	Number=Sing	_	_	_	_
24	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	acquisition	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	constitutively	_	ADV	_	_	_	_	_	_
31	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	Jak	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	STAT	_	PROPN	_	Number=Sing	_	_	_	_
35	pathway	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	which	_	PRON	_	PronType=Rel	_	_	_	_
38	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	that	_	SCONJ	_	_	_	_	_	_
40	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
41	pathway	_	NOUN	_	Number=Sing	_	_	_	_
42	participates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	I-mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
47	T	_	NOUN	_	Number=Sing	_	_	_	_
48	cell	_	NOUN	_	Number=Sing	_	_	_	_
49	transformation	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003306	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	CD43	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	leukosialin-mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
7	pathway	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	SCONJ	_	_	_	_	_	_
9	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	T-lymphoblastoid	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
3	antibody	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	mAb	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	J393	_	NUM	_	Number=Sing	_	_	_	_
8	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
12	T-cells	_	PROPN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	NH2	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	terminal	_	ADJ	_	Number=Sing	_	_	_	_
4	amino	_	NOUN	_	Number=Sing	_	_	_	_
5	acid	_	NOUN	_	Number=Sing	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	analysis	_	NOUN	_	Number=Sing	_	_	_	_
8	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	140	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kDa	_	NOUN	_	Number=Sing	_	_	_	_
13	surface	_	NOUN	_	Number=Sing	_	_	_	_
14	antigen	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	mAb	_	PROPN	_	Number=Sing	_	_	_	_
17	J393	_	NUM	_	Number=Sing	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	CD43	_	PROPN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	leukosialin	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	major	_	ADJ	_	Degree=Pos	_	_	_	_
25	sialoglycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	co	_	PROPN	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	discrete	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	surface	_	NOUN	_	Number=Sing	_	_	_	_
12	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	CD43	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	recognized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	mAb	_	PROPN	_	Number=Sing	_	_	_	_
19	J393	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	mAb	_	PROPN	_	Number=Sing	_	_	_	_
22	G10	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	respectively	_	ADV	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	only	_	ADV	_	_	_	_	_	_
29	J393	_	NUM	_	NumType=Card	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	CD43	_	PROPN	_	Number=Sing	_	_	_	_
32	signaled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	J393/CD43	_	NOUN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	hyposialylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	predominantly	_	ADV	_	_	_	_	_	_
10	O-linked	_	ADJ	_	Degree=Pos	_	_	_	_
11	monosaccharide	_	ADJ	_	Degree=Pos	_	_	_	_
12	glycans	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	whereas	_	SCONJ	_	_	_	_	_	_
15	G10-2	_	PROPN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	CD43	_	PROPN	_	Number=Sing	_	_	_	_
18	bore	_	NOUN	_	Number=Sing	_	_	_	_
19	complex	_	NOUN	_	Number=Sing	_	_	_	_
20	sialylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	tetra	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	hexasaccharide	_	ADJ	_	Degree=Pos	_	_	_	_
25	chains	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	soluble	_	ADJ	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	bivalent	_	ADJ	_	Degree=Pos	_	_	_	_
6	mAb	_	NOUN	_	Number=Sing	_	_	_	_
7	J393	_	PROPN	_	Number=Sing	_	_	_	_
8	killed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	25	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	SYM	_	_	_	_	_	_
11	50	_	NUM	_	NumType=Card	_	_	_	_
12	%	_	SYM	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	population	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	while	_	SCONJ	_	_	_	_	_	_
19	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
20	engagement	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	either	_	CCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	CD3	_	PROPN	_	Number=Sing	_	_	_	_
25	.TcR	_	NOUN	_	Number=Sing	_	_	_	_
26	complex	_	NOUN	_	Number=Sing	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	integrins	_	PROPN	_	Number=Plur	_	_	_	_
30	CD18	_	PROPN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	CD29	_	PROPN	_	Number=Sing	_	_	_	_
33	significantly	_	ADV	_	_	_	_	_	_
34	potentiated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
36	effect	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	mAb	_	PROPN	_	Number=Sing	_	_	_	_
7	J393	_	PROPN	_	Number=Sing	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
10	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	substrates	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	underwent	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	hyperphosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
18	upon	_	ADP	_	_	_	_	_	_
19	antigen	_	NOUN	_	Number=Sing	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Tyrosine	_	PROPN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	herbimycin	_	NOUN	_	Number=Sing	_	_	_	_
6	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	diminished	_	ADJ	_	Degree=Pos	_	_	_	_
8	J393	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	CD43	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
13	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	whereas	_	SCONJ	_	_	_	_	_	_
16	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	phosphotyrosine	_	NOUN	_	Number=Sing	_	_	_	_
19	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	bis	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	maltolato	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	oxovanadium	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	IV	_	NOUN	_	Number=Sing	_	_	_	_
29	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	death	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Signal	_	ADJ	_	Number=Sing	_	_	_	_
2	transduction	_	NOUN	_	Number=Sing	_	_	_	_
3	through	_	ADP	_	_	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	altered	_	VERB	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	J393	_	NUM	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	CD43	_	PROPN	_	Number=Sing	_	_	_	_
18	ligation	_	NOUN	_	Number=Sing	_	_	_	_
19	prompted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	decreases	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	localization	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
28	regulatory	_	ADJ	_	Number=Sing	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	proteins	_	NOUN	_	Number=Plur	_	_	_	_
35	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	interferon	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	inducible	_	ADJ	_	Number=Sing	_	_	_	_
40	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
41	element	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	ADP	_	_	_	_	_	_
2	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
3	blood	_	NOUN	_	Number=Sing	_	_	_	_
4	T-lymphocytes	_	PROPN	_	Number=Sing	_	_	_	_
5	express	_	VERB	_	Degree=Pos	_	_	_	_
6	cryptic	_	ADJ	_	Degree=Pos	_	_	_	_
7	epitopes	_	NOUN	_	Number=Plur	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	mAb	_	PROPN	_	Number=Sing	_	_	_	_
10	J393	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	findings	_	NOUN	_	Number=Plur	_	_	_	_
14	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	existence	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	tightly	_	ADV	_	_	_	_	_	_
20	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	CD43	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
24	pathway	_	NOUN	_	Number=Sing	_	_	_	_
25	for	_	SCONJ	_	_	_	_	_	_
26	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
27	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
31	lineages	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003307	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	1,25	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_

1	D3	_	PROPN	_	Number=Sing	_	_	_	_
2	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
7	acid	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
10	acute	_	ADJ	_	Degree=Pos	_	_	_	_
11	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	line	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	UF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	p21(WAF1	_	NOUN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	CIP1	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	p27(KIP1	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Retinoic	_	PROPN	_	Number=Sing	_	_	_	_
2	acid	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	RA	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	resistance	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	serious	_	ADJ	_	Degree=Pos	_	_	_	_
10	problem	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	patients	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	acute	_	ADJ	_	Degree=Pos	_	_	_	_
15	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	APL	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	who	_	PRON	_	PronType=Rel	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	receiving	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
23	all	_	DET	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	trans	_	NOUN	_	Number=Sing	_	_	_	_
26	RA	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	strategies	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	overcome	_	VERB	_	VerbForm=Inf	_	_	_	_
9	RA	_	PROPN	_	Number=Sing	_	_	_	_
10	resistance	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	APL	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	still	_	ADV	_	_	_	_	_	_
16	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	biologic	_	ADJ	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	RA	_	PROPN	_	Number=Sing	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
11	families	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_

1	RA	_	PROPN	_	Number=Sing	_	_	_	_
2	receptors	_	NOUN	_	Number=Plur	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	RARs	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	retinoid	_	VERB	_	Number=Sing	_	_	_	_
8	X	_	SYM	_	_	_	_	_	_
9	receptors	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	RXRs	_	NOUN	_	Number=Plur	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	RXRs	_	NOUN	_	_	_	_	_	_
2	heterodimerize	_	VERB	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	25	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
9	D3	_	NOUN	_	Number=Sing	_	_	_	_
10	[	_	PUNCT	_	_	_	_	_	_
11	1,25	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	OH	_	NOUN	_	_	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	2D3	_	NUM	_	Number=Sing	_	_	_	_
16	]	_	PUNCT	_	_	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	VDR	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	enabling	_	VERB	_	VerbForm=Ger	_	_	_	_
23	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
25	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	cdk	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
10	p21	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	WAF1	_	PROPN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	CIP1	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
19	D3	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
22	element	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	VDRE	_	X	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	1,25	_	NUM	_	NumType=Card	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	OH	_	INTJ	_	_	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	2D3	_	NUM	_	Number=Sing	_	_	_	_
36	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	p21	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	WAF1	_	NOUN	_	Number=Sing	_	_	_	_
43	/	_	PUNCT	_	_	_	_	_	_
44	CIP1	_	NOUN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
48	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
52	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
53	cell	_	NOUN	_	Number=Sing	_	_	_	_
54	lines	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	recently	_	ADV	_	_	_	_	_	_
4	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	novel	_	NOUN	_	Number=Sing	_	_	_	_
7	APL	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	line	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	UF	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	features	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	RA	_	NOUN	_	Number=Sing	_	_	_	_
19	resistance	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	1,25	_	NUM	_	NumType=Card	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	OH	_	INTJ	_	_	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	2D3	_	NUM	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
8	growth	_	NOUN	_	Number=Sing	_	_	_	_
9	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	G1	_	PROPN	_	Number=Sing	_	_	_	_
12	arrest	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	UF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	toward	_	ADP	_	_	_	_	_	_
26	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	1	_	NUM	_	NumType=Card	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	25	_	NUM	_	NumType=Card	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	OH	_	INTJ	_	_	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	2D3-induced	_	ADJ	_	Number=Sing	_	_	_	_

1	G1	_	PROPN	_	Number=Sing	_	_	_	_
2	arrest	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	all	_	DET	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	trans	_	NOUN	_	Number=Sing	_	_	_	_
9	RA	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Also	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	25	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	OH	_	NOUN	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	2D3	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	10	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	10	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	10	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	-	_	SYM	_	_	_	_	_	_
20	7	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	mol	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	L	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	combination	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	RA	_	PROPN	_	Number=Sing	_	_	_	_
30	markedly	_	ADV	_	_	_	_	_	_
31	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
33	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	dose	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	time	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
42	manner	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	findings	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	p21	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	WAF1	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	CIP1	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	p27	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	KIP1	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	p21	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	WAF1	_	PROPN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	CIP1	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	p27	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	KIP1	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	p21	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	WAF1	_	PROPN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	CIP1	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	p27	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	KIP1	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	after	_	ADP	_	_	_	_	_	_
21	6	_	NUM	_	NumType=Card	_	_	_	_
22	hours	_	NOUN	_	Number=Plur	_	_	_	_
23	'	_	PART	_	_	_	_	_	_
24	exposure	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	1,25	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	OH	_	INTJ	_	_	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	2D3	_	NUM	_	NumType=Card	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	then	_	ADV	_	PronType=Dem	_	_	_	_
33	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	basal	_	ADJ	_	Degree=Pos	_	_	_	_
36	levels	_	NOUN	_	Number=Plur	_	_	_	_
37	over	_	ADP	_	_	_	_	_	_
38	48	_	NUM	_	NumType=Card	_	_	_	_
39	hours	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	p21	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	WAF1	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	CIP1	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	levels	_	NOUN	_	Number=Plur	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	became	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
18	after	_	ADP	_	_	_	_	_	_
19	12	_	NUM	_	NumType=Card	_	_	_	_
20	hours	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	1,25	_	NUM	_	NumType=Card	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	OH	_	NOUN	_	_	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	2D3	_	NUM	_	NumType=Card	_	_	_	_
27	treatment	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	induction	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	p27	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	KIP1	_	PROPN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
37	much	_	ADV	_	_	_	_	_	_
38	more	_	ADV	_	_	_	_	_	_
39	gradual	_	ADJ	_	Degree=Pos	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	UF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	combination	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	25	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	OH	_	NOUN	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	2D3	_	NUM	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	RA	_	PROPN	_	Number=Sing	_	_	_	_
15	markedly	_	ADV	_	_	_	_	_	_
16	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	levels	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	p27	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	KIP1	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	transcript	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	as	_	SCONJ	_	_	_	_	_	_
28	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	levels	_	NOUN	_	Number=Plur	_	_	_	_
31	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	25	_	NUM	_	NumType=Card	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	OH	_	INTJ	_	_	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	2D3	_	NUM	_	NumType=Card	_	_	_	_
40	alone	_	ADV	_	_	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
5	p27	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	KIP1	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	level	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
16	antigen	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
19	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	RA	_	PROPN	_	Number=Sing	_	_	_	_
5	alone	_	ADV	_	_	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
8	G1	_	PROPN	_	Number=Sing	_	_	_	_
9	arrest	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	UF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	;	_	PUNCT	_	_	_	_	_	_
16	however	_	ADV	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
19	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	result	_	VERB	_	VerbForm=Inf	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	increase	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	p21(WAF1	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	CIP1	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	p27	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	KIP1	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	transcript	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	protein	_	VERB	_	Number=Sing	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	RA	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	1,25	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	OH	_	INTJ	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	2D3	_	NUM	_	NumType=Card	_	_	_	_
12	induces	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	cdk	_	NOUN	_	Number=Sing	_	_	_	_
17	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	G1	_	NOUN	_	Number=Sing	_	_	_	_
23	arrest	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
27	may	_	AUX	_	VerbForm=Fin	_	_	_	_
28	be	_	AUX	_	VerbForm=Inf	_	_	_	_
29	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	RA	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
36	UF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	toward	_	ADP	_	_	_	_	_	_
41	mature	_	ADJ	_	Degree=Pos	_	_	_	_
42	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003314	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Effects	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	10	_	NUM	_	NumType=Card	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
9	blood	_	NOUN	_	Number=Sing	_	_	_	_
10	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	responses	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	Cryptococcus	_	PROPN	_	Number=Sing	_	_	_	_
15	neoformans	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	Candida	_	PROPN	_	Number=Sing	_	_	_	_
18	albicans	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Deactivation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	critical	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	limit	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	can	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	detrimental	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	face	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	progressive	_	ADJ	_	Degree=Pos	_	_	_	_
21	infection	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	deactivating	_	NOUN	_	VerbForm=Ger	_	_	_	_
8	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	10	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
19	blood	_	NOUN	_	Number=Sing	_	_	_	_
20	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	responses	_	NOUN	_	Number=Plur	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	LPS	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	Cryptococcus	_	NOUN	_	Number=Sing	_	_	_	_
33	neoformans	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	Candida	_	PROPN	_	Number=Sing	_	_	_	_
37	albicans	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	effected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	dose	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	tumor	_	NOUN	_	Number=Sing	_	_	_	_
11	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TNF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	release	_	VERB	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
22	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	LPS	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	C.	_	PROPN	_	Number=Sing	_	_	_	_
27	neoformans	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	significant	_	ADJ	_	Degree=Pos	_	_	_	_
31	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
32	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	0.1	_	NUM	_	NumType=Card	_	_	_	_
35	U/ml	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
38	than	_	ADP	_	_	_	_	_	_
39	90	_	NUM	_	NumType=Card	_	_	_	_
40	%	_	SYM	_	Number=Sing	_	_	_	_
41	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
42	noted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	with	_	ADP	_	_	_	_	_	_
44	10	_	NUM	_	NumType=Card	_	_	_	_
45	U/ml	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	even	_	ADV	_	_	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	doses	_	NOUN	_	Number=Plur	_	_	_	_
7	as	_	ADV	_	_	_	_	_	_
8	high	_	ADJ	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	100	_	NUM	_	NumType=Card	_	_	_	_
11	U/ml	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	10	_	NUM	_	NumType=Card	_	_	_	_
16	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	TNF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	release	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	C.	_	PROPN	_	Number=Sing	_	_	_	_
25	albicans	_	PROPN	_	Number=Plur	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	only	_	ADV	_	_	_	_	_	_
28	50	_	NUM	_	NumType=Card	_	_	_	_
29	%	_	SYM	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	profoundly	_	ADV	_	_	_	_	_	_
5	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	release	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1beta	_	PROPN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
13	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	all	_	DET	_	_	_	_	_	_
16	three	_	NUM	_	NumType=Card	_	_	_	_
17	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	PROPN	_	Number=Sing	_	_	_	_
4	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	release	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	even	_	ADV	_	_	_	_	_	_
10	if	_	SCONJ	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	10	_	NUM	_	NumType=Card	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	added	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	up	_	ADP	_	_	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	8	_	NUM	_	NumType=Card	_	_	_	_
19	h	_	NOUN	_	Number=Sing	_	_	_	_
20	after	_	ADP	_	_	_	_	_	_
21	cryptococcal	_	ADJ	_	Degree=Pos	_	_	_	_
22	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	beta	_	NOUN	_	Number=Sing	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	lesser	_	ADJ	_	Degree=Cmp	_	_	_	_
14	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	occurred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	only	_	ADV	_	_	_	_	_	_
18	when	_	ADV	_	PronType=Int	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	10	_	NUM	_	NumType=Card	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	added	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	within	_	ADP	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	h	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	cryptococcal	_	ADJ	_	Degree=Pos	_	_	_	_
29	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	translocation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	LPS	_	NOUN	_	Number=Sing	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	fungal	_	ADJ	_	Degree=Pos	_	_	_	_
18	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	three	_	NUM	_	NumType=Card	_	_	_	_
3	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	10	_	NUM	_	NumType=Card	_	_	_	_
8	production	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	although	_	SCONJ	_	_	_	_	_	_
13	over	_	ADV	_	_	_	_	_	_
14	10	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	fold	_	VERB	_	Number=Sing	_	_	_	_
17	less	_	ADV	_	Degree=Cmp	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	10	_	NUM	_	NumType=Card	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	released	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	response	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	C.	_	PROPN	_	Number=Sing	_	_	_	_
27	neoformans	_	NOUN	_	Number=Sing	_	_	_	_
28	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	LPS	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	C.	_	PROPN	_	Number=Sing	_	_	_	_
33	albicans	_	PROPN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	while	_	SCONJ	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	10	_	NUM	_	NumType=Card	_	_	_	_
7	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	deactivating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	effects	_	NOUN	_	Number=Plur	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
12	responses	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	all	_	DET	_	_	_	_	_	_
15	three	_	NUM	_	NumType=Card	_	_	_	_
16	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	disparate	_	ADJ	_	Degree=Pos	_	_	_	_
19	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	patterns	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	deactivation	_	NOUN	_	Number=Sing	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	10	_	NUM	_	NumType=Card	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
9	release	_	NOUN	_	Number=Sing	_	_	_	_
10	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	TNF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	both	_	CCONJ	_	_	_	_	_	_
25	transcriptionally	_	ADV	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	posttranscriptionally	_	ADV	_	_	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1beta	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003316	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	zinc	_	NOUN	_	Number=Sing	_	_	_	_
3	finger	_	NOUN	_	Number=Sing	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	Egr	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	essential	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	restricts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	along	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
18	lineage	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
5	clones	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
8	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	MyD	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	absence	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	de	_	PROPN	_	Number=Sing	_	_	_	_
22	novo	_	NOUN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
25	following	_	VERB	_	VerbForm=Ger	_	_	_	_
26	induction	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
29	along	_	ADP	_	_	_	_	_	_
30	either	_	CCONJ	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
35	lineage	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	human	_	ADJ	_	Degree=Pos	_	_	_	_
38	myeloblastic	_	ADJ	_	Degree=Pos	_	_	_	_
39	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
40	HL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	60	_	NUM	_	NumType=Card	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
3	clone	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	primary	_	ADJ	_	Degree=Pos	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	upon	_	ADP	_	_	_	_	_	_
12	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	Egr	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	zinc	_	NOUN	_	Number=Sing	_	_	_	_
23	finger	_	NOUN	_	Number=Sing	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Egr	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	transcriptionally	_	ADV	_	_	_	_	_	_
11	silent	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	HL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	60	_	NUM	_	NumType=Card	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	but	_	CCONJ	_	_	_	_	_	_
19	active	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	U	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	937	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	M1	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	latter	_	ADJ	_	Degree=Pos	_	_	_	_
30	two	_	NUM	_	NumType=Card	_	_	_	_
31	being	_	AUX	_	VerbForm=Ger	_	_	_	_
32	predetermined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	for	_	ADP	_	_	_	_	_	_
34	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
35	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Egr	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	antisense	_	ADJ	_	Degree=Pos	_	_	_	_
5	oligomers	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	culture	_	NOUN	_	Number=Sing	_	_	_	_
9	media	_	NOUN	_	Number=Sing	_	_	_	_
10	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	both	_	DET	_	_	_	_	_	_
15	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
16	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lines	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	normal	_	ADJ	_	Degree=Pos	_	_	_	_
21	myeloblasts	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	HL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	60	_	NUM	_	NumType=Card	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	constitutively	_	ADV	_	_	_	_	_	_
6	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	Egr	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	transgene	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	HL	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	60	_	NUM	_	NumType=Card	_	_	_	_
16	Egr	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	could	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	not	_	ADV	_	_	_	_	_	_
28	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Egr	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	essential	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	restricts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	myeloblasts	_	NOUN	_	Number=Plur	_	_	_	_
18	along	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
21	lineage	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003321	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	[	_	PUNCT	_	_	_	_	_	_
2	Glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
3	receptors	_	NOUN	_	Number=Plur	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
7	mononuclear	_	ADJ	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	polymorphonuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	leucocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	changes	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	patients	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	yang	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
19	]	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	former	_	ADJ	_	Degree=Pos	_	_	_	_
8	works	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
12	receptors	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	GCR	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
18	mixed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	leucocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	patients	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	Yang	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	work	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	mixed	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
7	leucocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	further	_	ADV	_	_	_	_	_	_
10	separated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	into	_	ADP	_	_	_	_	_	_
12	mononuclear	_	ADJ	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	MNL	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	polymorphonuclear	_	ADJ	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	PML	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	leucocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	GCR	_	NOUN	_	Number=Sing	_	_	_	_
25	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	determined	_	VERB	_	Degree=Pos	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	each	_	DET	_	_	_	_	_	_
29	part	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	leucocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	GCR	_	NOUN	_	Number=Sing	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	MNL	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	PML	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	6	_	NUM	_	NumType=Card	_	_	_	_
8	Yang	_	PROPN	_	Number=Sing	_	_	_	_
9	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
10	patients	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	3473	_	NUM	_	NumType=Card	_	_	_	_
13	+/-	_	SYM	_	_	_	_	_	_
14	413	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	4433	_	NUM	_	NumType=Card	_	_	_	_
17	+/-	_	SYM	_	_	_	_	_	_
18	651	_	NUM	_	NumType=Card	_	_	_	_
19	sites	_	NOUN	_	Number=Plur	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	respectively	_	ADV	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	statistically	_	ADV	_	_	_	_	_	_
25	significant	_	ADJ	_	Degree=Pos	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	normal	_	ADJ	_	Degree=Pos	_	_	_	_
29	control	_	NOUN	_	Number=Sing	_	_	_	_
30	group	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	4462	_	NUM	_	NumType=Card	_	_	_	_
33	+/-	_	SYM	_	_	_	_	_	_
34	962	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	5622	_	NUM	_	NumType=Card	_	_	_	_
37	+/-	_	SYM	_	_	_	_	_	_
38	782	_	NUM	_	NumType=Card	_	_	_	_
39	sites	_	NOUN	_	Number=Plur	_	_	_	_
40	/	_	PUNCT	_	_	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	respectively	_	ADV	_	_	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	P	_	NOUN	_	Number=Sing	_	_	_	_
45	less	_	ADJ	_	Degree=Cmp	_	_	_	_
46	than	_	ADP	_	_	_	_	_	_
47	0.05	_	NUM	_	NumType=Card	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	GCR	_	NOUN	_	Number=Sing	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	MNL	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	PML	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	mixed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	leucocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	5	_	NUM	_	NumType=Card	_	_	_	_
11	patients	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	simultaneously	_	ADV	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	all	_	ADV	_	_	_	_	_	_
18	lowered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	control	_	NOUN	_	Number=Sing	_	_	_	_
22	group	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	3369	_	NUM	_	NumType=Card	_	_	_	_
5	+/-	_	SYM	_	_	_	_	_	_
6	370	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	4986	_	NUM	_	NumType=Card	_	_	_	_
9	+/-	_	SYM	_	_	_	_	_	_
10	419	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	4524	_	NUM	_	NumType=Card	_	_	_	_
13	+/-	_	SYM	_	_	_	_	_	_
14	852	_	NUM	_	NumType=Card	_	_	_	_
15	sites	_	NOUN	_	Number=Plur	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	respectively	_	ADV	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	lowest	_	ADJ	_	Degree=Sup	_	_	_	_
23	GCR	_	NOUN	_	Number=Sing	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	MNL	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	highest	_	ADJ	_	Degree=Sup	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	PML	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003324	_	NUM	_	NumType=Card	_	_	_	_
3	ends.	_	NOUN	_	Number=Sing	_	_	_	_
4	p70	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	s6k	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	integrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	phosphatidylinositol	_	NOUN	_	Number=Sing	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	signals	_	NOUN	_	Number=Plur	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	E2F	_	PROPN	_	Number=Sing	_	_	_	_
20	regulation	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	_	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	uses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	phosphatidylinositol	_	NOUN	_	Number=Sing	_	_	_	_
18	3	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	PI	_	NOUN	_	Number=Sing	_	_	_	_
23	3	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kinase	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	signaling	_	NOUN	_	Number=Sing	_	_	_	_
30	pathways	_	NOUN	_	Number=Plur	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
33	E2F	_	NOUN	_	Number=Sing	_	_	_	_
34	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
35	activity	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	critical	_	ADJ	_	Degree=Pos	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	cycle	_	NOUN	_	Number=Sing	_	_	_	_
41	checkpoint	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	PI	_	NOUN	_	Number=Sing	_	_	_	_
2	3	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	p70	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	s6k	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	40S	_	NOUN	_	Number=Plur	_	_	_	_
17	ribosomal	_	PROPN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_

1	S6	_	PROPN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	response	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	abrogated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	macrolide	_	ADJ	_	Number=Sing	_	_	_	_
12	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
3	drug	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
8	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
9	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	precise	_	ADJ	_	Degree=Pos	_	_	_	_
14	point	_	NOUN	_	Number=Sing	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	which	_	DET	_	PronType=Rel	_	_	_	_
17	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
18	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
20	cycle	_	NOUN	_	Number=Sing	_	_	_	_
21	progression	_	NOUN	_	Number=Sing	_	_	_	_
22	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	yet	_	ADV	_	_	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	elucidated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADV	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	p70	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	s6k	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	in	_	ADV	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	PI	_	NOUN	_	Number=Sing	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kinase	_	NOUN	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	E2Fs	_	NOUN	_	Number=Plur	_	_	_	_
30	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	not	_	PART	_	_	_	_	_	_
32	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
33	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	results	_	NOUN	_	Number=Plur	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	PI	_	NOUN	_	Number=Sing	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kinase	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	pathways	_	NOUN	_	Number=Plur	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	regulation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	E2F	_	PROPN	_	Number=Sing	_	_	_	_
23	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	both	_	CCONJ	_	_	_	_	_	_
27	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	resistant	_	NOUN	_	Degree=Pos	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	rapamycin	_	ADJ	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
34	components	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
7	mutant	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	p70	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	s6k	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	could	_	AUX	_	VerbForm=Fin	_	_	_	_
17	restore	_	VERB	_	VerbForm=Inf	_	_	_	_
18	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	E2F	_	NOUN	_	Number=Sing	_	_	_	_
22	responses	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	processes	_	NOUN	_	Number=Plur	_	_	_	_
8	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	E2F	_	PROPN	_	Number=Sing	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	p70	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	s6k	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	resistant	_	NOUN	_	Number=Sing	_	_	_	_
7	p70	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	s6k	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	could	_	AUX	_	VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	rescue	_	VERB	_	VerbForm=Inf	_	_	_	_
14	rapamycin	_	NOUN	_	Degree=Pos	_	_	_	_
15	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
18	cycle	_	NOUN	_	Number=Sing	_	_	_	_
19	entry	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	involvement	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	additional	_	ADJ	_	Degree=Pos	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	rapamycin	_	ADJ	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
31	pathways	_	NOUN	_	Number=Plur	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	control	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
37	cycle	_	NOUN	_	Number=Sing	_	_	_	_
38	progression	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	results	_	NOUN	_	Number=Plur	_	_	_	_
4	thus	_	ADV	_	_	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	p70(s6k	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	able	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	E2F	_	NOUN	_	Number=Sing	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
18	direct	_	ADJ	_	Degree=Pos	_	_	_	_
19	evidence	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
23	time	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	link	_	NOUN	_	Number=Sing	_	_	_	_
27	between	_	ADP	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	receptors	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	PI	_	NOUN	_	Number=Sing	_	_	_	_
34	3	_	NUM	_	NumType=Card	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kinase	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	p70	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	s6k	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	that	_	PRON	_	PronType=Rel	_	_	_	_
44	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
46	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
47	G1	_	NOUN	_	Number=Sing	_	_	_	_
48	checkpoint	_	NOUN	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	T	_	PROPN	_	Number=Sing	_	_	_	_
51	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003327	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	USF	_	PROPN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	c	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	Myc	_	PROPN	_	Number=Sing	_	_	_	_
6	enhances	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	while	_	SCONJ	_	_	_	_	_	_
9	Yin	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	Yang	_	PROPN	_	Number=Sing	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	suppresses	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	CXCR4	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	coreceptor	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	HIV	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	entry	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	USF1	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	USF2	_	PROPN	_	Number=Sing	_	_	_	_
6	up	_	ADP	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	regulate	_	VERB	_	Degree=Pos	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	i.e.	_	X	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	HIV	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	long	_	ADJ	_	Degree=Pos	_	_	_	_
18	terminal	_	NOUN	_	Number=Sing	_	_	_	_
19	repeats	_	NOUN	_	Number=Plur	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	via	_	ADP	_	_	_	_	_	_
22	interaction	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	E	_	NOUN	_	Number=Sing	_	_	_	_
26	box	_	NOUN	_	Number=Sing	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
29	target	_	NOUN	_	Number=Sing	_	_	_	_
30	promoters	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	also	_	ADV	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	binding	_	NOUN	_	Number=Sing	_	_	_	_
37	site	_	NOUN	_	Number=Sing	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	c	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	Myc	_	PROPN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	c-Myc	_	PROPN	_	Number=Sing	_	_	_	_
3	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	control	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	while	_	SCONJ	_	_	_	_	_	_
15	Yin	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	Yang	_	PROPN	_	Number=Sing	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	YY1	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	control	_	VERB	_	VerbForm=Inf	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	number	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	viral	_	ADJ	_	Degree=Pos	_	_	_	_
36	genes	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	physically	_	ADV	_	_	_	_	_	_
5	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	each	_	DET	_	_	_	_	_	_
8	other	_	ADJ	_	Degree=Pos	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	mutually	_	ADV	_	_	_	_	_	_
11	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	respective	_	ADJ	_	Degree=Pos	_	_	_	_
14	biological	_	ADJ	_	Degree=Pos	_	_	_	_
15	functions	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	USF	_	PROPN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	c-Myc	_	NOUN	_	Number=Sing	_	_	_	_
11	up	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	regulates	_	VERB	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	while	_	SCONJ	_	_	_	_	_	_
16	YY1	_	PROPN	_	Number=Sing	_	_	_	_
17	down	_	ADV	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	CXCR4	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	coreceptor	_	NOUN	_	Number=Sing	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	T	_	PROPN	_	Number=Sing	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	tropic	_	ADJ	_	Degree=Pos	_	_	_	_
33	HIV	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	entry	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	E	_	NOUN	_	Number=Sing	_	_	_	_
6	box	_	NOUN	_	Number=Sing	_	_	_	_
7	around	_	ADV	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	260	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	YY1	_	PROPN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	around	_	ADV	_	_	_	_	_	_
16	-	_	SYM	_	_	_	_	_	_
17	300	_	NUM	_	NumType=Card	_	_	_	_
18	relative	_	ADV	_	_	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	start	_	NOUN	_	Number=Sing	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	E	_	NOUN	_	Number=Sing	_	_	_	_
5	box	_	NOUN	_	Number=Sing	_	_	_	_
6	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	USF	_	PROPN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	c-Myc	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	up	_	ADP	_	_	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	CXCR4	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	mutation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	YY1	_	PROPN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	site	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	unresponsiveness	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	YY1	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
35	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	USF	_	PROPN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	c-Myc	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	YY1	_	PROPN	_	Number=Sing	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	play	_	VERB	_	VerbForm=Inf	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	important	_	ADJ	_	Degree=Pos	_	_	_	_
14	role	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	HIV	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	replicative	_	ADJ	_	Degree=Pos	_	_	_	_
22	cycle	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	by	_	SCONJ	_	_	_	_	_	_
25	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
26	both	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	viral	_	ADJ	_	Degree=Pos	_	_	_	_
29	fusion	_	NOUN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	entry	_	NOUN	_	Number=Sing	_	_	_	_
32	process	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	viral	_	ADJ	_	Degree=Pos	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003329	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcriptionally	_	ADV	_	_	_	_	_	_
3	active	_	ADJ	_	Degree=Pos	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	Tax	_	NOUN	_	Number=Sing	_	_	_	_
14	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2R	_	NOUN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	PROPN	_	Number=Sing	_	_	_	_
23	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
24	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	product	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
30	proto	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
3	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	Tax	_	NOUN	_	Number=Sing	_	_	_	_
7	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	coding	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	chain	_	NOUN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2R	_	NOUN	_	Number=Sing	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	via	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	site	_	NOUN	_	Number=Sing	_	_	_	_
33	that	_	PRON	_	PronType=Rel	_	_	_	_
34	can	_	AUX	_	VerbForm=Fin	_	_	_	_
35	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
36	several	_	ADJ	_	Degree=Pos	_	_	_	_
37	protein	_	NOUN	_	Number=Sing	_	_	_	_
38	species	_	NOUN	_	Number=Plur	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	rel	_	PROPN	_	Number=Sing	_	_	_	_
42	family	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Tax1	_	NOUN	_	Number=Sing	_	_	_	_
2	strongly	_	ADV	_	_	_	_	_	_
3	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	motif	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
14	HeLa	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	lymphoid	_	VERB	_	Number=Sing	_	_	_	_
17	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	undifferentiated	_	ADJ	_	Degree=Pos	_	_	_	_
8	embryocarcinoma	_	PROPN	_	Number=Sing	_	_	_	_
9	F9	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	p50	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	p65	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Rel	_	NOUN	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	significant	_	ADJ	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2R	_	NOUN	_	Number=Sing	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	only	_	ADV	_	_	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	Rel	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	Rel	_	PROPN	_	Number=Sing	_	_	_	_
33	plus	_	CCONJ	_	_	_	_	_	_
34	p65	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	whereas	_	SCONJ	_	_	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	Tax	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
8	12	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	myristate	_	NOUN	_	Number=Sing	_	_	_	_
11	13	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	acetate	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	PMA	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	able	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	efficiently	_	ADV	_	_	_	_	_	_
21	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2R	_	PROPN	_	Number=Sing	_	_	_	_
34	alpha	_	NOUN	_	Number=Sing	_	_	_	_
35	kappa	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	PROPN	_	Number=Sing	_	_	_	_
37	site	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	PMA	_	PROPN	_	Number=Sing	_	_	_	_
40	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	functionally	_	ADV	_	_	_	_	_	_
42	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	affinity	_	NOUN	_	Number=Sing	_	_	_	_
5	precipitation	_	NOUN	_	Number=Sing	_	_	_	_
6	assay	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	Tax1	_	PROPN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	able	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	efficiently	_	ADV	_	_	_	_	_	_
16	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Rel	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	whereas	_	SCONJ	_	_	_	_	_	_
23	PMA	_	PROPN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	established	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	clear	_	ADJ	_	Degree=Pos	_	_	_	_
5	difference	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	both	_	CCONJ	_	_	_	_	_	_
8	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	Rel	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	functionally	_	ADV	_	_	_	_	_	_
16	active	_	ADJ	_	Degree=Pos	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	functional	_	ADJ	_	Degree=Pos	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	members	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	rel	_	PROPN	_	Number=Sing	_	_	_	_
15	family	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	interaction	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	DNA	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	Rel	_	PROPN	_	Number=Sing	_	_	_	_
26	can	_	AUX	_	VerbForm=Fin	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	potent	_	NOUN	_	Degree=Pos	_	_	_	_
30	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
31	activator	_	NOUN	_	Number=Sing	_	_	_	_
32	on	_	ADP	_	_	_	_	_	_
33	specific	_	ADJ	_	Degree=Pos	_	_	_	_
34	kappa	_	NOUN	_	Number=Sing	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	sites	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003330	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	functional	_	ADJ	_	Degree=Pos	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	endometrium	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	endometriosis	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	aetiology	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	endometriosis	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	common	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	disabling	_	ADJ	_	Degree=Pos	_	_	_	_
10	disorder	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	presently	_	ADV	_	_	_	_	_	_
14	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	although	_	SCONJ	_	_	_	_	_	_
17	immune	_	ADJ	_	Degree=Pos	_	_	_	_
18	dysfunction	_	NOUN	_	Number=Sing	_	_	_	_
19	could	_	AUX	_	VerbForm=Fin	_	_	_	_
20	allow	_	VERB	_	VerbForm=Inf	_	_	_	_
21	ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
22	endometrial	_	ADJ	_	Degree=Pos	_	_	_	_
23	fragments	_	NOUN	_	Number=Plur	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	survive	_	VERB	_	VerbForm=Inf	_	_	_	_
26	outside	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	uterine	_	NOUN	_	Number=Sing	_	_	_	_
29	cavity	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	investigate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	relationship	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	leukocyte	_	ADJ	_	Degree=Pos	_	_	_	_
8	populations	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	steroid	_	ADJ	_	Degree=Pos	_	_	_	_
11	hormone	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	bcl	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	eutopic	_	ADJ	_	Degree=Pos	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
28	endometrium	_	NOUN	_	Number=Sing	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	women	_	NOUN	_	Number=Plur	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	endometriosis	_	NOUN	_	Number=Sing	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	adenomyosis	_	NOUN	_	Number=Sing	_	_	_	_
35	at	_	ADP	_	_	_	_	_	_
36	different	_	ADJ	_	Degree=Pos	_	_	_	_
37	phases	_	NOUN	_	Number=Plur	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	menstrual	_	ADJ	_	Degree=Pos	_	_	_	_
41	cycle	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Significantly	_	ADV	_	_	_	_	_	_
2	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	oestrogen	_	NOUN	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	bcl	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	numbers	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	CD8	_	NOUN	_	Number=Sing	_	_	_	_
15	+	_	SYM	_	_	_	_	_	_
16	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
21	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	eutopic	_	ADJ	_	Degree=Pos	_	_	_	_
24	endometrium	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	endometriosis	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	CD56	_	PROPN	_	Number=Sing	_	_	_	_
30	+	_	SYM	_	_	_	_	_	_
31	endometrial	_	ADJ	_	Degree=Pos	_	_	_	_
32	granulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	eGLs	_	NOUN	_	Number=Plur	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	significantly	_	ADV	_	_	_	_	_	_
39	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
42	endometrium	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	rarely	_	ADV	_	_	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	control	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	subject	_	ADJ	_	Number=Sing	_	_	_	_
10	endometria	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	endometriosis	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	adenomyotic	_	ADJ	_	Degree=Pos	_	_	_	_
7	lesions	_	NOUN	_	Number=Plur	_	_	_	_
8	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	identical	_	ADJ	_	Degree=Pos	_	_	_	_
10	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
11	hormone	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	bcl	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	leukocyte	_	ADJ	_	Degree=Pos	_	_	_	_
24	subpopulations	_	NOUN	_	Number=Plur	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	eutopic	_	VERB	_	Degree=Pos	_	_	_	_
27	endometrium	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
30	different	_	ADJ	_	Degree=Pos	_	_	_	_
31	aetiologies	_	NOUN	_	Number=Plur	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
34	disorders	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	unusual	_	ADJ	_	Degree=Pos	_	_	_	_
3	CD56	_	NOUN	_	Number=Sing	_	_	_	_
4	+	_	SYM	_	_	_	_	_	_
5	CD16	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	eGLs	_	NOUN	_	Number=Plur	_	_	_	_
8	present	_	VERB	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	large	_	ADJ	_	Degree=Pos	_	_	_	_
11	numbers	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	late	_	ADJ	_	Degree=Pos	_	_	_	_
14	secretory	_	ADJ	_	Number=Sing	_	_	_	_
15	phase	_	NOUN	_	Number=Sing	_	_	_	_
16	eutopic	_	ADJ	_	Degree=Pos	_	_	_	_
17	endometrium	_	NOUN	_	Number=Sing	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	highly	_	ADV	_	_	_	_	_	_
20	purified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	>	_	PUNCT	_	_	_	_	_	_
23	98	_	NUM	_	NumType=Card	_	_	_	_
24	%	_	SYM	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	immunomagnetic	_	ADJ	_	Degree=Pos	_	_	_	_
28	separation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Except	_	ADP	_	_	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	negligible	_	ADJ	_	Degree=Pos	_	_	_	_
5	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	eGLs	_	NOUN	_	Number=Plur	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	early	_	ADJ	_	Degree=Pos	_	_	_	_
11	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
12	samples	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	eGLs	_	NOUN	_	Number=Plur	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	non-pregnant	_	ADJ	_	Degree=Pos	_	_	_	_
20	endometrium	_	NOUN	_	Number=Sing	_	_	_	_
21	during	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	menstrual	_	ADJ	_	Degree=Pos	_	_	_	_
24	cycle	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
31	blood	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	predominantly	_	ADV	_	_	_	_	_	_
34	CD56	_	NOUN	_	Number=Sing	_	_	_	_
35	+	_	SYM	_	_	_	_	_	_
36	CD16	_	PROPN	_	Number=Sing	_	_	_	_
37	+	_	SYM	_	_	_	_	_	_
38	natural	_	ADJ	_	Degree=Pos	_	_	_	_
39	killer	_	NOUN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	eGLs	_	NOUN	_	Number=Plur	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	non-pregnant	_	ADJ	_	Degree=Pos	_	_	_	_
4	endometrium	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	early	_	ADJ	_	Degree=Pos	_	_	_	_
7	pregnancy	_	NOUN	_	Number=Sing	_	_	_	_
8	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	variable	_	ADJ	_	Degree=Pos	_	_	_	_
11	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	5	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	100	_	NUM	_	NumType=Card	_	_	_	_
17	U	_	PROPN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	ml	_	NUM	_	Number=Sing	_	_	_	_
20	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	over	_	ADV	_	_	_	_	_	_
24	48	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	h	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	120	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	SYM	_	_	_	_	_	_
30	h	_	NOUN	_	NumType=Card	_	_	_	_
31	time	_	NOUN	_	Number=Sing	_	_	_	_
32	courses	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	eGLs	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	evidently	_	ADV	_	_	_	_	_	_
4	functionally	_	ADV	_	_	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	eutopic	_	ADJ	_	Degree=Pos	_	_	_	_
9	endometrium	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	absence	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	endometriotic	_	ADJ	_	Degree=Pos	_	_	_	_
5	lesions	_	NOUN	_	Number=Plur	_	_	_	_
6	together	_	ADV	_	_	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	CD+8	_	NOUN	_	Number=Sing	_	_	_	_
10	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
11	numbers	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	oestrogen	_	NOUN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	bcl	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	may	_	AUX	_	VerbForm=Fin	_	_	_	_
22	have	_	VERB	_	VerbForm=Inf	_	_	_	_
23	significant	_	ADJ	_	Degree=Pos	_	_	_	_
24	effects	_	NOUN	_	Number=Plur	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	development	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	progression	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	endometriosis	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003333	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
6	signal	_	NOUN	_	Number=Sing	_	_	_	_
7	transducer	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	activator	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	STAT	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	pathway	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	asthma	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Cytokine	_	NOUN	_	Number=Sing	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	immunity	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
7	often	_	ADV	_	_	_	_	_	_
8	depend	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	signal	_	NOUN	_	Number=Sing	_	_	_	_
15	transducers	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	activators	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	STATs	_	NOUN	_	Number=Plur	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	so	_	ADV	_	_	_	_	_	_
25	STAT	_	NOUN	_	Number=Sing	_	_	_	_
26	signaling	_	NOUN	_	Number=Sing	_	_	_	_
27	pathways	_	NOUN	_	Number=Plur	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	candidates	_	NOUN	_	Number=Plur	_	_	_	_
30	for	_	SCONJ	_	_	_	_	_	_
31	influencing	_	VERB	_	VerbForm=Ger	_	_	_	_
32	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
33	disease	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	reasoned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	selective	_	ADJ	_	Degree=Pos	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
10	STAT	_	PROPN	_	Number=Sing	_	_	_	_
11	family	_	NOUN	_	Number=Sing	_	_	_	_
12	member	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	immune	_	ADJ	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	such	_	ADJ	_	Degree=Pos	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
27	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
28	molecule	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	IFN	_	PROPN	_	Number=Sing	_	_	_	_
38	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
39	factor	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	IRF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
50	itself	_	PRON	_	Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
51	in	_	ADP	_	_	_	_	_	_
52	airway	_	PROPN	_	Degree=Pos	_	_	_	_
53	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
54	cells	_	NOUN	_	Number=Plur	_	_	_	_
55	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
56	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
57	basis	_	NOUN	_	Number=Sing	_	_	_	_
58	for	_	SCONJ	_	_	_	_	_	_
59	detecting	_	VERB	_	VerbForm=Ger	_	_	_	_
60	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
61	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
62	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
63	in	_	ADP	_	_	_	_	_	_
64	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
65	airway	_	NOUN	_	Number=Sing	_	_	_	_
66	disease	_	NOUN	_	Number=Sing	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	basis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	localization	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
14	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	not	_	ADV	_	_	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	control	_	NOUN	_	Number=Sing	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	invariably	_	ADV	_	_	_	_	_	_
25	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	asthmatic	_	ADJ	_	Degree=Pos	_	_	_	_
28	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	normal	_	ADJ	_	Degree=Pos	_	_	_	_
31	control	_	NOUN	_	Number=Sing	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	chronic	_	ADJ	_	Number=Sing	_	_	_	_
34	bronchitis	_	NOUN	_	Number=Sing	_	_	_	_
35	subjects	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
8	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
15	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	IRF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	turn	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	levels	_	NOUN	_	Number=Plur	_	_	_	_
34	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
37	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	tissue	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	only	_	ADV	_	_	_	_	_	_
4	low	_	ADJ	_	Degree=Pos	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	gamma	_	NOUN	_	Number=Sing	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	IFN	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	airway	_	NOUN	_	Number=Sing	_	_	_	_
21	tissue	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	all	_	DET	_	_	_	_	_	_
24	subjects	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	therefore	_	ADV	_	_	_	_	_	_
4	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	initial	_	ADJ	_	Degree=Pos	_	_	_	_
6	evidence	_	NOUN	_	Number=Sing	_	_	_	_
7	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
8	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
9	behavior	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	STAT	_	NOUN	_	Number=Sing	_	_	_	_
12	pathways	_	NOUN	_	Number=Plur	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
15	signaling	_	VERB	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	development	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	disease	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	context	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	results	_	NOUN	_	Number=Plur	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	change	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	current	_	ADJ	_	Degree=Pos	_	_	_	_
11	scheme	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	asthma	_	NOUN	_	Number=Sing	_	_	_	_
14	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	one	_	NUM	_	NumType=Card	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	must	_	AUX	_	VerbForm=Fin	_	_	_	_
19	include	_	VERB	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	localized	_	ADJ	_	Degree=Pos	_	_	_	_
22	gain	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	signal	_	NOUN	_	Number=Sing	_	_	_	_
26	ordinarily	_	ADV	_	_	_	_	_	_
27	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	T	_	NOUN	_	Number=Sing	_	_	_	_
31	helper	_	NOUN	_	Number=Sing	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	type	_	NOUN	_	Number=Sing	_	_	_	_
35	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	IFN	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	gamma	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	combination	_	NOUN	_	Number=Sing	_	_	_	_
43	with	_	ADP	_	_	_	_	_	_
44	allergy	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	overproduction	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	T	_	NOUN	_	Number=Sing	_	_	_	_
50	helper	_	NOUN	_	Number=Sing	_	_	_	_
51	2	_	NUM	_	NumType=Card	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	type	_	NOUN	_	Number=Sing	_	_	_	_
54	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003335	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	c	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Akt	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	phosphatidylinositol	_	NOUN	_	Number=Sing	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	STAT5	_	NOUN	_	Number=Plur	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	EPO	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	HCD57	_	NOUN	_	Number=Sing	_	_	_	_
26	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	but	_	CCONJ	_	_	_	_	_	_
29	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	constitutively	_	ADV	_	_	_	_	_	_
31	active	_	ADJ	_	Degree=Pos	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	EPO	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	independent	_	ADJ	_	Degree=Pos	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
41	subclone	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	HCD57	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	SREI	_	NOUN	_	Number=Sing	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EPO	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	stem	_	NOUN	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	SCF	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	PKB	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	Akt	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	EPO	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	HCD57	_	NOUN	_	Number=Sing	_	_	_	_
29	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	To	_	ADP	_	_	_	_	_	_
2	better	_	ADV	_	Degree=Cmp	_	_	_	_
3	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
4	signals	_	NOUN	_	Number=Plur	_	_	_	_
5	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
6	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	viability	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	resist	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	absence	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	EPO	_	NOUN	_	Number=Sing	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	subcloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	HCD57	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	SREI	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	activations	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	PKB	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	Akt	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	STAT5a	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	STAT5b	_	PROPN	_	Number=Sing	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	noted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
16	EPO	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	independent	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	PI3	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kinase	_	NOUN	_	Number=Sing	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
8	activator	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	PKB	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	Akt	_	NOUN	_	Number=Sing	_	_	_	_
13	because	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	PI3	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
19	LY294002	_	PROPN	_	Number=Sing	_	_	_	_
20	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	both	_	CCONJ	_	_	_	_	_	_
22	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
23	PKB	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	Akt	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
30	PKB	_	NOUN	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	Akt	_	NOUN	_	Number=Sing	_	_	_	_
33	activity	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	LY294002	_	PROPN	_	Number=Sing	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	viability	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	HCD57	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	SREI	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	HCD57	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	PKB	_	PROPN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	Akt	_	NOUN	_	Number=Sing	_	_	_	_
25	;	_	PUNCT	_	_	_	_	_	_
26	however	_	ADV	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	PKB	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	Akt	_	PROPN	_	Number=Sing	_	_	_	_
31	activity	_	NOUN	_	Number=Sing	_	_	_	_
32	alone	_	ADV	_	_	_	_	_	_
33	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	protect	_	VERB	_	VerbForm=Inf	_	_	_	_
36	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	from	_	ADP	_	_	_	_	_	_
39	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HCD57	_	NOUN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	SCF	_	PROPN	_	Number=Sing	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	PKB	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	Akt	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	protect	_	VERB	_	VerbForm=Inf	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	result	_	NOUN	_	Number=Sing	_	_	_	_
3	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	PKB	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	PI3	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
18	viability	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	through	_	ADP	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
9	pathway	_	NOUN	_	Number=Sing	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	including	_	VERB	_	VerbForm=Ger	_	_	_	_
12	JAK2	_	PROPN	_	Number=Sing	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	EPOR	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	act	_	VERB	_	VerbForm=Inf	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	concert	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
23	PI3	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kinase	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	PKB	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	Akt	_	PROPN	_	Number=Sing	_	_	_	_
30	pathway	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	protect	_	VERB	_	VerbForm=Inf	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	EPO	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	independent	_	ADJ	_	Degree=Pos	_	_	_	_
37	HCD57	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	SREI	_	PROPN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	from	_	ADP	_	_	_	_	_	_
42	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
45	limited	_	ADJ	_	Degree=Pos	_	_	_	_
46	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003337	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Clonality	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	hypereosinophilic	_	ADJ	_	Degree=Pos	_	_	_	_
8	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	idiopathic	_	ADJ	_	Degree=Pos	_	_	_	_
3	hypereosinophilic	_	ADJ	_	Number=Sing	_	_	_	_
4	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	IHES	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	rare	_	ADJ	_	Degree=Pos	_	_	_	_
11	disorder	_	NOUN	_	Number=Sing	_	_	_	_
12	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	unexplained	_	ADJ	_	Degree=Pos	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
17	eosinophilia	_	NOUN	_	Number=Sing	_	_	_	_
18	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
21	organ	_	NOUN	_	Degree=Pos	_	_	_	_
22	dysfunction	_	NOUN	_	Number=Sing	_	_	_	_
23	due	_	ADP	_	_	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	eosinophilic	_	ADJ	_	Degree=Pos	_	_	_	_
26	tissue	_	NOUN	_	Number=Sing	_	_	_	_
27	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	absence	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	karyotypic	_	ADJ	_	Degree=Pos	_	_	_	_
6	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	there	_	PRON	_	_	_	_	_	_
9	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	no	_	DET	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	test	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	detect	_	VERB	_	VerbForm=Inf	_	_	_	_
15	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
16	eosinophilia	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	IHES	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	X	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	chromosome	_	NOUN	_	Degree=Pos	_	_	_	_
6	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
7	patterns	_	NOUN	_	Number=Plur	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
13	whether	_	SCONJ	_	_	_	_	_	_
14	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
15	disorders	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	origin	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Methylation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HpaII	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Hha	_	PROPN	_	Number=Sing	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	sites	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	near	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	polymorphic	_	ADJ	_	Degree=Pos	_	_	_	_
11	trinucleotide	_	NOUN	_	Number=Sing	_	_	_	_
12	repeat	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	androgen	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	HUMARA	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	correlate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	X	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
10	chain	_	NOUN	_	Number=Sing	_	_	_	_
11	reaction	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	PCR	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	nested	_	VERB	_	Degree=Pos	_	_	_	_
17	primers	_	NOUN	_	Number=Plur	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
20	X	_	ADP	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
23	patterns	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	HUMARA	_	PROPN	_	Number=Sing	_	_	_	_
27	loci	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	female	_	ADJ	_	Degree=Pos	_	_	_	_
33	patients	_	NOUN	_	Number=Plur	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	eosinophilia	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
2	blood	_	NOUN	_	Number=Sing	_	_	_	_
3	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
8	autofluoresence	_	NOUN	_	Number=Sing	_	_	_	_
9	using	_	VERB	_	VerbForm=Ger	_	_	_	_
10	flow	_	NOUN	_	Number=Sing	_	_	_	_
11	cytometric	_	ADJ	_	Degree=Pos	_	_	_	_
12	sorting	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
2	purified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	female	_	ADJ	_	Degree=Pos	_	_	_	_
6	patient	_	NOUN	_	Number=Sing	_	_	_	_
7	presenting	_	VERB	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	IHES	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	show	_	VERB	_	VerbForm=Inf	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
16	pattern	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	X	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Eosinophil	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	depleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	patient	_	NOUN	_	Number=Sing	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	HUMARA	_	PROPN	_	Number=Sing	_	_	_	_
12	analysis	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	thus	_	ADV	_	_	_	_	_	_
15	excluding	_	VERB	_	VerbForm=Ger	_	_	_	_
16	skewedness	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	random	_	ADJ	_	Degree=Pos	_	_	_	_
19	X-inactivation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	corticosteroid	_	ADJ	_	Degree=Pos	_	_	_	_
3	suppression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	her	_	PRON	_	Gender=Fem|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	eosinophilia	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
11	population	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
14	could	_	AUX	_	VerbForm=Fin	_	_	_	_
15	no	_	ADV	_	_	_	_	_	_
16	longer	_	ADV	_	Degree=Cmp	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	eosinophils	_	NOUN	_	Number=Sing	_	_	_	_
5	purified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	patient	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	Churg	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Strauss	_	PROPN	_	Number=Sing	_	_	_	_
13	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	six	_	NUM	_	NumType=Card	_	_	_	_
17	patients	_	NOUN	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
20	eosinophilias	_	NOUN	_	Number=Plur	_	_	_	_
21	attributed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	allergy	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	parasitic	_	ADJ	_	Degree=Pos	_	_	_	_
26	infection	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	drug	_	NOUN	_	Number=Sing	_	_	_	_
30	reaction	_	NOUN	_	Number=Sing	_	_	_	_
31	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
34	pattern	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	X	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	HUMARA	_	PROPN	_	Number=Sing	_	_	_	_
41	analysis	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	finding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
5	eosinophilia	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	patient	_	NOUN	_	Number=Sing	_	_	_	_
9	presenting	_	VERB	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	IHES	_	NOUN	_	Number=Sing	_	_	_	_
12	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	such	_	ADJ	_	Degree=Pos	_	_	_	_
15	patients	_	NOUN	_	Number=Plur	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	have	_	VERB	_	VerbForm=Inf	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	reality	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	low	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	grade	_	NOUN	_	Number=Sing	_	_	_	_
26	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
27	disorder	_	NOUN	_	Number=Sing	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	can	_	AUX	_	VerbForm=Fin	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	distinguished	_	ADJ	_	Degree=Pos	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
34	eosinophilias	_	NOUN	_	Number=Plur	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	HUMARA	_	PROPN	_	Number=Sing	_	_	_	_
37	analysis	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	method	_	NOUN	_	Number=Sing	_	_	_	_
5	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	monitor	_	VERB	_	VerbForm=Inf	_	_	_	_
11	disease	_	NOUN	_	Number=Sing	_	_	_	_
12	progression	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003338	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Mice	_	NOUN	_	Number=Plur	_	_	_	_
2	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	55	_	NUM	_	NumType=Card	_	_	_	_
6	kd	_	NOUN	_	Number=Sing	_	_	_	_
7	tumor	_	NOUN	_	Number=Sing	_	_	_	_
8	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	endotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
15	shock	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	yet	_	CCONJ	_	_	_	_	_	_
18	succumb	_	VERB	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	L.	_	PROPN	_	Number=Sing	_	_	_	_
21	monocytogenes	_	NOUN	_	Number=Sing	_	_	_	_
22	infection	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
3	biological	_	ADJ	_	Degree=Pos	_	_	_	_
4	activities	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	tumor	_	NOUN	_	Number=Sing	_	_	_	_
7	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	TNF	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	surface	_	NOUN	_	Number=Sing	_	_	_	_
19	receptors	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	55	_	NUM	_	NumType=Card	_	_	_	_
22	kd	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	TNFRp55	_	NUM	_	NumType=Card	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	75	_	NUM	_	NumType=Card	_	_	_	_
28	kd	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	TNFRp75	_	NUM	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	targeting	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	generated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	TNFRp55	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
11	mouse	_	NOUN	_	Number=Sing	_	_	_	_
12	strain	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Cells	_	NOUN	_	Number=Plur	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	TNFRp55-/-	_	PROPN	_	_	_	_	_	_
4	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
5	mice	_	NOUN	_	Number=Plur	_	_	_	_
6	lack	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	TNFRp55	_	NOUN	_	Number=Sing	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	display	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	normal	_	ADJ	_	Degree=Pos	_	_	_	_
13	numbers	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	high	_	ADJ	_	Degree=Pos	_	_	_	_
16	affinity	_	NOUN	_	Number=Sing	_	_	_	_
17	TNFRp75	_	NOUN	_	Number=Sing	_	_	_	_
18	molecules	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Thymocyte	_	NOUN	_	Number=Sing	_	_	_	_
2	development	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	lymphocyte	_	NOUN	_	Degree=Pos	_	_	_	_
5	populations	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	unaltered	_	ADJ	_	Degree=Pos	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
11	deletion	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	potentially	_	ADV	_	_	_	_	_	_
14	self	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	impaired	_	VERB	_	Degree=Pos	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	TNF	_	PROPN	_	Number=Sing	_	_	_	_
4	signaling	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	largely	_	ADV	_	_	_	_	_	_
7	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	as	_	SCONJ	_	_	_	_	_	_
10	judged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	failure	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	TNF	_	PROPN	_	Number=Sing	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	T	_	PROPN	_	Number=Sing	_	_	_	_
24	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	TNFRp55	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
29	mice	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	loss	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TNFRp55	_	NOUN	_	Number=Sing	_	_	_	_
5	function	_	NOUN	_	Number=Sing	_	_	_	_
6	renders	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	mice	_	NOUN	_	Number=Plur	_	_	_	_
8	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	lethal	_	ADJ	_	Degree=Pos	_	_	_	_
11	dosages	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	either	_	CCONJ	_	_	_	_	_	_
14	lipopolysaccharides	_	NOUN	_	Number=Plur	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	S.	_	PROPN	_	Number=Sing	_	_	_	_
17	aureus	_	NOUN	_	Number=Sing	_	_	_	_
18	enterotoxin	_	NOUN	_	Number=Sing	_	_	_	_
19	B.	_	PROPN	_	Number=Sing	_	_	_	_
20	In	_	ADP	_	_	_	_	_	_
21	contrast	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	TNFRp55	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
26	mice	_	NOUN	_	Number=Plur	_	_	_	_
27	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	severely	_	ADV	_	_	_	_	_	_
29	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	clear	_	VERB	_	VerbForm=Inf	_	_	_	_
32	L.	_	PROPN	_	Number=Sing	_	_	_	_
33	monocytogenes	_	NOUN	_	Number=Plur	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	readily	_	ADV	_	_	_	_	_	_
36	succumb	_	VERB	_	VerbForm=Inf	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	infection	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	55	_	NUM	_	NumType=Card	_	_	_	_
5	kd	_	NOUN	_	Number=Sing	_	_	_	_
6	TNFR	_	PROPN	_	Number=Sing	_	_	_	_
7	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	decisive	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	host	_	NOUN	_	Number=Sing	_	_	_	_
14	's	_	PART	_	_	_	_	_	_
15	defense	_	NOUN	_	Number=Sing	_	_	_	_
16	against	_	ADP	_	_	_	_	_	_
17	microorganisms	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	pathogenic	_	ADJ	_	Degree=Pos	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003339	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	T	_	NOUN	_	_	_	_	_	_
2	helper	_	VERB	_	Number=Sing	_	_	_	_
3	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
4	proceeds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	through	_	ADP	_	_	_	_	_	_
6	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	Stat4	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	Stat4	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	independent	_	ADJ	_	Degree=Pos	_	_	_	_
17	phases	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Much	_	ADJ	_	Degree=Pos	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	focus	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	understanding	_	ADJ	_	VerbForm=Ger	_	_	_	_
7	Th1	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	development	_	NOUN	_	Number=Sing	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	signals	_	NOUN	_	Number=Plur	_	_	_	_
16	delivered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	12	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	final	_	ADJ	_	Degree=Pos	_	_	_	_
27	determinants	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
30	T	_	NOUN	_	Number=Sing	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	extinction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	12	_	NUM	_	NumType=Card	_	_	_	_
7	signaling	_	VERB	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	early	_	ADJ	_	Degree=Pos	_	_	_	_

1	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	development	_	NOUN	_	Number=Sing	_	_	_	_
3	could	_	AUX	_	VerbForm=Fin	_	_	_	_
4	potentially	_	ADV	_	_	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	important	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	SCONJ	_	_	_	_	_	_
8	imprinting	_	VERB	_	VerbForm=Ger	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	more	_	ADV	_	_	_	_	_	_
11	permanent	_	ADJ	_	Degree=Pos	_	_	_	_

1	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	population	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	various	_	ADJ	_	Degree=Pos	_	_	_	_
15	parameters	_	NOUN	_	Number=Plur	_	_	_	_
16	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	12	_	NUM	_	NumType=Card	_	_	_	_
21	signaling	_	NOUN	_	Number=Sing	_	_	_	_
22	pathway	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	4	_	NUM	_	NumType=Card	_	_	_	_
5	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	repress	_	VERB	_	VerbForm=Inf	_	_	_	_
8	functional	_	ADJ	_	Degree=Pos	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	12	_	NUM	_	NumType=Card	_	_	_	_
12	signaling	_	VERB	_	Number=Sing	_	_	_	_
13	through	_	ADP	_	_	_	_	_	_
14	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	12R	_	NUM	_	NumType=Card	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	IFN	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	gamma	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	mouse	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	IFN	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	human	_	ADJ	_	Degree=Pos	_	_	_	_
37	appear	_	NOUN	_	Number=Sing	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	12R	_	NUM	_	NumType=Card	_	_	_	_
43	beta	_	NOUN	_	Number=Sing	_	_	_	_
44	2	_	NUM	_	NumType=Card	_	_	_	_
45	expression	_	NOUN	_	Number=Sing	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
48	IL	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	12	_	NUM	_	NumType=Card	_	_	_	_
51	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	development	_	NOUN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	considered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	stages	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	capacitance	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	development	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Capacitance	_	NOUN	_	Number=Sing	_	_	_	_
2	would	_	AUX	_	VerbForm=Fin	_	_	_	_
3	simply	_	ADV	_	_	_	_	_	_
4	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	12R	_	NUM	_	Number=Sing	_	_	_	_
10	beta	_	NOUN	_	Number=Sing	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	subunits	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	TCR	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	4	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	IFNs	_	PROPN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	stage	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	development	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	true	_	ADJ	_	Degree=Pos	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	12	_	NUM	_	NumType=Card	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
17	stage	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	Stat4	_	PROPN	_	Number=Sing	_	_	_	_
23	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
24	proteins	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	human	_	ADJ	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
9	via	_	ADP	_	_	_	_	_	_
10	IFN	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	able	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
19	Stat4	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	perhaps	_	ADV	_	_	_	_	_	_
4	possible	_	ADJ	_	Degree=Pos	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	all	_	DET	_	_	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Stat4	_	PROPN	_	Number=Sing	_	_	_	_
9	actions	_	NOUN	_	Number=Plur	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	development	_	NOUN	_	Number=Sing	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	exert	_	VERB	_	Degree=Pos	_	_	_	_
16	directly	_	ADV	_	_	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	Stat4	_	PROPN	_	Number=Sing	_	_	_	_
19	at	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IFN	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	gamma	_	NOUN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	however	_	ADV	_	_	_	_	_	_
27	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
28	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	more	_	ADV	_	_	_	_	_	_
32	likely	_	ADJ	_	Degree=Pos	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	Stat4	_	PROPN	_	Number=Sing	_	_	_	_
35	may	_	AUX	_	VerbForm=Fin	_	_	_	_
36	act	_	VERB	_	VerbForm=Inf	_	_	_	_
37	to	_	PART	_	_	_	_	_	_
38	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
39	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	development	_	NOUN	_	Number=Sing	_	_	_	_
41	through	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	induction	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	other	_	ADJ	_	Degree=Pos	_	_	_	_
46	non-cytokine	_	ADJ	_	Degree=Pos	_	_	_	_
47	genes	_	NOUN	_	Number=Plur	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
50	stable	_	ADJ	_	Degree=Pos	_	_	_	_
51	expression	_	NOUN	_	Number=Sing	_	_	_	_
52	maintains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
55	state	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
58	Th1	_	DET	_	Number=Sing	_	_	_	_
59	cell	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003343	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Smad6	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	Smad7	_	PROPN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	bone	_	VERB	_	Number=Sing	_	_	_	_
9	morphogenetic	_	ADJ	_	Degree=Pos	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	activin	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
16	growth	_	NOUN	_	Number=Sing	_	_	_	_
17	arrest	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	B	_	ADJ	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Smad6	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	Smad7	_	PROPN	_	Number=Sing	_	_	_	_
4	prevent	_	VERB	_	Degree=Pos	_	_	_	_
5	ligand	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	transducing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	Smad	_	ADJ	_	Degree=Pos	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
18	growth	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	beta	_	NOUN	_	Number=Sing	_	_	_	_
22	family	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	both	_	CCONJ	_	_	_	_	_	_
6	Smad6	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Smad7	_	PROPN	_	Number=Sing	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	bone	_	NOUN	_	Number=Sing	_	_	_	_
12	morphogenetic	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	hBMP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
23	antagonists	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	hBMP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	growth	_	NOUN	_	Number=Sing	_	_	_	_
31	arrest	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	mouse	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	hybridoma	_	NOUN	_	Number=Sing	_	_	_	_
39	HS	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	72	_	NUM	_	NumType=Card	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	confirmed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
8	expressions	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Smad6	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Smad7	_	PROPN	_	Number=Sing	_	_	_	_
13	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	hBMP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	Smad1	_	PROPN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	Smad5	_	PROPN	_	Number=Sing	_	_	_	_
23	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Smad7	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	activin	_	ADJ	_	Number=Sing	_	_	_	_
9	A	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
12	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	activin	_	ADJ	_	Number=Sing	_	_	_	_
15	A	_	DET	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	growth	_	NOUN	_	Number=Sing	_	_	_	_
19	arrest	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	HS	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	72	_	NUM	_	NumType=Card	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	although	_	SCONJ	_	_	_	_	_	_
4	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Smad6	_	PROPN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	activin	_	NOUN	_	Number=Sing	_	_	_	_
12	A	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	HS	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	72	_	NUM	_	NumType=Card	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	Smad6	_	PROPN	_	Number=Sing	_	_	_	_
20	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	no	_	DET	_	_	_	_	_	_
22	antagonistic	_	ADJ	_	Degree=Pos	_	_	_	_
23	effect	_	NOUN	_	Number=Sing	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	activin	_	ADJ	_	Number=Sing	_	_	_	_
26	A	_	DET	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	growth	_	NOUN	_	Number=Sing	_	_	_	_
30	arrest	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Smad7	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	Smad6	_	PROPN	_	Degree=Pos	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	activin	_	ADJ	_	Number=Sing	_	_	_	_
19	A	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	Smad2	_	PROPN	_	Number=Sing	_	_	_	_
23	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	HS	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	72	_	NUM	_	NumType=Card	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Smad6	_	PROPN	_	Degree=Pos	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Smad7	_	PROPN	_	Degree=Pos	_	_	_	_
6	exhibit	_	NOUN	_	Number=Sing	_	_	_	_
7	differential	_	ADJ	_	Degree=Pos	_	_	_	_
8	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
9	effects	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	bone	_	NOUN	_	Number=Sing	_	_	_	_
12	morphogenetic	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	activin	_	NOUN	_	Number=Sing	_	_	_	_
19	A	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
22	signaling	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	B	_	ADJ	_	Number=Sing	_	_	_	_
25	lineage	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003344	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	interleukin-5	_	NOUN	_	Number=Sing	_	_	_	_
3	/	_	PUNCT	_	_	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	interaction	_	NOUN	_	Number=Sing	_	_	_	_
6	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	Lyn	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	Jak2	_	PROPN	_	Number=Sing	_	_	_	_
10	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
11	kinases	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	propagates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	signals	_	NOUN	_	Number=Plur	_	_	_	_
15	via	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	Ras	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	Raf	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1-	_	NUM	_	_	_	_	_	_
22	MAP	_	NOUN	_	Number=Sing	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	Jak	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	STAT	_	NOUN	_	Number=Sing	_	_	_	_
29	pathways	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	interaction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	-	_	SYM	_	_	_	_	_	_
13	5	_	NUM	_	NumType=Card	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	Lyn	_	PROPN	_	Number=Sing	_	_	_	_
19	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	within	_	ADP	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	min	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	Jak2	_	PROPN	_	Number=Sing	_	_	_	_
26	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
27	kinase	_	NOUN	_	Number=Sing	_	_	_	_
28	within	_	ADP	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	SYM	_	_	_	_	_	_
31	3	_	NUM	_	NumType=Card	_	_	_	_
32	min	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	5	_	NUM	_	NumType=Card	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	GTP	_	PROPN	_	Number=Sing	_	_	_	_
7	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	signal	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	subsequently	_	ADV	_	_	_	_	_	_
5	propagated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	through	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Raf	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	MEK	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	MAP	_	NOUN	_	Number=Sing	_	_	_	_
18	kinases	_	NOUN	_	Number=Plur	_	_	_	_
19	as	_	SCONJ	_	_	_	_	_	_
20	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	autophosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vitro	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	situ	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Jak2	_	PROPN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	phosphorylate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	STAT	_	PROPN	_	Number=Sing	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	STAT	_	PROPN	_	Number=Sing	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
11	mobility	_	NOUN	_	Number=Sing	_	_	_	_
12	shift	_	NOUN	_	Number=Sing	_	_	_	_
13	assay	_	NOUN	_	Number=Sing	_	_	_	_
14	using	_	VERB	_	VerbForm=Ger	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	gamma	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	GAS	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	probe	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	5	_	NUM	_	NumType=Card	_	_	_	_
7	induces	_	VERB	_	Number=Plur	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	GAS	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	one	_	NUM	_	NumType=Card	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Int	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	5	_	NUM	_	NumType=Card	_	_	_	_
7	induced	_	VERB	_	Degree=Pos	_	_	_	_
8	signals	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	propagated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	two	_	NUM	_	NumType=Card	_	_	_	_
13	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
14	pathways	_	NOUN	_	Number=Plur	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	1	_	X	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	Lyn-->Ras	_	NOUN	_	_	_	_	_	_
20	-->	_	PUNCT	_	_	_	_	_	_
21	Raf-1-->MEK	_	PROPN	_	Number=Sing	_	_	_	_
22	-->	_	PUNCT	_	_	_	_	_	_
23	MAP	_	NOUN	_	Number=Sing	_	_	_	_
24	kinase	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	2	_	X	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	Jak2-->STAT1	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003345	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	modulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	myelopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	leukemogenesis	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Acute	_	ADJ	_	Degree=Pos	_	_	_	_
2	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	AML	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	still	_	ADV	_	_	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	mortality	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	60	_	NUM	_	NumType=Card	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	80	_	NUM	_	NumType=Card	_	_	_	_
17	%	_	SYM	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	AML	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	block	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
9	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	C/EB	_	NOUN	_	Number=Sing	_	_	_	_
7	Palpha	_	PROPN	_	Number=Sing	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	normal	_	ADJ	_	Degree=Pos	_	_	_	_
12	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	stem	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	particular	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	PU.	_	PROPN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
11	colony	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	M	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	CSF	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	development	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	whereas	_	SCONJ	_	_	_	_	_	_
28	C	_	PROPN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	EBPalpha	_	PROPN	_	Number=Sing	_	_	_	_
31	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
37	colony	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
40	factor	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	G	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	CSF	_	NOUN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	receptor	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	to	_	ADP	_	_	_	_	_	_
50	mature	_	VERB	_	Degree=Pos	_	_	_	_
51	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	AML	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
5	aberrations	_	NOUN	_	Number=Plur	_	_	_	_
6	result	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	oncoproteins	_	NOUN	_	Number=Plur	_	_	_	_
9	such	_	ADJ	_	Degree=Pos	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	AML1	_	PROPN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	ETO	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	PML	_	PROPN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	RARalpha	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	Ras	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	can	_	AUX	_	VerbForm=Fin	_	_	_	_
25	deregulate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	important	_	ADJ	_	Degree=Pos	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	normal	_	ADJ	_	Degree=Pos	_	_	_	_
30	myelopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	AML1	_	PROPN	_	Number=Sing	_	_	_	_
4	/	_	PUNCT	_	_	_	_	_	_
5	ETO	_	PROPN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	C/EBPalpha	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
15	C/EBPalpha	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	block	_	NOUN	_	Number=Sing	_	_	_	_
22	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	AML1	_	PROPN	_	Number=Sing	_	_	_	_
4	/	_	PUNCT	_	_	_	_	_	_
5	ETO	_	PROPN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	synergize	_	VERB	_	VerbForm=Inf	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	AML1	_	PROPN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	M	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	CSF	_	NOUN	_	Number=Sing	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	hand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	PML	_	PROPN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	RARalpha	_	PROPN	_	Number=Sing	_	_	_	_
10	fusion	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	repression	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	SCONJ	_	_	_	_	_	_
16	recruiting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	corepressor	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	N	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	CoR	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	histone	_	NOUN	_	Number=Sing	_	_	_	_
26	deacetylase	_	NOUN	_	Number=Sing	_	_	_	_
27	complex	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	DNA	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	results	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	histone	_	NOUN	_	Number=Sing	_	_	_	_
37	acetylation	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	repressive	_	ADJ	_	Degree=Pos	_	_	_	_
41	chromatin	_	ADJ	_	Number=Sing	_	_	_	_
42	organization	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	methods	_	NOUN	_	Number=Plur	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	whether	_	SCONJ	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	how	_	ADV	_	PronType=Int	_	_	_	_
10	signaling	_	ADJ	_	Degree=Pos	_	_	_	_
11	agonists	_	NOUN	_	Number=Plur	_	_	_	_
12	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	how	_	ADV	_	PronType=Int	_	_	_	_
17	oncoproteins	_	NOUN	_	Number=Plur	_	_	_	_
18	might	_	AUX	_	VerbForm=Fin	_	_	_	_
19	cause	_	VERB	_	VerbForm=Inf	_	_	_	_
20	AML	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	SCONJ	_	_	_	_	_	_
22	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	factors	_	NOUN	_	Number=Plur	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	pivotal	_	ADJ	_	Degree=Pos	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	normal	_	ADJ	_	Degree=Pos	_	_	_	_
33	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
34	development	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1999	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003348	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	beta	_	NOUN	_	Number=Sing	_	_	_	_
4	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	stromal	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	rescue	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	resolution	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	immune	_	ADJ	_	Number=Sing	_	_	_	_
5	responses	_	NOUN	_	Number=Plur	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	extensive	_	ADJ	_	Degree=Pos	_	_	_	_
10	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	generate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	maintain	_	VERB	_	VerbForm=Inf	_	_	_	_
7	immunological	_	ADJ	_	Degree=Pos	_	_	_	_
8	memory	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	some	_	DET	_	_	_	_	_	_
11	antigen	_	ADJ	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	must	_	AUX	_	VerbForm=Fin	_	_	_	_
17	survive	_	VERB	_	VerbForm=Inf	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	revert	_	VERB	_	VerbForm=Inf	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
23	G0	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	G1	_	NOUN	_	Number=Sing	_	_	_	_
26	state	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Cytokines	_	NOUN	_	Number=Plur	_	_	_	_
2	that	_	PRON	_	PronType=Rel	_	_	_	_
3	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	common	_	ADJ	_	Degree=Pos	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	chain	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	survival	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	blasts	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	also	_	ADV	_	_	_	_	_	_
25	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
26	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	stromal	_	ADJ	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_

1	Tcell	_	PROPN	_	Number=Sing	_	_	_	_
2	survival	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
6	G0	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	G1	_	NOUN	_	Number=Sing	_	_	_	_
9	state	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	interferon	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	principal	_	ADJ	_	Degree=Pos	_	_	_	_
11	mediator	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	stromal	_	ADJ	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
17	Tcell	_	PROPN	_	Number=Sing	_	_	_	_
18	rescue	_	NOUN	_	Number=Sing	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	reversion	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	blast	_	ADJ	_	Degree=Pos	_	_	_	_
12	Tcells	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	G0	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	G1	_	NOUN	_	Number=Sing	_	_	_	_
19	configuration	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	all	_	DET	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	characteristic	_	ADJ	_	Degree=Pos	_	_	_	_
24	features	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	stromal	_	ADJ	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	rescue	_	NOUN	_	Number=Sing	_	_	_	_
29	;	_	PUNCT	_	_	_	_	_	_
30	such	_	ADJ	_	Degree=Pos	_	_	_	_
31	as	_	ADP	_	_	_	_	_	_
32	high	_	ADJ	_	Degree=Pos	_	_	_	_
33	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	XL	_	PROPN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	low	_	ADJ	_	Degree=Pos	_	_	_	_
39	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Type	_	NOUN	_	Number=Sing	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	interferons	_	VERB	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	stromal	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	stimulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	apparently	_	ADV	_	_	_	_	_	_
9	identical	_	ADJ	_	Degree=Pos	_	_	_	_
10	signaling	_	NOUN	_	Number=Sing	_	_	_	_
11	pathways	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	STAT	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	play	_	VERB	_	VerbForm=Inf	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	fundamental	_	ADJ	_	Degree=Pos	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	persistence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	sites	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
22	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
23	;	_	PUNCT	_	_	_	_	_	_
24	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
27	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	aberrant	_	ADJ	_	Degree=Pos	_	_	_	_
31	consequence	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	immunological	_	ADJ	_	Degree=Pos	_	_	_	_
34	memory	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003351	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Effects	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	intranasal	_	ADJ	_	Degree=Pos	_	_	_	_
4	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
7	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
8	peripheral	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	central	_	ADJ	_	Degree=Pos	_	_	_	_
11	function	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	among	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	most	_	ADV	_	_	_	_	_	_
6	potent	_	ADJ	_	Degree=Pos	_	_	_	_
7	antiinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	agents	_	NOUN	_	Number=Plur	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	treatment	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	rhinitis	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	action	_	NOUN	_	Number=Sing	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	complex	_	ADJ	_	Degree=Pos	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	number	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	reports	_	NOUN	_	Number=Plur	_	_	_	_
14	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	significant	_	ADJ	_	Degree=Pos	_	_	_	_
16	systemic	_	ADJ	_	Degree=Pos	_	_	_	_
17	effects	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	locally	_	ADV	_	_	_	_	_	_
20	administered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	evaluate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	short	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	term	_	NOUN	_	Number=Sing	_	_	_	_
9	systemic	_	ADJ	_	Number=Sing	_	_	_	_
10	effects	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	intranasally	_	ADV	_	_	_	_	_	_
13	administered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	14	_	NUM	_	NumType=Card	_	_	_	_
17	normal	_	ADJ	_	Degree=Pos	_	_	_	_
18	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
19	subjects	_	NOUN	_	Number=Plur	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	two	_	NUM	_	NumType=Card	_	_	_	_
24	doses	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	either	_	CCONJ	_	_	_	_	_	_
27	budesonide	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	BUD	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	fluticasone	_	NOUN	_	Number=Sing	_	_	_	_
33	propionate	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	FP	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	weeks	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Before	_	ADP	_	_	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	at	_	ADP	_	_	_	_	_	_
5	regular	_	ADJ	_	Degree=Pos	_	_	_	_
6	intervals	_	NOUN	_	Number=Plur	_	_	_	_
7	during	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	treatment	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	week	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	finally	_	ADV	_	_	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	weeks	_	NOUN	_	Number=Plur	_	_	_	_
17	after	_	ADP	_	_	_	_	_	_
18	termination	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	treatment	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	effects	_	NOUN	_	Number=Plur	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	GR	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	methallothionein	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	MTIIa	_	PROPN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	levels	_	NOUN	_	Number=Plur	_	_	_	_
38	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
39	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
42	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
43	using	_	VERB	_	VerbForm=Ger	_	_	_	_
44	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
45	solution	_	NOUN	_	Number=Sing	_	_	_	_
46	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
47	assay	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Serum	_	ADJ	_	Number=Sing	_	_	_	_
2	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	osteocalcin	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	urinary	_	ADJ	_	Degree=Pos	_	_	_	_
7	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	also	_	ADV	_	_	_	_	_	_
11	determined	_	ADJ	_	Degree=Pos	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	insulin	_	ADJ	_	Number=Sing	_	_	_	_
3	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
4	test	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	ITT	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	end	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
16	week	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	treatment	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	end	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	6	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	week	_	NOUN	_	Number=Sing	_	_	_	_
28	washout	_	NOUN	_	Number=Sing	_	_	_	_
29	period	_	NOUN	_	Number=Sing	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	no	_	DET	_	_	_	_	_	_
32	statistically	_	ADV	_	_	_	_	_	_
33	significant	_	ADJ	_	Degree=Pos	_	_	_	_
34	change	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	cortisol	_	ADJ	_	Degree=Pos	_	_	_	_
37	response	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
3	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	GR	_	NOUN	_	Number=Sing	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	significantly	_	ADV	_	_	_	_	_	_
10	down	_	ADV	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	MTIIa	_	PROPN	_	Number=Sing	_	_	_	_
2	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	significantly	_	ADV	_	_	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	Serum	_	PROPN	_	Number=Sing	_	_	_	_
2	osteocalcin	_	NOUN	_	Number=Sing	_	_	_	_
3	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	significantly	_	ADV	_	_	_	_	_	_
5	during	_	ADP	_	_	_	_	_	_
6	treatment	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	BUD	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	FP	_	PROPN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Serum	_	PROPN	_	Number=Sing	_	_	_	_
2	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
3	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	after	_	ADP	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	week	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	treatment	_	NOUN	_	Number=Sing	_	_	_	_
9	whereas	_	SCONJ	_	_	_	_	_	_
10	urinary	_	ADJ	_	Degree=Pos	_	_	_	_
11	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	until	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
18	week	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	treatment	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	intranasal	_	ADJ	_	Degree=Pos	_	_	_	_
5	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	clinically	_	ADV	_	_	_	_	_	_
8	recommended	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	doses	_	NOUN	_	Number=Plur	_	_	_	_
10	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	ADV	_	_	_	_	_	_
12	only	_	ADV	_	_	_	_	_	_
13	significant	_	ADJ	_	Degree=Pos	_	_	_	_
14	systemic	_	ADJ	_	Degree=Pos	_	_	_	_
15	effects	_	NOUN	_	Number=Plur	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	adrenal	_	ADJ	_	Degree=Pos	_	_	_	_
18	function	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	also	_	ADV	_	_	_	_	_	_
22	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	effect	_	NOUN	_	Number=Sing	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
31	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	reversible	_	ADJ	_	Degree=Pos	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	according	_	VERB	_	VerbForm=Ger	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	serum	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	urinary	_	ADJ	_	Degree=Pos	_	_	_	_
16	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
17	levels	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	ITT	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	leave	_	VERB	_	VerbForm=Inf	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	hypothalamic	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	adrenal	_	ADJ	_	Degree=Pos	_	_	_	_
28	function	_	NOUN	_	Number=Sing	_	_	_	_
29	intact	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	short	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	term	_	NOUN	_	Number=Sing	_	_	_	_
7	systemic	_	NOUN	_	Number=Sing	_	_	_	_
8	effects	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	any	_	DET	_	_	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	noticeable	_	ADJ	_	Degree=Pos	_	_	_	_
17	side	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	effects	_	NOUN	_	Number=Plur	_	_	_	_
20	usually	_	ADV	_	_	_	_	_	_
21	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	during	_	ADP	_	_	_	_	_	_
23	long	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	term	_	NOUN	_	Number=Sing	_	_	_	_
26	treatment	_	NOUN	_	Number=Sing	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003354	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Association	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	chain	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	p47phox	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	activator	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	phagocyte	_	NOUN	_	Number=Sing	_	_	_	_
18	NADPH	_	PROPN	_	Number=Sing	_	_	_	_
19	oxidase	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	B	_	ADJ	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	IgE	_	PROPN	_	Number=Sing	_	_	_	_
13	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	B	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	Th2	_	DET	_	Degree=Pos	_	_	_	_
20	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	conducts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
6	biological	_	ADJ	_	Degree=Pos	_	_	_	_
7	activities	_	NOUN	_	Number=Plur	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	4R	_	NUM	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	surface	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	target	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4R	_	PROPN	_	Number=Sing	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4R	_	PROPN	_	Number=Sing	_	_	_	_
14	alpha	_	PROPN	_	Number=Sing	_	_	_	_
15	chain	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	4R	_	PROPN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	either	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2R	_	NOUN	_	Number=Sing	_	_	_	_
28	gamma	_	NOUN	_	Number=Sing	_	_	_	_
29	chain	_	NOUN	_	Number=Sing	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	13R	_	NOUN	_	Number=Sing	_	_	_	_
35	alpha	_	PROPN	_	Number=Sing	_	_	_	_
36	chain	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	membrane	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
10	portion	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
14	domain	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	4R	_	PROPN	_	Number=Sing	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	hIL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	4R	_	NOUN	_	Number=Sing	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	critical	_	ADJ	_	Degree=Pos	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	generation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	germline	_	NOUN	_	Number=Sing	_	_	_	_
36	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
37	transcript	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	on	_	ADP	_	_	_	_	_	_
46	analyses	_	NOUN	_	Number=Plur	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	truncated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
49	hIL	_	NOUN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	4R	_	NOUN	_	Number=Sing	_	_	_	_
52	alphas	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	p47phox	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	activator	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	phagocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	NADPH	_	PROPN	_	Number=Sing	_	_	_	_
16	oxidase	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	portion	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	two	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
27	system	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	association	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	p47phox	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	hIL	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4R	_	NOUN	_	Number=Sing	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	normal	_	ADJ	_	Degree=Pos	_	_	_	_
22	donor	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	p47phox	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	involved	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	signal	_	ADJ	_	Number=Sing	_	_	_	_
11	transduction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	CD23	_	PROPN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	IgE	_	PROPN	_	Number=Sing	_	_	_	_
12	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	4	_	NUM	_	NumType=Card	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	p47phox	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
25	patients	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	raises	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	possibility	_	NOUN	_	Number=Sing	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	p47phox	_	NOUN	_	Number=Sing	_	_	_	_
33	may	_	AUX	_	VerbForm=Fin	_	_	_	_
34	be	_	AUX	_	VerbForm=Inf	_	_	_	_
35	important	_	ADJ	_	Degree=Pos	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	other	_	ADJ	_	Degree=Pos	_	_	_	_
38	signaling	_	NOUN	_	Number=Sing	_	_	_	_
39	activities	_	NOUN	_	Number=Plur	_	_	_	_
40	as	_	ADV	_	_	_	_	_	_
41	well	_	ADV	_	Degree=Pos	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	B	_	ADJ	_	Degree=Pos	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003355	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	Spi	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	regulate	_	VERB	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
17	colony	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Growth	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	receptors	_	NOUN	_	Number=Plur	_	_	_	_
4	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	important	_	ADJ	_	Degree=Pos	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	further	_	ADV	_	_	_	_	_	_
5	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	directing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	key	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulators	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	initiated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	study	_	NOUN	_	Number=Sing	_	_	_	_
22	investigating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factors	_	NOUN	_	Number=Plur	_	_	_	_
26	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
34	colony	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
37	factor	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	GM	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	CSF	_	PROPN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	receptor	_	NOUN	_	Number=Sing	_	_	_	_
44	alpha	_	NOUN	_	Number=Sing	_	_	_	_
45	gene	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	GM	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CSF	_	PROPN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	directs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	reporter	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	tissue	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	fashion	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	pattern	_	NOUN	_	Number=Sing	_	_	_	_
34	as	_	SCONJ	_	_	_	_	_	_
35	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	reverse	_	NOUN	_	Number=Sing	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	PCR	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GM	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	CSF	_	PROPN	_	Number=Sing	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	functional	_	ADJ	_	Degree=Pos	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	between	_	ADP	_	_	_	_	_	_
14	positions	_	NOUN	_	Number=Plur	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	53	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	-	_	SYM	_	_	_	_	_	_
19	41	_	NUM	_	NumType=Card	_	_	_	_
20	as	_	SCONJ	_	_	_	_	_	_
21	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	deletion	_	NOUN	_	Number=Sing	_	_	_	_
24	analysis	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	reporter	_	NOUN	_	Number=Sing	_	_	_	_
27	constructs	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
12	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	specifically	_	ADV	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	CCAAT	_	ADJ	_	Number=Sing	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	upstream	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	between	_	ADP	_	_	_	_	_	_
16	positions	_	NOUN	_	Number=Plur	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	70	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	-	_	SYM	_	_	_	_	_	_
21	54	_	NUM	_	NumType=Card	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	involved	_	ADJ	_	Degree=Pos	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	positive	_	ADJ	_	Degree=Pos	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	negative	_	ADJ	_	Degree=Pos	_	_	_	_
28	regulation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	GM	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	CSF	_	NOUN	_	Number=Sing	_	_	_	_
34	receptor	_	NOUN	_	Number=Sing	_	_	_	_
35	alpha	_	NOUN	_	Number=Sing	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	activity	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
2	alpha	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	major	_	ADJ	_	Degree=Pos	_	_	_	_
6	CCAAT	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	C	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	EBP	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	form	_	NOUN	_	Number=Sing	_	_	_	_
18	binding	_	VERB	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	extracts	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	U937	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Point	_	NOUN	_	Number=Sing	_	_	_	_
2	mutations	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	either	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	abolish	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	respective	_	ADJ	_	Degree=Pos	_	_	_	_
19	factors	_	NOUN	_	Number=Plur	_	_	_	_
20	result	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	significant	_	ADJ	_	Degree=Pos	_	_	_	_
24	decrease	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	GM	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	CSF	_	NOUN	_	Number=Sing	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	promoter	_	NOUN	_	Number=Sing	_	_	_	_
32	activity	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	only	_	ADV	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	extracts	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	PU.	_	NOUN	_	Number=Sing	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	forms	_	NOUN	_	Number=Plur	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	novel	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	more	_	ADV	_	_	_	_	_	_
22	slowly	_	ADV	_	_	_	_	_	_
23	migrating	_	VERB	_	VerbForm=Ger	_	_	_	_
24	complex	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	PU	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	SF	_	PROPN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	when	_	ADV	_	PronType=Int	_	_	_	_
31	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	GM	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	CSF	_	PROPN	_	Number=Sing	_	_	_	_
36	receptor	_	NOUN	_	Number=Sing	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	promoter	_	NOUN	_	Number=Sing	_	_	_	_
39	PU.	_	NOUN	_	Number=Sing	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	site	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
5	demonstration	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	interaction	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	myeloid	_	PROPN	_	Number=Sing	_	_	_	_
15	PU.	_	NOUN	_	Number=Sing	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	complex	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
8	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	previously	_	ADV	_	_	_	_	_	_
10	as	_	SCONJ	_	_	_	_	_	_
11	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	B	_	NOUN	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	can	_	AUX	_	VerbForm=Fin	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	formed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	addition	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	extracts	_	NOUN	_	Number=Plur	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	certain	_	ADJ	_	Degree=Pos	_	_	_	_
29	nonmyeloid	_	ADJ	_	Degree=Pos	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	types	_	NOUN	_	Number=Plur	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	express	_	VERB	_	VerbForm=Inf	_	_	_	_
36	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	including	_	VERB	_	VerbForm=Ger	_	_	_	_
39	T	_	NOUN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	but	_	CCONJ	_	_	_	_	_	_
46	not	_	ADV	_	_	_	_	_	_
47	from	_	ADP	_	_	_	_	_	_
48	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
49	cells	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	PU	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	SF	_	PROPN	_	Number=Sing	_	_	_	_
10	complex	_	ADJ	_	Number=Sing	_	_	_	_
11	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	PU.	_	NOUN	_	Number=Sing	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	sites	_	NOUN	_	Number=Plur	_	_	_	_
16	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	number	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
22	promoters	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	formation	_	NOUN	_	Number=Sing	_	_	_	_
27	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	intact	_	ADJ	_	Degree=Pos	_	_	_	_
30	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	adjacent	_	VERB	_	Number=Sing	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	single	_	ADJ	_	Degree=Pos	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	stranded	_	VERB	_	Degree=Pos	_	_	_	_
38	region	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	nonmyeloid	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	GM	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	CSF	_	NOUN	_	Number=Sing	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	amino	_	ADJ	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	terminal	_	NOUN	_	Number=Sing	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	PU.	_	NOUN	_	Number=Sing	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	results	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	failure	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	form	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	PU	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	SF	_	PROPN	_	Number=Sing	_	_	_	_
21	complex	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
26	loss	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	formation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	PU	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	SF	_	PROPN	_	Number=Sing	_	_	_	_
38	complex	_	NOUN	_	Number=Sing	_	_	_	_
39	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	functional	_	ADJ	_	Degree=Pos	_	_	_	_
42	importance	_	NOUN	_	Number=Sing	_	_	_	_
43	for	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	activity	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	GM	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	CSF	_	PROPN	_	Number=Sing	_	_	_	_
51	receptor	_	NOUN	_	Number=Sing	_	_	_	_
52	alpha	_	NOUN	_	Number=Sing	_	_	_	_
53	promoter	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	active	_	VERB	_	VerbForm=Inf	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	GM	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	CSF	_	PROPN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	nonmyeloid	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	400	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	003003358	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	tepoxalin	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	surface	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
17	molecules	_	NOUN	_	Number=Plur	_	_	_	_
18	CD62E	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	CD11b	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	CD18	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	CD106	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Tepoxalin	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	dual	_	ADJ	_	Degree=Pos	_	_	_	_
5	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
6	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	cyclooxygenase	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	5	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	lipoxygenase	_	NOUN	_	Number=Sing	_	_	_	_
13	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
15	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
18	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
3	property	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
8	because	_	SCONJ	_	_	_	_	_	_
9	only	_	ADV	_	_	_	_	_	_
10	tepoxalin	_	ADJ	_	Degree=Pos	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	cyclosporin	_	ADJ	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	tepoxalin	_	NOUN	_	Number=Sing	_	_	_	_
6	selectively	_	ADV	_	_	_	_	_	_
7	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
9	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
10	molecule	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	CD54	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	MAC	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	CD11b	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	CD18	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
30	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	polymorphonuclear	_	ADJ	_	Degree=Pos	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	human	_	ADJ	_	Degree=Pos	_	_	_	_
40	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
41	vein	_	NOUN	_	Number=Sing	_	_	_	_
42	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	related	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	surface	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	several	_	ADJ	_	Degree=Pos	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
15	molecules	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Flow	_	VERB	_	Number=Sing	_	_	_	_
2	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
3	analyses	_	NOUN	_	Number=Plur	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	cultured	_	VERB	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	tepoxalin	_	NOUN	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	antisense	_	ADJ	_	Degree=Pos	_	_	_	_
14	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	P65	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	p50	_	NOUN	_	Number=Sing	_	_	_	_
20	subunit	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	then	_	ADV	_	PronType=Dem	_	_	_	_
29	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	PMA	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	CD11b	_	NOUN	_	Number=Sing	_	_	_	_
39	/	_	PUNCT	_	_	_	_	_	_
40	CD18	_	NOUN	_	Number=Sing	_	_	_	_
41	on	_	ADP	_	_	_	_	_	_
42	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
43	HL60	_	PROPN	_	Number=Sing	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
48	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
49	molecule	_	NOUN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	1	_	NUM	_	NumType=Card	_	_	_	_
52	(	_	PUNCT	_	_	_	_	_	_
53	CD62E	_	NOUN	_	Number=Sing	_	_	_	_
54	)	_	PUNCT	_	_	_	_	_	_
55	and	_	CCONJ	_	_	_	_	_	_
56	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
57	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
58	molecule	_	NOUN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	1	_	NUM	_	NumType=Card	_	_	_	_
61	(	_	PUNCT	_	_	_	_	_	_
62	CD106	_	NOUN	_	Number=Sing	_	_	_	_
63	)	_	PUNCT	_	_	_	_	_	_
64	on	_	ADP	_	_	_	_	_	_
65	human	_	ADJ	_	Degree=Pos	_	_	_	_
66	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
67	vein	_	NOUN	_	Number=Sing	_	_	_	_
68	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
69	cells	_	NOUN	_	Number=Plur	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
5	molecules	_	NOUN	_	Number=Plur	_	_	_	_
6	such	_	ADJ	_	Degree=Pos	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
9	function	_	NOUN	_	Number=Sing	_	_	_	_
10	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	antigen	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	CD11a	_	PROPN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	CD18	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	CD54	_	PROPN	_	Number=Sing	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Tepoxalin	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	secretion	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	8	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	known	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
21	inducer	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	CD18	_	PROPN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	suppression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	CD18	_	PROPN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	tepoxalin	_	NOUN	_	Number=Sing	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	8	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	by	_	SCONJ	_	_	_	_	_	_
6	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	surface	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	several	_	ADJ	_	Degree=Pos	_	_	_	_
17	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
18	molecules	_	NOUN	_	Number=Plur	_	_	_	_
19	can	_	AUX	_	VerbForm=Fin	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	tepoxalin	_	NOUN	_	Number=Sing	_	_	_	_
25	may	_	AUX	_	VerbForm=Fin	_	_	_	_
26	be	_	AUX	_	VerbForm=Inf	_	_	_	_
27	useful	_	ADJ	_	Degree=Pos	_	_	_	_
28	in	_	SCONJ	_	_	_	_	_	_
29	treating	_	VERB	_	VerbForm=Ger	_	_	_	_
30	selected	_	VERB	_	Degree=Pos	_	_	_	_
31	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
32	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	events	_	NOUN	_	Number=Plur	_	_	_	_
34	such	_	ADJ	_	Degree=Pos	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
37	migration	_	NOUN	_	Number=Sing	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	atherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
40	plaque	_	NOUN	_	Number=Sing	_	_	_	_
41	formation	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003360	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Chronic	_	ADJ	_	Degree=Pos	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	infection	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	disrupts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	control	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	Rel	_	NOUN	_	Number=Sing	_	_	_	_
22	pathway	_	NOUN	_	Number=Sing	_	_	_	_
23	via	_	ADP	_	_	_	_	_	_
24	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
26	degradation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Productive	_	ADJ	_	Degree=Pos	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	infection	_	NOUN	_	Number=Sing	_	_	_	_
13	causes	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	ADJ	_	Number=Sing	_	_	_	_
18	DNA	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	chronically	_	ADV	_	_	_	_	_	_
24	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	direct	_	ADJ	_	Degree=Pos	_	_	_	_
3	temporal	_	ADJ	_	Degree=Pos	_	_	_	_
4	correlation	_	NOUN	_	Number=Sing	_	_	_	_
5	exists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	infection	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	appearance	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	binding	_	VERB	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	myelomonoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
22	PLB	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	985	_	NUM	_	NumType=Card	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	basis	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	DNA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	HIV1	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
22	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	turnover	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	activity	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	double	_	ADJ	_	Degree=Pos	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	RNA	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
41	protein	_	NOUN	_	Number=Sing	_	_	_	_
42	kinase	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	PKR	_	PROPN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
49	levels	_	NOUN	_	Number=Plur	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	NF	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
54	subunits	_	NOUN	_	Number=Plur	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	PLB	_	NOUN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	985	_	NUM	_	NumType=Card	_	_	_	_
60	and	_	CCONJ	_	_	_	_	_	_
61	U937	_	NOUN	_	Number=Sing	_	_	_	_
62	myeloid	_	NOUN	_	NumType=Card	_	_	_	_
63	cell	_	NOUN	_	Number=Sing	_	_	_	_
64	models	_	NOUN	_	Number=Plur	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	infection	_	NOUN	_	Number=Sing	_	_	_	_
5	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	low	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	level	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	type	_	NOUN	_	Number=Sing	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	interferon	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	IFN	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
23	level	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	PKR	_	NOUN	_	Number=Sing	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	result	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	low	_	ADJ	_	Degree=Pos	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	IFN	_	NOUN	_	Number=Sing	_	_	_	_
22	production	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	since	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	addition	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	anti-IFN	_	ADJ	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	beta	_	NOUN	_	Number=Sing	_	_	_	_
33	antibody	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	PKR	_	PROPN	_	Number=Sing	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
7	turnover	_	NOUN	_	Number=Sing	_	_	_	_
8	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	degradation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	HIV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	may	_	AUX	_	VerbForm=Fin	_	_	_	_
23	account	_	VERB	_	VerbForm=Inf	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
27	DNA	_	NOUN	_	Number=Sing	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
3	increase	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	subunits	_	NOUN	_	Number=Plur	_	_	_	_
13	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB2	_	VERB	_	Number=Sing	_	_	_	_
18	p100	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	moderate	_	ADJ	_	Degree=Pos	_	_	_	_
22	increase	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB2	_	NOUN	_	Number=Sing	_	_	_	_
27	p52	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	RelA	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	p65	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	HIV	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	whereas	_	SCONJ	_	_	_	_	_	_
44	NF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	kappaB1	_	NOUN	_	Number=Sing	_	_	_	_
47	p105	_	NOUN	_	Number=Sing	_	_	_	_
48	/	_	PUNCT	_	_	_	_	_	_
49	p50	_	NUM	_	Number=Sing	_	_	_	_
50	levels	_	NOUN	_	Number=Plur	_	_	_	_
51	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
52	not	_	PART	_	_	_	_	_	_
53	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
54	relative	_	ADV	_	_	_	_	_	_
55	to	_	ADP	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	levels	_	NOUN	_	Number=Plur	_	_	_	_
58	in	_	ADP	_	_	_	_	_	_
59	uninfected	_	ADJ	_	Degree=Pos	_	_	_	_
60	cells	_	NOUN	_	Number=Plur	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	infection	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	IFN	_	PROPN	_	Number=Sing	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	PKR	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	turn	_	NOUN	_	Number=Sing	_	_	_	_
21	contribute	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
25	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
28	degradation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	translocation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	subunits	_	NOUN	_	Number=Plur	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	ultimately	_	ADV	_	_	_	_	_	_
10	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
13	pool	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	turnover	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	Rel	_	NOUN	_	Number=Sing	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	chronically	_	ADV	_	_	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	state	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	HIV	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003364	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	gamma	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	delta	_	PROPN	_	Number=Sing	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	positive	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	pregnancy	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	PROBLEM	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	Due	_	ADP	_	_	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	lack	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	classical	_	ADJ	_	Degree=Pos	_	_	_	_
7	HLA	_	PROPN	_	Number=Sing	_	_	_	_
8	antigens	_	NOUN	_	Number=Plur	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	trophoblast	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	fetal	_	NOUN	_	Number=Sing	_	_	_	_
14	antigens	_	NOUN	_	Number=Plur	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	possibly	_	ADV	_	_	_	_	_	_
17	presented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	non	_	X	_	_	_	_	_	_
21	major	_	ADJ	_	Degree=Pos	_	_	_	_
22	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	MHC	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	way	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Decidual	_	ADJ	_	Degree=Pos	_	_	_	_
2	gammadelta	_	NOUN	_	Number=Sing	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	significantly	_	ADV	_	_	_	_	_	_
8	increase	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	number	_	NOUN	_	Number=Sing	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	pregnancy	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	might	_	AUX	_	VerbForm=Fin	_	_	_	_
15	play	_	VERB	_	VerbForm=Inf	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	recognition	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	fetal	_	ADJ	_	Degree=Pos	_	_	_	_
22	antigens	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	also	_	ADV	_	_	_	_	_	_
25	in	_	SCONJ	_	_	_	_	_	_
26	determining	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	quality	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	response	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
34	antigens	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	aimed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	at	_	SCONJ	_	_	_	_	_	_
6	investigating	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	population	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	immunomodulation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	METHOD	_	NOUN	_	Number=Sing	_	_	_	_
2	OF	_	ADP	_	_	_	_	_	_
3	STUDY	_	PROPN	_	Number=Sing	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_

1	Peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
5	pregnant	_	ADJ	_	Degree=Pos	_	_	_	_
6	women	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	habitual	_	ADJ	_	Degree=Pos	_	_	_	_
10	aborters	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	tested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	immunocytochemistry	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	presence	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	gamma	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	delta	_	PROPN	_	Number=Sing	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	TCR	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
30	receptor	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	treatment	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	pan	_	NOUN	_	Number=Sing	_	_	_	_
10	anti	_	X	_	_	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	delta	_	NOUN	_	Number=Sing	_	_	_	_
14	antibody	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	incubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	hr	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	antibody	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	then	_	ADV	_	PronType=Dem	_	_	_	_
28	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	10	_	NUM	_	NumType=Card	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	12	_	NUM	_	NumType=Card	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	blocking	_	NOUN	_	Number=Sing	_	_	_	_
43	factor	_	NOUN	_	Number=Sing	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	PIBF	_	NOUN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	by	_	ADP	_	_	_	_	_	_
50	immuno	_	ADJ	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	cytochemistry	_	NOUN	_	Number=Sing	_	_	_	_
53	)	_	PUNCT	_	_	_	_	_	_
54	as	_	ADV	_	_	_	_	_	_
55	well	_	ADV	_	Degree=Pos	_	_	_	_
56	as	_	ADP	_	_	_	_	_	_
57	natural	_	ADJ	_	Degree=Pos	_	_	_	_
58	killer	_	NOUN	_	Number=Sing	_	_	_	_
59	(	_	PUNCT	_	_	_	_	_	_
60	NK	_	PROPN	_	Number=Sing	_	_	_	_
61	)	_	PUNCT	_	_	_	_	_	_
62	cell	_	NOUN	_	Number=Sing	_	_	_	_
63	activity	_	NOUN	_	Number=Sing	_	_	_	_
64	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
65	determined	_	ADJ	_	Degree=Pos	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
3	blood	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
6	pregnant	_	ADJ	_	Degree=Pos	_	_	_	_
7	women	_	NOUN	_	Number=Plur	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	percentage	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	delta	_	NOUN	_	Number=Sing	_	_	_	_
14	TCR	_	NOUN	_	Number=Sing	_	_	_	_
15	+	_	SYM	_	_	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	significantly	_	ADV	_	_	_	_	_	_
19	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	P	_	NOUN	_	Number=Sing	_	_	_	_
22	<	_	PUNCT	_	_	_	_	_	_
23	0.001	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	than	_	ADP	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	recurrent	_	ADJ	_	Degree=Pos	_	_	_	_
30	aborters	_	NOUN	_	Number=Plur	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	non-pregnant	_	ADJ	_	Degree=Pos	_	_	_	_
34	individuals	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Ninety	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	seven	_	NUM	_	NumType=Card	_	_	_	_
4	percent	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	gamma	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	delta	_	NOUN	_	Number=Sing	_	_	_	_
9	TCR	_	NOUN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_
11	pregnancy	_	NOUN	_	Number=Sing	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	antibody	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	delta	_	PROPN	_	Number=Sing	_	_	_	_
11	TCR	_	NOUN	_	Number=Sing	_	_	_	_
12	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	PIBF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	as	_	ADV	_	_	_	_	_	_
16	well	_	ADV	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	10	_	NUM	_	NumType=Card	_	_	_	_
21	production	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	whereas	_	SCONJ	_	_	_	_	_	_
24	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
25	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	NK	_	PROPN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	12	_	NUM	_	NumType=Card	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	delta	_	NOUN	_	Number=Sing	_	_	_	_
10	TCR	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	immunomodulation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003368	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	functional	_	ADJ	_	Degree=Pos	_	_	_	_
3	synergy	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	12	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	p38	_	NUM	_	Number=Sing	_	_	_	_
14	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	kinase	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	augmentation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	STAT	_	PROPN	_	Number=Sing	_	_	_	_
27	serine	_	NOUN	_	Number=Sing	_	_	_	_
28	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	12	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	CD3	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	proliferate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
22	IFN	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	gamma	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	kill	_	VERB	_	VerbForm=Inf	_	_	_	_
28	tumor	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	functional	_	ADJ	_	Degree=Pos	_	_	_	_
6	responses	_	NOUN	_	Number=Plur	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	greatly	_	ADV	_	_	_	_	_	_
9	augmented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	when	_	ADV	_	PronType=Int	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	combination	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	12	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
3	blood	_	NOUN	_	Number=Sing	_	_	_	_
4	T	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	largely	_	ADV	_	_	_	_	_	_
8	unresponsive	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
12	without	_	ADP	_	_	_	_	_	_
13	prior	_	ADJ	_	Degree=Pos	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	small	_	ADJ	_	Degree=Pos	_	_	_	_
18	subset	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	CD8	_	NOUN	_	Number=Sing	_	_	_	_
21	+	_	SYM	_	_	_	_	_	_

1	T	_	NUM	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	CD8	_	NOUN	_	Number=Sing	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_
6	CD18bright	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	strongly	_	ADV	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	combination	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	12	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	functional	_	ADJ	_	Degree=Pos	_	_	_	_
9	synergy	_	NOUN	_	Number=Sing	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	12	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	CD8	_	PROPN	_	Number=Sing	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_
21	CD18bright	_	PROPN	_	Number=Sing	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	stress	_	NOUN	_	Number=Sing	_	_	_	_
31	kinases	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	p38	_	NOUN	_	Number=Sing	_	_	_	_
34	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	protein	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	MAP	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	kinase	_	NOUN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	stress	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	protein	_	NOUN	_	Number=Sing	_	_	_	_
47	kinase	_	NOUN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	SAPK	_	PROPN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	/	_	PUNCT	_	_	_	_	_	_
52	Jun	_	PROPN	_	Number=Sing	_	_	_	_
53	N	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
56	kinase	_	NOUN	_	Number=Sing	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	but	_	CCONJ	_	_	_	_	_	_
59	not	_	ADV	_	_	_	_	_	_
60	with	_	ADP	_	_	_	_	_	_
61	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
62	activation	_	NOUN	_	Number=Sing	_	_	_	_
63	of	_	ADP	_	_	_	_	_	_
64	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
65	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
66	signal	_	NOUN	_	Number=Sing	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
69	kinases	_	NOUN	_	Number=Plur	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	functional	_	ADJ	_	Degree=Pos	_	_	_	_
3	synergy	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	12	_	NUM	_	NumType=Card	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	prominent	_	ADJ	_	Degree=Pos	_	_	_	_
18	increase	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
23	serine	_	NOUN	_	Number=Sing	_	_	_	_
24	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
25	over	_	ADP	_	_	_	_	_	_
26	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
27	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	12	_	NUM	_	NumType=Card	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	alone	_	ADJ	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	STAT	_	NOUN	_	Number=Sing	_	_	_	_
5	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	augmented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	over	_	ADP	_	_	_	_	_	_
11	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
12	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	either	_	CCONJ	_	_	_	_	_	_
15	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
16	alone	_	ADV	_	_	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	specific	_	ADJ	_	Degree=Pos	_	_	_	_
3	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	p38	_	NOUN	_	Number=Sing	_	_	_	_
6	MAP	_	NOUN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	completely	_	ADV	_	_	_	_	_	_
9	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	serine	_	NOUN	_	Number=Sing	_	_	_	_
12	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	12	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	abrogates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	functional	_	ADJ	_	Degree=Pos	_	_	_	_
30	synergy	_	NOUN	_	Number=Sing	_	_	_	_
31	between	_	ADP	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	12	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	without	_	SCONJ	_	_	_	_	_	_
40	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
41	STAT	_	NOUN	_	Number=Sing	_	_	_	_
42	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
43	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	p38	_	NOUN	_	Number=Sing	_	_	_	_
5	MAP	_	NOUN	_	Number=Sing	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	play	_	VERB	_	VerbForm=Inf	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	SCONJ	_	_	_	_	_	_
13	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	STAT	_	PROPN	_	Number=Sing	_	_	_	_
15	serine	_	NOUN	_	Number=Sing	_	_	_	_
16	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	combination	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	12	_	NUM	_	NumType=Card	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	findings	_	NOUN	_	Number=Plur	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	12	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	may	_	AUX	_	VerbForm=Fin	_	_	_	_
22	depend	_	VERB	_	VerbForm=Inf	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	interaction	_	NOUN	_	Number=Sing	_	_	_	_
26	between	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	p38	_	NOUN	_	Number=Sing	_	_	_	_
29	MAP	_	NOUN	_	Number=Sing	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	Janus	_	PROPN	_	Number=Sing	_	_	_	_
33	kinase	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	STAT	_	PROPN	_	Number=Sing	_	_	_	_
36	signaling	_	NOUN	_	Number=Sing	_	_	_	_
37	pathways	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003369	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	6	_	NUM	_	NumType=Card	_	_	_	_
4	production	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	hemorrhagic	_	ADJ	_	Number=Sing	_	_	_	_
7	shock	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
12	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	lung	_	NOUN	_	Number=Sing	_	_	_	_
15	injury	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Hemorrhagic	_	PROPN	_	Number=Sing	_	_	_	_
2	shock	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	HS	_	X	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	initiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	cascade	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	PMN	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	may	_	AUX	_	VerbForm=Fin	_	_	_	_
25	progress	_	VERB	_	VerbForm=Inf	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	organ	_	ADJ	_	Degree=Pos	_	_	_	_
28	failure	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
31	acute	_	ADJ	_	Degree=Pos	_	_	_	_
32	respiratory	_	ADJ	_	Degree=Pos	_	_	_	_
33	distress	_	NOUN	_	Number=Sing	_	_	_	_
34	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	ARDS	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	SCONJ	_	PronType=Rel	_	_	_	_
6	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	6	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	PMN	_	PROPN	_	Number=Sing	_	_	_	_
17	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	lung	_	NOUN	_	Number=Sing	_	_	_	_
20	damage	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	HS	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
25	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	lungs	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	rats	_	NOUN	_	Number=Plur	_	_	_	_
30	subjected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	unresuscitated	_	ADJ	_	Degree=Pos	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	resuscitated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	HS	_	PROPN	_	Number=Sing	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	production	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	6	_	NUM	_	NumType=Card	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	activation	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	semiquantitative	_	ADJ	_	Degree=Pos	_	_	_	_
3	RT	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	PCR	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	striking	_	NOUN	_	VerbForm=Ger	_	_	_	_
11	increase	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
17	levels	_	NOUN	_	Number=Plur	_	_	_	_
18	only	_	ADV	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	resuscitated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	HS	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	peak	_	NOUN	_	Number=Sing	_	_	_	_
25	levels	_	NOUN	_	Number=Plur	_	_	_	_
26	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	h	_	NOUN	_	Number=Sing	_	_	_	_
29	after	_	ADP	_	_	_	_	_	_
30	initiation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	resuscitation	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	6	_	NUM	_	NumType=Card	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	bronchial	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	extracts	_	NOUN	_	Number=Plur	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	shock	_	NOUN	_	Number=Sing	_	_	_	_
10	lungs	_	NOUN	_	Number=Plur	_	_	_	_
11	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	increase	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
19	similar	_	ADJ	_	Degree=Pos	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	6	_	NUM	_	NumType=Card	_	_	_	_
24	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	situ	_	NOUN	_	Number=Sing	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
5	assay	_	ADV	_	Number=Sing	_	_	_	_
6	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	predominantly	_	ADV	_	_	_	_	_	_
10	within	_	ADP	_	_	_	_	_	_
11	alveoli	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Intratracheal	_	ADJ	_	Number=Sing	_	_	_	_
2	instillation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	alone	_	ADV	_	_	_	_	_	_
8	into	_	ADP	_	_	_	_	_	_
9	normal	_	ADJ	_	Degree=Pos	_	_	_	_
10	rats	_	NOUN	_	Number=Plur	_	_	_	_
11	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	PMN	_	PROPN	_	Number=Sing	_	_	_	_
14	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
15	into	_	ADP	_	_	_	_	_	_
16	lung	_	NOUN	_	Number=Sing	_	_	_	_
17	interstitium	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	alveoli	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	elevation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	bronchoalveolar	_	NOUN	_	Number=Sing	_	_	_	_
25	lavage	_	NOUN	_	Number=Sing	_	_	_	_
26	cellularity	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	wet	_	ADJ	_	Degree=Pos	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	dry	_	NOUN	_	Degree=Pos	_	_	_	_
35	ratio	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	6	_	NUM	_	NumType=Card	_	_	_	_
8	production	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	occur	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	early	_	ADV	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	HS	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	PMN	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	lung	_	NOUN	_	Number=Sing	_	_	_	_
24	injury	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	including	_	VERB	_	VerbForm=Ger	_	_	_	_
27	ARDS	_	NOUN	_	Number=Sing	_	_	_	_
28	after	_	ADP	_	_	_	_	_	_
29	HS	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003371	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	B	_	PROPN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
8	potentiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
13	promoters	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	octamer	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factors	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	high	_	ADJ	_	Degree=Pos	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	octamer	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	Oct	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
23	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
24	chain	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	IgH	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
31	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	vitro	_	NOUN	_	Number=Sing	_	_	_	_
36	system	_	NOUN	_	Number=Sing	_	_	_	_
37	consisting	_	VERB	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	extracts	_	NOUN	_	Number=Plur	_	_	_	_
44	complemented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	with	_	ADP	_	_	_	_	_	_
46	fractionated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	B	_	NOUN	_	Number=Sing	_	_	_	_
48	cell	_	NOUN	_	Number=Sing	_	_	_	_
49	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
50	proteins	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	designated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	Oct	_	PROPN	_	Number=Sing	_	_	_	_
10	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	B	_	ADJ	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	OCA	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	OCA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	B	_	PROPN	_	Number=Sing	_	_	_	_
4	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	IgH	_	NOUN	_	Degree=Pos	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	conjunction	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	either	_	CCONJ	_	_	_	_	_	_
15	Oct	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	Oct	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	SYM	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	no	_	DET	_	_	_	_	_	_
25	significant	_	ADJ	_	Degree=Pos	_	_	_	_
26	effect	_	NOUN	_	Number=Sing	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	octamer	_	NOUN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	Oct	_	X	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	ubiquitously	_	ADV	_	_	_	_	_	_
38	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	histone	_	NOUN	_	Number=Sing	_	_	_	_
40	H2B	_	NOUN	_	Number=Sing	_	_	_	_
41	promoter	_	NOUN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	transcription	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	USF	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
52	promoters	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	OCA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	tissue	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	that	_	DET	_	_	_	_	_	_
26	OCA	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	B	_	PROPN	_	Number=Sing	_	_	_	_
29	may	_	AUX	_	VerbForm=Fin	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	major	_	ADJ	_	Degree=Pos	_	_	_	_
33	determinant	_	NOUN	_	Number=Sing	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	B	_	ADJ	_	Degree=Pos	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	specific	_	ADJ	_	Degree=Pos	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
42	promoters	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	light	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	evidence	_	NOUN	_	Number=Sing	_	_	_	_
6	showing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	physical	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	functional	_	ADJ	_	Degree=Pos	_	_	_	_
10	interactions	_	NOUN	_	Number=Plur	_	_	_	_
11	between	_	ADP	_	_	_	_	_	_
12	Oct	_	X	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	OCA	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	action	_	NOUN	_	Number=Sing	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	OCA	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	B	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	discuss	_	VERB	_	VerbForm=Inf	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	implications	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	OCA	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	B	_	X	_	Number=Sing	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
40	regulation	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	other	_	ADJ	_	Degree=Pos	_	_	_	_
43	tissue	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	specific	_	ADJ	_	Degree=Pos	_	_	_	_
46	promoters	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003373	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Heterogeneity	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	antigen	_	ADJ	_	Number=Sing	_	_	_	_
4	molecules	_	NOUN	_	Number=Plur	_	_	_	_
5	recognized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	anti-tax1	_	ADJ	_	Degree=Pos	_	_	_	_
8	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
9	antibody	_	NOUN	_	Number=Sing	_	_	_	_
10	Lt	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	lines	_	NOUN	_	Number=Plur	_	_	_	_
16	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
21	virus	_	NOUN	_	Number=Sing	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	related	_	VERB	_	Degree=Pos	_	_	_	_
26	retroviruses	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
4	antibody	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	Lt	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	against	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	trans	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	activator	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	tax1	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	antigen	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
33	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	tax1	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	related	_	ADJ	_	Degree=Pos	_	_	_	_
40	antigens	_	NOUN	_	Number=Plur	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	variety	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	T	_	NOUN	_	Number=Sing	_	_	_	_
46	cell	_	NOUN	_	Number=Sing	_	_	_	_
47	lines	_	NOUN	_	Number=Plur	_	_	_	_
48	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
49	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	related	_	ADJ	_	Degree=Pos	_	_	_	_
54	retroviruses	_	NOUN	_	Number=Plur	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	simian	_	ADJ	_	Degree=Pos	_	_	_	_
57	T	_	NOUN	_	Number=Sing	_	_	_	_
58	cell	_	NOUN	_	Number=Sing	_	_	_	_
59	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
60	virus	_	NOUN	_	Number=Sing	_	_	_	_
61	type	_	NOUN	_	Number=Sing	_	_	_	_
62	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
63	(	_	PUNCT	_	_	_	_	_	_
64	STLV	_	PROPN	_	Number=Sing	_	_	_	_
65	-	_	PUNCT	_	_	_	_	_	_
66	I	_	NUM	_	NumType=Card	_	_	_	_
67	)	_	PUNCT	_	_	_	_	_	_
68	and	_	CCONJ	_	_	_	_	_	_
69	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	II	_	NUM	_	NumType=Card	_	_	_	_
72	,	_	PUNCT	_	_	_	_	_	_
73	by	_	ADP	_	_	_	_	_	_
74	immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
75	and	_	CCONJ	_	_	_	_	_	_
76	immunoblot	_	ADJ	_	Number=Sing	_	_	_	_
77	assays	_	NOUN	_	Number=Plur	_	_	_	_
78	.	_	PUNCT	_	_	_	_	_	_

1	Lt	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	reacted	_	VERB	_	Degree=Pos	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	all	_	DET	_	_	_	_	_	_
7	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	lines	_	NOUN	_	Number=Plur	_	_	_	_
14	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	five	_	NUM	_	NumType=Card	_	_	_	_
17	out	_	ADP	_	_	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	eight	_	NUM	_	NumType=Card	_	_	_	_
20	simian	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	lines	_	NOUN	_	Number=Plur	_	_	_	_
23	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	STLV	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	but	_	CCONJ	_	_	_	_	_	_
29	not	_	ADV	_	_	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	II	_	NUM	_	NumType=Card	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	bearing	_	NOUN	_	VerbForm=Ger	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	line	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Lt	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	40	_	NUM	_	NumType=Card	_	_	_	_
6	kd	_	NOUN	_	Number=Sing	_	_	_	_
7	tax1	_	NOUN	_	Number=Sing	_	_	_	_
8	antigen	_	ADJ	_	Number=Sing	_	_	_	_
9	molecules	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	most	_	ADJ	_	Degree=Sup	_	_	_	_
12	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lines	_	NOUN	_	Number=Plur	_	_	_	_
19	except	_	ADP	_	_	_	_	_	_
20	one	_	NUM	_	NumType=Card	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	line	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	39	_	NUM	_	NumType=Card	_	_	_	_
26	kd	_	NOUN	_	Number=Sing	_	_	_	_
27	tax1	_	NOUN	_	Number=Sing	_	_	_	_
28	antigen	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	STLV	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	I-bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	tax1	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	related	_	ADJ	_	Degree=Pos	_	_	_	_
13	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
14	molecules	_	NOUN	_	Number=Plur	_	_	_	_
15	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	Lt	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	4	_	NUM	_	NumType=Card	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	heterogeneous	_	ADJ	_	Degree=Pos	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	having	_	VERB	_	VerbForm=Ger	_	_	_	_
24	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
25	weights	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	range	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	36	_	NUM	_	NumType=Card	_	_	_	_
31	-	_	SYM	_	_	_	_	_	_
32	41	_	NUM	_	NumType=Card	_	_	_	_
33	kd	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003375	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cutting	_	NOUN	_	VerbForm=Ger	_	_	_	_
2	edge	_	NOUN	_	Number=Sing	_	_	_	_
3	:	_	PUNCT	_	_	_	_	_	_

1	TCR	_	NOUN	_	Number=Sing	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	antibody	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
7	superantigen	_	NOUN	_	Number=Sing	_	_	_	_
8	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TCR	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	CD3	_	PROPN	_	Number=Sing	_	_	_	_
8	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
9	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	murine	_	NOUN	_	Number=Sing	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	CD3	_	PROPN	_	Number=Sing	_	_	_	_
7	ligation	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	mAb	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	Staphylococcal	_	PROPN	_	Number=Sing	_	_	_	_
12	enterotoxin	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	SE	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	gradually	_	ADV	_	_	_	_	_	_
21	accumulating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	long	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	lasting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	serine	_	NOUN	_	Number=Sing	_	_	_	_
30	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	not	_	ADV	_	_	_	_	_	_
36	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	allogen	_	ADJ	_	NumType=Card	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	specific	_	ADJ	_	Degree=Pos	_	_	_	_
42	human	_	ADJ	_	Degree=Pos	_	_	_	_
43	CD4	_	NOUN	_	Number=Sing	_	_	_	_
44	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	transient	_	ADJ	_	Degree=Pos	_	_	_	_
12	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	serine	_	NOUN	_	Number=Sing	_	_	_	_
15	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	CD3	_	PROPN	_	Number=Sing	_	_	_	_
8	ligation	_	NOUN	_	Number=Sing	_	_	_	_
9	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
12	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	oligonucleotide	_	ADJ	_	VerbForm=Inf	_	_	_	_
16	probes	_	NOUN	_	Number=Plur	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2R	_	PROPN	_	Number=Sing	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	CD3	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	almost	_	ADV	_	_	_	_	_	_
9	completely	_	ADV	_	_	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	Src	_	PROPN	_	Number=Sing	_	_	_	_
14	kinase	_	NOUN	_	Number=Sing	_	_	_	_
15	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	PP1	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	whereas	_	SCONJ	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	CD3	_	PROPN	_	Number=Sing	_	_	_	_
8	ligation	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	mAb	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	SE	_	PROPN	_	Number=Sing	_	_	_	_
13	triggers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	PP1	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
20	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	serine	_	NOUN	_	Number=Sing	_	_	_	_
23	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	CD4	_	NOUN	_	Number=Sing	_	_	_	_
29	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	evidence	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	TCR	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	CD3	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	induce	_	VERB	_	Number=Sing	_	_	_	_
15	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	via	_	ADP	_	_	_	_	_	_
18	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
19	signaling	_	VERB	_	Number=Sing	_	_	_	_
20	pathways	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003378	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Anti-immunoglobulin	_	PROPN	_	Degree=Pos	_	_	_	_
2	M	_	PROPN	_	Number=Sing	_	_	_	_
3	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	calcium	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	calmodulin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	II	_	NUM	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	others	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	previously	_	ADV	_	_	_	_	_	_
6	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	Ets	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	calcium	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	manner	_	NOUN	_	Number=Sing	_	_	_	_
24	after	_	ADP	_	_	_	_	_	_
25	ligation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	immunoglobulin	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	Ig	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	M	_	NOUN	_	Number=Sing	_	_	_	_
32	on	_	ADP	_	_	_	_	_	_
33	B	_	NOUN	_	Degree=Pos	_	_	_	_
34	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	independent	_	ADJ	_	Degree=Pos	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	C	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	whether	_	SCONJ	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	calcium	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	calmodulin	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	kinase	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	CaM	_	PROPN	_	Number=Sing	_	_	_	_
25	kinase	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	might	_	AUX	_	VerbForm=Fin	_	_	_	_
28	phosphorylate	_	VERB	_	VerbForm=Inf	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	Ets	_	NOUN	_	Number=Plur	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	protein	_	NOUN	_	Number=Sing	_	_	_	_
34	after	_	ADP	_	_	_	_	_	_
35	elevation	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
38	free	_	ADJ	_	Degree=Pos	_	_	_	_
39	calcium	_	NOUN	_	Number=Sing	_	_	_	_
40	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	dephosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
3	form	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Ets	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	operative	_	ADJ	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	should	_	AUX	_	VerbForm=Fin	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	prepared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	extracts	_	NOUN	_	Number=Plur	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	lines	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	free	_	ADJ	_	Degree=Pos	_	_	_	_
16	calcium	_	NOUN	_	Number=Sing	_	_	_	_
17	levels	_	NOUN	_	Number=Plur	_	_	_	_
18	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	Ets	_	NOUN	_	Number=Plur	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Activity	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CaM	_	PROPN	_	Number=Sing	_	_	_	_
5	kinases	_	NOUN	_	Number=Plur	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	using	_	VERB	_	VerbForm=Ger	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
11	peptide	_	NOUN	_	Number=Sing	_	_	_	_
12	substrate	_	NOUN	_	Number=Sing	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	absence	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	presence	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	CaM	_	PROPN	_	Number=Sing	_	_	_	_
26	kinase	_	NOUN	_	Number=Sing	_	_	_	_
27	family	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	KN	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	62	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	anti-IgM	_	NOUN	_	Number=Sing	_	_	_	_
6	led	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	could	_	AUX	_	VerbForm=Fin	_	_	_	_
16	phosphorylate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	peptide	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	10	_	NUM	_	NumType=Card	_	_	_	_
27	microM	_	NOUN	_	Number=Sing	_	_	_	_
28	KN	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	SYM	_	_	_	_	_	_
30	62	_	NUM	_	NumType=Card	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Kinase	_	PROPN	_	Number=Sing	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	lysates	_	NOUN	_	Number=Plur	_	_	_	_
7	preadsorbed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	using	_	VERB	_	VerbForm=Ger	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	antibody	_	NOUN	_	Number=Sing	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	CaM	_	PROPN	_	Number=Sing	_	_	_	_
14	kinase	_	NOUN	_	Number=Sing	_	_	_	_
15	II	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dimensional	_	ADJ	_	Degree=Pos	_	_	_	_
4	phosphopeptide	_	NOUN	_	Number=Sing	_	_	_	_
5	maps	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	Ets	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	incubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	anti-IgM	_	NOUN	_	Number=Sing	_	_	_	_
19	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	two	_	NUM	_	NumType=Card	_	_	_	_
21	unique	_	ADJ	_	Degree=Pos	_	_	_	_
22	phosphopeptides	_	NOUN	_	Number=Plur	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	absent	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Incubation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	Ets	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	CaM	_	PROPN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	II	_	NUM	_	NumType=Card	_	_	_	_
13	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	peptides	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	migrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	identically	_	ADV	_	_	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
22	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	incubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	either	_	CCONJ	_	_	_	_	_	_
28	anti-IgM	_	NOUN	_	Number=Sing	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	model	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	signal	_	NOUN	_	Number=Sing	_	_	_	_
8	transduction	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	antigen	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
20	free	_	ADJ	_	Degree=Pos	_	_	_	_
21	calcium	_	NOUN	_	Number=Sing	_	_	_	_
22	can	_	AUX	_	VerbForm=Fin	_	_	_	_
23	rapidly	_	ADV	_	_	_	_	_	_
24	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
25	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	CaM	_	PROPN	_	Number=Sing	_	_	_	_
27	kinase	_	NOUN	_	Number=Sing	_	_	_	_
28	II	_	NUM	_	NumType=Card	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	potentially	_	ADV	_	_	_	_	_	_
31	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	regulation	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	DNA	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	binding	_	VERB	_	Number=Sing	_	_	_	_
40	proteins	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003384	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	balance	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
7	production	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	transducer	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	activator	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	STAT	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
26	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
27	fluids	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	balance	_	NOUN	_	Number=Sing	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	helper	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	important	_	ADJ	_	Degree=Pos	_	_	_	_
16	role	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	several	_	ADJ	_	Degree=Pos	_	_	_	_
19	animal	_	NOUN	_	Number=Sing	_	_	_	_
20	models	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	autoimmunity	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	skewed	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
26	patterns	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
32	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	human	_	ADJ	_	Degree=Pos	_	_	_	_
35	inflammatory	_	ADJ	_	Number=Sing	_	_	_	_
36	diseases	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Many	_	ADJ	_	Degree=Pos	_	_	_	_
2	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
3	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	signal	_	NOUN	_	Number=Sing	_	_	_	_
5	transducer	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	STAT	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	turn	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	activate	_	ADJ	_	Degree=Pos	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	effector	_	NOUN	_	Number=Sing	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	priming	_	NOUN	_	VerbForm=Ger	_	_	_	_
6	cultures	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
10	fluids	_	NOUN	_	Number=Plur	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	SFs	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
17	patients	_	NOUN	_	Number=Plur	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	regulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
24	production	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	STAT	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
32	microenvironment	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Exposure	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	SFs	_	NOUN	_	Number=Sing	_	_	_	_
4	during	_	ADP	_	_	_	_	_	_
5	priming	_	NOUN	_	Number=Sing	_	_	_	_
6	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	81	_	NUM	_	NumType=Card	_	_	_	_
10	%	_	SYM	_	Number=Sing	_	_	_	_
11	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	interferon	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	IFN	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	gamma	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	not	_	ADV	_	_	_	_	_	_
22	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	4	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	production	_	NOUN	_	Number=Sing	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	effector	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	priming	_	ADJ	_	VerbForm=Ger	_	_	_	_
35	cultures	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	SF	_	PROPN	_	Number=Sing	_	_	_	_
2	suppression	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	10	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	12	_	NUM	_	NumType=Card	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	reversed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
28	fashion	_	NOUN	_	Number=Sing	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	12	_	NUM	_	NumType=Card	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	SFs	_	PROPN	_	Number=Sing	_	_	_	_
2	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	ADV	_	_	_	_	_	_
13	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	during	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	priming	_	NOUN	_	Number=Sing	_	_	_	_
18	period	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	differentially	_	ADV	_	_	_	_	_	_
25	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	parallel	_	NOUN	_	Number=Sing	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
32	positive	_	ADJ	_	Degree=Pos	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	negative	_	ADJ	_	Degree=Pos	_	_	_	_
35	regulation	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	IFN	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	gamma	_	NOUN	_	Number=Sing	_	_	_	_
40	production	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Active	_	ADJ	_	Degree=Pos	_	_	_	_
2	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	but	_	CCONJ	_	_	_	_	_	_
5	not	_	ADV	_	_	_	_	_	_
6	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	inflamed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	joints	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	altered	_	VERB	_	Degree=Pos	_	_	_	_
8	balance	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	synovitis	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003386	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CD40	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	but	_	CCONJ	_	_	_	_	_	_
4	not	_	ADV	_	_	_	_	_	_
5	lipopolysaccharide	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	anti-IgM	_	ADJ	_	Degree=Pos	_	_	_	_
8	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	primary	_	ADJ	_	Degree=Pos	_	_	_	_
11	B	_	NOUN	_	Degree=Pos	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	RelB	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	CD40	_	PROPN	_	Number=Sing	_	_	_	_
10	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	appearance	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	Rel	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	primary	_	ADJ	_	Degree=Pos	_	_	_	_
31	murine	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	triggering	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CD40	_	PROPN	_	Number=Sing	_	_	_	_
7	signaling	_	VERB	_	Number=Sing	_	_	_	_
8	pathway	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	s	_	X	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	CD40	_	PROPN	_	Number=Sing	_	_	_	_
14	ligands	_	NOUN	_	Number=Plur	_	_	_	_
15	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	L	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	led	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	strong	_	ADJ	_	Degree=Pos	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	beta-globin	_	NOUN	_	Number=Sing	_	_	_	_
31	reporter	_	NOUN	_	Number=Sing	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	primary	_	ADJ	_	Degree=Pos	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	from	_	ADP	_	_	_	_	_	_
38	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
39	mice	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Analyses	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	translocation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	individual	_	ADJ	_	Degree=Pos	_	_	_	_
7	members	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Rel	_	NOUN	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	after	_	ADP	_	_	_	_	_	_
12	CD40	_	PROPN	_	Number=Sing	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	primary	_	ADJ	_	Degree=Pos	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	strong	_	ADJ	_	Degree=Pos	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	long	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	lasting	_	VERB	_	Degree=Pos	_	_	_	_
25	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	RelB	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	less	_	ADV	_	Degree=Cmp	_	_	_	_
31	pronounced	_	ADJ	_	Degree=Pos	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	PROPN	_	Number=Sing	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	give	_	VERB	_	VerbForm=Inf	_	_	_	_
6	rise	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	RelB	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	whereas	_	ADV	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	not	_	ADV	_	_	_	_	_	_
23	RelB	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	accumulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	after	_	ADP	_	_	_	_	_	_
27	B	_	NOUN	_	Degree=Pos	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	CD40	_	PROPN	_	Number=Sing	_	_	_	_
2	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	not	_	ADV	_	_	_	_	_	_
4	only	_	ADV	_	_	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	translocation	_	NOUN	_	Number=Sing	_	_	_	_
7	but	_	CCONJ	_	_	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	de	_	VERB	_	Number=Sing	_	_	_	_
10	novo	_	X	_	Number=Sing	_	_	_	_
11	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	RelB	_	PROPN	_	Number=Sing	_	_	_	_
14	RNA	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	S107	_	NUM	_	Number=Sing	_	_	_	_
2	plasmacytoma	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	CD40	_	PROPN	_	Number=Sing	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	defective	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	appearance	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	p50/p65	_	NUM	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	express	_	VERB	_	VerbForm=Inf	_	_	_	_
25	RelB	_	NOUN	_	Number=Sing	_	_	_	_
26	after	_	ADP	_	_	_	_	_	_
27	CD40	_	PROPN	_	Number=Sing	_	_	_	_
28	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	S107	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	stably	_	ADV	_	_	_	_	_	_
5	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	relB	_	ADJ	_	Degree=Pos	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	RelB	_	NOUN	_	Number=Sing	_	_	_	_
14	translocation	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	CD40	_	PROPN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CD40	_	NOUN	_	Number=Sing	_	_	_	_
8	signaling	_	VERB	_	Number=Sing	_	_	_	_
9	pathways	_	NOUN	_	Number=Plur	_	_	_	_
10	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	long	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	lasting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	effect	_	NOUN	_	Number=Sing	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	translocation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	RelB	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	LPS	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	anti-IgM	_	NOUN	_	Number=Sing	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	unable	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	RelB	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	CD40	_	PROPN	_	Number=Sing	_	_	_	_
12	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	trigger	_	VERB	_	VerbForm=Inf	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	special	_	ADJ	_	Degree=Pos	_	_	_	_
17	program	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	involved	_	ADJ	_	Degree=Pos	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	B	_	NOUN	_	Degree=Pos	_	_	_	_
31	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003387	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Temperature	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	down	_	ADP	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
13	blood	_	NOUN	_	Number=Sing	_	_	_	_
14	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	leucocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	patients	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	septic	_	ADJ	_	Number=Sing	_	_	_	_
22	shock	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	OBJECTIVE	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	hypothalamic	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	adrenal	_	ADJ	_	Degree=Pos	_	_	_	_
11	axis	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	vital	_	ADJ	_	Degree=Pos	_	_	_	_
15	importance	_	NOUN	_	Number=Sing	_	_	_	_
16	during	_	ADP	_	_	_	_	_	_
17	critical	_	ADJ	_	Degree=Pos	_	_	_	_
18	illness	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	adaptive	_	ADJ	_	Degree=Pos	_	_	_	_
6	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	occur	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	level	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
18	target	_	NOUN	_	Number=Sing	_	_	_	_
19	tissues	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	patients	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	septic	_	ADJ	_	Number=Sing	_	_	_	_
26	shock	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	DESIGN	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	hypercortisolaemia	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	hyperthermia	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	composition	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	number	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
16	receptors	_	NOUN	_	Number=Plur	_	_	_	_
17	per	_	ADP	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	affinity	_	NOUN	_	Number=Sing	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	both	_	CCONJ	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	vitro	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	vivo	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
34	blood	_	NOUN	_	Number=Sing	_	_	_	_
35	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
36	leucocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	control	_	NOUN	_	Number=Sing	_	_	_	_
39	subjects	_	NOUN	_	Number=Plur	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	patients	_	NOUN	_	Number=Sing	_	_	_	_
43	with	_	ADP	_	_	_	_	_	_
44	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
45	or	_	CCONJ	_	_	_	_	_	_
46	septic	_	ADJ	_	Number=Sing	_	_	_	_
47	shock	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	SUBJECTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	Fifteen	_	NUM	_	NumType=Card	_	_	_	_
2	patients	_	NOUN	_	Number=Plur	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	age	_	NOUN	_	Number=Sing	_	_	_	_
5	25	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	SYM	_	_	_	_	_	_
7	79	_	NUM	_	NumType=Card	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	septic	_	ADJ	_	Number=Sing	_	_	_	_
13	shock	_	NOUN	_	Number=Sing	_	_	_	_
14	who	_	PRON	_	PronType=Rel	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	admitted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	intensive	_	ADJ	_	Degree=Pos	_	_	_	_
20	care	_	NOUN	_	Number=Sing	_	_	_	_
21	unit	_	NOUN	_	Number=Sing	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	control	_	NOUN	_	Number=Sing	_	_	_	_
3	group	_	NOUN	_	Number=Sing	_	_	_	_
4	consisted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	24	_	NUM	_	NumType=Card	_	_	_	_
7	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
8	laboratory	_	NOUN	_	Number=Sing	_	_	_	_
9	employees	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	MEASUREMENTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	capacity	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	affinity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
9	receptors	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
16	data	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	plasma	_	NOUN	_	Number=Sing	_	_	_	_
20	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
21	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Hypercortisolaemia	_	X	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	vitro	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	affinity	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	capacity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	hyperthermia	_	NOUN	_	Number=Sing	_	_	_	_
5	as	_	ADV	_	_	_	_	_	_
6	well	_	ADV	_	Degree=Pos	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	variations	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
12	composition	_	NOUN	_	Number=Sing	_	_	_	_
13	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	there	_	PRON	_	_	_	_	_	_
5	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	no	_	DET	_	_	_	_	_	_
7	change	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	number	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	receptors	_	NOUN	_	Number=Plur	_	_	_	_
13	per	_	ADP	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	patients	_	NOUN	_	Number=Plur	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	septic	_	ADJ	_	Number=Sing	_	_	_	_
21	shock	_	NOUN	_	Number=Sing	_	_	_	_
22	as	_	SCONJ	_	_	_	_	_	_
23	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
26	controls	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	affinity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	weak	_	ADJ	_	Degree=Pos	_	_	_	_
5	but	_	CCONJ	_	_	_	_	_	_
6	significant	_	ADJ	_	Degree=Pos	_	_	_	_
7	negative	_	ADJ	_	Degree=Pos	_	_	_	_
8	correlation	_	NOUN	_	Number=Sing	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	body	_	NOUN	_	Number=Sing	_	_	_	_
11	temperature	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	number	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
17	receptors	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	patient	_	NOUN	_	Number=Sing	_	_	_	_
21	group	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	relation	_	NOUN	_	Number=Sing	_	_	_	_
5	between	_	ADP	_	_	_	_	_	_
6	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
7	cortisol	_	ADJ	_	Number=Sing	_	_	_	_
8	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	affinity	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	number	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	obvious	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	number	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
11	receptors	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	plasma	_	NOUN	_	Number=Sing	_	_	_	_
14	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
15	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	vivo	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	affinity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	together	_	ADV	_	_	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	negative	_	ADJ	_	Degree=Pos	_	_	_	_
12	correlation	_	NOUN	_	Number=Sing	_	_	_	_
13	between	_	ADP	_	_	_	_	_	_
14	hyperthermia	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	number	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
20	receptors	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	patients	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	septic	_	ADJ	_	Degree=Pos	_	_	_	_
27	shock	_	NOUN	_	Number=Sing	_	_	_	_
28	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	hypothalamic	_	ADJ	_	Degree=Pos	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	adrenal	_	ADJ	_	Degree=Pos	_	_	_	_
35	axis	_	NOUN	_	Number=Sing	_	_	_	_
36	activation	_	NOUN	_	Number=Sing	_	_	_	_
37	during	_	ADP	_	_	_	_	_	_
38	critical	_	ADJ	_	Degree=Pos	_	_	_	_
39	illness	_	NOUN	_	Number=Sing	_	_	_	_
40	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
42	by	_	ADP	_	_	_	_	_	_
43	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
44	adaptation	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
47	receptor	_	NOUN	_	Number=Sing	_	_	_	_
48	number	_	NOUN	_	Number=Sing	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	affinity	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003388	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
2	peptidoglycan	_	ADJ	_	Number=Sing	_	_	_	_
3	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	CD14	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	CREB	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	ATF	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1.	_	NUM	_	NumType=Card	_	_	_	_
18	Peptidoglycan	_	PROPN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	PGN	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	major	_	ADJ	_	Degree=Pos	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	wall	_	NOUN	_	Number=Sing	_	_	_	_
27	component	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	Gram	_	ADJ	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	positive	_	ADJ	_	Degree=Pos	_	_	_	_
32	bacteria	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	secretion	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
40	through	_	ADP	_	_	_	_	_	_
41	CD14	_	PROPN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	pattern	_	NOUN	_	Number=Sing	_	_	_	_
45	recognition	_	NOUN	_	Number=Sing	_	_	_	_
46	receptor	_	NOUN	_	Number=Sing	_	_	_	_
47	that	_	PRON	_	PronType=Rel	_	_	_	_
48	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	other	_	ADJ	_	Degree=Pos	_	_	_	_
52	microbial	_	ADJ	_	Degree=Pos	_	_	_	_
53	products	_	NOUN	_	Number=Plur	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	begin	_	VERB	_	VerbForm=Inf	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	elucidate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	wanted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
19	which	_	DET	_	PronType=Int	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	PGN	_	PROPN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	mouse	_	NOUN	_	Number=Sing	_	_	_	_
28	RAW264.7	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	THP	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	:	_	PUNCT	_	_	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	i	_	X	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	PGN	_	PROPN	_	Number=Sing	_	_	_	_
10	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	ATF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	CREB	_	PROPN	_	Number=Sing	_	_	_	_
21	;	_	PUNCT	_	_	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	ii	_	X	_	_	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	ATF	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	CREB	_	NOUN	_	Number=Sing	_	_	_	_
30	bound	_	ADJ	_	Degree=Pos	_	_	_	_
31	DNA	_	NOUN	_	Number=Sing	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	dimer	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
38	activation	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	CRE	_	NOUN	_	Number=Sing	_	_	_	_
42	reporter	_	NOUN	_	Number=Sing	_	_	_	_
43	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	which	_	PRON	_	PronType=Rel	_	_	_	_
46	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
47	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	by	_	ADP	_	_	_	_	_	_
49	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
50	negative	_	ADJ	_	Degree=Pos	_	_	_	_
51	CREB	_	NOUN	_	Number=Sing	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	ATF	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	1	_	NUM	_	NumType=Card	_	_	_	_
56	;	_	PUNCT	_	_	_	_	_	_
57	(	_	PUNCT	_	_	_	_	_	_
58	iii	_	X	_	_	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	PGN	_	PROPN	_	Number=Sing	_	_	_	_
61	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
62	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
63	of	_	ADP	_	_	_	_	_	_
64	c	_	NOUN	_	Number=Sing	_	_	_	_
65	-	_	PUNCT	_	_	_	_	_	_
66	Jun	_	PROPN	_	Number=Sing	_	_	_	_
67	,	_	PUNCT	_	_	_	_	_	_
68	protein	_	NOUN	_	Number=Sing	_	_	_	_
69	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
70	of	_	ADP	_	_	_	_	_	_
71	JunB	_	PROPN	_	Number=Sing	_	_	_	_
72	and	_	CCONJ	_	_	_	_	_	_
73	c-Fos	_	NOUN	_	Number=Sing	_	_	_	_
74	,	_	PUNCT	_	_	_	_	_	_
75	and	_	CCONJ	_	_	_	_	_	_
76	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
77	activation	_	NOUN	_	Number=Sing	_	_	_	_
78	of	_	ADP	_	_	_	_	_	_
79	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
80	AP	_	NOUN	_	Number=Sing	_	_	_	_
81	-	_	PUNCT	_	_	_	_	_	_
82	1	_	NUM	_	NumType=Card	_	_	_	_
83	reporter	_	NOUN	_	Number=Sing	_	_	_	_
84	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
85	,	_	PUNCT	_	_	_	_	_	_
86	which	_	PRON	_	PronType=Rel	_	_	_	_
87	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
88	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
89	by	_	ADP	_	_	_	_	_	_
90	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
91	negative	_	ADJ	_	Degree=Pos	_	_	_	_
92	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
93	;	_	PUNCT	_	_	_	_	_	_
94	and	_	CCONJ	_	_	_	_	_	_
95	(	_	PUNCT	_	_	_	_	_	_
96	iv	_	X	_	_	_	_	_	_
97	)	_	PUNCT	_	_	_	_	_	_
98	PGN	_	PROPN	_	Number=Sing	_	_	_	_
99	-	_	PUNCT	_	_	_	_	_	_
100	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
101	activation	_	NOUN	_	Number=Sing	_	_	_	_
102	of	_	ADP	_	_	_	_	_	_
103	CREB	_	PROPN	_	Number=Sing	_	_	_	_
104	/	_	PUNCT	_	_	_	_	_	_
105	ATF	_	PROPN	_	Number=Sing	_	_	_	_
106	and	_	CCONJ	_	_	_	_	_	_
107	AP	_	NOUN	_	Number=Sing	_	_	_	_
108	-	_	PUNCT	_	_	_	_	_	_
109	1	_	NUM	_	NumType=Card	_	_	_	_
110	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
111	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
112	through	_	ADP	_	_	_	_	_	_
113	CD14	_	PROPN	_	Number=Sing	_	_	_	_
114	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	demonstrate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	CREB	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	ATF	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	PGN	_	PROPN	_	Number=Sing	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	any	_	DET	_	_	_	_	_	_
24	other	_	ADJ	_	Degree=Pos	_	_	_	_
25	component	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	Gram	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	positive	_	ADJ	_	Degree=Pos	_	_	_	_
30	bacteria	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003389	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nonradioactive	_	ADJ	_	Degree=Pos	_	_	_	_
2	quantification	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	during	_	ADP	_	_	_	_	_	_
8	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	U937	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	method	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	relative	_	ADJ	_	Degree=Pos	_	_	_	_
7	quantification	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	using	_	VERB	_	VerbForm=Ger	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	nonradioactive	_	ADJ	_	Degree=Pos	_	_	_	_
14	assay	_	NOUN	_	Number=Sing	_	_	_	_
15	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	DNA	_	NOUN	_	Number=Sing	_	_	_	_
18	strand	_	NOUN	_	Number=Sing	_	_	_	_
19	competition	_	NOUN	_	Number=Sing	_	_	_	_
20	between	_	ADP	_	_	_	_	_	_
21	identical	_	ADJ	_	Degree=Pos	_	_	_	_
22	sequences	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	biotin	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	fluorescein	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	labeled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	amplicon	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	probe	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	unlabeled	_	ADJ	_	Degree=Pos	_	_	_	_
36	amplicon	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	target	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	during	_	ADP	_	_	_	_	_	_
41	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	target	_	NOUN	_	Number=Sing	_	_	_	_
4	quantity	_	NOUN	_	Number=Sing	_	_	_	_
5	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	double	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	labeled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	probe	_	NOUN	_	Number=Sing	_	_	_	_
14	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	accordance	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	mass	_	ADJ	_	Degree=Pos	_	_	_	_
20	action	_	NOUN	_	Number=Sing	_	_	_	_
21	law	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	technique	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	successfully	_	ADV	_	_	_	_	_	_
5	applied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	evaluate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	differences	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	U937	_	NUM	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	before	_	ADV	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	after	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	addition	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	potent	_	ADJ	_	Degree=Pos	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	inducers	_	NOUN	_	Number=Plur	_	_	_	_
25	:	_	PUNCT	_	_	_	_	_	_

1	12	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	O-tetradecanoylphorbol	_	NOUN	_	Number=Sing	_	_	_	_
4	13	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	acetate	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	TPA	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	combination	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	all	_	DET	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	trans	_	NOUN	_	Number=Plur	_	_	_	_
17	retinoic	_	PROPN	_	Number=Sing	_	_	_	_
18	acid	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	RA	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	1,25	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
26	D2	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	VD	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	TPA	_	PROPN	_	Number=Sing	_	_	_	_
5	treatment	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	increase	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	[	_	PUNCT	_	_	_	_	_	_
16	3H	_	NUM	_	Number=Sing	_	_	_	_
17	]	_	PUNCT	_	_	_	_	_	_
18	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	up	_	ADP	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	regulation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	GR	_	NOUN	_	Number=Sing	_	_	_	_
25	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
26	while	_	SCONJ	_	_	_	_	_	_
27	no	_	DET	_	_	_	_	_	_
28	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	GR	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
32	perceived	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	RA	_	NOUN	_	Number=Sing	_	_	_	_
35	/	_	PUNCT	_	_	_	_	_	_
36	VD	_	NOUN	_	Number=Sing	_	_	_	_
37	treatment	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003390	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Alternative	_	ADJ	_	Degree=Pos	_	_	_	_
2	polyadenylation	_	NOUN	_	Number=Sing	_	_	_	_
3	events	_	NOUN	_	Number=Plur	_	_	_	_
4	contribute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	ATc	_	PROPN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	effector	_	NOUN	_	Number=Sing	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	ATc	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	synthesized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	three	_	NUM	_	NumType=Card	_	_	_	_
11	prominent	_	ADJ	_	Degree=Pos	_	_	_	_
12	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	differ	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	length	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
8	C	_	NOUN	_	Number=Sing	_	_	_	_
9	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
10	peptides	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	mode	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Due	_	ADP	_	_	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	switch	_	NOUN	_	Number=Sing	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	use	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	'	_	PUNCT	_	_	_	_	_	_
12	polyA	_	NOUN	_	Number=Sing	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	more	_	ADV	_	_	_	_	_	_
17	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
18	polyA	_	NOUN	_	Number=Sing	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	ATc	_	PROPN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	switches	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	two	_	NUM	_	NumType=Card	_	_	_	_
32	longer	_	ADJ	_	Degree=Cmp	_	_	_	_
33	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	naive	_	ADJ	_	Degree=Pos	_	_	_	_
36	T	_	PROPN	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	short	_	ADJ	_	Degree=Pos	_	_	_	_
42	isoform	_	NOUN	_	Number=Sing	_	_	_	_
43	A	_	NOUN	_	Definite=Ind|PronType=Art	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	T	_	NOUN	_	Number=Sing	_	_	_	_
46	effector	_	NOUN	_	Number=Sing	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	relative	_	ADJ	_	Degree=Pos	_	_	_	_
3	low	_	ADJ	_	Degree=Pos	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	affinity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
8	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	CstF	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	64	_	NUM	_	NumType=Card	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
16	polyA	_	NOUN	_	Number=Sing	_	_	_	_
17	site	_	NOUN	_	Number=Sing	_	_	_	_
18	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	neglect	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	naive	_	ADJ	_	Degree=Pos	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
3	polyadenylation	_	NOUN	_	Number=Sing	_	_	_	_
4	events	_	NOUN	_	Number=Plur	_	_	_	_
5	ensure	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
8	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	high	_	ADJ	_	Degree=Pos	_	_	_	_
11	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	ATc	_	NOUN	_	Number=Sing	_	_	_	_
16	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	exceed	_	VERB	_	VerbForm=Inf	_	_	_	_
19	critical	_	ADJ	_	Degree=Pos	_	_	_	_
20	threshold	_	NOUN	_	Number=Sing	_	_	_	_
21	levels	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	ATc	_	NOUN	_	Number=Sing	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	induction	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	effector	_	NOUN	_	Number=Sing	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003392	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Direct	_	ADJ	_	Degree=Pos	_	_	_	_
2	demonstration	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NFATp	_	PROPN	_	Number=Sing	_	_	_	_
5	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	localization	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	HT	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	using	_	VERB	_	VerbForm=Ger	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
19	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
20	antibody	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	number	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	NFAT	_	NOUN	_	Degree=Pos	_	_	_	_
21	DNA	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	following	_	VERB	_	VerbForm=Ger	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	lines	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	evidence	_	NOUN	_	Number=Sing	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	substrate	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	serine	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	threonine	_	ADJ	_	Number=Sing	_	_	_	_
19	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
4	antibody	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	murine	_	VERB	_	VerbForm=Inf	_	_	_	_
7	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	Western	_	ADJ	_	Degree=Pos	_	_	_	_
10	blot	_	NOUN	_	Number=Sing	_	_	_	_
11	analysis	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	various	_	ADJ	_	Degree=Pos	_	_	_	_
14	mouse	_	NOUN	_	Number=Sing	_	_	_	_
15	tissues	_	NOUN	_	Number=Plur	_	_	_	_
16	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	110	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	SYM	_	_	_	_	_	_
21	130	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kDa	_	NOUN	_	Number=Sing	_	_	_	_
24	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	highly	_	ADV	_	_	_	_	_	_
28	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	thymus	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	spleen	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	immunoprecipitated	_	VERB	_	Degree=Pos	_	_	_	_
4	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
7	HT	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
13	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	NFATp	_	PROPN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vitro	_	NOUN	_	Number=Sing	_	_	_	_
27	substrate	_	NOUN	_	Number=Sing	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	NFATp	_	PROPN	_	Number=Sing	_	_	_	_
2	immunoprecipitated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	32	_	NUM	_	NumType=Card	_	_	_	_
5	P-labeled	_	ADJ	_	Number=Sing	_	_	_	_
6	HT	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	migrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	approximately	_	ADV	_	_	_	_	_	_
14	120	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kDa	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
7	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	decrease	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
14	weight	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	loss	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	32P	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
26	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NFATp	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	localization	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	fraction	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	events	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	preincubation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	FK506	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
17	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	NFATp	_	PROPN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
28	substrate	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003398	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	p105	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	p98	_	PROPN	_	Number=Sing	_	_	_	_
4	precursor	_	NOUN	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	active	_	ADJ	_	Degree=Pos	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	PROPN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	mediated	_	VERB	_	Degree=Pos	_	_	_	_
17	signal	_	NOUN	_	Number=Sing	_	_	_	_
18	transduction	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Rel	_	PROPN	_	Number=Sing	_	_	_	_
3	/	_	PUNCT	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	PROPN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	family	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
17	subgroups	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	undergo	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
23	processing	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	SWI6	_	PROPN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	ankyrin	_	NOUN	_	Number=Sing	_	_	_	_
29	repeats	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
32	carboxyl	_	NOUN	_	Number=Sing	_	_	_	_
33	termini	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	p105	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	p98	_	NUM	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
42	without	_	ADP	_	_	_	_	_	_
43	such	_	ADJ	_	Degree=Pos	_	_	_	_
44	repeats	_	NOUN	_	Number=Plur	_	_	_	_
45	that	_	PRON	_	PronType=Rel	_	_	_	_
46	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
47	not	_	PART	_	_	_	_	_	_
48	require	_	VERB	_	VerbForm=Inf	_	_	_	_
49	processing	_	NOUN	_	Number=Sing	_	_	_	_
50	(	_	PUNCT	_	_	_	_	_	_
51	p65	_	NOUN	_	Number=Sing	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	c	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	Rel	_	NOUN	_	Number=Sing	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	RelB	_	PROPN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	and	_	CCONJ	_	_	_	_	_	_
60	Dorsal	_	NOUN	_	Number=Sing	_	_	_	_
61	)	_	PUNCT	_	_	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	p105	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	p98	_	NOUN	_	Number=Sing	_	_	_	_
8	precursors	_	NOUN	_	Number=Plur	_	_	_	_
9	share	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	functional	_	ADJ	_	Degree=Pos	_	_	_	_
11	properties	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	I	_	PRON	_	Number=Sing	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	also	_	ADV	_	_	_	_	_	_
21	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	SWI6	_	PROPN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	ankyrin	_	NOUN	_	Number=Sing	_	_	_	_
25	repeats	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	p105	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	p98	_	NOUN	_	Number=Sing	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	form	_	VERB	_	VerbForm=Inf	_	_	_	_
9	stable	_	ADJ	_	Number=Sing	_	_	_	_
10	complexes	_	NOUN	_	Number=Plur	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	other	_	ADJ	_	Degree=Pos	_	_	_	_
13	Rel	_	PROPN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	PROPN	_	Number=Sing	_	_	_	_
19	family	_	NOUN	_	Number=Sing	_	_	_	_
20	members	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	including	_	VERB	_	VerbForm=Ger	_	_	_	_
23	p65	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Association	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	precursors	_	NOUN	_	Number=Plur	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
9	retention	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	either	_	CCONJ	_	_	_	_	_	_
12	p65	_	NOUN	_	Number=Sing	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	both	_	DET	_	_	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Int	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	otherwise	_	ADV	_	_	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	complexes	_	NOUN	_	Number=Plur	_	_	_	_
3	undergo	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	stimulus	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
7	processing	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
10	active	_	ADJ	_	Degree=Pos	_	_	_	_
11	p50/c	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	Rel	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	p55/c	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	Rel	_	NOUN	_	Number=Sing	_	_	_	_
18	complexes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	pathway	_	NOUN	_	Number=Sing	_	_	_	_
7	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	which	_	DET	_	PronType=Rel	_	_	_	_
17	processing	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	precursors	_	NOUN	_	Number=Plur	_	_	_	_
21	rather	_	ADV	_	_	_	_	_	_
22	than	_	ADP	_	_	_	_	_	_
23	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
26	kappa	_	PROPN	_	Number=Sing	_	_	_	_
27	B	_	PROPN	_	Number=Sing	_	_	_	_
28	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	major	_	ADJ	_	Degree=Pos	_	_	_	_
31	role	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003399	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	tyk2	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	differential	_	ADJ	_	Degree=Pos	_	_	_	_
15	assembly	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
21	complexes	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	by	_	SCONJ	_	_	_	_	_	_
10	driving	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	progression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	immune	_	ADJ	_	Degree=Pos	_	_	_	_
15	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
16	such	_	ADJ	_	Degree=Pos	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	effects	_	NOUN	_	Number=Plur	_	_	_	_
23	predominate	_	ADJ	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	10	_	NUM	_	NumType=Card	_	_	_	_
16	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
18	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	signal	_	NOUN	_	Number=Sing	_	_	_	_
22	transducers	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	activators	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	differential	_	ADJ	_	Degree=Pos	_	_	_	_
36	manner	_	NOUN	_	Number=Sing	_	_	_	_
37	such	_	ADJ	_	Degree=Pos	_	_	_	_
38	that	_	SCONJ	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	relative	_	ADJ	_	Degree=Pos	_	_	_	_
41	formation	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	homo	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
47	varies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
48	between	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	two	_	NUM	_	NumType=Card	_	_	_	_
51	cell	_	NOUN	_	Number=Sing	_	_	_	_
52	types	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	novel	_	NOUN	_	Number=Sing	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	STAT	_	PROPN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	M	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	r	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	70	_	NUM	_	NumType=Card	_	_	_	_
22	kDa	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	anti-STAT3	_	NOUN	_	Number=Sing	_	_	_	_

1	Ab	_	PROPN	_	Number=Sing	_	_	_	_
2	but	_	CCONJ	_	_	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	monocytes	_	VERB	_	Number=Plur	_	_	_	_
11	results	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	ligand	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
18	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	tyk2	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	not	_	ADV	_	_	_	_	_	_
26	Jak2	_	NOUN	_	Number=Sing	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Selective	_	ADJ	_	Degree=Pos	_	_	_	_
2	modulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	immune	_	ADJ	_	Degree=Pos	_	_	_	_
5	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	such	_	ADJ	_	Degree=Pos	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	may	_	AUX	_	VerbForm=Fin	_	_	_	_
19	result	_	VERB	_	VerbForm=Inf	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	part	_	NOUN	_	Number=Sing	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	differential	_	ADJ	_	Degree=Pos	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	STAT	_	NOUN	_	Number=Sing	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	pairs	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003405	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Impaired	_	ADJ	_	Degree=Pos	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	DQ2	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	DQ8	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
10	HSV	_	PROPN	_	Number=Sing	_	_	_	_
11	VP16	_	NOUN	_	Number=Sing	_	_	_	_
12	peptide	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	DQA1*0501	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	DQB1*0302	_	NUM	_	Number=Sing	_	_	_	_
18	trans	_	NOUN	_	Number=Sing	_	_	_	_
19	class	_	NOUN	_	Number=Sing	_	_	_	_
20	II	_	NUM	_	NumType=Card	_	_	_	_
21	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	DQalpha	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	DQbeta	_	PROPN	_	Number=Sing	_	_	_	_
4	trans	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	heterodimeric	_	ADJ	_	Degree=Pos	_	_	_	_
6	HLA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	DQ	_	NOUN	_	Number=Sing	_	_	_	_
9	molecules	_	NOUN	_	Number=Plur	_	_	_	_
10	form	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	individuals	_	NOUN	_	Number=Plur	_	_	_	_
13	heterozygous	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	DQ2	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	DQ8	_	NOUN	_	Number=Sing	_	_	_	_
19	specificities	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Unique	_	ADJ	_	Degree=Pos	_	_	_	_
2	functions	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	disease	_	NOUN	_	Number=Sing	_	_	_	_
5	associations	_	NOUN	_	Number=Plur	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	postulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	such	_	ADJ	_	Degree=Pos	_	_	_	_
11	trans	_	NOUN	_	Number=Plur	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dimers	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	different	_	ADJ	_	Degree=Pos	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	cis	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	DQ	_	NOUN	_	Number=Sing	_	_	_	_
24	molecules	_	NOUN	_	Number=Plur	_	_	_	_
25	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	corresponding	_	VERB	_	Degree=Pos	_	_	_	_
29	haplotypes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	ability	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	trans	_	NOUN	_	Number=Plur	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dimer	_	NOUN	_	Number=Sing	_	_	_	_
10	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	HLA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	DQA1*0501/DQB1*0302	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	peptide	_	NOUN	_	Number=Sing	_	_	_	_
19	antigen	_	NOUN	_	Number=Sing	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	DQ	_	NOUN	_	Number=Sing	_	_	_	_
24	molecules	_	NOUN	_	Number=Plur	_	_	_	_
25	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	both	_	DET	_	_	_	_	_	_
28	parental	_	ADJ	_	Degree=Pos	_	_	_	_
29	haplotypes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Markedly	_	ADV	_	_	_	_	_	_
2	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	use	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	different	_	ADJ	_	Degree=Pos	_	_	_	_
14	anchor	_	NOUN	_	Number=Sing	_	_	_	_
15	residues	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	changes	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	levels	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	DQ	_	NOUN	_	Number=Sing	_	_	_	_
23	cis	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dimer	_	NOUN	_	Number=Sing	_	_	_	_
26	availability	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	peptide	_	NOUN	_	Number=Sing	_	_	_	_
29	binding	_	VERB	_	Number=Sing	_	_	_	_
30	interactions	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003411	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	L-	_	PUNCT	_	Number=Sing	_	_	_	_
6	selectin	_	ADJ	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	fresh	_	ADJ	_	Degree=Pos	_	_	_	_
10	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	adult	_	NOUN	_	Number=Sing	_	_	_	_
14	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
15	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	can	_	AUX	_	VerbForm=Fin	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	transactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
23	lymphotropic	_	ADJ	_	Degree=Pos	_	_	_	_
24	virus	_	NOUN	_	Number=Sing	_	_	_	_
25	type	_	NOUN	_	Number=Sing	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	Tax	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	L	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	selectin	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
7	molecule	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	selectin	_	ADJ	_	Number=Sing	_	_	_	_
11	family	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	initial	_	ADJ	_	Degree=Pos	_	_	_	_
16	step	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
22	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	L-	_	PUNCT	_	Number=Sing	_	_	_	_
9	selectin	_	NOUN	_	Degree=Pos	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	downregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
19	levels	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
9	into	_	ADP	_	_	_	_	_	_
10	organs	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	L	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	selectin	_	NOUN	_	Number=Sing	_	_	_	_
22	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	fresh	_	ADJ	_	Degree=Pos	_	_	_	_
25	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	adult	_	NOUN	_	Number=Sing	_	_	_	_
29	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
30	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	ATL	_	PROPN	_	_	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	patients	_	NOUN	_	Number=Plur	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	response	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	L	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	selectin	_	NOUN	_	Number=Sing	_	_	_	_
44	promoter	_	NOUN	_	Number=Sing	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	human	_	ADJ	_	Degree=Pos	_	_	_	_
47	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
48	lymphotropic	_	ADJ	_	Degree=Pos	_	_	_	_
49	virus	_	NOUN	_	Number=Sing	_	_	_	_
50	type	_	NOUN	_	Number=Sing	_	_	_	_
51	1	_	NUM	_	NumType=Card	_	_	_	_
52	(	_	PUNCT	_	_	_	_	_	_
53	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	1	_	NUM	_	NumType=Card	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	Tax	_	NOUN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	which	_	PRON	_	PronType=Rel	_	_	_	_
60	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
61	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
62	viral	_	ADJ	_	Degree=Pos	_	_	_	_
63	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
64	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	Flow	_	PROPN	_	Number=Sing	_	_	_	_
2	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	L-	_	PUNCT	_	Number=Sing	_	_	_	_
6	selectin	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	fresh	_	ADJ	_	Degree=Pos	_	_	_	_
11	ATL	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	along	_	ADP	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	other	_	ADJ	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	antigens	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	PROPN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	ATL	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	L-	_	PUNCT	_	_	_	_	_	_
11	selectin	_	VERB	_	Number=Sing	_	_	_	_
12	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	level	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	aberrantly	_	ADV	_	_	_	_	_	_
19	upregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	after	_	ADP	_	_	_	_	_	_
21	PMA	_	NOUN	_	Number=Sing	_	_	_	_
22	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	situ	_	NOUN	_	Number=Sing	_	_	_	_
5	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
6	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	L-	_	PUNCT	_	Number=Sing	_	_	_	_
11	selectin	_	NOUN	_	Number=Sing	_	_	_	_
12	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	infiltrating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	liver	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	two	_	NUM	_	NumType=Card	_	_	_	_
23	ATL	_	NOUN	_	Number=Sing	_	_	_	_
24	patients	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Intravenous	_	ADJ	_	Degree=Pos	_	_	_	_
2	injection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	rat	_	NOUN	_	Number=Sing	_	_	_	_
6	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
7	line	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	overexpresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	L	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	selectin	_	NOUN	_	Number=Sing	_	_	_	_
13	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	organ	_	ADJ	_	Degree=Pos	_	_	_	_
16	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Tax	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	JPX9	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	about	_	ADV	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	twofold	_	NOUN	_	Number=Sing	_	_	_	_
14	increase	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	levels	_	NOUN	_	Number=Plur	_	_	_	_
20	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	basal	_	ADJ	_	Degree=Pos	_	_	_	_
24	level	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Chloramphenicol	_	PROPN	_	Number=Sing	_	_	_	_
2	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	CAT	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	assay	_	NOUN	_	Number=Sing	_	_	_	_
7	after	_	ADP	_	_	_	_	_	_
8	transient	_	ADJ	_	Degree=Pos	_	_	_	_
9	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
10	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	about	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	fivefold	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	L	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	selectin	_	NOUN	_	Number=Sing	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	Tax	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	serum	_	NOUN	_	Number=Sing	_	_	_	_
3	level	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	shed	_	NOUN	_	Number=Sing	_	_	_	_
7	form	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	L	_	ADJ	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	selectin	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	significantly	_	ADV	_	_	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	ATL	_	DET	_	Number=Sing	_	_	_	_
17	patients	_	NOUN	_	Number=Plur	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	mean	_	VERB	_	Number=Sing	_	_	_	_
20	+/-	_	SYM	_	_	_	_	_	_
21	SD	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	4,215.4	_	NUM	_	NumType=Card	_	_	_	_
24	+/-	_	SYM	_	_	_	_	_	_
25	4,111	_	NUM	_	NumType=Card	_	_	_	_
26	ng	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	mL	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	asymptomatic	_	ADJ	_	Degree=Pos	_	_	_	_
35	carriers	_	NOUN	_	Number=Plur	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
38	blood	_	NOUN	_	Number=Sing	_	_	_	_
39	donors	_	NOUN	_	Number=Plur	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	mean	_	VERB	_	Number=Sing	_	_	_	_
42	+/-	_	SYM	_	_	_	_	_	_
43	SD	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	1,148.0	_	NUM	_	NumType=Card	_	_	_	_
46	+/-	_	SYM	_	_	_	_	_	_
47	269.0	_	NUM	_	NumType=Card	_	_	_	_
48	ng	_	NOUN	_	Number=Sing	_	_	_	_
49	/	_	PUNCT	_	_	_	_	_	_
50	mL	_	NOUN	_	Number=Sing	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	991.9	_	NUM	_	NumType=Card	_	_	_	_
53	+/-	_	SYM	_	_	_	_	_	_
54	224	_	NUM	_	NumType=Card	_	_	_	_
55	ng	_	NOUN	_	Number=Sing	_	_	_	_
56	/	_	PUNCT	_	_	_	_	_	_
57	mL	_	NOUN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	respectively	_	ADV	_	_	_	_	_	_
60	)	_	PUNCT	_	_	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	ATL	_	DET	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	constitutively	_	ADV	_	_	_	_	_	_
8	overexpress	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	L	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	selectin	_	NOUN	_	Degree=Pos	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	can	_	AUX	_	VerbForm=Fin	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	transactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	Tax	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	L	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	selectin	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	as	_	ADV	_	_	_	_	_	_
9	well	_	ADV	_	Degree=Pos	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	ATL	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	may	_	AUX	_	VerbForm=Fin	_	_	_	_
19	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	basis	_	NOUN	_	Number=Sing	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	ATL	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	attach	_	VERB	_	VerbForm=Inf	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
29	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	transmigration	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	organ	_	ADJ	_	Number=Sing	_	_	_	_
36	infitration	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003414	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nonopsonic	_	ADJ	_	Degree=Pos	_	_	_	_
2	phagocytosis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Pseudomonas	_	PROPN	_	Number=Sing	_	_	_	_
5	aeruginosa	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	polymorphonuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	presence	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
17	flagellum	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	nonopsonic	_	ADJ	_	Degree=Pos	_	_	_	_
6	phagocytosis	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Pseudomonas	_	PROPN	_	Number=Sing	_	_	_	_
9	aeruginosa	_	NOUN	_	Number=Sing	_	_	_	_
10	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
16	ligands	_	NOUN	_	Number=Plur	_	_	_	_
17	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	poorly	_	ADV	_	_	_	_	_	_
20	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	requisite	_	ADJ	_	Degree=Pos	_	_	_	_
5	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
6	ligands	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	studies	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	isogenic	_	ADJ	_	Degree=Pos	_	_	_	_
11	mutants	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	P.	_	PROPN	_	Number=Sing	_	_	_	_
14	aeruginosa	_	NOUN	_	Number=Sing	_	_	_	_
15	PAK	_	PROPN	_	Number=Sing	_	_	_	_
16	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
17	pili	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	flagella	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	RpoN	_	PROPN	_	Number=Sing	_	_	_	_
24	sigma	_	NOUN	_	Number=Sing	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	undertaken	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	RpoN	_	PROPN	_	Number=Sing	_	_	_	_
3	mutant	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
6	pili	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	flagella	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	nonpilus	_	ADJ	_	Degree=Pos	_	_	_	_
12	adhesins	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	bound	_	ADJ	_	Degree=Pos	_	_	_	_
15	poorly	_	ADV	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	ingestion	_	VERB	_	VerbForm=Inf	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Pili	_	PROPN	_	Number=Sing	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	absolutely	_	ADV	_	_	_	_	_	_
5	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	phagocytosis	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	P.	_	PROPN	_	Number=Sing	_	_	_	_
12	aeruginosa	_	PROPN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	presence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	flagellum	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	P.	_	PROPN	_	Number=Sing	_	_	_	_
13	aeruginosa	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	critical	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
22	internalization	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	bacterium	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	surface	_	NOUN	_	Number=Sing	_	_	_	_
34	ligand	_	NOUN	_	Number=Sing	_	_	_	_
35	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
38	assembly	_	NOUN	_	Number=Sing	_	_	_	_
39	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
40	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	nonopsonic	_	ADJ	_	Degree=Pos	_	_	_	_
45	phagocytosis	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003415	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
2	interactions	_	NOUN	_	Number=Plur	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	overlapping	_	VERB	_	Degree=Pos	_	_	_	_
5	binding	_	NOUN	_	VerbForm=Ger	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	serum	_	NOUN	_	Number=Sing	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	ELK	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	basal	_	ADJ	_	Degree=Pos	_	_	_	_
20	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
23	ester	_	NOUN	_	Number=Sing	_	_	_	_
24	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	primate	_	ADJ	_	Degree=Pos	_	_	_	_
27	cytomegalovirus	_	NOUN	_	Number=Sing	_	_	_	_
28	major	_	ADJ	_	Degree=Pos	_	_	_	_
29	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	early	_	ADJ	_	Degree=Pos	_	_	_	_
32	promoters	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	T-lymphocyte	_	ADJ	_	Number=Sing	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	types	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Cytomegalovirus	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	CMV	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	infection	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	nonpermissive	_	ADJ	_	Degree=Pos	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	many	_	ADJ	_	Degree=Pos	_	_	_	_
12	lymphoid	_	NOUN	_	Degree=Pos	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	types	_	NOUN	_	Number=Plur	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	can	_	AUX	_	VerbForm=Fin	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	differentiated	_	ADJ	_	Degree=Pos	_	_	_	_
23	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	elsewhere	_	ADV	_	_	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	major	_	ADJ	_	Degree=Pos	_	_	_	_
9	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	early	_	ADJ	_	Degree=Pos	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	MIE	_	X	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cycle	_	NOUN	_	Number=Sing	_	_	_	_
19	infectious	_	ADJ	_	Degree=Pos	_	_	_	_
20	progeny	_	NOUN	_	Number=Sing	_	_	_	_
21	virus	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	can	_	AUX	_	VerbForm=Fin	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	otherwise	_	ADV	_	_	_	_	_	_
28	nonpermissive	_	ADJ	_	Degree=Pos	_	_	_	_
29	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	like	_	ADP	_	_	_	_	_	_
32	U	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	937	_	NUM	_	NumType=Card	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	cultures	_	NOUN	_	Number=Plur	_	_	_	_
37	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	either	_	CCONJ	_	_	_	_	_	_
40	human	_	ADJ	_	Degree=Pos	_	_	_	_
41	CMV	_	PROPN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	HCMV	_	PROPN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	or	_	CCONJ	_	_	_	_	_	_
46	simian	_	ADJ	_	Degree=Pos	_	_	_	_
47	CMV	_	PROPN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	SCMV	_	PROPN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	by	_	ADP	_	_	_	_	_	_
52	treatment	_	NOUN	_	Number=Sing	_	_	_	_
53	with	_	ADP	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
56	ester	_	NOUN	_	Number=Sing	_	_	_	_
57	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	13	_	NUM	_	NumType=Card	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	acetate	_	NOUN	_	Number=Sing	_	_	_	_
62	(	_	PUNCT	_	_	_	_	_	_
63	TPA	_	NOUN	_	Number=Sing	_	_	_	_
64	)	_	PUNCT	_	_	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	multicopy	_	ADJ	_	Degree=Pos	_	_	_	_
3	basal	_	ADJ	_	Number=Sing	_	_	_	_
4	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
5	motifs	_	NOUN	_	Number=Plur	_	_	_	_
6	within	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	SCMV	_	PROPN	_	Number=Sing	_	_	_	_
9	MIE	_	PROPN	_	Number=Sing	_	_	_	_
10	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	namely	_	ADV	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	11	_	NUM	_	NumType=Card	_	_	_	_
15	copies	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	16	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	bp	_	NOUN	_	Number=Sing	_	_	_	_
21	cyclic	_	ADJ	_	Number=Sing	_	_	_	_
22	AMP	_	NOUN	_	Number=Sing	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	element	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	CRE	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	3	_	NUM	_	NumType=Card	_	_	_	_
30	copies	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	novel	_	NOUN	_	Number=Sing	_	_	_	_
33	17	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	bp	_	NOUN	_	Number=Sing	_	_	_	_
36	serum	_	NOUN	_	Number=Sing	_	_	_	_
37	response	_	NOUN	_	Number=Sing	_	_	_	_
38	factor	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	SRF	_	PROPN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	binding	_	NOUN	_	VerbForm=Ger	_	_	_	_
43	sites	_	NOUN	_	Number=Plur	_	_	_	_
44	referred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	as	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	SNE	_	PROPN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	SRF	_	PROPN	_	Number=Sing	_	_	_	_
51	/	_	PUNCT	_	_	_	_	_	_
52	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	like	_	ADJ	_	Degree=Pos	_	_	_	_
55	element	_	NOUN	_	Number=Sing	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	as	_	ADV	_	_	_	_	_	_
59	well	_	ADV	_	Degree=Pos	_	_	_	_
60	as	_	ADP	_	_	_	_	_	_
61	four	_	NUM	_	NumType=Card	_	_	_	_
62	classical	_	ADJ	_	Degree=Pos	_	_	_	_
63	NFkappaB	_	NOUN	_	Number=Sing	_	_	_	_
64	sites	_	NOUN	_	Number=Plur	_	_	_	_
65	within	_	ADP	_	_	_	_	_	_
66	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
67	HCMV	_	PROPN	_	Number=Sing	_	_	_	_
68	version	_	NOUN	_	Number=Sing	_	_	_	_
69	,	_	PUNCT	_	_	_	_	_	_
70	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
71	to	_	ADP	_	_	_	_	_	_
72	TPA	_	NOUN	_	Number=Sing	_	_	_	_
73	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
74	in	_	ADP	_	_	_	_	_	_
75	transient	_	ADJ	_	Degree=Pos	_	_	_	_
76	assays	_	NOUN	_	Number=Plur	_	_	_	_
77	in	_	ADP	_	_	_	_	_	_
78	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
79	and	_	CCONJ	_	_	_	_	_	_
80	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
81	types	_	NOUN	_	Number=Plur	_	_	_	_
82	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	SCMV	_	NOUN	_	Number=Sing	_	_	_	_
3	SNE	_	NOUN	_	Number=Sing	_	_	_	_
4	sites	_	NOUN	_	Number=Plur	_	_	_	_
5	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	potential	_	ADJ	_	Degree=Pos	_	_	_	_
7	overlapping	_	VERB	_	VerbForm=Ger	_	_	_	_
8	core	_	NOUN	_	Number=Sing	_	_	_	_
9	recognition	_	NOUN	_	Number=Sing	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	motifs	_	NOUN	_	Number=Plur	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	SRF	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	Rel	_	PROPN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	ETS	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	YY1	_	NOUN	_	Number=Sing	_	_	_	_
23	class	_	NOUN	_	Number=Sing	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factors	_	NOUN	_	Number=Plur	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	fail	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	either	_	CCONJ	_	_	_	_	_	_
32	serum	_	NOUN	_	Number=Sing	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	tumor	_	NOUN	_	Number=Sing	_	_	_	_
35	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
36	factor	_	NOUN	_	Number=Sing	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	evaluate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	TPA	_	NOUN	_	Number=Sing	_	_	_	_
9	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	SNE	_	NOUN	_	Number=Sing	_	_	_	_
13	motifs	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	related	_	ADJ	_	Degree=Pos	_	_	_	_
18	16	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	bp	_	NOUN	_	Number=Sing	_	_	_	_
21	SEE	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	SRF	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	ETS	_	NOUN	_	Number=Sing	_	_	_	_
26	element	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	motif	_	NOUN	_	Number=Sing	_	_	_	_
29	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	HCMV	_	PROPN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	chimpanzee	_	NOUN	_	Number=Sing	_	_	_	_
35	CMV	_	NOUN	_	Number=Sing	_	_	_	_
36	MIE	_	PROPN	_	Number=Sing	_	_	_	_
37	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
40	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
41	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	functional	_	ADJ	_	Degree=Pos	_	_	_	_
44	responses	_	NOUN	_	Number=Plur	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	protein	_	NOUN	_	Number=Sing	_	_	_	_
47	binding	_	VERB	_	Number=Sing	_	_	_	_
48	properties	_	NOUN	_	Number=Plur	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	multimerized	_	VERB	_	Degree=Pos	_	_	_	_
51	wild	_	ADJ	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	type	_	NOUN	_	Number=Sing	_	_	_	_
54	and	_	CCONJ	_	_	_	_	_	_
55	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
56	elements	_	NOUN	_	Number=Plur	_	_	_	_
57	added	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
58	upstream	_	NOUN	_	_	_	_	_	_
59	to	_	ADP	_	_	_	_	_	_
60	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
61	SCMV	_	PROPN	_	Number=Sing	_	_	_	_
62	MIE	_	PROPN	_	Number=Sing	_	_	_	_
63	or	_	CCONJ	_	_	_	_	_	_
64	simian	_	ADJ	_	Degree=Pos	_	_	_	_
65	virus	_	NOUN	_	Number=Sing	_	_	_	_
66	40	_	NUM	_	NumType=Card	_	_	_	_
67	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
68	promoter	_	NOUN	_	Number=Sing	_	_	_	_
69	regions	_	NOUN	_	Number=Plur	_	_	_	_
70	in	_	ADP	_	_	_	_	_	_
71	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
72	U-937	_	PROPN	_	Number=Sing	_	_	_	_
73	,	_	PUNCT	_	_	_	_	_	_
74	K	_	PROPN	_	Number=Sing	_	_	_	_
75	-	_	PUNCT	_	_	_	_	_	_
76	562	_	NUM	_	NumType=Card	_	_	_	_
77	,	_	PUNCT	_	_	_	_	_	_
78	HL	_	NOUN	_	Number=Sing	_	_	_	_
79	-	_	PUNCT	_	_	_	_	_	_
80	60	_	NUM	_	NumType=Card	_	_	_	_
81	,	_	PUNCT	_	_	_	_	_	_
82	THP	_	NOUN	_	Number=Sing	_	_	_	_
83	-	_	PUNCT	_	_	_	_	_	_
84	1	_	NUM	_	NumType=Card	_	_	_	_
85	,	_	PUNCT	_	_	_	_	_	_
86	and	_	CCONJ	_	_	_	_	_	_
87	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
88	cell	_	NOUN	_	Number=Sing	_	_	_	_
89	lines	_	NOUN	_	Number=Plur	_	_	_	_
90	.	_	PUNCT	_	_	_	_	_	_

1	Unlike	_	ADP	_	_	_	_	_	_
2	classical	_	ADJ	_	Degree=Pos	_	_	_	_
3	NFkappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	sites	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	neither	_	CCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	SNE	_	NOUN	_	Number=Sing	_	_	_	_
9	nor	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	SEE	_	NOUN	_	Number=Sing	_	_	_	_
12	motif	_	NOUN	_	Number=Sing	_	_	_	_
13	responded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
16	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
19	acid	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	TPA	_	NOUN	_	Number=Sing	_	_	_	_
5	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	both	_	DET	_	_	_	_	_	_
8	CMV	_	PROPN	_	Number=Sing	_	_	_	_
9	elements	_	NOUN	_	Number=Plur	_	_	_	_
10	proved	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
13	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
14	interactions	_	NOUN	_	Number=Plur	_	_	_	_
15	between	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	core	_	NOUN	_	Number=Sing	_	_	_	_
18	SRF	_	PROPN	_	Number=Sing	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	CCATATATGG	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	adjacent	_	ADJ	_	Number=Sing	_	_	_	_
27	inverted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	ETS	_	NOUN	_	Number=Sing	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	motifs	_	NOUN	_	Number=Plur	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	TTCC	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	which	_	PRON	_	PronType=Rel	_	_	_	_
36	correlated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	directly	_	ADV	_	_	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	formation	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	bound	_	ADJ	_	Degree=Pos	_	_	_	_
43	tripartite	_	ADJ	_	Degree=Pos	_	_	_	_
44	complex	_	NOUN	_	Number=Sing	_	_	_	_
45	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
46	both	_	CCONJ	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
49	SRF	_	NOUN	_	Number=Sing	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	ELK	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	1	_	NUM	_	NumType=Card	_	_	_	_
54	proteins	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	complex	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	more	_	ADV	_	_	_	_	_	_
6	abundant	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	U	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	937	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	K	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	562	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	extracts	_	NOUN	_	Number=Plur	_	_	_	_
20	than	_	ADP	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	Raji	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	HF	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	BALB	_	PROPN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	c	_	NOUN	_	Number=Sing	_	_	_	_
29	3T3	_	NUM	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	HL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	60	_	NUM	_	NumType=Card	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	but	_	CCONJ	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	binding	_	NOUN	_	Number=Sing	_	_	_	_
40	activity	_	NOUN	_	Number=Sing	_	_	_	_
41	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
42	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	only	_	ADV	_	_	_	_	_	_
44	twofold	_	NOUN	_	Number=Sing	_	_	_	_
45	after	_	ADP	_	_	_	_	_	_
46	TPA	_	NOUN	_	Number=Sing	_	_	_	_
47	treatment	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	40	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	fold	_	NOUN	_	Number=Sing	_	_	_	_
5	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
8	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	four	_	NUM	_	NumType=Card	_	_	_	_
13	tandem	_	NOUN	_	Number=Sing	_	_	_	_
14	repeats	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	SNE	_	NOUN	_	Number=Sing	_	_	_	_
18	could	_	AUX	_	VerbForm=Fin	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	within	_	ADP	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	h	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	up	_	ADP	_	_	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	250	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	fold	_	NOUN	_	Number=Sing	_	_	_	_
31	within	_	ADP	_	_	_	_	_	_
32	6	_	NUM	_	NumType=Card	_	_	_	_
33	h	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	after	_	ADP	_	_	_	_	_	_
36	addition	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	TPA	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	DNA	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	U	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	937	_	NUM	_	NumType=Card	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
49	that	_	SCONJ	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
52	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
53	likely	_	ADV	_	_	_	_	_	_
54	to	_	PART	_	_	_	_	_	_
55	be	_	AUX	_	VerbForm=Inf	_	_	_	_
56	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
57	true	_	ADJ	_	Degree=Pos	_	_	_	_
58	protein	_	NOUN	_	Number=Sing	_	_	_	_
59	kinase	_	NOUN	_	Number=Sing	_	_	_	_
60	C	_	NOUN	_	Number=Sing	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	mediated	_	VERB	_	Degree=Pos	_	_	_	_
63	signal	_	NOUN	_	Number=Sing	_	_	_	_
64	transduction	_	NOUN	_	Number=Sing	_	_	_	_
65	event	_	NOUN	_	Number=Sing	_	_	_	_
66	rather	_	ADV	_	_	_	_	_	_
67	than	_	ADP	_	_	_	_	_	_
68	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
69	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
70	response	_	NOUN	_	Number=Sing	_	_	_	_
71	.	_	PUNCT	_	_	_	_	_	_

1	Slight	_	ADJ	_	Degree=Pos	_	_	_	_
2	differences	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	core	_	NOUN	_	Number=Sing	_	_	_	_
9	SRF	_	PROPN	_	Number=Sing	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	classical	_	ADJ	_	Degree=Pos	_	_	_	_
18	c-Fos	_	NOUN	_	Number=Sing	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	serum	_	NOUN	_	Number=Sing	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	element	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	together	_	ADV	_	_	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	differences	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	spacing	_	NOUN	_	Number=Sing	_	_	_	_
30	between	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	SRF	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	ETS	_	NOUN	_	Number=Sing	_	_	_	_
35	motifs	_	NOUN	_	Number=Plur	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	account	_	VERB	_	VerbForm=Inf	_	_	_	_
40	for	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	inability	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	SCMV	_	PROPN	_	Number=Sing	_	_	_	_
46	SNEs	_	PROPN	_	Number=Plur	_	_	_	_
47	to	_	PART	_	_	_	_	_	_
48	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
49	to	_	ADP	_	_	_	_	_	_
50	serum	_	NOUN	_	Number=Sing	_	_	_	_
51	induction	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003417	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	Tax	_	NOUN	_	Number=Sing	_	_	_	_
8	associates	_	VERB	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	negatively	_	ADV	_	_	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B2	_	NUM	_	Number=Sing	_	_	_	_
20	p100	_	NUM	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	product	_	NOUN	_	Number=Sing	_	_	_	_
23	:	_	PUNCT	_	_	_	_	_	_
24	implications	_	NOUN	_	Number=Plur	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	viral	_	ADJ	_	Degree=Pos	_	_	_	_
27	latency	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	etiologic	_	ADJ	_	Degree=Pos	_	_	_	_
15	agent	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	adult	_	NOUN	_	Number=Sing	_	_	_	_
19	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
20	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	aggressive	_	ADJ	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	often	_	ADV	_	_	_	_	_	_
26	fatal	_	ADJ	_	Degree=Pos	_	_	_	_
27	malignancy	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	CD4	_	NOUN	_	Number=Sing	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	essential	_	ADJ	_	Degree=Pos	_	_	_	_
7	40	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kDa	_	NOUN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	Tax	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	only	_	ADV	_	_	_	_	_	_
16	transactivates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	long	_	ADJ	_	Degree=Pos	_	_	_	_
19	terminal	_	NOUN	_	Number=Sing	_	_	_	_
20	repeat	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
23	retrovirus	_	NOUN	_	Number=Sing	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	also	_	ADV	_	_	_	_	_	_
26	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	array	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
31	genes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
4	transformation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	likely	_	ADV	_	_	_	_	_	_
9	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	deregulated	_	VERB	_	Degree=Pos	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	various	_	ADJ	_	Degree=Pos	_	_	_	_
15	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	normally	_	ADV	_	_	_	_	_	_
19	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	lymphocyte	_	ADJ	_	Degree=Pos	_	_	_	_
21	growth	_	NOUN	_	Number=Sing	_	_	_	_
22	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	altered	_	VERB	_	Degree=Pos	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	various	_	ADJ	_	Degree=Pos	_	_	_	_
28	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
29	host	_	NOUN	_	Number=Sing	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	factors	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	particular	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	Tax	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	capable	_	ADJ	_	Degree=Pos	_	_	_	_
7	of	_	SCONJ	_	_	_	_	_	_
8	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	various	_	ADJ	_	Degree=Pos	_	_	_	_
15	host	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	including	_	VERB	_	VerbForm=Ger	_	_	_	_
20	members	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	Rel	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	CREB	_	NOUN	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	ATF	_	PROPN	_	Number=Sing	_	_	_	_
33	families	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	as	_	ADV	_	_	_	_	_	_
36	well	_	ADV	_	Degree=Pos	_	_	_	_
37	as	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
40	factors	_	NOUN	_	Number=Plur	_	_	_	_
41	HEB	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	1	_	NUM	_	NumType=Card	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	p67SRF	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	additional	_	ADJ	_	Degree=Pos	_	_	_	_
3	distinguishing	_	ADJ	_	Degree=Pos	_	_	_	_
4	characteristic	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	infection	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	profound	_	ADJ	_	Degree=Pos	_	_	_	_
13	state	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	viral	_	ADJ	_	Degree=Pos	_	_	_	_
16	latency	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	present	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	SCONJ	_	_	_	_	_	_
21	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	primary	_	ADJ	_	Degree=Pos	_	_	_	_
23	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	Tax	_	NOUN	_	Number=Sing	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	physically	_	ADV	_	_	_	_	_	_
14	associate	_	VERB	_	VerbForm=Inf	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	p100	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	product	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	Rel	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	related	_	ADJ	_	Degree=Pos	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B2	_	ADJ	_	Degree=Pos	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	transfected	_	VERB	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	I-infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
14	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
15	lines	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	physical	_	ADJ	_	Degree=Pos	_	_	_	_
5	interaction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Tax	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	p100	_	NOUN	_	NumType=Card	_	_	_	_
10	leads	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	Tax	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	I	_	NOUN	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
27	virus	_	NOUN	_	Number=Sing	_	_	_	_
28	type	_	NOUN	_	Number=Sing	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	long	_	ADJ	_	Degree=Pos	_	_	_	_
31	terminal	_	NOUN	_	Number=Sing	_	_	_	_
32	repeats	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	reflecting	_	VERB	_	VerbForm=Ger	_	_	_	_
35	p100	_	NUM	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
38	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
39	sequestration	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	normally	_	ADV	_	_	_	_	_	_
43	nuclearly	_	ADV	_	_	_	_	_	_
44	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	Tax	_	NOUN	_	Number=Sing	_	_	_	_
46	protein	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	mutant	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Tax	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	selectively	_	ADV	_	_	_	_	_	_
10	fails	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	associate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	p100	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	003003419	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	direct	_	ADJ	_	Degree=Pos	_	_	_	_
3	interaction	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	adaptor	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	b	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	zap	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	70	_	NUM	_	NumType=Card	_	_	_	_
17	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	positive	_	ADJ	_	Degree=Pos	_	_	_	_
20	signal	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Engagement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	TCR	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CD3	_	PROPN	_	Number=Sing	_	_	_	_
11	complex	_	NOUN	_	Number=Sing	_	_	_	_
12	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
15	increase	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	activities	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Src-family	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	Syk	_	PROPN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	Zap	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	70	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	family	_	NOUN	_	Number=Sing	_	_	_	_
29	kinases	_	NOUN	_	Number=Plur	_	_	_	_
30	[	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	]	_	PUNCT	_	_	_	_	_	_
33	[	_	PUNCT	_	_	_	_	_	_
34	2	_	X	_	_	_	_	_	_
35	]	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	kinases	_	NOUN	_	Number=Plur	_	_	_	_
4	then	_	ADV	_	PronType=Dem	_	_	_	_
5	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
8	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
11	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	eventually	_	ADV	_	_	_	_	_	_
15	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	prominent	_	ADJ	_	Degree=Pos	_	_	_	_
5	substrates	_	NOUN	_	Number=Plur	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	kinases	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	adaptor	_	NOUN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	Cbl	_	NOUN	_	Number=Sing	_	_	_	_
14	[	_	PUNCT	_	_	_	_	_	_
15	3	_	NUM	_	NumType=Card	_	_	_	_
16	]	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	recent	_	ADJ	_	Degree=Pos	_	_	_	_
19	studies	_	NOUN	_	Number=Plur	_	_	_	_
20	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
23	negatively	_	ADV	_	_	_	_	_	_
24	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
26	kinases	_	NOUN	_	Number=Plur	_	_	_	_
27	such	_	ADJ	_	Degree=Pos	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	Syk	_	PROPN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	Zap	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	70	_	NUM	_	NumType=Card	_	_	_	_
34	[	_	PUNCT	_	_	_	_	_	_
35	4	_	NUM	_	NumType=Card	_	_	_	_
36	]	_	PUNCT	_	_	_	_	_	_

1	[	_	PUNCT	_	_	_	_	_	_
2	5	_	X	_	_	_	_	_	_
3	]	_	PUNCT	_	_	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	b	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	homologue	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	widely	_	ADV	_	_	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	many	_	ADJ	_	Degree=Pos	_	_	_	_
15	tissues	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	including	_	VERB	_	VerbForm=Ger	_	_	_	_
19	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	[	_	PUNCT	_	_	_	_	_	_
22	6	_	NUM	_	NumType=Card	_	_	_	_
23	]	_	PUNCT	_	_	_	_	_	_
24	[	_	PUNCT	_	_	_	_	_	_
25	7	_	NUM	_	NumType=Card	_	_	_	_
26	]	_	PUNCT	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	b	_	NOUN	_	Number=Sing	_	_	_	_
4	undergoes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	upon	_	ADP	_	_	_	_	_	_
9	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	TCR	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
15	receptors	_	NOUN	_	Number=Plur	_	_	_	_
16	[	_	PUNCT	_	_	_	_	_	_
17	8	_	NUM	_	NumType=Card	_	_	_	_
18	]	_	PUNCT	_	_	_	_	_	_
19	[	_	PUNCT	_	_	_	_	_	_
20	9	_	NUM	_	NumType=Card	_	_	_	_
21	]	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	b	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	however	_	ADV	_	_	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	b	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	loss	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	function	_	NOUN	_	Number=Sing	_	_	_	_
7	mutation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	b	_	NOUN	_	Number=Sing	_	_	_	_
12	disrupted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	interaction	_	NOUN	_	Number=Sing	_	_	_	_
15	between	_	ADP	_	_	_	_	_	_
16	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	b	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	Zap	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	70	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	nearly	_	ADV	_	_	_	_	_	_
25	completely	_	ADV	_	_	_	_	_	_
26	abrogated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	b-mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Unlike	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	proposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	negative	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulator	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
13	results	_	NOUN	_	Number=Plur	_	_	_	_
14	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
18	homologue	_	PROPN	_	Number=Sing	_	_	_	_
19	Cbl	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	b	_	PROPN	_	Number=Sing	_	_	_	_
22	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	positive	_	ADJ	_	Degree=Pos	_	_	_	_
25	role	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
28	signaling	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	most	_	ADV	_	_	_	_	_	_
31	likely	_	ADJ	_	_	_	_	_	_
32	via	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	direct	_	ADJ	_	Degree=Pos	_	_	_	_
35	interaction	_	NOUN	_	Number=Sing	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
39	kinase	_	NOUN	_	Number=Sing	_	_	_	_
40	Zap	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	70	_	NUM	_	NumType=Card	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003421	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Disruption	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	SCL	_	NOUN	_	Number=Sing	_	_	_	_
6	locus	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	"	_	PUNCT	_	_	_	_	_	_
9	illegitimate	_	VERB	_	Number=Sing	_	_	_	_
10	"	_	PUNCT	_	_	_	_	_	_
11	V	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	D	_	NOUN	_	Number=Sing	_	_	_	_
15	)-	_	PUNCT	_	_	_	_	_	_
16	J	_	PROPN	_	Number=Sing	_	_	_	_
17	recombinase	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	fusion	_	NOUN	_	Number=Sing	_	_	_	_
3	complementary	_	ADJ	_	Degree=Pos	_	_	_	_
4	DNA	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	line	_	NOUN	_	Number=Sing	_	_	_	_
10	HSB	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	elucidates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	provocative	_	ADJ	_	Degree=Pos	_	_	_	_
16	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	disruption	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	putative	_	ADJ	_	Degree=Pos	_	_	_	_
23	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	SCL	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	fusion	_	NOUN	_	Number=Sing	_	_	_	_
3	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	interstitial	_	ADJ	_	Degree=Pos	_	_	_	_
8	deletion	_	NOUN	_	Number=Sing	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	previously	_	ADV	_	_	_	_	_	_
12	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
13	locus	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	SIL	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	SCL	_	PROPN	_	Number=Sing	_	_	_	_
18	interrupting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	locus	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	5	_	NUM	_	NumType=Card	_	_	_	_
25	'	_	PUNCT	_	_	_	_	_	_
26	untranslated	_	ADJ	_	Degree=Pos	_	_	_	_
27	region	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	SCL	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	1;14	_	NUM	_	NumType=Card	_	_	_	_
4	translocations	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	deletion	_	NOUN	_	Number=Sing	_	_	_	_
8	disrupts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	SCL	_	NOUN	_	Number=Sing	_	_	_	_
11	5	_	NUM	_	NumType=Card	_	_	_	_
12	'	_	PUNCT	_	_	_	_	_	_
13	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	region	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	event	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	probably	_	ADV	_	_	_	_	_	_
5	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	V	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	D	_	X	_	Number=Sing	_	_	_	_
11	)-	_	PUNCT	_	_	_	_	_	_
12	J	_	PROPN	_	Number=Sing	_	_	_	_
13	recombinase	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	although	_	SCONJ	_	_	_	_	_	_
17	neither	_	DET	_	_	_	_	_	_
18	locus	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	immunoglobulin	_	NOUN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	T	_	NOUN	_	NumType=Card	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	lines	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	CEM	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	RPMI	_	PROPN	_	Number=Sing	_	_	_	_
10	8402	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	essentially	_	ADV	_	_	_	_	_	_
14	identical	_	ADJ	_	Degree=Pos	_	_	_	_
15	deletions	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	growth	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	other	_	ADJ	_	Degree=Pos	_	_	_	_
11	than	_	ADP	_	_	_	_	_	_
12	immune	_	ADJ	_	Degree=Pos	_	_	_	_
13	receptors	_	NOUN	_	Number=Plur	_	_	_	_
14	risk	_	NOUN	_	Number=Sing	_	_	_	_
15	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003423	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	10	_	NUM	_	NumType=Card	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	lines	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	10	_	NUM	_	NumType=Card	_	_	_	_
8	inhibit	_	VERB	_	Number=Sing	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	transcriptional	_	ADJ	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	post-transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	6	_	NUM	_	NumType=Card	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	10	_	NUM	_	NumType=Card	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
31	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	6	_	NUM	_	NumType=Card	_	_	_	_
35	production	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	expression	_	NOUN	_	Number=Sing	_	_	_	_
38	level	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	6	_	NUM	_	NumType=Card	_	_	_	_
43	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	IL	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	6	_	NUM	_	NumType=Card	_	_	_	_
48	promoter	_	NOUN	_	Number=Sing	_	_	_	_
49	activity	_	NOUN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
52	activity	_	NOUN	_	Number=Sing	_	_	_	_
53	of	_	ADP	_	_	_	_	_	_
54	NF	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
57	and	_	CCONJ	_	_	_	_	_	_
58	NF	_	PROPN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	IL	_	PROPN	_	Number=Sing	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	6	_	NUM	_	NumType=Card	_	_	_	_
63	,	_	PUNCT	_	_	_	_	_	_
64	and	_	CCONJ	_	_	_	_	_	_
65	IL	_	PROPN	_	Number=Sing	_	_	_	_
66	-	_	PUNCT	_	_	_	_	_	_
67	6	_	NUM	_	NumType=Card	_	_	_	_
68	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
69	stability	_	NOUN	_	Number=Sing	_	_	_	_
70	in	_	ADP	_	_	_	_	_	_
71	human	_	ADJ	_	Degree=Pos	_	_	_	_
72	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
73	cell	_	NOUN	_	Number=Sing	_	_	_	_
74	lines	_	NOUN	_	Number=Plur	_	_	_	_
75	,	_	PUNCT	_	_	_	_	_	_
76	THP	_	NOUN	_	Number=Sing	_	_	_	_
77	-	_	PUNCT	_	_	_	_	_	_
78	1	_	NUM	_	NumType=Card	_	_	_	_
79	and	_	CCONJ	_	_	_	_	_	_
80	U937	_	NOUN	_	Number=Sing	_	_	_	_
81	,	_	PUNCT	_	_	_	_	_	_
82	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
83	by	_	ADP	_	_	_	_	_	_
84	PMA	_	PROPN	_	Number=Sing	_	_	_	_
85	and	_	CCONJ	_	_	_	_	_	_
86	LPS	_	NOUN	_	Number=Plur	_	_	_	_
87	in	_	ADP	_	_	_	_	_	_
88	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
89	absence	_	NOUN	_	Number=Sing	_	_	_	_
90	or	_	CCONJ	_	_	_	_	_	_
91	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
92	presence	_	NOUN	_	Number=Sing	_	_	_	_
93	of	_	ADP	_	_	_	_	_	_
94	IL	_	PROPN	_	Number=Sing	_	_	_	_
95	-	_	PUNCT	_	_	_	_	_	_
96	4	_	NUM	_	NumType=Card	_	_	_	_
97	or	_	CCONJ	_	_	_	_	_	_
98	IL	_	PROPN	_	Number=Sing	_	_	_	_
99	-	_	PUNCT	_	_	_	_	_	_
100	10	_	NUM	_	NumType=Card	_	_	_	_
101	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	4	_	NUM	_	NumType=Card	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	10	_	NUM	_	NumType=Card	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	6	_	NUM	_	NumType=Card	_	_	_	_
24	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	both	_	DET	_	_	_	_	_	_
27	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	lines	_	NOUN	_	Number=Plur	_	_	_	_
30	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
3	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	utilizing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transient	_	ADJ	_	Degree=Pos	_	_	_	_
9	transfection	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
13	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
14	reporter	_	NOUN	_	Number=Sing	_	_	_	_
15	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
16	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	6	_	NUM	_	NumType=Card	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	4	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	but	_	CCONJ	_	_	_	_	_	_
29	not	_	ADV	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	10	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	suppressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
37	activity	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	6	_	NUM	_	NumType=Card	_	_	_	_
43	gene	_	NOUN	_	Number=Sing	_	_	_	_
44	promoter	_	NOUN	_	Number=Sing	_	_	_	_
45	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	by	_	ADP	_	_	_	_	_	_
47	PMA	_	PROPN	_	Number=Sing	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	LPS	_	PROPN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	4	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	ADV	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	10	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	NF	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	4	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	10	_	NUM	_	NumType=Card	_	_	_	_
33	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	IL	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	6	_	NUM	_	NumType=Card	_	_	_	_
41	activity	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	hand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	10	_	NUM	_	NumType=Card	_	_	_	_
9	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	degradation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
20	stability	_	NOUN	_	Number=Sing	_	_	_	_
21	assay	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	6	_	NUM	_	NumType=Card	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	SCONJ	_	_	_	_	_	_
19	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	while	_	SCONJ	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	10	_	NUM	_	NumType=Card	_	_	_	_
30	may	_	AUX	_	VerbForm=Fin	_	_	_	_
31	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	6	_	NUM	_	NumType=Card	_	_	_	_
36	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
37	levels	_	NOUN	_	Number=Plur	_	_	_	_
38	post	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	transcriptionally	_	ADV	_	_	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	without	_	SCONJ	_	_	_	_	_	_
43	suppressing	_	VERB	_	VerbForm=Ger	_	_	_	_
44	promoter	_	NOUN	_	Number=Sing	_	_	_	_
45	activity	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	10	_	NUM	_	NumType=Card	_	_	_	_
13	inhibit	_	VERB	_	Number=Sing	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	6	_	NUM	_	NumType=Card	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	different	_	ADJ	_	Degree=Pos	_	_	_	_
20	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	lines	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003424	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Flutamide	_	NOUN	_	Number=Sing	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	hirsutism	_	NOUN	_	Number=Sing	_	_	_	_
7	:	_	PUNCT	_	_	_	_	_	_
8	long	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	term	_	NOUN	_	Number=Sing	_	_	_	_
11	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
12	effects	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	endocrine	_	NOUN	_	Number=Sing	_	_	_	_
15	changes	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	androgen	_	ADJ	_	Degree=Pos	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	behavior	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	OBJECTIVE	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	long	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	term	_	NOUN	_	Number=Sing	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	treatment	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	low	_	ADJ	_	Degree=Pos	_	_	_	_
12	doses	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	flutamide	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	hormonal	_	ADJ	_	Degree=Pos	_	_	_	_
19	parameters	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	as	_	ADV	_	_	_	_	_	_
22	well	_	ADV	_	Degree=Pos	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	androgen	_	NOUN	_	Degree=Pos	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	status	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	hirsute	_	ADJ	_	Degree=Pos	_	_	_	_
32	women	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	DESIGN	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Eighteen	_	NUM	_	NumType=Card	_	_	_	_
4	hirsute	_	ADJ	_	Degree=Pos	_	_	_	_
5	patients	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	regular	_	ADJ	_	Degree=Pos	_	_	_	_
8	menses	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	basally	_	ADV	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	during	_	ADP	_	_	_	_	_	_
14	treatment	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	125	_	NUM	_	NumType=Card	_	_	_	_
17	mg	_	NUM	_	Number=Sing	_	_	_	_
18	flutamide	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	three	_	NUM	_	NumType=Card	_	_	_	_
21	times	_	NOUN	_	Number=Plur	_	_	_	_
22	per	_	ADP	_	_	_	_	_	_
23	day	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	12	_	NUM	_	NumType=Card	_	_	_	_
26	months	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Barrier	_	NOUN	_	Number=Sing	_	_	_	_
2	or	_	CCONJ	_	_	_	_	_	_
3	intrauterine	_	ADJ	_	Number=Sing	_	_	_	_
4	contraception	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	during	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	study	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	sexually	_	ADV	_	_	_	_	_	_
12	active	_	ADJ	_	Degree=Pos	_	_	_	_
13	women	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Safety	_	NOUN	_	Number=Sing	_	_	_	_
2	parameters	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	throughout	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	study	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Hirsutism	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	graded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	Ferriman	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Gallwey	_	PROPN	_	Number=Sing	_	_	_	_
10	score	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	hormonal	_	ADJ	_	Degree=Pos	_	_	_	_
14	parameters	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	basally	_	ADV	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	at	_	ADP	_	_	_	_	_	_
20	4	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	month	_	NOUN	_	Number=Sing	_	_	_	_
23	intervals	_	NOUN	_	Number=Plur	_	_	_	_
24	during	_	ADP	_	_	_	_	_	_
25	treatment	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Gonadotropin	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	releasing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	hormone	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	ACTH	_	NOUN	_	Number=Sing	_	_	_	_
7	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
8	tests	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	before	_	ADV	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	after	_	ADP	_	_	_	_	_	_
14	3	_	NUM	_	NumType=Card	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	months	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	therapy	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	concentration	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	androgen	_	ADJ	_	Degree=Pos	_	_	_	_
8	receptors	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	both	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	follicular	_	NOUN	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	luteal	_	ADJ	_	Degree=Pos	_	_	_	_
21	phases	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	menstrual	_	ADJ	_	Degree=Pos	_	_	_	_
25	cycle	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	basally	_	ADV	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	after	_	ADP	_	_	_	_	_	_
30	4	_	NUM	_	NumType=Card	_	_	_	_
31	months	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	flutamide	_	ADJ	_	Degree=Pos	_	_	_	_
34	treatment	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Flutamide	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	well	_	ADV	_	Degree=Pos	_	_	_	_
6	tolerated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	all	_	DET	_	_	_	_	_	_
9	women	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	noticeable	_	ADJ	_	Degree=Pos	_	_	_	_
14	exception	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	one	_	NUM	_	NumType=Card	_	_	_	_
17	patient	_	NOUN	_	Number=Sing	_	_	_	_
18	who	_	PRON	_	PronType=Rel	_	_	_	_
19	presented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	serum	_	NOUN	_	Number=Sing	_	_	_	_
22	transaminase	_	NOUN	_	Number=Sing	_	_	_	_
23	after	_	ADP	_	_	_	_	_	_
24	8	_	NUM	_	NumType=Card	_	_	_	_
25	months	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	therapy	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Hirsutism	_	NOUN	_	Number=Sing	_	_	_	_
2	markedly	_	ADV	_	_	_	_	_	_
3	improved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	all	_	DET	_	_	_	_	_	_
6	women	_	NOUN	_	Number=Plur	_	_	_	_
7	during	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	treatment	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	Ferriman	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	Gallwey	_	PROPN	_	Number=Sing	_	_	_	_
14	score	_	NOUN	_	Number=Sing	_	_	_	_
15	after	_	ADP	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	year	_	NOUN	_	Number=Sing	_	_	_	_
18	:	_	PUNCT	_	_	_	_	_	_
19	4.1	_	NUM	_	NumType=Card	_	_	_	_
20	+/-	_	SYM	_	_	_	_	_	_
21	0.5	_	NUM	_	NumType=Card	_	_	_	_
22	versus	_	ADP	_	_	_	_	_	_
23	14.1	_	NUM	_	NumType=Card	_	_	_	_
24	+/-	_	SYM	_	_	_	_	_	_
25	0.9	_	NUM	_	NumType=Card	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	reduction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	serum	_	NOUN	_	Number=Sing	_	_	_	_
5	androgens	_	NOUN	_	Number=Plur	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	whereas	_	SCONJ	_	_	_	_	_	_
10	no	_	DET	_	_	_	_	_	_
11	change	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	either	_	CCONJ	_	_	_	_	_	_
16	basal	_	NOUN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	GnRH	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	gonadotropins	_	NOUN	_	Number=Plur	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	17	_	NUM	_	NumType=Card	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	hydroxyprogesterone	_	NOUN	_	Number=Sing	_	_	_	_
31	response	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	ACTH	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Cycles	_	NOUN	_	Number=Plur	_	_	_	_
2	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	ovulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Before	_	ADP	_	_	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	number	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	androgen	_	ADJ	_	Degree=Pos	_	_	_	_
8	receptors	_	NOUN	_	Number=Plur	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	luteal	_	NOUN	_	Number=Sing	_	_	_	_
14	than	_	ADP	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
18	phase	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	rhythmic	_	ADJ	_	Degree=Pos	_	_	_	_
3	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
4	disappeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	after	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	patients	_	NOUN	_	Number=Plur	_	_	_	_
8	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	given	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	antiandrogen	_	NOUN	_	Degree=Pos	_	_	_	_
13	drug	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Flutamide	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	effective	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	treatment	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	hirsutism	_	NOUN	_	Number=Sing	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	constant	_	ADJ	_	Degree=Pos	_	_	_	_
14	surveillance	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	liver	_	NOUN	_	Number=Sing	_	_	_	_
17	function	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Androgen	_	NOUN	_	Degree=Pos	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	blockade	_	NOUN	_	Number=Sing	_	_	_	_
4	might	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	potentiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	reduction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	serum	_	NOUN	_	Number=Sing	_	_	_	_
12	androgens	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Flutamide	_	ADJ	_	Number=Sing	_	_	_	_
2	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	androgen	_	NOUN	_	Degree=Pos	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	behavior	_	NOUN	_	Number=Sing	_	_	_	_
6	during	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	menstrual	_	ADJ	_	Degree=Pos	_	_	_	_
9	cycle	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	meaning	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	finding	_	NOUN	_	Number=Sing	_	_	_	_
6	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	elucidated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003430	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	E1A	_	PROPN	_	Number=Sing	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	susceptibility	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	SCONJ	_	_	_	_	_	_
7	killing	_	VERB	_	VerbForm=Ger	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	NK	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	following	_	VERB	_	VerbForm=Ger	_	_	_	_
12	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	adenovirus	_	ADJ	_	Degree=Pos	_	_	_	_
16	infection	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Adenovirus	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	Ad	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	infection	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	E1A	_	NOUN	_	Number=Sing	_	_	_	_
8	transfection	_	NOUN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	model	_	NOUN	_	Number=Sing	_	_	_	_
13	changes	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	susceptibility	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	NK	_	PROPN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	killing	_	NOUN	_	VerbForm=Ger	_	_	_	_
20	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	transient	_	NOUN	_	Number=Sing	_	_	_	_
23	vs	_	ADP	_	_	_	_	_	_
24	stable	_	ADJ	_	Number=Sing	_	_	_	_
25	E1A	_	PROPN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Only	_	ADV	_	_	_	_	_	_
2	stably	_	ADV	_	_	_	_	_	_
3	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	target	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	exhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	cytolytic	_	ADJ	_	Degree=Pos	_	_	_	_
8	susceptibility	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	despite	_	ADP	_	_	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	equivalent	_	ADJ	_	Degree=Pos	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	E1A	_	NOUN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	Ad	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	targets	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	E1A	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	products	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
9	cytolytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	susceptibility	_	NOUN	_	Number=Sing	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	infection	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	explained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
19	effect	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	viral	_	ADJ	_	Degree=Pos	_	_	_	_
22	infection	_	NOUN	_	Number=Sing	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	otherwise	_	ADV	_	_	_	_	_	_
25	susceptible	_	ADJ	_	Degree=Pos	_	_	_	_
26	target	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	viral	_	ADJ	_	Degree=Pos	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	effects	_	NOUN	_	Number=Plur	_	_	_	_
33	on	_	ADP	_	_	_	_	_	_
34	class	_	NOUN	_	Number=Sing	_	_	_	_
35	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
36	MHC	_	PROPN	_	Number=Sing	_	_	_	_
37	antigen	_	NOUN	_	Degree=Pos	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	on	_	ADP	_	_	_	_	_	_
40	target	_	NOUN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	differential	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	E1A	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	cytolytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	phenotypes	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	infected	_	VERB	_	Degree=Pos	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	stably	_	ADV	_	_	_	_	_	_
15	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	NK	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	effective	_	ADJ	_	Degree=Pos	_	_	_	_
26	immunologic	_	ADJ	_	Degree=Pos	_	_	_	_
27	barrier	_	NOUN	_	Number=Sing	_	_	_	_
28	against	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	vivo	_	ADJ	_	Degree=Pos	_	_	_	_
32	survival	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	neoplastic	_	ADJ	_	Degree=Pos	_	_	_	_
35	progression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	E1A	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	immortalized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	that	_	PRON	_	PronType=Rel	_	_	_	_
42	may	_	AUX	_	VerbForm=Fin	_	_	_	_
43	emerge	_	VERB	_	VerbForm=Inf	_	_	_	_
44	from	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	reservoir	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	persistently	_	ADV	_	_	_	_	_	_
49	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	cells	_	NOUN	_	Number=Plur	_	_	_	_
51	in	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	human	_	ADJ	_	Degree=Pos	_	_	_	_
54	host	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003434	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	lines	_	NOUN	_	Number=Plur	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	redox	_	NOUN	_	Number=Sing	_	_	_	_
12	changes	_	NOUN	_	Number=Plur	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
16	depletion	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	redox	_	NOUN	_	Number=Sing	_	_	_	_
8	changes	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vivo	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	HL	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	60	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	KG	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	depleting	_	VERB	_	VerbForm=Ger	_	_	_	_
5	agent	_	NOUN	_	Number=Sing	_	_	_	_
6	diethyl	_	NOUN	_	Number=Sing	_	_	_	_
7	maleate	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	DEM	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	development	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	differentiated	_	ADJ	_	Degree=Pos	_	_	_	_
16	features	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
21	esters	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	including	_	VERB	_	VerbForm=Ger	_	_	_	_
24	adherence	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	plastic	_	ADJ	_	Degree=Pos	_	_	_	_
30	surfaces	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	repression	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	myeloperoxidase	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	CD34	_	PROPN	_	Number=Sing	_	_	_	_
38	genes	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	DEM	_	PROPN	_	Number=Sing	_	_	_	_
4	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
6	12	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	myristate	_	VERB	_	Number=Sing	_	_	_	_
9	13	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	acetate	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	AP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	Egr	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
32	may	_	AUX	_	VerbForm=Fin	_	_	_	_
33	be	_	AUX	_	VerbForm=Inf	_	_	_	_
34	due	_	ADP	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	at	_	ADV	_	_	_	_	_	_
37	least	_	ADV	_	Degree=Sup	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	part	_	ADJ	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	redox	_	VERB	_	VerbForm=Inf	_	_	_	_
43	modifications	_	NOUN	_	Number=Plur	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
46	proteins	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003436	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	new	_	ADJ	_	Degree=Pos	_	_	_	_
3	member	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	leucine	_	NOUN	_	Number=Sing	_	_	_	_
7	zipper	_	NOUN	_	Number=Sing	_	_	_	_
8	class	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	HLA	_	PROPN	_	Number=Sing	_	_	_	_
16	DR	_	NOUN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	mutants	_	NOUN	_	Number=Plur	_	_	_	_
3	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	lines	_	NOUN	_	Number=Plur	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	defective	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	SCONJ	_	_	_	_	_	_
13	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	major	_	ADJ	_	Degree=Pos	_	_	_	_
15	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
16	complex	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	MHC	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	class	_	NOUN	_	Number=Sing	_	_	_	_
21	II	_	NUM	_	Number=Sing	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	failure	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	express	_	VERB	_	VerbForm=Inf	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	class	_	NOUN	_	Number=Sing	_	_	_	_
7	II	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	at	_	ADV	_	_	_	_	_	_
11	least	_	ADV	_	Degree=Sup	_	_	_	_
12	one	_	NUM	_	NumType=Card	_	_	_	_
13	such	_	ADJ	_	Degree=Pos	_	_	_	_
14	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
15	line	_	NOUN	_	Number=Sing	_	_	_	_
16	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
18	mapped	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	MHC	_	PROPN	_	Number=Sing	_	_	_	_
22	class	_	NOUN	_	Number=Sing	_	_	_	_
23	II	_	NUM	_	Number=Sing	_	_	_	_
24	X	_	PROPN	_	_	_	_	_	_
25	box	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	conserved	_	VERB	_	Degree=Pos	_	_	_	_
29	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
30	element	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	region	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	complementary	_	ADJ	_	Degree=Pos	_	_	_	_
3	DNA	_	NOUN	_	Number=Sing	_	_	_	_
4	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	DNA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	X	_	NOUN	_	_	_	_	_	_
13	box	_	NOUN	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	hXBP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
22	target	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	DR	_	NOUN	_	Number=Sing	_	_	_	_
27	alpha	_	PROPN	_	Number=Sing	_	_	_	_
28	X	_	PROPN	_	_	_	_	_	_
29	box	_	PROPN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	3	_	NUM	_	NumType=Card	_	_	_	_
33	'	_	PUNCT	_	_	_	_	_	_
34	flanking	_	NOUN	_	Number=Sing	_	_	_	_
35	region	_	NOUN	_	Number=Sing	_	_	_	_
36	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	now	_	ADV	_	_	_	_	_	_
38	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
39	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	complementary	_	ADJ	_	Degree=Pos	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	encoded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	structural	_	ADJ	_	Degree=Pos	_	_	_	_
9	similarities	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
13	proto	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
16	product	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	target	_	NOUN	_	Number=Sing	_	_	_	_
21	sequence	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	closely	_	ADV	_	_	_	_	_	_
24	related	_	ADJ	_	Degree=Pos	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	palindromic	_	ADJ	_	Degree=Pos	_	_	_	_
28	target	_	NOUN	_	Number=Sing	_	_	_	_
29	sequence	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	hXBP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	DNA	_	NOUN	_	Number=Sing	_	_	_	_
8	target	_	NOUN	_	Number=Sing	_	_	_	_
9	sequence	_	NOUN	_	Number=Sing	_	_	_	_
10	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	DR	_	NOUN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	vivo	_	PROPN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	hXBP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	B	_	ADJ	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003437	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	VERB	_	VerbForm=Ger	_	_	_	_
2	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
9	blood	_	NOUN	_	Number=Sing	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
13	sclerosis	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	exact	_	ADJ	_	Degree=Pos	_	_	_	_
4	etiology	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
7	sclerosis	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	MS	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	unresolved	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	immune	_	ADJ	_	Degree=Pos	_	_	_	_
15	reactions	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	central	_	ADJ	_	Degree=Pos	_	_	_	_
22	pathogenic	_	ADJ	_	Number=Sing	_	_	_	_
23	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
4	steroid	_	NOUN	_	Number=Sing	_	_	_	_
5	hormones	_	NOUN	_	Number=Plur	_	_	_	_
6	affect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	immune	_	NOUN	_	Number=Sing	_	_	_	_
9	system	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	diseases	_	NOUN	_	Number=Plur	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	hypothalamic	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	adrenal	_	ADJ	_	Degree=Pos	_	_	_	_
25	axis	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	providing	_	VERB	_	VerbForm=Ger	_	_	_	_
28	evidence	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	immune	_	ADJ	_	Degree=Pos	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	endocrine	_	NOUN	_	Degree=Pos	_	_	_	_
34	interplay	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Function	_	NOUN	_	Number=Sing	_	_	_	_
2	tests	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	MS	_	PROPN	_	Number=Sing	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	dysregulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	hypothalamic	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	adrenal	_	ADJ	_	Degree=Pos	_	_	_	_
15	system	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
19	proportion	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	patients	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	characterized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	GR	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
11	blood	_	NOUN	_	Number=Sing	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	39	_	NUM	_	NumType=Card	_	_	_	_
15	MS	_	PROPN	_	Number=Sing	_	_	_	_
16	patients	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	14	_	NUM	_	NumType=Card	_	_	_	_
19	age	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	sex	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	matched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	controls	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	respect	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
30	constant	_	ADJ	_	Degree=Pos	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	capacity	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	using	_	VERB	_	VerbForm=Ger	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	whole	_	ADJ	_	Degree=Pos	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	binding	_	NOUN	_	Number=Sing	_	_	_	_
41	assay	_	NOUN	_	Number=Sing	_	_	_	_
42	with	_	ADP	_	_	_	_	_	_
43	[	_	PUNCT	_	_	_	_	_	_
44	3	_	NUM	_	NumType=Card	_	_	_	_
45	H	_	NOUN	_	Number=Sing	_	_	_	_
46	]	_	PUNCT	_	_	_	_	_	_
47	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
48	as	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	ligand	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	GR	_	NOUN	_	Number=Sing	_	_	_	_
2	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
3	parameters	_	NOUN	_	Number=Plur	_	_	_	_
4	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	differ	_	VERB	_	VerbForm=Inf	_	_	_	_
7	significantly	_	ADV	_	_	_	_	_	_
8	between	_	ADP	_	_	_	_	_	_
9	patients	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	Kd	_	NOUN	_	Number=Sing	_	_	_	_
12	8.98	_	NUM	_	NumType=Card	_	_	_	_
13	+/-	_	SYM	_	_	_	_	_	_
14	1.07	_	NUM	_	NumType=Card	_	_	_	_
15	nM	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	Bmax	_	NOUN	_	Number=Sing	_	_	_	_
18	183	_	NUM	_	NumType=Card	_	_	_	_
19	+/-	_	SYM	_	_	_	_	_	_
20	29.8	_	NUM	_	NumType=Card	_	_	_	_
21	fmol	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	SYM	_	_	_	_	_	_
23	mg	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	controls	_	NOUN	_	Number=Plur	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	Kd	_	NOUN	_	Number=Sing	_	_	_	_
29	9.36	_	NUM	_	NumType=Card	_	_	_	_
30	+/-	_	SYM	_	_	_	_	_	_
31	1.17	_	NUM	_	NumType=Card	_	_	_	_
32	nM	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	Bmax	_	NOUN	_	Number=Sing	_	_	_	_
35	158	_	NUM	_	NumType=Card	_	_	_	_
36	+/-	_	SYM	_	_	_	_	_	_
37	16	_	NUM	_	NumType=Card	_	_	_	_
38	fmol	_	NOUN	_	Number=Sing	_	_	_	_
39	/	_	SYM	_	_	_	_	_	_
40	mg	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	age	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	sex	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	course	_	NOUN	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	duration	_	NOUN	_	Number=Sing	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	severity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	disease	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	prior	_	ADJ	_	Degree=Pos	_	_	_	_
18	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
19	treatments	_	NOUN	_	Number=Plur	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	GR	_	NOUN	_	Number=Sing	_	_	_	_
2	binding	_	VERB	_	Number=Sing	_	_	_	_
3	parameters	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	relation	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	results	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	CRH	_	NOUN	_	Number=Sing	_	_	_	_
17	test	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	reflects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	corticosteroid	_	NOUN	_	Degree=Pos	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	function	_	NOUN	_	Number=Sing	_	_	_	_
24	at	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	hypothalamus	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	30	_	NUM	_	NumType=Card	_	_	_	_
30	patients	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	9	_	NUM	_	NumType=Card	_	_	_	_
33	controls	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	controls	_	NOUN	_	Number=Plur	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	moderate	_	ADJ	_	Degree=Pos	_	_	_	_
6	correlation	_	NOUN	_	Number=Sing	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
9	affinity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	GR	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	function	_	NOUN	_	Number=Sing	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	hypothalamic	_	ADJ	_	Degree=Pos	_	_	_	_
21	level	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	patients	_	NOUN	_	Number=Plur	_	_	_	_
25	did	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
7	relationship	_	NOUN	_	Number=Sing	_	_	_	_
8	between	_	ADP	_	_	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	function	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	disturbed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	MS	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003438	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
5	action	_	NOUN	_	Number=Sing	_	_	_	_
6	:	_	PUNCT	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	novel	_	NOUN	_	Number=Sing	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cross	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	talk	_	NOUN	_	Number=Sing	_	_	_	_
14	between	_	ADP	_	_	_	_	_	_
15	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	NF	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Despite	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	widespread	_	ADJ	_	Degree=Pos	_	_	_	_
4	use	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	treatment	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	diseases	_	NOUN	_	Number=Plur	_	_	_	_
12	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
18	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	s	_	X	_	_	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
25	hormones	_	NOUN	_	Number=Plur	_	_	_	_
26	exert	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	beneficial	_	ADJ	_	Degree=Pos	_	_	_	_
29	effect	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	patients	_	NOUN	_	Number=Sing	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	asthma	_	NOUN	_	Number=Sing	_	_	_	_
34	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	be	_	AUX	_	VerbForm=Inf	_	_	_	_
37	elucidated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
12	molecule	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
22	molecules	_	NOUN	_	Number=Plur	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	likely	_	ADJ	_	Degree=Pos	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	play	_	VERB	_	VerbForm=Inf	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	causal	_	ADJ	_	Degree=Pos	_	_	_	_
29	role	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	SCONJ	_	_	_	_	_	_
33	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	matrix	_	NOUN	_	Number=Sing	_	_	_	_
41	interactions	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	monocytic	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	U937	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	bronchial	_	ADJ	_	Degree=Pos	_	_	_	_
13	epithelial	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	H292	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	line	_	NOUN	_	Number=Sing	_	_	_	_
20	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
21	strongly	_	ADV	_	_	_	_	_	_
22	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	basal	_	ADJ	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	both	_	DET	_	_	_	_	_	_
14	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
15	13	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	acetate	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	TPA	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	tumour	_	NOUN	_	Number=Sing	_	_	_	_
23	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	TNF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	upregulate	_	VERB	_	Degree=Pos	_	_	_	_
33	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	through	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	presence	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
43	factor	_	NOUN	_	Number=Sing	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	NF	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	kappa	_	NOUN	_	Number=Sing	_	_	_	_
48	B	_	NOUN	_	_	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	target	_	NOUN	_	Number=Sing	_	_	_	_
51	sequence	_	NOUN	_	Number=Sing	_	_	_	_
52	(	_	PUNCT	_	_	_	_	_	_
53	TGGAAATTCC	_	PROPN	_	Number=Sing	_	_	_	_
54	)	_	PUNCT	_	_	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
3	recognition	_	NOUN	_	Number=Sing	_	_	_	_
4	sequences	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	present	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	region	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	still	_	ADV	_	_	_	_	_	_
15	able	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	repress	_	VERB	_	VerbForm=Inf	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	when	_	ADV	_	PronType=Int	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	multimerized	_	ADJ	_	Degree=Pos	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	sequence	_	NOUN	_	Number=Sing	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	transactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	TNF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	alpha	_	NOUN	_	Number=Sing	_	_	_	_
33	upon	_	ADP	_	_	_	_	_	_
34	transfection	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	293	_	NUM	_	NumType=Card	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	DET	_	_	_	_	_	_
4	direct	_	ADJ	_	Degree=Pos	_	_	_	_
5	interaction	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	at	_	ADV	_	_	_	_	_	_
19	least	_	ADV	_	Degree=Sup	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	partial	_	ADJ	_	Degree=Pos	_	_	_	_
22	explanation	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	effects	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	hormone	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	diseases	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003442	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Barr	_	PROPN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	antigen	_	NOUN	_	Number=Sing	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	transactivates	_	NOUN	_	Number=Plur	_	_	_	_
9	latent	_	ADJ	_	Degree=Pos	_	_	_	_
10	membrane	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	lines	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	evidence	_	NOUN	_	Number=Sing	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	compatible	_	ADJ	_	Degree=Pos	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	SCONJ	_	PronType=Rel	_	_	_	_
11	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	Barr	_	PROPN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	EBV	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	antigen	_	NOUN	_	Number=Sing	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	leader	_	NOUN	_	Number=Sing	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	LP	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	EBV	_	PROPN	_	Number=Sing	_	_	_	_
39	latent	_	ADJ	_	Degree=Pos	_	_	_	_
40	infection	_	NOUN	_	Number=Sing	_	_	_	_
41	membrane	_	NOUN	_	Number=Sing	_	_	_	_
42	protein	_	NOUN	_	Number=Sing	_	_	_	_
43	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	following	_	VERB	_	VerbForm=Ger	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	i	_	X	_	_	_	_	_	_
3	)	_	PUNCT	_	_	_	_	_	_
4	Acute	_	ADJ	_	Degree=Pos	_	_	_	_
5	transfection	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	under	_	ADP	_	_	_	_	_	_
13	control	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	simian	_	ADJ	_	Degree=Pos	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	40	_	NUM	_	NumType=Card	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	Moloney	_	PROPN	_	Number=Sing	_	_	_	_
20	murine	_	NOUN	_	Number=Sing	_	_	_	_
21	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
22	virus	_	NOUN	_	Number=Sing	_	_	_	_
23	promoters	_	NOUN	_	Number=Plur	_	_	_	_
24	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	P3HR	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1-infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	Burkitt	_	PROPN	_	Number=Sing	_	_	_	_
34	's	_	PART	_	_	_	_	_	_
35	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	P3HR	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	or	_	CCONJ	_	_	_	_	_	_
43	Daudi	_	PROPN	_	Number=Sing	_	_	_	_
44	cell	_	NOUN	_	Number=Sing	_	_	_	_
45	line	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ii	_	X	_	_	_	_	_	_
3	)	_	PUNCT	_	_	_	_	_	_
4	Transfection	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	LP	_	PROPN	_	Number=Sing	_	_	_	_
11	alone	_	ADV	_	_	_	_	_	_
12	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	no	_	DET	_	_	_	_	_	_
14	effect	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	act	_	VERB	_	VerbForm=Inf	_	_	_	_
22	synergistically	_	ADV	_	_	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
29	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	iii	_	X	_	_	_	_	_	_
3	)	_	PUNCT	_	_	_	_	_	_
4	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	Daudi	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	P3HR	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	Daudi	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
32	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	i	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	v	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	No	_	DET	_	_	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	EBV	_	PROPN	_	Number=Sing	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
18	since	_	ADP	_	_	_	_	_	_
19	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
22	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	vectors	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
29	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
30	DNA	_	PROPN	_	Number=Sing	_	_	_	_
31	fragments	_	NOUN	_	Number=Plur	_	_	_	_
32	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	EBV	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	negative	_	ADJ	_	Degree=Pos	_	_	_	_
40	B	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
43	cell	_	NOUN	_	Number=Sing	_	_	_	_
44	lines	_	NOUN	_	Number=Plur	_	_	_	_
45	BJAB	_	PROPN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	Louckes	_	PROPN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	BL30	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_
52	(	_	PUNCT	_	_	_	_	_	_
53	v)	_	SYM	_	_	_	_	_	_
54	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
55	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	2	_	NUM	_	NumType=Card	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
60	element	_	NOUN	_	Number=Sing	_	_	_	_
61	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
62	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
63	within	_	ADP	_	_	_	_	_	_
64	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
65	-	_	SYM	_	_	_	_	_	_
66	512	_	NUM	_	NumType=Card	_	_	_	_
67	to	_	ADP	_	_	_	_	_	_
68	+40	_	NUM	_	NumType=Card	_	_	_	_
69	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
70	DNA	_	NOUN	_	Number=Sing	_	_	_	_
71	since	_	SCONJ	_	_	_	_	_	_
72	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
73	DNA	_	PROPN	_	Number=Sing	_	_	_	_
74	linked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
75	to	_	ADP	_	_	_	_	_	_
76	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
77	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
78	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
79	reporter	_	NOUN	_	Number=Sing	_	_	_	_
80	gene	_	NOUN	_	Number=Sing	_	_	_	_
81	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
82	transactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
83	by	_	ADP	_	_	_	_	_	_
84	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
85	with	_	ADP	_	_	_	_	_	_
86	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
87	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
88	-	_	PUNCT	_	_	_	_	_	_
89	2	_	NUM	_	NumType=Card	_	_	_	_
90	expression	_	NOUN	_	Number=Sing	_	_	_	_
91	vector	_	NOUN	_	Number=Sing	_	_	_	_
92	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	vi	_	X	_	Number=Sing	_	_	_	_
3	)	_	PUNCT	_	_	_	_	_	_
4	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	EBV	_	PROPN	_	Number=Sing	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	transactivated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
13	as	_	ADV	_	_	_	_	_	_
14	well	_	ADV	_	Degree=Pos	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	EBV	_	PROPN	_	Number=Sing	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2.	_	NUM	_	NumType=Card	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	vii	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	deletions	_	NOUN	_	Number=Plur	_	_	_	_
3	within	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	rendered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	EBV	_	PROPN	_	Number=Sing	_	_	_	_
12	transformation	_	NOUN	_	Number=Sing	_	_	_	_
13	incompetent	_	ADJ	_	Degree=Pos	_	_	_	_
14	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	whereas	_	SCONJ	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	transformation	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	competent	_	ADJ	_	Degree=Pos	_	_	_	_
24	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	deletion	_	NOUN	_	Number=Sing	_	_	_	_
28	mutant	_	NOUN	_	Number=Sing	_	_	_	_
29	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
31	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	potent	_	ADJ	_	Degree=Pos	_	_	_	_
5	effector	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	lymphocyte	_	NOUN	_	Degree=Pos	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	act	_	VERB	_	VerbForm=Inf	_	_	_	_
14	synergistically	_	ADV	_	_	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
21	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	CD23	_	PROPN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
9	amplifies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	biological	_	ADJ	_	Degree=Pos	_	_	_	_
12	impact	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	underscores	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	central	_	ADJ	_	Degree=Pos	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	EBV	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	growth	_	NOUN	_	Number=Sing	_	_	_	_
27	transformation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003446	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Microtubules	_	NOUN	_	Number=Plur	_	_	_	_
2	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
4	25	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	hydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_

1	D3	_	PROPN	_	Number=Sing	_	_	_	_
2	trafficking	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	1,25	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
11	D3	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	normal	_	ADJ	_	Degree=Pos	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
3	actions	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	1,25	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
8	D3	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	1,25	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	OH	_	NOUN	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	2D3	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
21	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
22	D	_	NOUN	_	Number=Sing	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	VDR	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	immunocytochemistry	_	PROPN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	DET	_	_	_	_	_	_
6	disruption	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	microtubular	_	ADJ	_	Degree=Pos	_	_	_	_
9	assembly	_	NOUN	_	Number=Sing	_	_	_	_
10	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	access	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	sterol	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	VDR	_	NOUN	_	Number=Sing	_	_	_	_
18	complex	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	microtubules	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	response	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	1,25	_	NUM	_	NumType=Card	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	OH	_	INTJ	_	_	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	2D3	_	NUM	_	Number=Sing	_	_	_	_
33	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
36	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	viable	_	ADJ	_	Degree=Pos	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	interaction	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	normal	_	ADJ	_	Degree=Pos	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Monocytes	_	NOUN	_	Number=Sing	_	_	_	_
2	convert	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	25	_	NUM	_	NumType=Card	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	OH	_	INTJ	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	D3	_	NUM	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	1,25	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	OH	_	INTJ	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	2D3	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	24	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	hydroxylated	_	ADJ	_	Degree=Pos	_	_	_	_
19	metabolites	_	NOUN	_	Number=Plur	_	_	_	_
20	more	_	ADJ	_	Degree=Cmp	_	_	_	_
21	polar	_	ADJ	_	Degree=Pos	_	_	_	_
22	than	_	ADP	_	_	_	_	_	_
23	1,25	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	OH	_	INTJ	_	_	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	2D3	_	NUM	_	NumType=Card	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Microtubule	_	NOUN	_	Number=Sing	_	_	_	_
2	disruption	_	NOUN	_	Number=Sing	_	_	_	_
3	totally	_	ADV	_	_	_	_	_	_
4	abolished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	ability	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
9	1,25	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	OH	_	INTJ	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	2D3	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
16	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	own	_	ADJ	_	Degree=Pos	_	_	_	_
18	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
22	24	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	hydroxylase	_	NOUN	_	Number=Sing	_	_	_	_
25	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	without	_	SCONJ	_	_	_	_	_	_
30	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
31	either	_	CCONJ	_	_	_	_	_	_
32	total	_	ADJ	_	Degree=Pos	_	_	_	_
33	1,25	_	NUM	_	NumType=Card	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	OH	_	NOUN	_	_	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	2D3	_	NUM	_	NumType=Card	_	_	_	_
38	uptake	_	NOUN	_	Number=Sing	_	_	_	_
39	or	_	CCONJ	_	_	_	_	_	_
40	maximal	_	ADJ	_	Number=Sing	_	_	_	_
41	1,25	_	NUM	_	NumType=Card	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	OH	_	INTJ	_	_	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	2D3-VDR	_	NOUN	_	Number=Sing	_	_	_	_
46	binding	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	intact	_	VERB	_	Degree=Pos	_	_	_	_
4	microtubules	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	essential	_	ADJ	_	Degree=Pos	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	1,25	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	OH	_	INTJ	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	2D3	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	modulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	microtubule	_	ADJ	_	Degree=Pos	_	_	_	_
4	disruption	_	NOUN	_	Number=Sing	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
8	1,25	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	OH	_	INTJ	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	2D3	_	NUM	_	NumType=Card	_	_	_	_
13	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	by	_	SCONJ	_	_	_	_	_	_
17	decreasing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	Vmax	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
22	mitochondrial	_	NOUN	_	Number=Sing	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	hydroxylase	_	NOUN	_	Number=Sing	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	through	_	ADP	_	_	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	increase	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	Km	_	PROPN	_	Number=Sing	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	25	_	NUM	_	NumType=Card	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	OH	_	INTJ	_	_	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	2D3	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	25	_	NUM	_	NumType=Card	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	OH	_	INTJ	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	D3	_	PROPN	_	Number=Sing	_	_	_	_
8	transport	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Microtubule	_	NOUN	_	Number=Sing	_	_	_	_
2	disruption	_	NOUN	_	Number=Sing	_	_	_	_
3	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
6	total	_	ADJ	_	Degree=Pos	_	_	_	_
7	cellular	_	NOUN	_	Degree=Pos	_	_	_	_
8	25	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	OH	_	INTJ	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	D3	_	NOUN	_	Number=Sing	_	_	_	_
13	uptake	_	NOUN	_	Number=Sing	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	reduced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	trafficking	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	mitochondria	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	microtubules	_	NOUN	_	Number=Plur	_	_	_	_
4	participate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	25	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	OH	_	INTJ	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	D3	_	NOUN	_	Number=Sing	_	_	_	_
12	transport	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	integrity	_	NOUN	_	Number=Sing	_	_	_	_
17	determines	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	1,25	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	OH	_	INTJ	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	2D3	_	NUM	_	Number=Sing	_	_	_	_
24	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003447	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	interferon	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	gamma	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	also	_	ADV	_	_	_	_	_	_
11	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	II	_	NUM	_	NumType=Card	_	_	_	_
15	interferon	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	important	_	ADJ	_	Degree=Pos	_	_	_	_
20	immunoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
25	effects	_	NOUN	_	Number=Plur	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	development	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	maturation	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	function	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	immune	_	NOUN	_	Number=Sing	_	_	_	_
37	system	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	IFN	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	predominantly	_	ADV	_	_	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	T	_	ADJ	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	large	_	ADJ	_	Degree=Pos	_	_	_	_
15	granular	_	ADJ	_	Degree=Pos	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IFN	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	gamma	_	NOUN	_	Number=Sing	_	_	_	_
5	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	types	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	wide	_	ADJ	_	Degree=Pos	_	_	_	_
17	variety	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
20	signals	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	thus	_	ADV	_	_	_	_	_	_
23	implicating	_	VERB	_	VerbForm=Ger	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	number	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	yet	_	CCONJ	_	_	_	_	_	_
30	convergent	_	ADJ	_	Degree=Pos	_	_	_	_
31	signal	_	NOUN	_	Number=Sing	_	_	_	_
32	transduction	_	NOUN	_	Number=Sing	_	_	_	_
33	pathways	_	NOUN	_	Number=Plur	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
36	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
37	control	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	review	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	how	_	ADV	_	PronType=Int	_	_	_	_
8	DNA	_	PROPN	_	Number=Sing	_	_	_	_
9	methylation	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	IFN	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	gamma	_	NOUN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	response	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
28	signals	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003449	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Signal	_	NOUN	_	Number=Sing	_	_	_	_
2	transduction	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	DR3	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	death	_	NOUN	_	Number=Sing	_	_	_	_
8	domain	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	related	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	TNFR	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	CD95	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	TNFR	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	CD95	_	PROPN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	Fas	_	PROPN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	APO	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	X	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	cytokine	_	VERB	_	Degree=Pos	_	_	_	_
25	receptors	_	NOUN	_	Number=Plur	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	engage	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
30	pathway	_	NOUN	_	Number=Sing	_	_	_	_
31	through	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	region	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
36	homology	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	"	_	PUNCT	_	_	_	_	_	_
41	death	_	NOUN	_	Number=Sing	_	_	_	_
42	domain	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_
44	"	_	PUNCT	_	_	_	_	_	_

1	Another	_	DET	_	_	_	_	_	_
2	death	_	NOUN	_	Number=Sing	_	_	_	_
3	domain	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	member	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	TNFR	_	PROPN	_	Number=Sing	_	_	_	_
10	family	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	death	_	NOUN	_	Number=Sing	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	3	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	DR3	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
26	both	_	CCONJ	_	_	_	_	_	_
27	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	DR3	_	NOUN	_	Number=Sing	_	_	_	_
4	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	tissues	_	NOUN	_	Number=Plur	_	_	_	_
10	enriched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	DR3	_	PROPN	_	Number=Sing	_	_	_	_
2	signal	_	NOUN	_	Number=Sing	_	_	_	_
3	transduction	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	complex	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	signaling	_	NOUN	_	Number=Sing	_	_	_	_
12	molecules	_	NOUN	_	Number=Plur	_	_	_	_
13	including	_	VERB	_	VerbForm=Ger	_	_	_	_
14	TRADD	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	FADD	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	FLICE	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	DR3	_	PROPN	_	Number=Sing	_	_	_	_
4	likely	_	ADV	_	_	_	_	_	_
5	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
10	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	homeostasis	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003452	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	ADJ	_	Number=Sing	_	_	_	_
3	modulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	inhaled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	fluticasone	_	NOUN	_	Number=Sing	_	_	_	_
11	propionate	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	bronchial	_	ADJ	_	Degree=Pos	_	_	_	_
14	mucosa	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	blood	_	NOUN	_	Number=Sing	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	subjects	_	NOUN	_	Number=Plur	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	mild	_	ADJ	_	Degree=Pos	_	_	_	_
22	asthma	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	ADJ	_	Degree=Pos	_	_	_	_
3	regulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	GR	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
13	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	means	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	OBJECTIVE	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	sought	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	vivo	_	ADJ	_	Number=Sing	_	_	_	_
8	modulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	GR	_	NOUN	_	Number=Sing	_	_	_	_
11	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	fluticasone	_	NOUN	_	Number=Sing	_	_	_	_
15	propionate	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	FP	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	subjects	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	mild	_	ADJ	_	Degree=Pos	_	_	_	_
23	asthma	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Ten	_	NUM	_	NumType=Card	_	_	_	_
4	atopic	_	ADJ	_	Degree=Pos	_	_	_	_
5	asthmatic	_	ADJ	_	Degree=Pos	_	_	_	_
6	subjects	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	FP	_	NOUN	_	Number=Sing	_	_	_	_
11	250	_	NUM	_	NumType=Card	_	_	_	_
12	microg	_	NOUN	_	Number=Sing	_	_	_	_
13	twice	_	ADV	_	NumType=Mult	_	_	_	_
14	daily	_	ADV	_	_	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	weeks	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Before	_	ADP	_	_	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	after	_	ADP	_	_	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	patients	_	NOUN	_	Number=Plur	_	_	_	_
8	underwent	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	fiberoptic	_	ADJ	_	Degree=Pos	_	_	_	_
10	bronchoscopy	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	endobronchial	_	ADJ	_	Degree=Pos	_	_	_	_
13	biopsy	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	sampling	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	venous	_	ADJ	_	Degree=Pos	_	_	_	_
18	blood	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	measurements	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	GR	_	NOUN	_	Number=Sing	_	_	_	_
23	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
24	levels	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	solution	_	NOUN	_	Number=Sing	_	_	_	_
3	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	quantitative	_	ADJ	_	Degree=Pos	_	_	_	_
9	analysis	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	GR	_	NOUN	_	Number=Sing	_	_	_	_
12	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	24	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	hour	_	NOUN	_	Number=Sing	_	_	_	_
8	urinary	_	ADJ	_	Degree=Pos	_	_	_	_
9	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
10	excretion	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	adrenocorticotropic	_	ADJ	_	Degree=Pos	_	_	_	_
14	hormone	_	NOUN	_	Number=Sing	_	_	_	_
15	test	_	NOUN	_	Number=Sing	_	_	_	_
16	before	_	ADP	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	after	_	ADP	_	_	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	FP	_	NOUN	_	Number=Sing	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	high	_	ADJ	_	Degree=Pos	_	_	_	_
3	interindividual	_	ADJ	_	Degree=Pos	_	_	_	_
4	variation	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	GR	_	PROPN	_	Number=Sing	_	_	_	_
7	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	detected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	significant	_	ADJ	_	Degree=Pos	_	_	_	_
7	reduction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	GR	_	NOUN	_	Number=Sing	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	endobronchial	_	ADJ	_	Degree=Pos	_	_	_	_
16	biopsy	_	NOUN	_	Number=Sing	_	_	_	_
17	specimens	_	NOUN	_	Number=Plur	_	_	_	_
18	after	_	ADP	_	_	_	_	_	_
19	FP	_	NOUN	_	Number=Sing	_	_	_	_
20	treatment	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	36.6	_	NUM	_	NumType=Card	_	_	_	_
23	+/-	_	SYM	_	_	_	_	_	_
24	23.1	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	25.0	_	NUM	_	NumType=Card	_	_	_	_
27	+/-	_	SYM	_	_	_	_	_	_
28	10.9	_	NUM	_	NumType=Card	_	_	_	_
29	amol	_	NOUN	_	Number=Sing	_	_	_	_
30	GR	_	NOUN	_	Number=Sing	_	_	_	_
31	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	microg	_	PROPN	_	Number=Sing	_	_	_	_
34	RNA	_	PROPN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	respectively	_	ADV	_	_	_	_	_	_
37	;	_	PUNCT	_	_	_	_	_	_
38	P	_	NOUN	_	Number=Sing	_	_	_	_
39	<.01	_	NUM	_	NumType=Card	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
4	blood	_	NOUN	_	Number=Sing	_	_	_	_
5	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	even	_	ADV	_	_	_	_	_	_
8	more	_	ADV	_	_	_	_	_	_
9	striking	_	ADJ	_	Degree=Pos	_	_	_	_
10	downregulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	GR	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	cognate	_	NOUN	_	Number=Sing	_	_	_	_
17	ligand	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	documented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	30.3	_	NUM	_	NumType=Card	_	_	_	_
22	+/-	_	SYM	_	_	_	_	_	_
23	26.5	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	8.8	_	NUM	_	NumType=Card	_	_	_	_
26	+/-	_	SYM	_	_	_	_	_	_
27	5	_	NUM	_	NumType=Card	_	_	_	_
28	amol	_	NOUN	_	Number=Sing	_	_	_	_
29	GR	_	NOUN	_	Number=Sing	_	_	_	_
30	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	microg	_	PROPN	_	Number=Sing	_	_	_	_
33	RNA	_	PROPN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	respectively	_	ADV	_	_	_	_	_	_
36	;	_	PUNCT	_	_	_	_	_	_
37	P	_	NOUN	_	Number=Sing	_	_	_	_
38	<.001	_	NUM	_	NumType=Card	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	possibly	_	ADV	_	_	_	_	_	_
42	reflecting	_	VERB	_	VerbForm=Ger	_	_	_	_
43	differences	_	NOUN	_	Number=Plur	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
46	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
47	between	_	ADP	_	_	_	_	_	_
48	tissues	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	small	_	ADJ	_	Degree=Pos	_	_	_	_
3	but	_	CCONJ	_	_	_	_	_	_
4	significant	_	ADJ	_	Degree=Pos	_	_	_	_
5	reduction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	24	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	hour	_	NOUN	_	Number=Sing	_	_	_	_
11	urinary	_	ADJ	_	Degree=Pos	_	_	_	_
12	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
13	excretion	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	233	_	NUM	_	NumType=Card	_	_	_	_
18	+/-	_	SYM	_	_	_	_	_	_
19	109	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	157	_	NUM	_	NumType=Card	_	_	_	_
22	+/-	_	SYM	_	_	_	_	_	_
23	66	_	NUM	_	NumType=Card	_	_	_	_
24	nmol	_	NOUN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	L	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	respectively	_	ADV	_	_	_	_	_	_
29	;	_	PUNCT	_	_	_	_	_	_
30	P	_	NOUN	_	Number=Sing	_	_	_	_
31	<.01	_	NUM	_	NumType=Card	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	whereas	_	SCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	feedback	_	NOUN	_	Number=Sing	_	_	_	_
37	regulation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
40	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	means	_	NOUN	_	Number=Plur	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	hypothalamic	_	ADJ	_	Degree=Pos	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	adrenal	_	ADJ	_	Degree=Pos	_	_	_	_
50	axis	_	NOUN	_	Number=Sing	_	_	_	_
51	as	_	SCONJ	_	_	_	_	_	_
52	assessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
53	by	_	ADP	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	adrenocorticotropic	_	ADJ	_	Degree=Pos	_	_	_	_
56	hormone	_	NOUN	_	Number=Sing	_	_	_	_
57	test	_	NOUN	_	Number=Sing	_	_	_	_
58	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
59	normal	_	ADJ	_	Degree=Pos	_	_	_	_
60	after	_	ADP	_	_	_	_	_	_
61	treatment	_	NOUN	_	Number=Sing	_	_	_	_
62	with	_	ADP	_	_	_	_	_	_
63	FP.	_	NOUN	_	Number=Sing	_	_	_	_
64	CONCLUSION	_	NOUN	_	Number=Sing	_	_	_	_
65	:	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	confirm	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	potency	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	inhaled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	corticosteroid	_	NOUN	_	Number=Sing	_	_	_	_
13	FP	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	evidence	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	considerable	_	ADJ	_	Degree=Pos	_	_	_	_
20	tissue	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	interindividual	_	ADJ	_	Degree=Pos	_	_	_	_
24	variation	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	GR	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003454	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Multiple	_	ADJ	_	Degree=Pos	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	ATc	_	PROPN	_	Number=Sing	_	_	_	_
5	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	individual	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	properties	_	NOUN	_	Number=Plur	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	synthesized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	ATc	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	DET	_	PronType=Rel	_	_	_	_
8	controls	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cardiac	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	three	_	NUM	_	NumType=Card	_	_	_	_
22	prominent	_	ADJ	_	Degree=Pos	_	_	_	_
23	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	due	_	ADP	_	_	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
6	splice	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	polyadenylation	_	NOUN	_	Number=Sing	_	_	_	_
9	events	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	predominant	_	ADJ	_	Degree=Pos	_	_	_	_
15	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	long	_	ADJ	_	Degree=Pos	_	_	_	_
19	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	naive	_	ADJ	_	Degree=Pos	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	shorter	_	ADJ	_	Degree=Cmp	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	ATc	_	NOUN	_	Number=Sing	_	_	_	_
30	isoform	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	effector	_	NOUN	_	Number=Sing	_	_	_	_
33	T	_	NOUN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	isoform	_	PROPN	_	Number=Sing	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	ATc	_	PROPN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	A	_	PROPN	_	Number=Sing	_	_	_	_
11	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	relatively	_	ADV	_	_	_	_	_	_
14	short	_	ADJ	_	Degree=Pos	_	_	_	_
15	C	_	NOUN	_	Number=Sing	_	_	_	_
16	terminus	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	longer	_	ADJ	_	Degree=Cmp	_	_	_	_
20	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	B	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	C	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	span	_	VERB	_	Number=Sing	_	_	_	_
27	extra	_	ADJ	_	Degree=Pos	_	_	_	_
28	C	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
31	peptides	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	128	_	NUM	_	NumType=Card	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	246	_	NUM	_	NumType=Card	_	_	_	_
36	aa	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	respectively	_	ADV	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	addition	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	strong	_	ADJ	_	Degree=Pos	_	_	_	_
10	N	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
13	trans	_	NOUN	_	Number=Plur	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	domain	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	TAD	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	A	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	common	_	ADJ	_	Degree=Pos	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	all	_	DET	_	_	_	_	_	_
27	three	_	NUM	_	NumType=Card	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	ATc	_	PROPN	_	Number=Sing	_	_	_	_
31	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	ATc	_	PROPN	_	Number=Sing	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	C	_	PROPN	_	Number=Sing	_	_	_	_
38	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
41	trans	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	activation	_	NOUN	_	Number=Sing	_	_	_	_
44	domain	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	TAD	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	B	_	PROPN	_	_	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
52	C	_	NOUN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	terminal	_	NOUN	_	Number=Sing	_	_	_	_
55	peptide	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Various	_	ADJ	_	Degree=Pos	_	_	_	_
2	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	TAD	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	A	_	PROPN	_	Number=Sing	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	TAD	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	B	_	PROPN	_	Degree=Pos	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	unlike	_	ADP	_	_	_	_	_	_
26	TAD	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	A	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	TAD	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	unphosphorylated	_	ADJ	_	Degree=Pos	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	protein	_	NOUN	_	Number=Sing	_	_	_	_
37	from	_	ADP	_	_	_	_	_	_
38	12	_	NUM	_	NumType=Card	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	O-tetradecanoyl	_	NOUN	_	Number=Sing	_	_	_	_
41	12	_	NUM	_	NumType=Card	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
44	13	_	NUM	_	NumType=Card	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	acetate	_	ADJ	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	T	_	NOUN	_	Number=Sing	_	_	_	_
50	cells	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	shorter	_	ADJ	_	Degree=Pos	_	_	_	_
3	C-	_	PUNCT	_	Number=Sing	_	_	_	_
4	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
5	peptide	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	isoform	_	PROPN	_	Number=Sing	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	ATc	_	PROPN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	suppressive	_	ADJ	_	Degree=Pos	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	effect	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	properties	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	ATc	_	PROPN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	-C	_	PROPN	_	Number=Sing	_	_	_	_
11	might	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	importance	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	naive	_	ADJ	_	Degree=Pos	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	ATc	_	PROPN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	B	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	C	_	NOUN	_	Number=Sing	_	_	_	_
32	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	predominantly	_	ADV	_	_	_	_	_	_
34	synthesized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003456	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Latent	_	ADJ	_	Degree=Pos	_	_	_	_
2	membrane	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	induces	_	NOUN	_	Number=Plur	_	_	_	_
7	cyclin	_	NOUN	_	Number=Sing	_	_	_	_

1	D2	_	NUM	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	pRb	_	NOUN	_	Number=Sing	_	_	_	_
5	hyperphosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	loss	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	TGF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	beta	_	NOUN	_	Number=Sing	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	VERB	_	Degree=Pos	_	_	_	_
16	growth	_	NOUN	_	Number=Sing	_	_	_	_
17	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	EBV	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	positive	_	ADJ	_	Degree=Pos	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	normal	_	ADJ	_	Degree=Pos	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	cycle	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	several	_	ADJ	_	Degree=Pos	_	_	_	_
9	molecules	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	such	_	ADJ	_	Degree=Pos	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	tumor	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	pRb	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	G1	_	PROPN	_	Number=Sing	_	_	_	_
22	cyclins	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	kinases	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
32	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	regulators	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	targeted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	negative	_	ADJ	_	Degree=Pos	_	_	_	_
7	growth	_	NOUN	_	Number=Sing	_	_	_	_
8	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	signals	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	such	_	ADJ	_	Degree=Pos	_	_	_	_
12	as	_	SCONJ	_	_	_	_	_	_
13	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
14	provided	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	TGF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	beta	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	presence	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	either	_	CCONJ	_	_	_	_	_	_
10	wild	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	type	_	NOUN	_	Number=Sing	_	_	_	_
13	EBV	_	PROPN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	transforming	_	NOUN	_	VerbForm=Ger	_	_	_	_
17	latent	_	ADJ	_	Degree=Pos	_	_	_	_
18	membrane	_	NOUN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	LMP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	results	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	loss	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	TGF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	beta	_	NOUN	_	Number=Sing	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	mediated	_	VERB	_	Degree=Pos	_	_	_	_
38	growth	_	NOUN	_	Number=Sing	_	_	_	_
39	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	human	_	ADJ	_	Degree=Pos	_	_	_	_
42	B	_	NOUN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Chemical	_	PROPN	_	Degree=Pos	_	_	_	_
2	cross	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	125I	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	labeled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	TGF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	essentially	_	ADV	_	_	_	_	_	_
16	normal	_	ADJ	_	Degree=Pos	_	_	_	_
17	TGF	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	profile	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	EBV	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	positive	_	ADJ	_	Degree=Pos	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	EBV	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	negative	_	ADJ	_	Degree=Pos	_	_	_	_
30	Burkitt	_	NOUN	_	Number=Sing	_	_	_	_
31	's	_	PART	_	_	_	_	_	_
32	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	lines	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
38	receptors	_	NOUN	_	Number=Plur	_	_	_	_
39	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	to	_	PART	_	_	_	_	_	_
42	be	_	AUX	_	VerbForm=Inf	_	_	_	_
43	functional	_	ADJ	_	Degree=Pos	_	_	_	_
44	in	_	SCONJ	_	_	_	_	_	_
45	transducing	_	VERB	_	VerbForm=Ger	_	_	_	_
46	signals	_	NOUN	_	Number=Plur	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	as	_	SCONJ	_	_	_	_	_	_
49	evidenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	by	_	ADP	_	_	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	TGF	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	beta	_	NOUN	_	Number=Sing	_	_	_	_
55	1	_	NUM	_	NumType=Card	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
58	modulation	_	NOUN	_	Number=Sing	_	_	_	_
59	of	_	ADP	_	_	_	_	_	_
60	junB	_	NOUN	_	Degree=Pos	_	_	_	_
61	gene	_	NOUN	_	Number=Sing	_	_	_	_
62	expression	_	NOUN	_	Number=Sing	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	TGF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
10	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	pRb	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	EBV	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	LMP	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	positive	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	opposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	EBV	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	negative	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	dichotomy	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	TGF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	beta	_	NOUN	_	Number=Sing	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
42	pathway	_	NOUN	_	Number=Sing	_	_	_	_
43	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
44	to	_	ADP	_	_	_	_	_	_
45	separable	_	ADJ	_	Degree=Pos	_	_	_	_
46	gene	_	NOUN	_	Number=Sing	_	_	_	_
47	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	growth	_	NOUN	_	Number=Sing	_	_	_	_
50	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
51	responses	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	LMP	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
14	D2	_	NOUN	_	Number=Sing	_	_	_	_
15	;	_	PUNCT	_	_	_	_	_	_
16	normal	_	ADJ	_	Degree=Pos	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	EBV	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	negative	_	ADJ	_	Degree=Pos	_	_	_	_
23	Burkitt	_	NOUN	_	Number=Sing	_	_	_	_
24	's	_	PART	_	_	_	_	_	_
25	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	express	_	VERB	_	VerbForm=Inf	_	_	_	_
30	D	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	type	_	NOUN	_	Number=Sing	_	_	_	_
33	cyclins	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	point	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	potential	_	ADJ	_	Degree=Pos	_	_	_	_
10	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
11	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
12	EBV	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	transformation	_	NOUN	_	Number=Sing	_	_	_	_
18	whereby	_	ADV	_	_	_	_	_	_
19	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
20	induction	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	key	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	cycle	_	NOUN	_	Number=Sing	_	_	_	_
25	regulators	_	NOUN	_	Number=Plur	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	LMP	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	can	_	AUX	_	VerbForm=Fin	_	_	_	_
31	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	pRb	_	NOUN	_	VerbForm=Inf	_	_	_	_
34	hyperphosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	uncontrolled	_	ADJ	_	Degree=Pos	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003457	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	12	_	NUM	_	NumType=Card	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	NK	_	PROPN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	line	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	important	_	ADJ	_	Degree=Pos	_	_	_	_
12	immunoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	predominantly	_	ADV	_	_	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	large	_	ADJ	_	Degree=Pos	_	_	_	_
21	granular	_	ADJ	_	Degree=Pos	_	_	_	_
22	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	LGL	_	X	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	response	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	different	_	ADJ	_	Degree=Pos	_	_	_	_
30	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
31	signals	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	particular	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	interleukins	_	NOUN	_	Number=Plur	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	ILs	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	12	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
20	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	potent	_	ADJ	_	Degree=Pos	_	_	_	_
24	inducers	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	IFN	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	gamma	_	NOUN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	both	_	CCONJ	_	_	_	_	_	_
33	T	_	PROPN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	LGL	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	there	_	PRON	_	_	_	_	_	_
8	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	some	_	DET	_	_	_	_	_	_
10	T	_	NUM	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	lines	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	produce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	IFN	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	gamma	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	12	_	NUM	_	NumType=Card	_	_	_	_
28	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	there	_	PRON	_	_	_	_	_	_
31	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	as	_	ADV	_	_	_	_	_	_
33	yet	_	ADV	_	_	_	_	_	_
34	been	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	no	_	DET	_	_	_	_	_	_
36	report	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	natural	_	ADJ	_	Degree=Pos	_	_	_	_
40	killer	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	NK	_	PROPN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	cell	_	NOUN	_	Number=Sing	_	_	_	_
45	line	_	NOUN	_	Number=Sing	_	_	_	_
46	that	_	PRON	_	PronType=Rel	_	_	_	_
47	responds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
50	similar	_	ADJ	_	Degree=Pos	_	_	_	_
51	manner	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	present	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	evidence	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	NK3.3	_	PROPN	_	Number=Sing	_	_	_	_
12	derived	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	NK	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	responds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	12	_	NUM	_	NumType=Card	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	as	_	SCONJ	_	_	_	_	_	_
30	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	increases	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	IFN	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	gamma	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
41	colony	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
44	factor	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	GM	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	CSF	_	PROPN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
51	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	protein	_	NOUN	_	Number=Sing	_	_	_	_
54	expression	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	when	_	ADV	_	PronType=Int	_	_	_	_
5	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	together	_	ADV	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	12	_	NUM	_	NumType=Card	_	_	_	_
14	synergized	_	VERB	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	IFN	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	gamma	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	GM	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	CSF	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	synergy	_	NOUN	_	Number=Sing	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	attributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	stability	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	IFN	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	gamma	_	NOUN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	GM	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	CSF	_	PROPN	_	Number=Sing	_	_	_	_
46	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	signaling	_	NOUN	_	Number=Sing	_	_	_	_
5	pathways	_	NOUN	_	Number=Plur	_	_	_	_
6	involved	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	five	_	NUM	_	NumType=Card	_	_	_	_
13	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
16	A	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	CsA	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
22	growth	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	beta	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	genistein	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	staurosporine	_	NOUN	_	Number=Sing	_	_	_	_
33	A	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	in	_	SCONJ	_	_	_	_	_	_
38	analyzing	_	VERB	_	VerbForm=Ger	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	effects	_	NOUN	_	Number=Plur	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	2	_	NUM	_	NumType=Card	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	IL	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	12	_	NUM	_	NumType=Card	_	_	_	_
49	on	_	ADP	_	_	_	_	_	_
50	NK3.3	_	NUM	_	Number=Sing	_	_	_	_
51	cells	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	C	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	ADV	_	_	_	_	_	_
13	new	_	ADJ	_	Degree=Pos	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	induction	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	IFN	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	gamma	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	GM	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	CSF	_	PROPN	_	Number=Sing	_	_	_	_
32	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
33	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	12	_	NUM	_	NumType=Card	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IFN	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	only	_	ADV	_	_	_	_	_	_
17	partially	_	ADV	_	_	_	_	_	_
18	depend	_	VERB	_	VerbForm=Inf	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	C.	_	PROPN	_	Number=Sing	_	_	_	_
25	Furthermore	_	ADV	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	both	_	DET	_	_	_	_	_	_
28	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
29	growth	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	beta	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	genistein	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
38	kinase	_	NOUN	_	Number=Sing	_	_	_	_
39	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	could	_	AUX	_	VerbForm=Fin	_	_	_	_
42	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
43	IL	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	2	_	NUM	_	NumType=Card	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	IL	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	12	_	NUM	_	NumType=Card	_	_	_	_
50	signaling	_	NOUN	_	Number=Sing	_	_	_	_
51	but	_	CCONJ	_	_	_	_	_	_
52	CsA	_	PROPN	_	Number=Sing	_	_	_	_
53	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
54	generally	_	ADV	_	_	_	_	_	_
55	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	suppression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	agents	_	NOUN	_	Number=Plur	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	independent	_	ADJ	_	Degree=Pos	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	but	_	CCONJ	_	_	_	_	_	_
8	not	_	ADV	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	12	_	NUM	_	NumType=Card	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	AP1	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	regulation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	levels	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
30	two	_	NUM	_	NumType=Card	_	_	_	_
31	DNA	_	PROPN	_	Number=Sing	_	_	_	_
32	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
33	protein	_	NOUN	_	Number=Sing	_	_	_	_
34	complexes	_	NOUN	_	Number=Plur	_	_	_	_
35	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	IFN	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	gamma	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	GM	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	CSF	_	PROPN	_	Number=Sing	_	_	_	_
45	gene	_	NOUN	_	Number=Sing	_	_	_	_
46	expression	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	12	_	NUM	_	NumType=Card	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	have	_	VERB	_	VerbForm=Inf	_	_	_	_
14	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
15	signaling	_	VERB	_	Number=Sing	_	_	_	_
16	pathways	_	NOUN	_	Number=Plur	_	_	_	_
17	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	induction	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	IFN	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	gamma	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	GM	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	CSF	_	PROPN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	that	_	SCONJ	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	NK3.3	_	NOUN	_	Number=Sing	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	line	_	NOUN	_	Number=Sing	_	_	_	_
38	may	_	AUX	_	VerbForm=Fin	_	_	_	_
39	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
40	as	_	ADP	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	novel	_	NOUN	_	Number=Sing	_	_	_	_
43	model	_	NOUN	_	Number=Sing	_	_	_	_
44	for	_	SCONJ	_	_	_	_	_	_
45	dissecting	_	VERB	_	VerbForm=Ger	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
50	events	_	NOUN	_	Number=Plur	_	_	_	_
51	involved	_	ADJ	_	Degree=Pos	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
54	pathways	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003458	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Jeg	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	choriocarcinoma	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	immunosuppression	_	NOUN	_	Number=Sing	_	_	_	_
9	:	_	PUNCT	_	_	_	_	_	_
10	downregulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	chain	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	Jak	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	Stat	_	PROPN	_	Number=Sing	_	_	_	_
29	signaling	_	VERB	_	Number=Sing	_	_	_	_
30	pathway	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	PROBLEM	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	immunosuppression	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	capacities	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Jeg	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	3	_	NUM	_	NumType=Card	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	choriocarcinoma	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	line	_	NOUN	_	Number=Sing	_	_	_	_
19	supernatants	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	HCSs	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	yet	_	ADV	_	_	_	_	_	_
26	completely	_	ADV	_	_	_	_	_	_
27	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	influence	_	NOUN	_	Number=Sing	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	interferon	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	IFN	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	gamma	_	NOUN	_	Number=Sing	_	_	_	_
21	production	_	NOUN	_	Number=Sing	_	_	_	_
22	;	_	PUNCT	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2R	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	alpha	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	beta	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	gamma	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	chain	_	NOUN	_	Number=Sing	_	_	_	_
42	;	_	PUNCT	_	_	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	signaling	_	NOUN	_	Number=Sing	_	_	_	_
46	pathway	_	NOUN	_	Number=Sing	_	_	_	_
47	molecules	_	NOUN	_	Number=Plur	_	_	_	_
48	Janus	_	PROPN	_	Number=Sing	_	_	_	_
49	kinase	_	NOUN	_	Number=Sing	_	_	_	_
50	(	_	PUNCT	_	_	_	_	_	_
51	Jak	_	PROPN	_	Number=Sing	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	1	_	NUM	_	NumType=Card	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	Jak3	_	NOUN	_	Number=Sing	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	signal	_	NOUN	_	Number=Sing	_	_	_	_
58	transducers	_	NOUN	_	Number=Plur	_	_	_	_
59	and	_	CCONJ	_	_	_	_	_	_
60	activators	_	NOUN	_	Number=Plur	_	_	_	_
61	of	_	ADP	_	_	_	_	_	_
62	transcription	_	NOUN	_	Number=Sing	_	_	_	_
63	(	_	PUNCT	_	_	_	_	_	_
64	Stat	_	PROPN	_	Number=Sing	_	_	_	_
65	)	_	PUNCT	_	_	_	_	_	_
66	1	_	NUM	_	NumType=Card	_	_	_	_
67	,	_	PUNCT	_	_	_	_	_	_
68	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
69	,	_	PUNCT	_	_	_	_	_	_
70	and	_	CCONJ	_	_	_	_	_	_
71	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
72	should	_	AUX	_	VerbForm=Fin	_	_	_	_
73	be	_	AUX	_	VerbForm=Inf	_	_	_	_
74	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
75	.	_	PUNCT	_	_	_	_	_	_

1	METHOD	_	NOUN	_	Number=Sing	_	_	_	_
2	OF	_	ADP	_	_	_	_	_	_
3	STUDY	_	PROPN	_	Number=Sing	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	assessment	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	production	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	whole	_	ADJ	_	Degree=Pos	_	_	_	_
8	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
9	venous	_	ADJ	_	Degree=Pos	_	_	_	_
10	blood	_	NOUN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
13	donors	_	NOUN	_	Number=Plur	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	myristate	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	acetate	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	ionomycine	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Secretion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	ILs	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	monensine	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	ILs	_	PROPN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	flow	_	NOUN	_	Number=Sing	_	_	_	_
7	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2R	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
7	pathway	_	NOUN	_	Number=Sing	_	_	_	_
8	molecule	_	NOUN	_	Number=Sing	_	_	_	_
9	analysis	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
12	blood	_	NOUN	_	Number=Sing	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	PHA	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2R	_	NUM	_	Number=Sing	_	_	_	_
4	chains	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	flow	_	NOUN	_	Number=Sing	_	_	_	_
9	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Jaks	_	PROPN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	Stats	_	PROPN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	sodium	_	NOUN	_	Number=Sing	_	_	_	_
17	dodecyl	_	NOUN	_	Number=Sing	_	_	_	_
18	sulfate	_	NOUN	_	Number=Sing	_	_	_	_
19	polyacrylamide	_	NOUN	_	Number=Sing	_	_	_	_
20	gel	_	NOUN	_	Number=Sing	_	_	_	_
21	electrophoresis	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	SDS	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	PAGE	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	Western	_	ADJ	_	Degree=Pos	_	_	_	_
29	blot	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Phorbol	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	myristate	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	acetate	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	ionomycine	_	NOUN	_	Number=Sing	_	_	_	_
10	strongly	_	ADV	_	_	_	_	_	_
11	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	percent	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	age	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	;	_	PUNCT	_	_	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	additional	_	ADJ	_	Degree=Pos	_	_	_	_
25	50	_	NUM	_	NumType=Card	_	_	_	_
26	%	_	SYM	_	Number=Sing	_	_	_	_
27	HCSs	_	NOUN	_	Number=Sing	_	_	_	_
28	significantly	_	ADV	_	_	_	_	_	_
29	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	percentage	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	below	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	level	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	IFN	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	production	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	strongly	_	ADV	_	_	_	_	_	_
7	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	HCSs	_	PROPN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	some	_	DET	_	_	_	_	_	_
12	cases	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	others	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	PHA	_	PROPN	_	Number=Sing	_	_	_	_
2	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2R	_	NUM	_	Number=Sing	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	beta	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	chain	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	signaling	_	NOUN	_	Number=Sing	_	_	_	_
20	pathway	_	NOUN	_	Number=Sing	_	_	_	_
21	molecules	_	NOUN	_	Number=Plur	_	_	_	_
22	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	50	_	NUM	_	NumType=Card	_	_	_	_
2	%	_	SYM	_	Number=Sing	_	_	_	_
3	HCS	_	PROPN	_	Number=Sing	_	_	_	_
4	downregulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	chain	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	slightly	_	ADV	_	_	_	_	_	_
11	upregulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	chain	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	approximately	_	ADV	_	_	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	below	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	HCS	_	PROPN	_	Number=Sing	_	_	_	_
4	forcefully	_	ADV	_	_	_	_	_	_
5	blocks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	production	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	;	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2R	_	PROPN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	chain	_	NOUN	_	Number=Sing	_	_	_	_
20	;	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	phenomena	_	NOUN	_	Number=Sing	_	_	_	_
4	might	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	caused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	downregulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2R	_	ADJ	_	Number=Sing	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	might	_	AUX	_	VerbForm=Fin	_	_	_	_
19	play	_	VERB	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	key	_	ADJ	_	Degree=Pos	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	expansion	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	choriocarcinoma	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	possibly	_	ADV	_	_	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	survival	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	fetal	_	NOUN	_	Number=Sing	_	_	_	_
37	allograft	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003459	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Signal	_	ADJ	_	Number=Sing	_	_	_	_
2	transduction	_	NOUN	_	Number=Sing	_	_	_	_
3	through	_	ADP	_	_	_	_	_	_
4	interferon	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	gamma	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
6	interferon	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	IFN	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	gammaR	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	But	_	CCONJ	_	_	_	_	_	_
2	signal	_	NOUN	_	Number=Sing	_	_	_	_
3	transduction	_	NOUN	_	Number=Sing	_	_	_	_
4	through	_	ADP	_	_	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	gammaR	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
10	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	elucidated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	involvement	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	Jak	_	PROPN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	Stat	_	PROPN	_	Number=Sing	_	_	_	_
14	pathway	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	signaling	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
20	after	_	ADP	_	_	_	_	_	_
21	IFN	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	gammaR	_	NOUN	_	Number=Sing	_	_	_	_
24	conjugation	_	NOUN	_	Number=Sing	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	ligand	_	NOUN	_	Number=Sing	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Purified	_	VERB	_	Degree=Pos	_	_	_	_
4	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
5	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	IFN	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	37	_	NUM	_	NumType=Card	_	_	_	_
14	degrees	_	NOUN	_	Number=Plur	_	_	_	_
15	C	_	PROPN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	1-60	_	NUM	_	NumType=Card	_	_	_	_
18	min	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Tyrosine	_	PROPN	_	Number=Sing	_	_	_	_
2	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IFN	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	gammaR	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	Jak2	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	Stat1alpha	_	PROPN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	immunoblotting	_	ADJ	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	examined	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	show	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	formation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Stat1alpha	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	DNA	_	PROPN	_	Number=Sing	_	_	_	_
16	complexes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
12	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	series	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	events	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
22	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
23	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	not	_	ADV	_	_	_	_	_	_
26	only	_	ADV	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	IFN	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	gammaRalpha	_	NOUN	_	Number=Sing	_	_	_	_
31	chain	_	NOUN	_	Number=Sing	_	_	_	_
32	but	_	CCONJ	_	_	_	_	_	_
33	also	_	ADV	_	_	_	_	_	_
34	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	Jak2	_	PROPN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	Stat1alpha	_	PROPN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	IFN	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	gamma	_	NOUN	_	Number=Sing	_	_	_	_
7	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	DNA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	Stat1alpha	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSION	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
10	through	_	ADP	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	utilizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	Jak	_	PROPN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	Stat	_	PROPN	_	Number=Sing	_	_	_	_
20	pathway	_	NOUN	_	Number=Sing	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	mode	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	signaling	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003462	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Ras	_	PROPN	_	Number=Sing	_	_	_	_
2	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
3	transformation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	lymphoblasts	_	NOUN	_	Number=Plur	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	block	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	p21ras	_	NOUN	_	_	_	_	_	_
3	small	_	ADJ	_	Degree=Pos	_	_	_	_
4	GTP	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
6	proteins	_	NOUN	_	Number=Plur	_	_	_	_
7	participate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	signal	_	NOUN	_	Number=Sing	_	_	_	_
10	transduction	_	NOUN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	surface	_	NOUN	_	Number=Sing	_	_	_	_
14	receptors	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
17	neoplastic	_	ADJ	_	Degree=Pos	_	_	_	_
18	transformation	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	development	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	many	_	ADJ	_	Degree=Pos	_	_	_	_
23	different	_	ADJ	_	Degree=Pos	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	types	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	relationship	_	NOUN	_	Number=Sing	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	ras	_	NOUN	_	Number=Sing	_	_	_	_
12	transformation	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	T24	_	PROPN	_	Number=Sing	_	_	_	_
10	Ha	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	ras	_	NOUN	_	Number=Sing	_	_	_	_
13	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	EBV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	immortalized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	B	_	PROPN	_	Number=Sing	_	_	_	_
19	lymphoblasts	_	NOUN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	induction	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	subunit	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
36	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
37	gene	_	NOUN	_	Number=Sing	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
42	properties	_	NOUN	_	Number=Plur	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	survival	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	serum	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	free	_	ADJ	_	Degree=Pos	_	_	_	_
50	medium	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	ADP	_	_	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	subunit	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	hallmark	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	lymphocyte	_	ADJ	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
22	naturally	_	ADV	_	_	_	_	_	_
23	triggers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ras	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	displayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	fully	_	ADV	_	_	_	_	_	_
9	functional	_	ADJ	_	Degree=Pos	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2r	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	as	_	SCONJ	_	_	_	_	_	_
15	assessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	following	_	VERB	_	VerbForm=Ger	_	_	_	_
20	treatment	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	;	_	PUNCT	_	_	_	_	_	_
26	nevertheless	_	ADV	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
29	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	not	_	PART	_	_	_	_	_	_
31	growth	_	NOUN	_	Number=Sing	_	_	_	_
32	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
35	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	ras	_	NOUN	_	Number=Sing	_	_	_	_
11	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
12	blocks	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	plasma	_	VERB	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	possibly	_	ADV	_	_	_	_	_	_
20	by	_	SCONJ	_	_	_	_	_	_
21	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	factors	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Somewhat	_	ADV	_	_	_	_	_	_
2	unexpectedly	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
6	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	cause	_	VERB	_	VerbForm=Inf	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	PEA1	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	AP1	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	PEA3	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	Oct	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kB	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003463	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	New	_	PROPN	_	Number=Sing	_	_	_	_
11	World	_	PROPN	_	Number=Sing	_	_	_	_
12	primate	_	ADJ	_	Degree=Pos	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	extracts	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	if	_	SCONJ	_	_	_	_	_	_
4	New	_	PROPN	_	Number=Sing	_	_	_	_
5	World	_	PROPN	_	Number=Sing	_	_	_	_
6	primates	_	NOUN	_	Number=Plur	_	_	_	_
7	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	influences	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	GR	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
18	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
21	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	[	_	PUNCT	_	_	_	_	_	_
23	3H	_	X	_	Number=Sing	_	_	_	_
24	]	_	PUNCT	_	_	_	_	_	_
25	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
29	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	B95	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	SYM	_	_	_	_	_	_
33	8	_	NUM	_	NumType=Card	_	_	_	_
34	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	from	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	cotton	_	NOUN	_	Number=Sing	_	_	_	_
41	top	_	ADJ	_	Degree=Pos	_	_	_	_
42	tamarin	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	Saguinus	_	PROPN	_	Number=Sing	_	_	_	_
45	oedipus	_	NOUN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	combination	_	NOUN	_	Number=Sing	_	_	_	_
50	with	_	ADP	_	_	_	_	_	_
51	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
52	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
53	from	_	ADP	_	_	_	_	_	_
54	human	_	ADJ	_	Degree=Pos	_	_	_	_
55	or	_	CCONJ	_	_	_	_	_	_
56	rat	_	NOUN	_	Number=Sing	_	_	_	_
57	tissues	_	NOUN	_	Number=Plur	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	B95	_	NUM	_	Number=Sing	_	_	_	_
2	-	_	SYM	_	_	_	_	_	_
3	8	_	NUM	_	NumType=Card	_	_	_	_
4	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
5	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	[	_	PUNCT	_	_	_	_	_	_
10	3H	_	NUM	_	Number=Sing	_	_	_	_
11	]	_	PUNCT	_	_	_	_	_	_
12	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	P	_	NOUN	_	Number=Sing	_	_	_	_
15	<	_	PUNCT	_	_	_	_	_	_
16	0.01	_	NUM	_	NumType=Card	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	when	_	ADV	_	PronType=Int	_	_	_	_
19	mixed	_	VERB	_	Degree=Pos	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
22	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	either	_	CCONJ	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	line	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	HL	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	rat	_	NOUN	_	Number=Sing	_	_	_	_
35	thymus	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	heat	_	NOUN	_	Number=Sing	_	_	_	_
6	labile	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	trypsin	_	NOUN	_	_	_	_	_	_
9	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Peak	_	NOUN	_	Number=Sing	_	_	_	_
2	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	150	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	SYM	_	_	_	_	_	_
10	200	_	NUM	_	NumType=Card	_	_	_	_
11	kd	_	NOUN	_	Number=Sing	_	_	_	_
12	fractions	_	NOUN	_	Number=Plur	_	_	_	_
13	after	_	ADP	_	_	_	_	_	_
14	Sephacryl	_	PROPN	_	Number=Sing	_	_	_	_
15	G	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	200	_	NUM	_	NumType=Card	_	_	_	_
18	ultrafiltration	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Scatchard	_	ADJ	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	[	_	PUNCT	_	_	_	_	_	_
5	3H	_	NOUN	_	Number=Sing	_	_	_	_
6	]	_	PUNCT	_	_	_	_	_	_
7	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	using	_	VERB	_	VerbForm=Ger	_	_	_	_
10	mixed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
12	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	diminished	_	ADJ	_	Degree=Pos	_	_	_	_
15	GR	_	NOUN	_	Number=Sing	_	_	_	_
16	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	affinity	_	NOUN	_	Number=Sing	_	_	_	_
19	when	_	ADV	_	PronType=Int	_	_	_	_
20	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	HL	_	PROPN	_	Number=Sing	_	_	_	_
23	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Kinetic	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	using	_	VERB	_	VerbForm=Ger	_	_	_	_
4	mixed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
6	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	B95	_	NUM	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	8	_	NUM	_	NumType=Card	_	_	_	_
11	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
12	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
17	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
18	rate	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	[	_	PUNCT	_	_	_	_	_	_
21	3H	_	NOUN	_	Number=Sing	_	_	_	_
22	]	_	PUNCT	_	_	_	_	_	_
23	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	B95	_	NUM	_	Number=Sing	_	_	_	_
6	-	_	SYM	_	_	_	_	_	_
7	8	_	NUM	_	NumType=Card	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	competitive	_	ADJ	_	Degree=Pos	_	_	_	_
12	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	cognate	_	NOUN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003465	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Age	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	related	_	ADJ	_	Degree=Pos	_	_	_	_
4	decreases	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	AP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	AT	_	NOUN	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	AT	_	NOUN	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	important	_	ADJ	_	Degree=Pos	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	normal	_	ADJ	_	Degree=Pos	_	_	_	_
24	induction	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
33	if	_	SCONJ	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	age	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	related	_	ADJ	_	Degree=Pos	_	_	_	_
38	decline	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	2	_	NUM	_	NumType=Card	_	_	_	_
43	production	_	NOUN	_	Number=Sing	_	_	_	_
44	by	_	ADP	_	_	_	_	_	_
45	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	human	_	ADJ	_	Degree=Pos	_	_	_	_
47	T	_	NOUN	_	Number=Sing	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	may	_	AUX	_	VerbForm=Fin	_	_	_	_
50	be	_	AUX	_	VerbForm=Inf	_	_	_	_
51	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	with	_	ADP	_	_	_	_	_	_
53	aberrancies	_	NOUN	_	Number=Plur	_	_	_	_
54	in	_	ADP	_	_	_	_	_	_
55	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
56	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
57	proteins	_	NOUN	_	Number=Plur	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	current	_	ADJ	_	Degree=Pos	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	mean	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	78	_	NUM	_	NumType=Card	_	_	_	_
18	years	_	NOUN	_	Number=Plur	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	young	_	ADJ	_	Degree=Pos	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	mean	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	37	_	NUM	_	NumType=Card	_	_	_	_
25	years	_	NOUN	_	Number=Plur	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	humans	_	NOUN	_	Number=Plur	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	cultures	_	NOUN	_	Number=Plur	_	_	_	_
32	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	PHA	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	PHA	_	PROPN	_	Number=Sing	_	_	_	_
37	plus	_	CCONJ	_	_	_	_	_	_
38	PMA	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	crosslinked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	anti-CD3	_	NUM	_	Number=Sing	_	_	_	_
42	mAB	_	NOUN	_	Number=Sing	_	_	_	_
43	OKT3	_	NOUN	_	Number=Sing	_	_	_	_
44	plus	_	CCONJ	_	_	_	_	_	_
45	PMA	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	or	_	CCONJ	_	_	_	_	_	_
48	PMA	_	PROPN	_	Number=Sing	_	_	_	_
49	plus	_	CCONJ	_	_	_	_	_	_
50	ionomycin	_	PROPN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Substantial	_	ADJ	_	Degree=Pos	_	_	_	_
2	decreases	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	production	_	NOUN	_	Number=Sing	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	cultures	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	7	_	NUM	_	NumType=Card	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	12	_	NUM	_	NumType=Card	_	_	_	_
17	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
18	individuals	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	response	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	different	_	ADJ	_	Degree=Pos	_	_	_	_
24	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	whereas	_	SCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	levels	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	T	_	PROPN	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	from	_	ADP	_	_	_	_	_	_
39	other	_	ADJ	_	Degree=Pos	_	_	_	_
40	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
41	individuals	_	NOUN	_	Number=Plur	_	_	_	_
42	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	equivalent	_	ADJ	_	Degree=Pos	_	_	_	_
44	to	_	ADP	_	_	_	_	_	_
45	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
46	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	for	_	ADP	_	_	_	_	_	_
48	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	T	_	PROPN	_	Number=Sing	_	_	_	_
50	cells	_	NOUN	_	Number=Plur	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	young	_	ADJ	_	Degree=Pos	_	_	_	_
53	subjects	_	NOUN	_	Number=Plur	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Analyses	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	extracts	_	NOUN	_	Number=Plur	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
7	DNA	_	PROPN	_	Number=Sing	_	_	_	_
8	mobility	_	NOUN	_	Number=Sing	_	_	_	_
9	shift	_	NOUN	_	Number=Sing	_	_	_	_
10	assays	_	NOUN	_	Number=Plur	_	_	_	_
11	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
24	individuals	_	NOUN	_	Number=Plur	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	closely	_	ADV	_	_	_	_	_	_
27	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	impairments	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	both	_	CCONJ	_	_	_	_	_	_
35	AP	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	AT	_	NOUN	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
8	subjects	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	normal	_	ADJ	_	Degree=Pos	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	exhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	AP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	AT	_	NOUN	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	competition	_	NOUN	_	Number=Sing	_	_	_	_
8	experiments	_	NOUN	_	Number=Plur	_	_	_	_
9	analyzing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	normal	_	ADJ	_	Degree=Pos	_	_	_	_
12	components	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	AT	_	ADP	_	_	_	_	_	_
17	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	age	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	related	_	ADJ	_	Degree=Pos	_	_	_	_
23	reductions	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	stimulus	_	ADJ	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	NF	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	AT	_	ADP	_	_	_	_	_	_
31	complexes	_	NOUN	_	Number=Plur	_	_	_	_
32	corresponded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	slow	_	ADJ	_	Degree=Pos	_	_	_	_
36	migrating	_	NOUN	_	Number=Sing	_	_	_	_
37	complexes	_	NOUN	_	Number=Plur	_	_	_	_
38	that	_	PRON	_	PronType=Rel	_	_	_	_
39	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
43	/	_	PUNCT	_	_	_	_	_	_
44	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
45	AP	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	resting	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	certain	_	ADJ	_	Degree=Pos	_	_	_	_
17	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
18	individuals	_	NOUN	_	Number=Plur	_	_	_	_
19	;	_	PUNCT	_	_	_	_	_	_
20	however	_	ADV	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	alterations	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	kappa	_	PROPN	_	Number=Sing	_	_	_	_
26	B	_	PROPN	_	Number=Sing	_	_	_	_
27	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	correlate	_	VERB	_	VerbForm=Inf	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	changes	_	NOUN	_	Number=Plur	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	age	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	related	_	ADJ	_	Degree=Pos	_	_	_	_
10	impairments	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	AT	_	PROPN	_	_	_	_	_	_
22	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	closely	_	ADV	_	_	_	_	_	_
24	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	further	_	ADV	_	Degree=Cmp	_	_	_	_
34	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	that	_	SCONJ	_	_	_	_	_	_
36	aberrancies	_	NOUN	_	Number=Plur	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	signaling	_	NOUN	_	Number=Sing	_	_	_	_
40	pathways	_	NOUN	_	Number=Plur	_	_	_	_
41	important	_	ADJ	_	Degree=Pos	_	_	_	_
42	for	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	induction	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	transcriptionally	_	ADV	_	_	_	_	_	_
47	active	_	ADJ	_	Degree=Pos	_	_	_	_
48	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
49	/	_	PUNCT	_	_	_	_	_	_
50	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
51	AP	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	1	_	NUM	_	NumType=Card	_	_	_	_
54	may	_	AUX	_	VerbForm=Fin	_	_	_	_
55	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
56	to	_	ADP	_	_	_	_	_	_
57	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
58	impaired	_	VERB	_	Degree=Pos	_	_	_	_
59	activation	_	NOUN	_	Number=Sing	_	_	_	_
60	of	_	ADP	_	_	_	_	_	_
61	NF	_	PROPN	_	Number=Sing	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	AT	_	NOUN	_	_	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003469	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Dimerization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	KB2	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	RelA	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	p65	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	MAD	_	ADJ	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Inducible	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
9	subunits	_	NOUN	_	Number=Plur	_	_	_	_
10	;	_	PUNCT	_	_	_	_	_	_
11	five	_	NUM	_	NumType=Card	_	_	_	_
12	independent	_	ADJ	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	NFKB1	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	p105	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	NFKB2	_	PROPN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	p100	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	RelA	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	p65	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	relB	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
35	encode	_	VERB	_	Number=Sing	_	_	_	_
36	related	_	ADJ	_	Degree=Pos	_	_	_	_
37	proteins	_	NOUN	_	Number=Plur	_	_	_	_
38	that	_	PRON	_	PronType=Rel	_	_	_	_
39	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	kappa	_	PROPN	_	Number=Sing	_	_	_	_
42	B	_	NOUN	_	Number=Sing	_	_	_	_
43	DNA	_	NOUN	_	Number=Sing	_	_	_	_
44	elements	_	NOUN	_	Number=Plur	_	_	_	_
45	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
46	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
47	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	NFKB2	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	p49/p52	_	NOUN	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	acts	_	VERB	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	concert	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	RelA	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	p65	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	HIV	_	NOUN	_	Number=Sing	_	_	_	_
22	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
25	T-leukemia	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	examine	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
6	basis	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	NFKB2	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	Scatchard	_	PROPN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
10	constants	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	homodimeric	_	ADJ	_	Degree=Pos	_	_	_	_
13	p49	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	heterodimeric	_	ADJ	_	Degree=Pos	_	_	_	_
16	p49/p65	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	SCONJ	_	_	_	_	_	_
18	binding	_	VERB	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	HIV	_	PROPN	_	Number=Sing	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	p49	_	NOUN	_	Number=Sing	_	_	_	_
2	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	approximately	_	ADV	_	_	_	_	_	_
5	18	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	fold	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
10	affinity	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	HIV	_	PROPN	_	Number=Sing	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	KD	_	NOUN	_	Number=Sing	_	_	_	_
19	=	_	SYM	_	_	_	_	_	_
20	69.1	_	NUM	_	NumType=Card	_	_	_	_
21	pM	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	than	_	SCONJ	_	_	_	_	_	_
24	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	approximately	_	ADV	_	_	_	_	_	_
27	50	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kDa	_	NOUN	_	Number=Sing	_	_	_	_
30	protein	_	NOUN	_	Number=Sing	_	_	_	_
31	NFKB1	_	PROPN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	p50	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	from	_	ADP	_	_	_	_	_	_
37	p105	_	NUM	_	NumType=Card	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	KD	_	NOUN	_	Number=Sing	_	_	_	_
40	=	_	SYM	_	_	_	_	_	_
41	3.9	_	NUM	_	NumType=Card	_	_	_	_
42	pM	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	affinity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	heterodimeric	_	ADJ	_	Degree=Pos	_	_	_	_
8	NFKB2	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	p49	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	RelA	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	p65	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	approximately	_	ADV	_	_	_	_	_	_
22	6	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
25	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	KD	_	NOUN	_	Number=Sing	_	_	_	_
28	=	_	SYM	_	_	_	_	_	_
29	11.8	_	NUM	_	NumType=Card	_	_	_	_
30	pM	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	than	_	ADP	_	_	_	_	_	_
33	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	p49	_	NOUN	_	Number=Sing	_	_	_	_
36	alone	_	ADV	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	findings	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	vitro	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	18	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	addition	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	preformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	heterodimeric	_	ADJ	_	Degree=Pos	_	_	_	_
21	NFKB2	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	p49	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	RelA	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	p65	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	protein	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	HIV	_	PROPN	_	Number=Sing	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	subject	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	recently	_	ADV	_	_	_	_	_	_
14	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	VERB	_	Number=Sing	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha	_	PROPN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	MAD	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	3	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Recombinant	_	PROPN	_	Number=Sing	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	kappa	_	VERB	_	Number=Sing	_	_	_	_
4	B	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	MAD	_	PROPN	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	3	_	X	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	DNA	_	PROPN	_	Number=Sing	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	p65	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	p49/p65	_	NOUN	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	p50/p65	_	NUM	_	Number=Sing	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	stimulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	NFKB2	_	PROPN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	p49	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	NFKB1	_	PROPN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	p50	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	reporter	_	NOUN	_	Number=Sing	_	_	_	_
7	plasmid	_	VERB	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	p49/p65	_	NUM	_	NumType=Card	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	transiently	_	ADV	_	_	_	_	_	_
12	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
14	T-leukemia	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	also	_	ADV	_	_	_	_	_	_
18	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	coexpression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	MAD	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	ABSTRACT	_	ADJ	_	Number=Sing	_	_	_	_
28	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	AT	_	ADP	_	_	_	_	_	_
30	250	_	NUM	_	NumType=Card	_	_	_	_
31	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	Document	_	NOUN	_	Number=Sing	_	_	_	_
34	003003471	_	NUM	_	NumType=Card	_	_	_	_
35	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	STATs1	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	-3	_	NUM	_	NumType=Card	_	_	_	_
9	DNA	_	NOUN	_	Number=Sing	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	arrest	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	independent	_	ADJ	_	Degree=Pos	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Lck	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	active	_	ADJ	_	Degree=Pos	_	_	_	_
20	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	T	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Type	_	NOUN	_	Number=Sing	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	interferons	_	VERB	_	Number=Plur	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	IFNs	_	NOUN	_	Number=Plur	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	family	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	antiviral	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	antiproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
17	effects	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Data	_	NOUN	_	Number=Sing	_	_	_	_
2	regarding	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	processes	_	NOUN	_	Number=Plur	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
9	transduce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	signals	_	NOUN	_	Number=Plur	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	membrane	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	becoming	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
20	increasingly	_	ADV	_	_	_	_	_	_
21	complex	_	ADJ	_	Degree=Pos	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	most	_	ADV	_	_	_	_	_	_
3	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	pathway	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	via	_	ADP	_	_	_	_	_	_
7	JAK	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	STAT	_	PROPN	_	Number=Sing	_	_	_	_
10	signaling	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	established	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	potential	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Src	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	family	_	NOUN	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	Lck	_	PROPN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	JAK	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	STAT	_	PROPN	_	Number=Sing	_	_	_	_
18	signaling	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	designed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Lck	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	IFN	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	signaling	_	VERB	_	Number=Sing	_	_	_	_
18	by	_	SCONJ	_	_	_	_	_	_
19	using	_	VERB	_	VerbForm=Ger	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	JCam	_	PROPN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	Lck	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	defective	_	ADJ	_	Degree=Pos	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	line	_	NOUN	_	Number=Sing	_	_	_	_
31	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	JCam	_	PROPN	_	Number=Sing	_	_	_	_
38	/	_	PUNCT	_	_	_	_	_	_
39	Lck	_	PROPN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	JCam	_	PROPN	_	Number=Sing	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	with	_	ADP	_	_	_	_	_	_
44	Lck	_	PROPN	_	Number=Sing	_	_	_	_
45	restored	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
10	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	only	_	ADV	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	Lck	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	STATs1	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	effectively	_	ADV	_	_	_	_	_	_
9	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
14	DNA	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	absence	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	Lck	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	IFN	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	PROPN	_	Number=Sing	_	_	_	_
10	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	antiproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
13	effect	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	all	_	DET	_	_	_	_	_	_
16	three	_	NUM	_	NumType=Card	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lines	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Lck	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	active	_	ADJ	_	Degree=Pos	_	_	_	_
8	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
9	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
12	IFN	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	growth	_	NOUN	_	Number=Sing	_	_	_	_
18	arrest	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	induction	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	STAT1s1	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	-3	_	NUM	_	NumType=Card	_	_	_	_
25	DNA	_	NOUN	_	Number=Sing	_	_	_	_
26	binding	_	VERB	_	Number=Sing	_	_	_	_
27	ability	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1999	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003473	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
5	etiology	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	palmar	_	ADJ	_	Number=Sing	_	_	_	_
8	fibromatosis	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	X	_	SYM	_	_	_	_	_	_
2	chromosome	_	NOUN	_	Degree=Pos	_	_	_	_
3	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
4	patterns	_	NOUN	_	Number=Plur	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	androgen	_	NOUN	_	Degree=Pos	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	locus	_	NOUN	_	Number=Sing	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
14	clonality	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	microdissected	_	VERB	_	Degree=Pos	_	_	_	_
17	lesional	_	ADJ	_	Degree=Pos	_	_	_	_
18	tissue	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	women	_	NOUN	_	Number=Plur	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	Dupuytren	_	PROPN	_	Number=Sing	_	_	_	_
27	's	_	PART	_	_	_	_	_	_
28	disease	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	tissue	_	NOUN	_	Number=Sing	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	both	_	DET	_	_	_	_	_	_
5	patients	_	NOUN	_	Number=Sing	_	_	_	_
6	generated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
9	pattern	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	X	_	SYM	_	_	_	_	_	_
12	chromosome	_	NOUN	_	Degree=Pos	_	_	_	_
13	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	androgen	_	NOUN	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	finding	_	NOUN	_	Number=Sing	_	_	_	_
3	supports	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
6	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
7	process	_	NOUN	_	Number=Sing	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	underlying	_	ADJ	_	Degree=Pos	_	_	_	_
11	etiology	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	palmar	_	ADJ	_	Number=Sing	_	_	_	_
14	fibromatosis	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003476	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Comparative	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	identifies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	tumor	_	NOUN	_	Number=Sing	_	_	_	_
6	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	sites	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	simian	_	PROPN	_	Number=Sing	_	_	_	_
20	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	Barr	_	PROPN	_	Number=Sing	_	_	_	_
23	virus	_	NOUN	_	Number=Sing	_	_	_	_
24	oncogene	_	PROPN	_	Number=Sing	_	_	_	_
25	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Nonhuman	_	ADJ	_	Degree=Pos	_	_	_	_
2	primates	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	naturally	_	ADV	_	_	_	_	_	_
5	infected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	lymphotropic	_	NOUN	_	Degree=Pos	_	_	_	_
11	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
12	closely	_	ADV	_	_	_	_	_	_
13	related	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	Barr	_	PROPN	_	Number=Sing	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	EBV	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	simian	_	ADJ	_	Degree=Pos	_	_	_	_
3	EBV	_	NOUN	_	Number=Sing	_	_	_	_
4	share	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	considerable	_	ADJ	_	Degree=Pos	_	_	_	_
6	genetic	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	biologic	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	epidemiologic	_	ADJ	_	Degree=Pos	_	_	_	_
12	features	_	NOUN	_	Number=Plur	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	EBV	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	including	_	VERB	_	VerbForm=Ger	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	tumorigenesis	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	latent	_	ADJ	_	Degree=Pos	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	transformation	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	associated	_	VERB	_	Degree=Pos	_	_	_	_
8	viral	_	ADJ	_	Degree=Pos	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	sequence	_	NOUN	_	Number=Sing	_	_	_	_
13	divergence	_	NOUN	_	Number=Sing	_	_	_	_
14	among	_	ADP	_	_	_	_	_	_
15	species	_	NOUN	_	Number=Plur	_	_	_	_
16	despite	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	conserved	_	VERB	_	Degree=Pos	_	_	_	_
19	functions	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	latent	_	ADJ	_	Degree=Pos	_	_	_	_
6	membrane	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	homologs	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	simian	_	ADJ	_	Degree=Pos	_	_	_	_
16	EBV	_	PROPN	_	Number=Sing	_	_	_	_
17	naturally	_	ADV	_	_	_	_	_	_
18	infecting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	baboons	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	cercopithicine	_	NOUN	_	Number=Sing	_	_	_	_
22	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
23	12	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
26	papio	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	rhesus	_	NOUN	_	Number=Sing	_	_	_	_
30	monkeys	_	NOUN	_	Number=Plur	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	cercopithicine	_	NOUN	_	Number=Sing	_	_	_	_
33	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
34	15	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	comparative	_	ADJ	_	Degree=Pos	_	_	_	_
39	study	_	NOUN	_	Number=Sing	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	human	_	ADJ	_	Degree=Pos	_	_	_	_
43	EBV	_	NOUN	_	Number=Sing	_	_	_	_
44	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transmembrane	_	NOUN	_	Number=Sing	_	_	_	_
3	domains	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	well	_	ADV	_	Degree=Pos	_	_	_	_
6	conserved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	there	_	PRON	_	_	_	_	_	_
10	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	striking	_	VERB	_	Number=Sing	_	_	_	_
12	sequence	_	NOUN	_	Number=Sing	_	_	_	_
13	divergence	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	carboxy	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
19	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
20	domain	_	NOUN	_	Number=Sing	_	_	_	_
21	essential	_	ADJ	_	Degree=Pos	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	interaction	_	NOUN	_	Number=Sing	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	tumor	_	NOUN	_	Number=Sing	_	_	_	_
32	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	receptor	_	NOUN	_	Number=Sing	_	_	_	_
35	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
36	pathway	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Nevertheless	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	simian	_	ADJ	_	Degree=Pos	_	_	_	_
5	EBV	_	PROPN	_	Number=Sing	_	_	_	_
6	LMP1s	_	PROPN	_	Number=Plur	_	_	_	_
7	retain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	most	_	ADJ	_	Degree=Sup	_	_	_	_
9	functions	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	common	_	ADJ	_	Degree=Pos	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	EBV	_	PROPN	_	Number=Sing	_	_	_	_
14	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	including	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	ability	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	B	_	NOUN	_	Degree=Pos	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	tumor	_	NOUN	_	Number=Sing	_	_	_	_
36	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
37	factor	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	factor	_	NOUN	_	Number=Sing	_	_	_	_
41	3	_	NUM	_	NumType=Card	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	TRAF3	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	vitro	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	to	_	PART	_	_	_	_	_	_
50	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
51	expression	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	tumor	_	NOUN	_	Number=Sing	_	_	_	_
54	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
55	factor	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
58	genes	_	NOUN	_	Number=Plur	_	_	_	_
59	,	_	PUNCT	_	_	_	_	_	_
60	such	_	ADJ	_	Degree=Pos	_	_	_	_
61	as	_	ADP	_	_	_	_	_	_
62	ICAM1	_	PROPN	_	Number=Sing	_	_	_	_
63	,	_	PUNCT	_	_	_	_	_	_
64	in	_	ADP	_	_	_	_	_	_
65	human	_	ADJ	_	Degree=Pos	_	_	_	_
66	B	_	NOUN	_	Number=Sing	_	_	_	_
67	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	Multiple	_	ADJ	_	Degree=Pos	_	_	_	_
2	TRAF3	_	NOUN	_	Number=Plur	_	_	_	_
3	binding	_	VERB	_	Number=Sing	_	_	_	_
4	sites	_	NOUN	_	Number=Plur	_	_	_	_
5	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	PXQXT	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	S	_	NOUN	_	Number=Sing	_	_	_	_
10	core	_	NOUN	_	Number=Sing	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	simian	_	ADJ	_	Degree=Pos	_	_	_	_
18	EBV	_	PROPN	_	Number=Sing	_	_	_	_
19	LMP	_	PROPN	_	Number=Sing	_	_	_	_
20	1s	_	NOUN	_	Number=Plur	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	vitro	_	NOUN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	assay	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	PXQXT	_	NOUN	_	Number=Sing	_	_	_	_
3	/	_	PUNCT	_	_	_	_	_	_
4	S-containing	_	NOUN	_	Number=Sing	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	present	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
12	domain	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	Hodgkin	_	PROPN	_	Number=Sing	_	_	_	_
16	's	_	PART	_	_	_	_	_	_
17	disease	_	NOUN	_	Number=Sing	_	_	_	_
18	marker	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	CD30	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	TRAF3	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vitro	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	last	_	ADJ	_	Degree=Pos	_	_	_	_
3	13	_	NUM	_	NumType=Card	_	_	_	_
4	amino	_	NOUN	_	Degree=Pos	_	_	_	_
5	acids	_	NOUN	_	Number=Plur	_	_	_	_
6	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	PXQXT	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	S	_	NOUN	_	Number=Sing	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	highly	_	ADV	_	_	_	_	_	_
14	conserved	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	simian	_	ADJ	_	Degree=Pos	_	_	_	_
19	EBV	_	PROPN	_	Number=Sing	_	_	_	_
20	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
25	TRAF3	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
30	role	_	NOUN	_	Number=Sing	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	conserved	_	VERB	_	Degree=Pos	_	_	_	_
34	region	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	conserved	_	VERB	_	Degree=Pos	_	_	_	_
3	TRAF3	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	sites	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	CD30	_	PROPN	_	Number=Sing	_	_	_	_
11	Hodgkin	_	PROPN	_	Number=Sing	_	_	_	_
12	's	_	PART	_	_	_	_	_	_
13	disease	_	NOUN	_	Number=Sing	_	_	_	_
14	marker	_	NOUN	_	Number=Sing	_	_	_	_
15	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	further	_	ADJ	_	Degree=Pos	_	_	_	_
17	evidence	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	TRAF3	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
23	signal	_	NOUN	_	Number=Sing	_	_	_	_
24	transduction	_	NOUN	_	Number=Sing	_	_	_	_
25	pathway	_	NOUN	_	Number=Sing	_	_	_	_
26	may	_	AUX	_	VerbForm=Fin	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	important	_	ADJ	_	Degree=Pos	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
31	transformation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003478	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	DR	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	nm23	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	member	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	nm23	_	NOUN	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	family	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	32Dc13	_	NUM	_	NumType=Card	_	_	_	_
27	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Chronic	_	ADJ	_	Number=Sing	_	_	_	_
2	myelogenous	_	ADJ	_	Degree=Pos	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	evolves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	clinically	_	ADV	_	_	_	_	_	_
8	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
9	stages	_	NOUN	_	Number=Plur	_	_	_	_
10	:	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	chronic	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	blast	_	ADJ	_	Degree=Pos	_	_	_	_
16	crisis	_	NOUN	_	Number=Sing	_	_	_	_
17	phase	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	changes	_	NOUN	_	Number=Plur	_	_	_	_
4	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
7	phase	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	blast	_	VERB	_	VerbForm=Inf	_	_	_	_
10	crisis	_	NOUN	_	Number=Sing	_	_	_	_
11	transition	_	NOUN	_	Number=Sing	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	largely	_	ADV	_	_	_	_	_	_
14	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
6	clone	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	DR	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	nm23	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	differentially	_	ADV	_	_	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	blast	_	ADJ	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	crisis	_	NOUN	_	Number=Sing	_	_	_	_
19	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
20	library	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	approximately	_	ADV	_	_	_	_	_	_
25	70	_	NUM	_	NumType=Card	_	_	_	_
26	%	_	SYM	_	Number=Sing	_	_	_	_
27	sequence	_	NOUN	_	Number=Sing	_	_	_	_
28	similarity	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	putative	_	ADJ	_	Degree=Pos	_	_	_	_
32	metastatic	_	ADJ	_	Degree=Pos	_	_	_	_
33	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
34	genes	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	nm23	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	H1	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	nm23	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	H2	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	deduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	amino	_	NOUN	_	Number=Sing	_	_	_	_
4	acid	_	VERB	_	Number=Sing	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	similarity	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	two	_	NUM	_	NumType=Card	_	_	_	_
14	latter	_	ADJ	_	Degree=Pos	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	approximately	_	ADV	_	_	_	_	_	_
18	65	_	NUM	_	NumType=Card	_	_	_	_
19	%	_	SYM	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	domains	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	amino	_	NOUN	_	Degree=Pos	_	_	_	_
25	acid	_	NOUN	_	Number=Sing	_	_	_	_
26	residues	_	NOUN	_	Number=Plur	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	leucine	_	NOUN	_	Number=Sing	_	_	_	_
30	zipper	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	like	_	ADP	_	Degree=Pos	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	RGD	_	PROPN	_	Number=Sing	_	_	_	_
36	domain	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	serine	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	histidine	_	NOUN	_	Degree=Pos	_	_	_	_
43	residue	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	NH2	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	COOH	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
54	portion	_	NOUN	_	Number=Sing	_	_	_	_
55	of	_	ADP	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	protein	_	NOUN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	respectively	_	ADV	_	_	_	_	_	_
60	)	_	PUNCT	_	_	_	_	_	_
61	postulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
62	to	_	PART	_	_	_	_	_	_
63	be	_	AUX	_	VerbForm=Inf	_	_	_	_
64	important	_	ADJ	_	Degree=Pos	_	_	_	_
65	for	_	ADP	_	_	_	_	_	_
66	nm23	_	NOUN	_	Number=Sing	_	_	_	_
67	function	_	NOUN	_	Number=Sing	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	DR	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	nm23	_	NOUN	_	Number=Sing	_	_	_	_
4	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	preferentially	_	ADV	_	_	_	_	_	_
7	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	at	_	ADP	_	_	_	_	_	_
9	early	_	ADJ	_	Degree=Pos	_	_	_	_
10	stages	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	highly	_	ADV	_	_	_	_	_	_
16	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	CD34	_	NOUN	_	Number=Sing	_	_	_	_
18	+	_	SYM	_	_	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
7	precursor	_	NOUN	_	Number=Sing	_	_	_	_
8	32Dc13	_	NUM	_	NumType=Card	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	growth	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	results	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
29	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
30	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
33	colony	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
36	factor	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	death	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	DR	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	nm23	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	normal	_	ADJ	_	Degree=Pos	_	_	_	_
14	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	raise	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	possibility	_	NOUN	_	Number=Sing	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
22	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	arrest	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	feature	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	blastic	_	ADJ	_	Degree=Pos	_	_	_	_
31	transformation	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	chronic	_	ADJ	_	Number=Sing	_	_	_	_
34	myelogenous	_	ADJ	_	Degree=Pos	_	_	_	_
35	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003481	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	LFA	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	Tax1	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
15	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	down	_	ADP	_	_	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	regulation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	LFA	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	adult	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	lines	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	undertaken	_	VERB	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	TaxI	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	up	_	ADP	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	LFA	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	3	_	NUM	_	NumType=Card	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	T	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	down	_	ADP	_	_	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	regulation	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	LFA	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	ATL	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
56	cell	_	NOUN	_	Number=Sing	_	_	_	_
57	lines	_	NOUN	_	Number=Plur	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TaxI	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
8	line	_	NOUN	_	Number=Sing	_	_	_	_
9	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
10	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	TaxI	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	under	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	metallothionein	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	increases	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	surface	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	response	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	LFA	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	TaxI	_	NOUN	_	Number=Sing	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	other	_	ADJ	_	Degree=Pos	_	_	_	_
15	hand	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	relatively	_	ADV	_	_	_	_	_	_
18	slow	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	weak	_	ADJ	_	Degree=Pos	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	might	_	AUX	_	VerbForm=Fin	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	indirect	_	ADJ	_	Degree=Pos	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Transactivation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	promoter	_	VERB	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	TaxI	_	PROPN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	further	_	ADV	_	_	_	_	_	_
12	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	co-transfection	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	CAT	_	NOUN	_	Number=Sing	_	_	_	_
18	reporter	_	NOUN	_	Number=Sing	_	_	_	_
19	construct	_	VERB	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	promoter	_	VERB	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	plasmid	_	ADJ	_	Number=Sing	_	_	_	_
29	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
30	TaxI	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	down	_	ADP	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	LFA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	ATL	_	NOUN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	next	_	ADV	_	_	_	_	_	_
22	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	mRNA	_	VERB	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	quite	_	ADV	_	_	_	_	_	_
7	low	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	MT	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	no	_	DET	_	_	_	_	_	_
15	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
16	changes	_	NOUN	_	Number=Plur	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CAT	_	NOUN	_	Number=Sing	_	_	_	_
3	reporter	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	MT	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	I	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	MT	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	5	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	azacytidine	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	IFN	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	gamma	_	NOUN	_	Number=Sing	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	re-expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	I.	_	PROPN	_	Number=Sing	_	_	_	_
23	Collectively	_	ADV	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	a	_	X	_	_	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	s	_	X	_	_	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	may	_	AUX	_	VerbForm=Fin	_	_	_	_
42	be	_	AUX	_	VerbForm=Inf	_	_	_	_
43	repressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	MT	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
48	through	_	ADP	_	_	_	_	_	_
49	DNA	_	PROPN	_	Number=Sing	_	_	_	_
50	methylation	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Three	_	NUM	_	NumType=Card	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	ATL	_	NOUN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	lines	_	NOUN	_	Number=Plur	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	TL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	OmI	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	H582	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	HuT102	_	NUM	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	have	_	VERB	_	VerbForm=Inf	_	_	_	_
19	little	_	ADJ	_	Degree=Pos	_	_	_	_
20	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	LFA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
26	beta	_	PROPN	_	Number=Sing	_	_	_	_
27	chain	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	CD18	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	H582	_	NOUN	_	NumType=Card	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	HuT102	_	PROPN	_	Number=Sing	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	negative	_	ADJ	_	Degree=Pos	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	LFA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	alpha	_	ADV	_	Number=Sing	_	_	_	_
13	chain	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	CDIIa	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
3	changes	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	CAT	_	NOUN	_	Number=Sing	_	_	_	_
10	reporter	_	NOUN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	CD18	_	PROPN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	again	_	ADV	_	_	_	_	_	_
25	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	lack	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	a	_	X	_	_	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	s	_	X	_	_	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	CD18	_	PROPN	_	Number=Sing	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003484	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	SOCS	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
6	phosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	response	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	STAT5	_	NOUN	_	Degree=Pos	_	_	_	_
16	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Members	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	recently	_	ADV	_	_	_	_	_	_
5	discovered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	SOCS	_	PROPN	_	Number=Plur	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	CIS	_	PROPN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	SSI	_	PROPN	_	Number=Sing	_	_	_	_
11	family	_	NOUN	_	Number=Sing	_	_	_	_
12	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	proposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	regulators	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
19	signaling	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	while	_	SCONJ	_	_	_	_	_	_
23	targets	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
26	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
28	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	some	_	DET	_	_	_	_	_	_
31	family	_	NOUN	_	Number=Sing	_	_	_	_
32	members	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	precise	_	ADJ	_	Degree=Pos	_	_	_	_
36	role	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
39	proteins	_	NOUN	_	Number=Plur	_	_	_	_
40	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	to	_	PART	_	_	_	_	_	_
42	be	_	AUX	_	VerbForm=Inf	_	_	_	_
43	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	To	_	ADP	_	_	_	_	_	_
2	date	_	NOUN	_	Number=Sing	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	SOCS	_	NOUN	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	specifically	_	ADV	_	_	_	_	_	_
9	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	SOCS	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	response	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
17	lines	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
21	blood	_	NOUN	_	Number=Sing	_	_	_	_
22	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	SOCS	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
7	as	_	ADV	_	_	_	_	_	_
8	early	_	ADV	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	30	_	NUM	_	NumType=Card	_	_	_	_
11	min	_	NOUN	_	Number=Plur	_	_	_	_
12	following	_	VERB	_	VerbForm=Ger	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	while	_	SCONJ	_	_	_	_	_	_
19	CIS	_	PROPN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	only	_	ADV	_	_	_	_	_	_
23	at	_	ADP	_	_	_	_	_	_
24	low	_	ADJ	_	Degree=Pos	_	_	_	_
25	levels	_	NOUN	_	Number=Plur	_	_	_	_
26	after	_	ADP	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	h	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Unlike	_	ADP	_	_	_	_	_	_
2	CIS	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	SOCS	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	rapidly	_	ADV	_	_	_	_	_	_
9	tyrosine	_	ADJ	_	Degree=Pos	_	_	_	_
10	phosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Tyrosine	_	PROPN	_	Number=Sing	_	_	_	_
2	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	SOCS	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	upon	_	ADP	_	_	_	_	_	_
10	coexpression	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	Jak2	_	PROPN	_	Number=Sing	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	only	_	ADV	_	_	_	_	_	_
17	weakly	_	ADV	_	_	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	SOCS	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	3	_	NUM	_	NumType=Card	_	_	_	_
8	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
14	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
18	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	markedly	_	ADV	_	_	_	_	_	_
21	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	presence	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	beta	_	PROPN	_	Number=Sing	_	_	_	_
31	chain	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2Rbeta	_	PROPN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	following	_	VERB	_	VerbForm=Ger	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	SOCS	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	3	_	NUM	_	NumType=Card	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	able	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	complex	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	particular	_	ADJ	_	Degree=Pos	_	_	_	_
30	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
31	phosphorylated	_	VERB	_	Number=Sing	_	_	_	_
32	Jak1	_	PROPN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2Rbeta	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	SOCS	_	NOUN	_	Number=Plur	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	CIS	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
19	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	STAT5b	_	PROPN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	markedly	_	ADV	_	_	_	_	_	_
24	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	while	_	SCONJ	_	_	_	_	_	_
27	there	_	PRON	_	_	_	_	_	_
28	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	only	_	ADV	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	weak	_	ADJ	_	Degree=Pos	_	_	_	_
32	effect	_	NOUN	_	Number=Sing	_	_	_	_
33	on	_	ADP	_	_	_	_	_	_
34	IL-3	_	NUM	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
37	STAT5b	_	NOUN	_	Number=Sing	_	_	_	_
38	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
39	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	3	_	NUM	_	NumType=Card	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	significantly	_	ADV	_	_	_	_	_	_
17	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	presence	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	SOCS	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	when	_	ADV	_	PronType=Int	_	_	_	_
6	SOCS	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	rapidly	_	ADV	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
21	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	responses	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	classical	_	ADJ	_	Degree=Pos	_	_	_	_
31	negative	_	ADJ	_	Degree=Pos	_	_	_	_
32	feedback	_	NOUN	_	Number=Sing	_	_	_	_
33	loop	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003490	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	LTR	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	CD40	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	CD40	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	highly	_	ADV	_	_	_	_	_	_
9	permissive	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	productive	_	ADJ	_	Degree=Pos	_	_	_	_
13	infection	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	type	_	NOUN	_	Number=Sing	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	involved	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	HIV	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	LTR	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	control	_	NOUN	_	Number=Sing	_	_	_	_
22	elements	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	virus	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	assays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
6	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	parts	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	LTR	_	PROPN	_	Number=Sing	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	reporter	_	NOUN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	essential	_	ADJ	_	Degree=Pos	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	HIV	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	LTR	_	NOUN	_	Number=Sing	_	_	_	_
33	activity	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	CD40	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
5	mobility	_	NOUN	_	Number=Sing	_	_	_	_
6	shift	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	supershift	_	NOUN	_	Number=Sing	_	_	_	_
9	assays	_	NOUN	_	Number=Plur	_	_	_	_
10	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	important	_	ADJ	_	Degree=Pos	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	composed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	at	_	ADV	_	_	_	_	_	_
21	least	_	ADV	_	Degree=Sup	_	_	_	_
22	p50	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	p65	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	subunits	_	NOUN	_	Number=Plur	_	_	_	_
32	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
33	present	_	ADJ	_	Degree=Pos	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	CD40	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	B	_	NOUN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	confirm	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	at	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
7	level	_	NOUN	_	Number=Sing	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	ability	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	B	_	ADJ	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	strongly	_	ADV	_	_	_	_	_	_
25	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003493	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
2	stress	_	NOUN	_	Number=Sing	_	_	_	_
3	triggers	_	NOUN	_	Number=Plur	_	_	_	_
4	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
5	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	translocation	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Oxidizing	_	NOUN	_	Number=Sing	_	_	_	_
2	agents	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	powerful	_	ADJ	_	Degree=Pos	_	_	_	_
5	activators	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	encoding	_	VERB	_	Number=Sing	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	involved	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	tissue	_	NOUN	_	Number=Sing	_	_	_	_
21	injury	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	evidence	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
26	catalase	_	NOUN	_	Number=Sing	_	_	_	_
27	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	previously	_	ADV	_	_	_	_	_	_
29	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
30	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	translocation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	form	_	VERB	_	VerbForm=Inf	_	_	_	_
10	sequence	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	bound	_	ADJ	_	Degree=Pos	_	_	_	_
16	complexes	_	NOUN	_	Number=Plur	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	evidenced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	immunoblotting	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	fractions	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
26	mobility	_	NOUN	_	Number=Sing	_	_	_	_
27	shift	_	NOUN	_	Number=Sing	_	_	_	_
28	assays	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	vanadate	_	NOUN	_	Number=Sing	_	_	_	_
32	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
33	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	strongly	_	ADV	_	_	_	_	_	_
36	synergize	_	VERB	_	VerbForm=Inf	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	anti-STAT3	_	ADJ	_	Degree=Pos	_	_	_	_
4	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
5	specifically	_	ADV	_	_	_	_	_	_
6	precipitated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	92	_	NUM	_	NumType=Card	_	_	_	_
11	kDa	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	becomes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	phosphorylated	_	ADJ	_	Degree=Pos	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
17	upon	_	ADP	_	_	_	_	_	_
18	lymphocyte	_	NOUN	_	Degree=Pos	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Phenylarsine	_	PROPN	_	Number=Sing	_	_	_	_
2	oxide	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
6	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	genistein	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
14	kinase	_	NOUN	_	Number=Sing	_	_	_	_
15	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	cooperated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	cancelled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	respectively	_	ADV	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	promoted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	translocation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	presented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	using	_	VERB	_	VerbForm=Ger	_	_	_	_
7	Fe2+	_	PROPN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	Cu2	_	NOUN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_

1	ions	_	NOUN	_	Number=Plur	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	that	_	PRON	_	_	_	_	_	_
4	.OH	_	AUX	_	_	_	_	_	_
5	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	Fenton	_	PROPN	_	Number=Sing	_	_	_	_
10	reactions	_	NOUN	_	Number=Plur	_	_	_	_
11	could	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	candidate	_	NOUN	_	Number=Sing	_	_	_	_
15	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
16	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
17	species	_	NOUN	_	Number=Plur	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	directly	_	ADV	_	_	_	_	_	_
20	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Present	_	ADJ	_	Degree=Pos	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	vanadate	_	NOUN	_	Number=Sing	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	likely	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
16	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
17	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	s	_	X	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
26	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	hence	_	ADV	_	_	_	_	_	_
30	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	translocation	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
11	can	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	oxidizing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	agents	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	framework	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	effects	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
27	stress	_	NOUN	_	Number=Sing	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	JAK	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	STAT	_	PROPN	_	Number=Sing	_	_	_	_
33	signaling	_	NOUN	_	Number=Sing	_	_	_	_
34	pathway	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003494	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	20	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Epi	_	PROPN	_	Number=Sing	_	_	_	_
4	analogues	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	1,25	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_

1	D3	_	PROPN	_	Number=Sing	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	highly	_	ADV	_	_	_	_	_	_
4	potent	_	ADJ	_	Degree=Pos	_	_	_	_
5	inducers	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	DRIP	_	NOUN	_	Number=Sing	_	_	_	_
8	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
9	complex	_	NOUN	_	Number=Sing	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
14	D3	_	NOUN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	1,25	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Dihydroxyvitamin	_	PROPN	_	Number=Sing	_	_	_	_
4	D3	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	1,25	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	OH	_	INTJ	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	D3	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	major	_	ADJ	_	Degree=Pos	_	_	_	_
16	role	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	bone	_	VERB	_	Degree=Pos	_	_	_	_
22	growth	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	mineralization	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	intestinal	_	ADJ	_	Degree=Pos	_	_	_	_
28	calcium	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	phosphate	_	NOUN	_	Number=Sing	_	_	_	_
31	absorption	_	NOUN	_	Number=Sing	_	_	_	_
32	;	_	PUNCT	_	_	_	_	_	_
33	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
34	also	_	ADV	_	_	_	_	_	_
35	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	as	_	ADP	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	general	_	ADJ	_	Degree=Pos	_	_	_	_
39	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
42	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	new	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	clinically	_	ADV	_	_	_	_	_	_
5	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
6	compounds	_	NOUN	_	Number=Plur	_	_	_	_
7	dissociate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	antiproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	calcemic	_	ADJ	_	Number=Sing	_	_	_	_
11	activities	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	1,25	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	OH	_	INTJ	_	_	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	2D3	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
22	basis	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
25	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
28	clearly	_	ADV	_	_	_	_	_	_
29	elucidated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	whether	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	potency	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	one	_	NUM	_	NumType=Card	_	_	_	_
10	class	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	compounds	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	20	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	epi	_	NOUN	_	Number=Sing	_	_	_	_
17	analogues	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
21	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	because	_	ADP	_	_	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	direct	_	ADJ	_	Degree=Pos	_	_	_	_
29	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
30	effects	_	NOUN	_	Number=Plur	_	_	_	_
31	on	_	ADP	_	_	_	_	_	_
32	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
33	D	_	NOUN	_	Number=Sing	_	_	_	_
34	receptor	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	VDR	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	20	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	epi	_	NOUN	_	Number=Sing	_	_	_	_
8	analogues	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	MC1627	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	MC1288	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	p21	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	Waf1	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	Cip1	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	key	_	ADJ	_	Degree=Pos	_	_	_	_
28	VDR	_	NOUN	_	Number=Sing	_	_	_	_
29	target	_	NOUN	_	Number=Sing	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	involved	_	VERB	_	Degree=Pos	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	growth	_	NOUN	_	Number=Sing	_	_	_	_
34	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	at	_	ADP	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	concentration	_	NOUN	_	Number=Sing	_	_	_	_
39	100	_	NUM	_	NumType=Card	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	fold	_	NOUN	_	VerbForm=Inf	_	_	_	_
42	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
43	than	_	ADP	_	_	_	_	_	_
44	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	1,25	_	NUM	_	NumType=Card	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	OH	_	INTJ	_	_	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	2D3	_	NUM	_	NumType=Card	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	analogue	_	VERB	_	VerbForm=Inf	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	VDR	_	NOUN	_	Number=Sing	_	_	_	_
10	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	:	_	PUNCT	_	_	_	_	_	_

1	RXR	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	GRIP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	DRIP205	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	subunit	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	DRIP	_	PROPN	_	Number=Sing	_	_	_	_
15	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
16	complex	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	interaction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	VDR	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	RXR	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	GRIP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	dose	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	most	_	ADV	_	_	_	_	_	_
20	closely	_	ADV	_	_	_	_	_	_
21	correlated	_	ADJ	_	Degree=Pos	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	ligand	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	DRIP	_	PROPN	_	Number=Sing	_	_	_	_
31	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
32	complex	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	VDR	_	PROPN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	ability	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	receptor	_	NOUN	_	Number=Sing	_	_	_	_
42	to	_	PART	_	_	_	_	_	_
43	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
44	transcription	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
47	cell	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	free	_	ADJ	_	Degree=Pos	_	_	_	_
50	system	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	compelling	_	ADJ	_	Degree=Pos	_	_	_	_
5	links	_	NOUN	_	Number=Plur	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	efficiency	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	20	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	epi	_	NOUN	_	Number=Sing	_	_	_	_
14	analogue	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	SCONJ	_	_	_	_	_	_
16	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	VDR	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	DRIP	_	NOUN	_	Number=Sing	_	_	_	_
20	interactions	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	vitro	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	ability	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
32	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
33	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003495	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Th1	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
8	responding	_	VERB	_	VerbForm=Ger	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	HBsAg	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	HBxAg	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	chronic	_	ADJ	_	Number=Sing	_	_	_	_
15	hepatitis	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	patients	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
3	pattern	_	NOUN	_	Number=Sing	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	viral	_	ADJ	_	Degree=Pos	_	_	_	_
6	antigen	_	NOUN	_	Degree=Pos	_	_	_	_
7	recognition	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	exert	_	VERB	_	VerbForm=Inf	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	profound	_	ADJ	_	Degree=Pos	_	_	_	_
14	influence	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	resolution	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	viral	_	ADJ	_	Degree=Pos	_	_	_	_
20	infections	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	viral	_	ADJ	_	Degree=Pos	_	_	_	_
23	clearance	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	initiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	whether	_	SCONJ	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	imbalance	_	NOUN	_	Number=Sing	_	_	_	_
11	oriented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	toward	_	ADP	_	_	_	_	_	_
13	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	type	_	NOUN	_	Number=Sing	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	role	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	chronic	_	ADJ	_	Number=Sing	_	_	_	_
21	hepatitis	_	NOUN	_	Number=Sing	_	_	_	_
22	B.	_	PROPN	_	Number=Sing	_	_	_	_
23	Cytokine	_	PROPN	_	Number=Sing	_	_	_	_
24	profiles	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
27	blood	_	NOUN	_	Number=Sing	_	_	_	_
28	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	chronic	_	ADJ	_	Number=Sing	_	_	_	_
33	hepatitis	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	analysed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	RT	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	PCR	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	HBsAg	_	PROPN	_	Number=Sing	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	gamma	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	4	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	10	_	NUM	_	NumType=Card	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	41	_	NUM	_	NumType=Card	_	_	_	_
27	%	_	SYM	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	8	_	NUM	_	NumType=Card	_	_	_	_
30	%	_	SYM	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	41	_	NUM	_	NumType=Card	_	_	_	_
33	%	_	SYM	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	50	_	NUM	_	NumType=Card	_	_	_	_
37	%	_	SYM	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	patients	_	NOUN	_	Number=Plur	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	respectively	_	ADV	_	_	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Among	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IFN	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	gamma	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	high	_	ADJ	_	Degree=Pos	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	serum	_	NOUN	_	Number=Sing	_	_	_	_
18	AST	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	ALT	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	could	_	AUX	_	VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	prove	_	VERB	_	VerbForm=Inf	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
11	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	protective	_	ADJ	_	Degree=Pos	_	_	_	_
14	effect	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	hepatocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	HBxAg	_	PROPN	_	Number=Sing	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	there	_	PRON	_	_	_	_	_	_
6	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	no	_	DET	_	_	_	_	_	_
8	recognizable	_	ADJ	_	Degree=Pos	_	_	_	_
9	association	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
12	patterns	_	NOUN	_	Number=Plur	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	AST	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	ALT	_	NOUN	_	Number=Sing	_	_	_	_
17	levels	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	production	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	Th1	_	NOUN	_	Number=Sing	_	_	_	_
8	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	IFN	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	gamma	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	HBsAg	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	hepatocyte	_	NOUN	_	Number=Sing	_	_	_	_
23	damage	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	chronic	_	ADJ	_	Number=Sing	_	_	_	_
26	hepatitis	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	while	_	SCONJ	_	_	_	_	_	_
30	no	_	DET	_	_	_	_	_	_
31	counteracting	_	ADJ	_	VerbForm=Ger	_	_	_	_
32	effect	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
36	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
41	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003501	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	BLR2	_	PROPN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	EBI1	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	specifically	_	ADV	_	_	_	_	_	_
11	transactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	Barr	_	PROPN	_	Number=Sing	_	_	_	_
16	virus	_	PROPN	_	Number=Sing	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	antigen	_	NOUN	_	Number=Sing	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
3	attempt	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
6	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
7	receptors	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	related	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	Burkitt	_	PROPN	_	Number=Sing	_	_	_	_
13	's	_	PART	_	_	_	_	_	_
14	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	BLR1	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
27	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	RT	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	PCR	_	NOUN	_	Number=Sing	_	_	_	_
31	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	isolation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
38	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	seven	_	NUM	_	NumType=Card	_	_	_	_
41	transmembrane	_	NOUN	_	Number=Sing	_	_	_	_
42	receptor	_	NOUN	_	Number=Sing	_	_	_	_
43	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	BLR2	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	significant	_	ADJ	_	Degree=Pos	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	similarities	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	family	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	G	_	NUM	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
16	receptors	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	turned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	out	_	ADP	_	_	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	identical	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	recently	_	ADV	_	_	_	_	_	_
26	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	EBI1	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	PROPN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	BLR2	_	PROPN	_	Number=Sing	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	could	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	highly	_	ADV	_	_	_	_	_	_
11	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	anti-CD3	_	ADJ	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
20	blood	_	NOUN	_	Number=Sing	_	_	_	_
21	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	BLR2	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
5	could	_	AUX	_	VerbForm=Fin	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	all	_	DET	_	_	_	_	_	_
10	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Barr	_	PROPN	_	Number=Sing	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	positive	_	ADJ	_	Degree=Pos	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	lines	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	BLR2	_	PROPN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	could	_	AUX	_	VerbForm=Fin	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	specifically	_	ADV	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	Barr	_	PROPN	_	Number=Sing	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	negative	_	ADJ	_	Degree=Pos	_	_	_	_
19	BL	_	PROPN	_	Number=Sing	_	_	_	_
20	41	_	NUM	_	NumType=Card	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	via	_	ADP	_	_	_	_	_	_
23	estrogen	_	ADJ	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	mediated	_	VERB	_	Degree=Pos	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	Barr	_	PROPN	_	Number=Sing	_	_	_	_
31	virus	_	NOUN	_	Number=Sing	_	_	_	_
32	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
33	antigen	_	NOUN	_	Number=Sing	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	key	_	ADJ	_	Degree=Pos	_	_	_	_
38	regulator	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	viral	_	ADJ	_	Degree=Pos	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
43	genes	_	NOUN	_	Number=Plur	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	immortalized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	B	_	ADJ	_	Number=Sing	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	involvement	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	BLR2	_	PROPN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	migration	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	viral	_	ADJ	_	Degree=Pos	_	_	_	_
19	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003502	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	roles	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	vivo	_	NOUN	_	Number=Sing	_	_	_	_
6	footprinted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	DNA	_	PROPN	_	Number=Sing	_	_	_	_
8	motifs	_	NOUN	_	Number=Plur	_	_	_	_
9	within	_	ADP	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	globin	_	NOUN	_	Number=Sing	_	_	_	_
14	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Erythroid	_	NOUN	_	Number=Sing	_	_	_	_
2	lineage	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
5	stage	_	NOUN	_	Number=Sing	_	_	_	_
6	specificities	_	NOUN	_	Number=Plur	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	like	_	ADP	_	Degree=Pos	_	_	_	_
9	globin	_	ADJ	_	Degree=Pos	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
13	zeta	_	NOUN	_	Number=Sing	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	adult	_	NOUN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	during	_	ADP	_	_	_	_	_	_
20	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
21	development	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	distal	_	ADJ	_	Degree=Pos	_	_	_	_
27	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	HS	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	40	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	DNA	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	studies	_	NOUN	_	Number=Plur	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	HS	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	40	_	NUM	_	NumType=Card	_	_	_	_
13	consists	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	binding	_	VERB	_	Number=Sing	_	_	_	_
19	motifs	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	occupied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	vivo	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
28	lineage	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
32	stage	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	specific	_	ADJ	_	Degree=Pos	_	_	_	_
35	manner	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	systematically	_	ADV	_	_	_	_	_	_
4	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	functional	_	ADJ	_	Degree=Pos	_	_	_	_
7	roles	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
12	motifs	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	HS	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	SYM	_	_	_	_	_	_
16	40	_	NUM	_	NumType=Card	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	transient	_	ADJ	_	Degree=Pos	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	assay	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	cultures	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Three	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	HS	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	40	_	NUM	_	NumType=Card	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	motifs	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	5'	_	NUM	_	NumType=Card	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	E2/AP1	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	GT	_	PROPN	_	Number=Sing	_	_	_	_
16	II	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	GATA	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	c	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	positively	_	ADV	_	_	_	_	_	_
27	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	zeta	_	NOUN	_	Number=Sing	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	globin	_	NOUN	_	Number=Sing	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	activity	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
37	/	_	PUNCT	_	_	_	_	_	_
38	fetal	_	NOUN	_	Number=Sing	_	_	_	_
39	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
40	K562	_	NUM	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	adult	_	NOUN	_	Number=Sing	_	_	_	_
45	alpha	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	globin	_	NOUN	_	Number=Sing	_	_	_	_
48	promoter	_	NOUN	_	Number=Sing	_	_	_	_
49	activity	_	NOUN	_	Number=Sing	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	adult	_	NOUN	_	Number=Sing	_	_	_	_
52	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
53	MEL	_	PROPN	_	Number=Sing	_	_	_	_
54	cells	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	hand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	3'	_	NOUN	_	NumType=Card	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	E2	_	PROPN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	AP1	_	NOUN	_	Number=Sing	_	_	_	_
13	motif	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	able	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	exert	_	VERB	_	VerbForm=Inf	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	positive	_	ADJ	_	Degree=Pos	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	negative	_	ADJ	_	Degree=Pos	_	_	_	_
22	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	effects	_	NOUN	_	Number=Plur	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	zeta	_	NOUN	_	Number=Sing	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	globin	_	NOUN	_	Degree=Pos	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	activity	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	K562	_	PROPN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
38	dual	_	ADJ	_	Degree=Pos	_	_	_	_
39	function	_	NOUN	_	Number=Sing	_	_	_	_
40	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	to	_	PART	_	_	_	_	_	_
42	be	_	AUX	_	VerbForm=Inf	_	_	_	_
43	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	through	_	ADP	_	_	_	_	_	_
45	differential	_	ADJ	_	Degree=Pos	_	_	_	_
46	binding	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
50	AP1	_	NOUN	_	Number=Sing	_	_	_	_
51	factors	_	NOUN	_	Number=Plur	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	enriched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
57	NF	_	PROPN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	E2	_	NOUN	_	Number=Sing	_	_	_	_
60	factor	_	NOUN	_	Number=Sing	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	GATA	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	d	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	motif	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	exhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	adult	_	NOUN	_	Number=Sing	_	_	_	_
16	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
20	footprint	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	decreases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	HS	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	40	_	NUM	_	NumType=Card	_	_	_	_
27	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
28	function	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	dimethyl	_	ADJ	_	Degree=Pos	_	_	_	_
31	sulfoxide	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	MEL	_	PROPN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	but	_	CCONJ	_	_	_	_	_	_
37	not	_	PART	_	_	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	K562	_	NUM	_	NumType=Card	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	defined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	roles	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	different	_	ADJ	_	Degree=Pos	_	_	_	_
11	HS	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	40	_	NUM	_	NumType=Card	_	_	_	_
14	motifs	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	remarkable	_	ADJ	_	Degree=Pos	_	_	_	_
3	correlation	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
6	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
7	data	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
11	results	_	NOUN	_	Number=Plur	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
17	lineage	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
21	stage	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	regulation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	like	_	ADJ	_	Degree=Pos	_	_	_	_
30	globin	_	NOUN	_	Degree=Pos	_	_	_	_
31	promoters	_	NOUN	_	Number=Plur	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	indeed	_	ADV	_	_	_	_	_	_
34	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	stable	_	ADJ	_	Degree=Pos	_	_	_	_
37	binding	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	specific	_	ADJ	_	Degree=Pos	_	_	_	_
40	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
41	factors	_	NOUN	_	Number=Plur	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	vivo	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003503	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	c	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	jun	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	jun	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
13	blood	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	young	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
19	adults	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	c	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	jun	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	jun	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	proto	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	oncogenes	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	PHA	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
24	blood	_	NOUN	_	Number=Sing	_	_	_	_
25	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	PBL	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	young	_	ADJ	_	Degree=Pos	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	aged	_	ADJ	_	Degree=Pos	_	_	_	_
33	humans	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Specific	_	ADJ	_	Degree=Pos	_	_	_	_
2	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	fos	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	jun	_	NOUN	_	Number=Sing	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
13	within	_	ADP	_	_	_	_	_	_
14	30	_	NUM	_	NumType=Card	_	_	_	_
15	min	_	NOUN	_	Number=Plur	_	_	_	_
16	after	_	ADP	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	reached	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
22	levels	_	NOUN	_	Number=Plur	_	_	_	_
23	within	_	ADP	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	h	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	jun	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
7	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	pre-activation	_	NOUN	_	Number=Sing	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	6	_	NUM	_	NumType=Card	_	_	_	_
13	h	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	while	_	SCONJ	_	_	_	_	_	_
16	c	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	jun	_	NOUN	_	Number=Sing	_	_	_	_
19	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
20	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	elevated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	PHA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	PBL	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	no	_	DET	_	_	_	_	_	_
8	age	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	related	_	ADJ	_	Degree=Pos	_	_	_	_
11	differences	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	c	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	fos	_	NOUN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	jun	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	c-jun	_	VERB	_	Degree=Pos	_	_	_	_
4	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	significantly	_	ADV	_	_	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	1.73	_	NUM	_	NumType=Card	_	_	_	_
10	+/-	_	SYM	_	_	_	_	_	_
11	0.08	_	NUM	_	NumType=Card	_	_	_	_
12	vs.	_	ADP	_	_	_	_	_	_
13	1.16	_	NUM	_	NumType=Card	_	_	_	_
14	+/-	_	SYM	_	_	_	_	_	_
15	0.09	_	NUM	_	NumType=Card	_	_	_	_
16	arbitrary	_	ADJ	_	Degree=Pos	_	_	_	_
17	units	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	P	_	NOUN	_	Number=Sing	_	_	_	_
20	<	_	PUNCT	_	_	_	_	_	_
21	0.01	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	young	_	ADJ	_	Degree=Pos	_	_	_	_
24	vs.	_	ADP	_	_	_	_	_	_
25	old	_	ADJ	_	Degree=Pos	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	PBL	_	NOUN	_	Number=Sing	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
31	individuals	_	NOUN	_	Number=Plur	_	_	_	_
32	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	PHA	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	previous	_	ADJ	_	Degree=Pos	_	_	_	_
3	work	_	NOUN	_	Number=Sing	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
11	individuals	_	NOUN	_	Number=Plur	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	display	_	VERB	_	VerbForm=Inf	_	_	_	_
14	normal	_	ADJ	_	Degree=Pos	_	_	_	_
15	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
16	responses	_	NOUN	_	Number=Plur	_	_	_	_
17	when	_	ADV	_	PronType=Int	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	via	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	anti-CD2	_	NOUN	_	Number=Sing	_	_	_	_
22	pathway	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	c	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	jun	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	jun	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
33	also	_	ADV	_	_	_	_	_	_
34	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	anti-CD2	_	ADJ	_	NumType=Card	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	T	_	NOUN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	age	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	related	_	ADJ	_	Degree=Pos	_	_	_	_
5	differences	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	either	_	DET	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	proto	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	anti-CD2	_	ADJ	_	Number=Sing	_	_	_	_
21	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	production	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	displayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	PHA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	PBL	_	NOUN	_	Number=Sing	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
22	adults	_	NOUN	_	Number=Plur	_	_	_	_
23	may	_	AUX	_	VerbForm=Fin	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	related	_	ADJ	_	Degree=Pos	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	age	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	related	_	ADJ	_	Degree=Pos	_	_	_	_
30	changes	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	c	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	jun	_	NOUN	_	Number=Sing	_	_	_	_
35	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	ratio	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	c	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	fos	_	ADP	_	Number=Sing	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	c	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	jun	_	NOUN	_	Number=Sing	_	_	_	_
49	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003506	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Lineage	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	interferon	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	gamma	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	interferon	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	gamma	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	gamma	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	heterodimeric	_	ADJ	_	Degree=Pos	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	induces	_	VERB	_	Number=Plur	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
20	kinases	_	NOUN	_	Number=Plur	_	_	_	_
21	JAK1	_	PROPN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	JAK2	_	PROPN	_	Number=Sing	_	_	_	_
24	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	STAT1alpha	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Selective	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	STAT1alpha	_	PROPN	_	Number=Sing	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	gamma	_	NOUN	_	Number=Sing	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	achieved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	interaction	_	NOUN	_	Number=Sing	_	_	_	_
16	between	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
19	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
20	motif	_	NOUN	_	Number=Sing	_	_	_	_
21	including	_	VERB	_	VerbForm=Ger	_	_	_	_
22	Y440	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	IFN	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	gamma	_	NOUN	_	Number=Sing	_	_	_	_
28	receptor	_	NOUN	_	Number=Sing	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	chain	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	SH2	_	NOUN	_	Number=Sing	_	_	_	_
35	domain	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	STAT1alpha	_	PROPN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	addition	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	STAT1alpha	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	IFN	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	gamma	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	HL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	60	_	NUM	_	NumType=Card	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	although	_	SCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	type	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	IFN	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	gamma	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	differentiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	vitro	_	NOUN	_	Number=Sing	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	CD34	_	NOUN	_	Number=Sing	_	_	_	_
26	+	_	SYM	_	_	_	_	_	_
27	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
28	stem	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	single	_	ADJ	_	Degree=Pos	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	different	_	ADJ	_	Degree=Pos	_	_	_	_
12	STAT	_	PROPN	_	Number=Sing	_	_	_	_
13	family	_	NOUN	_	Number=Sing	_	_	_	_
14	members	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	manner	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	might	_	AUX	_	VerbForm=Fin	_	_	_	_
24	result	_	VERB	_	VerbForm=Inf	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	specific	_	ADJ	_	Degree=Pos	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003508	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	purification	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	Stat	_	PROPN	_	Number=Sing	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	key	_	ADJ	_	Degree=Pos	_	_	_	_
3	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	during	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	immune	_	ADJ	_	Degree=Pos	_	_	_	_
8	response	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_
14	Following	_	VERB	_	VerbForm=Ger	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	various	_	ADJ	_	Degree=Pos	_	_	_	_
28	chains	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	receptor	_	NOUN	_	Number=Sing	_	_	_	_
32	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	transcriptionally	_	ADV	_	_	_	_	_	_
34	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	turn	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	serves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	recent	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	implicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	Jak	_	PROPN	_	Number=Sing	_	_	_	_
7	kinases	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	signaling	_	NOUN	_	Number=Sing	_	_	_	_
11	pathway	_	NOUN	_	Number=Sing	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_
18	Following	_	VERB	_	VerbForm=Ger	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	lead	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
23	set	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	out	_	ADP	_	_	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	response	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
3	blood	_	NOUN	_	Number=Sing	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
9	several	_	ADJ	_	Degree=Pos	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
15	DNA	_	NOUN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	activities	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	activities	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	YT	_	PRON	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	activities	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	principal	_	ADJ	_	Degree=Pos	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
16	component	_	NOUN	_	Number=Sing	_	_	_	_
17	bears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	significant	_	ADJ	_	Degree=Pos	_	_	_	_
19	relatedness	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	prolactin	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	first	_	ADV	_	_	_	_	_	_
28	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	sheep	_	NOUN	_	Number=Plur	_	_	_	_
31	mammary	_	NOUN	_	Number=Sing	_	_	_	_
32	gland	_	NOUN	_	Number=Sing	_	_	_	_
33	tissue	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	hypothesize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	DET	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	hStat5	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	helps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	govern	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	biological	_	ADJ	_	Degree=Pos	_	_	_	_
16	effects	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	during	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	immune	_	ADJ	_	Degree=Pos	_	_	_	_
24	response	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003514	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
2	acid	_	ADJ	_	Number=Sing	_	_	_	_
3	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	interferon	_	NOUN	_	Number=Sing	_	_	_	_
5	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	trans-retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
4	acid	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	drug	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	choice	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	treatment	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	acute	_	ADJ	_	Degree=Pos	_	_	_	_
18	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	APL	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
2	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	both	_	CCONJ	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	vitro	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	vivo	_	ADJ	_	Number=Sing	_	_	_	_
9	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	APL	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	into	_	ADP	_	_	_	_	_	_
14	mature	_	ADJ	_	Degree=Pos	_	_	_	_
15	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
6	involved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	growth	_	NOUN	_	Number=Sing	_	_	_	_
12	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	presently	_	ADV	_	_	_	_	_	_
19	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NB4	_	PROPN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	line	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	derived	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	bone	_	NOUN	_	Number=Sing	_	_	_	_
12	marrow	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	patient	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	APL	_	NOUN	_	Number=Sing	_	_	_	_
18	during	_	ADP	_	_	_	_	_	_
19	relapse	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	can	_	AUX	_	VerbForm=Fin	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	model	_	NOUN	_	Number=Sing	_	_	_	_
27	system	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	study	_	VERB	_	VerbForm=Inf	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	growth	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	APL	_	NOUN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	interferon	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	IFN	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	IRF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	IRF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	IFN	_	ADJ	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	products	_	NOUN	_	Number=Plur	_	_	_	_
24	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	growth	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
29	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	effects	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
34	on	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
39	genes	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
5	directly	_	ADV	_	_	_	_	_	_
6	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	IRF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	IRF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	'	_	NOUN	_	Number=Plur	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	5'	_	NUM	_	NumType=Card	_	_	_	_
25	oligoadenylate	_	ADJ	_	Degree=Pos	_	_	_	_
26	synthetase	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	OAS	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	slower	_	ADJ	_	Degree=Cmp	_	_	_	_
34	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	NB4	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	IRF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	HL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	60	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	U937	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	THP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	all	_	DET	_	_	_	_	_	_
30	respond	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	growth	_	NOUN	_	Number=Sing	_	_	_	_
35	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	more	_	ADJ	_	Degree=Cmp	_	_	_	_
3	than	_	ADP	_	_	_	_	_	_
4	additive	_	ADJ	_	Degree=Pos	_	_	_	_
5	increase	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	IRF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	IFN	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	gamma	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	NB4	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
2	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	transducer	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	activator	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	STAT	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	pathways	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	alternate	_	ADJ	_	Degree=Pos	_	_	_	_
26	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	involved	_	ADJ	_	Degree=Pos	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	IRF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IRF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	activator	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	repressor	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	transformation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	one	_	NUM	_	NumType=Card	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
26	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	growth	_	NOUN	_	Number=Sing	_	_	_	_
32	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	basis	_	NOUN	_	Number=Sing	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
40	actions	_	NOUN	_	Number=Plur	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	ATRA	_	NOUN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	IFNs	_	NOUN	_	Number=Plur	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
47	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003516	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	localization	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	p50	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	p52	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	RelB	_	NOUN	_	Number=Sing	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	accessory	_	ADJ	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	immune	_	ADJ	_	Degree=Pos	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	situ	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Rel	_	PROPN	_	Number=Sing	_	_	_	_
3	/	_	PUNCT	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	p50	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	p52	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	p65	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	c	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	Rel	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	RelB	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	constitute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	family	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	involved	_	ADJ	_	Degree=Pos	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	positive	_	ADJ	_	Degree=Pos	_	_	_	_
33	regulation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	variety	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	genes	_	NOUN	_	Number=Plur	_	_	_	_
39	during	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	immune	_	ADJ	_	Degree=Pos	_	_	_	_
42	response	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
6	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	RelB	_	PROPN	_	Number=Sing	_	_	_	_
9	knockout	_	NOUN	_	Number=Sing	_	_	_	_
10	mice	_	NOUN	_	Number=Plur	_	_	_	_
11	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	no	_	DET	_	_	_	_	_	_
13	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	DC	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p50	_	NOUN	_	Number=Sing	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
10	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	FDC	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
3	NF	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	mature	_	ADJ	_	Degree=Pos	_	_	_	_
13	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	some	_	DET	_	_	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	Rel	_	PROPN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	key	_	ADJ	_	Degree=Pos	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	factors	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	functions	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	accessory	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	immune	_	ADJ	_	Degree=Pos	_	_	_	_
29	response	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	situ	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	localization	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Rel	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	accessory	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	immune	_	ADJ	_	Number=Sing	_	_	_	_
24	system	_	NOUN	_	Number=Sing	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	immunohistochemistry	_	ADJ	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	double	_	ADJ	_	Degree=Pos	_	_	_	_
29	labeling	_	NOUN	_	Number=Sing	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	five	_	NUM	_	NumType=Card	_	_	_	_
34	normal	_	ADJ	_	Degree=Pos	_	_	_	_
35	human	_	ADJ	_	Degree=Pos	_	_	_	_
36	tonsils	_	NOUN	_	Number=Plur	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	five	_	NUM	_	NumType=Card	_	_	_	_
39	lymph	_	NOUN	_	Number=Sing	_	_	_	_
40	nodes	_	NOUN	_	Number=Plur	_	_	_	_
41	with	_	ADP	_	_	_	_	_	_
42	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
43	hyperplasia	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	p65	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	Rel	_	NOUN	_	Number=Sing	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	all	_	DET	_	_	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	types	_	NOUN	_	Number=Plur	_	_	_	_
14	including	_	VERB	_	VerbForm=Ger	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	germinal	_	ADJ	_	Degree=Pos	_	_	_	_
3	centers	_	NOUN	_	Number=Plur	_	_	_	_
4	GC	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	p50	_	NUM	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	p52	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	RelB	_	NOUN	_	Number=Sing	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	FDC	_	PROPN	_	Number=Sing	_	_	_	_
19	only	_	ADV	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	CD68	_	NOUN	_	Number=Sing	_	_	_	_
29	+	_	SYM	_	_	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	T	_	NUM	_	NumType=Card	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	areas	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	p50	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	p52	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	RelB	_	NOUN	_	Number=Sing	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	HLA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	DR	_	NOUN	_	Number=Sing	_	_	_	_
21	+	_	SYM	_	_	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	antigen	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	presenting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	APC	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	morphology	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	p52	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	RelB	_	PROPN	_	Number=Sing	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	CD1a	_	PROPN	_	Number=Sing	_	_	_	_
12	+	_	SYM	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	CD68	_	NOUN	_	Number=Sing	_	_	_	_
15	+	_	SYM	_	_	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	area	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	whereas	_	SCONJ	_	_	_	_	_	_
24	p50	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	only	_	ADV	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	CD68	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	CD1a	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Cells	_	NOUN	_	Number=Plur	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	p50	_	NOUN	_	Number=Sing	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	negative	_	ADJ	_	Degree=Pos	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	CD38	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	CD20	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	CD2	_	NOUN	_	Number=Sing	_	_	_	_
14	markers	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	physiologically	_	ADV	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	high	_	ADJ	_	Degree=Pos	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	nuclear	_	NOUN	_	Degree=Pos	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	p50	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	p52	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	RelB	_	NOUN	_	Number=Sing	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	accessory	_	VERB	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	immune	_	NOUN	_	Number=Sing	_	_	_	_
26	system	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	FDC	_	PROPN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	GC	_	PROPN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	DC	_	PROPN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	T	_	PROPN	_	Number=Sing	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	zone	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	that	_	DET	_	PronType=Rel	_	_	_	_
45	specialized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	scavenger	_	NOUN	_	Number=Sing	_	_	_	_
47	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
48	from	_	ADP	_	_	_	_	_	_
49	GC	_	PROPN	_	Number=Sing	_	_	_	_
50	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
51	not	_	PART	_	_	_	_	_	_
52	have	_	VERB	_	VerbForm=Inf	_	_	_	_
53	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
54	levels	_	NOUN	_	Number=Plur	_	_	_	_
55	of	_	ADP	_	_	_	_	_	_
56	p52	_	NOUN	_	Number=Sing	_	_	_	_
57	and	_	CCONJ	_	_	_	_	_	_
58	RelB	_	NOUN	_	Number=Sing	_	_	_	_
59	,	_	PUNCT	_	_	_	_	_	_
60	whereas	_	SCONJ	_	_	_	_	_	_
61	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
62	from	_	ADP	_	_	_	_	_	_
63	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
64	T	_	PROPN	_	Number=Sing	_	_	_	_
65	cell	_	NOUN	_	Number=Sing	_	_	_	_
66	area	_	NOUN	_	Number=Sing	_	_	_	_
67	,	_	PUNCT	_	_	_	_	_	_
68	known	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
69	to	_	PART	_	_	_	_	_	_
70	present	_	VERB	_	VerbForm=Inf	_	_	_	_
71	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
72	antigen	_	NOUN	_	Number=Sing	_	_	_	_
73	to	_	ADP	_	_	_	_	_	_
74	T	_	PROPN	_	Number=Sing	_	_	_	_
75	cells	_	NOUN	_	Number=Plur	_	_	_	_
76	,	_	PUNCT	_	_	_	_	_	_
77	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
78	have	_	VERB	_	VerbForm=Inf	_	_	_	_
79	both	_	CCONJ	_	_	_	_	_	_
80	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
81	p52	_	NOUN	_	Number=Sing	_	_	_	_
82	and	_	CCONJ	_	_	_	_	_	_
83	RelB	_	NOUN	_	Number=Sing	_	_	_	_
84	,	_	PUNCT	_	_	_	_	_	_
85	and	_	CCONJ	_	_	_	_	_	_
86	that	_	SCONJ	_	_	_	_	_	_
87	in	_	ADP	_	_	_	_	_	_
88	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
89	T	_	NOUN	_	Number=Sing	_	_	_	_
90	cell	_	NOUN	_	Number=Sing	_	_	_	_
91	zone	_	NOUN	_	Number=Sing	_	_	_	_
92	,	_	PUNCT	_	_	_	_	_	_
93	p52	_	NOUN	_	Number=Sing	_	_	_	_
94	and	_	CCONJ	_	_	_	_	_	_
95	RelB	_	PROPN	_	Number=Sing	_	_	_	_
96	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
97	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
98	in	_	ADP	_	_	_	_	_	_
99	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
100	of	_	ADP	_	_	_	_	_	_
101	both	_	CCONJ	_	_	_	_	_	_
102	CD1a	_	PROPN	_	Number=Sing	_	_	_	_
103	+	_	SYM	_	_	_	_	_	_
104	,	_	PUNCT	_	_	_	_	_	_
105	CD68	_	NOUN	_	Number=Sing	_	_	_	_
106	+	_	SYM	_	_	_	_	_	_
107	or	_	CCONJ	_	_	_	_	_	_
108	both	_	DET	_	_	_	_	_	_
109	,	_	PUNCT	_	_	_	_	_	_
110	cells	_	NOUN	_	Number=Plur	_	_	_	_
111	APC	_	PROPN	_	Number=Sing	_	_	_	_
112	,	_	PUNCT	_	_	_	_	_	_
113	whereas	_	SCONJ	_	_	_	_	_	_
114	p50	_	NOUN	_	Number=Sing	_	_	_	_
115	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
116	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
117	to	_	ADP	_	_	_	_	_	_
118	CD1a	_	PROPN	_	Number=Sing	_	_	_	_
119	-	_	PUNCT	_	_	_	_	_	_
120	and	_	CCONJ	_	_	_	_	_	_
121	CD68	_	PROPN	_	Number=Sing	_	_	_	_
122	-	_	PUNCT	_	_	_	_	_	_
123	APC	_	PROPN	_	Number=Sing	_	_	_	_
124	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	different	_	ADJ	_	Degree=Pos	_	_	_	_
3	patterns	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	p50	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	p52	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	RelB	_	PROPN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	localization	_	NOUN	_	Number=Sing	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
15	insight	_	NOUN	_	Number=Sing	_	_	_	_
16	into	_	ADP	_	_	_	_	_	_
17	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	different	_	ADJ	_	Degree=Pos	_	_	_	_
19	roles	_	NOUN	_	Number=Plur	_	_	_	_
20	during	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	immune	_	ADJ	_	Degree=Pos	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	vivo	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003523	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	subunit	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	GC	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
12	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	functions	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	effect	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	DM	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	T	_	NOUN	_	NumType=Card	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	receptor	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	2R	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	generation	_	NOUN	_	Number=Sing	_	_	_	_
40	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Dexamethasone	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Number=Sing	_	_	_	_

1	T	_	NUM	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	30	_	NUM	_	NumType=Card	_	_	_	_
6	%	_	SYM	_	Number=Sing	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	88	_	NUM	_	NumType=Card	_	_	_	_
9	%	_	SYM	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	relative	_	ADV	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	concentration	_	NOUN	_	Number=Sing	_	_	_	_
15	within	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	cultures	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	DM	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2R	_	NOUN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	Tac	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	p55	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	CD25	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	beta	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	p75	_	NUM	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	next	_	ADV	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	PHA	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	p	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	beta-phorbol	_	NOUN	_	Number=Sing	_	_	_	_
16	12	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	myristate	_	NOUN	_	Number=Sing	_	_	_	_
19	13	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	acetate	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	PMA	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	addition	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	DM	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	cultures	_	NOUN	_	Number=Plur	_	_	_	_
31	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	60	_	NUM	_	NumType=Card	_	_	_	_
35	%	_	SYM	_	Number=Sing	_	_	_	_
36	reduction	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	IL	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	2R	_	NOUN	_	Number=Sing	_	_	_	_
41	alpha	_	NOUN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	30	_	NUM	_	NumType=Card	_	_	_	_
45	%	_	SYM	_	Number=Sing	_	_	_	_
46	reduction	_	NOUN	_	Number=Sing	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	IL	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	2R	_	NUM	_	NumType=Card	_	_	_	_
51	beta	_	NOUN	_	Number=Sing	_	_	_	_
52	membrane	_	NOUN	_	Number=Sing	_	_	_	_
53	expression	_	NOUN	_	Number=Sing	_	_	_	_
54	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
55	to	_	ADP	_	_	_	_	_	_
56	T	_	PROPN	_	Number=Sing	_	_	_	_
57	cells	_	NOUN	_	Number=Plur	_	_	_	_
58	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
59	in	_	ADP	_	_	_	_	_	_
60	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
61	absence	_	NOUN	_	Number=Sing	_	_	_	_
62	of	_	ADP	_	_	_	_	_	_
63	DM	_	NOUN	_	Number=Sing	_	_	_	_
64	(	_	PUNCT	_	_	_	_	_	_
65	p	_	NOUN	_	Number=Sing	_	_	_	_
66	<	_	PUNCT	_	_	_	_	_	_
67	0.01	_	NUM	_	NumType=Card	_	_	_	_
68	)	_	PUNCT	_	_	_	_	_	_
69	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	membrane	_	NOUN	_	Number=Sing	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2R	_	PROPN	_	Number=Sing	_	_	_	_
7	alpha	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2R	_	NUM	_	NumType=Card	_	_	_	_
12	beta	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	10	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	6	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	M	_	PROPN	_	NumType=Card	_	_	_	_
21	DM	_	PROPN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	partially	_	ADV	_	_	_	_	_	_
24	reversible	_	ADJ	_	Degree=Pos	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	rhIL	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
3	blot	_	PROPN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	DM	_	PROPN	_	Number=Sing	_	_	_	_
7	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
10	decrease	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2R	_	PROPN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2R	_	NUM	_	NumType=Card	_	_	_	_
21	beta	_	NOUN	_	Number=Sing	_	_	_	_
22	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	membrane	_	VERB	_	VerbForm=Inf	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	mitogen	_	ADJ	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	vitro	_	NOUN	_	Number=Sing	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	DM	_	PROPN	_	Number=Sing	_	_	_	_
8	regulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2R	_	NUM	_	NumType=Card	_	_	_	_
12	alpha	_	PROPN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	level	_	NOUN	_	Number=Sing	_	_	_	_
19	while	_	SCONJ	_	_	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2R	_	NUM	_	Number=Sing	_	_	_	_
25	beta	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	unaffected	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	DM	_	PROPN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	action	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	DM	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2R	_	NOUN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	SCONJ	_	_	_	_	_	_
16	determining	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
19	levels	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	p50	_	NUM	_	Number=Sing	_	_	_	_
23	subunit	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	PROPN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	factor	_	NOUN	_	Number=Sing	_	_	_	_
39	that	_	PRON	_	PronType=Rel	_	_	_	_
40	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	2R	_	NUM	_	NumType=Card	_	_	_	_
44	alpha	_	NOUN	_	Number=Sing	_	_	_	_
45	gene	_	NOUN	_	Number=Sing	_	_	_	_
46	expression	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	10	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	M	_	NOUN	_	NumType=Card	_	_	_	_
11	DM	_	PROPN	_	Number=Sing	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	p50	_	NUM	_	NumType=Card	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
21	levels	_	NOUN	_	Number=Plur	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	four	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	fold	_	NOUN	_	Number=Sing	_	_	_	_
26	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	levels	_	NOUN	_	Number=Plur	_	_	_	_
30	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	absence	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	DM	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	level	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	capable	_	ADJ	_	Degree=Pos	_	_	_	_
9	of	_	SCONJ	_	_	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	sites	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	response	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	DM	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	sum	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	DM	_	PROPN	_	Number=Sing	_	_	_	_
5	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	membrane	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2R	_	NUM	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	more	_	ADJ	_	Degree=Cmp	_	_	_	_
16	than	_	ADP	_	_	_	_	_	_
17	one	_	NUM	_	NumType=Card	_	_	_	_
18	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
19	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003528	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	patients	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	lupus	_	NOUN	_	Number=Sing	_	_	_	_
7	nephritis	_	NOUN	_	Number=Sing	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	relationship	_	NOUN	_	Number=Sing	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	effect	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
20	therapy	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
5	significance	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	determination	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	20	_	NUM	_	NumType=Card	_	_	_	_
12	patients	_	NOUN	_	Number=Plur	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	systemic	_	ADJ	_	Degree=Pos	_	_	_	_
15	lupus	_	NOUN	_	Number=Sing	_	_	_	_
16	erythematosus	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	SLE	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	who	_	PRON	_	PronType=Rel	_	_	_	_
21	afterwards	_	ADV	_	_	_	_	_	_
22	developed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	nephrotic	_	ADJ	_	Degree=Pos	_	_	_	_
24	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	MNL	_	X	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	patients	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	both	_	DET	_	_	_	_	_	_
19	other	_	ADJ	_	Degree=Pos	_	_	_	_
20	patients	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	SLE	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
25	persons	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Improvement	_	NOUN	_	Number=Sing	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	urinary	_	ADJ	_	Degree=Pos	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	excretion	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	disease	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	scored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	according	_	VERB	_	VerbForm=Ger	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	SLE	_	PROPN	_	Number=Sing	_	_	_	_
18	Disease	_	PROPN	_	Number=Sing	_	_	_	_
19	Activity	_	NOUN	_	Number=Sing	_	_	_	_
20	Index	_	NOUN	_	Number=Sing	_	_	_	_
21	system	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	University	_	PROPN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	Toronto	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	closely	_	ADV	_	_	_	_	_	_
29	related	_	ADJ	_	Degree=Pos	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
33	receptor	_	NOUN	_	Number=Sing	_	_	_	_
34	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	MNL	_	PROPN	_	Number=Sing	_	_	_	_
37	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	from	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	corresponding	_	VERB	_	Degree=Pos	_	_	_	_
41	patients	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	summary	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	determination	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	patients	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	lupus	_	NOUN	_	Number=Sing	_	_	_	_
11	nephritis	_	NOUN	_	Number=Sing	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	predictive	_	ADJ	_	Degree=Pos	_	_	_	_
16	clue	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	SCONJ	_	_	_	_	_	_
18	assessing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
22	therapy	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003533	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	rel	_	PROPN	_	Number=Sing	_	_	_	_

1	Is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
2	rapidly	_	ADV	_	_	_	_	_	_
3	tyrosine	_	ADJ	_	Degree=Pos	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	following	_	VERB	_	VerbForm=Ger	_	_	_	_
7	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	colony	_	NOUN	_	Number=Sing	_	_	_	_
10	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	treatment	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	colony	_	NOUN	_	Number=Sing	_	_	_	_
8	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	G	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	CSF	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	results	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	respiratory	_	NOUN	_	Number=Sing	_	_	_	_
20	burst	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	prolonged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	survival	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	tumor	_	NOUN	_	Number=Sing	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	killing	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	G	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	CSF	_	NOUN	_	Number=Sing	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	SCONJ	_	_	_	_	_	_
10	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	high	_	ADJ	_	Degree=Pos	_	_	_	_
15	affinity	_	NOUN	_	Number=Sing	_	_	_	_
16	receptors	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	G-CSF	_	NOUN	_	Number=Sing	_	_	_	_
2	receptors	_	NOUN	_	Number=Plur	_	_	_	_
3	lack	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	intrinsic	_	ADJ	_	Degree=Pos	_	_	_	_
5	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	results	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
21	kinase	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Antiphosphotyrosine	_	DET	_	Degree=Pos	_	_	_	_
2	immunoblots	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	whole	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	lysates	_	NOUN	_	Number=Plur	_	_	_	_
7	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
10	show	_	VERB	_	Number=Sing	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	G-CSF	_	NOUN	_	Number=Sing	_	_	_	_
14	rapidly	_	ADV	_	_	_	_	_	_
15	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	prominent	_	ADJ	_	Degree=Pos	_	_	_	_
17	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
18	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	relative	_	ADJ	_	Degree=Pos	_	_	_	_
25	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
26	mass	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	80	_	NUM	_	NumType=Card	_	_	_	_
29	kDa	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	monospecific	_	ADJ	_	Degree=Pos	_	_	_	_
3	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	80	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kDa	_	NOUN	_	Number=Sing	_	_	_	_
9	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
15	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	p80c	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	rel	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	proto	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
26	belonging	_	VERB	_	VerbForm=Ger	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	family	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
32	regulators	_	NOUN	_	Number=Plur	_	_	_	_
33	which	_	PRON	_	PronType=Rel	_	_	_	_
34	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kB	_	PROPN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	p80c	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	rel	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	unique	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	G	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	CSF	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
18	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
21	colony	_	NOUN	_	Number=Sing	_	_	_	_
22	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	also	_	ADV	_	_	_	_	_	_
26	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	induces	_	VERB	_	Number=Plur	_	_	_	_
30	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
31	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
32	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	not	_	PART	_	_	_	_	_	_
34	result	_	VERB	_	VerbForm=Inf	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
37	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	p80c	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	rel	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	consequences	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p80c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	rel	_	NOUN	_	Number=Sing	_	_	_	_
7	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
8	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	yet	_	ADV	_	_	_	_	_	_
12	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	;	_	PUNCT	_	_	_	_	_	_
14	however	_	ADV	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	p80c	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	rel	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	capable	_	ADJ	_	Degree=Pos	_	_	_	_
24	of	_	SCONJ	_	_	_	_	_	_
25	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	DNA	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	G-CSF	_	NOUN	_	Number=Sing	_	_	_	_
31	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
32	results	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	increase	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	amount	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	p80c	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	rel	_	NOUN	_	Number=Sing	_	_	_	_
43	which	_	PRON	_	PronType=Rel	_	_	_	_
44	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	DNA	_	PROPN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	one	_	NUM	_	NumType=Card	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
9	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
10	events	_	NOUN	_	Number=Plur	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
15	following	_	VERB	_	VerbForm=Ger	_	_	_	_
16	G	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	CSF	_	NOUN	_	Number=Sing	_	_	_	_
19	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
25	kinase	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	directly	_	ADV	_	_	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
32	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	p80c	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	rel	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	G	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CSF	_	PROPN	_	Number=Sing	_	_	_	_
11	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	directly	_	ADV	_	_	_	_	_	_
14	transduce	_	VERB	_	VerbForm=Inf	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	signal	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	which	_	DET	_	PronType=Rel	_	_	_	_
21	functions	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	regulator	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003538	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	relies	_	NOUN	_	Number=Plur	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	Janus	_	PROPN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	function	_	NOUN	_	Number=Sing	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
18	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	can	_	AUX	_	VerbForm=Fin	_	_	_	_
22	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	both	_	DET	_	_	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	regulation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	consequences	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	through	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	4R	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	functionally	_	ADV	_	_	_	_	_	_
3	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	mutants	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	murine	_	NOUN	_	Number=Sing	_	_	_	_
9	pro-B	_	NOUN	_	NumType=Card	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	Ba	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	F3	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	could	_	AUX	_	VerbForm=Fin	_	_	_	_
18	show	_	VERB	_	VerbForm=Inf	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	phosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
21	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
22	residues	_	NOUN	_	Number=Plur	_	_	_	_
23	within	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	4R	_	PROPN	_	Number=Sing	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	chain	_	NOUN	_	Number=Sing	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	dispensable	_	ADJ	_	Degree=Pos	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	4	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
39	activity	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	disruption	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	membrane	_	ADJ	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
9	proline	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	rich	_	ADJ	_	Degree=Pos	_	_	_	_
12	sequence	_	NOUN	_	Number=Sing	_	_	_	_
13	motif	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	'	_	PUNCT	_	_	_	_	_	_
16	box1	_	NOUN	_	Number=Sing	_	_	_	_
17	'	_	PUNCT	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	either	_	CCONJ	_	_	_	_	_	_
21	subunit	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	bipartite	_	ADJ	_	Degree=Pos	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	4R	_	NOUN	_	Number=Sing	_	_	_	_
28	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	not	_	ADV	_	_	_	_	_	_
30	only	_	ADV	_	_	_	_	_	_
31	ligand	_	ADJ	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
35	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	Janus	_	PROPN	_	Number=Sing	_	_	_	_
38	kinases	_	NOUN	_	Number=Plur	_	_	_	_
39	JAK1	_	PROPN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	JAK3	_	PROPN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	but	_	CCONJ	_	_	_	_	_	_
44	also	_	ADV	_	_	_	_	_	_
45	IL	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	4	_	NUM	_	NumType=Card	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	activation	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
53	and	_	CCONJ	_	_	_	_	_	_
54	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
55	cell	_	NOUN	_	Number=Sing	_	_	_	_
56	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	negative	_	ADJ	_	Degree=Pos	_	_	_	_
5	version	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	STAT5b	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	STAT5a	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	interfered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	4	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	Ba	_	PROPN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	F3	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	involvement	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	STAT5b	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	control	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
40	through	_	ADP	_	_	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	4R	_	NOUN	_	NumType=Card	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Reporter	_	NOUN	_	Number=Sing	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	finally	_	ADV	_	_	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	promoters	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	STAT5	_	NOUN	_	Degree=Pos	_	_	_	_
12	target	_	NOUN	_	Number=Sing	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	specifically	_	ADV	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	challenging	_	ADJ	_	VerbForm=Ger	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	both	_	DET	_	_	_	_	_	_
29	STAT5a	_	PROPN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	STAT5b	_	PROPN	_	Number=Sing	_	_	_	_
32	can	_	AUX	_	VerbForm=Fin	_	_	_	_
33	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	4	_	NUM	_	NumType=Card	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
41	control	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003539	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	Tax	_	NOUN	_	Number=Sing	_	_	_	_
5	induces	_	VERB	_	Number=Plur	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	various	_	ADJ	_	Degree=Pos	_	_	_	_
9	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
10	early	_	ADJ	_	Degree=Pos	_	_	_	_
11	serum	_	NOUN	_	Number=Sing	_	_	_	_
12	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	etiological	_	ADJ	_	Degree=Pos	_	_	_	_
15	agent	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	adult	_	NOUN	_	Number=Sing	_	_	_	_
18	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
19	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	ATL	_	PROPN	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	mobility	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	shift	_	NOUN	_	Number=Sing	_	_	_	_
8	assay	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
11	lines	_	NOUN	_	Number=Plur	_	_	_	_
12	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	virus	_	NOUN	_	Number=Sing	_	_	_	_
16	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	high	_	ADJ	_	Degree=Pos	_	_	_	_
18	levels	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	activities	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	result	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
14	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	AP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	c	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	Fos	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	Fra-1	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	c-Jun	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	JunB	_	PROPN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	JunD	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Previously	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	c	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	fos	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	transactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	viral	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	Tax1	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
6	line	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	JPX	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	9	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	which	_	DET	_	PronType=Int	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	Tax1	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
23	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	Fra-1	_	PROPN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	c-Jun	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	JunD	_	PROPN	_	Number=Sing	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	also	_	ADV	_	_	_	_	_	_
37	transactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	Tax1	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Tax1	_	NOUN	_	Number=Sing	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	other	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	having	_	VERB	_	VerbForm=Ger	_	_	_	_
12	zinc	_	NOUN	_	Number=Sing	_	_	_	_
13	finger	_	NOUN	_	Number=Sing	_	_	_	_
14	motifs	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	Egr	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	Egr	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	same	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Tax1	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	here	_	ADV	_	PronType=Dem	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	encoded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	members	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
16	early	_	ADJ	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	under	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	control	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	growth	_	NOUN	_	Number=Sing	_	_	_	_
23	signals	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Tax1	_	PROPN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	replace	_	VERB	_	VerbForm=Inf	_	_	_	_
8	growth	_	NOUN	_	Number=Sing	_	_	_	_
9	signals	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	at	_	ADV	_	_	_	_	_	_
12	least	_	ADV	_	Degree=Sup	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	part	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
18	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003541	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Monoallelic	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Pax5	_	NOUN	_	Number=Sing	_	_	_	_
5	:	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	paradigm	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	haploinsufficiency	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
13	Pax	_	NOUN	_	Number=Sing	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	?	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	generally	_	ADV	_	_	_	_	_	_
4	assumed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	most	_	ADJ	_	Degree=Sup	_	_	_	_
7	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	alleles	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Hence	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	diploid	_	ADJ	_	Degree=Pos	_	_	_	_
5	state	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	genome	_	NOUN	_	Number=Sing	_	_	_	_
9	offers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	advantage	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	loss	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	function	_	NOUN	_	Number=Sing	_	_	_	_
19	mutation	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	one	_	NUM	_	NumType=Card	_	_	_	_
22	allele	_	NOUN	_	Number=Sing	_	_	_	_
23	can	_	AUX	_	VerbForm=Fin	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	compensated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	remaining	_	ADJ	_	Degree=Pos	_	_	_	_
30	wild	_	ADJ	_	Degree=Pos	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	type	_	NOUN	_	Number=Sing	_	_	_	_
33	allele	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	same	_	ADJ	_	Degree=Pos	_	_	_	_
37	gene	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Indeed	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	vast	_	ADJ	_	Degree=Pos	_	_	_	_
5	majority	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	disease	_	NOUN	_	Number=Sing	_	_	_	_
9	syndromes	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	engineered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	mutations	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	mouse	_	NOUN	_	Number=Sing	_	_	_	_
16	genome	_	NOUN	_	Number=Sing	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	recessive	_	ADJ	_	Degree=Pos	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	recessiveness	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	'	_	PUNCT	_	_	_	_	_	_
26	default	_	NOUN	_	Number=Sing	_	_	_	_
27	'	_	PUNCT	_	_	_	_	_	_
28	state	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	minority	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	semi	_	ADV	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	as	_	SCONJ	_	_	_	_	_	_
13	heterozygous	_	ADJ	_	Degree=Pos	_	_	_	_
14	loss	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	function	_	NOUN	_	Number=Sing	_	_	_	_
19	mutation	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
26	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	condition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	haploinsufficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	five	_	NUM	_	NumType=Card	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	nine	_	NUM	_	NumType=Card	_	_	_	_
16	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
17	Pax	_	NOUN	_	Number=Sing	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	mouse	_	NOUN	_	Number=Sing	_	_	_	_
25	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
26	mutants	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	disease	_	NOUN	_	Number=Sing	_	_	_	_
30	syndromes	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Pax5	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	subject	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	allele	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	during	_	ADP	_	_	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	development	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Pax5	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	predominantly	_	ADV	_	_	_	_	_	_
4	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	only	_	ADV	_	_	_	_	_	_
7	one	_	NUM	_	NumType=Card	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	alleles	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	early	_	ADJ	_	Degree=Pos	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	lymphoid	_	NOUN	_	Degree=Pos	_	_	_	_
17	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	mature	_	ADJ	_	Degree=Pos	_	_	_	_
20	B	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	while	_	SCONJ	_	_	_	_	_	_
24	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
25	transiently	_	ADV	_	_	_	_	_	_
26	switches	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	biallelic	_	ADJ	_	Degree=Pos	_	_	_	_
30	mode	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	pre-B	_	ADJ	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	immature	_	ADJ	_	Degree=Pos	_	_	_	_
37	B	_	ADJ	_	Degree=Pos	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	consequence	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
8	tissues	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	mosaic	_	NOUN	_	Degree=Pos	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	regard	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	transcribed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	allele	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	heterozygous	_	ADJ	_	Degree=Pos	_	_	_	_
20	mutation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	Pax5	_	NOUN	_	Number=Sing	_	_	_	_
23	therefore	_	ADV	_	_	_	_	_	_
24	results	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	deletion	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	B	_	NOUN	_	Degree=Pos	_	_	_	_
29	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
31	only	_	ADV	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	mutant	_	NOUN	_	Number=Sing	_	_	_	_
34	allele	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	allele	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Pax5	_	NOUN	_	Number=Sing	_	_	_	_
8	raises	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	intriguing	_	VERB	_	Degree=Pos	_	_	_	_
11	possibility	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	monoallelic	_	ADJ	_	Degree=Pos	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	also	_	ADV	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
20	causing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	haploinsufficiency	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	other	_	ADJ	_	Degree=Pos	_	_	_	_
25	Pax	_	NOUN	_	Number=Sing	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	review	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	discuss	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	different	_	ADJ	_	Degree=Pos	_	_	_	_
8	models	_	NOUN	_	Number=Plur	_	_	_	_
9	accounting	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	haploinsufficiency	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
15	Pax	_	NOUN	_	Number=Sing	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	further	_	ADJ	_	Degree=Pos	_	_	_	_
20	evidence	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	support	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	allele	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	regulation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	Pax5	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	discuss	_	VERB	_	VerbForm=Inf	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	implication	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
37	findings	_	NOUN	_	Number=Plur	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	context	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	recent	_	ADJ	_	Degree=Pos	_	_	_	_
44	literature	_	NOUN	_	Number=Sing	_	_	_	_
45	describing	_	VERB	_	VerbForm=Ger	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	stochastic	_	ADJ	_	Degree=Pos	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	monoallelic	_	ADJ	_	Degree=Pos	_	_	_	_
50	activation	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	other	_	ADJ	_	Degree=Pos	_	_	_	_
53	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
54	genes	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003546	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	[	_	PUNCT	_	_	_	_	_	_
2	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	24,25	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_

1	D3	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	dioxyvit	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	Ca	_	PROPN	_	Number=Sing	_	_	_	_
7	metabolism	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	immune	_	VERB	_	Degree=Pos	_	_	_	_
10	status	_	NOUN	_	Number=Sing	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
13	kidney	_	NOUN	_	Number=Sing	_	_	_	_
14	failure	_	NOUN	_	Number=Sing	_	_	_	_
15	]	_	PUNCT	_	_	_	_	_	_

1	Active	_	ADJ	_	Degree=Pos	_	_	_	_
2	metabolite	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
5	D3	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	24R,25	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	OH	_	INTJ	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	2D3	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	dioxyvit	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	daily	_	ADJ	_	Degree=Pos	_	_	_	_
20	dose	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	100	_	NUM	_	NumType=Card	_	_	_	_
23	micrograms	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	treatment	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	children	_	NOUN	_	Number=Plur	_	_	_	_
28	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	tubulointerstitial	_	ADJ	_	Degree=Pos	_	_	_	_
31	disease	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	kidney	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
37	glomerulonephritis	_	NOUN	_	Number=Sing	_	_	_	_
38	under	_	ADP	_	_	_	_	_	_
39	conditions	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	kidney	_	NOUN	_	Number=Sing	_	_	_	_
42	insufficiency	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	drug	_	NOUN	_	Number=Sing	_	_	_	_
3	exhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
5	normalizing	_	ADJ	_	VerbForm=Ger	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	patterns	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	calcium	_	NOUN	_	Number=Sing	_	_	_	_
11	metabolism	_	NOUN	_	Number=Sing	_	_	_	_
12	:	_	PUNCT	_	_	_	_	_	_
13	increase	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	total	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	ionized	_	VERB	_	Degree=Pos	_	_	_	_
18	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	25	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	OHD	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	decrease	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	concentration	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	parath	_	NOUN	_	Number=Sing	_	_	_	_
31	hormone	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	osteocalcine	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	blood	_	NOUN	_	Number=Sing	_	_	_	_
36	serum	_	NOUN	_	Number=Sing	_	_	_	_
37	as	_	ADV	_	_	_	_	_	_
38	well	_	ADV	_	Degree=Pos	_	_	_	_
39	as	_	ADP	_	_	_	_	_	_
40	on	_	ADP	_	_	_	_	_	_
41	immunological	_	ADJ	_	Degree=Pos	_	_	_	_
42	parameters	_	NOUN	_	Number=Plur	_	_	_	_
43	:	_	PUNCT	_	_	_	_	_	_
44	restoration	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	content	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	T	_	NOUN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	0-lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Concentration	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	receptors	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	hormonal	_	ADJ	_	Degree=Pos	_	_	_	_
6	form	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	1,25	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	OH	_	INTJ	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	2D3	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	under	_	ADP	_	_	_	_	_	_
21	conditions	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
24	kidney	_	NOUN	_	Number=Sing	_	_	_	_
25	insufficiency	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	while	_	SCONJ	_	_	_	_	_	_
28	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	after	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	dioxyvit	_	NOUN	_	Number=Sing	_	_	_	_
34	action	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
37	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	only	_	ADV	_	_	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	patients	_	NOUN	_	Number=Sing	_	_	_	_
41	with	_	ADP	_	_	_	_	_	_
42	glomerulonephritis	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Specific	_	ADJ	_	Degree=Pos	_	_	_	_
2	calcitropic	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	dioxyvit	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	simultaneous	_	ADJ	_	Degree=Pos	_	_	_	_
8	correction	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
11	D	_	PROPN	_	Number=Sing	_	_	_	_
12	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	apparently	_	ADV	_	_	_	_	_	_
15	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	high	_	ADJ	_	Degree=Pos	_	_	_	_
18	efficacy	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	drug	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	treatment	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	calcium	_	NOUN	_	Number=Sing	_	_	_	_
26	metabolism	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	immunity	_	NOUN	_	Number=Sing	_	_	_	_
29	impairments	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	children	_	NOUN	_	Number=Plur	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	renal	_	ADJ	_	Degree=Pos	_	_	_	_
34	deteriorations	_	NOUN	_	Number=Plur	_	_	_	_
35	at	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	step	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
40	kidney	_	NOUN	_	Number=Sing	_	_	_	_
41	insufficiency	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003547	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Detection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
4	phosphorylated	_	VERB	_	Number=Sing	_	_	_	_
5	STAT	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	flow	_	NOUN	_	Number=Sing	_	_	_	_
10	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	applied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	flow	_	NOUN	_	Number=Sing	_	_	_	_
5	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	investigation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	interferon	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	gamma	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	approach	_	NOUN	_	Number=Sing	_	_	_	_
3	uses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
5	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	distinguish	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	between	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	native	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	forms	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	STAT	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	enables	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	quantitative	_	ADJ	_	Degree=Pos	_	_	_	_
6	assessment	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	STAT	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	discrete	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	basis	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	both	_	ADV	_	_	_	_	_	_
20	more	_	ADV	_	_	_	_	_	_
21	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	less	_	ADJ	_	Degree=Cmp	_	_	_	_
24	time	_	NOUN	_	Number=Sing	_	_	_	_
25	consuming	_	VERB	_	VerbForm=Ger	_	_	_	_
26	than	_	ADP	_	_	_	_	_	_
27	immunoblotting	_	ADJ	_	Degree=Pos	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	allows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	discrimination	_	NOUN	_	Number=Sing	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	mixture	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	response	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	interferon	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	gamma	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	approach	_	NOUN	_	Number=Sing	_	_	_	_
3	should	_	AUX	_	VerbForm=Fin	_	_	_	_
4	allow	_	VERB	_	VerbForm=Inf	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	evaluation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	different	_	ADJ	_	Degree=Pos	_	_	_	_
10	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	signaling	_	NOUN	_	Number=Sing	_	_	_	_
12	pathways	_	NOUN	_	Number=Plur	_	_	_	_
13	using	_	VERB	_	VerbForm=Ger	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	combination	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
18	reagents	_	NOUN	_	Number=Plur	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	specific	_	ADJ	_	Degree=Pos	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	native	_	ADJ	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	proteins	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Application	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	form	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	testing	_	NOUN	_	Number=Sing	_	_	_	_
7	should	_	AUX	_	VerbForm=Fin	_	_	_	_
8	prove	_	VERB	_	VerbForm=Inf	_	_	_	_
9	valuable	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	screening	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
14	defects	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	patients	_	NOUN	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	recurrent	_	ADJ	_	Degree=Pos	_	_	_	_
20	infections	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	technique	_	NOUN	_	Number=Sing	_	_	_	_
6	should	_	AUX	_	VerbForm=Fin	_	_	_	_
7	permit	_	VERB	_	VerbForm=Inf	_	_	_	_
8	dissection	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	full	_	ADJ	_	Degree=Pos	_	_	_	_
12	range	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	signaling	_	NOUN	_	Number=Sing	_	_	_	_
16	pathways	_	NOUN	_	Number=Plur	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003552	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
3	binding	_	VERB	_	Number=Sing	_	_	_	_
4	sites	_	NOUN	_	Number=Plur	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	have	_	VERB	_	VerbForm=Inf	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
8	effect	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	via	_	ADP	_	_	_	_	_	_
13	interactions	_	NOUN	_	Number=Plur	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	GR	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Cortisol	_	ADJ	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	various	_	ADJ	_	Degree=Pos	_	_	_	_
4	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
5	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
6	bind	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	GR	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	one	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Cortivazol	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	CVZ	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	unique	_	ADJ	_	Degree=Pos	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	high	_	ADJ	_	Degree=Pos	_	_	_	_
10	potency	_	NOUN	_	Number=Sing	_	_	_	_
11	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
12	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	phenylpyrazol	_	NOUN	_	Number=Sing	_	_	_	_
18	fused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	A	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	ring	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
27	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	displays	_	VERB	_	Number=Plur	_	_	_	_
30	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
31	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	two	_	NUM	_	NumType=Card	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	more	_	ADJ	_	Degree=Cmp	_	_	_	_
36	sites	_	NOUN	_	Number=Plur	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
40	from	_	ADP	_	_	_	_	_	_
41	CEM	_	PROPN	_	Number=Sing	_	_	_	_
42	C7	_	PROPN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
46	human	_	ADJ	_	Degree=Pos	_	_	_	_
47	acute	_	NOUN	_	Number=Sing	_	_	_	_
48	lymphoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
49	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
50	line	_	NOUN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
9	affinity	_	NOUN	_	Number=Sing	_	_	_	_
10	class	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	similar	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	affinity	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	molarity	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
22	recognized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
3	affinity	_	NOUN	_	Number=Sing	_	_	_	_
4	sites	_	NOUN	_	Number=Plur	_	_	_	_
5	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	CVZ	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	20	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	50	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
14	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
15	affinity	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	CVZ	_	PROPN	_	Number=Sing	_	_	_	_
20	's	_	PART	_	_	_	_	_	_
21	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	biological	_	ADJ	_	Degree=Pos	_	_	_	_
23	effects	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
3	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	resistant	_	VERB	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	effects	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	CVZ	_	PROPN	_	Number=Sing	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	lyses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	single	_	ADJ	_	Degree=Pos	_	_	_	_
22	class	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	sites	_	NOUN	_	Number=Plur	_	_	_	_
25	similar	_	ADJ	_	Degree=Pos	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	high	_	ADJ	_	Degree=Pos	_	_	_	_
29	affinity	_	NOUN	_	Number=Sing	_	_	_	_
30	site	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	CEM	_	PROPN	_	Number=Sing	_	_	_	_
33	C7	_	PROPN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	carried	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	out	_	ADP	_	_	_	_	_	_
5	experiments	_	NOUN	_	Number=Plur	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	define	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nature	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
13	affinity	_	NOUN	_	Number=Sing	_	_	_	_
14	CVZ	_	PROPN	_	Number=Sing	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
5	:	_	PUNCT	_	_	_	_	_	_

1	1	_	X	_	_	_	_	_	_
2	)	_	PUNCT	_	_	_	_	_	_
3	CVZ	_	PROPN	_	Number=Sing	_	_	_	_
4	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	more	_	ADJ	_	Degree=Cmp	_	_	_	_
6	than	_	ADP	_	_	_	_	_	_
7	one	_	NUM	_	NumType=Card	_	_	_	_
8	binding	_	NOUN	_	Degree=Pos	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	independent	_	ADJ	_	Degree=Pos	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	line	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	IM	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	9	_	NUM	_	NumType=Card	_	_	_	_
24	;	_	PUNCT	_	_	_	_	_	_
25	2	_	X	_	_	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	antiglucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
29	RU	_	PROPN	_	Number=Sing	_	_	_	_
30	38486	_	NUM	_	Number=Sing	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	able	_	ADJ	_	Degree=Pos	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	block	_	VERB	_	VerbForm=Inf	_	_	_	_
35	both	_	CCONJ	_	_	_	_	_	_
36	CVZ	_	PROPN	_	Number=Sing	_	_	_	_
37	's	_	PART	_	_	_	_	_	_
38	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
41	affinity	_	NOUN	_	Number=Sing	_	_	_	_
42	sites	_	NOUN	_	Number=Plur	_	_	_	_
43	;	_	PUNCT	_	_	_	_	_	_
44	3	_	X	_	_	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	all	_	DET	_	_	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	CVZ	_	PROPN	_	Number=Sing	_	_	_	_
49	's	_	PART	_	_	_	_	_	_
50	binding	_	NOUN	_	Number=Sing	_	_	_	_
51	sites	_	NOUN	_	Number=Plur	_	_	_	_
52	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
53	on	_	ADP	_	_	_	_	_	_
54	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
55	protein	_	NOUN	_	Number=Sing	_	_	_	_
56	immunologically	_	ADV	_	_	_	_	_	_
57	indistinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
58	from	_	ADP	_	_	_	_	_	_
59	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
60	human	_	ADJ	_	Degree=Pos	_	_	_	_
61	GR	_	NOUN	_	Number=Sing	_	_	_	_
62	;	_	PUNCT	_	_	_	_	_	_
63	and	_	CCONJ	_	_	_	_	_	_
64	4	_	X	_	_	_	_	_	_
65	)	_	PUNCT	_	_	_	_	_	_
66	freshly	_	ADV	_	_	_	_	_	_
67	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
68	clones	_	NOUN	_	Number=Plur	_	_	_	_
69	of	_	ADP	_	_	_	_	_	_
70	CVZ	_	PROPN	_	Number=Sing	_	_	_	_
71	-	_	PUNCT	_	_	_	_	_	_
72	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
73	cells	_	NOUN	_	Number=Plur	_	_	_	_
74	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
75	lost	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
76	all	_	DET	_	_	_	_	_	_
77	binding	_	NOUN	_	Number=Sing	_	_	_	_
78	sites	_	NOUN	_	Number=Plur	_	_	_	_
79	for	_	ADP	_	_	_	_	_	_
80	CVZ	_	PROPN	_	Number=Sing	_	_	_	_
81	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CVZ	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	recognizing	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	sites	_	NOUN	_	Number=Plur	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	GR	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	very	_	ADV	_	_	_	_	_	_
20	similar	_	ADJ	_	Degree=Pos	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003553	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
6	colony	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	secretion	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	bioactive	_	ADJ	_	Degree=Pos	_	_	_	_
21	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
22	colony	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappa	_	PROPN	_	Number=Sing	_	_	_	_
39	B.	_	PROPN	_	Number=Sing	_	_	_	_
40	Human	_	ADJ	_	Degree=Pos	_	_	_	_
41	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
42	blood	_	NOUN	_	Number=Sing	_	_	_	_
43	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	Mo	_	NOUN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	constitutively	_	ADV	_	_	_	_	_	_
48	display	_	VERB	_	VerbForm=Inf	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	beta	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	chain	_	NOUN	_	Number=Sing	_	_	_	_
53	of	_	ADP	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	receptor	_	NOUN	_	Number=Sing	_	_	_	_
56	for	_	ADP	_	_	_	_	_	_
57	IL	_	PROPN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	2	_	NUM	_	NumType=Card	_	_	_	_
60	,	_	PUNCT	_	_	_	_	_	_
61	whereas	_	SCONJ	_	_	_	_	_	_
62	expression	_	NOUN	_	Number=Sing	_	_	_	_
63	of	_	ADP	_	_	_	_	_	_
64	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
65	IL	_	PROPN	_	Number=Sing	_	_	_	_
66	-	_	PUNCT	_	_	_	_	_	_
67	2R	_	PROPN	_	Number=Sing	_	_	_	_
68	alpha	_	NOUN	_	Number=Sing	_	_	_	_
69	-	_	PUNCT	_	_	_	_	_	_
70	chain	_	NOUN	_	Number=Sing	_	_	_	_
71	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
72	not	_	PART	_	_	_	_	_	_
73	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
74	but	_	CCONJ	_	_	_	_	_	_
75	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
76	with	_	ADP	_	_	_	_	_	_
77	IL	_	PROPN	_	Number=Sing	_	_	_	_
78	-	_	PUNCT	_	_	_	_	_	_
79	2	_	NUM	_	NumType=Card	_	_	_	_
80	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	DET	_	_	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	IL	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	binding	_	NOUN	_	Degree=Pos	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	leads	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
22	CSF	_	PROPN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	M	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	CSF	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	Mo	_	NOUN	_	Number=Sing	_	_	_	_
31	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	M	_	NUM	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	CSF	_	PROPN	_	Number=Sing	_	_	_	_
38	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
41	release	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	bioactive	_	ADJ	_	Degree=Pos	_	_	_	_
44	M	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	CSF	_	NOUN	_	Number=Sing	_	_	_	_
47	protein	_	NOUN	_	Number=Sing	_	_	_	_
48	as	_	SCONJ	_	_	_	_	_	_
49	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	by	_	ADP	_	_	_	_	_	_
51	ELISA	_	PROPN	_	Number=Sing	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	IL	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	2	_	NUM	_	NumType=Card	_	_	_	_
58	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
59	release	_	NOUN	_	Number=Sing	_	_	_	_
60	of	_	ADP	_	_	_	_	_	_
61	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
62	activity	_	NOUN	_	Number=Sing	_	_	_	_
63	-	_	PUNCT	_	_	_	_	_	_
64	stimulating	_	VERB	_	VerbForm=Ger	_	_	_	_
65	growth	_	NOUN	_	Number=Sing	_	_	_	_
66	of	_	ADP	_	_	_	_	_	_
67	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
68	-	_	PUNCT	_	_	_	_	_	_
69	type	_	NOUN	_	Number=Sing	_	_	_	_
70	colonies	_	NOUN	_	Number=Plur	_	_	_	_
71	by	_	ADP	_	_	_	_	_	_
72	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
73	neutralizing	_	NOUN	_	VerbForm=Ger	_	_	_	_
74	anti-M	_	NOUN	_	Number=Sing	_	_	_	_
75	-	_	PUNCT	_	_	_	_	_	_
76	CSF	_	NOUN	_	Number=Sing	_	_	_	_
77	antibody	_	NOUN	_	Number=Sing	_	_	_	_
78	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	M	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	CSF	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	preceded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
29	recognition	_	NOUN	_	Number=Sing	_	_	_	_
30	sequence	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	5	_	NUM	_	NumType=Card	_	_	_	_
34	'	_	PUNCT	_	_	_	_	_	_
35	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
36	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
37	region	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	M	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	CSF	_	NOUN	_	Number=Sing	_	_	_	_
43	gene	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	using	_	VERB	_	VerbForm=Ger	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	herpes	_	NOUN	_	Number=Sing	_	_	_	_
9	thymidine	_	VERB	_	Number=Sing	_	_	_	_
10	kinase	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	construct	_	VERB	_	Number=Sing	_	_	_	_
13	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	consensus	_	NOUN	_	Number=Sing	_	_	_	_
20	sequence	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	PROPN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	binding	_	VERB	_	Number=Sing	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
42	protein	_	NOUN	_	Number=Sing	_	_	_	_
43	confers	_	VERB	_	Number=Plur	_	_	_	_
44	reporter	_	NOUN	_	Number=Sing	_	_	_	_
45	gene	_	NOUN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	human	_	ADJ	_	Degree=Pos	_	_	_	_
48	growth	_	NOUN	_	Number=Sing	_	_	_	_
49	hormone	_	NOUN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	activity	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	findings	_	NOUN	_	Number=Plur	_	_	_	_
6	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	M	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	CSF	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	blood	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	Mo	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
26	evidence	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	involvement	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
36	regulation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003557	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	Tax	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	STAT5	_	ADJ	_	Degree=Pos	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	Tax	_	NOUN	_	Number=Sing	_	_	_	_
13	transforms	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	normal	_	ADJ	_	Degree=Pos	_	_	_	_
15	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	presence	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	vitro	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	STAT	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	family	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	pivotal	_	ADJ	_	Degree=Pos	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	functions	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	various	_	ADJ	_	Degree=Pos	_	_	_	_
21	type	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	involvement	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	STATs	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transformation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_
17	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1-transformed	_	NUM	_	Number=Sing	_	_	_	_

1	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
2	lines	_	NOUN	_	Number=Plur	_	_	_	_
3	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
5	amounts	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
12	RNA	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	proteins	_	VERB	_	Number=Plur	_	_	_	_
15	than	_	ADP	_	_	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	negative	_	ADJ	_	Degree=Pos	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	Tax	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	line	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	then	_	ADV	_	PronType=Dem	_	_	_	_
24	stimulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	neither	_	CCONJ	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	line	_	NOUN	_	Number=Sing	_	_	_	_
13	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
14	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
9	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	normal	_	ADJ	_	Degree=Pos	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
23	blood	_	NOUN	_	Number=Sing	_	_	_	_
24	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	Tax	_	NOUN	_	Number=Sing	_	_	_	_
13	enhances	_	NOUN	_	Number=Plur	_	_	_	_
14	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	functions	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	virus	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	hence	_	ADV	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	induction	_	NOUN	_	Number=Sing	_	_	_	_
27	may	_	AUX	_	VerbForm=Fin	_	_	_	_
28	play	_	VERB	_	VerbForm=Inf	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	role	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
37	transformation	_	NOUN	_	Number=Sing	_	_	_	_
38	steps	_	NOUN	_	Number=Plur	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	T	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_
48	Document	_	NOUN	_	Number=Sing	_	_	_	_
49	003003559	_	NUM	_	NumType=Card	_	_	_	_
50	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	microtitre	_	NOUN	_	Number=Sing	_	_	_	_
3	assay	_	NOUN	_	Number=Sing	_	_	_	_
4	system	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
7	receptors	_	NOUN	_	Number=Plur	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	concentration	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	myocardial	_	ADJ	_	Degree=Pos	_	_	_	_
14	infarction	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	major	_	ADJ	_	Degree=Pos	_	_	_	_
3	difficulty	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	determination	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	sites	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	very	_	ADV	_	_	_	_	_	_
13	complicated	_	ADJ	_	Degree=Pos	_	_	_	_
14	assay	_	NOUN	_	Number=Sing	_	_	_	_
15	procedure	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	microtitre	_	NOUN	_	Number=Sing	_	_	_	_
7	assay	_	NOUN	_	Number=Sing	_	_	_	_
8	system	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
11	receptors	_	NOUN	_	Number=Plur	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	whole	_	ADJ	_	Degree=Pos	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	competitive	_	ADJ	_	Degree=Pos	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	radioassay	_	NOUN	_	Number=Sing	_	_	_	_
21	using	_	VERB	_	VerbForm=Ger	_	_	_	_
22	[	_	PUNCT	_	_	_	_	_	_
23	3H	_	NOUN	_	Number=Sing	_	_	_	_
24	]	_	PUNCT	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	radioligand	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	modification	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	previously	_	ADV	_	_	_	_	_	_
6	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	protocol	_	NOUN	_	Number=Sing	_	_	_	_
8	simplifies	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	reduces	_	VERB	_	Number=Plur	_	_	_	_
11	laboratory	_	ADJ	_	Number=Sing	_	_	_	_
12	work	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	allows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	assay	_	NOUN	_	Degree=Pos	_	_	_	_
16	reproducibility	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	more	_	ADV	_	_	_	_	_	_
21	reliably	_	ADV	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	enabled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	perform	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	test	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
9	blood	_	NOUN	_	Number=Sing	_	_	_	_
10	samples	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	parallel	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	cardiac	_	ADJ	_	Degree=Pos	_	_	_	_
17	infarction	_	NOUN	_	Number=Sing	_	_	_	_
18	patients	_	NOUN	_	Number=Plur	_	_	_	_
19	over	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	12	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	day	_	NOUN	_	Number=Sing	_	_	_	_
24	period	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	test	_	NOUN	_	VerbForm=Inf	_	_	_	_
27	if	_	SCONJ	_	_	_	_	_	_
28	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
35	'	_	PUNCT	_	_	_	_	_	_
36	stressful	_	ADJ	_	Degree=Pos	_	_	_	_
37	'	_	PUNCT	_	_	_	_	_	_
38	disease	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
4	day	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	disease	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	capacity	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	significantly	_	ADV	_	_	_	_	_	_
14	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	without	_	ADP	_	_	_	_	_	_
16	alteration	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	ligand	_	NOUN	_	Number=Sing	_	_	_	_
22	affinity	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	whereas	_	SCONJ	_	_	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	days	_	NOUN	_	Number=Plur	_	_	_	_
27	4	_	NUM	_	NumType=Card	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	12	_	NUM	_	NumType=Card	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	number	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	receptor	_	NOUN	_	Number=Sing	_	_	_	_
34	sites	_	NOUN	_	Number=Plur	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	normal	_	ADJ	_	Degree=Pos	_	_	_	_
37	again	_	ADV	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	result	_	NOUN	_	Number=Sing	_	_	_	_
3	fits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	well	_	ADV	_	Degree=Pos	_	_	_	_
5	into	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	general	_	ADJ	_	Degree=Pos	_	_	_	_
8	observation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	stress	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	down	_	ADP	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	immune	_	ADJ	_	Degree=Pos	_	_	_	_
18	responses	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003563	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	suppression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	function	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	serine	_	NOUN	_	Number=Sing	_	_	_	_
16	protease	_	NOUN	_	Number=Sing	_	_	_	_
17	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	N	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	acetylcysteine	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Direct	_	ADJ	_	Degree=Pos	_	_	_	_
2	evidence	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	N-acetylcysteine	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	NAC	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	immune	_	ADJ	_	Degree=Pos	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
14	blood	_	NOUN	_	Number=Sing	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	level	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	kappa	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	B	_	PROPN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	presented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	NAC	_	PROPN	_	Number=Sing	_	_	_	_
5	blocks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	suppression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	mitogenesis	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	protease	_	NOUN	_	Number=Sing	_	_	_	_
17	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
18	such	_	ADJ	_	Degree=Pos	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	N	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	tosylphenylalanine	_	NOUN	_	Number=Sing	_	_	_	_
23	chloromethyl	_	NOUN	_	Number=Sing	_	_	_	_
24	ketone	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	TPCK	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
3	responses	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	CD4	_	NOUN	_	Number=Sing	_	_	_	_
7	+	_	SYM	_	_	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	CD8	_	PROPN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	more	_	ADV	_	_	_	_	_	_
6	strongly	_	ADV	_	_	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	TPCK	_	PROPN	_	Number=Sing	_	_	_	_
9	when	_	ADV	_	PronType=Int	_	_	_	_
10	anti-CD28	_	PROPN	_	Degree=Pos	_	_	_	_
11	rather	_	ADV	_	_	_	_	_	_
12	than	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
15	ester	_	PROPN	_	Number=Sing	_	_	_	_
16	PMA	_	PROPN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	mitogenic	_	ADJ	_	Number=Sing	_	_	_	_
22	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Cytokine	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	6	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	INF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	production	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	95	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	SYM	_	_	_	_	_	_
20	100	_	NUM	_	NumType=Card	_	_	_	_
21	%	_	SYM	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	TPCK	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	totally	_	ADV	_	_	_	_	_	_
28	suppress	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	mitogenesis	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	CD4	_	PROPN	_	Number=Sing	_	_	_	_
33	+	_	SYM	_	_	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	CD8	_	NOUN	_	Number=Sing	_	_	_	_
36	+	_	SYM	_	_	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	TPCK	_	NOUN	_	Number=Sing	_	_	_	_
11	virtually	_	ADV	_	_	_	_	_	_
12	abolishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	less	_	ADJ	_	Degree=Cmp	_	_	_	_
16	than	_	ADP	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	%	_	SYM	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	levels	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	B	_	PROPN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	not	_	ADV	_	_	_	_	_	_
31	Oct	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	whole	_	ADJ	_	Degree=Pos	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	extracts	_	NOUN	_	Number=Plur	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	T	_	NOUN	_	Number=Sing	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Strikingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	TPCK	_	NOUN	_	Number=Sing	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	when	_	ADV	_	PronType=Int	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	pretreated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	15	_	NUM	_	NumType=Card	_	_	_	_
17	min	_	NOUN	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	5	_	NUM	_	NumType=Card	_	_	_	_
20	mM	_	NOUN	_	NumType=Card	_	_	_	_
21	NAC	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	NAC	_	PROPN	_	Number=Sing	_	_	_	_
2	not	_	ADV	_	_	_	_	_	_
3	only	_	ADV	_	_	_	_	_	_
4	blocks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	TPCK	_	NOUN	_	Number=Sing	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	mitogenesis	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	>	_	SYM	_	_	_	_	_	_
17	2.5	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	fold	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	some	_	DET	_	_	_	_	_	_
22	cases	_	NOUN	_	Number=Plur	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	upon	_	ADP	_	_	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	unsuppressed	_	ADJ	_	Degree=Pos	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	notion	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	proteases	_	NOUN	_	Number=Plur	_	_	_	_
19	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	obligate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	roles	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	T	_	PROPN	_	Number=Sing	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	mitogenesis	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	roles	_	NOUN	_	Number=Plur	_	_	_	_
30	that	_	PRON	_	PronType=Rel	_	_	_	_
31	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	significantly	_	ADV	_	_	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	NAC	_	PROPN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003571	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Detection	_	NOUN	_	Number=Sing	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	non-erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	EF1	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	EF1	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	critical	_	ADJ	_	Degree=Pos	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	presence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	mobility	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	sequence	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	binding	_	VERB	_	Number=Sing	_	_	_	_
19	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	EF1	_	NOUN	_	Number=Sing	_	_	_	_
22	at	_	ADP	_	_	_	_	_	_
23	low	_	ADJ	_	Degree=Pos	_	_	_	_
24	abundance	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	wide	_	ADJ	_	Degree=Pos	_	_	_	_
28	variety	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	non-erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	types	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
5	report	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	EF1	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	like	_	ADJ	_	Degree=Pos	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	non-erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	play	_	VERB	_	VerbForm=Inf	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	role	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	regulation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	genes	_	NOUN	_	Number=Plur	_	_	_	_
29	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	such	_	ADJ	_	Degree=Pos	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003578	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	newly	_	ADV	_	_	_	_	_	_
3	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	megakaryoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	line	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	differentiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	red	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	presence	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	produces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	platelet	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	like	_	ADP	_	Degree=Pos	_	_	_	_
24	particles	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	August	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	1992	_	NUM	_	NumType=Card	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	established	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	NS	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	Meg	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	patient	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	megakaryoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
22	transformation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	Philadelphia	_	PROPN	_	Number=Sing	_	_	_	_
25	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	positive	_	ADJ	_	Degree=Pos	_	_	_	_
28	chronic	_	ADJ	_	Number=Sing	_	_	_	_
29	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
30	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NS	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Meg	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	positive	_	ADJ	_	Degree=Pos	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	naphthyl	_	ADJ	_	Degree=Pos	_	_	_	_
12	acetate	_	NOUN	_	Number=Sing	_	_	_	_
13	esterase	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	periodic	_	ADJ	_	Degree=Pos	_	_	_	_
16	acid	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	Schiff	_	PROPN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	PAS	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	staining	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	surface	_	NOUN	_	Number=Sing	_	_	_	_
26	CD4	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	CD7	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	CD13	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	CD34	_	PROPN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	CD41a	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	glycophorin	_	NOUN	_	Number=Sing	_	_	_	_
38	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	antigens	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Ultrastructurally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	granules	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	demarcation	_	NOUN	_	Number=Sing	_	_	_	_
11	membranes	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	platelet	_	NOUN	_	Number=Sing	_	_	_	_
15	peroxidase	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NS	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Meg	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	spontaneously	_	ADV	_	_	_	_	_	_
7	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	platelet	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	like	_	ADP	_	Degree=Pos	_	_	_	_
11	particles	_	NOUN	_	Number=Plur	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	granules	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	mitochondria	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	dense	_	ADJ	_	Degree=Pos	_	_	_	_
21	bodies	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	strongly	_	ADV	_	_	_	_	_	_
24	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	platelet	_	NOUN	_	Number=Sing	_	_	_	_
26	production	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Erythropoietin	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	Epo	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
9	colony	_	NOUN	_	Number=Sing	_	_	_	_
10	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	GM	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	CSF	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	promoted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	growth	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	NS	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	Meg	_	PROPN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Phorbol	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	12-myristate-13-acetate	_	NOUN	_	Number=Sing	_	_	_	_
4	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	CD41a	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	CD61	_	PROPN	_	Number=Sing	_	_	_	_
12	antigens	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Ten	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	day	_	NOUN	_	Number=Sing	_	_	_	_
4	exposure	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	Epo	_	PROPN	_	Number=Sing	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	mature	_	ADJ	_	Degree=Pos	_	_	_	_
9	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	red	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	benzidine	_	NOUN	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	positive	_	ADJ	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	positive	_	ADJ	_	Degree=Pos	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	hemoglobin	_	NOUN	_	Number=Sing	_	_	_	_
10	F	_	PROPN	_	Number=Sing	_	_	_	_
11	staining	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Untreated	_	ADJ	_	Degree=Pos	_	_	_	_
2	NS	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Meg	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	Epo	_	PROPN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	EpoR	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	GATA	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	gamma	_	NOUN	_	Number=Sing	_	_	_	_
30	globin	_	NOUN	_	Degree=Pos	_	_	_	_
31	genes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	NS	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Meg	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	undergo	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	terminal	_	ADJ	_	Number=Sing	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
17	lineages	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	line	_	NOUN	_	Number=Sing	_	_	_	_
4	should	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	very	_	ADV	_	_	_	_	_	_
8	useful	_	ADJ	_	Degree=Pos	_	_	_	_
9	tool	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	investigation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
18	maturation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003583	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cytomegalovirus	_	PROPN	_	Number=Sing	_	_	_	_
2	modulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	6	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Complications	_	NOUN	_	Number=Plur	_	_	_	_
2	after	_	ADP	_	_	_	_	_	_
3	lung	_	NOUN	_	Number=Sing	_	_	_	_
4	transplantation	_	NOUN	_	Number=Sing	_	_	_	_
5	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	development	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	rejection	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	incidence	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	infection	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	particularly	_	ADV	_	_	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	cytomegalovirus	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	CMV	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	recent	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	6	_	NUM	_	NumType=Card	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	detect	_	VERB	_	VerbForm=Inf	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	infection	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	rejection	_	NOUN	_	Number=Sing	_	_	_	_
22	after	_	ADP	_	_	_	_	_	_
23	lung	_	NOUN	_	Number=Sing	_	_	_	_
24	transplantation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	play	_	VERB	_	VerbForm=Inf	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	development	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	bronchiolitis	_	NOUN	_	Number=Sing	_	_	_	_
16	obliterans	_	NOUN	_	Number=Plur	_	_	_	_
17	after	_	ADP	_	_	_	_	_	_
18	transplantation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	CMV	_	PROPN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	development	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	bronchiolitis	_	NOUN	_	Number=Sing	_	_	_	_
11	obliterans	_	NOUN	_	Number=Plur	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	transplantation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	determined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	whether	_	SCONJ	_	_	_	_	_	_
18	CMV	_	PROPN	_	Number=Sing	_	_	_	_
19	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	6	_	NUM	_	NumType=Card	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	CMV	_	PROPN	_	Number=Sing	_	_	_	_
5	infection	_	NOUN	_	Number=Sing	_	_	_	_
6	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	both	_	CCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
16	blood	_	NOUN	_	Number=Sing	_	_	_	_
17	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	CMV	_	PROPN	_	Number=Sing	_	_	_	_
7	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
8	early	_	ADJ	_	Degree=Pos	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	product	_	NOUN	_	Number=Sing	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	6	_	NUM	_	NumType=Card	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	CMV	_	PROPN	_	Number=Sing	_	_	_	_
6	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
7	early	_	ADJ	_	Degree=Pos	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	product	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	upon	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	presence	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
21	sites	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	6	_	NUM	_	NumType=Card	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CMV	_	PROPN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	cofactor	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	development	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	rejection	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	infection	_	NOUN	_	Number=Sing	_	_	_	_
18	after	_	ADP	_	_	_	_	_	_
19	transplantation	_	NOUN	_	Number=Sing	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	effects	_	NOUN	_	Number=Plur	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	6	_	NUM	_	NumType=Card	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_
28	Document	_	NOUN	_	Number=Sing	_	_	_	_
29	003003585	_	NUM	_	NumType=Card	_	_	_	_
30	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Signal	_	ADJ	_	Number=Sing	_	_	_	_
2	transduction	_	NOUN	_	Number=Sing	_	_	_	_
3	pathways	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	normal	_	ADJ	_	Degree=Pos	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	mediators	_	NOUN	_	Number=Plur	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	comparative	_	ADJ	_	Degree=Pos	_	_	_	_
15	study	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	normal	_	ADJ	_	Degree=Pos	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	putative	_	ADJ	_	Degree=Pos	_	_	_	_
26	roles	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	functionality	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	biology	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
4	colony	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	GM	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	CSF	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
22	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	92	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kDa	_	NOUN	_	Number=Sing	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	normal	_	ADJ	_	Degree=Pos	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	92	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kDa	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	ADV	_	_	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	STATs1	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	3	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	6	_	NUM	_	NumType=Card	_	_	_	_
20	nor	_	CCONJ	_	_	_	_	_	_
21	c	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	fes	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	vav	_	NOUN	_	Number=Sing	_	_	_	_
26	protooncogene	_	NOUN	_	Number=Sing	_	_	_	_
27	products	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
32	translocation	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	specific	_	ADJ	_	Degree=Pos	_	_	_	_
40	DNA	_	NOUN	_	Number=Sing	_	_	_	_
41	binding	_	NOUN	_	Number=Sing	_	_	_	_
42	capacity	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	potentiation	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	trancriptional	_	ADJ	_	Degree=Pos	_	_	_	_
48	activity	_	NOUN	_	Number=Sing	_	_	_	_
49	by	_	ADP	_	_	_	_	_	_
50	GM	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	CSF	_	PROPN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	N-formyl-methionyl	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	leucyl	_	ADJ	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	phenylalanine	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	FMLP	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
11	myristate	_	NOUN	_	Number=Sing	_	_	_	_
12	acetate	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	PMA	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
18	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	42	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	44	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kDa	_	NOUN	_	Number=Sing	_	_	_	_
26	proteins	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	as	_	ADP	_	_	_	_	_	_
32	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
33	signal	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	kinase	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	ERK	_	PROPN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	human	_	ADJ	_	Degree=Pos	_	_	_	_
43	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	contrast	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	MO7e	_	ADJ	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	GM	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	CSF	_	NOUN	_	Number=Sing	_	_	_	_
13	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
16	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
17	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	ERK	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Among	_	ADP	_	_	_	_	_	_
2	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
3	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
4	molecules	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	ERK	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	Shc	_	PROPN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	constitutively	_	ADV	_	_	_	_	_	_
11	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	Grb2	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	GM	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	CSF	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	FMLP	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	Sos1	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	c-Raf	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	GM	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	CSF	_	PROPN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	3	_	NUM	_	NumType=Card	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	TNF	_	PROPN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	FMLP	_	NOUN	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	whereas	_	SCONJ	_	_	_	_	_	_
53	all	_	DET	_	_	_	_	_	_
54	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
55	signaling	_	VERB	_	Degree=Pos	_	_	_	_
56	molecules	_	NOUN	_	Number=Plur	_	_	_	_
57	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
58	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
59	and	_	CCONJ	_	_	_	_	_	_
60	/	_	PUNCT	_	_	_	_	_	_
61	or	_	CCONJ	_	_	_	_	_	_
62	utilized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
63	by	_	ADP	_	_	_	_	_	_
64	GM	_	PROPN	_	Number=Sing	_	_	_	_
65	-	_	PUNCT	_	_	_	_	_	_
66	CSF	_	NOUN	_	Number=Sing	_	_	_	_
67	in	_	ADP	_	_	_	_	_	_
68	MO7e	_	ADJ	_	Number=Sing	_	_	_	_
69	cells	_	NOUN	_	Number=Plur	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	p38	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	constitutively	_	ADV	_	_	_	_	_	_
9	phosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	agonist	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Superoxide	_	PROPN	_	Number=Sing	_	_	_	_
2	release	_	NOUN	_	Number=Sing	_	_	_	_
3	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	FMLP	_	PROPN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	partially	_	ADV	_	_	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	PD98059	_	NOUN	_	Number=Sing	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	SB203580	_	NUM	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	ERK	_	PROPN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	p38	_	NOUN	_	Number=Sing	_	_	_	_
21	pathway	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	almost	_	ADV	_	_	_	_	_	_
26	completely	_	ADV	_	_	_	_	_	_
27	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	combination	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	both	_	CCONJ	_	_	_	_	_	_
33	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	whereas	_	SCONJ	_	_	_	_	_	_
36	PMA	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	superoxide	_	NOUN	_	Number=Sing	_	_	_	_
40	release	_	NOUN	_	Number=Sing	_	_	_	_
41	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
42	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
45	two	_	NUM	_	NumType=Card	_	_	_	_
46	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	PD98059	_	NOUN	_	Number=Sing	_	_	_	_
2	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	GM	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	CSF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	MO7e	_	ADJ	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Present	_	ADJ	_	Degree=Pos	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	trancriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	roles	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	functional	_	ADJ	_	Degree=Pos	_	_	_	_
10	roles	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	ERK	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	p38	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	agonists	_	NOUN	_	Number=Plur	_	_	_	_
28	GM	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	CSF	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	FMLP	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Possible	_	ADJ	_	Degree=Pos	_	_	_	_
2	roles	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	ERK	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003587	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Elevated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
2	cyclic	_	ADJ	_	Number=Sing	_	_	_	_
3	AMP	_	NOUN	_	Number=Sing	_	_	_	_
4	inhibits	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	Rel	_	NOUN	_	Number=Sing	_	_	_	_
7	family	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	many	_	ADJ	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
9	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	which	_	DET	_	PronType=Rel	_	_	_	_
12	agents	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	elevate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
16	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
17	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	tumor	_	NOUN	_	Number=Sing	_	_	_	_
23	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	tissue	_	NOUN	_	Number=Sing	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
34	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
35	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
36	molecule	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
44	molecule	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	genes	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	forskolin	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	dibutyryl	_	ADJ	_	Number=Sing	_	_	_	_
5	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	elevate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	independent	_	ADJ	_	Degree=Pos	_	_	_	_
13	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	tissue	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	level	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	transiently	_	ADV	_	_	_	_	_	_
12	transfected	_	VERB	_	Degree=Pos	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	THP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
22	vein	_	NOUN	_	Number=Sing	_	_	_	_
23	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	catalytic	_	ADJ	_	Degree=Pos	_	_	_	_
36	subunit	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	protein	_	NOUN	_	Number=Sing	_	_	_	_
39	kinase	_	NOUN	_	Number=Sing	_	_	_	_
40	A	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	PKA	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Elevated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
2	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
3	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	translocation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	p50/p65	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	p65	_	NOUN	_	Number=Sing	_	_	_	_
14	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	decrease	_	NOUN	_	Number=Sing	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	translocation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	p65	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	significantly	_	ADV	_	_	_	_	_	_
24	modify	_	VERB	_	VerbForm=Inf	_	_	_	_
25	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	p65	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
10	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	multimerized	_	ADJ	_	Degree=Pos	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	sites	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	p65	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	agents	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	elevate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	catalytic	_	ADJ	_	Degree=Pos	_	_	_	_
29	subunit	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	PKA	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	PKA	_	PROPN	_	Number=Sing	_	_	_	_
8	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
14	set	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	by	_	SCONJ	_	_	_	_	_	_
23	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003588	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Barr	_	PROPN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	EBV	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	BMRF1	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	early	_	ADJ	_	Degree=Pos	_	_	_	_
13	antigen	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	EA	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	D	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	EBV	_	NOUN	_	Number=Sing	_	_	_	_
24	transactivators	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	BRLF1	_	PROPN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	BZLF1	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	specific	_	ADJ	_	Degree=Pos	_	_	_	_
35	manner	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Barr	_	PROPN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	early	_	ADJ	_	Degree=Pos	_	_	_	_
7	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
8	diffuse	_	NOUN	_	Number=Sing	_	_	_	_
9	component	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	EA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	D	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	essential	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	Barr	_	PROPN	_	Number=Sing	_	_	_	_
21	virus	_	NOUN	_	Number=Sing	_	_	_	_
22	DNA	_	PROPN	_	Number=Sing	_	_	_	_
23	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	during	_	ADP	_	_	_	_	_	_
32	latent	_	ADJ	_	Degree=Pos	_	_	_	_
33	infection	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	BMRF1	_	X	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	early	_	ADJ	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	SCONJ	_	_	_	_	_	_
16	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
17	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	vitro	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	two	_	NUM	_	NumType=Card	_	_	_	_
23	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	early	_	ADJ	_	Degree=Pos	_	_	_	_
26	viral	_	ADJ	_	Degree=Pos	_	_	_	_
27	transactivators	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	BZLF1	_	PROPN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	Z	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	BRLF1	_	PROPN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	R	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	focusing	_	VERB	_	VerbForm=Ger	_	_	_	_
40	on	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	differences	_	NOUN	_	Number=Plur	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	response	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
50	cells	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	Z	_	PROPN	_	Number=Sing	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	R	_	PROPN	_	Number=Sing	_	_	_	_
8	alone	_	ADV	_	_	_	_	_	_
9	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	only	_	ADV	_	_	_	_	_	_
11	small	_	ADJ	_	Degree=Pos	_	_	_	_
12	increases	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	EA	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	D	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	whereas	_	SCONJ	_	_	_	_	_	_
21	both	_	DET	_	_	_	_	_	_
22	transactivators	_	NOUN	_	Number=Plur	_	_	_	_
23	together	_	ADV	_	_	_	_	_	_
24	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	large	_	ADJ	_	Degree=Pos	_	_	_	_
27	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	effect	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	Z	_	PROPN	_	Number=Sing	_	_	_	_
7	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
8	alone	_	ADV	_	_	_	_	_	_
9	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
11	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	EA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	D	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	;	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	effect	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	R	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	Z	_	PROPN	_	Number=Sing	_	_	_	_
25	together	_	ADV	_	_	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	no	_	ADV	_	_	_	_	_	_
28	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
29	than	_	ADP	_	_	_	_	_	_
30	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	Z	_	PROPN	_	Number=Sing	_	_	_	_
33	alone	_	ADV	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Deletional	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	site	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	EA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	D	_	PROPN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	potential	_	ADJ	_	Degree=Pos	_	_	_	_
21	AP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	essential	_	ADJ	_	Degree=Pos	_	_	_	_
29	role	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	Z	_	PROPN	_	Number=Sing	_	_	_	_
32	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	although	_	SCONJ	_	_	_	_	_	_
35	sequences	_	NOUN	_	Number=Plur	_	_	_	_
36	further	_	ADJ	_	Degree=Pos	_	_	_	_
37	upstream	_	NOUN	_	Number=Sing	_	_	_	_
38	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	also	_	ADV	_	_	_	_	_	_
40	important	_	ADJ	_	Degree=Pos	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	only	_	ADV	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
8	sequences	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	Z/R	_	NOUN	_	Number=Sing	_	_	_	_
16	combination	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	dispensable	_	ADJ	_	Degree=Pos	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	EA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	D	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	BMRF1	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	promoter	_	VERB	_	VerbForm=Ger	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	Z	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	R	_	PROPN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	type	_	NOUN	_	Number=Sing	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
25	different	_	ADJ	_	Degree=Pos	_	_	_	_
26	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	each	_	DET	_	_	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	type	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003589	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	6	_	NUM	_	NumType=Card	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
7	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
8	hyperplasia	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
11	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	angioimmunoblastic	_	ADJ	_	Number=Sing	_	_	_	_

1	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
2	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	hyperplastic	_	ADJ	_	Degree=Pos	_	_	_	_
5	germinal	_	ADJ	_	Degree=Pos	_	_	_	_
6	centers	_	NOUN	_	Number=Plur	_	_	_	_
7	:	_	PUNCT	_	_	_	_	_	_
8	heterogeneity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	intrafollicular	_	ADJ	_	Degree=Pos	_	_	_	_
11	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	altered	_	VERB	_	Degree=Pos	_	_	_	_
15	distribution	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	angioimmunoblastic	_	ADJ	_	Number=Sing	_	_	_	_

1	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
2	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	product	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	phosphoprotein	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	independently	_	ADV	_	_	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	6	_	NUM	_	NumType=Card	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	lymph	_	NOUN	_	Number=Sing	_	_	_	_
3	nodes	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	6	_	NUM	_	NumType=Card	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	germinal	_	ADJ	_	Degree=Pos	_	_	_	_
15	center	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	GC	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	10	_	NUM	_	NumType=Card	_	_	_	_
24	%	_	SYM	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	15	_	NUM	_	NumType=Card	_	_	_	_
27	%	_	SYM	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	CD3	_	NOUN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	CD4	_	NOUN	_	Number=Sing	_	_	_	_
32	+	_	SYM	_	_	_	_	_	_
33	intrafollicular	_	ADJ	_	Degree=Pos	_	_	_	_
34	T	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Interfollicular	_	ADJ	_	Degree=Pos	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	negative	_	ADJ	_	Degree=Pos	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	except	_	ADP	_	_	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	rare	_	ADJ	_	Degree=Pos	_	_	_	_
14	CD3+/	_	NOUN	_	Number=Sing	_	_	_	_
15	CD4	_	PROPN	_	Number=Sing	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	cases	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	angioimmunoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
8	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
9	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	AITL	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	hyperplastic	_	ADJ	_	Degree=Pos	_	_	_	_
15	GCs	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	AITL	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	GC	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	borders	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	enlarged	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
28	GCs	_	NOUN	_	Number=Plur	_	_	_	_
29	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	ill	_	ADV	_	Degree=Pos	_	_	_	_
31	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	features	_	NOUN	_	Number=Plur	_	_	_	_
35	suggestive	_	ADJ	_	Degree=Pos	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	outward	_	ADJ	_	Degree=Pos	_	_	_	_
39	migration	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	GC	_	PROPN	_	Number=Sing	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	to	_	PART	_	_	_	_	_	_
44	surrounding	_	VERB	_	VerbForm=Ger	_	_	_	_
45	interfollicular	_	ADJ	_	Degree=Pos	_	_	_	_
46	zones	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	prompted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
7	borders	_	NOUN	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	6	_	NUM	_	NumType=Card	_	_	_	_
12	staining	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
15	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
16	hyperplasias	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
19	lymphomas	_	NOUN	_	Number=Plur	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	compare	_	VERB	_	VerbForm=Inf	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	AITL	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	GC.	_	NOUN	_	Number=Sing	_	_	_	_
26	MATERIALS	_	NOUN	_	Number=Plur	_	_	_	_
27	AND	_	CCONJ	_	_	_	_	_	_
28	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
29	:	_	PUNCT	_	_	_	_	_	_
30	Formalin	_	ADJ	_	Degree=Pos	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	fixed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	paraffin	_	NOUN	_	Number=Sing	_	_	_	_
34	sections	_	NOUN	_	Number=Plur	_	_	_	_
35	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	immunostaining	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	6	_	NUM	_	NumType=Card	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Six	_	NUM	_	NumType=Card	_	_	_	_
2	cases	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	AITL	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	GC	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	12	_	NUM	_	NumType=Card	_	_	_	_
9	nonspecific	_	ADJ	_	Degree=Pos	_	_	_	_
10	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
11	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
12	hyperplasia	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	FH	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	7	_	NUM	_	NumType=Card	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	adenopathy	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	10	_	NUM	_	NumType=Card	_	_	_	_
22	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
23	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	FL	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	8	_	NUM	_	NumType=Card	_	_	_	_
30	typical	_	ADJ	_	Degree=Pos	_	_	_	_
31	AITL	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	ie	_	X	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	AITL	_	NOUN	_	Number=Sing	_	_	_	_
36	without	_	ADP	_	_	_	_	_	_
37	GC	_	PROPN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Double	_	ADJ	_	Degree=Pos	_	_	_	_
2	staining	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6/CD20	_	NUM	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	6/CD3	_	NUM	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	CD57	_	PROPN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	cases	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	In	_	ADP	_	_	_	_	_	_
4	FH	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	HIV	_	PROPN	_	Number=Sing	_	_	_	_
7	adenopathy	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	staining	_	VERB	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	densely	_	ADV	_	_	_	_	_	_
16	populated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	GCs	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	well	_	ADV	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	defined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	regular	_	ADJ	_	Degree=Pos	_	_	_	_
24	GC	_	NOUN	_	Number=Sing	_	_	_	_
25	borders	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	whereas	_	SCONJ	_	_	_	_	_	_
28	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	6	_	NUM	_	NumType=Card	_	_	_	_
31	+	_	SYM	_	_	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	rare	_	ADJ	_	Degree=Pos	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	interfollicular	_	ADJ	_	Degree=Pos	_	_	_	_
38	areas	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	occasional	_	ADJ	_	Degree=Pos	_	_	_	_
3	GC	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	ill	_	ADV	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	defined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	border	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	invariably	_	ADV	_	_	_	_	_	_
12	surrounded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	broad	_	ADJ	_	Degree=Pos	_	_	_	_
16	mantle	_	NOUN	_	Number=Sing	_	_	_	_
17	zone	_	NOUN	_	Number=Sing	_	_	_	_
18	;	_	PUNCT	_	_	_	_	_	_
19	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	indistinct	_	ADJ	_	Degree=Pos	_	_	_	_
22	mantle	_	NOUN	_	Number=Sing	_	_	_	_
23	zones	_	NOUN	_	Number=Plur	_	_	_	_
24	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	well	_	ADV	_	Degree=Pos	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	defined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	regular	_	ADJ	_	Degree=Pos	_	_	_	_
30	borders	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	FL	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	follicles	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	densely	_	ADV	_	_	_	_	_	_
7	populated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	borders	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	irregular	_	ADJ	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	some	_	DET	_	_	_	_	_	_
17	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	6	_	NUM	_	NumType=Card	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	interfollicular	_	ADJ	_	Degree=Pos	_	_	_	_
25	zones	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	AITL	_	PROPN	_	Number=Sing	_	_	_	_
3	/	_	PUNCT	_	_	_	_	_	_
4	GC	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	GCs	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	less	_	ADV	_	Degree=Cmp	_	_	_	_
9	dense	_	ADJ	_	Degree=Pos	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	GC	_	NOUN	_	Number=Sing	_	_	_	_
12	borders	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	ill	_	ADV	_	Degree=Pos	_	_	_	_
15	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	irregular	_	ADJ	_	Degree=Pos	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	number	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	interfollicular	_	ADJ	_	Degree=Pos	_	_	_	_
24	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	6	_	NUM	_	NumType=Card	_	_	_	_
27	+	_	SYM	_	_	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	markedly	_	ADV	_	_	_	_	_	_
31	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Double	_	ADJ	_	Degree=Pos	_	_	_	_
2	staining	_	NOUN	_	Number=Sing	_	_	_	_
3	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	interfollicular	_	ADJ	_	Degree=Pos	_	_	_	_
7	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	6	_	NUM	_	NumType=Card	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	AITL	_	PROPN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	GC	_	NOUN	_	Number=Sing	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	Bcl6+/CD3+/CD20-/CD57	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CD3	_	PROPN	_	Number=Sing	_	_	_	_
4	+	_	SYM	_	_	_	_	_	_
5	intrafollicular	_	ADJ	_	Degree=Pos	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	depleted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	AITL	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	GC	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	whereas	_	SCONJ	_	_	_	_	_	_
11	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	abundant	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	FH	_	PROPN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Intrafollicular	_	ADJ	_	Degree=Pos	_	_	_	_
2	CD57	_	NOUN	_	Number=Sing	_	_	_	_
3	+	_	SYM	_	_	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	stain	_	VERB	_	VerbForm=Inf	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	6	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	depleted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	AITL	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	GC	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	typical	_	ADJ	_	Degree=Pos	_	_	_	_
3	AITL	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	some	_	DET	_	_	_	_	_	_
6	neoplastic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	positive	_	ADJ	_	Degree=Pos	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	showing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	variable	_	ADJ	_	Degree=Pos	_	_	_	_
17	degrees	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	staining	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	1	_	X	_	_	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	GCs	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	AITL	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	GC	_	NOUN	_	Number=Sing	_	_	_	_
11	differed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	other	_	ADJ	_	Degree=Pos	_	_	_	_
16	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
17	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
18	hyperplasias	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
21	lymphomas	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	staining	_	NOUN	_	Number=Sing	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	6	_	NUM	_	NumType=Card	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	useful	_	ADJ	_	Degree=Pos	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	discern	_	VERB	_	VerbForm=Inf	_	_	_	_
33	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	2	_	X	_	_	_	_	_	_
3	)	_	PUNCT	_	_	_	_	_	_
4	Intrafollicular	_	ADJ	_	Degree=Pos	_	_	_	_
5	CD3	_	NOUN	_	Number=Sing	_	_	_	_
6	+	_	SYM	_	_	_	_	_	_

1	T	_	X	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	many	_	ADJ	_	Degree=Pos	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Int	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	positive	_	ADJ	_	Degree=Pos	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	SYM	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	markedly	_	ADV	_	_	_	_	_	_
17	depleted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	AITL	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	GC	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	interfollicular	_	ADJ	_	Degree=Pos	_	_	_	_
26	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	6+/	_	NUM	_	NumType=Card	_	_	_	_
29	CD3	_	NOUN	_	Number=Sing	_	_	_	_
30	+	_	SYM	_	_	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	outward	_	ADJ	_	Degree=Pos	_	_	_	_
36	migration	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	intrafollicular	_	ADJ	_	Degree=Pos	_	_	_	_
39	T	_	NOUN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
43	condition	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	3	_	X	_	_	_	_	_	_
3	)	_	PUNCT	_	_	_	_	_	_
4	Interfollicular	_	ADJ	_	Degree=Pos	_	_	_	_
5	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	6+/	_	NUM	_	NumType=Card	_	_	_	_
8	CD3	_	NOUN	_	Number=Sing	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	AITL	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	GC	_	NOUN	_	Number=Sing	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	too	_	ADV	_	_	_	_	_	_
17	numerous	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	accounted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	migration	_	NOUN	_	Number=Sing	_	_	_	_
24	alone	_	ADV	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
27	local	_	ADJ	_	Degree=Pos	_	_	_	_
28	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	4	_	X	_	_	_	_	_	_
3	)	_	PUNCT	_	_	_	_	_	_
4	Intrafollicular	_	ADJ	_	Degree=Pos	_	_	_	_
5	CD57	_	NOUN	_	Number=Sing	_	_	_	_
6	+	_	SYM	_	_	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	negative	_	ADJ	_	Degree=Pos	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	heterogeneity	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	intrafollicular	_	ADJ	_	Degree=Pos	_	_	_	_
20	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
21	population	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	5	_	X	_	_	_	_	_	_
3	)	_	PUNCT	_	_	_	_	_	_
4	Some	_	DET	_	_	_	_	_	_
5	neoplastic	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	AITL	_	PROPN	_	Number=Sing	_	_	_	_
9	stained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	up	_	ADP	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	regulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	6	_	NUM	_	NumType=Card	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	tumor	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003593	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Staphylococcal	_	ADJ	_	Degree=Pos	_	_	_	_
2	enterotoxins	_	NOUN	_	Number=Plur	_	_	_	_
3	modulate	_	VERB	_	Degree=Pos	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	ligand	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
13	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	Janus	_	PROPN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	3	_	NUM	_	NumType=Card	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	Jak3	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	signal	_	NOUN	_	Number=Sing	_	_	_	_
27	transducers	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	activators	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	Stat	_	PROPN	_	Number=Sing	_	_	_	_
34	proteins	_	NOUN	_	Number=Plur	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Staphylococcal	_	ADJ	_	Degree=Pos	_	_	_	_
2	enterotoxins	_	NOUN	_	Number=Plur	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	SE	_	X	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	appropriate	_	ADJ	_	Degree=Pos	_	_	_	_
12	variable	_	ADJ	_	Degree=Pos	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	chain	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	V	_	PROPN	_	Number=Sing	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	receptors	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	several	_	ADJ	_	Degree=Pos	_	_	_	_
14	autoimmune	_	NOUN	_	Number=Sing	_	_	_	_
15	diseases	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Depending	_	VERB	_	VerbForm=Ger	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	signals	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	SE	_	X	_	Number=Sing	_	_	_	_
7	induce	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
8	either	_	CCONJ	_	_	_	_	_	_
9	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	anergy	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	SE	_	PRON	_	Number=Sing	_	_	_	_
5	can	_	AUX	_	VerbForm=Fin	_	_	_	_
6	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	_	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	nonresponsive	_	ADJ	_	Degree=Pos	_	_	_	_
17	state	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	SE	_	PRON	_	Number=Sing	_	_	_	_
7	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
8	dynamic	_	ADJ	_	Degree=Pos	_	_	_	_
9	changes	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	signal	_	NOUN	_	Number=Sing	_	_	_	_
16	transduction	_	NOUN	_	Number=Sing	_	_	_	_
17	through	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2R	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	beta	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	gamma	_	NOUN	_	Number=Sing	_	_	_	_
31	chains	_	NOUN	_	Number=Plur	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2R	_	PROPN	_	Number=Sing	_	_	_	_
36	beta	_	PROPN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	IL	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	2R	_	NUM	_	Number=Sing	_	_	_	_
41	gamma	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	human	_	ADJ	_	Degree=Pos	_	_	_	_
45	antigen	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	specific	_	ADJ	_	Degree=Pos	_	_	_	_
48	CD4	_	NOUN	_	Number=Sing	_	_	_	_
49	+	_	SYM	_	_	_	_	_	_

1	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
2	lines	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	after	_	ADP	_	_	_	_	_	_
4	4	_	NUM	_	NumType=Card	_	_	_	_
5	hr	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	exposure	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	SEA	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	SEB	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2R	_	NUM	_	Number=Sing	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	down	_	ADV	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2R	_	PROPN	_	Number=Sing	_	_	_	_
28	gamma	_	NOUN	_	Number=Sing	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	slightly	_	ADV	_	_	_	_	_	_
31	up	_	ADJ	_	_	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	regulated	_	VERB	_	Degree=Pos	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	while	_	SCONJ	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2R	_	PROPN	_	Number=Sing	_	_	_	_
39	alpha	_	PROPN	_	Number=Sing	_	_	_	_
40	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	largely	_	ADV	_	_	_	_	_	_
42	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	changes	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	composition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2Rs	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
21	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	Janus	_	PROPN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
28	kinase	_	NOUN	_	Number=Sing	_	_	_	_
29	3	_	NUM	_	NumType=Card	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	Jak3	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	signal	_	NOUN	_	Number=Sing	_	_	_	_
35	transducers	_	NOUN	_	Number=Plur	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	activators	_	NOUN	_	Number=Plur	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	parallel	_	ADJ	_	Degree=Pos	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	significantly	_	ADV	_	_	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	16	_	NUM	_	NumType=Card	_	_	_	_
3	hr	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	exposure	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	SE	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2R	_	NUM	_	Number=Sing	_	_	_	_
15	beta	_	NOUN	_	Number=Sing	_	_	_	_
16	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	low	_	ADJ	_	Degree=Pos	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	while	_	SCONJ	_	_	_	_	_	_
20	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	IL2R	_	PROPN	_	Number=Sing	_	_	_	_
23	alpha	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	IL2R	_	PROPN	_	Number=Sing	_	_	_	_
26	gamma	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	further	_	ADV	_	_	_	_	_	_
29	up	_	ADP	_	_	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	regulated	_	ADJ	_	Degree=Pos	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	ligand	_	ADJ	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
38	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	Stat	_	PROPN	_	Number=Sing	_	_	_	_
43	proteins	_	NOUN	_	Number=Plur	_	_	_	_
44	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
45	partly	_	ADV	_	_	_	_	_	_
46	normalized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Yet	_	CCONJ	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
9	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	profoundly	_	ADV	_	_	_	_	_	_
11	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
16	events	_	NOUN	_	Number=Plur	_	_	_	_
17	other	_	ADJ	_	Degree=Pos	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	Stat	_	PROPN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	also	_	ADV	_	_	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	changed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	following	_	VERB	_	VerbForm=Ger	_	_	_	_
28	SE	_	PROPN	_	Number=Sing	_	_	_	_
29	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	SE	_	PRON	_	Number=Sing	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2R	_	NUM	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	signal	_	VERB	_	Number=Sing	_	_	_	_
17	transduction	_	NOUN	_	Number=Sing	_	_	_	_
18	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	Jak	_	PROPN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	Stat	_	PROPN	_	Number=Sing	_	_	_	_
23	pathway	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	CD4	_	PROPN	_	Number=Sing	_	_	_	_
26	+	_	SYM	_	_	_	_	_	_

1	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
2	lines	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003595	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	56-59	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kilodalton	_	NOUN	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	untransformed	_	ADJ	_	Degree=Pos	_	_	_	_
9	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	complexes	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	unique	_	ADJ	_	Degree=Pos	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	exists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	complex	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	both	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	70	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	90	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kilodalton	_	NOUN	_	Number=Sing	_	_	_	_
32	heat	_	NOUN	_	Number=Sing	_	_	_	_
33	shock	_	NOUN	_	Number=Sing	_	_	_	_
34	proteins	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	9S	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	untransformed	_	ADJ	_	Degree=Pos	_	_	_	_
10	progestin	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	estrogen	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	androgen	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	complexes	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	rabbit	_	NOUN	_	Number=Sing	_	_	_	_
22	uterine	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	liver	_	NOUN	_	Number=Sing	_	_	_	_
25	cytosols	_	NOUN	_	Number=Plur	_	_	_	_
26	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	59	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kDa	_	NOUN	_	Number=Sing	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	[	_	PUNCT	_	_	_	_	_	_
33	Tai	_	PROPN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	P.K.	_	PROPN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	Maeda	_	PROPN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	Y.	_	PROPN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	Nakao	_	PROPN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	K.	_	PROPN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	Wakim	_	PROPN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	N.G.	_	PROPN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	Duhring	_	PROPN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	J.L.	_	PROPN	_	Number=Sing	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	&	_	CCONJ	_	_	_	_	_	_
54	Faber	_	PROPN	_	Number=Sing	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	L.E.	_	PROPN	_	Number=Sing	_	_	_	_
57	(	_	PUNCT	_	_	_	_	_	_
58	1986	_	NUM	_	NumType=Card	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	Biochemistry	_	PROPN	_	Number=Sing	_	_	_	_
61	25	_	NUM	_	NumType=Card	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	5269	_	NUM	_	NumType=Card	_	_	_	_
64	-	_	SYM	_	_	_	_	_	_
65	5275	_	NUM	_	NumType=Card	_	_	_	_
66	]	_	PUNCT	_	_	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	work	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	monoclonal	_	ADJ	_	Number=Sing	_	_	_	_
9	antibody	_	NOUN	_	Number=Sing	_	_	_	_
10	KN	_	PROPN	_	Number=Sing	_	_	_	_
11	382/EC1	_	NUM	_	NumType=Card	_	_	_	_
12	raised	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	against	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	rabbit	_	NOUN	_	Number=Sing	_	_	_	_
16	59	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kDa	_	NOUN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	reacts	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	9S	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	untransformed	_	ADJ	_	Degree=Pos	_	_	_	_
25	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	complexes	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
30	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	human	_	ADJ	_	Degree=Pos	_	_	_	_
33	IM	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	9	_	NUM	_	NumType=Card	_	_	_	_
36	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	but	_	CCONJ	_	_	_	_	_	_
38	not	_	ADV	_	_	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	4S	_	NOUN	_	Number=Sing	_	_	_	_
41	salt	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	receptors	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	recognized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	EC1	_	PROPN	_	Number=Sing	_	_	_	_
8	antibody	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	56	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kDa	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	p56	_	NUM	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	moderate	_	ADJ	_	Degree=Pos	_	_	_	_
20	abundance	_	NOUN	_	Number=Sing	_	_	_	_
21	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	predominantly	_	ADV	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	indirect	_	ADJ	_	Degree=Pos	_	_	_	_
28	immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	at	_	ADV	_	_	_	_	_	_
4	least	_	ADV	_	Degree=Sup	_	_	_	_
5	six	_	NUM	_	NumType=Card	_	_	_	_
6	isomorphs	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	p56	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dimensional	_	ADJ	_	Degree=Pos	_	_	_	_
13	gel	_	NOUN	_	Number=Sing	_	_	_	_
14	analysis	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	N-	_	PUNCT	_	_	_	_	_	_
2	Terminal	_	NOUN	_	Number=Sing	_	_	_	_
3	sequencing	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	20	_	NUM	_	NumType=Card	_	_	_	_
6	amino	_	ADJ	_	Degree=Pos	_	_	_	_
7	acids	_	NOUN	_	Number=Plur	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	p56	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	unique	_	ADJ	_	Degree=Pos	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	p56	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	immunoadsorbed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	IM	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	9	_	NUM	_	NumType=Card	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	70	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	90	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kDa	_	NOUN	_	Number=Sing	_	_	_	_
20	heat	_	NOUN	_	Number=Sing	_	_	_	_
21	shock	_	NOUN	_	Number=Sing	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	coadsorbed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	immune	_	ADJ	_	Degree=Pos	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	specific	_	ADJ	_	Degree=Pos	_	_	_	_
30	manner	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Neither	_	DET	_	_	_	_	_	_
2	heat	_	NOUN	_	Number=Sing	_	_	_	_
3	shock	_	NOUN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	reacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	directly	_	ADV	_	_	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	EC1	_	NOUN	_	Number=Sing	_	_	_	_
10	antibody	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	p56	_	NUM	_	Number=Sing	_	_	_	_
5	exists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
11	order	_	NOUN	_	Number=Sing	_	_	_	_
12	complex	_	NOUN	_	Number=Sing	_	_	_	_
13	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	hsp70	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	hsp90	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	both	_	DET	_	_	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Int	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	turn	_	NOUN	_	Number=Sing	_	_	_	_
23	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
25	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	untransformed	_	ADJ	_	Degree=Pos	_	_	_	_
31	steroid	_	NOUN	_	Number=Sing	_	_	_	_
32	receptors	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003596	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Oncogenicity	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	papillomavirus	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	adenovirus	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	resistance	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	lysis	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	natural	_	ADJ	_	Degree=Pos	_	_	_	_
18	killer	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	reasons	_	NOUN	_	Number=Plur	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	dissimilar	_	ADJ	_	Degree=Pos	_	_	_	_
6	oncogenicities	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	adenoviruses	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	papillomaviruses	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	HPV	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	humans	_	NOUN	_	Number=Plur	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	may	_	AUX	_	VerbForm=Fin	_	_	_	_
22	relate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	differences	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	capacities	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	E1A	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	E7	_	NUM	_	Number=Sing	_	_	_	_
33	proteins	_	NOUN	_	Number=Plur	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	target	_	VERB	_	VerbForm=Inf	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	rejection	_	NOUN	_	Number=Sing	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	host	_	NOUN	_	Number=Sing	_	_	_	_
42	natural	_	ADJ	_	Degree=Pos	_	_	_	_
43	killer	_	NOUN	_	Number=Sing	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	NK	_	PROPN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	cell	_	NOUN	_	Number=Sing	_	_	_	_
48	response	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	one	_	NUM	_	NumType=Card	_	_	_	_
3	test	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	abilities	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	E1A	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	E7	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	fibroblastic	_	NOUN	_	Number=Sing	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	keratinocyte	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	be	_	AUX	_	VerbForm=Inf	_	_	_	_
29	selectively	_	ADV	_	_	_	_	_	_
30	killed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	either	_	CCONJ	_	_	_	_	_	_
33	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	interferon	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	IFN	_	PROPN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	activated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
41	NK	_	PROPN	_	Number=Sing	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Cells	_	NOUN	_	Number=Plur	_	_	_	_
2	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	E1A	_	PROPN	_	Number=Sing	_	_	_	_
5	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	selectively	_	ADV	_	_	_	_	_	_
8	killed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
11	NK	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	while	_	SCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	same	_	ADJ	_	Degree=Pos	_	_	_	_
17	parental	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	HPV	_	NOUN	_	Number=Sing	_	_	_	_
23	type	_	NOUN	_	Number=Sing	_	_	_	_
24	16	_	NUM	_	NumType=Card	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	HPV	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	16	_	NUM	_	NumType=Card	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	HPV	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	18	_	NUM	_	NumType=Card	_	_	_	_
34	E7	_	NUM	_	Number=Sing	_	_	_	_
35	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
36	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	NK	_	PROPN	_	Number=Sing	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	lysis	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IFN	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	NK	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	selectively	_	ADV	_	_	_	_	_	_
11	kill	_	VERB	_	VerbForm=Inf	_	_	_	_
12	virally	_	ADV	_	_	_	_	_	_
13	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	IFN	_	PROPN	_	Number=Sing	_	_	_	_
18	's	_	PART	_	_	_	_	_	_
19	ability	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
22	resistance	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	NK	_	PROPN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	lysis	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	normal	_	ADJ	_	Degree=Pos	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	i.e.	_	X	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	non-viral	_	ADJ	_	Degree=Pos	_	_	_	_
33	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	expressing	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	but	_	CCONJ	_	_	_	_	_	_
38	not	_	ADV	_	_	_	_	_	_
39	virally	_	ADV	_	_	_	_	_	_
40	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	E1A	_	PROPN	_	Number=Sing	_	_	_	_
2	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	IFN	_	PROPN	_	Number=Sing	_	_	_	_
4	's	_	PART	_	_	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cytolytic	_	ADJ	_	Degree=Pos	_	_	_	_
8	resistance	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	selective	_	ADJ	_	Degree=Pos	_	_	_	_
14	lysis	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	adenovirus	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	IFN	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	activated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
24	NK	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	extent	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IFN	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	NK	_	PROPN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	killing	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	E1A	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	proportional	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	level	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	E1A	_	PROPN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	ability	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	E1A	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	block	_	VERB	_	VerbForm=Inf	_	_	_	_
32	IFN	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	target	_	NOUN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	E7	_	PROPN	_	Number=Sing	_	_	_	_
5	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	neither	_	CCONJ	_	_	_	_	_	_
7	IFN	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	nor	_	CCONJ	_	_	_	_	_	_
13	IFN	_	PROPN	_	Number=Sing	_	_	_	_
14	's	_	PART	_	_	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	cytolytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	resistance	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	thereby	_	ADV	_	_	_	_	_	_
21	precluding	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	selective	_	ADJ	_	Degree=Pos	_	_	_	_
24	lysis	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	HPV	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	IFN	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	activated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
34	NK	_	PROPN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	E1A	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	marks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	destruction	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	host	_	NOUN	_	Number=Sing	_	_	_	_
13	NK	_	PROPN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	whereas	_	SCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	E7	_	PROPN	_	Number=Sing	_	_	_	_
20	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
21	lacks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003597	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cloning	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	NK	_	PROPN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	codes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	high	_	ADJ	_	Degree=Pos	_	_	_	_
17	proline	_	NOUN	_	Number=Sing	_	_	_	_
18	content	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
3	clone	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	B4	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	natural	_	ADJ	_	Degree=Pos	_	_	_	_
14	killer	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	NK	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	minus	_	CCONJ	_	_	_	_	_	_
19	T	_	NOUN	_	NumType=Card	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	subtractive	_	ADJ	_	Degree=Pos	_	_	_	_
22	library	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	B4	_	PROPN	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	clone	_	NOUN	_	Number=Sing	_	_	_	_
6	coded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	2061	_	NUM	_	NumType=Card	_	_	_	_
12	bp	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	length	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	deduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	327	_	NUM	_	NumType=Card	_	_	_	_
6	aa	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	calculated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
12	mass	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	35.2	_	NUM	_	NumType=Card	_	_	_	_
15	kDa	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Searching	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	B4	_	NUM	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	DNA	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	sequences	_	NOUN	_	Number=Plur	_	_	_	_
10	against	_	ADP	_	_	_	_	_	_
11	various	_	ADJ	_	Degree=Pos	_	_	_	_
12	databases	_	NOUN	_	Number=Plur	_	_	_	_
13	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	no	_	DET	_	_	_	_	_	_
15	high	_	ADJ	_	Degree=Pos	_	_	_	_
16	homology	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	sequences	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	B4	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	unusually	_	ADV	_	_	_	_	_	_
9	high	_	ADJ	_	Degree=Pos	_	_	_	_
10	proline	_	NOUN	_	Number=Sing	_	_	_	_
11	content	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	13	_	NUM	_	NumType=Card	_	_	_	_
14	%	_	SYM	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	putative	_	ADJ	_	Degree=Pos	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	targeting	_	NOUN	_	Number=Sing	_	_	_	_
22	sequence	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	several	_	ADJ	_	Degree=Pos	_	_	_	_
27	SPXX	_	NOUN	_	Number=Sing	_	_	_	_
28	motifs	_	NOUN	_	Number=Plur	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	frequently	_	ADV	_	_	_	_	_	_
32	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
36	proteins	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	stretches	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	prolines	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	B4	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	closely	_	ADV	_	_	_	_	_	_
12	resembles	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	ligand	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	SH3	_	NOUN	_	Number=Sing	_	_	_	_
19	domains	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
3	data	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	B4	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	hepatoma	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	line	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	also	_	ADV	_	_	_	_	_	_
25	weakly	_	ADV	_	_	_	_	_	_
26	transcribed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	absent	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	variety	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	other	_	ADJ	_	Degree=Pos	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
3	antiserum	_	NOUN	_	Number=Sing	_	_	_	_
4	raised	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	against	_	ADP	_	_	_	_	_	_
6	recombinant	_	NOUN	_	Number=Sing	_	_	_	_
7	B4	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	32	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	34	_	NUM	_	NumType=Card	_	_	_	_
15	kDa	_	NOUN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003598	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Visualization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	p50	_	NOUN	_	Number=Sing	_	_	_	_
10	subunit	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
16	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	germinal	_	ADJ	_	Degree=Pos	_	_	_	_
20	centers	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	50	_	NUM	_	NumType=Card	_	_	_	_
8	kDa	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	65	_	NUM	_	NumType=Card	_	_	_	_
11	kDa	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	positive	_	ADJ	_	Degree=Pos	_	_	_	_
26	regulation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	various	_	ADJ	_	Degree=Pos	_	_	_	_
29	immune	_	ADJ	_	Degree=Pos	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	aim	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
9	whether	_	SCONJ	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	PROPN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	related	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	particular	_	ADJ	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	step	_	NOUN	_	Number=Sing	_	_	_	_
26	during	_	ADP	_	_	_	_	_	_
27	immunopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	situ	_	NOUN	_	Number=Sing	_	_	_	_
4	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	sections	_	NOUN	_	Number=Plur	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	non	_	X	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	hyperplastic	_	ADJ	_	Degree=Pos	_	_	_	_
11	lymph	_	NOUN	_	Number=Sing	_	_	_	_
12	nodes	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	105	_	NUM	_	NumType=Card	_	_	_	_
22	kDa	_	NOUN	_	Number=Sing	_	_	_	_
23	precursor	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	p50	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	light	_	NOUN	_	Number=Sing	_	_	_	_
31	zone	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	germinal	_	ADJ	_	Degree=Pos	_	_	_	_
34	centers	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	network	_	NOUN	_	Number=Sing	_	_	_	_
39	aspect	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	which	_	PRON	_	PronType=Rel	_	_	_	_
42	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	involvement	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
47	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	FDC	_	PROPN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	immunohistochemistry	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	p50	_	PROPN	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	FDC	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	confirming	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	involvement	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	FDC	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	p50	_	PROPN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	all	_	DET	_	_	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	focused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
6	study	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	FDC	_	PROPN	_	Number=Sing	_	_	_	_
10	clusters	_	NOUN	_	Number=Plur	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	normal	_	ADJ	_	Degree=Pos	_	_	_	_
13	tonsils	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	showed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	tissue	_	NOUN	_	Number=Sing	_	_	_	_
5	sections	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	detected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	p50	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	FDC	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Nuclei	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	FDC	_	PROPN	_	Number=Sing	_	_	_	_
6	clusters	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	negative	_	ADJ	_	Degree=Pos	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	next	_	ADV	_	_	_	_	_	_
3	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	p65	_	NUM	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	c	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	Rel	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	FDC	_	PROPN	_	Number=Sing	_	_	_	_
13	clusters	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	p65	_	NOUN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	FDC	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	whereas	_	SCONJ	_	_	_	_	_	_
11	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	negative	_	ADJ	_	Degree=Pos	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	p65	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	some	_	DET	_	_	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	only	_	ADV	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	FDC	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	context	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	B	_	NOUN	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	immunopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
17	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	FDC	_	PROPN	_	Number=Sing	_	_	_	_
20	clusters	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	p50	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	mainly	_	ADV	_	_	_	_	_	_
25	related	_	ADJ	_	Degree=Pos	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	FDC	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	massive	_	ADJ	_	Degree=Pos	_	_	_	_
31	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	whereas	_	SCONJ	_	_	_	_	_	_
37	p65	_	NOUN	_	Number=Sing	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	scattered	_	ADJ	_	Degree=Pos	_	_	_	_
43	manner	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	c	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	Rel	_	NOUN	_	Number=Sing	_	_	_	_
53	protein	_	NOUN	_	Number=Sing	_	_	_	_
54	exclusively	_	ADV	_	_	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
58	of	_	ADP	_	_	_	_	_	_
59	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
60	from	_	ADP	_	_	_	_	_	_
61	FDC	_	PROPN	_	Number=Sing	_	_	_	_
62	clusters	_	NOUN	_	Number=Plur	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	subunits	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	c	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	Rel	_	NOUN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	different	_	ADJ	_	Degree=Pos	_	_	_	_
21	roles	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	different	_	ADJ	_	Degree=Pos	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	types	_	NOUN	_	Number=Plur	_	_	_	_
26	during	_	ADP	_	_	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	immunopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003607	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
2	functions	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	chromatin	_	ADJ	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	manner	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	augment	_	VERB	_	VerbForm=Inf	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	globin	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	5	_	NUM	_	NumType=Card	_	_	_	_
3	'	_	PUNCT	_	_	_	_	_	_
4	flanking	_	VERB	_	Number=Sing	_	_	_	_
5	region	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	globin	_	PROPN	_	Degree=Pos	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	highly	_	ADV	_	_	_	_	_	_
15	G	_	ADJ	_	Degree=Pos	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_
17	C	_	PROPN	_	Number=Sing	_	_	_	_
18	rich	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
22	copies	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	consensus	_	NOUN	_	Number=Sing	_	_	_	_
26	sequence	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	G	_	NOUN	_	Number=Sing	_	_	_	_
8	+	_	SYM	_	_	_	_	_	_
9	C	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	rich	_	ADJ	_	Degree=Pos	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	SCONJ	_	_	_	_	_	_
14	augmenting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	globin	_	VERB	_	Degree=Pos	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	presence	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	far	_	ADJ	_	Degree=Pos	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	globin	_	PROPN	_	Number=Sing	_	_	_	_
31	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	HS	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	40	_	NUM	_	NumType=Card	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	transiently	_	ADV	_	_	_	_	_	_
6	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	deletion	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	globin	_	PROPN	_	Number=Sing	_	_	_	_
16	G	_	PROPN	_	Number=Sing	_	_	_	_
17	+	_	SYM	_	_	_	_	_	_
18	C	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	rich	_	ADJ	_	Degree=Pos	_	_	_	_
21	5	_	NUM	_	NumType=Card	_	_	_	_
22	'	_	PUNCT	_	_	_	_	_	_
23	flanking	_	VERB	_	Number=Sing	_	_	_	_
24	region	_	NOUN	_	Number=Sing	_	_	_	_
25	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	no	_	DET	_	_	_	_	_	_
27	effect	_	NOUN	_	Number=Sing	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	globin	_	ADJ	_	Number=Sing	_	_	_	_
32	promoter	_	NOUN	_	Number=Sing	_	_	_	_
33	activity	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	upon	_	ADP	_	_	_	_	_	_
4	stable	_	ADJ	_	Degree=Pos	_	_	_	_
5	integration	_	NOUN	_	Number=Sing	_	_	_	_
6	into	_	ADP	_	_	_	_	_	_
7	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	deletion	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	nearly	_	ADV	_	_	_	_	_	_
16	90	_	NUM	_	NumType=Card	_	_	_	_
17	%	_	SYM	_	Number=Sing	_	_	_	_
18	decrease	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	promoter	_	ADJ	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	globin	_	VERB	_	Number=Sing	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	retaining	_	VERB	_	VerbForm=Ger	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	region	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	alpha	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	globin	_	PROPN	_	Number=Sing	_	_	_	_
9	G	_	PROPN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_
11	C	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	rich	_	ADJ	_	Degree=Pos	_	_	_	_
14	5	_	NUM	_	NumType=Card	_	_	_	_
15	'	_	PUNCT	_	_	_	_	_	_
16	flanking	_	VERB	_	Number=Sing	_	_	_	_
17	region	_	NOUN	_	Number=Sing	_	_	_	_
18	augments	_	NOUN	_	Number=Plur	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	globin	_	VERB	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	chromatin	_	ADJ	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
29	manner	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	G	_	NOUN	_	Number=Sing	_	_	_	_
7	+	_	SYM	_	_	_	_	_	_
8	C	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	rich	_	ADJ	_	Degree=Pos	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	globin	_	ADJ	_	Degree=Pos	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	during	_	ADP	_	_	_	_	_	_
24	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
25	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	both	_	DET	_	_	_	_	_	_
7	footprint	_	NOUN	_	Number=Sing	_	_	_	_
8	analysis	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	functional	_	ADJ	_	Degree=Pos	_	_	_	_
11	assays	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	ability	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	G	_	NOUN	_	Number=Sing	_	_	_	_
18	+	_	SYM	_	_	_	_	_	_
19	C	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	rich	_	ADJ	_	Degree=Pos	_	_	_	_
22	region	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	globin	_	VERB	_	Degree=Pos	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	stably	_	ADV	_	_	_	_	_	_
33	integrated	_	VERB	_	Degree=Pos	_	_	_	_
34	alpha	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	globin	_	ADJ	_	Degree=Pos	_	_	_	_
37	gene	_	NOUN	_	Number=Sing	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
42	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
43	binding	_	NOUN	_	Number=Sing	_	_	_	_
44	sites	_	NOUN	_	Number=Plur	_	_	_	_
45	for	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	transcription	_	NOUN	_	Number=Sing	_	_	_	_
48	factor	_	NOUN	_	Number=Sing	_	_	_	_
49	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003608	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	central	_	ADJ	_	Degree=Pos	_	_	_	_
3	role	_	NOUN	_	Number=Sing	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	single	_	ADJ	_	Degree=Pos	_	_	_	_
7	c	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Myb	_	NOUN	_	Number=Sing	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
15	locus	_	NOUN	_	Number=Sing	_	_	_	_
16	control	_	NOUN	_	Number=Sing	_	_	_	_
17	region	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Locus	_	PROPN	_	Number=Sing	_	_	_	_
2	control	_	NOUN	_	Number=Sing	_	_	_	_
3	regions	_	NOUN	_	Number=Plur	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	LCRs	_	NOUN	_	Number=Plur	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	powerful	_	ADJ	_	Degree=Pos	_	_	_	_
9	assemblies	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cis	_	NOUN	_	Number=Sing	_	_	_	_
12	elements	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	organize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	actions	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	trans	_	NOUN	_	Number=Plur	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	acting	_	NOUN	_	Number=Sing	_	_	_	_
26	factors	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	2.3	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kb	_	NOUN	_	Number=Sing	_	_	_	_
5	LCR	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	adenosine	_	NOUN	_	Number=Sing	_	_	_	_
10	deaminase	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	ADA	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
16	intron	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	controls	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	200	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	bp	_	NOUN	_	Number=Sing	_	_	_	_
31	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
32	domain	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	extended	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	flanking	_	NOUN	_	VerbForm=Ger	_	_	_	_
36	sequences	_	NOUN	_	Number=Plur	_	_	_	_
37	that	_	PRON	_	PronType=Rel	_	_	_	_
38	facilitate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	from	_	ADP	_	_	_	_	_	_
41	within	_	ADP	_	_	_	_	_	_
42	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Prior	_	ADJ	_	Degree=Pos	_	_	_	_
2	analyses	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	28	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	bp	_	NOUN	_	Number=Sing	_	_	_	_
13	core	_	NOUN	_	Number=Sing	_	_	_	_
14	region	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	local	_	ADJ	_	Degree=Pos	_	_	_	_
17	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
18	augmentative	_	ADJ	_	Degree=Pos	_	_	_	_
19	cis	_	NOUN	_	Number=Sing	_	_	_	_
20	elements	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	core	_	NOUN	_	Number=Sing	_	_	_	_
7	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	single	_	ADJ	_	Degree=Pos	_	_	_	_
10	critical	_	ADJ	_	Degree=Pos	_	_	_	_
11	c	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	Myb	_	NOUN	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	both	_	DET	_	_	_	_	_	_
3	transiently	_	ADV	_	_	_	_	_	_
4	cotransfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	stable	_	ADJ	_	Degree=Pos	_	_	_	_
9	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	integrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	yeast	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_

1	c	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Myb	_	PROPN	_	Number=Sing	_	_	_	_
4	strongly	_	ADV	_	_	_	_	_	_
5	transactivated	_	VERB	_	Degree=Pos	_	_	_	_
6	reporter	_	NOUN	_	Number=Sing	_	_	_	_
7	constructs	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	polymerized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	core	_	NOUN	_	Number=Sing	_	_	_	_
12	sequences	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	c	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Myb	_	PROPN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	strongly	_	ADV	_	_	_	_	_	_
7	evident	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	lymphoblasts	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	active	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=1|Tense=Past|VerbForm=Fin	_	_	_	_
19	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	within	_	ADP	_	_	_	_	_	_
21	discrete	_	ADJ	_	Degree=Pos	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	structures	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Fetal	_	ADJ	_	Number=Sing	_	_	_	_
2	murine	_	NOUN	_	Number=Sing	_	_	_	_
3	thymus	_	NOUN	_	Number=Sing	_	_	_	_
4	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	striking	_	ADJ	_	Degree=Pos	_	_	_	_
7	concordance	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
10	c-myb	_	NOUN	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	mouse	_	NOUN	_	Number=Sing	_	_	_	_
16	ADA	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	ADA	_	NOUN	_	Number=Sing	_	_	_	_
20	LCR	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	transgene	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Point	_	NOUN	_	Number=Sing	_	_	_	_
2	mutation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	c-Myb	_	NOUN	_	Number=Sing	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	within	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	intact	_	NOUN	_	Number=Sing	_	_	_	_
10	2.3	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kb	_	NOUN	_	Number=Sing	_	_	_	_
13	LCR	_	NOUN	_	Number=Sing	_	_	_	_
14	severely	_	ADV	_	_	_	_	_	_
15	attenuated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	transfections	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	LCR	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
25	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Within	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	context	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	complex	_	ADJ	_	Degree=Pos	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	LCR	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	c	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	Myb	_	PROPN	_	Number=Sing	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	act	_	VERB	_	VerbForm=Inf	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	organizer	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	thymocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	via	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	single	_	ADJ	_	Degree=Pos	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	site	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003609	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	[	_	PUNCT	_	_	_	_	_	_
2	Hormonal	_	ADJ	_	Degree=Pos	_	_	_	_
3	metabolic	_	ADJ	_	Number=Sing	_	_	_	_
4	status	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	breast	_	NOUN	_	Number=Sing	_	_	_	_
7	cancer	_	NOUN	_	Number=Sing	_	_	_	_
8	patients	_	NOUN	_	Number=Plur	_	_	_	_
9	after	_	ADP	_	_	_	_	_	_
10	conservative	_	ADJ	_	Degree=Pos	_	_	_	_
11	surgery	_	NOUN	_	Number=Sing	_	_	_	_
12	:	_	PUNCT	_	_	_	_	_	_
13	comparison	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	prognostic	_	ADJ	_	Degree=Pos	_	_	_	_
17	criteria	_	NOUN	_	Number=Sing	_	_	_	_
18	]	_	PUNCT	_	_	_	_	_	_

1	Body	_	NOUN	_	Number=Sing	_	_	_	_
2	weight	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	body	_	NOUN	_	Number=Sing	_	_	_	_
5	mass	_	ADJ	_	Degree=Pos	_	_	_	_
6	index	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	body	_	NOUN	_	Number=Sing	_	_	_	_
9	fat	_	ADJ	_	Degree=Pos	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	lean	_	ADJ	_	Degree=Pos	_	_	_	_
12	body	_	NOUN	_	Number=Sing	_	_	_	_
13	mass	_	ADJ	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	blood	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	glucose	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	cholesterol	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	HDL	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	cholesterol	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	triglyceride	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	beta-lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	insulin	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	gonadotropin	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	estradiol	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	testosterone	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	SHBG	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	T3	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	T4	_	NOUN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	TSH	_	NOUN	_	Number=Sing	_	_	_	_
44	levels	_	NOUN	_	Number=Plur	_	_	_	_
45	as	_	ADV	_	_	_	_	_	_
46	well	_	ADV	_	Degree=Pos	_	_	_	_
47	as	_	ADP	_	_	_	_	_	_
48	estradiol	_	NOUN	_	Number=Sing	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
51	receptor	_	NOUN	_	Number=Sing	_	_	_	_
52	levels	_	NOUN	_	Number=Plur	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	excised	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
55	tumor	_	NOUN	_	Number=Sing	_	_	_	_
56	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
57	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
58	in	_	ADP	_	_	_	_	_	_
59	40	_	NUM	_	NumType=Card	_	_	_	_
60	patients	_	NOUN	_	Number=Plur	_	_	_	_
61	with	_	ADP	_	_	_	_	_	_
62	breast	_	NOUN	_	Number=Sing	_	_	_	_
63	cancer	_	NOUN	_	Number=Sing	_	_	_	_
64	prior	_	ADJ	_	Degree=Pos	_	_	_	_
65	to	_	ADP	_	_	_	_	_	_
66	conservative	_	ADJ	_	Degree=Pos	_	_	_	_
67	treatment	_	NOUN	_	Number=Sing	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	Said	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
2	anthropometric	_	ADJ	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	metabolic	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	hormonal	_	ADJ	_	Degree=Pos	_	_	_	_
7	parameters	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	index	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	tumor	_	NOUN	_	Number=Sing	_	_	_	_
18	selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	prognostic	_	ADJ	_	Degree=Pos	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	significant	_	ADJ	_	Degree=Pos	_	_	_	_
3	correlation	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	high	_	ADJ	_	Degree=Pos	_	_	_	_
6	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
7	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	2.5	_	NUM	_	NumType=Card	_	_	_	_
10	points	_	NOUN	_	Number=Plur	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	low	_	ADJ	_	Degree=Pos	_	_	_	_
14	body	_	NOUN	_	Number=Sing	_	_	_	_
15	mass	_	NOUN	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	fat	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Also	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	smoking	_	NOUN	_	Number=Sing	_	_	_	_
4	contributed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	loss	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	body	_	NOUN	_	Number=Sing	_	_	_	_
9	mass	_	NOUN	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	fat	_	NOUN	_	Number=Sing	_	_	_	_
12	;	_	PUNCT	_	_	_	_	_	_
13	however	_	ADV	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	rise	_	VERB	_	VerbForm=Inf	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Moderate	_	ADJ	_	Degree=Pos	_	_	_	_
2	body	_	NOUN	_	Number=Sing	_	_	_	_
3	mass	_	ADJ	_	Degree=Pos	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	relatively	_	ADV	_	_	_	_	_	_
6	low	_	ADJ	_	Degree=Pos	_	_	_	_
7	fat	_	ADJ	_	Degree=Pos	_	_	_	_
8	level	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	positive	_	ADJ	_	Degree=Pos	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	status	_	NOUN	_	Number=Sing	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	among	_	ADP	_	_	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	good	_	ADJ	_	Degree=Pos	_	_	_	_
18	prognosis	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	breast	_	NOUN	_	Number=Sing	_	_	_	_
21	cancer	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	early	_	ADJ	_	Degree=Pos	_	_	_	_
24	stages	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003610	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	FK506	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	ciclosporin	_	NOUN	_	Number=Sing	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	probes	_	NOUN	_	Number=Plur	_	_	_	_
7	for	_	SCONJ	_	_	_	_	_	_
8	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
9	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	transduction	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	immunosuppressants	_	NOUN	_	Number=Plur	_	_	_	_
3	ciclosporin	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	FK506	_	PROPN	_	Number=Sing	_	_	_	_
6	block	_	VERB	_	Number=Sing	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	Ca	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	+)-	_	SYM	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	signal	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	transduction	_	NOUN	_	Number=Sing	_	_	_	_
16	pathway	_	NOUN	_	Number=Sing	_	_	_	_
17	emanating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	thereby	_	ADV	_	_	_	_	_	_
26	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	helper	_	NOUN	_	Number=Sing	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	drugs	_	NOUN	_	Number=Plur	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	probes	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	chemists	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	biologists	_	NOUN	_	Number=Plur	_	_	_	_
10	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	uncovered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	several	_	ADJ	_	Degree=Pos	_	_	_	_
13	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
14	signalling	_	NOUN	_	Number=Sing	_	_	_	_
15	molecules	_	NOUN	_	Number=Plur	_	_	_	_
16	bridging	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	generation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	messenger	_	NOUN	_	Number=Sing	_	_	_	_
23	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
24	+	_	SYM	_	_	_	_	_	_
25	ions	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	among	_	ADP	_	_	_	_	_	_
36	which	_	PRON	_	PronType=Rel	_	_	_	_
37	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	calmodulin	_	ADJ	_	Degree=Pos	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
44	factor	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	T	_	NOUN	_	Number=Sing	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	NF	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	AT	_	NOUN	_	_	_	_	_	_
53	)	_	PUNCT	_	_	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Hence	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
4	+	_	SYM	_	_	_	_	_	_
5	binds	_	NOUN	_	Number=Plur	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	calmodulin	_	VERB	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	calmodulin	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
17	;	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	turn	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	may	_	AUX	_	VerbForm=Fin	_	_	_	_
26	dephosphorylate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
29	subunit	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	AT	_	NOUN	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
38	translocation	_	NOUN	_	Number=Sing	_	_	_	_
39	from	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
42	into	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
45	to	_	PART	_	_	_	_	_	_
46	form	_	VERB	_	VerbForm=Inf	_	_	_	_
47	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
48	competent	_	ADJ	_	Degree=Pos	_	_	_	_
49	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
50	activator	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	Jun	_	PROPN	_	Number=Sing	_	_	_	_
5	Liu	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	drugs	_	NOUN	_	Number=Plur	_	_	_	_
9	manifest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	effects	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	unprecedented	_	ADJ	_	Degree=Pos	_	_	_	_
15	fashion	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	directly	_	ADV	_	_	_	_	_	_
5	intercept	_	VERB	_	VerbForm=Inf	_	_	_	_
6	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	signalling	_	NOUN	_	Number=Sing	_	_	_	_
8	molecules	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Instead	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
4	form	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	tight	_	ADJ	_	Degree=Pos	_	_	_	_
6	complexes	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	different	_	ADJ	_	Degree=Pos	_	_	_	_
10	classes	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	abundant	_	ADJ	_	Degree=Pos	_	_	_	_
13	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
14	receptors	_	NOUN	_	Number=Plur	_	_	_	_
15	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	immunophilins	_	NOUN	_	Number=Plur	_	_	_	_
17	upon	_	SCONJ	_	_	_	_	_	_
18	entering	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	consequently	_	ADV	_	_	_	_	_	_
24	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	peptidyl	_	ADJ	_	Number=Sing	_	_	_	_
27	prolyl	_	NOUN	_	Number=Sing	_	_	_	_
28	cis	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	trans	_	NOUN	_	Number=Sing	_	_	_	_
31	isomerase	_	NOUN	_	Number=Sing	_	_	_	_
32	activities	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	structurally	_	ADV	_	_	_	_	_	_
4	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunophilin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	drug	_	NOUN	_	Number=Sing	_	_	_	_
8	complexes	_	NOUN	_	Number=Plur	_	_	_	_
9	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	inhibit	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003613	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Latent	_	ADJ	_	Degree=Pos	_	_	_	_
2	membrane	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	Barr	_	PROPN	_	Number=Sing	_	_	_	_
9	virus	_	NOUN	_	Number=Sing	_	_	_	_
10	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	JAK3	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	STAT	_	PROPN	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Latent	_	ADJ	_	Degree=Pos	_	_	_	_
2	membrane	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	like	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	permanently	_	ADV	_	_	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	tumor	_	NOUN	_	Number=Sing	_	_	_	_
17	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	TNF	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	absolutely	_	ADV	_	_	_	_	_	_
28	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	B	_	NOUN	_	Degree=Pos	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	Barr	_	PROPN	_	Number=Sing	_	_	_	_
37	virus	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
4	approaches	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
8	usurps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	signaling	_	NOUN	_	Number=Sing	_	_	_	_
11	pathways	_	NOUN	_	Number=Plur	_	_	_	_
12	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	AP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	via	_	ADP	_	_	_	_	_	_
25	two	_	NUM	_	NumType=Card	_	_	_	_
26	C	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	terminal	_	NOUN	_	Number=Sing	_	_	_	_
29	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
30	regions	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	third	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	encompassing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	proline	_	NOUN	_	Number=Sing	_	_	_	_
11	rich	_	ADJ	_	Degree=Pos	_	_	_	_
12	sequence	_	NOUN	_	Number=Sing	_	_	_	_
13	within	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	33	_	NUM	_	NumType=Card	_	_	_	_
16	bp	_	NOUN	_	Number=Sing	_	_	_	_
17	repetitive	_	ADJ	_	Degree=Pos	_	_	_	_
18	stretch	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
21	's	_	PART	_	_	_	_	_	_
22	C	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	terminus	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	Janus	_	PROPN	_	Number=Sing	_	_	_	_
32	kinase	_	NOUN	_	Number=Sing	_	_	_	_
33	3	_	NUM	_	NumType=Card	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	JAK3	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	interaction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	JAK3	_	PROPN	_	Number=Sing	_	_	_	_
7	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
12	auto	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	transphosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	JAK3	_	NOUN	_	Number=Sing	_	_	_	_
17	within	_	ADP	_	_	_	_	_	_
18	minutes	_	NOUN	_	Number=Plur	_	_	_	_
19	after	_	ADP	_	_	_	_	_	_
20	crosslinking	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	conditional	_	ADJ	_	Degree=Pos	_	_	_	_
24	NGF	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	R:LMP1	_	NOUN	_	Number=Sing	_	_	_	_
27	chimera	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	prerequisite	_	NOUN	_	Number=Sing	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	STAT	_	NOUN	_	Number=Sing	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	factors	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	novel	_	NOUN	_	Number=Sing	_	_	_	_
6	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
11	C	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	terminus	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	JAK	_	PROPN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	STAT	_	PROPN	_	Number=Sing	_	_	_	_
20	pathway	_	NOUN	_	Number=Sing	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	target	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	viral	_	ADJ	_	Degree=Pos	_	_	_	_
27	integral	_	ADJ	_	Degree=Pos	_	_	_	_
28	membrane	_	NOUN	_	Number=Sing	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	B	_	ADJ	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003614	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	patient	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	SCID	_	NOUN	_	Number=Sing	_	_	_	_
9	:	_	PUNCT	_	_	_	_	_	_
10	essential	_	ADJ	_	Degree=Pos	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
16	development	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Males	_	NOUN	_	Number=Plur	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	X	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	severe	_	ADJ	_	Degree=Pos	_	_	_	_
7	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	XSCID	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	defects	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	common	_	ADJ	_	Degree=Pos	_	_	_	_
17	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	gamma	_	NOUN	_	Number=Sing	_	_	_	_
20	chain	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	gamma	_	NOUN	_	Number=Sing	_	_	_	_
23	c	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	shared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	essential	_	ADJ	_	Degree=Pos	_	_	_	_
32	component	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	receptors	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	2	_	NUM	_	NumType=Card	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	IL	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	4	_	NUM	_	NumType=Card	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	IL	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	7	_	NUM	_	NumType=Card	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	IL	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	9	_	NUM	_	NumType=Card	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	and	_	CCONJ	_	_	_	_	_	_
59	IL	_	PROPN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	15	_	NUM	_	NumType=Card	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Janus	_	PROPN	_	Number=Sing	_	_	_	_
3	family	_	NOUN	_	Number=Sing	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	PROPN	_	Number=Sing	_	_	_	_
6	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	only	_	ADJ	_	Degree=Pos	_	_	_	_
10	signaling	_	NOUN	_	Degree=Pos	_	_	_	_
11	molecule	_	NOUN	_	Number=Sing	_	_	_	_
12	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	gamma	_	NOUN	_	Number=Sing	_	_	_	_
18	c	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	so	_	ADV	_	_	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	hypothesized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	defects	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
28	might	_	AUX	_	VerbForm=Fin	_	_	_	_
29	cause	_	VERB	_	VerbForm=Inf	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	XSCID	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	like	_	ADJ	_	Degree=Pos	_	_	_	_
34	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	girl	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	immunological	_	ADJ	_	Degree=Pos	_	_	_	_
5	features	_	NOUN	_	Number=Plur	_	_	_	_
6	indistinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	XSCID	_	PROPN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	therefore	_	ADV	_	_	_	_	_	_
13	selected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	analysis	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Barr	_	PROPN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	EBV	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	line	_	NOUN	_	Number=Sing	_	_	_	_
13	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	her	_	PRON	_	Gender=Fem|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	gamma	_	NOUN	_	Number=Sing	_	_	_	_
20	c	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	lacked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	greatly	_	ADV	_	_	_	_	_	_
29	diminished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
31	messenger	_	NOUN	_	Number=Sing	_	_	_	_
32	RNA	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Sequencing	_	PROPN	_	Number=Sing	_	_	_	_
2	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	different	_	ADJ	_	Degree=Pos	_	_	_	_
5	mutation	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	each	_	DET	_	_	_	_	_	_
8	allele	_	NOUN	_	Number=Sing	_	_	_	_
9	:	_	PUNCT	_	_	_	_	_	_

1	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	single	_	ADJ	_	Degree=Pos	_	_	_	_
3	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
4	insertion	_	NOUN	_	Number=Sing	_	_	_	_
5	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	frame	_	ADJ	_	Number=Sing	_	_	_	_
9	shift	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	premature	_	ADJ	_	Degree=Pos	_	_	_	_
12	termination	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
16	JH4	_	PROPN	_	Number=Sing	_	_	_	_
17	domain	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	nonsense	_	ADJ	_	Degree=Pos	_	_	_	_
21	mutation	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
25	JH2	_	PROPN	_	Number=Sing	_	_	_	_
26	domain	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	lack	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	signaling	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	as	_	SCONJ	_	_	_	_	_	_
14	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	inability	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
24	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	EBV	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	line	_	NOUN	_	Number=Sing	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	patient	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	functions	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	c	_	NOUN	_	Number=Sing	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	essential	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	lymphoid	_	NOUN	_	Degree=Pos	_	_	_	_
21	development	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	signaling	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003618	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Minimally	_	ADV	_	_	_	_	_	_
2	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	low	_	ADJ	_	Degree=Pos	_	_	_	_
4	density	_	NOUN	_	Number=Sing	_	_	_	_
5	lipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	responses	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	cyclic	_	ADJ	_	Degree=Pos	_	_	_	_
17	adenosine	_	ADJ	_	Degree=Pos	_	_	_	_
18	monophosphate	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	minimally	_	ADV	_	_	_	_	_	_
7	oxidized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	LDL	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	MM	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	LDL	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
19	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	interaction	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	not	_	ADV	_	_	_	_	_	_
25	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
28	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	not	_	ADV	_	_	_	_	_	_
31	neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
37	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
38	protein	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
43	colony	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
46	factor	_	NOUN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	M	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	CSF	_	NOUN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	signaling	_	NOUN	_	Number=Sing	_	_	_	_
10	pathways	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	M	_	NUM	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	CSF	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	MM	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	LDL	_	NOUN	_	Number=Sing	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	kinase	_	NOUN	_	Number=Sing	_	_	_	_
23	C	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	depleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	number	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
12	messenger	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	effects	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	MM	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	LDL	_	PROPN	_	Number=Sing	_	_	_	_
20	cited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	above	_	ADV	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Incubation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	MM	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	LDL	_	NOUN	_	Number=Sing	_	_	_	_
9	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	173	_	NUM	_	NumType=Card	_	_	_	_
12	%	_	SYM	_	Number=Sing	_	_	_	_
13	increase	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
16	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
17	levels	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Agents	_	NOUN	_	Number=Plur	_	_	_	_
2	which	_	PRON	_	PronType=Rel	_	_	_	_
3	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	including	_	VERB	_	VerbForm=Ger	_	_	_	_
8	cholera	_	NOUN	_	Number=Sing	_	_	_	_
9	toxin	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	pertussis	_	NOUN	_	Number=Sing	_	_	_	_
12	toxin	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	dibutyryl	_	ADJ	_	Degree=Pos	_	_	_	_
15	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	isoproterenol	_	NOUN	_	Number=Sing	_	_	_	_
19	mimicked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	actions	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	MM	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	LDL	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Agents	_	NOUN	_	Number=Plur	_	_	_	_
2	which	_	PRON	_	PronType=Rel	_	_	_	_
3	elevated	_	VERB	_	Degree=Pos	_	_	_	_
4	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	kappa	_	PROPN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	role	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
27	interactions	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
3	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
4	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
5	molecule	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	ELAM	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
10	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
11	can	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	kappa	_	PROPN	_	Number=Sing	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	ELAM	_	PROPN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	ELAM	_	PROPN	_	Number=Sing	_	_	_	_
25	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	only	_	ADV	_	_	_	_	_	_
28	slightly	_	ADV	_	_	_	_	_	_
29	elevated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	response	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	MM	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	LDL	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	present	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	evidence	_	NOUN	_	Number=Sing	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	LPS	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	actually	_	ADV	_	_	_	_	_	_
13	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	agents	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	_	_	_	_	_
17	elevated	_	VERB	_	Degree=Pos	_	_	_	_
18	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
19	levels	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003620	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	shared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	motifs	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	common	_	ADJ	_	Degree=Pos	_	_	_	_

1	Stat	_	PROPN	_	Number=Sing	_	_	_	_
2	proteins	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	generation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	pleiotropy	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	redundancy	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	4	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	7	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	13	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	15	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	bases	_	NOUN	_	Number=Plur	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	redundancy	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	pleiotropy	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	Stat	_	PROPN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
21	blood	_	NOUN	_	Number=Sing	_	_	_	_
22	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	PBLs	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	shared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
32	actions	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-2	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	rapidly	_	ADV	_	_	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	fresh	_	PROPN	_	Degree=Pos	_	_	_	_
12	PBL	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	preactivated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	PBL	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	7	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	15	_	NUM	_	NumType=Card	_	_	_	_
8	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	same	_	ADJ	_	Degree=Pos	_	_	_	_
11	complexes	_	NOUN	_	Number=Plur	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	feature	_	NOUN	_	Number=Sing	_	_	_	_
19	explained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	existence	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	similar	_	ADJ	_	Degree=Pos	_	_	_	_
25	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	motifs	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
32	domains	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2R	_	PROPN	_	Number=Sing	_	_	_	_
37	beta	_	PROPN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	7R	_	PROPN	_	Number=Sing	_	_	_	_
42	that	_	PRON	_	PronType=Rel	_	_	_	_
43	can	_	AUX	_	VerbForm=Fin	_	_	_	_
44	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
45	as	_	ADP	_	_	_	_	_	_
46	docking	_	NOUN	_	Number=Sing	_	_	_	_
47	sites	_	NOUN	_	Number=Plur	_	_	_	_
48	for	_	ADP	_	_	_	_	_	_
49	Stat	_	PROPN	_	Number=Sing	_	_	_	_
50	proteins	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	13	_	NUM	_	NumType=Card	_	_	_	_
4	Induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	same	_	ADJ	_	Degree=Pos	_	_	_	_
7	complexes	_	NOUN	_	Number=Plur	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	finding	_	NOUN	_	Number=Sing	_	_	_	_
15	explained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
18	studies	_	NOUN	_	Number=Plur	_	_	_	_
19	implicating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	4R	_	NOUN	_	Number=Sing	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	shared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	component	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	receptors	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	single	_	ADJ	_	Degree=Pos	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	different	_	ADJ	_	Degree=Pos	_	_	_	_
11	combinations	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Stat	_	PROPN	_	Number=Sing	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	under	_	ADP	_	_	_	_	_	_
16	different	_	ADJ	_	Degree=Pos	_	_	_	_
17	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
18	conditions	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	also	_	ADV	_	_	_	_	_	_
22	indicate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	two	_	NUM	_	NumType=Card	_	_	_	_
24	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	which	_	DET	_	PronType=Int	_	_	_	_
27	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
28	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
29	can	_	AUX	_	VerbForm=Fin	_	_	_	_
30	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	same	_	ADJ	_	Degree=Pos	_	_	_	_
33	Stat	_	PROPN	_	Number=Sing	_	_	_	_
34	protein	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003622	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	essential	_	ADJ	_	Degree=Pos	_	_	_	_
4	GATA	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	Ets	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	motifs	_	NOUN	_	Number=Plur	_	_	_	_
9	within	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	platelet	_	PROPN	_	Number=Sing	_	_	_	_
15	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
16	Ib	_	PROPN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Platelet	_	PROPN	_	Number=Sing	_	_	_	_
2	glycoprotein	_	PROPN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	GP	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	Ib	_	X	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	IX	_	PROPN	_	Number=Sing	_	_	_	_
9	-V	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	multisubunit	_	ADJ	_	Degree=Pos	_	_	_	_
13	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	supports	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	platelet	_	NOUN	_	Number=Sing	_	_	_	_
18	attachment	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	thrombogenic	_	ADJ	_	Degree=Pos	_	_	_	_
21	surfaces	_	NOUN	_	Number=Plur	_	_	_	_
22	at	_	ADP	_	_	_	_	_	_
23	sites	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
26	injury	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	congenital	_	ADJ	_	Degree=Pos	_	_	_	_
3	absence	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	results	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	bleeding	_	VERB	_	VerbForm=Ger	_	_	_	_
11	disorder	_	NOUN	_	Number=Sing	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	"	_	PUNCT	_	_	_	_	_	_
15	giant	_	ADJ	_	Degree=Pos	_	_	_	_
16	"	_	PUNCT	_	_	_	_	_	_
17	platelets	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	condition	_	NOUN	_	Number=Sing	_	_	_	_
21	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	complex	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	platelet	_	VERB	_	Number=Sing	_	_	_	_
29	morphogenesis	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
3	better	_	ADV	_	Degree=Cmp	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	GP	_	NOUN	_	Number=Sing	_	_	_	_
9	Ib	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	IX	_	NOUN	_	Number=Sing	_	_	_	_
12	-V	_	NOUN	_	Number=Sing	_	_	_	_
13	complex	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	studies	_	NOUN	_	Number=Plur	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	undertaken	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	define	_	VERB	_	VerbForm=Inf	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	essential	_	ADJ	_	Degree=Pos	_	_	_	_
22	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
23	elements	_	NOUN	_	Number=Plur	_	_	_	_
24	supporting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	subunit	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	complex	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	GP	_	PROPN	_	Number=Sing	_	_	_	_
37	Ib	_	NOUN	_	Number=Sing	_	_	_	_
38	alpha	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	GP	_	PROPN	_	Number=Sing	_	_	_	_

1	Ib	_	PROPN	_	Number=Sing	_	_	_	_
2	alpha	_	NOUN	_	Number=Sing	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	transfection	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	erythroleukemia	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	reporter	_	NOUN	_	Number=Sing	_	_	_	_
15	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
16	coding	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	initiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	fragment	_	NOUN	_	Number=Sing	_	_	_	_
7	extending	_	VERB	_	VerbForm=Ger	_	_	_	_
8	2,738	_	NUM	_	NumType=Card	_	_	_	_
9	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
10	5'	_	NUM	_	Number=Plur	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	start	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	identification	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	253	_	NUM	_	NumType=Card	_	_	_	_
23	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
24	retaining	_	VERB	_	VerbForm=Ger	_	_	_	_
25	full	_	ADJ	_	Degree=Pos	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	erythroleukemia	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	nonhematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
5	lineage	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	endothelial	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	GP	_	NOUN	_	Number=Sing	_	_	_	_
15	Ib	_	NOUN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	no	_	ADV	_	_	_	_	_	_
21	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
22	than	_	ADP	_	_	_	_	_	_
23	background	_	NOUN	_	Number=Sing	_	_	_	_
24	levels	_	NOUN	_	Number=Plur	_	_	_	_
25	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	promoterless	_	ADJ	_	Degree=Pos	_	_	_	_
28	constructs	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	shift	_	NOUN	_	Number=Sing	_	_	_	_
3	assays	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
9	studies	_	NOUN	_	Number=Plur	_	_	_	_
10	defined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	essential	_	ADJ	_	Degree=Pos	_	_	_	_
12	GATA	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	Ets	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	motifs	_	NOUN	_	Number=Plur	_	_	_	_
17	93	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	150	_	NUM	_	NumType=Card	_	_	_	_
20	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
21	upstream	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	start	_	NOUN	_	Number=Sing	_	_	_	_
26	site	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	finding	_	NOUN	_	Number=Sing	_	_	_	_
30	which	_	PRON	_	PronType=Rel	_	_	_	_
31	further	_	ADV	_	Degree=Pos	_	_	_	_
32	substantiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
34	elements	_	NOUN	_	Number=Plur	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	important	_	ADJ	_	Degree=Pos	_	_	_	_
37	determinants	_	NOUN	_	Number=Plur	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	define	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	essential	_	ADJ	_	Degree=Pos	_	_	_	_
5	cis	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
8	elements	_	NOUN	_	Number=Plur	_	_	_	_
9	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	GP	_	NOUN	_	Number=Sing	_	_	_	_
15	Ib	_	NOUN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
19	insights	_	NOUN	_	Number=Plur	_	_	_	_
20	into	_	ADP	_	_	_	_	_	_
21	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
22	events	_	NOUN	_	Number=Plur	_	_	_	_
23	coinciding	_	VERB	_	VerbForm=Ger	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	release	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	normal	_	ADJ	_	Degree=Pos	_	_	_	_
29	platelets	_	NOUN	_	Number=Plur	_	_	_	_
30	into	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	bloodstream	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003623	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	lipopolysaccharide	_	NOUN	_	Degree=Pos	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	interleukin	_	ADJ	_	Number=Sing	_	_	_	_
13	1beta	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	NFkappaB	_	ADJ	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	but	_	CCONJ	_	_	_	_	_	_
19	not	_	ADV	_	_	_	_	_	_
20	NFkappaB	_	ADJ	_	Number=Sing	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	translocation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	1beta	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	production	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	steady	_	ADJ	_	Degree=Pos	_	_	_	_
11	state	_	NOUN	_	Number=Sing	_	_	_	_
12	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
13	levels	_	NOUN	_	Number=Plur	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	predominantly	_	ADV	_	_	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	result	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
31	1beta	_	NOUN	_	Number=Sing	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	interleukin	_	ADJ	_	Number=Sing	_	_	_	_
4	1beta	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	such	_	ADJ	_	Degree=Pos	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
12	6	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	tumor	_	NOUN	_	Number=Sing	_	_	_	_
15	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
21	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	recent	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	translocation	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
22	sought	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
25	whether	_	SCONJ	_	_	_	_	_	_
26	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
27	translocated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	absence	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	tyrosine	_	ADJ	_	Number=Sing	_	_	_	_
33	kinase	_	NOUN	_	Number=Sing	_	_	_	_
34	activity	_	NOUN	_	Number=Sing	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	active	_	ADJ	_	Degree=Pos	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	stimulating	_	VERB	_	VerbForm=Ger	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	pro-monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	THP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	interleukin	_	ADJ	_	Number=Sing	_	_	_	_
24	1beta	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
29	kinase	_	NOUN	_	Number=Sing	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
2	kinases	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	translocation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	absence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	ability	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	impaired	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
9	;	_	PUNCT	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	absence	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	while	_	SCONJ	_	_	_	_	_	_
7	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	mediators	_	NOUN	_	Number=Plur	_	_	_	_
14	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	tyrosine	_	ADJ	_	Degree=Pos	_	_	_	_
16	kinase	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	obligatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	lipopolysaccharide	_	NOUN	_	Degree=Pos	_	_	_	_
27	signal	_	NOUN	_	Number=Sing	_	_	_	_
28	transduction	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003626	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cleavage	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	SP1	_	PROPN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	caspases	_	NOUN	_	Number=Plur	_	_	_	_
8	during	_	ADP	_	_	_	_	_	_
9	anti-IgM	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Apoptosis	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	instrumental	_	ADJ	_	Degree=Pos	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	processes	_	NOUN	_	Number=Plur	_	_	_	_
7	generating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	diversity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	repertoire	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Autoreactive	_	ADJ	_	Number=Sing	_	_	_	_
2	B	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	eliminated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	anti-IgM	_	ADJ	_	Degree=Pos	_	_	_	_
9	crosslinking	_	NOUN	_	Number=Sing	_	_	_	_
10	after	_	SCONJ	_	_	_	_	_	_
11	encountering	_	VERB	_	VerbForm=Ger	_	_	_	_
12	self	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	antigens	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	precise	_	ADJ	_	Degree=Pos	_	_	_	_
18	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
19	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	still	_	ADV	_	_	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	well	_	ADV	_	Degree=Pos	_	_	_	_
29	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	SP1	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	Burkitt	_	NOUN	_	Number=Sing	_	_	_	_
15	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	line	_	NOUN	_	Number=Sing	_	_	_	_
18	BL60	_	NOUN	_	Number=Sing	_	_	_	_
19	during	_	ADP	_	_	_	_	_	_
20	anti-IgM	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
7	products	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	approximately	_	ADV	_	_	_	_	_	_
10	68	_	NUM	_	NumType=Card	_	_	_	_
11	kDa	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	45	_	NUM	_	NumType=Card	_	_	_	_
14	kDa	_	NOUN	_	Number=Sing	_	_	_	_
15	after	_	ADP	_	_	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Cleavage	_	NOUN	_	Number=Sing	_	_	_	_
2	could	_	AUX	_	VerbForm=Fin	_	_	_	_
3	be	_	AUX	_	VerbForm=Inf	_	_	_	_
4	completely	_	ADV	_	_	_	_	_	_
5	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	zDEVD	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	fmk	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	caspase	_	NOUN	_	Number=Sing	_	_	_	_
16	3	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	like	_	ADJ	_	Degree=Pos	_	_	_	_
19	proteases	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	vitro	_	NOUN	_	Number=Sing	_	_	_	_
4	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
7	SP1	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	recombinant	_	ADJ	_	Number=Sing	_	_	_	_
10	caspase	_	NOUN	_	Number=Sing	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	CPP32	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	caspase	_	NOUN	_	Number=Sing	_	_	_	_
17	7	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	Mch	_	NOUN	_	Number=Sing	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	results	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	similar	_	ADJ	_	Degree=Pos	_	_	_	_
25	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
26	products	_	NOUN	_	Number=Plur	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
29	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	vivo	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Recombinant	_	ADJ	_	Number=Sing	_	_	_	_
2	caspase	_	NOUN	_	Number=Sing	_	_	_	_
3	6	_	NUM	_	NumType=Card	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	Mch	_	NOUN	_	Number=Sing	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	primarily	_	ADV	_	_	_	_	_	_
9	generates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	68	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kDa	_	NOUN	_	Number=Sing	_	_	_	_
14	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
15	product	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	as	_	SCONJ	_	_	_	_	_	_
18	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	after	_	ADP	_	_	_	_	_	_
20	calcium	_	NOUN	_	Number=Sing	_	_	_	_
21	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	CaI	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	caspase	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	ICE	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	cleave	_	VERB	_	VerbForm=Inf	_	_	_	_
12	SP1	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vitro	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	time	_	NOUN	_	Number=Sing	_	_	_	_
3	course	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	SP1	_	NOUN	_	Number=Sing	_	_	_	_
6	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
7	during	_	ADP	_	_	_	_	_	_
8	anti-IgM	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	paralleled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	increase	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	caspase	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	DEVD	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	p-nitroanilide	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	DEVD	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	pNA	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	band	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	decrease	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	intensity	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	full	_	ADJ	_	Degree=Pos	_	_	_	_
15	length	_	NOUN	_	Number=Sing	_	_	_	_
16	SP1	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	DNA	_	NOUN	_	Number=Sing	_	_	_	_
19	complex	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	increase	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	intensity	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	smaller	_	ADJ	_	Degree=Cmp	_	_	_	_
29	complex	_	NOUN	_	Number=Sing	_	_	_	_
30	due	_	ADP	_	_	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	binding	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	one	_	NUM	_	NumType=Card	_	_	_	_
36	SP1	_	NOUN	_	Number=Sing	_	_	_	_
37	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
38	product	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	Edman	_	PROPN	_	Number=Sing	_	_	_	_
3	sequencing	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	could	_	AUX	_	VerbForm=Fin	_	_	_	_
6	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	caspase	_	NOUN	_	Number=Sing	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	Asp584	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	D584AQPQAGR	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	generating	_	VERB	_	VerbForm=Ger	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	22	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kDa	_	NOUN	_	Number=Sing	_	_	_	_
23	C	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	terminal	_	NOUN	_	Number=Sing	_	_	_	_
26	SP1	_	NOUN	_	Number=Sing	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	fragment	_	NOUN	_	Number=Sing	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	still	_	ADV	_	_	_	_	_	_
31	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	DNA	_	PROPN	_	Number=Sing	_	_	_	_
34	binding	_	NOUN	_	Number=Sing	_	_	_	_
35	site	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	SP1	_	PROPN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vivo	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	vitro	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	underlining	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	central	_	ADJ	_	Degree=Pos	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	caspase	_	NOUN	_	Number=Sing	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	like	_	ADJ	_	Degree=Pos	_	_	_	_
27	proteases	_	NOUN	_	Number=Plur	_	_	_	_
28	during	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	process	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	anti-IgM	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003640	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	[	_	PUNCT	_	_	_	_	_	_
2	Effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	regimen	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	kidney	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	tonifying	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	qi	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	invigorating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	aging	_	VERB	_	VerbForm=Ger	_	_	_	_
16	changes	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	]	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	plasma	_	NOUN	_	Number=Sing	_	_	_	_
3	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
4	concentration	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	GCR	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	32	_	NUM	_	NumType=Card	_	_	_	_
22	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
23	aged	_	ADJ	_	Degree=Pos	_	_	_	_
24	persons	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	13	_	NUM	_	NumType=Card	_	_	_	_
27	young	_	ADJ	_	Degree=Pos	_	_	_	_
28	adults	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	animal	_	NOUN	_	Number=Sing	_	_	_	_
3	experiment	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	GCR	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	spleen	_	NOUN	_	Number=Sing	_	_	_	_
8	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	18	_	NUM	_	NumType=Card	_	_	_	_
15	aged	_	ADJ	_	Degree=Pos	_	_	_	_
16	rats	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	9	_	NUM	_	NumType=Card	_	_	_	_
19	young	_	ADJ	_	Degree=Pos	_	_	_	_
20	rats	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	GCR	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	significantly	_	ADV	_	_	_	_	_	_
8	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	aged	_	ADJ	_	Degree=Pos	_	_	_	_
12	persons	_	NOUN	_	Number=Plur	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	rats	_	NOUN	_	Number=Plur	_	_	_	_
15	than	_	ADP	_	_	_	_	_	_
16	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	young	_	ADJ	_	Degree=Pos	_	_	_	_
20	while	_	SCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	plasma	_	NOUN	_	Number=Sing	_	_	_	_
23	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
24	level	_	NOUN	_	Number=Sing	_	_	_	_
25	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	n't	_	PART	_	_	_	_	_	_
27	change	_	VERB	_	VerbForm=Inf	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	aging	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	So	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	think	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	GCR	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	more	_	ADV	_	_	_	_	_	_
8	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
9	than	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	plasma	_	NOUN	_	Number=Sing	_	_	_	_
12	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
13	level	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	reflect	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	aging	_	VERB	_	VerbForm=Ger	_	_	_	_
18	change	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	adrenal	_	ADJ	_	Degree=Pos	_	_	_	_
22	cortex	_	NOUN	_	Number=Sing	_	_	_	_
23	function	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	treatment	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	regimen	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Kidney	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	tonifying	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Qi	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	invigorating	_	VERB	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	GCR	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	aged	_	ADJ	_	Degree=Pos	_	_	_	_
21	persons	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	rats	_	NOUN	_	Number=Plur	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	way	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	function	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	aged	_	ADJ	_	Degree=Pos	_	_	_	_
37	adrenal	_	ADJ	_	Degree=Pos	_	_	_	_
38	cortex	_	NOUN	_	Number=Sing	_	_	_	_
39	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
40	improved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003645	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Immune	_	ADJ	_	Degree=Pos	_	_	_	_
2	functions	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
5	parameters	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	hormone	_	NOUN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	status	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	breast	_	NOUN	_	Number=Sing	_	_	_	_
12	cancer	_	NOUN	_	Number=Sing	_	_	_	_
13	patients	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	carried	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	out	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	detailed	_	ADJ	_	Degree=Pos	_	_	_	_
7	analysis	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	immune	_	ADJ	_	Number=Sing	_	_	_	_
12	functions	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	breast	_	NOUN	_	Number=Sing	_	_	_	_
15	cancer	_	NOUN	_	Number=Sing	_	_	_	_
16	patients	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	comparison	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
21	controls	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	possible	_	ADJ	_	Degree=Pos	_	_	_	_
3	correlation	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	immune	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
8	parameters	_	NOUN	_	Number=Plur	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	analysed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	50	_	NUM	_	NumType=Card	_	_	_	_
13	breast	_	NOUN	_	Number=Sing	_	_	_	_
14	cancer	_	NOUN	_	Number=Sing	_	_	_	_
15	patients	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Immune	_	ADJ	_	Degree=Pos	_	_	_	_
2	parameters	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	natural	_	ADJ	_	Degree=Pos	_	_	_	_
5	killer	_	NOUN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	functions	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	numbers	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	analysed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	against	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
23	parameters	_	NOUN	_	Number=Plur	_	_	_	_
24	comprising	_	VERB	_	VerbForm=Ger	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	tumour	_	NOUN	_	Number=Sing	_	_	_	_
27	burden	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	stage	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	disease	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	hormone	_	NOUN	_	Number=Sing	_	_	_	_
39	receptors	_	NOUN	_	Number=Plur	_	_	_	_
40	on	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	tumour	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	analyse	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	immune	_	ADJ	_	Degree=Pos	_	_	_	_
7	function	_	NOUN	_	Number=Sing	_	_	_	_
8	data	_	NOUN	_	Number=Sing	_	_	_	_
9	effectively	_	ADV	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	low	_	ADJ	_	Degree=Pos	_	_	_	_
12	responders	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	stringent	_	ADJ	_	Degree=Pos	_	_	_	_
17	cut	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	off	_	NOUN	_	Degree=Pos	_	_	_	_
20	values	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Considerably	_	ADV	_	_	_	_	_	_
2	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
3	proportions	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	low	_	ADJ	_	Degree=Pos	_	_	_	_
6	responders	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	among	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	patient	_	ADJ	_	Number=Sing	_	_	_	_
12	population	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	numbers	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	CD3	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	cytolysis	_	NOUN	_	Number=Sing	_	_	_	_
12	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	oestrogen	_	ADJ	_	Number=Sing	_	_	_	_
18	receptors	_	NOUN	_	Number=Plur	_	_	_	_
19	independently	_	ADV	_	_	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	histological	_	ADJ	_	Degree=Pos	_	_	_	_
25	parameters	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003647	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Charybdotoxin-sensitive	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Ca	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	+)-	_	SYM	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	membrane	_	NOUN	_	Number=Sing	_	_	_	_
9	potential	_	ADJ	_	Degree=Pos	_	_	_	_
10	changes	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	involved	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	B	_	NOUN	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	involvement	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	ion	_	NOUN	_	Number=Sing	_	_	_	_
5	channels	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	B	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	supported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	many	_	ADJ	_	Degree=Pos	_	_	_	_
16	reports	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	changes	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	ion	_	NOUN	_	Number=Sing	_	_	_	_
21	fluxes	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	membrane	_	NOUN	_	Number=Sing	_	_	_	_
24	potential	_	NOUN	_	Number=Sing	_	_	_	_
25	after	_	ADP	_	_	_	_	_	_
26	mitogen	_	PROPN	_	Number=Sing	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	B	_	PROPN	_	Degree=Pos	_	_	_	_
5	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	early	_	ADJ	_	Degree=Pos	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	transient	_	ADJ	_	Degree=Pos	_	_	_	_
11	hyperpolarization	_	NOUN	_	Number=Sing	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	ligand	_	NOUN	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Inasmuch	_	ADV	_	Degree=Pos	_	_	_	_
2	as	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	change	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	membrane	_	NOUN	_	Number=Sing	_	_	_	_
7	potential	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	elevation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	free	_	ADJ	_	Degree=Pos	_	_	_	_
14	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
15	calcium	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	hyperpolarization	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	presumably	_	ADV	_	_	_	_	_	_
21	through	_	ADP	_	_	_	_	_	_
22	opening	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	Ca	_	PROPN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	+	_	SYM	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	K+	_	NOUN	_	Number=Sing	_	_	_	_
32	channels	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	charybdotoxin	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	known	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Ca	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	+)-	_	SYM	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	K	_	NUM	_	Number=Sing	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_
17	channels	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	study	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
25	channels	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	lymphocyte	_	ADJ	_	Degree=Pos	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	mitogenesis	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	charybdotoxin	_	NOUN	_	Number=Sing	_	_	_	_
5	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	ligand	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	transient	_	ADJ	_	Degree=Pos	_	_	_	_
11	membrane	_	NOUN	_	Number=Sing	_	_	_	_
12	hyperpolarization	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	B	_	ADJ	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	dose	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	fashion	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	without	_	SCONJ	_	_	_	_	_	_
26	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
27	changes	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
30	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
31	+	_	SYM	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	blockade	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	Ca	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	K	_	PROPN	_	Number=Sing	_	_	_	_
14	+	_	CCONJ	_	_	_	_	_	_
15	channel	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	changes	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	cycle	_	NOUN	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	production	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2R	_	NUM	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	T	_	NOUN	_	Number=Sing	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	mitogenesis	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	imply	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	membrane	_	ADJ	_	Number=Sing	_	_	_	_
6	potential	_	ADJ	_	Degree=Pos	_	_	_	_
7	changes	_	NOUN	_	Number=Plur	_	_	_	_
8	secondary	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	ligand	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	opening	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	Ca	_	PROPN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	K+	_	NOUN	_	Number=Sing	_	_	_	_
24	channels	_	NOUN	_	Number=Plur	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	involved	_	ADJ	_	Degree=Pos	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	B	_	ADJ	_	Degree=Pos	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	T	_	PROPN	_	Number=Sing	_	_	_	_
32	lymphocyte	_	NOUN	_	Degree=Pos	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	mitogenesis	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003650	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Barr	_	PROPN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	antigen	_	NOUN	_	Number=Sing	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	latent	_	ADJ	_	Degree=Pos	_	_	_	_
10	membrane	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	independently	_	ADV	_	_	_	_	_	_
13	transactivate	_	VERB	_	Degree=Pos	_	_	_	_
14	p53	_	NOUN	_	Number=Sing	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	B-cell	_	PROPN	_	Number=Sing	_	_	_	_
2	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	Barr	_	PROPN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	EBV	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	permanent	_	ADJ	_	Degree=Pos	_	_	_	_
15	control	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
19	processes	_	NOUN	_	Number=Plur	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	normally	_	ADV	_	_	_	_	_	_
22	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	division	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	functions	_	NOUN	_	Number=Plur	_	_	_	_
29	possessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	p53	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	number	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	normal	_	ADJ	_	Degree=Pos	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	types	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	evaluate	_	VERB	_	VerbForm=Inf	_	_	_	_
6	relationships	_	NOUN	_	Number=Plur	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	EBV	_	PROPN	_	Number=Sing	_	_	_	_
9	latent	_	ADJ	_	Degree=Pos	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	p53	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	p53	_	NOUN	_	Number=Sing	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
20	approximately	_	ADV	_	_	_	_	_	_
21	10	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	5	_	NUM	_	NumType=Card	_	_	_	_
27	days	_	NOUN	_	Number=Plur	_	_	_	_
28	after	_	ADP	_	_	_	_	_	_
29	EBV	_	PROPN	_	Number=Sing	_	_	_	_
30	infection	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	SCONJ	_	_	_	_	_	_
32	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
34	human	_	ADJ	_	Degree=Pos	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	;	_	PUNCT	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	p53	_	NOUN	_	Number=Sing	_	_	_	_
41	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
42	transcriptionally	_	ADV	_	_	_	_	_	_
43	active	_	ADJ	_	Degree=Pos	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Latent	_	ADJ	_	Degree=Pos	_	_	_	_
2	membrane	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	lesser	_	ADJ	_	Degree=Cmp	_	_	_	_
10	extent	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	EBV	_	PROPN	_	Number=Sing	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	antigen	_	NOUN	_	Number=Sing	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	mediated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	increase	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	p53	_	NOUN	_	Number=Sing	_	_	_	_
21	levels	_	NOUN	_	Number=Plur	_	_	_	_
22	via	_	ADP	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003651	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Grf40	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	Grb2	_	PROPN	_	Number=Sing	_	_	_	_
6	family	_	NOUN	_	Number=Sing	_	_	_	_
7	member	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	involved	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	interaction	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	SLP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	76	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	LAT	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	molecularly	_	ADV	_	_	_	_	_	_
3	cloned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	new	_	ADJ	_	Degree=Pos	_	_	_	_
6	Grb2	_	PROPN	_	Number=Sing	_	_	_	_
7	family	_	NOUN	_	Number=Sing	_	_	_	_
8	member	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	named	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	Grf40	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	common	_	ADJ	_	Degree=Pos	_	_	_	_
16	SH3	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	SH2	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	SH3	_	NOUN	_	Number=Sing	_	_	_	_
21	motif	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Grf40	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	predominant	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	particularly	_	ADV	_	_	_	_	_	_
11	T	_	ADJ	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Grf40	_	PROPN	_	Number=Sing	_	_	_	_
2	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	SH2	_	NOUN	_	Number=Sing	_	_	_	_
6	domain	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	76	_	NUM	_	NumType=Card	_	_	_	_
13	kD	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	SLP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	SYM	_	_	_	_	_	_
17	76	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	via	_	ADP	_	_	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	SH3	_	NOUN	_	Number=Sing	_	_	_	_
22	domain	_	NOUN	_	Number=Sing	_	_	_	_
23	more	_	ADV	_	_	_	_	_	_
24	tightly	_	ADV	_	_	_	_	_	_
25	than	_	ADP	_	_	_	_	_	_
26	Grb2	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Incidentally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Grf40	_	PROPN	_	Number=Sing	_	_	_	_
4	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	linker	_	VERB	_	VerbForm=Inf	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	LAT	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	possibly	_	ADV	_	_	_	_	_	_
16	via	_	ADP	_	_	_	_	_	_
17	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	SH2	_	NOUN	_	Number=Sing	_	_	_	_
19	domain	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	wild	_	ADJ	_	Degree=Pos	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	Grf40	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	significant	_	ADJ	_	Degree=Pos	_	_	_	_
13	increase	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	SLP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	76	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	AT	_	NOUN	_	_	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	upon	_	ADP	_	_	_	_	_	_
41	T	_	PROPN	_	Number=Sing	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	receptor	_	NOUN	_	Number=Sing	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	TCR	_	NOUN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	whereas	_	SCONJ	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	COOH	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	terminal	_	NOUN	_	Number=Sing	_	_	_	_

1	SH3	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	Grf40	_	PROPN	_	Number=Sing	_	_	_	_
5	mutant	_	NOUN	_	Number=Sing	_	_	_	_
6	lacked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	any	_	DET	_	_	_	_	_	_
8	recognizable	_	ADJ	_	Degree=Pos	_	_	_	_
9	increase	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	SH2	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	Grf40	_	PROPN	_	Number=Sing	_	_	_	_
8	mutant	_	NOUN	_	Number=Sing	_	_	_	_
9	led	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
16	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	activities	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	effect	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Int	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	apparently	_	ADV	_	_	_	_	_	_
25	stronger	_	ADJ	_	Degree=Cmp	_	_	_	_
26	than	_	ADP	_	_	_	_	_	_
27	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	SH2	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	Grb2	_	PROPN	_	Number=Sing	_	_	_	_
34	mutant	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Grf40	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	adaptor	_	NOUN	_	Number=Sing	_	_	_	_
9	molecule	_	NOUN	_	Number=Sing	_	_	_	_
10	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	TCR	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	VERB	_	Degree=Pos	_	_	_	_
15	signaling	_	VERB	_	Number=Sing	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	more	_	ADV	_	_	_	_	_	_
19	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
20	interaction	_	NOUN	_	Number=Sing	_	_	_	_
21	than	_	ADP	_	_	_	_	_	_
22	Grb2	_	PROPN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	SLP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	76	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	LAT	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003655	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	largely	_	ADV	_	_	_	_	_	_
8	due	_	ADP	_	_	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	immunologically	_	ADV	_	_	_	_	_	_
14	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	such	_	ADJ	_	Degree=Pos	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	_	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	GR	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	humans	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
5	splicing	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	GR	_	PROPN	_	Number=Sing	_	_	_	_
9	precursor	_	NOUN	_	Number=Sing	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	gives	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	rise	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	two	_	NUM	_	NumType=Card	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	GRalpha	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	GRbeta	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	GRbeta	_	PROPN	_	Number=Sing	_	_	_	_
6	could	_	AUX	_	VerbForm=Fin	_	_	_	_
7	antagonize	_	VERB	_	VerbForm=Inf	_	_	_	_
8	GRalpha	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	VERB	_	Degree=Pos	_	_	_	_
11	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
17	element	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	GRE	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	reporter	_	NOUN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	COS	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	7	_	NUM	_	NumType=Card	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	designed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	roles	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	two	_	NUM	_	NumType=Card	_	_	_	_
13	GR	_	NOUN	_	Number=Sing	_	_	_	_
14	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
19	transrepression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	recently	_	ADV	_	_	_	_	_	_
4	developed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	transfection	_	NOUN	_	Number=Sing	_	_	_	_
6	technique	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	primary	_	ADJ	_	Degree=Pos	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	548	_	NUM	_	NumType=Card	_	_	_	_
20	bp	_	PROPN	_	Number=Sing	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
27	reporter	_	NOUN	_	Number=Sing	_	_	_	_
28	construct	_	VERB	_	Number=Sing	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
31	ester	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	calcium	_	NOUN	_	Number=Sing	_	_	_	_
34	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
35	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	reversed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	similar	_	ADJ	_	Degree=Pos	_	_	_	_
42	extent	_	NOUN	_	Number=Sing	_	_	_	_
43	as	_	ADP	_	_	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
46	T	_	PROPN	_	Number=Sing	_	_	_	_
47	lymphoma	_	PROPN	_	Number=Sing	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	with	_	ADP	_	_	_	_	_	_
51	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
52	GRalpha	_	PROPN	_	Number=Sing	_	_	_	_
53	expression	_	NOUN	_	Number=Sing	_	_	_	_
54	vector	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Transfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	GRbeta	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	vector	_	NOUN	_	Number=Sing	_	_	_	_
7	alone	_	ADV	_	_	_	_	_	_
8	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	result	_	VERB	_	VerbForm=Inf	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	repression	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	GRbeta	_	PROPN	_	Number=Sing	_	_	_	_
4	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	antagonize	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	repressive	_	ADJ	_	Degree=Pos	_	_	_	_
9	effects	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	GRalpha	_	PROPN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Surprisingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	GRbeta	_	PROPN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	cause	_	VERB	_	VerbForm=Inf	_	_	_	_
12	significant	_	ADJ	_	Degree=Pos	_	_	_	_
13	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	GRalpha	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	GRE	_	NUM	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
24	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
25	reporter	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	either	_	ADV	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	transrepressive	_	ADJ	_	Degree=Pos	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	glucocorticoids	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	exclusively	_	ADV	_	_	_	_	_	_
17	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	GRalpha	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	GRbeta	_	PROPN	_	Number=Sing	_	_	_	_
2	can	_	AUX	_	VerbForm=Fin	_	_	_	_
3	neither	_	CCONJ	_	_	_	_	_	_
4	antagonize	_	VERB	_	VerbForm=Inf	_	_	_	_
5	GRalpha	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
8	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
9	nor	_	CCONJ	_	_	_	_	_	_
10	transrepression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	pattern	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	GRbeta	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	antiglucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003662	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	HLA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	DR	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	CD33	_	PROPN	_	Number=Sing	_	_	_	_
7	+	_	SYM	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	CD56	_	PROPN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	CD16	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	natural	_	ADJ	_	Degree=Pos	_	_	_	_
17	killer	_	NOUN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	acute	_	NOUN	_	Number=Sing	_	_	_	_
20	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
21	:	_	PUNCT	_	_	_	_	_	_

1	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	unrecognized	_	ADJ	_	Degree=Pos	_	_	_	_
4	form	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	acute	_	ADJ	_	Degree=Pos	_	_	_	_
7	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
8	potentially	_	ADV	_	_	_	_	_	_
9	misdiagnosed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	French	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	American	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	British	_	ADJ	_	Degree=Pos	_	_	_	_
16	acute	_	NOUN	_	Number=Sing	_	_	_	_
17	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
18	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	M3	_	NOUN	_	Number=Sing	_	_	_	_
21	[	_	PUNCT	_	_	_	_	_	_
22	see	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
23	comments	_	NOUN	_	Number=Plur	_	_	_	_
24	]	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	previously	_	ADV	_	_	_	_	_	_
8	unrecognized	_	ADJ	_	Degree=Pos	_	_	_	_
9	form	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	acute	_	ADJ	_	Degree=Pos	_	_	_	_
12	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	shares	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	features	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	natural	_	ADJ	_	Degree=Pos	_	_	_	_
21	killer	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	NK	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	From	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	consecutive	_	ADJ	_	Degree=Pos	_	_	_	_
4	series	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	350	_	NUM	_	NumType=Card	_	_	_	_
7	cases	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	adult	_	NOUN	_	Number=Sing	_	_	_	_
10	de	_	NOUN	_	Number=Sing	_	_	_	_
11	novo	_	NOUN	_	Number=Sing	_	_	_	_
12	acute	_	VERB	_	Degree=Pos	_	_	_	_
13	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
14	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	AML	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	20	_	NUM	_	NumType=Card	_	_	_	_
22	cases	_	NOUN	_	Number=Plur	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	6	_	NUM	_	NumType=Card	_	_	_	_
25	%	_	SYM	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	unique	_	ADJ	_	Degree=Pos	_	_	_	_
30	immunophenotype	_	NOUN	_	Number=Sing	_	_	_	_
31	:	_	PUNCT	_	_	_	_	_	_
32	CD33	_	NOUN	_	Number=Sing	_	_	_	_
33	+	_	SYM	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	CD56	_	NOUN	_	Number=Sing	_	_	_	_
36	+	_	SYM	_	_	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	CD11a	_	PROPN	_	Number=Sing	_	_	_	_
39	+	_	SYM	_	_	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	CD13lo	_	PROPN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	CD15lo	_	PROPN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	CD34+/-,	_	PROPN	_	Number=Sing	_	_	_	_

1	HLA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	DR	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	CD16	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Multicolor	_	PROPN	_	Number=Sing	_	_	_	_
2	flow	_	NOUN	_	Number=Sing	_	_	_	_
3	cytometric	_	PROPN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	confirmed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	coexpression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	CD33	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	CD13	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	CD15	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	NK	_	PROPN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	CD56	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	antigens	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	each	_	DET	_	_	_	_	_	_
28	case	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	whereas	_	SCONJ	_	_	_	_	_	_
31	reverse	_	NOUN	_	Number=Sing	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
34	chain	_	NOUN	_	Number=Sing	_	_	_	_
35	reaction	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	RT	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	PCR	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	assays	_	NOUN	_	Number=Plur	_	_	_	_
42	confirmed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	identity	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	CD56	_	NOUN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	neural	_	ADJ	_	Degree=Pos	_	_	_	_
49	cell	_	NOUN	_	Number=Sing	_	_	_	_
50	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
51	molecule	_	NOUN	_	Number=Sing	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
55	blasts	_	NOUN	_	Number=Plur	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	cases	_	NOUN	_	Number=Plur	_	_	_	_
4	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	CD4	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	no	_	DET	_	_	_	_	_	_
8	case	_	NOUN	_	Number=Sing	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	CD2	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	CD3	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	CD8	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	no	_	DET	_	_	_	_	_	_
18	case	_	NOUN	_	Number=Sing	_	_	_	_
19	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
21	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	TCR	_	NOUN	_	Number=Sing	_	_	_	_
30	beta	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	gamma	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	delta	_	PROPN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Leukemic	_	ADJ	_	Number=Sing	_	_	_	_
2	blasts	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	majority	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cases	_	NOUN	_	Number=Plur	_	_	_	_
8	shared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	unique	_	ADJ	_	Degree=Pos	_	_	_	_
10	morphologic	_	ADJ	_	Degree=Pos	_	_	_	_
11	features	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	deeply	_	ADV	_	_	_	_	_	_
14	invaginated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	membranes	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	scant	_	ADJ	_	Degree=Pos	_	_	_	_
19	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	fine	_	ADJ	_	Degree=Pos	_	_	_	_
22	azurophilic	_	ADJ	_	Degree=Pos	_	_	_	_
23	granularity	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	finely	_	ADV	_	_	_	_	_	_
27	granular	_	ADJ	_	Degree=Pos	_	_	_	_
28	Sudan	_	PROPN	_	Number=Sing	_	_	_	_
29	black	_	ADJ	_	Degree=Pos	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	myeloperoxidase	_	NOUN	_	Number=Sing	_	_	_	_
33	cytochemical	_	ADJ	_	Degree=Pos	_	_	_	_
34	reactivity	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	that	_	PRON	_	PronType=Rel	_	_	_	_
37	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	remarkably	_	ADV	_	_	_	_	_	_
39	similar	_	ADJ	_	Degree=Pos	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	acute	_	ADJ	_	Degree=Pos	_	_	_	_
44	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
45	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	APL	_	NOUN	_	Number=Sing	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	;	_	PUNCT	_	_	_	_	_	_
50	particularly	_	ADV	_	_	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	microgranular	_	ADJ	_	Degree=Pos	_	_	_	_
53	variant	_	NOUN	_	Number=Sing	_	_	_	_
54	(	_	PUNCT	_	_	_	_	_	_
55	FAB	_	ADJ	_	Number=Sing	_	_	_	_
56	AML	_	NOUN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	M3v	_	NOUN	_	Number=Sing	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	all	_	DET	_	_	_	_	_	_
4	20	_	NUM	_	NumType=Card	_	_	_	_
5	cases	_	NOUN	_	Number=Plur	_	_	_	_
6	lacked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	t	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	15	_	NUM	_	NumType=Card	_	_	_	_
11	;	_	PUNCT	_	_	_	_	_	_
12	17	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	17	_	NUM	_	NumType=Card	_	_	_	_
16	cases	_	NOUN	_	Number=Plur	_	_	_	_
17	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	lacked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	retinoic	_	ADJ	_	Number=Sing	_	_	_	_
23	acid	_	NOUN	_	Number=Sing	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	RAR	_	PROPN	_	Number=Sing	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	fusion	_	NOUN	_	Number=Sing	_	_	_	_
31	transcript	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	RT	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	PCR	_	NOUN	_	Number=Sing	_	_	_	_
36	assays	_	NOUN	_	Number=Plur	_	_	_	_
37	;	_	PUNCT	_	_	_	_	_	_
38	12	_	NUM	_	NumType=Card	_	_	_	_
39	cases	_	NOUN	_	Number=Plur	_	_	_	_
40	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	46	_	NUM	_	NumType=Card	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	XX	_	NOUN	_	Number=Sing	_	_	_	_
44	or	_	CCONJ	_	_	_	_	_	_
45	46,XY	_	NUM	_	NumType=Card	_	_	_	_
46	karyotypes	_	NOUN	_	Number=Plur	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	whereas	_	SCONJ	_	_	_	_	_	_
49	2	_	NUM	_	NumType=Card	_	_	_	_
50	cases	_	NOUN	_	Number=Plur	_	_	_	_
51	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
52	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
53	of	_	ADP	_	_	_	_	_	_
54	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
55	17q	_	NOUN	_	Number=Sing	_	_	_	_
56	:	_	PUNCT	_	_	_	_	_	_
57	1	_	NUM	_	NumType=Card	_	_	_	_
58	with	_	ADP	_	_	_	_	_	_
59	del	_	NOUN	_	Number=Sing	_	_	_	_
60	(	_	PUNCT	_	_	_	_	_	_
61	17	_	NUM	_	NumType=Card	_	_	_	_
62	)	_	PUNCT	_	_	_	_	_	_
63	(	_	PUNCT	_	_	_	_	_	_
64	q25	_	NUM	_	NumType=Card	_	_	_	_
65	)	_	PUNCT	_	_	_	_	_	_
66	and	_	CCONJ	_	_	_	_	_	_
67	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
68	other	_	ADJ	_	Degree=Pos	_	_	_	_
69	with	_	ADP	_	_	_	_	_	_
70	t	_	NOUN	_	Number=Sing	_	_	_	_
71	(	_	PUNCT	_	_	_	_	_	_
72	11	_	NUM	_	NumType=Card	_	_	_	_
73	;	_	PUNCT	_	_	_	_	_	_
74	17	_	NUM	_	NumType=Card	_	_	_	_
75	)	_	PUNCT	_	_	_	_	_	_
76	(	_	PUNCT	_	_	_	_	_	_
77	q23;q21	_	NUM	_	NumType=Card	_	_	_	_
78	)	_	PUNCT	_	_	_	_	_	_
79	and	_	CCONJ	_	_	_	_	_	_
80	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
81	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
82	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
83	zinc	_	NOUN	_	Number=Sing	_	_	_	_
84	finger	_	NOUN	_	Number=Sing	_	_	_	_
85	/	_	PUNCT	_	_	_	_	_	_
86	RAR	_	PROPN	_	Number=Sing	_	_	_	_
87	alpha	_	NOUN	_	Number=Sing	_	_	_	_
88	fusion	_	NOUN	_	Number=Sing	_	_	_	_
89	transcript	_	NOUN	_	Number=Sing	_	_	_	_
90	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	cases	_	NOUN	_	Number=Plur	_	_	_	_
3	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	6/20	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	including	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	case	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	t	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	11	_	NUM	_	NumType=Card	_	_	_	_
15	;	_	PUNCT	_	_	_	_	_	_
16	17	_	NUM	_	NumType=Card	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	vitro	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	response	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	all	_	DET	_	_	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	trans	_	NOUN	_	Number=Sing	_	_	_	_
30	retinoic	_	PROPN	_	Degree=Pos	_	_	_	_
31	acid	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
37	that	_	SCONJ	_	_	_	_	_	_
38	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
39	cases	_	NOUN	_	Number=Plur	_	_	_	_
40	may	_	AUX	_	VerbForm=Fin	_	_	_	_
41	account	_	VERB	_	VerbForm=Inf	_	_	_	_
42	for	_	ADP	_	_	_	_	_	_
43	some	_	DET	_	_	_	_	_	_
44	APLs	_	NOUN	_	Number=Plur	_	_	_	_
45	that	_	PRON	_	PronType=Rel	_	_	_	_
46	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
47	not	_	PART	_	_	_	_	_	_
48	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
50	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
51	response	_	NOUN	_	Number=Sing	_	_	_	_
52	to	_	ADP	_	_	_	_	_	_
53	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Four	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	6	_	NUM	_	NumType=Card	_	_	_	_
4	cases	_	NOUN	_	Number=Plur	_	_	_	_
5	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	functional	_	ADJ	_	Degree=Pos	_	_	_	_
8	NK	_	PROPN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
12	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	relationship	_	NOUN	_	Number=Sing	_	_	_	_
17	between	_	ADP	_	_	_	_	_	_
18	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
19	unique	_	ADJ	_	Degree=Pos	_	_	_	_
20	CD33	_	NOUN	_	Number=Sing	_	_	_	_
21	+	_	SYM	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	CD56	_	PROPN	_	Number=Sing	_	_	_	_
24	+	_	SYM	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	CD16	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	acute	_	ADJ	_	Degree=Pos	_	_	_	_
29	leukemias	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	normal	_	ADJ	_	Degree=Pos	_	_	_	_
32	CD56	_	NOUN	_	Number=Sing	_	_	_	_
33	+	_	SYM	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	CD16	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	NK	_	PROPN	_	Number=Sing	_	_	_	_
38	precursor	_	NOUN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	combination	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	panning	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	multiparameter	_	NOUN	_	Degree=Pos	_	_	_	_
8	flow	_	NOUN	_	Number=Sing	_	_	_	_
9	cytometric	_	ADJ	_	Degree=Pos	_	_	_	_
10	sorting	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	normal	_	ADJ	_	Degree=Pos	_	_	_	_
16	CD56	_	NOUN	_	Number=Sing	_	_	_	_
17	+	_	SYM	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	CD33	_	PROPN	_	Number=Sing	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	CD16	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	counterpart	_	NOUN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	at	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	frequency	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	%	_	SYM	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	%	_	SYM	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
38	blood	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
41	individuals	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	form	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	acute	_	ADJ	_	Degree=Pos	_	_	_	_
9	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	arise	_	VERB	_	VerbForm=Inf	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	transformation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	precursor	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	common	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	NK	_	PROPN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	lineages	_	NOUN	_	Number=Plur	_	_	_	_
27	;	_	PUNCT	_	_	_	_	_	_
28	thus	_	ADV	_	_	_	_	_	_
29	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
30	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	designation	_	NOUN	_	Number=Sing	_	_	_	_
33	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	NK	_	PROPN	_	Number=Sing	_	_	_	_
36	acute	_	NOUN	_	Degree=Pos	_	_	_	_
37	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Recognition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	new	_	ADJ	_	Degree=Pos	_	_	_	_
5	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
6	entity	_	NOUN	_	Number=Sing	_	_	_	_
7	will	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	SCONJ	_	_	_	_	_	_
11	distinguishing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	nonresponsive	_	ADJ	_	Degree=Pos	_	_	_	_
16	cases	_	NOUN	_	Number=Plur	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
21	true	_	ADJ	_	Degree=Pos	_	_	_	_
22	APL	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003667	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Single	_	ADJ	_	Degree=Pos	_	_	_	_
2	point	_	NOUN	_	Number=Sing	_	_	_	_
3	estimation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
6	receptors	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	normal	_	ADJ	_	Degree=Pos	_	_	_	_
11	subjects	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	children	_	NOUN	_	Number=Plur	_	_	_	_
15	under	_	ADP	_	_	_	_	_	_
16	long	_	ADJ	_	Degree=Pos	_	_	_	_
17	term	_	NOUN	_	Number=Sing	_	_	_	_
18	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	single	_	ADJ	_	Degree=Pos	_	_	_	_
3	point	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
7	receptors	_	NOUN	_	Number=Plur	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	GR	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	measurement	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	developed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	common	_	ADJ	_	Degree=Pos	_	_	_	_
30	multi-point	_	ADJ	_	Number=Sing	_	_	_	_
31	Scatchard	_	ADJ	_	Number=Sing	_	_	_	_
32	analysis	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	assay	_	NOUN	_	Number=Sing	_	_	_	_
3	conditions	_	NOUN	_	Number=Plur	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	concentration	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	ligand	_	NOUN	_	Number=Sing	_	_	_	_
9	20	_	NUM	_	NumType=Card	_	_	_	_
10	nmol	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	l	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	incubation	_	NOUN	_	Number=Sing	_	_	_	_
15	time	_	NOUN	_	Number=Sing	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	h	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	count	_	NOUN	_	Number=Sing	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	6	_	NUM	_	NumType=Card	_	_	_	_
25	mil	_	NOUN	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	cells	_	NOUN	_	Number=Plur	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	tube	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	assay	_	NOUN	_	Number=Sing	_	_	_	_
7	volume	_	NOUN	_	Number=Sing	_	_	_	_
8	0.25	_	NUM	_	NumType=Card	_	_	_	_
9	ml	_	NOUN	_	Number=Sing	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	attempt	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	undertaken	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	use	_	VERB	_	VerbForm=Inf	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	harvester	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	separation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	unbound	_	ADJ	_	Degree=Pos	_	_	_	_
18	ligand	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Though	_	SCONJ	_	_	_	_	_	_
2	specifically	_	ADV	_	_	_	_	_	_
3	bound	_	ADJ	_	Degree=Pos	_	_	_	_
4	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
5	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	whole	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	assay	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	using	_	VERB	_	VerbForm=Ger	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	harvester	_	NOUN	_	Number=Sing	_	_	_	_
16	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	well	_	ADV	_	Degree=Pos	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	almost	_	ADV	_	_	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	one	_	NUM	_	NumType=Card	_	_	_	_
22	order	_	NOUN	_	Number=Sing	_	_	_	_
23	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
24	values	_	NOUN	_	Number=Plur	_	_	_	_
25	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	latter	_	ADJ	_	Degree=Pos	_	_	_	_
29	method	_	NOUN	_	Number=Sing	_	_	_	_
30	render	_	VERB	_	VerbForm=Inf	_	_	_	_
31	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
32	non-applicable	_	ADJ	_	Degree=Pos	_	_	_	_
33	for	_	ADP	_	_	_	_	_	_
34	receptor	_	NOUN	_	Number=Sing	_	_	_	_
35	quantitation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	9	_	NUM	_	NumType=Card	_	_	_	_
5	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
6	volunteers	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	average	_	ADJ	_	Degree=Pos	_	_	_	_
9	GR	_	NOUN	_	Number=Sing	_	_	_	_
10	concentration	_	NOUN	_	Number=Sing	_	_	_	_
11	7131	_	NUM	_	NumType=Card	_	_	_	_
12	+/-	_	SYM	_	_	_	_	_	_
13	1256	_	NUM	_	NumType=Card	_	_	_	_
14	sites	_	NOUN	_	Number=Plur	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	excellently	_	ADV	_	_	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
22	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	Scatchard	_	PROPN	_	Number=Sing	_	_	_	_
26	analysis	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	single	_	ADJ	_	Degree=Pos	_	_	_	_
3	point	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	applied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	determination	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	GH	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	10	_	NUM	_	NumType=Card	_	_	_	_
15	children	_	NOUN	_	Number=Plur	_	_	_	_
16	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	large	_	ADJ	_	Degree=Pos	_	_	_	_
19	doses	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	prednisone	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	average	_	ADJ	_	Degree=Pos	_	_	_	_
3	values	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
6	volunteers	_	NOUN	_	Number=Plur	_	_	_	_
7	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	differ	_	VERB	_	VerbForm=Inf	_	_	_	_
10	significantly	_	ADV	_	_	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
13	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
16	children	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	though	_	SCONJ	_	_	_	_	_	_
19	much	_	ADJ	_	Degree=Pos	_	_	_	_
20	broader	_	ADJ	_	Degree=Cmp	_	_	_	_
21	range	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	patients	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003670	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	2	_	NUM	_	NumType=Card	_	_	_	_
3	signaling	_	NOUN	_	Number=Sing	_	_	_	_
4	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Stat	_	PROPN	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	most	_	ADV	_	_	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
7	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	immune	_	ADJ	_	Degree=Pos	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	potent	_	ADJ	_	Degree=Pos	_	_	_	_
23	activator	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	function	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	T	_	NOUN	_	Number=Sing	_	_	_	_
31	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	natural	_	ADJ	_	Degree=Pos	_	_	_	_
34	killer	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	propagated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	within	_	ADP	_	_	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	recently	_	ADV	_	_	_	_	_	_
13	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	two	_	NUM	_	NumType=Card	_	_	_	_
21	kinases	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	Jak	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	Jak	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	3	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
32	steps	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
36	pathway	_	NOUN	_	Number=Sing	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
40	that	_	PRON	_	PronType=Rel	_	_	_	_
41	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
42	to	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	activation	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	specific	_	ADJ	_	Degree=Pos	_	_	_	_
47	genes	_	NOUN	_	Number=Plur	_	_	_	_
48	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
49	not	_	PART	_	_	_	_	_	_
50	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
51	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	many	_	ADJ	_	Degree=Pos	_	_	_	_
3	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	Jak	_	PROPN	_	Number=Sing	_	_	_	_
7	kinases	_	NOUN	_	Number=Plur	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
13	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	members	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	Stat	_	PROPN	_	Number=Sing	_	_	_	_
21	family	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factors	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	ability	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	trigger	_	VERB	_	VerbForm=Inf	_	_	_	_
34	Stat	_	PROPN	_	Number=Sing	_	_	_	_
35	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
36	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
37	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Exposure	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	natural	_	ADJ	_	Degree=Pos	_	_	_	_
11	killer	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	line	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	NKL	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	leads	_	NOUN	_	Number=Plur	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
27	alpha	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
30	beta	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	as	_	ADV	_	_	_	_	_	_
36	well	_	ADV	_	Degree=Pos	_	_	_	_
37	as	_	ADP	_	_	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	two	_	NUM	_	NumType=Card	_	_	_	_
40	Stat	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	related	_	ADJ	_	Degree=Pos	_	_	_	_
43	proteins	_	NOUN	_	Number=Plur	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	p94	_	NOUN	_	Number=Sing	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	p95	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	p94	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	p95	_	NUM	_	Number=Sing	_	_	_	_
4	share	_	NOUN	_	Number=Sing	_	_	_	_
5	homology	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
8	at	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	Src	_	PROPN	_	Number=Sing	_	_	_	_
16	homology	_	NOUN	_	Number=Sing	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	SH2	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	domain	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	otherwise	_	ADV	_	_	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	immunologically	_	ADV	_	_	_	_	_	_
27	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	Stat	_	NOUN	_	Number=Sing	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	translocate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	DNA	_	NOUN	_	Number=Sing	_	_	_	_
18	sequence	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	involved	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	immune	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	function	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003671	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	90	_	NUM	_	NumType=Card	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	double	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	RNA	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	substrate	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	double	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	RNA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	PKR	_	PROPN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	NFAT	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	central	_	ADJ	_	Degree=Pos	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	initiating	_	VERB	_	VerbForm=Ger	_	_	_	_
10	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	through	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	early	_	ADJ	_	Degree=Pos	_	_	_	_
19	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	including	_	VERB	_	VerbForm=Ger	_	_	_	_
23	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	NFAT	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
14	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	antigen	_	NOUN	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	element	_	NOUN	_	Number=Sing	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	ARRE	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Multiple	_	ADJ	_	Degree=Pos	_	_	_	_
2	proteins	_	NOUN	_	Number=Plur	_	_	_	_
3	exhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
4	ARRE	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	including	_	VERB	_	VerbForm=Ger	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	extracts	_	NOUN	_	Number=Plur	_	_	_	_
21	consisting	_	VERB	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	Mr	_	PROPN	_	Number=Sing	_	_	_	_
24	=	_	PUNCT	_	_	_	_	_	_
25	90	_	NUM	_	NumType=Card	_	_	_	_
26	000	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	NF90	_	NUM	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	Mr	_	NOUN	_	Number=Sing	_	_	_	_
32	=	_	PUNCT	_	_	_	_	_	_
33	45	_	NUM	_	NumType=Card	_	_	_	_
34	000	_	NUM	_	NumType=Card	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	NF45	_	NUM	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	subunits	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	subunits	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	NF90	_	PROPN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	encode	_	VERB	_	VerbForm=Inf	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	two	_	NUM	_	NumType=Card	_	_	_	_
20	domains	_	NOUN	_	Number=Plur	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	predicted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	form	_	VERB	_	VerbForm=Inf	_	_	_	_
26	motifs	_	NOUN	_	Number=Plur	_	_	_	_
27	capable	_	ADJ	_	Degree=Pos	_	_	_	_
28	of	_	SCONJ	_	_	_	_	_	_
29	binding	_	VERB	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	double	_	ADJ	_	Degree=Pos	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	RNA	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	vitro	_	NOUN	_	Number=Sing	_	_	_	_
4	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	polypeptides	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	NF90	_	PROPN	_	Number=Sing	_	_	_	_
12	specifically	_	ADV	_	_	_	_	_	_
13	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	double	_	ADJ	_	Degree=Pos	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	RNA	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	NF90	_	PROPN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	double	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	RNA	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	manner	_	NOUN	_	Number=Sing	_	_	_	_
15	likely	_	ADV	_	Degree=Pos	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	interferon	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	double	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	RNA	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	kinase	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	PKR	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NF90	_	PROPN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	not	_	ADV	_	_	_	_	_	_
10	only	_	ADV	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	T-cells	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	nonimmune	_	ADJ	_	Degree=Pos	_	_	_	_
18	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	almost	_	ADV	_	_	_	_	_	_
9	exclusively	_	ADV	_	_	_	_	_	_
10	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	ribosome	_	ADJ	_	Number=Sing	_	_	_	_
14	salt	_	NOUN	_	Number=Sing	_	_	_	_
15	wash	_	NOUN	_	Number=Sing	_	_	_	_
16	fraction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lysates	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003674	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Prolactin	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	receptors	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	signal	_	VERB	_	Number=Sing	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	MGF	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	like	_	ADP	_	Degree=Pos	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	surface	_	NOUN	_	Number=Sing	_	_	_	_
4	receptors	_	NOUN	_	Number=Plur	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	PRL	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	_	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	structurally	_	ADV	_	_	_	_	_	_
18	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	share	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	tasks	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	T	_	PROPN	_	Number=Sing	_	_	_	_
26	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	can	_	AUX	_	VerbForm=Fin	_	_	_	_
3	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
4	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	over	_	ADV	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	lapping	_	VERB	_	VerbForm=Ger	_	_	_	_
12	sets	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	PRL	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	both	_	ADV	_	_	_	_	_	_
10	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	Jak	_	PROPN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	Stat	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	signal	_	NOUN	_	Number=Sing	_	_	_	_
18	transducer	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	activator	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	pathway	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	ability	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	PRL	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	Stat	_	PROPN	_	Number=Sing	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	different	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	DNA	_	NOUN	_	Number=Sing	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	specificities	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	reactivities	_	NOUN	_	Number=Plur	_	_	_	_
8	toward	_	ADP	_	_	_	_	_	_
9	Stat	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	antisera	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	mol	_	NOUN	_	Number=Sing	_	_	_	_
17	wt	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	PRL	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	DNA	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	binding	_	VERB	_	Number=Sing	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	Nb2	_	PROPN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	C196	_	NUM	_	NumType=Card	_	_	_	_
35	T	_	NOUN	_	Number=Sing	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	lines	_	NOUN	_	Number=Plur	_	_	_	_
38	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
39	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	comparison	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	Stat	_	PROPN	_	Number=Sing	_	_	_	_
6	proteins	_	NOUN	_	Number=Plur	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	interferon	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	PRL	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	6	_	NUM	_	NumType=Card	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	T47D	_	PROPN	_	Number=Sing	_	_	_	_
21	mammary	_	ADJ	_	Degree=Pos	_	_	_	_
22	tumor	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	made	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	parameters	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	indistinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	one	_	NUM	_	NumType=Card	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	PRL	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	factors	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	closely	_	ADV	_	_	_	_	_	_
5	related	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	mammary	_	ADJ	_	Degree=Pos	_	_	_	_
8	gland	_	NOUN	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	rapidly	_	ADV	_	_	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	upon	_	ADP	_	_	_	_	_	_
16	interaction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	PRL	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	respective	_	ADJ	_	Degree=Pos	_	_	_	_
26	receptors	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	related	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	also	_	ADV	_	_	_	_	_	_
11	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	emphasize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	PRL	_	NOUN	_	Number=Sing	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	regulator	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	immune	_	ADJ	_	Degree=Pos	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	Stat	_	PROPN	_	Number=Sing	_	_	_	_
20	factors	_	NOUN	_	Number=Plur	_	_	_	_
21	mammary	_	ADJ	_	Degree=Pos	_	_	_	_
22	gland	_	NOUN	_	Degree=Pos	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
28	play	_	VERB	_	VerbForm=Inf	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	role	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	regulation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	during	_	ADP	_	_	_	_	_	_
38	T	_	NOUN	_	Number=Sing	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	development	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003682	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	Pit	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	children	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
13	hormone	_	NOUN	_	Number=Sing	_	_	_	_
14	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Pit	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	transactivates	_	VERB	_	Degree=Pos	_	_	_	_
16	promoters	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	growth	_	NOUN	_	Number=Sing	_	_	_	_
19	hormone	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	prolactin	_	NOUN	_	Degree=Pos	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	three	_	NUM	_	NumType=Card	_	_	_	_
3	unrelated	_	ADJ	_	Degree=Pos	_	_	_	_
4	Japanese	_	ADJ	_	Degree=Pos	_	_	_	_
5	children	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
9	hormone	_	NOUN	_	Number=Sing	_	_	_	_
10	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	three	_	NUM	_	NumType=Card	_	_	_	_
15	point	_	NOUN	_	Number=Sing	_	_	_	_
16	mutations	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	Pit	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	Pro24Leu	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	Arg143Gln	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	Arg271Trp	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	on	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	major	_	ADJ	_	Degree=Pos	_	_	_	_
35	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
36	region	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	POU	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	specific	_	ADJ	_	Degree=Pos	_	_	_	_
41	domain	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	POU	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	homeodomain	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	respectively	_	ADV	_	_	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003691	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	HIV	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	LEF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	HMG	_	PROPN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	nucleosome	_	ADJ	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	assembled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	DNA	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	vitro	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Lymphoid	_	PROPN	_	Number=Sing	_	_	_	_
2	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	LEF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	high	_	ADJ	_	Degree=Pos	_	_	_	_
16	mobility	_	NOUN	_	Number=Sing	_	_	_	_
17	group	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	HMG	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	TCR	_	NOUN	_	Number=Sing	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	context	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	restricted	_	VERB	_	Degree=Pos	_	_	_	_
39	manner	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	T	_	PROPN	_	Number=Sing	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	paper	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	distal	_	ADJ	_	Degree=Pos	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	DNA	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	binding	_	VERB	_	Number=Sing	_	_	_	_
29	sites	_	NOUN	_	Number=Plur	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	LEF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	Ets	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	also	_	ADV	_	_	_	_	_	_
40	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	functional	_	ADJ	_	Degree=Pos	_	_	_	_
43	context	_	NOUN	_	Number=Sing	_	_	_	_
44	for	_	ADP	_	_	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	by	_	ADP	_	_	_	_	_	_
47	LEF	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	1	_	NUM	_	NumType=Card	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	First	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	mutations	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	LEF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	multimerized	_	VERB	_	Degree=Pos	_	_	_	_
20	copies	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	HIV	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
29	T	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	that	_	SCONJ	_	_	_	_	_	_
34	LEF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1/GAL4	_	NOUN	_	Number=Sing	_	_	_	_
37	can	_	AUX	_	VerbForm=Fin	_	_	_	_
38	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	GAL4	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	substituted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	HIV	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
47	80	_	NUM	_	NumType=Card	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	to	_	ADP	_	_	_	_	_	_
50	100	_	NUM	_	NumType=Card	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	fold	_	NOUN	_	Number=Sing	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	vivo	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Second	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	recombinant	_	PROPN	_	Number=Sing	_	_	_	_
4	LEF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	assembled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	DNA	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	vitro	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	nucleosome	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	assembly	_	NOUN	_	Number=Sing	_	_	_	_
7	system	_	NOUN	_	Number=Sing	_	_	_	_
8	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	Drosophila	_	PROPN	_	Number=Sing	_	_	_	_
11	embryos	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	packaging	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	DNA	_	NOUN	_	Number=Sing	_	_	_	_
20	into	_	ADP	_	_	_	_	_	_
21	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	vitro	_	NOUN	_	Number=Sing	_	_	_	_
24	strongly	_	ADV	_	_	_	_	_	_
25	represses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	HIV	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	repression	_	NOUN	_	Number=Sing	_	_	_	_
33	can	_	AUX	_	VerbForm=Fin	_	_	_	_
34	be	_	AUX	_	VerbForm=Inf	_	_	_	_
35	counteracted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	efficiently	_	ADV	_	_	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	preincubation	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	DNA	_	NOUN	_	Number=Sing	_	_	_	_
42	with	_	ADP	_	_	_	_	_	_
43	LEF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	or	_	CCONJ	_	_	_	_	_	_
48	LEF	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	1	_	NUM	_	NumType=Card	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	Ets	_	NOUN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	1	_	X	_	NumType=Card	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	supplemented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
57	with	_	ADP	_	_	_	_	_	_
58	fractions	_	NOUN	_	Number=Plur	_	_	_	_
59	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
60	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
61	promoter	_	NOUN	_	Number=Sing	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	binding	_	VERB	_	Number=Sing	_	_	_	_
64	protein	_	NOUN	_	Number=Sing	_	_	_	_
65	,	_	PUNCT	_	_	_	_	_	_
66	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	Addition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TFE	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	E	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	box	_	NOUN	_	Number=Sing	_	_	_	_
14	motif	_	NOUN	_	Number=Sing	_	_	_	_
15	upstream	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	LEF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	Ets	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	sites	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	further	_	ADJ	_	Degree=Pos	_	_	_	_
28	augments	_	NOUN	_	Number=Plur	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
32	system	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Individually	_	ADV	_	_	_	_	_	_
2	or	_	CCONJ	_	_	_	_	_	_
3	collectively	_	ADV	_	_	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	none	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	three	_	NUM	_	NumType=Card	_	_	_	_
9	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	LEF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	Ets	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	TFE	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	3	_	NUM	_	NumType=Card	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	could	_	AUX	_	VerbForm=Fin	_	_	_	_
28	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	absence	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	truncation	_	NOUN	_	Number=Sing	_	_	_	_
3	mutant	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	LEF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HMG	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	88	_	NUM	_	NumType=Card	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	HMG	_	PROPN	_	Number=Sing	_	_	_	_
18	box	_	NOUN	_	Number=Sing	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	lacks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	trans	_	NOUN	_	Number=Plur	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	domain	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	nucleosomal	_	ADJ	_	Degree=Pos	_	_	_	_
33	DNA	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
36	that	_	SCONJ	_	_	_	_	_	_
37	bending	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	DNA	_	NOUN	_	Number=Sing	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	HMG	_	PROPN	_	Number=Sing	_	_	_	_
43	domain	_	NOUN	_	Number=Sing	_	_	_	_
44	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	not	_	PART	_	_	_	_	_	_
46	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
47	to	_	PART	_	_	_	_	_	_
48	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
49	transcription	_	NOUN	_	Number=Sing	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	vitro	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	LEF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	vitro	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	chromatin	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	process	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	functional	_	ADJ	_	Degree=Pos	_	_	_	_
22	trans	_	NOUN	_	Number=Plur	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	domain	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	addition	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	HMG	_	PROPN	_	Number=Sing	_	_	_	_
31	domain	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003692	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	vitamin	_	ADJ	_	Number=Sing	_	_	_	_
6	D	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	rickets	_	NOUN	_	Number=Plur	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	II	_	NUM	_	NumType=Card	_	_	_	_
12	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	functional	_	ADJ	_	Degree=Pos	_	_	_	_
14	defects	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	alpha,25	_	NUM	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
21	D3	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	established	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	five	_	NUM	_	NumType=Card	_	_	_	_
8	patients	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
11	D	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	rickets	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	type	_	NOUN	_	Number=Sing	_	_	_	_
17	II	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	VDDR	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	II	_	NUM	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	lines	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	established	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	infection	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	T-lymphotrophic	_	ADJ	_	Degree=Pos	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	type	_	NOUN	_	Number=Sing	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	[	_	PUNCT	_	_	_	_	_	_
4	3H]1	_	NUM	_	NumType=Card	_	_	_	_
5	alpha,25	_	NUM	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
8	D3	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	1,25	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	OH	_	NOUN	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	D3	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	lines	_	NOUN	_	Number=Plur	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	binding	_	VERB	_	Number=Sing	_	_	_	_
28	studies	_	NOUN	_	Number=Plur	_	_	_	_
29	using	_	VERB	_	VerbForm=Ger	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	line	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	S	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	LB1	_	PROPN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	from	_	ADP	_	_	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	normal	_	ADJ	_	Degree=Pos	_	_	_	_
44	individual	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	1,25	_	NUM	_	NumType=Card	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	OH	_	INTJ	_	_	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	2D3	_	NUM	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	S	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	LB1	_	PROPN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	well	_	ADV	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	chick	_	NOUN	_	Number=Sing	_	_	_	_
20	intestinal	_	ADJ	_	Number=Sing	_	_	_	_
21	1,25	_	NUM	_	NumType=Card	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	OH	_	INTJ	_	_	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	2D3	_	NUM	_	NumType=Card	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	terms	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	ligand	_	NOUN	_	Number=Sing	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	affinity	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	capacity	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
38	mobility	_	NOUN	_	Number=Sing	_	_	_	_
39	on	_	ADP	_	_	_	_	_	_
40	5	_	NUM	_	NumType=Card	_	_	_	_
41	-	_	SYM	_	_	_	_	_	_
42	20	_	NUM	_	NumType=Card	_	_	_	_
43	%	_	SYM	_	Number=Sing	_	_	_	_
44	sucrose	_	ADJ	_	Number=Sing	_	_	_	_
45	gradients	_	NOUN	_	Number=Plur	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
49	adsorption	_	NOUN	_	Number=Sing	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	elution	_	VERB	_	Number=Sing	_	_	_	_
53	properties	_	NOUN	_	Number=Plur	_	_	_	_
54	from	_	ADP	_	_	_	_	_	_
55	DNA	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	cellulose	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Three	_	NUM	_	NumType=Card	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	patients	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	VDDR	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	II	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	Rh	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	VDR	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	Sh	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	VDR	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	Ab	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	VDR	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	no	_	DET	_	_	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	1,25	_	NUM	_	NumType=Card	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	OH	_	INTJ	_	_	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	D3	_	NOUN	_	Number=Sing	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	receptor	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	treatment	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	cultured	_	VERB	_	Degree=Pos	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	with	_	ADP	_	_	_	_	_	_
46	1,25	_	NUM	_	NumType=Card	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	OH	_	INTJ	_	_	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	2D3	_	NUM	_	Number=Sing	_	_	_	_
51	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
52	not	_	PART	_	_	_	_	_	_
53	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
54	production	_	NOUN	_	Number=Sing	_	_	_	_
55	of	_	ADP	_	_	_	_	_	_
56	24,25	_	NUM	_	NumType=Card	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	dihydroxy	_	NOUN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
61	D3	_	NOUN	_	Number=Sing	_	_	_	_
62	(	_	PUNCT	_	_	_	_	_	_
63	24,25	_	NUM	_	NumType=Card	_	_	_	_
64	(	_	PUNCT	_	_	_	_	_	_
65	OH	_	INTJ	_	_	_	_	_	_
66	)	_	PUNCT	_	_	_	_	_	_
67	2D3	_	NUM	_	NumType=Card	_	_	_	_
68	)	_	PUNCT	_	_	_	_	_	_
69	,	_	PUNCT	_	_	_	_	_	_
70	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
71	response	_	NOUN	_	Number=Sing	_	_	_	_
72	which	_	PRON	_	PronType=Rel	_	_	_	_
73	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
74	diagnostic	_	ADJ	_	Number=Sing	_	_	_	_
75	of	_	ADP	_	_	_	_	_	_
76	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
77	presence	_	NOUN	_	Number=Sing	_	_	_	_
78	of	_	ADP	_	_	_	_	_	_
79	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
80	functional	_	ADJ	_	Degree=Pos	_	_	_	_
81	1,25	_	NUM	_	NumType=Card	_	_	_	_
82	(	_	PUNCT	_	_	_	_	_	_
83	OH	_	INTJ	_	_	_	_	_	_
84	)	_	PUNCT	_	_	_	_	_	_
85	2	_	NUM	_	NumType=Card	_	_	_	_
86	D3	_	NOUN	_	Number=Sing	_	_	_	_
87	receptor	_	NOUN	_	Number=Sing	_	_	_	_
88	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	fourth	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	line	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	A1	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	VDR	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	1,25	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	OH	_	INTJ	_	_	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	2D3	_	NUM	_	Number=Sing	_	_	_	_
19	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	low	_	ADJ	_	Degree=Pos	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	capacity	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	25	_	NUM	_	NumType=Card	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	OH	_	INTJ	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	D3	_	NUM	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	24	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	hydroxylase	_	NOUN	_	Number=Sing	_	_	_	_
34	activity	_	NOUN	_	Number=Sing	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	not	_	PART	_	_	_	_	_	_
37	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	24,25	_	NUM	_	NumType=Card	_	_	_	_
4	-(	_	PUNCT	_	_	_	_	_	_
5	OH	_	NOUN	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	2D3	_	NUM	_	Number=Sing	_	_	_	_
8	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	1,25	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	OH	_	INTJ	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	2D3	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	fifth	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	line	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	Ro	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	VDR	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	although	_	SCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	hormone	_	VERB	_	Number=Sing	_	_	_	_
33	treatment	_	NOUN	_	Number=Sing	_	_	_	_
34	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
35	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
36	than	_	ADP	_	_	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	control	_	NOUN	_	Number=Sing	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	line	_	NOUN	_	Number=Sing	_	_	_	_
42	from	_	ADP	_	_	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	normal	_	ADJ	_	Degree=Pos	_	_	_	_
45	donor	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	capacity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	1,25	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	OH	_	INTJ	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	2D3	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	low	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	Ro-VDR	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	all	_	DET	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	where	_	ADV	_	PronType=Rel	_	_	_	_
6	1,25	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	OH	_	INTJ	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	2D3	_	NUM	_	Number=Sing	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	typical	_	ADJ	_	Degree=Pos	_	_	_	_
23	sedimentation	_	NOUN	_	Number=Sing	_	_	_	_
24	coefficient	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	3.7	_	NUM	_	NumType=Card	_	_	_	_
27	S	_	NOUN	_	Number=Sing	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	sucrose	_	NOUN	_	Number=Sing	_	_	_	_
30	density	_	NOUN	_	Number=Sing	_	_	_	_
31	gradient	_	NOUN	_	Degree=Pos	_	_	_	_
32	analysis	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	elution	_	ADJ	_	Degree=Pos	_	_	_	_
4	properties	_	NOUN	_	Number=Plur	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	cellulose	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	however	_	ADV	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	differed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	normal	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	both	_	CCONJ	_	_	_	_	_	_
17	Ro-VDR	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	A1	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	VDR	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	where	_	ADV	_	PronType=Rel	_	_	_	_
24	elution	_	NOUN	_	Number=Sing	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	DNA	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	cellulose	_	NOUN	_	Number=Sing	_	_	_	_
29	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	at	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
33	salt	_	NOUN	_	Number=Sing	_	_	_	_
34	concentration	_	NOUN	_	Number=Sing	_	_	_	_
35	than	_	ADP	_	_	_	_	_	_
36	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	typical	_	ADJ	_	Degree=Pos	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	1,25	_	NUM	_	NumType=Card	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	OH	_	INTJ	_	_	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	2D3	_	NUM	_	Number=Sing	_	_	_	_
45	receptor	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	Ro	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	VDR	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	typical	_	ADJ	_	Degree=Pos	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	localization	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	unoccupied	_	ADJ	_	Degree=Pos	_	_	_	_
13	1,25	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	OH	_	INTJ	_	_	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	2D3	_	NUM	_	NumType=Card	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	neither	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	unoccupied	_	ADJ	_	Degree=Pos	_	_	_	_
23	nor	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	occupied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	A1	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	VDR	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
33	completely	_	ADV	_	_	_	_	_	_
34	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	series	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	functional	_	ADJ	_	Degree=Pos	_	_	_	_
6	studies	_	NOUN	_	Number=Plur	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	modulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	level	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	mRNAs	_	PROPN	_	Number=Plur	_	_	_	_
17	coding	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	c-myc	_	ADJ	_	Number=Sing	_	_	_	_
22	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	growth	_	NOUN	_	Number=Sing	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
32	colony	_	NOUN	_	Number=Sing	_	_	_	_
33	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
34	activity	_	NOUN	_	Number=Sing	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	1,25	_	NUM	_	NumType=Card	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	OH	_	INTJ	_	_	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	2D3	_	NUM	_	Number=Sing	_	_	_	_
41	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	with	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	1,25	_	NUM	_	NumType=Card	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	OH	_	INTJ	_	_	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	2D3	_	NUM	_	NumType=Card	_	_	_	_
49	receptor	_	NOUN	_	Number=Sing	_	_	_	_
50	status	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
53	cells	_	NOUN	_	Number=Plur	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Use	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	lines	_	NOUN	_	Number=Plur	_	_	_	_
6	will	_	AUX	_	VerbForm=Fin	_	_	_	_
7	facilitate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	further	_	ADJ	_	Degree=Pos	_	_	_	_
9	study	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
13	defect	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	s	_	X	_	_	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	1,25	_	NUM	_	NumType=Card	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	OH	_	INTJ	_	_	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	2D3	_	NUM	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
28	D	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
31	rickets	_	NOUN	_	Number=Plur	_	_	_	_
32	type	_	NOUN	_	Number=Sing	_	_	_	_
33	II	_	NUM	_	NumType=Card	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	will	_	AUX	_	VerbForm=Fin	_	_	_	_
36	allow	_	VERB	_	VerbForm=Inf	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	correlation	_	NOUN	_	Number=Sing	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	impairment	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
43	functions	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003693	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	Treponema	_	PROPN	_	Number=Sing	_	_	_	_
8	pallidum	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	Borrelia	_	PROPN	_	Number=Sing	_	_	_	_
11	burgdorferi	_	NOUN	_	Number=Sing	_	_	_	_
12	lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
15	lipopeptides	_	NOUN	_	Number=Plur	_	_	_	_
16	proceeds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	via	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	pathway	_	NOUN	_	Number=Sing	_	_	_	_
20	distinct	_	NOUN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	activator	_	NOUN	_	Number=Sing	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	PROPN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	evidence	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Treponema	_	PROPN	_	Number=Sing	_	_	_	_
9	pallidum	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	Borrelia	_	PROPN	_	Number=Sing	_	_	_	_
12	burgdorferi	_	NOUN	_	Number=Plur	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	key	_	ADJ	_	Degree=Pos	_	_	_	_
15	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	mediators	_	NOUN	_	Number=Plur	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	syphilis	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	Lyme	_	PROPN	_	Number=Sing	_	_	_	_
21	disease	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	principal	_	ADJ	_	Degree=Pos	_	_	_	_
3	objective	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	present	_	ADJ	_	Degree=Pos	_	_	_	_
7	study	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
11	more	_	ADV	_	_	_	_	_	_
12	precisely	_	ADV	_	_	_	_	_	_
13	similarities	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	divergences	_	NOUN	_	Number=Plur	_	_	_	_
16	among	_	ADP	_	_	_	_	_	_
17	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	LPS	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	lipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	lipopeptide	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	immune	_	ADJ	_	Degree=Pos	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	signaling	_	NOUN	_	Number=Sing	_	_	_	_
31	events	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Like	_	ADP	_	_	_	_	_	_
2	LPS	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	native	_	ADJ	_	Number=Sing	_	_	_	_
6	B.	_	PROPN	_	Number=Sing	_	_	_	_
7	burgdorferi	_	NOUN	_	Number=Sing	_	_	_	_
8	OspA	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
11	analogs	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	OspA	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	OspB	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	two	_	NUM	_	NumType=Card	_	_	_	_
19	T.	_	PROPN	_	Number=Sing	_	_	_	_
20	pallidum	_	NOUN	_	Number=Sing	_	_	_	_
21	lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	Tpp47	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	Tpp17	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	all	_	DET	_	_	_	_	_	_
28	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	translocation	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	THP	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	human	_	ADJ	_	Degree=Pos	_	_	_	_
39	monocytoid	_	NOUN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Acylation	_	PROPN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	OspA	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
7	peptides	_	NOUN	_	Number=Plur	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	requisite	_	ADJ	_	Degree=Pos	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Polymyxin	_	PROPN	_	Number=Sing	_	_	_	_
2	B	_	PROPN	_	Number=Sing	_	_	_	_
3	abrogated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	only	_	ADV	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	LPS	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	70Z/3	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	pre-B	_	ADJ	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	lines	_	NOUN	_	Number=Plur	_	_	_	_
10	either	_	CCONJ	_	_	_	_	_	_
11	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	CD14	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	LPS	_	NOUN	_	Number=Sing	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	CD14	_	PROPN	_	Number=Sing	_	_	_	_
30	imparted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	LPS	_	NOUN	_	Number=Sing	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	not	_	ADV	_	_	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	OspA	_	NOUN	_	Number=Sing	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	spirochetal	_	ADJ	_	Degree=Pos	_	_	_	_
40	lipopeptides	_	NOUN	_	Number=Plur	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	assessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	induction	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	NF	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	kappa	_	NOUN	_	Number=Sing	_	_	_	_
49	B	_	NOUN	_	Number=Sing	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	expression	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	surface	_	NOUN	_	Number=Sing	_	_	_	_
54	immunoglobulin	_	NOUN	_	Number=Sing	_	_	_	_
55	M	_	NOUN	_	Number=Sing	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	biological	_	ADJ	_	Degree=Pos	_	_	_	_
5	relevance	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	observation	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	T.	_	PROPN	_	Number=Sing	_	_	_	_
11	pallidum	_	ADJ	_	Number=Sing	_	_	_	_
12	lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	lipopeptides	_	NOUN	_	Number=Plur	_	_	_	_
15	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	both	_	CCONJ	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	supported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	ability	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
34	analogs	_	NOUN	_	Number=Plur	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
37	human	_	ADJ	_	Degree=Pos	_	_	_	_
38	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
39	virus	_	NOUN	_	Number=Sing	_	_	_	_
40	replication	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	chronically	_	ADV	_	_	_	_	_	_
43	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	U1	_	PROPN	_	Number=Sing	_	_	_	_
45	monocytoid	_	NOUN	_	Degree=Pos	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	;	_	PUNCT	_	_	_	_	_	_
48	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
49	observations	_	NOUN	_	Number=Plur	_	_	_	_
50	also	_	ADV	_	_	_	_	_	_
51	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
52	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
53	potential	_	ADJ	_	Degree=Pos	_	_	_	_
54	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
55	whereby	_	ADV	_	_	_	_	_	_
56	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
57	syphilitic	_	ADJ	_	Degree=Pos	_	_	_	_
58	chancre	_	NOUN	_	Number=Sing	_	_	_	_
59	can	_	AUX	_	VerbForm=Fin	_	_	_	_
60	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
61	as	_	ADP	_	_	_	_	_	_
62	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
63	cofactor	_	NOUN	_	Number=Sing	_	_	_	_
64	for	_	ADP	_	_	_	_	_	_
65	human	_	ADJ	_	Degree=Pos	_	_	_	_
66	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
67	virus	_	NOUN	_	Number=Sing	_	_	_	_
68	transmission	_	NOUN	_	Number=Sing	_	_	_	_
69	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	data	_	NOUN	_	Number=Sing	_	_	_	_
4	lend	_	VERB	_	Number=Sing	_	_	_	_
5	additional	_	ADJ	_	Degree=Pos	_	_	_	_
6	support	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	proposal	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	spirochetal	_	ADJ	_	Degree=Pos	_	_	_	_
12	lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	LPS	_	PROPN	_	Number=Sing	_	_	_	_
15	initiate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	via	_	ADP	_	_	_	_	_	_
19	different	_	ADJ	_	Degree=Pos	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	surface	_	NOUN	_	Number=Sing	_	_	_	_
22	events	_	NOUN	_	Number=Plur	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	signaling	_	NOUN	_	Number=Sing	_	_	_	_
27	pathways	_	NOUN	_	Number=Plur	_	_	_	_
28	ultimately	_	ADV	_	_	_	_	_	_
29	converge	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
32	qualitatively	_	ADV	_	_	_	_	_	_
33	similar	_	ADJ	_	Degree=Pos	_	_	_	_
34	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
35	responses	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003702	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Barr	_	PROPN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	latency	_	NOUN	_	Number=Sing	_	_	_	_
7	BamHI	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Q	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	positively	_	ADV	_	_	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	STATs	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	Zta	_	PROPN	_	Number=Sing	_	_	_	_
18	interference	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	JAK	_	PROPN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	STAT	_	PROPN	_	Number=Sing	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	loss	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	BamHI	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	Q	_	NOUN	_	Number=Sing	_	_	_	_
31	promoter	_	NOUN	_	Number=Sing	_	_	_	_
32	activity	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Barr	_	PROPN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	EBV	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	tumors	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	nonimmunocompromised	_	ADJ	_	Degree=Pos	_	_	_	_
14	patients	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	EBV	_	PROPN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	highly	_	ADV	_	_	_	_	_	_
21	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	EBV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	antigen	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	whereas	_	SCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	immunogenic	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
19	EBNAs	_	NOUN	_	Number=Plur	_	_	_	_
20	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	pattern	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	generated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	usage	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	BamHI	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	Q	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	Qp	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	JAK	_	PROPN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	STAT	_	PROPN	_	Number=Sing	_	_	_	_
9	pathway	_	NOUN	_	Number=Sing	_	_	_	_
10	positively	_	ADV	_	_	_	_	_	_
11	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	Qp	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	transient	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	transfection	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	Qp	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CAT	_	NOUN	_	Number=Sing	_	_	_	_
11	reporter	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	cotransfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	JAK	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	treatment	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	6	_	NUM	_	NumType=Card	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Qp	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
7	signal	_	NOUN	_	Number=Sing	_	_	_	_
8	transducer	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	activator	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	STAT	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	directly	_	ADV	_	_	_	_	_	_
19	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
22	mobility	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	shift	_	NOUN	_	Number=Sing	_	_	_	_
25	assay	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	mutation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	potential	_	ADJ	_	Degree=Pos	_	_	_	_
31	STAT	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	binding	_	NOUN	_	Degree=Pos	_	_	_	_
34	sites	_	NOUN	_	Number=Plur	_	_	_	_
35	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	Qp	_	NOUN	_	Number=Sing	_	_	_	_
37	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	Janus	_	PROPN	_	Number=Sing	_	_	_	_
40	kinase	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	JAK	_	PROPN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	STATs	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	Qp	_	NOUN	_	Number=Sing	_	_	_	_
9	function	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	Qp	_	NOUN	_	Number=Sing	_	_	_	_
12	using	_	VERB	_	VerbForm=Ger	_	_	_	_
13	Burkitt	_	PROPN	_	Number=Sing	_	_	_	_
14	's	_	PART	_	_	_	_	_	_
15	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
16	Rael	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	cultured	_	VERB	_	Degree=Pos	_	_	_	_
20	nasopharyngeal	_	ADJ	_	Degree=Pos	_	_	_	_
21	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	NPC	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
28	STAT	_	NOUN	_	Number=Sing	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	inability	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	maintain	_	VERB	_	VerbForm=Inf	_	_	_	_
8	EBV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	positive	_	ADJ	_	Degree=Pos	_	_	_	_
11	NPC	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	lines	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	culture	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	related	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	Qp	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Passaging	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NPC	_	PROPN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	line	_	NOUN	_	Number=Sing	_	_	_	_
7	HK666	_	NOUN	_	Number=Sing	_	_	_	_
8	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	BZLF1	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	Zta	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	loss	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	Qp	_	NOUN	_	Number=Sing	_	_	_	_
23	function	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	assays	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	Zta	_	PROPN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	down	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Qp	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Zta	_	PROPN	_	Number=Sing	_	_	_	_
4	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	Qp	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	reporter	_	NOUN	_	Number=Sing	_	_	_	_
9	assays	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	negative	_	ADJ	_	Degree=Pos	_	_	_	_
3	regulation	_	NOUN	_	Number=Sing	_	_	_	_
4	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	Zta	_	PROPN	_	Number=Sing	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	evidence	_	NOUN	_	Number=Sing	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Zta	_	PROPN	_	Number=Sing	_	_	_	_
6	up	_	ADP	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	p53	_	NOUN	_	Number=Sing	_	_	_	_
11	leads	_	NOUN	_	Number=Plur	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	p53-mediated	_	VERB	_	Degree=Pos	_	_	_	_
14	interference	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	JAK	_	PROPN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	STAT	_	PROPN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	Qp	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	imply	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	JAK	_	PROPN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	STAT	_	PROPN	_	Number=Sing	_	_	_	_
8	signaling	_	NOUN	_	Number=Sing	_	_	_	_
9	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	EBV	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	malignancies	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003706	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Lipopolysaccharide	_	PROPN	_	Number=Sing	_	_	_	_
2	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	MAD3	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	c	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	Rel	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	related	_	ADJ	_	Degree=Pos	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
22	THP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Many	_	ADJ	_	Degree=Pos	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	LPS	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	including	_	VERB	_	VerbForm=Ger	_	_	_	_
13	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	DNA	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	binding	_	VERB	_	Number=Sing	_	_	_	_
35	proteins	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	members	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	Rel	_	NOUN	_	Number=Sing	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	family	_	NOUN	_	Number=Sing	_	_	_	_
17	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	LPS	_	NOUN	_	Number=Sing	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
26	through	_	ADP	_	_	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	LPS	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	signals	_	NOUN	_	Number=Plur	_	_	_	_
32	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	transduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	LPS	_	PROPN	_	Number=Sing	_	_	_	_
6	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	p50	_	NOUN	_	Number=Sing	_	_	_	_
13	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
14	as	_	ADV	_	_	_	_	_	_
15	well	_	ADV	_	Degree=Pos	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	p50/p65	_	NUM	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	DNA	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	complexes	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
33	THP	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	localization	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	concomitantly	_	ADV	_	_	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
11	decrease	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	independent	_	ADJ	_	Degree=Pos	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
21	ester	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	kinase	_	NOUN	_	Number=Sing	_	_	_	_
26	C.	_	PROPN	_	Number=Sing	_	_	_	_
27	Within	_	ADP	_	_	_	_	_	_
28	24	_	NUM	_	NumType=Card	_	_	_	_
29	h	_	NOUN	_	Number=Sing	_	_	_	_
30	following	_	VERB	_	VerbForm=Ger	_	_	_	_
31	LPS	_	NOUN	_	Number=Sing	_	_	_	_
32	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
33	there	_	ADV	_	_	_	_	_	_
34	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	striking	_	ADJ	_	Degree=Pos	_	_	_	_
37	increase	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	levels	_	NOUN	_	Number=Plur	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	p105	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	p50	_	NOUN	_	Number=Sing	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	proteins	_	NOUN	_	Number=Plur	_	_	_	_
7	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	increases	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	amounts	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
16	during	_	ADP	_	_	_	_	_	_
17	LPS	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	THP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	NOUN	_	Number=Sing	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	THP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	MAD3	_	PROPN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	an	_	CCONJ	_	Definite=Ind|PronType=Art	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	VERB	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	like	_	ADP	_	Degree=Pos	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
25	increase	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	MAD3	_	PROPN	_	Number=Sing	_	_	_	_
28	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	increase	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	MAD3	_	PROPN	_	Number=Sing	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	h	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	LPS	_	PROPN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	results	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	p50	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	p50/p65	_	NUM	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	MAD3	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003707	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NFATp	_	PROPN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	cyclosporin	_	VERB	_	Number=Sing	_	_	_	_
7	A	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
10	tumor	_	NOUN	_	Number=Sing	_	_	_	_
11	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	tumor	_	NOUN	_	Number=Sing	_	_	_	_
3	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
15	early	_	ADJ	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	in	_	SCONJ	_	_	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	rapidly	_	ADV	_	_	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	without	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	requirement	_	NOUN	_	Number=Sing	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	protein	_	NOUN	_	Number=Sing	_	_	_	_
33	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Maximal	_	ADJ	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	alpha	_	PROPN	_	Number=Sing	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	treatment	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	calcium	_	NOUN	_	Number=Sing	_	_	_	_
17	ionophores	_	NOUN	_	Number=Plur	_	_	_	_
18	alone	_	ADV	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	via	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
25	process	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
31	A	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	calcium	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	cyclosporin	_	VERB	_	Number=Sing	_	_	_	_
21	A	_	NOUN	_	Definite=Ind|PronType=Art	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
24	induction	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	TNF	_	PROPN	_	Number=Sing	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
18	DNA	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	NFATp	_	NOUN	_	_	_	_	_	_
2	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	sites	_	NOUN	_	Number=Plur	_	_	_	_
6	within	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	occupancy	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	both	_	DET	_	_	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	TNF	_	PROPN	_	Number=Sing	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	induction	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	although	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	little	_	ADJ	_	Degree=Pos	_	_	_	_
10	sequence	_	NOUN	_	Number=Sing	_	_	_	_
11	similarity	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	other	_	ADJ	_	Degree=Pos	_	_	_	_
14	NFATp	_	NOUN	_	Number=Plur	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	NOUN	_	Degree=Pos	_	_	_	_
17	sites	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
20	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	function	_	NOUN	_	VerbForm=Inf	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	element	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	T	_	PROPN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	virtue	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
37	ability	_	NOUN	_	Number=Sing	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
40	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	involvement	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	TNF	_	PROPN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	important	_	ADJ	_	Degree=Pos	_	_	_	_
25	role	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	coordinate	_	ADJ	_	Degree=Pos	_	_	_	_
29	induction	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
32	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
33	genes	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	starting	_	VERB	_	VerbForm=Ger	_	_	_	_
36	at	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	earliest	_	ADJ	_	Degree=Sup	_	_	_	_
39	stages	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	T	_	NOUN	_	Number=Sing	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	activation	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003710	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Comparison	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
4	acid	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
7	myristate	_	NOUN	_	Number=Sing	_	_	_	_
8	acetate	_	NOUN	_	Number=Sing	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	inducers	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
4	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	lines	_	NOUN	_	Number=Plur	_	_	_	_
7	growing	_	VERB	_	VerbForm=Ger	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	vitro	_	NOUN	_	Number=Sing	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	more	_	ADJ	_	Degree=Cmp	_	_	_	_
17	mature	_	ADJ	_	Degree=Pos	_	_	_	_
18	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	like	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	treatment	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	kinase	_	NOUN	_	Number=Sing	_	_	_	_
29	C	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
32	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
33	esters	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	such	_	ADJ	_	Degree=Pos	_	_	_	_
36	as	_	ADP	_	_	_	_	_	_
37	PMA	_	PROPN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	PMA	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	THP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
13	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	line	_	NOUN	_	Number=Sing	_	_	_	_
16	acquire	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	like	_	ADP	_	Degree=Pos	_	_	_	_
20	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
21	after	_	ADP	_	_	_	_	_	_
22	treatment	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	all	_	DET	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	trans	_	NOUN	_	Number=Plur	_	_	_	_
27	retinoic	_	PROPN	_	Number=Sing	_	_	_	_
28	acid	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	RA	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	signal	_	NOUN	_	Number=Sing	_	_	_	_
5	transduction	_	NOUN	_	Number=Sing	_	_	_	_
6	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	RA	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	first	_	ADV	_	_	_	_	_	_
13	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	effects	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	PMA	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	RA	_	PROPN	_	Number=Sing	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	be	_	AUX	_	VerbForm=Inf	_	_	_	_
30	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	during	_	ADP	_	_	_	_	_	_
32	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
33	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	RA	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	PMA	_	PROPN	_	Number=Sing	_	_	_	_
5	effectively	_	ADV	_	_	_	_	_	_
6	down	_	ADV	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	while	_	SCONJ	_	_	_	_	_	_
13	c-myb	_	VERB	_	Degree=Pos	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	only	_	ADV	_	_	_	_	_	_
17	after	_	ADP	_	_	_	_	_	_
18	PMA	_	NOUN	_	Number=Sing	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	beta	_	NOUN	_	Number=Sing	_	_	_	_
5	2-integrin	_	NOUN	_	Degree=Pos	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	CD11a	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	clearly	_	ADV	_	_	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	after	_	ADP	_	_	_	_	_	_
16	both	_	DET	_	_	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
19	treatments	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	src	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	family	_	NOUN	_	Number=Sing	_	_	_	_
8	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	different	_	ADJ	_	Degree=Pos	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	hck	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	similarly	_	ADV	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	agents	_	NOUN	_	Number=Plur	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	lyn	_	PROPN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	stronger	_	ADJ	_	Degree=Cmp	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	more	_	ADV	_	_	_	_	_	_
29	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
30	after	_	ADP	_	_	_	_	_	_
31	RA	_	NOUN	_	Number=Sing	_	_	_	_
32	treatment	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	RA	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	lyn	_	PROPN	_	Number=Sing	_	_	_	_
5	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
6	production	_	NOUN	_	Number=Sing	_	_	_	_
7	rapidly	_	ADV	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	HL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	60	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	lyn	_	ADJ	_	Degree=Pos	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	common	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
27	maturation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
30	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	AP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	involved	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	RA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	THP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	transiently	_	ADV	_	_	_	_	_	_
25	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
29	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
30	transferase	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	CAT	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	reporter	_	NOUN	_	Number=Sing	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
38	5	_	NUM	_	NumType=Card	_	_	_	_
39	copies	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	AP	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	binding	_	NOUN	_	Number=Sing	_	_	_	_
46	sites	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	PMA	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	RA	_	PROPN	_	Number=Sing	_	_	_	_
7	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
10	any	_	DET	_	_	_	_	_	_
11	CAT	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	thus	_	ADV	_	_	_	_	_	_
18	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	RA	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	changes	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	above	_	ADV	_	_	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
36	on	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	AP	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
42	activity	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003718	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Modulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	E2F	_	NOUN	_	Number=Sing	_	_	_	_
4	complexes	_	NOUN	_	Number=Plur	_	_	_	_
5	during	_	ADP	_	_	_	_	_	_
6	G0	_	PROPN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	S	_	PROPN	_	Number=Sing	_	_	_	_
9	phase	_	NOUN	_	Number=Sing	_	_	_	_
10	transition	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	primary	_	ADJ	_	Degree=Pos	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	pocket	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	E2F	_	NOUN	_	Number=Sing	_	_	_	_
6	complexes	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	convergence	_	NOUN	_	Number=Sing	_	_	_	_
9	points	_	NOUN	_	Number=Plur	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	cycle	_	NOUN	_	Number=Sing	_	_	_	_
13	signaling	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	report	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	monitored	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	pocket	_	NOUN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	E2F	_	NOUN	_	Number=Sing	_	_	_	_
15	complexes	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	primary	_	ADJ	_	Degree=Pos	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	after	_	ADP	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
26	12	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	myristate	_	NOUN	_	Number=Sing	_	_	_	_
29	13	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	acetate	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	previous	_	ADJ	_	Degree=Pos	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	mouse	_	NOUN	_	Number=Sing	_	_	_	_
9	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	T-lymphocytes	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	E2F4	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	DP1	_	NOUN	_	Number=Sing	_	_	_	_
16	form	_	NOUN	_	Number=Sing	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	predominant	_	ADJ	_	Degree=Pos	_	_	_	_
19	E2F	_	PROPN	_	Number=Sing	_	_	_	_
20	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
21	both	_	CCONJ	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	G0	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	G1	_	NOUN	_	Number=Sing	_	_	_	_
26	phases	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	cycle	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	whereas	_	SCONJ	_	_	_	_	_	_
37	E2F1	_	PROPN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	3	_	NUM	_	NumType=Card	_	_	_	_
41	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
42	first	_	ADV	_	_	_	_	_	_
43	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	late	_	ADJ	_	Degree=Pos	_	_	_	_
46	G1	_	PROPN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
50	expression	_	NOUN	_	Number=Sing	_	_	_	_
51	levels	_	NOUN	_	Number=Plur	_	_	_	_
52	increase	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
53	towards	_	ADP	_	_	_	_	_	_
54	S	_	NOUN	_	Number=Sing	_	_	_	_
55	phase	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Intriguingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	major	_	ADJ	_	Degree=Pos	_	_	_	_
5	E2F	_	NOUN	_	Number=Sing	_	_	_	_
6	complex	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	detected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	quiescent	_	ADJ	_	Degree=Pos	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	consisted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	pRB	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	E2F4	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	DP1	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Though	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	DP1	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	increase	_	NOUN	_	Number=Sing	_	_	_	_
10	when	_	ADV	_	PronType=Int	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	progress	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	G0	_	PROPN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	S	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	proportion	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	DP1	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	DP2	_	NOUN	_	Number=Sing	_	_	_	_
24	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	relatively	_	ADV	_	_	_	_	_	_
26	constant	_	ADJ	_	Degree=Pos	_	_	_	_
27	during	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	cycle	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	increase	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
8	mobility	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	predominant	_	ADJ	_	Degree=Pos	_	_	_	_
12	E2F	_	NOUN	_	Number=Sing	_	_	_	_
13	components	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	DP1	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	E2F4	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	progressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	G0	_	PROPN	_	Number=Sing	_	_	_	_
26	into	_	ADP	_	_	_	_	_	_
27	early	_	ADJ	_	Degree=Pos	_	_	_	_
28	G1	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	increase	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	mobility	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	attributable	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	as	_	SCONJ	_	_	_	_	_	_
11	lambda	_	PROPN	_	Number=Sing	_	_	_	_
12	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
13	treatment	_	NOUN	_	Number=Sing	_	_	_	_
14	could	_	AUX	_	VerbForm=Fin	_	_	_	_
15	convert	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	slower	_	ADJ	_	Degree=Cmp	_	_	_	_
18	migrating	_	NOUN	_	VerbForm=Ger	_	_	_	_
19	forms	_	NOUN	_	Number=Plur	_	_	_	_
20	into	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
23	faster	_	ADJ	_	Degree=Cmp	_	_	_	_
24	mobility	_	NOUN	_	Number=Sing	_	_	_	_
25	forms	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	change	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	status	_	NOUN	_	Number=Sing	_	_	_	_
10	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	decrease	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	DNA	_	NOUN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	modulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	DNA	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	VERB	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	DP1	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	E2F4	_	NOUN	_	Number=Sing	_	_	_	_
15	could	_	AUX	_	VerbForm=Fin	_	_	_	_
16	help	_	VERB	_	VerbForm=Inf	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	lack	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	vivo	_	NOUN	_	Number=Sing	_	_	_	_
24	DNA	_	PROPN	_	Number=Sing	_	_	_	_
25	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	late	_	ADJ	_	Degree=Pos	_	_	_	_
28	G1	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	S	_	NOUN	_	Number=Sing	_	_	_	_
31	phases	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	promoters	_	NOUN	_	Number=Plur	_	_	_	_
35	negatively	_	ADV	_	_	_	_	_	_
36	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	through	_	ADP	_	_	_	_	_	_
38	E2F	_	NOUN	_	Number=Sing	_	_	_	_
39	sites	_	NOUN	_	Number=Plur	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	novel	_	NOUN	_	Number=Sing	_	_	_	_
44	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
45	for	_	SCONJ	_	_	_	_	_	_
46	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
47	E2F	_	NOUN	_	Number=Sing	_	_	_	_
48	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
49	activity	_	NOUN	_	Number=Sing	_	_	_	_
50	during	_	ADP	_	_	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	transition	_	NOUN	_	Number=Sing	_	_	_	_
53	from	_	ADP	_	_	_	_	_	_
54	quiescence	_	NOUN	_	Number=Sing	_	_	_	_
55	to	_	ADP	_	_	_	_	_	_
56	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003719	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	SCL	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	related	_	ADJ	_	Degree=Pos	_	_	_	_
4	hemopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
5	helix	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	loop	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	helix	_	NOUN	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	helix	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	loop	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	helix	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HLH	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	family	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	critical	_	ADJ	_	Degree=Pos	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	development	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	species	_	NOUN	_	Number=Plur	_	_	_	_
27	ranging	_	VERB	_	VerbForm=Ger	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	plants	_	NOUN	_	Number=Plur	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	mammals	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Five	_	NUM	_	NumType=Card	_	_	_	_
2	members	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	family	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	MYC	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	SCL	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	TAL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	LYL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	E2A	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	oncogenic	_	ADJ	_	Degree=Pos	_	_	_	_
25	events	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
29	tumors	_	NOUN	_	Number=Plur	_	_	_	_
30	because	_	ADP	_	_	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
33	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
34	involvement	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
37	translocations	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	leukemias	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	SCL	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	LYL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	low	_	ADJ	_	Degree=Pos	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	undetectable	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	normal	_	ADJ	_	Degree=Pos	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	populations	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	SCL	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	megakaryocyte	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	mast	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	populations	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	same	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	lineages	_	NOUN	_	Number=Plur	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	GATA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	zinc	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	finger	_	NOUN	_	Number=Sing	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	SCL	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	GATA	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	undergo	_	VERB	_	Number=Sing	_	_	_	_
11	coordinate	_	ADJ	_	Degree=Pos	_	_	_	_
12	modulation	_	NOUN	_	Number=Sing	_	_	_	_
13	during	_	ADP	_	_	_	_	_	_
14	chemically	_	ADV	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	mouse	_	NOUN	_	Number=Sing	_	_	_	_
20	erythroleukemia	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	down	_	ADV	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	modulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	during	_	ADP	_	_	_	_	_	_
28	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
29	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	K562	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	thus	_	ADV	_	_	_	_	_	_
36	implying	_	VERB	_	VerbForm=Ger	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	role	_	NOUN	_	Number=Sing	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	SCL	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
43	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
44	events	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	contrast	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	GATA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	SCL	_	PROPN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	developing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	brain	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	function	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	SCL	_	PROPN	_	Number=Sing	_	_	_	_
7	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	also	_	ADV	_	_	_	_	_	_
11	important	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	self	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	renewal	_	NOUN	_	Number=Sing	_	_	_	_
18	events	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003722	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
7	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	lines	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Role	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	motifs	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	stabilization	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
3	TNF	_	PROPN	_	Number=Sing	_	_	_	_
4	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	many	_	ADJ	_	Degree=Pos	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	pathologic	_	ADJ	_	Degree=Pos	_	_	_	_
9	signs	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cachexia	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	current	_	ADJ	_	Degree=Pos	_	_	_	_
3	work	_	NOUN	_	Number=Sing	_	_	_	_
4	describes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	lines	_	NOUN	_	Number=Plur	_	_	_	_
14	after	_	ADP	_	_	_	_	_	_
15	PMA	_	PROPN	_	Number=Sing	_	_	_	_
16	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	exhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	low	_	ADJ	_	Degree=Pos	_	_	_	_
7	level	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
10	TNF	_	ADJ	_	Number=Sing	_	_	_	_
11	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Within	_	ADP	_	_	_	_	_	_
2	2	_	NUM	_	NumType=Card	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	4	_	NUM	_	NumType=Card	_	_	_	_
5	h	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	PMA	_	NOUN	_	Number=Sing	_	_	_	_
8	exposure	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	steady	_	ADJ	_	Degree=Pos	_	_	_	_
11	state	_	NOUN	_	Number=Sing	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	markedly	_	ADV	_	_	_	_	_	_
18	elevated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	all	_	DET	_	_	_	_	_	_
21	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	lines	_	NOUN	_	Number=Plur	_	_	_	_
24	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	rise	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	due	_	ADP	_	_	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	stability	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	almost	_	ADV	_	_	_	_	_	_
14	twofold	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	overall	_	ADJ	_	Degree=Pos	_	_	_	_
20	increase	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	rises	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	more	_	ADJ	_	Degree=Cmp	_	_	_	_
28	than	_	ADP	_	_	_	_	_	_
29	sixfold	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	level	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	DNase	_	NOUN	_	Number=Sing	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	within	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	TNF	_	PROPN	_	Number=Sing	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	between	_	ADP	_	_	_	_	_	_
22	-	_	SYM	_	_	_	_	_	_
23	200	_	NUM	_	NumType=Card	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	100	_	NUM	_	NumType=Card	_	_	_	_
27	bp	_	NOUN	_	Number=Sing	_	_	_	_
28	relative	_	ADV	_	_	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	initiation	_	NOUN	_	Number=Sing	_	_	_	_
33	site	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	absent	_	ADJ	_	Degree=Pos	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	nonexpressing	_	ADJ	_	Degree=Pos	_	_	_	_
5	erythroleukemia	_	NOUN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	lines	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	DNase	_	NOUN	_	Number=Sing	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	present	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	uninduced	_	ADJ	_	Degree=Pos	_	_	_	_
17	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	changed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	after	_	ADP	_	_	_	_	_	_
25	PMA	_	NOUN	_	Number=Sing	_	_	_	_
26	induction	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	PMA	_	PROPN	_	Number=Sing	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	c	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	fos	_	ADP	_	_	_	_	_	_
8	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
9	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	well	_	ADV	_	Degree=Pos	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	TNF	_	ADJ	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	;	_	PUNCT	_	_	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
20	other	_	ADJ	_	Degree=Pos	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	AP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	complex	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	junB	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	junD	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	also	_	ADV	_	_	_	_	_	_
35	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	PMA	_	PROPN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	extracts	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	SCONJ	_	_	_	_	_	_
5	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	ML	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	specifically	_	ADV	_	_	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	AP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	PROPN	_	Number=Sing	_	_	_	_
30	sequence	_	NOUN	_	Number=Sing	_	_	_	_
31	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	within	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	TNF	_	PROPN	_	Number=Sing	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	PMA	_	PROPN	_	Number=Sing	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	level	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	number	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	complexes	_	NOUN	_	Number=Plur	_	_	_	_
13	relative	_	ADV	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	resting	_	NOUN	_	VerbForm=Ger	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	murine	_	NOUN	_	Number=Sing	_	_	_	_
9	TNF	_	NOUN	_	Number=Sing	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003724	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	c	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	Rel	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
8	target	_	NOUN	_	Number=Sing	_	_	_	_
9	sequences	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	I	_	PRON	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	type	_	NOUN	_	Number=Sing	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
6	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
15	growth	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
18	transformation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	development	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	acute	_	ADJ	_	Degree=Pos	_	_	_	_
32	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
33	malignancy	_	NOUN	_	Number=Sing	_	_	_	_
34	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	adult	_	NOUN	_	Number=Sing	_	_	_	_
36	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
37	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	characteristic	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	I-transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	Rel	_	NOUN	_	Number=Sing	_	_	_	_
20	family	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	be	_	AUX	_	VerbForm=Inf	_	_	_	_
29	essential	_	ADJ	_	Degree=Pos	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	growth	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
35	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	Rel	_	NOUN	_	Number=Sing	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
16	growth	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
28	how	_	ADV	_	PronType=Int	_	_	_	_
29	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
30	participate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	independent	_	ADJ	_	Degree=Pos	_	_	_	_
38	growth	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	I	_	PRON	_	NumType=Card	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	certain	_	ADJ	_	Degree=Pos	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	Rel	_	NOUN	_	Number=Sing	_	_	_	_
14	members	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	predominantly	_	ADV	_	_	_	_	_	_
17	c-Rel	_	ADJ	_	Degree=Pos	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	interact	_	VERB	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	sequences	_	NOUN	_	Number=Plur	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	key	_	ADJ	_	Degree=Pos	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
37	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Reporter	_	NOUN	_	Number=Sing	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	assays	_	NOUN	_	Number=Plur	_	_	_	_
4	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	c	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	Rel	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	present	_	VERB	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	Fc	_	PROPN	_	Number=Sing	_	_	_	_
20	gammaR1	_	NOUN	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	potent	_	VERB	_	VerbForm=Inf	_	_	_	_
25	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	c	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	Rel	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	Fc	_	PROPN	_	Number=Sing	_	_	_	_
9	gammaR1	_	NOUN	_	Number=Sing	_	_	_	_
10	STAT	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
17	blood	_	NOUN	_	Number=Sing	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	immortalized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vitro	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	levels	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	raise	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	possibility	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	Rel	_	PROPN	_	Number=Sing	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	growth	_	NOUN	_	Number=Sing	_	_	_	_
17	control	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	T	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	by	_	SCONJ	_	_	_	_	_	_
27	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
28	genes	_	NOUN	_	Number=Plur	_	_	_	_
29	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	both	_	CCONJ	_	_	_	_	_	_
32	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	certain	_	ADJ	_	Degree=Pos	_	_	_	_
35	STAT	_	NOUN	_	Number=Sing	_	_	_	_
36	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003727	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Erythropoietin	_	PROPN	_	Number=Sing	_	_	_	_
2	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	SCL	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	products	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	SCL	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	originally	_	ADV	_	_	_	_	_	_
12	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	through	_	ADP	_	_	_	_	_	_
14	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	involvement	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	recurrent	_	ADJ	_	Degree=Pos	_	_	_	_
19	chromosomal	_	ADJ	_	Number=Sing	_	_	_	_
20	translocation	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	most	_	ADV	_	_	_	_	_	_
25	frequent	_	ADJ	_	Degree=Pos	_	_	_	_
26	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
27	lesion	_	NOUN	_	Number=Sing	_	_	_	_
28	recognized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
31	acute	_	ADJ	_	Degree=Pos	_	_	_	_
32	lymphoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
33	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	products	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	basic	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	helix	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	loop	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	helix	_	NOUN	_	Number=Sing	_	_	_	_
16	motif	_	NOUN	_	Number=Sing	_	_	_	_
17	characteristic	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	large	_	ADJ	_	Degree=Pos	_	_	_	_
21	family	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factors	_	NOUN	_	Number=Plur	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	canonical	_	ADJ	_	Degree=Pos	_	_	_	_
30	DNA	_	PROPN	_	Number=Sing	_	_	_	_
31	sequence	_	NOUN	_	Number=Sing	_	_	_	_
32	CANNTG	_	PROPN	_	Number=Sing	_	_	_	_
33	as	_	ADP	_	_	_	_	_	_
34	protein	_	NOUN	_	Number=Sing	_	_	_	_
35	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	TAL1	_	NOUN	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	vivo	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	chemical	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	erythroleukemia	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	lines	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	vivo	_	NOUN	_	Number=Sing	_	_	_	_
18	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	might	_	AUX	_	VerbForm=Fin	_	_	_	_
22	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	aspects	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
26	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	terminal	_	ADJ	_	Number=Sing	_	_	_	_
4	events	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	erythropoiesis	_	NOUN	_	Number=Sing	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
12	hormone	_	NOUN	_	Number=Sing	_	_	_	_
13	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	Epo	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	whether	_	SCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	products	_	NOUN	_	Number=Plur	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	Epo	_	PROPN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	splenic	_	ADJ	_	Degree=Pos	_	_	_	_
39	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
40	from	_	ADP	_	_	_	_	_	_
41	mice	_	NOUN	_	Number=Plur	_	_	_	_
42	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	with	_	ADP	_	_	_	_	_	_
44	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
45	anemia	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
48	strain	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	Friend	_	NOUN	_	Number=Sing	_	_	_	_
51	virus	_	NOUN	_	Number=Sing	_	_	_	_
52	(	_	PUNCT	_	_	_	_	_	_
53	FVA	_	PROPN	_	Number=Sing	_	_	_	_
54	cells	_	NOUN	_	Number=Plur	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Epo	_	PROPN	_	Number=Sing	_	_	_	_
2	elicited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	dose	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	related	_	ADJ	_	Degree=Pos	_	_	_	_
9	increase	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
12	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	stabilizing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	one	_	NUM	_	NumType=Card	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	Epo	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	inducible	_	ADJ	_	Number=Sing	_	_	_	_
5	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
6	DNA	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	FVA	_	PROPN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	extracts	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	subsequently	_	ADV	_	_	_	_	_	_
18	decayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	despite	_	SCONJ	_	_	_	_	_	_
20	accumulating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	DNA	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	temporally	_	ADV	_	_	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	Epo	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Epo	_	PROPN	_	Number=Sing	_	_	_	_
6	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	at	_	ADP	_	_	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
16	locus	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	Friend	_	NOUN	_	Number=Sing	_	_	_	_
19	virus	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	establish	_	VERB	_	VerbForm=Inf	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	link	_	NOUN	_	Number=Sing	_	_	_	_
27	between	_	ADP	_	_	_	_	_	_
28	Epo	_	NOUN	_	Number=Sing	_	_	_	_
29	signaling	_	VERB	_	Number=Sing	_	_	_	_
30	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	member	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	family	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	factors	_	NOUN	_	Number=Plur	_	_	_	_
40	involved	_	ADJ	_	Degree=Pos	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
46	cell	_	NOUN	_	Number=Sing	_	_	_	_
47	lineages	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003731	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
2	proteins	_	NOUN	_	Number=Plur	_	_	_	_
3	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
9	virus	_	NOUN	_	Number=Sing	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	long	_	ADJ	_	Degree=Pos	_	_	_	_
13	terminal	_	NOUN	_	Number=Sing	_	_	_	_
14	repeat	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Three	_	NUM	_	NumType=Card	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	sites	_	NOUN	_	Number=Plur	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	C	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	EBP	_	NOUN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
15	virus	_	NOUN	_	Number=Sing	_	_	_	_
16	type	_	NOUN	_	Number=Sing	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	long	_	ADJ	_	Degree=Pos	_	_	_	_
24	terminal	_	NOUN	_	Number=Sing	_	_	_	_
25	repeat	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	LTR	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	V.M.	_	PROPN	_	Number=Sing	_	_	_	_
31	Tesmer	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	A.	_	PROPN	_	Number=Sing	_	_	_	_
34	Rajadhyaksha	_	PROPN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	J.Babin	_	PROPN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	M.Bina	_	PROPN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	Proc.Natl.Acad.Sci.	_	PROPN	_	Number=Sing	_	_	_	_
42	USA	_	PROPN	_	Number=Sing	_	_	_	_
43	90:7298-7302	_	NUM	_	NumType=Card	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	1993	_	NUM	_	NumType=Card	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	functional	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	LTR	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
4	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	using	_	VERB	_	VerbForm=Ger	_	_	_	_
8	either	_	CCONJ	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	excess	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	sites	_	NOUN	_	Number=Plur	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	trans	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
20	negative	_	ADJ	_	Degree=Pos	_	_	_	_
21	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
26	proteins	_	NOUN	_	Number=Plur	_	_	_	_
27	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	basal	_	ADJ	_	Degree=Pos	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	levels	_	NOUN	_	Number=Plur	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	HIV	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	LTR	_	NOUN	_	Number=Sing	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
43	cell	_	NOUN	_	Number=Sing	_	_	_	_
44	line	_	NOUN	_	Number=Sing	_	_	_	_
45	U937	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	RNA	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	blots	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	assays	_	NOUN	_	Number=Plur	_	_	_	_
9	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	IL6	_	PROPN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	only	_	ADV	_	Degree=Pos	_	_	_	_
17	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
19	family	_	NOUN	_	Number=Sing	_	_	_	_
20	member	_	NOUN	_	Number=Sing	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	when	_	ADV	_	PronType=Int	_	_	_	_
25	U937	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Mutational	_	ADJ	_	Degree=Pos	_	_	_	_
2	analyses	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	HIV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	LTR	_	NOUN	_	Number=Sing	_	_	_	_
9	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	one	_	NUM	_	NumType=Card	_	_	_	_
12	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	normal	_	ADJ	_	Degree=Pos	_	_	_	_
18	LTR	_	NOUN	_	Number=Sing	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	before	_	ADV	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	after	_	ADP	_	_	_	_	_	_
24	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	two	_	NUM	_	NumType=Card	_	_	_	_
30	3'	_	NOUN	_	NumType=Card	_	_	_	_
31	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
32	sites	_	NOUN	_	Number=Plur	_	_	_	_
33	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	functionally	_	ADV	_	_	_	_	_	_
35	equivalent	_	ADJ	_	Degree=Pos	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	crippled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
10	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
11	C	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	EBP	_	NOUN	_	Number=Sing	_	_	_	_
14	sites	_	NOUN	_	Number=Plur	_	_	_	_
15	can	_	AUX	_	VerbForm=Fin	_	_	_	_
16	still	_	ADV	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	following	_	VERB	_	VerbForm=Ger	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	U937	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	models	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	how	_	ADV	_	PronType=Int	_	_	_	_
7	elevated	_	ADJ	_	Degree=Pos	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	IL6	_	PROPN	_	Number=Sing	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	autostimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	loop	_	NOUN	_	Number=Sing	_	_	_	_
17	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	infection	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	cytokine	_	VERB	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	HIV	_	NOUN	_	Number=Sing	_	_	_	_
29	replication	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003732	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Effects	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	diesel	_	NOUN	_	Number=Sing	_	_	_	_
4	organic	_	ADJ	_	Degree=Pos	_	_	_	_
5	extracts	_	NOUN	_	Number=Plur	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
8	production	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
11	blood	_	NOUN	_	Number=Sing	_	_	_	_
12	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Polyaromatic	_	ADJ	_	Degree=Pos	_	_	_	_
4	hydrocarbons	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	PAHs	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	diesel	_	NOUN	_	Number=Sing	_	_	_	_
11	exhaust	_	NOUN	_	Number=Sing	_	_	_	_
12	particles	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	DEPs	_	NOUN	_	Number=Plur	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	atmospheric	_	ADJ	_	Degree=Pos	_	_	_	_
21	urban	_	ADJ	_	Degree=Pos	_	_	_	_
22	pollution	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Such	_	ADJ	_	Degree=Pos	_	_	_	_
2	compounds	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	favor	_	NOUN	_	VerbForm=Inf	_	_	_	_
8	IgE	_	NOUN	_	Number=Sing	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	bronchial	_	ADJ	_	Degree=Pos	_	_	_	_
12	hyperresponsiveness	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	airway	_	ADJ	_	Number=Sing	_	_	_	_
16	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Chemokines	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	group	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
8	involved	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	OBJECTIVE	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	DEP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	PAHs	_	NOUN	_	Number=Plur	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	release	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	8	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	MCP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	RANTES	_	NOUN	_	Number=Sing	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	PBMCs	_	PROPN	_	Number=Sing	_	_	_	_
28	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
31	subjects	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	production	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	supernatants	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	ELISA	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	semiquantitative	_	ADJ	_	Degree=Pos	_	_	_	_
17	RT	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	PCR	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Secretion	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	8	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	RANTES	_	PROPN	_	Number=Sing	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	dose	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
16	manner	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	DEP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	PAHs	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	range	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	0.5	_	NUM	_	NumType=Card	_	_	_	_
28	ng	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	50	_	NUM	_	NumType=Card	_	_	_	_
31	ng	_	NOUN	_	Number=Sing	_	_	_	_
32	/	_	SYM	_	_	_	_	_	_
33	mL	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	contrary	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	release	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	MCP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	significantly	_	ADV	_	_	_	_	_	_
13	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	dose	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
21	manner	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Messenger	_	PROPN	_	Number=Sing	_	_	_	_
2	RNA	_	PROPN	_	Number=Sing	_	_	_	_
3	production	_	NOUN	_	Number=Sing	_	_	_	_
4	coding	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	8	_	NUM	_	NumType=Card	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	RANTES	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	MCP	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	parallel	_	ADJ	_	Degree=Pos	_	_	_	_
18	variations	_	NOUN	_	Number=Plur	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	production	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	correspondent	_	NOUN	_	Number=Sing	_	_	_	_
25	proteins	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Effects	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	DEP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	PAHs	_	NOUN	_	Number=Plur	_	_	_	_
6	became	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	significant	_	ADJ	_	Degree=Pos	_	_	_	_
8	at	_	ADP	_	_	_	_	_	_
9	7	_	NUM	_	NumType=Card	_	_	_	_
10	hours	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	up	_	ADV	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	48	_	NUM	_	NumType=Card	_	_	_	_
15	hours	_	NOUN	_	Number=Plur	_	_	_	_
16	time	_	NOUN	_	Number=Sing	_	_	_	_
17	culture	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	MCP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	up	_	ADP	_	_	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	24	_	NUM	_	NumType=Card	_	_	_	_
27	hours	_	NOUN	_	Number=Plur	_	_	_	_
28	time	_	NOUN	_	Number=Sing	_	_	_	_
29	culture	_	NOUN	_	Number=Sing	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	8	_	NUM	_	NumType=Card	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	RANTES	_	PROPN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	supernatants	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	DEP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	PAH	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	controls	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	significantly	_	ADV	_	_	_	_	_	_
21	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
31	significantly	_	ADV	_	_	_	_	_	_
32	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	anti-IL	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	8	_	NUM	_	NumType=Card	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	anti-RANTES	_	ADJ	_	Degree=Pos	_	_	_	_
41	neutralizing	_	VERB	_	VerbForm=Ger	_	_	_	_
42	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	respectively	_	ADV	_	_	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSION	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
7	pathways	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	DEP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	PAHs	_	NOUN	_	Number=Plur	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	level	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	reinforcing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	idea	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	PRON	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	development	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	reactions	_	NOUN	_	Number=Plur	_	_	_	_
28	might	_	AUX	_	VerbForm=Fin	_	_	_	_
29	be	_	AUX	_	VerbForm=Inf	_	_	_	_
30	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	diesel	_	NOUN	_	Number=Sing	_	_	_	_
33	exhaust	_	NOUN	_	Number=Sing	_	_	_	_
34	emission	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003736	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Acetylsalicylic	_	PROPN	_	Number=Sing	_	_	_	_
2	acid	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	sodium	_	NOUN	_	Number=Sing	_	_	_	_
5	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
6	inhibit	_	VERB	_	Number=Sing	_	_	_	_
7	LPS	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	c	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	Rel	_	X	_	Number=Sing	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	translocation	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	tissue	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TF	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	tumor	_	NOUN	_	Number=Sing	_	_	_	_
19	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	alfa	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	TNF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	acetylsalicylic	_	ADJ	_	Degree=Pos	_	_	_	_
8	acid	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	sodium	_	NOUN	_	Number=Sing	_	_	_	_
11	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	LPS	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	pro-coagulant	_	ADJ	_	Degree=Pos	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	tissue	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	TF	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	pro-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
30	protein	_	NOUN	_	Number=Sing	_	_	_	_
31	tumor	_	NOUN	_	Number=Sing	_	_	_	_
32	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	alpha	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	TNF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	alpha	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	as	_	ADV	_	_	_	_	_	_
43	well	_	ADV	_	Degree=Pos	_	_	_	_
44	as	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	prostaglandin	_	NOUN	_	Number=Sing	_	_	_	_
47	PGE2	_	NOUN	_	Number=Sing	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	human	_	ADJ	_	Degree=Pos	_	_	_	_
50	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	drugs	_	NOUN	_	Number=Plur	_	_	_	_
3	dose	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	dependently	_	ADV	_	_	_	_	_	_
6	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	LPS	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	TF	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	level	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	PGE2	_	NOUN	_	Number=Sing	_	_	_	_
27	production	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	evidenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	electro	_	ADJ	_	Degree=Pos	_	_	_	_
5	mobility	_	NOUN	_	Number=Sing	_	_	_	_
6	shift	_	NOUN	_	Number=Sing	_	_	_	_
7	assay	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	use	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	prototypic	_	ADJ	_	Number=Sing	_	_	_	_
21	probe	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
24	drugs	_	NOUN	_	Number=Plur	_	_	_	_
25	probably	_	ADV	_	_	_	_	_	_
26	exert	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
29	effects	_	NOUN	_	Number=Plur	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	interference	_	NOUN	_	Number=Sing	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
35	translocation	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kappa	_	NOUN	_	Number=Sing	_	_	_	_
40	B/c	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	Rel	_	NOUN	_	Number=Sing	_	_	_	_
43	proteins	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	may	_	AUX	_	VerbForm=Fin	_	_	_	_
4	expand	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	understanding	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	anti-thrombotic	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	effects	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	drugs	_	NOUN	_	Number=Plur	_	_	_	_
16	when	_	ADV	_	PronType=Int	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003741	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	HLA	_	PROPN	_	Number=Sing	_	_	_	_
2	class	_	NOUN	_	Number=Sing	_	_	_	_
3	I	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	mediated	_	VERB	_	Degree=Pos	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
10	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
12	E-mediated	_	ADJ	_	Degree=Pos	_	_	_	_
13	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	Rb	_	NOUN	_	Number=Sing	_	_	_	_
16	function	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	E2F	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Chronic	_	ADJ	_	Degree=Pos	_	_	_	_
2	rejection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transplanted	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
5	organs	_	NOUN	_	Number=Plur	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	manifested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	blood	_	NOUN	_	Number=Sing	_	_	_	_
13	vessels	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	allograft	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	HLA	_	PROPN	_	Number=Sing	_	_	_	_
2	class	_	NOUN	_	Number=Sing	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	Ags	_	AUX	_	Number=Plur	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	play	_	VERB	_	VerbForm=Inf	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	major	_	ADJ	_	Degree=Pos	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
15	process	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	since	_	SCONJ	_	_	_	_	_	_
18	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
19	via	_	ADP	_	_	_	_	_	_
20	HLA	_	PROPN	_	Number=Sing	_	_	_	_
21	class	_	NOUN	_	Number=Sing	_	_	_	_
22	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
23	molecules	_	NOUN	_	Number=Plur	_	_	_	_
24	can	_	AUX	_	VerbForm=Fin	_	_	_	_
25	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	aortic	_	ADJ	_	Degree=Pos	_	_	_	_
30	endothelial	_	NOUN	_	Number=Sing	_	_	_	_
31	as	_	ADV	_	_	_	_	_	_
32	well	_	ADV	_	Degree=Pos	_	_	_	_
33	as	_	ADP	_	_	_	_	_	_
34	smooth	_	ADJ	_	Degree=Pos	_	_	_	_
35	muscle	_	NOUN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	HLA	_	PROPN	_	Number=Sing	_	_	_	_
9	class	_	NOUN	_	Number=Sing	_	_	_	_
10	I	_	PRON	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	mediated	_	VERB	_	Degree=Pos	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
17	correlates	_	VERB	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	Rb	_	NOUN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	line	_	NOUN	_	Number=Sing	_	_	_	_
29	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
30	as	_	ADV	_	_	_	_	_	_
31	well	_	ADV	_	Degree=Pos	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	human	_	ADJ	_	Degree=Pos	_	_	_	_
34	aortic	_	ADJ	_	Degree=Pos	_	_	_	_
35	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	HLA	_	PROPN	_	Number=Sing	_	_	_	_
2	class	_	NOUN	_	Number=Sing	_	_	_	_
3	I	_	PRON	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	mediated	_	VERB	_	Degree=Pos	_	_	_	_
6	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Rb	_	PROPN	_	Number=Sing	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	specifically	_	ADV	_	_	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	neutralizing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	Abs	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	basic	_	ADJ	_	Degree=Pos	_	_	_	_
18	fibroblast	_	NOUN	_	Degree=Pos	_	_	_	_
19	growth	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	bFGF	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	role	_	NOUN	_	Number=Sing	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	FGF	_	NOUN	_	Number=Sing	_	_	_	_
30	receptors	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	signaling	_	NOUN	_	Number=Sing	_	_	_	_
34	process	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
2	through	_	ADP	_	_	_	_	_	_
3	HLA	_	PROPN	_	Number=Sing	_	_	_	_
4	class	_	NOUN	_	Number=Sing	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	molecules	_	VERB	_	Number=Plur	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
9	E	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	within	_	ADP	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	h	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	quiescent	_	ADJ	_	Degree=Pos	_	_	_	_
19	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	Rb	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	cdk2	_	NOUN	_	Number=Sing	_	_	_	_
3	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	Olomoucine	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	as	_	ADV	_	_	_	_	_	_
8	well	_	ADV	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	negative	_	ADJ	_	Degree=Pos	_	_	_	_
14	cdk2	_	NOUN	_	Number=Sing	_	_	_	_
15	construct	_	NOUN	_	Number=Sing	_	_	_	_
16	prevented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	HLA	_	PROPN	_	Number=Sing	_	_	_	_
18	class	_	NOUN	_	Number=Sing	_	_	_	_
19	I	_	PRON	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	VERB	_	Degree=Pos	_	_	_	_
22	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	Rb	_	NOUN	_	Number=Sing	_	_	_	_
25	;	_	PUNCT	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	contrast	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	negative	_	ADJ	_	Degree=Pos	_	_	_	_
32	cdk4	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	cdk6	_	NOUN	_	Degree=Pos	_	_	_	_
35	constructs	_	NOUN	_	Number=Plur	_	_	_	_
36	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	no	_	DET	_	_	_	_	_	_
38	effect	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	there	_	PRON	_	_	_	_	_	_
4	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	no	_	DET	_	_	_	_	_	_
6	increase	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	cyclin	_	PROPN	_	Number=Sing	_	_	_	_
9	D	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	upon	_	ADP	_	_	_	_	_	_
15	HLA	_	PROPN	_	Number=Sing	_	_	_	_
16	class	_	NOUN	_	Number=Sing	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	ligation	_	VERB	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
23	E	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	kinase	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	Rb	_	NOUN	_	Number=Sing	_	_	_	_
30	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	E2F	_	NOUN	_	Number=Sing	_	_	_	_
35	activation	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003746	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	conserved	_	VERB	_	Degree=Pos	_	_	_	_
3	motif	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	promoters	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	several	_	ADJ	_	Degree=Pos	_	_	_	_
9	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	Th2	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	type	_	NOUN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	recently	_	ADV	_	_	_	_	_	_
4	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	novel	_	NOUN	_	Number=Sing	_	_	_	_
7	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	motif	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	promoters	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	several	_	ADJ	_	Degree=Pos	_	_	_	_
14	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
18	[	_	PUNCT	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	-	_	SYM	_	_	_	_	_	_
25	4	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	-5	_	NUM	_	NumType=Card	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	-	_	SYM	_	_	_	_	_	_
30	13	_	NUM	_	NumType=Card	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	human	_	ADJ	_	Degree=Pos	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	mouse	_	NOUN	_	Number=Sing	_	_	_	_
35	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	colony	_	NOUN	_	Number=Sing	_	_	_	_
40	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
41	factor	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	GM	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	CSF	_	PROPN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	]	_	PUNCT	_	_	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	core	_	NOUN	_	Number=Sing	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	CTTGG	_	NOUN	_	Number=Sing	_	_	_	_
7	...	_	PUNCT	_	_	_	_	_	_
8	CCAAG	_	NOUN	_	Number=Sing	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	present	_	ADJ	_	Degree=Pos	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	part	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	larger	_	ADJ	_	Degree=Cmp	_	_	_	_
16	palindromic	_	ADJ	_	Degree=Pos	_	_	_	_
17	sequences	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	each	_	DET	_	_	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
5	may	_	AUX	_	VerbForm=Fin	_	_	_	_
6	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	new	_	ADJ	_	Degree=Pos	_	_	_	_
10	family	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	trans	_	NOUN	_	Number=Plur	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	acting	_	VERB	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	assays	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	GM	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	CSF	_	PROPN	_	Number=Sing	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	strong	_	ADJ	_	Degree=Pos	_	_	_	_
14	positive	_	ADJ	_	Degree=Pos	_	_	_	_
15	effect	_	NOUN	_	Number=Sing	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	reporter	_	NOUN	_	Number=Sing	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	line	_	NOUN	_	Number=Sing	_	_	_	_
29	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_

1	J6	_	PROPN	_	Number=Sing	_	_	_	_
2	upon	_	ADP	_	_	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	sequence	_	NOUN	_	Number=Sing	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	give	_	VERB	_	VerbForm=Inf	_	_	_	_
11	either	_	CCONJ	_	_	_	_	_	_
12	six	_	NUM	_	NumType=Card	_	_	_	_
13	different	_	ADJ	_	Degree=Pos	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	bands	_	NOUN	_	Number=Plur	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	competed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	out	_	ADP	_	_	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	different	_	ADJ	_	Degree=Pos	_	_	_	_
22	parts	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	sequence	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	one	_	NUM	_	NumType=Card	_	_	_	_
28	specific	_	ADJ	_	Degree=Pos	_	_	_	_
29	band	_	NOUN	_	Number=Sing	_	_	_	_
30	which	_	PRON	_	PronType=Rel	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	competed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	out	_	ADP	_	_	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	each	_	DET	_	_	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	inverted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	repeats	_	NOUN	_	Number=Plur	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	depending	_	VERB	_	VerbForm=Ger	_	_	_	_
42	on	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	reconstitution	_	NOUN	_	Number=Sing	_	_	_	_
45	conditions	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	different	_	ADJ	_	Degree=Pos	_	_	_	_
3	genes	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	core	_	NOUN	_	Number=Sing	_	_	_	_
7	sequences	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	separated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	integer	_	ADJ	_	Degree=Pos	_	_	_	_
12	numbers	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	helical	_	ADJ	_	Degree=Pos	_	_	_	_
15	turns	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Considering	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	strong	_	ADJ	_	Degree=Pos	_	_	_	_
4	positive	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	presence	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	several	_	ADJ	_	Degree=Pos	_	_	_	_
15	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	may	_	AUX	_	VerbForm=Fin	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	coordinated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
31	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	T	_	PROPN	_	Number=Sing	_	_	_	_
34	helper	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003751	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	viruses	_	NOUN	_	Number=Plur	_	_	_	_
4	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	promoters	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	replication	_	NOUN	_	Number=Sing	_	_	_	_
11	competent	_	ADJ	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	exhibit	_	VERB	_	Degree=Pos	_	_	_	_
14	different	_	ADJ	_	Degree=Pos	_	_	_	_
15	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	tropisms	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	long	_	ADJ	_	Degree=Pos	_	_	_	_
11	terminal	_	NOUN	_	Number=Sing	_	_	_	_
12	repeat	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	LTR	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	constitutively	_	ADV	_	_	_	_	_	_
33	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	both	_	DET	_	_	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	which	_	PRON	_	PronType=Rel	_	_	_	_
41	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
42	highly	_	ADV	_	_	_	_	_	_
43	conserved	_	ADJ	_	Degree=Pos	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	HIV	_	NOUN	_	Number=Sing	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	simian	_	ADJ	_	Degree=Pos	_	_	_	_
48	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
49	virus	_	NOUN	_	Number=Sing	_	_	_	_
50	isolates	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	delineate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	motifs	_	NOUN	_	Number=Plur	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	replicative	_	ADJ	_	Degree=Pos	_	_	_	_
11	capacity	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	explore	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	possibility	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	SCONJ	_	_	_	_	_	_
20	extending	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	virus	_	NOUN	_	Number=Sing	_	_	_	_
23	host	_	NOUN	_	Number=Sing	_	_	_	_
24	range	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
28	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	promoters	_	NOUN	_	Number=Plur	_	_	_	_
31	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	inserted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	into	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	HIV	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	LTR	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	place	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	NF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kappa	_	NOUN	_	Number=Sing	_	_	_	_
46	B	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
49	binding	_	NOUN	_	Number=Sing	_	_	_	_
50	sites	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	substitutions	_	NOUN	_	Number=Plur	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	viral	_	ADJ	_	Degree=Pos	_	_	_	_
8	replication	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	infection	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
20	blood	_	NOUN	_	Number=Sing	_	_	_	_
21	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	continuous	_	ADJ	_	Degree=Pos	_	_	_	_
24	T-leukemia	_	PROPN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	lines	_	NOUN	_	Number=Plur	_	_	_	_
27	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	HIVs	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	which	_	PRON	_	PronType=Rel	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	plus	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
15	TATA	_	PROPN	_	Number=Sing	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	replaced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	promoters	_	NOUN	_	Number=Plur	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	also	_	ADV	_	_	_	_	_	_
26	constructed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Viruses	_	NOUN	_	Number=Plur	_	_	_	_
2	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	cytomegalovirus	_	NOUN	_	Number=Sing	_	_	_	_
6	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	early	_	ADJ	_	Degree=Pos	_	_	_	_
9	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
10	exhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	infectious	_	ADJ	_	Degree=Pos	_	_	_	_
12	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
13	similar	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	wild	_	ADJ	_	Degree=Pos	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	type	_	NOUN	_	Number=Sing	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
25	blood	_	NOUN	_	Number=Sing	_	_	_	_
26	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	AA2	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	but	_	CCONJ	_	_	_	_	_	_
31	replicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	less	_	ADV	_	Degree=Cmp	_	_	_	_
33	efficiently	_	ADV	_	_	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	H9	_	PROPN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	CEM	_	PROPN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	elements	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	capable	_	ADJ	_	Degree=Pos	_	_	_	_
10	of	_	SCONJ	_	_	_	_	_	_
11	restoring	_	VERB	_	VerbForm=Ger	_	_	_	_

1	Tat	_	NOUN	_	_	_	_	_	_
2	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	LTR	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	context	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	SCONJ	_	_	_	_	_	_
11	directing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	reporter	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	as	_	ADV	_	_	_	_	_	_
16	well	_	ADV	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	production	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	infectious	_	ADJ	_	Degree=Pos	_	_	_	_
23	progeny	_	NOUN	_	Number=Sing	_	_	_	_
24	virions	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003752	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Naive	_	ADJ	_	Degree=Pos	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	CD45RA	_	NOUN	_	Number=Sing	_	_	_	_
4	+	_	SYM	_	_	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	more	_	ADV	_	_	_	_	_	_
5	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
8	stress	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	signals	_	NOUN	_	Number=Plur	_	_	_	_
12	than	_	ADP	_	_	_	_	_	_
13	memory	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	CD45RO	_	NOUN	_	Number=Sing	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Formation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
4	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
5	intermediates	_	NOUN	_	Number=Plur	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	ROI	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	after	_	SCONJ	_	_	_	_	_	_
10	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
11	stress	_	NOUN	_	Number=Sing	_	_	_	_
12	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	signal	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	e.g.	_	X	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
33	receptor	_	NOUN	_	Number=Sing	_	_	_	_
34	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	ROI	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	large	_	ADJ	_	Degree=Pos	_	_	_	_
11	extent	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	attributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Now	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	whether	_	SCONJ	_	_	_	_	_	_
6	naive	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	memory	_	NOUN	_	Number=Sing	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	ROI	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	mediated	_	VERB	_	Degree=Pos	_	_	_	_
19	signals	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	CD45RA	_	PROPN	_	Number=Sing	_	_	_	_
3	+	_	SYM	_	_	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	naive	_	ADJ	_	Degree=Pos	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	CD45RO	_	NOUN	_	Number=Sing	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	memory	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	directly	_	ADV	_	_	_	_	_	_
17	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	translocation	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	stronger	_	ADJ	_	Degree=Cmp	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	naive	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	than	_	ADP	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	memory	_	NOUN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
37	could	_	AUX	_	VerbForm=Fin	_	_	_	_
38	be	_	AUX	_	VerbForm=Inf	_	_	_	_
39	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
42	doses	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	composition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	NF	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	p50	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	RelA	_	NOUN	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	similar	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	types	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	ROI	_	NOUN	_	Number=Sing	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	similar	_	ADJ	_	Degree=Pos	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	there	_	PRON	_	_	_	_	_	_
14	were	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	no	_	DET	_	_	_	_	_	_
16	differences	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	ROI	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
21	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	antioxidative	_	ADJ	_	Degree=Pos	_	_	_	_
24	capacities	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	probable	_	ADJ	_	Degree=Pos	_	_	_	_
3	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	point	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
8	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
9	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
10	:	_	PUNCT	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	CD45RA	_	NOUN	_	Number=Sing	_	_	_	_
13	+	_	SYM	_	_	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_

1	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
2	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	more	_	ADV	_	_	_	_	_	_
5	profound	_	ADJ	_	Degree=Pos	_	_	_	_
6	depression	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	representing	_	VERB	_	VerbForm=Ger	_	_	_	_
8	different	_	ADJ	_	Degree=Pos	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	stages	_	NOUN	_	Number=Plur	_	_	_	_
15	can	_	AUX	_	VerbForm=Fin	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	differentially	_	ADV	_	_	_	_	_	_
18	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	ROI	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
23	signals	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003755	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	AP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	mediate	_	ADJ	_	Degree=Pos	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	acid	_	ADJ	_	Degree=Pos	_	_	_	_
12	sphingomyelinase	_	NOUN	_	Number=Sing	_	_	_	_
13	during	_	ADP	_	_	_	_	_	_
14	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Cells	_	NOUN	_	Number=Plur	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
6	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	line	_	NOUN	_	Number=Sing	_	_	_	_
9	THP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	differentiate	_	NOUN	_	Number=Sing	_	_	_	_
13	towards	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	like	_	ADJ	_	Degree=Pos	_	_	_	_
18	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
19	when	_	ADV	_	PronType=Int	_	_	_	_
20	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
23	12	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	myristate	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	13	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	acetate	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	PMA	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	1,25	_	NUM	_	NumType=Card	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	dihydroxy-vitamin	_	NOUN	_	Number=Sing	_	_	_	_

1	D3	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	various	_	ADJ	_	Degree=Pos	_	_	_	_
5	other	_	ADJ	_	Degree=Pos	_	_	_	_
6	agents	_	NOUN	_	Number=Plur	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	lysosomal	_	ADJ	_	Degree=Pos	_	_	_	_
10	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
11	acid	_	ADJ	_	Number=Sing	_	_	_	_
12	sphingomyelinase	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	ASM	_	NOUN	_	Number=Sing	_	_	_	_
15	;	_	PUNCT	_	_	_	_	_	_
16	E.C.3.1.4.12	_	NUM	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	during	_	ADP	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	process	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	strongly	_	ADV	_	_	_	_	_	_
26	elevated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
29	THP	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	as	_	ADV	_	_	_	_	_	_
35	well	_	ADV	_	Degree=Pos	_	_	_	_
36	as	_	ADP	_	_	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	differentiated	_	ADJ	_	Degree=Pos	_	_	_	_
39	human	_	ADJ	_	Degree=Pos	_	_	_	_
40	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
41	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
3	blotting	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	RNase	_	PROPN	_	Number=Sing	_	_	_	_
6	protection	_	NOUN	_	Number=Sing	_	_	_	_
7	assay	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	run	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	analyses	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	up	_	ADP	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	regulation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	ASM	_	PROPN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	mainly	_	ADV	_	_	_	_	_	_
29	at	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	level	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	that	_	DET	_	_	_	_	_	_
36	new	_	ADJ	_	Degree=Pos	_	_	_	_
37	protein	_	NOUN	_	Number=Sing	_	_	_	_
38	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
39	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	ASM	_	NOUN	_	Number=Sing	_	_	_	_
44	activity	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	PMA	_	PROPN	_	Number=Sing	_	_	_	_
9	treatment	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	further	_	ADV	_	_	_	_	_	_
12	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	respect	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	control	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	series	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	5	_	NUM	_	NumType=Card	_	_	_	_
5	'	_	NOUN	_	_	_	_	_	_
6	deletion	_	NOUN	_	Number=Sing	_	_	_	_
7	derivatives	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	transient	_	ADJ	_	Degree=Pos	_	_	_	_
17	transfection	_	NOUN	_	Number=Sing	_	_	_	_
18	assays	_	NOUN	_	Number=Plur	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	elements	_	NOUN	_	Number=Plur	_	_	_	_
23	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	basal	_	ADJ	_	Degree=Pos	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	PMA	_	PROPN	_	Number=Sing	_	_	_	_
3	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
4	element	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	319	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	219	_	NUM	_	NumType=Card	_	_	_	_
16	bp	_	NOUN	_	Number=Sing	_	_	_	_
17	upstream	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	initiation	_	NOUN	_	Number=Sing	_	_	_	_
21	codon	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	co	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	transfections	_	NOUN	_	Number=Plur	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	AP	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
37	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	ASM	_	NOUN	_	Number=Sing	_	_	_	_
41	promoter	_	NOUN	_	Number=Sing	_	_	_	_
42	activity	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	which	_	PRON	_	PronType=Rel	_	_	_	_
45	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
46	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
47	when	_	ADV	_	PronType=Int	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	binding	_	NOUN	_	Number=Sing	_	_	_	_
50	sites	_	NOUN	_	Number=Plur	_	_	_	_
51	for	_	ADP	_	_	_	_	_	_
52	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
53	two	_	NUM	_	NumType=Card	_	_	_	_
54	factors	_	NOUN	_	Number=Plur	_	_	_	_
55	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
56	deleted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	supershift	_	NOUN	_	Number=Sing	_	_	_	_
8	assays	_	NOUN	_	Number=Plur	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	specifically	_	ADV	_	_	_	_	_	_
16	bound	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	present	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	extracts	_	NOUN	_	Number=Plur	_	_	_	_
8	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	both	_	DET	_	_	_	_	_	_
11	induced	_	VERB	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	uninduced	_	ADJ	_	Degree=Pos	_	_	_	_
14	THP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	intensity	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	complex	_	NOUN	_	Number=Sing	_	_	_	_
8	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
12	when	_	ADV	_	PronType=Int	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	extracts	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	PMA	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	From	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	concerted	_	ADJ	_	Degree=Pos	_	_	_	_
10	action	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	essential	_	ADJ	_	Degree=Pos	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	up	_	ADJ	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	regulation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	ASM	_	PROPN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	during	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	process	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
35	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003757	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
2	hormone	_	NOUN	_	Number=Sing	_	_	_	_
3	suppression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	cytostasis	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	effect	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
13	hormones	_	NOUN	_	Number=Plur	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
18	tumor	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	cytostasis	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	hydrocortisone	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
28	hormone	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	Dex	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	cytostasis	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	presence	_	NOUN	_	Number=Sing	_	_	_	_
40	or	_	CCONJ	_	_	_	_	_	_
41	absence	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	tumor	_	NOUN	_	Number=Sing	_	_	_	_
44	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
45	factor	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	alpha	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Dex	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	completely	_	ADV	_	_	_	_	_	_
7	reversed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	RU38486	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	clarify	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	underlying	_	ADJ	_	Degree=Pos	_	_	_	_
5	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	effects	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Dex	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	avidity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	beta2	_	NOUN	_	Number=Sing	_	_	_	_
18	integrin	_	NOUN	_	Number=Sing	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	neutrophil	_	NOUN	_	Degree=Pos	_	_	_	_
22	surface	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	how	_	ADV	_	PronType=Int	_	_	_	_
25	these	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
26	might	_	AUX	_	VerbForm=Fin	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	turn	_	VERB	_	VerbForm=Inf	_	_	_	_
29	affect	_	VERB	_	Number=Sing	_	_	_	_
30	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	tumor	_	NOUN	_	Number=Sing	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	binding	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Dex	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	neutrophil	_	NOUN	_	Degree=Pos	_	_	_	_
8	properties	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	RU38486	_	PROPN	_	Number=Sing	_	_	_	_
12	completely	_	ADV	_	_	_	_	_	_
13	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	forms	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Dex	_	NOUN	_	Number=Sing	_	_	_	_
18	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	findings	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
9	hormone	_	NOUN	_	Number=Sing	_	_	_	_
10	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	neutrophil	_	ADJ	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
15	tumor	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	cytostasis	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	at	_	ADV	_	_	_	_	_	_
20	least	_	ADV	_	Degree=Sup	_	_	_	_
21	partially	_	ADV	_	_	_	_	_	_
22	due	_	ADP	_	_	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	lowering	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	ligand	_	NOUN	_	Number=Sing	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	avidity	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	beta2	_	NOUN	_	Number=Sing	_	_	_	_
33	integrin	_	NOUN	_	Number=Sing	_	_	_	_
34	on	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	neutrophil	_	NOUN	_	Degree=Pos	_	_	_	_
37	surface	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003759	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
6	molecule	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	low	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	density	_	NOUN	_	Number=Sing	_	_	_	_
13	lipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Low	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	density	_	NOUN	_	Number=Sing	_	_	_	_
4	lipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	LDL	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	well	_	ADV	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	risk	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	incubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	lipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	pathophysiologic	_	ADJ	_	Degree=Pos	_	_	_	_
11	amounts	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Among	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	documented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	responses	_	NOUN	_	Number=Plur	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	LDL	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	play	_	VERB	_	VerbForm=Inf	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	major	_	ADJ	_	Degree=Pos	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	SCONJ	_	_	_	_	_	_
23	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	intimal	_	ADJ	_	Degree=Pos	_	_	_	_
25	plaque	_	NOUN	_	Number=Sing	_	_	_	_
26	formation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	presented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	here	_	ADV	_	PronType=Dem	_	_	_	_
5	link	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	atheogenic	_	ADJ	_	Degree=Pos	_	_	_	_
8	lipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	LDL	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
18	molecule	_	NOUN	_	Number=Sing	_	_	_	_
19	important	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	atherogenesis	_	ADJ	_	Number=Sing	_	_	_	_
22	Human	_	ADJ	_	Degree=Pos	_	_	_	_
23	LDL	_	PROPN	_	Number=Sing	_	_	_	_
24	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
29	molecule	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	transcriptionally	_	ADV	_	_	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	increase	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
43	levels	_	NOUN	_	Number=Plur	_	_	_	_
44	through	_	ADP	_	_	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
49	promoter	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	anti-VCAM	_	ADJ	_	Degree=Pos	_	_	_	_
7	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	day	_	NOUN	_	Number=Sing	_	_	_	_
6	incubation	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	LDL	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	PROPN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	key	_	ADJ	_	Degree=Pos	_	_	_	_
25	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	stress	_	NOUN	_	Number=Sing	_	_	_	_
28	sensor	_	NOUN	_	Number=Sing	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	VCAM	_	ADJ	_	Number=Sing	_	_	_	_
31	regulation	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	at	_	ADP	_	_	_	_	_	_
35	basal	_	ADJ	_	Degree=Pos	_	_	_	_
36	level	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	activities	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	AP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	GATA	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	other	_	ADJ	_	Degree=Pos	_	_	_	_
17	hand	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	LDL	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	component	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	LDL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
10	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	attributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	through	_	ADP	_	_	_	_	_	_
27	AP	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	GATA	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	LDL	_	PROPN	_	Number=Sing	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	inducer	_	NOUN	_	Number=Sing	_	_	_	_
10	possibly	_	ADV	_	_	_	_	_	_
11	distinct	_	VERB	_	Number=Sing	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003760	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	p38	_	NUM	_	Number=Sing	_	_	_	_
2	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	mediates	_	VERB	_	Number=Plur	_	_	_	_
8	signal	_	NOUN	_	Number=Sing	_	_	_	_
9	integration	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	TCR	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	CD28	_	NOUN	_	Number=Sing	_	_	_	_
14	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	primary	_	ADJ	_	Degree=Pos	_	_	_	_
17	murine	_	NOUN	_	Number=Sing	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Optimal	_	ADJ	_	Degree=Pos	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	signals	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	one	_	NUM	_	NumType=Card	_	_	_	_
10	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	TCR	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	another	_	DET	_	_	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	CD28	_	PROPN	_	Number=Sing	_	_	_	_
18	costimulatory	_	ADJ	_	Number=Sing	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	primary	_	ADJ	_	Degree=Pos	_	_	_	_
24	mouse	_	NOUN	_	Number=Sing	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
5	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	p38	_	NOUN	_	Number=Sing	_	_	_	_
16	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	but	_	CCONJ	_	_	_	_	_	_
19	not	_	ADV	_	_	_	_	_	_
20	Jun	_	PROPN	_	Number=Sing	_	_	_	_
21	NH2	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	terminal	_	NOUN	_	Number=Sing	_	_	_	_
24	kinase	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	JNK	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	weakly	_	ADV	_	_	_	_	_	_
31	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	upon	_	ADP	_	_	_	_	_	_
33	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	either	_	CCONJ	_	_	_	_	_	_
36	anti-CD3	_	NOUN	_	Number=Sing	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	anti-CD28	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	murine	_	NOUN	_	Number=Sing	_	_	_	_
41	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	splenic	_	ADJ	_	Degree=Pos	_	_	_	_
44	T	_	NOUN	_	Number=Sing	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	p38	_	PROPN	_	Number=Sing	_	_	_	_
4	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	strongly	_	ADV	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	synergistically	_	ADV	_	_	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	either	_	CCONJ	_	_	_	_	_	_
12	CD3	_	PROPN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	CD28	_	PROPN	_	Number=Sing	_	_	_	_
15	coligation	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	PMA	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_
21	ionophore	_	ADJ	_	Number=Sing	_	_	_	_
22	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	mimics	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	TCR	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	CD3	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	CD28-mediated	_	PROPN	_	Number=Sing	_	_	_	_
31	signaling	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	p38	_	NOUN	_	Number=Sing	_	_	_	_
4	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
5	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	closely	_	ADV	_	_	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	PMA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	JNK	_	PROPN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
13	+	_	SYM	_	_	_	_	_	_
14	ionophore	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	T	_	NUM	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	production	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IFN	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	gamma	_	NOUN	_	Number=Sing	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	both	_	CCONJ	_	_	_	_	_	_
22	CD3	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	CD3	_	PROPN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	CD28	_	PROPN	_	Number=Sing	_	_	_	_
27	ligation	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	ATF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	proteins	_	NOUN	_	Number=Plur	_	_	_	_
40	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
41	each	_	DET	_	_	_	_	_	_
42	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	p38	_	PROPN	_	Number=Sing	_	_	_	_
46	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
47	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
48	SB203580	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	p38	_	NOUN	_	Number=Sing	_	_	_	_
6	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
7	1	_	NUM	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	important	_	ADJ	_	Degree=Pos	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	signal	_	ADJ	_	Number=Sing	_	_	_	_
15	integration	_	NOUN	_	Number=Sing	_	_	_	_
16	during	_	ADP	_	_	_	_	_	_
17	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	primary	_	ADJ	_	Degree=Pos	_	_	_	_
20	mouse	_	NOUN	_	Number=Sing	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	2	_	X	_	_	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	may	_	AUX	_	VerbForm=Fin	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	involved	_	ADJ	_	Degree=Pos	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	induction	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	c	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	Jun	_	PROPN	_	Number=Sing	_	_	_	_
36	activation	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	augmentation	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	AP	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
44	activity	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	3	_	NUM	_	_	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
50	whether	_	SCONJ	_	_	_	_	_	_
51	T	_	PROPN	_	Number=Sing	_	_	_	_
52	cells	_	NOUN	_	Number=Plur	_	_	_	_
53	enter	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
54	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
55	state	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	functional	_	ADJ	_	Degree=Pos	_	_	_	_
58	unresponsiveness	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003761	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	p65	_	PROPN	_	Number=Sing	_	_	_	_
3	subunit	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	kappa	_	VERB	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	two	_	NUM	_	NumType=Card	_	_	_	_
15	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
16	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	generally	_	ADV	_	_	_	_	_	_
12	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
19	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
20	kappa	_	VERB	_	Number=Sing	_	_	_	_
21	B.	_	PROPN	_	Number=Sing	_	_	_	_
22	Overproduced	_	VERB	_	_	_	_	_	_
23	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
24	kappa	_	VERB	_	Number=Sing	_	_	_	_
25	B	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	free	_	ADJ	_	Degree=Pos	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	PROPN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	rapidly	_	ADV	_	_	_	_	_	_
36	degraded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	p65	_	NOUN	_	Number=Sing	_	_	_	_
4	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	kappa	_	VERB	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	stabilization	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
27	kappa	_	VERB	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	p65	_	PROPN	_	Number=Sing	_	_	_	_
5	delta	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	naturally	_	ADV	_	_	_	_	_	_
9	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
10	splice	_	NOUN	_	Number=Sing	_	_	_	_
11	variant	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	fails	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	markedly	_	ADV	_	_	_	_	_	_
16	augment	_	VERB	_	VerbForm=Inf	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	levels	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
3	p65	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	coexpressed	_	VERB	_	Degree=Pos	_	_	_	_
6	p50	_	NOUN	_	Number=Sing	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	whereas	_	SCONJ	_	_	_	_	_	_
11	p65	_	NUM	_	Number=Sing	_	_	_	_
12	delta	_	PROPN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	partly	_	ADV	_	_	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	PROPN	_	Number=Sing	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	p65	_	NOUN	_	Number=Sing	_	_	_	_
26	can	_	AUX	_	VerbForm=Fin	_	_	_	_
27	maintain	_	VERB	_	VerbForm=Inf	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	p65	_	NUM	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	kappa	_	VERB	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	loop	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	ensuring	_	VERB	_	VerbForm=Ger	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	PROPN	_	Number=Sing	_	_	_	_
20	B	_	PROPN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	held	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
26	until	_	SCONJ	_	_	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	specifically	_	ADV	_	_	_	_	_	_
30	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	translocate	_	VERB	_	VerbForm=Inf	_	_	_	_
33	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003763	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
3	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
6	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	down	_	ADV	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	major	_	ADJ	_	Degree=Pos	_	_	_	_
13	depression	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Some	_	DET	_	_	_	_	_	_
2	patients	_	NOUN	_	Number=Plur	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	major	_	ADJ	_	Degree=Pos	_	_	_	_
5	depressive	_	ADJ	_	Degree=Pos	_	_	_	_
6	disorder	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	MDD	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	plasma	_	NOUN	_	Number=Sing	_	_	_	_
13	cortisol	_	NOUN	_	Number=Sing	_	_	_	_
14	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	show	_	VERB	_	VerbForm=Inf	_	_	_	_
17	failure	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
20	cortisol	_	ADJ	_	Degree=Pos	_	_	_	_
21	secretion	_	NOUN	_	Number=Sing	_	_	_	_
22	upon	_	ADP	_	_	_	_	_	_
23	administration	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	DEX	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	yet	_	CCONJ	_	_	_	_	_	_
31	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
32	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	not	_	PART	_	_	_	_	_	_
34	have	_	VERB	_	VerbForm=Inf	_	_	_	_
35	Cushingoid	_	NOUN	_	Degree=Pos	_	_	_	_
36	features	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	study	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
5	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	GC	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	resistance	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	[	_	PUNCT	_	_	_	_	_	_
13	3H	_	X	_	Number=Sing	_	_	_	_
14	]	_	PUNCT	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	DEX	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	assays	_	NOUN	_	Number=Plur	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	measure	_	VERB	_	VerbForm=Inf	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vitro	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	GC	_	NOUN	_	Number=Sing	_	_	_	_
30	receptor	_	NOUN	_	Number=Sing	_	_	_	_
31	affinity	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	Kd	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	number	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	Bmax	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
44	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	11	_	NUM	_	NumType=Card	_	_	_	_
47	MDD	_	NOUN	_	Number=Sing	_	_	_	_
48	patients	_	NOUN	_	Number=Plur	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	15	_	NUM	_	NumType=Card	_	_	_	_
51	control	_	NOUN	_	Number=Sing	_	_	_	_
52	subjects	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	MDD	_	NOUN	_	Number=Sing	_	_	_	_
9	group	_	NOUN	_	Number=Sing	_	_	_	_
10	;	_	PUNCT	_	_	_	_	_	_
11	thus	_	ADV	_	_	_	_	_	_
12	any	_	DET	_	_	_	_	_	_
13	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
14	defect	_	NOUN	_	Number=Sing	_	_	_	_
15	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	lack	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	GC	_	PROPN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	MDD	_	NOUN	_	Number=Sing	_	_	_	_
26	patients	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	if	_	SCONJ	_	_	_	_	_	_
29	present	_	ADJ	_	Degree=Pos	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	probably	_	ADV	_	_	_	_	_	_
32	lies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	beyond	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	initial	_	ADJ	_	Degree=Pos	_	_	_	_
36	receptor	_	NOUN	_	Number=Sing	_	_	_	_
37	binding	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	DEX	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	1.0	_	NUM	_	NumType=Card	_	_	_	_
4	mg	_	NUM	_	Number=Sing	_	_	_	_
5	orally	_	ADV	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	administered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	study	_	VERB	_	VerbForm=Inf	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	vivo	_	PROPN	_	Number=Sing	_	_	_	_
13	GC	_	NOUN	_	Number=Sing	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	down	_	ADP	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	control	_	NOUN	_	Number=Sing	_	_	_	_
5	group	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	fewer	_	ADJ	_	Degree=Cmp	_	_	_	_
8	depressed	_	ADJ	_	Degree=Pos	_	_	_	_
9	subjects	_	NOUN	_	Number=Plur	_	_	_	_
10	down	_	ADV	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	Bmax	_	NOUN	_	Number=Sing	_	_	_	_
14	after	_	ADP	_	_	_	_	_	_
15	DEX	_	PROPN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	paired	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	t-test	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	Bmax	_	PROPN	_	Number=Sing	_	_	_	_
6	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	significantly	_	ADV	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	control	_	NOUN	_	Number=Sing	_	_	_	_
11	group	_	NOUN	_	Number=Sing	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	depressed	_	ADJ	_	Degree=Pos	_	_	_	_
17	group	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Receptor	_	NOUN	_	Number=Sing	_	_	_	_
2	number	_	NOUN	_	Number=Sing	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	control	_	NOUN	_	Number=Sing	_	_	_	_
6	day	_	NOUN	_	Number=Sing	_	_	_	_
7	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	correlate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	significantly	_	ADV	_	_	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	degree	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	down	_	ADP	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	regulation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	severity	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	depression	_	NOUN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	cortisol	_	ADJ	_	Number=Sing	_	_	_	_
25	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
26	across	_	ADP	_	_	_	_	_	_
27	all	_	DET	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	subjects	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	lend	_	VERB	_	VerbForm=Inf	_	_	_	_
6	support	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	previous	_	ADJ	_	Degree=Pos	_	_	_	_
9	reports	_	NOUN	_	Number=Plur	_	_	_	_
10	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	GC	_	PROPN	_	Number=Sing	_	_	_	_
13	resistance	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	MDD	_	NOUN	_	Number=Sing	_	_	_	_
16	results	_	NOUN	_	Number=Plur	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	GC	_	NOUN	_	Number=Sing	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	binding	_	VERB	_	Number=Sing	_	_	_	_
23	abnormality	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
27	emphasize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	importance	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	SCONJ	_	_	_	_	_	_
31	considering	_	VERB	_	VerbForm=Ger	_	_	_	_
32	receptor	_	NOUN	_	Number=Sing	_	_	_	_
33	studies	_	NOUN	_	Number=Plur	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	context	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	GC	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	processes	_	NOUN	_	Number=Plur	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	order	_	NOUN	_	Number=Sing	_	_	_	_
45	to	_	PART	_	_	_	_	_	_
46	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	exact	_	ADJ	_	Degree=Pos	_	_	_	_
49	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
50	defect	_	NOUN	_	Number=Sing	_	_	_	_
51	(	_	PUNCT	_	_	_	_	_	_
52	s	_	X	_	_	_	_	_	_
53	)	_	PUNCT	_	_	_	_	_	_
54	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
55	to	_	ADP	_	_	_	_	_	_
56	GC	_	PROPN	_	Number=Sing	_	_	_	_
57	resistance	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003765	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cutting	_	VERB	_	VerbForm=Ger	_	_	_	_
2	edge	_	NOUN	_	Number=Sing	_	_	_	_
3	:	_	PUNCT	_	_	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	NF	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
14	:	_	PUNCT	_	_	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	4	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	5	_	NUM	_	NumType=Card	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	AT1	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	AT4	_	PROPN	_	Number=Sing	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	cytoplasmically	_	ADV	_	_	_	_	_	_
14	in	_	SCONJ	_	_	_	_	_	_
15	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	whereas	_	SCONJ	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	AT2	_	PROPN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	AT3	_	PROPN	_	Number=Sing	_	_	_	_
26	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
29	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Likewise	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	AT1	_	PROPN	_	Number=Sing	_	_	_	_
6	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	AT4	_	PROPN	_	Number=Sing	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	SCONJ	_	_	_	_	_	_
16	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	levels	_	NOUN	_	Number=Plur	_	_	_	_
22	can	_	AUX	_	VerbForm=Fin	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	significantly	_	ADV	_	_	_	_	_	_
25	up	_	ADP	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	Th2	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	4	_	NUM	_	NumType=Card	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	IL	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	5	_	NUM	_	NumType=Card	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	AT	_	ADP	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	ATs	_	PROPN	_	Number=Plur	_	_	_	_
5	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nuclei	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	5	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Only	_	ADV	_	_	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	AT1	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	AT4	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	not	_	ADV	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	AT2	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	AT3	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	translocated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	into	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	4	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	5	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	delineate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	novel	_	NOUN	_	Number=Sing	_	_	_	_
6	pathway	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	network	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	"	_	PUNCT	_	_	_	_	_	_
16	control	_	VERB	_	Number=Sing	_	_	_	_
17	"	_	PUNCT	_	_	_	_	_	_
18	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
19	via	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	release	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	4	_	NUM	_	NumType=Card	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	5	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	AT	_	ADP	_	_	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	later	_	ADJ	_	Degree=Cmp	_	_	_	_
8	feedback	_	NOUN	_	Number=Sing	_	_	_	_
9	"	_	PUNCT	_	_	_	_	_	_
10	talking	_	NOUN	_	Number=Sing	_	_	_	_
11	"	_	PUNCT	_	_	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	exist	_	VERB	_	VerbForm=Inf	_	_	_	_
14	between	_	ADP	_	_	_	_	_	_
15	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003767	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Osteoclast	_	ADJ	_	Number=Sing	_	_	_	_
2	markers	_	NOUN	_	Number=Plur	_	_	_	_
3	accumulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	developing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
10	blood	_	NOUN	_	Number=Sing	_	_	_	_
11	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	precursors	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	osteoclasts	_	NOUN	_	Number=Plur	_	_	_	_
7	develop	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	vitro	_	NOUN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	;	_	PUNCT	_	_	_	_	_	_
14	however	_	ADV	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	special	_	ADJ	_	Degree=Pos	_	_	_	_
17	cultures	_	NOUN	_	Number=Plur	_	_	_	_
18	conditions	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
23	mobilized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
25	blood	_	NOUN	_	Number=Sing	_	_	_	_
26	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	apparently	_	ADV	_	_	_	_	_	_
28	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
8	osteoclast	_	ADJ	_	Degree=Pos	_	_	_	_
9	markers	_	NOUN	_	Number=Plur	_	_	_	_
10	differentiate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	precursors	_	NOUN	_	Number=Plur	_	_	_	_
13	present	_	VERB	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	nonmobilized	_	VERB	_	Degree=Pos	_	_	_	_
16	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
17	blood	_	NOUN	_	Number=Sing	_	_	_	_
18	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	without	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	addition	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	stromal	_	ADJ	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	growth	_	NOUN	_	Number=Sing	_	_	_	_
32	factors	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	steroids	_	NOUN	_	Number=Plur	_	_	_	_
37	;	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
40	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
41	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Three	_	NUM	_	NumType=Card	_	_	_	_
2	days	_	NOUN	_	Number=Plur	_	_	_	_
3	after	_	SCONJ	_	_	_	_	_	_
4	establishing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	high	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	density	_	NOUN	_	Number=Sing	_	_	_	_
8	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
9	cultures	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	1.5	_	NUM	_	NumType=Card	_	_	_	_
12	x	_	SYM	_	_	_	_	_	_
13	10	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	cm2	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	serum	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	medium	_	ADJ	_	Degree=Pos	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	small	_	ADJ	_	Degree=Pos	_	_	_	_
29	adherent	_	ADJ	_	Degree=Pos	_	_	_	_
30	colonies	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	tartrate	_	ADJ	_	Degree=Pos	_	_	_	_
33	resistant	_	NOUN	_	Number=Sing	_	_	_	_
34	acid	_	ADJ	_	Number=Sing	_	_	_	_
35	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
36	positive	_	ADJ	_	Degree=Pos	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	TRAP	_	NOUN	_	Number=Sing	_	_	_	_
39	+	_	SYM	_	_	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	emerge	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	amidst	_	VERB	_	_	_	_	_	_
45	massive	_	ADJ	_	Degree=Pos	_	_	_	_
46	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
47	cell	_	NOUN	_	Number=Sing	_	_	_	_
48	death	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	adherent	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	eccentrically	_	ADV	_	_	_	_	_	_
7	placed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	round	_	ADJ	_	Degree=Pos	_	_	_	_
10	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	express	_	VERB	_	Degree=Pos	_	_	_	_
14	low	_	ADJ	_	Degree=Pos	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	TRAP	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	sodium	_	NOUN	_	Number=Sing	_	_	_	_
20	fluoride	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	resistant	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	alpha-naphthyl-acetate	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	esterase	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	NaF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	R-NSE	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Over	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	next	_	ADJ	_	Degree=Pos	_	_	_	_
4	week	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	population	_	NOUN	_	Number=Sing	_	_	_	_
9	accumulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
11	markers	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	osteoclasts	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	vitronectin	_	NOUN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	[	_	PUNCT	_	_	_	_	_	_
18	VR	_	NOUN	_	Number=Sing	_	_	_	_
19	]	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	calcitonin	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	TRAP	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	cathepsin	_	NOUN	_	Number=Sing	_	_	_	_
27	K	_	PROPN	_	Number=Sing	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	nuclearity	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	covering	_	VERB	_	VerbForm=Ger	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	entire	_	ADJ	_	Degree=Pos	_	_	_	_
40	surface	_	NOUN	_	Number=Sing	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	15	_	NUM	_	NumType=Card	_	_	_	_
43	days	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	bone	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	VR	_	NOUN	_	Number=Sing	_	_	_	_
7	+	_	SYM	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	TRAP	_	NOUN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	low	_	ADJ	_	Degree=Pos	_	_	_	_
14	multinuclearity	_	NOUN	_	Number=Sing	_	_	_	_
15	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	cover	_	VERB	_	VerbForm=Inf	_	_	_	_
18	up	_	ADP	_	_	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	50	_	NUM	_	NumType=Card	_	_	_	_
21	%	_	SYM	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	surface	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Resorption	_	NOUN	_	Number=Sing	_	_	_	_
2	lacunae	_	NOUN	_	Number=Sing	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	day	_	NOUN	_	Number=Sing	_	_	_	_
8	22	_	NUM	_	NumType=Card	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	pits	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	nearly	_	ADV	_	_	_	_	_	_
7	as	_	ADV	_	_	_	_	_	_
8	numerous	_	ADJ	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	preosteoclast	_	ADJ	_	Degree=Pos	_	_	_	_
14	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
17	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	subset	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	osteoclast	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	like	_	ADJ	_	Degree=Pos	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	achieved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	osteoclastic	_	ADJ	_	Degree=Pos	_	_	_	_
33	maturity	_	NOUN	_	Number=Sing	_	_	_	_
34	under	_	ADP	_	_	_	_	_	_
35	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
36	culture	_	NOUN	_	Number=Sing	_	_	_	_
37	conditions	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Transcripts	_	NOUN	_	Number=Plur	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	osteoprotegerin	_	PROPN	_	Number=Sing	_	_	_	_
4	ligand	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	OPGL	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	osteoclast	_	ADJ	_	Degree=Pos	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	RANKL	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	TRANCE	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	likely	_	ADJ	_	Degree=Pos	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	adherent	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	adherent	_	ADJ	_	Degree=Pos	_	_	_	_
5	population	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	preosteoclast	_	ADJ	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	osteoclast	_	ADJ	_	Degree=Pos	_	_	_	_
13	phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
14	properties	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	arises	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	selectively	_	ADV	_	_	_	_	_	_
18	under	_	ADP	_	_	_	_	_	_
19	simple	_	ADJ	_	Degree=Pos	_	_	_	_
20	culture	_	NOUN	_	Number=Sing	_	_	_	_
21	conditions	_	NOUN	_	Number=Plur	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	normal	_	ADJ	_	Degree=Pos	_	_	_	_
24	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	characterization	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	should	_	AUX	_	VerbForm=Fin	_	_	_	_
7	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	involved	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	terminal	_	NOUN	_	Number=Sing	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	osteoclasts	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003768	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Mutual	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	activator	_	NOUN	_	Number=Sing	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
13	s	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	kappa	_	VERB	_	Number=Sing	_	_	_	_
18	B	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NK	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	complex	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	sequestered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	kappa	_	VERB	_	Number=Sing	_	_	_	_
20	B	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	PROPN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	MAD	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	3	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Various	_	ADJ	_	Degree=Pos	_	_	_	_
2	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
4	relieve	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
9	largely	_	ADV	_	_	_	_	_	_
10	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	localization	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	target	_	NOUN	_	Number=Sing	_	_	_	_
25	genes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	here	_	ADV	_	PronType=Dem	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	ADV	_	PronType=Rel	_	_	_	_
12	different	_	ADJ	_	Degree=Pos	_	_	_	_
13	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	including	_	VERB	_	VerbForm=Ger	_	_	_	_
16	tumor	_	NOUN	_	Number=Sing	_	_	_	_
17	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
22	12	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	myristate	_	NOUN	_	Number=Sing	_	_	_	_
25	13	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	acetate	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	cause	_	VERB	_	_	_	_	_	_
30	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
31	degradation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
34	kappa	_	VERB	_	Number=Sing	_	_	_	_
35	B	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	alpha	_	PROPN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
41	activation	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	NF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kappa	_	NOUN	_	Number=Sing	_	_	_	_
46	B	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	by	_	ADP	_	_	_	_	_	_
50	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
51	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
52	increase	_	NOUN	_	Number=Sing	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
55	kappa	_	VERB	_	Number=Sing	_	_	_	_
56	B	_	PROPN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	alpha	_	PROPN	_	Number=Sing	_	_	_	_
59	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
60	and	_	CCONJ	_	_	_	_	_	_
61	protein	_	VERB	_	Number=Sing	_	_	_	_
62	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	Transfection	_	NOUN	_	Number=Sing	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	kappa	_	VERB	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	PROPN	_	Number=Sing	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	potently	_	ADV	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	PROPN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	p65	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	model	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	kappa	_	VERB	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	mutually	_	ADV	_	_	_	_	_	_
18	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	each	_	DET	_	_	_	_	_	_
20	other	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	cycle	_	NOUN	_	Number=Sing	_	_	_	_
24	:	_	PUNCT	_	_	_	_	_	_
25	saturating	_	VERB	_	VerbForm=Ger	_	_	_	_
26	amounts	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
30	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
31	kappa	_	VERB	_	Number=Sing	_	_	_	_
32	B	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	alpha	_	PROPN	_	Number=Sing	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
37	destroyed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	upon	_	ADP	_	_	_	_	_	_
39	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	allowing	_	VERB	_	VerbForm=Ger	_	_	_	_
42	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
43	activation	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	NF	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	kappa	_	PROPN	_	Number=Sing	_	_	_	_
48	B.	_	PROPN	_	Number=Sing	_	_	_	_
49	Subsequently	_	ADV	_	_	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
52	kappa	_	VERB	_	Number=Sing	_	_	_	_
53	B	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	alpha	_	PROPN	_	Number=Sing	_	_	_	_
56	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
57	and	_	CCONJ	_	_	_	_	_	_
58	protein	_	NOUN	_	Number=Sing	_	_	_	_
59	levels	_	NOUN	_	Number=Plur	_	_	_	_
60	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
61	quickly	_	ADV	_	_	_	_	_	_
62	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
63	by	_	ADP	_	_	_	_	_	_
64	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
65	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
66	NF	_	PROPN	_	Number=Sing	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	kappa	_	NOUN	_	Number=Sing	_	_	_	_
69	B	_	NOUN	_	Number=Sing	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	resurgence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	kappa	_	VERB	_	Number=Sing	_	_	_	_
6	B	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	PROPN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	acts	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	restore	_	VERB	_	VerbForm=Inf	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	equilibrium	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	PROPN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	again	_	ADV	_	_	_	_	_	_
23	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003773	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Disruption	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	GATA	_	NOUN	_	Number=Sing	_	_	_	_
5	motif	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	Duffy	_	PROPN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	abolishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	Duffy	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	negative	_	ADJ	_	Degree=Pos	_	_	_	_
19	individuals	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	Duffy	_	PROPN	_	Number=Sing	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	group	_	NOUN	_	Number=Sing	_	_	_	_
8	antigen	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	erythrocyte	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	Plasmodium	_	PROPN	_	Number=Sing	_	_	_	_
16	vivax	_	NOUN	_	Number=Sing	_	_	_	_
17	malaria	_	NOUN	_	Number=Sing	_	_	_	_
18	parasite	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	recently	_	ADV	_	_	_	_	_	_
22	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
23	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	encode	_	VERB	_	VerbForm=Inf	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	widely	_	ADV	_	_	_	_	_	_
30	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
32	receptor	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Duffy	_	PROPN	_	Number=Sing	_	_	_	_
8	antigen	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	DARC	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	single	_	ADJ	_	Degree=Pos	_	_	_	_
21	exon	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	that	_	DET	_	_	_	_	_	_
24	most	_	ADJ	_	_	_	_	_	_
25	Duffy	_	ADJ	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	negative	_	ADJ	_	Degree=Pos	_	_	_	_
28	blacks	_	NOUN	_	Number=Plur	_	_	_	_
29	carry	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	silent	_	ADJ	_	Degree=Pos	_	_	_	_
32	FY*B	_	NOUN	_	Number=Sing	_	_	_	_
33	allele	_	NOUN	_	Number=Sing	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	single	_	ADJ	_	Degree=Pos	_	_	_	_
37	T	_	NOUN	_	Number=Sing	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	C	_	PROPN	_	Number=Sing	_	_	_	_
40	substitution	_	NOUN	_	Number=Sing	_	_	_	_
41	at	_	ADP	_	_	_	_	_	_
42	nucleotide	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	46	_	NUM	_	NumType=Card	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	mutation	_	NOUN	_	Number=Sing	_	_	_	_
3	impairs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	by	_	SCONJ	_	_	_	_	_	_
11	disrupting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	GATA1	_	PROPN	_	Number=Sing	_	_	_	_
18	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	With	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	recent	_	ADJ	_	Degree=Pos	_	_	_	_
4	characterization	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	FY*A	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	FY*B	_	NOUN	_	Number=Sing	_	_	_	_
10	alleles	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	findings	_	NOUN	_	Number=Plur	_	_	_	_
14	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
17	basis	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	Duffy	_	PROPN	_	Number=Sing	_	_	_	_
21	blood	_	NOUN	_	Number=Sing	_	_	_	_
22	group	_	NOUN	_	Number=Sing	_	_	_	_
23	system	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	explanation	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	specific	_	ADJ	_	Degree=Pos	_	_	_	_
32	repression	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	DARC	_	PROPN	_	Number=Sing	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	Duffy	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	negative	_	ADJ	_	Degree=Pos	_	_	_	_
41	individuals	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003776	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
3	protooncogene	_	NOUN	_	Number=Sing	_	_	_	_
4	product	_	NOUN	_	Number=Sing	_	_	_	_
5	represses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	p65-mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	long	_	ADJ	_	Degree=Pos	_	_	_	_
16	terminal	_	NOUN	_	Number=Sing	_	_	_	_
17	repeat	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	type	_	NOUN	_	Number=Sing	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
23	virus	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	long	_	ADJ	_	Degree=Pos	_	_	_	_
3	terminal	_	NOUN	_	Number=Sing	_	_	_	_
4	repeat	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	LTR	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	5	_	NUM	_	NumType=Card	_	_	_	_
23	'	_	PUNCT	_	_	_	_	_	_
24	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	region	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	receptor	_	NOUN	_	Number=Sing	_	_	_	_
34	alpha	_	NOUN	_	Number=Sing	_	_	_	_
35	subunit	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2R	_	NUM	_	Number=Sing	_	_	_	_
40	alpha	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	share	_	VERB	_	Number=Sing	_	_	_	_
43	functional	_	ADJ	_	Degree=Pos	_	_	_	_
44	kappa	_	NOUN	_	Number=Sing	_	_	_	_
45	B	_	NOUN	_	Number=Sing	_	_	_	_
46	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
47	elements	_	NOUN	_	Number=Plur	_	_	_	_
48	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	regulation	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
54	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
55	transcription	_	NOUN	_	Number=Sing	_	_	_	_
56	units	_	NOUN	_	Number=Plur	_	_	_	_
57	during	_	ADP	_	_	_	_	_	_
58	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
59	activation	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	kappa	_	NOUN	_	Degree=Pos	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	structurally	_	ADV	_	_	_	_	_	_
11	related	_	ADJ	_	Degree=Pos	_	_	_	_
12	family	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	interactive	_	ADJ	_	Degree=Pos	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	p50	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	p65	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	product	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
28	protooncogene	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	c	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	Rel	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	p65	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	p50	_	NOUN	_	Number=Sing	_	_	_	_
10	form	_	VERB	_	Number=Sing	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	prototypical	_	ADJ	_	Degree=Pos	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	complex	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	rapidly	_	ADV	_	_	_	_	_	_
22	translocated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
29	during	_	ADP	_	_	_	_	_	_
30	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	signaling	_	NOUN	_	Number=Sing	_	_	_	_
4	complex	_	NOUN	_	Number=Sing	_	_	_	_
5	potently	_	ADV	_	_	_	_	_	_
6	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	kappa	_	PROPN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	either	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	HIV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	LTR	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2R	_	NOUN	_	Number=Sing	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	via	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	strong	_	ADJ	_	Degree=Pos	_	_	_	_
29	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
30	domain	_	NOUN	_	Number=Sing	_	_	_	_
31	present	_	ADJ	_	Degree=Pos	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	p65	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	DET	_	_	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	either	_	CCONJ	_	_	_	_	_	_
16	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
17	ester	_	NOUN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	tumor	_	NOUN	_	Number=Sing	_	_	_	_
20	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
25	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
26	relative	_	NOUN	_	_	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	p65	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	markedly	_	ADV	_	_	_	_	_	_
31	represses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	p65	_	NUM	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	activation	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	units	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	c	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Rel	_	NOUN	_	Number=Sing	_	_	_	_
8	correlate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	DNA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	not	_	ADV	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	ability	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	heterodimerize	_	VERB	_	VerbForm=Inf	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	p50	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
28	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
29	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	competition	_	NOUN	_	Number=Sing	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	p50/p65	_	NOUN	_	Number=Sing	_	_	_	_
33	for	_	ADP	_	_	_	_	_	_
34	occupancy	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
40	element	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	findings	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	one	_	NUM	_	NumType=Card	_	_	_	_
8	function	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	c	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Rel	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	physiologic	_	ADJ	_	Degree=Pos	_	_	_	_
17	repressor	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	HIV	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	LTR	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2R	_	PROPN	_	Number=Sing	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	promoters	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	serving	_	VERB	_	VerbForm=Ger	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	efficiently	_	ADV	_	_	_	_	_	_
34	counter	_	VERB	_	VerbForm=Inf	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	strong	_	ADJ	_	Degree=Pos	_	_	_	_
37	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
38	activating	_	NOUN	_	VerbForm=Ger	_	_	_	_
39	effects	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	p65	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003003779	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	Gardnerella	_	PROPN	_	Number=Sing	_	_	_	_
11	vaginalis	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
2	vaginosis	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	BV	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	rate	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	sexual	_	ADJ	_	Degree=Pos	_	_	_	_
14	transmission	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	Gardnerella	_	PROPN	_	Number=Sing	_	_	_	_
27	vaginalis	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	frequently	_	ADV	_	_	_	_	_	_
30	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	genital	_	ADJ	_	Degree=Pos	_	_	_	_
34	tracts	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	women	_	NOUN	_	Number=Plur	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	BV.	_	PROPN	_	Number=Sing	_	_	_	_
39	G.	_	PROPN	_	Number=Sing	_	_	_	_
40	vaginalis	_	PROPN	_	Number=Sing	_	_	_	_
41	lysates	_	NOUN	_	Number=Plur	_	_	_	_
42	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	to	_	PART	_	_	_	_	_	_
45	significantly	_	ADV	_	_	_	_	_	_
46	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
47	HIV	_	NOUN	_	Number=Sing	_	_	_	_
48	expression	_	NOUN	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	monocytoid	_	ADJ	_	Degree=Pos	_	_	_	_
51	cells	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	significantly	_	ADV	_	_	_	_	_	_
4	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
5	when	_	ADV	_	PronType=Int	_	_	_	_
6	lysates	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	heated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	100	_	NUM	_	NumType=Card	_	_	_	_
11	degrees	_	NOUN	_	Number=Plur	_	_	_	_
12	C	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	5	_	NUM	_	NumType=Card	_	_	_	_
15	min	_	NOUN	_	Number=Plur	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	treatment	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	lysozyme	_	NOUN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	protease	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	G.	_	PROPN	_	Number=Sing	_	_	_	_
2	vaginalis	_	PROPN	_	Number=Sing	_	_	_	_
3	lysates	_	NOUN	_	Number=Plur	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	certain	_	ADJ	_	Degree=Pos	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	lines	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	G.	_	PROPN	_	Number=Sing	_	_	_	_
2	vaginalis	_	PROPN	_	Number=Sing	_	_	_	_
3	lysates	_	NOUN	_	Number=Plur	_	_	_	_
4	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	HIV	_	PROPN	_	Number=Sing	_	_	_	_
6	long	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
9	repeat	_	NOUN	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	NF	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	effect	_	NOUN	_	Number=Sing	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	G.	_	PROPN	_	Number=Sing	_	_	_	_
29	vaginalis	_	PROPN	_	Number=Sing	_	_	_	_
30	on	_	ADP	_	_	_	_	_	_
31	HIV	_	NOUN	_	Number=Sing	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	production	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	G.	_	PROPN	_	Number=Sing	_	_	_	_
8	vaginalis	_	PROPN	_	Number=Sing	_	_	_	_
9	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	genital	_	ADJ	_	Degree=Pos	_	_	_	_
12	tract	_	NOUN	_	Number=Sing	_	_	_	_
13	infection	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	G.	_	PROPN	_	Number=Sing	_	_	_	_
16	vaginalis	_	PROPN	_	Number=Sing	_	_	_	_
17	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	risk	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	HIV	_	NOUN	_	Number=Sing	_	_	_	_
22	transmission	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	SCONJ	_	_	_	_	_	_
24	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	genital	_	ADJ	_	Degree=Pos	_	_	_	_
30	tract	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	at	_	ADV	_	_	_	_	_	_
6	least	_	ADV	_	Degree=Sup	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	part	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	rate	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	HIV	_	NOUN	_	Number=Sing	_	_	_	_
15	transmission	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	women	_	NOUN	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	BV.	_	PROPN	_	Number=Sing	_	_	_	_
20	Document	_	NOUN	_	Number=Sing	_	_	_	_
21	0030013	_	NUM	_	NumType=Card	_	_	_	_
22	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	targeting	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	retroviral	_	ADJ	_	Degree=Pos	_	_	_	_
5	vectors	_	NOUN	_	Number=Plur	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	erythroblastic	_	ADJ	_	Degree=Pos	_	_	_	_
9	progeny	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	transduced	_	VERB	_	Degree=Pos	_	_	_	_
12	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
13	stem	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	tissues	_	NOUN	_	Number=Plur	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lineages	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
12	feature	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	therapy	_	NOUN	_	Number=Sing	_	_	_	_
17	vector	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	many	_	ADJ	_	Degree=Pos	_	_	_	_
20	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
21	applications	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	such	_	ADJ	_	Degree=Pos	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	correction	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	hemoglobinopathies	_	NOUN	_	Number=Plur	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	thalassemias	_	NOUN	_	Number=Plur	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	transplantation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	genetically	_	ADV	_	_	_	_	_	_
34	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
36	stem	_	NOUN	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	developed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	retroviral	_	ADJ	_	Degree=Pos	_	_	_	_
4	vectors	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
9	viral	_	ADJ	_	Degree=Pos	_	_	_	_
10	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	U3	_	PROPN	_	Number=Sing	_	_	_	_
14	region	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	3	_	NUM	_	NumType=Card	_	_	_	_
18	'	_	PUNCT	_	_	_	_	_	_
19	LTR	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	replaced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	specific	_	ADJ	_	Degree=Pos	_	_	_	_
31	GATA	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	replaced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	propagated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	'	_	PUNCT	_	_	_	_	_	_
10	LTR	_	NOUN	_	Number=Sing	_	_	_	_
11	upon	_	ADP	_	_	_	_	_	_
12	integration	_	NOUN	_	Number=Sing	_	_	_	_
13	into	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	target	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	genome	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	vectors	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	transduce	_	VERB	_	VerbForm=Inf	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	lines	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	cord	_	ADJ	_	Number=Sing	_	_	_	_
14	blood	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	CD34	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	stem	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	murine	_	NOUN	_	Number=Sing	_	_	_	_
28	bone	_	NOUN	_	Number=Sing	_	_	_	_
29	marrow	_	NOUN	_	Number=Sing	_	_	_	_
30	repopulating	_	VERB	_	VerbForm=Ger	_	_	_	_
31	stem	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	appropriate	_	ADJ	_	Degree=Pos	_	_	_	_
5	reporter	_	NOUN	_	Number=Sing	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	triangle	_	ADJ	_	Degree=Pos	_	_	_	_
9	upLNGFR	_	NOUN	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	EGFP	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	differentiated	_	ADJ	_	Degree=Pos	_	_	_	_
18	progeny	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	stem	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	vitro	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	liquid	_	ADJ	_	Degree=Pos	_	_	_	_
28	culture	_	NOUN	_	Number=Sing	_	_	_	_
29	as	_	ADV	_	_	_	_	_	_
30	well	_	ADV	_	Degree=Pos	_	_	_	_
31	as	_	ADP	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	clonogenic	_	ADJ	_	Number=Sing	_	_	_	_
34	assay	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	vivo	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	after	_	SCONJ	_	_	_	_	_	_
41	bone	_	NOUN	_	Number=Sing	_	_	_	_
42	marrow	_	NOUN	_	Number=Sing	_	_	_	_
43	transplantation	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	lethally	_	ADV	_	_	_	_	_	_
46	irradiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	mice	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GATA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	autoregulatory	_	ADJ	_	Number=Sing	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	effectively	_	ADV	_	_	_	_	_	_
8	restricts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	LTR	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	unit	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	erythroblastic	_	ADJ	_	Degree=Pos	_	_	_	_
22	progeny	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	both	_	CCONJ	_	_	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	mouse	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	repopulating	_	VERB	_	VerbForm=Ger	_	_	_	_
31	stem	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Packaging	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	viral	_	ADJ	_	Degree=Pos	_	_	_	_
4	particles	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	integration	_	NOUN	_	Number=Sing	_	_	_	_
7	into	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	target	_	NOUN	_	Number=Sing	_	_	_	_
10	genome	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	stability	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	integrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	provirus	_	NOUN	_	Number=Sing	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	LTR	_	NOUN	_	Number=Sing	_	_	_	_
24	modification	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Enhancer	_	NOUN	_	Number=Sing	_	_	_	_
2	replacement	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	therefore	_	ADV	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	effective	_	ADJ	_	Degree=Pos	_	_	_	_
7	strategy	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	target	_	VERB	_	VerbForm=Inf	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	retroviral	_	ADJ	_	Degree=Pos	_	_	_	_
14	transgene	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	progeny	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	transduced	_	VERB	_	Degree=Pos	_	_	_	_
21	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
22	stem	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300110	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Four	_	NUM	_	NumType=Card	_	_	_	_
2	P-	_	NOUN	_	Number=Plur	_	_	_	_
3	like	_	ADJ	_	Degree=Pos	_	_	_	_
4	elements	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	mouse	_	NOUN	_	Number=Sing	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	:	_	PUNCT	_	_	_	_	_	_
18	involvement	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
22	set	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	activator	_	NOUN	_	Number=Sing	_	_	_	_
32	protein	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	family	_	NOUN	_	Number=Sing	_	_	_	_
36	proteins	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	P	_	NOUN	_	Number=Sing	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	critical	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	element	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	4	_	NUM	_	NumType=Card	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	mouse	_	NOUN	_	Number=Sing	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	there	_	PRON	_	_	_	_	_	_
10	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	five	_	NUM	_	NumType=Card	_	_	_	_
12	elements	_	NOUN	_	Number=Plur	_	_	_	_
13	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	P	_	NOUN	_	Number=Sing	_	_	_	_
18	sequence	_	NOUN	_	Number=Sing	_	_	_	_
19	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
22	element	_	NOUN	_	Number=Sing	_	_	_	_
23	0	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	CLE0	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	P	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	P2	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	P3	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	P4	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	P-like	_	ADJ	_	Degree=Pos	_	_	_	_
8	elements	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	native	_	ADJ	_	Degree=Pos	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	did	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	transient	_	ADJ	_	Degree=Pos	_	_	_	_
21	transfection	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
24	mobility	_	NOUN	_	Number=Sing	_	_	_	_
25	shift	_	NOUN	_	Number=Sing	_	_	_	_
26	assays	_	NOUN	_	Number=Plur	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	EMSA	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Transfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	EL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	4	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	reporter	_	NOUN	_	Number=Sing	_	_	_	_
15	constructs	_	NOUN	_	Number=Plur	_	_	_	_
16	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
17	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	P	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	like	_	ADJ	_	Degree=Pos	_	_	_	_
21	elements	_	NOUN	_	Number=Plur	_	_	_	_
22	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	four	_	NUM	_	NumType=Card	_	_	_	_
25	P	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	like	_	ADJ	_	Degree=Pos	_	_	_	_
28	elements	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	CLE0	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	P	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	P2	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	P4	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	but	_	CCONJ	_	_	_	_	_	_
39	not	_	ADV	_	_	_	_	_	_
40	P3	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	for	_	ADP	_	_	_	_	_	_
45	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
46	activation	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	IL	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	4	_	NUM	_	NumType=Card	_	_	_	_
52	promoter	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
2	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	both	_	DET	_	_	_	_	_	_
5	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
8	complexes	_	NOUN	_	Number=Plur	_	_	_	_
9	bound	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	CLE0	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	P	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	P2	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	P4	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	whereas	_	SCONJ	_	_	_	_	_	_
20	only	_	ADV	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	bound	_	ADJ	_	Degree=Pos	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	P3	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	competition	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	antibody	_	NOUN	_	Number=Sing	_	_	_	_
5	supershift	_	NOUN	_	Number=Sing	_	_	_	_
6	assays	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	complexes	_	NOUN	_	Number=Plur	_	_	_	_
11	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	P	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	P2	_	NOUN	_	Number=Sing	_	_	_	_
16	proved	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	family	_	NOUN	_	Number=Sing	_	_	_	_
29	proteins	_	NOUN	_	Number=Plur	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	major	_	ADJ	_	Degree=Pos	_	_	_	_
32	components	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Activator	_	NOUN	_	Number=Sing	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	family	_	NOUN	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	interacted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	CLE0	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	P	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	P2	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	P4.	_	PROPN	_	Number=Sing	_	_	_	_
19	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	AP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	complex	_	NOUN	_	Number=Sing	_	_	_	_
25	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	only	_	ADV	_	_	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	P	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	P2.	_	PROPN	_	Number=Sing	_	_	_	_
31	Cross	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	competition	_	NOUN	_	Number=Sing	_	_	_	_
34	assays	_	NOUN	_	Number=Plur	_	_	_	_
35	among	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	P	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	like	_	ADJ	_	Degree=Pos	_	_	_	_
40	elements	_	NOUN	_	Number=Plur	_	_	_	_
41	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	element	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	specific	_	ADJ	_	Degree=Pos	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	common	_	ADJ	_	Degree=Pos	_	_	_	_
47	complexes	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Six	_	NUM	_	NumType=Card	_	_	_	_
2	tandem	_	NOUN	_	Number=Sing	_	_	_	_
3	repeats	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	P	_	NOUN	_	Number=Sing	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	SV40	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	responded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
16	12	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	myristate	_	NOUN	_	Number=Sing	_	_	_	_
19	13	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	acetate	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	while	_	SCONJ	_	_	_	_	_	_
24	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	other	_	ADJ	_	Degree=Pos	_	_	_	_
27	elements	_	NOUN	_	Number=Plur	_	_	_	_
28	did	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	not	_	PART	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	would	_	AUX	_	VerbForm=Fin	_	_	_	_
3	thus	_	ADV	_	_	_	_	_	_
4	appear	_	VERB	_	VerbForm=Inf	_	_	_	_
5	that	_	DET	_	_	_	_	_	_
6	components	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	each	_	DET	_	_	_	_	_	_
9	P	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	like	_	ADJ	_	Degree=Pos	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	complexes	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	identical	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	coordinately	_	ADV	_	_	_	_	_	_
22	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001	_	NUM	_	NumType=Card	_	_	_	_
3	16	_	NUM	_	NumType=Card	_	_	_	_
4	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	perpetuated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	infection	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	[	_	PUNCT	_	_	_	_	_	_
16	see	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
17	comments	_	NOUN	_	Number=Plur	_	_	_	_
18	]	_	PUNCT	_	_	_	_	_	_

1	Permissiveness	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	replication	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	differs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	poorly	_	ADV	_	_	_	_	_	_
9	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	vivo	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	normal	_	ADJ	_	Degree=Pos	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	very	_	ADV	_	_	_	_	_	_
5	little	_	ADV	_	Degree=Pos	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	if	_	SCONJ	_	_	_	_	_	_
8	any	_	DET	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	basal	_	ADJ	_	Degree=Pos	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	HIV	_	PROPN	_	Number=Sing	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	low	_	ADJ	_	Degree=Pos	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	potent	_	ADJ	_	Degree=Pos	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	activator	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	HIV	_	NOUN	_	Number=Sing	_	_	_	_
33	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	fixed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	tissue	_	NOUN	_	Number=Sing	_	_	_	_
6	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
7	express	_	VERB	_	Degree=Pos	_	_	_	_
8	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	permanent	_	ADJ	_	Degree=Pos	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	explanation	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	perpetuation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	infection	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
11	could	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	sustained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	NF	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	U937	_	PROPN	_	Number=Sing	_	_	_	_
5	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	line	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	fully	_	ADV	_	_	_	_	_	_
12	permissive	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	HIV	_	VERB	_	Number=Sing	_	_	_	_
15	replication	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	express	_	VERB	_	VerbForm=Inf	_	_	_	_
21	only	_	ADV	_	_	_	_	_	_
22	low	_	ADJ	_	Degree=Pos	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	infection	_	NOUN	_	Number=Sing	_	_	_	_
8	results	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	both	_	DET	_	_	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	antigenic	_	ADJ	_	Degree=Pos	_	_	_	_
18	properties	_	NOUN	_	Number=Plur	_	_	_	_
19	indistinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	permanently	_	ADV	_	_	_	_	_	_
29	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	HIV	_	NOUN	_	Number=Sing	_	_	_	_
31	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
32	activity	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	independent	_	ADJ	_	Degree=Pos	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	tumour	_	NOUN	_	Degree=Pos	_	_	_	_
9	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	replication	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	thus	_	ADV	_	_	_	_	_	_
21	likely	_	ADJ	_	Degree=Pos	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
24	at	_	ADV	_	_	_	_	_	_
25	least	_	ADV	_	Degree=Sup	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	part	_	NOUN	_	Degree=Pos	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	perpetuation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	HIV	_	NOUN	_	Number=Sing	_	_	_	_
32	infection	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300121	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	roles	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	Oct	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2A	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	high	_	ADJ	_	Degree=Pos	_	_	_	_
13	mobility	_	NOUN	_	Number=Sing	_	_	_	_
14	group	_	NOUN	_	Number=Sing	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	I/Y	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	HLA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	DRA	_	PROPN	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	class	_	NOUN	_	Number=Sing	_	_	_	_
3	II	_	NUM	_	NumType=Card	_	_	_	_
4	major	_	ADJ	_	Degree=Pos	_	_	_	_
5	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
6	complex	_	NOUN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	HLA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	DRA	_	PROPN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	B	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	antigen	_	ADJ	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	presenting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	HLA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	DRA	_	PROPN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	variety	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	types	_	NOUN	_	Number=Plur	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	interferon	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	gamma	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	IFN	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	gamma	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	Oct	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2A	_	PROPN	_	Number=Sing	_	_	_	_
14	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	critical	_	ADJ	_	Degree=Pos	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	HLA	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	DRA	_	PROPN	_	Number=Sing	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	class	_	NOUN	_	Number=Sing	_	_	_	_
26	II	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	positive	_	ADJ	_	Degree=Pos	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	lines	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	that	_	SCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	high	_	ADJ	_	Degree=Pos	_	_	_	_
37	mobility	_	NOUN	_	Number=Sing	_	_	_	_
38	group	_	NOUN	_	Number=Sing	_	_	_	_
39	protein	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	HMG	_	X	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	I/Y	_	NOUN	_	Number=Sing	_	_	_	_
44	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
47	sites	_	NOUN	_	Number=Plur	_	_	_	_
48	within	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	DRA	_	PROPN	_	Number=Sing	_	_	_	_
51	promoter	_	NOUN	_	Number=Sing	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	including	_	VERB	_	VerbForm=Ger	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	Oct	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	2A	_	PROPN	_	Number=Sing	_	_	_	_
58	binding	_	NOUN	_	Number=Sing	_	_	_	_
59	site	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Coexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HMG	_	PROPN	_	Number=Sing	_	_	_	_
4	I/Y	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	Oct	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	lines	_	NOUN	_	Number=Plur	_	_	_	_
12	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_

1	Oct	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	high	_	ADJ	_	Degree=Pos	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HLA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	DRA	_	PROPN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	vitro	_	ADJ	_	Number=Sing	_	_	_	_
18	DNA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	studies	_	NOUN	_	Number=Plur	_	_	_	_
22	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	HMG	_	PROPN	_	Number=Sing	_	_	_	_
25	I/Y	_	PROPN	_	Number=Sing	_	_	_	_
26	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	Oct	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2A	_	NUM	_	Number=Sing	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	HLA	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	DRA	_	PROPN	_	Number=Sing	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Oct	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2A	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	HMG	_	PROPN	_	Number=Sing	_	_	_	_
8	I/Y	_	NOUN	_	Number=Sing	_	_	_	_
9	may	_	AUX	_	VerbForm=Fin	_	_	_	_
10	synergize	_	VERB	_	VerbForm=Inf	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	HLA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	DRA	_	PROPN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	B	_	ADJ	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	Oct	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2A	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	involved	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	IFN	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	gamma	_	NOUN	_	Number=Sing	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	HLA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	DRA	_	PROPN	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	antisense	_	ADJ	_	Degree=Pos	_	_	_	_
28	HMG	_	PROPN	_	Number=Sing	_	_	_	_
29	I/Y	_	NOUN	_	Number=Sing	_	_	_	_
30	dramatically	_	ADV	_	_	_	_	_	_
31	decreases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	level	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	induction	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
5	sets	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	involved	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	two	_	NUM	_	NumType=Card	_	_	_	_
14	modes	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	HLA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	DRA	_	PROPN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	HMG	_	ADJ	_	Number=Sing	_	_	_	_
24	I/Y	_	NOUN	_	Number=Sing	_	_	_	_
25	may	_	AUX	_	VerbForm=Fin	_	_	_	_
26	be	_	AUX	_	VerbForm=Inf	_	_	_	_
27	important	_	ADJ	_	Degree=Pos	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	B	_	ADJ	_	Degree=Pos	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	specific	_	ADJ	_	Degree=Pos	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	essential	_	ADJ	_	Degree=Pos	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	IFN	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	gamma	_	NOUN	_	Number=Sing	_	_	_	_
42	induction	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300130	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	characterization	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	murine	_	NOUN	_	Number=Sing	_	_	_	_
6	homolog	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
14	BOB.	_	NOUN	_	Number=Sing	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	OBF.1	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	B	_	X	_	_	_	_	_	_
2	cell-specific	_	ADJ	_	Degree=Pos	_	_	_	_
3	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	octamer	_	ADJ	_	Number=Sing	_	_	_	_
10	motif	_	NOUN	_	Number=Sing	_	_	_	_
11	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	Oct1	_	PROPN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	Oct2	_	PROPN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	additional	_	ADJ	_	Degree=Pos	_	_	_	_
19	B	_	NOUN	_	Degree=Pos	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	cofactors	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	such	_	ADJ	_	Degree=Pos	_	_	_	_
3	cofactor	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	BOB.1	_	PROPN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	OBF.1	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	recently	_	ADV	_	_	_	_	_	_
11	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	isolation	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	detailed	_	ADJ	_	Degree=Pos	_	_	_	_
9	characterization	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	murine	_	NOUN	_	Number=Sing	_	_	_	_
13	homolog	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Full	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	length	_	NOUN	_	Number=Sing	_	_	_	_
4	cDNAs	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
7	clones	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	structure	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	determined	_	ADJ	_	Degree=Pos	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Comparison	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	deduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	amino	_	PROPN	_	Number=Sing	_	_	_	_
6	acids	_	NOUN	_	Number=Plur	_	_	_	_
7	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	88	_	NUM	_	NumType=Card	_	_	_	_
9	%	_	SYM	_	Number=Sing	_	_	_	_
10	sequence	_	NOUN	_	Number=Sing	_	_	_	_
11	identity	_	NOUN	_	Number=Sing	_	_	_	_
12	between	_	ADP	_	_	_	_	_	_
13	mouse	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	BOB.	_	NOUN	_	Number=Sing	_	_	_	_
17	1/OBF.1	_	NUM	_	NumType=Card	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NH2	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	terminal	_	NOUN	_	Number=Sing	_	_	_	_
5	126	_	NUM	_	NumType=Card	_	_	_	_
6	amino	_	PROPN	_	Number=Sing	_	_	_	_
7	acids	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	BOB.	_	PROPN	_	Number=Sing	_	_	_	_
10	1/OBF.1	_	NUM	_	NumType=Card	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	both	_	ADV	_	_	_	_	_	_
13	essential	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	interaction	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	POU	_	NOUN	_	Number=Sing	_	_	_	_
21	domains	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	either	_	CCONJ	_	_	_	_	_	_
24	Oct1	_	PROPN	_	Number=Sing	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	Oct2	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	interaction	_	NOUN	_	Number=Sing	_	_	_	_
6	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	require	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	simultaneous	_	ADJ	_	Degree=Pos	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Oct	_	PROPN	_	Number=Sing	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	DNA	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	high	_	ADJ	_	Degree=Pos	_	_	_	_
20	resolution	_	NOUN	_	Number=Sing	_	_	_	_
21	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	Oct	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	DNA	_	PROPN	_	Number=Sing	_	_	_	_
27	interaction	_	NOUN	_	Number=Sing	_	_	_	_
28	reveals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	BOB.1	_	NOUN	_	Number=Sing	_	_	_	_
33	/	_	PUNCT	_	_	_	_	_	_
34	OBF.1	_	NOUN	_	Number=Sing	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	Oct1	_	PROPN	_	Number=Sing	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	Oct2	_	PROPN	_	Number=Sing	_	_	_	_
39	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	not	_	PART	_	_	_	_	_	_
41	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	interaction	_	NOUN	_	Number=Sing	_	_	_	_
44	with	_	ADP	_	_	_	_	_	_
45	DNA	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	BOB.1/OBF.1	_	NOUN	_	Number=Sing	_	_	_	_
2	can	_	AUX	_	VerbForm=Fin	_	_	_	_
3	efficiently	_	ADV	_	_	_	_	_	_
4	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	octamer	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	promoters	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
11	;	_	PUNCT	_	_	_	_	_	_
12	however	_	ADV	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
15	fails	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
18	octamer	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Fusion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	subdomains	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	BOB.1/OBF.1	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	GAL4	_	PROPN	_	Number=Sing	_	_	_	_
9	DNA	_	PROPN	_	Number=Sing	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	domain	_	NOUN	_	Number=Sing	_	_	_	_
12	reveals	_	VERB	_	Number=Plur	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	NH2	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	COOH	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	terminal	_	NOUN	_	Number=Sing	_	_	_	_
21	domains	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	BOB.1	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	OBF.1	_	NOUN	_	Number=Sing	_	_	_	_
26	contribute	_	VERB	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	full	_	ADJ	_	Degree=Pos	_	_	_	_
29	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
30	function	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	COOH	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	terminal	_	NOUN	_	Number=Sing	_	_	_	_
36	domain	_	NOUN	_	Number=Sing	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	more	_	ADV	_	_	_	_	_	_
39	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
42	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
43	assay	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	failure	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	full	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	length	_	NOUN	_	Number=Sing	_	_	_	_
9	BOB.1/OBF.1	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	octamer	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	elements	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	non	_	X	_	_	_	_	_	_
19	B	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	GAL4	_	PROPN	_	Number=Sing	_	_	_	_
24	fusions	_	NOUN	_	Number=Plur	_	_	_	_
25	likewise	_	ADV	_	_	_	_	_	_
26	only	_	ADV	_	_	_	_	_	_
27	stimulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
33	position	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300132	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	E2F	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
10	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
11	virus	_	NOUN	_	Number=Sing	_	_	_	_
12	type	_	NOUN	_	Number=Sing	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	Tax	_	VERB	_	Number=Sing	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	p16(INK4A	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	negative	_	ADJ	_	Degree=Pos	_	_	_	_
22	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
4	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	causative	_	ADJ	_	Degree=Pos	_	_	_	_
16	agent	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	adult	_	NOUN	_	Number=Sing	_	_	_	_
19	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
20	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	exact	_	ADJ	_	Degree=Pos	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	leukemogenesis	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	still	_	ADV	_	_	_	_	_	_
15	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	Tax	_	NOUN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	play	_	VERB	_	VerbForm=Inf	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	major	_	ADJ	_	Degree=Pos	_	_	_	_
26	role	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
29	process	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	40	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kDa	_	NOUN	_	Number=Sing	_	_	_	_
5	polypeptide	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	able	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	tumor	_	NOUN	_	Number=Sing	_	_	_	_
13	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
14	p16	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	INK4A	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Consequently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Tax	_	NOUN	_	Number=Sing	_	_	_	_
4	can	_	AUX	_	VerbForm=Fin	_	_	_	_
5	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	signaling	_	NOUN	_	Number=Sing	_	_	_	_
8	pathway	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	release	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	E2F	_	NOUN	_	Number=Sing	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	turn	_	NOUN	_	Number=Sing	_	_	_	_
19	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	cycle	_	NOUN	_	Number=Sing	_	_	_	_
27	progression	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	paper	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	Tax	_	NOUN	_	Number=Sing	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	also	_	ADV	_	_	_	_	_	_
11	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	E2F	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	independently	_	ADV	_	_	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	p16	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	INK4A	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Indeed	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	when	_	ADV	_	PronType=Int	_	_	_	_
4	Tax	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	coexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	E2F	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	CEM	_	PROPN	_	Number=Sing	_	_	_	_
16	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	lack	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	p16(INK4A	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
26	strongly	_	ADV	_	_	_	_	_	_
27	potentiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	E2F	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	reporter	_	NOUN	_	Number=Sing	_	_	_	_
36	construct	_	NOUN	_	Number=Sing	_	_	_	_
37	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	promoter	_	NOUN	_	Number=Sing	_	_	_	_
41	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
42	E2F	_	NOUN	_	Number=Sing	_	_	_	_
43	binding	_	NOUN	_	Number=Sing	_	_	_	_
44	sites	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	abrogated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	mutations	_	NOUN	_	Number=Plur	_	_	_	_
7	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	E2F	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	Tax	_	NOUN	_	Number=Sing	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	E2F	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	itself	_	PRON	_	Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	Tax	_	NOUN	_	Number=Sing	_	_	_	_
3	mutants	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	fail	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	either	_	CCONJ	_	_	_	_	_	_
9	ATF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	promoters	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	different	_	ADJ	_	Degree=Pos	_	_	_	_
20	5'	_	NUM	_	NumType=Card	_	_	_	_
21	truncation	_	NOUN	_	Number=Sing	_	_	_	_
22	mutants	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	E2F	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
31	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	that	_	SCONJ	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	Tax	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
37	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
38	control	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	E2F1	_	NOUN	_	Number=Sing	_	_	_	_
42	gene	_	NOUN	_	Number=Sing	_	_	_	_
43	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	at	_	ADV	_	_	_	_	_	_
46	least	_	ADV	_	Degree=Sup	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	part	_	NOUN	_	Number=Sing	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	ATF	_	PROPN	_	Number=Sing	_	_	_	_
52	binding	_	NOUN	_	Number=Sing	_	_	_	_
53	site	_	NOUN	_	Number=Sing	_	_	_	_
54	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	E2F	_	PROPN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	1	_	NUM	_	NumType=Card	_	_	_	_
60	promoter	_	NOUN	_	Number=Sing	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300138	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	Fas	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	p50-p65	_	NOUN	_	Number=Sing	_	_	_	_
16	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Fas	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	CD95	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	Fas	_	NOUN	_	Number=Sing	_	_	_	_
7	ligand	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	CD95L	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	interacting	_	ADJ	_	VerbForm=Ger	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	ligand	_	NOUN	_	Number=Sing	_	_	_	_
17	pair	_	NOUN	_	Number=Sing	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	immune	_	ADJ	_	Degree=Pos	_	_	_	_
21	homeostasis	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	results	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Fas	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	acquisition	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	FasL	_	ADJ	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	Fas	_	PROPN	_	Number=Sing	_	_	_	_
3	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	central	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	preservation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	immunologic	_	ADJ	_	Degree=Pos	_	_	_	_
11	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	little	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	about	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
19	machinery	_	NOUN	_	Number=Sing	_	_	_	_
20	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	process	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	events	_	NOUN	_	Number=Plur	_	_	_	_
5	involved	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	Fas	_	NOUN	_	Number=Sing	_	_	_	_
11	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
17	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	fas	_	NOUN	_	Number=Sing	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
29	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
30	line	_	NOUN	_	Number=Sing	_	_	_	_
31	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
34	myristate	_	NOUN	_	Number=Sing	_	_	_	_
35	acetate	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	P	_	NOUN	_	Number=Sing	_	_	_	_
40	/	_	PUNCT	_	_	_	_	_	_
41	I	_	NUM	_	NumType=Card	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	pharmacological	_	ADJ	_	Degree=Pos	_	_	_	_
45	mimics	_	NOUN	_	Number=Plur	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
48	receptor	_	NOUN	_	Number=Sing	_	_	_	_
49	activation	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
3	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	express	_	VERB	_	Degree=Pos	_	_	_	_
6	Fas	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	Fas	_	PROPN	_	Number=Sing	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	approximately	_	ADV	_	_	_	_	_	_
13	10	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	fold	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	h	_	NOUN	_	Number=Plur	_	_	_	_
19	upon	_	ADP	_	_	_	_	_	_
20	P	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	sequential	_	ADJ	_	Degree=Pos	_	_	_	_
3	deletion	_	NOUN	_	Number=Sing	_	_	_	_
4	mutants	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	fas	_	NOUN	_	Number=Sing	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	transient	_	ADJ	_	Degree=Pos	_	_	_	_
12	transfection	_	NOUN	_	Number=Sing	_	_	_	_
13	assays	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	47	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	bp	_	NOUN	_	Number=Sing	_	_	_	_
21	sequence	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	positions	_	NOUN	_	Number=Plur	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	306	_	NUM	_	NumType=Card	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	-	_	SYM	_	_	_	_	_	_
28	260	_	NUM	_	NumType=Card	_	_	_	_
29	relative	_	ADV	_	_	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	ATG	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	activation	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	fas	_	ADJ	_	Degree=Pos	_	_	_	_
40	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Sequence	_	NOUN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	presence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	previously	_	ADV	_	_	_	_	_	_
9	unrecognized	_	ADJ	_	Degree=Pos	_	_	_	_
10	composite	_	ADJ	_	Degree=Pos	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	at	_	ADP	_	_	_	_	_	_
24	positions	_	NOUN	_	Number=Plur	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	295	_	NUM	_	NumType=Card	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	-	_	SYM	_	_	_	_	_	_
29	286	_	NUM	_	NumType=Card	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	supershift	_	ADJ	_	Number=Sing	_	_	_	_
10	analyses	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	documented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	unactivated	_	ADJ	_	Degree=Pos	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	extracts	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	p50-p65	_	NUM	_	NumType=Card	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
32	after	_	ADP	_	_	_	_	_	_
33	P	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
36	activation	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	mutually	_	ADV	_	_	_	_	_	_
14	exclusive	_	ADJ	_	Degree=Pos	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
17	displacement	_	NOUN	_	Number=Sing	_	_	_	_
18	studies	_	NOUN	_	Number=Plur	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	recombinant	_	NOUN	_	Number=Sing	_	_	_	_
22	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	recombinant	_	ADJ	_	Number=Sing	_	_	_	_
25	p50	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	functional	_	ADJ	_	Degree=Pos	_	_	_	_
3	contribution	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
9	composite	_	NOUN	_	Degree=Pos	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	P/I-inducible	_	ADJ	_	Number=Sing	_	_	_	_
13	fas	_	NOUN	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	verified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	SCONJ	_	_	_	_	_	_
19	using	_	VERB	_	VerbForm=Ger	_	_	_	_
20	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
23	concatamers	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	295	_	NUM	_	NumType=Card	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	-	_	SYM	_	_	_	_	_	_
29	286	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
34	kinase	_	NOUN	_	Number=Sing	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	reporter	_	NOUN	_	Number=Sing	_	_	_	_
39	construct	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	native	_	ADJ	_	Degree=Pos	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	constructs	_	NOUN	_	Number=Plur	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	overexpressing	_	VERB	_	VerbForm=Ger	_	_	_	_
48	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	alpha	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Site	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	critical	_	ADJ	_	Degree=Pos	_	_	_	_
8	guanine	_	NOUN	_	Number=Sing	_	_	_	_
9	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
15	element	_	NOUN	_	Number=Sing	_	_	_	_
16	documented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	essential	_	ADJ	_	Degree=Pos	_	_	_	_
19	role	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	fas	_	NOUN	_	Number=Sing	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	induction	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300143	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	type	_	NOUN	_	Number=Sing	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	protease	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	rel	_	NOUN	_	Number=Sing	_	_	_	_
9	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
10	family	_	NOUN	_	Number=Sing	_	_	_	_
11	capable	_	ADJ	_	Degree=Pos	_	_	_	_
12	of	_	SCONJ	_	_	_	_	_	_
13	enhancing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	several	_	ADJ	_	Degree=Pos	_	_	_	_
17	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	including	_	VERB	_	VerbForm=Ger	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	viral	_	ADJ	_	Degree=Pos	_	_	_	_
33	genes	_	NOUN	_	Number=Plur	_	_	_	_
34	transcribed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	from	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	HIV	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	LTR	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	protease	_	NOUN	_	Number=Sing	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	cleave	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	precursor	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	active	_	ADJ	_	Degree=Pos	_	_	_	_
21	form	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	vitro	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	protease	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	precursor	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	by	_	SCONJ	_	_	_	_	_	_
23	introducing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	protease	_	NOUN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	vector	_	NOUN	_	Number=Sing	_	_	_	_
28	into	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	NF	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	viral	_	ADJ	_	Degree=Pos	_	_	_	_
22	protease	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Viral	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	as	_	SCONJ	_	_	_	_	_	_
5	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	using	_	VERB	_	VerbForm=Ger	_	_	_	_
7	LTR	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	CAT	_	NOUN	_	Number=Sing	_	_	_	_
10	assays	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	only	_	ADV	_	_	_	_	_	_
14	slightly	_	ADV	_	_	_	_	_	_
15	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	protease	_	NOUN	_	Number=Sing	_	_	_	_
21	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	while	_	SCONJ	_	_	_	_	_	_
25	secretion	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	IL	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	receptor	_	NOUN	_	Number=Sing	_	_	_	_
38	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
39	not	_	PART	_	_	_	_	_	_
40	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	limited	_	ADJ	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	HIV	_	PROPN	_	Number=Sing	_	_	_	_
11	protease	_	NOUN	_	Number=Sing	_	_	_	_
12	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	unlikely	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	have	_	VERB	_	VerbForm=Inf	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	significant	_	ADJ	_	Degree=Pos	_	_	_	_
18	effect	_	NOUN	_	Number=Sing	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	virus	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	function	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300144	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nitric	_	PROPN	_	Number=Sing	_	_	_	_
2	oxide	_	NOUN	_	Number=Sing	_	_	_	_
3	decreases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Nitric	_	PROPN	_	Number=Sing	_	_	_	_
2	oxide	_	NOUN	_	Number=Sing	_	_	_	_
3	selectively	_	ADV	_	_	_	_	_	_
4	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
9	molecules	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	test	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	nitric	_	PROPN	_	Number=Sing	_	_	_	_
7	oxide	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	NO	_	INTJ	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	limits	_	NOUN	_	Number=Plur	_	_	_	_
12	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	treated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	saphenous	_	ADJ	_	Number=Sing	_	_	_	_
22	vein	_	NOUN	_	Number=Sing	_	_	_	_
23	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	several	_	ADJ	_	Degree=Pos	_	_	_	_
27	NO	_	DET	_	_	_	_	_	_
28	donors	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	assessed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
32	effects	_	NOUN	_	Number=Plur	_	_	_	_
33	on	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
41	molecule	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	1	_	NUM	_	NumType=Card	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	concentration	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
6	manner	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	NO	_	DET	_	_	_	_	_	_
9	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	35	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	55	_	NUM	_	NumType=Card	_	_	_	_
27	%	_	SYM	_	Number=Sing	_	_	_	_
28	as	_	SCONJ	_	_	_	_	_	_
29	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	surface	_	NOUN	_	Number=Sing	_	_	_	_
33	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
34	immunoassays	_	NOUN	_	Number=Plur	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	flow	_	VERB	_	Number=Sing	_	_	_	_
37	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	paralleled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
8	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
11	monolayers	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	nonstatic	_	ADJ	_	Degree=Pos	_	_	_	_
14	assays	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	unaffected	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	cGMP	_	NOUN	_	Number=Sing	_	_	_	_
20	analogues	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	quantitatively	_	ADV	_	_	_	_	_	_
25	similar	_	ADJ	_	Degree=Pos	_	_	_	_
26	after	_	ADP	_	_	_	_	_	_
27	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	either	_	CCONJ	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	alpha	_	PROPN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	beta	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	4	_	NUM	_	NumType=Card	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	tumor	_	NOUN	_	Number=Sing	_	_	_	_
45	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
46	factor	_	NOUN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	TNF	_	PROPN	_	Number=Sing	_	_	_	_
49	alpha	_	NOUN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	or	_	CCONJ	_	_	_	_	_	_
53	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
54	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	NO	_	ADV	_	_	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	other	_	ADJ	_	Degree=Pos	_	_	_	_
9	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
11	molecules	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	E	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	selectin	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	lesser	_	ADJ	_	Degree=Cmp	_	_	_	_
20	extent	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
23	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
24	molecule	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	secretable	_	ADJ	_	Degree=Pos	_	_	_	_
30	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	6	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	8	_	NUM	_	NumType=Card	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
4	NO	_	DET	_	_	_	_	_	_
5	production	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	L	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	N-monomethyl	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	arginine	_	NOUN	_	Number=Sing	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	augment	_	VERB	_	VerbForm=Inf	_	_	_	_
25	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	run	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	transfection	_	NOUN	_	Number=Sing	_	_	_	_
8	studies	_	NOUN	_	Number=Plur	_	_	_	_
9	using	_	VERB	_	VerbForm=Ger	_	_	_	_
10	various	_	ADJ	_	Degree=Pos	_	_	_	_
11	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	reporter	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	constructs	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
21	mobility	_	NOUN	_	Number=Sing	_	_	_	_
22	shift	_	NOUN	_	Number=Sing	_	_	_	_
23	assays	_	NOUN	_	Number=Plur	_	_	_	_
24	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	NO	_	DET	_	_	_	_	_	_
27	represses	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	part	_	ADJ	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	by	_	SCONJ	_	_	_	_	_	_
38	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappa	_	PROPN	_	Number=Sing	_	_	_	_
42	B	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	NO	_	PROPN	_	_	_	_	_	_
5	's	_	PART	_	_	_	_	_	_
6	ability	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	limit	_	VERB	_	VerbForm=Inf	_	_	_	_
9	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
13	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
14	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	some	_	DET	_	_	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	antiatherogenic	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	antiinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	properties	_	NOUN	_	Number=Plur	_	_	_	_
25	within	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	vessel	_	NOUN	_	Number=Sing	_	_	_	_
28	wall	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300148	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	platelets	_	NOUN	_	Number=Plur	_	_	_	_
3	induce	_	VERB	_	_	_	_	_	_
4	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
5	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	secretion	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	surface	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
16	molecule	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	[	_	PUNCT	_	_	_	_	_	_
23	see	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
24	comments	_	NOUN	_	Number=Plur	_	_	_	_
25	]	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Platelet	_	NOUN	_	Number=Sing	_	_	_	_
4	/	_	PUNCT	_	_	_	_	_	_
5	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
6	interaction	_	NOUN	_	Number=Sing	_	_	_	_
7	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	pathophysiology	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	platelets	_	NOUN	_	Number=Plur	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
7	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	MCP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	secretion	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	surface	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
23	molecule	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	on	_	ADP	_	_	_	_	_	_
32	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
36	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	AND	_	CCONJ	_	_	_	_	_	_
3	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_

1	Monolayers	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
5	vein	_	NOUN	_	Number=Sing	_	_	_	_
6	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	incubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	nonstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	ADP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	platelets	_	NOUN	_	Number=Plur	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	6	_	NUM	_	NumType=Card	_	_	_	_
19	hours	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	secretion	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	MCP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	surface	_	NOUN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	ELISA	_	PROPN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	flow	_	VERB	_	Number=Sing	_	_	_	_
40	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	respectively	_	ADV	_	_	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	presence	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	ADP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	platelets	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	MCP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	secretion	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	surface	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	significantly	_	ADV	_	_	_	_	_	_
23	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	nonstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
27	platelets	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	P<0.02	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
18	mobility	_	NOUN	_	Number=Sing	_	_	_	_
19	shift	_	NOUN	_	Number=Sing	_	_	_	_
20	assay	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
25	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	presence	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	platelets	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	ADP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	platelets	_	NOUN	_	Number=Plur	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	MCP	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Liposomal	_	ADJ	_	Degree=Pos	_	_	_	_
2	transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	double	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	phosphorothioate	_	NOUN	_	Number=Sing	_	_	_	_
10	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	mutated	_	VERB	_	Degree=Pos	_	_	_	_
17	form	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	MCP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	secretion	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	surface	_	NOUN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	on	_	ADP	_	_	_	_	_	_
32	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	P<0.05	_	NUM	_	NumType=Card	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	platelets	_	NOUN	_	Number=Plur	_	_	_	_
8	modulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	chemotactic	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	MCP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	adhesive	_	ADJ	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	properties	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	via	_	ADP	_	_	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
33	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Platelet	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	system	_	NOUN	_	Number=Sing	_	_	_	_
11	might	_	AUX	_	VerbForm=Fin	_	_	_	_
12	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	early	_	ADJ	_	Degree=Pos	_	_	_	_
15	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	events	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	atherogenesis	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300151	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	proteasome	_	NOUN	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	degradation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	elderly	_	NOUN	_	Degree=Pos	_	_	_	_
12	:	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	immune	_	ADJ	_	Degree=Pos	_	_	_	_
5	senescence	_	NOUN	_	Number=Sing	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	highly	_	ADV	_	_	_	_	_	_
7	regulated	_	ADJ	_	Degree=Pos	_	_	_	_
8	process	_	NOUN	_	Number=Sing	_	_	_	_
9	requiring	_	VERB	_	VerbForm=Ger	_	_	_	_
10	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	ubiquitination	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
18	degradation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
22	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
23	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Analyses	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	young	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
19	donors	_	NOUN	_	Number=Plur	_	_	_	_
20	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	severely	_	ADV	_	_	_	_	_	_
22	compromised	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	degradation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	T	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	elderly	_	NOUN	_	Degree=Pos	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Examination	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	ubiquitination	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
11	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	demonstrate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	any	_	DET	_	_	_	_	_	_
15	significant	_	ADJ	_	Degree=Pos	_	_	_	_
16	age	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	related	_	ADJ	_	Degree=Pos	_	_	_	_
19	alterations	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	examination	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	using	_	VERB	_	VerbForm=Ger	_	_	_	_
12	fluorogenic	_	ADJ	_	Degree=Pos	_	_	_	_
13	peptide	_	NOUN	_	Number=Sing	_	_	_	_
14	assays	_	NOUN	_	Number=Plur	_	_	_	_
15	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	significant	_	ADJ	_	Degree=Pos	_	_	_	_
18	age	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	related	_	ADJ	_	Degree=Pos	_	_	_	_
21	decline	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	chymotryptic	_	ADJ	_	Degree=Pos	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	decline	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	results	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	failure	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	fully	_	ADV	_	_	_	_	_	_
16	degrade	_	VERB	_	VerbForm=Inf	_	_	_	_
17	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	failure	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	degrade	_	VERB	_	VerbForm=Inf	_	_	_	_
5	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	underlie	_	VERB	_	VerbForm=Inf	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	decrease	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	TNF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	during	_	ADP	_	_	_	_	_	_
29	aging	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	proteasome	_	NOUN	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
7	degradation	_	NOUN	_	Number=Sing	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	central	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	immune	_	ADJ	_	VerbForm=Inf	_	_	_	_
13	dysfunction	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	accompanies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	aging	_	NOUN	_	VerbForm=Ger	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1999	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300152	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
7	acid	_	NOUN	_	Number=Sing	_	_	_	_
8	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
15	acid	_	NOUN	_	Number=Sing	_	_	_	_
16	receptors	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	OBJECTIVES	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
7	acids	_	NOUN	_	Number=Plur	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	RA	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	correlate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	effect	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	levels	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	RA	_	PROPN	_	Number=Sing	_	_	_	_
25	receptors	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	RARs	_	NOUN	_	Number=Plur	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	T-lymphoid	_	PROPN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	monocytoid	_	ADJ	_	Degree=Pos	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	lines	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	DESIGN	_	NOUN	_	Number=Sing	_	_	_	_
2	AND	_	CCONJ	_	_	_	_	_	_
3	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	all	_	DET	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	trans	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	9-cis	_	NOUN	_	Number=Sing	_	_	_	_
9	RA	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	T-lymphoid	_	PROPN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	H9	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	CEM	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	monocytoid	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	U937	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	THP	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	lines	_	NOUN	_	Number=Plur	_	_	_	_
33	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
34	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	during	_	ADP	_	_	_	_	_	_
36	acute	_	ADJ	_	Degree=Pos	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
39	infection	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	RAR	_	NOUN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	hRAR	_	NOUN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	all	_	DET	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	trans	_	NOUN	_	Number=Sing	_	_	_	_
17	RA	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	X	_	PROPN	_	Number=Sing	_	_	_	_
25	receptor	_	NOUN	_	Number=Sing	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	hRXR	_	NOUN	_	Number=Sing	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	receptor	_	NOUN	_	Number=Sing	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	9	_	NUM	_	NumType=Card	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	cis	_	NOUN	_	Number=Sing	_	_	_	_
35	RA	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
41	blot	_	PROPN	_	Number=Sing	_	_	_	_
42	analysis	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	all	_	DET	_	_	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	trans	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	9-cis	_	PROPN	_	Number=Sing	_	_	_	_
7	RA	_	PROPN	_	Number=Sing	_	_	_	_
8	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	virus	_	NOUN	_	Number=Sing	_	_	_	_
10	replication	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	HIV	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	IIIB	_	NUM	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	monocytoid	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	presence	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	absence	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	co-stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
29	agent	_	NOUN	_	Number=Sing	_	_	_	_
30	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
31	myristate	_	NOUN	_	Number=Sing	_	_	_	_
32	acetate	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	PMA	_	PROPN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	retinoids	_	NOUN	_	Number=Plur	_	_	_	_
3	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	weak	_	ADJ	_	Degree=Pos	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	no	_	DET	_	_	_	_	_	_
7	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	effects	_	NOUN	_	Number=Plur	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
14	lines	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	production	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	PMA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	retinoids	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	9-cis	_	PROPN	_	Number=Sing	_	_	_	_
3	RA	_	PROPN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	generally	_	ADV	_	_	_	_	_	_
6	more	_	ADV	_	_	_	_	_	_
7	effective	_	ADJ	_	Degree=Pos	_	_	_	_
8	than	_	ADP	_	_	_	_	_	_
9	all	_	DET	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	trans	_	VERB	_	Number=Sing	_	_	_	_
12	RA	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	SCONJ	_	_	_	_	_	_
14	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	combination	_	NOUN	_	Number=Sing	_	_	_	_
20	generally	_	ADV	_	_	_	_	_	_
21	more	_	ADV	_	_	_	_	_	_
22	effective	_	ADJ	_	Degree=Pos	_	_	_	_
23	than	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	single	_	ADJ	_	Degree=Pos	_	_	_	_
26	agents	_	NOUN	_	Number=Plur	_	_	_	_
27	alone	_	ADJ	_	Degree=Pos	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	RAR	_	NOUN	_	Number=Sing	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	H9	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	U937	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	THP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	almost	_	ADV	_	_	_	_	_	_
18	undetectable	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	CEM	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	RXR	_	NOUN	_	Number=Sing	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	significantly	_	ADV	_	_	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	U937	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	THP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	weakly	_	ADV	_	_	_	_	_	_
16	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	H9	_	NUM	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	not	_	ADV	_	_	_	_	_	_
22	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	CEM	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	PMA	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	RXR	_	PROPN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	H9	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	U937	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	CEM	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	RAR	_	NOUN	_	Number=Sing	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	unchanged	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	H9	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	CEM	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	U937	_	NUM	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	after	_	ADP	_	_	_	_	_	_
20	PMA	_	PROPN	_	Number=Sing	_	_	_	_
21	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSION	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	RA	_	PROPN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	partially	_	ADV	_	_	_	_	_	_
18	correlated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	RARs	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
2	or	_	CCONJ	_	_	_	_	_	_
3	exogenously	_	ADV	_	_	_	_	_	_
4	administered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	RA	_	PROPN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	have	_	VERB	_	VerbForm=Inf	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	significant	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	regulation	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300154	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	state	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	maturation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	into	_	ADP	_	_	_	_	_	_
8	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
9	determines	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	effects	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	13	_	NUM	_	NumType=Card	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	HIV	_	NOUN	_	Number=Sing	_	_	_	_
22	replication	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	13	_	NUM	_	NumType=Card	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	infection	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	as	_	SCONJ	_	_	_	_	_	_
22	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
23	matured	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	into	_	ADP	_	_	_	_	_	_
25	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
29	over	_	ADV	_	_	_	_	_	_
30	7	_	NUM	_	NumType=Card	_	_	_	_
31	days	_	NOUN	_	Number=Plur	_	_	_	_
32	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	using	_	VERB	_	VerbForm=Ger	_	_	_	_
35	HIV	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	BaL	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	low	_	ADJ	_	Degree=Pos	_	_	_	_
44	passage	_	NOUN	_	Number=Sing	_	_	_	_
45	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
46	strains	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	13	_	NUM	_	NumType=Card	_	_	_	_
8	up	_	ADP	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	spliced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	HIV	_	PROPN	_	Number=Sing	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
22	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	Teflon	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	as	_	SCONJ	_	_	_	_	_	_
27	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
30	analysis	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	p24	_	PROPN	_	Number=Sing	_	_	_	_
33	Ag	_	PROPN	_	Number=Sing	_	_	_	_
34	assay	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	run	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	assay	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	two	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	threefold	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	translocation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	before	_	ADP	_	_	_	_	_	_
14	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	HIV	_	PROPN	_	Number=Sing	_	_	_	_
17	RNA	_	PROPN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Conversely	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	4	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	13	_	NUM	_	NumType=Card	_	_	_	_
10	markedly	_	ADV	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	significantly	_	ADV	_	_	_	_	_	_
13	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	HIV	_	PROPN	_	Number=Sing	_	_	_	_
15	replication	_	NOUN	_	Number=Sing	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
19	level	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
28	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	whether	_	SCONJ	_	_	_	_	_	_
30	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
31	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
32	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	added	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	before	_	ADP	_	_	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	after	_	ADP	_	_	_	_	_	_
37	HIV	_	NOUN	_	Number=Sing	_	_	_	_
38	infection	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	reversal	_	NOUN	_	Number=Sing	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
7	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	after	_	ADP	_	_	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	5	_	NUM	_	NumType=Card	_	_	_	_
12	days	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	adherence	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	plastic	_	ADJ	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	no	_	DET	_	_	_	_	_	_
6	significant	_	ADJ	_	Degree=Pos	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	reverse	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	both	_	DET	_	_	_	_	_	_
5	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
9	maturation	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	CD13	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	CD26	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	other	_	ADJ	_	Degree=Pos	_	_	_	_
22	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
23	markers	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	CD14	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	CD68	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	CD11b	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	but	_	CCONJ	_	_	_	_	_	_
8	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	CD26	_	PROPN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
13	CD13	_	PROPN	_	Number=Sing	_	_	_	_
14	loss	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	13	_	NUM	_	NumType=Card	_	_	_	_
4	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	similar	_	ADJ	_	Degree=Pos	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	CD13	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	no	_	DET	_	_	_	_	_	_
14	effect	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	CD26	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Hence	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
5	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	simply	_	ADV	_	_	_	_	_	_
8	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
9	monocyte	_	NOUN	_	Degree=Pos	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	complex	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	slightly	_	ADV	_	_	_	_	_	_
17	divergent	_	ADJ	_	Degree=Pos	_	_	_	_
18	effects	_	NOUN	_	Number=Plur	_	_	_	_
19	that	_	DET	_	_	_	_	_	_
20	impact	_	NOUN	_	Number=Sing	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	replication	_	NOUN	_	Number=Sing	_	_	_	_
24	probably	_	ADV	_	_	_	_	_	_
25	through	_	ADP	_	_	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	signaling	_	NOUN	_	Number=Sing	_	_	_	_
28	pathways	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	translocation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300155	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	localization	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	ETS	_	NOUN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	Elf	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Elf	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	belongs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	ETS	_	NOUN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	family	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	can	_	AUX	_	VerbForm=Fin	_	_	_	_
3	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	target	_	NOUN	_	Number=Sing	_	_	_	_
7	sequences	_	NOUN	_	Number=Plur	_	_	_	_
8	within	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	variety	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	cytokine	_	ADJ	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	Elf	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	constitutively	_	ADV	_	_	_	_	_	_
9	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	presence	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	amino	_	PROPN	_	Number=Sing	_	_	_	_
21	acids	_	NOUN	_	Number=Plur	_	_	_	_
22	86	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	265	_	NUM	_	NumType=Card	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Gal4	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	Elf	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	fusion	_	NOUN	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	N-	_	PROPN	_	Number=Sing	_	_	_	_
14	terminal	_	NOUN	_	Number=Sing	_	_	_	_
15	86	_	NUM	_	NumType=Card	_	_	_	_
16	amino	_	NOUN	_	Number=Sing	_	_	_	_
17	acids	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	Elf	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	domain	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	which	_	PRON	_	PronType=Rel	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	attenuated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	internal	_	ADJ	_	Degree=Pos	_	_	_	_
37	repression	_	NOUN	_	Number=Sing	_	_	_	_
38	domain	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Elf	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	interacts	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	specifically	_	ADV	_	_	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	E74	_	NUM	_	Number=Sing	_	_	_	_
11	target	_	NOUN	_	Number=Sing	_	_	_	_
12	sequence	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	E74	_	NUM	_	Number=Sing	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	independent	_	ADJ	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
25	signaling	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_

1	Elf	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	able	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	development	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300156	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Reactive	_	ADJ	_	Degree=Pos	_	_	_	_
2	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
3	intermediate	_	ADJ	_	Degree=Pos	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	release	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	fibre	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	increases	_	VERB	_	Number=Plur	_	_	_	_
12	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
16	level	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	co-cultured	_	VERB	_	Degree=Pos	_	_	_	_
28	bronchial	_	ADJ	_	Degree=Pos	_	_	_	_
29	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	BEAS	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2B	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Some	_	DET	_	_	_	_	_	_
2	pulmonary	_	ADJ	_	Degree=Pos	_	_	_	_
3	diseases	_	NOUN	_	Number=Plur	_	_	_	_
4	like	_	ADP	_	_	_	_	_	_
5	bronchitis	_	NOUN	_	Number=Sing	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	asthma	_	NOUN	_	Number=Sing	_	_	_	_
8	bronchiale	_	NOUN	_	Number=Sing	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	bronchial	_	ADJ	_	Degree=Pos	_	_	_	_
16	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
2	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	directly	_	ADV	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	surrounding	_	NOUN	_	VerbForm=Ger	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	so	_	SCONJ	_	_	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	suppose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	interaction	_	NOUN	_	Number=Sing	_	_	_	_
19	between	_	ADP	_	_	_	_	_	_
20	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
24	regarding	_	VERB	_	VerbForm=Ger	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	release	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
30	mediators	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	For	_	SCONJ	_	_	_	_	_	_
2	measuring	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	contribution	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	release	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	mediators	_	NOUN	_	Number=Plur	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	bronchial	_	ADJ	_	Degree=Pos	_	_	_	_
15	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	established	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	vitro	_	NOUN	_	Number=Sing	_	_	_	_
23	model	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	co-cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	blood	_	NOUN	_	Number=Sing	_	_	_	_
27	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	BM	_	PROPN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	BEAS	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2B	_	NUM	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	transwell	_	ADJ	_	Number=Sing	_	_	_	_
39	system	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	Costar	_	PROPN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	BM	_	PROPN	_	Number=Sing	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	exposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	Chrysotile	_	PROPN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	soot	_	NOUN	_	Number=Sing	_	_	_	_
9	particle	_	NOUN	_	Number=Sing	_	_	_	_
10	FR	_	ADP	_	Number=Sing	_	_	_	_
11	101	_	NUM	_	NumType=Card	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	concentration	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	100	_	NUM	_	NumType=Card	_	_	_	_
17	microg	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	10	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	6	_	NUM	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	up	_	ADP	_	_	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	90	_	NUM	_	NumType=Card	_	_	_	_
5	min	_	NOUN	_	Number=Plur	_	_	_	_
6	exposure	_	NOUN	_	Number=Sing	_	_	_	_
7	time	_	NOUN	_	Number=Sing	_	_	_	_
8	ELISA	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	electromobility	_	NOUN	_	Number=Sing	_	_	_	_
13	shift	_	NOUN	_	Number=Sing	_	_	_	_
14	assay	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	RT	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	PCR	_	NOUN	_	Number=Sing	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	measure	_	VERB	_	VerbForm=Inf	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
26	kinase	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	IL	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1beta	_	PROPN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	6	_	NUM	_	NumType=Card	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	TNF	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	alpha	_	NOUN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	specific	_	ADJ	_	Degree=Pos	_	_	_	_
51	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
52	levels	_	NOUN	_	Number=Plur	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	BEAS	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	2B	_	PROPN	_	Number=Sing	_	_	_	_
57	cells	_	NOUN	_	Number=Plur	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	increase	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	up	_	ADP	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	1.8	_	NUM	_	NumType=Card	_	_	_	_
14	+/-	_	SYM	_	_	_	_	_	_
15	0.5	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	fold	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	NF	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	BEAS	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2B	_	NUM	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	after	_	ADP	_	_	_	_	_	_
31	particle	_	NOUN	_	Number=Sing	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	fibre	_	VERB	_	Degree=Pos	_	_	_	_
34	exposure	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	co-cultured	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
37	BM.	_	PROPN	_	Number=Sing	_	_	_	_
38	Consecutive	_	ADJ	_	Degree=Pos	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1beta	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	IL	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	6	_	NUM	_	NumType=Card	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	TNF	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	alpha-mRNA	_	NOUN	_	Number=Sing	_	_	_	_
52	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
53	elevated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
54	(	_	PUNCT	_	_	_	_	_	_
55	up	_	ADP	_	_	_	_	_	_
56	to	_	ADP	_	_	_	_	_	_
57	1.9	_	NUM	_	NumType=Card	_	_	_	_
58	+/-	_	SYM	_	_	_	_	_	_
59	0.58	_	NUM	_	NumType=Card	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	fold	_	NOUN	_	Number=Sing	_	_	_	_
62	)	_	PUNCT	_	_	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
3	kinase	_	NOUN	_	Number=Sing	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	ROI	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	NF	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	bronchial	_	ADJ	_	Degree=Pos	_	_	_	_
18	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300158	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
9	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	MNDA	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
7	antigen	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	interferon	_	NOUN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	only	_	ADV	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
24	lineage	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
3	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
4	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	lineage	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	interferon	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	5	_	NUM	_	NumType=Card	_	_	_	_
18	'	_	PUNCT	_	_	_	_	_	_
19	flanking	_	NOUN	_	Degree=Pos	_	_	_	_
20	sequence	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	interferon	_	NOUN	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	response	_	NOUN	_	Number=Sing	_	_	_	_
6	elements	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	ISRE	_	X	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	flank	_	VERB	_	Number=Sing	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	start	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	identifying	_	VERB	_	VerbForm=Ger	_	_	_	_
18	MNDA	_	PROPN	_	Number=Sing	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	TATA	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	less	_	ADJ	_	Degree=Cmp	_	_	_	_
24	interferon	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Other	_	ADJ	_	Degree=Pos	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	elements	_	NOUN	_	Number=Plur	_	_	_	_
4	present	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	cluster	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Myb	_	NOUN	_	Number=Sing	_	_	_	_
10	sites	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	several	_	ADJ	_	Degree=Pos	_	_	_	_
13	Ets	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	Ets	_	NOUN	_	Number=Sing	_	_	_	_
17	related	_	ADJ	_	Degree=Pos	_	_	_	_
18	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	within	_	ADP	_	_	_	_	_	_
26	600	_	NUM	_	NumType=Card	_	_	_	_
27	bp	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	start	_	NOUN	_	Number=Sing	_	_	_	_
32	sites	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	methylation	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	revealed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	one	_	NUM	_	NumType=Card	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	possible	_	ADJ	_	Degree=Pos	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	SCONJ	_	_	_	_	_	_
15	establishing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	MNDA	_	PROPN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	5	_	NUM	_	NumType=Card	_	_	_	_
3	'	_	PUNCT	_	_	_	_	_	_
4	flanking	_	NOUN	_	Number=Sing	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	promoter	_	NOUN	_	Tense=Past|VerbForm=Part	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	elevated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	interferon	_	NOUN	_	Number=Sing	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	MNDA	_	PROPN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
11	similar	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	other	_	ADJ	_	Degree=Pos	_	_	_	_
14	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	up	_	ADP	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	interferon	_	NOUN	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300160	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Mycobacterium	_	PROPN	_	Number=Sing	_	_	_	_
2	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
3	mannose	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	capped	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	lipoarabinomannan	_	NOUN	_	Number=Sing	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	type	_	NOUN	_	Number=Sing	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	long	_	ADJ	_	Degree=Pos	_	_	_	_
22	terminal	_	NOUN	_	Number=Sing	_	_	_	_
23	repeat	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	T	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Tuberculosis	_	PROPN	_	Number=Sing	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	emerged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	epidemic	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	extended	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	large	_	ADJ	_	Degree=Pos	_	_	_	_
12	number	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	individuals	_	NOUN	_	Number=Plur	_	_	_	_
15	infected	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
19	virus	_	NOUN	_	Number=Sing	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	HIV	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	major	_	ADJ	_	Degree=Pos	_	_	_	_
3	goal	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	study	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
10	whether	_	SCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	mycobacterial	_	ADJ	_	Degree=Pos	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	wall	_	NOUN	_	Number=Sing	_	_	_	_
15	component	_	NOUN	_	Number=Sing	_	_	_	_
16	mannose	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	capped	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	lipoarabinomannan	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	ManLAM	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	Mycobacterium	_	PROPN	_	Number=Sing	_	_	_	_
25	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	M.	_	PROPN	_	Number=Sing	_	_	_	_
28	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	could	_	AUX	_	VerbForm=Fin	_	_	_	_
31	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	HIV	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	T	_	PROPN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	use	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	vitro	_	NOUN	_	Degree=Pos	_	_	_	_
47	cell	_	NOUN	_	Number=Sing	_	_	_	_
48	culture	_	NOUN	_	Number=Sing	_	_	_	_
49	system	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	prime	_	ADJ	_	Degree=Pos	_	_	_	_
6	importance	_	NOUN	_	Number=Sing	_	_	_	_
7	considering	_	VERB	_	VerbForm=Ger	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	CD4	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	represent	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	major	_	ADJ	_	Degree=Pos	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	reservoir	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
22	blood	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	infected	_	VERB	_	Degree=Pos	_	_	_	_
25	individuals	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	1G5	_	NUM	_	NumType=Card	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	line	_	NOUN	_	Number=Sing	_	_	_	_
6	harbouring	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
9	reporter	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	under	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	control	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	HIV	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	LTR	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	first	_	ADV	_	_	_	_	_	_
24	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	culture	_	NOUN	_	Number=Sing	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	filtrates	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	CFP	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	M.	_	PROPN	_	Number=Sing	_	_	_	_
34	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	ManLAM	_	NOUN	_	Number=Sing	_	_	_	_
38	could	_	AUX	_	VerbForm=Fin	_	_	_	_
39	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
40	HIV	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	LTR	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
46	gene	_	NOUN	_	Number=Sing	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	unlike	_	ADP	_	_	_	_	_	_
49	similarly	_	ADV	_	_	_	_	_	_
50	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	CFP	_	NOUN	_	Number=Sing	_	_	_	_
52	extracts	_	NOUN	_	Number=Plur	_	_	_	_
53	devoid	_	ADJ	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	ManLAM	_	PROPN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	implication	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	s	_	X	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	A	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	kinase	_	NOUN	_	Number=Sing	_	_	_	_
19	C	_	PROPN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	highlighted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	abrogation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	ManLAM	_	ADJ	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	HIV	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	LTR	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	using	_	VERB	_	VerbForm=Ger	_	_	_	_
41	herbimycin	_	NOUN	_	Number=Sing	_	_	_	_
42	A	_	PROPN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	H7	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	determined	_	ADJ	_	Degree=Pos	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	using	_	VERB	_	VerbForm=Ger	_	_	_	_
7	electrophoresis	_	NOUN	_	Degree=Pos	_	_	_	_
8	mobility	_	NOUN	_	Number=Sing	_	_	_	_
9	shift	_	NOUN	_	Number=Sing	_	_	_	_
10	assays	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	M.	_	PROPN	_	Number=Sing	_	_	_	_
14	tuberculosis	_	PROPN	_	Number=Sing	_	_	_	_
15	ManLAM	_	PROPN	_	Number=Sing	_	_	_	_
16	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	translocation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	M.	_	PROPN	_	Number=Sing	_	_	_	_
2	tuberculosis	_	PROPN	_	Number=Sing	_	_	_	_
3	ManLAM	_	PROPN	_	Number=Sing	_	_	_	_
4	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	clear	_	ADJ	_	Degree=Pos	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	placed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	under	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	control	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	wild	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	not	_	ADV	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	HIV	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	LTR	_	NOUN	_	Number=Sing	_	_	_	_
33	region	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	ManLAM	_	ADJ	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	LTR	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	independent	_	ADJ	_	Degree=Pos	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	autocrine	_	NOUN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	paracrine	_	NOUN	_	Number=Sing	_	_	_	_
24	action	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
27	TNF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	M.	_	PROPN	_	Number=Sing	_	_	_	_
6	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	upregulate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	could	_	AUX	_	VerbForm=Fin	_	_	_	_
18	thus	_	ADV	_	_	_	_	_	_
19	have	_	VERB	_	VerbForm=Inf	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	potential	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	HIV	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	infection	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300166	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	[	_	PUNCT	_	_	_	_	_	_
2	Corticoids	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	allergy	_	NOUN	_	Number=Sing	_	_	_	_
5	]	_	PUNCT	_	_	_	_	_	_

1	Inflammation	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	constantly	_	ADV	_	_	_	_	_	_
4	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	allergic	_	ADJ	_	Degree=Pos	_	_	_	_
7	reactions	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Corticosteroids	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	most	_	ADV	_	_	_	_	_	_
4	effective	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	SCONJ	_	_	_	_	_	_
6	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	late	_	ADJ	_	Degree=Pos	_	_	_	_
9	phase	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	allergic	_	ADJ	_	Degree=Pos	_	_	_	_
12	reaction	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	action	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	glucocorticosteroids	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	through	_	ADP	_	_	_	_	_	_
8	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
9	receptors	_	NOUN	_	Number=Plur	_	_	_	_
10	present	_	VERB	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
14	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
5	receptors	_	NOUN	_	Number=Plur	_	_	_	_
6	form	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	dimer	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	bind	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	after	_	ADP	_	_	_	_	_	_
14	migration	_	NOUN	_	Number=Sing	_	_	_	_
15	into	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Interaction	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	changes	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	rate	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	either	_	CCONJ	_	_	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	repression	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
2	receptors	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	able	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	such	_	ADJ	_	Degree=Pos	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	activator	_	NOUN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Through	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	actions	_	NOUN	_	Number=Plur	_	_	_	_
4	glucocorticosteroids	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	susceptible	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	modify	_	VERB	_	VerbForm=Inf	_	_	_	_
9	functions	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	involved	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	allergic	_	ADJ	_	Degree=Pos	_	_	_	_
16	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	particular	_	ADJ	_	Degree=Pos	_	_	_	_
5	able	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
8	most	_	ADJ	_	Degree=Sup	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	pro-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	functions	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300167	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Alpha	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	lipoic	_	PROPN	_	Number=Sing	_	_	_	_
4	acid	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	potent	_	ADJ	_	Degree=Pos	_	_	_	_
8	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Acquired	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	results	_	NOUN	_	Number=Plur	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	infection	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	long	_	ADJ	_	Degree=Pos	_	_	_	_
3	terminal	_	NOUN	_	Number=Sing	_	_	_	_
4	repeat	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	LTR	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	region	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
12	DNA	_	NOUN	_	Number=Sing	_	_	_	_
13	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	binding	_	NOUN	_	VerbForm=Ger	_	_	_	_
15	sites	_	NOUN	_	Number=Plur	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	PROPN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
31	activator	_	NOUN	_	Number=Sing	_	_	_	_
32	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
35	HIV	_	NOUN	_	Number=Sing	_	_	_	_
36	activation	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	involvement	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
8	oxygen	_	ADJ	_	Degree=Pos	_	_	_	_
9	species	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	ROS	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	signal	_	ADJ	_	Number=Sing	_	_	_	_
15	transduction	_	NOUN	_	Number=Sing	_	_	_	_
16	pathways	_	NOUN	_	Number=Plur	_	_	_	_
17	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	reports	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	eliminate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	ROS	_	NOUN	_	Number=Sing	_	_	_	_
13	should	_	AUX	_	VerbForm=Fin	_	_	_	_
14	block	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	subsequently	_	ADV	_	_	_	_	_	_
24	HIV	_	NOUN	_	Number=Sing	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	thus	_	ADV	_	_	_	_	_	_
29	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
30	can	_	AUX	_	VerbForm=Fin	_	_	_	_
31	be	_	AUX	_	VerbForm=Inf	_	_	_	_
32	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	as	_	ADP	_	_	_	_	_	_
34	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
35	agents	_	NOUN	_	Number=Plur	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Incubation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	x	_	SYM	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	6	_	NUM	_	NumType=Card	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	ml	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	natural	_	ADJ	_	Degree=Pos	_	_	_	_
20	thiol	_	NOUN	_	Number=Sing	_	_	_	_
21	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	lipoic	_	NOUN	_	Number=Sing	_	_	_	_
26	acid	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	prior	_	ADJ	_	Degree=Pos	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
35	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	kappa	_	NOUN	_	Number=Sing	_	_	_	_
41	B	_	NOUN	_	Number=Sing	_	_	_	_
42	activation	_	NOUN	_	Number=Sing	_	_	_	_
43	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	by	_	ADP	_	_	_	_	_	_
45	tumor	_	NOUN	_	Number=Sing	_	_	_	_
46	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
47	factor	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	alpha	_	NOUN	_	Number=Sing	_	_	_	_
50	(	_	PUNCT	_	_	_	_	_	_
51	25	_	NUM	_	NumType=Card	_	_	_	_
52	ng	_	NOUN	_	Number=Sing	_	_	_	_
53	/	_	PUNCT	_	_	_	_	_	_
54	ml	_	NOUN	_	Number=Sing	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	or	_	CCONJ	_	_	_	_	_	_
57	by	_	ADP	_	_	_	_	_	_
58	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
59	12	_	NUM	_	NumType=Card	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	myristate	_	NOUN	_	Number=Sing	_	_	_	_
62	13	_	NUM	_	NumType=Card	_	_	_	_
63	-	_	PUNCT	_	_	_	_	_	_
64	acetate	_	NOUN	_	Number=Sing	_	_	_	_
65	(	_	PUNCT	_	_	_	_	_	_
66	50	_	NUM	_	NumType=Card	_	_	_	_
67	ng	_	NOUN	_	Number=Sing	_	_	_	_
68	/	_	SYM	_	_	_	_	_	_
69	ml	_	NOUN	_	Number=Sing	_	_	_	_
70	)	_	PUNCT	_	_	_	_	_	_
71	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
3	action	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	lipoic	_	NOUN	_	Number=Sing	_	_	_	_
8	acid	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	very	_	ADV	_	_	_	_	_	_
14	potent	_	ADJ	_	Degree=Pos	_	_	_	_
15	as	_	ADV	_	_	_	_	_	_
16	only	_	ADV	_	_	_	_	_	_
17	4	_	NUM	_	NumType=Card	_	_	_	_
18	mM	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	needed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	complete	_	ADJ	_	Degree=Pos	_	_	_	_
24	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	whereas	_	SCONJ	_	_	_	_	_	_
27	20	_	NUM	_	NumType=Card	_	_	_	_
28	mM	_	NOUN	_	Number=Sing	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	N	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	acetylcysteine	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	lipoic	_	NOUN	_	Number=Sing	_	_	_	_
8	acid	_	NOUN	_	Number=Sing	_	_	_	_
9	may	_	AUX	_	VerbForm=Fin	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	effective	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
14	therapeutics	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300168	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Effects	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	glucocorticoids	_	NOUN	_	Number=Sing	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
11	blood	_	NOUN	_	Number=Sing	_	_	_	_
12	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
2	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	immune	_	ADJ	_	Degree=Pos	_	_	_	_
10	responses	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	modulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	DNA	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	interaction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	activator	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
32	element	_	NOUN	_	Number=Sing	_	_	_	_
33	binding	_	VERB	_	Number=Sing	_	_	_	_
34	protein	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	CREB	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	DNA	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
42	receptors	_	NOUN	_	Number=Plur	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	GR	_	NOUN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
47	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	human	_	ADJ	_	Degree=Pos	_	_	_	_
50	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
51	blood	_	NOUN	_	Number=Sing	_	_	_	_
52	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
53	cells	_	NOUN	_	Number=Plur	_	_	_	_
54	by	_	ADP	_	_	_	_	_	_
55	gel	_	NOUN	_	Number=Sing	_	_	_	_
56	mobility	_	NOUN	_	Number=Sing	_	_	_	_
57	shift	_	NOUN	_	Number=Sing	_	_	_	_
58	assays	_	NOUN	_	Number=Plur	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	beta	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
11	myristate	_	PROPN	_	Number=Sing	_	_	_	_
12	acetate	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	PMA	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	treatment	_	NOUN	_	Number=Sing	_	_	_	_
17	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	DNA	_	PROPN	_	Number=Sing	_	_	_	_
26	binding	_	VERB	_	Number=Sing	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	up	_	ADP	_	_	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	200	_	NUM	_	NumType=Card	_	_	_	_
31	%	_	SYM	_	Number=Sing	_	_	_	_
32	but	_	CCONJ	_	_	_	_	_	_
33	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	CREB	_	NOUN	_	Number=Sing	_	_	_	_
35	binding	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	38	_	NUM	_	NumType=Card	_	_	_	_
38	%	_	SYM	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	over	_	ADP	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	60	_	NUM	_	NumType=Card	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	min	_	NOUN	_	NumType=Card	_	_	_	_
45	time	_	NOUN	_	Number=Sing	_	_	_	_
46	course	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Dexamethasone	_	PROPN	_	Number=Sing	_	_	_	_
2	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	increase	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	element	_	NOUN	_	Number=Sing	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
16	40	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	50	_	NUM	_	NumType=Card	_	_	_	_
19	%	_	SYM	_	Number=Sing	_	_	_	_
20	decrease	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	AP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	CREB	_	PROPN	_	Number=Sing	_	_	_	_
32	DNA	_	PROPN	_	Number=Sing	_	_	_	_
33	binding	_	NOUN	_	Number=Sing	_	_	_	_
34	that	_	PRON	_	PronType=Rel	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
42	or	_	CCONJ	_	_	_	_	_	_
43	PMA	_	NOUN	_	Number=Sing	_	_	_	_
44	treatment	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	latter	_	ADJ	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	due	_	ADP	_	_	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	increases	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	localization	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	GR	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	amounts	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	other	_	ADJ	_	Degree=Pos	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	GR	_	NOUN	_	Number=Sing	_	_	_	_
8	within	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	nucleus	_	ADJ	_	Number=Sing	_	_	_	_
11	interacts	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	process	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	cross	_	NOUN	_	Number=Sing	_	_	_	_
23	coupling	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	be	_	AUX	_	VerbForm=Inf	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
10	action	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300178	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Helenalin	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	sesquiterpene	_	NOUN	_	Number=Sing	_	_	_	_
6	lactone	_	NOUN	_	Number=Sing	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	Arnica	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	selectively	_	ADV	_	_	_	_	_	_
11	inhibits	_	VERB	_	Degree=Pos	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	[	_	PUNCT	_	_	_	_	_	_
18	see	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
19	comments	_	NOUN	_	Number=Plur	_	_	_	_
20	]	_	PUNCT	_	_	_	_	_	_

1	Alcoholic	_	ADJ	_	Degree=Pos	_	_	_	_
2	extracts	_	NOUN	_	Number=Plur	_	_	_	_
3	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	form	_	NOUN	_	Number=Sing	_	_	_	_
5	Arnicae	_	PROPN	_	Number=Sing	_	_	_	_
6	flos	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	collective	_	ADJ	_	Degree=Pos	_	_	_	_
10	name	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	flowerheads	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	Arnica	_	PROPN	_	Number=Sing	_	_	_	_
15	montana	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	A.	_	PROPN	_	Number=Sing	_	_	_	_
18	chamissonis	_	PROPN	_	Number=Sing	_	_	_	_
19	ssp	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	foliosa	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	therapeutically	_	ADV	_	_	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	remedies	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	active	_	ADJ	_	Degree=Pos	_	_	_	_
3	ingredients	_	NOUN	_	Number=Plur	_	_	_	_
4	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	pharmacological	_	ADJ	_	Degree=Pos	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	mainly	_	ADV	_	_	_	_	_	_
10	sesquiterpene	_	ADJ	_	Degree=Pos	_	_	_	_
11	lactones	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	such	_	ADJ	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	helenalin	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	11alpha	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	13	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	dihydrohelenalin	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	chamissonolid	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	ester	_	NOUN	_	Number=Sing	_	_	_	_
27	derivatives	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	compounds	_	NOUN	_	Number=Plur	_	_	_	_
4	affect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	various	_	ADJ	_	Degree=Pos	_	_	_	_
6	cellular	_	ADJ	_	Number=Sing	_	_	_	_
7	processes	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	current	_	ADJ	_	Degree=Pos	_	_	_	_
10	data	_	NOUN	_	Number=Sing	_	_	_	_
11	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	fully	_	ADV	_	_	_	_	_	_
14	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
15	how	_	ADV	_	PronType=Int	_	_	_	_
16	sesquiterpene	_	ADJ	_	Degree=Pos	_	_	_	_
17	lactones	_	NOUN	_	Number=Plur	_	_	_	_
18	exert	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	anti	_	X	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	effect	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	helenalin	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	much	_	ADV	_	_	_	_	_	_
12	lesser	_	ADJ	_	Degree=Cmp	_	_	_	_
13	degree	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	11alpha,13	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	dihydrohelenalin	_	ADJ	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	chamissonolid	_	ADJ	_	Degree=Pos	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	inhibit	_	VERB	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	difference	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	efficacy	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	compounds	_	NOUN	_	Number=Plur	_	_	_	_
11	'	_	PART	_	_	_	_	_	_
12	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	potency	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	vivo	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	explained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	differences	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	structure	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	conformation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	resides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
12	complex	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	degradation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
26	subunit	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Helenalin	_	PROPN	_	_	_	_	_	_
2	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	response	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	four	_	NUM	_	NumType=Card	_	_	_	_
11	different	_	ADJ	_	Degree=Pos	_	_	_	_
12	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	abrogates	_	VERB	_	Degree=Pos	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	selective	_	ADJ	_	Degree=Pos	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	four	_	NUM	_	NumType=Card	_	_	_	_
11	other	_	ADJ	_	Degree=Pos	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	Oct	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	TBP	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	STAT	_	PROPN	_	Number=Sing	_	_	_	_
24	5	_	NUM	_	NumType=Card	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	due	_	ADP	_	_	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	direct	_	ADJ	_	Degree=Pos	_	_	_	_
11	modification	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	active	_	ADJ	_	Degree=Pos	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Rather	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	helenalin	_	ADV	_	Number=Sing	_	_	_	_
4	modifies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
11	complex	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	release	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	effect	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	sesquiterpene	_	ADJ	_	Number=Sing	_	_	_	_
13	lactones	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	differs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	other	_	ADJ	_	Degree=Pos	_	_	_	_
21	nonsteroidal	_	ADJ	_	Degree=Pos	_	_	_	_
22	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	drugs	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	NSAIDs	_	NOUN	_	Number=Plur	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	indomethacin	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	acetyl	_	ADJ	_	Number=Sing	_	_	_	_
31	salicylic	_	ADJ	_	Degree=Pos	_	_	_	_
32	acid	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300181	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Competent	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	initiation	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	RNA	_	PROPN	_	Number=Sing	_	_	_	_
6	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
7	II	_	NUM	_	NumType=Card	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	free	_	ADJ	_	Degree=Pos	_	_	_	_
12	extracts	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	xeroderma	_	NOUN	_	Number=Sing	_	_	_	_
15	pigmentosum	_	NOUN	_	Number=Sing	_	_	_	_
16	groups	_	NOUN	_	Number=Plur	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	D	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	optimized	_	ADJ	_	Degree=Pos	_	_	_	_
23	RNA	_	PROPN	_	Number=Sing	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	assay	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	autosomal	_	ADJ	_	Number=Sing	_	_	_	_
4	recessive	_	ADJ	_	Degree=Pos	_	_	_	_
5	disease	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	xeroderma	_	NOUN	_	Number=Sing	_	_	_	_
8	pigmentosum	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	XP	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	can	_	AUX	_	VerbForm=Fin	_	_	_	_
14	result	_	VERB	_	VerbForm=Inf	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	mutations	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	any	_	DET	_	_	_	_	_	_
19	one	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	seven	_	NUM	_	NumType=Card	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	XPA	_	NOUN	_	Number=Sing	_	_	_	_
26	through	_	ADP	_	_	_	_	_	_
27	XPG	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Of	_	ADP	_	_	_	_	_	_
2	these	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	XPB	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	XPD	_	NOUN	_	Number=Sing	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	encode	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	subunits	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	general	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	TFIIH	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	involved	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	both	_	DET	_	_	_	_	_	_
25	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
26	excision	_	NOUN	_	Number=Sing	_	_	_	_
27	repair	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	NER	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	initiation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	RNA	_	PROPN	_	Number=Sing	_	_	_	_
38	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
39	II	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	humans	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	mutation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	XPB	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	XPD	_	PROPN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	impairs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	NER	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	hyper	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	sunlight	_	VERB	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	greatly	_	ADV	_	_	_	_	_	_
23	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	skin	_	NOUN	_	Number=Sing	_	_	_	_
25	tumor	_	NOUN	_	Number=Sing	_	_	_	_
26	formation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	either	_	CCONJ	_	_	_	_	_	_
11	XP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	XP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	D	_	PROPN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	employed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	optimized	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	free	_	ADJ	_	Degree=Pos	_	_	_	_
9	RNA	_	NOUN	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	assay	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	XP	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	XP	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	D.	_	PROPN	_	Number=Sing	_	_	_	_
24	Although	_	SCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	growth	_	NOUN	_	Number=Sing	_	_	_	_
27	rate	_	NOUN	_	Number=Sing	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	normal	_	ADJ	_	Degree=Pos	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	XP	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	XP	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	D	_	NOUN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	amounts	_	NOUN	_	Number=Plur	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	TFIIH	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Extracts	_	NOUN	_	Number=Plur	_	_	_	_
2	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	XP	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	XP	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	D	_	PROPN	_	Number=Sing	_	_	_	_
11	lymphoblastoid	_	VERB	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	exhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	similar	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	adenovirus	_	NOUN	_	Degree=Pos	_	_	_	_
20	major	_	ADJ	_	Degree=Pos	_	_	_	_
21	late	_	ADJ	_	Degree=Pos	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	when	_	ADV	_	PronType=Int	_	_	_	_
24	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	extracts	_	NOUN	_	Number=Plur	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	normal	_	ADJ	_	Degree=Pos	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	XP	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	XP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	D	_	PROPN	_	Number=Sing	_	_	_	_
14	lymphoblastoid	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	have	_	AUX	_	VerbForm=Inf	_	_	_	_
19	impaired	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	RNA	_	PROPN	_	Number=Sing	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	consider	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	possible	_	ADJ	_	Degree=Pos	_	_	_	_
5	consequences	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	content	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	TFIIH	_	PROPN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
16	symptoms	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	XP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	XP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	D	_	NOUN	_	Number=Sing	_	_	_	_
25	patients	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	discuss	_	VERB	_	VerbForm=Inf	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	'	_	PUNCT	_	_	_	_	_	_
31	conditional	_	ADJ	_	Degree=Pos	_	_	_	_
32	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
33	'	_	PUNCT	_	_	_	_	_	_
34	that	_	PRON	_	PronType=Rel	_	_	_	_
35	may	_	AUX	_	VerbForm=Fin	_	_	_	_
36	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
37	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	impairment	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
41	function	_	NOUN	_	Number=Sing	_	_	_	_
42	only	_	ADV	_	_	_	_	_	_
43	under	_	ADP	_	_	_	_	_	_
44	certain	_	ADJ	_	Degree=Pos	_	_	_	_
45	growth	_	NOUN	_	Number=Sing	_	_	_	_
46	conditions	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300187	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	remodeling	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	globin	_	NOUN	_	Number=Sing	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
10	structure	_	NOUN	_	Number=Sing	_	_	_	_
11	produces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	silencing	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	chromatin	_	ADJ	_	Degree=Pos	_	_	_	_
3	structure	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	beta-globin	_	NOUN	_	Degree=Pos	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	locus	_	NOUN	_	Number=Sing	_	_	_	_
10	assumes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	transcriptionally	_	ADV	_	_	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	active	_	ADJ	_	Degree=Pos	_	_	_	_
15	conformation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	feature	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
6	reorganization	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	formation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	DNase	_	NOUN	_	Number=Sing	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
14	sites	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	regions	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	active	_	ADJ	_	Degree=Pos	_	_	_	_
20	globin	_	ADJ	_	Degree=Pos	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	promoters	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	reorganization	_	NOUN	_	Number=Sing	_	_	_	_
3	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	globin	_	ADJ	_	Degree=Pos	_	_	_	_
6	locus	_	NOUN	_	Number=Sing	_	_	_	_
7	control	_	NOUN	_	Number=Sing	_	_	_	_
8	region	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	normal	_	ADJ	_	Degree=Pos	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	beta	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	like	_	ADJ	_	Degree=Pos	_	_	_	_
20	globin	_	NOUN	_	Degree=Pos	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	possible	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	artificially	_	ADV	_	_	_	_	_	_
9	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	opening	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	chromatin	_	ADJ	_	Degree=Pos	_	_	_	_
15	structure	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	globin	_	NOUN	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
25	placed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	101bp	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	specific	_	ADJ	_	Degree=Pos	_	_	_	_
32	DNase	_	NOUN	_	Number=Sing	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
35	site	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
38	element	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	HSFE	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	immediately	_	ADV	_	_	_	_	_	_
43	upstream	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	beta	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	globin	_	NOUN	_	Degree=Pos	_	_	_	_
49	promoter	_	NOUN	_	Number=Sing	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	gene	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	element	_	NOUN	_	Number=Sing	_	_	_	_
3	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	sites	_	NOUN	_	Number=Plur	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	E2	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	GATA	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	Sp	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Constructs	_	NOUN	_	Number=Plur	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	stably	_	ADV	_	_	_	_	_	_
4	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	into	_	ADP	_	_	_	_	_	_
6	murine	_	NOUN	_	Number=Sing	_	_	_	_
7	erythroleukemia	_	ADJ	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	promoter	_	NOUN	_	Degree=Pos	_	_	_	_
11	chromatin	_	NOUN	_	Degree=Pos	_	_	_	_
12	structure	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	HSFE	_	NOUN	_	Number=Sing	_	_	_	_
3	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	area	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	DNase	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	hypersensitivity	_	NOUN	_	Number=Sing	_	_	_	_
11	extending	_	VERB	_	VerbForm=Ger	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	start	_	NOUN	_	Number=Sing	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	-	_	SYM	_	_	_	_	_	_
19	300	_	NUM	_	NumType=Card	_	_	_	_
20	bp	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	artificial	_	ADJ	_	Degree=Pos	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	significantly	_	ADV	_	_	_	_	_	_
27	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	proportion	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	beta	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	globin	_	NOUN	_	Degree=Pos	_	_	_	_
34	promoters	_	NOUN	_	Number=Plur	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	open	_	ADJ	_	Degree=Pos	_	_	_	_
38	chromatin	_	ADJ	_	Number=Sing	_	_	_	_
39	configuration	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	remodeling	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
6	structure	_	NOUN	_	Number=Sing	_	_	_	_
7	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	fold	_	NOUN	_	Number=Sing	_	_	_	_
12	increases	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	beta-globin	_	ADJ	_	Degree=Pos	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	long	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	term	_	NOUN	_	Number=Sing	_	_	_	_
25	beta-globin	_	NOUN	_	Degree=Pos	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	silencing	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	relatively	_	ADV	_	_	_	_	_	_
7	small	_	ADJ	_	Degree=Pos	_	_	_	_
8	cis	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	acting	_	NOUN	_	VerbForm=Ger	_	_	_	_
11	element	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	able	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
16	remodeling	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	promoter	_	NOUN	_	Degree=Pos	_	_	_	_
19	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
20	structure	_	NOUN	_	Number=Sing	_	_	_	_
21	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	beta	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	globin	_	ADJ	_	Degree=Pos	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300191	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	control	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	steroid	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	murine	_	ADJ	_	Number=Sing	_	_	_	_
10	thymoma	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Early	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	murine	_	NOUN	_	Number=Sing	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	lines	_	NOUN	_	Number=Plur	_	_	_	_
8	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
12	functions	_	NOUN	_	Number=Plur	_	_	_	_
13	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	GR	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	N	_	X	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
24	domain	_	NOUN	_	Number=Sing	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
31	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	more	_	ADV	_	_	_	_	_	_
4	recent	_	ADJ	_	Degree=Pos	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	lines	_	NOUN	_	Number=Plur	_	_	_	_
11	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	N	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	terminal	_	NOUN	_	Number=Sing	_	_	_	_
18	domain	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	steroid	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	GR	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	transrepression	_	NOUN	_	Number=Sing	_	_	_	_
33	may	_	AUX	_	VerbForm=Fin	_	_	_	_
34	be	_	AUX	_	VerbForm=Inf	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	more	_	ADV	_	_	_	_	_	_
37	critical	_	ADJ	_	Degree=Pos	_	_	_	_
38	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	better	_	ADV	_	Degree=Cmp	_	_	_	_
3	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	contribution	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	GR	_	PROPN	_	Number=Sing	_	_	_	_
9	N-terminal	_	ADJ	_	Number=Sing	_	_	_	_
10	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
11	domain	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	SCONJ	_	_	_	_	_	_
13	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	murine	_	NOUN	_	Number=Sing	_	_	_	_
15	thymocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	stably	_	ADV	_	_	_	_	_	_
20	transfected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	GR	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	GR	_	NOUN	_	Number=Sing	_	_	_	_
24	variants	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	androgen	_	NOUN	_	Degree=Pos	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	AR	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	into	_	ADP	_	_	_	_	_	_
34	receptor	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	negative	_	ADJ	_	Degree=Pos	_	_	_	_
37	S49	_	NOUN	_	Number=Sing	_	_	_	_
38	murine	_	NOUN	_	Number=Sing	_	_	_	_
39	thymoma	_	NOUN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	GR	_	NOUN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	rate	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	limiting	_	VERB	_	Degree=Pos	_	_	_	_
11	for	_	SCONJ	_	_	_	_	_	_
12	initiating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
15	pathway	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	positive	_	ADJ	_	Degree=Pos	_	_	_	_
20	correlation	_	NOUN	_	Number=Sing	_	_	_	_
21	between	_	ADP	_	_	_	_	_	_
22	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
23	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	GR	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	induction	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	integrated	_	ADJ	_	Degree=Pos	_	_	_	_
32	mouse	_	NOUN	_	Number=Sing	_	_	_	_
33	mammary	_	ADJ	_	Number=Sing	_	_	_	_
34	tumor	_	NOUN	_	Number=Sing	_	_	_	_
35	virus	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	MMTV	_	PROPN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	LTR	_	NOUN	_	Number=Sing	_	_	_	_
40	reporter	_	NOUN	_	Number=Sing	_	_	_	_
41	gene	_	NOUN	_	Number=Sing	_	_	_	_
42	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
43	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	GR	_	NOUN	_	Number=Sing	_	_	_	_
4	chimeric	_	ADJ	_	Number=Sing	_	_	_	_
5	receptors	_	NOUN	_	Number=Plur	_	_	_	_
6	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	potent	_	NOUN	_	Number=Sing	_	_	_	_
9	VP16	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	E1A	_	PROPN	_	Number=Sing	_	_	_	_
12	viral	_	ADJ	_	Degree=Pos	_	_	_	_
13	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
14	domains	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	place	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	GR	_	PROPN	_	Number=Sing	_	_	_	_
20	N	_	PROPN	_	Number=Sing	_	_	_	_
21	terminus	_	NOUN	_	Number=Sing	_	_	_	_
22	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	even	_	ADV	_	_	_	_	_	_
25	low	_	ADJ	_	Degree=Pos	_	_	_	_
26	level	_	NOUN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
30	receptors	_	NOUN	_	Number=Plur	_	_	_	_
31	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	both	_	DET	_	_	_	_	_	_
34	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	steroid	_	NOUN	_	Number=Sing	_	_	_	_
36	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	MMTV	_	NOUN	_	Number=Sing	_	_	_	_
39	induction	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	thus	_	ADV	_	_	_	_	_	_
42	supporting	_	VERB	_	VerbForm=Ger	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	role	_	NOUN	_	Number=Sing	_	_	_	_
45	for	_	ADP	_	_	_	_	_	_
46	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	AR	_	NOUN	_	Number=Sing	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	S49	_	NUM	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	after	_	ADP	_	_	_	_	_	_
15	treatment	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	5	_	NUM	_	NumType=Card	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	dihydrotestosterone	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	despite	_	ADP	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	relative	_	ADJ	_	Degree=Pos	_	_	_	_
25	inability	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
28	high	_	ADJ	_	Degree=Pos	_	_	_	_
29	level	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	MMTV	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
4	further	_	ADV	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	steroid	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
16	thymocyte	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	GIG18	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	GIG18	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	rapidly	_	ADV	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	AR	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	GR	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	AR	_	NOUN	_	Number=Sing	_	_	_	_
20	can	_	AUX	_	VerbForm=Fin	_	_	_	_
21	indeed	_	ADV	_	_	_	_	_	_
22	function	_	NOUN	_	VerbForm=Inf	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
26	activator	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	S49	_	NUM	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	moreover	_	ADV	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	that	_	SCONJ	_	_	_	_	_	_
35	GIG18	_	PROPN	_	Number=Sing	_	_	_	_
36	induction	_	NOUN	_	Number=Sing	_	_	_	_
37	may	_	AUX	_	VerbForm=Fin	_	_	_	_
38	be	_	AUX	_	VerbForm=Inf	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	marker	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	early	_	ADJ	_	Degree=Pos	_	_	_	_
43	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
44	events	_	NOUN	_	Number=Plur	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	steroid	_	ADJ	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	cells	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
8	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
15	signaling	_	NOUN	_	Number=Sing	_	_	_	_
16	component	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	S49	_	NUM	_	NumType=Card	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	although	_	SCONJ	_	_	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	additional	_	ADJ	_	Degree=Pos	_	_	_	_
25	role	_	NOUN	_	Number=Sing	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	GR	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	mediated	_	VERB	_	Degree=Pos	_	_	_	_
30	transrepression	_	NOUN	_	Number=Sing	_	_	_	_
31	can	_	AUX	_	VerbForm=Fin	_	_	_	_
32	not	_	PART	_	_	_	_	_	_
33	be	_	AUX	_	VerbForm=Inf	_	_	_	_
34	excluded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300192	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	RFLAT	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	new	_	ADJ	_	Degree=Pos	_	_	_	_
7	zinc	_	NOUN	_	Number=Sing	_	_	_	_
8	finger	_	NOUN	_	Number=Sing	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	RANTES	_	PROPN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	RANTES	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	Regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	upon	_	ADP	_	_	_	_	_	_
5	Activation	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	Normal	_	ADJ	_	Degree=Pos	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	Expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	chemoattractant	_	ADJ	_	Degree=Pos	_	_	_	_
17	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	important	_	ADJ	_	Degree=Pos	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	generation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	infiltrate	_	NOUN	_	Degree=Pos	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
31	virus	_	NOUN	_	Number=Sing	_	_	_	_
32	entry	_	NOUN	_	Number=Sing	_	_	_	_
33	into	_	ADP	_	_	_	_	_	_
34	immune	_	ADJ	_	Degree=Pos	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	RANTES	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	late	_	ADV	_	Degree=Pos	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	days	_	NOUN	_	Number=Plur	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	after	_	ADP	_	_	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	cloning	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
9	"	_	PUNCT	_	_	_	_	_	_
10	late	_	ADJ	_	Degree=Pos	_	_	_	_
11	"	_	PUNCT	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	lymphocyte	_	PROPN	_	Number=Sing	_	_	_	_
14	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	named	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
20	"	_	PUNCT	_	_	_	_	_	_
21	RANTES	_	PROPN	_	Number=Sing	_	_	_	_
22	Factor	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	Late	_	ADJ	_	Degree=Pos	_	_	_	_
25	Activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	T	_	PROPN	_	Number=Sing	_	_	_	_
27	Lymphocytes	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	"	_	PUNCT	_	_	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	RFLAT	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	RFLAT	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	novel	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	phosphorylated	_	VERB	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	zinc	_	NOUN	_	Number=Sing	_	_	_	_
11	finger	_	NOUN	_	Number=Sing	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	days	_	NOUN	_	Number=Plur	_	_	_	_
22	after	_	ADP	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	coincident	_	ADJ	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	RANTES	_	PROPN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	Rel	_	NOUN	_	Number=Sing	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	RANTES	_	PROPN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	RFLAT	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	strong	_	ADJ	_	Degree=Pos	_	_	_	_
21	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	RANTES	_	PROPN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	T	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300194	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Infection	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	replication	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Tat	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
9	viruses	_	NOUN	_	Number=Plur	_	_	_	_
10	:	_	PUNCT	_	_	_	_	_	_

1	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
2	analyses	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	LTR	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	tat	_	NOUN	_	Number=Sing	_	_	_	_
7	mutations	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	long	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	term	_	NOUN	_	Number=Sing	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Tat	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	essential	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	replication	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	tat	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	block	_	VERB	_	VerbForm=Inf	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	replication	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	Tat	_	PROPN	_	Number=Sing	_	_	_	_
7	releases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	elongation	_	NOUN	_	Number=Sing	_	_	_	_
10	block	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	long	_	ADJ	_	Degree=Pos	_	_	_	_
17	terminal	_	NOUN	_	Number=Sing	_	_	_	_
18	repeat	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	LTR	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	;	_	PUNCT	_	_	_	_	_	_
23	however	_	ADV	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	whether	_	SCONJ	_	_	_	_	_	_
30	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
32	alone	_	ADV	_	_	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	block	_	NOUN	_	Number=Sing	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	HIV	_	NOUN	_	Number=Sing	_	_	_	_
41	replication	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	human	_	ADJ	_	Degree=Pos	_	_	_	_
44	T	_	NOUN	_	Number=Sing	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	when	_	ADV	_	PronType=Int	_	_	_	_
47	Tat	_	PROPN	_	Number=Sing	_	_	_	_
48	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	absent	_	ADJ	_	Degree=Pos	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	possible	_	ADJ	_	Degree=Pos	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Tat	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	needed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	other	_	ADJ	_	Degree=Pos	_	_	_	_
11	functions	_	NOUN	_	Number=Plur	_	_	_	_
12	during	_	ADP	_	_	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	replication	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	test	_	VERB	_	VerbForm=Inf	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	hypotheses	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	several	_	ADJ	_	Degree=Pos	_	_	_	_
9	tat	_	NOUN	_	Number=Sing	_	_	_	_
10	mutants	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	including	_	VERB	_	VerbForm=Ger	_	_	_	_
13	two	_	NUM	_	NumType=Card	_	_	_	_
14	stop	_	NOUN	_	Number=Sing	_	_	_	_
15	codon	_	NOUN	_	Degree=Pos	_	_	_	_
16	mutants	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	one	_	NUM	_	NumType=Card	_	_	_	_
19	deletion	_	NOUN	_	Number=Sing	_	_	_	_
20	mutant	_	NOUN	_	Number=Sing	_	_	_	_
21	using	_	VERB	_	VerbForm=Ger	_	_	_	_
22	replication	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	competent	_	ADJ	_	Degree=Pos	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	constructs	_	NOUN	_	Number=Plur	_	_	_	_
29	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
30	wild	_	ADJ	_	Degree=Pos	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	type	_	NOUN	_	Number=Sing	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
35	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	modifications	_	NOUN	_	Number=Plur	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappa	_	NOUN	_	Number=Sing	_	_	_	_
43	B	_	NOUN	_	Number=Sing	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	/	_	PUNCT	_	_	_	_	_	_
46	or	_	CCONJ	_	_	_	_	_	_
47	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
48	binding	_	NOUN	_	Number=Sing	_	_	_	_
49	sites	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	Tat	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	HIV	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	wild	_	ADJ	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	type	_	NOUN	_	Number=Sing	_	_	_	_
17	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
18	can	_	AUX	_	VerbForm=Fin	_	_	_	_
19	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	virus	_	NOUN	_	Number=Sing	_	_	_	_
27	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	can	_	AUX	_	VerbForm=Fin	_	_	_	_
32	infect	_	VERB	_	VerbForm=Inf	_	_	_	_
33	primary	_	ADJ	_	Degree=Pos	_	_	_	_
34	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
35	blood	_	NOUN	_	Number=Sing	_	_	_	_
36	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	propagation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Tat	_	PROPN	_	Number=Sing	_	_	_	_
10	mutants	_	NOUN	_	Number=Plur	_	_	_	_
11	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	wild	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	type	_	NOUN	_	Number=Sing	_	_	_	_
15	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	less	_	ADV	_	Degree=Cmp	_	_	_	_
18	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
19	than	_	ADP	_	_	_	_	_	_
20	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	LTR	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	Tat	_	NOUN	_	Number=Sing	_	_	_	_
27	mutants	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Large	_	ADJ	_	Degree=Pos	_	_	_	_
2	amounts	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	viral	_	ADJ	_	Degree=Pos	_	_	_	_
5	RNA	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	particles	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	synthesized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	infections	_	NOUN	_	Number=Plur	_	_	_	_
12	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	using	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	tat	_	NOUN	_	Number=Sing	_	_	_	_
16	mutants	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
5	propagation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	LTR	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	tat	_	NOUN	_	Number=Sing	_	_	_	_
12	mutants	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	some	_	DET	_	_	_	_	_	_
17	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
23	transformed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	other	_	ADJ	_	Degree=Pos	_	_	_	_
26	viruses	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	despite	_	ADP	_	_	_	_	_	_
4	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
5	essential	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	SCONJ	_	_	_	_	_	_
8	releasing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	elongation	_	NOUN	_	Number=Sing	_	_	_	_
11	block	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	Tat	_	PROPN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	otherwise	_	ADV	_	_	_	_	_	_
17	absolutely	_	ADV	_	_	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	full	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	length	_	NOUN	_	Number=Sing	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	assembly	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	virus	_	NOUN	_	Number=Sing	_	_	_	_
31	particles	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Direct	_	ADJ	_	Degree=Pos	_	_	_	_
2	sequencing	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	viral	_	ADJ	_	Degree=Pos	_	_	_	_
6	genomes	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	reinfection	_	NOUN	_	Number=Sing	_	_	_	_
9	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
10	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	no	_	DET	_	_	_	_	_	_
12	evidence	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	wild	_	ADJ	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	type	_	NOUN	_	Number=Sing	_	_	_	_
17	reversion	_	NOUN	_	Number=Sing	_	_	_	_
18	even	_	ADV	_	_	_	_	_	_
19	after	_	ADP	_	_	_	_	_	_
20	prolonged	_	VERB	_	Degree=Pos	_	_	_	_
21	infection	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	Tat	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	virus	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	implications	_	NOUN	_	Number=Plur	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	vivo	_	PROPN	_	Number=Sing	_	_	_	_
6	HIV	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	replication	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	potential	_	ADJ	_	Degree=Pos	_	_	_	_
12	application	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
15	system	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	study	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
21	Tat	_	NOUN	_	Number=Sing	_	_	_	_
22	function	_	NOUN	_	Number=Sing	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300195	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	prointerleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	DNA	_	PROPN	_	Number=Sing	_	_	_	_
9	sequences	_	NOUN	_	Number=Plur	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	distal	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	start	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	tissue	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	induction	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	DNA	_	PROPN	_	Number=Sing	_	_	_	_
9	sequences	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	interactions	_	NOUN	_	Number=Plur	_	_	_	_
14	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	prointerleukin	_	NOUN	_	Number=Sing	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	beta	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	proIL	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	beta	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	independent	_	ADJ	_	Degree=Pos	_	_	_	_
7	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	LPS	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
13	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	between	_	ADP	_	_	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	3757	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	-	_	SYM	_	_	_	_	_	_
21	2729	_	NUM	_	NumType=Card	_	_	_	_
22	bp	_	NOUN	_	Number=Sing	_	_	_	_
23	upstream	_	NOUN	_	Number=Sing	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	start	_	NOUN	_	Number=Sing	_	_	_	_
28	site	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	cap	_	NOUN	_	Number=Sing	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	consisted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	at	_	ADV	_	_	_	_	_	_
36	least	_	ADV	_	Degree=Sup	_	_	_	_
37	six	_	NUM	_	NumType=Card	_	_	_	_
38	discrete	_	NOUN	_	Degree=Pos	_	_	_	_
39	subregions	_	NOUN	_	Number=Plur	_	_	_	_
40	which	_	PRON	_	PronType=Rel	_	_	_	_
41	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
42	essential	_	ADJ	_	Degree=Pos	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
46	induction	_	NOUN	_	Number=Sing	_	_	_	_
47	by	_	ADP	_	_	_	_	_	_
48	LPS	_	NOUN	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	transfected	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
51	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
8	myristate	_	NOUN	_	Number=Sing	_	_	_	_
9	acetate	_	NOUN	_	Number=Sing	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	base	_	NOUN	_	Number=Sing	_	_	_	_
4	substitution	_	NOUN	_	Number=Sing	_	_	_	_
5	mutations	_	NOUN	_	Number=Plur	_	_	_	_
6	along	_	ADP	_	_	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	DNA	_	PROPN	_	Number=Sing	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	studies	_	NOUN	_	Number=Plur	_	_	_	_
11	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
15	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	minimum	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	three	_	NUM	_	NumType=Card	_	_	_	_
20	functional	_	ADJ	_	Degree=Pos	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	sequences	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	two	_	NUM	_	NumType=Card	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	which	_	PRON	_	PronType=Int	_	_	_	_
28	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	important	_	ADJ	_	Degree=Pos	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	induction	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	essential	_	ADJ	_	Degree=Pos	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	bound	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	similar	_	ADJ	_	Degree=Pos	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	identical	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	members	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
20	family	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	both	_	CCONJ	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	LPS	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	specific	_	ADJ	_	Degree=Pos	_	_	_	_
35	induction	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	IL	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	6	_	NUM	_	NumType=Card	_	_	_	_
41	gene	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	i.e.	_	X	_	_	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	NF	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	IL6	_	PROPN	_	Number=Sing	_	_	_	_
49	proteins	_	NOUN	_	Number=Plur	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	ligated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	proIL	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	beta	_	NOUN	_	Number=Sing	_	_	_	_
9	cap	_	NOUN	_	Number=Sing	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	between	_	ADP	_	_	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	131	_	NUM	_	NumType=Card	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_
21	12	_	NUM	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	both	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	proIL	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	beta	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	simian	_	ADJ	_	Degree=Pos	_	_	_	_
33	virus	_	NOUN	_	Number=Sing	_	_	_	_
34	40	_	NUM	_	NumType=Card	_	_	_	_
35	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
36	elements	_	NOUN	_	Number=Plur	_	_	_	_
37	functioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	more	_	ADV	_	_	_	_	_	_
39	efficiently	_	ADV	_	_	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
42	than	_	ADP	_	_	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	which	_	PRON	_	PronType=Rel	_	_	_	_
48	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
49	not	_	PART	_	_	_	_	_	_
50	normally	_	ADV	_	_	_	_	_	_
51	competent	_	ADJ	_	Degree=Pos	_	_	_	_
52	for	_	ADP	_	_	_	_	_	_
53	IL	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	1	_	NUM	_	NumType=Card	_	_	_	_
56	beta	_	NOUN	_	Number=Sing	_	_	_	_
57	expression	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	ligated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	murine	_	NOUN	_	Number=Sing	_	_	_	_
6	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	however	_	ADV	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	proIL	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	beta	_	NOUN	_	Number=Sing	_	_	_	_
16	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
21	myristate	_	NOUN	_	Number=Sing	_	_	_	_
22	acetate	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	existence	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	proIL	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	beta	_	NOUN	_	Number=Sing	_	_	_	_
37	promoter	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
40	requirement	_	NOUN	_	Number=Sing	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	tissue	_	NOUN	_	Number=Sing	_	_	_	_
43	specificity	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	00300197	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interaction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	Tax	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	implications	_	NOUN	_	Number=Plur	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
4	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
15	etiologically	_	ADV	_	_	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	development	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	adult	_	NOUN	_	Number=Sing	_	_	_	_
23	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
24	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	ATL	_	PROPN	_	_	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	as	_	ADV	_	_	_	_	_	_
29	well	_	ADV	_	Degree=Pos	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	degenerative	_	ADJ	_	Degree=Pos	_	_	_	_
32	neurologic	_	ADJ	_	Degree=Pos	_	_	_	_
33	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
34	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	tropical	_	ADJ	_	Degree=Pos	_	_	_	_
36	spastic	_	ADJ	_	Degree=Pos	_	_	_	_
37	paraparesis	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	TSP	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	potent	_	NOUN	_	Degree=Pos	_	_	_	_
7	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	Tax	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	play	_	VERB	_	VerbForm=Inf	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	important	_	ADJ	_	Degree=Pos	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	process	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
23	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Even	_	ADV	_	_	_	_	_	_
2	though	_	SCONJ	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	which	_	DET	_	PronType=Rel	_	_	_	_
7	Tax	_	NOUN	_	Number=Sing	_	_	_	_
8	induces	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	transformation	_	NOUN	_	Number=Sing	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	still	_	ADV	_	_	_	_	_	_
12	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
15	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	likely	_	ADJ	_	Degree=Pos	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	ability	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	Tax	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	many	_	ADJ	_	Degree=Pos	_	_	_	_
28	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
29	genes	_	NOUN	_	Number=Plur	_	_	_	_
30	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	important	_	ADJ	_	Degree=Pos	_	_	_	_
33	part	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
36	process	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
5	directly	_	ADV	_	_	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	DNA	_	PROPN	_	Number=Sing	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	rather	_	ADV	_	_	_	_	_	_
10	deregulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	family	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	host	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	Tax	_	NOUN	_	Number=Sing	_	_	_	_
13	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	Rel	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	post	_	ADJ	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	transcriptionally	_	ADV	_	_	_	_	_	_
8	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	assembly	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
15	family	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	kappa	_	VERB	_	Number=Sing	_	_	_	_
22	B	_	PROPN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	serve	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	sequester	_	VERB	_	VerbForm=Inf	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	Rel	_	NOUN	_	Number=Sing	_	_	_	_
34	complexes	_	NOUN	_	Number=Plur	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	kappa	_	VERB	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	polyubiquitinated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	degraded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	proteolytic	_	ADJ	_	Number=Sing	_	_	_	_
3	event	_	NOUN	_	Number=Sing	_	_	_	_
4	liberates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	permitting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
13	translocation	_	NOUN	_	Number=Sing	_	_	_	_
14	into	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
17	where	_	ADV	_	PronType=Rel	_	_	_	_
18	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
19	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	cognate	_	NOUN	_	Degree=Pos	_	_	_	_
23	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
24	elements	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Similarly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	p105	_	NOUN	_	Number=Sing	_	_	_	_
5	precursor	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	p50	_	PROPN	_	Number=Sing	_	_	_	_
13	subunit	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	post-translationally	_	ADV	_	_	_	_	_	_
17	processed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	Tax	_	NOUN	_	Number=Sing	_	_	_	_
6	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	findings	_	NOUN	_	Number=Plur	_	_	_	_
16	presented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	literature	_	NOUN	_	Number=Sing	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	often	_	ADV	_	_	_	_	_	_
22	controversial	_	ADJ	_	Degree=Pos	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	physical	_	ADJ	_	Degree=Pos	_	_	_	_
5	interaction	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	Tax	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	HsN3	_	NOUN	_	Number=Sing	_	_	_	_
11	subunit	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	raises	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	intriguing	_	ADJ	_	VerbForm=Ger	_	_	_	_
5	possibility	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	DET	_	_	_	_	_	_
7	physical	_	ADJ	_	Degree=Pos	_	_	_	_
8	association	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	HsN3	_	PROPN	_	Number=Sing	_	_	_	_
12	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
13	subunit	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	Tax	_	NOUN	_	Number=Sing	_	_	_	_
19	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	independent	_	ADJ	_	Degree=Pos	_	_	_	_
23	interaction	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	Tax	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	either	_	CCONJ	_	_	_	_	_	_
28	p100	_	NOUN	_	Number=Sing	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	p65	_	NUM	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
33	kappa	_	VERB	_	Number=Sing	_	_	_	_
34	B	_	PROPN	_	Number=Sing	_	_	_	_
35	alpha	_	PROPN	_	Number=Sing	_	_	_	_
36	targets	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
38	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappa	_	NOUN	_	Number=Sing	_	_	_	_
42	B	_	NOUN	_	Number=Sing	_	_	_	_
43	/	_	PUNCT	_	_	_	_	_	_
44	Rel	_	NOUN	_	Number=Sing	_	_	_	_
45	complexes	_	NOUN	_	Number=Plur	_	_	_	_
46	to	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
49	for	_	ADP	_	_	_	_	_	_
50	processing	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001103	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Angiotensin	_	PROPN	_	Number=Sing	_	_	_	_
2	II	_	PROPN	_	Number=Sing	_	_	_	_
3	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	renin	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	angiotensin	_	NOUN	_	Number=Sing	_	_	_	_
5	system	_	NOUN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	common	_	ADJ	_	Degree=Pos	_	_	_	_
3	feature	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	all	_	DET	_	_	_	_	_	_
6	stages	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	vessel	_	NOUN	_	Number=Sing	_	_	_	_
14	wall	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	participates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	most	_	ADV	_	_	_	_	_	_
16	signaling	_	ADJ	_	Degree=Pos	_	_	_	_
17	pathways	_	NOUN	_	Number=Plur	_	_	_	_
18	involved	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	therefore	_	ADV	_	_	_	_	_	_
4	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	angiotensin	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	ANG	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	II	_	NUM	_	NumType=Card	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	major	_	ADJ	_	Degree=Pos	_	_	_	_
24	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
25	component	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	atheroma	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
32	mobility	_	NOUN	_	Number=Sing	_	_	_	_
33	shift	_	NOUN	_	Number=Sing	_	_	_	_
34	assay	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	ANG	_	CCONJ	_	_	_	_	_	_
2	II	_	NUM	_	NumType=Card	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	like	_	ADP	_	_	_	_	_	_
5	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
21	blood	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	Ficoll	_	PROPN	_	Number=Sing	_	_	_	_
24	density	_	NOUN	_	Number=Sing	_	_	_	_
25	gradient	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	ANG	_	NOUN	_	_	_	_	_	_
3	II	_	NUM	_	NumType=Card	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	angiotensin	_	PROPN	_	Number=Sing	_	_	_	_
10	AT1	_	PROPN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
13	losartan	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Specificity	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	ANG	_	PROPN	_	Number=Sing	_	_	_	_
4	II	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	ascertained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	supershift	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	competition	_	NOUN	_	Number=Sing	_	_	_	_
17	experiments	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	ANG	_	PROPN	_	_	_	_	_	_
4	II	_	NUM	_	NumType=Card	_	_	_	_
5	stimulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	same	_	ADJ	_	Degree=Pos	_	_	_	_
21	preparation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	ability	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	vasoactive	_	ADJ	_	Degree=Pos	_	_	_	_
11	peptide	_	NOUN	_	Number=Sing	_	_	_	_
12	ANG	_	NOUN	_	Number=Sing	_	_	_	_
13	II	_	NUM	_	NumType=Card	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	pathways	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1999	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001108	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	X	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	rays	_	NOUN	_	Number=Plur	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	secretion	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	s	_	X	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	enhance	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	s	_	X	_	_	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	various	_	ADJ	_	Degree=Pos	_	_	_	_
25	non-irradiated	_	ADJ	_	Degree=Pos	_	_	_	_
26	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	lines	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Various	_	ADJ	_	Degree=Pos	_	_	_	_
2	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	stress	_	NOUN	_	Number=Sing	_	_	_	_
4	agents	_	NOUN	_	Number=Plur	_	_	_	_
5	like	_	ADP	_	_	_	_	_	_
6	ionizing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	radiation	_	NOUN	_	Number=Sing	_	_	_	_
8	exposure	_	NOUN	_	Number=Sing	_	_	_	_
9	could	_	AUX	_	VerbForm=Fin	_	_	_	_
10	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	type	_	NOUN	_	Number=Sing	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	replication	_	NOUN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	reporter	_	NOUN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	s	_	X	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	released	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	X	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	ray	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	colonic	_	ADJ	_	Number=Sing	_	_	_	_
18	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	line	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	HT29	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	might	_	AUX	_	VerbForm=Fin	_	_	_	_
25	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	long	_	ADJ	_	Degree=Pos	_	_	_	_
28	terminal	_	NOUN	_	Number=Sing	_	_	_	_
29	repeat	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	LTR	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	HIV	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	non-irradiated	_	ADJ	_	Degree=Pos	_	_	_	_
39	HT29	_	ADJ	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	report	_	NOUN	_	Number=Sing	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	various	_	ADJ	_	Degree=Pos	_	_	_	_
10	transiently	_	NOUN	_	_	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	stably	_	ADV	_	_	_	_	_	_
13	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	lines	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	X	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	ray	_	NOUN	_	Number=Sing	_	_	_	_
20	irradiation	_	NOUN	_	Number=Sing	_	_	_	_
21	up	_	ADP	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	HIV	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	LTR	_	NOUN	_	Number=Sing	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	through	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
32	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
33	elements	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	s	_	X	_	_	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	processed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	acts	_	VERB	_	Number=Plur	_	_	_	_
13	upon	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	variety	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	types	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	addition	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	non-irradiated	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	either	_	CCONJ	_	_	_	_	_	_
29	X	_	ADJ	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	ray	_	ADJ	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	conditioned	_	ADJ	_	Degree=Pos	_	_	_	_
38	medium	_	NOUN	_	Number=Sing	_	_	_	_
39	taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	from	_	ADP	_	_	_	_	_	_
41	irradiated	_	ADJ	_	Degree=Pos	_	_	_	_
42	cultures	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	X	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	ray	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	LTR	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	transiently	_	ADJ	_	_	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	stably	_	ADV	_	_	_	_	_	_
17	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	potent	_	ADJ	_	Degree=Pos	_	_	_	_
25	antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
26	drug	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	pyrrolidine	_	NOUN	_	Number=Sing	_	_	_	_
29	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	another	_	DET	_	_	_	_	_	_
33	drug	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
38	role	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	trapping	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	growth	_	NOUN	_	Number=Sing	_	_	_	_
44	factors	_	NOUN	_	Number=Plur	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	suramin	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	importance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	observations	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	pathophysiology	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	patients	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	related	_	ADJ	_	Degree=Pos	_	_	_	_
15	cancers	_	NOUN	_	Number=Plur	_	_	_	_
16	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	radiotherapy	_	NOUN	_	Number=Sing	_	_	_	_
19	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	established	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001111	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Novel	_	NOUN	_	Number=Sing	_	_	_	_
2	therapies	_	NOUN	_	Number=Plur	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	bowel	_	NOUN	_	Number=Sing	_	_	_	_
6	disease	_	NOUN	_	Number=Sing	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	Looking	_	VERB	_	VerbForm=Ger	_	_	_	_
2	back	_	ADV	_	_	_	_	_	_
3	at	_	ADP	_	_	_	_	_	_
4	successes	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	failures	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	newer	_	ADJ	_	Degree=Cmp	_	_	_	_
9	approaches	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	SCONJ	_	_	_	_	_	_
11	treating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	IBD	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	tempting	_	ADJ	_	Degree=Pos	_	_	_	_
17	--	_	PUNCT	_	_	_	_	_	_
18	although	_	SCONJ	_	_	_	_	_	_
19	still	_	ADV	_	_	_	_	_	_
20	difficult	_	ADJ	_	Degree=Pos	_	_	_	_
21	--	_	PUNCT	_	_	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	draw	_	VERB	_	VerbForm=Inf	_	_	_	_
24	conclusions	_	NOUN	_	Number=Plur	_	_	_	_
25	about	_	ADP	_	_	_	_	_	_
26	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	therapy	_	NOUN	_	Number=Sing	_	_	_	_
4	proves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	effective	_	ADJ	_	Degree=Pos	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	clinicians	_	NOUN	_	Number=Plur	_	_	_	_
9	truly	_	ADV	_	_	_	_	_	_
10	know	_	VERB	_	VerbForm=Inf	_	_	_	_
11	how	_	ADV	_	PronType=Int	_	_	_	_
12	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
13	works	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	?	_	PUNCT	_	_	_	_	_	_

1	Even	_	ADV	_	_	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	therapy	_	NOUN	_	Number=Sing	_	_	_	_
5	as	_	ADV	_	_	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	anti-TNF	_	ADJ	_	Degree=Pos	_	_	_	_
9	antibody	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	clear	_	ADJ	_	Degree=Pos	_	_	_	_
15	if	_	SCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	benefit	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	attributable	_	ADJ	_	Degree=Pos	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	simple	_	ADJ	_	Degree=Pos	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	clearance	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	TNF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	binding	_	VERB	_	VerbForm=Inf	_	_	_	_
32	on	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	surface	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
38	deletion	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	drug	_	NOUN	_	Number=Sing	_	_	_	_
4	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	less	_	ADV	_	Degree=Cmp	_	_	_	_
8	effective	_	ADJ	_	Degree=Pos	_	_	_	_
9	than	_	ADP	_	_	_	_	_	_
10	preclinical	_	ADJ	_	Degree=Pos	_	_	_	_
11	models	_	NOUN	_	Number=Plur	_	_	_	_
12	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	failures	_	VERB	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	effectiveness	_	NOUN	_	Number=Sing	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	delivery	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	dosing	_	NOUN	_	Number=Sing	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	differentiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	?	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	disappointing	_	ADJ	_	Degree=Pos	_	_	_	_
3	results	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
6	trials	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	--	_	PUNCT	_	_	_	_	_	_
12	so	_	ADV	_	_	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	odds	_	NOUN	_	Number=Plur	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	prediction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	benefit	_	NOUN	_	Number=Sing	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	animal	_	NOUN	_	Number=Sing	_	_	_	_
22	models	_	NOUN	_	Number=Plur	_	_	_	_
23	--	_	PUNCT	_	_	_	_	_	_
24	bring	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
25	into	_	ADP	_	_	_	_	_	_
26	question	_	NOUN	_	Number=Sing	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	validity	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
31	models	_	NOUN	_	Number=Plur	_	_	_	_
32	as	_	ADV	_	_	_	_	_	_
33	well	_	ADV	_	Degree=Pos	_	_	_	_
34	as	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	soundness	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	design	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
42	trials	_	NOUN	_	Number=Plur	_	_	_	_
43	on	_	ADP	_	_	_	_	_	_
44	which	_	DET	_	PronType=Rel	_	_	_	_
45	efficacy	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	IL	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	10	_	NUM	_	NumType=Card	_	_	_	_
50	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
51	judged	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	variability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	response	_	NOUN	_	Number=Sing	_	_	_	_
5	even	_	ADV	_	_	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	most	_	ADV	_	_	_	_	_	_
9	narrowly	_	ADV	_	_	_	_	_	_
10	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	agents	_	NOUN	_	Number=Plur	_	_	_	_
12	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	diseases	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	far	_	ADV	_	Degree=Pos	_	_	_	_
18	more	_	ADV	_	_	_	_	_	_
19	heterogeneous	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	humans	_	NOUN	_	Number=Plur	_	_	_	_
22	than	_	ADP	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	murine	_	NOUN	_	Number=Sing	_	_	_	_
26	counterparts	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Clinicians	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	only	_	ADV	_	_	_	_	_	_
4	just	_	ADV	_	_	_	_	_	_
5	beginning	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	recognize	_	VERB	_	VerbForm=Inf	_	_	_	_
8	subclinical	_	ADJ	_	Degree=Pos	_	_	_	_
9	markers	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	soon	_	ADV	_	Degree=Pos	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	possible	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	predict	_	VERB	_	VerbForm=Inf	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	basis	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
27	composition	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	moment	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	however	_	ADV	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	field	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	pharmacogenetics	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Challenges	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	SCONJ	_	_	_	_	_	_
3	developing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	new	_	ADJ	_	Degree=Pos	_	_	_	_
5	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
6	strategies	_	NOUN	_	Number=Plur	_	_	_	_
7	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	ADV	_	_	_	_	_	_
9	only	_	ADV	_	_	_	_	_	_
10	identifying	_	VERB	_	VerbForm=Ger	_	_	_	_
11	novel	_	NOUN	_	Number=Sing	_	_	_	_
12	agents	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	improving	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	definitions	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
21	endpoints	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	defining	_	VERB	_	VerbForm=Ger	_	_	_	_
24	efficacy	_	NOUN	_	Number=Sing	_	_	_	_
25	at	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	biologic	_	ADJ	_	Number=Sing	_	_	_	_
28	level	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Only	_	ADV	_	_	_	_	_	_
2	through	_	ADP	_	_	_	_	_	_
3	considered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	evaluation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
7	evidence	_	NOUN	_	Number=Sing	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	clinicians	_	NOUN	_	Number=Plur	_	_	_	_
10	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
11	which	_	DET	_	PronType=Int	_	_	_	_
12	therapies	_	NOUN	_	Number=Plur	_	_	_	_
13	should	_	AUX	_	VerbForm=Fin	_	_	_	_
14	remain	_	VERB	_	VerbForm=Inf	_	_	_	_
15	novelties	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Int	_	_	_	_
18	should	_	AUX	_	VerbForm=Fin	_	_	_	_
19	become	_	VERB	_	VerbForm=Inf	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	accepted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	part	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	armamentarium	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001112	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	TRAMP	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	sequence	_	NOUN	_	Number=Sing	_	_	_	_
11	homology	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	tumor	_	VERB	_	VerbForm=Inf	_	_	_	_
14	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	Fas	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	Apo	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1/CD95	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	member	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	tumor	_	NOUN	_	Number=Sing	_	_	_	_
7	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	TNF	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	family	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	TRAMP	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
20	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	structural	_	ADJ	_	Degree=Pos	_	_	_	_
3	organization	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	393	_	NUM	_	NumType=Card	_	_	_	_
7	amino	_	NOUN	_	Number=Sing	_	_	_	_
8	acid	_	VERB	_	Number=Sing	_	_	_	_
9	long	_	ADJ	_	Degree=Pos	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	TRAMP	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	most	_	ADV	_	_	_	_	_	_
14	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	TRAMP	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	abundantly	_	ADV	_	_	_	_	_	_
4	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	domain	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	four	_	NUM	_	NumType=Card	_	_	_	_
8	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	rich	_	ADJ	_	Degree=Pos	_	_	_	_
11	domains	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	death	_	NOUN	_	Number=Sing	_	_	_	_
20	domain	_	NOUN	_	Number=Sing	_	_	_	_
21	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	signal	_	VERB	_	VerbForm=Inf	_	_	_	_
24	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TRAMP	_	NOUN	_	Number=Sing	_	_	_	_
4	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	major	_	ADJ	_	Degree=Pos	_	_	_	_
8	responses	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	TRAMP	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	death	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	ICE	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	like	_	ADP	_	Degree=Pos	_	_	_	_
15	proteases	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	TRAMP	_	PROPN	_	Number=Sing	_	_	_	_
5	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	appear	_	VERB	_	VerbForm=Inf	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	any	_	DET	_	_	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	ligands	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	TNF	_	PROPN	_	Number=Sing	_	_	_	_
22	family	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001115	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Selective	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	functional	_	ADJ	_	Degree=Pos	_	_	_	_
5	significance	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	p38alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
7	selectively	_	ADV	_	_	_	_	_	_
8	initiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	transduction	_	NOUN	_	Number=Sing	_	_	_	_
12	via	_	ADP	_	_	_	_	_	_
13	sequential	_	ADJ	_	Degree=Pos	_	_	_	_
14	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	kinases	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Lipopolysaccharide	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	LPS	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	result	_	VERB	_	VerbForm=Inf	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	p38	_	NOUN	_	Number=Sing	_	_	_	_
17	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	kinase	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	MAPk	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	;	_	PUNCT	_	_	_	_	_	_
26	however	_	ADV	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
30	activator	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	s	_	X	_	_	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	p38	_	NOUN	_	Number=Sing	_	_	_	_
36	MAPk	_	NOUN	_	Number=Sing	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	consequences	_	NOUN	_	Number=Plur	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	p38	_	NOUN	_	Number=Sing	_	_	_	_
44	MAPk	_	NOUN	_	Number=Sing	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
47	largely	_	ADV	_	_	_	_	_	_
48	undefined	_	ADJ	_	Degree=Pos	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	MAPk	_	PROPN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	MKK	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	p38	_	NOUN	_	Number=Sing	_	_	_	_
12	MAPk	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	LPS	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	p38	_	PROPN	_	Number=Sing	_	_	_	_
20	MAPk	_	NOUN	_	Number=Sing	_	_	_	_
21	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	part	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
29	pathway	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	functional	_	ADJ	_	Degree=Pos	_	_	_	_
34	responses	_	NOUN	_	Number=Plur	_	_	_	_
35	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	p38	_	NOUN	_	Number=Sing	_	_	_	_
38	MAPk	_	NOUN	_	Number=Sing	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	MKK3	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	MKK4	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	MKK6	_	PROPN	_	Number=Sing	_	_	_	_
8	all	_	DET	_	_	_	_	_	_
9	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	p38	_	NUM	_	Number=Sing	_	_	_	_
11	MAPk	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	experimental	_	ADJ	_	Degree=Pos	_	_	_	_
14	models	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	only	_	ADV	_	_	_	_	_	_
17	MKK3	_	PROPN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
23	p38	_	NOUN	_	Number=Sing	_	_	_	_
24	MAPk	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	LPS	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Of	_	ADP	_	_	_	_	_	_
2	p38	_	NOUN	_	Number=Sing	_	_	_	_
3	MAPk	_	PROPN	_	Number=Sing	_	_	_	_
4	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
5	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	only	_	ADV	_	_	_	_	_	_
8	p38alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	p38delta	_	NOUN	_	Number=Sing	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	NOUN	_	Number=Sing	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	selectively	_	ADV	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	p38alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	Specific	_	ADJ	_	Degree=Pos	_	_	_	_
2	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p38alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	MAPk	_	PROPN	_	Number=Sing	_	_	_	_
6	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	LPS	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	tumor	_	NOUN	_	Number=Sing	_	_	_	_
28	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	TNF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	alpha	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	p38alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	MAPk	_	PROPN	_	Number=Sing	_	_	_	_
5	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	transient	_	ADJ	_	Degree=Pos	_	_	_	_
9	decrease	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
15	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
18	loss	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	TNF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	pathway	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	LPS	_	PROPN	_	Number=Sing	_	_	_	_
9	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	neutrophils	_	NOUN	_	Degree=Pos	_	_	_	_
12	results	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	MKK3	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	turn	_	NOUN	_	Number=Sing	_	_	_	_
21	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	p38alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	MAPk	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	ultimately	_	ADV	_	_	_	_	_	_
26	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
27	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	TNF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	alpha	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	regulation	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	TNF	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	alpha	_	NOUN	_	Number=Sing	_	_	_	_
48	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001117	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Thrombin	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	thrombin	_	VERB	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	agonist	_	NOUN	_	Degree=Pos	_	_	_	_
6	peptide	_	NOUN	_	Number=Sing	_	_	_	_
7	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	early	_	ADJ	_	Degree=Pos	_	_	_	_
9	events	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	synergize	_	VERB	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	TCR	_	NOUN	_	Number=Sing	_	_	_	_
18	cross	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	linking	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	CD69	_	PROPN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	production	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Thrombin	_	VERB	_	Number=Sing	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	line	_	NOUN	_	Number=Sing	_	_	_	_
9	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
10	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	transient	_	ADJ	_	Degree=Pos	_	_	_	_
13	increase	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	[	_	PUNCT	_	_	_	_	_	_
16	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
17	+	_	SYM	_	_	_	_	_	_
18	]	_	PUNCT	_	_	_	_	_	_
19	i	_	X	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_
21	Proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	effect	_	NOUN	_	Number=Sing	_	_	_	_
31	since	_	SCONJ	_	_	_	_	_	_
32	diisopropyl	_	ADJ	_	Number=Sing	_	_	_	_
33	fluorophosphate	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
36	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	to	_	PART	_	_	_	_	_	_
38	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
39	[	_	PUNCT	_	_	_	_	_	_
40	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
41	+	_	SYM	_	_	_	_	_	_
42	]	_	PUNCT	_	_	_	_	_	_
43	i	_	X	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_
45	Furthermore	_	ADV	_	_	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	hirudin	_	NOUN	_	Number=Sing	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	anti-thrombin	_	ADJ	_	Degree=Pos	_	_	_	_
50	III	_	PROPN	_	Number=Sing	_	_	_	_
51	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
56	[	_	PUNCT	_	_	_	_	_	_
57	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
58	+	_	SYM	_	_	_	_	_	_
59	]	_	PUNCT	_	_	_	_	_	_
60	i	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
61	rise	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
62	in	_	ADP	_	_	_	_	_	_
63	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
64	T	_	PROPN	_	Number=Sing	_	_	_	_
65	cells	_	NOUN	_	Number=Plur	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
3	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	agonist	_	NOUN	_	Number=Sing	_	_	_	_
6	peptide	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	TRP	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	7	_	NUM	_	NumType=Card	_	_	_	_
12	residues	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	SFLLRNP	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	as	_	ADV	_	_	_	_	_	_
21	effective	_	ADJ	_	Degree=Pos	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	[	_	PUNCT	_	_	_	_	_	_
26	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
27	+]	_	PUNCT	_	_	_	_	_	_
28	i	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
29	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	both	_	DET	_	_	_	_	_	_
33	agonists	_	NOUN	_	Number=Plur	_	_	_	_
34	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
36	+	_	SYM	_	_	_	_	_	_
37	release	_	NOUN	_	Number=Sing	_	_	_	_
38	exclusively	_	ADV	_	_	_	_	_	_
39	from	_	ADP	_	_	_	_	_	_
40	internal	_	ADJ	_	Degree=Pos	_	_	_	_
41	stores	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Thrombin	_	PROPN	_	Number=Sing	_	_	_	_
2	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	tyrosine	_	ADJ	_	Number=Sing	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	several	_	ADJ	_	Degree=Pos	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
10	mass	_	ADJ	_	Degree=Pos	_	_	_	_
11	40	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	42	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	70	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	120	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	130	_	NUM	_	NumType=Card	_	_	_	_
21	kDa	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	good	_	ADJ	_	Degree=Pos	_	_	_	_
5	correlation	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
11	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	latter	_	ADJ	_	Degree=Pos	_	_	_	_
15	three	_	NUM	_	NumType=Card	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Thrombin	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	TRP	_	PROPN	_	Number=Sing	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	translocation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	C	_	NOUN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	plasma	_	NOUN	_	Number=Sing	_	_	_	_
17	membrane	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	likely	_	ADJ	_	Degree=Pos	_	_	_	_
4	consequence	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	events	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
10	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kB	_	PROPN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
6	origin	_	NOUN	_	Number=Sing	_	_	_	_
7	including	_	VERB	_	VerbForm=Ger	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	line	_	NOUN	_	Number=Sing	_	_	_	_
13	HPB.	_	PROPN	_	Number=Sing	_	_	_	_
14	ALL	_	DET	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	erythroleukemic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	line	_	NOUN	_	Number=Sing	_	_	_	_
20	K562	_	NOUN	_	Number=Sing	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	whereas	_	SCONJ	_	_	_	_	_	_
27	others	_	NOUN	_	Number=Plur	_	_	_	_
28	such	_	ADJ	_	Degree=Pos	_	_	_	_
29	as	_	ADP	_	_	_	_	_	_
30	THP1	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	line	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	BL2	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	Burkitt	_	NOUN	_	Number=Sing	_	_	_	_
42	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
43	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
44	refractory	_	ADJ	_	Degree=Pos	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
47	or	_	CCONJ	_	_	_	_	_	_
48	TRP	_	NOUN	_	Number=Sing	_	_	_	_
49	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	thrombin	_	ADJ	_	Degree=Pos	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	different	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	types	_	NOUN	_	Number=Plur	_	_	_	_
12	paralleled	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	DET	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	combination	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
16	12	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	myristate	_	NOUN	_	Number=Sing	_	_	_	_
19	13	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	acetate	_	NOUN	_	Number=Sing	_	_	_	_
22	led	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
26	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
36	loss	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	thrombin	_	ADJ	_	Number=Sing	_	_	_	_
40	response	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	TRP	_	NOUN	_	Number=Sing	_	_	_	_
9	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	CD69	_	PROPN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	production	_	NOUN	_	Number=Sing	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	T	_	PROPN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	cross	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	both	_	CCONJ	_	_	_	_	_	_
26	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
31	blood	_	NOUN	_	Number=Sing	_	_	_	_
32	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	highlight	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	potential	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulator	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001118	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Oct	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Oct	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	member	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	POU	_	PROPN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	Pit	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	Oct	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	Unc	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	family	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	only	_	ADV	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	B	_	ADJ	_	Degree=Pos	_	_	_	_
30	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	neuronal	_	ADJ	_	Degree=Pos	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	but	_	CCONJ	_	_	_	_	_	_
36	not	_	PART	_	_	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	other	_	ADJ	_	Degree=Pos	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	types	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	primary	_	ADJ	_	Degree=Pos	_	_	_	_
3	RNA	_	PROPN	_	Number=Sing	_	_	_	_
4	transcript	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	subject	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
12	splicing	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	yield	_	VERB	_	VerbForm=Inf	_	_	_	_
15	different	_	ADJ	_	Degree=Pos	_	_	_	_
16	variants	_	NOUN	_	Number=Plur	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	can	_	AUX	_	VerbForm=Fin	_	_	_	_
19	either	_	CCONJ	_	_	_	_	_	_
20	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	repress	_	VERB	_	VerbForm=Inf	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	forms	_	NOUN	_	Number=Plur	_	_	_	_
3	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	B	_	NOUN	_	Degree=Pos	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	predominantly	_	ADV	_	_	_	_	_	_
10	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	effect	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	whereas	_	SCONJ	_	_	_	_	_	_
16	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
17	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	neuronal	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	predominantly	_	ADV	_	_	_	_	_	_
24	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
25	effect	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	can	_	AUX	_	VerbForm=Fin	_	_	_	_
28	repress	_	VERB	_	VerbForm=Inf	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	both	_	CCONJ	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	herpes	_	NOUN	_	Number=Sing	_	_	_	_
35	simplex	_	ADJ	_	VerbForm=Ger	_	_	_	_
36	virus	_	NOUN	_	Number=Sing	_	_	_	_
37	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	early	_	ADJ	_	Degree=Pos	_	_	_	_
40	genes	_	NOUN	_	Number=Plur	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
44	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
45	hydroxylase	_	NOUN	_	Degree=Pos	_	_	_	_
46	gene	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	Oct	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	important	_	ADJ	_	Degree=Pos	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	B	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	neuronal	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	as	_	ADV	_	_	_	_	_	_
24	well	_	ADV	_	Degree=Pos	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	control	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	viral	_	ADJ	_	Degree=Pos	_	_	_	_
31	latency	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001119	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interactions	_	NOUN	_	Number=Plur	_	_	_	_
2	between	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	class	_	NOUN	_	Number=Sing	_	_	_	_
5	II	_	NUM	_	NumType=Card	_	_	_	_
6	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	CREB	_	PROPN	_	Number=Sing	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	increase	_	NOUN	_	Number=Sing	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	major	_	ADJ	_	Degree=Pos	_	_	_	_
15	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
16	complex	_	NOUN	_	Degree=Pos	_	_	_	_
17	class	_	NOUN	_	Number=Sing	_	_	_	_
18	II	_	NUM	_	Number=Sing	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Class	_	NOUN	_	Number=Sing	_	_	_	_
2	II	_	NUM	_	NumType=Card	_	_	_	_
3	major	_	ADJ	_	Degree=Pos	_	_	_	_
4	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	class	_	NOUN	_	Number=Sing	_	_	_	_
7	II	_	NUM	_	NumType=Card	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	gamma	_	NOUN	_	Number=Sing	_	_	_	_
21	interferon	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
24	fashion	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	master	_	NOUN	_	Number=Sing	_	_	_	_
3	switch	_	NOUN	_	Number=Sing	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	class	_	NOUN	_	Number=Sing	_	_	_	_
13	II	_	NUM	_	NumType=Card	_	_	_	_
14	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	one	_	NUM	_	NumType=Card	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	functions	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
14	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	recruit	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	CREB	_	PROPN	_	Number=Sing	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	CBP	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	class	_	NOUN	_	Number=Sing	_	_	_	_
26	II	_	NUM	_	NumType=Card	_	_	_	_
27	promoters	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Not	_	ADV	_	_	_	_	_	_
2	only	_	ADV	_	_	_	_	_	_
3	functional	_	ADJ	_	Degree=Pos	_	_	_	_
4	but	_	CCONJ	_	_	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	interactions	_	NOUN	_	Number=Plur	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	CBP	_	PROPN	_	Number=Sing	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
5	negative	_	ADJ	_	Degree=Pos	_	_	_	_
6	form	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	CBP	_	NOUN	_	Number=Sing	_	_	_	_
9	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	class	_	NOUN	_	Number=Sing	_	_	_	_
14	II	_	NUM	_	NumType=Card	_	_	_	_
15	promoters	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	levels	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	class	_	NOUN	_	Number=Sing	_	_	_	_
20	II	_	NUM	_	NumType=Card	_	_	_	_
21	determinants	_	NOUN	_	Number=Plur	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	surface	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	class	_	NOUN	_	Number=Sing	_	_	_	_
7	II	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
13	hormone	_	NOUN	_	Number=Sing	_	_	_	_
14	could	_	AUX	_	VerbForm=Fin	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	attributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	squelching	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	CBP	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
25	receptor	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	CBP	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	histone	_	NOUN	_	Number=Sing	_	_	_	_
8	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	important	_	ADJ	_	Degree=Pos	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	class	_	NOUN	_	Number=Sing	_	_	_	_
19	II	_	PROPN	_	Number=Sing	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001123	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
3	zinc	_	NOUN	_	Number=Sing	_	_	_	_
4	finger	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	MZF	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	CD34	_	PROPN	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	vitro	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	MZF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	C2H2	_	NOUN	_	Number=Sing	_	_	_	_
7	zinc	_	NOUN	_	Number=Sing	_	_	_	_
8	finger	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	putative	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulator	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	MZF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	13	_	NUM	_	NumType=Card	_	_	_	_
8	C2H2	_	NOUN	_	Number=Sing	_	_	_	_
9	zinc	_	NOUN	_	Number=Sing	_	_	_	_
10	fingers	_	NOUN	_	Number=Plur	_	_	_	_
11	arranged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	bipartite	_	ADJ	_	Degree=Pos	_	_	_	_
14	DNA	_	PROPN	_	Number=Sing	_	_	_	_
15	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
16	domains	_	NOUN	_	Number=Plur	_	_	_	_
17	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	zinc	_	NOUN	_	Number=Sing	_	_	_	_
19	fingers	_	NOUN	_	Number=Plur	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	carboxy	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	terminus	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	5	_	NUM	_	NumType=Card	_	_	_	_
31	through	_	ADP	_	_	_	_	_	_
32	13	_	NUM	_	NumType=Card	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	consensus	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	recognized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	two	_	NUM	_	NumType=Card	_	_	_	_
13	DNA	_	PROPN	_	Number=Sing	_	_	_	_
14	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	domains	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	assess	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	function	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	MZF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	full	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	length	_	NOUN	_	Number=Sing	_	_	_	_
16	MZF	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	coding	_	NOUN	_	Number=Sing	_	_	_	_
20	region	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	fused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	DNA	_	PROPN	_	Number=Sing	_	_	_	_
26	binding	_	VERB	_	Number=Sing	_	_	_	_
27	domain	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	yeast	_	NOUN	_	Number=Sing	_	_	_	_
31	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
32	GAL4	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	vector	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	cotransfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	chloramphenicol	_	NOUN	_	Number=Sing	_	_	_	_
9	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
10	transferase	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	CAT	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	reporter	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	GAL4	_	PROPN	_	Number=Sing	_	_	_	_
24	DNA	_	NOUN	_	Number=Sing	_	_	_	_
25	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
26	sites	_	NOUN	_	Number=Plur	_	_	_	_
27	into	_	ADP	_	_	_	_	_	_
28	NIH	_	PROPN	_	Number=Sing	_	_	_	_
29	3T3	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	293	_	NUM	_	NumType=Card	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	K562	_	NUM	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	lines	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	MZF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	represses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	CAT	_	NOUN	_	Number=Sing	_	_	_	_
6	reporter	_	NOUN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	via	_	ADP	_	_	_	_	_	_
10	GAL4	_	PROPN	_	Number=Sing	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	nonhematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	lines	_	NOUN	_	Number=Plur	_	_	_	_
18	NIH	_	PROPN	_	Number=Sing	_	_	_	_
19	3T3	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	293	_	NUM	_	NumType=Card	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	MZF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	CAT	_	NOUN	_	Number=Sing	_	_	_	_
9	reporter	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	lines	_	NOUN	_	Number=Plur	_	_	_	_
17	K562	_	NUM	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	MZF	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	present	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	promoters	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	several	_	ADJ	_	Degree=Pos	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	during	_	ADP	_	_	_	_	_	_
17	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	including	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	CD34	_	PROPN	_	Number=Sing	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	MZF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	physiologically	_	ADV	_	_	_	_	_	_
9	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	nonhematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Recombinant	_	ADJ	_	Number=Sing	_	_	_	_
2	MZF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	specifically	_	ADV	_	_	_	_	_	_
7	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	consensus	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	CD34	_	PROPN	_	Number=Sing	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	mobility	_	NOUN	_	Number=Sing	_	_	_	_
19	shift	_	NOUN	_	Number=Sing	_	_	_	_
20	assays	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	MZF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	vectors	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	cotransfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
11	reporter	_	NOUN	_	Number=Sing	_	_	_	_
12	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	CD34	_	PROPN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	into	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	nonhematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	lines	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	domain	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	MZF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	represses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	reporter	_	NOUN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	nonhematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	activates	_	VERB	_	Number=Plur	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	lines	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CD34	_	PROPN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	presence	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	intact	_	VERB	_	VerbForm=Ger	_	_	_	_
16	MZF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	sites	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	type	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	CD34	_	PROPN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	MZF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	presence	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	tissue	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	specific	_	ADJ	_	Degree=Pos	_	_	_	_
22	regulators	_	NOUN	_	Number=Plur	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	adapters	_	NOUN	_	Number=Plur	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	differential	_	ADJ	_	Degree=Pos	_	_	_	_
27	MZF	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	modifications	_	NOUN	_	Number=Plur	_	_	_	_
31	that	_	PRON	_	PronType=Rel	_	_	_	_
32	determine	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	MZF	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
37	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
38	function	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001126	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
3	histone	_	NOUN	_	Number=Sing	_	_	_	_
4	deacetylase	_	NOUN	_	Number=Sing	_	_	_	_
5	related	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	yeast	_	NOUN	_	Number=Sing	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulator	_	NOUN	_	Number=Sing	_	_	_	_
11	Rpd3p	_	NOUN	_	Number=Sing	_	_	_	_
12	[	_	PUNCT	_	_	_	_	_	_
13	see	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
14	comments	_	NOUN	_	Number=Plur	_	_	_	_
15	]	_	PUNCT	_	_	_	_	_	_

1	Trapoxin	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	microbially	_	ADV	_	_	_	_	_	_
5	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	cyclotetrapeptide	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	histone	_	NOUN	_	Number=Sing	_	_	_	_
10	deacetylation	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	vivo	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	arrest	_	VERB	_	VerbForm=Inf	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	cycle	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	trapoxin	_	NOUN	_	Degree=Pos	_	_	_	_
3	affinity	_	NOUN	_	Number=Sing	_	_	_	_
4	matrix	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	isolate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	copurified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	histone	_	NOUN	_	Number=Sing	_	_	_	_
16	deacetylase	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	proteins	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	peptide	_	NOUN	_	Number=Sing	_	_	_	_
7	microsequencing	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	complementary	_	ADJ	_	Degree=Pos	_	_	_	_
12	DNA	_	NOUN	_	Number=Sing	_	_	_	_
13	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	histone	_	NOUN	_	Number=Sing	_	_	_	_
16	deacetylase	_	NOUN	_	Number=Sing	_	_	_	_
17	catalytic	_	ADJ	_	Number=Sing	_	_	_	_
18	subunit	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	HD1	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
28	T	_	PROPN	_	Number=Sing	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	library	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	predicted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	very	_	ADV	_	_	_	_	_	_
7	similar	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	yeast	_	NOUN	_	Number=Sing	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	regulator	_	NOUN	_	Number=Sing	_	_	_	_
13	Rpd3p	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
16	results	_	NOUN	_	Number=Plur	_	_	_	_
17	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	role	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	histone	_	NOUN	_	Number=Sing	_	_	_	_
22	deacetylase	_	NOUN	_	Number=Sing	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	key	_	ADJ	_	Degree=Pos	_	_	_	_
26	regulator	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	eukaryotic	_	ADJ	_	Degree=Pos	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001130	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	BCL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	6	_	NUM	_	NumType=Card	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	during	_	ADP	_	_	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Translocations	_	NOUN	_	Number=Plur	_	_	_	_
2	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	BCL	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	common	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	diffuse	_	NOUN	_	Degree=Pos	_	_	_	_
13	large	_	ADJ	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	subtype	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	non-Hodgkin	_	NOUN	_	Number=Sing	_	_	_	_
18	's	_	PART	_	_	_	_	_	_
19	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Invariably	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	BCL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	coding	_	NOUN	_	Number=Sing	_	_	_	_
8	region	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	intact	_	ADJ	_	Degree=Pos	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	5	_	NUM	_	NumType=Card	_	_	_	_
15	'	_	PUNCT	_	_	_	_	_	_
16	untranslated	_	ADJ	_	Degree=Pos	_	_	_	_
17	region	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	replaced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	sequences	_	NOUN	_	Number=Plur	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	translocation	_	NOUN	_	Number=Sing	_	_	_	_
25	partner	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	BCL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	during	_	ADP	_	_	_	_	_	_
15	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
16	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Resting	_	VERB	_	VerbForm=Ger	_	_	_	_
2	B	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	high	_	ADJ	_	Degree=Pos	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	BCL	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	6	_	NUM	_	NumType=Card	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	mouse	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	anti-IgM	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	IgD	_	NOUN	_	Degree=Pos	_	_	_	_
10	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
13	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
16	12	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	myristate	_	NOUN	_	Number=Sing	_	_	_	_
19	13	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	acetate	_	ADJ	_	Number=Sing	_	_	_	_
22	plus	_	CCONJ	_	_	_	_	_	_
23	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	CD40	_	PROPN	_	Number=Sing	_	_	_	_
27	ligand	_	NOUN	_	Number=Sing	_	_	_	_
28	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	five	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	fold	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	35	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
38	decrease	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	BCL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	6	_	NUM	_	NumType=Card	_	_	_	_
43	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
44	levels	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	downregulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	BCL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	Staphylococcus	_	PROPN	_	Number=Sing	_	_	_	_
17	aureus	_	NOUN	_	Number=Sing	_	_	_	_
18	plus	_	CCONJ	_	_	_	_	_	_
19	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	anti-IgM	_	ADJ	_	Degree=Pos	_	_	_	_
24	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	BCL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	6	_	NUM	_	NumType=Card	_	_	_	_
4	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	began	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	decrease	_	VERB	_	VerbForm=Inf	_	_	_	_
9	8	_	NUM	_	NumType=Card	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	16	_	NUM	_	NumType=Card	_	_	_	_
12	hours	_	NOUN	_	Number=Plur	_	_	_	_
13	after	_	ADP	_	_	_	_	_	_
14	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	before	_	ADP	_	_	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	entered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	S	_	NOUN	_	_	_	_	_	_
20	phase	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	B	_	ADJ	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	vitro	_	NOUN	_	Number=Sing	_	_	_	_
9	invariably	_	ADV	_	_	_	_	_	_
10	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	BCL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	MRNA	_	PROPN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	B	_	ADJ	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	germinal	_	ADJ	_	Degree=Pos	_	_	_	_
23	centers	_	NOUN	_	Number=Plur	_	_	_	_
24	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	BCL	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	6	_	NUM	_	NumType=Card	_	_	_	_
28	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
29	at	_	ADP	_	_	_	_	_	_
30	levels	_	NOUN	_	Number=Plur	_	_	_	_
31	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	levels	_	NOUN	_	Number=Plur	_	_	_	_
35	in	_	SCONJ	_	_	_	_	_	_
36	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Despite	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	similar	_	ADJ	_	Degree=Pos	_	_	_	_
4	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	BCL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	6	_	NUM	_	NumType=Card	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	threefold	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	34	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
18	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	germinal	_	ADJ	_	Degree=Pos	_	_	_	_
21	center	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	ADJ	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	than	_	ADP	_	_	_	_	_	_
25	in	_	SCONJ	_	_	_	_	_	_
26	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
27	B	_	ADJ	_	Degree=Pos	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	BCL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	6	_	NUM	_	NumType=Card	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	levels	_	NOUN	_	Number=Plur	_	_	_	_
37	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	translational	_	ADJ	_	Degree=Pos	_	_	_	_
41	or	_	CCONJ	_	_	_	_	_	_
42	posttranslational	_	ADJ	_	Degree=Pos	_	_	_	_
43	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	germinal	_	ADJ	_	Degree=Pos	_	_	_	_
7	center	_	NOUN	_	Number=Sing	_	_	_	_
8	reaction	_	NOUN	_	Number=Sing	_	_	_	_
9	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	unique	_	ADJ	_	Degree=Pos	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	signals	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	B	_	ADJ	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	allow	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	continued	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	high	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	level	_	NOUN	_	Number=Sing	_	_	_	_
24	BCL	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	6	_	NUM	_	NumType=Card	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001134	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Involvement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	SAF	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	like	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	serum	_	NOUN	_	Number=Sing	_	_	_	_
14	amyloid	_	NOUN	_	Number=Sing	_	_	_	_
15	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Serum	_	PROPN	_	Number=Sing	_	_	_	_
2	amyloid	_	PROPN	_	Number=Sing	_	_	_	_
3	A	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	SAA	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
9	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
12	because	_	ADP	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	ability	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	remodel	_	VERB	_	VerbForm=Inf	_	_	_	_
18	high	_	ADJ	_	Degree=Pos	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	density	_	NOUN	_	Number=Sing	_	_	_	_
21	lipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	depletion	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	apolipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
27	A1	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
30	ability	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
33	cholesterol	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
37	presence	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	atherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
41	plaques	_	NOUN	_	Number=Plur	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	coronary	_	ADJ	_	Number=Sing	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	carotid	_	ADJ	_	Number=Sing	_	_	_	_
46	arteries	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	SAA	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	THP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	critical	_	ADJ	_	Degree=Pos	_	_	_	_
26	role	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	development	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	atherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
32	fatty	_	NOUN	_	Number=Sing	_	_	_	_
33	streak	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	plaque	_	NOUN	_	Number=Sing	_	_	_	_
36	formation	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	others	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	SAA	_	PROPN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	LPS	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	promoter	_	NOUN	_	Number=Sing	_	_	_	_
3	function	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	SAA	_	PROPN	_	Number=Sing	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	sequence	_	NOUN	_	Number=Sing	_	_	_	_
13	between	_	ADP	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	280	_	NUM	_	NumType=Card	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	226	_	NUM	_	NumType=Card	_	_	_	_
19	can	_	AUX	_	VerbForm=Fin	_	_	_	_
20	confer	_	VERB	_	VerbForm=Inf	_	_	_	_
21	LPS	_	NOUN	_	Number=Sing	_	_	_	_
22	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assay	_	NOUN	_	Number=Sing	_	_	_	_
6	detected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	DNA	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	LPS	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	UV	_	PROPN	_	Number=Sing	_	_	_	_
10	cross	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	linking	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	Southwestern	_	ADJ	_	Degree=Pos	_	_	_	_
15	blot	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	antibody	_	ADJ	_	Number=Sing	_	_	_	_
19	ablation	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	supershift	_	NOUN	_	Number=Sing	_	_	_	_
22	assays	_	NOUN	_	Number=Plur	_	_	_	_
23	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	similar	_	ADJ	_	Degree=Pos	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	recently	_	ADV	_	_	_	_	_	_
31	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	SAF	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	LPS	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	mediated	_	VERB	_	Degree=Pos	_	_	_	_
8	SAA	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	primarily	_	ADV	_	_	_	_	_	_
18	due	_	ADP	_	_	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	induction	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	SAF	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001143	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	Tax	_	VERB	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	Rel	_	NOUN	_	Number=Sing	_	_	_	_
16	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	degradation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	kappa	_	VERB	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	alpha	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	RelA	_	PROPN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	p65	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	induction	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	c-rel	_	NOUN	_	Degree=Pos	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	tax	_	NOUN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	product	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
8	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
9	virus	_	NOUN	_	Number=Sing	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	potent	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	activator	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	both	_	DET	_	_	_	_	_	_
24	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	viral	_	ADJ	_	Degree=Pos	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	array	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
34	genes	_	NOUN	_	Number=Plur	_	_	_	_
35	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
38	growth	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	acts	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	indirectly	_	ADV	_	_	_	_	_	_
4	by	_	SCONJ	_	_	_	_	_	_
5	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	modifying	_	VERB	_	VerbForm=Ger	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	action	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	various	_	ADJ	_	Degree=Pos	_	_	_	_
12	host	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	including	_	VERB	_	VerbForm=Ger	_	_	_	_
17	members	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	Rel	_	NOUN	_	Number=Sing	_	_	_	_
26	family	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	binding	_	VERB	_	Number=Sing	_	_	_	_
31	proteins	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	SCONJ	_	_	_	_	_	_
2	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	many	_	ADJ	_	Degree=Pos	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	Rel	_	NOUN	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	sequestered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	various	_	ADJ	_	Degree=Pos	_	_	_	_
23	ankyrin	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	rich	_	ADJ	_	Degree=Pos	_	_	_	_
26	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
27	proteins	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	including	_	VERB	_	VerbForm=Ger	_	_	_	_
30	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
31	kappa	_	VERB	_	Number=Sing	_	_	_	_
32	B	_	PROPN	_	Number=Sing	_	_	_	_
33	alpha	_	PROPN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	Tax	_	VERB	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	biologically	_	ADV	_	_	_	_	_	_
14	active	_	ADJ	_	Degree=Pos	_	_	_	_
15	NF	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
21	complexes	_	NOUN	_	Number=Plur	_	_	_	_
22	;	_	PUNCT	_	_	_	_	_	_
23	however	_	ADV	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
27	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	s	_	X	_	_	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	response	_	NOUN	_	Number=Sing	_	_	_	_
34	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	poorly	_	ADV	_	_	_	_	_	_
36	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	Tax	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	I-infected	_	ADJ	_	Degree=Pos	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	Tax	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
37	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
38	degradation	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
41	kappa	_	VERB	_	Number=Sing	_	_	_	_
42	B	_	PROPN	_	Number=Sing	_	_	_	_
43	alpha	_	PROPN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	prior	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	vitro	_	NOUN	_	Number=Sing	_	_	_	_
7	studies	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	at	_	ADV	_	_	_	_	_	_
10	least	_	ADV	_	Degree=Sup	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	fraction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	phosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
16	form	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	kappa	_	PROPN	_	Number=Sing	_	_	_	_
20	B	_	PROPN	_	Number=Sing	_	_	_	_
21	alpha	_	PROPN	_	Number=Sing	_	_	_	_
22	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	physically	_	ADV	_	_	_	_	_	_
24	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	complex	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	vivo	_	NOUN	_	Number=Sing	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	subject	_	ADJ	_	Degree=Pos	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
39	degradation	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	thereby	_	ADV	_	_	_	_	_	_
42	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
45	translocation	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	active	_	ADJ	_	Degree=Pos	_	_	_	_
49	NF	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	kappa	_	NOUN	_	Number=Sing	_	_	_	_
52	B	_	NOUN	_	Number=Sing	_	_	_	_
53	complex	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Tax	_	NOUN	_	Number=Sing	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	RelA	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	p65	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	subunit	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	which	_	PRON	_	PronType=Rel	_	_	_	_
27	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	c-rel	_	NOUN	_	Degree=Pos	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	through	_	ADP	_	_	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	intrinsic	_	ADJ	_	Degree=Pos	_	_	_	_
36	kappa	_	NOUN	_	Number=Sing	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
39	element	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	normal	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
7	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
11	acts	_	NOUN	_	Number=Plur	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
14	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	own	_	ADJ	_	Degree=Pos	_	_	_	_
16	continued	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	presence	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	loop	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	003001145	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Nitric	_	ADJ	_	Number=Sing	_	_	_	_
2	oxide	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	guanine	_	NOUN	_	Number=Sing	_	_	_	_
6	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
7	exchange	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	protooncogene	_	NOUN	_	Number=Sing	_	_	_	_
3	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	monomeric	_	ADJ	_	Degree=Pos	_	_	_	_
7	G	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	family	_	NOUN	_	Number=Sing	_	_	_	_
10	member	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	critical	_	ADJ	_	Degree=Pos	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	SCONJ	_	_	_	_	_	_
17	converting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
19	signals	_	NOUN	_	Number=Plur	_	_	_	_
20	into	_	ADP	_	_	_	_	_	_
21	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
23	events	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	nitric	_	PROPN	_	Number=Sing	_	_	_	_
7	oxide	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	NO	_	INTJ	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	as	_	SCONJ	_	_	_	_	_	_
18	evidenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	increase	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	GTP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	bound	_	ADJ	_	Degree=Pos	_	_	_	_
26	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	using	_	VERB	_	VerbForm=Ger	_	_	_	_
5	pure	_	ADJ	_	Degree=Pos	_	_	_	_
6	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
7	p21ras	_	NOUN	_	Number=Plur	_	_	_	_
8	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	direct	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	reversible	_	ADJ	_	Degree=Pos	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Circular	_	ADJ	_	Degree=Pos	_	_	_	_
2	dichroism	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	reveals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	NO	_	DET	_	_	_	_	_	_
7	induces	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	profound	_	ADJ	_	Degree=Pos	_	_	_	_
10	conformational	_	ADJ	_	Degree=Pos	_	_	_	_
11	change	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	association	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	GDP	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	GTP	_	NOUN	_	Number=Sing	_	_	_	_
20	exchange	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	due	_	ADP	_	_	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	S	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	nitrosylation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	critical	_	ADJ	_	Degree=Pos	_	_	_	_
14	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
15	residue	_	NOUN	_	Number=Sing	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	guanine	_	ADJ	_	Number=Sing	_	_	_	_
19	nucleotide	_	ADJ	_	Number=Sing	_	_	_	_
20	exchange	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	essential	_	ADJ	_	Degree=Pos	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	NO	_	DET	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
14	signaling	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	such	_	ADJ	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
27	NO	_	DET	_	_	_	_	_	_
28	can	_	AUX	_	VerbForm=Fin	_	_	_	_
29	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
30	p21ras	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	same	_	ADJ	_	Degree=Pos	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	p21ras	_	NOUN	_	Number=Plur	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	target	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	same	_	ADJ	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	p21ras	_	NOUN	_	Number=Plur	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	target	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NO	_	DET	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	NO	_	DET	_	_	_	_	_	_
17	activates	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	action	_	NOUN	_	Number=Sing	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	mimics	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	guanine	_	ADJ	_	Degree=Pos	_	_	_	_
27	nucleotide	_	NOUN	_	Number=Sing	_	_	_	_
28	exchange	_	NOUN	_	Number=Sing	_	_	_	_
29	factors	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001147	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	spatial	_	ADJ	_	Degree=Pos	_	_	_	_
3	distribution	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
7	genes	_	NOUN	_	Number=Plur	_	_	_	_
8	within	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	evidence	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	topography	_	NOUN	_	Number=Sing	_	_	_	_
16	independent	_	ADJ	_	Degree=Pos	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	type	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	three	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	dimensional	_	ADJ	_	Degree=Pos	_	_	_	_
5	positioning	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	Ig	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	within	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	using	_	VERB	_	VerbForm=Ger	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	situ	_	NOUN	_	Number=Sing	_	_	_	_
23	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	confocal	_	ADJ	_	Degree=Pos	_	_	_	_
26	microscopy	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	visualization	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	light	_	NOUN	_	Degree=Pos	_	_	_	_
7	chain	_	NOUN	_	Number=Sing	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	B	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	three	_	NUM	_	NumType=Card	_	_	_	_
18	Ig	_	NOUN	_	Number=Sing	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	differentially	_	ADV	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	nonrandomly	_	ADV	_	_	_	_	_	_
24	distributed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	different	_	ADJ	_	Degree=Pos	_	_	_	_
27	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
28	subvolumes	_	NOUN	_	Number=Plur	_	_	_	_
29	:	_	PUNCT	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	be	_	AUX	_	VerbForm=Inf	_	_	_	_
37	preferentially	_	ADV	_	_	_	_	_	_
38	confined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	outer	_	ADJ	_	Degree=Pos	_	_	_	_
42	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
43	volume	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	whereas	_	SCONJ	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	gamma	_	NOUN	_	Number=Sing	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	lambda	_	NOUN	_	Number=Sing	_	_	_	_
50	genes	_	NOUN	_	Number=Plur	_	_	_	_
51	consistently	_	ADV	_	_	_	_	_	_
52	occupied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
53	more	_	ADJ	_	Degree=Cmp	_	_	_	_
54	central	_	ADJ	_	Degree=Pos	_	_	_	_
55	positions	_	NOUN	_	Number=Plur	_	_	_	_
56	within	_	ADP	_	_	_	_	_	_
57	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
58	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
59	,	_	PUNCT	_	_	_	_	_	_
60	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
61	lambda	_	NOUN	_	Number=Sing	_	_	_	_
62	genes	_	NOUN	_	Number=Plur	_	_	_	_
63	being	_	AUX	_	VerbForm=Ger	_	_	_	_
64	more	_	ADJ	_	Degree=Cmp	_	_	_	_
65	interior	_	ADJ	_	Degree=Pos	_	_	_	_
66	when	_	ADV	_	PronType=Int	_	_	_	_
67	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
68	with	_	ADP	_	_	_	_	_	_
69	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
70	gamma	_	NOUN	_	Number=Sing	_	_	_	_
71	genes	_	NOUN	_	Number=Plur	_	_	_	_
72	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	further	_	ADV	_	Degree=Pos	_	_	_	_
4	show	_	VERB	_	Number=Sing	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	overall	_	ADJ	_	Degree=Pos	_	_	_	_
8	topographical	_	ADJ	_	Degree=Pos	_	_	_	_
9	distributions	_	NOUN	_	Number=Plur	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	independent	_	ADJ	_	Degree=Pos	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	conserved	_	VERB	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	different	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	types	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	subtle	_	ADJ	_	Degree=Pos	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	movements	_	NOUN	_	Number=Plur	_	_	_	_
5	within	_	ADP	_	_	_	_	_	_
6	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	defined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	topographical	_	ADJ	_	Degree=Pos	_	_	_	_
9	regions	_	NOUN	_	Number=Plur	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	excluded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	study	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	results	_	NOUN	_	Number=Plur	_	_	_	_
20	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	tissue	_	NOUN	_	Degree=Pos	_	_	_	_
23	specificity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	drastic	_	ADJ	_	Degree=Pos	_	_	_	_
32	changes	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
36	topography	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	rather	_	ADV	_	_	_	_	_	_
39	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
40	that	_	SCONJ	_	_	_	_	_	_
41	gene	_	NOUN	_	Number=Sing	_	_	_	_
42	organization	_	NOUN	_	Number=Sing	_	_	_	_
43	within	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
46	may	_	AUX	_	VerbForm=Fin	_	_	_	_
47	be	_	AUX	_	VerbForm=Inf	_	_	_	_
48	primarily	_	ADV	_	_	_	_	_	_
49	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
50	on	_	ADP	_	_	_	_	_	_
51	structural	_	ADJ	_	Degree=Pos	_	_	_	_
52	constraints	_	NOUN	_	Number=Plur	_	_	_	_
53	imposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
54	on	_	ADP	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	respective	_	ADJ	_	Degree=Pos	_	_	_	_
57	chromosomes	_	NOUN	_	Number=Plur	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001153	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	V3	_	NOUN	_	Number=Sing	_	_	_	_
2	loop	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	suppresses	_	NOUN	_	Number=Plur	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	growth	_	NOUN	_	Number=Sing	_	_	_	_
17	[	_	PUNCT	_	_	_	_	_	_
18	published	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	erratum	_	NOUN	_	Number=Sing	_	_	_	_
20	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
23	Res	_	NOUN	_	Number=Sing	_	_	_	_
24	Hum	_	PROPN	_	Number=Sing	_	_	_	_
25	Retroviruses	_	PROPN	_	Number=Plur	_	_	_	_
26	1997	_	NUM	_	NumType=Card	_	_	_	_
27	May	_	PROPN	_	Number=Sing	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	;	_	PUNCT	_	_	_	_	_	_
30	13	_	NUM	_	NumType=Card	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	7):633	_	NUM	_	NumType=Card	_	_	_	_
33	]	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	three	_	NUM	_	NumType=Card	_	_	_	_
7	linear	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	loop	_	NOUN	_	Number=Sing	_	_	_	_
11	peptides	_	NOUN	_	Number=Plur	_	_	_	_
12	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	V3	_	PROPN	_	Number=Sing	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	III	_	PROPN	_	NumType=Card	_	_	_	_
22	BH10	_	PROPN	_	Number=Sing	_	_	_	_
23	clone	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	SF2	_	PROPN	_	Number=Sing	_	_	_	_
27	strain	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
31	virus	_	NOUN	_	Number=Sing	_	_	_	_
32	type	_	NOUN	_	Number=Sing	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	on	_	ADP	_	_	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	T	_	NOUN	_	Number=Sing	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	V3	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	BH10	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	consists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	42	_	NUM	_	NumType=Card	_	_	_	_
9	amino	_	NOUN	_	Degree=Pos	_	_	_	_
10	acids	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	loop	_	NOUN	_	Number=Sing	_	_	_	_
15	structure	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	all	_	DET	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	[	_	PUNCT	_	_	_	_	_	_
33	Kit225	_	NUM	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	ED	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	40515	_	NUM	_	NumType=Card	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	+	_	SYM	_	_	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	KT	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	3	_	NUM	_	NumType=Card	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	7	_	NUM	_	NumType=Card	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	day	_	NOUN	_	Number=Sing	_	_	_	_
49	PHA	_	NOUN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	blasts	_	NOUN	_	Number=Plur	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	and	_	CCONJ	_	_	_	_	_	_
54	fresh	_	ADJ	_	Degree=Pos	_	_	_	_
55	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
56	blood	_	NOUN	_	Number=Sing	_	_	_	_
57	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
58	cells	_	NOUN	_	Number=Plur	_	_	_	_
59	]	_	PUNCT	_	_	_	_	_	_
60	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
61	,	_	PUNCT	_	_	_	_	_	_
62	whereas	_	SCONJ	_	_	_	_	_	_
63	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
64	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
65	not	_	PART	_	_	_	_	_	_
66	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
67	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
68	cell	_	NOUN	_	Number=Sing	_	_	_	_
69	growth	_	NOUN	_	Number=Sing	_	_	_	_
70	of	_	ADP	_	_	_	_	_	_
71	IL	_	PROPN	_	Number=Sing	_	_	_	_
72	-	_	PUNCT	_	_	_	_	_	_
73	2	_	NUM	_	NumType=Card	_	_	_	_
74	-	_	PUNCT	_	_	_	_	_	_
75	independent	_	ADJ	_	Degree=Pos	_	_	_	_
76	cell	_	NOUN	_	Number=Sing	_	_	_	_
77	lines	_	NOUN	_	Number=Plur	_	_	_	_
78	(	_	PUNCT	_	_	_	_	_	_
79	Hut102	_	NOUN	_	NumType=Card	_	_	_	_
80	,	_	PUNCT	_	_	_	_	_	_
81	Molt	_	NOUN	_	Number=Sing	_	_	_	_
82	-	_	PUNCT	_	_	_	_	_	_
83	4	_	NUM	_	NumType=Card	_	_	_	_
84	,	_	PUNCT	_	_	_	_	_	_
85	and	_	CCONJ	_	_	_	_	_	_
86	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
87	)	_	PUNCT	_	_	_	_	_	_
88	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	suppressive	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	growth	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	CD8	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	positive	_	ADJ	_	Degree=Pos	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	7	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	day	_	NOUN	_	Number=Sing	_	_	_	_
25	PHA	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	blasts	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
30	that	_	SCONJ	_	_	_	_	_	_
31	CD4	_	NOUN	_	Number=Sing	_	_	_	_
32	molecules	_	NOUN	_	Number=Plur	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	suppression	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	anti-V3	_	ADJ	_	Degree=Pos	_	_	_	_
5	loop	_	NOUN	_	Number=Sing	_	_	_	_
6	monoclonal	_	ADJ	_	Number=Sing	_	_	_	_
7	antibody	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	902	_	NUM	_	NumType=Card	_	_	_	_
10	antibody	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	completely	_	ADV	_	_	_	_	_	_
13	abolished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	suppressive	_	ADJ	_	Degree=Pos	_	_	_	_
16	effect	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	V3-BH10	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	V3-BH10	_	PROPN	_	Number=Sing	_	_	_	_
5	generated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	arrest	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Kit225	_	NUM	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	CD8	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	positive	_	ADJ	_	Degree=Pos	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	G1	_	PROPN	_	Number=Sing	_	_	_	_
20	phase	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	presence	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Neither	_	DET	_	_	_	_	_	_
2	chromatin	_	ADJ	_	Degree=Pos	_	_	_	_
3	condensation	_	NOUN	_	Number=Sing	_	_	_	_
4	nor	_	CCONJ	_	_	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	fragmentation	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	Kit225	_	NUM	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	V3-BH10	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	V3	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	BH10	_	PROPN	_	Number=Sing	_	_	_	_
4	neither	_	CCONJ	_	_	_	_	_	_
5	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	radiolabeled	_	VERB	_	Number=Sing	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	receptors	_	NOUN	_	Number=Plur	_	_	_	_
16	nor	_	CCONJ	_	_	_	_	_	_
17	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	tyrosyl	_	ADJ	_	Number=Sing	_	_	_	_
19	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	several	_	ADJ	_	Degree=Pos	_	_	_	_
22	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	p120	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	p98	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	p96	_	NUM	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	p54	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	p38	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	which	_	PRON	_	PronType=Rel	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	immediately	_	ADV	_	_	_	_	_	_
40	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	2	_	NUM	_	NumType=Card	_	_	_	_
45	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	V3-BH10	_	PROPN	_	Number=Sing	_	_	_	_
4	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	c	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	fos	_	NOUN	_	Number=Sing	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	c-myc	_	ADJ	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	junB	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	V3	_	NOUN	_	Number=Sing	_	_	_	_
7	loop	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	gp120	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	surface	_	NOUN	_	Number=Sing	_	_	_	_
14	molecule	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	s	_	X	_	_	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
21	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	signaling	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	suppression	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	T	_	NOUN	_	Number=Sing	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	growth	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001156	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	T	_	NUM	_	NumType=Card	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	negative	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	pleiotropic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
13	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
14	growth	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	types	_	NOUN	_	Number=Plur	_	_	_	_
21	such	_	ADJ	_	Degree=Pos	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	B	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	mast	_	ADJ	_	Degree=Pos	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	elements	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	negative	_	ADJ	_	Degree=Pos	_	_	_	_
8	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	NRE	_	X	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	composed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	sites	_	NOUN	_	Number=Plur	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	mapped	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	5	_	NUM	_	NumType=Card	_	_	_	_
25	'	_	PUNCT	_	_	_	_	_	_
26	flanking	_	VERB	_	Number=Sing	_	_	_	_
27	region	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	4	_	NUM	_	NumType=Card	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	:	_	PUNCT	_	_	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	311CTCCCTTCT	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	303	_	NUM	_	NumType=Card	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	NRE	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	I	_	NUM	_	NumType=Card	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	288CTTTTTGCTT	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	TGC	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	300	_	NUM	_	NumType=Card	_	_	_	_
51	(	_	PUNCT	_	_	_	_	_	_
52	NRE	_	NOUN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	II	_	NUM	_	NumType=Card	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	T	_	NUM	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	Neg	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	Neg	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	NRE	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	NRE	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	II	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	respectively	_	ADV	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	positive	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	element	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	45	_	NUM	_	NumType=Card	_	_	_	_
10	bp	_	NOUN	_	Number=Sing	_	_	_	_
11	downstream	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	NRE	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	PRE	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	completely	_	ADV	_	_	_	_	_	_
9	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	when	_	ADV	_	PronType=Int	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	NRE	_	PROPN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	present	_	ADJ	_	Degree=Pos	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	normally	_	ADV	_	_	_	_	_	_
12	down	_	ADV	_	_	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	NRE	_	NOUN	_	Number=Sing	_	_	_	_
18	via	_	ADP	_	_	_	_	_	_
19	repression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
23	positive	_	ADJ	_	Degree=Pos	_	_	_	_
24	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	element	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	may	_	AUX	_	VerbForm=Fin	_	_	_	_
4	have	_	VERB	_	VerbForm=Inf	_	_	_	_
5	implications	_	NOUN	_	Number=Plur	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	stringent	_	ADJ	_	Degree=Pos	_	_	_	_
9	control	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001157	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	CD28	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	signaling	_	NOUN	_	Number=Sing	_	_	_	_
6	pathway	_	NOUN	_	Number=Sing	_	_	_	_
7	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
16	without	_	ADP	_	_	_	_	_	_
17	TCR	_	NOUN	_	Number=Sing	_	_	_	_
18	engagement	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	SCONJ	_	_	_	_	_	_
3	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	CD28-specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	mAb	_	NOUN	_	Number=Sing	_	_	_	_
11	BW	_	PROPN	_	Number=Sing	_	_	_	_
12	828	_	NUM	_	NumType=Card	_	_	_	_
13	induces	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
17	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
18	without	_	ADP	_	_	_	_	_	_
19	further	_	ADJ	_	Degree=Pos	_	_	_	_
20	requirement	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	TCR	_	NOUN	_	Number=Sing	_	_	_	_
23	coengagement	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	observation	_	NOUN	_	Number=Sing	_	_	_	_
3	prompted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	us	_	PRON	_	Case=Acc|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	postulate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	that	_	DET	_	_	_	_	_	_
8	signal	_	NOUN	_	Number=Sing	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	signal	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	alone	_	ADJ	_	_	_	_	_	_
15	without	_	ADP	_	_	_	_	_	_
16	signal	_	NOUN	_	Number=Sing	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	TCR	_	NOUN	_	Number=Sing	_	_	_	_
20	signal	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	can	_	AUX	_	VerbForm=Fin	_	_	_	_
23	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	test	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	putative	_	ADJ	_	Degree=Pos	_	_	_	_
6	function	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	CD28	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	via	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	particular	_	ADJ	_	Degree=Pos	_	_	_	_
14	signaling	_	NOUN	_	Number=Sing	_	_	_	_
15	pathway	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
18	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	early	_	ADJ	_	Degree=Pos	_	_	_	_
20	signaling	_	VERB	_	Number=Sing	_	_	_	_
21	events	_	NOUN	_	Number=Plur	_	_	_	_
22	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	in	_	SCONJ	_	_	_	_	_	_
24	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
30	mAb	_	NOUN	_	Number=Sing	_	_	_	_
31	BW	_	PROPN	_	Number=Sing	_	_	_	_
32	828	_	NUM	_	NumType=Card	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	signals	_	NOUN	_	Number=Plur	_	_	_	_
35	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	nonstimulating	_	ADJ	_	Degree=Pos	_	_	_	_
39	CD28	_	PROPN	_	Number=Sing	_	_	_	_
40	mAb	_	NOUN	_	Number=Sing	_	_	_	_
41	9.3	_	NUM	_	NumType=Card	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	BW	_	PROPN	_	Number=Sing	_	_	_	_
7	828	_	NUM	_	NumType=Card	_	_	_	_
8	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	increase	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
13	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
14	+	_	SYM	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	kinases	_	NOUN	_	Number=Plur	_	_	_	_
27	p56	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	lck	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	c	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	Raf	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	pathway	_	NOUN	_	Number=Sing	_	_	_	_
3	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	AT	_	ADP	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	proteins	_	VERB	_	Number=Plur	_	_	_	_
22	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	CD28	_	PROPN	_	Number=Sing	_	_	_	_
26	response	_	NOUN	_	Number=Sing	_	_	_	_
27	element	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	hand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	mAb	_	PROPN	_	Number=Sing	_	_	_	_
12	9.3	_	NUM	_	NumType=Card	_	_	_	_
13	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	triggered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	p56	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	lck	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	c-Raf	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	unable	_	ADJ	_	Degree=Pos	_	_	_	_
37	to	_	PART	_	_	_	_	_	_
38	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	binding	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	transcription	_	NOUN	_	Number=Sing	_	_	_	_
43	factors	_	NOUN	_	Number=Plur	_	_	_	_
44	to	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	IL	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	2	_	NUM	_	NumType=Card	_	_	_	_
49	promoter	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	differential	_	ADJ	_	Degree=Pos	_	_	_	_
6	signaling	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	BW	_	PROPN	_	Number=Sing	_	_	_	_
9	828	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	9.3	_	NUM	_	NumType=Card	_	_	_	_
12	in	_	SCONJ	_	_	_	_	_	_
13	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	two	_	NUM	_	NumType=Card	_	_	_	_
19	mAbs	_	NOUN	_	Number=Plur	_	_	_	_
20	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	similar	_	ADJ	_	Degree=Pos	_	_	_	_
23	pattern	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	early	_	ADJ	_	Degree=Pos	_	_	_	_
26	signaling	_	ADJ	_	Number=Sing	_	_	_	_
27	events	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	T	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	p56	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	lck	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	association	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	phosphatidylinositol	_	NOUN	_	Number=Sing	_	_	_	_
45	3	_	NUM	_	NumType=Card	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	kinase	_	NOUN	_	Number=Sing	_	_	_	_
48	with	_	ADP	_	_	_	_	_	_
49	CD28	_	NOUN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
53	that	_	SCONJ	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	signaling	_	NOUN	_	Number=Sing	_	_	_	_
56	capacity	_	NOUN	_	Number=Sing	_	_	_	_
57	of	_	ADP	_	_	_	_	_	_
58	CD28	_	NOUN	_	Number=Sing	_	_	_	_
59	changes	_	NOUN	_	Number=Plur	_	_	_	_
60	with	_	ADP	_	_	_	_	_	_
61	activation	_	NOUN	_	Number=Sing	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	view	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	DET	_	PronType=Rel	_	_	_	_
7	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	CD28	_	PROPN	_	Number=Sing	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
12	some	_	DET	_	_	_	_	_	_
13	effector	_	NOUN	_	Number=Sing	_	_	_	_
14	functions	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	suggest	_	VERB	_	VerbForm=Inf	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	capacity	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	particular	_	ADJ	_	Degree=Pos	_	_	_	_
28	pattern	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	early	_	ADJ	_	Degree=Pos	_	_	_	_
31	signaling	_	NOUN	_	Number=Sing	_	_	_	_
32	events	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001159	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Thapsigargin	_	PROPN	_	Number=Sing	_	_	_	_
2	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	chain	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	peripheral	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	via	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	C	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	independent	_	ADJ	_	Degree=Pos	_	_	_	_
24	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Thapsigargin	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	TG	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Ca	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	+)-	_	PUNCT	_	_	_	_	_	_
13	ATPase	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	depletes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
17	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
18	+	_	CCONJ	_	_	_	_	_	_
19	stores	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	sustained	_	VERB	_	Degree=Pos	_	_	_	_
24	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
25	+	_	SYM	_	_	_	_	_	_
26	influx	_	NOUN	_	Number=Sing	_	_	_	_
27	without	_	SCONJ	_	_	_	_	_	_
28	altering	_	VERB	_	VerbForm=Ger	_	_	_	_
29	phosphatidyl	_	ADJ	_	Number=Sing	_	_	_	_
30	inositol	_	NOUN	_	Number=Sing	_	_	_	_
31	levels	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	TG	_	PROPN	_	Number=Sing	_	_	_	_
2	plus	_	CCONJ	_	_	_	_	_	_
3	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
4	myristate	_	NOUN	_	Number=Sing	_	_	_	_
5	acetate	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	PMA	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	TG	_	PROPN	_	Number=Sing	_	_	_	_
12	alone	_	ADV	_	_	_	_	_	_
13	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	TG	_	PROPN	_	Number=Sing	_	_	_	_
25	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	no	_	DET	_	_	_	_	_	_
27	effect	_	NOUN	_	Number=Sing	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	C	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	PKC	_	PROPN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	TG	_	PROPN	_	Number=Sing	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	increases	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2R	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADV	_	_	_	_	_	_
13	well	_	ADV	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2R	_	PROPN	_	Number=Sing	_	_	_	_
18	alpha	_	PROPN	_	Number=Sing	_	_	_	_
19	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	dose	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
29	manner	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	similar	_	ADJ	_	Degree=Pos	_	_	_	_
3	increase	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2R	_	NOUN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	TG	_	PROPN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	like	_	ADP	_	_	_	_	_	_
4	PMA	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	TG	_	PROPN	_	Number=Sing	_	_	_	_
7	markedly	_	ADV	_	_	_	_	_	_
8	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	TG	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	PMA	_	PROPN	_	Number=Sing	_	_	_	_
6	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
9	action	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2R	_	NOUN	_	Number=Sing	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	TG	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	PMA	_	PROPN	_	Number=Sing	_	_	_	_
22	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2R	_	NUM	_	Number=Sing	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	through	_	ADP	_	_	_	_	_	_
28	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
29	pathways	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	PMA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	but	_	CCONJ	_	_	_	_	_	_
4	not	_	ADV	_	_	_	_	_	_
5	TG	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2R	_	NOUN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	PKC	_	PROPN	_	Number=Sing	_	_	_	_
17	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_

1	H7	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	whereas	_	ADV	_	_	_	_	_	_
4	TG	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	but	_	CCONJ	_	_	_	_	_	_
7	not	_	ADV	_	_	_	_	_	_
8	PMA	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2R	_	NOUN	_	Number=Sing	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	cholera	_	NOUN	_	Number=Sing	_	_	_	_
19	toxin	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	forskolin	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	1,9	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dideoxy	_	NOUN	_	Number=Sing	_	_	_	_
26	forskolin	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	toto	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	TG	_	PROPN	_	Number=Sing	_	_	_	_
9	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2R	_	PROPN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	PKC	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	independent	_	ADJ	_	Degree=Pos	_	_	_	_
23	pathway	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001163	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Functions	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
6	disulfide	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	immunology	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	immunopathology	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Even	_	ADV	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	moderate	_	ADJ	_	Degree=Pos	_	_	_	_
4	increase	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
9	supply	_	NOUN	_	Number=Sing	_	_	_	_
10	elevates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
13	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	GSH	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
19	disulfide	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	GSSG	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	potentiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	immunological	_	ADJ	_	Degree=Pos	_	_	_	_
27	functions	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	vitro	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	low	_	ADJ	_	Degree=Pos	_	_	_	_
3	GSSG	_	NOUN	_	Number=Sing	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	optimally	_	ADV	_	_	_	_	_	_
11	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	immunologically	_	ADV	_	_	_	_	_	_
14	important	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	kappa	_	PROPN	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whereas	_	SCONJ	_	_	_	_	_	_
22	high	_	ADJ	_	Degree=Pos	_	_	_	_
23	GSSG	_	NOUN	_	Number=Sing	_	_	_	_
24	levels	_	NOUN	_	Number=Plur	_	_	_	_
25	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	DNA	_	PROPN	_	Number=Sing	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B.	_	PROPN	_	_	_	_	_	_
34	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	effects	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	GSSG	_	PROPN	_	Number=Sing	_	_	_	_
38	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	antagonized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	thioredoxin	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	TRX	_	NOUN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	activities	_	NOUN	_	Number=Plur	_	_	_	_
7	p56lck	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	p59fyn	_	NOUN	_	Number=Plur	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	intact	_	NOUN	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	hydrogen	_	NOUN	_	Number=Sing	_	_	_	_
17	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	likely	_	ADJ	_	Degree=Pos	_	_	_	_
22	targets	_	NOUN	_	Number=Plur	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	GSSG	_	PROPN	_	Number=Sing	_	_	_	_
25	action	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	redox	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	enzymes	_	NOUN	_	Number=Plur	_	_	_	_
6	trigger	_	VERB	_	VerbForm=Inf	_	_	_	_
7	signal	_	NOUN	_	Number=Sing	_	_	_	_
8	cascades	_	NOUN	_	Number=Plur	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	transduce	_	VERB	_	Number=Sing	_	_	_	_
16	signals	_	NOUN	_	Number=Plur	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	antigen	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	CD4	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	CD8	_	PROPN	_	Number=Sing	_	_	_	_
28	molecules	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	receptor	_	NOUN	_	Number=Sing	_	_	_	_
37	beta-chain	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effector	_	NOUN	_	Number=Sing	_	_	_	_
3	phase	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
6	T	_	NOUN	_	NumType=Card	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	responses	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	functions	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	even	_	ADV	_	_	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	partial	_	ADJ	_	Degree=Pos	_	_	_	_
22	depletion	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
26	GSH	_	NOUN	_	Number=Sing	_	_	_	_
27	pool	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	signal	_	ADJ	_	Number=Sing	_	_	_	_
3	transduction	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	facilitated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	prooxidant	_	ADJ	_	Degree=Pos	_	_	_	_
8	conditions	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	well	_	ADV	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	immunological	_	ADJ	_	Degree=Pos	_	_	_	_
18	consequences	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	GSH	_	PROPN	_	Number=Sing	_	_	_	_
21	depletion	_	NOUN	_	Number=Sing	_	_	_	_
22	ultimately	_	ADV	_	_	_	_	_	_
23	may	_	AUX	_	VerbForm=Fin	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	results	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	accompanying	_	VERB	_	Degree=Pos	_	_	_	_
29	GSSG	_	NOUN	_	Number=Sing	_	_	_	_
30	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	HIV	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	patients	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	SIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	rhesus	_	NOUN	_	Number=Sing	_	_	_	_
11	macaques	_	NOUN	_	Number=Plur	_	_	_	_
12	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	average	_	ADJ	_	Degree=Pos	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	significantly	_	ADV	_	_	_	_	_	_
19	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	plasma	_	NOUN	_	Number=Sing	_	_	_	_
21	cyst	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	e	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	ine	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
28	GSH	_	NOUN	_	Number=Sing	_	_	_	_
29	levels	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
32	also	_	ADV	_	_	_	_	_	_
33	hypothesize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	that	_	SCONJ	_	_	_	_	_	_
35	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
36	may	_	AUX	_	VerbForm=Fin	_	_	_	_
37	be	_	AUX	_	VerbForm=Inf	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	consequence	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	GSSG	_	NOUN	_	Number=Sing	_	_	_	_
43	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
44	as	_	ADV	_	_	_	_	_	_
45	well	_	ADV	_	Degree=Pos	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001170	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	6	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	into	_	ADP	_	_	_	_	_	_
13	IgM	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	secreting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	plasma	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	c	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	fos	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	protooncogene	_	NOUN	_	Number=Sing	_	_	_	_
6	c	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	fos	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	6	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	SKW	_	PROPN	_	Number=Sing	_	_	_	_
4	6.4	_	NUM	_	NumType=Card	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	transient	_	ADJ	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	early	_	ADJ	_	Degree=Pos	_	_	_	_
14	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	c	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	fos	_	ADP	_	_	_	_	_	_
19	sense	_	NOUN	_	Number=Sing	_	_	_	_
20	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	within	_	ADP	_	_	_	_	_	_
5	30	_	NUM	_	NumType=Card	_	_	_	_
6	min	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	returned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	basal	_	ADJ	_	Degree=Pos	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	h	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	antisense	_	ADJ	_	Number=Sing	_	_	_	_
5	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	c	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	fos	_	NOUN	_	Number=Sing	_	_	_	_
10	significantly	_	ADV	_	_	_	_	_	_
11	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	IgM	_	NOUN	_	Number=Sing	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	SKW	_	PROPN	_	Number=Sing	_	_	_	_
20	6.4	_	NUM	_	NumType=Card	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	p	_	NOUN	_	Number=Sing	_	_	_	_
24	less	_	ADJ	_	Degree=Cmp	_	_	_	_
25	than	_	ADP	_	_	_	_	_	_
26	0.001	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	whereas	_	SCONJ	_	_	_	_	_	_
30	control	_	NOUN	_	Number=Sing	_	_	_	_
31	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
32	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	no	_	DET	_	_	_	_	_	_
34	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
35	effect	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	c	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	fos	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	involved	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	6	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	SKW	_	PROPN	_	Number=Sing	_	_	_	_
20	6.4	_	NUM	_	NumType=Card	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	into	_	ADP	_	_	_	_	_	_
23	IgM	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	secreting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001174	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Dopamine	_	NOUN	_	Number=Sing	_	_	_	_
2	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	via	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	immune	_	NOUN	_	Number=Sing	_	_	_	_
20	system	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	produce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	transport	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
12	dopamine	_	NOUN	_	Number=Sing	_	_	_	_
13	present	_	VERB	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	plasma	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	action	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	dopamine	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	immune	_	ADJ	_	Number=Sing	_	_	_	_
18	system	_	NOUN	_	Number=Sing	_	_	_	_
19	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	yet	_	ADV	_	_	_	_	_	_
22	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
23	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	dopamine	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	primary	_	ADJ	_	Degree=Pos	_	_	_	_
22	blood	_	NOUN	_	Number=Sing	_	_	_	_
23	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	replication	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	dopamine	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	correlated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	transient	_	ADJ	_	Degree=Pos	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	dopamine	_	NOUN	_	Number=Sing	_	_	_	_
8	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	through	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	element	_	NOUN	_	Number=Sing	_	_	_	_
16	present	_	VERB	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	long	_	ADJ	_	Degree=Pos	_	_	_	_
20	terminal	_	NOUN	_	Number=Sing	_	_	_	_
21	repeat	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	importance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	SCONJ	_	_	_	_	_	_
11	using	_	VERB	_	VerbForm=Ger	_	_	_	_
12	vectors	_	NOUN	_	Number=Plur	_	_	_	_
13	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	wild	_	ADJ	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	type	_	NOUN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	sites	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	dopamine	_	NOUN	_	Number=Sing	_	_	_	_
12	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
16	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
17	MG132	_	PROPN	_	Number=Sing	_	_	_	_
18	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	dopamine	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	explored	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	dopamine	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	presence	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
13	esters	_	NOUN	_	Number=Plur	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	tumor	_	NOUN	_	Number=Sing	_	_	_	_
16	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha	_	PROPN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	TNF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	combination	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	dopamine	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	TNF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	HIV	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	replication	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	contrast	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	TNF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	dopamine	_	NOUN	_	Degree=Pos	_	_	_	_
11	treatment	_	NOUN	_	Number=Sing	_	_	_	_
12	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	DNA	_	NOUN	_	Number=Sing	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	nor	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	p50	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	p65	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	which	_	PRON	_	PronType=Rel	_	_	_	_
35	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
41	activation	_	NOUN	_	Number=Sing	_	_	_	_
42	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	new	_	ADJ	_	Degree=Pos	_	_	_	_
6	link	_	NOUN	_	Number=Sing	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	dopamine	_	NOUN	_	Number=Sing	_	_	_	_
10	system	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	cytokine	_	VERB	_	Number=Sing	_	_	_	_
13	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
14	pathway	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	via	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	involvement	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	T	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001178	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Association	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	alterations	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	moieties	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	type	_	NOUN	_	Number=Sing	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
15	latency	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	certain	_	ADJ	_	Degree=Pos	_	_	_	_
18	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	replication	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	complex	_	ADJ	_	Degree=Pos	_	_	_	_
17	array	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	virally	_	ADV	_	_	_	_	_	_
20	encoded	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	wide	_	ADJ	_	Degree=Pos	_	_	_	_
3	spectrum	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	various	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	culture	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	vivo	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	replication	_	NOUN	_	Number=Sing	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	differ	_	VERB	_	VerbForm=Inf	_	_	_	_
12	between	_	ADP	_	_	_	_	_	_
13	certain	_	ADJ	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	types	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	now	_	ADV	_	_	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	HIV	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
10	latency	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	line	_	NOUN	_	Number=Sing	_	_	_	_
16	U1	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	only	_	ADV	_	_	_	_	_	_
21	extremely	_	ADV	_	_	_	_	_	_
22	low	_	ADJ	_	Degree=Pos	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	baseline	_	NOUN	_	Number=Sing	_	_	_	_
34	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
35	state	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	alterations	_	NOUN	_	Number=Plur	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
43	factor	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kappa	_	NOUN	_	Number=Sing	_	_	_	_
46	B	_	NOUN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	NF	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	kappa	_	NOUN	_	Number=Sing	_	_	_	_
51	B	_	NOUN	_	Number=Sing	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	moieties	_	NOUN	_	Number=Plur	_	_	_	_
54	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
57	cells	_	NOUN	_	Number=Plur	_	_	_	_
58	by	_	ADP	_	_	_	_	_	_
59	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
60	mobility	_	NOUN	_	Number=Sing	_	_	_	_
61	shift	_	NOUN	_	Number=Sing	_	_	_	_
62	assays	_	NOUN	_	Number=Plur	_	_	_	_
63	(	_	PUNCT	_	_	_	_	_	_
64	EMSAs	_	PROPN	_	Number=Sing	_	_	_	_
65	)	_	PUNCT	_	_	_	_	_	_
66	and	_	CCONJ	_	_	_	_	_	_
67	in	_	ADP	_	_	_	_	_	_
68	situ	_	NOUN	_	Number=Sing	_	_	_	_
69	UV	_	PROPN	_	Number=Sing	_	_	_	_
70	cross	_	VERB	_	Number=Sing	_	_	_	_
71	-	_	PUNCT	_	_	_	_	_	_
72	linking	_	NOUN	_	Number=Sing	_	_	_	_
73	studies	_	NOUN	_	Number=Plur	_	_	_	_
74	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	predominance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p50	_	NUM	_	Number=Sing	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	moieties	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	possibly	_	ADV	_	_	_	_	_	_
12	p50	_	NUM	_	NumType=Card	_	_	_	_
13	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	closely	_	ADV	_	_	_	_	_	_
16	related	_	ADJ	_	Degree=Pos	_	_	_	_
17	species	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	rather	_	ADV	_	_	_	_	_	_
20	than	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	p50-p56	_	NUM	_	NumType=Card	_	_	_	_
23	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	predominant	_	ADJ	_	Degree=Pos	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	species	_	NOUN	_	Number=Plur	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	most	_	ADJ	_	_	_	_	_	_
40	T	_	PROPN	_	Number=Sing	_	_	_	_
41	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
47	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	U1	_	PROPN	_	Number=Sing	_	_	_	_
53	cells	_	NOUN	_	Number=Plur	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	pattern	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	related	_	ADJ	_	Degree=Pos	_	_	_	_
10	moieties	_	NOUN	_	Number=Plur	_	_	_	_
11	differs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	latently	_	ADV	_	_	_	_	_	_
15	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	T	_	NUM	_	Number=Sing	_	_	_	_
17	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	line	_	NOUN	_	Number=Sing	_	_	_	_
20	ACH	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	U937	_	NOUN	_	Number=Sing	_	_	_	_
28	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
29	line	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	parental	_	ADJ	_	Degree=Pos	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	line	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	U1	_	PROPN	_	Number=Sing	_	_	_	_
38	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
39	clone	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	such	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	different	_	ADJ	_	Degree=Pos	_	_	_	_
9	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
10	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	replication	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	various	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	types	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001180	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	DNA	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	activities	_	NOUN	_	Number=Plur	_	_	_	_
8	following	_	VERB	_	VerbForm=Ger	_	_	_	_
9	CD19	_	PROPN	_	Number=Sing	_	_	_	_
10	cross	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	linking	_	VERB	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	lineage	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	B	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	surface	_	NOUN	_	Number=Sing	_	_	_	_
8	molecule	_	NOUN	_	Number=Sing	_	_	_	_
9	CD19	_	PROPN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	all	_	DET	_	_	_	_	_	_
14	stages	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	development	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	including	_	VERB	_	VerbForm=Ger	_	_	_	_
21	normal	_	ADJ	_	Degree=Pos	_	_	_	_
22	plasma	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	mediates	_	VERB	_	Degree=Pos	_	_	_	_
27	signal	_	NOUN	_	Number=Sing	_	_	_	_
28	transduction	_	NOUN	_	Number=Sing	_	_	_	_
29	via	_	ADP	_	_	_	_	_	_
30	interaction	_	NOUN	_	Number=Sing	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
33	effector	_	NOUN	_	Number=Sing	_	_	_	_
34	proteins	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Cross	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
4	CD19	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	early	_	ADJ	_	Degree=Pos	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	lineage	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	formation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	CD19	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	Vav	_	PROPN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	phosphatidylinositol	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	3	_	NUM	_	NumType=Card	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	complex	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	CD19	_	PROPN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	Vav	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	Ras	_	PROPN	_	Number=Sing	_	_	_	_
38	pathway	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	explore	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	ramifications	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CD19	_	PROPN	_	Number=Sing	_	_	_	_
8	signaling	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	current	_	ADJ	_	Degree=Pos	_	_	_	_
12	study	_	NOUN	_	Number=Sing	_	_	_	_
13	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	whether	_	SCONJ	_	_	_	_	_	_
15	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Elk	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	activator	_	NOUN	_	Number=Sing	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	AP	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
37	factor	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	NF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	transcription	_	NOUN	_	Number=Sing	_	_	_	_
46	factors	_	NOUN	_	Number=Plur	_	_	_	_
47	occurred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	following	_	VERB	_	VerbForm=Ger	_	_	_	_
49	CD19	_	PROPN	_	Number=Sing	_	_	_	_
50	cross	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	linking	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	BLIN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	pre	_	X	_	_	_	_	_	_
10	-B	_	PUNCT	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	line	_	NOUN	_	Number=Sing	_	_	_	_
13	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	low	_	ADJ	_	Degree=Pos	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	surface	_	NOUN	_	Number=Sing	_	_	_	_
19	mu	_	PRON	_	_	_	_	_	_
20	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
21	chain	_	NOUN	_	Number=Sing	_	_	_	_
22	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	surrogate	_	ADJ	_	Number=Sing	_	_	_	_
25	light	_	NOUN	_	Number=Sing	_	_	_	_
26	chain	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	1E8	_	NUM	_	NumType=Card	_	_	_	_
30	immature	_	NOUN	_	Degree=Pos	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	line	_	NOUN	_	Number=Sing	_	_	_	_
34	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	surface	_	NOUN	_	Number=Sing	_	_	_	_
37	mu	_	NOUN	_	Number=Sing	_	_	_	_
38	/	_	PUNCT	_	_	_	_	_	_
39	kappa	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Lysates	_	NOUN	_	Number=Plur	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	CD19	_	PROPN	_	Number=Sing	_	_	_	_
4	cross	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	1E8	_	NUM	_	NumType=Card	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	robust	_	ADJ	_	Degree=Pos	_	_	_	_
11	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	Elk	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	fusion	_	NOUN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	vitro	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	whereas	_	SCONJ	_	_	_	_	_	_
23	no	_	DET	_	_	_	_	_	_
24	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	Elk	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	fusion	_	NOUN	_	Number=Sing	_	_	_	_
30	protein	_	NOUN	_	Number=Sing	_	_	_	_
31	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	using	_	VERB	_	VerbForm=Ger	_	_	_	_
33	lysates	_	NOUN	_	Number=Plur	_	_	_	_
34	from	_	ADP	_	_	_	_	_	_
35	CD19	_	PROPN	_	Number=Sing	_	_	_	_
36	cross	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	BLIN	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assay	_	NOUN	_	Number=Sing	_	_	_	_
6	employing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	AP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	consensus	_	NOUN	_	Number=Sing	_	_	_	_
15	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	demonstrate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	AP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	while	_	SCONJ	_	_	_	_	_	_
30	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	binding	_	NOUN	_	Number=Sing	_	_	_	_
36	activity	_	NOUN	_	Number=Sing	_	_	_	_
37	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
38	not	_	PART	_	_	_	_	_	_
39	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	following	_	VERB	_	VerbForm=Ger	_	_	_	_
42	2	_	NUM	_	NumType=Card	_	_	_	_
43	h	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	CD19	_	PROPN	_	Number=Sing	_	_	_	_
46	cross	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	1E8	_	NUM	_	NumType=Card	_	_	_	_
51	cells	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Supershift	_	PROPN	_	Number=Sing	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	JunD	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	c-Fos	_	PROPN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	anti-CD19	_	PROPN	_	Number=Sing	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	AP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	1E8	_	NUM	_	NumType=Card	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	CD19	_	PROPN	_	Number=Sing	_	_	_	_
5	cross	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	linking	_	VERB	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	BLIN	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	no	_	DET	_	_	_	_	_	_
25	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
26	effect	_	NOUN	_	Number=Sing	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	AP	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	activity	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CD19	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	mediated	_	VERB	_	Degree=Pos	_	_	_	_
8	signal	_	NOUN	_	Number=Sing	_	_	_	_
9	transduction	_	NOUN	_	Number=Sing	_	_	_	_
10	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	different	_	ADJ	_	Degree=Pos	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	juxtaposed	_	VERB	_	Degree=Pos	_	_	_	_
16	stages	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	development	_	NOUN	_	Number=Sing	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	may	_	AUX	_	VerbForm=Fin	_	_	_	_
23	culminate	_	VERB	_	VerbForm=Inf	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	suppression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
31	sets	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	genes	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001182	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	[	_	PUNCT	_	_	_	_	_	_
2	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	]	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	most	_	ADJ	_	Degree=Sup	_	_	_	_
3	B	_	ADJ	_	NumType=Card	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	clones	_	NOUN	_	Number=Plur	_	_	_	_
6	immortalized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	EBV	_	PROPN	_	Number=Sing	_	_	_	_
9	virus	_	NOUN	_	Number=Sing	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
15	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	typical	_	ADJ	_	Degree=Pos	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
26	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	role	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	different	_	ADJ	_	Degree=Pos	_	_	_	_
31	elements	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	promoter	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	such	_	ADJ	_	Degree=Pos	_	_	_	_
40	clones	_	NOUN	_	Number=Plur	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	transfection	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	particular	_	ADJ	_	Degree=Pos	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	TCEd	_	VERB	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kB	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	very	_	ADV	_	_	_	_	_	_
24	active	_	ADJ	_	Degree=Pos	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	all	_	DET	_	_	_	_	_	_
27	three	_	NUM	_	NumType=Card	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	clones	_	NOUN	_	Number=Plur	_	_	_	_
30	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	element	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	no	_	DET	_	_	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
12	line	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NFATd	_	ADJ	_	Number=Sing	_	_	_	_
3	element	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	very	_	ADV	_	_	_	_	_	_
16	active	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	only	_	ADV	_	_	_	_	_	_
23	weakly	_	ADV	_	_	_	_	_	_
24	active	_	ADJ	_	Degree=Pos	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	one	_	NUM	_	NumType=Card	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	clone	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	not	_	PART	_	_	_	_	_	_
31	at	_	ADV	_	_	_	_	_	_
32	all	_	ADV	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	another	_	DET	_	_	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Different	_	ADJ	_	Degree=Pos	_	_	_	_
2	elements	_	NOUN	_	Number=Plur	_	_	_	_
3	thus	_	ADV	_	_	_	_	_	_
4	contribute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	different	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001183	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	specificity	_	NOUN	_	Number=Sing	_	_	_	_
6	mutants	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
11	show	_	VERB	_	Number=Sing	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	activator	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	globin	_	NOUN	_	Degree=Pos	_	_	_	_
22	locus	_	NOUN	_	Number=Sing	_	_	_	_
23	control	_	NOUN	_	Number=Sing	_	_	_	_
24	region	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vivo	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	locus	_	NOUN	_	Number=Sing	_	_	_	_
3	control	_	NOUN	_	Number=Sing	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	globin	_	NOUN	_	Number=Sing	_	_	_	_
10	cluster	_	NOUN	_	Number=Sing	_	_	_	_
11	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	five	_	NUM	_	NumType=Card	_	_	_	_
13	DNase	_	NOUN	_	Number=Sing	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	hypersensitive	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	5	_	NUM	_	NumType=Card	_	_	_	_
19	'	_	PUNCT	_	_	_	_	_	_
20	HS1	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	SYM	_	_	_	_	_	_
22	5	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	locus	_	NOUN	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	5'	_	PROPN	_	Number=Sing	_	_	_	_
2	HS3	_	PROPN	_	Number=Sing	_	_	_	_
3	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	six	_	NUM	_	NumType=Card	_	_	_	_
5	G	_	NUM	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	rich	_	ADJ	_	Degree=Pos	_	_	_	_
8	motifs	_	NOUN	_	Number=Plur	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	essential	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Members	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	family	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	three	_	NUM	_	NumType=Card	_	_	_	_
10	zinc	_	NOUN	_	Number=Sing	_	_	_	_
11	fingers	_	NOUN	_	Number=Plur	_	_	_	_
12	highly	_	ADV	_	_	_	_	_	_
13	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
16	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	interact	_	VERB	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
25	motifs	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	point	_	NOUN	_	Number=Sing	_	_	_	_
3	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
4	can	_	AUX	_	VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	distinguish	_	VERB	_	VerbForm=Inf	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	family	_	NOUN	_	Number=Sing	_	_	_	_
9	members	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	which	_	DET	_	PronType=Int	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	activates	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	5'	_	NOUN	_	Number=Sing	_	_	_	_
19	HS3	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	function	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	such	_	ADJ	_	Degree=Pos	_	_	_	_
8	closely	_	ADV	_	_	_	_	_	_
9	related	_	ADJ	_	Degree=Pos	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	can	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	distinguished	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	vivo	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	matching	_	VERB	_	Number=Sing	_	_	_	_
18	point	_	NOUN	_	Number=Sing	_	_	_	_
19	mutations	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	5'	_	NUM	_	Number=Sing	_	_	_	_
22	HS3	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	amino	_	NOUN	_	Degree=Pos	_	_	_	_
25	acid	_	NOUN	_	Number=Sing	_	_	_	_
26	changes	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	zinc	_	NOUN	_	Number=Sing	_	_	_	_
30	fingers	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Testing	_	VERB	_	VerbForm=Ger	_	_	_	_
2	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
6	mice	_	NOUN	_	Number=Plur	_	_	_	_
7	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	direct	_	ADJ	_	Degree=Pos	_	_	_	_
13	activator	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	5'	_	NOUN	_	NumType=Card	_	_	_	_
16	HS3	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001190	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cytomegalovirus	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	HIV	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	often	_	ADV	_	_	_	_	_	_
8	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	latent	_	ADJ	_	Degree=Pos	_	_	_	_
10	infection	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Transactivation	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	some	_	DET	_	_	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	viruses	_	NOUN	_	Number=Plur	_	_	_	_
6	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	SCONJ	_	_	_	_	_	_
10	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	replication	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	IE	_	X	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	X	_	_	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	cytomegalovirus	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	CMV	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	can	_	AUX	_	VerbForm=Fin	_	_	_	_
17	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	as	_	ADV	_	_	_	_	_	_
22	well	_	ADV	_	Degree=Pos	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	HIV	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	vitro	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	inducer	_	NOUN	_	Number=Sing	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	act	_	VERB	_	VerbForm=Inf	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	concert	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	tat	_	NOUN	_	Degree=Pos	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	SCONJ	_	_	_	_	_	_
18	enhancing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	CD4	_	NOUN	_	Number=Sing	_	_	_	_
24	+	_	SYM	_	_	_	_	_	_
25	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	HIV	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	HIV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	tat	_	NOUN	_	Number=Sing	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
14	activators	_	NOUN	_	Number=Plur	_	_	_	_
15	apparently	_	ADV	_	_	_	_	_	_
16	employ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	independent	_	ADJ	_	Degree=Pos	_	_	_	_
18	modes	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	action	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	CMV	_	PROPN	_	Number=Sing	_	_	_	_
24	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	combination	_	NOUN	_	Number=Sing	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	HIV	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	tat	_	NOUN	_	Number=Sing	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
35	activators	_	NOUN	_	Number=Plur	_	_	_	_
36	may	_	AUX	_	VerbForm=Fin	_	_	_	_
37	employ	_	VERB	_	VerbForm=Inf	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	pathway	_	NOUN	_	Number=Sing	_	_	_	_
42	with	_	ADP	_	_	_	_	_	_
43	some	_	DET	_	_	_	_	_	_
44	common	_	ADJ	_	Degree=Pos	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	some	_	DET	_	_	_	_	_	_
47	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
48	components	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	HIV	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	CMV	_	PROPN	_	Number=Sing	_	_	_	_
7	transactivators	_	NOUN	_	Number=Plur	_	_	_	_
8	enhance	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
18	transcript	_	NOUN	_	Number=Sing	_	_	_	_
19	initiation	_	NOUN	_	Number=Sing	_	_	_	_
20	as	_	ADV	_	_	_	_	_	_
21	well	_	ADV	_	Degree=Pos	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	elongation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	CMV	_	PROPN	_	Number=Sing	_	_	_	_
27	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
28	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
29	elongation	_	NOUN	_	Number=Sing	_	_	_	_
30	more	_	ADJ	_	Degree=Cmp	_	_	_	_
31	than	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	initiation	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	significant	_	ADJ	_	Degree=Pos	_	_	_	_
3	proportion	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
6	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	terminate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	prematurely	_	ADV	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	absence	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	transactivators	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	PROPN	_	Number=Sing	_	_	_	_
2	mutation	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	HIV	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	long	_	ADJ	_	Degree=Pos	_	_	_	_
10	terminal	_	NOUN	_	Number=Sing	_	_	_	_
11	repeat	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	LTR	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	element	_	NOUN	_	Number=Sing	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	responds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	CMV	_	PROPN	_	Number=Sing	_	_	_	_
23	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	CD4	_	NOUN	_	Number=Sing	_	_	_	_
27	+	_	SYM	_	_	_	_	_	_
28	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	either	_	CCONJ	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	diffuse	_	NOUN	_	Degree=Pos	_	_	_	_
33	one	_	NUM	_	NumType=Card	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	downstream	_	ADP	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	HIV	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
43	element	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001192	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tissue	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	platelet	_	NOUN	_	Number=Sing	_	_	_	_
8	GPIIb	_	PROPN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	major	_	ADJ	_	Degree=Pos	_	_	_	_
5	objectives	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	study	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	thrombogenesis	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
20	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	committed	_	ADJ	_	Degree=Pos	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
28	lineage	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	development	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	primary	_	ADJ	_	Degree=Pos	_	_	_	_
5	cultures	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	megakaryocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
12	cloning	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	lineage	_	NOUN	_	Number=Sing	_	_	_	_
21	offer	_	VERB	_	VerbForm=Inf	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	possibility	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	SCONJ	_	_	_	_	_	_
25	getting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	some	_	DET	_	_	_	_	_	_
27	insights	_	NOUN	_	Number=Plur	_	_	_	_
28	into	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
31	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
32	that	_	PRON	_	PronType=Rel	_	_	_	_
33	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	megakaryocytopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	interest	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
8	IIb	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	GPIIb	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	;	_	PUNCT	_	_	_	_	_	_
14	GPIIb	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	subunit	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	platelet	_	NOUN	_	Number=Sing	_	_	_	_
22	cytoadhesin	_	NOUN	_	Number=Sing	_	_	_	_
23	GPIIb	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	IIIa	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	megakaryocytes	_	NOUN	_	Number=Plur	_	_	_	_
31	at	_	ADP	_	_	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	early	_	ADJ	_	Degree=Pos	_	_	_	_
34	stage	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	whereas	_	SCONJ	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	other	_	ADJ	_	Degree=Pos	_	_	_	_
42	subunit	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
45	complex	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	GPIIIa	_	PROPN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
50	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
51	in	_	ADP	_	_	_	_	_	_
52	other	_	ADJ	_	Degree=Pos	_	_	_	_
53	cells	_	NOUN	_	Number=Plur	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	reasons	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	5	_	NUM	_	NumType=Card	_	_	_	_
7	'-	_	PUNCT	_	_	_	_	_	_
8	flanking	_	VERB	_	Number=Sing	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	GPIIb	_	PROPN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	regions	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	DNA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
26	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	factors	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	fragment	_	NOUN	_	Number=Sing	_	_	_	_
3	extending	_	VERB	_	VerbForm=Ger	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	-	_	SYM	_	_	_	_	_	_
6	643	_	NUM	_	NumType=Card	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	+	_	SYM	_	_	_	_	_	_
9	33	_	NUM	_	NumType=Card	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	capable	_	ADJ	_	Degree=Pos	_	_	_	_
12	of	_	SCONJ	_	_	_	_	_	_
13	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	tissue	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	CAT	_	NOUN	_	Number=Sing	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	transfection	_	NOUN	_	Number=Sing	_	_	_	_
25	experiments	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Within	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	several	_	ADJ	_	Degree=Pos	_	_	_	_
9	sequences	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	DNA	_	PROPN	_	Number=Sing	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	interactions	_	NOUN	_	Number=Plur	_	_	_	_
17	as	_	SCONJ	_	_	_	_	_	_
18	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	DNAse	_	NOUN	_	Number=Sing	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	footprints	_	VERB	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	gel	_	NOUN	_	Number=Sing	_	_	_	_
25	mobility	_	NOUN	_	Number=Sing	_	_	_	_
26	shift	_	NOUN	_	Number=Sing	_	_	_	_
27	assays	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	centered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	-	_	SYM	_	_	_	_	_	_
7	54	_	NUM	_	NumType=Card	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	similar	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	E1	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	region	_	NOUN	_	Number=Sing	_	_	_	_
23	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	at	_	ADP	_	_	_	_	_	_
25	position	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	233	_	NUM	_	NumType=Card	_	_	_	_
28	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	CCAAT	_	NOUN	_	Number=Sing	_	_	_	_
31	motif	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	domains	_	NOUN	_	Number=Plur	_	_	_	_
3	centered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	at	_	ADP	_	_	_	_	_	_
5	positions	_	NOUN	_	Number=Plur	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	345	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	-	_	SYM	_	_	_	_	_	_
10	540	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	respectively	_	ADV	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	bind	_	VERB	_	Number=Sing	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	present	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	nonrelated	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	as	_	ADV	_	_	_	_	_	_
26	well	_	ADV	_	Degree=Pos	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	two	_	NUM	_	NumType=Card	_	_	_	_
4	other	_	ADJ	_	Degree=Pos	_	_	_	_
5	domains	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	at	_	ADP	_	_	_	_	_	_
9	positions	_	NOUN	_	Number=Plur	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	460	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	510	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	interact	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	only	_	ADV	_	_	_	_	_	_
22	present	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	deletion	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	domains	_	NOUN	_	Number=Plur	_	_	_	_
12	results	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	significant	_	ADJ	_	Degree=Pos	_	_	_	_
16	decrease	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	very	_	ADV	_	_	_	_	_	_
4	likely	_	ADJ	_	Degree=Pos	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	domains	_	NOUN	_	Number=Plur	_	_	_	_
8	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	megakaryocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	positive	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001196	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	Nef	_	PROPN	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	long	_	ADJ	_	Degree=Pos	_	_	_	_
8	terminal	_	NOUN	_	Number=Sing	_	_	_	_
9	repeat	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	HIV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	LTR	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	sites	_	NOUN	_	Number=Plur	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	several	_	ADJ	_	Degree=Pos	_	_	_	_
22	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factors	_	NOUN	_	Number=Plur	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	contribute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	HIV	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	previous	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	function	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	HIV	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1-	_	NUM	_	_	_	_	_	_
12	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	Nef	_	PROPN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	Nef	_	PROPN	_	Number=Sing	_	_	_	_
18	may	_	AUX	_	VerbForm=Fin	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	Nef	_	PROPN	_	Number=Sing	_	_	_	_
5	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	implicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	32P	_	NUM	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	labeled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
22	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	sites	_	NOUN	_	Number=Plur	_	_	_	_
27	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	incubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
31	extracts	_	NOUN	_	Number=Plur	_	_	_	_
32	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	from	_	ADP	_	_	_	_	_	_
34	Nef	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
37	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
38	lines	_	NOUN	_	Number=Plur	_	_	_	_
39	that	_	PRON	_	PronType=Rel	_	_	_	_
40	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	not	_	PART	_	_	_	_	_	_
42	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	or	_	CCONJ	_	_	_	_	_	_
44	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
45	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
46	with	_	ADP	_	_	_	_	_	_
47	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
48	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	Nef	_	PROPN	_	Number=Sing	_	_	_	_
5	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	DNA	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_

1	Nef	_	NOUN	_	Number=Sing	_	_	_	_
2	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	transiently	_	ADV	_	_	_	_	_	_
6	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	DNA	_	NOUN	_	Number=Sing	_	_	_	_
19	recognition	_	NOUN	_	Number=Sing	_	_	_	_
20	sequences	_	NOUN	_	Number=Plur	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
27	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	CAT	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Mitogen	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	CAT	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
12	construct	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	Nef	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	control	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	by	_	SCONJ	_	_	_	_	_	_
7	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
8	AP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	Nef	_	PROPN	_	Number=Sing	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	play	_	VERB	_	VerbForm=Inf	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	SCONJ	_	_	_	_	_	_
19	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001200	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cyclosporin	_	VERB	_	Number=Sing	_	_	_	_
2	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	inhibits	_	NOUN	_	Number=Sing	_	_	_	_
4	early	_	ADJ	_	Degree=Pos	_	_	_	_
5	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	G0	_	PROPN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	G1	_	NOUN	_	Number=Sing	_	_	_	_
11	switch	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	G0S2	_	NOUN	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	cultured	_	VERB	_	Degree=Pos	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	blood	_	NOUN	_	Number=Sing	_	_	_	_
21	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Cyclosporin	_	PROPN	_	Number=Sing	_	_	_	_
2	A	_	PROPN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	CsA	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	achieve	_	VERB	_	VerbForm=Inf	_	_	_	_
8	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
9	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
10	effects	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	SCONJ	_	_	_	_	_	_
12	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	calcium	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	calmodulin	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
21	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	target	_	NOUN	_	Number=Sing	_	_	_	_
29	genes	_	NOUN	_	Number=Plur	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	members	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
37	factor	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	T	_	NOUN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	transcription	_	NOUN	_	Number=Sing	_	_	_	_
44	factor	_	NOUN	_	Number=Sing	_	_	_	_
45	family	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Among	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	target	_	NOUN	_	Number=Sing	_	_	_	_
4	genes	_	NOUN	_	Number=Plur	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	encoding	_	VERB	_	Number=Sing	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IL2	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
18	facilitating	_	VERB	_	VerbForm=Ger	_	_	_	_
19	progression	_	NOUN	_	Number=Sing	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	G1	_	NOUN	_	Number=Sing	_	_	_	_
23	phase	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	cycle	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IL2	_	PROPN	_	Number=Sing	_	_	_	_
4	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	reverse	_	VERB	_	VerbForm=Inf	_	_	_	_
7	CsA	_	PROPN	_	Number=Sing	_	_	_	_
8	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	at	_	ADV	_	_	_	_	_	_
13	least	_	ADV	_	Degree=Sup	_	_	_	_
14	one	_	NUM	_	NumType=Card	_	_	_	_
15	other	_	ADJ	_	Degree=Pos	_	_	_	_
16	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	involved	_	ADJ	_	Degree=Pos	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	G0	_	NOUN	_	Number=Sing	_	_	_	_
4	/	_	PUNCT	_	_	_	_	_	_
5	G1	_	NOUN	_	Number=Sing	_	_	_	_
6	switch	_	NOUN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	G0S2	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	potential	_	ADJ	_	Degree=Pos	_	_	_	_
13	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	5	_	NUM	_	NumType=Card	_	_	_	_
20	'	_	PUNCT	_	_	_	_	_	_
21	flank	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	small	_	ADJ	_	Degree=Pos	_	_	_	_
26	basic	_	ADJ	_	Degree=Pos	_	_	_	_
27	potential	_	ADJ	_	Degree=Pos	_	_	_	_
28	phosphoprotein	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
31	function	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	reverse	_	NOUN	_	Degree=Pos	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
9	chain	_	NOUN	_	Number=Sing	_	_	_	_
10	reaction	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	RT	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	PCR	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	assay	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	G0S2	_	PROPN	_	Number=Sing	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	levels	_	NOUN	_	Number=Plur	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	assayed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	blood	_	NOUN	_	Number=Sing	_	_	_	_
26	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Freshly	_	ADV	_	_	_	_	_	_
2	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	high	_	ADJ	_	Degree=Pos	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	G0S2	_	NOUN	_	Number=Sing	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	rapidly	_	ADV	_	_	_	_	_	_
12	decline	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	"	_	PUNCT	_	_	_	_	_	_
3	spontaneous	_	ADJ	_	Degree=Pos	_	_	_	_
4	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
5	"	_	PUNCT	_	_	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	noted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	some	_	DET	_	_	_	_	_	_
11	other	_	ADJ	_	Degree=Pos	_	_	_	_
12	G0S	_	PROPN	_	Number=Sing	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	attributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	some	_	DET	_	_	_	_	_	_
20	aspect	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	isolation	_	NOUN	_	Number=Sing	_	_	_	_
24	procedure	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	that	_	PRON	_	PronType=Rel	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
6	preincubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	there	_	PRON	_	_	_	_	_	_
13	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	transient	_	ADJ	_	Degree=Pos	_	_	_	_
16	increase	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	G0S2	_	PROPN	_	Number=Sing	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	peaking	_	VERB	_	Number=Sing	_	_	_	_
22	between	_	ADP	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	SYM	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	h	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	response	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	Concanavalin	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	A	_	PROPN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	ConA	_	PROPN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	combination	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
44	ester	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	TPA	_	NOUN	_	Number=Sing	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	calcium	_	NOUN	_	Number=Sing	_	_	_	_
52	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	ionomycin	_	PROPN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	responses	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	CsA	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	G0S2	_	PROPN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	commit	_	VERB	_	VerbForm=Inf	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	enter	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	G1	_	NUM	_	Number=Sing	_	_	_	_
16	phase	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	cycle	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	while	_	SCONJ	_	_	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	excluding	_	VERB	_	VerbForm=Ger	_	_	_	_
28	other	_	ADJ	_	Degree=Pos	_	_	_	_
29	possible	_	ADJ	_	Degree=Pos	_	_	_	_
30	targets	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	early	_	ADJ	_	Degree=Pos	_	_	_	_
33	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	G0S2	_	PROPN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	CsA	_	PROPN	_	Number=Sing	_	_	_	_
39	may	_	AUX	_	VerbForm=Fin	_	_	_	_
40	be	_	AUX	_	VerbForm=Inf	_	_	_	_
41	important	_	ADJ	_	Degree=Pos	_	_	_	_
42	in	_	SCONJ	_	_	_	_	_	_
43	achieving	_	VERB	_	VerbForm=Ger	_	_	_	_
44	immunosuppression	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	G0S2	_	NOUN	_	Number=Sing	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	be	_	AUX	_	VerbForm=Inf	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	value	_	NOUN	_	Number=Sing	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	reporter	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	SCONJ	_	_	_	_	_	_
11	analyzing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	action	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	CsA	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	influence	_	NOUN	_	Number=Sing	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	positive	_	ADJ	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	negative	_	ADJ	_	Degree=Pos	_	_	_	_
26	selection	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	response	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	self	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	not	_	ADV	_	_	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	self	_	NOUN	_	Number=Sing	_	_	_	_
37	antigens	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001202	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	ETS1	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	AP1	_	NOUN	_	Number=Sing	_	_	_	_
6	synergistically	_	ADV	_	_	_	_	_	_
7	transactivate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	GM	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	CSF	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	helper	_	NOUN	_	Number=Sing	_	_	_	_
4	T	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	results	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	coordinate	_	ADJ	_	Degree=Pos	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	number	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
15	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	haematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
25	system	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
4	colony	_	NOUN	_	Number=Sing	_	_	_	_
5	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	GM	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CSF	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	one	_	NUM	_	NumType=Card	_	_	_	_
14	such	_	ADJ	_	Degree=Pos	_	_	_	_
15	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
18	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	results	_	NOUN	_	Number=Plur	_	_	_	_
21	mostly	_	ADV	_	_	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	increases	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Cis	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	acting	_	VERB	_	Number=Sing	_	_	_	_
4	elements	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	AP1	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	ETS	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	like	_	SCONJ	_	Degree=Pos	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	motifs	_	NOUN	_	Number=Plur	_	_	_	_
15	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	promoter	_	ADJ	_	Number=Sing	_	_	_	_
21	region	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	GM	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	CSF	_	PROPN	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	important	_	ADJ	_	Degree=Pos	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	essential	_	ADJ	_	Degree=Pos	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
36	activity	_	NOUN	_	Number=Sing	_	_	_	_
37	following	_	VERB	_	VerbForm=Ger	_	_	_	_
38	T	_	NOUN	_	Number=Sing	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	ETS1	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	ETS	_	NOUN	_	Number=Sing	_	_	_	_
9	family	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	ETS1	_	PROPN	_	Number=Sing	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	GM	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	CSF	_	PROPN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	only	_	ADV	_	_	_	_	_	_
19	after	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	treatment	_	NOUN	_	Number=Sing	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	PMA	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	ionomycin	_	PROPN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	agents	_	NOUN	_	Number=Plur	_	_	_	_
33	that	_	PRON	_	PronType=Rel	_	_	_	_
34	mimic	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	T	_	NOUN	_	Number=Sing	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	proposed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	ETS1	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	constitutively	_	ADV	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	act	_	VERB	_	VerbForm=Inf	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	concert	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	PMA	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
23	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
24	factors	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	ETS1	_	PROPN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	GM	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	CSF	_	NOUN	_	Number=Sing	_	_	_	_
12	reporter	_	NOUN	_	Number=Sing	_	_	_	_
13	construct	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
16	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	providing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	either	_	CCONJ	_	_	_	_	_	_
22	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	AP1	_	NOUN	_	Number=Sing	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	factors	_	NOUN	_	Number=Plur	_	_	_	_
27	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	supplied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	co-transfection	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	confirm	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	DET	_	_	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
7	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	AP1	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	following	_	VERB	_	VerbForm=Ger	_	_	_	_
13	PMA	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	ionomycin	_	NOUN	_	Degree=Pos	_	_	_	_
16	treatment	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	T	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Transactivation	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	ETS1	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	AP1	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	mutation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	individual	_	ADJ	_	Degree=Pos	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	sites	_	NOUN	_	Number=Plur	_	_	_	_
18	reveals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	activities	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
25	factors	_	NOUN	_	Number=Plur	_	_	_	_
26	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	interdependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
6	ETS1	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
10	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	AP1	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	cooperate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	part	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
20	order	_	NOUN	_	Number=Sing	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	complex	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001205	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Synergism	_	NOUN	_	Number=Sing	_	_	_	_
2	between	_	ADP	_	_	_	_	_	_
3	two	_	NUM	_	NumType=Card	_	_	_	_
4	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	enhancer	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	during	_	ADP	_	_	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	trans	_	NOUN	_	Number=Plur	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	activator	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	conducted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	functional	_	ADJ	_	Degree=Pos	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
9	elements	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
13	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	type	_	NOUN	_	Number=Sing	_	_	_	_
16	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	using	_	VERB	_	VerbForm=Ger	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
26	lines	_	NOUN	_	Number=Plur	_	_	_	_
27	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	MOLT	_	PROPN	_	Number=Sing	_	_	_	_
30	4	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	negative	_	ADJ	_	Degree=Pos	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	I	_	PROPN	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	MT	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	2	_	NUM	_	NumType=Card	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	TL	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	Mor	_	PROPN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	which	_	PRON	_	PronType=Rel	_	_	_	_
50	carry	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
53	genome	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
3	elements	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
6	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	function	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	enhancer	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	One	_	PRON	_	_	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	21-	_	NUM	_	NumType=Card	_	_	_	_
5	base	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	pair	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	bp	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	core	_	NOUN	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	trans	_	NOUN	_	Number=Plur	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	trans	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	activator	_	NOUN	_	Number=Sing	_	_	_	_
28	p40tax	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
31	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	ability	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	cyclic	_	ADJ	_	VerbForm=Inf	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	AMP	_	NOUN	_	_	_	_	_	_
40	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
41	element	_	NOUN	_	Number=Sing	_	_	_	_
42	binding	_	NOUN	_	Number=Sing	_	_	_	_
43	factor	_	NOUN	_	Number=Sing	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	CREB	_	NOUN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	like	_	ADJ	_	Degree=Pos	_	_	_	_
49	factor	_	NOUN	_	Number=Sing	_	_	_	_
50	(	_	PUNCT	_	_	_	_	_	_
51	s	_	X	_	_	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	region	_	NOUN	_	Number=Sing	_	_	_	_
6	interposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	21	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	bp	_	NOUN	_	Number=Sing	_	_	_	_
12	elements	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	subfragment	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	C26	_	X	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	region	_	NOUN	_	Number=Sing	_	_	_	_
15	between	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	21	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	bp	_	NOUN	_	Number=Sing	_	_	_	_
20	elements	_	NOUN	_	Number=Plur	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	involved	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	trans	_	NOUN	_	Number=Plur	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	p40tax	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	possibly	_	ADV	_	_	_	_	_	_
31	through	_	ADP	_	_	_	_	_	_
32	binding	_	VERB	_	Number=Sing	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	like	_	ADP	_	_	_	_	_	_
41	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
42	factor	_	NOUN	_	Number=Sing	_	_	_	_
43	or	_	CCONJ	_	_	_	_	_	_
44	factors	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Formation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	complex	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	C26	_	PROPN	_	Number=Sing	_	_	_	_
11	subfragment	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	positively	_	ADV	_	_	_	_	_	_
14	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	p40tax	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	C26	_	PROPN	_	Number=Sing	_	_	_	_
3	element	_	NOUN	_	Number=Sing	_	_	_	_
4	conferred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	partial	_	ADJ	_	Degree=Pos	_	_	_	_
6	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	p40tax	_	NOUN	_	VerbForm=Inf	_	_	_	_
9	when	_	ADV	_	PronType=Int	_	_	_	_
10	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	one	_	NUM	_	NumType=Card	_	_	_	_
13	copy	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	21	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	bp	_	NOUN	_	Number=Sing	_	_	_	_
19	element	_	NOUN	_	Number=Sing	_	_	_	_
20	that	_	PRON	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	itself	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs|Reflex=Yes	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	little	_	ADJ	_	Degree=Pos	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	response	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	p40tax	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	C26	_	PROPN	_	Number=Sing	_	_	_	_
5	element	_	NOUN	_	Number=Sing	_	_	_	_
6	alone	_	ADV	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	even	_	ADV	_	_	_	_	_	_
9	when	_	ADV	_	PronType=Int	_	_	_	_
10	repeated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	could	_	AUX	_	VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	p40tax	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	unlike	_	ADP	_	_	_	_	_	_
20	other	_	ADJ	_	Degree=Pos	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	elements	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	C26	_	NOUN	_	Number=Sing	_	_	_	_
6	element	_	NOUN	_	Number=Sing	_	_	_	_
7	itself	_	PRON	_	Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	profoundly	_	ADV	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	upon	_	ADP	_	_	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	12	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	O-tetradecanoylphorbol	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	13	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	acetate	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	therefore	_	ADV	_	_	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	enhancer	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
13	functional	_	ADJ	_	Degree=Pos	_	_	_	_
14	elements	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	including	_	VERB	_	VerbForm=Ger	_	_	_	_
17	binding	_	NOUN	_	Degree=Pos	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	at	_	ADV	_	_	_	_	_	_
21	least	_	ADV	_	Degree=Sup	_	_	_	_
22	CREB	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	PROPN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	like	_	ADP	_	Degree=Pos	_	_	_	_
31	factors	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	which	_	PRON	_	PronType=Rel	_	_	_	_
34	synergistically	_	ADV	_	_	_	_	_	_
35	cooperate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
43	enhancer	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	response	_	NOUN	_	Number=Sing	_	_	_	_
46	to	_	ADP	_	_	_	_	_	_
47	p40tax	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	TPA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	through	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	C26	_	NOUN	_	Number=Sing	_	_	_	_
22	element	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001208	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	sialoadhesin	_	NOUN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	rat	_	NOUN	_	Number=Sing	_	_	_	_
7	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	beta	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	IFN	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	4	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Sialoadhesin	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	member	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	Ig	_	PROPN	_	Number=Sing	_	_	_	_
11	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	subpopulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
11	tissues	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
15	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	e.g.	_	X	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	during	_	ADP	_	_	_	_	_	_
20	autoimmune	_	NOUN	_	Number=Sing	_	_	_	_
21	diseases	_	NOUN	_	Number=Plur	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	sialoadhesin	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vitro	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	glucocorticoids	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	GC	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
19	sialoadhesin	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	freshly	_	ADV	_	_	_	_	_	_
23	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	rat	_	NOUN	_	Number=Sing	_	_	_	_
25	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	rat	_	NOUN	_	Number=Sing	_	_	_	_
29	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	line	_	NOUN	_	Number=Sing	_	_	_	_
32	R2	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cytokines	_	PROPN	_	Number=Plur	_	_	_	_
3	IFN	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	gamma	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	LPS	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	although	_	SCONJ	_	_	_	_	_	_
19	unable	_	ADJ	_	Degree=Pos	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
22	sialoadhesin	_	NOUN	_	Degree=Pos	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	themselves	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs|Reflex=Yes	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	able	_	ADJ	_	Degree=Pos	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
31	GC	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	mediated	_	VERB	_	Degree=Pos	_	_	_	_
34	induction	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	sialoadhesin	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Sialoadhesin	_	PROPN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	functional	_	ADJ	_	Degree=Pos	_	_	_	_
5	as	_	SCONJ	_	_	_	_	_	_
6	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
10	assays	_	NOUN	_	Number=Plur	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	RBCs	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blotting	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	predominantly	_	ADV	_	_	_	_	_	_
8	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
12	level	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Comparison	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	different	_	ADJ	_	Degree=Pos	_	_	_	_
5	combinations	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	GC	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	LPS	_	PROPN	_	Number=Sing	_	_	_	_
12	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	differences	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	level	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	GC	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
21	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	sialoadhesin	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	IFN	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	beta	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	4	_	NUM	_	NumType=Card	_	_	_	_
34	being	_	AUX	_	VerbForm=Ger	_	_	_	_
35	more	_	ADV	_	_	_	_	_	_
36	potent	_	ADJ	_	Degree=Pos	_	_	_	_
37	than	_	ADP	_	_	_	_	_	_
38	IFN	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	gamma	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	LPS	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	LPS	_	NOUN	_	Number=Sing	_	_	_	_
11	could	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	reproduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	priming	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	whereas	_	SCONJ	_	_	_	_	_	_
18	IFN	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	beta	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	simultaneously	_	ADV	_	_	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	GC	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	sialoadhesin	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	GC	_	NOUN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	mineralocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	as	_	SCONJ	_	_	_	_	_	_
20	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
23	experiments	_	NOUN	_	Number=Plur	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	antagonists	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	adrenal	_	ADJ	_	Degree=Pos	_	_	_	_
11	gland	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	major	_	ADJ	_	Degree=Pos	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
18	GC	_	NOUN	_	Number=Sing	_	_	_	_
19	production	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	express	_	ADJ	_	Degree=Pos	_	_	_	_
22	sialoadhesin	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	GC	_	PROPN	_	Number=Sing	_	_	_	_
6	act	_	VERB	_	Number=Sing	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	inducer	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	sialoadhesin	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	rat	_	NOUN	_	Number=Sing	_	_	_	_
16	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	can	_	AUX	_	VerbForm=Fin	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	IFN	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	beta	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	T	_	PROPN	_	Number=Sing	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	or	_	CCONJ	_	_	_	_	_	_
37	LPS	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001209	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
6	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	killer	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	patients	_	NOUN	_	Number=Sing	_	_	_	_
13	receiving	_	VERB	_	VerbForm=Ger	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	immunotherapy	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Administration	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	can	_	AUX	_	VerbForm=Fin	_	_	_	_
14	result	_	VERB	_	VerbForm=Inf	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
17	benefits	_	NOUN	_	Number=Plur	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	individuals	_	NOUN	_	Number=Plur	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	renal	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	melanoma	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	families	_	NOUN	_	Number=Plur	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	signal	_	NOUN	_	Number=Sing	_	_	_	_
23	transducers	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	activators	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	STAT	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	cancer	_	NOUN	_	Number=Sing	_	_	_	_
33	patients	_	NOUN	_	Number=Plur	_	_	_	_
34	'	_	PART	_	_	_	_	_	_
35	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
36	before	_	ADV	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	after	_	ADP	_	_	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	immunotherapy	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	as	_	SCONJ	_	_	_	_	_	_
45	assessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	by	_	ADP	_	_	_	_	_	_
47	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
48	gel	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	shift	_	NOUN	_	Number=Sing	_	_	_	_
51	assay	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	vitro	_	ADJ	_	Number=Sing	_	_	_	_
4	surrogate	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	immunotherapy	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	incubation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	fresh	_	ADJ	_	Degree=Pos	_	_	_	_
15	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
16	blood	_	NOUN	_	Number=Sing	_	_	_	_
17	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
24	individuals	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	several	_	ADJ	_	Degree=Pos	_	_	_	_
31	days	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	production	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	killer	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	LAK	_	PROPN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	activity	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
48	cultures	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	purpose	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	describe	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	profile	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
17	different	_	ADJ	_	Degree=Pos	_	_	_	_
18	populations	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	assess	_	VERB	_	VerbForm=Inf	_	_	_	_
22	whether	_	SCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	patterns	_	NOUN	_	Number=Plur	_	_	_	_
25	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	correlated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	functional	_	ADJ	_	Degree=Pos	_	_	_	_
29	differences	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Prior	_	ADJ	_	Degree=Pos	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vivo	_	PROPN	_	Number=Sing	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	administration	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	typical	_	ADJ	_	Degree=Pos	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	pattern	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	patients	_	NOUN	_	Number=Sing	_	_	_	_
21	resembled	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	that	_	PRON	_	_	_	_	_	_
23	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	fresh	_	ADJ	_	Degree=Pos	_	_	_	_
26	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
29	individuals	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Over	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	week	_	NOUN	_	Number=Sing	_	_	_	_
6	course	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	therapy	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	most	_	ADJ	_	Degree=Sup	_	_	_	_
15	patients	_	NOUN	_	Number=Plur	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	patterns	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	changed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	resemble	_	VERB	_	VerbForm=Inf	_	_	_	_
34	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
35	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
38	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	2	_	NUM	_	NumType=Card	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	vitro	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	obtained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	patients	_	NOUN	_	Number=Plur	_	_	_	_
13	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	have	_	VERB	_	VerbForm=Inf	_	_	_	_
16	low	_	ADJ	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	level	_	NOUN	_	Number=Sing	_	_	_	_
19	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	STAT	_	NOUN	_	Number=Sing	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	factors	_	NOUN	_	Number=Plur	_	_	_	_
25	as	_	SCONJ	_	_	_	_	_	_
26	did	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	LAK	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	patient	_	NOUN	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	further	_	ADV	_	_	_	_	_	_
7	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vitro	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	additional	_	ADJ	_	Degree=Pos	_	_	_	_
16	differences	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	STAT	_	PROPN	_	Number=Sing	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	patterns	_	NOUN	_	Number=Plur	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	noted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	further	_	ADJ	_	Degree=Pos	_	_	_	_
5	information	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
9	events	_	NOUN	_	Number=Plur	_	_	_	_
10	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	immune	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	vivo	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	vitro	_	NOUN	_	Number=Sing	_	_	_	_
21	administration	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	further	_	ADJ	_	Degree=Pos	_	_	_	_
29	document	_	NOUN	_	Number=Sing	_	_	_	_
30	that	_	SCONJ	_	_	_	_	_	_
31	there	_	PRON	_	_	_	_	_	_
32	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	not	_	PART	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	precise	_	ADJ	_	Degree=Pos	_	_	_	_
36	congruence	_	NOUN	_	Number=Sing	_	_	_	_
37	between	_	ADP	_	_	_	_	_	_
38	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
39	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	vivo	_	NOUN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	vitro	_	NOUN	_	Number=Sing	_	_	_	_
45	by	_	ADP	_	_	_	_	_	_
46	IL	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	2	_	NUM	_	NumType=Card	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_
50	Document	_	NOUN	_	Number=Sing	_	_	_	_
51	003001214	_	NUM	_	NumType=Card	_	_	_	_
52	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Positive	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	negative	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	novel	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
18	element	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	new	_	ADJ	_	Degree=Pos	_	_	_	_
3	B-cell	_	X	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	3'	_	NUM	_	_	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	E4	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	octamerlike	_	NOUN	_	Degree=Pos	_	_	_	_
17	motifs	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
22	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	chain	_	NOUN	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Tandem	_	NOUN	_	Number=Sing	_	_	_	_
2	copies	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	67	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	bp	_	NOUN	_	Number=Sing	_	_	_	_
8	MnlI	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	AluI	_	PROPN	_	Number=Sing	_	_	_	_
11	fragment	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	when	_	ADV	_	PronType=Rel	_	_	_	_
14	fused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
18	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	conalbumin	_	NOUN	_	Number=Sing	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	B	_	ADJ	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	but	_	CCONJ	_	_	_	_	_	_
32	not	_	PART	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
35	T	_	PROPN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Footprinting	_	NOUN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	identical	_	ADJ	_	Degree=Pos	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	CCGAAACTGAAAAGG	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	E6	_	NUM	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	protected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	extracts	_	NOUN	_	Number=Plur	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	B	_	ADJ	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	using	_	VERB	_	VerbForm=Ger	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
8	E6	_	NUM	_	Number=Sing	_	_	_	_
9	motif	_	NOUN	_	Number=Sing	_	_	_	_
10	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	B	_	NUM	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	complex	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	addition	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
23	band	_	NOUN	_	Number=Sing	_	_	_	_
24	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	also	_	ADV	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	T	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	agreement	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	gel	_	NOUN	_	Number=Sing	_	_	_	_
8	retardation	_	NOUN	_	Number=Sing	_	_	_	_
9	assays	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	tandem	_	NOUN	_	Number=Sing	_	_	_	_
12	copies	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	E6	_	NUM	_	Number=Sing	_	_	_	_
16	motif	_	NOUN	_	Number=Sing	_	_	_	_
17	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	ARH77	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	Raji	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	mutant	_	ADJ	_	Number=Sing	_	_	_	_
5	E6	_	NUM	_	Number=Sing	_	_	_	_
6	motif	_	NOUN	_	Number=Sing	_	_	_	_
7	lost	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vitro	_	ADJ	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	vivo	_	ADJ	_	Number=Sing	_	_	_	_
16	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	striking	_	ADJ	_	VerbForm=Ger	_	_	_	_
3	contrast	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	mouse	_	NOUN	_	Number=Sing	_	_	_	_
7	Ig	_	NOUN	_	_	_	_	_	_
8	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	chain	_	NOUN	_	Number=Sing	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	octamer	_	ADJ	_	Number=Sing	_	_	_	_
17	motif	_	NOUN	_	Number=Sing	_	_	_	_
18	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	B	_	NUM	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
27	element	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
32	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	octamerlike	_	NOUN	_	Degree=Pos	_	_	_	_
35	sequence	_	NOUN	_	Number=Sing	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	one	_	NUM	_	NumType=Card	_	_	_	_
38	base	_	NOUN	_	Number=Sing	_	_	_	_
39	substitution	_	NOUN	_	Number=Sing	_	_	_	_
40	which	_	PRON	_	PronType=Rel	_	_	_	_
41	bound	_	VERB	_	Degree=Pos	_	_	_	_
42	octamer	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	binding	_	VERB	_	Number=Sing	_	_	_	_
45	proteins	_	NOUN	_	Number=Plur	_	_	_	_
46	with	_	ADP	_	_	_	_	_	_
47	only	_	ADV	_	_	_	_	_	_
48	very	_	ADV	_	_	_	_	_	_
49	low	_	ADJ	_	Degree=Pos	_	_	_	_
50	affinity	_	NOUN	_	Number=Sing	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
53	no	_	DET	_	_	_	_	_	_
54	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
55	activity	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
58	own	_	ADJ	_	Degree=Pos	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	MnlI	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	AluI	_	PROPN	_	Number=Sing	_	_	_	_
7	fragment	_	NOUN	_	Number=Sing	_	_	_	_
8	could	_	AUX	_	VerbForm=Fin	_	_	_	_
9	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	basal	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	level	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	conalbumin	_	NOUN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	simian	_	ADJ	_	Degree=Pos	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	40	_	NUM	_	NumType=Card	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	MnlI	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	AluI	_	PROPN	_	Number=Sing	_	_	_	_
15	fragment	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	B	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
6	element	_	NOUN	_	Number=Sing	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	study	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	probably	_	ADV	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	target	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	positive	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	negative	_	ADJ	_	Degree=Pos	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001215	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	family	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	serine	_	NOUN	_	Number=Sing	_	_	_	_
5	proteases	_	NOUN	_	Number=Plur	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	exclusively	_	ADV	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	myelo	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	specifically	_	ADV	_	_	_	_	_	_
14	processes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	subunit	_	NOUN	_	Number=Sing	_	_	_	_
22	p65	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	vitro	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	may	_	AUX	_	VerbForm=Fin	_	_	_	_
27	impair	_	VERB	_	VerbForm=Inf	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
30	virus	_	NOUN	_	Number=Sing	_	_	_	_
31	replication	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	groups	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	U937	_	NOUN	_	Number=Sing	_	_	_	_
5	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	limiting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	dilution	_	NOUN	_	Number=Sing	_	_	_	_
12	cloning	_	NOUN	_	Number=Sing	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	differed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	strikingly	_	ADV	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	ability	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	support	_	VERB	_	VerbForm=Inf	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
23	virus	_	NOUN	_	Number=Sing	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	HIV	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	_	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	replication	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	"	_	PUNCT	_	_	_	_	_	_
2	Plus	_	CCONJ	_	_	_	_	_	_
3	"	_	PUNCT	_	_	_	_	_	_
4	clones	_	NOUN	_	Number=Plur	_	_	_	_
5	replicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	efficiently	_	ADV	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	whereas	_	SCONJ	_	_	_	_	_	_
11	"	_	PUNCT	_	_	_	_	_	_
12	minus	_	CCONJ	_	_	_	_	_	_
13	"	_	PUNCT	_	_	_	_	_	_
14	clones	_	NOUN	_	Number=Plur	_	_	_	_
15	did	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	clones	_	NOUN	_	Number=Plur	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	differences	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	might	_	AUX	_	VerbForm=Fin	_	_	_	_
19	account	_	VERB	_	VerbForm=Inf	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	plus	_	CCONJ	_	_	_	_	_	_
4	clones	_	NOUN	_	Number=Plur	_	_	_	_
5	liberated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	classical	_	ADJ	_	Degree=Pos	_	_	_	_
8	p50-p65	_	NOUN	_	Number=Sing	_	_	_	_
9	complex	_	NOUN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
12	pools	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	whereas	_	SCONJ	_	_	_	_	_	_
15	minus	_	PRON	_	_	_	_	_	_
16	clones	_	NOUN	_	Number=Plur	_	_	_	_
17	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	apparently	_	ADV	_	_	_	_	_	_
20	novel	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	faster	_	ADJ	_	Degree=Cmp	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	migrating	_	NOUN	_	Number=Sing	_	_	_	_
25	complex	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	as	_	SCONJ	_	_	_	_	_	_
28	judged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
31	mobility	_	NOUN	_	Number=Sing	_	_	_	_
32	shift	_	NOUN	_	Number=Sing	_	_	_	_
33	assays	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	surprising	_	ADJ	_	Degree=Pos	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	faster	_	ADJ	_	Degree=Cmp	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	migrating	_	NOUN	_	Number=Sing	_	_	_	_
9	complex	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	p50	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	p65	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	p65	_	PROPN	_	Number=Sing	_	_	_	_
5	subunit	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	COOH	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	terminally	_	ADV	_	_	_	_	_	_
10	truncated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	as	_	SCONJ	_	_	_	_	_	_
13	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	truncation	_	NOUN	_	Number=Sing	_	_	_	_
3	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	limited	_	ADJ	_	Degree=Pos	_	_	_	_
6	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	p65	_	NOUN	_	Number=Sing	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	extraction	_	NOUN	_	Number=Sing	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	released	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	particular	_	ADJ	_	Degree=Pos	_	_	_	_
15	lysosomal	_	ADJ	_	Number=Sing	_	_	_	_
16	serine	_	NOUN	_	Number=Sing	_	_	_	_
17	proteases	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	such	_	ADJ	_	Degree=Pos	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	elastase	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	cathepsin	_	NOUN	_	Number=Sing	_	_	_	_
24	G	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	proteinase	_	NOUN	_	Number=Sing	_	_	_	_
28	3	_	NUM	_	NumType=Card	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	specific	_	ADJ	_	Degree=Pos	_	_	_	_
3	proteases	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	coordinately	_	ADV	_	_	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	present	_	ADJ	_	Degree=Pos	_	_	_	_
10	exclusively	_	ADV	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	minus	_	NOUN	_	_	_	_	_	_
14	U937	_	NOUN	_	Number=Sing	_	_	_	_
15	clones	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	not	_	ADV	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	plus	_	NOUN	_	Number=Sing	_	_	_	_
22	clones	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	as	_	SCONJ	_	_	_	_	_	_
25	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	case	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	cathepsin	_	NOUN	_	Number=Sing	_	_	_	_
31	G	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	proteases	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	certain	_	ADJ	_	Degree=Pos	_	_	_	_
10	subclones	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	THP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	HL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	60	_	NUM	_	NumType=Card	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	primary	_	ADJ	_	Degree=Pos	_	_	_	_
23	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	each	_	DET	_	_	_	_	_	_
27	case	_	NOUN	_	Number=Sing	_	_	_	_
28	correlating	_	VERB	_	VerbForm=Ger	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	p65	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vitro	_	NOUN	_	Number=Sing	_	_	_	_
5	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	p65	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	elastase	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	cathepsin	_	NOUN	_	Number=Sing	_	_	_	_
13	G	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	possible	_	ADJ	_	Degree=Pos	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	particular	_	ADJ	_	Degree=Pos	_	_	_	_
6	serine	_	NOUN	_	Number=Sing	_	_	_	_
7	proteases	_	NOUN	_	Number=Plur	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	have	_	VERB	_	VerbForm=Inf	_	_	_	_
10	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	effects	_	NOUN	_	Number=Plur	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	replication	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	myelo	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	special	_	ADJ	_	Degree=Pos	_	_	_	_
7	precautions	_	NOUN	_	Number=Plur	_	_	_	_
8	must	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	taken	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	when	_	ADV	_	PronType=Int	_	_	_	_
12	making	_	VERB	_	VerbForm=Ger	_	_	_	_
13	extracts	_	NOUN	_	Number=Plur	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	myelo	_	ADJ	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001217	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	fibroblast	_	NOUN	_	Number=Sing	_	_	_	_
16	conditioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	medium	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
20	PGE2	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	crucially	_	ADV	_	_	_	_	_	_
15	involved	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	several	_	ADJ	_	Degree=Pos	_	_	_	_
22	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	including	_	VERB	_	VerbForm=Ger	_	_	_	_
25	tumor	_	NOUN	_	Number=Sing	_	_	_	_
26	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	TNF	_	PROPN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Previously	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	fibroblast	_	NOUN	_	Number=Sing	_	_	_	_
7	conditioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	medium	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	FCM	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	able	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
16	both	_	CCONJ	_	_	_	_	_	_
17	TNF	_	PROPN	_	Number=Sing	_	_	_	_
18	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
19	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	release	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
25	blood	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	PBM	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	LPS	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	effect	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	FCM	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	LPS	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	DNA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	binding	_	VERB	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	means	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
29	shift	_	NOUN	_	Number=Sing	_	_	_	_
30	assay	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	EMSA	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	evidence	_	NOUN	_	Number=Sing	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	FCM	_	PROPN	_	Number=Sing	_	_	_	_
6	strongly	_	ADV	_	_	_	_	_	_
7	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	LPS	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	PBM	_	PROPN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
7	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
8	mimics	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
14	effect	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	FCM	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	hand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	FCM	_	PROPN	_	Number=Sing	_	_	_	_
7	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	presence	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	indomethacin	_	NOUN	_	Number=Sing	_	_	_	_
13	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	LPS	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	lend	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	further	_	ADJ	_	Degree=Pos	_	_	_	_
5	support	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	immune	_	ADJ	_	Degree=Pos	_	_	_	_
13	responses	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
18	may	_	AUX	_	VerbForm=Fin	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
24	level	_	NOUN	_	Number=Sing	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	signals	_	NOUN	_	Number=Plur	_	_	_	_
27	originating	_	VERB	_	VerbForm=Ger	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	tissue	_	NOUN	_	Number=Sing	_	_	_	_
30	structural	_	ADJ	_	Degree=Pos	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	such	_	ADJ	_	Degree=Pos	_	_	_	_
33	as	_	ADP	_	_	_	_	_	_
34	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001224	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Mitogen	_	PROPN	_	Number=Sing	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	T-cells	_	PROPN	_	Number=Sing	_	_	_	_
5	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	Jun	_	PROPN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	AP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	analysed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
8	lectins	_	NOUN	_	Number=Plur	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	c	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Fos	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	c	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	Jun	_	PROPN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	levels	_	NOUN	_	Number=Plur	_	_	_	_
19	as	_	ADV	_	_	_	_	_	_
20	well	_	ADV	_	Degree=Pos	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	activator	_	NOUN	_	Number=Sing	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	AP	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
35	activity	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
38	T-cells	_	PROPN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	Jun	_	PROPN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	after	_	ADP	_	_	_	_	_	_
12	Con	_	NOUN	_	Number=Sing	_	_	_	_
13	A	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	PHA	_	NOUN	_	Number=Sing	_	_	_	_
16	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	ADP	_	_	_	_	_	_
2	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	both	_	CCONJ	_	_	_	_	_	_
6	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
8	+	_	SYM	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	activates	_	NOUN	_	Number=Plur	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	C	_	PROPN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	PKC	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	possible	_	ADJ	_	Degree=Pos	_	_	_	_
23	involvement	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
27	messengers	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	c	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	Fos	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
34	induction	_	NOUN	_	Number=Sing	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	tested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	PMA	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	which	_	PRON	_	PronType=Rel	_	_	_	_
4	directly	_	ADV	_	_	_	_	_	_
5	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	PKC	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	mimicked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	effect	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	lectins	_	NOUN	_	Number=Plur	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	elevation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	either	_	CCONJ	_	_	_	_	_	_
23	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
24	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
25	+	_	SYM	_	_	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
28	levels	_	NOUN	_	Number=Plur	_	_	_	_
29	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	little	_	ADJ	_	Degree=Pos	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	no	_	DET	_	_	_	_	_	_
33	effect	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	increase	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	c	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Fos	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
12	immunoreactivity	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	H	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	7	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	kinase	_	NOUN	_	Number=Sing	_	_	_	_
22	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	relatively	_	ADV	_	_	_	_	_	_
25	high	_	ADJ	_	Degree=Pos	_	_	_	_
26	specificity	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	PKC	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	less	_	ADV	_	Degree=Cmp	_	_	_	_
32	efficiently	_	ADV	_	_	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	H	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	SYM	_	_	_	_	_	_
36	8	_	NUM	_	NumType=Card	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	structurally	_	ADV	_	_	_	_	_	_
40	related	_	ADJ	_	Degree=Pos	_	_	_	_
41	kinase	_	NOUN	_	Number=Sing	_	_	_	_
42	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
43	less	_	ADV	_	Degree=Cmp	_	_	_	_
44	active	_	ADJ	_	Degree=Pos	_	_	_	_
45	on	_	ADP	_	_	_	_	_	_
46	PKC	_	PROPN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	but	_	CCONJ	_	_	_	_	_	_
49	more	_	ADV	_	_	_	_	_	_
50	active	_	ADJ	_	Degree=Pos	_	_	_	_
51	on	_	ADP	_	_	_	_	_	_
52	cyclic	_	ADJ	_	Degree=Pos	_	_	_	_
53	nucleotide	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
56	kinases	_	NOUN	_	Number=Plur	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Con	_	NOUN	_	Number=Sing	_	_	_	_
2	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
8	both	_	DET	_	_	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	AP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	consensus	_	NOUN	_	Number=Sing	_	_	_	_
20	sequence	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	TRE	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	AP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	PMA	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	AP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	whereas	_	SCONJ	_	_	_	_	_	_
15	elevation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
18	+	_	SYM	_	_	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
21	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	only	_	ADV	_	_	_	_	_	_
23	minor	_	ADJ	_	Degree=Pos	_	_	_	_
24	effects	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
7	lectins	_	NOUN	_	Number=Plur	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	levels	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	AP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	AP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	that	_	SCONJ	_	_	_	_	_	_
34	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
35	act	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	via	_	ADP	_	_	_	_	_	_
37	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
38	that	_	PRON	_	PronType=Rel	_	_	_	_
39	could	_	AUX	_	VerbForm=Fin	_	_	_	_
40	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	activation	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	PKC	_	PROPN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001229	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	myelomonocytic	_	NOUN	_	Degree=Pos	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	line	_	NOUN	_	Number=Sing	_	_	_	_
6	U	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	937	_	NUM	_	NumType=Card	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	model	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	SCONJ	_	_	_	_	_	_
13	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
14	alterations	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	steroid	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	monokine	_	NOUN	_	Number=Sing	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	:	_	PUNCT	_	_	_	_	_	_
23	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	beta	_	NOUN	_	Number=Sing	_	_	_	_
33	messenger	_	NOUN	_	Number=Sing	_	_	_	_
34	RNA	_	PROPN	_	Number=Sing	_	_	_	_
35	levels	_	NOUN	_	Number=Plur	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	1,25	_	NUM	_	NumType=Card	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
40	D3.	_	PROPN	_	Number=Sing	_	_	_	_
41	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	active	_	ADJ	_	Degree=Pos	_	_	_	_
43	metabolite	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
46	D	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	1,25	_	NUM	_	NumType=Card	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
51	D3	_	NOUN	_	Number=Sing	_	_	_	_
52	[	_	PUNCT	_	_	_	_	_	_
53	1,25	_	NUM	_	NumType=Card	_	_	_	_
54	-(	_	PUNCT	_	_	_	_	_	_
55	OH	_	NOUN	_	_	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	2	_	NUM	_	NumType=Card	_	_	_	_
58	D3	_	NOUN	_	Number=Sing	_	_	_	_
59	]	_	PUNCT	_	_	_	_	_	_
60	,	_	PUNCT	_	_	_	_	_	_
61	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
62	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
63	potent	_	ADJ	_	Degree=Pos	_	_	_	_
64	regulator	_	NOUN	_	Number=Sing	_	_	_	_
65	of	_	ADP	_	_	_	_	_	_
66	human	_	ADJ	_	Degree=Pos	_	_	_	_
67	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
68	/	_	PUNCT	_	_	_	_	_	_
69	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
70	function	_	NOUN	_	Number=Sing	_	_	_	_
71	in	_	ADP	_	_	_	_	_	_
72	vitro	_	NOUN	_	Number=Sing	_	_	_	_
73	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	establish	_	VERB	_	VerbForm=Inf	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	model	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	1,25	_	NUM	_	NumType=Card	_	_	_	_
7	-(	_	PUNCT	_	_	_	_	_	_
8	OH	_	NOUN	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	D3	_	NUM	_	NumType=Card	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	monokine	_	NOUN	_	Number=Sing	_	_	_	_
17	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	three	_	NUM	_	NumType=Card	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	lines	_	NOUN	_	Number=Plur	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	U-937	_	NUM	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	THP	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	HL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	60	_	NUM	_	NumType=Card	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	:	_	PUNCT	_	_	_	_	_	_
39	1	_	X	_	_	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	presence	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	functional	_	ADJ	_	Degree=Pos	_	_	_	_
45	1,25	_	NUM	_	NumType=Card	_	_	_	_
46	-(	_	PUNCT	_	_	_	_	_	_
47	OH	_	NOUN	_	_	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	2D3	_	NUM	_	NumType=Card	_	_	_	_
50	receptors	_	NOUN	_	Number=Plur	_	_	_	_
51	;	_	PUNCT	_	_	_	_	_	_
52	2	_	X	_	_	_	_	_	_
53	)	_	PUNCT	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	1	_	NUM	_	NumType=Card	_	_	_	_
60	beta	_	NOUN	_	Number=Sing	_	_	_	_
61	(	_	PUNCT	_	_	_	_	_	_
62	IL	_	PROPN	_	Number=Sing	_	_	_	_
63	-	_	PUNCT	_	_	_	_	_	_
64	1	_	NUM	_	NumType=Card	_	_	_	_
65	beta	_	NOUN	_	Number=Sing	_	_	_	_
66	)	_	PUNCT	_	_	_	_	_	_
67	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
68	and	_	CCONJ	_	_	_	_	_	_
69	IL	_	PROPN	_	Number=Sing	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	1	_	NUM	_	NumType=Card	_	_	_	_
72	beta	_	NOUN	_	Number=Sing	_	_	_	_
73	protein	_	NOUN	_	Number=Sing	_	_	_	_
74	in	_	ADP	_	_	_	_	_	_
75	response	_	NOUN	_	Number=Sing	_	_	_	_
76	to	_	ADP	_	_	_	_	_	_
77	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
78	(	_	PUNCT	_	_	_	_	_	_
79	LPS	_	NOUN	_	Number=Sing	_	_	_	_
80	)	_	PUNCT	_	_	_	_	_	_
81	;	_	PUNCT	_	_	_	_	_	_
82	and	_	CCONJ	_	_	_	_	_	_
83	3	_	X	_	_	_	_	_	_
84	)	_	PUNCT	_	_	_	_	_	_
85	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
86	regulation	_	NOUN	_	Number=Sing	_	_	_	_
87	of	_	ADP	_	_	_	_	_	_
88	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
89	response	_	NOUN	_	Number=Sing	_	_	_	_
90	by	_	ADP	_	_	_	_	_	_
91	1,25	_	NUM	_	NumType=Card	_	_	_	_
92	-(	_	PUNCT	_	_	_	_	_	_
93	OH	_	NOUN	_	_	_	_	_	_
94	)	_	PUNCT	_	_	_	_	_	_
95	2	_	NUM	_	NumType=Card	_	_	_	_
96	D3	_	NOUN	_	Number=Sing	_	_	_	_
97	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	three	_	NUM	_	NumType=Card	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
7	D	_	PROPN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	beta	_	NOUN	_	Number=Sing	_	_	_	_
18	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	response	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	LPS	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Preincubation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	1,25	_	NUM	_	NumType=Card	_	_	_	_
6	-(	_	PUNCT	_	_	_	_	_	_
7	OH	_	NOUN	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	2D3	_	PROPN	_	Number=Sing	_	_	_	_
10	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
16	levels	_	NOUN	_	Number=Plur	_	_	_	_
17	only	_	ADV	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	U	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	937	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	HL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	60	_	NUM	_	NumType=Card	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	From	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	data	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	taking	_	VERB	_	VerbForm=Ger	_	_	_	_
7	into	_	ADP	_	_	_	_	_	_
8	consideration	_	NOUN	_	Number=Sing	_	_	_	_
9	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	state	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	relative	_	ADJ	_	Degree=Pos	_	_	_	_
15	ease	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	culture	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	U	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	937	_	NUM	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	chosen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	over	_	ADP	_	_	_	_	_	_
25	HL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	60	_	NUM	_	NumType=Card	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	THP	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	line	_	NOUN	_	Number=Sing	_	_	_	_
36	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
37	further	_	ADV	_	_	_	_	_	_
38	characterized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	U-937	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	optimum	_	ADJ	_	Degree=Pos	_	_	_	_
6	time	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	dose	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	1,25	_	NUM	_	NumType=Card	_	_	_	_
13	-(	_	PUNCT	_	_	_	_	_	_
14	OH	_	INTJ	_	_	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	D3	_	NOUN	_	Number=Sing	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	determined	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	12	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	24	_	NUM	_	NumType=Card	_	_	_	_
25	h	_	NOUN	_	Number=Plur	_	_	_	_
26	at	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	receptor	_	NOUN	_	Number=Sing	_	_	_	_
29	saturating	_	NOUN	_	Number=Sing	_	_	_	_
30	concentration	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	1,25	_	NUM	_	NumType=Card	_	_	_	_
33	-(	_	PUNCT	_	_	_	_	_	_
34	OH	_	NOUN	_	_	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	2D3	_	NUM	_	NumType=Card	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	10	_	NUM	_	NumType=Card	_	_	_	_
39	nM	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Preincubation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	1,25	_	NUM	_	NumType=Card	_	_	_	_
6	-(	_	PUNCT	_	_	_	_	_	_
7	OH	_	INTJ	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	2D3	_	NUM	_	Number=Sing	_	_	_	_
10	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	no	_	DET	_	_	_	_	_	_
12	effect	_	NOUN	_	Number=Sing	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	time	_	NOUN	_	Number=Sing	_	_	_	_
16	course	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	beta	_	NOUN	_	Number=Sing	_	_	_	_
22	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
23	appearance	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	response	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	LPS	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	exposure	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	U	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	SYM	_	_	_	_	_	_
7	937	_	NUM	_	NumType=Card	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	1,25	_	NUM	_	NumType=Card	_	_	_	_
11	-(	_	PUNCT	_	_	_	_	_	_
12	OH	_	INTJ	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	2D3	_	NUM	_	NumType=Card	_	_	_	_
15	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	200	_	NUM	_	NumType=Card	_	_	_	_
18	%	_	SYM	_	Number=Sing	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	beta	_	NOUN	_	Number=Sing	_	_	_	_
26	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
27	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	three	_	NUM	_	NumType=Card	_	_	_	_
32	orders	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	concentration	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	LPS	_	NOUN	_	Number=Sing	_	_	_	_
39	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	to	_	PART	_	_	_	_	_	_
41	achieve	_	VERB	_	VerbForm=Inf	_	_	_	_
42	steady	_	ADJ	_	Degree=Pos	_	_	_	_
43	state	_	NOUN	_	Number=Sing	_	_	_	_
44	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
45	levels	_	NOUN	_	Number=Plur	_	_	_	_
46	equivalent	_	ADJ	_	Degree=Pos	_	_	_	_
47	to	_	ADP	_	_	_	_	_	_
48	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
49	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	U	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	937	_	NUM	_	NumType=Card	_	_	_	_
54	cells	_	NOUN	_	Number=Plur	_	_	_	_
55	not	_	ADV	_	_	_	_	_	_
56	preincubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
57	with	_	ADP	_	_	_	_	_	_
58	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
59	hormone	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_
61	2+o	_	NUM	_	NumType=Card	_	_	_	_
62	Document	_	NOUN	_	Number=Sing	_	_	_	_
63	003001230	_	NUM	_	NumType=Card	_	_	_	_
64	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	potentiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	antiviral	_	ADJ	_	Degree=Pos	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	interferon	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	stimulated	_	VERB	_	Degree=Pos	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	interferon	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	U937	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	type	_	NOUN	_	Number=Sing	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	interferon	_	VERB	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	receptors	_	NOUN	_	Number=Plur	_	_	_	_
16	results	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	independent	_	ADJ	_	Degree=Pos	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	IFN	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	stimulated	_	VERB	_	Degree=Pos	_	_	_	_
34	genes	_	NOUN	_	Number=Plur	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	ISGs	_	NOUN	_	Number=Plur	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	human	_	ADJ	_	Degree=Pos	_	_	_	_
40	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	Daudi	_	PROPN	_	Number=Sing	_	_	_	_
45	cell	_	NOUN	_	Number=Sing	_	_	_	_
46	lines	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	ISGF3	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	conserved	_	ADJ	_	Degree=Pos	_	_	_	_
16	IFN	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	element	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	ISRE	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	results	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	DNA	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	ISGF3	_	NOUN	_	Number=Sing	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	normally	_	ADV	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	present	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	other	_	ADJ	_	Degree=Pos	_	_	_	_
26	IFN	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	proteins	_	NOUN	_	Number=Plur	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	preexist	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	as	_	ADP	_	_	_	_	_	_
35	latent	_	ADJ	_	Degree=Pos	_	_	_	_
36	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
37	precursors	_	NOUN	_	Number=Plur	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	ISGF3	_	PROPN	_	Number=Sing	_	_	_	_
40	alpha	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	ISG	_	PROPN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
10	U937	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	line	_	NOUN	_	Number=Sing	_	_	_	_
13	differs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	most	_	ADJ	_	Degree=Sup	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	lines	_	NOUN	_	Number=Plur	_	_	_	_
18	previously	_	ADV	_	_	_	_	_	_
19	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	U937	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	both	_	DET	_	_	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	II	_	NUM	_	NumType=Card	_	_	_	_
10	IFN	_	PROPN	_	Number=Sing	_	_	_	_
11	receptors	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	only	_	ADV	_	_	_	_	_	_
15	IFN	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	capable	_	ADJ	_	Degree=Pos	_	_	_	_
20	of	_	SCONJ	_	_	_	_	_	_
21	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	antiviral	_	ADJ	_	Degree=Pos	_	_	_	_
23	protection	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	IFN	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	gamma	_	NOUN	_	Number=Sing	_	_	_	_
6	potentiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IFN	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	protection	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	IFN	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	gamma	_	NOUN	_	Number=Sing	_	_	_	_
19	alone	_	ADV	_	_	_	_	_	_
20	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	have	_	VERB	_	VerbForm=Inf	_	_	_	_
23	any	_	DET	_	_	_	_	_	_
24	antiviral	_	ADJ	_	Degree=Pos	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	ISG15	_	PROPN	_	Number=Sing	_	_	_	_
2	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
3	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	U937	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
10	before	_	ADP	_	_	_	_	_	_
11	6	_	NUM	_	NumType=Card	_	_	_	_
12	h	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	IFN	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	treatment	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	peaks	_	NOUN	_	Number=Plur	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	24	_	NUM	_	NumType=Card	_	_	_	_
22	h	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	IFN	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	gamma	_	NOUN	_	Number=Sing	_	_	_	_
5	alone	_	ADV	_	_	_	_	_	_
6	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
9	ISG	_	PROPN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	IFN	_	ADJ	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	gamma	_	NOUN	_	Number=Sing	_	_	_	_
15	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
16	markedly	_	ADV	_	_	_	_	_	_
17	increases	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	hastens	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	ISG	_	PROPN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
24	induction	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	extracts	_	NOUN	_	Number=Plur	_	_	_	_
3	assayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	presence	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	ISRE	_	PROPN	_	Number=Sing	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
13	mobility	_	NOUN	_	Number=Sing	_	_	_	_
14	shift	_	NOUN	_	Number=Sing	_	_	_	_
15	assays	_	NOUN	_	Number=Plur	_	_	_	_
16	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	ISGF3	_	PROPN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	IFN	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	within	_	ADP	_	_	_	_	_	_
26	6	_	NUM	_	NumType=Card	_	_	_	_
27	h	_	NOUN	_	Number=Sing	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	undetectable	_	ADJ	_	Degree=Pos	_	_	_	_
30	basal	_	ADJ	_	Degree=Pos	_	_	_	_
31	levels	_	NOUN	_	Number=Plur	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
34	U937	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	ISGF3	_	PROPN	_	Number=Sing	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	latent	_	ADJ	_	Degree=Pos	_	_	_	_
8	component	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	ISGF3	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	rapidly	_	ADV	_	_	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	increase	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	ISGF3	_	PROPN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	ultimately	_	ADV	_	_	_	_	_	_
9	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	ISGF3	_	NOUN	_	Number=Sing	_	_	_	_
15	gamma	_	NOUN	_	Number=Sing	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	IFN	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	IFN	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	gamma	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	003001242	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Clone	_	PROPN	_	Number=Sing	_	_	_	_
2	pAT	_	PROPN	_	Number=Sing	_	_	_	_
3	133	_	NUM	_	NumType=Card	_	_	_	_
4	identifies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	another	_	DET	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	member	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	class	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	growth	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	almost	_	ADV	_	_	_	_	_	_
23	identical	_	ADJ	_	Degree=Pos	_	_	_	_
24	zinc	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	finger	_	NOUN	_	Number=Sing	_	_	_	_
27	domains	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	structure	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	represented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	clone	_	NOUN	_	Number=Sing	_	_	_	_
13	pAT	_	NOUN	_	Number=Sing	_	_	_	_
14	133	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	upon	_	ADP	_	_	_	_	_	_
20	transition	_	NOUN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	resting	_	NOUN	_	VerbForm=Ger	_	_	_	_
24	state	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	G0	_	X	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	through	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	early	_	ADJ	_	Degree=Pos	_	_	_	_
31	phase	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	cycle	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	G1	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	pAT	_	NOUN	_	Number=Sing	_	_	_	_
3	133	_	NUM	_	NumType=Card	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	immediately	_	ADV	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	FOS	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	like	_	ADP	_	Degree=Pos	_	_	_	_
13	kinetics	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Primary	_	ADJ	_	Degree=Pos	_	_	_	_
2	structure	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	three	_	NUM	_	NumType=Card	_	_	_	_
11	tandem	_	NOUN	_	Number=Sing	_	_	_	_
12	zinc	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	finger	_	NOUN	_	Number=Sing	_	_	_	_
15	sequences	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	Cys2-Xaa12	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	His2	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	zinc	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	finger	_	NOUN	_	Number=Sing	_	_	_	_
5	region	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	sequence	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	manner	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	similar	_	ADJ	_	Degree=Pos	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
24	than	_	ADP	_	_	_	_	_	_
25	80	_	NUM	_	NumType=Card	_	_	_	_
26	%	_	SYM	_	Number=Sing	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	amino	_	ADJ	_	Number=Sing	_	_	_	_
30	acid	_	NOUN	_	Number=Sing	_	_	_	_
31	level	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	two	_	NUM	_	NumType=Card	_	_	_	_
35	previously	_	ADV	_	_	_	_	_	_
36	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	factors	_	NOUN	_	Number=Plur	_	_	_	_
39	pAT	_	PROPN	_	Number=Sing	_	_	_	_
40	225	_	NUM	_	NumType=Card	_	_	_	_
41	/	_	PUNCT	_	_	_	_	_	_
42	EGR1	_	PROPN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	pAT	_	NOUN	_	Number=Sing	_	_	_	_
45	591	_	NUM	_	NumType=Card	_	_	_	_
46	/	_	PUNCT	_	_	_	_	_	_
47	EGR2	_	PROPN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Except	_	ADP	_	_	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	conserved	_	VERB	_	Degree=Pos	_	_	_	_
5	zinc	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	finger	_	NOUN	_	Number=Sing	_	_	_	_
8	domains	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	amino	_	NOUN	_	Degree=Pos	_	_	_	_
12	acid	_	VERB	_	Number=Sing	_	_	_	_
13	sequences	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	three	_	NUM	_	NumType=Card	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	structural	_	ADJ	_	Degree=Pos	_	_	_	_
3	similarity	_	NOUN	_	Number=Sing	_	_	_	_
4	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	pAT	_	NOUN	_	Number=Sing	_	_	_	_
8	133	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	biological	_	ADJ	_	Degree=Pos	_	_	_	_
18	function	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Comparing	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	regulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	related	_	ADJ	_	Degree=Pos	_	_	_	_
7	zinc	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	finger	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	encoding	_	VERB	_	Number=Sing	_	_	_	_
12	genes	_	NOUN	_	Number=Plur	_	_	_	_
13	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	coordinate	_	ADJ	_	Degree=Pos	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	upon	_	ADP	_	_	_	_	_	_
17	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
18	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	SCONJ	_	_	_	_	_	_
20	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	of	_	SCONJ	_	_	_	_	_	_
25	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	upon	_	ADP	_	_	_	_	_	_
4	transition	_	NOUN	_	Number=Sing	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	proliferating	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	G1	_	X	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
14	state	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	cycle	_	NOUN	_	Number=Sing	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	three	_	NUM	_	NumType=Card	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	differently	_	ADV	_	_	_	_	_	_
24	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	histiocytic	_	ADJ	_	Degree=Pos	_	_	_	_
4	U937	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	clone	_	NOUN	_	Number=Sing	_	_	_	_
9	pAT	_	PROPN	_	Number=Sing	_	_	_	_
10	133	_	NUM	_	NumType=Card	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	constitutively	_	ADV	_	_	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	whereas	_	SCONJ	_	_	_	_	_	_
16	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	pAT	_	PROPN	_	Number=Sing	_	_	_	_
19	225	_	NUM	_	NumType=Card	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	EGR1	_	PROPN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	upon	_	ADP	_	_	_	_	_	_
25	induction	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
28	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
4	representing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	pAT	_	NOUN	_	Number=Sing	_	_	_	_
6	591	_	NUM	_	NumType=Card	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	EGR2	_	PROPN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	difference	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
8	biological	_	ADJ	_	Degree=Pos	_	_	_	_
9	roles	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	control	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	respective	_	ADJ	_	Degree=Pos	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001243	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	PROPN	_	Number=Sing	_	_	_	_
4	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
6	STAT	_	NOUN	_	Number=Sing	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	upregulates	_	VERB	_	Number=Plur	_	_	_	_
10	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2Ralpha	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	c-myc	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	pim	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	pleiotropic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	antiviral	_	ADJ	_	Degree=Pos	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	antiproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	immunoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	functions	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	evidence	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	PROPN	_	Number=Sing	_	_	_	_
9	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	important	_	ADJ	_	Degree=Pos	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
15	biology	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	c-myc	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	pim	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	anti-CD3	_	ADJ	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	genes	_	NOUN	_	Number=Plur	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
20	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	12	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	15	_	NUM	_	NumType=Card	_	_	_	_
22	upregulated	_	VERB	_	Degree=Pos	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	c-myc	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	pim	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	IFN	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	sensitized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	further	_	ADV	_	_	_	_	_	_
17	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	IFN	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	may	_	AUX	_	VerbForm=Fin	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	involved	_	ADJ	_	Degree=Pos	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	regulation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
30	mitogenesis	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	nature	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	STAT	_	PROPN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	capable	_	ADJ	_	Degree=Pos	_	_	_	_
10	of	_	SCONJ	_	_	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	pim	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	IRF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	GAS	_	NOUN	_	Number=Sing	_	_	_	_
26	elements	_	NOUN	_	Number=Plur	_	_	_	_
27	after	_	ADP	_	_	_	_	_	_
28	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
29	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
32	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	IFN	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	alpha	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	binding	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	STAT4	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	but	_	CCONJ	_	_	_	_	_	_
48	not	_	ADV	_	_	_	_	_	_
49	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	all	_	DET	_	_	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
54	elements	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Yet	_	CCONJ	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IFN	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	alpha	_	PROPN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	able	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	high	_	ADJ	_	Degree=Pos	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	affinity	_	NOUN	_	Number=Sing	_	_	_	_
18	IFP53	_	PROPN	_	Number=Sing	_	_	_	_
19	GAS	_	NOUN	_	Number=Sing	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	IFN	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	STAT4	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	STAT5a	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	STAT5b	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	12	_	NUM	_	NumType=Card	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	STAT4	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	15	_	NUM	_	NumType=Card	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	GAS	_	NOUN	_	Number=Sing	_	_	_	_
20	elements	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	IFN	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	12	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	15	_	NUM	_	NumType=Card	_	_	_	_
24	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	overlapping	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	activities	_	NOUN	_	Number=Plur	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	T	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	thus	_	ADV	_	_	_	_	_	_
4	emphasize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	importance	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IFN	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001246	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	alternatively	_	ADV	_	_	_	_	_	_
3	spliced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	isoform	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Spi-B	_	ADJ	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Spi-B	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	Ets	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	related	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	oncoprotein	_	NOUN	_	Degree=Pos	_	_	_	_
11	Spi-1	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	highly	_	ADV	_	_	_	_	_	_
16	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	B	_	ADJ	_	Number=Sing	_	_	_	_
19	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Ets	_	NOUN	_	Number=Sing	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	share	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	Ets	_	NOUN	_	Number=Sing	_	_	_	_
8	domain	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Spi-B	_	ADJ	_	Number=Sing	_	_	_	_
2	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	sequences	_	NOUN	_	Number=Plur	_	_	_	_
5	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	core	_	NOUN	_	Number=Sing	_	_	_	_
8	5'-	_	NUM	_	Number=Sing	_	_	_	_
9	GGAA	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	SYM	_	_	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	'	_	NOUN	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
18	motif	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Up	_	ADP	_	_	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	date	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	biological	_	ADJ	_	Degree=Pos	_	_	_	_
7	function	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Spi-B	_	PROPN	_	Number=Sing	_	_	_	_
10	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	characterization	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	alternatively	_	ADV	_	_	_	_	_	_
10	spliced	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
11	variant	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Spi-B	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	named	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	deltaSpi	_	PROPN	_	Number=Sing	_	_	_	_
17	-B	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	lost	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	Ets	_	NOUN	_	Number=Sing	_	_	_	_
24	domain	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	B	_	ADJ	_	Number=Sing	_	_	_	_
3	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	deltaspi	_	NOUN	_	Number=Sing	_	_	_	_
7	-B	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	spi	_	NOUN	_	Number=Sing	_	_	_	_
10	-B	_	PUNCT	_	Number=Sing	_	_	_	_
11	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	present	_	ADJ	_	Degree=Pos	_	_	_	_
14	simultaneously	_	ADV	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	ratio	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	around	_	ADV	_	_	_	_	_	_
20	10	_	NUM	_	NumType=Card	_	_	_	_
21	%	_	SYM	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	DeltaSpi	_	NOUN	_	Number=Sing	_	_	_	_
2	-B	_	NOUN	_	Number=Sing	_	_	_	_
3	product	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	ADV	_	_	_	_	_	_
6	able	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
9	DNA	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	recovered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
15	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
16	extracts	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	raise	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	SCONJ	_	PronType=Rel	_	_	_	_
6	delta	_	PROPN	_	Number=Sing	_	_	_	_
7	Spi	_	PROPN	_	Number=Sing	_	_	_	_
8	-B	_	PUNCT	_	Number=Sing	_	_	_	_
9	might	_	AUX	_	VerbForm=Fin	_	_	_	_
10	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
11	Spi	_	NOUN	_	Number=Sing	_	_	_	_
12	-B	_	NOUN	_	Number=Sing	_	_	_	_
13	function	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	recruiting	_	NOUN	_	Number=Sing	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	involved	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	Spi-B	_	ADJ	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001250	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	ZAP	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	70	_	NUM	_	NumType=Card	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	CD45	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	involvement	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	UV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	signal	_	NOUN	_	Number=Sing	_	_	_	_
24	transduction	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
3	responses	_	NOUN	_	Number=Plur	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	UV	_	PROPN	_	Number=Sing	_	_	_	_
6	irradiation	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	including	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
21	tyrosine	_	ADJ	_	Number=Sing	_	_	_	_
22	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	UV	_	PROPN	_	Number=Sing	_	_	_	_
2	irradiation	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	H2O2	_	ADJ	_	Number=Sing	_	_	_	_
5	treatment	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
12	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
15	+	_	SYM	_	_	_	_	_	_
16	signals	_	NOUN	_	Number=Plur	_	_	_	_
17	similar	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
20	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	following	_	VERB	_	VerbForm=Ger	_	_	_	_
22	biological	_	ADJ	_	Degree=Pos	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	surface	_	NOUN	_	Number=Sing	_	_	_	_
9	molecules	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	responses	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Normal	_	ADJ	_	Degree=Pos	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
5	surface	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	CD3	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	depleted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	showed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
13	UV	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
17	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_
21	signals	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Similarly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
4	T	_	NOUN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	lines	_	NOUN	_	Number=Plur	_	_	_	_
7	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	CD3	_	PROPN	_	Number=Sing	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	CD45	_	PROPN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	gave	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	impaired	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
16	UV	_	PROPN	_	Number=Sing	_	_	_	_
17	responses	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	all	_	DET	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	types	_	NOUN	_	Number=Plur	_	_	_	_
7	still	_	ADV	_	_	_	_	_	_
8	gave	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	strong	_	ADJ	_	Degree=Pos	_	_	_	_
10	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
11	+	_	SYM	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	tyrosine	_	ADJ	_	Number=Sing	_	_	_	_
14	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
15	responses	_	NOUN	_	Number=Plur	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	ZAP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	70	_	NUM	_	NumType=Card	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	highly	_	ADV	_	_	_	_	_	_
14	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	UV	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	H2O2	_	ADJ	_	Number=Sing	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	ZAP	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	70	_	NUM	_	NumType=Card	_	_	_	_
4	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	UV	_	PROPN	_	Number=Sing	_	_	_	_
7	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	CD3	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	CD45	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	whereas	_	SCONJ	_	_	_	_	_	_
16	only	_	ADV	_	_	_	_	_	_
17	CD3	_	PROPN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	UV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	CD3	_	PROPN	_	Number=Sing	_	_	_	_
14	depletion	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	importance	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	such	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	surface	_	NOUN	_	Number=Sing	_	_	_	_
23	molecules	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	biological	_	ADJ	_	Degree=Pos	_	_	_	_
26	responses	_	NOUN	_	Number=Plur	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	UV	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	nonlymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	epidermal	_	ADJ	_	Degree=Pos	_	_	_	_
7	growth	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	displayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
13	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
14	within	_	ADP	_	_	_	_	_	_
15	seconds	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	UV	_	PROPN	_	Number=Sing	_	_	_	_
18	irradiation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	UV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	signal	_	NOUN	_	Number=Sing	_	_	_	_
9	transduction	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	via	_	ADP	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	surface	_	NOUN	_	Number=Sing	_	_	_	_
15	receptors	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	normally	_	ADV	_	_	_	_	_	_
18	respond	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	biological	_	ADJ	_	Degree=Pos	_	_	_	_
21	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	whereas	_	SCONJ	_	_	_	_	_	_
24	H2O2	_	PROPN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	able	_	ADJ	_	Degree=Pos	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	partially	_	ADV	_	_	_	_	_	_
29	bypass	_	VERB	_	VerbForm=Inf	_	_	_	_
30	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	requirement	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001256	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
6	bufalin	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
10	through	_	ADP	_	_	_	_	_	_
11	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	mitogen	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
22	U937	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	previous	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	bufalin	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	active	_	ADJ	_	Degree=Pos	_	_	_	_
15	principle	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Chinese	_	ADJ	_	Degree=Pos	_	_	_	_
18	medicine	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	chan	_	PROPN	_	Number=Sing	_	_	_	_
21	'su	_	NOUN	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
28	U937	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	anomalous	_	ADJ	_	Degree=Pos	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	protein	_	NOUN	_	Number=Sing	_	_	_	_
38	kinase	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	via	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
45	pathway	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	Ras	_	PROPN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	Raf	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	1	_	NUM	_	NumType=Card	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	and	_	CCONJ	_	_	_	_	_	_
54	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
55	kinase	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	1	_	NUM	_	NumType=Card	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	bcl	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	U937	_	NUM	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
19	pathway	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	bufalin	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	bufalin	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	U937	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	significantly	_	ADV	_	_	_	_	_	_
15	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	significant	_	ADJ	_	Degree=Pos	_	_	_	_
3	difference	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	bufalin	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	wild	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	Bcl-2	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
27	U937	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	;	_	PUNCT	_	_	_	_	_	_
30	however	_	ADV	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	bufalin	_	NOUN	_	Number=Sing	_	_	_	_
38	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
39	significantly	_	ADV	_	_	_	_	_	_
40	attenuated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	overexpressing	_	VERB	_	VerbForm=Ger	_	_	_	_
45	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	2	_	NUM	_	NumType=Card	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Bufalin	_	ADJ	_	Degree=Pos	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	activator	_	NOUN	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	;	_	PUNCT	_	_	_	_	_	_
11	however	_	ADV	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	40	_	NUM	_	NumType=Card	_	_	_	_
19	%	_	SYM	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	bcl	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
26	U937	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	acts	_	NOUN	_	Number=Plur	_	_	_	_
9	downstream	_	ADV	_	Degree=Pos	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	upstream	_	ADV	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
26	pathway	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
30	process	_	NOUN	_	Number=Sing	_	_	_	_
31	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	bufalin	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
37	activity	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	activator	_	NOUN	_	Number=Sing	_	_	_	_
40	protein	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	may	_	AUX	_	VerbForm=Fin	_	_	_	_
44	be	_	AUX	_	VerbForm=Inf	_	_	_	_
45	down	_	ADV	_	_	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	through	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
53	activity	_	NOUN	_	Number=Sing	_	_	_	_
54	by	_	ADP	_	_	_	_	_	_
55	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	2	_	NUM	_	NumType=Card	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001257	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	Mycobacterium	_	PROPN	_	Number=Sing	_	_	_	_
8	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Soluble	_	ADJ	_	Number=Sing	_	_	_	_
2	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	sera	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	patients	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	advanced	_	ADJ	_	Degree=Pos	_	_	_	_
27	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	levels	_	NOUN	_	Number=Plur	_	_	_	_
31	decline	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	after	_	ADP	_	_	_	_	_	_
33	therapy	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	accordance	_	NOUN	_	Number=Sing	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	improvement	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	radiologic	_	ADJ	_	Degree=Pos	_	_	_	_
40	findings	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2Ralpha	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	bronchoalveolar	_	NOUN	_	Number=Sing	_	_	_	_
11	lavage	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	BAL	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	active	_	ADJ	_	Degree=Pos	_	_	_	_
18	pulmonary	_	ADJ	_	Degree=Pos	_	_	_	_
19	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	evaluated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
25	Mycobacterium	_	PROPN	_	Number=Sing	_	_	_	_
26	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
27	induces	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
34	using	_	VERB	_	VerbForm=Ger	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	THP	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
40	phagocyte	_	NOUN	_	Number=Sing	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	line	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	BAL	_	ADJ	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	involved	_	ADJ	_	Degree=Pos	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	active	_	ADJ	_	Degree=Pos	_	_	_	_
19	pulmonary	_	ADJ	_	Degree=Pos	_	_	_	_
20	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	chain	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2Ralpha	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
13	blood	_	NOUN	_	Number=Sing	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	PBM	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	M.	_	PROPN	_	Number=Sing	_	_	_	_
22	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	flow	_	NOUN	_	Number=Sing	_	_	_	_
25	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
26	evaluation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	after	_	ADP	_	_	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	M.	_	PROPN	_	Number=Sing	_	_	_	_
15	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	further	_	ADV	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	interferon	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	gamma	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	IFN	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	gamma	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	site	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	transcriptionally	_	ADV	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	M.	_	PROPN	_	Number=Sing	_	_	_	_
23	tuberculosis	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
29	site	_	NOUN	_	Number=Sing	_	_	_	_
30	could	_	AUX	_	VerbForm=Fin	_	_	_	_
31	confer	_	VERB	_	VerbForm=Inf	_	_	_	_
32	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
36	herpes	_	NOUN	_	Number=Sing	_	_	_	_
37	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
38	kinase	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	TK	_	PROPN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	M.	_	PROPN	_	Number=Sing	_	_	_	_
45	tuberculosis	_	PROPN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EMSAs	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	upon	_	ADP	_	_	_	_	_	_
21	induction	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	M.	_	PROPN	_	Number=Sing	_	_	_	_
24	tuberculosis	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
3	against	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	p50	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	p65	_	NUM	_	Number=Sing	_	_	_	_
8	subunits	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	EMSAs	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	involvement	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	p50	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	p65	_	NOUN	_	Number=Sing	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	further	_	ADV	_	_	_	_	_	_
26	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	Ralpha	_	PROPN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	M.	_	PROPN	_	Number=Sing	_	_	_	_
14	tuberculosis	_	PROPN	_	Number=Sing	_	_	_	_
15	infection	_	NOUN	_	Number=Sing	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	play	_	VERB	_	VerbForm=Inf	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	important	_	ADJ	_	Degree=Pos	_	_	_	_
20	immunomodulatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	host	_	NOUN	_	Number=Sing	_	_	_	_
25	response	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001258	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	beta	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	globin	_	NOUN	_	Number=Sing	_	_	_	_
7	locus	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	beta-globin	_	NOUN	_	Degree=Pos	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	cluster	_	NOUN	_	Number=Sing	_	_	_	_
8	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	upon	_	ADP	_	_	_	_	_	_
10	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	sequences	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	collectively	_	ADV	_	_	_	_	_	_
17	termed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	locus	_	NOUN	_	Number=Sing	_	_	_	_
20	control	_	NOUN	_	Number=Sing	_	_	_	_
21	region	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	provided	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	new	_	ADJ	_	Degree=Pos	_	_	_	_
6	insights	_	NOUN	_	Number=Plur	_	_	_	_
7	into	_	SCONJ	_	_	_	_	_	_
8	how	_	ADV	_	PronType=Int	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	individual	_	ADJ	_	Degree=Pos	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	cluster	_	NOUN	_	Number=Sing	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	through	_	ADP	_	_	_	_	_	_
18	development	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	crux	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	how	_	ADV	_	PronType=Int	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	locus	_	NOUN	_	Number=Sing	_	_	_	_
10	control	_	NOUN	_	Number=Sing	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	communicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
18	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	elements	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001268	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	KB	_	PROPN	_	Number=Sing	_	_	_	_
6	during	_	ADP	_	_	_	_	_	_
7	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
8	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	type	_	NOUN	_	Number=Sing	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	infection	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	production	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	progeny	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	followed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	U937	_	NOUN	_	Number=Sing	_	_	_	_
20	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	line	_	NOUN	_	Number=Sing	_	_	_	_
23	after	_	ADP	_	_	_	_	_	_
24	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
25	either	_	ADV	_	_	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
28	acid	_	NOUN	_	Number=Sing	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	PMA	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	purified	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
35	human	_	ADJ	_	Degree=Pos	_	_	_	_
36	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	Southwestern	_	ADJ	_	Degree=Pos	_	_	_	_
7	blotting	_	NOUN	_	Number=Sing	_	_	_	_
8	experiments	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	detect	_	VERB	_	VerbForm=Inf	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
17	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	KB	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	double	_	ADJ	_	Degree=Pos	_	_	_	_
25	repeat	_	VERB	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	KB	_	PROPN	_	Number=Sing	_	_	_	_
28	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
29	sequence	_	NOUN	_	Number=Sing	_	_	_	_
30	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	long	_	ADJ	_	Degree=Pos	_	_	_	_
34	terminal	_	NOUN	_	Number=Sing	_	_	_	_
35	repeat	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	PMA	_	NOUN	_	Number=Sing	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	not	_	ADV	_	_	_	_	_	_
6	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
7	acid	_	ADJ	_	Number=Sing	_	_	_	_
8	treatment	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	U937	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	in	_	SCONJ	_	_	_	_	_	_
15	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	KB	_	PROPN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	extracts	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	KB	_	PROPN	_	Number=Sing	_	_	_	_
14	occurred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	only	_	ADV	_	_	_	_	_	_
16	if	_	SCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	previously	_	ADV	_	_	_	_	_	_
21	infected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	HIV	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	U937	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	infected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	no	_	DET	_	_	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	KB	_	PROPN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whereas	_	ADV	_	_	_	_	_	_
22	high	_	ADJ	_	Degree=Pos	_	_	_	_
23	level	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	progeny	_	NOUN	_	Number=Sing	_	_	_	_
26	virions	_	NOUN	_	Number=Plur	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
35	not	_	PART	_	_	_	_	_	_
36	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	viral	_	ADJ	_	Degree=Pos	_	_	_	_
39	replication	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lineage	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	HIV	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	could	_	AUX	_	VerbForm=Fin	_	_	_	_
14	mimic	_	VERB	_	VerbForm=Inf	_	_	_	_
15	some	_	DET	_	_	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
20	allowing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	KB	_	PROPN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001281	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	during	_	ADP	_	_	_	_	_	_
4	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
7	maturation	_	NOUN	_	Number=Sing	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
12	molecules	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
9	donors	_	NOUN	_	Number=Plur	_	_	_	_
10	show	_	VERB	_	VerbForm=Inf	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	time	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	into	_	ADP	_	_	_	_	_	_
17	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
18	upon	_	ADP	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	vitro	_	ADJ	_	Degree=Pos	_	_	_	_
21	cultivation	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	closely	_	ADV	_	_	_	_	_	_
24	mimicking	_	VERB	_	VerbForm=Ger	_	_	_	_
25	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	vivo	_	NOUN	_	Degree=Pos	_	_	_	_
28	migration	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	maturation	_	NOUN	_	Number=Sing	_	_	_	_
31	into	_	ADP	_	_	_	_	_	_
32	extravascular	_	ADJ	_	Degree=Pos	_	_	_	_
33	tissues	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mediator	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	s	_	X	_	_	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	maturation	_	NOUN	_	Number=Sing	_	_	_	_
9	process	_	NOUN	_	Number=Sing	_	_	_	_
10	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	yet	_	ADV	_	_	_	_	_	_
14	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	involvement	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	signal	_	NOUN	_	Number=Sing	_	_	_	_
7	transducers	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	activators	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	STAT	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
18	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	time	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	starting	_	VERB	_	VerbForm=Ger	_	_	_	_
33	at	_	ADP	_	_	_	_	_	_
34	day	_	NOUN	_	Number=Sing	_	_	_	_
35	0/1	_	NUM	_	NumType=Card	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	cultivation	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	maximally	_	ADV	_	_	_	_	_	_
40	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	at	_	ADP	_	_	_	_	_	_
42	day	_	NOUN	_	Number=Sing	_	_	_	_
43	5	_	NUM	_	NumType=Card	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	evident	_	ADJ	_	Degree=Pos	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	STAT	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	sequences	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	SBE	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	present	_	VERB	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	promoters	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	up	_	ADV	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	regulated	_	VERB	_	Degree=Pos	_	_	_	_
24	during	_	ADP	_	_	_	_	_	_
25	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
28	maturation	_	NOUN	_	Number=Sing	_	_	_	_
29	such	_	ADJ	_	Degree=Pos	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	FcgammaRI	_	PROPN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	promoter	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	transcription	_	NOUN	_	Number=Sing	_	_	_	_
44	factor	_	NOUN	_	Number=Sing	_	_	_	_
45	IFN	_	PROPN	_	Number=Sing	_	_	_	_
46	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
47	factor	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	1.	_	NUM	_	NumType=Card	_	_	_	_
50	Moreover	_	ADV	_	_	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	effect	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	cell	_	NOUN	_	Number=Sing	_	_	_	_
56	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
57	to	_	ADP	_	_	_	_	_	_
58	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
59	or	_	CCONJ	_	_	_	_	_	_
60	laminin	_	NOUN	_	Number=Sing	_	_	_	_
61	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
62	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
63	to	_	PART	_	_	_	_	_	_
64	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
65	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
66	involved	_	ADJ	_	Degree=Pos	_	_	_	_
67	in	_	ADP	_	_	_	_	_	_
68	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
69	activation	_	NOUN	_	Number=Sing	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	Compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	adherent	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	plastic	_	ADJ	_	Degree=Pos	_	_	_	_
7	surfaces	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	freshly	_	ADV	_	_	_	_	_	_
10	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	allowed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	adhere	_	VERB	_	VerbForm=Inf	_	_	_	_
15	either	_	CCONJ	_	_	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	laminin	_	ADJ	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	coated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	flasks	_	NOUN	_	Number=Plur	_	_	_	_
24	exhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	both	_	CCONJ	_	_	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	control	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	IFN	_	ADJ	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	gamma	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	events	_	NOUN	_	Number=Plur	_	_	_	_
4	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
11	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
12	concerned	_	ADJ	_	Degree=Pos	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	Y701	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	S727	_	NUM	_	Number=Sing	_	_	_	_
17	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
18	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
5	growth	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	beta	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
14	effect	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	some	_	DET	_	_	_	_	_	_
17	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	markers	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
23	maturation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	integrin	_	ADJ	_	Degree=Pos	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
8	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	pivotal	_	ADJ	_	Degree=Pos	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	maturation	_	NOUN	_	Number=Sing	_	_	_	_
17	process	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	early	_	ADJ	_	Degree=Pos	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	initially	_	ADV	_	_	_	_	_	_
26	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	adherence	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	then	_	ADV	_	PronType=Dem	_	_	_	_
31	able	_	ADJ	_	Degree=Pos	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	functional	_	ADJ	_	Degree=Pos	_	_	_	_
38	genes	_	NOUN	_	Number=Plur	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	such	_	ADJ	_	Degree=Pos	_	_	_	_
41	as	_	ADP	_	_	_	_	_	_
42	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	FcgammaRI	_	PROPN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001285	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Quantification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
4	D	_	PROPN	_	Number=Sing	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	competitive	_	ADJ	_	Degree=Pos	_	_	_	_
9	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
10	chain	_	NOUN	_	Number=Sing	_	_	_	_
11	reaction	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
14	:	_	PUNCT	_	_	_	_	_	_
15	lack	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	correspondence	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	common	_	ADJ	_	Degree=Pos	_	_	_	_
20	allelic	_	NOUN	_	Degree=Pos	_	_	_	_
21	variants	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	recently	_	ADV	_	_	_	_	_	_
5	claimed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	polymorphism	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
11	D	_	PROPN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	VDR	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	influences	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	several	_	ADJ	_	Degree=Pos	_	_	_	_
18	aspects	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	calcium	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	bone	_	NOUN	_	Number=Sing	_	_	_	_
23	metabolism	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	evaluate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	physiologic	_	ADJ	_	Degree=Pos	_	_	_	_
5	plausibility	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	claims	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	abundance	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	VDR	_	PROPN	_	Number=Sing	_	_	_	_
17	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
20	blood	_	NOUN	_	Number=Sing	_	_	_	_
21	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	PBMCs	_	NOUN	_	Number=Plur	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	between	_	ADP	_	_	_	_	_	_
27	different	_	ADJ	_	Degree=Pos	_	_	_	_
28	VDR	_	NOUN	_	Number=Sing	_	_	_	_
29	genotypes	_	NOUN	_	Number=Plur	_	_	_	_
30	using	_	VERB	_	VerbForm=Ger	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	quantitative	_	ADJ	_	Degree=Pos	_	_	_	_
33	reverse	_	NOUN	_	Number=Sing	_	_	_	_
34	transcribed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
36	chain	_	NOUN	_	Number=Sing	_	_	_	_
37	reaction	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	method	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	method	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	coamplification	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	VDR	_	PROPN	_	Number=Sing	_	_	_	_
10	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	internal	_	ADJ	_	Degree=Pos	_	_	_	_
14	standard	_	ADJ	_	Number=Sing	_	_	_	_
15	consisting	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	VDR	_	PROPN	_	Number=Sing	_	_	_	_
23	CDNA	_	PROPN	_	Number=Sing	_	_	_	_
24	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	at	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	BglII	_	PROPN	_	Number=Sing	_	_	_	_
28	restriction	_	NOUN	_	Number=Sing	_	_	_	_
29	site	_	NOUN	_	Number=Sing	_	_	_	_
30	;	_	PUNCT	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	interassay	_	ADJ	_	Number=Sing	_	_	_	_
33	coefficient	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	variation	_	NOUN	_	Number=Sing	_	_	_	_
36	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	11	_	NUM	_	NumType=Card	_	_	_	_
38	%	_	SYM	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	validate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	method	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	made	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	use	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	earlier	_	ADJ	_	Degree=Cmp	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	studies	_	NOUN	_	Number=Plur	_	_	_	_
14	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	that	_	DET	_	_	_	_	_	_
16	normal	_	ADJ	_	Degree=Pos	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	not	_	ADV	_	_	_	_	_	_
24	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	VDR	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	concentration	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	VDR	_	PROPN	_	Number=Sing	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	10	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	-	_	SYM	_	_	_	_	_	_
11	8	_	NUM	_	NumType=Card	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	10	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	-	_	SYM	_	_	_	_	_	_
17	7	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	g	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	g	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	total	_	ADJ	_	Degree=Pos	_	_	_	_
24	RNA	_	PROPN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	sorted	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
29	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	vitro	_	NOUN	_	Number=Sing	_	_	_	_
34	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	but	_	CCONJ	_	_	_	_	_	_
38	only	_	ADV	_	_	_	_	_	_
39	10	_	NUM	_	NumType=Card	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	-	_	SYM	_	_	_	_	_	_
42	12	_	NUM	_	NumType=Card	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	g	_	NOUN	_	Number=Sing	_	_	_	_
45	/	_	PUNCT	_	_	_	_	_	_
46	g	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	total	_	ADJ	_	Degree=Pos	_	_	_	_
49	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
52	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	establishing	_	VERB	_	VerbForm=Ger	_	_	_	_
55	that	_	SCONJ	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	VDR	_	PROPN	_	Number=Sing	_	_	_	_
58	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
59	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
60	by	_	ADP	_	_	_	_	_	_
61	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
62	method	_	NOUN	_	Number=Sing	_	_	_	_
63	in	_	ADP	_	_	_	_	_	_
64	PBMCs	_	PROPN	_	Number=Sing	_	_	_	_
65	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
66	due	_	ADP	_	_	_	_	_	_
67	to	_	ADP	_	_	_	_	_	_
68	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
69	expression	_	NOUN	_	Number=Sing	_	_	_	_
70	in	_	ADP	_	_	_	_	_	_
71	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
72	.	_	PUNCT	_	_	_	_	_	_

1	Following	_	VERB	_	VerbForm=Ger	_	_	_	_
2	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	initial	_	ADJ	_	Degree=Pos	_	_	_	_
4	genotype	_	NOUN	_	Number=Sing	_	_	_	_
5	screening	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	85	_	NUM	_	NumType=Card	_	_	_	_
8	normal	_	ADJ	_	Degree=Pos	_	_	_	_
9	volunteers	_	NOUN	_	Number=Plur	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
12	chain	_	NOUN	_	Number=Sing	_	_	_	_
13	reaction	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	restriction	_	NOUN	_	Number=Sing	_	_	_	_
16	fragment	_	NOUN	_	Number=Sing	_	_	_	_
17	length	_	NOUN	_	Number=Sing	_	_	_	_
18	polymorphism	_	NOUN	_	Number=Sing	_	_	_	_
19	analysis	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	14	_	NUM	_	NumType=Card	_	_	_	_
22	individuals	_	NOUN	_	Number=Plur	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	Bb	_	NOUN	_	Number=Sing	_	_	_	_
26	genotype	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	12	_	NUM	_	NumType=Card	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	bb	_	NOUN	_	Number=Sing	_	_	_	_
32	genotype	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	12	_	NUM	_	NumType=Card	_	_	_	_
36	with	_	SCONJ	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	BB	_	NOUN	_	Number=Sing	_	_	_	_
39	genotype	_	NOUN	_	Number=Sing	_	_	_	_
40	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	selected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	concentration	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	VDR	_	PROPN	_	Number=Sing	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	corrected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	number	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	similar	_	ADJ	_	Degree=Pos	_	_	_	_
17	among	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	three	_	NUM	_	NumType=Card	_	_	_	_
20	genotype	_	NOUN	_	Number=Sing	_	_	_	_
21	groups	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	as	_	SCONJ	_	_	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	other	_	ADJ	_	Degree=Pos	_	_	_	_
27	variables	_	NOUN	_	Number=Plur	_	_	_	_
28	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	:	_	PUNCT	_	_	_	_	_	_
30	serum	_	NOUN	_	Number=Sing	_	_	_	_
31	calcitriol	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	serum	_	NOUN	_	Number=Sing	_	_	_	_
34	osteocalcin	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	vertebral	_	ADJ	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	hip	_	NOUN	_	Degree=Pos	_	_	_	_
40	bone	_	NOUN	_	Number=Sing	_	_	_	_
41	density	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	VDR	_	PROPN	_	Number=Sing	_	_	_	_
5	polymorphism	_	NOUN	_	Number=Sing	_	_	_	_
6	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	abundance	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	VDR	_	NOUN	_	Number=Sing	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001286	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	localization	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	formation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	beta-catenin	_	ADJ	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
9	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	complexes	_	NOUN	_	Number=Plur	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	response	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Wnt	_	NOUN	_	Number=Sing	_	_	_	_
8	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
9	pathway	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	beta-catenin	_	NOUN	_	Number=Sing	_	_	_	_
12	accumulates	_	VERB	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	where	_	ADV	_	PronType=Rel	_	_	_	_
18	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
19	cooperates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	LEF	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	TCF	_	PROPN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
27	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	factors	_	NOUN	_	Number=Plur	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
37	gene	_	NOUN	_	Number=Sing	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	beta-catenin	_	NOUN	_	Number=Sing	_	_	_	_
6	undergoes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	shift	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	location	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	participates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	beta-catenin	_	NOUN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	imported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	into	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	nucleus	_	ADJ	_	Number=Sing	_	_	_	_
12	independently	_	ADV	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	LEF	_	PROPN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	TCF	_	PROPN	_	Number=Sing	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
21	may	_	AUX	_	VerbForm=Fin	_	_	_	_
22	also	_	ADV	_	_	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	exported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	introduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	small	_	ADJ	_	Degree=Pos	_	_	_	_
6	deletion	_	NOUN	_	Number=Sing	_	_	_	_
7	within	_	ADP	_	_	_	_	_	_
8	beta-catenin	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	Delta19	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	disrupts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	LEF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	E-	_	PUNCT	_	Number=Sing	_	_	_	_
21	cadherin	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	APC	_	NOUN	_	Number=Sing	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	axin	_	ADJ	_	Degree=Pos	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	Delta19	_	PROPN	_	Number=Sing	_	_	_	_
3	beta-catenin	_	PROPN	_	Degree=Pos	_	_	_	_
4	mutant	_	NOUN	_	Number=Sing	_	_	_	_
5	localizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
9	because	_	SCONJ	_	_	_	_	_	_
10	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	efficiently	_	ADV	_	_	_	_	_	_
15	sequestered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	localization	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Delta19	_	PROPN	_	Number=Sing	_	_	_	_
6	definitively	_	ADV	_	_	_	_	_	_
7	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	beta-catenin	_	NOUN	_	Number=Sing	_	_	_	_
14	localizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	completely	_	ADV	_	_	_	_	_	_
20	independent	_	ADJ	_	Degree=Pos	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	LEF	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	TCF	_	PROPN	_	Number=Sing	_	_	_	_
25	factors	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	beta-Catenin	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	LEF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	complexes	_	NOUN	_	Number=Plur	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	reporter	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	T-lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	line	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	normal	_	ADJ	_	Degree=Pos	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	even	_	ADV	_	_	_	_	_	_
29	though	_	SCONJ	_	_	_	_	_	_
30	both	_	DET	_	_	_	_	_	_
31	factors	_	NOUN	_	Number=Plur	_	_	_	_
32	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	localization	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	both	_	DET	_	_	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Excess	_	PROPN	_	_	_	_	_	_
2	beta-catenin	_	NOUN	_	Number=Sing	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	squelch	_	VERB	_	VerbForm=Inf	_	_	_	_
5	reporter	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	LEF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	beta-catenin	_	NOUN	_	Number=Sing	_	_	_	_
14	complexes	_	NOUN	_	Number=Plur	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	VP16	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	third	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
10	component	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	third	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
20	component	_	NOUN	_	Number=Sing	_	_	_	_
21	may	_	AUX	_	VerbForm=Fin	_	_	_	_
22	vary	_	VERB	_	VerbForm=Inf	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	type	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001287	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Every	_	DET	_	_	_	_	_	_
2	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
3	works	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	every	_	DET	_	_	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	all	_	DET	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	combinations	_	NOUN	_	Number=Plur	_	_	_	_
11	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	:	_	PUNCT	_	_	_	_	_	_
13	could	_	AUX	_	VerbForm=Fin	_	_	_	_
14	new	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	pathways	_	NOUN	_	Number=Plur	_	_	_	_
17	evolve	_	VERB	_	VerbForm=Inf	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
20	shuffling	_	NOUN	_	Number=Sing	_	_	_	_
21	?	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	promoters	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	often	_	ADV	_	_	_	_	_	_
13	conserved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	evolution	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	hence	_	ADV	_	_	_	_	_	_
19	one	_	NUM	_	NumType=Card	_	_	_	_
20	might	_	AUX	_	VerbForm=Fin	_	_	_	_
21	expect	_	VERB	_	VerbForm=Inf	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	given	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
26	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	evolved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	work	_	VERB	_	VerbForm=Inf	_	_	_	_
30	best	_	ADV	_	Degree=Sup	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
33	own	_	ADJ	_	Degree=Pos	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	expectation	_	NOUN	_	Number=Sing	_	_	_	_
4	may	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	realized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	some	_	DET	_	_	_	_	_	_
9	cases	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	evidence	_	NOUN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	total	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	27	_	NUM	_	NumType=Card	_	_	_	_
5	combinations	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	different	_	ADJ	_	Degree=Pos	_	_	_	_
8	promoters	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	tested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	transfection	_	NOUN	_	Number=Sing	_	_	_	_
15	into	_	ADP	_	_	_	_	_	_
16	cultured	_	VERB	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	relative	_	ADJ	_	Degree=Pos	_	_	_	_
6	efficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	approximately	_	ADV	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	same	_	ADJ	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	irrespective	_	ADJ	_	_	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	i.e.	_	X	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	there	_	PRON	_	_	_	_	_	_
26	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	no	_	DET	_	_	_	_	_	_
28	strong	_	ADJ	_	Degree=Pos	_	_	_	_
29	preference	_	NOUN	_	Number=Sing	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	any	_	DET	_	_	_	_	_	_
32	given	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	combination	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Notably	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	see	_	VERB	_	VerbForm=Inf	_	_	_	_
7	particularly	_	ADV	_	_	_	_	_	_
8	strong	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	when	_	ADV	_	PronType=Int	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
19	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
20	chain	_	NOUN	_	Number=Sing	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	generally	_	ADV	_	_	_	_	_	_
6	permissive	_	ADJ	_	Degree=Pos	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	interaction	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	evolutionary	_	ADJ	_	Degree=Pos	_	_	_	_
14	benefit	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
17	eukaryotes	_	NOUN	_	Number=Plur	_	_	_	_
18	:	_	PUNCT	_	_	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
21	shuffling	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	could	_	AUX	_	VerbForm=Fin	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	easily	_	ADV	_	_	_	_	_	_
27	brought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	under	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	new	_	ADJ	_	Degree=Pos	_	_	_	_
31	type	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	type	_	NOUN	_	Number=Sing	_	_	_	_
37	specificity	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001291	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Single	_	ADJ	_	Degree=Pos	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	assay	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	reveals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	threshold	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	signals	_	NOUN	_	Number=Plur	_	_	_	_
16	emanating	_	VERB	_	VerbForm=Ger	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
20	antigen	_	NOUN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	through	_	ADP	_	_	_	_	_	_
6	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
7	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	leads	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	appearance	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	several	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	including	_	VERB	_	VerbForm=Ger	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	AT	_	ADP	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	PROPN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	involved	_	ADJ	_	Degree=Pos	_	_	_	_
31	in	_	SCONJ	_	_	_	_	_	_
32	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
33	genes	_	NOUN	_	Number=Plur	_	_	_	_
34	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	immunologic	_	ADJ	_	Degree=Pos	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	single	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	individual	_	ADJ	_	Degree=Pos	_	_	_	_
12	viable	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	applied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	assay	_	NOUN	_	Number=Sing	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	uses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	fluorescence	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	sorter	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	quantitate	_	VERB	_	VerbForm=Inf	_	_	_	_
30	beta-galactosidase	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	beta-gal	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	distribution	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	AT	_	ADP	_	_	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	among	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	undergoing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	SCONJ	_	_	_	_	_	_
18	using	_	VERB	_	VerbForm=Ger	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	construct	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	three	_	NUM	_	NumType=Card	_	_	_	_
24	tandem	_	NOUN	_	Number=Sing	_	_	_	_
25	copies	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	AT	_	ADP	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	binding	_	VERB	_	Number=Sing	_	_	_	_
33	site	_	NOUN	_	Number=Sing	_	_	_	_
34	directs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	lacZ	_	ADJ	_	Degree=Pos	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Unexpectedly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	stably	_	ADV	_	_	_	_	_	_
7	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	bimodal	_	ADJ	_	Degree=Pos	_	_	_	_
15	pattern	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	beta	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	gal	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	some	_	DET	_	_	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	no	_	DET	_	_	_	_	_	_
27	beta-gal	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	others	_	NOUN	_	Number=Plur	_	_	_	_
30	express	_	ADJ	_	Degree=Pos	_	_	_	_
31	high	_	ADJ	_	Degree=Pos	_	_	_	_
32	levels	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	pattern	_	NOUN	_	Number=Sing	_	_	_	_
4	can	_	AUX	_	VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	accounted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	cycle	_	NOUN	_	Number=Sing	_	_	_	_
13	position	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	heritable	_	ADJ	_	Degree=Pos	_	_	_	_
16	variation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	which	_	DET	_	PronType=Rel	_	_	_	_
6	beta-gal	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	AT	_	ADP	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	concentration	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	AT	_	ADV	_	_	_	_	_	_
26	must	_	AUX	_	VerbForm=Fin	_	_	_	_
27	exceed	_	VERB	_	VerbForm=Inf	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	critical	_	ADJ	_	Degree=Pos	_	_	_	_
30	threshold	_	NOUN	_	Number=Sing	_	_	_	_
31	before	_	ADP	_	_	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	initiates	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	threshold	_	NOUN	_	Number=Sing	_	_	_	_
3	likely	_	ADV	_	_	_	_	_	_
4	reflects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	AT	_	ADP	_	_	_	_	_	_
9	concentration	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	assembly	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	complexes	_	NOUN	_	Number=Plur	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	constructs	_	NOUN	_	Number=Plur	_	_	_	_
3	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	entire	_	ADJ	_	Degree=Pos	_	_	_	_
12	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	show	_	VERB	_	Number=Sing	_	_	_	_
17	bimodal	_	ADJ	_	Degree=Pos	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	patterns	_	NOUN	_	Number=Plur	_	_	_	_
20	during	_	ADP	_	_	_	_	_	_
21	induction	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	thresholds	_	NOUN	_	Number=Plur	_	_	_	_
26	set	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	concentration	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	factors	_	NOUN	_	Number=Plur	_	_	_	_
33	may	_	AUX	_	VerbForm=Fin	_	_	_	_
34	be	_	AUX	_	VerbForm=Inf	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	common	_	ADJ	_	Degree=Pos	_	_	_	_
37	property	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
40	genes	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001294	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
6	:	_	PUNCT	_	_	_	_	_	_
7	isolation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
11	transcript	_	NOUN	_	Number=Sing	_	_	_	_
12	encoding	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	autoantigen	_	PROPN	_	Number=Sing	_	_	_	_
16	La	_	PROPN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	SS	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	B	_	PROPN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
24	library	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	patient	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	primary	_	ADJ	_	Degree=Pos	_	_	_	_
30	Sjogrens	_	PROPN	_	Number=Sing	_	_	_	_
31	'	_	PART	_	_	_	_	_	_
32	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
3	library	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
8	blood	_	NOUN	_	Number=Sing	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	autoimmune	_	ADJ	_	Degree=Pos	_	_	_	_
13	patient	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	primary	_	ADJ	_	Degree=Pos	_	_	_	_
16	Sjogrens	_	PROPN	_	Number=Sing	_	_	_	_
17	'	_	PART	_	_	_	_	_	_
18	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
3	library	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	screened	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	patients	_	NOUN	_	Number=Plur	_	_	_	_
9	own	_	ADJ	_	Degree=Pos	_	_	_	_
10	autoimmune	_	ADJ	_	Number=Sing	_	_	_	_
11	serum	_	NOUN	_	Number=Sing	_	_	_	_
12	being	_	AUX	_	VerbForm=Ger	_	_	_	_
13	monospecific	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	autoantigen	_	NOUN	_	Number=Sing	_	_	_	_
18	La	_	PROPN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	SS-B	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Thereby	_	ADV	_	_	_	_	_	_
2	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	La	_	PROPN	_	Number=Sing	_	_	_	_
7	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	differed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	La	_	PROPN	_	Number=Sing	_	_	_	_
16	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
17	due	_	ADP	_	_	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	exchange	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	exon	_	PROPN	_	Number=Sing	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Sequencing	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
5	region	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	exons	_	NOUN	_	Number=Plur	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
16	5	_	NUM	_	NumType=Card	_	_	_	_
17	'-	_	PUNCT	_	_	_	_	_	_
18	end	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	part	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	intron	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	presence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	exists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	within	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	intron	_	NOUN	_	Number=Sing	_	_	_	_
17	downstream	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	exon	_	PROPN	_	Number=Sing	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	became	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	evident	_	ADJ	_	Degree=Pos	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	consequence	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
6	La	_	PROPN	_	Number=Sing	_	_	_	_
7	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	result	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	switching	_	NOUN	_	Number=Sing	_	_	_	_
15	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
19	splicing	_	NOUN	_	Number=Sing	_	_	_	_
20	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	intron	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	further	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
9	sites	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	including	_	VERB	_	VerbForm=Ger	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	element	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	suggestion	_	NOUN	_	Number=Sing	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	encoding	_	VERB	_	Number=Sing	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
35	autoantigen	_	NOUN	_	Number=Sing	_	_	_	_
36	La	_	PROPN	_	Number=Sing	_	_	_	_
37	/	_	PUNCT	_	_	_	_	_	_
38	SS	_	NOUN	_	Number=Sing	_	_	_	_
39	-B	_	NOUN	_	Number=Sing	_	_	_	_
40	alters	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	dependence	_	NOUN	_	Number=Sing	_	_	_	_
43	on	_	ADP	_	_	_	_	_	_
44	disease	_	NOUN	_	Number=Sing	_	_	_	_
45	conditions	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001295	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	promoter	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	5	_	NUM	_	NumType=Card	_	_	_	_
5	'	_	PUNCT	_	_	_	_	_	_
6	flanking	_	NOUN	_	VerbForm=Ger	_	_	_	_
7	sequences	_	NOUN	_	Number=Plur	_	_	_	_
8	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	B29	_	ADJ	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	product	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	B-cell	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	B29	_	PROPN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	B29	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	Ig	_	PROPN	_	Number=Sing	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	CD79b	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	essential	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	Ig	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	via	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	antigen	_	NOUN	_	Number=Sing	_	_	_	_
34	receptor	_	NOUN	_	Number=Sing	_	_	_	_
35	complex	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	BCR	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	on	_	ADP	_	_	_	_	_	_
40	human	_	ADJ	_	Degree=Pos	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	murine	_	NOUN	_	Number=Sing	_	_	_	_
43	B	_	NOUN	_	Number=Sing	_	_	_	_
44	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	better	_	ADV	_	Degree=Cmp	_	_	_	_
3	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	pivotal	_	ADJ	_	Degree=Pos	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
17	DNA	_	PROPN	_	Number=Sing	_	_	_	_
18	sequence	_	NOUN	_	Number=Sing	_	_	_	_
19	upstream	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	B29	_	PROPN	_	Number=Sing	_	_	_	_
23	ATG	_	PROPN	_	Number=Sing	_	_	_	_
24	start	_	NOUN	_	Number=Sing	_	_	_	_
25	codon	_	NOUN	_	Number=Sing	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
28	control	_	NOUN	_	Number=Sing	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	B29	_	PROPN	_	Number=Sing	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	lacks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	either	_	CCONJ	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	TATA	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	CAAT	_	NOUN	_	Number=Sing	_	_	_	_
12	box	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	initiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
19	sites	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	B29	_	PROPN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	contained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	193	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	bp	_	PROPN	_	Number=Sing	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	5	_	NUM	_	NumType=Card	_	_	_	_
18	'	_	NOUN	_	_	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
22	start	_	NOUN	_	Number=Sing	_	_	_	_
23	sites	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	exhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	B-cell	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	SP1	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	ETS	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	OCT	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	IKAROS	_	PROPN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	LYF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	motifs	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	motifs	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	strikingly	_	ADV	_	_	_	_	_	_
6	conserved	_	VERB	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	sequence	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	placement	_	NOUN	_	Number=Sing	_	_	_	_
11	relative	_	ADV	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	previously	_	ADV	_	_	_	_	_	_
15	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	murine	_	NOUN	_	Number=Sing	_	_	_	_
17	B29	_	PROPN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Additional	_	ADJ	_	Degree=Pos	_	_	_	_
2	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	segments	_	NOUN	_	Number=Plur	_	_	_	_
5	dramatically	_	ADV	_	_	_	_	_	_
6	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	B29	_	PROPN	_	NumType=Card	_	_	_	_
8	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	newly	_	ADV	_	_	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	motif	_	NOUN	_	Number=Sing	_	_	_	_
5	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	B29	_	PROPN	_	Number=Sing	_	_	_	_
8	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	sequence	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	BCS	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	upstream	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	murine	_	NOUN	_	Number=Sing	_	_	_	_
21	B29	_	PROPN	_	Number=Sing	_	_	_	_
22	promoters	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	B29	_	PROPN	_	Number=Sing	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	through	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	novel	_	NOUN	_	Number=Sing	_	_	_	_
32	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	single	_	ADJ	_	Degree=Pos	_	_	_	_
3	BCS	_	PROPN	_	Number=Sing	_	_	_	_
4	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	little	_	ADJ	_	Degree=Pos	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	either	_	CCONJ	_	_	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
11	B29	_	PROPN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Instead	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	BCS	_	PROPN	_	Number=Sing	_	_	_	_
5	stimulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	SCONJ	_	_	_	_	_	_
8	counteracting	_	VERB	_	VerbForm=Ger	_	_	_	_
9	5	_	NUM	_	NumType=Card	_	_	_	_
10	'	_	PUNCT	_	_	_	_	_	_
11	negative	_	ADJ	_	Degree=Pos	_	_	_	_
12	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	sequences	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	block	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	B29	_	PROPN	_	Number=Sing	_	_	_	_
22	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	absence	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	B29	_	PROPN	_	Degree=Pos	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	complex	_	ADJ	_	Degree=Pos	_	_	_	_
13	interplay	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	positive	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	negative	_	ADJ	_	Degree=Pos	_	_	_	_
18	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	elements	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001299	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	tissue	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Role	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	AP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	Rel	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	uninduced	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Tissue	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	TF	_	X	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
9	blood	_	NOUN	_	Number=Sing	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
13	initiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	intravascular	_	ADJ	_	Degree=Pos	_	_	_	_
15	thrombosis	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
2	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	LPS	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	rapidly	_	ADV	_	_	_	_	_	_
7	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	TF	_	ADJ	_	_	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	TF	_	NOUN	_	Number=Sing	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	AP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	c	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	Rel	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	p65	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	Egr	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	Rel	_	NOUN	_	Number=Sing	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	physically	_	ADV	_	_	_	_	_	_
13	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	AP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	uninduced	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	LPS	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	TF	_	PROPN	_	Number=Sing	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
25	THP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Deletional	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	five	_	NUM	_	NumType=Card	_	_	_	_
6	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	basal	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	uninduced	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	AP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	bound	_	ADJ	_	Degree=Pos	_	_	_	_
8	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	c	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Jun	_	PROPN	_	Number=Sing	_	_	_	_
13	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	both	_	DET	_	_	_	_	_	_
16	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	LPS	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Maximal	_	ADJ	_	Number=Sing	_	_	_	_
2	LPS	_	PROPN	_	Number=Sing	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	TF	_	PROPN	_	Number=Sing	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	required	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	sites	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	within	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	LPS	_	NOUN	_	Number=Sing	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	element	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Disruption	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	conserved	_	VERB	_	Degree=Pos	_	_	_	_
5	spacing	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	site	_	NOUN	_	Number=Sing	_	_	_	_
18	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	LPS	_	NOUN	_	Number=Sing	_	_	_	_
20	induction	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Replacement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	AP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	sites	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	intrinsically	_	ADV	_	_	_	_	_	_
11	bent	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	partially	_	ADV	_	_	_	_	_	_
14	restored	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	LPS	_	PROPN	_	Number=Sing	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	additional	_	ADJ	_	Degree=Pos	_	_	_	_
21	structural	_	ADJ	_	Degree=Pos	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	AP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	sites	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
2	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	LPS	_	NOUN	_	Number=Sing	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	Drosophila	_	PROPN	_	Number=Sing	_	_	_	_
10	Schneider	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	coexpression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	c	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	Fos	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	c	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	Jun	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	c	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	Rel	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	p65	_	NOUN	_	Number=Sing	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	c	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	Jun	_	PROPN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	p65	_	PROPN	_	Number=Sing	_	_	_	_
35	required	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
38	domains	_	NOUN	_	Number=Plur	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	c	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	Jun	_	PROPN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	p65	_	NUM	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	p65	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
15	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	TF	_	PROPN	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001303	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	IL6	_	PROPN	_	Number=Sing	_	_	_	_
5	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Positive	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	element	_	NOUN	_	Number=Sing	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	PRE	_	X	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	strong	_	ADJ	_	Degree=Pos	_	_	_	_
13	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	essential	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	4	_	NUM	_	NumType=Card	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	PRE	_	X	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	screened	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	library	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	isolated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
25	encoding	_	VERB	_	Number=Sing	_	_	_	_
26	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	IL6	_	PROPN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	also	_	ADV	_	_	_	_	_	_
35	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	as	_	ADP	_	_	_	_	_	_
37	C	_	NOUN	_	Number=Sing	_	_	_	_
38	/	_	PUNCT	_	_	_	_	_	_
39	EBP	_	PROPN	_	Number=Sing	_	_	_	_
40	beta	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	IL6	_	PROPN	_	Number=Sing	_	_	_	_
4	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	mouse	_	NOUN	_	Number=Sing	_	_	_	_
16	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	clone	_	NOUN	_	Number=Sing	_	_	_	_
18	D10	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	not	_	ADV	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	clone	_	NOUN	_	Number=Sing	_	_	_	_
25	29	_	NUM	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	rNF	_	VERB	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	IL6	_	PROPN	_	Number=Sing	_	_	_	_
4	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	bacteria	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	specifically	_	ADV	_	_	_	_	_	_
11	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	PRE	_	X	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	PRE	_	X	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	forms	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
6	DNA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	complexes	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	extracts	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Some	_	DET	_	_	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	complexes	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	IL6	_	PROPN	_	Number=Sing	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	using	_	VERB	_	VerbForm=Ger	_	_	_	_
14	anti-C	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	EBP	_	NOUN	_	Number=Sing	_	_	_	_
17	beta	_	NOUN	_	Number=Sing	_	_	_	_
18	Abs	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	IL6	_	PROPN	_	Number=Sing	_	_	_	_
6	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
11	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
12	transferase	_	NOUN	_	Number=Sing	_	_	_	_
13	reporter	_	NOUN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	PRE	_	X	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	I	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	4	_	NUM	_	NumType=Card	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	more	_	ADJ	_	Degree=Cmp	_	_	_	_
32	than	_	ADP	_	_	_	_	_	_
33	10	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	fold	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Promoter	_	NOUN	_	Number=Sing	_	_	_	_
2	deletion	_	NOUN	_	Number=Sing	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	additional	_	ADJ	_	Degree=Pos	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	IL6	_	PROPN	_	Number=Sing	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	sites	_	NOUN	_	Number=Plur	_	_	_	_
12	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	positions	_	NOUN	_	Number=Plur	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	44	_	NUM	_	NumType=Card	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	-	_	SYM	_	_	_	_	_	_
19	36	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
22	proximal	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	87	_	NUM	_	NumType=Card	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	-	_	SYM	_	_	_	_	_	_
29	79	_	NUM	_	NumType=Card	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
32	medial	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	respectively	_	ADV	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	IL6	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	involved	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	4	_	NUM	_	NumType=Card	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001311	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	11	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	base-pair	_	NOUN	_	Number=Sing	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	motif	_	NOUN	_	Number=Sing	_	_	_	_
8	apparently	_	ADV	_	_	_	_	_	_
9	unique	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	signals	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	DNA	_	NOUN	_	Number=Sing	_	_	_	_
6	segment	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	antigen	_	VERB	_	VerbForm=Inf	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	signals	_	NOUN	_	Number=Plur	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	4	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	kilobases	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	four	_	NUM	_	NumType=Card	_	_	_	_
16	exons	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	three	_	NUM	_	NumType=Card	_	_	_	_
19	introns	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	cis	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	acting	_	NOUN	_	Number=Sing	_	_	_	_
5	element	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	P	_	NOUN	_	Number=Sing	_	_	_	_
8	sequence	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	resides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	5	_	NUM	_	NumType=Card	_	_	_	_
14	'	_	PUNCT	_	_	_	_	_	_
15	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	;	_	PUNCT	_	_	_	_	_	_
18	no	_	DET	_	_	_	_	_	_
19	additional	_	ADJ	_	Degree=Pos	_	_	_	_
20	DNA	_	NOUN	_	Number=Sing	_	_	_	_
21	segments	_	NOUN	_	Number=Plur	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	4	_	NUM	_	NumType=Card	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	further	_	ADJ	_	Degree=Pos	_	_	_	_
3	mapping	_	NOUN	_	Number=Sing	_	_	_	_
4	purposes	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	fusion	_	NOUN	_	Number=Sing	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	constructed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
16	colony	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	basic	_	ADJ	_	Degree=Pos	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	60	_	NUM	_	NumType=Card	_	_	_	_
24	base	_	NOUN	_	Number=Sing	_	_	_	_
25	pairs	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	sequence	_	NOUN	_	Number=Sing	_	_	_	_
28	upstream	_	NOUN	_	Number=Sing	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	cap	_	NOUN	_	Number=Sing	_	_	_	_
32	site	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	mouse	_	NOUN	_	Number=Sing	_	_	_	_
36	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
37	/	_	PUNCT	_	_	_	_	_	_
38	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
39	colony	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
42	factor	_	NOUN	_	Number=Sing	_	_	_	_
43	gene	_	NOUN	_	Number=Sing	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	various	_	ADJ	_	Degree=Pos	_	_	_	_
46	lengths	_	NOUN	_	Number=Plur	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	5	_	NUM	_	NumType=Card	_	_	_	_
50	'	_	PUNCT	_	_	_	_	_	_
51	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
52	sequence	_	NOUN	_	Number=Sing	_	_	_	_
53	of	_	ADP	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	IL	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	4	_	NUM	_	NumType=Card	_	_	_	_
58	gene	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	P	_	NOUN	_	Number=Sing	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	positions	_	NOUN	_	Number=Plur	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	79	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	69	_	NUM	_	NumType=Card	_	_	_	_
13	relative	_	ADV	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	start	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
29	location	_	NOUN	_	Number=Sing	_	_	_	_
30	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
31	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	base	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	substitution	_	NOUN	_	Number=Sing	_	_	_	_
36	mutations	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
3	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
4	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
5	copies	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	P	_	NOUN	_	Number=Sing	_	_	_	_
9	sequence	_	NOUN	_	Number=Sing	_	_	_	_
10	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
12	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	s	_	X	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	recognize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	P	_	NOUN	_	Number=Sing	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	mobility	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	shift	_	NOUN	_	Number=Sing	_	_	_	_
26	assays	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	P	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	DNA	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	specifically	_	ADV	_	_	_	_	_	_
15	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	P	_	NOUN	_	Number=Sing	_	_	_	_
18	sequence	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	P	_	NOUN	_	Number=Sing	_	_	_	_
23	sequence	_	NOUN	_	Number=Sing	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	when	_	ADV	_	PronType=Int	_	_	_	_
27	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
28	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
29	base	_	NOUN	_	Number=Sing	_	_	_	_
30	substitutions	_	NOUN	_	Number=Plur	_	_	_	_
31	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
35	that	_	SCONJ	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	P	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	interaction	_	NOUN	_	Number=Sing	_	_	_	_
42	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
43	sequence	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	specific	_	ADJ	_	Degree=Pos	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
48	binding	_	VERB	_	Number=Sing	_	_	_	_
49	specificity	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	protein	_	NOUN	_	Number=Sing	_	_	_	_
53	paralleled	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	sequence	_	NOUN	_	Number=Sing	_	_	_	_
56	requirements	_	NOUN	_	Number=Plur	_	_	_	_
57	for	_	ADP	_	_	_	_	_	_
58	IL	_	PROPN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	4	_	NUM	_	NumType=Card	_	_	_	_
61	expression	_	NOUN	_	Number=Sing	_	_	_	_
62	in	_	ADP	_	_	_	_	_	_
63	vivo	_	NOUN	_	Number=Sing	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	P	_	NOUN	_	Number=Sing	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	share	_	VERB	_	VerbForm=Inf	_	_	_	_
7	homology	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	5	_	NUM	_	NumType=Card	_	_	_	_
11	'	_	PUNCT	_	_	_	_	_	_
12	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
13	sequence	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	even	_	ADV	_	_	_	_	_	_
22	though	_	SCONJ	_	_	_	_	_	_
23	surrounding	_	VERB	_	VerbForm=Ger	_	_	_	_
24	sequences	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	4	_	NUM	_	NumType=Card	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	share	_	VERB	_	Number=Sing	_	_	_	_
32	high	_	ADJ	_	Degree=Pos	_	_	_	_
33	homology	_	NOUN	_	Number=Sing	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	different	_	ADJ	_	Degree=Pos	_	_	_	_
6	set	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	recognize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001312	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	PPARalpha	_	PROPN	_	Number=Sing	_	_	_	_
2	activators	_	NOUN	_	Number=Plur	_	_	_	_
3	inhibit	_	VERB	_	Number=Sing	_	_	_	_
4	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
10	molecule	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Adhesion	_	NOUN	_	Number=Sing	_	_	_	_
4	molecule	_	NOUN	_	Degree=Pos	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	EC	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	surface	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	critical	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	leukocyte	_	ADJ	_	Degree=Pos	_	_	_	_
18	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	atherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
21	lesions	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Better	_	ADJ	_	Degree=Cmp	_	_	_	_
2	understanding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
8	molecules	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	ECs	_	PROPN	_	Number=Sing	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
13	important	_	ADJ	_	Degree=Pos	_	_	_	_
14	insight	_	NOUN	_	Number=Sing	_	_	_	_
15	into	_	ADP	_	_	_	_	_	_
16	plaque	_	NOUN	_	Number=Sing	_	_	_	_
17	formation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Peroxisome	_	PROPN	_	Degree=Pos	_	_	_	_
2	proliferator	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	PPARalpha	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	member	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	family	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	response	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	certain	_	ADJ	_	Degree=Pos	_	_	_	_
27	fatty	_	ADJ	_	Degree=Pos	_	_	_	_
28	acids	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	fibric	_	NOUN	_	Degree=Pos	_	_	_	_
31	acid	_	NOUN	_	Number=Sing	_	_	_	_
32	derivatives	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	PPARalpha	_	PROPN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	ECs	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
17	molecule	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	AND	_	CCONJ	_	_	_	_	_	_
3	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_
5	Immunohistochemistry	_	NOUN	_	Number=Sing	_	_	_	_
6	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	carotid	_	NOUN	_	Number=Sing	_	_	_	_
10	artery	_	NOUN	_	Number=Sing	_	_	_	_
11	ECs	_	PROPN	_	Number=Sing	_	_	_	_
12	express	_	ADJ	_	Number=Sing	_	_	_	_
13	PPARalpha	_	PROPN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cultured	_	VERB	_	Degree=Pos	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	ECs	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	PPARalpha	_	PROPN	_	Number=Sing	_	_	_	_
9	activators	_	NOUN	_	Number=Plur	_	_	_	_
10	fenofibrate	_	NOUN	_	Number=Sing	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	WY14643	_	NUM	_	Number=Sing	_	_	_	_
13	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	time	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	concentration	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
30	manner	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	effect	_	NOUN	_	Number=Sing	_	_	_	_
34	not	_	ADV	_	_	_	_	_	_
35	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	PPARgamma	_	NOUN	_	Number=Sing	_	_	_	_
38	activators	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	PPARalpha	_	PROPN	_	Number=Sing	_	_	_	_
3	activators	_	NOUN	_	Number=Plur	_	_	_	_
4	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	without	_	SCONJ	_	_	_	_	_	_
14	altering	_	VERB	_	VerbForm=Ger	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
17	half	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	life	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	deletional	_	ADJ	_	Degree=Pos	_	_	_	_
5	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	constructs	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
12	mobility	_	NOUN	_	Number=Sing	_	_	_	_
13	shift	_	NOUN	_	Number=Sing	_	_	_	_
14	assays	_	NOUN	_	Number=Plur	_	_	_	_
15	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	fenofibrate	_	ADJ	_	Degree=Pos	_	_	_	_
18	inhibits	_	VERB	_	Number=Sing	_	_	_	_
19	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	part	_	NOUN	_	Number=Sing	_	_	_	_
25	by	_	SCONJ	_	_	_	_	_	_
26	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	PPARalpha	_	PROPN	_	Number=Sing	_	_	_	_
4	activators	_	NOUN	_	Number=Plur	_	_	_	_
5	significantly	_	ADV	_	_	_	_	_	_
6	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	U937	_	NUM	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	cultured	_	VERB	_	VerbForm=Inf	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	ECs	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Human	_	ADJ	_	Degree=Pos	_	_	_	_
4	ECs	_	PROPN	_	Number=Sing	_	_	_	_
5	express	_	VERB	_	Number=Sing	_	_	_	_
6	PPARalpha	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	potentially	_	ADV	_	_	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulator	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	atherogenesis	_	NOUN	_	Number=Sing	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	control	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Such	_	ADJ	_	Degree=Pos	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	implications	_	NOUN	_	Number=Plur	_	_	_	_
6	regarding	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
9	use	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	lipid	_	NOUN	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	lowering	_	VERB	_	VerbForm=Ger	_	_	_	_
14	agents	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	like	_	ADP	_	_	_	_	_	_
17	fibric	_	NOUN	_	Number=Sing	_	_	_	_
18	acids	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	can	_	AUX	_	VerbForm=Fin	_	_	_	_
22	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	PPARalpha	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001318	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	S	_	PROPN	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	allyl	_	VERB	_	Number=Sing	_	_	_	_
4	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
5	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Reactive	_	ADJ	_	Degree=Pos	_	_	_	_
2	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
3	species	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	involved	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	signal	_	ADJ	_	Number=Sing	_	_	_	_
8	transduction	_	NOUN	_	Number=Sing	_	_	_	_
9	pathways	_	NOUN	_	Number=Plur	_	_	_	_
10	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	regulation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	recently	_	ADV	_	_	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	garlic	_	ADJ	_	Number=Sing	_	_	_	_
7	compound	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	S	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	allyl	_	VERB	_	Number=Sing	_	_	_	_
12	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	SAC	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	protects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	bovine	_	VERB	_	Degree=Pos	_	_	_	_
19	pulmonary	_	ADJ	_	Degree=Pos	_	_	_	_
20	artery	_	NOUN	_	Number=Sing	_	_	_	_
21	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
25	injury	_	NOUN	_	Number=Sing	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	hydrogen	_	ADJ	_	Number=Sing	_	_	_	_
29	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	determined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	SAC	_	PROPN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	Jurkat	_	ADJ	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	tumor	_	NOUN	_	Number=Sing	_	_	_	_
27	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	TNF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	NOUN	_	Number=Sing	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	extracts	_	NOUN	_	Number=Plur	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
10	mobility	_	NOUN	_	Number=Sing	_	_	_	_
11	shift	_	NOUN	_	Number=Sing	_	_	_	_
12	assay	_	NOUN	_	Number=Sing	_	_	_	_
13	using	_	VERB	_	VerbForm=Ger	_	_	_	_
14	32	_	NUM	_	NumType=Card	_	_	_	_
15	P	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	labeled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	probe	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	SAC	_	PROPN	_	Number=Sing	_	_	_	_
2	consistently	_	ADV	_	_	_	_	_	_
3	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	dose	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	TNF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Supershift	_	PROPN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	PROPN	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	subunits	_	NOUN	_	Number=Plur	_	_	_	_
11	confirmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
15	retarded	_	ADJ	_	Degree=Pos	_	_	_	_
16	bands	_	NOUN	_	Number=Plur	_	_	_	_
17	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	p65-p50	_	NUM	_	NumType=Card	_	_	_	_
23	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	Rel	_	NOUN	_	Number=Sing	_	_	_	_
32	protein	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	SAC	_	PROPN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	act	_	VERB	_	VerbForm=Inf	_	_	_	_
8	via	_	ADP	_	_	_	_	_	_
9	antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
10	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	block	_	VERB	_	VerbForm=Inf	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001332	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inducible	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
7	BOB.1	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	OBF.1	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	[	_	PUNCT	_	_	_	_	_	_
14	see	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
15	comments	_	NOUN	_	Number=Plur	_	_	_	_
16	]	_	PUNCT	_	_	_	_	_	_

1	BOB.1/OBF.1	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	constitutively	_	ADV	_	_	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	B	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	interacts	_	VERB	_	Number=Plur	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	Oct1	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	Oct2	_	PROPN	_	Number=Sing	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	primary	_	ADJ	_	Degree=Pos	_	_	_	_
9	murine	_	NOUN	_	Number=Sing	_	_	_	_
10	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
13	esters	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	BOB.1	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	OBF.1	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
23	function	_	NOUN	_	Number=Sing	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	BOB.1/OBF.1	_	NOUN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	at	_	ADP	_	_	_	_	_	_
5	Ser184	_	NUM	_	Number=Sing	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	vivo	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	vitro	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
15	modification	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Ser184	_	PROPN	_	Number=Sing	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	diminished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
7	function	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	B	_	ADJ	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	activating	_	NOUN	_	VerbForm=Ger	_	_	_	_
16	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	constitutively	_	ADV	_	_	_	_	_	_
25	present	_	ADJ	_	Degree=Pos	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	B	_	ADJ	_	Degree=Pos	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	BOB.1/OBF.1	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	critically	_	ADV	_	_	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	posttranslational	_	ADJ	_	Degree=Pos	_	_	_	_
14	modifications	_	NOUN	_	Number=Plur	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001341	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	basis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
6	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
7	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	patient	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	severe	_	ADJ	_	Degree=Pos	_	_	_	_
13	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	child	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	severe	_	ADJ	_	Degree=Pos	_	_	_	_
14	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	defective	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	several	_	ADJ	_	Degree=Pos	_	_	_	_
23	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	IL2	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	IL3	_	PROPN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	IL4	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	IL5	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	which	_	PRON	_	PronType=Rel	_	_	_	_
37	encode	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	interleukins	_	NOUN	_	Number=Plur	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	3	_	NUM	_	NumType=Card	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	4	_	NUM	_	NumType=Card	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	5	_	NUM	_	NumType=Card	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	IL	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	2	_	NUM	_	NumType=Card	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	-	_	SYM	_	_	_	_	_	_
53	3	_	NUM	_	NumType=Card	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	-	_	SYM	_	_	_	_	_	_
56	4	_	NUM	_	NumType=Card	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	and	_	CCONJ	_	_	_	_	_	_
59	-	_	SYM	_	_	_	_	_	_
60	5	_	NUM	_	NumType=Card	_	_	_	_
61	)	_	PUNCT	_	_	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	defect	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	patient	_	NOUN	_	Number=Sing	_	_	_	_
9	's	_	PART	_	_	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	involved	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	trans	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	common	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
26	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	ability	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
31	factors	_	NOUN	_	Number=Plur	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	patient	_	NOUN	_	Number=Sing	_	_	_	_
35	's	_	PART	_	_	_	_	_	_
36	T	_	PROPN	_	Number=Sing	_	_	_	_
37	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
40	response	_	NOUN	_	Number=Sing	_	_	_	_
41	elements	_	NOUN	_	Number=Plur	_	_	_	_
42	present	_	VERB	_	Degree=Pos	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
46	region	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	IL2	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kB	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	OCT	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2B	_	NOUN	_	Number=Sing	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	normal	_	ADJ	_	Degree=Pos	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	AT	_	ADP	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	element	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	IL2	_	PROPN	_	Number=Sing	_	_	_	_
26	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	AT	_	ADP	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	like	_	ADJ	_	_	_	_	_	_
35	response	_	NOUN	_	Number=Sing	_	_	_	_
36	element	_	NOUN	_	Number=Sing	_	_	_	_
37	present	_	VERB	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	IL4	_	PROPN	_	Number=Sing	_	_	_	_
41	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
42	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
43	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	ascertain	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	AT	_	ADP	_	_	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	related	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
16	function	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	transfected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	patient	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	control	_	VERB	_	VerbForm=Inf	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	constructs	_	NOUN	_	Number=Plur	_	_	_	_
27	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	reporter	_	NOUN	_	Number=Sing	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	encoding	_	VERB	_	Number=Sing	_	_	_	_
32	chloramphenicol	_	NOUN	_	Number=Sing	_	_	_	_
33	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
34	transferase	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	CAT	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	under	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	control	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	entire	_	ADJ	_	Degree=Pos	_	_	_	_
44	IL2	_	PROPN	_	Number=Sing	_	_	_	_
45	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
46	region	_	NOUN	_	Number=Sing	_	_	_	_
47	or	_	CCONJ	_	_	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	multimers	_	NOUN	_	Number=Plur	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	individual	_	ADJ	_	Degree=Pos	_	_	_	_
52	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
53	sequences	_	NOUN	_	Number=Plur	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	CAT	_	NOUN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IL2	_	PROPN	_	Number=Sing	_	_	_	_
7	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	region	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	multimer	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	AT	_	ADP	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	markedly	_	ADV	_	_	_	_	_	_
23	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	patient	_	NOUN	_	Number=Sing	_	_	_	_
27	relative	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	controls	_	NOUN	_	VerbForm=Inf	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	CAT	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	multimer	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	OCT	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	proximal	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	OCT	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1p	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	equivalent	_	ADJ	_	Degree=Pos	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	patient	_	ADJ	_	Degree=Pos	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	controls	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	abnormality	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	influencing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	AT	_	PROPN	_	_	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	underlie	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
18	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
19	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	patient	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001342	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Oncogenic	_	ADJ	_	Degree=Pos	_	_	_	_
2	forms	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NOTCH1	_	NOUN	_	Number=Sing	_	_	_	_
5	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
6	either	_	CCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	primary	_	ADJ	_	Degree=Pos	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	RBP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	Jkappa	_	PROPN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	localization	_	NOUN	_	Number=Sing	_	_	_	_
18	sequences	_	NOUN	_	Number=Plur	_	_	_	_
19	retain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	ability	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	associate	_	VERB	_	VerbForm=Inf	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	RBP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	Jkappa	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	forms	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	NOTCH1	_	NOUN	_	Number=Sing	_	_	_	_
6	transmembrane	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	engineered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	resemble	_	VERB	_	VerbForm=Inf	_	_	_	_
11	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
12	forms	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NOTCH1	_	NOUN	_	Number=Sing	_	_	_	_
15	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	certain	_	ADJ	_	Degree=Pos	_	_	_	_
18	cases	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	ALL	_	DET	_	_	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	efficiently	_	ADV	_	_	_	_	_	_
32	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
33	T	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	ALL	_	DET	_	_	_	_	_	_
36	when	_	ADV	_	PronType=Int	_	_	_	_
37	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	bone	_	NOUN	_	Number=Sing	_	_	_	_
41	marrow	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	mice	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Unlike	_	ADP	_	_	_	_	_	_
2	full	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	sized	_	VERB	_	Degree=Pos	_	_	_	_
5	NOTCH1	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	such	_	ADJ	_	Degree=Pos	_	_	_	_
9	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	forms	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	either	_	CCONJ	_	_	_	_	_	_
15	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	major	_	ADJ	_	Degree=Pos	_	_	_	_
18	portion	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	domain	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	DeltaE	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	consisting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	only	_	ADV	_	_	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
32	domain	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	ICN	_	PROPN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
40	transcription	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	cultured	_	VERB	_	Degree=Pos	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	presumably	_	ADV	_	_	_	_	_	_
46	through	_	ADP	_	_	_	_	_	_
47	RBP	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	Jkappa	_	PROPN	_	Number=Sing	_	_	_	_
50	response	_	NOUN	_	Number=Sing	_	_	_	_
51	elements	_	NOUN	_	Number=Plur	_	_	_	_
52	within	_	ADP	_	_	_	_	_	_
53	DNA	_	PROPN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	forms	_	NOUN	_	Number=Plur	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	bound	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	RBP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Jkappa	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	extracts	_	NOUN	_	Number=Plur	_	_	_	_
15	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	murine	_	NOUN	_	Number=Sing	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	ALL	_	DET	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	lines	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	required	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	presence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	weak	_	ADJ	_	Degree=Pos	_	_	_	_
9	RBP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	Jkappa	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	within	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	NOTCH1	_	PROPN	_	Number=Sing	_	_	_	_
18	ankyrin	_	NOUN	_	Number=Sing	_	_	_	_
19	repeat	_	ADJ	_	Degree=Pos	_	_	_	_
20	region	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
24	domain	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Unexpectedly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	stronger	_	ADJ	_	Degree=Cmp	_	_	_	_
7	RBP	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Jkappa	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	lies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	within	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
19	domain	_	NOUN	_	Number=Sing	_	_	_	_
20	close	_	ADJ	_	Degree=Pos	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transmembrane	_	ADJ	_	Number=Sing	_	_	_	_
24	region	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	significantly	_	ADV	_	_	_	_	_	_
27	augments	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	association	_	NOUN	_	Number=Sing	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	RBP	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	Jkappa	_	PROPN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
35	not	_	PART	_	_	_	_	_	_
36	needed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	oncogenesis	_	NOUN	_	Number=Sing	_	_	_	_
39	or	_	CCONJ	_	_	_	_	_	_
40	for	_	ADP	_	_	_	_	_	_
41	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
42	activation	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	ICN	_	PROPN	_	Number=Sing	_	_	_	_
3	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	primarily	_	ADV	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	DeltaE	_	PROPN	_	Number=Sing	_	_	_	_
10	localized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	membranes	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	intranuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	localization	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	essential	_	ADJ	_	Degree=Pos	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	oncogenesis	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	support	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	interpretation	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	mutation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	putative	_	ADJ	_	Degree=Pos	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	localization	_	NOUN	_	Number=Sing	_	_	_	_
12	sequences	_	NOUN	_	Number=Plur	_	_	_	_
13	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	localization	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	membrane	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	bound	_	ADJ	_	Degree=Pos	_	_	_	_
24	DeltaE	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
6	form	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	membrane	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	bound	_	ADJ	_	Degree=Pos	_	_	_	_
11	DeltaE	_	PROPN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	approximately	_	ADV	_	_	_	_	_	_
14	equivalent	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
17	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	intranuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	ICN	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	most	_	ADV	_	_	_	_	_	_
5	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	NOTCH1	_	NOUN	_	Number=Sing	_	_	_	_
8	oncogenesis	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	being	_	AUX	_	VerbForm=Ger	_	_	_	_
13	independent	_	ADJ	_	Degree=Pos	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	association	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	RBP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	Jkappa	_	PROPN	_	Number=Sing	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	sites	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001344	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Impaired	_	ADJ	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	fos	_	ADP	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	jun	_	NOUN	_	Number=Sing	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
18	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
19	c-fos/c	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	jun	_	NOUN	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	elements	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	during	_	ADP	_	_	_	_	_	_
30	aging	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	c-Fos	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	essential	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	normal	_	ADJ	_	Degree=Pos	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	often	_	ADV	_	_	_	_	_	_
22	impaired	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	T	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	during	_	ADP	_	_	_	_	_	_
27	aging	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	whether	_	SCONJ	_	_	_	_	_	_
9	aberrancies	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	level	_	NOUN	_	Number=Sing	_	_	_	_
23	might	_	AUX	_	VerbForm=Fin	_	_	_	_
24	underlie	_	VERB	_	VerbForm=Inf	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	age	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	impairments	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	AP	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	human	_	ADJ	_	Degree=Pos	_	_	_	_
36	T	_	NOUN	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	young	_	ADJ	_	Degree=Pos	_	_	_	_
6	subjects	_	NOUN	_	Number=Plur	_	_	_	_
7	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	cross	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	anti-CD3epsilon	_	NOUN	_	Number=Sing	_	_	_	_
13	mAb	_	PROPN	_	Number=Sing	_	_	_	_
14	OKT3	_	PROPN	_	Number=Sing	_	_	_	_
15	plus	_	CCONJ	_	_	_	_	_	_
16	PMA	_	NOUN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	lectin	_	NOUN	_	Number=Sing	_	_	_	_
21	PHA	_	PROPN	_	Number=Sing	_	_	_	_
22	plus	_	CCONJ	_	_	_	_	_	_
23	PMA	_	PROPN	_	Number=Sing	_	_	_	_
24	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	considerable	_	ADJ	_	Degree=Pos	_	_	_	_
26	increases	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	c	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	Fos	_	ADP	_	Number=Sing	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	c	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	Fos	_	NOUN	_	Number=Sing	_	_	_	_
40	but	_	CCONJ	_	_	_	_	_	_
41	not	_	ADV	_	_	_	_	_	_
42	c	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	Jun	_	PROPN	_	Number=Sing	_	_	_	_
45	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
46	markedly	_	ADV	_	_	_	_	_	_
47	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	T	_	NOUN	_	Number=Sing	_	_	_	_
51	cells	_	NOUN	_	Number=Plur	_	_	_	_
52	from	_	ADP	_	_	_	_	_	_
53	certain	_	ADJ	_	Degree=Pos	_	_	_	_
54	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
55	subjects	_	NOUN	_	Number=Plur	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	RNase	_	PROPN	_	Number=Sing	_	_	_	_
5	protection	_	NOUN	_	Number=Sing	_	_	_	_
6	assays	_	NOUN	_	Number=Plur	_	_	_	_
7	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	PMA	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
6	proportion	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
9	subjects	_	NOUN	_	Number=Plur	_	_	_	_
10	exhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	c	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	fos	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	c	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	jun	_	NOUN	_	Number=Sing	_	_	_	_
23	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
24	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	T	_	PROPN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	young	_	ADJ	_	Degree=Pos	_	_	_	_
30	subjects	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	recognizing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	consensus	_	NOUN	_	Number=Sing	_	_	_	_
19	TRE	_	PROPN	_	Number=Sing	_	_	_	_
20	motif	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
24	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
25	TRE	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	like	_	ADP	_	Degree=Pos	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	element	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
34	serum	_	NOUN	_	Number=Sing	_	_	_	_
35	response	_	NOUN	_	Number=Sing	_	_	_	_
36	element	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	SRE	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	determined	_	ADJ	_	Degree=Pos	_	_	_	_
42	in	_	SCONJ	_	_	_	_	_	_
43	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	T	_	NOUN	_	Number=Sing	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	young	_	ADJ	_	Degree=Pos	_	_	_	_
9	subjects	_	NOUN	_	Number=Plur	_	_	_	_
10	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	coordinated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	increases	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	complexes	_	NOUN	_	Number=Plur	_	_	_	_
18	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	TRE	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
26	TRE	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
30	SRE	_	PROPN	_	Number=Sing	_	_	_	_
31	DNA	_	PROPN	_	Number=Sing	_	_	_	_
32	sequence	_	NOUN	_	Number=Sing	_	_	_	_
33	motifs	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	age	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	related	_	ADJ	_	Degree=Pos	_	_	_	_
38	reductions	_	NOUN	_	Number=Plur	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	activation	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	AP	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
47	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	by	_	ADP	_	_	_	_	_	_
49	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	levels	_	NOUN	_	Number=Plur	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	c	_	NOUN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	jun	_	PROPN	_	Number=Sing	_	_	_	_
55	TRE	_	NOUN	_	Number=Sing	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
58	SRE	_	NOUN	_	Number=Sing	_	_	_	_
59	binding	_	NOUN	_	Number=Sing	_	_	_	_
60	complexes	_	NOUN	_	Number=Plur	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	complexes	_	NOUN	_	Number=Plur	_	_	_	_
7	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	SRE	_	NOUN	_	Number=Sing	_	_	_	_
10	motif	_	NOUN	_	Number=Sing	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	young	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
20	subjects	_	NOUN	_	Number=Plur	_	_	_	_
21	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	serum	_	NOUN	_	Number=Sing	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	Elk	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	pointing	_	VERB	_	VerbForm=Ger	_	_	_	_
30	toward	_	ADP	_	_	_	_	_	_
31	age	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	related	_	ADJ	_	Degree=Pos	_	_	_	_
34	defects	_	NOUN	_	Number=Plur	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
40	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
41	proteins	_	NOUN	_	Number=Plur	_	_	_	_
42	distinct	_	NOUN	_	Number=Sing	_	_	_	_
43	from	_	ADP	_	_	_	_	_	_
44	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
45	/	_	PUNCT	_	_	_	_	_	_
46	AP	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	1	_	NUM	_	NumType=Card	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	underlying	_	ADJ	_	Degree=Pos	_	_	_	_
6	aberrancies	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	c	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	jun	_	NOUN	_	Number=Sing	_	_	_	_
16	as	_	ADV	_	_	_	_	_	_
17	well	_	ADV	_	Degree=Pos	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	may	_	AUX	_	VerbForm=Fin	_	_	_	_
24	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	age	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	related	_	ADJ	_	Degree=Pos	_	_	_	_
30	impairments	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	AP	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	activation	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	human	_	ADJ	_	Degree=Pos	_	_	_	_
38	T	_	NOUN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001359	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Effects	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	lipoic	_	ADJ	_	Number=Sing	_	_	_	_
6	acid	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	dihydrolipoic	_	ADJ	_	Degree=Pos	_	_	_	_
9	acid	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	proto	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
16	c	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	fos	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	mediator	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	serum	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	growth	_	NOUN	_	Number=Sing	_	_	_	_
20	factors	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
24	esters	_	NOUN	_	Number=Plur	_	_	_	_
25	such	_	ADJ	_	Degree=Pos	_	_	_	_
26	as	_	ADP	_	_	_	_	_	_
27	12-O-tetradecanoyl	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	13	_	NUM	_	NumType=Card	_	_	_	_
32	acetate	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	TPA	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	AP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	complex	_	NOUN	_	Number=Sing	_	_	_	_
6	consists	_	VERB	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
11	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	proto	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
17	c	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	fos	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
22	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
23	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	can	_	AUX	_	VerbForm=Fin	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	TPA	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	cyclic	_	ADJ	_	Degree=Pos	_	_	_	_
33	AMP	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	growth	_	NOUN	_	Number=Sing	_	_	_	_
36	factors	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	involvement	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
8	oxygen	_	ADJ	_	Degree=Pos	_	_	_	_
9	species	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	pathway	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	TPA	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	C	_	PROPN	_	Number=Sing	_	_	_	_
19	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	c	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	fos	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	c	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	jun	_	NOUN	_	Number=Sing	_	_	_	_
30	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
7	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
8	species	_	NOUN	_	Number=Plur	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	effects	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	lipoic	_	ADJ	_	Number=Sing	_	_	_	_
17	acid	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	dihydrolipoic	_	ADJ	_	Degree=Pos	_	_	_	_
20	acid	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	natural	_	ADJ	_	Degree=Pos	_	_	_	_
23	thiol	_	NOUN	_	Number=Sing	_	_	_	_
24	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	c	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	fos	_	ADP	_	Number=Sing	_	_	_	_
33	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	human	_	ADJ	_	Degree=Pos	_	_	_	_
36	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
37	T	_	NOUN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	preincubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	dihydrolipoic	_	ADJ	_	Degree=Pos	_	_	_	_
7	acid	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	0.2	_	NUM	_	NumType=Card	_	_	_	_
10	mM	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	c	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	fos	_	ADP	_	Number=Sing	_	_	_	_
18	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	30	_	NUM	_	NumType=Card	_	_	_	_
23	min	_	NOUN	_	Number=Plur	_	_	_	_
24	after	_	ADP	_	_	_	_	_	_
25	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	TPA	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	0.5	_	NUM	_	NumType=Card	_	_	_	_
30	microM	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	whereas	_	SCONJ	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	case	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	preincubation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	alpha-lipoic	_	NOUN	_	Number=Sing	_	_	_	_
40	acid	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	0.2	_	NUM	_	NumType=Card	_	_	_	_
43	microM	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
49	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
50	at	_	ADP	_	_	_	_	_	_
51	30	_	NUM	_	NumType=Card	_	_	_	_
52	min	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	idea	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	superoxide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	anion	_	PROPN	_	Number=Sing	_	_	_	_
9	radical	_	ADV	_	Degree=Pos	_	_	_	_
10	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	c	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	fos	_	ADP	_	Number=Sing	_	_	_	_
20	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001363	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	SLP	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	76	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Vav	_	PROPN	_	Number=Sing	_	_	_	_
6	function	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	separate	_	ADJ	_	Degree=Pos	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	overlapping	_	VERB	_	VerbForm=Ger	_	_	_	_
12	pathways	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	augment	_	VERB	_	VerbForm=Inf	_	_	_	_
15	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	SLP	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	76	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Vav	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	molecules	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	critical	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	T	_	NOUN	_	NumType=Card	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	development	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Following	_	VERB	_	VerbForm=Ger	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	antigen	_	NOUN	_	Number=Sing	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	SLP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	76	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Vav	_	PROPN	_	Number=Sing	_	_	_	_
13	both	_	DET	_	_	_	_	_	_
14	undergo	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
16	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	associate	_	VERB	_	VerbForm=Inf	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	each	_	DET	_	_	_	_	_	_
21	other	_	ADJ	_	Degree=Pos	_	_	_	_
22	via	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	SH2	_	PROPN	_	Number=Sing	_	_	_	_
25	domain	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	Vav	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	tyrosines	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	SLP	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	76	_	NUM	_	NumType=Card	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	SLP	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	76	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	Vav	_	PROPN	_	Number=Sing	_	_	_	_
8	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
11	effect	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	tyrosines	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	Tyr	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	113	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	Tyr	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	128	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	SLP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	76	_	NUM	_	NumType=Card	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	Vav	_	PROPN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	both	_	CCONJ	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	vitro	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	intact	_	ADJ	_	Degree=Pos	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Surprisingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	interaction	_	NOUN	_	Number=Sing	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	SLP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	76	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	Vav	_	PROPN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	SCONJ	_	_	_	_	_	_
22	augmenting	_	VERB	_	VerbForm=Ger	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	as	_	SCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	two	_	NUM	_	NumType=Card	_	_	_	_
32	molecules	_	NOUN	_	Number=Plur	_	_	_	_
33	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	function	_	VERB	_	VerbForm=Inf	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	different	_	ADJ	_	Degree=Pos	_	_	_	_
38	signaling	_	NOUN	_	Number=Sing	_	_	_	_
39	pathways	_	NOUN	_	Number=Plur	_	_	_	_
40	upstream	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	2	_	NUM	_	NumType=Card	_	_	_	_
45	gene	_	NOUN	_	Number=Sing	_	_	_	_
46	expression	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	SLP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	76	_	NUM	_	NumType=Card	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	potentiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	activities	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	both	_	DET	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	AP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Vav	_	PROPN	_	Number=Sing	_	_	_	_
7	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	without	_	SCONJ	_	_	_	_	_	_
18	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	AP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_
23	Additionally	_	ADV	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	Vav	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	not	_	ADV	_	_	_	_	_	_
31	SLP	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	76	_	NUM	_	NumType=Card	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	augments	_	NOUN	_	Number=Plur	_	_	_	_
36	CD28	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	IL	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	activity	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	synergy	_	NOUN	_	Number=Sing	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	SLP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	76	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Vav	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	SCONJ	_	_	_	_	_	_
14	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	reflects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
23	between	_	ADP	_	_	_	_	_	_
24	different	_	ADJ	_	Degree=Pos	_	_	_	_
25	signaling	_	NOUN	_	Number=Sing	_	_	_	_
26	pathways	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001365	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	:	_	PUNCT	_	_	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
17	activators	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
4	viruses	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	HIVs	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	include	_	VERB	_	VerbForm=Inf	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	spectrum	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	retroviruses	_	NOUN	_	Number=Plur	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	varying	_	ADJ	_	VerbForm=Ger	_	_	_	_
16	potential	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	infect	_	VERB	_	VerbForm=Inf	_	_	_	_
19	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	host	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	undergo	_	VERB	_	VerbForm=Inf	_	_	_	_
23	long	_	ADJ	_	Degree=Pos	_	_	_	_
24	periods	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	latent	_	ADJ	_	Degree=Pos	_	_	_	_
27	infection	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	induce	_	VERB	_	Degree=Pos	_	_	_	_
31	pathology	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	viruses	_	NOUN	_	Number=Plur	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	large	_	ADJ	_	Degree=Pos	_	_	_	_
9	part	_	NOUN	_	Number=Sing	_	_	_	_
10	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	sequence	_	NOUN	_	Number=Sing	_	_	_	_
14	elements	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	long	_	ADJ	_	Degree=Pos	_	_	_	_
18	terminal	_	NOUN	_	Number=Sing	_	_	_	_
19	repeats	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	study	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	directed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	analysis	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
34	elements	_	NOUN	_	Number=Plur	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	HIV	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	LTR	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	HIV	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	LTR	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
5	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	part	_	ADJ	_	Degree=Pos	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	identical	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	HIV	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	;	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	HIV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	however	_	ADV	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
25	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	mainly	_	ADV	_	_	_	_	_	_
29	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	response	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
36	activators	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
4	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	85	_	NUM	_	NumType=Card	_	_	_	_
12	kD	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	27	_	NUM	_	NumType=Card	_	_	_	_
15	kD	_	NOUN	_	Number=Sing	_	_	_	_
16	mobility	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
25	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
26	function	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Observations	_	NOUN	_	Number=Plur	_	_	_	_
2	such	_	ADJ	_	Degree=Pos	_	_	_	_
3	as	_	SCONJ	_	_	_	_	_	_
4	these	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
5	encourage	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	speculation	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	there	_	PRON	_	_	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	be	_	VERB	_	VerbForm=Inf	_	_	_	_
12	subtle	_	ADJ	_	Degree=Pos	_	_	_	_
13	differences	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	may	_	AUX	_	VerbForm=Fin	_	_	_	_
28	be	_	AUX	_	VerbForm=Inf	_	_	_	_
29	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	possible	_	ADJ	_	Degree=Pos	_	_	_	_
33	longer	_	ADJ	_	Degree=Cmp	_	_	_	_
34	latency	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	pathogenicity	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	HIV	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_
43	Document	_	NOUN	_	Number=Sing	_	_	_	_
44	003001371	_	NUM	_	NumType=Card	_	_	_	_
45	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Engagement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	Lewis	_	PROPN	_	Number=Sing	_	_	_	_
5	X	_	PROPN	_	_	_	_	_	_
6	antigen	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	CD15	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	results	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
6	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	tumor	_	VERB	_	VerbForm=Inf	_	_	_	_
9	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	tissue	_	ADJ	_	Number=Sing	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	CD36	_	NOUN	_	Number=Sing	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	immunological	_	ADJ	_	Degree=Pos	_	_	_	_
3	cross	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	mimic	_	VERB	_	VerbForm=Inf	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	engagement	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	natural	_	ADJ	_	Degree=Pos	_	_	_	_
12	ligands	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	now	_	ADV	_	_	_	_	_	_
16	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	CD15	_	PROPN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	Lewis	_	PROPN	_	Number=Sing	_	_	_	_
21	X	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
26	counter	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	receptor	_	NOUN	_	Number=Sing	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
31	selectins	_	NOUN	_	Number=Plur	_	_	_	_
32	may	_	AUX	_	VerbForm=Fin	_	_	_	_
33	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
36	response	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
4	production	_	NOUN	_	Number=Sing	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	readout	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	CD15	_	PROPN	_	Number=Sing	_	_	_	_
15	cross	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	linking	_	VERB	_	Number=Sing	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	TNF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	release	_	NOUN	_	Number=Sing	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
25	blood	_	NOUN	_	Number=Sing	_	_	_	_
26	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	line	_	NOUN	_	Number=Sing	_	_	_	_
34	MM6	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Quantitative	_	ADJ	_	Degree=Pos	_	_	_	_
2	reverse	_	NOUN	_	Number=Sing	_	_	_	_
3	transcriptase	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
6	chain	_	NOUN	_	Number=Sing	_	_	_	_
7	reaction	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	RT	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	PCR	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	increase	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	steady	_	ADJ	_	Degree=Pos	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	state	_	NOUN	_	Number=Sing	_	_	_	_
20	TNF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
24	after	_	ADP	_	_	_	_	_	_
25	3	_	NUM	_	NumType=Card	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	4	_	NUM	_	NumType=Card	_	_	_	_
28	hours	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	cross	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	linking	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	CD15	_	PROPN	_	Number=Sing	_	_	_	_
2	cross	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	concomitantly	_	ADV	_	_	_	_	_	_
7	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	beta	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	while	_	SCONJ	_	_	_	_	_	_
21	no	_	DET	_	_	_	_	_	_
22	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
23	change	_	NOUN	_	Number=Sing	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	levels	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	beta-actin	_	ADJ	_	Number=Sing	_	_	_	_
31	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
34	specificity	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
7	genes	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	CD15	_	PROPN	_	Number=Sing	_	_	_	_
10	engagement	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	CAT	_	NOUN	_	Number=Sing	_	_	_	_
14	plasmid	_	VERB	_	Degree=Pos	_	_	_	_
15	reporter	_	NOUN	_	Number=Sing	_	_	_	_
16	construct	_	NOUN	_	Number=Sing	_	_	_	_
17	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	beta	_	NOUN	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
25	sequences	_	NOUN	_	Number=Plur	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	introduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	into	_	ADP	_	_	_	_	_	_
29	MM6	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
2	cross	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	linking	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CD15	_	PROPN	_	Number=Sing	_	_	_	_
7	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	CAT	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	CD15	_	PROPN	_	Number=Sing	_	_	_	_
2	engagement	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	monoclonal	_	ADJ	_	Number=Sing	_	_	_	_
5	antibody	_	NOUN	_	Number=Sing	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	attenuated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	transcript	_	NOUN	_	Number=Sing	_	_	_	_
13	degradation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	signaling	_	VERB	_	Number=Sing	_	_	_	_
18	via	_	ADP	_	_	_	_	_	_
19	CD15	_	PROPN	_	Number=Sing	_	_	_	_
20	also	_	ADV	_	_	_	_	_	_
21	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	effects	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	extracts	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	anti-CD15	_	PROPN	_	Number=Sing	_	_	_	_
5	cross	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	activator	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	minimally	_	ADV	_	_	_	_	_	_
22	changed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	not	_	PART	_	_	_	_	_	_
32	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
33	SV40	_	PROPN	_	Number=Sing	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	specific	_	ADJ	_	Degree=Pos	_	_	_	_
36	protein	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	engagement	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CD15	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
9	results	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
5	well	_	ADV	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	recognized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	adhesive	_	ADJ	_	Degree=Pos	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	CD15	_	PROPN	_	Number=Sing	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	function	_	VERB	_	VerbForm=Inf	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	important	_	ADJ	_	Degree=Pos	_	_	_	_
17	signaling	_	NOUN	_	Number=Sing	_	_	_	_
18	molecule	_	NOUN	_	Number=Sing	_	_	_	_
19	capable	_	ADJ	_	Degree=Pos	_	_	_	_
20	of	_	SCONJ	_	_	_	_	_	_
21	initiating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	events	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	come	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	into	_	ADP	_	_	_	_	_	_
29	contact	_	NOUN	_	Number=Sing	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001372	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Vitamin	_	PROPN	_	Number=Sing	_	_	_	_
2	E	_	NOUN	_	Number=Sing	_	_	_	_
3	therapy	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	acute	_	ADJ	_	Degree=Pos	_	_	_	_
6	CCl4	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	hepatic	_	ADJ	_	Degree=Pos	_	_	_	_
10	injury	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	mice	_	NOUN	_	Number=Plur	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
2	stress	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
6	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
7	intermediate	_	ADJ	_	Degree=Pos	_	_	_	_
8	formation	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	common	_	ADJ	_	Degree=Pos	_	_	_	_
14	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	liver	_	NOUN	_	Number=Sing	_	_	_	_
18	injury	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
23	etiologies	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
2	stress	_	NOUN	_	Number=Sing	_	_	_	_
3	enhances	_	VERB	_	Number=Plur	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	NF	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
31	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Acute	_	ADJ	_	Degree=Pos	_	_	_	_
2	hepatic	_	ADJ	_	Degree=Pos	_	_	_	_
3	injury	_	NOUN	_	Number=Sing	_	_	_	_
4	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
7	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
8	intermediate	_	ADJ	_	Degree=Pos	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	intraperitoneal	_	ADJ	_	Degree=Pos	_	_	_	_
15	injection	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	CCl4	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	mice	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	injury	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	significantly	_	ADV	_	_	_	_	_	_
5	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	intravenous	_	ADJ	_	Degree=Pos	_	_	_	_
8	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	mice	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	water	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
17	emulsion	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	alpha-tocopherol	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Alpha	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	tocopherol	_	NOUN	_	Number=Sing	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	mice	_	NOUN	_	Number=Plur	_	_	_	_
8	given	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	CCl4	_	NOUN	_	Number=Sing	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	reduced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	levels	_	NOUN	_	Number=Plur	_	_	_	_
21	approaching	_	VERB	_	VerbForm=Ger	_	_	_	_
22	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
23	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	normal	_	ADJ	_	Degree=Pos	_	_	_	_
26	mice	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	treatment	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	CCl4	_	NOUN	_	Number=Sing	_	_	_	_
13	led	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	increase	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	tumor	_	NOUN	_	Number=Sing	_	_	_	_
26	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	TNF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	messenger	_	NOUN	_	Number=Sing	_	_	_	_
36	RNA	_	PROPN	_	Number=Sing	_	_	_	_
37	levels	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Liver	_	NOUN	_	Number=Sing	_	_	_	_
2	specimens	_	NOUN	_	Number=Plur	_	_	_	_
3	taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	patients	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	acute	_	ADJ	_	Degree=Pos	_	_	_	_
8	fulminant	_	ADJ	_	Degree=Pos	_	_	_	_
9	hepatitis	_	NOUN	_	Number=Sing	_	_	_	_
10	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	markedly	_	ADV	_	_	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	comparison	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	normal	_	ADJ	_	Degree=Pos	_	_	_	_
26	livers	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	abolishing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	acute	_	ADJ	_	Degree=Pos	_	_	_	_
7	hepatic	_	ADJ	_	Degree=Pos	_	_	_	_
8	injury	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	tocopherol	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	free	_	ADJ	_	Degree=Pos	_	_	_	_
16	radical	_	ADJ	_	Degree=Pos	_	_	_	_
17	scavenger	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	eliminated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	tempting	_	ADJ	_	Degree=Pos	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	speculate	_	VERB	_	VerbForm=Inf	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	free	_	ADJ	_	Degree=Pos	_	_	_	_
16	radical	_	ADJ	_	Degree=Pos	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
20	stress	_	NOUN	_	Number=Sing	_	_	_	_
21	may	_	AUX	_	VerbForm=Fin	_	_	_	_
22	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	liver	_	NOUN	_	Number=Sing	_	_	_	_
24	injury	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	perhaps	_	ADV	_	_	_	_	_	_
27	through	_	ADP	_	_	_	_	_	_
28	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	effect	_	NOUN	_	Number=Sing	_	_	_	_
30	on	_	ADP	_	_	_	_	_	_
31	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
32	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
33	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001380	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Fludarabine	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	immunosuppression	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
11	signaling	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Fludarabine	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	nucleoside	_	NOUN	_	Number=Sing	_	_	_	_
5	analog	_	NOUN	_	Number=Sing	_	_	_	_
6	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	treatment	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	hematologic	_	ADJ	_	Degree=Pos	_	_	_	_
12	malignancies	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
16	severe	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	prolonged	_	VERB	_	Degree=Pos	_	_	_	_
19	immunosuppression	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	incorporated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	into	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	DNA	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	dividing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	fludarabine	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	potent	_	ADJ	_	Degree=Pos	_	_	_	_
18	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	low	_	ADJ	_	Degree=Pos	_	_	_	_
24	growth	_	NOUN	_	Number=Sing	_	_	_	_
25	fraction	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	thus	_	ADV	_	_	_	_	_	_
28	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
29	must	_	AUX	_	VerbForm=Fin	_	_	_	_
30	have	_	VERB	_	VerbForm=Inf	_	_	_	_
31	other	_	ADJ	_	Degree=Pos	_	_	_	_
32	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	action	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	which	_	PRON	_	PronType=Rel	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	many	_	ADJ	_	Degree=Pos	_	_	_	_
10	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
14	including	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	interferons	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	essential	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
24	immunity	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	as	_	SCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	absence	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	prominent	_	ADJ	_	Degree=Pos	_	_	_	_
36	defects	_	NOUN	_	Number=Plur	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	ability	_	NOUN	_	Number=Sing	_	_	_	_
40	to	_	PART	_	_	_	_	_	_
41	control	_	VERB	_	VerbForm=Inf	_	_	_	_
42	viral	_	ADJ	_	Degree=Pos	_	_	_	_
43	infections	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	fludarabine	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	but	_	CCONJ	_	_	_	_	_	_
8	not	_	ADV	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	immunosuppressant	_	ADJ	_	Degree=Pos	_	_	_	_
11	cyclosporine	_	NOUN	_	Number=Sing	_	_	_	_
12	A	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	normal	_	ADJ	_	Degree=Pos	_	_	_	_
30	resting	_	NOUN	_	Number=Sing	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Fludarabine	_	PROPN	_	Number=Sing	_	_	_	_
2	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	depletion	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	other	_	ADJ	_	Degree=Pos	_	_	_	_
17	STATs	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	loss	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	patients	_	NOUN	_	Number=Sing	_	_	_	_
12	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	fludarabine	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	vivo	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Brief	_	ADJ	_	Degree=Pos	_	_	_	_
2	exposure	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	fludarabine	_	NOUN	_	Number=Sing	_	_	_	_
5	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	sustained	_	VERB	_	Degree=Pos	_	_	_	_
9	loss	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	analogous	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	prolonged	_	ADJ	_	Degree=Pos	_	_	_	_
17	period	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	immunosuppression	_	NOUN	_	Number=Sing	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	exposure	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	drug	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	vivo	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
4	may	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	useful	_	ADJ	_	Degree=Pos	_	_	_	_
8	target	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	development	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	new	_	ADJ	_	Degree=Pos	_	_	_	_
14	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	antineoplastic	_	ADJ	_	Degree=Pos	_	_	_	_
17	agents	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001385	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	patients	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	rheumatic	_	ADJ	_	Degree=Pos	_	_	_	_
14	diseases	_	NOUN	_	Number=Plur	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_

1	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	preliminary	_	ADJ	_	Degree=Pos	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	OBJECTIVE	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	Rel	_	NOUN	_	Number=Sing	_	_	_	_
10	family	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	many	_	ADJ	_	Degree=Pos	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	immune	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
26	response	_	NOUN	_	Number=Sing	_	_	_	_
27	at	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
30	level	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	aim	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
9	whether	_	SCONJ	_	_	_	_	_	_
10	distinctive	_	ADJ	_	Degree=Pos	_	_	_	_
11	patterns	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	different	_	ADJ	_	Degree=Pos	_	_	_	_
22	forms	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	joint	_	ADJ	_	Degree=Pos	_	_	_	_
25	disease	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	binding	_	VERB	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	nucleoproteins	_	NOUN	_	Number=Plur	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	patients	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	various	_	ADJ	_	Degree=Pos	_	_	_	_
23	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
24	rheumatic	_	ADJ	_	Number=Sing	_	_	_	_
25	diseases	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	12	_	NUM	_	NumType=Card	_	_	_	_
28	:	_	PUNCT	_	_	_	_	_	_
29	four	_	NUM	_	NumType=Card	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	rheumatoid	_	NOUN	_	Number=Sing	_	_	_	_
32	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
33	;	_	PUNCT	_	_	_	_	_	_
34	five	_	NUM	_	NumType=Card	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	spondyloarthropathies	_	NOUN	_	Number=Plur	_	_	_	_
37	;	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	three	_	NUM	_	NumType=Card	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	osteoarthritis	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
4	mobility	_	NOUN	_	Number=Sing	_	_	_	_
5	shift	_	NOUN	_	Number=Sing	_	_	_	_
6	assays	_	NOUN	_	Number=Plur	_	_	_	_
7	disclosed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	complexes	_	NOUN	_	Number=Plur	_	_	_	_
11	bound	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	32P	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	labelled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	nucleoproteins	_	NOUN	_	Number=Plur	_	_	_	_
25	extracted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	T	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
33	fluid	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
36	blood	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	patients	_	NOUN	_	Number=Plur	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	rheumatoid	_	NOUN	_	Number=Sing	_	_	_	_
41	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	complexes	_	NOUN	_	Number=Plur	_	_	_	_
3	consisted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	p50/p50	_	NUM	_	NumType=Card	_	_	_	_
6	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
9	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	NOUN	_	Number=Sing	_	_	_	_
2	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	relative	_	ADV	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	non-rheumatoid	_	ADJ	_	Degree=Pos	_	_	_	_
3	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	exclusively	_	ADV	_	_	_	_	_	_
17	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	p50/p50	_	NUM	_	NumType=Card	_	_	_	_
20	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSION	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	Overall	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	play	_	VERB	_	VerbForm=Inf	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	central	_	ADJ	_	Degree=Pos	_	_	_	_
15	part	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	SCONJ	_	_	_	_	_	_
20	infiltrating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	chronic	_	ADJ	_	Number=Sing	_	_	_	_
25	rheumatoid	_	NOUN	_	Number=Sing	_	_	_	_
26	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	qualitatively	_	ADV	_	_	_	_	_	_
9	different	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	rheumatoid	_	ADJ	_	Degree=Pos	_	_	_	_
12	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	forms	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	non-rheumatoid	_	ADJ	_	Degree=Pos	_	_	_	_
22	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	example	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	osteoarthritis	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	spondyloarthropathies	_	NOUN	_	Number=Plur	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001386	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	4	_	NUM	_	NumType=Card	_	_	_	_
3	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	signal	_	ADJ	_	Number=Sing	_	_	_	_
6	transducer	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	activator	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	Stat	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	interferon	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	gamma	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	like	_	ADP	_	Degree=Pos	_	_	_	_
26	sequence	_	NOUN	_	Number=Sing	_	_	_	_
27	upstream	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	I	_	PRON	_	NumType=Card	_	_	_	_
31	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
32	exon	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	human	_	ADJ	_	Degree=Pos	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	line	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	involvement	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Janus	_	PROPN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	Stat	_	PROPN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Germ	_	NOUN	_	Number=Sing	_	_	_	_
2	line	_	NOUN	_	Number=Sing	_	_	_	_
3	C	_	NOUN	_	Number=Sing	_	_	_	_
4	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
5	can	_	AUX	_	VerbForm=Fin	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	line	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	BL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Utilizing	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	IFN	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	gamma	_	NOUN	_	Number=Sing	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	like	_	ADP	_	_	_	_	_	_
10	DNA	_	PROPN	_	Number=Sing	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	upstream	_	ADP	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	I	_	PRON	_	NumType=Card	_	_	_	_
18	epsilon	_	VERB	_	Number=Sing	_	_	_	_
19	exon	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
22	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	gel	_	NOUN	_	Number=Sing	_	_	_	_
25	mobility	_	NOUN	_	Number=Sing	_	_	_	_
26	shift	_	NOUN	_	Number=Sing	_	_	_	_
27	assays	_	NOUN	_	Number=Plur	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	4	_	NUM	_	NumType=Card	_	_	_	_
32	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	binding	_	VERB	_	Number=Sing	_	_	_	_
35	activity	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	BL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	2	_	NUM	_	NumType=Card	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	designated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	NAF	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	activating	_	NOUN	_	VerbForm=Ger	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
26	phosphoprotein	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	translocates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
36	upon	_	ADP	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	4	_	NUM	_	NumType=Card	_	_	_	_
40	treatment	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	these	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	signal	_	ADJ	_	Number=Sing	_	_	_	_
9	transducer	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	activator	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	Stat	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	determined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	whether	_	SCONJ	_	_	_	_	_	_
22	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	Stat	_	PROPN	_	Number=Sing	_	_	_	_
25	proteins	_	NOUN	_	Number=Plur	_	_	_	_
26	will	_	AUX	_	VerbForm=Fin	_	_	_	_
27	interfere	_	VERB	_	VerbForm=Inf	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	gel	_	NOUN	_	Number=Sing	_	_	_	_
30	mobility	_	NOUN	_	Number=Sing	_	_	_	_
31	shift	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	that	_	SCONJ	_	_	_	_	_	_
35	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	4	_	NUM	_	NumType=Card	_	_	_	_
40	Stat	_	PROPN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	also	_	ADV	_	_	_	_	_	_
43	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	as	_	ADP	_	_	_	_	_	_
45	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	but	_	CCONJ	_	_	_	_	_	_
48	not	_	ADV	_	_	_	_	_	_
49	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	other	_	ADJ	_	Degree=Pos	_	_	_	_
52	Stat	_	PROPN	_	Number=Sing	_	_	_	_
53	proteins	_	NOUN	_	Number=Plur	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	interfere	_	VERB	_	VerbForm=Inf	_	_	_	_
56	with	_	ADP	_	_	_	_	_	_
57	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
58	formation	_	NOUN	_	Number=Sing	_	_	_	_
59	of	_	ADP	_	_	_	_	_	_
60	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
61	IL	_	PROPN	_	Number=Sing	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	4	_	NUM	_	NumType=Card	_	_	_	_
64	NAF	_	PROPN	_	Number=Sing	_	_	_	_
65	complex	_	NOUN	_	Number=Sing	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	Congruous	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	involvement	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	Stat	_	PROPN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	robust	_	ADJ	_	Degree=Pos	_	_	_	_
15	Janus	_	PROPN	_	Number=Sing	_	_	_	_
16	kinase	_	NOUN	_	Number=Sing	_	_	_	_
17	3	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	JAK3	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	BL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	JAK3	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	Stat	_	PROPN	_	Number=Sing	_	_	_	_
9	into	_	ADP	_	_	_	_	_	_
10	COS	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	7	_	NUM	_	NumType=Card	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	bound	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	same	_	ADJ	_	Degree=Pos	_	_	_	_
22	IFN	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	gamma	_	NOUN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	site	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	like	_	ADP	_	Degree=Pos	_	_	_	_
29	sequence	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	comigrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	4	_	NUM	_	NumType=Card	_	_	_	_
36	NAF	_	PROPN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
39	mobility	_	NOUN	_	Number=Sing	_	_	_	_
40	shift	_	NOUN	_	Number=Sing	_	_	_	_
41	assay	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	NAF	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	Stat	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	JAK3	_	PROPN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	4	_	NUM	_	NumType=Card	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	engagement	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001387	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Limited	_	ADJ	_	Degree=Pos	_	_	_	_
2	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	SCONJ	_	_	_	_	_	_
4	assaying	_	VERB	_	VerbForm=Ger	_	_	_	_
5	ligand	_	NOUN	_	Number=Sing	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	affinities	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	receptors	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	natural	_	ADJ	_	Degree=Pos	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
7	ligands	_	NOUN	_	Number=Plur	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	receptors	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	triggering	_	VERB	_	Number=Sing	_	_	_	_
14	event	_	NOUN	_	Number=Sing	_	_	_	_
15	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	repression	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Ligand	_	PROPN	_	Number=Sing	_	_	_	_
2	binding	_	VERB	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	ligand	_	NOUN	_	Number=Sing	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	domain	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
10	receptors	_	NOUN	_	Number=Plur	_	_	_	_
11	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	conformational	_	ADJ	_	Degree=Pos	_	_	_	_
13	changes	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	evidenced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	resistance	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
23	domain	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	proteases	_	VERB	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	labeled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	receptors	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	incubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	various	_	ADJ	_	Degree=Pos	_	_	_	_
9	synthetic	_	NOUN	_	Degree=Pos	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	natural	_	ADJ	_	Degree=Pos	_	_	_	_
12	agonists	_	NOUN	_	Number=Plur	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	antagonists	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	submitted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	trypsin	_	VERB	_	Number=Sing	_	_	_	_
19	digestion	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Proteolysis	_	PROPN	_	Number=Sing	_	_	_	_
2	products	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	separated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	SDS	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	PAGE	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	quantified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	amount	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	trypsin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
7	fragments	_	NOUN	_	Number=Plur	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	proportional	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	receptor	_	VERB	_	VerbForm=Inf	_	_	_	_
12	occupancy	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	ligand	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	allowed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	determination	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
23	constants	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	kDa	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	wild	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	mutated	_	VERB	_	Degree=Pos	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	retinoic	_	NOUN	_	Number=Sing	_	_	_	_
10	acid	_	NOUN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	model	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	kDa	_	NOUN	_	Number=Sing	_	_	_	_
18	values	_	NOUN	_	Number=Plur	_	_	_	_
19	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	classical	_	ADJ	_	Degree=Pos	_	_	_	_
22	competition	_	NOUN	_	Number=Sing	_	_	_	_
23	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
24	assays	_	NOUN	_	Number=Plur	_	_	_	_
25	using	_	VERB	_	VerbForm=Ger	_	_	_	_
26	tritiated	_	ADJ	_	Degree=Pos	_	_	_	_
27	ligands	_	NOUN	_	Number=Plur	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	agreement	_	NOUN	_	Number=Sing	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
33	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	proteolytic	_	ADJ	_	Number=Sing	_	_	_	_
37	assay	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	method	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	successfully	_	ADV	_	_	_	_	_	_
5	extended	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	retinoic	_	NOUN	_	Number=Sing	_	_	_	_
9	X	_	SYM	_	_	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	thus	_	ADV	_	_	_	_	_	_
21	providing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	basis	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	new	_	ADJ	_	Degree=Pos	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	faster	_	ADJ	_	Degree=Cmp	_	_	_	_
29	assay	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
32	simultaneously	_	ADV	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	affinity	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	conformation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	receptors	_	NOUN	_	Number=Plur	_	_	_	_
39	when	_	ADV	_	PronType=Int	_	_	_	_
40	bound	_	ADJ	_	Degree=Pos	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	given	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	ligand	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001393	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Isolation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	candidate	_	NOUN	_	Number=Sing	_	_	_	_
5	repressor	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	activator	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	E1	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	YY	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	delta	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	3	_	NUM	_	NumType=Card	_	_	_	_
27	'	_	PUNCT	_	_	_	_	_	_
28	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
32	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	chain	_	NOUN	_	Number=Sing	_	_	_	_
35	mu	_	NOUN	_	Number=Sing	_	_	_	_
36	E1	_	NOUN	_	Number=Sing	_	_	_	_
37	site	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
7	control	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	immunoglobulin	_	PROPN	_	Number=Sing	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	'	_	PUNCT	_	_	_	_	_	_
13	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	E3	_	NOUN	_	Number=Sing	_	_	_	_
17	'	_	PUNCT	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	result	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	influence	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	positive	_	ADJ	_	Degree=Pos	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	negative	_	ADJ	_	Degree=Pos	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	acting	_	VERB	_	Number=Sing	_	_	_	_
34	elements	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	central	_	ADJ	_	Degree=Pos	_	_	_	_
6	core	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	E3	_	NOUN	_	Number=Sing	_	_	_	_
11	'	_	PUNCT	_	_	_	_	_	_
12	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	active	_	ADJ	_	Degree=Pos	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	stage	_	NOUN	_	Number=Sing	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	repressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	flanking	_	VERB	_	VerbForm=Ger	_	_	_	_
26	negative	_	ADJ	_	Degree=Pos	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
29	elements	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	negative	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
5	sequences	_	NOUN	_	Number=Plur	_	_	_	_
6	repress	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	position	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	orientation	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	independent	_	ADJ	_	Degree=Pos	_	_	_	_
17	manner	_	NOUN	_	Number=Sing	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	pre	_	NUM	_	_	_	_	_	_
21	-B	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	stage	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
7	clone	_	NOUN	_	Number=Sing	_	_	_	_
8	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	zinc	_	NOUN	_	Number=Sing	_	_	_	_
11	finger	_	NOUN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	E1	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	negative	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	segment	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	kappa	_	PROPN	_	Number=Sing	_	_	_	_
29	E3	_	NOUN	_	Number=Sing	_	_	_	_
30	'	_	PUNCT	_	_	_	_	_	_
31	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
8	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	chain	_	NOUN	_	Number=Sing	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	mu	_	NOUN	_	Number=Sing	_	_	_	_
13	E1	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	E1	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	encoded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	same	_	ADJ	_	Degree=Pos	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	YY	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	adeno	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	virus	_	NOUN	_	Number=Sing	_	_	_	_
25	P5	_	NOUN	_	Number=Sing	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	E1	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	homologue	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	mouse	_	NOUN	_	Number=Sing	_	_	_	_
12	delta	_	NOUN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	ribosomal	_	ADJ	_	Degree=Pos	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	promoters	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	predicted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	amino	_	NOUN	_	Number=Sing	_	_	_	_
4	acid	_	VERB	_	Number=Sing	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	features	_	NOUN	_	Number=Plur	_	_	_	_
11	characteristic	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	activators	_	NOUN	_	Number=Plur	_	_	_	_
15	as	_	ADV	_	_	_	_	_	_
16	well	_	ADV	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
19	repressors	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
2	studies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
6	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	repress	_	VERB	_	VerbForm=Inf	_	_	_	_
11	basal	_	ADJ	_	Degree=Pos	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
3	dual	_	ADJ	_	Degree=Pos	_	_	_	_
4	function	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001403	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cyclosporin	_	VERB	_	Number=Sing	_	_	_	_
2	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	interferes	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
7	degradation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	not	_	ADV	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	processing	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	p105	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B1	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	T	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	controls	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	numerous	_	ADJ	_	Degree=Pos	_	_	_	_
13	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
14	promoters	_	NOUN	_	Number=Plur	_	_	_	_
15	during	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	immunosuppressants	_	NOUN	_	Number=Plur	_	_	_	_
9	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
10	A	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	CsA	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	FK506	_	PROPN	_	Number=Sing	_	_	_	_
16	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	suppressive	_	ADJ	_	Degree=Pos	_	_	_	_
19	effect	_	NOUN	_	Number=Sing	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	induction	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
32	promoters	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	as	_	ADV	_	_	_	_	_	_
11	well	_	ADV	_	Degree=Pos	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	mouse	_	NOUN	_	Number=Sing	_	_	_	_
16	primary	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
23	effect	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	impaired	_	VERB	_	Degree=Pos	_	_	_	_
29	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
30	translocation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	Rel	_	PROPN	_	Number=Sing	_	_	_	_
34	proteins	_	PROPN	_	Number=Plur	_	_	_	_
35	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	RelA	_	PROPN	_	Number=Sing	_	_	_	_
38	/	_	PUNCT	_	_	_	_	_	_
39	p65	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	NF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	kappa	_	PROPN	_	Number=Sing	_	_	_	_
44	B1/p50	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	whereas	_	SCONJ	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
49	appearance	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	RelB	_	PROPN	_	Number=Sing	_	_	_	_
52	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
53	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	CsA	_	PROPN	_	Number=Sing	_	_	_	_
2	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	interfere	_	VERB	_	VerbForm=Inf	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Rel	_	NOUN	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
16	degradation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	kappa	_	VERB	_	Number=Sing	_	_	_	_
26	B	_	PROPN	_	Number=Sing	_	_	_	_
27	alpha	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
30	kappa	_	VERB	_	Number=Sing	_	_	_	_
31	B	_	PROPN	_	Number=Sing	_	_	_	_
32	beta	_	NOUN	_	Number=Sing	_	_	_	_
33	upon	_	ADP	_	_	_	_	_	_
34	T	_	PROPN	_	Number=Sing	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	activation	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	CsA	_	PROPN	_	Number=Sing	_	_	_	_
2	neither	_	CCONJ	_	_	_	_	_	_
3	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	processing	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_

1	B1	_	PROPN	_	NumType=Card	_	_	_	_
2	precursor	_	PROPN	_	Number=Sing	_	_	_	_
3	p105	_	NUM	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	p50	_	NUM	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	nor	_	CCONJ	_	_	_	_	_	_
8	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
10	"	_	PUNCT	_	_	_	_	_	_
11	stabilize	_	VERB	_	VerbForm=Inf	_	_	_	_
12	"	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	C	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	terminal	_	NOUN	_	Number=Sing	_	_	_	_
17	portion	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	p105	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	kappa	_	VERB	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	gamma	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	which	_	PRON	_	PronType=Rel	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	degraded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	during	_	ADP	_	_	_	_	_	_
30	p105	_	NOUN	_	Number=Sing	_	_	_	_
31	processing	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	mature	_	VERB	_	VerbForm=Inf	_	_	_	_
34	p50	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CsA	_	PROPN	_	Number=Sing	_	_	_	_
6	interferes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	event	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	signal	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	degradation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	kappa	_	VERB	_	Number=Sing	_	_	_	_
20	B	_	PROPN	_	Number=Sing	_	_	_	_
21	alpha	_	PROPN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
24	kappa	_	VERB	_	Number=Sing	_	_	_	_
25	B	_	PROPN	_	Number=Sing	_	_	_	_
26	beta	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	but	_	CCONJ	_	_	_	_	_	_
29	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	not	_	PART	_	_	_	_	_	_
31	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	processing	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B1	_	NOUN	_	Number=Sing	_	_	_	_
39	/	_	PUNCT	_	_	_	_	_	_
40	p105	_	NOUN	_	Number=Sing	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	p50	_	NUM	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001406	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Suppression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
6	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	myricetin	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	other	_	ADJ	_	Degree=Pos	_	_	_	_
12	flavonoids	_	NOUN	_	Number=Plur	_	_	_	_
13	through	_	SCONJ	_	_	_	_	_	_
14	downregulating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	IKK	_	PROPN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	ECV304	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Flavonoids	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	group	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	naturally	_	ADV	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
9	phenolic	_	ADJ	_	Degree=Pos	_	_	_	_
10	compounds	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	plant	_	NOUN	_	Number=Sing	_	_	_	_
14	kingdom	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	many	_	ADJ	_	Degree=Pos	_	_	_	_
18	flavonoids	_	NOUN	_	Number=Plur	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
23	protective	_	ADJ	_	Degree=Pos	_	_	_	_
24	properties	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Nevertheless	_	ADV	_	_	_	_	_	_
2	how	_	ADV	_	PronType=Int	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	protective	_	ADJ	_	Degree=Pos	_	_	_	_
5	response	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	exerted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	flavonoids	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	well	_	ADV	_	Degree=Pos	_	_	_	_
13	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	view	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	play	_	VERB	_	VerbForm=Inf	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	central	_	ADJ	_	Degree=Pos	_	_	_	_
16	role	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	initiation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	prevention	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
29	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	important	_	ADJ	_	Degree=Pos	_	_	_	_
32	role	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	SCONJ	_	_	_	_	_	_
34	protecting	_	VERB	_	VerbForm=Ger	_	_	_	_
35	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
36	injury	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	flavonoids	_	NOUN	_	Number=Plur	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	IkappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	system	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	ECV304	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	tumor	_	NOUN	_	Number=Sing	_	_	_	_
25	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
5	action	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	six	_	NUM	_	NumType=Card	_	_	_	_
8	flavonoids	_	NOUN	_	Number=Plur	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IKK	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
19	recently	_	ADV	_	_	_	_	_	_
20	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	phosphorylate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	critical	_	ADJ	_	Degree=Pos	_	_	_	_
24	serine	_	NOUN	_	Number=Sing	_	_	_	_
25	residues	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	degradation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Of	_	ADP	_	_	_	_	_	_
2	six	_	NUM	_	NumType=Card	_	_	_	_
3	flavonoids	_	NOUN	_	Number=Plur	_	_	_	_
4	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	myricetin	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	strongly	_	ADV	_	_	_	_	_	_
11	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
12	IKK	_	PROPN	_	Number=Sing	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	degradation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	IkappaBbeta	_	PROPN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	myricetin	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
9	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	suppression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
16	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	ECV304	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	flavonoids	_	NOUN	_	Number=Plur	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
10	value	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
13	disease	_	NOUN	_	Number=Sing	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	down	_	ADP	_	_	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
21	system	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1999	_	NUM	_	NumType=Card	_	_	_	_
3	Wiley	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	Liss	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	Inc.	_	PROPN	_	Number=Sing	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	003001407	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Structural	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	functional	_	ADJ	_	Degree=Pos	_	_	_	_
4	characterization	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	CD36	_	PROPN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	identification	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
16	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	CBF	_	NOUN	_	Number=Sing	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	CD36	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	surface	_	NOUN	_	Number=Sing	_	_	_	_
6	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
7	composed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	single	_	ADJ	_	Degree=Pos	_	_	_	_
11	polypeptide	_	NOUN	_	Number=Sing	_	_	_	_
12	chain	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	thrombospondin	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	collagens	_	NOUN	_	Number=Plur	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	IV	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	oxidized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	low	_	ADJ	_	Degree=Pos	_	_	_	_
27	density	_	NOUN	_	Number=Sing	_	_	_	_
28	lipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	fatty	_	ADJ	_	Degree=Pos	_	_	_	_
31	acids	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	anionic	_	ADJ	_	Degree=Pos	_	_	_	_
34	phospholipids	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	erythrocytes	_	NOUN	_	Number=Plur	_	_	_	_
38	parasitized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	Plasmodium	_	PROPN	_	Number=Sing	_	_	_	_
41	falciparum	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	few	_	ADJ	_	Degree=Pos	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	types	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	including	_	VERB	_	VerbForm=Ger	_	_	_	_
12	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	CD36	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	involved	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	phagocytosis	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	foam	_	NOUN	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	formation	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	uptake	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	oxidized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	low	_	ADJ	_	Degree=Pos	_	_	_	_
23	density	_	NOUN	_	Number=Sing	_	_	_	_
24	lipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	study	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	CD36	_	PROPN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
18	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	CD36	_	NOUN	_	Number=Sing	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	5'-	_	NUM	_	NumType=Card	_	_	_	_
6	deletion	_	NOUN	_	Number=Sing	_	_	_	_
7	fragments	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	CD36	_	PROPN	_	Number=Sing	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
15	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	as	_	ADV	_	_	_	_	_	_
18	few	_	ADJ	_	Degree=Pos	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	158	_	NUM	_	NumType=Card	_	_	_	_
21	base	_	NOUN	_	Number=Sing	_	_	_	_
22	pairs	_	NOUN	_	Number=Plur	_	_	_	_
23	upstream	_	NOUN	_	_	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	initiation	_	NOUN	_	Number=Sing	_	_	_	_
28	site	_	NOUN	_	Number=Sing	_	_	_	_
29	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	direct	_	VERB	_	VerbForm=Inf	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	specific	_	ADJ	_	Degree=Pos	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	reporter	_	NOUN	_	Number=Sing	_	_	_	_
41	gene	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Within	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	above	_	ADJ	_	Degree=Pos	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	fragment	_	NOUN	_	Number=Sing	_	_	_	_
8	spanning	_	VERB	_	VerbForm=Ger	_	_	_	_
9	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	158	_	NUM	_	NumType=Card	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	90	_	NUM	_	NumType=Card	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	region	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	158/-90	_	NUM	_	NumType=Card	_	_	_	_
8	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	polyomavirus	_	PROPN	_	Number=Sing	_	_	_	_
18	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	core	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	CBF	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	family	_	NOUN	_	Number=Sing	_	_	_	_
34	at	_	ADP	_	_	_	_	_	_
35	position	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	103	_	NUM	_	NumType=Card	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Disruption	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	PEBP2	_	PROPN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	CBF	_	PROPN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	markedly	_	ADV	_	_	_	_	_	_
9	diminished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	CBF	_	NOUN	_	Number=Sing	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	CD36	_	NOUN	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	involvement	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	members	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	PEBP2	_	PROPN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	CBF	_	PROPN	_	Number=Sing	_	_	_	_
10	family	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
13	translocations	_	NOUN	_	Number=Plur	_	_	_	_
14	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	acute	_	ADJ	_	Degree=Pos	_	_	_	_
17	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
18	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
24	regulation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	specific	_	ADJ	_	Degree=Pos	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	myeloperoxidase	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	elastase	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	colony	_	ADJ	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
42	factor	_	NOUN	_	Number=Sing	_	_	_	_
43	receptor	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	highlights	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	relevance	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	regulation	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	CD36	_	PROPN	_	Number=Sing	_	_	_	_
54	gene	_	NOUN	_	Number=Sing	_	_	_	_
55	promoter	_	NOUN	_	Number=Sing	_	_	_	_
56	in	_	ADP	_	_	_	_	_	_
57	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
58	cells	_	NOUN	_	Number=Plur	_	_	_	_
59	by	_	ADP	_	_	_	_	_	_
60	members	_	NOUN	_	Number=Plur	_	_	_	_
61	of	_	ADP	_	_	_	_	_	_
62	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
63	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
64	/	_	PUNCT	_	_	_	_	_	_
65	CBF	_	PROPN	_	Number=Sing	_	_	_	_
66	family	_	NOUN	_	Number=Sing	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001412	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	functional	_	ADJ	_	Degree=Pos	_	_	_	_
6	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	genes	_	NOUN	_	Number=Plur	_	_	_	_
6	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	:	_	PUNCT	_	_	_	_	_	_
10	c	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	fos	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	c	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	jun	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	formation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	AP1	_	NOUN	_	Number=Sing	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	complex	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	strongly	_	ADV	_	_	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	c-jun	_	NOUN	_	Degree=Pos	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	as	_	ADV	_	_	_	_	_	_
14	well	_	ADV	_	Degree=Pos	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	AP1	_	NOUN	_	Number=Sing	_	_	_	_
17	formation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
2	gamma	_	NOUN	_	Number=Sing	_	_	_	_
3	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	strongly	_	ADV	_	_	_	_	_	_
5	c	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	fos	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	weakly	_	ADV	_	Degree=Pos	_	_	_	_
10	c	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	jun	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	AP1	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	slightly	_	ADV	_	_	_	_	_	_
6	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	almost	_	ADV	_	_	_	_	_	_
10	no	_	DET	_	_	_	_	_	_
11	effect	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	c	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	jun	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	AP1	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	differences	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	functional	_	ADJ	_	Degree=Pos	_	_	_	_
8	responses	_	NOUN	_	Number=Plur	_	_	_	_
9	elicited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	all	_	DET	_	_	_	_	_	_
14	three	_	NUM	_	NumType=Card	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	different	_	ADJ	_	Degree=Pos	_	_	_	_
21	routes	_	NOUN	_	Number=Plur	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	signalling	_	NOUN	_	Number=Sing	_	_	_	_
25	employed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001416	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	modulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	at	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	level	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	modulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	several	_	ADJ	_	Degree=Pos	_	_	_	_
14	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	level	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	view	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	findings	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	effects	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	IFN	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	gamma	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	different	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Priming	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	down	_	X	_	Degree=Pos	_	_	_	_
13	regulation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	c	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	fos	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	c-jun	_	NOUN	_	Degree=Pos	_	_	_	_
20	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	LPS	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	effects	_	NOUN	_	Number=Plur	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	LPS	_	NOUN	_	Number=Sing	_	_	_	_
36	alone	_	ADV	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Not	_	ADV	_	_	_	_	_	_
2	only	_	ADV	_	_	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	at	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
10	level	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	activator	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	DNA	_	NOUN	_	Number=Sing	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	capacity	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	as	_	ADV	_	_	_	_	_	_
28	well	_	ADV	_	Degree=Pos	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	strong	_	ADJ	_	Degree=Pos	_	_	_	_
32	reduction	_	NOUN	_	Number=Sing	_	_	_	_
33	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
34	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	LPS	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	DNA	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	binding	_	VERB	_	Number=Sing	_	_	_	_
43	activity	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	AP	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	presence	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	IFN	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	gamma	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	p105	_	NOUN	_	Number=Sing	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	precursor	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	p50	_	NUM	_	Number=Sing	_	_	_	_
18	subunit	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	PROPN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	while	_	SCONJ	_	_	_	_	_	_
36	no	_	DET	_	_	_	_	_	_
37	effect	_	NOUN	_	Number=Sing	_	_	_	_
38	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
39	noticed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	on	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	expression	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	p65	_	NUM	_	Number=Sing	_	_	_	_
45	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	IFN	_	ADJ	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	gamma	_	NOUN	_	Number=Sing	_	_	_	_
7	priming	_	NOUN	_	Number=Sing	_	_	_	_
8	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	p105	_	NOUN	_	Number=Sing	_	_	_	_
15	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	p65	_	NUM	_	Number=Sing	_	_	_	_
22	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	two	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	fold	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Priming	_	VERB	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	IFN	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	gamma	_	NOUN	_	Number=Sing	_	_	_	_
6	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	LPS	_	NOUN	_	Number=Sing	_	_	_	_
9	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	further	_	ADJ	_	Degree=Pos	_	_	_	_
14	increase	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	p65	_	NUM	_	Number=Sing	_	_	_	_
20	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	due	_	ADP	_	_	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	increase	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	half	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	life	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	p65	_	NOUN	_	Number=Sing	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	75	_	NUM	_	NumType=Card	_	_	_	_
17	vs	_	ADP	_	Abbr=Yes	_	_	_	_
18	150	_	NUM	_	NumType=Card	_	_	_	_
19	minutes	_	NOUN	_	Number=Plur	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EMSAs	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	predominantly	_	ADV	_	_	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	p50	_	NUM	_	Number=Sing	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B.	_	PROPN	_	Number=Sing	_	_	_	_
19	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	LPS	_	NOUN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	IFN	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	gamma	_	NOUN	_	Number=Sing	_	_	_	_
26	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	p50	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	p65	_	NUM	_	Number=Sing	_	_	_	_
34	subunits	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	while	_	SCONJ	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	combination	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	IFN	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	gamma	_	NOUN	_	Number=Sing	_	_	_	_
43	plus	_	CCONJ	_	_	_	_	_	_
44	LPS	_	PROPN	_	Number=Sing	_	_	_	_
45	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
46	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
47	further	_	ADJ	_	Degree=Pos	_	_	_	_
48	increase	_	NOUN	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	expression	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	NF	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	kappa	_	NOUN	_	Number=Sing	_	_	_	_
56	B.	_	PROPN	_	Number=Sing	_	_	_	_
57	With	_	ADP	_	_	_	_	_	_
58	Western	_	ADJ	_	Degree=Pos	_	_	_	_
59	blotting	_	NOUN	_	Number=Sing	_	_	_	_
60	,	_	PUNCT	_	_	_	_	_	_
61	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
62	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
63	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
64	that	_	SCONJ	_	_	_	_	_	_
65	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
66	extracts	_	NOUN	_	Number=Plur	_	_	_	_
67	from	_	ADP	_	_	_	_	_	_
68	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
69	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
70	p50	_	NOUN	_	Number=Sing	_	_	_	_
71	and	_	CCONJ	_	_	_	_	_	_
72	p65	_	NUM	_	Number=Sing	_	_	_	_
73	protein	_	NOUN	_	Number=Sing	_	_	_	_
74	in	_	ADP	_	_	_	_	_	_
75	response	_	NOUN	_	Number=Sing	_	_	_	_
76	to	_	ADP	_	_	_	_	_	_
77	LPS	_	NOUN	_	Number=Sing	_	_	_	_
78	and	_	CCONJ	_	_	_	_	_	_
79	IFN	_	PROPN	_	Number=Sing	_	_	_	_
80	-	_	PUNCT	_	_	_	_	_	_
81	gamma	_	NOUN	_	Number=Sing	_	_	_	_
82	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
83	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	result	_	VERB	_	VerbForm=Inf	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	p50	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	p65	_	NUM	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IFN	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	gamma	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	since	_	SCONJ	_	_	_	_	_	_
15	no	_	DET	_	_	_	_	_	_
16	change	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	6	_	NUM	_	NumType=Card	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
30	kappa	_	VERB	_	Number=Sing	_	_	_	_
31	B	_	PROPN	_	Number=Sing	_	_	_	_
32	alpha	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kappa	_	PROPN	_	Number=Sing	_	_	_	_
40	B	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	gamma	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	AP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	may	_	AUX	_	VerbForm=Fin	_	_	_	_
26	be	_	AUX	_	VerbForm=Inf	_	_	_	_
27	important	_	ADJ	_	Degree=Pos	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	modulatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	effects	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	IFN	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	gamma	_	NOUN	_	Number=Sing	_	_	_	_
36	on	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	human	_	ADJ	_	Degree=Pos	_	_	_	_
43	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001420	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Potent	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	stable	_	ADJ	_	Degree=Pos	_	_	_	_
4	attenuation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	live	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	gain	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
18	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	alphaS32/36A	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	implications	_	NOUN	_	Number=Plur	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	vaccine	_	NOUN	_	Number=Sing	_	_	_	_
33	development	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Live	_	VERB	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	attenuated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	viruses	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HIVs	_	NOUN	_	Number=Plur	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	candidates	_	NOUN	_	Number=Plur	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	Acquired	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	Immunodeficiency	_	PROPN	_	Number=Sing	_	_	_	_
15	Syndrome	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	vaccine	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	simian	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	SIV	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	model	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	loss	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	function	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	e.g.	_	X	_	_	_	_	_	_
21	deletion	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	accessory	_	ADJ	_	Degree=Pos	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	such	_	ADJ	_	Degree=Pos	_	_	_	_
26	as	_	ADP	_	_	_	_	_	_
27	nef	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
31	forwarded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	primary	_	ADJ	_	Degree=Pos	_	_	_	_
35	approach	_	NOUN	_	Number=Sing	_	_	_	_
36	for	_	SCONJ	_	_	_	_	_	_
37	creating	_	VERB	_	VerbForm=Ger	_	_	_	_
38	enfeebled	_	ADJ	_	Degree=Pos	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	but	_	CCONJ	_	_	_	_	_	_
41	replication	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	competent	_	ADJ	_	Degree=Pos	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	HIV	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1/SIV	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Regrettably	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	recent	_	ADJ	_	Degree=Pos	_	_	_	_
4	evidence	_	NOUN	_	Number=Sing	_	_	_	_
5	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	loss	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	function	_	NOUN	_	Number=Sing	_	_	_	_
12	alone	_	ADJ	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	always	_	ADV	_	_	_	_	_	_
16	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	emergence	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	virulent	_	ADJ	_	Degree=Pos	_	_	_	_
23	mutants	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	New	_	ADJ	_	Degree=Pos	_	_	_	_
2	strategies	_	NOUN	_	Number=Plur	_	_	_	_
3	that	_	PRON	_	PronType=Rel	_	_	_	_
4	attenuate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	via	_	ADP	_	_	_	_	_	_
6	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
7	distinct	_	ADJ	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	loss	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	function	_	NOUN	_	Number=Sing	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	needed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	for	_	SCONJ	_	_	_	_	_	_
17	enhancing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	safety	_	NOUN	_	Number=Sing	_	_	_	_
20	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	viral	_	ADJ	_	Degree=Pos	_	_	_	_
23	genome	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	gain	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	function	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	simultaneously	_	ADV	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	loss	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	function	_	NOUN	_	Number=Sing	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	novel	_	NOUN	_	Number=Sing	_	_	_	_
23	approach	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	SCONJ	_	_	_	_	_	_
25	attenuating	_	VERB	_	VerbForm=Ger	_	_	_	_
26	HIV	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	constructed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	genome	_	NOUN	_	Number=Sing	_	_	_	_
9	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alphaS32/36A	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	nef	_	ADJ	_	Number=Sing	_	_	_	_
30	region	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alphaS32/36A	_	NOUN	_	Number=Sing	_	_	_	_
8	down	_	ADV	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	viral	_	ADJ	_	Degree=Pos	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	highly	_	ADV	_	_	_	_	_	_
16	attenuated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	Jurkat	_	ADJ	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
22	blood	_	NOUN	_	Number=Sing	_	_	_	_
23	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	formal	_	ADJ	_	Degree=Pos	_	_	_	_
4	proof	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	attenuating	_	VERB	_	Degree=Pos	_	_	_	_
10	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	alphaS32	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	36	_	NUM	_	NumType=Card	_	_	_	_
17	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	permit	_	VERB	_	Number=Sing	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	stable	_	ADJ	_	Degree=Pos	_	_	_	_
21	maintenance	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	live	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	replicating	_	VERB	_	VerbForm=Ger	_	_	_	_
27	HIV	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	despite	_	ADP	_	_	_	_	_	_
31	180	_	NUM	_	NumType=Card	_	_	_	_
32	days	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	forced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	ex	_	NOUN	_	Number=Sing	_	_	_	_
36	vivo	_	NOUN	_	Number=Sing	_	_	_	_
37	passaging	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	tissue	_	ADJ	_	Number=Sing	_	_	_	_
40	culture	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	other	_	ADJ	_	Degree=Pos	_	_	_	_
5	open	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	reading	_	VERB	_	VerbForm=Ger	_	_	_	_
8	frames	_	NOUN	_	Number=Plur	_	_	_	_
9	embedded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	into	_	ADP	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	SIV	_	NOUN	_	Number=Sing	_	_	_	_
14	genome	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	degree	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	stability	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	unprecedented	_	ADJ	_	Degree=Pos	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	alphaS32/36A	_	NOUN	_	Number=Sing	_	_	_	_
6	offers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	proof	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	principle	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	artifactually	_	ADV	_	_	_	_	_	_
14	gained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	functions	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	when	_	ADV	_	PronType=Int	_	_	_	_
18	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	attenuate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	replication	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	live	_	ADJ	_	Degree=Pos	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	can	_	AUX	_	VerbForm=Fin	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	stable	_	ADJ	_	Degree=Pos	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	illustrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	gain	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	function	_	NOUN	_	Number=Sing	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	feasible	_	ADJ	_	Degree=Pos	_	_	_	_
12	strategy	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	SCONJ	_	_	_	_	_	_
14	developing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	safer	_	ADJ	_	Degree=Cmp	_	_	_	_
16	live	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	attenuated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	HIVs	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	tested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	candidates	_	NOUN	_	Number=Plur	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
27	vaccine	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001421	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Control	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	kappa	_	VERB	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	signal	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
2	kappa	_	VERB	_	Number=Sing	_	_	_	_
3	B	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	alpha	_	PROPN	_	Number=Sing	_	_	_	_
6	inhibits	_	NOUN	_	Number=Sing	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	retaining	_	VERB	_	VerbForm=Ger	_	_	_	_
15	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Various	_	ADJ	_	Degree=Pos	_	_	_	_
2	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	typically	_	ADV	_	_	_	_	_	_
5	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
6	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	stress	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	pathogens	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	rapidly	_	ADV	_	_	_	_	_	_
13	inactivate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	kappa	_	VERB	_	Number=Sing	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	liberates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	translocate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	important	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	defense	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	organism	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	kappa	_	VERB	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	either	_	CCONJ	_	_	_	_	_	_
3	serine	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	32	_	NUM	_	NumType=Card	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	serine	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	36	_	NUM	_	NumType=Card	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	kappa	_	VERB	_	Number=Sing	_	_	_	_
13	B	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	mutated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	undergo	_	VERB	_	VerbForm=Inf	_	_	_	_
24	signal	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	degradation	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappa	_	PROPN	_	Number=Sing	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	could	_	AUX	_	VerbForm=Fin	_	_	_	_
37	not	_	PART	_	_	_	_	_	_
38	be	_	AUX	_	VerbForm=Inf	_	_	_	_
39	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	one	_	NUM	_	NumType=Card	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	both	_	DET	_	_	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	residues	_	NOUN	_	Number=Plur	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	critical	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	PROPN	_	Number=Sing	_	_	_	_
21	B.	_	PROPN	_	Number=Sing	_	_	_	_
22	Document	_	NOUN	_	Number=Sing	_	_	_	_
23	003001426	_	NUM	_	NumType=Card	_	_	_	_
24	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	TAR	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	independent	_	ADJ	_	Degree=Pos	_	_	_	_
4	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	Tat	_	PROPN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	CNS	_	NOUN	_	Number=Sing	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	novel	_	NOUN	_	Number=Sing	_	_	_	_
16	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	regulation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Tat	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	essential	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	productive	_	ADJ	_	Degree=Pos	_	_	_	_
19	infection	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	potential	_	ADJ	_	Degree=Pos	_	_	_	_
24	target	_	NOUN	_	Number=Sing	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	antiviral	_	ADJ	_	Degree=Pos	_	_	_	_
27	therapy	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Tat	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	potent	_	ADJ	_	Degree=Pos	_	_	_	_
5	activator	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	serves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	greatly	_	ADV	_	_	_	_	_	_
16	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	rate	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	viral	_	ADJ	_	Degree=Pos	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	component	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	progression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	acquired	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	immune	_	ADJ	_	Number=Sing	_	_	_	_
17	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
18	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	may	_	AUX	_	VerbForm=Fin	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	due	_	ADP	_	_	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	initiation	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
33	elongation	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	combination	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
40	processes	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Much	_	ADJ	_	Degree=Pos	_	_	_	_
2	attention	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	focused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	interaction	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Tat	_	PROPN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	RNA	_	PROPN	_	Number=Sing	_	_	_	_
15	target	_	NOUN	_	Number=Sing	_	_	_	_
16	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	TAR	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
20	responsive	_	ADJ	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	present	_	ADJ	_	Degree=Pos	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	leader	_	NOUN	_	Number=Sing	_	_	_	_
28	sequence	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	all	_	DET	_	_	_	_	_	_
31	HIV	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	interaction	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	important	_	ADJ	_	Degree=Pos	_	_	_	_
9	component	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	certain	_	ADJ	_	Degree=Pos	_	_	_	_
9	CNS	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_

1	Tat	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	capable	_	ADJ	_	Degree=Pos	_	_	_	_
4	of	_	SCONJ	_	_	_	_	_	_
5	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	TAR	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	independent	_	ADJ	_	Degree=Pos	_	_	_	_
14	pathway	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	Tat	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
5	element	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
9	within	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	viral	_	ADJ	_	Degree=Pos	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	glial	_	ADJ	_	Degree=Pos	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	allows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	absence	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	TAR	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	mapping	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	constructs	_	NOUN	_	Number=Plur	_	_	_	_
7	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	newly	_	ADV	_	_	_	_	_	_
11	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	Tat	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
15	element	_	NOUN	_	Number=Sing	_	_	_	_
16	corresponds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	sequence	_	NOUN	_	Number=Sing	_	_	_	_
20	within	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	viral	_	ADJ	_	Degree=Pos	_	_	_	_
23	long	_	ADJ	_	Degree=Pos	_	_	_	_
24	terminal	_	NOUN	_	Number=Sing	_	_	_	_
25	repeat	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	LTR	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	previously	_	ADV	_	_	_	_	_	_
30	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	as	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	HIV	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappa	_	PROPN	_	Number=Sing	_	_	_	_
42	B	_	PROPN	_	Number=Sing	_	_	_	_
43	domain	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	band	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	reveals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	glial	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	differs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	present	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	observe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	TAR	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	mutants	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	normal	_	ADJ	_	Degree=Pos	_	_	_	_
16	late	_	ADJ	_	Degree=Pos	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	glial	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	as	_	SCONJ	_	_	_	_	_	_
23	evidenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	syncytia	_	ADJ	_	Number=Sing	_	_	_	_
26	formation	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	production	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	viral	_	ADJ	_	Degree=Pos	_	_	_	_
31	p24	_	NOUN	_	Number=Sing	_	_	_	_
32	antigen	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	003001427	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
2	control	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	complex	_	NOUN	_	Number=Sing	_	_	_	_
16	:	_	PUNCT	_	_	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	tumor	_	NOUN	_	Number=Sing	_	_	_	_
20	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	TcR	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	CD3	_	PROPN	_	Number=Sing	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	primary	_	ADJ	_	Degree=Pos	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
31	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	at	_	ADP	_	_	_	_	_	_
33	various	_	ADJ	_	Degree=Pos	_	_	_	_
34	times	_	NOUN	_	Number=Plur	_	_	_	_
35	after	_	ADP	_	_	_	_	_	_
36	activation	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Only	_	ADV	_	_	_	_	_	_
2	p50	_	NUM	_	NumType=Card	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_
6	B	_	PROPN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	bound	_	VERB	_	Number=Sing	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2R	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	chain	_	NOUN	_	Number=Sing	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	on	_	SCONJ	_	_	_	_	_	_
27	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	immediately	_	ADV	_	_	_	_	_	_
4	after	_	ADP	_	_	_	_	_	_
5	TcR	_	PROPN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	CD3	_	PROPN	_	Number=Sing	_	_	_	_
8	cross	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	linking	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	approximately	_	ADV	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	h	_	NOUN	_	NumType=Card	_	_	_	_
16	;	_	PUNCT	_	_	_	_	_	_
17	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	p50.p65	_	NOUN	_	NumType=Card	_	_	_	_
22	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	p50.c	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	rel	_	NOUN	_	Number=Sing	_	_	_	_
4	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	bound	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	early	_	ADJ	_	Degree=Pos	_	_	_	_
14	time	_	NOUN	_	Number=Sing	_	_	_	_
15	points	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	7	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	SYM	_	_	_	_	_	_
19	16	_	NUM	_	NumType=Card	_	_	_	_
20	h	_	NOUN	_	Number=Plur	_	_	_	_
21	;	_	PUNCT	_	_	_	_	_	_
22	early	_	ADV	_	Degree=Pos	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	both	_	DET	_	_	_	_	_	_
27	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	active	_	ADJ	_	Degree=Pos	_	_	_	_
29	at	_	ADP	_	_	_	_	_	_
30	later	_	ADJ	_	Degree=Cmp	_	_	_	_
31	time	_	NOUN	_	Number=Sing	_	_	_	_
32	points	_	NOUN	_	Number=Plur	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	40	_	NUM	_	NumType=Card	_	_	_	_
35	h	_	NOUN	_	Number=Plur	_	_	_	_
36	;	_	PUNCT	_	_	_	_	_	_
37	late	_	ADJ	_	Degree=Pos	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	after	_	ADP	_	_	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	takes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	place	_	NOUN	_	Number=Sing	_	_	_	_
5	mainly	_	ADV	_	_	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	level	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	translocation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	p65	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	early	_	ADJ	_	Degree=Pos	_	_	_	_
21	time	_	NOUN	_	Number=Sing	_	_	_	_
22	points	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	p105	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	p50	_	NUM	_	NumType=Card	_	_	_	_
9	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
10	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	p65	_	NUM	_	Number=Sing	_	_	_	_
15	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
16	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	all	_	DET	_	_	_	_	_	_
4	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	early	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	late	_	ADJ	_	Degree=Pos	_	_	_	_
8	events	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	not	_	ADV	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
14	ones	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	neutralizing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	anti-tumor	_	ADJ	_	Degree=Pos	_	_	_	_
22	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	TNF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
31	antibody	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Similarly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
4	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	p65	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
9	translocation	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	consequent	_	ADJ	_	Degree=Pos	_	_	_	_
12	formation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	active	_	ADJ	_	Degree=Pos	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	early	_	ADJ	_	Degree=Pos	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	late	_	ADJ	_	Degree=Pos	_	_	_	_
22	times	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Cyclosporin	_	PROPN	_	Number=Sing	_	_	_	_
2	A	_	DET	_	Number=Sing	_	_	_	_
3	impaired	_	VERB	_	Degree=Pos	_	_	_	_
4	not	_	ADV	_	_	_	_	_	_
5	only	_	ADV	_	_	_	_	_	_
6	early	_	ADV	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	late	_	ADJ	_	Degree=Pos	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
13	events	_	NOUN	_	Number=Plur	_	_	_	_
14	;	_	PUNCT	_	_	_	_	_	_
15	however	_	ADV	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	addition	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	TNF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	prevented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	all	_	DET	_	_	_	_	_	_
24	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	during	_	ADP	_	_	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	TcR	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	CD3	_	PROPN	_	Number=Sing	_	_	_	_
21	signals	_	NOUN	_	Number=Plur	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	biphasic	_	ADJ	_	Number=Sing	_	_	_	_
24	:	_	PUNCT	_	_	_	_	_	_

1	TcR	_	PROPN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	CD3	_	PROPN	_	Number=Sing	_	_	_	_
4	triggers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
6	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
7	translocation	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	transient	_	ADJ	_	Degree=Pos	_	_	_	_
12	if	_	SCONJ	_	_	_	_	_	_
13	no	_	DET	_	_	_	_	_	_
14	TNF	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	present	_	ADJ	_	Degree=Pos	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	therefore	_	ADV	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	emerges	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	main	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
16	phase	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	regulation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
25	both	_	CCONJ	_	_	_	_	_	_
26	translocation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	p65	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	new	_	ADJ	_	Degree=Pos	_	_	_	_
34	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
35	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	p105	_	NOUN	_	Number=Sing	_	_	_	_
40	/	_	PUNCT	_	_	_	_	_	_
41	p50	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001429	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	ATF1	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	CREB	_	PROPN	_	Number=Sing	_	_	_	_
4	trans	_	NOUN	_	Number=Plur	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activate	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	cycle	_	NOUN	_	Number=Sing	_	_	_	_
10	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	histone	_	NOUN	_	Number=Sing	_	_	_	_
12	H4	_	NUM	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	distal	_	ADJ	_	Degree=Pos	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	matrix	_	NOUN	_	Number=Sing	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	element	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Proteins	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	ATF	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	CREB	_	NOUN	_	Number=Sing	_	_	_	_
7	class	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	stimulate	_	VERB	_	Degree=Pos	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	several	_	ADJ	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	growth	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	related	_	ADJ	_	Degree=Pos	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	through	_	ADP	_	_	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	A	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	related	_	ADJ	_	Degree=Pos	_	_	_	_
27	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
28	response	_	NOUN	_	Number=Sing	_	_	_	_
29	elements	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	promoter	_	ADJ	_	Degree=Pos	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	cycle	_	NOUN	_	Number=Sing	_	_	_	_
7	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	histone	_	NOUN	_	Number=Sing	_	_	_	_
9	H4	_	NUM	_	Number=Sing	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	at	_	ADV	_	_	_	_	_	_
15	least	_	ADV	_	Degree=Sup	_	_	_	_
16	four	_	NUM	_	NumType=Card	_	_	_	_
17	principal	_	ADJ	_	Degree=Pos	_	_	_	_
18	cis	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	acting	_	VERB	_	Number=Sing	_	_	_	_
21	elements	_	NOUN	_	Number=Plur	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	G1	_	PROPN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	S	_	PROPN	_	Number=Sing	_	_	_	_
27	phase	_	NOUN	_	Number=Sing	_	_	_	_
28	control	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	during	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	cycle	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	protein-DNA	_	NOUN	_	Number=Sing	_	_	_	_
3	interaction	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	H4	_	PROPN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	two	_	NUM	_	NumType=Card	_	_	_	_
13	ATF	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	CREB	_	VERB	_	Number=Sing	_	_	_	_
16	recognition	_	NOUN	_	Number=Sing	_	_	_	_
17	motifs	_	VERB	_	Number=Plur	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	CREB	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	ATF1	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	ATF2	_	NOUN	_	Number=Sing	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	not	_	ADV	_	_	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	ATF4	_	NOUN	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	CREB2	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	ATF	_	NOUN	_	Number=Sing	_	_	_	_
3	/	_	PUNCT	_	_	_	_	_	_
4	CRE	_	PROPN	_	Number=Sing	_	_	_	_
5	motif	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	distal	_	ADJ	_	Degree=Pos	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	matrix	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	Site	_	NOUN	_	Number=Sing	_	_	_	_
19	IV	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
24	motif	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	present	_	ADJ	_	Degree=Pos	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	at	_	ADP	_	_	_	_	_	_
32	Site	_	NOUN	_	Number=Sing	_	_	_	_
33	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	ATF	_	NOUN	_	Number=Sing	_	_	_	_
3	/	_	PUNCT	_	_	_	_	_	_
4	CRE	_	NOUN	_	Number=Sing	_	_	_	_
5	motifs	_	NOUN	_	Number=Plur	_	_	_	_
6	overlap	_	VERB	_	Degree=Pos	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	sequences	_	NOUN	_	Number=Plur	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	multifunctional	_	ADJ	_	Degree=Pos	_	_	_	_
12	YY1	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	previously	_	ADV	_	_	_	_	_	_
19	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
20	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	matrix	_	NOUN	_	Number=Sing	_	_	_	_
25	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Subnuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	fractionation	_	NOUN	_	Number=Sing	_	_	_	_
3	reveals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	there	_	PRON	_	_	_	_	_	_
6	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	ATF1	_	NOUN	_	Degree=Pos	_	_	_	_
9	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	differ	_	VERB	_	VerbForm=Inf	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	respect	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	DNA	_	NOUN	_	Number=Sing	_	_	_	_
18	binding	_	VERB	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	partition	_	NOUN	_	Number=Sing	_	_	_	_
22	selectively	_	ADV	_	_	_	_	_	_
23	between	_	ADP	_	_	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	matrix	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	nonmatrix	_	ADJ	_	Degree=Pos	_	_	_	_
28	compartments	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	role	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
37	matrix	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	SCONJ	_	_	_	_	_	_
39	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Site	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	mutational	_	ADJ	_	Degree=Pos	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	Site	_	NOUN	_	Number=Sing	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	Site	_	PROPN	_	Number=Sing	_	_	_	_
12	IV	_	NOUN	_	Number=Sing	_	_	_	_
13	together	_	ADV	_	_	_	_	_	_
14	support	_	VERB	_	VerbForm=Inf	_	_	_	_
15	ATF1	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	CREB	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	trans	_	NOUN	_	Number=Plur	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	H4	_	NOUN	_	Number=Sing	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	establish	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	ATF	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	CREB	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	functionally	_	ADV	_	_	_	_	_	_
12	modulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	histone	_	NOUN	_	Number=Sing	_	_	_	_
14	H4	_	NUM	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	distal	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	elements	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001432	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	post	_	X	_	_	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	jun	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	during	_	ADP	_	_	_	_	_	_
13	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
18	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	AP	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	polypeptide	_	NOUN	_	Degree=Pos	_	_	_	_
7	product	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	c	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	jun	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	recognizes	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	binds	_	NOUN	_	Number=Plur	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	DNA	_	NOUN	_	Number=Sing	_	_	_	_
19	sequences	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	stimulates	_	VERB	_	Degree=Pos	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	certain	_	ADJ	_	Degree=Pos	_	_	_	_
28	growth	_	NOUN	_	Number=Sing	_	_	_	_
29	factors	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
32	esters	_	NOUN	_	Number=Plur	_	_	_	_
33	such	_	ADJ	_	Degree=Pos	_	_	_	_
34	as	_	ADP	_	_	_	_	_	_
35	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	13	_	NUM	_	NumType=Card	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	acetate	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	TPA	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	TPA	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	regulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	c	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	jun	_	NOUN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	HL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	60	_	NUM	_	NumType=Card	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	during	_	ADP	_	_	_	_	_	_
22	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Low	_	ADJ	_	Degree=Pos	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	jun	_	NOUN	_	Number=Sing	_	_	_	_
7	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
12	HL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	60	_	NUM	_	NumType=Card	_	_	_	_
15	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	significantly	_	ADV	_	_	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	6	_	NUM	_	NumType=Card	_	_	_	_
22	h	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	reached	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	near	_	ADP	_	_	_	_	_	_
27	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
28	levels	_	NOUN	_	Number=Plur	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	24	_	NUM	_	NumType=Card	_	_	_	_
31	h	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	exposure	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	32	_	NUM	_	NumType=Card	_	_	_	_
36	nM	_	NOUN	_	Number=Sing	_	_	_	_
37	TPA	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	jun	_	NOUN	_	Number=Sing	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	TPA	_	PROPN	_	Number=Sing	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	U	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	937	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	THP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	bryostatin	_	NOUN	_	Number=Sing	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	nM	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	another	_	DET	_	_	_	_	_	_
14	activator	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	C	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	inducer	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	1,25	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
6	D3	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	0.5	_	NUM	_	NumType=Card	_	_	_	_
9	microM	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	structurally	_	ADV	_	_	_	_	_	_
14	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
15	agent	_	NOUN	_	Number=Sing	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	also	_	ADV	_	_	_	_	_	_
18	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	HL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	60	_	NUM	_	NumType=Card	_	_	_	_
22	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	c	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	jun	_	NOUN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	TPA	_	PROPN	_	Number=Sing	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	60	_	NUM	_	NumType=Card	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	presence	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	superinduction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	c	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	jun	_	NOUN	_	Number=Sing	_	_	_	_
21	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Run	_	VERB	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	c	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	jun	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
16	HL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	60	_	NUM	_	NumType=Card	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	exposure	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	TPA	_	PROPN	_	Number=Sing	_	_	_	_
26	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	rate	_	NOUN	_	Number=Sing	_	_	_	_
29	3.3	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	fold	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	60	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	TPA	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
12	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	no	_	DET	_	_	_	_	_	_
14	effect	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	rates	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	c	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	jun	_	NOUN	_	Number=Sing	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	half	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	life	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	c	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	jun	_	NOUN	_	Number=Sing	_	_	_	_
9	RNA	_	PROPN	_	Number=Sing	_	_	_	_
10	as	_	SCONJ	_	_	_	_	_	_
11	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	treating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	HL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	60	_	NUM	_	NumType=Card	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	TPA	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	actinomycin	_	PROPN	_	Number=Sing	_	_	_	_
22	D	_	PROPN	_	Number=Sing	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	30	_	NUM	_	NumType=Card	_	_	_	_
25	min	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	half	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	life	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	c	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	jun	_	NOUN	_	Number=Sing	_	_	_	_
12	RNA	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	TPA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	HL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	60	_	NUM	_	NumType=Card	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	actinomycin	_	NOUN	_	Number=Sing	_	_	_	_
26	D	_	PROPN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
29	than	_	ADP	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	h	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	increase	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
9	RNA	_	PROPN	_	Number=Sing	_	_	_	_
10	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	TPA	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	post	_	NOUN	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
26	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001433	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	differentiated	_	ADJ	_	Degree=Pos	_	_	_	_
9	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	like	_	ADP	_	_	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	U937	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	AP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
25	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	beta	_	NOUN	_	Number=Sing	_	_	_	_
28	site	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	distal	_	ADJ	_	Degree=Pos	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	element	_	NOUN	_	Number=Sing	_	_	_	_
18	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	induction	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	during	_	ADP	_	_	_	_	_	_
26	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
27	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Chloramphenicol	_	PROPN	_	Number=Sing	_	_	_	_
2	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	constructs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	regions	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	stably	_	ADJ	_	Degree=Pos	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	transiently	_	ADV	_	_	_	_	_	_
18	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	into	_	ADP	_	_	_	_	_	_
20	U937	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	reporter	_	NOUN	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	at	_	ADP	_	_	_	_	_	_
29	various	_	ADJ	_	Degree=Pos	_	_	_	_
30	times	_	NOUN	_	Number=Plur	_	_	_	_
31	after	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	onset	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
36	12	_	NUM	_	NumType=Card	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	myristate	_	NOUN	_	Number=Sing	_	_	_	_
39	13	_	NUM	_	NumType=Card	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	acetate	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	PMA	_	PROPN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
47	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Rapid	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	strong	_	ADJ	_	Degree=Pos	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	lost	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	constructs	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	mutant	_	ADJ	_	Number=Sing	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	element	_	NOUN	_	Number=Sing	_	_	_	_
19	;	_	PUNCT	_	_	_	_	_	_
20	however	_	ADV	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	at	_	ADP	_	_	_	_	_	_
23	16	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	SYM	_	_	_	_	_	_
25	96	_	NUM	_	NumType=Card	_	_	_	_
26	h	_	NUM	_	Number=Sing	_	_	_	_
27	post-PMA	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	mutant	_	ADJ	_	Number=Sing	_	_	_	_
31	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	displayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	AP	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	independent	_	ADJ	_	Degree=Pos	_	_	_	_
40	PMA	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
43	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	AP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	mutant	_	NOUN	_	Number=Sing	_	_	_	_
6	constructs	_	NOUN	_	Number=Plur	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	PMA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	supershift	_	NOUN	_	Number=Sing	_	_	_	_
4	analyses	_	NOUN	_	Number=Plur	_	_	_	_
5	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	functional	_	ADJ	_	Degree=Pos	_	_	_	_
8	Jun	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	Fos	_	PROPN	_	Number=Sing	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	present	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	extracts	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	PMA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
21	U937	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Promoter	_	NOUN	_	Number=Sing	_	_	_	_
2	deletion	_	NOUN	_	Number=Sing	_	_	_	_
3	constructs	_	NOUN	_	Number=Plur	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	potential	_	ADJ	_	Degree=Pos	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	distal	_	ADJ	_	Degree=Pos	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	sequences	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	SCONJ	_	_	_	_	_	_
13	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	particular	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	Western	_	ADJ	_	Degree=Pos	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	supershift	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	deletion	_	NOUN	_	Number=Sing	_	_	_	_
11	analyses	_	NOUN	_	Number=Plur	_	_	_	_
12	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	role	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	CCAAT	_	PROPN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	beta	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	beta	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	binding	_	NOUN	_	VerbForm=Ger	_	_	_	_
30	site	_	NOUN	_	Number=Sing	_	_	_	_
31	between	_	ADP	_	_	_	_	_	_
32	-	_	SYM	_	_	_	_	_	_
33	2010	_	NUM	_	NumType=Card	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	-	_	SYM	_	_	_	_	_	_
36	1954	_	NUM	_	NumType=Card	_	_	_	_
37	in	_	SCONJ	_	_	_	_	_	_
38	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	1	_	NUM	_	NumType=Card	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
5	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	elements	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
10	somewhat	_	ADV	_	_	_	_	_	_
11	independently	_	ADV	_	_	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	each	_	DET	_	_	_	_	_	_
14	other	_	ADJ	_	Degree=Pos	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	control	_	VERB	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
10	PMA	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	collagenase	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
24	distinct	_	NOUN	_	Number=Sing	_	_	_	_
25	from	_	SCONJ	_	_	_	_	_	_
26	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
27	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	proteinase	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001436	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cloning	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	DNA	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	binding	_	VERB	_	Number=Sing	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	homology	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	rel	_	NOUN	_	Number=Sing	_	_	_	_
21	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	cycle	_	NOUN	_	Number=Sing	_	_	_	_
27	motifs	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	mitogen	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	predicts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	968	_	NUM	_	NumType=Card	_	_	_	_
22	amino	_	NOUN	_	Number=Sing	_	_	_	_
23	acids	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	amino	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	terminal	_	NOUN	_	Number=Sing	_	_	_	_
5	domain	_	NOUN	_	Number=Sing	_	_	_	_
6	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	regions	_	NOUN	_	Number=Plur	_	_	_	_
8	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
12	rel	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	developmentally	_	ADV	_	_	_	_	_	_
17	important	_	ADJ	_	Degree=Pos	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	dorsal	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	Drosophila	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	carboxy	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	terminal	_	NOUN	_	Number=Sing	_	_	_	_
5	domain	_	NOUN	_	Number=Sing	_	_	_	_
6	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	repeat	_	ADJ	_	Degree=Pos	_	_	_	_
8	structures	_	NOUN	_	Number=Plur	_	_	_	_
9	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	variety	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	involved	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	cycle	_	NOUN	_	Number=Sing	_	_	_	_
22	control	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	yeast	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	tissue	_	NOUN	_	Number=Sing	_	_	_	_
28	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	Drosophila	_	PROPN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	Ceanorhabditis	_	PROPN	_	Number=Sing	_	_	_	_
33	elegans	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	as	_	ADV	_	_	_	_	_	_
36	well	_	ADV	_	Degree=Pos	_	_	_	_
37	as	_	ADP	_	_	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	putative	_	ADJ	_	Degree=Pos	_	_	_	_
41	human	_	ADJ	_	Degree=Pos	_	_	_	_
42	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
43	bcl	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	3	_	NUM	_	NumType=Card	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	ankyrin	_	NOUN	_	Number=Sing	_	_	_	_
50	protein	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	truncated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
3	form	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	product	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	vitro	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	DNA	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	specifically	_	ADV	_	_	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	site	_	NOUN	_	Number=Sing	_	_	_	_
28	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	many	_	ADJ	_	Degree=Pos	_	_	_	_
31	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	including	_	VERB	_	VerbForm=Ger	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	human	_	ADJ	_	Degree=Pos	_	_	_	_
39	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
40	virus	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	yet	_	ADV	_	_	_	_	_	_
5	another	_	DET	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	growing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	list	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	important	_	ADJ	_	Degree=Pos	_	_	_	_
12	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	molecules	_	NOUN	_	Number=Plur	_	_	_	_
14	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	transcriptionally	_	ADV	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	upon	_	ADP	_	_	_	_	_	_
20	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001437	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	Rel	_	PROPN	_	Number=Sing	_	_	_	_
4	family	_	NOUN	_	Number=Sing	_	_	_	_
5	members	_	NOUN	_	Number=Plur	_	_	_	_
6	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
14	THP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	kappa	_	NOUN	_	Number=Sing	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
14	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
15	molecule	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	involved	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	regulation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	tumor	_	NOUN	_	Number=Sing	_	_	_	_
37	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
38	factor	_	NOUN	_	Number=Sing	_	_	_	_
39	alpha	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	TNF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	alpha	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	transactivate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
14	RelA	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	c-Rel	_	NOUN	_	Degree=Pos	_	_	_	_
17	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
18	as	_	ADV	_	_	_	_	_	_
19	well	_	ADV	_	Degree=Pos	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B1	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	but	_	CCONJ	_	_	_	_	_	_
29	weakly	_	ADV	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B1	_	NOUN	_	Number=Sing	_	_	_	_
34	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	RelA	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	PROPN	_	Number=Sing	_	_	_	_
14	B1	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	reporter	_	NOUN	_	Number=Sing	_	_	_	_
28	construct	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
3	THP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	two	_	NUM	_	NumType=Card	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	complexes	_	NOUN	_	Number=Plur	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	vitro	_	NOUN	_	Number=Sing	_	_	_	_
17	bound	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
6	mobility	_	NOUN	_	Number=Sing	_	_	_	_
7	supershift	_	NOUN	_	Number=Sing	_	_	_	_
8	assay	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	one	_	NUM	_	NumType=Card	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	complexes	_	NOUN	_	Number=Plur	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B1	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	RelA	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
30	affinity	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	consensus	_	NOUN	_	Number=Sing	_	_	_	_
34	kappa	_	NOUN	_	Number=Sing	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	site	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	HIV	_	PROPN	_	Number=Sing	_	_	_	_
40	long	_	ADJ	_	Degree=Pos	_	_	_	_
41	terminal	_	NOUN	_	Number=Sing	_	_	_	_
42	repeat	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	complex	_	NOUN	_	Number=Sing	_	_	_	_
4	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	RelA	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	exhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
10	affinity	_	NOUN	_	Number=Sing	_	_	_	_
11	towards	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	HIV	_	PROPN	_	Number=Sing	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	repress	_	VERB	_	VerbForm=Inf	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	RelA	_	PROPN	_	Number=Sing	_	_	_	_
13	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B1	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	RelA	_	PROPN	_	Number=Sing	_	_	_	_
22	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	argue	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	vivo	_	PROPN	_	Degree=Pos	_	_	_	_
6	RelA	_	PROPN	_	Number=Sing	_	_	_	_
7	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	likely	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	play	_	VERB	_	VerbForm=Inf	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
14	role	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001441	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activity	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	kappa	_	PROPN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	chain	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	somatic	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	hybrids	_	NOUN	_	Number=Plur	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	localization	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	PROPN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	proteins	_	NOUN	_	Number=Plur	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	consisting	_	VERB	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	subunits	_	NOUN	_	Number=Plur	_	_	_	_
13	p50	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	p65	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	DNA	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	binding	_	VERB	_	Number=Sing	_	_	_	_
22	subunit	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	p50	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	itself	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs|Reflex=Yes	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	also	_	ADV	_	_	_	_	_	_
35	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	KBF1	_	PROPN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	constitutively	_	ADV	_	_	_	_	_	_
40	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	localized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	human	_	ADJ	_	Degree=Pos	_	_	_	_
49	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
50	line	_	NOUN	_	Number=Sing	_	_	_	_
51	IARC	_	PROPN	_	Number=Sing	_	_	_	_
52	301.5	_	NUM	_	NumType=Card	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	define	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	roles	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	same	_	ADJ	_	Degree=Pos	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
25	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	somatic	_	ADJ	_	Degree=Pos	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	hybrids	_	NOUN	_	Number=Plur	_	_	_	_
30	between	_	ADP	_	_	_	_	_	_
31	IARC	_	PROPN	_	Number=Sing	_	_	_	_
32	301.5	_	NUM	_	NumType=Card	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	murine	_	NOUN	_	Number=Sing	_	_	_	_
36	myeloma	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Most	_	ADJ	_	Degree=Sup	_	_	_	_
2	hybrids	_	NOUN	_	Number=Plur	_	_	_	_
3	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	KBF1	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	one	_	NUM	_	NumType=Card	_	_	_	_
17	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
18	expresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	only	_	ADV	_	_	_	_	_	_
20	KBF1	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	kappa	_	NOUN	_	Number=Sing	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	alpha	_	PROPN	_	Number=Sing	_	_	_	_
20	chain	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2R	_	NUM	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	functional	_	ADJ	_	Degree=Pos	_	_	_	_
29	only	_	ADV	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	hybrids	_	NOUN	_	Number=Plur	_	_	_	_
33	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
34	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	while	_	SCONJ	_	_	_	_	_	_
20	KBF1	_	PROPN	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	itself	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs|Reflex=Yes	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	KBF1	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	competitive	_	ADJ	_	Degree=Pos	_	_	_	_
8	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	PROPN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	discuss	_	VERB	_	VerbForm=Inf	_	_	_	_
16	how	_	ADV	_	PronType=Int	_	_	_	_
17	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	may	_	AUX	_	VerbForm=Fin	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	involved	_	ADJ	_	Degree=Pos	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	transient	_	ADJ	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2R	_	PROPN	_	NumType=Card	_	_	_	_
34	alpha	_	NOUN	_	Number=Sing	_	_	_	_
35	genes	_	NOUN	_	Number=Plur	_	_	_	_
36	during	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	immune	_	ADJ	_	Degree=Pos	_	_	_	_
39	response	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001444	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	proto	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	oncogenes	_	NOUN	_	Number=Sing	_	_	_	_
7	c	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	jun	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	c	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	fos	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	CD28	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	surface	_	NOUN	_	Number=Sing	_	_	_	_
5	molecule	_	NOUN	_	Number=Sing	_	_	_	_
6	CD28	_	NOUN	_	Number=Sing	_	_	_	_
7	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	ligands	_	NOUN	_	Number=Plur	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	accessory	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	APCs	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	playing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	important	_	ADJ	_	Degree=Pos	_	_	_	_
19	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
20	role	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	T	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	Ags	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	knowledge	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
6	signaling	_	NOUN	_	Number=Sing	_	_	_	_
7	pathways	_	NOUN	_	Number=Plur	_	_	_	_
8	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	incomplete	_	ADJ	_	_	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	phospholipase	_	NOUN	_	Number=Sing	_	_	_	_
7	C	_	PROPN	_	Number=Sing	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	ligation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	calcium	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	independent	_	ADJ	_	Degree=Pos	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	CD28	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	pathway	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	paper	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	cross	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	linking	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	CD28	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	CD2	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	CD5	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	LFA	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	CD7	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	elevation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	c	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	jun	_	NOUN	_	Number=Sing	_	_	_	_
35	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	only	_	ADV	_	_	_	_	_	_
39	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	c	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	fos	_	ADP	_	Number=Sing	_	_	_	_
45	expression	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	CD28	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	c	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	jun	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	depend	_	VERB	_	VerbForm=Inf	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
25	ester	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	kinase	_	NOUN	_	Number=Sing	_	_	_	_
30	C	_	NOUN	_	Number=Sing	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	elevation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
35	calcium	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CD28	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
6	elevation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	jun	_	NOUN	_	Number=Sing	_	_	_	_
11	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
12	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	appear	_	VERB	_	VerbForm=Inf	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
23	stability	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	whereby	_	ADV	_	_	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	jun	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	junB	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	absence	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	members	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	fos	_	NOUN	_	Number=Sing	_	_	_	_
22	family	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	can	_	AUX	_	VerbForm=Fin	_	_	_	_
25	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
26	inappropriate	_	ADJ	_	Degree=Pos	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	T	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	ligation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	CD28	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	absence	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	specific	_	ADJ	_	Degree=Pos	_	_	_	_
42	antigenic	_	ADJ	_	Degree=Pos	_	_	_	_
43	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001449	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
2	inhibit	_	VERB	_	Number=Sing	_	_	_	_
3	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
4	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	SCONJ	_	_	_	_	_	_
6	suppressing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
19	molecule	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	generate	_	VERB	_	VerbForm=Inf	_	_	_	_
28	radicals	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	tumor	_	NOUN	_	Number=Sing	_	_	_	_
9	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	due	_	ADP	_	_	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	surface	_	NOUN	_	Number=Sing	_	_	_	_
22	receptors	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	such	_	ADJ	_	Degree=Pos	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
29	molecule	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	antioxidant	_	NOUN	_	Degree=Pos	_	_	_	_
3	pyrrolidine	_	NOUN	_	Number=Sing	_	_	_	_
4	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	specifically	_	ADV	_	_	_	_	_	_
9	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	kappa	_	NOUN	_	Number=Sing	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	motifs	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	present	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
13	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
14	molecule	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	promoters	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
25	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	study	_	VERB	_	VerbForm=Inf	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	induction	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
43	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
44	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	TNF	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	human	_	ADJ	_	Degree=Pos	_	_	_	_
50	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
51	vein	_	NOUN	_	Number=Sing	_	_	_	_
52	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
53	cells	_	NOUN	_	Number=Plur	_	_	_	_
54	(	_	PUNCT	_	_	_	_	_	_
55	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
2	or	_	CCONJ	_	_	_	_	_	_
3	N	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	acetylcysteine	_	NOUN	_	Number=Sing	_	_	_	_
6	dose	_	NOUN	_	Number=Sing	_	_	_	_
7	dependently	_	ADV	_	_	_	_	_	_
8	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	TNF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	not	_	ADV	_	_	_	_	_	_
17	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	surface	_	NOUN	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	also	_	ADV	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
27	arterial	_	NOUN	_	Degree=Pos	_	_	_	_
28	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	70	_	NUM	_	NumType=Card	_	_	_	_
37	%	_	SYM	_	Number=Sing	_	_	_	_
38	at	_	ADP	_	_	_	_	_	_
39	100	_	NUM	_	NumType=Card	_	_	_	_
40	mumol	_	NOUN	_	Number=Sing	_	_	_	_
41	/	_	PUNCT	_	_	_	_	_	_
42	L	_	NOUN	_	Number=Sing	_	_	_	_
43	PDTC	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	HUVECs	_	NOUN	_	Number=Sing	_	_	_	_
47	as	_	SCONJ	_	_	_	_	_	_
48	assessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	by	_	ADP	_	_	_	_	_	_
50	flow	_	NOUN	_	Number=Sing	_	_	_	_
51	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
54	chain	_	NOUN	_	Number=Sing	_	_	_	_
55	reaction	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	HUVECs	_	PROPN	_	Number=Sing	_	_	_	_
7	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
10	prevented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	TNF	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	only	_	ADV	_	_	_	_	_	_
22	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	induction	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B.	_	PROPN	_	Number=Sing	_	_	_	_
33	Since	_	SCONJ	_	_	_	_	_	_
34	HUVECs	_	PROPN	_	Number=Sing	_	_	_	_
35	released	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	superoxide	_	NOUN	_	Number=Sing	_	_	_	_
37	anions	_	NOUN	_	Number=Plur	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	response	_	NOUN	_	Number=Sing	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	TNF	_	PROPN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	H2O2	_	PROPN	_	Number=Sing	_	_	_	_
45	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
46	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	1	_	NUM	_	NumType=Card	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
51	may	_	AUX	_	VerbForm=Fin	_	_	_	_
52	act	_	VERB	_	VerbForm=Inf	_	_	_	_
53	as	_	ADP	_	_	_	_	_	_
54	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
55	radical	_	ADJ	_	Degree=Pos	_	_	_	_
56	scavenger	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NADPH	_	PROPN	_	Number=Sing	_	_	_	_
12	oxidase	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	apocynin	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	cytochrome	_	NOUN	_	Number=Sing	_	_	_	_
18	P-450	_	PROPN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	SKF525a	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	induction	_	NOUN	_	Number=Sing	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	TNF	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	revealing	_	VERB	_	VerbForm=Ger	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	several	_	ADJ	_	Degree=Pos	_	_	_	_
33	radical	_	ADJ	_	Degree=Pos	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	generating	_	NOUN	_	Number=Sing	_	_	_	_
36	systems	_	NOUN	_	Number=Plur	_	_	_	_
37	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	involved	_	ADJ	_	Degree=Pos	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
41	regulation	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	apocynin	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	SKF525a	_	PROPN	_	Number=Sing	_	_	_	_
7	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	U937	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	75	_	NUM	_	NumType=Card	_	_	_	_
21	%	_	SYM	_	Number=Sing	_	_	_	_
22	at	_	ADP	_	_	_	_	_	_
23	100	_	NUM	_	NumType=Card	_	_	_	_
24	mumol	_	NOUN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	L	_	NOUN	_	Number=Sing	_	_	_	_
27	PDTC	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	anti-VCAM	_	ADJ	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	monoclonal	_	ADJ	_	Number=Sing	_	_	_	_
7	antibody	_	NOUN	_	Number=Sing	_	_	_	_
8	1G11	_	PROPN	_	Number=Sing	_	_	_	_
9	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	U937	_	PROPN	_	Number=Sing	_	_	_	_
12	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	VCAM	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	suppression	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	due	_	ADP	_	_	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	induction	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	003001450	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Reduction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	tumour	_	NOUN	_	Degree=Pos	_	_	_	_
4	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	signalling	_	VERB	_	VerbForm=Ger	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
12	blood	_	NOUN	_	Number=Sing	_	_	_	_
13	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	patients	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	thalassaemia	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	sickle	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	anaemia	_	NOUN	_	Number=Sing	_	_	_	_
23	upon	_	ADP	_	_	_	_	_	_
24	treatment	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	desferrioxamine	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	evidence	_	NOUN	_	Number=Sing	_	_	_	_
3	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	rate	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	progression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	disease	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	significantly	_	ADV	_	_	_	_	_	_
17	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	thalassaemia	_	PROPN	_	Number=Sing	_	_	_	_
20	major	_	ADJ	_	Degree=Pos	_	_	_	_
21	patients	_	NOUN	_	Number=Plur	_	_	_	_
22	upon	_	ADP	_	_	_	_	_	_
23	treatment	_	NOUN	_	Number=Sing	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	high	_	ADJ	_	Degree=Pos	_	_	_	_
26	doses	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	desferrioxamine	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	DFX	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	authors	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	previously	_	ADV	_	_	_	_	_	_
5	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	vitro	_	ADJ	_	Degree=Pos	_	_	_	_
9	exposure	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	DFX	_	PROPN	_	Number=Sing	_	_	_	_
15	decreases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	bioavailability	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	tumour	_	NOUN	_	Number=Sing	_	_	_	_
20	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	TNF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
32	effect	_	NOUN	_	Number=Sing	_	_	_	_
33	on	_	ADP	_	_	_	_	_	_
34	HIV	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	replication	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	therefore	_	ADV	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	bioavailability	_	NOUN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	10	_	NUM	_	NumType=Card	_	_	_	_
17	patients	_	NOUN	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	thalassaemia	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	sickle	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	anaemia	_	NOUN	_	Number=Sing	_	_	_	_
24	given	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	DFX	_	NOUN	_	Number=Sing	_	_	_	_
26	as	_	SCONJ	_	_	_	_	_	_
27	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	10	_	NUM	_	NumType=Card	_	_	_	_
30	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
31	subjects	_	NOUN	_	Number=Plur	_	_	_	_
32	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
34	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	presented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	showing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	DFX	_	PROPN	_	Number=Sing	_	_	_	_
7	treatment	_	NOUN	_	Number=Sing	_	_	_	_
8	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	TNF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	bioavailability	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	P<0.05	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	by	_	SCONJ	_	_	_	_	_	_
17	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	steady	_	ADJ	_	Degree=Pos	_	_	_	_
20	state	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	P<0.05	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	by	_	SCONJ	_	_	_	_	_	_
26	enhancing	_	VERB	_	VerbForm=Ger	_	_	_	_
27	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
29	through	_	ADP	_	_	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	soluble	_	ADJ	_	VerbForm=Inf	_	_	_	_
33	TNF	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	alpha	_	NOUN	_	Number=Sing	_	_	_	_
36	receptor	_	NOUN	_	Number=Sing	_	_	_	_
37	type	_	NOUN	_	Number=Sing	_	_	_	_
38	II	_	NUM	_	NumType=Card	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	P<0.05	_	NUM	_	NumType=Card	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	DFX	_	PROPN	_	Number=Sing	_	_	_	_
6	treatment	_	NOUN	_	Number=Sing	_	_	_	_
7	limits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vivo	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	TNF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	TNF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	signalling	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	P<0.005	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	bioavailability	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	signalling	_	NOUN	_	Number=Sing	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	impaired	_	VERB	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	patients	_	NOUN	_	Number=Sing	_	_	_	_
14	upon	_	ADP	_	_	_	_	_	_
15	DFX	_	NOUN	_	Number=Sing	_	_	_	_
16	treatment	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	may	_	AUX	_	VerbForm=Fin	_	_	_	_
4	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	delayed	_	VERB	_	Degree=Pos	_	_	_	_
7	progression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	infection	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	vivo	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1999	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001463	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Heterodimerization	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	vitro	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	family	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
12	DNA	_	NOUN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	rel	_	NOUN	_	Number=Sing	_	_	_	_
16	related	_	ADJ	_	Degree=Pos	_	_	_	_
17	polypeptides	_	NOUN	_	Number=Plur	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	contribute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	regulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	involved	_	ADJ	_	Degree=Pos	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	immune	_	ADJ	_	Degree=Pos	_	_	_	_
27	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	as	_	ADV	_	_	_	_	_	_
32	well	_	ADV	_	Degree=Pos	_	_	_	_
33	as	_	ADP	_	_	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	HIV	_	PROPN	_	Number=Sing	_	_	_	_
38	long	_	ADJ	_	Degree=Pos	_	_	_	_
39	terminal	_	NOUN	_	Number=Sing	_	_	_	_
40	repeat	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	related	_	ADJ	_	Degree=Pos	_	_	_	_
10	polypeptides	_	NOUN	_	Number=Plur	_	_	_	_
11	ranging	_	VERB	_	VerbForm=Ger	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	85	_	NUM	_	NumType=Card	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	45	_	NUM	_	NumType=Card	_	_	_	_
16	kDa	_	NOUN	_	Number=Sing	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	capacity	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	PRDII	_	PROPN	_	Number=Sing	_	_	_	_
27	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	element	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	interferon	_	NOUN	_	Number=Sing	_	_	_	_
31	beta	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	possess	_	VERB	_	VerbForm=Inf	_	_	_	_
37	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
38	intrinsic	_	ADJ	_	Degree=Pos	_	_	_	_
39	DNA	_	PROPN	_	Number=Sing	_	_	_	_
40	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
41	affinities	_	NOUN	_	Number=Plur	_	_	_	_
42	for	_	ADP	_	_	_	_	_	_
43	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
44	NF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	kappa	_	NOUN	_	Number=Sing	_	_	_	_
47	B	_	NOUN	_	Number=Sing	_	_	_	_
48	site	_	NOUN	_	Number=Sing	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	form	_	VERB	_	VerbForm=Inf	_	_	_	_
51	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
52	DNA	_	NOUN	_	Number=Sing	_	_	_	_
53	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
54	homo	_	NOUN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
58	complexes	_	NOUN	_	Number=Plur	_	_	_	_
59	in	_	ADP	_	_	_	_	_	_
60	co-renaturation	_	NOUN	_	Number=Sing	_	_	_	_
61	experiments	_	NOUN	_	Number=Plur	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	using	_	VERB	_	VerbForm=Ger	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	templates	_	NOUN	_	Number=Plur	_	_	_	_
6	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	copies	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	PRDII	_	PROPN	_	Number=Sing	_	_	_	_
12	domain	_	NOUN	_	Number=Sing	_	_	_	_
13	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	rabbit	_	NOUN	_	Number=Sing	_	_	_	_
17	beta	_	NOUN	_	Number=Sing	_	_	_	_
18	globin	_	NOUN	_	Degree=Pos	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	purified	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
23	polypeptides	_	NOUN	_	Number=Plur	_	_	_	_
24	specifically	_	ADV	_	_	_	_	_	_
25	stimulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	vitro	_	ADJ	_	Number=Sing	_	_	_	_
36	reconstitution	_	NOUN	_	Number=Sing	_	_	_	_
37	assay	_	NOUN	_	Number=Sing	_	_	_	_
38	as	_	ADP	_	_	_	_	_	_
39	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
40	but	_	CCONJ	_	_	_	_	_	_
41	not	_	ADV	_	_	_	_	_	_
42	as	_	ADP	_	_	_	_	_	_
43	p50	_	NUM	_	Number=Sing	_	_	_	_
44	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	emphasize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	dimerization	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	control	_	NOUN	_	Number=Sing	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	permit	_	VERB	_	VerbForm=Inf	_	_	_	_
22	functional	_	ADJ	_	Degree=Pos	_	_	_	_
23	diversification	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	limited	_	ADJ	_	Degree=Pos	_	_	_	_
27	number	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001467	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	GM2	_	PROPN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	GM	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	CSF	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	essential	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	induction	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	responses	_	NOUN	_	Number=Plur	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	:	_	PUNCT	_	_	_	_	_	_
29	purification	_	NOUN	_	Number=Sing	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
33	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
34	line	_	NOUN	_	Number=Sing	_	_	_	_
35	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	similarity	_	NOUN	_	Number=Sing	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappa	_	PROPN	_	Number=Sing	_	_	_	_
43	B.	_	PROPN	_	Number=Sing	_	_	_	_
44	Activation	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	T	_	PROPN	_	Number=Sing	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	by	_	ADP	_	_	_	_	_	_
49	antigen	_	NOUN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	lectin	_	NOUN	_	Number=Sing	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	or	_	CCONJ	_	_	_	_	_	_
54	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
55	combination	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	12	_	NUM	_	NumType=Card	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	myristate	_	NOUN	_	Number=Sing	_	_	_	_
62	acetate	_	NOUN	_	Number=Sing	_	_	_	_
63	(	_	PUNCT	_	_	_	_	_	_
64	PMA	_	NOUN	_	Number=Sing	_	_	_	_
65	)	_	PUNCT	_	_	_	_	_	_
66	and	_	CCONJ	_	_	_	_	_	_
67	calcium	_	NOUN	_	Number=Sing	_	_	_	_
68	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
69	(	_	PUNCT	_	_	_	_	_	_
70	A23187	_	NOUN	_	Number=Sing	_	_	_	_
71	)	_	PUNCT	_	_	_	_	_	_
72	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
73	to	_	ADP	_	_	_	_	_	_
74	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
75	induction	_	NOUN	_	Number=Sing	_	_	_	_
76	of	_	ADP	_	_	_	_	_	_
77	genes	_	NOUN	_	Number=Plur	_	_	_	_
78	for	_	ADP	_	_	_	_	_	_
79	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
80	set	_	NOUN	_	Number=Sing	_	_	_	_
81	of	_	ADP	_	_	_	_	_	_
82	lymphokines	_	NOUN	_	Number=Plur	_	_	_	_
83	,	_	PUNCT	_	_	_	_	_	_
84	including	_	VERB	_	VerbForm=Ger	_	_	_	_
85	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
86	-	_	PUNCT	_	_	_	_	_	_
87	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
88	colony	_	NOUN	_	Number=Sing	_	_	_	_
89	-	_	PUNCT	_	_	_	_	_	_
90	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
91	factor	_	NOUN	_	Number=Sing	_	_	_	_
92	(	_	PUNCT	_	_	_	_	_	_
93	GM	_	PROPN	_	Number=Sing	_	_	_	_
94	-	_	PUNCT	_	_	_	_	_	_
95	CSF	_	PROPN	_	Number=Sing	_	_	_	_
96	)	_	PUNCT	_	_	_	_	_	_
97	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	earlier	_	ADJ	_	Degree=Cmp	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	SCONJ	_	PronType=Rel	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	mouse	_	NOUN	_	Number=Sing	_	_	_	_
13	GM	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	CSF	_	PROPN	_	Number=Sing	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	positions	_	NOUN	_	Number=Plur	_	_	_	_
19	between	_	ADP	_	_	_	_	_	_
20	-	_	SYM	_	_	_	_	_	_
21	95	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	73	_	NUM	_	NumType=Card	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	essential	_	ADJ	_	Degree=Pos	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	response	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	PMA	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	A23187	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	motifs	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	GM2	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	GC	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	box	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GM2	_	PROPN	_	Number=Sing	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	GGTAGTTCCC	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	GM2	_	PROPN	_	Number=Sing	_	_	_	_
16	;	_	PUNCT	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	CCGCCC	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
24	factors	_	NOUN	_	Number=Plur	_	_	_	_
25	A1	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	A2	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	elucidate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	GM	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	CSF	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	GM2	_	PROPN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	extract	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	basis	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	specific	_	ADJ	_	Degree=Pos	_	_	_	_
34	DNA	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	binding	_	NOUN	_	Number=Sing	_	_	_	_
37	activity	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	GM2	_	PROPN	_	Number=Sing	_	_	_	_
6	consists	_	VERB	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	50	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	p50	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	65	_	NUM	_	NumType=Card	_	_	_	_
14	kDa	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	p65	_	NUM	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	polypeptides	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	both	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	GM	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	CSF	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	immunoglobulin	_	PROPN	_	Number=Sing	_	_	_	_
33	kappa	_	PROPN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	GGAAAGTCCC	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretically	_	ADV	_	_	_	_	_	_
2	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	p50	_	NOUN	_	Number=Sing	_	_	_	_
4	alone	_	ADV	_	_	_	_	_	_
5	can	_	AUX	_	VerbForm=Fin	_	_	_	_
6	form	_	VERB	_	VerbForm=Inf	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	DNA	_	NOUN	_	Number=Sing	_	_	_	_
11	complex	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	mixture	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	p50	_	NUM	_	Number=Sing	_	_	_	_
19	associates	_	NOUN	_	Number=Plur	_	_	_	_
20	preferentially	_	ADV	_	_	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	p65	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	form	_	VERB	_	VerbForm=Inf	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	GM2	_	PROPN	_	Number=Sing	_	_	_	_
29	complex	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	p65	_	NOUN	_	Number=Sing	_	_	_	_
5	gave	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	per	_	ADP	_	_	_	_	_	_
7	se	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	low	_	ADJ	_	Degree=Pos	_	_	_	_
11	affinity	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	complex	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	migrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	more	_	ADV	_	_	_	_	_	_
21	slowly	_	ADV	_	_	_	_	_	_
22	than	_	ADP	_	_	_	_	_	_
23	native	_	ADJ	_	Degree=Pos	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	GM2	_	PROPN	_	Number=Sing	_	_	_	_
27	complex	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	antiserum	_	NOUN	_	Number=Sing	_	_	_	_
5	against	_	ADP	_	_	_	_	_	_
6	KBF1	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	identical	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	50	_	NUM	_	NumType=Card	_	_	_	_
11	kDa	_	PROPN	_	Number=Sing	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	reacted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	p50	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	GM2	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	GM2	_	PROPN	_	Number=Sing	_	_	_	_
33	polypeptide	_	NOUN	_	Number=Sing	_	_	_	_
34	can	_	AUX	_	VerbForm=Fin	_	_	_	_
35	not	_	PART	_	_	_	_	_	_
36	be	_	AUX	_	VerbForm=Inf	_	_	_	_
37	immunologically	_	ADV	_	_	_	_	_	_
38	differentiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	from	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	50	_	NUM	_	NumType=Card	_	_	_	_
42	kDa	_	NOUN	_	Number=Sing	_	_	_	_
43	subunit	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	NF	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	kappa	_	NOUN	_	Number=Sing	_	_	_	_
48	B.	_	PROPN	_	Number=Sing	_	_	_	_
49	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	NF	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	GM2	_	PROPN	_	Number=Sing	_	_	_	_
54	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	vitro	_	NOUN	_	Number=Sing	_	_	_	_
57	transcription	_	NOUN	_	Number=Sing	_	_	_	_
58	from	_	ADP	_	_	_	_	_	_
59	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
60	kappa	_	NOUN	_	Number=Sing	_	_	_	_
61	B	_	NOUN	_	Number=Sing	_	_	_	_
62	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
63	,	_	PUNCT	_	_	_	_	_	_
64	while	_	SCONJ	_	_	_	_	_	_
65	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
66	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
67	to	_	PART	_	_	_	_	_	_
68	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
69	transcription	_	NOUN	_	Number=Sing	_	_	_	_
70	from	_	ADP	_	_	_	_	_	_
71	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
72	GM	_	PROPN	_	Number=Sing	_	_	_	_
73	-	_	PUNCT	_	_	_	_	_	_
74	CSF	_	NOUN	_	Number=Sing	_	_	_	_
75	promoter	_	NOUN	_	Number=Sing	_	_	_	_
76	harboring	_	VERB	_	VerbForm=Ger	_	_	_	_
77	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
78	GM2	_	PROPN	_	Number=Sing	_	_	_	_
79	sequence	_	NOUN	_	Number=Sing	_	_	_	_
80	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	GM	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	CSF	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	through	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	GM2	_	PROPN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	GC	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	box	_	NOUN	_	Number=Sing	_	_	_	_
20	sequence	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	different	_	ADJ	_	Degree=Pos	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
32	alone	_	ADV	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001482	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Retinoic	_	ADJ	_	Number=Sing	_	_	_	_
2	acid	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	modulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Retinoic	_	PROPN	_	Degree=Pos	_	_	_	_
4	acid	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	RA	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	immune	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	effects	_	NOUN	_	Number=Plur	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	function	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	laboratory	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	RA	_	PROPN	_	Number=Sing	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vitro	_	ADJ	_	Number=Sing	_	_	_	_
11	polyclonal	_	ADJ	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	immunoglobulin	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	Ig	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Investigating	_	VERB	_	VerbForm=Ger	_	_	_	_
2	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
3	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
6	B	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	recently	_	ADV	_	_	_	_	_	_
13	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	6	_	NUM	_	NumType=Card	_	_	_	_
18	production	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	augmented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	RA	_	PROPN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	immune	_	NOUN	_	Number=Sing	_	_	_	_
10	modulating	_	VERB	_	Number=Sing	_	_	_	_
11	effects	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	RA	_	PROPN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	another	_	DET	_	_	_	_	_	_
21	important	_	ADJ	_	Degree=Pos	_	_	_	_
22	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	B	_	ADJ	_	Degree=Pos	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
27	production	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	receptors	_	NOUN	_	Number=Plur	_	_	_	_
36	on	_	ADP	_	_	_	_	_	_
37	T	_	PROPN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	RA	_	PROPN	_	Number=Sing	_	_	_	_
43	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
44	receptors	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	T	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	adenoidal	_	ADJ	_	Degree=Pos	_	_	_	_
10	tissues	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	incubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	RA	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	10	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	-	_	SYM	_	_	_	_	_	_
20	7	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	M	_	NOUN	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	DMSO	_	PROPN	_	Number=Sing	_	_	_	_
26	solvent	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	media	_	NOUN	_	Number=Sing	_	_	_	_
29	control	_	NOUN	_	Number=Sing	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	0	_	NUM	_	NumType=Card	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	6	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	SYM	_	_	_	_	_	_
35	8	_	NUM	_	NumType=Card	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	24	_	NUM	_	NumType=Card	_	_	_	_
39	h	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Total	_	ADJ	_	Degree=Pos	_	_	_	_
2	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	extracted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	T	_	ADJ	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	using	_	VERB	_	VerbForm=Ger	_	_	_	_
11	RT	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	PCR	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	changes	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	production	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	RA	_	PROPN	_	Number=Sing	_	_	_	_
25	receptors	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	RAR	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	beta	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	gamma	_	NOUN	_	Number=Sing	_	_	_	_
35	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
36	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	determined	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	RA	_	PROPN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	PROPN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	flow	_	NOUN	_	Number=Sing	_	_	_	_
17	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSION	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	RA	_	PROPN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	augment	_	VERB	_	VerbForm=Inf	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	possible	_	ADJ	_	Degree=Pos	_	_	_	_
19	paracrine	_	NOUN	_	Degree=Pos	_	_	_	_
20	effect	_	NOUN	_	Number=Sing	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2R	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	changes	_	NOUN	_	Number=Plur	_	_	_	_
3	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	RAR	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	PROPN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	another	_	DET	_	_	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
11	modulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	RA	_	PROPN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	immune	_	ADJ	_	Degree=Pos	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001483	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	inducible	_	ADJ	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	octamer	_	NOUN	_	Number=Sing	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-3	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	exclusively	_	ADV	_	_	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	natural	_	ADJ	_	Degree=Pos	_	_	_	_
15	killer	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	function	_	NOUN	_	Number=Sing	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	tightly	_	ADV	_	_	_	_	_	_
23	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	both	_	CCONJ	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	lineage	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	specific	_	ADJ	_	Degree=Pos	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
36	manner	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	functional	_	ADJ	_	Degree=Pos	_	_	_	_
10	importance	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	ACT	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1-activating	_	VERB	_	Number=Sing	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	3	_	NUM	_	NumType=Card	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	inducible	_	ADJ	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	over	_	ADP	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	5	_	NUM	_	NumType=Card	_	_	_	_
14	'	_	NOUN	_	_	_	_	_	_
15	end	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	3	_	NUM	_	NumType=Card	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	absence	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	other	_	ADJ	_	Degree=Pos	_	_	_	_
34	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
35	elements	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Over	_	ADP	_	_	_	_	_	_
2	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	'	_	NOUN	_	_	_	_	_	_
5	end	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
8	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	ubiquitously	_	ADV	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	constitutively	_	ADV	_	_	_	_	_	_
16	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	Oct	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	immunologically	_	ADV	_	_	_	_	_	_
10	related	_	ADJ	_	Degree=Pos	_	_	_	_
11	octamer	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
18	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	role	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	SCONJ	_	_	_	_	_	_
22	coordinating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	several	_	ADJ	_	Degree=Pos	_	_	_	_
27	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	elements	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
3	make	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	ACT	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	analogous	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	ARRE	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	despite	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	lack	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	sequence	_	NOUN	_	Number=Sing	_	_	_	_
9	homology	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	promoters	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	3	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	share	_	NOUN	_	Number=Sing	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	organizational	_	ADJ	_	Degree=Pos	_	_	_	_
24	pattern	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	elements	_	NOUN	_	Number=Plur	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	likely	_	ADJ	_	Degree=Pos	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	be	_	AUX	_	VerbForm=Inf	_	_	_	_
33	important	_	ADJ	_	Degree=Pos	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	specific	_	ADJ	_	Degree=Pos	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
42	genes	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001485	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	TCR	_	NOUN	_	Number=Sing	_	_	_	_
7	signals	_	NOUN	_	Number=Plur	_	_	_	_
8	synergize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	PROPN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1R	_	NUM	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	TCR	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	signals	_	NOUN	_	Number=Plur	_	_	_	_
21	can	_	AUX	_	VerbForm=Fin	_	_	_	_
22	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
23	synergistically	_	ADV	_	_	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	rate	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	several	_	ADJ	_	Degree=Pos	_	_	_	_
32	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
35	receptor	_	NOUN	_	Number=Sing	_	_	_	_
36	genes	_	NOUN	_	Number=Plur	_	_	_	_
37	during	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	competence	_	NOUN	_	Number=Sing	_	_	_	_
40	phase	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	activation	_	NOUN	_	Number=Sing	_	_	_	_
44	program	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	T	_	PROPN	_	Number=Sing	_	_	_	_
47	helper	_	NOUN	_	Number=Sing	_	_	_	_
48	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	how	_	ADV	_	PronType=Int	_	_	_	_
7	signals	_	NOUN	_	Number=Plur	_	_	_	_
8	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	type	_	NOUN	_	Number=Sing	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1R	_	NUM	_	Number=Sing	_	_	_	_
16	interact	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	signals	_	NOUN	_	Number=Plur	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	antigen	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	synergistically	_	ADV	_	_	_	_	_	_
25	augment	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	transactivating	_	NOUN	_	Number=Sing	_	_	_	_
28	properties	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	PROPN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
3	antigen	_	NOUN	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	signals	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	C	_	NOUN	_	Number=Sing	_	_	_	_
13	because	_	SCONJ	_	_	_	_	_	_
14	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
15	can	_	AUX	_	VerbForm=Fin	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	mimicked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
21	ester	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	13	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	acetate	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	not	_	ADV	_	_	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	calcium	_	NOUN	_	Number=Sing	_	_	_	_
33	ionophores	_	NOUN	_	Number=Plur	_	_	_	_
34	;	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
37	staurosporine	_	ADV	_	_	_	_	_	_
38	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
39	but	_	CCONJ	_	_	_	_	_	_
40	cyclosporine	_	NOUN	_	Number=Sing	_	_	_	_
41	resistant	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	shift	_	NOUN	_	Number=Sing	_	_	_	_
3	analyses	_	NOUN	_	Number=Plur	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	translocation	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	primarily	_	ADV	_	_	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	rather	_	ADV	_	_	_	_	_	_
20	than	_	ADP	_	_	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	signals	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	analyses	_	NOUN	_	Number=Plur	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
10	effect	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	functional	_	ADJ	_	Degree=Pos	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	independent	_	ADJ	_	Degree=Pos	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	kappa	_	VERB	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	alpha	_	PROPN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	MAD3	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	not	_	PART	_	_	_	_	_	_
40	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	with	_	ADP	_	_	_	_	_	_
42	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
43	kappa	_	VERB	_	Number=Sing	_	_	_	_
44	B	_	ADJ	_	Number=Sing	_	_	_	_
45	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
46	translocation	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	localization	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	transient	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	can	_	AUX	_	VerbForm=Fin	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	prolonged	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	either	_	CCONJ	_	_	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	signal	_	NOUN	_	Number=Sing	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	by	_	SCONJ	_	_	_	_	_	_
30	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	induces	_	VERB	_	Number=Plur	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	translocation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	s	_	X	_	_	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
26	for	_	SCONJ	_	_	_	_	_	_
27	terminating	_	VERB	_	VerbForm=Ger	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	DNA	_	NOUN	_	Number=Sing	_	_	_	_
34	interaction	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Antigen	_	NOUN	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	signals	_	NOUN	_	Number=Plur	_	_	_	_
4	prolong	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	DNA	_	PROPN	_	Number=Sing	_	_	_	_
11	interaction	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	probably	_	ADV	_	_	_	_	_	_
14	by	_	SCONJ	_	_	_	_	_	_
15	functionally	_	ADV	_	_	_	_	_	_
16	antagonizing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	s	_	X	_	_	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	transient	_	ADJ	_	Number=Sing	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappa	_	PROPN	_	Number=Sing	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	DNA	_	PROPN	_	Number=Sing	_	_	_	_
40	interaction	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	consequently	_	ADV	_	_	_	_	_	_
43	synergistically	_	ADV	_	_	_	_	_	_
44	enhance	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
45	IL	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	NF	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	kappa	_	NOUN	_	Number=Sing	_	_	_	_
53	B	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
56	gene	_	NOUN	_	Number=Sing	_	_	_	_
57	transcription	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001490	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	binding	_	VERB	_	Number=Sing	_	_	_	_
4	domain	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	A-MYB	_	PROPN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	B	_	NUM	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	binds	_	NOUN	_	Number=Plur	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	110	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kDa	_	NOUN	_	Number=Sing	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	studies	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	as	_	ADV	_	_	_	_	_	_
4	well	_	ADV	_	Degree=Pos	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	use	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
10	animals	_	NOUN	_	Number=Plur	_	_	_	_
11	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	A-MYB	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	central	_	ADJ	_	Degree=Pos	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	specific	_	ADJ	_	Degree=Pos	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	regulation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	mature	_	ADJ	_	Degree=Pos	_	_	_	_
28	B	_	NOUN	_	Degree=Pos	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	highly	_	ADV	_	_	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	Burkitt	_	PROPN	_	Number=Sing	_	_	_	_
9	's	_	PART	_	_	_	_	_	_
10	lymphoma	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	disease	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	therefore	_	ADV	_	_	_	_	_	_
4	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	A-MYB	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	several	_	ADJ	_	Degree=Pos	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lines	_	NOUN	_	Number=Plur	_	_	_	_
19	using	_	VERB	_	VerbForm=Ger	_	_	_	_
20	co-transfection	_	NOUN	_	Number=Sing	_	_	_	_
21	assays	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	A-MYB	_	PROPN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	transcriptionally	_	ADV	_	_	_	_	_	_
28	active	_	ADJ	_	Degree=Pos	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	all	_	DET	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	lines	_	NOUN	_	Number=Plur	_	_	_	_
35	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	but	_	CCONJ	_	_	_	_	_	_
38	not	_	PART	_	_	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	T	_	NOUN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	particular	_	ADJ	_	Degree=Pos	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	best	_	ADJ	_	Degree=Sup	_	_	_	_
5	responder	_	NOUN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	line	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	Burkitt	_	PROPN	_	Number=Sing	_	_	_	_
11	's	_	PART	_	_	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	line	_	NOUN	_	Number=Sing	_	_	_	_
14	Namalwa	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	A	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	MYB	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	when	_	ADV	_	PronType=Int	_	_	_	_
16	either	_	CCONJ	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	artificial	_	ADJ	_	Degree=Pos	_	_	_	_
19	construct	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	c-MYC	_	NOUN	_	Number=Sing	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	as	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	reporter	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	functional	_	ADJ	_	Degree=Pos	_	_	_	_
5	domains	_	NOUN	_	Number=Plur	_	_	_	_
6	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	DNA	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	negative	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	previously	_	ADV	_	_	_	_	_	_
18	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	fibroblast	_	ADJ	_	Degree=Pos	_	_	_	_
22	context	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	have	_	VERB	_	VerbForm=Inf	_	_	_	_
28	similar	_	ADJ	_	Degree=Pos	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	B	_	ADJ	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	A-MYB	_	PROPN	_	Number=Sing	_	_	_	_
5	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	N-terminal	_	ADJ	_	Number=Sing	_	_	_	_
18	218	_	NUM	_	NumType=Card	_	_	_	_
19	amino	_	NOUN	_	Degree=Pos	_	_	_	_
20	acids	_	NOUN	_	Number=Plur	_	_	_	_
21	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	DNA	_	PROPN	_	Number=Sing	_	_	_	_
24	binding	_	VERB	_	Number=Sing	_	_	_	_
25	domain	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	110	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kDa	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	all	_	DET	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	not	_	ADV	_	_	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	lines	_	NOUN	_	Number=Plur	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	specifically	_	ADV	_	_	_	_	_	_
27	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	A-MYB	_	ADJ	_	Degree=Pos	_	_	_	_
31	N	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	terminal	_	NOUN	_	Number=Sing	_	_	_	_
34	domain	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	hypothesize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	110	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kDa	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	may	_	AUX	_	VerbForm=Fin	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	functionally	_	ADV	_	_	_	_	_	_
13	important	_	ADJ	_	Degree=Pos	_	_	_	_
14	B	_	NOUN	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	co-activator	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	A	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	MYB	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001494	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	normal	_	ADJ	_	Degree=Pos	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	cycle	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	program	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	exploited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	infection	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	quiescent	_	ADJ	_	Degree=Pos	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	Barr	_	PROPN	_	Number=Sing	_	_	_	_
20	virus	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	B	_	ADJ	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
6	circulation	_	NOUN	_	Number=Sing	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	maintained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	non-proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
12	state	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Antigen	_	ADJ	_	Degree=Pos	_	_	_	_
2	recognition	_	NOUN	_	Number=Sing	_	_	_	_
3	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	limited	_	ADJ	_	Degree=Pos	_	_	_	_
5	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	whereas	_	SCONJ	_	_	_	_	_	_
8	infection	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Barr	_	PROPN	_	Number=Sing	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	EBV	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	results	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	continual	_	ADJ	_	Degree=Pos	_	_	_	_
20	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	outgrowth	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	immortal	_	ADJ	_	Degree=Pos	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	lines	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	clear	_	ADJ	_	Degree=Pos	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	which	_	DET	_	PronType=Int	_	_	_	_
8	point	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	cycle	_	NOUN	_	Number=Sing	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	arrested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	characterized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	several	_	ADJ	_	Degree=Pos	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	cycle	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	associated	_	VERB	_	Degree=Pos	_	_	_	_
29	genes	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	quiescent	_	ADJ	_	Degree=Pos	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	four	_	NUM	_	NumType=Card	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	cdc	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
16	E	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	CD23	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
22	D2	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	up	_	ADV	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	approximately	_	ADV	_	_	_	_	_	_
29	100	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	fold	_	NOUN	_	Number=Sing	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	result	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	EBV	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
39	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	genes	_	NOUN	_	Number=Plur	_	_	_	_
4	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	positive	_	ADJ	_	Degree=Pos	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	switch	_	NOUN	_	Number=Sing	_	_	_	_
18	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	SCONJ	_	_	_	_	_	_
20	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
21	entry	_	NOUN	_	Number=Sing	_	_	_	_
22	into	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	cycle	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	quiescent	_	ADJ	_	Degree=Pos	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	either	_	CCONJ	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	cocktail	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	anti-CD40	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	anti-IgM	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	IL4	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	EBV	_	NOUN	_	Number=Sing	_	_	_	_
21	results	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	same	_	ADJ	_	Degree=Pos	_	_	_	_
29	four	_	NUM	_	NumType=Card	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
33	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	after	_	ADP	_	_	_	_	_	_
36	infection	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	EBV	_	PROPN	_	Number=Sing	_	_	_	_
39	exploits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	normal	_	ADJ	_	Degree=Pos	_	_	_	_
42	program	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	B	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	lymphocyte	_	NOUN	_	Degree=Pos	_	_	_	_
47	cell	_	NOUN	_	Number=Sing	_	_	_	_
48	cycle	_	NOUN	_	Number=Sing	_	_	_	_
49	activation	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001496	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Anti	_	X	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Ehrlichia	_	PROPN	_	Number=Sing	_	_	_	_
4	chaffeensis	_	NOUN	_	Number=Sing	_	_	_	_
5	antibody	_	NOUN	_	Number=Sing	_	_	_	_
6	complexed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	E.	_	PROPN	_	Number=Sing	_	_	_	_
9	chaffeensis	_	PROPN	_	Number=Sing	_	_	_	_
10	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	potent	_	ADJ	_	Degree=Pos	_	_	_	_
12	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
14	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	through	_	ADP	_	_	_	_	_	_
20	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	reduction	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	IkappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Ehrlichia	_	PROPN	_	Number=Sing	_	_	_	_
2	chaffeensis	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	obligatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	bacterium	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	infects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	etiologic	_	ADJ	_	Degree=Pos	_	_	_	_
17	agent	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	ehrlichiosis	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	United	_	PROPN	_	Number=Sing	_	_	_	_
24	States	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	previous	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	exposure	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	E.	_	PROPN	_	Number=Sing	_	_	_	_
13	chaffeensis	_	PROPN	_	Number=Sing	_	_	_	_
14	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1beta	_	PROPN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1beta	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	8	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	10	_	NUM	_	NumType=Card	_	_	_	_
35	genes	_	NOUN	_	Number=Plur	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	vitro	_	NOUN	_	Number=Sing	_	_	_	_
38	but	_	CCONJ	_	_	_	_	_	_
39	not	_	ADV	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	tumor	_	NOUN	_	Number=Sing	_	_	_	_
44	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
45	factor	_	NOUN	_	Number=Sing	_	_	_	_
46	alpha	_	PROPN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	TNF	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	alpha	_	PROPN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	IL	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	6	_	NUM	_	NumType=Card	_	_	_	_
56	mRNAs	_	PROPN	_	Number=Plur	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	anti-E	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	chaffeensis	_	PROPN	_	Number=Sing	_	_	_	_
2	antibody	_	NOUN	_	Number=Sing	_	_	_	_
3	complexed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	E.	_	PROPN	_	Number=Sing	_	_	_	_
6	chaffeensis	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	major	_	ADJ	_	Degree=Pos	_	_	_	_
12	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	line	_	NOUN	_	Number=Sing	_	_	_	_
5	THP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	E.	_	PROPN	_	Number=Sing	_	_	_	_
12	chaffeensis	_	NOUN	_	Number=Sing	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	preincubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	anti-E	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	chaffeensis	_	PROPN	_	Number=Sing	_	_	_	_
2	serum	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	h	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
12	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	competitive	_	ADJ	_	Degree=Pos	_	_	_	_
17	reverse	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	PCR	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Anti-E.	_	ADJ	_	_	_	_	_	_
2	chaffeensis	_	PROPN	_	Number=Sing	_	_	_	_
3	antibody	_	NOUN	_	Number=Sing	_	_	_	_
4	complexed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	E.	_	PROPN	_	Number=Sing	_	_	_	_
7	chaffeensis	_	PROPN	_	Number=Sing	_	_	_	_
8	significantly	_	ADV	_	_	_	_	_	_
9	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1beta	_	PROPN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	THP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1beta	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	TNF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	6	_	NUM	_	NumType=Card	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	24	_	NUM	_	NumType=Card	_	_	_	_
19	h	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	Escherichia	_	PROPN	_	Number=Sing	_	_	_	_
29	coli	_	NOUN	_	Number=Sing	_	_	_	_
30	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
31	at	_	ADP	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	microg	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	ml	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Fab	_	ADJ	_	Degree=Pos	_	_	_	_
2	fragment	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	anti-E	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	chaffeensis	_	PROPN	_	Number=Sing	_	_	_	_
2	immunoglobulin	_	PROPN	_	Number=Sing	_	_	_	_

1	G	_	PROPN	_	Number=Sing	_	_	_	_
2	complexed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	E.	_	PROPN	_	Number=Sing	_	_	_	_
5	chaffeensis	_	PROPN	_	Number=Sing	_	_	_	_
6	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
9	any	_	DET	_	_	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	three	_	NUM	_	NumType=Card	_	_	_	_
13	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	ehrlichial	_	ADJ	_	Degree=Pos	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1beta	_	PROPN	_	Number=Sing	_	_	_	_
25	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	that	_	DET	_	_	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	immune	_	ADJ	_	Number=Sing	_	_	_	_
33	complex	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	Fc	_	PROPN	_	Number=Sing	_	_	_	_
37	gamma	_	NOUN	_	Number=Sing	_	_	_	_
38	receptor	_	NOUN	_	Number=Sing	_	_	_	_
39	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	TNF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	alpha	_	PROPN	_	Number=Sing	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	IL	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	6	_	NUM	_	NumType=Card	_	_	_	_
49	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
50	expression	_	NOUN	_	Number=Sing	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
53	IL	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	1beta	_	PROPN	_	Number=Sing	_	_	_	_
56	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
57	expression	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	prolonged	_	VERB	_	Degree=Pos	_	_	_	_
4	degradation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	THP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	anti-E	_	ADJ	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	chaffeensis	_	PROPN	_	Number=Sing	_	_	_	_
2	serum	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	E.	_	PROPN	_	Number=Sing	_	_	_	_
5	chaffeensis	_	PROPN	_	Number=Sing	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	result	_	NOUN	_	Number=Sing	_	_	_	_
3	implies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	DET	_	_	_	_	_	_
5	development	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	anti-E	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	chaffeensis	_	PROPN	_	Number=Sing	_	_	_	_
2	antibody	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	patients	_	NOUN	_	Number=Sing	_	_	_	_
5	can	_	AUX	_	VerbForm=Fin	_	_	_	_
6	result	_	VERB	_	VerbForm=Inf	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	major	_	ADJ	_	Degree=Pos	_	_	_	_
12	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	play	_	VERB	_	VerbForm=Inf	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	important	_	ADJ	_	Degree=Pos	_	_	_	_
20	role	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	pathophysiology	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	ehrlichiosis	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	immune	_	ADJ	_	Degree=Pos	_	_	_	_
28	responses	_	NOUN	_	Number=Plur	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001497	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	AT	_	ADP	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	:	_	PUNCT	_	_	_	_	_	_
15	implications	_	NOUN	_	Number=Plur	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	differential	_	ADJ	_	Degree=Pos	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	helper	_	NOUN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	subsets	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	individual	_	ADJ	_	Degree=Pos	_	_	_	_
4	CD4	_	NOUN	_	Number=Sing	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_

1	T	_	X	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	results	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	differential	_	ADJ	_	Degree=Pos	_	_	_	_
6	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	preferentially	_	ADV	_	_	_	_	_	_
18	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	helper	_	NOUN	_	Number=Sing	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	TH1	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	involved	_	ADJ	_	Degree=Pos	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
36	immune	_	NOUN	_	Number=Sing	_	_	_	_
37	responses	_	NOUN	_	Number=Plur	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	whereas	_	SCONJ	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	4	_	NUM	_	NumType=Card	_	_	_	_
43	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
44	synthesized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	by	_	ADP	_	_	_	_	_	_
46	TH2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	which	_	PRON	_	PronType=Rel	_	_	_	_
50	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
51	essential	_	ADJ	_	Degree=Pos	_	_	_	_
52	for	_	ADP	_	_	_	_	_	_
53	humoral	_	ADJ	_	Degree=Pos	_	_	_	_
54	immunity	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Ca	_	PROPN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	+)-	_	SYM	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	ATp	_	PROPN	_	Number=Sing	_	_	_	_
11	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	key	_	ADJ	_	Degree=Pos	_	_	_	_
14	role	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
22	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	while	_	SCONJ	_	_	_	_	_	_
4	IL2	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	contribution	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Ca	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	+)-	_	SYM	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	protein	_	VERB	_	Number=Sing	_	_	_	_
16	kinase	_	NOUN	_	Number=Sing	_	_	_	_
17	C	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	signals	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
23	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	that	_	DET	_	_	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	IL4	_	NOUN	_	Number=Sing	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	through	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	Ca	_	PROPN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	+)-	_	SYM	_	_	_	_	_	_
36	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
37	pathway	_	NOUN	_	Number=Sing	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	diminished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	protein	_	NOUN	_	Number=Sing	_	_	_	_
42	kinase	_	NOUN	_	Number=Sing	_	_	_	_
43	C	_	NOUN	_	Number=Sing	_	_	_	_
44	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
47	T	_	NOUN	_	Number=Sing	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	due	_	ADP	_	_	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	mutually	_	ADV	_	_	_	_	_	_
7	exclusive	_	ADJ	_	Degree=Pos	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	ATp	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	P	_	NOUN	_	Number=Sing	_	_	_	_
21	sequence	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	element	_	NOUN	_	Number=Sing	_	_	_	_
25	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	69	_	NUM	_	NumType=Card	_	_	_	_
27	bp	_	NOUN	_	Number=Sing	_	_	_	_
28	upstream	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	IL4	_	PROPN	_	Number=Sing	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	initiation	_	NOUN	_	Number=Sing	_	_	_	_
34	site	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	IL4	_	PROPN	_	Number=Sing	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	downregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
22	tumor	_	NOUN	_	Number=Sing	_	_	_	_
23	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	RelA	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	overexpressing	_	ADJ	_	Degree=Pos	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	C	_	PROPN	_	Number=Sing	_	_	_	_
7	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	RelA	_	PROPN	_	Degree=Pos	_	_	_	_
10	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
11	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	IL4	_	NOUN	_	Number=Sing	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	mouse	_	NOUN	_	Number=Sing	_	_	_	_
24	P	_	NOUN	_	Number=Sing	_	_	_	_
25	sequence	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	affinity	_	NOUN	_	Number=Sing	_	_	_	_
33	site	_	NOUN	_	Number=Sing	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	ATp	_	PROPN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	affinity	_	NOUN	_	Number=Sing	_	_	_	_
43	site	_	NOUN	_	Number=Sing	_	_	_	_
44	for	_	ADP	_	_	_	_	_	_
45	RelA	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	competition	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	general	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	activators	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	RelA	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	ATp	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
19	effect	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	kinase	_	NOUN	_	Number=Sing	_	_	_	_
23	C	_	PROPN	_	Number=Sing	_	_	_	_
24	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	IL4	_	PROPN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	may	_	AUX	_	VerbForm=Fin	_	_	_	_
30	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	differential	_	ADJ	_	Degree=Pos	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	TH	_	ADJ	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001505	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Barr	_	PROPN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	latent	_	ADJ	_	Number=Sing	_	_	_	_
9	infection	_	NOUN	_	Number=Sing	_	_	_	_
10	membrane	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	activates	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	through	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	pathway	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
34	kinases	_	NOUN	_	Number=Plur	_	_	_	_
35	IKKalpha	_	PROPN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	IKKbeta	_	PROPN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Barr	_	PROPN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	oncoprotein	_	NOUN	_	_	_	_	_	_
7	latent	_	ADJ	_	Degree=Pos	_	_	_	_
8	infection	_	NOUN	_	Number=Sing	_	_	_	_
9	membrane	_	NOUN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	constitutively	_	ADV	_	_	_	_	_	_
18	aggregated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	pseudo	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	tumor	_	NOUN	_	Number=Sing	_	_	_	_
22	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	TNFR	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
35	through	_	ADP	_	_	_	_	_	_
36	two	_	NUM	_	NumType=Card	_	_	_	_
37	sites	_	NOUN	_	Number=Plur	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
40	C	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
43	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
44	domain	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	site	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	similar	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	TNFRII	_	PROPN	_	Number=Sing	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	associating	_	VERB	_	VerbForm=Ger	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	TNFR	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	TRAF1	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	similar	_	ADJ	_	Degree=Pos	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	TNFRI	_	PROPN	_	Number=Sing	_	_	_	_
27	in	_	SCONJ	_	_	_	_	_	_
28	associating	_	VERB	_	VerbForm=Ger	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	TNFRI	_	PROPN	_	Number=Sing	_	_	_	_
32	death	_	NOUN	_	Number=Sing	_	_	_	_
33	domain	_	NOUN	_	Number=Sing	_	_	_	_
34	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	TRADD	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	TNFRI	_	PROPN	_	Number=Sing	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	recently	_	ADV	_	_	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	association	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	TRADD	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	RIP	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
20	;	_	PUNCT	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
29	kinase	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	NIK	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	;	_	PUNCT	_	_	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
38	alpha	_	NOUN	_	Number=Sing	_	_	_	_
39	kinases	_	NOUN	_	Number=Plur	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	IKKalpha	_	PROPN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	IKKbeta	_	PROPN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	;	_	PUNCT	_	_	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
50	alpha	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
2	alpha	_	NOUN	_	Number=Sing	_	_	_	_
3	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	Ser	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	32	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	Ser	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	36	_	NUM	_	NumType=Card	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	followed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	degradation	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	each	_	DET	_	_	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	effector	_	NOUN	_	Number=Sing	_	_	_	_
20	sites	_	NOUN	_	Number=Plur	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	pathway	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	NIK	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	IKKalpha	_	PROPN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	IKKbeta	_	PROPN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Dominant	_	ADJ	_	Degree=Pos	_	_	_	_
2	negative	_	ADJ	_	Degree=Pos	_	_	_	_
3	mutants	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NIK	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	IKKalpha	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	IKKbeta	_	PROPN	_	Number=Sing	_	_	_	_
11	substantially	_	ADV	_	_	_	_	_	_
12	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	each	_	DET	_	_	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	effector	_	NOUN	_	Number=Sing	_	_	_	_
25	sites	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001507	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	vitro	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	vivo	_	NOUN	_	Number=Sing	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	role	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	26	_	NUM	_	NumType=Card	_	_	_	_
17	S	_	PROPN	_	Number=Sing	_	_	_	_
18	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	becoming	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
4	increasingly	_	ADV	_	_	_	_	_	_
5	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	critical	_	ADJ	_	Degree=Pos	_	_	_	_
14	role	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	SCONJ	_	_	_	_	_	_
16	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Data	_	NOUN	_	Number=Sing	_	_	_	_
2	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
7	laboratories	_	NOUN	_	Number=Plur	_	_	_	_
8	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
12	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	important	_	ADJ	_	Degree=Pos	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	cascade	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	SCONJ	_	_	_	_	_	_
21	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	PROPN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Indeed	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	availability	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	selective	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	orally	_	ADV	_	_	_	_	_	_
9	active	_	ADJ	_	Degree=Pos	_	_	_	_
10	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
11	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
12	should	_	AUX	_	VerbForm=Fin	_	_	_	_
13	prove	_	VERB	_	VerbForm=Inf	_	_	_	_
14	useful	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	SCONJ	_	_	_	_	_	_
16	delineating	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	roles	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	other	_	ADJ	_	Degree=Pos	_	_	_	_
29	pathophysiological	_	ADJ	_	Degree=Pos	_	_	_	_
30	conditions	_	NOUN	_	Number=Plur	_	_	_	_
31	such	_	ADJ	_	Degree=Pos	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	cancer	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	heart	_	NOUN	_	Number=Sing	_	_	_	_
36	disease	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001511	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transactivation	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	II	_	NUM	_	NumType=Card	_	_	_	_
8	bare	_	VERB	_	Degree=Pos	_	_	_	_
9	lymphocyte	_	ADJ	_	Degree=Pos	_	_	_	_
10	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	participation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
19	regions	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	TATA	_	NOUN	_	Number=Sing	_	_	_	_
23	box	_	NOUN	_	Number=Sing	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	positive	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulator	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	class	_	NOUN	_	Number=Sing	_	_	_	_
8	II	_	NUM	_	NumType=Card	_	_	_	_
9	major	_	ADJ	_	Degree=Pos	_	_	_	_
10	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
11	complex	_	ADJ	_	Degree=Pos	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	defective	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	one	_	NUM	_	NumType=Card	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	five	_	NUM	_	NumType=Card	_	_	_	_
26	complementation	_	NOUN	_	Number=Sing	_	_	_	_
27	groups	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	class	_	NOUN	_	Number=Sing	_	_	_	_
30	II	_	NUM	_	NumType=Card	_	_	_	_
31	major	_	ADJ	_	Degree=Pos	_	_	_	_
32	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
33	complex	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	negative	_	ADJ	_	Degree=Pos	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	lines	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	N-	_	ADJ	_	_	_	_	_	_
3	terminal	_	NOUN	_	Number=Sing	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	capable	_	ADJ	_	Degree=Pos	_	_	_	_
7	of	_	SCONJ	_	_	_	_	_	_
8	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	reporter	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	when	_	ADV	_	PronType=Int	_	_	_	_
15	fused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	DNA	_	PROPN	_	Number=Sing	_	_	_	_
19	binding	_	VERB	_	Number=Sing	_	_	_	_
20	domain	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
8	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	domain	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	SCONJ	_	_	_	_	_	_
15	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
16	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	process	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	initiation	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	elongation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Specifically	_	ADV	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	specificity	_	NOUN	_	Number=Sing	_	_	_	_
5	TBP	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	TATA	_	PROPN	_	Number=Sing	_	_	_	_
8	box	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	assay	_	PROPN	_	Number=Sing	_	_	_	_
13	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
15	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	domain	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	mutations	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	TBP	_	PROPN	_	Number=Sing	_	_	_	_
29	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	disrupt	_	VERB	_	VerbForm=Inf	_	_	_	_
32	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
33	interaction	_	NOUN	_	Number=Sing	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
36	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	general	_	ADJ	_	Degree=Pos	_	_	_	_
38	factors	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Transactivation	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	extremely	_	ADV	_	_	_	_	_	_
6	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	mutation	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	TBP	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	yeast	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	abolish	_	VERB	_	VerbForm=Inf	_	_	_	_
19	VP16	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	leaves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	basal	_	ADJ	_	Degree=Pos	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	TBP	_	NOUN	_	Number=Sing	_	_	_	_
3	mutant	_	NOUN	_	Number=Sing	_	_	_	_
4	defective	_	ADJ	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	interaction	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	TBP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	TAFII250	_	PROPN	_	Number=Sing	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	domain	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Certain	_	ADJ	_	Degree=Pos	_	_	_	_
2	interactions	_	NOUN	_	Number=Plur	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	TBP	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	general	_	ADJ	_	Degree=Pos	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	specifically	_	ADV	_	_	_	_	_	_
11	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	acidic	_	ADJ	_	Degree=Pos	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	domains	_	NOUN	_	Number=Plur	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	also	_	ADV	_	_	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
23	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	reach	_	VERB	_	VerbForm=Inf	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	full	_	ADJ	_	Degree=Pos	_	_	_	_
28	potential	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	like	_	ADP	_	_	_	_	_	_
4	VP16	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	able	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	elongation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Overall	_	ADV	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	B-cell	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	very	_	ADV	_	_	_	_	_	_
15	similar	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
18	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	herpes	_	NOUN	_	Number=Sing	_	_	_	_
22	virus	_	NOUN	_	Number=Sing	_	_	_	_
23	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
24	VP16	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	ways	_	NOUN	_	Number=Plur	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
31	tested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001513	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transactivation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
11	6	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	HHV	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	strains	_	VERB	_	Number=Plur	_	_	_	_
18	GS	_	PROPN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	Z	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	29	_	NUM	_	NumType=Card	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	primary	_	ADJ	_	Degree=Pos	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	identification	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	transactivating	_	VERB	_	VerbForm=Ger	_	_	_	_
32	HHV	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	6	_	NUM	_	NumType=Card	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	GS	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	fragments	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
3	6	_	NUM	_	NumType=Card	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	HHV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	6	_	NUM	_	NumType=Card	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	accelerate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	cytopathic	_	ADJ	_	Degree=Pos	_	_	_	_
22	effects	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	HIV	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	examines	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	regions	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	HHV	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	6	_	NUM	_	NumType=Card	_	_	_	_
15	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	heterogeneous	_	ADJ	_	Degree=Pos	_	_	_	_
19	population	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	primary	_	ADJ	_	Degree=Pos	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	without	_	ADP	_	_	_	_	_	_
28	antigenic	_	ADJ	_	Degree=Pos	_	_	_	_
29	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	different	_	ADJ	_	Degree=Pos	_	_	_	_
3	strains	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	HHV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	6	_	NUM	_	NumType=Card	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	GS	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	Z29	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	transactivated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GS	_	PROPN	_	Number=Sing	_	_	_	_
3	strain	_	NOUN	_	Number=Sing	_	_	_	_
4	transactivated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	both	_	DET	_	_	_	_	_	_
9	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	while	_	SCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	Z29	_	PROPN	_	Number=Sing	_	_	_	_
18	strain	_	NOUN	_	Number=Sing	_	_	_	_
19	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	only	_	ADV	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Three	_	NUM	_	NumType=Card	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	clones	_	NOUN	_	Number=Plur	_	_	_	_
4	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	HHV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	6	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	GS	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
12	fragments	_	NOUN	_	Number=Plur	_	_	_	_
13	transactivated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	cotransfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	21.4	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kb	_	NOUN	_	Number=Sing	_	_	_	_
5	DNA	_	NOUN	_	Number=Sing	_	_	_	_
6	clone	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	pZVB70	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	highest	_	ADJ	_	Degree=Sup	_	_	_	_
13	transactivating	_	NOUN	_	Number=Sing	_	_	_	_
14	ability	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	while	_	SCONJ	_	_	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	DNA	_	PROPN	_	Number=Sing	_	_	_	_
20	fragments	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	pZVB10	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	6.2	_	NUM	_	NumType=Card	_	_	_	_
25	kb	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	pZVH14	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	8.7	_	NUM	_	NumType=Card	_	_	_	_
31	kb	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
36	activity	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	clones	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	pZVH14	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	construct	_	NOUN	_	Number=Sing	_	_	_	_
13	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	mutation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	mutated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	kappa	_	PROPN	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	transactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	during	_	ADP	_	_	_	_	_	_
13	HHV	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	GS	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	infection	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	after	_	ADP	_	_	_	_	_	_
22	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	pZVB70	_	NOUN	_	Number=Sing	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	pZVB10	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	sites	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	essential	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
19	during	_	ADP	_	_	_	_	_	_
20	HHV	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	6	_	NUM	_	NumType=Card	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	GS	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	infection	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	HIV	_	NOUN	_	Number=Sing	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	primary	_	ADJ	_	Degree=Pos	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	HHV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	consequently	_	ADV	_	_	_	_	_	_
16	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	replication	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	increase	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	cytopathic	_	ADJ	_	Degree=Pos	_	_	_	_
27	effect	_	NOUN	_	Number=Sing	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	coinfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001514	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	HIV1	_	NOUN	_	Degree=Pos	_	_	_	_
2	infection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
8	promotes	_	VERB	_	Number=Plur	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	translocation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	KB	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	related	_	ADJ	_	Degree=Pos	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	1991	_	NUM	_	NumType=Card	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	using	_	VERB	_	VerbForm=Ger	_	_	_	_
8	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
9	mobility	_	NOUN	_	Number=Sing	_	_	_	_
10	shift	_	NOUN	_	Number=Sing	_	_	_	_
11	assays	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	3	_	NUM	_	NumType=Card	_	_	_	_
15	different	_	ADJ	_	Degree=Pos	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	B1	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	B2	_	PROPN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	B3	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	affinity	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	KB	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
32	target	_	NOUN	_	Number=Sing	_	_	_	_
33	sequence	_	NOUN	_	Number=Sing	_	_	_	_
34	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	specifically	_	ADV	_	_	_	_	_	_
36	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
39	extracts	_	NOUN	_	Number=Plur	_	_	_	_
40	from	_	ADP	_	_	_	_	_	_
41	HIV1	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	B2	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	only	_	ADV	_	_	_	_	_	_
13	upon	_	ADP	_	_	_	_	_	_
14	HIV1	_	NOUN	_	Number=Sing	_	_	_	_
15	infection	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	B3	_	PROPN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	only	_	ADV	_	_	_	_	_	_
6	slightly	_	ADV	_	_	_	_	_	_
7	evident	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	uninfected	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	readily	_	ADV	_	_	_	_	_	_
16	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	very	_	ADV	_	_	_	_	_	_
5	low	_	ADV	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HIV1	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	paper	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	B2	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	DNA	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	binding	_	VERB	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	not	_	PART	_	_	_	_	_	_
32	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	IKB	_	PROPN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	clustered	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	translocated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
14	only	_	ADV	_	_	_	_	_	_
15	after	_	ADP	_	_	_	_	_	_
16	HIV1	_	NOUN	_	Number=Sing	_	_	_	_
17	infection	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	B3	_	PROPN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
9	only	_	ADV	_	_	_	_	_	_
10	when	_	ADV	_	PronType=Int	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	HIV1	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HIV1	_	NOUN	_	Number=Sing	_	_	_	_
5	infection	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	translocation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001522	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	parasite	_	NOUN	_	Number=Sing	_	_	_	_
4	Theileria	_	PROPN	_	Number=Sing	_	_	_	_
5	parva	_	NOUN	_	Number=Sing	_	_	_	_
6	protects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Parasites	_	NOUN	_	Number=Plur	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	evolved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	plethora	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	strategies	_	NOUN	_	Number=Plur	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	ensure	_	VERB	_	VerbForm=Inf	_	_	_	_
10	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	survival	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	parasite	_	NOUN	_	Number=Sing	_	_	_	_
4	Theileria	_	PROPN	_	Number=Sing	_	_	_	_
5	parva	_	NOUN	_	Number=Sing	_	_	_	_
6	secures	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
8	propagation	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	spreads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	animal	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	SCONJ	_	_	_	_	_	_
16	infecting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	continuous	_	ADJ	_	Degree=Pos	_	_	_	_
25	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	rendering	_	VERB	_	VerbForm=Ger	_	_	_	_
28	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
29	metastatic	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	previous	_	ADJ	_	Degree=Pos	_	_	_	_
3	work	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	parasite	_	NOUN	_	Number=Sing	_	_	_	_
11	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	by	_	SCONJ	_	_	_	_	_	_
23	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
26	degradation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
29	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
30	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	biological	_	ADJ	_	Degree=Pos	_	_	_	_
3	significance	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	T.	_	PROPN	_	Number=Sing	_	_	_	_
11	parva	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	however	_	ADV	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	yet	_	ADV	_	_	_	_	_	_
21	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
22	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Cells	_	NOUN	_	Number=Plur	_	_	_	_
2	that	_	PRON	_	PronType=Rel	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	transformed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	viruses	_	NOUN	_	Number=Plur	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	persist	_	VERB	_	VerbForm=Inf	_	_	_	_
12	only	_	ADV	_	_	_	_	_	_
13	if	_	SCONJ	_	_	_	_	_	_
14	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
15	manage	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	avoid	_	VERB	_	VerbForm=Inf	_	_	_	_
18	destruction	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
22	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	transformation	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
30	contribute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	maintain	_	VERB	_	VerbForm=Inf	_	_	_	_
33	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
34	homeostasis	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	parasite	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	survival	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	T.	_	PROPN	_	Number=Sing	_	_	_	_
21	parva	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	by	_	SCONJ	_	_	_	_	_	_
4	conveying	_	VERB	_	VerbForm=Ger	_	_	_	_
5	protection	_	NOUN	_	Number=Sing	_	_	_	_
6	against	_	ADP	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
9	signal	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	accompanies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	parasite	_	ADJ	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
15	transformation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Consequently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	translocation	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
15	negative	_	ADJ	_	Degree=Pos	_	_	_	_
16	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
17	forms	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	components	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	pathway	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	such	_	ADJ	_	Degree=Pos	_	_	_	_
29	as	_	ADP	_	_	_	_	_	_
30	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	p65	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	prompt	_	ADJ	_	Degree=Pos	_	_	_	_
35	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
36	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	T.	_	PROPN	_	Number=Sing	_	_	_	_
39	parva	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	T	_	NOUN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	offer	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	important	_	ADJ	_	Degree=Pos	_	_	_	_
5	insights	_	NOUN	_	Number=Plur	_	_	_	_
6	into	_	ADP	_	_	_	_	_	_
7	parasite	_	ADJ	_	Degree=Pos	_	_	_	_
8	survival	_	NOUN	_	Number=Sing	_	_	_	_
9	strategies	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	parasite	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
17	NF	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	essential	_	ADJ	_	Degree=Pos	_	_	_	_
24	step	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	SCONJ	_	_	_	_	_	_
26	maintaining	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001525	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	TAL1	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	LIM	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	only	_	ADV	_	_	_	_	_	_
6	proteins	_	VERB	_	Number=Plur	_	_	_	_
7	synergistically	_	ADV	_	_	_	_	_	_
8	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	retinaldehyde	_	NOUN	_	Number=Sing	_	_	_	_
10	dehydrogenase	_	NOUN	_	Number=Sing	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
15	acute	_	ADJ	_	Degree=Pos	_	_	_	_
16	lymphoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
17	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	SCONJ	_	_	_	_	_	_
19	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	cofactors	_	NOUN	_	Number=Plur	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	GATA3	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Previously	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	LIM	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	only	_	ADV	_	_	_	_	_	_
13	protein	_	VERB	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	LMO	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	regularly	_	ADV	_	_	_	_	_	_
20	coactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
23	acute	_	ADJ	_	Degree=Pos	_	_	_	_
24	lymphoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
25	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	ALL	_	DET	_	_	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	observation	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	likely	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	relate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	findings	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	TAL1	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	LMO	_	PROPN	_	Number=Sing	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	highly	_	ADV	_	_	_	_	_	_
16	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
19	tumorigenesis	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	double	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
24	mice	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	functional	_	ADJ	_	Degree=Pos	_	_	_	_
8	synergy	_	NOUN	_	Number=Sing	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	LMO	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	tumorigenesis	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	tried	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
23	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
24	target	_	NOUN	_	Number=Sing	_	_	_	_
25	genes	_	NOUN	_	Number=Plur	_	_	_	_
26	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	LMO	_	NOUN	_	Number=Sing	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	subtractive	_	ADJ	_	Degree=Pos	_	_	_	_
34	PCR	_	NOUN	_	Number=Sing	_	_	_	_
35	method	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	isolated	_	ADJ	_	Degree=Pos	_	_	_	_
5	genes	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	retinaldehyde	_	ADJ	_	Number=Sing	_	_	_	_
10	dehydrogenase	_	NOUN	_	Number=Sing	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	RALDH2	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	regularly	_	ADV	_	_	_	_	_	_
18	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	most	_	ADJ	_	Degree=Sup	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	T-ALL	_	NOUN	_	Degree=Pos	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	lines	_	NOUN	_	Number=Plur	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	coexpressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	LMO	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Exogenously	_	ADV	_	_	_	_	_	_
2	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	LMO	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	but	_	CCONJ	_	_	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	either	_	ADV	_	_	_	_	_	_
10	alone	_	ADV	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	RALDH2	_	PROPN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	ALL	_	DET	_	_	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	line	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	HPB	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	ALL	_	DET	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	not	_	ADV	_	_	_	_	_	_
28	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
29	endogeneous	_	ADJ	_	Degree=Pos	_	_	_	_
30	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	LMO	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	RALDH2	_	PROPN	_	Number=Sing	_	_	_	_
3	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	T-ALL	_	PROPN	_	Number=Sing	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	however	_	ADV	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	mostly	_	ADV	_	_	_	_	_	_
11	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	within	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
15	intron	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Promoter	_	NOUN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	GATA	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	cryptic	_	ADJ	_	Degree=Pos	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
15	intron	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	essential	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	LMO	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	GATA3	_	ADJ	_	Number=Sing	_	_	_	_
33	binds	_	NOUN	_	Number=Plur	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
36	site	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	forced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	GATA3	_	PROPN	_	Number=Sing	_	_	_	_
8	potentiated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	RALDH2	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	TAL1	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	LMO	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
20	three	_	NUM	_	NumType=Card	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	formed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	complex	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vivo	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	TAL1	_	NOUN	_	Number=Sing	_	_	_	_
5	mutant	_	NOUN	_	Number=Sing	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	DNA	_	PROPN	_	Number=Sing	_	_	_	_
10	also	_	ADV	_	_	_	_	_	_
11	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	RALDH2	_	PROPN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	presence	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	LMO	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	GATA3	_	PROPN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Collectively	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	RALDH2	_	PROPN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
12	example	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	direct	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
16	target	_	NOUN	_	Number=Sing	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	TAL1	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	LMO	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	T-ALL	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	case	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	TAL1	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	LMO	_	PROPN	_	Number=Sing	_	_	_	_
8	act	_	NOUN	_	Number=Sing	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	cofactors	_	NOUN	_	Number=Plur	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	GATA3	_	PROPN	_	Number=Sing	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	RALDH2	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001534	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
5	tissue	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Tissue	_	NOUN	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	TF	_	X	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
13	lineage	_	NOUN	_	Number=Sing	_	_	_	_
14	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	important	_	ADJ	_	Degree=Pos	_	_	_	_
17	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
18	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	initiation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	fibrin	_	NOUN	_	Number=Sing	_	_	_	_
23	deposition	_	NOUN	_	Number=Sing	_	_	_	_
24	at	_	ADP	_	_	_	_	_	_
25	sites	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	extravascular	_	ADJ	_	Degree=Pos	_	_	_	_
28	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	evidence	_	NOUN	_	Number=Sing	_	_	_	_
3	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
8	stress	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	signalling	_	NOUN	_	VerbForm=Ger	_	_	_	_
12	pathway	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	various	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	types	_	NOUN	_	Number=Plur	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	virtue	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	ability	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
24	DNA	_	PROPN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	various	_	ADJ	_	Degree=Pos	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	factors	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	including	_	VERB	_	VerbForm=Ger	_	_	_	_
32	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	kappa	_	NOUN	_	Number=Sing	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	AP	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
5	treatment	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	LPS	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	TF	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	murine	_	ADJ	_	Number=Sing	_	_	_	_
19	peritoneal	_	ADJ	_	Degree=Pos	_	_	_	_
20	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	pyrrolidine	_	VERB	_	Number=Sing	_	_	_	_
3	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
7	scavenger	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	N	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	precursor	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
21	antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
22	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
28	procoagulant	_	ADJ	_	Degree=Pos	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	LPS	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	PROPN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	neither	_	DET	_	_	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	agents	_	NOUN	_	Number=Plur	_	_	_	_
10	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	LPS	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	TF	_	PROPN	_	Number=Sing	_	_	_	_
15	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
16	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	thereby	_	ADV	_	_	_	_	_	_
19	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	effect	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	using	_	VERB	_	VerbForm=Ger	_	_	_	_
7	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
8	anti-TF	_	NOUN	_	Degree=Pos	_	_	_	_
9	antibody	_	NOUN	_	Number=Sing	_	_	_	_
10	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	N-acetyl	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
15	treatment	_	NOUN	_	Number=Sing	_	_	_	_
16	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	characteristic	_	ADJ	_	Degree=Pos	_	_	_	_
19	plasmalemmal	_	ADJ	_	Degree=Pos	_	_	_	_
20	localization	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	TF	_	PROPN	_	Number=Sing	_	_	_	_
23	antigen	_	NOUN	_	Number=Sing	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	response	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	LPS	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	N-acetyl	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
9	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	47	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kD	_	NOUN	_	Number=Sing	_	_	_	_
17	mature	_	NOUN	_	Degree=Pos	_	_	_	_
18	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	LPS	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	finding	_	NOUN	_	Number=Sing	_	_	_	_
27	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	results	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
34	studies	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	conditions	_	NOUN	_	Number=Plur	_	_	_	_
5	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	result	_	VERB	_	VerbForm=Inf	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	less	_	ADJ	_	Degree=Cmp	_	_	_	_
14	mature	_	ADJ	_	Degree=Pos	_	_	_	_
15	forms	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	TF	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	considered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	together	_	ADV	_	_	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	data	_	NOUN	_	Number=Sing	_	_	_	_
7	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
10	exert	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	effects	_	NOUN	_	Number=Plur	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	impairing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	translation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	causing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	degradation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	newly	_	ADV	_	_	_	_	_	_
24	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	tumor	_	NOUN	_	Number=Sing	_	_	_	_
7	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	species	_	NOUN	_	Number=Plur	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	no	_	DET	_	_	_	_	_	_
17	effect	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	LPS	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	tumor	_	NOUN	_	Number=Sing	_	_	_	_
23	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	murine	_	ADJ	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	human	_	ADJ	_	Degree=Pos	_	_	_	_
34	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	TF	_	PROPN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	data	_	NOUN	_	Number=Sing	_	_	_	_
10	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	novel	_	NOUN	_	Number=Sing	_	_	_	_
13	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
14	whereby	_	ADV	_	_	_	_	_	_
15	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
16	agents	_	NOUN	_	Number=Plur	_	_	_	_
17	might	_	AUX	_	VerbForm=Fin	_	_	_	_
18	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
19	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001535	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Natural	_	ADJ	_	Degree=Pos	_	_	_	_
2	variants	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	HIV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	long	_	ADJ	_	Degree=Pos	_	_	_	_
9	terminal	_	NOUN	_	Number=Sing	_	_	_	_
10	repeat	_	NOUN	_	Number=Sing	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	analysis	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	promoters	_	NOUN	_	Number=Plur	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	duplicated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
17	DNA	_	PROPN	_	Number=Sing	_	_	_	_
18	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	motifs	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Sequence	_	NOUN	_	Number=Sing	_	_	_	_
2	variation	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	long	_	ADJ	_	Degree=Pos	_	_	_	_
6	terminal	_	NOUN	_	Number=Sing	_	_	_	_
7	repeat	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	LTR	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	viral	_	ADJ	_	Degree=Pos	_	_	_	_
20	isolates	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	17	_	NUM	_	NumType=Card	_	_	_	_
23	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	individuals	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	classes	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	LTR	_	NOUN	_	Number=Sing	_	_	_	_
5	size	_	NOUN	_	Number=Sing	_	_	_	_
6	variants	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	HIV	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	variant	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	additional	_	ADJ	_	Degree=Pos	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Another	_	DET	_	_	_	_	_	_
2	LTR	_	PROPN	_	Number=Sing	_	_	_	_
3	size	_	NOUN	_	Number=Sing	_	_	_	_
4	variation	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	four	_	NUM	_	NumType=Card	_	_	_	_
9	patients	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	just	_	ADV	_	_	_	_	_	_
14	upstream	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	variation	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	result	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	duplication	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	short	_	ADJ	_	Degree=Pos	_	_	_	_
12	DNA	_	NOUN	_	Number=Sing	_	_	_	_
13	sequence	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	CTG	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	motif	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	culture	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	natural	_	ADJ	_	Degree=Pos	_	_	_	_
8	variant	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	four	_	NUM	_	NumType=Card	_	_	_	_
11	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	slightly	_	ADV	_	_	_	_	_	_
16	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	viral	_	ADJ	_	Degree=Pos	_	_	_	_
21	replication	_	NOUN	_	Number=Sing	_	_	_	_
22	rate	_	NOUN	_	Number=Sing	_	_	_	_
23	than	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	isogenic	_	ADJ	_	Degree=Pos	_	_	_	_
26	control	_	NOUN	_	Number=Sing	_	_	_	_
27	LTR	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	three	_	NUM	_	NumType=Card	_	_	_	_
30	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
31	sites	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	positive	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	duplicated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
7	CTG	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	motif	_	NOUN	_	Number=Sing	_	_	_	_
10	could	_	AUX	_	VerbForm=Fin	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	measure	_	VERB	_	VerbForm=Inf	_	_	_	_
5	small	_	ADJ	_	Degree=Pos	_	_	_	_
6	differences	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	more	_	ADV	_	_	_	_	_	_
11	accurately	_	ADV	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	equal	_	ADJ	_	Degree=Pos	_	_	_	_
14	amounts	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	size	_	NOUN	_	Number=Sing	_	_	_	_
18	variant	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	wild	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	type	_	NOUN	_	Number=Sing	_	_	_	_
24	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
25	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	cotransfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	into	_	ADP	_	_	_	_	_	_
28	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	virus	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	four	_	NUM	_	NumType=Card	_	_	_	_
5	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	outgrow	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	three	_	NUM	_	NumType=Card	_	_	_	_
11	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
12	virus	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	35	_	NUM	_	NumType=Card	_	_	_	_
15	days	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	culture	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	CTG	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	monomer	_	NOUN	_	Number=Sing	_	_	_	_
22	virus	_	NOUN	_	Number=Sing	_	_	_	_
23	outcompeted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	CTG	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	dimer	_	NOUN	_	Number=Sing	_	_	_	_
28	virus	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	42	_	NUM	_	NumType=Card	_	_	_	_
31	days	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	estimate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	SYM	_	_	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	%	_	SYM	_	Number=Sing	_	_	_	_
12	difference	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	production	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	LTR	_	PROPN	_	Number=Sing	_	_	_	_
19	variants	_	NOUN	_	Number=Plur	_	_	_	_
20	when	_	ADV	_	PronType=Int	_	_	_	_
21	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	wild	_	NOUN	_	Degree=Pos	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	type	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001537	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	Nef	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	down	_	ADP	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	regulates	_	VERB	_	Number=Plur	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vitro	_	NOUN	_	Number=Sing	_	_	_	_
27	after	_	ADP	_	_	_	_	_	_
28	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	negative	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	Nef	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
18	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	down	_	ADV	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factors	_	NOUN	_	Number=Plur	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	AP	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	vitro	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	define	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	action	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Nef	_	NOUN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	signal	_	NOUN	_	Number=Sing	_	_	_	_
14	transduction	_	NOUN	_	Number=Sing	_	_	_	_
15	pathways	_	NOUN	_	Number=Plur	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	nef	_	ADJ	_	Degree=Pos	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	tumor	_	NOUN	_	Number=Sing	_	_	_	_
7	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
16	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	similar	_	ADJ	_	Degree=Pos	_	_	_	_
26	level	_	NOUN	_	Number=Sing	_	_	_	_
27	whether	_	SCONJ	_	_	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	not	_	ADV	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	nef	_	ADJ	_	Degree=Pos	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	hand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	TCR	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	CD3	_	PROPN	_	Number=Sing	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	down	_	ADP	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	regulation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
32	factors	_	NOUN	_	Number=Plur	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	AP	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	nef	_	ADJ	_	Degree=Pos	_	_	_	_
46	gene	_	NOUN	_	Number=Sing	_	_	_	_
47	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	with	_	ADP	_	_	_	_	_	_
49	cells	_	NOUN	_	Number=Plur	_	_	_	_
50	not	_	ADV	_	_	_	_	_	_
51	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	nef	_	ADJ	_	Degree=Pos	_	_	_	_
54	gene	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	Nef	_	NOUN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	surface	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	CD3	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	TCR	_	NOUN	_	Number=Sing	_	_	_	_
16	complex	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	Nef	_	NOUN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	down	_	ADV	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	factors	_	NOUN	_	Number=Plur	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	AP	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	T	_	PROPN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	vitro	_	NOUN	_	Number=Sing	_	_	_	_
43	through	_	ADP	_	_	_	_	_	_
44	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
45	effect	_	NOUN	_	Number=Sing	_	_	_	_
46	on	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	TCR	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
51	signal	_	NOUN	_	Number=Sing	_	_	_	_
52	transduction	_	NOUN	_	Number=Sing	_	_	_	_
53	pathway	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001539	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Involvement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cyclic	_	ADJ	_	Degree=Pos	_	_	_	_
4	AMP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	kinases	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	signal	_	ADJ	_	Number=Sing	_	_	_	_
12	transduction	_	NOUN	_	Number=Sing	_	_	_	_
13	pathway	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	highly	_	ADV	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	cyclic	_	ADJ	_	Degree=Pos	_	_	_	_
10	AMP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	kinases	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	that	_	PRON	_	PronType=Rel	_	_	_	_
36	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
37	driven	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	kappa	_	PROPN	_	Number=Sing	_	_	_	_
41	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
42	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
43	or	_	CCONJ	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	human	_	ADJ	_	Degree=Pos	_	_	_	_
46	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
47	virus	_	NOUN	_	Number=Sing	_	_	_	_
48	long	_	ADJ	_	Degree=Pos	_	_	_	_
49	terminal	_	NOUN	_	Number=Sing	_	_	_	_
50	repeat	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
3	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	C	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	VERB	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	cyclic	_	ADJ	_	Degree=Pos	_	_	_	_
17	AMP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	kinases	_	NOUN	_	Number=Plur	_	_	_	_
22	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	involved	_	ADJ	_	Degree=Pos	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	signal	_	ADJ	_	Number=Sing	_	_	_	_
27	transduction	_	NOUN	_	Number=Sing	_	_	_	_
28	pathway	_	NOUN	_	Number=Sing	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	number	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	types	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001540	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	both	_	CCONJ	_	_	_	_	_	_
8	interferon	_	NOUN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	interferon	_	ADJ	_	Degree=Pos	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	by	_	SCONJ	_	_	_	_	_	_
18	suppressing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	tyrosine	_	ADJ	_	Degree=Pos	_	_	_	_
20	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	10	_	NUM	_	NumType=Card	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	helps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	maintain	_	VERB	_	VerbForm=Inf	_	_	_	_
11	polarized	_	VERB	_	Degree=Pos	_	_	_	_
12	T-	_	NOUN	_	_	_	_	_	_
13	helper	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	helper	_	NOUN	_	Number=Sing	_	_	_	_
20	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	Th2	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Part	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	process	_	NOUN	_	Number=Sing	_	_	_	_
5	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	prevention	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	development	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	primary	_	ADJ	_	Degree=Pos	_	_	_	_
19	source	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	interferon	_	NOUN	_	Number=Sing	_	_	_	_
22	gamma	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	potent	_	ADJ	_	Degree=Pos	_	_	_	_
29	activator	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	important	_	ADJ	_	Degree=Pos	_	_	_	_
7	mediators	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Th1	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	type	_	NOUN	_	Number=Sing	_	_	_	_
12	responses	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	such	_	ADJ	_	Degree=Pos	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	hypersensitivity	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
22	sought	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
25	if	_	SCONJ	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	10	_	NUM	_	NumType=Card	_	_	_	_
29	could	_	AUX	_	VerbForm=Fin	_	_	_	_
30	directly	_	ADV	_	_	_	_	_	_
31	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
32	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	IFNalpha	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Highly	_	ADV	_	_	_	_	_	_
2	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	incubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	60	_	NUM	_	NumType=Card	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	90	_	NUM	_	NumType=Card	_	_	_	_
14	minutes	_	NOUN	_	Number=Plur	_	_	_	_
15	before	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	addition	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	IFNalpha	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	preincubation	_	NOUN	_	Number=Sing	_	_	_	_
5	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	several	_	ADJ	_	Degree=Pos	_	_	_	_
14	IFN	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	such	_	ADJ	_	Degree=Pos	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	IP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	10	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	ISG54	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
29	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
30	molecule	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	reduction	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	ability	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	10	_	NUM	_	NumType=Card	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
16	IFN	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	assembly	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	signal	_	NOUN	_	Number=Sing	_	_	_	_
22	transducer	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	activator	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	STAT	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	factors	_	NOUN	_	Number=Plur	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	specific	_	ADJ	_	Degree=Pos	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	motifs	_	NOUN	_	Number=Plur	_	_	_	_
35	on	_	ADP	_	_	_	_	_	_
36	IFNalpha	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
42	genes	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	accomplished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	by	_	SCONJ	_	_	_	_	_	_
5	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
11	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	component	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	IFNalpha	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	DNA	_	PROPN	_	Number=Sing	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	complexes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	10	_	NUM	_	NumType=Card	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	directly	_	ADV	_	_	_	_	_	_
8	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
9	STAT	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	early	_	ADJ	_	Degree=Pos	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	IFNalpha	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	by	_	SCONJ	_	_	_	_	_	_
25	suppressing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
28	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
4	through	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	ability	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
21	signaling	_	NOUN	_	Number=Sing	_	_	_	_
22	3	_	NUM	_	NumType=Card	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	SOCS3	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001542	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Okadaic	_	PROPN	_	Number=Sing	_	_	_	_
2	acid	_	PROPN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	potent	_	ADJ	_	Degree=Pos	_	_	_	_
6	inducer	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	AP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	tumor	_	NOUN	_	Number=Sing	_	_	_	_
19	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
9	concentration	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
12	acid	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	2A	_	NUM	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	induction	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	AP	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	increase	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappa	_	NOUN	_	Number=Sing	_	_	_	_
42	B	_	NOUN	_	Number=Sing	_	_	_	_
43	levels	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	no	_	DET	_	_	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	octamer	_	NOUN	_	Number=Sing	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	Oct	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	Oct	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	SYM	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	ADP	_	_	_	_	_	_
2	both	_	CCONJ	_	_	_	_	_	_
3	AP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	important	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	tumor	_	NOUN	_	Number=Sing	_	_	_	_
23	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	TNF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
34	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	effects	_	NOUN	_	Number=Plur	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	okadaic	_	PROPN	_	Number=Sing	_	_	_	_
39	acid	_	NOUN	_	Number=Sing	_	_	_	_
40	on	_	ADP	_	_	_	_	_	_
41	TNF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	alpha	_	PROPN	_	Number=Sing	_	_	_	_
44	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
45	levels	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
4	acid	_	NOUN	_	Number=Sing	_	_	_	_
5	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	striking	_	NOUN	_	Degree=Pos	_	_	_	_
9	increase	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
16	within	_	ADP	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	h	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	large	_	ADJ	_	Degree=Pos	_	_	_	_
23	amounts	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	TNF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	released	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	into	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	culture	_	NOUN	_	Number=Sing	_	_	_	_
33	media	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
3	acid	_	PROPN	_	Number=Sing	_	_	_	_
4	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	potent	_	NOUN	_	Degree=Pos	_	_	_	_
7	inductive	_	ADJ	_	Degree=Pos	_	_	_	_
8	signal	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	_	_	_	_	_
18	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
19	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
22	either	_	CCONJ	_	_	_	_	_	_
23	B	_	DET	_	Degree=Pos	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
28	secretion	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001543	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Long	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	term	_	NOUN	_	Number=Sing	_	_	_	_
4	inositol	_	NOUN	_	Number=Sing	_	_	_	_
5	phosphate	_	NOUN	_	Number=Sing	_	_	_	_
6	release	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	not	_	ADV	_	_	_	_	_	_
10	tyrosine	_	VERB	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	secretion	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	AT	_	ADP	_	_	_	_	_	_
24	induction	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	anti-CD3	_	ADJ	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	activated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
29	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cascade	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	events	_	NOUN	_	Number=Plur	_	_	_	_
5	within	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
8	few	_	ADJ	_	Degree=Pos	_	_	_	_
9	minutes	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	well	_	ADV	_	Degree=Pos	_	_	_	_
17	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	many	_	ADJ	_	Degree=Pos	_	_	_	_
3	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
4	messengers	_	NOUN	_	Number=Plur	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	number	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	model	_	NOUN	_	Number=Sing	_	_	_	_
22	systems	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	rate	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	limiting	_	NOUN	_	VerbForm=Ger	_	_	_	_
28	step	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
36	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	To	_	ADP	_	_	_	_	_	_
2	model	_	NOUN	_	Number=Sing	_	_	_	_
3	effective	_	ADJ	_	Degree=Pos	_	_	_	_
4	versus	_	ADP	_	_	_	_	_	_
5	ineffective	_	ADJ	_	Degree=Pos	_	_	_	_
6	CD3	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
9	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	anti-CD3	_	ADJ	_	Degree=Pos	_	_	_	_
19	mAbs	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	ability	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	:	_	PUNCT	_	_	_	_	_	_

1	OKT3	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	which	_	PRON	_	PronType=Rel	_	_	_	_
4	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	early	_	ADJ	_	Degree=Pos	_	_	_	_
6	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	messenger	_	NOUN	_	Number=Sing	_	_	_	_
8	generation	_	NOUN	_	Number=Sing	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	unable	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	without	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
19	signal	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	64.1	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	T	_	DET	_	Number=Sing	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	own	_	ADJ	_	Degree=Pos	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	similar	_	ADJ	_	Degree=Pos	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	mAbs	_	NOUN	_	Number=Plur	_	_	_	_
12	over	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	period	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	hours	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	inositol	_	NOUN	_	Number=Sing	_	_	_	_
5	phosphate	_	NOUN	_	Number=Sing	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	stronger	_	ADJ	_	Degree=Cmp	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	64.1	_	NUM	_	NumType=Card	_	_	_	_
11	than	_	ADP	_	_	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	OKT3	_	PROPN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	tie	_	VERB	_	VerbForm=Inf	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	events	_	NOUN	_	Number=Plur	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	gene	_	VERB	_	VerbForm=Inf	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	measured	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	PROPN	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	AT	_	ADP	_	_	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
23	after	_	ADP	_	_	_	_	_	_
24	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
25	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
3	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	appearance	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	components	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	c	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	Rel	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	p65	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	RelA	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	p50	_	PROPN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B1	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	PROPN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	DNA	_	NOUN	_	Number=Sing	_	_	_	_
38	binding	_	VERB	_	Number=Sing	_	_	_	_
39	activity	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	only	_	ADV	_	_	_	_	_	_
4	64.1	_	NUM	_	NumType=Card	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	AT	_	ADP	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	correlating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	ability	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	AT	_	ADP	_	_	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	secretion	_	NOUN	_	Number=Sing	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	levels	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	inositol	_	NOUN	_	Number=Sing	_	_	_	_
19	phosphate	_	NOUN	_	Number=Sing	_	_	_	_
20	release	_	NOUN	_	Number=Sing	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	not	_	ADV	_	_	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	gross	_	ADJ	_	Degree=Pos	_	_	_	_
25	levels	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	tyrosine	_	ADJ	_	Number=Sing	_	_	_	_
28	kinase	_	NOUN	_	Number=Sing	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	late	_	ADV	_	Degree=Pos	_	_	_	_
32	following	_	VERB	_	VerbForm=Ger	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	response	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	hand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	PROPN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	even	_	ADV	_	_	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	smaller	_	ADJ	_	Degree=Cmp	_	_	_	_
22	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
23	messenger	_	NOUN	_	Number=Sing	_	_	_	_
24	response	_	NOUN	_	Number=Sing	_	_	_	_
25	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	OKT3	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001555	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differentiation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	helper	_	NOUN	_	Number=Sing	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	:	_	PUNCT	_	_	_	_	_	_
8	selective	_	ADJ	_	Degree=Pos	_	_	_	_
9	regulation	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	members	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	STAT	_	PROPN	_	Number=Sing	_	_	_	_
15	family	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-4	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	4	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	12	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	12	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	control	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	helper	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	summarize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	investigate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
13	selectively	_	ADV	_	_	_	_	_	_
14	reprogramme	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T-lymphocytes	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Cytokine	_	PROPN	_	Number=Sing	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
10	residues	_	NOUN	_	Number=Plur	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
14	domain	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
18	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	phosphotyrosines	_	NOUN	_	Number=Plur	_	_	_	_
3	serve	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	docking	_	NOUN	_	Number=Sing	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	latent	_	ADJ	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	signal	_	NOUN	_	Number=Sing	_	_	_	_
16	transducers	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	activators	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	Stat	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	proteins	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Receptor	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	Stat	_	PROPN	_	Number=Sing	_	_	_	_
4	interaction	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	src	_	NOUN	_	Number=Sing	_	_	_	_
10	homology	_	NOUN	_	Number=Sing	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	SH2	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	domain	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
19	Stat	_	PROPN	_	Number=Sing	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	Stat	_	PROPN	_	Number=Sing	_	_	_	_
3	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	domain	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	strongly	_	ADV	_	_	_	_	_	_
13	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	phosphotyrosine	_	NOUN	_	Number=Sing	_	_	_	_
17	residue	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_

1	Stat	_	PROPN	_	Number=Sing	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	dictated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	amino	_	NOUN	_	Number=Sing	_	_	_	_
7	acid	_	NOUN	_	Number=Sing	_	_	_	_
8	residues	_	NOUN	_	Number=Plur	_	_	_	_
9	C	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	terminal	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	phosphotyrosine	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Specific	_	ADJ	_	Degree=Pos	_	_	_	_
2	docking	_	NOUN	_	Number=Sing	_	_	_	_
3	sites	_	NOUN	_	Number=Plur	_	_	_	_
4	within	_	ADP	_	_	_	_	_	_
5	individual	_	ADJ	_	Degree=Pos	_	_	_	_
6	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
7	receptors	_	NOUN	_	Number=Plur	_	_	_	_
8	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	almost	_	ADV	_	_	_	_	_	_
13	all	_	DET	_	_	_	_	_	_
14	Stat	_	PROPN	_	Number=Sing	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	direct	_	ADJ	_	Degree=Pos	_	_	_	_
3	coupling	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	helps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
13	how	_	ADV	_	PronType=Int	_	_	_	_
14	different	_	ADJ	_	Degree=Pos	_	_	_	_
15	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
16	elicit	_	VERB	_	Degree=Pos	_	_	_	_
17	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
18	patterns	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001556	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Function	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	Rel	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	sites	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	major	_	ADJ	_	Degree=Pos	_	_	_	_
9	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
10	complex	_	NOUN	_	Number=Sing	_	_	_	_
11	class	_	NOUN	_	Number=Sing	_	_	_	_
12	II	_	NUM	_	NumType=Card	_	_	_	_
13	invariant	_	ADJ	_	Degree=Pos	_	_	_	_
14	chain	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	specific	_	ADJ	_	Degree=Pos	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	different	_	ADJ	_	Degree=Pos	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	Rel	_	NOUN	_	Number=Sing	_	_	_	_
31	subunits	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	promoter	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	major	_	ADJ	_	Degree=Pos	_	_	_	_
7	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
8	complex	_	NOUN	_	Number=Sing	_	_	_	_
9	class	_	NOUN	_	Number=Sing	_	_	_	_
10	II	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	invariant	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	chain	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	Ii	_	X	_	_	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	two	_	NUM	_	NumType=Card	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	Rel	_	NOUN	_	Number=Sing	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	sites	_	NOUN	_	Number=Plur	_	_	_	_
30	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	at	_	ADP	_	_	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	109	_	NUM	_	NumType=Card	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	-	_	SYM	_	_	_	_	_	_
36	118	_	NUM	_	NumType=Card	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	Ii	_	NUM	_	NumType=Card	_	_	_	_
39	kappa	_	NOUN	_	Number=Sing	_	_	_	_
40	B	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	163	_	NUM	_	NumType=Card	_	_	_	_
47	to	_	ADP	_	_	_	_	_	_
48	-	_	SYM	_	_	_	_	_	_
49	172	_	NUM	_	NumType=Card	_	_	_	_
50	(	_	PUNCT	_	_	_	_	_	_
51	Ii	_	NUM	_	NumType=Card	_	_	_	_
52	kappa	_	NOUN	_	Number=Sing	_	_	_	_
53	B	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	2	_	X	_	NumType=Card	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	from	_	ADP	_	_	_	_	_	_
58	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
59	transcription	_	NOUN	_	Number=Sing	_	_	_	_
60	start	_	NOUN	_	Number=Sing	_	_	_	_
61	site	_	NOUN	_	Number=Sing	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	differential	_	ADJ	_	Degree=Pos	_	_	_	_
7	function	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	each	_	DET	_	_	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	Rel	_	NOUN	_	Number=Sing	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	several	_	ADJ	_	Degree=Pos	_	_	_	_
21	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	types	_	NOUN	_	Number=Plur	_	_	_	_
24	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	specific	_	ADJ	_	Degree=Pos	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	/	_	PUNCT	_	_	_	_	_	_
36	Rel	_	NOUN	_	Number=Sing	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	factors	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Ii	_	PROPN	_	Number=Sing	_	_	_	_
2	kappa	_	NOUN	_	Number=Sing	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	positive	_	ADJ	_	Degree=Pos	_	_	_	_
9	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	lines	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	Ii-expressing	_	ADJ	_	Degree=Pos	_	_	_	_
20	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
21	line	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	H9	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	negative	_	ADJ	_	Degree=Pos	_	_	_	_
30	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	element	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	myelomonocytic	_	ADJ	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	glia	_	NOUN	_	Number=Sing	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	lines	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	DNA	_	NOUN	_	Number=Sing	_	_	_	_
6	contacts	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	Ii	_	NUM	_	NumType=Card	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	lines	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	functional	_	ADJ	_	Degree=Pos	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	either	_	CCONJ	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	positive	_	ADJ	_	Degree=Pos	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	negative	_	ADJ	_	Degree=Pos	_	_	_	_
30	regulator	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	supershift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	determine	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	members	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	Rel	_	NOUN	_	Number=Sing	_	_	_	_
16	family	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factors	_	NOUN	_	Number=Plur	_	_	_	_
20	can	_	AUX	_	VerbForm=Fin	_	_	_	_
21	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vitro	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	DNA	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	binding	_	NOUN	_	Number=Sing	_	_	_	_
32	complexes	_	NOUN	_	Number=Plur	_	_	_	_
33	that	_	PRON	_	PronType=Rel	_	_	_	_
34	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	p50	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	p52	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	p65	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	cRel	_	NOUN	_	Number=Sing	_	_	_	_
43	correlate	_	VERB	_	Degree=Pos	_	_	_	_
44	with	_	ADP	_	_	_	_	_	_
45	positive	_	ADJ	_	Degree=Pos	_	_	_	_
46	regulation	_	NOUN	_	Number=Sing	_	_	_	_
47	whereas	_	SCONJ	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	presence	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	p50	_	NOUN	_	Number=Sing	_	_	_	_
52	correlates	_	VERB	_	Number=Plur	_	_	_	_
53	with	_	ADP	_	_	_	_	_	_
54	negative	_	ADJ	_	Degree=Pos	_	_	_	_
55	regulation	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Ii	_	PROPN	_	_	_	_	_	_
2	kappa	_	NOUN	_	Number=Sing	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	positive	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	lines	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	negative	_	ADJ	_	Degree=Pos	_	_	_	_
22	regulation	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	H9	_	NUM	_	NumType=Card	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	myelomonocytic	_	ADJ	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	glial	_	ADJ	_	Degree=Pos	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	lines	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	ADJ	_	Degree=Pos	_	_	_	_
3	occupancy	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	only	_	ADV	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	H9	_	PROPN	_	Number=Sing	_	_	_	_
13	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
14	line	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Again	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vitro	_	PROPN	_	Number=Sing	_	_	_	_
5	supershift	_	NOUN	_	Number=Sing	_	_	_	_
6	studies	_	NOUN	_	Number=Plur	_	_	_	_
7	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	presence	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	p50	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	p52	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	p65	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	cRel	_	NOUN	_	Number=Sing	_	_	_	_
20	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	positive	_	ADJ	_	Degree=Pos	_	_	_	_
23	function	_	NOUN	_	Number=Sing	_	_	_	_
24	whereas	_	SCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	presence	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	only	_	ADV	_	_	_	_	_	_
29	p50	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	p52	_	NOUN	_	Number=Sing	_	_	_	_
32	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	negative	_	ADJ	_	Degree=Pos	_	_	_	_
35	function	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	differential	_	ADJ	_	Degree=Pos	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	NF	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_

1	B	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	Rel	_	NOUN	_	Number=Sing	_	_	_	_
4	subunits	_	NOUN	_	Number=Plur	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	likely	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	disparate	_	ADJ	_	Degree=Pos	_	_	_	_
11	functions	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	two	_	NUM	_	NumType=Card	_	_	_	_
15	NF	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	Rel	_	NOUN	_	Number=Sing	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	sites	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001557	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	relA	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	p65	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	kappa	_	VERB	_	Number=Sing	_	_	_	_
10	B	_	ADJ	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	subunit	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	during	_	ADP	_	_	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
19	blood	_	NOUN	_	Number=Sing	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	evaluated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	DNA	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	subunits	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
22	blood	_	NOUN	_	Number=Sing	_	_	_	_
23	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	MDMs	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	DNA	_	NOUN	_	Number=Sing	_	_	_	_
3	binding	_	VERB	_	Number=Sing	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	consisting	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	p50	_	NUM	_	NumType=Card	_	_	_	_
8	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	extracts	_	NOUN	_	Number=Plur	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	both	_	DET	_	_	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	types	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	additional	_	ADJ	_	Degree=Pos	_	_	_	_
3	complex	_	NOUN	_	Number=Sing	_	_	_	_
4	composed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	p50/RelA	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	p65	_	NUM	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
11	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	only	_	ADV	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	extracts	_	NOUN	_	Number=Plur	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	7	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	day	_	NOUN	_	Number=Sing	_	_	_	_
20	MDMs	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Immunoblot	_	PROPN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	p50	_	PROPN	_	Number=Sing	_	_	_	_
7	subunit	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	constitutively	_	ADV	_	_	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	MDMs	_	PROPN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	RelA	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	p65	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	subunit	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	barely	_	ADV	_	_	_	_	_	_
12	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	level	_	NOUN	_	Number=Sing	_	_	_	_
19	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	markedly	_	ADV	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	MDMs	_	PROPN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	RelA	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	p65	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
8	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	stability	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	RelA	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	p65	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	significantly	_	ADV	_	_	_	_	_	_
20	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	MDMs	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	MDMs	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	kappa	_	VERB	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADV	_	_	_	_	_	_
13	well	_	ADV	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	appearance	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	novel	_	NOUN	_	Number=Sing	_	_	_	_
20	M	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	r	_	X	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	40,000	_	NUM	_	NumType=Card	_	_	_	_
25	form	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
28	kappa	_	PROPN	_	Number=Sing	_	_	_	_
29	B	_	PROPN	_	Number=Sing	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	also	_	ADV	_	_	_	_	_	_
33	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
6	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
7	results	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	active	_	ADJ	_	Degree=Pos	_	_	_	_
13	p50	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	RelA	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	p65	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	capacity	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
25	target	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	parallel	_	ADJ	_	Degree=Pos	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	kappa	_	VERB	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	allow	_	VERB	_	VerbForm=Inf	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	continuous	_	ADJ	_	Degree=Pos	_	_	_	_
15	presence	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
19	reservoir	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	p50/RelA	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	p65	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	complexes	_	NOUN	_	Number=Plur	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	readily	_	ADV	_	_	_	_	_	_
29	available	_	ADJ	_	Degree=Pos	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	inducer	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
34	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001558	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CholecystokininB	_	ADJ	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
6	lymphoblastic	_	ADJ	_	Number=Sing	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	involved	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	activator	_	NOUN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	aim	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	cholecystokinin	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	CCK	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	B	_	X	_	_	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	lymphoblastic	_	ADJ	_	Number=Sing	_	_	_	_
23	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	trophic	_	ADJ	_	Degree=Pos	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	such	_	DET	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	using	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	reporter	_	NOUN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	strategy	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	purpose	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	transiently	_	ADV	_	_	_	_	_	_
7	transfected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	reporter	_	NOUN	_	Number=Sing	_	_	_	_
14	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
15	p	_	NOUN	_	Number=Sing	_	_	_	_
16	[	_	PUNCT	_	_	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	TRE	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	tk	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	Luc	_	PROPN	_	Number=Sing	_	_	_	_
25	]	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	CCK	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	8	_	NUM	_	NumType=Card	_	_	_	_
32	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
33	able	_	ADJ	_	Degree=Pos	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	dose	_	VERB	_	VerbForm=Inf	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	dependently	_	ADV	_	_	_	_	_	_
38	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
39	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
40	expression	_	NOUN	_	Number=Sing	_	_	_	_
41	related	_	ADJ	_	Degree=Pos	_	_	_	_
42	to	_	ADP	_	_	_	_	_	_
43	activator	_	NOUN	_	Number=Sing	_	_	_	_
44	protein	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	AP	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	1	_	NUM	_	NumType=Card	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	activation	_	NOUN	_	Number=Sing	_	_	_	_
53	with	_	ADP	_	_	_	_	_	_
54	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
55	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
56	response	_	NOUN	_	Number=Sing	_	_	_	_
57	identical	_	ADJ	_	Degree=Pos	_	_	_	_
58	to	_	ADP	_	_	_	_	_	_
59	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
60	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
61	with	_	ADP	_	_	_	_	_	_
62	compounds	_	NOUN	_	Number=Plur	_	_	_	_
63	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
64	to	_	PART	_	_	_	_	_	_
65	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
66	AP	_	NOUN	_	Number=Sing	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	1	_	NUM	_	NumType=Card	_	_	_	_
69	complex	_	NOUN	_	Number=Sing	_	_	_	_
70	(	_	PUNCT	_	_	_	_	_	_
71	quantitatively	_	ADV	_	_	_	_	_	_
72	,	_	PUNCT	_	_	_	_	_	_
73	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
74	same	_	ADJ	_	Degree=Pos	_	_	_	_
75	level	_	NOUN	_	Number=Sing	_	_	_	_
76	of	_	ADP	_	_	_	_	_	_
77	induction	_	NOUN	_	Number=Sing	_	_	_	_
78	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
79	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
80	with	_	ADP	_	_	_	_	_	_
81	1	_	NUM	_	NumType=Card	_	_	_	_
82	nM	_	NOUN	_	Number=Sing	_	_	_	_
83	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
84	-	_	PUNCT	_	_	_	_	_	_
85	13	_	NUM	_	NumType=Card	_	_	_	_
86	-	_	PUNCT	_	_	_	_	_	_
87	acetate	_	NOUN	_	Number=Sing	_	_	_	_
88	,	_	PUNCT	_	_	_	_	_	_
89	100	_	NUM	_	NumType=Card	_	_	_	_
90	microM	_	NUM	_	Number=Sing	_	_	_	_
91	diacylglycerol	_	NOUN	_	Number=Sing	_	_	_	_
92	,	_	PUNCT	_	_	_	_	_	_
93	or	_	CCONJ	_	_	_	_	_	_
94	4	_	NUM	_	NumType=Card	_	_	_	_
95	nM	_	NOUN	_	Degree=Pos	_	_	_	_
96	epidermal	_	ADJ	_	Degree=Pos	_	_	_	_
97	growth	_	NOUN	_	Number=Sing	_	_	_	_
98	factor	_	NOUN	_	Number=Sing	_	_	_	_
99	)	_	PUNCT	_	_	_	_	_	_
100	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	involvement	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	CCK	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	B	_	X	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	such	_	DET	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	effect	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	selective	_	ADJ	_	Degree=Pos	_	_	_	_
23	CCK	_	PROPN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	B	_	X	_	_	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
29	PD	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	135,158	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	COS	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	7	_	NUM	_	NumType=Card	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	CCK	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	B	_	X	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
23	T	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	better	_	ADV	_	Degree=Cmp	_	_	_	_
3	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	AP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
18	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	two	_	NUM	_	NumType=Card	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	serine	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	threonine	_	NOUN	_	Number=Sing	_	_	_	_
26	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2A	_	NUM	_	Number=Sing	_	_	_	_
32	:	_	PUNCT	_	_	_	_	_	_
33	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
34	acid	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	calyculin	_	PROPN	_	Number=Sing	_	_	_	_
37	A	_	PROPN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	compounds	_	NOUN	_	Number=Plur	_	_	_	_
3	strongly	_	ADV	_	_	_	_	_	_
4	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	12	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	myristate	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	13	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	acetate	_	ADJ	_	Degree=Pos	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	whereas	_	SCONJ	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	contribution	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
26	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	CCK	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	8	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
35	activity	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	confirm	_	VERB	_	VerbForm=Inf	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	CCK	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	B	_	X	_	_	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	receptors	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	involved	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	AP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
18	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	CCK	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	8	_	NUM	_	NumType=Card	_	_	_	_
23	effect	_	NOUN	_	Number=Sing	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	natural	_	ADJ	_	Degree=Pos	_	_	_	_
32	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	several	_	ADJ	_	Degree=Pos	_	_	_	_
37	factors	_	NOUN	_	Number=Plur	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	including	_	VERB	_	VerbForm=Ger	_	_	_	_
40	AP	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_
44	In	_	ADP	_	_	_	_	_	_
45	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
46	T	_	PROPN	_	Number=Sing	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	by	_	ADP	_	_	_	_	_	_
50	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	12	_	NUM	_	NumType=Card	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	myristate	_	NOUN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	13	_	NUM	_	NumType=Card	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	acetate	_	NOUN	_	Number=Sing	_	_	_	_
59	and	_	CCONJ	_	_	_	_	_	_
60	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
61	,	_	PUNCT	_	_	_	_	_	_
62	CCK	_	PROPN	_	Number=Sing	_	_	_	_
63	-	_	PUNCT	_	_	_	_	_	_
64	8	_	NUM	_	NumType=Card	_	_	_	_
65	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
66	IL	_	PROPN	_	Number=Sing	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	2	_	NUM	_	NumType=Card	_	_	_	_
69	expression	_	NOUN	_	Number=Sing	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	PD	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	135,158	_	NUM	_	NumType=Card	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CCK	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	8	_	NUM	_	NumType=Card	_	_	_	_
8	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	trophic	_	ADJ	_	Degree=Pos	_	_	_	_
11	effect	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	CCK	_	PROPN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	B	_	NOUN	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	receptors	_	NOUN	_	Number=Plur	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	modulation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	AP	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	regulated	_	VERB	_	Degree=Pos	_	_	_	_
34	genes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001565	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Phosphatidylinositides	_	NOUN	_	Number=Plur	_	_	_	_
2	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	plasma	_	VERB	_	Number=Sing	_	_	_	_
5	membrane	_	NOUN	_	Number=Sing	_	_	_	_
6	CD14	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
10	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
14	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
3	lipopolysaccharides	_	NOUN	_	Number=Plur	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	LPS	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	several	_	ADJ	_	Degree=Pos	_	_	_	_
9	other	_	ADJ	_	Degree=Pos	_	_	_	_
10	microbial	_	ADJ	_	Degree=Pos	_	_	_	_
11	agonists	_	NOUN	_	Number=Plur	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	mCD14	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	membrane	_	NOUN	_	Number=Sing	_	_	_	_
18	CD14	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	surface	_	NOUN	_	Number=Sing	_	_	_	_
25	receptor	_	NOUN	_	Number=Sing	_	_	_	_
26	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	principally	_	ADV	_	_	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	host	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	mCD14	_	NOUN	_	Number=Sing	_	_	_	_
37	ligands	_	NOUN	_	Number=Plur	_	_	_	_
38	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	poorly	_	ADV	_	_	_	_	_	_
40	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	phosphatidylinositol	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	PtdIns	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	phosphatidylinositol	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	phosphate	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	other	_	ADJ	_	Degree=Pos	_	_	_	_
18	phosphatidylinositides	_	NOUN	_	Number=Plur	_	_	_	_
19	can	_	AUX	_	VerbForm=Fin	_	_	_	_
20	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	mCD14	_	PROPN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Phosphatidylserine	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	PS	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	another	_	DET	_	_	_	_	_	_
7	anionic	_	ADJ	_	Degree=Pos	_	_	_	_
8	glycerophospholipid	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	mCD14	_	VERB	_	VerbForm=Inf	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
15	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
16	affinity	_	NOUN	_	Number=Sing	_	_	_	_
17	than	_	SCONJ	_	_	_	_	_	_
18	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	PtdIns	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	binding	_	VERB	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	lipid	_	ADJ	_	Degree=Pos	_	_	_	_
8	transfer	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	serum	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	facilitates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	PS	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	PtdIns	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mCD14	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	PtdIns	_	PROPN	_	Number=Sing	_	_	_	_
2	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	mCD14	_	PROPN	_	Number=Sing	_	_	_	_
5	can	_	AUX	_	VerbForm=Fin	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	anti-CD14	_	ADJ	_	NumType=Card	_	_	_	_
10	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
11	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	LPS	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	mCD14	_	NOUN	_	Number=Sing	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	PtdIns	_	NOUN	_	Number=Plur	_	_	_	_
21	can	_	AUX	_	VerbForm=Fin	_	_	_	_
22	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
23	both	_	CCONJ	_	_	_	_	_	_
24	LPS	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	mCD14	_	NOUN	_	Number=Sing	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	LPS	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	responses	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Serum	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	equilibrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	PtdIns	_	PROPN	_	Number=Plur	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	mCD14	_	NUM	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	raising	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	possibility	_	NOUN	_	Number=Sing	_	_	_	_
16	that	_	SCONJ	_	PronType=Rel	_	_	_	_
17	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
18	PtdIns	_	PROPN	_	Number=Plur	_	_	_	_
19	may	_	AUX	_	VerbForm=Fin	_	_	_	_
20	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	responses	_	NOUN	_	Number=Plur	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	LPS	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	other	_	ADJ	_	Degree=Pos	_	_	_	_
27	mCD14	_	ADJ	_	Number=Sing	_	_	_	_
28	ligands	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	vivo	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001581	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	pyruvate	_	ADJ	_	Degree=Pos	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Mammal	_	ADJ	_	Number=Sing	_	_	_	_
2	pyruvate	_	NOUN	_	Degree=Pos	_	_	_	_
3	kinases	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	encoded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	L	_	PROPN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	produces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	R	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	PK	_	X	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	hepatic	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	L	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	PK	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	isozymes	_	NOUN	_	Number=Plur	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
24	use	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	two	_	NUM	_	NumType=Card	_	_	_	_
27	promoters	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	characterization	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cis	_	NOUN	_	Number=Plur	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	trans	_	NOUN	_	Number=Plur	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	elements	_	NOUN	_	Number=Plur	_	_	_	_
14	involved	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	tissue	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	L	_	PROPN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	R-PK	_	NOUN	_	Number=Sing	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	fragment	_	NOUN	_	Number=Sing	_	_	_	_
5	extending	_	VERB	_	VerbForm=Ger	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	870	_	NUM	_	NumType=Card	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_
11	54	_	NUM	_	NumType=Card	_	_	_	_
12	relative	_	ADV	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cap	_	NOUN	_	Number=Sing	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
19	specificity	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	reporter	_	NOUN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Within	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	define	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	62	_	NUM	_	NumType=Card	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	+	_	SYM	_	_	_	_	_	_
15	54	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	displays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	erythroid	_	VERB	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	specific	_	ADJ	_	Degree=Pos	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	two	_	NUM	_	NumType=Card	_	_	_	_
26	DNA	_	NOUN	_	Number=Sing	_	_	_	_
27	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
28	sites	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	at	_	ADP	_	_	_	_	_	_
5	-	_	SYM	_	_	_	_	_	_
6	50	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	binds	_	NOUN	_	Number=Plur	_	_	_	_
9	members	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	CCACC	_	PROPN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
15	family	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	-	_	SYM	_	_	_	_	_	_
23	20	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	GATA	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	20	_	NUM	_	NumType=Card	_	_	_	_
5	GATA	_	PROPN	_	Number=Sing	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	AGATAA	_	PROPN	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	potential	_	ADJ	_	Degree=Pos	_	_	_	_
15	TFIID	_	PROPN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	site	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
20	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
23	TFIID	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	substitution	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	GATA	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	canonical	_	ADJ	_	Degree=Pos	_	_	_	_
13	TFIID	_	PROPN	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	deletions	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	both	_	DET	_	_	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	only	_	ADV	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	association	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	CCACC	_	PROPN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	GATA	_	PROPN	_	Number=Sing	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	sites	_	NOUN	_	Number=Plur	_	_	_	_
20	can	_	AUX	_	VerbForm=Fin	_	_	_	_
21	drive	_	VERB	_	VerbForm=Inf	_	_	_	_
22	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	tissue	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	R-PK	_	NOUN	_	Number=Sing	_	_	_	_
31	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
32	promoter	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	co-transfection	_	NOUN	_	Number=Sing	_	_	_	_
5	experiments	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	study	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	elements	_	NOUN	_	Number=Plur	_	_	_	_
11	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	hGATA	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	R-PK	_	NOUN	_	Number=Sing	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001585	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	peri-kappa	_	NOUN	_	Number=Sing	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	site	_	NOUN	_	Number=Sing	_	_	_	_
5	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	like	_	ADP	_	_	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
24	cases	_	NOUN	_	Number=Plur	_	_	_	_
25	primarily	_	ADV	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	West	_	PROPN	_	Number=Sing	_	_	_	_
28	Africa	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	display	_	VERB	_	Number=Sing	_	_	_	_
9	significant	_	ADJ	_	Degree=Pos	_	_	_	_
10	differences	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	nucleic	_	ADJ	_	Degree=Pos	_	_	_	_
13	acid	_	NOUN	_	Number=Sing	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	natural	_	ADJ	_	Degree=Pos	_	_	_	_
19	history	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
22	disease	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	differences	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	previously	_	ADV	_	_	_	_	_	_
9	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	functions	_	NOUN	_	Number=Plur	_	_	_	_
21	quite	_	ADV	_	_	_	_	_	_
22	differently	_	ADV	_	_	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	HIV	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
9	following	_	VERB	_	VerbForm=Ger	_	_	_	_
10	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
11	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	largely	_	ADV	_	_	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	two	_	NUM	_	NumType=Card	_	_	_	_
27	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	sites	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	HIV	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	long	_	ADJ	_	Degree=Pos	_	_	_	_
37	terminal	_	NOUN	_	Number=Sing	_	_	_	_
38	repeat	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	HIV	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	2	_	NUM	_	NumType=Card	_	_	_	_
46	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	T	_	NOUN	_	Number=Sing	_	_	_	_
51	cells	_	NOUN	_	Number=Plur	_	_	_	_
52	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
53	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
54	on	_	ADP	_	_	_	_	_	_
55	four	_	NUM	_	NumType=Card	_	_	_	_
56	cis	_	NOUN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	acting	_	NOUN	_	Number=Sing	_	_	_	_
59	elements	_	NOUN	_	Number=Plur	_	_	_	_
60	:	_	PUNCT	_	_	_	_	_	_

1	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	single	_	ADJ	_	Degree=Pos	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	purine	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	rich	_	ADJ	_	Degree=Pos	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	PuB1	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	PuB2	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	pets	_	NOUN	_	Number=Plur	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	now	_	ADV	_	_	_	_	_	_
4	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	novel	_	NOUN	_	Number=Sing	_	_	_	_
7	cis	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	immediately	_	ADV	_	_	_	_	_	_
19	upstream	_	ADV	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	kappa	_	PROPN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	peri-kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	site	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	conserved	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	among	_	ADP	_	_	_	_	_	_
6	isolates	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	closely	_	ADV	_	_	_	_	_	_
14	related	_	ADJ	_	Degree=Pos	_	_	_	_
15	simian	_	ADJ	_	Degree=Pos	_	_	_	_
16	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	transfection	_	NOUN	_	Number=Sing	_	_	_	_
21	assays	_	NOUN	_	Number=Plur	_	_	_	_
22	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	HIV	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	following	_	VERB	_	VerbForm=Ger	_	_	_	_
33	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
36	but	_	CCONJ	_	_	_	_	_	_
37	not	_	ADV	_	_	_	_	_	_
38	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
39	lines	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
5	description	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	displays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	such	_	ADJ	_	Degree=Pos	_	_	_	_
16	monocyte	_	ADJ	_	Degree=Pos	_	_	_	_
17	specificity	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	no	_	DET	_	_	_	_	_	_
21	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
22	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
23	element	_	NOUN	_	Number=Sing	_	_	_	_
24	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	clearly	_	ADV	_	_	_	_	_	_
27	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	HIV	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	s	_	X	_	_	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
11	blood	_	NOUN	_	Number=Sing	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	peri-kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
23	mobility	_	NOUN	_	Number=Sing	_	_	_	_
24	shift	_	NOUN	_	Number=Sing	_	_	_	_
25	assays	_	NOUN	_	Number=Plur	_	_	_	_
26	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	either	_	CCONJ	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	different	_	ADJ	_	Degree=Pos	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	binds	_	NOUN	_	Number=Plur	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
35	site	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
38	versus	_	ADP	_	_	_	_	_	_
39	T	_	NOUN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	or	_	CCONJ	_	_	_	_	_	_
42	that	_	SCONJ	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	protein	_	NOUN	_	Number=Sing	_	_	_	_
45	recognizing	_	VERB	_	VerbForm=Ger	_	_	_	_
46	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
47	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
48	element	_	NOUN	_	Number=Sing	_	_	_	_
49	undergoes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
50	differential	_	ADJ	_	Degree=Pos	_	_	_	_
51	modification	_	NOUN	_	Number=Sing	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
54	and	_	CCONJ	_	_	_	_	_	_
55	T	_	NOUN	_	Number=Sing	_	_	_	_
56	cells	_	NOUN	_	Number=Plur	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	thus	_	ADV	_	_	_	_	_	_
59	supporting	_	VERB	_	VerbForm=Ger	_	_	_	_
60	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
61	transfection	_	NOUN	_	Number=Sing	_	_	_	_
62	data	_	NOUN	_	Number=Sing	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	while	_	SCONJ	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	peri-kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
20	esters	_	NOUN	_	Number=Plur	_	_	_	_
21	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	additional	_	ADJ	_	Degree=Pos	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Understanding	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	function	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	peri-kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	ultimately	_	ADV	_	_	_	_	_	_
14	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
15	insight	_	NOUN	_	Number=Sing	_	_	_	_
16	into	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	different	_	ADJ	_	Degree=Pos	_	_	_	_
19	role	_	NOUN	_	Number=Sing	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	play	_	VERB	_	VerbForm=Inf	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	HIV	_	NOUN	_	Number=Sing	_	_	_	_
27	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001590	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Suppressive	_	ADJ	_	Degree=Pos	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	agents	_	NOUN	_	Number=Plur	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	heat	_	NOUN	_	Number=Sing	_	_	_	_
15	shock	_	NOUN	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Studies	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
6	laboratory	_	NOUN	_	Number=Sing	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	earliest	_	ADJ	_	Degree=Sup	_	_	_	_
12	stages	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	autoimmune	_	ADJ	_	Degree=Pos	_	_	_	_
21	reaction	_	NOUN	_	Number=Sing	_	_	_	_
22	against	_	ADP	_	_	_	_	_	_
23	heat	_	NOUN	_	Number=Sing	_	_	_	_
24	shock	_	NOUN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	60	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	Hsp60	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	interactions	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Hsp60	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	arterial	_	ADJ	_	Degree=Pos	_	_	_	_
11	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	EC	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	require	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	Hsp60	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	certain	_	ADJ	_	Degree=Pos	_	_	_	_
23	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
24	molecules	_	NOUN	_	Number=Plur	_	_	_	_
25	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	simultaneously	_	ADV	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	EC	_	PROPN	_	Number=Sing	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	mechanical	_	ADJ	_	Degree=Pos	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	other	_	ADJ	_	Degree=Pos	_	_	_	_
36	types	_	NOUN	_	Number=Plur	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	stress	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	suppression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	immune	_	NOUN	_	Number=Sing	_	_	_	_
14	responses	_	NOUN	_	Number=Plur	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
17	A	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	CyA	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	atherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
23	lesion	_	NOUN	_	Number=Sing	_	_	_	_
24	formation	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	mice	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	lower	_	VERB	_	Degree=Cmp	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	risk	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	myocardial	_	ADJ	_	Degree=Pos	_	_	_	_
13	infarction	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	men	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	conflicting	_	VERB	_	VerbForm=Ger	_	_	_	_
3	observations	_	NOUN	_	Number=Plur	_	_	_	_
4	may	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	due	_	ADP	_	_	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	different	_	ADJ	_	Degree=Pos	_	_	_	_
9	effects	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	agents	_	NOUN	_	Number=Plur	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
15	molecule	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	Hsp	_	ADJ	_	Degree=Pos	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	EC	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	respectively	_	ADV	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	MATERIAL	_	NOUN	_	Number=Sing	_	_	_	_
2	AND	_	CCONJ	_	_	_	_	_	_
3	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	effects	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	CyA	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	indomethacin	_	NOUN	_	Number=Sing	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	T	_	PROPN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
21	using	_	VERB	_	VerbForm=Ger	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
24	assay	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	explore	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
7	molecules	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
10	chemoattractant	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	MCP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	Hsp60	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
25	vein	_	NOUN	_	Number=Sing	_	_	_	_
26	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
33	blot	_	NOUN	_	Number=Sing	_	_	_	_
34	analyses	_	NOUN	_	Number=Plur	_	_	_	_
35	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	status	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factors	_	NOUN	_	Number=Plur	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	heat	_	NOUN	_	Number=Sing	_	_	_	_
20	shock	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	HSF	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
31	mobility	_	NOUN	_	Number=Sing	_	_	_	_
32	shift	_	NOUN	_	Number=Sing	_	_	_	_
33	assays	_	NOUN	_	Number=Plur	_	_	_	_
34	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	With	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	exception	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	indomethacin	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	agents	_	NOUN	_	Number=Plur	_	_	_	_
13	significantly	_	ADV	_	_	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	T	_	NUM	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	influenza	_	NOUN	_	VerbForm=Inf	_	_	_	_
22	virus	_	NOUN	_	Number=Sing	_	_	_	_
23	antigen	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	dose	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
29	manner	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CyA	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	indomethacin	_	PROPN	_	Number=Sing	_	_	_	_
6	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TNF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
22	molecule	_	NOUN	_	Degree=Pos	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	HUVECs	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	whereas	_	SCONJ	_	_	_	_	_	_
28	aspirin	_	PROPN	_	Number=Sing	_	_	_	_
29	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
32	effect	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	modulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	EC	_	PROPN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	agents	_	NOUN	_	Number=Plur	_	_	_	_
3	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	induced	_	VERB	_	Degree=Pos	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Hsp60	_	NOUN	_	Number=Sing	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	hr	_	NOUN	_	Number=Sing	_	_	_	_
10	after	_	ADP	_	_	_	_	_	_
11	application	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	indomethacin	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	not	_	ADV	_	_	_	_	_	_
10	CyA	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	Hsp70	_	ADJ	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	HUVECs	_	PROPN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	correlated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	induction	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	HSF	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSION	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	agents	_	NOUN	_	Number=Plur	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	except	_	ADP	_	_	_	_	_	_
10	indomethacin	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	immune	_	ADJ	_	Degree=Pos	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	as	_	SCONJ	_	_	_	_	_	_
24	expected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	effective	_	ADJ	_	Degree=Pos	_	_	_	_
31	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
34	molecule	_	NOUN	_	Degree=Pos	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	that	_	SCONJ	_	_	_	_	_	_
39	all	_	DET	_	_	_	_	_	_
40	three	_	NUM	_	NumType=Card	_	_	_	_
41	agents	_	NOUN	_	Number=Plur	_	_	_	_
42	can	_	AUX	_	VerbForm=Fin	_	_	_	_
43	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
44	Hsp60	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	basis	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	notion	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	1	_	X	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	part	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	anti-atherogenic	_	ADJ	_	Degree=Pos	_	_	_	_
18	effect	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
21	may	_	AUX	_	VerbForm=Fin	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	due	_	ADP	_	_	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	prevention	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	sensitized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	T	_	PROPN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	stressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	EC	_	PROPN	_	Number=Sing	_	_	_	_
37	;	_	PUNCT	_	_	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	2	_	X	_	_	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
42	part	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
48	effect	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	CyA	_	PROPN	_	Number=Sing	_	_	_	_
51	may	_	AUX	_	VerbForm=Fin	_	_	_	_
52	be	_	AUX	_	VerbForm=Inf	_	_	_	_
53	due	_	ADP	_	_	_	_	_	_
54	to	_	ADP	_	_	_	_	_	_
55	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
56	potential	_	NOUN	_	Number=Sing	_	_	_	_
57	as	_	ADP	_	_	_	_	_	_
58	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
59	inducer	_	NOUN	_	Number=Sing	_	_	_	_
60	of	_	ADP	_	_	_	_	_	_
61	Hsp60	_	PROPN	_	Degree=Pos	_	_	_	_
62	expression	_	NOUN	_	Number=Sing	_	_	_	_
63	and	_	CCONJ	_	_	_	_	_	_
64	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
65	inability	_	NOUN	_	Number=Sing	_	_	_	_
66	to	_	PART	_	_	_	_	_	_
67	down	_	VERB	_	_	_	_	_	_
68	-	_	PUNCT	_	_	_	_	_	_
69	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
70	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
71	molecule	_	NOUN	_	Degree=Pos	_	_	_	_
72	expression	_	NOUN	_	Number=Sing	_	_	_	_
73	on	_	ADP	_	_	_	_	_	_
74	EC	_	NOUN	_	Number=Sing	_	_	_	_
75	;	_	PUNCT	_	_	_	_	_	_
76	and	_	CCONJ	_	_	_	_	_	_
77	(	_	PUNCT	_	_	_	_	_	_
78	3	_	X	_	_	_	_	_	_
79	)	_	PUNCT	_	_	_	_	_	_
80	that	_	DET	_	_	_	_	_	_
81	down-regulation	_	NOUN	_	Number=Sing	_	_	_	_
82	of	_	ADP	_	_	_	_	_	_
83	MCP	_	PROPN	_	Number=Sing	_	_	_	_
84	-	_	PUNCT	_	_	_	_	_	_
85	1	_	NUM	_	NumType=Card	_	_	_	_
86	expression	_	NOUN	_	Number=Sing	_	_	_	_
87	by	_	ADP	_	_	_	_	_	_
88	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
89	may	_	AUX	_	VerbForm=Fin	_	_	_	_
90	result	_	VERB	_	VerbForm=Inf	_	_	_	_
91	in	_	ADP	_	_	_	_	_	_
92	decreased	_	VERB	_	Degree=Pos	_	_	_	_
93	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
94	of	_	ADP	_	_	_	_	_	_
95	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
96	into	_	ADP	_	_	_	_	_	_
97	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
98	arterial	_	NOUN	_	Degree=Pos	_	_	_	_
99	intima	_	NOUN	_	Number=Sing	_	_	_	_
100	beneath	_	ADP	_	_	_	_	_	_
101	stressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
102	EC	_	NOUN	_	Number=Sing	_	_	_	_
103	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001595	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Distinct	_	ADJ	_	Degree=Pos	_	_	_	_
2	roles	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	chaperone	_	NOUN	_	Number=Sing	_	_	_	_
7	hsp90	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
10	dioxin	_	NOUN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	function	_	NOUN	_	Number=Sing	_	_	_	_
13	via	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	basic	_	ADJ	_	Degree=Pos	_	_	_	_
16	helix	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	loop	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	helix	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	PAS	_	NOUN	_	Number=Sing	_	_	_	_
23	domains	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	dioxin	_	NOUN	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	signal	_	NOUN	_	Number=Sing	_	_	_	_
7	transduction	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	dioxin	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	functions	_	NOUN	_	Number=Plur	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	ligand	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	basic	_	ADJ	_	Degree=Pos	_	_	_	_
5	helix	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	loop	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	helix	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	bHLH	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	motif	_	NOUN	_	Number=Sing	_	_	_	_
14	contiguous	_	ADJ	_	Degree=Pos	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	Per-Arnt	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	Sim	_	PROPN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	PAS	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	homology	_	NOUN	_	Number=Sing	_	_	_	_
24	region	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	extracts	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	nonstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	recovered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
13	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
14	form	_	NOUN	_	Number=Sing	_	_	_	_
15	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	90	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kDa	_	NOUN	_	Number=Sing	_	_	_	_
21	heat	_	NOUN	_	Number=Sing	_	_	_	_
22	shock	_	NOUN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	hsp90	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
30	chaperone	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	reconstituted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	ligand	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	DNA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	form	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	SCONJ	_	_	_	_	_	_
18	using	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	dioxin	_	NOUN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	bHLH	_	ADJ	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	PAS	_	NOUN	_	Number=Sing	_	_	_	_
27	partner	_	NOUN	_	Number=Sing	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	Arnt	_	PROPN	_	Number=Sing	_	_	_	_
30	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	vitro	_	NOUN	_	Number=Sing	_	_	_	_
34	translation	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	reticulocyte	_	NOUN	_	Number=Sing	_	_	_	_
37	lysate	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	PAS	_	PROPN	_	Number=Sing	_	_	_	_
5	domain	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
12	dimerization	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	Arnt	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	mutant	_	NOUN	_	Number=Sing	_	_	_	_
7	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	low	_	ADJ	_	Degree=Pos	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	xenobiotic	_	ADJ	_	Degree=Pos	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	element	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	PAS	_	PROPN	_	Number=Sing	_	_	_	_
22	domain	_	NOUN	_	Number=Sing	_	_	_	_
23	may	_	AUX	_	VerbForm=Fin	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	important	_	ADJ	_	Degree=Pos	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	DNA	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	binding	_	VERB	_	Number=Sing	_	_	_	_
30	affinity	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	specificity	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	receptor	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	possible	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	reconstitute	_	VERB	_	VerbForm=Inf	_	_	_	_
7	dioxin	_	NOUN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	function	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	wheat	_	NOUN	_	Number=Sing	_	_	_	_
15	germ	_	NOUN	_	Number=Sing	_	_	_	_
16	lysate	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	line	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	observations	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	reticulocyte	_	NOUN	_	Number=Sing	_	_	_	_
8	lysate	_	NOUN	_	Number=Sing	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	wheat	_	NOUN	_	PronType=Int	_	_	_	_
12	germ	_	NOUN	_	Number=Sing	_	_	_	_
13	lysate	_	NOUN	_	Number=Sing	_	_	_	_
14	promoted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	association	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	de	_	PROPN	_	Number=Sing	_	_	_	_
19	novo	_	PROPN	_	Number=Sing	_	_	_	_
20	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	dioxin	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	hsp90	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADV	_	_	_	_	_	_
2	least	_	ADV	_	Degree=Sup	_	_	_	_
3	two	_	NUM	_	NumType=Card	_	_	_	_
4	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
5	domains	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	interaction	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	hsp90	_	NOUN	_	Number=Sing	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	ligand	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	domain	_	NOUN	_	Number=Sing	_	_	_	_
19	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	within	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	PAS	_	PROPN	_	Number=Sing	_	_	_	_
23	region	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	surprisingly	_	ADV	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	bHLH	_	PROPN	_	Number=Sing	_	_	_	_
30	domain	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	ligand	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	association	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	hsp90	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	bHLH	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	hsp90	_	NOUN	_	Number=Sing	_	_	_	_
15	interaction	_	NOUN	_	Number=Sing	_	_	_	_
16	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	important	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	DNA	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	binding	_	VERB	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	not	_	ADV	_	_	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	dimerization	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	receptor	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
3	roles	_	NOUN	_	Number=Plur	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	hsp90	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	SCONJ	_	_	_	_	_	_
7	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	dioxin	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	function	_	NOUN	_	Number=Sing	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	therefore	_	ADV	_	_	_	_	_	_
13	likely	_	ADJ	_	Degree=Pos	_	_	_	_
14	:	_	PUNCT	_	_	_	_	_	_
15	correct	_	ADJ	_	Degree=Pos	_	_	_	_
16	folding	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	ligand	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	binding	_	VERB	_	Number=Sing	_	_	_	_
22	domain	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	interference	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	Arnt	_	PROPN	_	Number=Sing	_	_	_	_
27	heterodimerization	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	folding	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	DNA	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	binding	_	VERB	_	Number=Sing	_	_	_	_
36	conformation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	bHLH	_	ADJ	_	Number=Sing	_	_	_	_
40	domain	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	dioxin	_	NOUN	_	Number=Sing	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	system	_	NOUN	_	Number=Sing	_	_	_	_
7	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	complex	_	NOUN	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	interesting	_	ADJ	_	Degree=Pos	_	_	_	_
12	model	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	hsp90	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001600	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	New	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
3	drug	_	NOUN	_	Number=Sing	_	_	_	_
4	PNU156804	_	NOUN	_	Number=Sing	_	_	_	_
5	blocks	_	NOUN	_	Number=Plur	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	drug	_	NOUN	_	Number=Sing	_	_	_	_
8	undecylprodigiosin	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	UP	_	NOUN	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	blocks	_	NOUN	_	Number=Plur	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	vitro	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	now	_	ADV	_	_	_	_	_	_
4	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	action	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	new	_	ADJ	_	Degree=Pos	_	_	_	_
12	analogue	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	UP	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	PNU156804	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	more	_	ADV	_	_	_	_	_	_
22	favorable	_	ADJ	_	Degree=Pos	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	profile	_	NOUN	_	Number=Sing	_	_	_	_
25	than	_	ADP	_	_	_	_	_	_
26	UP	_	ADP	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	mice	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	biological	_	ADJ	_	Degree=Pos	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	PNU156804	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	vitro	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	indistinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	UP	_	NOUN	_	Number=Sing	_	_	_	_
16	:	_	PUNCT	_	_	_	_	_	_
17	PNU156804	_	NUM	_	NumType=Card	_	_	_	_
18	blocks	_	NOUN	_	Number=Plur	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	mid	_	X	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	late	_	ADJ	_	Degree=Pos	_	_	_	_
27	G1	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	as	_	SCONJ	_	_	_	_	_	_
30	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	cycle	_	NOUN	_	Number=Sing	_	_	_	_
34	analysis	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	cyclins	_	NOUN	_	Number=Plur	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
44	kinases	_	NOUN	_	Number=Plur	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
47	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	PNU156804	_	NOUN	_	Number=Sing	_	_	_	_
8	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	block	_	VERB	_	VerbForm=Inf	_	_	_	_
11	significantly	_	ADV	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	either	_	CCONJ	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2R	_	NOUN	_	Number=Sing	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	gamma	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	chains	_	NOUN	_	Number=Plur	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
36	T	_	NOUN	_	Number=Sing	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	several	_	ADJ	_	Degree=Pos	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	pathways	_	NOUN	_	Number=Plur	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	PNU156804	_	NOUN	_	Number=Sing	_	_	_	_
5	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
8	c-myc	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	bcl	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	hand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	PNU156804	_	PROPN	_	Number=Sing	_	_	_	_
7	efficiently	_	ADV	_	_	_	_	_	_
8	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	PNU156804	_	NOUN	_	Number=Sing	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	due	_	ADP	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	degradation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	kappa	_	VERB	_	Number=Sing	_	_	_	_
20	B	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	kappa	_	VERB	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	beta	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	PNU156804	_	NOUN	_	Number=Sing	_	_	_	_
2	action	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	some	_	DET	_	_	_	_	_	_
7	signaling	_	VERB	_	Number=Sing	_	_	_	_
8	pathways	_	NOUN	_	Number=Plur	_	_	_	_
9	;	_	PUNCT	_	_	_	_	_	_
10	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
11	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	PMA	_	PROPN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	blocks	_	NOUN	_	Number=Plur	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	CD40	_	PROPN	_	Number=Sing	_	_	_	_
30	cross	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	prodigiosin	_	NOUN	_	Number=Sing	_	_	_	_
6	family	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	immunosuppressants	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	new	_	ADJ	_	Degree=Pos	_	_	_	_
12	family	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	molecules	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	novel	_	NOUN	_	Number=Sing	_	_	_	_
19	target	_	NOUN	_	Number=Sing	_	_	_	_
20	specificity	_	NOUN	_	Number=Sing	_	_	_	_
21	clearly	_	ADV	_	_	_	_	_	_
22	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	other	_	ADJ	_	Degree=Pos	_	_	_	_
27	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
28	drugs	_	NOUN	_	Number=Plur	_	_	_	_
29	such	_	ADJ	_	Degree=Pos	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
32	A	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	FK506	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001605	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interaction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	RFX1	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	MIBP1	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	gamma	_	NOUN	_	Number=Sing	_	_	_	_
11	motif	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	negative	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	hepatitis	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	virus	_	NOUN	_	Number=Sing	_	_	_	_
22	core	_	NOUN	_	Number=Sing	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	negative	_	ADJ	_	Degree=Pos	_	_	_	_
3	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	element	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	NRE	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	hepatitis	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	virus	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	HBV	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	core	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	three	_	NUM	_	NumType=Card	_	_	_	_
20	subregions	_	NOUN	_	Number=Plur	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	act	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	synergistically	_	ADV	_	_	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
26	core	_	NOUN	_	Number=Sing	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	subregions	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	NRE	_	PROPN	_	Number=Sing	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	active	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
14	cervical	_	ADJ	_	Degree=Pos	_	_	_	_
15	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	Huh7	_	ADJ	_	Degree=Pos	_	_	_	_
19	hepatoma	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	bound	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	present	_	ADJ	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	both	_	DET	_	_	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	types	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	RFX1	_	PROPN	_	Number=Sing	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	NRE	_	PROPN	_	Number=Sing	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	core	_	NOUN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	through	_	ADP	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	which	_	PRON	_	PronType=Rel	_	_	_	_
3	abrogated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	suppressive	_	ADJ	_	Degree=Pos	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NRE	_	PROPN	_	Number=Sing	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	RFX1	_	NOUN	_	Number=Sing	_	_	_	_
14	from	_	SCONJ	_	_	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	NRE	_	PROPN	_	Number=Sing	_	_	_	_
18	gamma	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	RFX1	_	NOUN	_	Number=Sing	_	_	_	_
5	can	_	AUX	_	VerbForm=Fin	_	_	_	_
6	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
7	simultaneously	_	ADV	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	most	_	ADV	_	_	_	_	_	_
10	likely	_	ADV	_	Degree=Pos	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	MIBP1	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	NRE	_	PROPN	_	Number=Sing	_	_	_	_
22	gamma	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	absence	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	cloned	_	ADJ	_	Degree=Pos	_	_	_	_
7	MIBP1	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	further	_	ADJ	_	Degree=Pos	_	_	_	_
11	studies	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	hypothesize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	RFX1	_	PROPN	_	Number=Sing	_	_	_	_
17	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	MIBP1	_	PROPN	_	Number=Sing	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	negatively	_	ADV	_	_	_	_	_	_
22	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	core	_	NOUN	_	Number=Sing	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	through	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	NRE	_	PROPN	_	Number=Sing	_	_	_	_
30	gamma	_	NOUN	_	Number=Sing	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	RFX1	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	core	_	NOUN	_	Number=Sing	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	raises	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	possibility	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	RFX1	_	PROPN	_	Number=Sing	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	play	_	VERB	_	VerbForm=Inf	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	dual	_	ADJ	_	Degree=Pos	_	_	_	_
19	role	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	SCONJ	_	_	_	_	_	_
21	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	HBV	_	PROPN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001611	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Danazol	_	PROPN	_	Number=Sing	_	_	_	_
2	decreases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	estrogen	_	NOUN	_	Degree=Pos	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	1	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	Administration	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	danazol	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	over	_	ADP	_	_	_	_	_	_
8	one	_	NUM	_	NumType=Card	_	_	_	_
9	month	_	NOUN	_	Number=Sing	_	_	_	_
10	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	estrogen	_	NOUN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	ER	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	approximately	_	ADV	_	_	_	_	_	_
24	50	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	20	_	NUM	_	NumType=Card	_	_	_	_
27	%	_	SYM	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	respectively	_	ADV	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	2	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	Danazol	_	PROPN	_	Number=Sing	_	_	_	_
4	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	degradation	_	NOUN	_	Number=Sing	_	_	_	_
9	rate	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	ER	_	NOUN	_	Number=Sing	_	_	_	_
12	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	3	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	Danazol	_	PROPN	_	Number=Sing	_	_	_	_
4	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	rate	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	ER	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	approximately	_	ADV	_	_	_	_	_	_
13	50	_	NUM	_	NumType=Card	_	_	_	_
14	%	_	SYM	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	run	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	assay	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	4	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	Danazol	_	PROPN	_	Number=Sing	_	_	_	_
4	may	_	AUX	_	VerbForm=Fin	_	_	_	_
5	release	_	VERB	_	VerbForm=Inf	_	_	_	_
6	estrogen	_	ADJ	_	Degree=Pos	_	_	_	_
7	predominance	_	NOUN	_	Number=Sing	_	_	_	_
8	via	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	reduction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	ER	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	reduction	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	ER	_	NOUN	_	Number=Sing	_	_	_	_
24	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	ER	_	NOUN	_	Number=Sing	_	_	_	_
27	expressions	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001613	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cross	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	linking	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	CD30	_	PROPN	_	Number=Sing	_	_	_	_
6	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	chronically	_	ADV	_	_	_	_	_	_
11	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	CD30	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	member	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	tumor	_	NOUN	_	Number=Sing	_	_	_	_
8	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	family	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	constitutively	_	ADV	_	_	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	surface	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	line	_	NOUN	_	Number=Sing	_	_	_	_
28	ACH	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	chronically	_	ADV	_	_	_	_	_	_
35	infected	_	VERB	_	Degree=Pos	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	human	_	ADJ	_	Degree=Pos	_	_	_	_
38	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
39	virus	_	NOUN	_	Number=Sing	_	_	_	_
40	type	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	HIV	_	NOUN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	cross	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
7	CD30	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	anti-CD30-specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
12	antibody	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	mimics	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	biological	_	ADJ	_	Degree=Pos	_	_	_	_
19	activities	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	CD30	_	PROPN	_	Number=Sing	_	_	_	_
23	ligand	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	CD30L	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	results	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	HIV	_	NOUN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	CD30	_	PROPN	_	Number=Sing	_	_	_	_
2	cross	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	linking	_	NOUN	_	Number=Sing	_	_	_	_
5	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
8	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	ACH	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
25	TNF	_	PROPN	_	Number=Sing	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	beta	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cross	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	linking	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CD30	_	NOUN	_	Number=Sing	_	_	_	_
8	leads	_	NOUN	_	Number=Plur	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CD30	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	CD30L	_	PROPN	_	Number=Sing	_	_	_	_
6	interactions	_	NOUN	_	Number=Plur	_	_	_	_
7	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	pathway	_	NOUN	_	Number=Sing	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	independent	_	ADJ	_	Degree=Pos	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	TNF	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	may	_	AUX	_	VerbForm=Fin	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	latently	_	ADV	_	_	_	_	_	_
14	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	CD4	_	PROPN	_	Number=Sing	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_

1	T	_	X	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	especially	_	ADV	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
7	organs	_	NOUN	_	Number=Plur	_	_	_	_
8	where	_	ADV	_	PronType=Rel	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	contact	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	conducive	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	ligand	_	NOUN	_	Number=Sing	_	_	_	_
19	interactions	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001619	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	intricate	_	ADJ	_	Degree=Pos	_	_	_	_
3	arrangement	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Ets	_	NOUN	_	Number=Sing	_	_	_	_
10	family	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	alpha	_	PROPN	_	Number=Sing	_	_	_	_
19	4	_	NUM	_	NumType=Card	_	_	_	_
20	integrin	_	NOUN	_	Degree=Pos	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	alpha	_	NOUN	_	Number=Sing	_	_	_	_
2	4	_	NUM	_	NumType=Card	_	_	_	_
3	integrins	_	NOUN	_	Number=Plur	_	_	_	_
4	mediate	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
12	matrix	_	NOUN	_	Number=Sing	_	_	_	_
13	interactions	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	critical	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	maturation	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	function	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	immune	_	NOUN	_	Number=Sing	_	_	_	_
24	system	_	NOUN	_	Number=Sing	_	_	_	_
25	as	_	ADV	_	_	_	_	_	_
26	well	_	ADV	_	Degree=Pos	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	skeletal	_	ADJ	_	Degree=Pos	_	_	_	_
31	muscle	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	examine	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
6	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	pattern	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	constructs	_	NOUN	_	Number=Plur	_	_	_	_
5	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	5	_	NUM	_	NumType=Card	_	_	_	_
7	'	_	PUNCT	_	_	_	_	_	_
8	deletion	_	NOUN	_	Number=Sing	_	_	_	_
9	mutants	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	transfection	_	NOUN	_	Number=Sing	_	_	_	_
20	assays	_	VERB	_	Number=Plur	_	_	_	_
21	into	_	ADP	_	_	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	lines	_	NOUN	_	Number=Plur	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	4	_	NUM	_	NumType=Card	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	lines	_	NOUN	_	Number=Plur	_	_	_	_
31	that	_	PRON	_	PronType=Rel	_	_	_	_
32	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	not	_	PART	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	position	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	42	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	-	_	SYM	_	_	_	_	_	_
9	76	_	NUM	_	NumType=Card	_	_	_	_
10	base	_	NOUN	_	Number=Sing	_	_	_	_
11	pairs	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	bp	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	alpha	_	PROPN	_	Number=Sing	_	_	_	_
25	4	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
29	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	no	_	DET	_	_	_	_	_	_
31	activity	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	which	_	PRON	_	PronType=Rel	_	_	_	_
37	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	not	_	PART	_	_	_	_	_	_
39	express	_	VERB	_	VerbForm=Inf	_	_	_	_
40	alpha	_	PROPN	_	Number=Sing	_	_	_	_

1	4	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_

1	Three	_	NUM	_	NumType=Card	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	sites	_	NOUN	_	Number=Plur	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	Ets	_	NOUN	_	Number=Sing	_	_	_	_
7	family	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	:	_	PUNCT	_	_	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
19	sites	_	NOUN	_	Number=Plur	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	positions	_	NOUN	_	Number=Plur	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	50	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	54	_	NUM	_	NumType=Card	_	_	_	_
27	bp	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	more	_	ADV	_	_	_	_	_	_
31	5	_	NUM	_	NumType=Card	_	_	_	_
32	'	_	NOUN	_	_	_	_	_	_
33	site	_	NOUN	_	Number=Sing	_	_	_	_
34	at	_	ADP	_	_	_	_	_	_
35	position	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	67	_	NUM	_	NumType=Card	_	_	_	_
38	bp	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	series	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	constructs	_	NOUN	_	Number=Plur	_	_	_	_
6	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	deletions	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	mutations	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	3'-	_	ADJ	_	_	_	_	_	_
19	most	_	ADJ	_	Degree=Sup	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	alone	_	ADV	_	_	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
24	for	_	SCONJ	_	_	_	_	_	_
25	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
26	GA	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	binding	_	VERB	_	Number=Sing	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	GABP	_	NOUN	_	Number=Sing	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	/	_	PUNCT	_	_	_	_	_	_
36	GABP	_	NOUN	_	Number=Sing	_	_	_	_
37	beta	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	low	_	ADJ	_	Degree=Pos	_	_	_	_
42	level	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	all	_	DET	_	_	_	_	_	_
3	three	_	NUM	_	NumType=Card	_	_	_	_
4	sites	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	present	_	ADJ	_	Degree=Pos	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
10	complex	_	NOUN	_	Number=Sing	_	_	_	_
11	"	_	PUNCT	_	_	_	_	_	_
12	a	_	NOUN	_	Number=Sing	_	_	_	_
13	"	_	PUNCT	_	_	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
21	member	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	Ets	_	NOUN	_	Number=Sing	_	_	_	_
25	family	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Formation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	complex	_	NOUN	_	Number=Sing	_	_	_	_
4	a	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	correlated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	high	_	ADJ	_	Degree=Pos	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	5'-	_	NUM	_	_	_	_	_	_
5	most	_	ADJ	_	Degree=Sup	_	_	_	_
6	Ets	_	NOUN	_	Number=Plur	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	no	_	DET	_	_	_	_	_	_
10	effect	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	SCONJ	_	_	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	GABP	_	NOUN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	GABP	_	NOUN	_	Number=Sing	_	_	_	_
18	beta	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	eliminated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Concomitant	_	ADJ	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	loss	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	new	_	ADJ	_	Degree=Pos	_	_	_	_
10	Ets-1	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	complex	_	NOUN	_	Number=Sing	_	_	_	_
14	"	_	PUNCT	_	_	_	_	_	_
15	c	_	NOUN	_	Number=Sing	_	_	_	_
16	"	_	PUNCT	_	_	_	_	_	_
17	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Complex	_	ADJ	_	Number=Sing	_	_	_	_
2	c	_	NOUN	_	Number=Sing	_	_	_	_
3	substituted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	efficiently	_	ADV	_	_	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	complex	_	NOUN	_	Number=Sing	_	_	_	_
7	a	_	NOUN	_	Definite=Ind|PronType=Art	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	although	_	SCONJ	_	_	_	_	_	_
5	neither	_	DET	_	_	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	5'-	_	NUM	_	Number=Plur	_	_	_	_
10	most	_	ADJ	_	Degree=Sup	_	_	_	_
11	Ets	_	NOUN	_	Number=Plur	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	alone	_	ADV	_	_	_	_	_	_
14	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
19	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	act	_	VERB	_	VerbForm=Inf	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	modulators	_	NOUN	_	Number=Plur	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	pattern	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	Ets	_	NOUN	_	Number=Sing	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	that	_	PRON	_	PronType=Rel	_	_	_	_
32	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	alpha	_	NOUN	_	Number=Sing	_	_	_	_
35	4	_	NUM	_	NumType=Card	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	promoter	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	arrangement	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Ets	_	NOUN	_	Number=Sing	_	_	_	_
5	sites	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	tissue	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	Ets	_	NOUN	_	Number=Sing	_	_	_	_
19	members	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	likely	_	ADV	_	_	_	_	_	_
22	play	_	VERB	_	VerbForm=Inf	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	key	_	ADJ	_	Degree=Pos	_	_	_	_
25	role	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	SCONJ	_	_	_	_	_	_
27	defining	_	VERB	_	VerbForm=Ger	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	pattern	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	4	_	NUM	_	NumType=Card	_	_	_	_
33	integrin	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001620	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Kappa	_	PROPN	_	Number=Sing	_	_	_	_
2	B-specific	_	ADJ	_	Number=Sing	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	differentially	_	ADV	_	_	_	_	_	_
8	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
11	mutations	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	biological	_	ADJ	_	Degree=Pos	_	_	_	_
14	oxidation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Kappa	_	PROPN	_	Number=Sing	_	_	_	_
2	B	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
20	two	_	NUM	_	NumType=Card	_	_	_	_
21	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
22	nucleoprotein	_	NOUN	_	Number=Sing	_	_	_	_
23	complexes	_	NOUN	_	Number=Plur	_	_	_	_
24	when	_	ADV	_	PronType=Int	_	_	_	_
25	incubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	element	_	NOUN	_	Number=Sing	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	receptor	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	alpha	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	2R	_	NOUN	_	Number=Sing	_	_	_	_
43	alpha	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	gene	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	DNA	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	complexes	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	at	_	ADV	_	_	_	_	_	_
11	least	_	ADV	_	Degree=Sup	_	_	_	_
12	four	_	NUM	_	NumType=Card	_	_	_	_
13	host	_	NOUN	_	Number=Sing	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	p50	_	NUM	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	p55	_	NUM	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	p75	_	NUM	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	p85	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	each	_	DET	_	_	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	which	_	PRON	_	PronType=Int	_	_	_	_
28	shares	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	structural	_	ADJ	_	Degree=Pos	_	_	_	_
30	similarity	_	NOUN	_	Number=Sing	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	v-rel	_	NOUN	_	Degree=Pos	_	_	_	_
34	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
35	product	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	distinctly	_	ADV	_	_	_	_	_	_
10	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
11	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
12	following	_	VERB	_	VerbForm=Ger	_	_	_	_
13	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
14	ester	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	p55	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	p75	_	NOUN	_	Number=Sing	_	_	_	_
23	early	_	ADV	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	p50/p85	_	NUM	_	NumType=Card	_	_	_	_
26	late	_	ADV	_	Degree=Pos	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	crosslinking	_	NOUN	_	Number=Sing	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	more	_	ADV	_	_	_	_	_	_
11	rapidly	_	ADV	_	_	_	_	_	_
12	migrating	_	VERB	_	VerbForm=Ger	_	_	_	_

1	B2	_	PROPN	_	Number=Sing	_	_	_	_
2	complex	_	NOUN	_	Number=Sing	_	_	_	_
3	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	p50	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	p55	_	NUM	_	Number=Sing	_	_	_	_
8	while	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	more	_	ADV	_	_	_	_	_	_
11	slowly	_	ADV	_	_	_	_	_	_
12	migrating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	B1	_	PROPN	_	Number=Sing	_	_	_	_
14	complex	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	p50	_	NUM	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	p55	_	NOUN	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	p75	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	p85	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Site	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	wild	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2R	_	PROPN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	kappa	_	PROPN	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	GGGGAATCTCCC	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	p50	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	p55	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	B2	_	NOUN	_	Number=Sing	_	_	_	_
31	complex	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	particularly	_	ADV	_	_	_	_	_	_
35	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	alteration	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	5	_	NUM	_	NumType=Card	_	_	_	_
41	'	_	PUNCT	_	_	_	_	_	_
42	triplet	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	deoxyguanosine	_	NOUN	_	Degree=Pos	_	_	_	_
45	residues	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	formation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	B1	_	PROPN	_	Number=Sing	_	_	_	_
8	complex	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	reflecting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	p75	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	p85	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	critically	_	ADV	_	_	_	_	_	_
19	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	upon	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	more	_	ADV	_	_	_	_	_	_
23	3	_	NUM	_	NumType=Card	_	_	_	_
24	'	_	PUNCT	_	_	_	_	_	_
25	sequences	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
29	element	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	all	_	DET	_	_	_	_	_	_
5	four	_	NUM	_	NumType=Card	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	Rel	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	related	_	ADJ	_	Degree=Pos	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	selective	_	ADJ	_	Degree=Pos	_	_	_	_
16	chemical	_	ADJ	_	Degree=Pos	_	_	_	_
17	modification	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	lysine	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	arginine	_	VERB	_	Number=Sing	_	_	_	_
22	residues	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	both	_	DET	_	_	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	basic	_	ADJ	_	Degree=Pos	_	_	_	_
30	amino	_	NOUN	_	Number=Sing	_	_	_	_
31	acids	_	NOUN	_	Number=Plur	_	_	_	_
32	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	for	_	SCONJ	_	_	_	_	_	_
35	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	kappa	_	NOUN	_	Number=Sing	_	_	_	_
39	B	_	NOUN	_	Number=Sing	_	_	_	_
40	element	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Similarly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	covalent	_	ADJ	_	Degree=Pos	_	_	_	_
4	modification	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	free	_	ADJ	_	Degree=Pos	_	_	_	_
7	sulfhydryl	_	NOUN	_	Number=Sing	_	_	_	_
8	groups	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	diamide	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	reversible	_	ADJ	_	Degree=Pos	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	N	_	ADJ	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	ethylmaleimide	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	irreversible	_	ADJ	_	Degree=Pos	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	results	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	complete	_	ADJ	_	Degree=Pos	_	_	_	_
25	loss	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	DNA	_	NOUN	_	Number=Sing	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	mild	_	ADJ	_	Degree=Pos	_	_	_	_
5	oxidation	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	glucose	_	ADJ	_	Number=Sing	_	_	_	_
8	oxidase	_	NOUN	_	Number=Sing	_	_	_	_
9	selectively	_	ADV	_	_	_	_	_	_
10	inhibits	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	p75	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	p85	_	NUM	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	while	_	SCONJ	_	_	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
18	p50	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	p55	_	NOUN	_	Number=Sing	_	_	_	_
21	interactions	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
7	thiols	_	NOUN	_	Number=Plur	_	_	_	_
8	play	_	VERB	_	VerbForm=Inf	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	DNA	_	PROPN	_	Number=Sing	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	family	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	Rel	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	related	_	ADJ	_	Degree=Pos	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factors	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001626	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Involvement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
7	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
8	molecule	_	NOUN	_	Number=Sing	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
4	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
5	molecules	_	NOUN	_	Number=Plur	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TNF	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	can	_	AUX	_	VerbForm=Fin	_	_	_	_
18	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
19	independently	_	ADV	_	_	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	kinase	_	NOUN	_	Number=Sing	_	_	_	_
23	C	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	PTK	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	recently	_	ADV	_	_	_	_	_	_
36	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
37	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
43	cell	_	NOUN	_	Number=Sing	_	_	_	_
44	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
45	molecule	_	NOUN	_	Number=Sing	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	1	_	NUM	_	NumType=Card	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	by	_	ADP	_	_	_	_	_	_
53	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	4	_	NUM	_	NumType=Card	_	_	_	_
56	(	_	PUNCT	_	_	_	_	_	_
57	IL	_	PROPN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	4	_	NUM	_	NumType=Card	_	_	_	_
60	)	_	PUNCT	_	_	_	_	_	_
61	on	_	ADP	_	_	_	_	_	_
62	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
63	cells	_	NOUN	_	Number=Plur	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	PTK	_	PROPN	_	Number=Sing	_	_	_	_
6	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
7	herbimycin	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	A	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	genistein	_	PROPN	_	Number=Sing	_	_	_	_
11	suppress	_	NOUN	_	Number=Sing	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	endothelial	_	NOUN	_	Number=Sing	_	_	_	_
15	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	E-selectin	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	as	_	ADV	_	_	_	_	_	_
22	well	_	ADV	_	Degree=Pos	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
25	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	TNF	_	PROPN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	following	_	VERB	_	VerbForm=Ger	_	_	_	_
9	PTK	_	PROPN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	involved	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	have	_	VERB	_	VerbForm=Inf	_	_	_	_
4	implications	_	NOUN	_	Number=Plur	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	pathophysiological	_	ADJ	_	Degree=Pos	_	_	_	_
7	conditions	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	involve	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	molecules	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	e.g.	_	X	_	_	_	_	_	_
17	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001627	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nonpituitary	_	ADJ	_	Degree=Pos	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	prolactin	_	NOUN	_	Number=Sing	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	independent	_	ADJ	_	Degree=Pos	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Pit	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	differentially	_	ADV	_	_	_	_	_	_
14	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	endometrial	_	ADJ	_	Degree=Pos	_	_	_	_
20	stroma	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	PRL	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	hPRL	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	extrapituitary	_	ADJ	_	Degree=Pos	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	such	_	ADJ	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	uterus	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	decidualized	_	VERB	_	Degree=Pos	_	_	_	_
19	endometrial	_	ADJ	_	Degree=Pos	_	_	_	_
20	stroma	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	myometrium	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
29	lineage	_	NOUN	_	Number=Sing	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	directed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	which	_	PRON	_	PronType=Rel	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	approximately	_	ADV	_	_	_	_	_	_
40	6	_	NUM	_	NumType=Card	_	_	_	_
41	kilobases	_	NOUN	_	Number=Plur	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	kb	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	upstream	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	specific	_	ADJ	_	Degree=Pos	_	_	_	_
51	start	_	NOUN	_	Number=Sing	_	_	_	_
52	site	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	delineate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	tissue	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
10	governing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	control	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	nonpituitary	_	ADJ	_	Degree=Pos	_	_	_	_
15	PRL	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	sequenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	kb	_	NOUN	_	Number=Sing	_	_	_	_
26	5	_	NUM	_	NumType=Card	_	_	_	_
27	'-	_	PUNCT	_	_	_	_	_	_
28	flanking	_	VERB	_	VerbForm=Ger	_	_	_	_
29	DNA	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
33	decidual	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	dPRL	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	promoter	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	homology	_	NOUN	_	Number=Sing	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	motifs	_	NOUN	_	Number=Plur	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	Pit	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	seven	_	NUM	_	NumType=Card	_	_	_	_
16	half	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	PR	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	focused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Pit	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	PR	_	NOUN	_	Number=Sing	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	potential	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	regulators	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	since	_	SCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	POU	_	PROPN	_	Number=Sing	_	_	_	_
23	domain	_	NOUN	_	Number=Sing	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	Pit	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	essential	_	ADJ	_	Degree=Pos	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	control	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
35	PRL	_	NOUN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
40	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	decidual	_	ADJ	_	Degree=Pos	_	_	_	_
42	transformation	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	endometrial	_	ADJ	_	Degree=Pos	_	_	_	_
46	stroma	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
49	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
50	process	_	NOUN	_	Number=Sing	_	_	_	_
51	during	_	ADP	_	_	_	_	_	_
52	which	_	PRON	_	PronType=Rel	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	decidual	_	ADJ	_	Degree=Pos	_	_	_	_
55	PRL	_	NOUN	_	Number=Sing	_	_	_	_
56	gene	_	NOUN	_	Number=Sing	_	_	_	_
57	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
58	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	variety	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	types	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	including	_	VERB	_	VerbForm=Ger	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	endometrial	_	ADJ	_	Degree=Pos	_	_	_	_
14	stroma	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	that	_	PRON	_	_	_	_	_	_
17	Pit	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	involved	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	regulation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	dPRL	_	NOUN	_	Number=Sing	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	reporter	_	NOUN	_	Number=Sing	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	constructs	_	NOUN	_	Number=Plur	_	_	_	_
33	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
34	3	_	NUM	_	NumType=Card	_	_	_	_
35	kb	_	NOUN	_	Number=Sing	_	_	_	_
36	5	_	NUM	_	NumType=Card	_	_	_	_
37	'-	_	PUNCT	_	_	_	_	_	_
38	flanking	_	NOUN	_	VerbForm=Ger	_	_	_	_
39	DNA	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	PR	_	NOUN	_	Number=Sing	_	_	_	_
8	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	confer	_	VERB	_	VerbForm=Inf	_	_	_	_
11	direct	_	ADJ	_	Degree=Pos	_	_	_	_
12	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
13	control	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	dPRL	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	dPRL	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	PRL	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	secreting	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	nonsecreting	_	ADJ	_	Degree=Pos	_	_	_	_
17	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
21	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	kb	_	NOUN	_	Number=Sing	_	_	_	_
26	5	_	NUM	_	NumType=Card	_	_	_	_
27	'-	_	PUNCT	_	_	_	_	_	_
28	flanking	_	VERB	_	Number=Sing	_	_	_	_
29	region	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	dPRL	_	NOUN	_	Number=Sing	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	not	_	PART	_	_	_	_	_	_
36	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
37	elements	_	NOUN	_	Number=Plur	_	_	_	_
38	restricting	_	VERB	_	VerbForm=Ger	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	only	_	ADV	_	_	_	_	_	_
42	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
43	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
44	that	_	PRON	_	PronType=Rel	_	_	_	_
45	produce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
46	PRL	_	NOUN	_	Number=Sing	_	_	_	_
47	but	_	CCONJ	_	_	_	_	_	_
48	allowed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	expression	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	fusion	_	NOUN	_	Number=Sing	_	_	_	_
52	reporter	_	NOUN	_	Number=Sing	_	_	_	_
53	genes	_	NOUN	_	Number=Plur	_	_	_	_
54	irrespective	_	ADV	_	_	_	_	_	_
55	of	_	ADP	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	status	_	NOUN	_	Number=Sing	_	_	_	_
58	of	_	ADP	_	_	_	_	_	_
59	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
60	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
61	PRL	_	NOUN	_	Number=Sing	_	_	_	_
62	gene	_	NOUN	_	Number=Sing	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	sharp	_	ADJ	_	Degree=Pos	_	_	_	_
5	contrast	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	endometrial	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	where	_	ADV	_	PronType=Rel	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	kb	_	NOUN	_	Number=Sing	_	_	_	_
12	5	_	NUM	_	NumType=Card	_	_	_	_
13	'-	_	PUNCT	_	_	_	_	_	_
14	flanking	_	VERB	_	VerbForm=Ger	_	_	_	_
15	DNA	_	PROPN	_	Number=Sing	_	_	_	_
16	conferred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	strong	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	dPRL	_	NOUN	_	Number=Sing	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	decidualized	_	VERB	_	Degree=Pos	_	_	_	_
26	endometrial	_	ADJ	_	Degree=Pos	_	_	_	_
27	stromal	_	ADJ	_	Degree=Pos	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	actively	_	ADV	_	_	_	_	_	_
30	secreting	_	VERB	_	VerbForm=Ger	_	_	_	_
31	PRL	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	but	_	CCONJ	_	_	_	_	_	_
34	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	not	_	PART	_	_	_	_	_	_
36	allow	_	VERB	_	VerbForm=Inf	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	undifferentiated	_	ADJ	_	Degree=Pos	_	_	_	_
40	non-PRL	_	NOUN	_	Degree=Pos	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	secreting	_	VERB	_	VerbForm=Ger	_	_	_	_
43	endometrial	_	ADJ	_	Degree=Pos	_	_	_	_
44	stromal	_	ADJ	_	Degree=Pos	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	dPRL	_	NOUN	_	Number=Sing	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	construct	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	undifferentiated	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	could	_	AUX	_	VerbForm=Fin	_	_	_	_
12	however	_	ADV	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	addition	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	absence	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	progesterone	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	signal	_	NOUN	_	Number=Sing	_	_	_	_
31	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	through	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
35	signaling	_	NOUN	_	Number=Sing	_	_	_	_
36	pathway	_	NOUN	_	Number=Sing	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	primary	_	ADJ	_	Degree=Pos	_	_	_	_
40	inducer	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	decidual	_	ADJ	_	Degree=Pos	_	_	_	_
43	PRL	_	NOUN	_	Number=Sing	_	_	_	_
44	gene	_	NOUN	_	Number=Sing	_	_	_	_
45	expression	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001631	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	reactivation	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	SCONJ	_	_	_	_	_	_
6	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
7	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
8	blood	_	NOUN	_	Number=Sing	_	_	_	_
9	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	adults	_	NOUN	_	Number=Plur	_	_	_	_
14	upon	_	ADP	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	vitro	_	PROPN	_	Number=Sing	_	_	_	_
17	CD4	_	PROPN	_	Number=Sing	_	_	_	_
18	cross	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	ligands	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	CDR2	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	loop	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
30	domain	_	NOUN	_	Number=Sing	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	infects	_	NOUN	_	Number=Plur	_	_	_	_
5	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
6	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
7	blood	_	NOUN	_	Number=Sing	_	_	_	_
8	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	PBMCs	_	NOUN	_	Number=Plur	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
16	state	_	NOUN	_	Number=Sing	_	_	_	_
17	until	_	ADP	_	_	_	_	_	_
18	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	cross	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	linking	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	surface	_	NOUN	_	Number=Sing	_	_	_	_
12	CD4	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	gp120	_	NUM	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	anti-gp120	_	NUM	_	NumType=Card	_	_	_	_
17	immune	_	NOUN	_	Number=Sing	_	_	_	_
18	complexes	_	NOUN	_	Number=Plur	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	heat	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	inactivated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	HIV	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	iHIV	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	trigger	_	VERB	_	VerbForm=Inf	_	_	_	_
35	activation	_	NOUN	_	Number=Sing	_	_	_	_
36	signals	_	NOUN	_	Number=Plur	_	_	_	_
37	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	virus	_	NOUN	_	Number=Sing	_	_	_	_
40	reactivation	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	9	_	NUM	_	NumType=Card	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	translocation	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	iHIV	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	strictly	_	ADV	_	_	_	_	_	_
24	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	viral	_	ADJ	_	Degree=Pos	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
34	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	further	_	ADV	_	_	_	_	_	_
5	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	physiologic	_	ADJ	_	Degree=Pos	_	_	_	_
8	relevance	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	observations	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	submitted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	vitro	_	PROPN	_	Number=Sing	_	_	_	_
7	CD4	_	PROPN	_	Number=Sing	_	_	_	_
8	cross	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	iHIV	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	PBMCs	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	HIV	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	patients	_	NOUN	_	Number=Plur	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
28	virus	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	viral	_	ADJ	_	Degree=Pos	_	_	_	_
3	reactivation	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	translocation	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	patients	_	NOUN	_	Number=Sing	_	_	_	_
15	'	_	PART	_	_	_	_	_	_
16	PBMCs	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	reactivation	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	SCONJ	_	_	_	_	_	_
6	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
7	PBMCs	_	PROPN	_	Number=Plur	_	_	_	_
8	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vitro	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	specifically	_	ADV	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	ligands	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	CDR2	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	loop	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	domain	_	NOUN	_	Number=Sing	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	D1	_	NOUN	_	NumType=Card	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	CD4	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	virus	_	NOUN	_	Number=Sing	_	_	_	_
38	envelope	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	anti-CD4	_	ADJ	_	Number=Sing	_	_	_	_
41	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
42	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	reactivation	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	following	_	VERB	_	VerbForm=Ger	_	_	_	_
10	CD4	_	PROPN	_	Number=Sing	_	_	_	_
11	oligomerization	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	other	_	ADJ	_	Degree=Pos	_	_	_	_
17	epitopes	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	D1	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	including	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	D1/CDR3	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	loop	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
4	CD4	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	sCD4	_	X	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	prevented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	virus	_	NOUN	_	Number=Sing	_	_	_	_
10	reactivation	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	D1/CDR2	_	NUM	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	loop	_	NOUN	_	Number=Sing	_	_	_	_
15	ligands	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	signaling	_	NOUN	_	Number=Sing	_	_	_	_
7	events	_	NOUN	_	Number=Plur	_	_	_	_
8	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	PBMCs	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	oligomerization	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	CD4	_	NOUN	_	Number=Sing	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	D1/CDR2	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	loop	_	NOUN	_	Number=Sing	_	_	_	_
20	can	_	AUX	_	VerbForm=Fin	_	_	_	_
21	trigger	_	VERB	_	VerbForm=Inf	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	individuals	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001633	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Glycation	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
6	oxygen	_	ADJ	_	Degree=Pos	_	_	_	_
7	species	_	NOUN	_	Number=Plur	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
10	suppression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	insulin	_	ADJ	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	HIT	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Prolonged	_	VERB	_	Degree=Pos	_	_	_	_
2	poor	_	ADJ	_	Degree=Pos	_	_	_	_
3	glycemic	_	ADJ	_	Degree=Pos	_	_	_	_
4	control	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	non-insulin	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	diabetes	_	NOUN	_	Number=Plur	_	_	_	_
10	mellitus	_	ADJ	_	Degree=Pos	_	_	_	_
11	patients	_	NOUN	_	Number=Plur	_	_	_	_
12	often	_	ADV	_	_	_	_	_	_
13	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	decline	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	insulin	_	NOUN	_	Degree=Pos	_	_	_	_
19	secretion	_	NOUN	_	Number=Sing	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	pancreatic	_	ADJ	_	Degree=Pos	_	_	_	_
22	beta	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	accompanied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	decrease	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	insulin	_	ADJ	_	Number=Sing	_	_	_	_
32	content	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	step	_	NOUN	_	Number=Sing	_	_	_	_
4	toward	_	SCONJ	_	_	_	_	_	_
5	elucidating	_	VERB	_	VerbForm=Ger	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	pathophysiological	_	ADJ	_	Degree=Pos	_	_	_	_
8	background	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	so	_	ADV	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	glucose	_	ADJ	_	Number=Sing	_	_	_	_
15	toxicity	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	pancreatic	_	ADJ	_	Degree=Pos	_	_	_	_
18	beta	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
22	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	glycation	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	HIT	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	T15	_	NUM	_	NumType=Card	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	using	_	VERB	_	VerbForm=Ger	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	sugar	_	NOUN	_	Number=Sing	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	strong	_	ADJ	_	Degree=Pos	_	_	_	_
34	deoxidizing	_	NOUN	_	Number=Sing	_	_	_	_
35	activity	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	D	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	ribose	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	effects	_	NOUN	_	Number=Plur	_	_	_	_
45	on	_	ADP	_	_	_	_	_	_
46	insulin	_	ADJ	_	Degree=Pos	_	_	_	_
47	gene	_	NOUN	_	Number=Sing	_	_	_	_
48	transcription	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	reporter	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	analyses	_	NOUN	_	Number=Plur	_	_	_	_
7	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	insulin	_	NOUN	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	more	_	ADV	_	_	_	_	_	_
15	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	glycation	_	NOUN	_	Number=Sing	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	control	_	NOUN	_	Number=Sing	_	_	_	_
21	beta-actin	_	NOUN	_	Degree=Pos	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	;	_	PUNCT	_	_	_	_	_	_
25	approximately	_	ADV	_	_	_	_	_	_
26	50	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	80	_	NUM	_	NumType=Card	_	_	_	_
29	%	_	SYM	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	insulin	_	ADJ	_	Degree=Pos	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	activity	_	NOUN	_	Number=Sing	_	_	_	_
36	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
37	lost	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	when	_	ADV	_	PronType=Int	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
42	kept	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	for	_	ADP	_	_	_	_	_	_
44	3	_	NUM	_	NumType=Card	_	_	_	_
45	d	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	presence	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	40	_	NUM	_	NumType=Card	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	60	_	NUM	_	NumType=Card	_	_	_	_
53	mM	_	NUM	_	Number=Sing	_	_	_	_
54	D	_	NOUN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	ribose	_	NOUN	_	Number=Sing	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	respectively	_	ADV	_	_	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	agreement	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	decrease	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	insulin	_	NOUN	_	Number=Sing	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	insulin	_	ADJ	_	Number=Sing	_	_	_	_
13	content	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	glycation	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Also	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	gel	_	NOUN	_	Number=Sing	_	_	_	_
4	mobility	_	NOUN	_	Number=Sing	_	_	_	_
5	shift	_	NOUN	_	Number=Sing	_	_	_	_
6	analyses	_	NOUN	_	Number=Plur	_	_	_	_
7	using	_	VERB	_	VerbForm=Ger	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	antiserum	_	NOUN	_	Number=Sing	_	_	_	_
10	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	decrease	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	DNA	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	insulin	_	ADJ	_	Degree=Pos	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	PDX-1/IPF1/STF	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	D	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	ribose	_	NOUN	_	Number=Sing	_	_	_	_
7	seemed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	almost	_	ADV	_	_	_	_	_	_
9	irreversible	_	ADJ	_	Degree=Pos	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	could	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	prevented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	addition	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	mM	_	NUM	_	NumType=Card	_	_	_	_
19	aminoguanidine	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	10	_	NUM	_	NumType=Card	_	_	_	_
22	mM	_	NUM	_	Number=Sing	_	_	_	_
23	N	_	NUM	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	acetylcysteine	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	thus	_	ADV	_	_	_	_	_	_
28	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	glycation	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
33	oxygen	_	ADJ	_	Degree=Pos	_	_	_	_
34	species	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	through	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	glycation	_	NOUN	_	Number=Sing	_	_	_	_
40	reaction	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	serve	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
43	as	_	ADP	_	_	_	_	_	_
44	mediators	_	NOUN	_	Number=Plur	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	phenomena	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	glycation	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	pancreatic	_	ADJ	_	Degree=Pos	_	_	_	_
9	beta	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	vivo	_	NOUN	_	Number=Sing	_	_	_	_
16	under	_	ADP	_	_	_	_	_	_
17	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
18	hyperglycemia	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	insulin	_	ADJ	_	Degree=Pos	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	thus	_	ADV	_	_	_	_	_	_
26	can	_	AUX	_	VerbForm=Fin	_	_	_	_
27	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
28	part	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	beta	_	NOUN	_	Number=Sing	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	glucose	_	NOUN	_	Number=Sing	_	_	_	_
34	toxicity	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001634	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Lactobacilli	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	vaginal	_	ADJ	_	Degree=Pos	_	_	_	_
4	host	_	NOUN	_	Number=Sing	_	_	_	_
5	defense	_	NOUN	_	Number=Sing	_	_	_	_
6	:	_	PUNCT	_	_	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
12	virus	_	NOUN	_	Number=Sing	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	long	_	ADJ	_	Degree=Pos	_	_	_	_
16	terminal	_	NOUN	_	Number=Sing	_	_	_	_
17	repeat	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
20	production	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Lactobacilli	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	component	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	normal	_	ADJ	_	Degree=Pos	_	_	_	_
8	vaginal	_	ADJ	_	Degree=Pos	_	_	_	_
9	flora	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	can	_	AUX	_	VerbForm=Fin	_	_	_	_
12	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	long	_	ADJ	_	Degree=Pos	_	_	_	_
23	terminal	_	NOUN	_	Number=Sing	_	_	_	_
24	repeat	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	LTR	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
31	T	_	PROPN	_	Number=Sing	_	_	_	_
32	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	THP	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	lines	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	LTR	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	strongly	_	ADV	_	_	_	_	_	_
10	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	vanadate	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	catalase	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	implicating	_	VERB	_	VerbForm=Ger	_	_	_	_
19	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	THP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	absence	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	vanadate	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	unaffected	_	VERB	_	Degree=Pos	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	catalase	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	active	_	ADJ	_	Degree=Pos	_	_	_	_
3	material	_	NOUN	_	Number=Sing	_	_	_	_
4	partitioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	into	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	phenol	_	NOUN	_	Number=Sing	_	_	_	_
8	layer	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	hot	_	ADJ	_	Degree=Pos	_	_	_	_
11	aqueous	_	ADJ	_	Degree=Pos	_	_	_	_
12	phenol	_	NOUN	_	Number=Sing	_	_	_	_
13	extraction	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Lactobacilli	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	tumor	_	NOUN	_	Number=Sing	_	_	_	_
5	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alphaand	_	NOUN	_	Number=Sing	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1betaproduction	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	THP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	tumor	_	NOUN	_	Number=Sing	_	_	_	_
25	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alphaproduction	_	NOUN	_	Number=Sing	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	vaginal	_	NOUN	_	Degree=Pos	_	_	_	_
3	fluid	_	NOUN	_	Number=Sing	_	_	_	_
4	specimens	_	NOUN	_	Number=Plur	_	_	_	_
5	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
7	properties	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	correlated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
14	content	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	presence	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	vaginal	_	ADJ	_	Degree=Pos	_	_	_	_
8	fluid	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	agent	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	s	_	X	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	indigenous	_	ADJ	_	Degree=Pos	_	_	_	_
17	bacteria	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	can	_	AUX	_	VerbForm=Fin	_	_	_	_
20	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	HIV	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	LTR	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
28	production	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
38	lineage	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	possible	_	ADJ	_	Degree=Pos	_	_	_	_
42	influence	_	NOUN	_	Number=Sing	_	_	_	_
43	on	_	ADP	_	_	_	_	_	_
44	vaginal	_	ADJ	_	Degree=Pos	_	_	_	_
45	physiology	_	NOUN	_	Number=Sing	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	host	_	NOUN	_	Number=Sing	_	_	_	_
48	defense	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001639	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	Tax	_	NOUN	_	Number=Sing	_	_	_	_
8	induction	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
18	kinase	_	NOUN	_	Number=Sing	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	IKKalpha	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	IKKbeta	_	PROPN	_	Number=Sing	_	_	_	_
25	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
26	kinases	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	corresponds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	40	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kDa	_	NOUN	_	Number=Sing	_	_	_	_
8	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	pathogenic	_	ADJ	_	Degree=Pos	_	_	_	_
13	retrovirus	_	NOUN	_	Number=Sing	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
16	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	Rel	_	NOUN	_	Number=Sing	_	_	_	_
36	family	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	factors	_	NOUN	_	Number=Plur	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
43	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	N	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	degradation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	principal	_	ADJ	_	Degree=Pos	_	_	_	_
16	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
17	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	now	_	ADV	_	_	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	Tax	_	NOUN	_	Number=Sing	_	_	_	_
10	activates	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	recently	_	ADV	_	_	_	_	_	_
13	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	kinases	_	NOUN	_	Number=Plur	_	_	_	_
16	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	IKKalpha	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	IKKbeta	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	normally	_	ADV	_	_	_	_	_	_
27	phosphorylate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	on	_	ADP	_	_	_	_	_	_
31	both	_	DET	_	_	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	N	_	ADJ	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
37	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
38	serines	_	NOUN	_	Number=Plur	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	response	_	NOUN	_	Number=Sing	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	tumor	_	NOUN	_	Number=Sing	_	_	_	_
43	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
44	factor	_	NOUN	_	Number=Sing	_	_	_	_
45	alpha	_	NOUN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	TNF	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	alpha	_	NOUN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	1	_	NUM	_	NumType=Card	_	_	_	_
55	(	_	PUNCT	_	_	_	_	_	_
56	IL	_	PROPN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	1	_	NUM	_	NumType=Card	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	mutant	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Tax	_	NOUN	_	Number=Sing	_	_	_	_
8	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	M22	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	fails	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	either	_	CCONJ	_	_	_	_	_	_
23	IKKalpha	_	PROPN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	IKKbeta	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
4	IKK	_	PROPN	_	Number=Sing	_	_	_	_
5	enzymatic	_	ADJ	_	Degree=Pos	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	significantly	_	ADV	_	_	_	_	_	_
9	elevated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1-infected	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	Tax	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Transfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	kinase	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
6	mutants	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IKKalpha	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	IKKbeta	_	PROPN	_	Number=Sing	_	_	_	_
11	into	_	ADP	_	_	_	_	_	_
12	either	_	CCONJ	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	293	_	NUM	_	NumType=Card	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	reporter	_	NOUN	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	Tax	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Similarly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
7	mutant	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NIK	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	kinase	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	TNF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alpha	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	signaling	_	NOUN	_	Number=Sing	_	_	_	_
34	pathways	_	NOUN	_	Number=Plur	_	_	_	_
35	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	IKKalpha	_	PROPN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	IKKbeta	_	PROPN	_	Number=Sing	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	blocks	_	NOUN	_	Number=Plur	_	_	_	_
43	Tax	_	NOUN	_	Number=Sing	_	_	_	_
44	induction	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	NF	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	plasma	_	NOUN	_	Number=Sing	_	_	_	_
4	membrane	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
7	elements	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
10	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
12	pathways	_	NOUN	_	Number=Plur	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	apparently	_	ADV	_	_	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	involved	_	ADJ	_	Degree=Pos	_	_	_	_
17	since	_	ADP	_	_	_	_	_	_
18	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
19	negative	_	ADJ	_	Degree=Pos	_	_	_	_
20	mutants	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	TRAF6	_	NOUN	_	Number=Sing	_	_	_	_
26	adaptors	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	effectively	_	ADV	_	_	_	_	_	_
30	block	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
32	through	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
35	tails	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	TNF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	alpha	_	PROPN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	receptors	_	NOUN	_	Number=Plur	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	respectively	_	ADV	_	_	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
50	not	_	PART	_	_	_	_	_	_
51	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
52	Tax	_	NOUN	_	Number=Sing	_	_	_	_
53	induction	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	NF	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	Tax	_	NOUN	_	Number=Sing	_	_	_	_
11	exploits	_	VERB	_	Number=Plur	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	distal	_	ADJ	_	Degree=Pos	_	_	_	_
14	part	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
19	signaling	_	NOUN	_	Number=Sing	_	_	_	_
20	cascade	_	NOUN	_	Number=Sing	_	_	_	_
21	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	induction	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	pathological	_	ADJ	_	Degree=Pos	_	_	_	_
3	alteration	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
7	pathway	_	NOUN	_	Number=Sing	_	_	_	_
8	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	Tax	_	NOUN	_	Number=Sing	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	play	_	VERB	_	VerbForm=Inf	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	central	_	ADJ	_	Degree=Pos	_	_	_	_
20	role	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
27	transformation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	T	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	clinically	_	ADV	_	_	_	_	_	_
34	manifested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	adult	_	NOUN	_	Number=Sing	_	_	_	_
38	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
39	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001644	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	type	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	B7.1	_	NOUN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	costimulatory	_	ADJ	_	Number=Sing	_	_	_	_
3	molecule	_	NOUN	_	Number=Sing	_	_	_	_
4	B7.	_	PROPN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
9	signal	_	NOUN	_	Number=Sing	_	_	_	_
10	critical	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	T	_	NOUN	_	NumType=Card	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	distribution	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	integral	_	ADJ	_	Degree=Pos	_	_	_	_
6	membrane	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	certain	_	ADJ	_	Degree=Pos	_	_	_	_
12	tissues	_	NOUN	_	Number=Plur	_	_	_	_
13	where	_	ADV	_	PronType=Rel	_	_	_	_
14	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
22	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
23	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	basis	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	specificity	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	chromatin	_	ADJ	_	Degree=Pos	_	_	_	_
13	configuration	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	B7.1	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	intact	_	NOUN	_	Degree=Pos	_	_	_	_
23	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	various	_	ADJ	_	Degree=Pos	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	types	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	identification	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	tissue	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	deoxyribonuclease	_	NOUN	_	Number=Sing	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	hypersensitive	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	approximately	_	ADV	_	_	_	_	_	_
13	3	_	NUM	_	NumType=Card	_	_	_	_
14	kb	_	NOUN	_	Number=Sing	_	_	_	_
15	upstream	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	start	_	NOUN	_	Number=Sing	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	led	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	characterization	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	type	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	specific	_	ADJ	_	Degree=Pos	_	_	_	_
31	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
32	region	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	183	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	bp	_	NOUN	_	Number=Sing	_	_	_	_
5	region	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	both	_	ADV	_	_	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	two	_	NUM	_	NumType=Card	_	_	_	_
15	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
16	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	dibutyryl	_	ADJ	_	Degree=Pos	_	_	_	_
21	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	B7.1	_	PROPN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Deletional	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	site	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
7	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	presence	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
12	functionally	_	ADV	_	_	_	_	_	_
13	critical	_	ADJ	_	Degree=Pos	_	_	_	_
14	cis	_	NOUN	_	Number=Sing	_	_	_	_
15	elements	_	NOUN	_	Number=Plur	_	_	_	_
16	within	_	ADP	_	_	_	_	_	_
17	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
18	region	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	one	_	NUM	_	NumType=Card	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
32	consensus	_	NOUN	_	Number=Sing	_	_	_	_
33	sequence	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	B7.1	_	PROPN	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	positive	_	ADJ	_	Degree=Pos	_	_	_	_
5	B	_	NOUN	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	bound	_	VERB	_	Degree=Pos	_	_	_	_
11	several	_	ADJ	_	Degree=Pos	_	_	_	_
12	members	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	family	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	already	_	ADV	_	_	_	_	_	_
23	implicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	signal	_	ADJ	_	Number=Sing	_	_	_	_
26	transduction	_	NOUN	_	Number=Sing	_	_	_	_
27	pathways	_	NOUN	_	Number=Plur	_	_	_	_
28	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	B7.1	_	NOUN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
5	description	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
9	knowledge	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	elements	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	B7	_	NUM	_	Number=Sing	_	_	_	_
23	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	molecule	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001645	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	Barr	_	PROPN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	EBV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	positive	_	ADJ	_	Degree=Pos	_	_	_	_
14	gastric	_	ADJ	_	Degree=Pos	_	_	_	_
15	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
16	:	_	PUNCT	_	_	_	_	_	_
17	unique	_	ADJ	_	Degree=Pos	_	_	_	_
18	viral	_	ADJ	_	Degree=Pos	_	_	_	_
19	latency	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	tumour	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	case	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	oriented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	evidence	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	association	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Barr	_	PROPN	_	Number=Sing	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	EBV	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	gastric	_	ADJ	_	Degree=Pos	_	_	_	_
19	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
20	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
22	accumulating	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
23	recently	_	ADV	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	interaction	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	s	_	X	_	_	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	between	_	ADP	_	_	_	_	_	_
31	EBV	_	PROPN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	gastric	_	ADJ	_	Degree=Pos	_	_	_	_
34	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	/	_	PUNCT	_	_	_	_	_	_
38	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	largely	_	ADV	_	_	_	_	_	_
40	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	seven	_	NUM	_	NumType=Card	_	_	_	_
8	EBV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	positive	_	ADJ	_	Degree=Pos	_	_	_	_
11	gastric	_	ADJ	_	Degree=Pos	_	_	_	_
12	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
13	tissues	_	NOUN	_	Number=Plur	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	viral	_	ADJ	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
21	level	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	studies	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	EBV	_	NOUN	_	Number=Sing	_	_	_	_
29	oncogenicity	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	will	_	AUX	_	VerbForm=Fin	_	_	_	_
35	benefit	_	VERB	_	VerbForm=Inf	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Reverse	_	NOUN	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	PCR	_	NOUN	_	Number=Sing	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	all	_	DET	_	_	_	_	_	_
9	seven	_	NUM	_	NumType=Card	_	_	_	_
10	EBV	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	positive	_	ADJ	_	Degree=Pos	_	_	_	_
13	tumour	_	NOUN	_	Number=Sing	_	_	_	_
14	tissues	_	NOUN	_	Number=Plur	_	_	_	_
15	constitutively	_	ADV	_	_	_	_	_	_
16	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	EBV	_	PROPN	_	Number=Sing	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	antigen	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	not	_	ADV	_	_	_	_	_	_
28	EBNA2	_	ADJ	_	Number=Sing	_	_	_	_
29	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	initiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	one	_	NUM	_	NumType=Card	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	three	_	NUM	_	NumType=Card	_	_	_	_
10	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
11	promoters	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	Qp	_	NOUN	_	Number=Sing	_	_	_	_
14	:	_	PUNCT	_	_	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	contrast	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	Cp	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	Wp	_	NOUN	_	Number=Sing	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	silent	_	ADJ	_	Degree=Pos	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	thus	_	ADV	_	_	_	_	_	_
26	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	lack	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	EBNA2	_	PROPN	_	Number=Sing	_	_	_	_
32	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Latent	_	ADJ	_	Degree=Pos	_	_	_	_
2	membrane	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	LMP	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	2A	_	NUM	_	Number=Sing	_	_	_	_
8	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	three	_	NUM	_	NumType=Card	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	seven	_	NUM	_	NumType=Card	_	_	_	_
15	cases	_	NOUN	_	Number=Plur	_	_	_	_
16	;	_	PUNCT	_	_	_	_	_	_
17	however	_	ADV	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	neither	_	CCONJ	_	_	_	_	_	_
20	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
21	nor	_	CCONJ	_	_	_	_	_	_
22	LMP2B	_	PROPN	_	Number=Sing	_	_	_	_
23	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	any	_	DET	_	_	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	tumours	_	NOUN	_	Number=Plur	_	_	_	_
31	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Transcripts	_	NOUN	_	Number=Plur	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	BamHI	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	viral	_	ADJ	_	Degree=Pos	_	_	_	_
11	genome	_	NOUN	_	Number=Sing	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	all	_	DET	_	_	_	_	_	_
16	cases	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	BZLF1	_	PROPN	_	Number=Sing	_	_	_	_
2	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	product	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	early	_	ADJ	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	EBV	_	PROPN	_	Number=Sing	_	_	_	_
14	replication	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	any	_	DET	_	_	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	thereby	_	ADV	_	_	_	_	_	_
25	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	tumour	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	carried	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	EBV	_	PROPN	_	Number=Sing	_	_	_	_
32	genomes	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	tightly	_	ADV	_	_	_	_	_	_
36	latent	_	ADJ	_	Degree=Pos	_	_	_	_
37	form	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	further	_	ADV	_	_	_	_	_	_
4	extended	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
6	previous	_	ADJ	_	Degree=Pos	_	_	_	_
7	data	_	NOUN	_	Number=Sing	_	_	_	_
8	regarding	_	VERB	_	VerbForm=Ger	_	_	_	_
9	EBV	_	NOUN	_	Number=Sing	_	_	_	_
10	latency	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	gastric	_	ADJ	_	Degree=Pos	_	_	_	_
13	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	level	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	affirmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	programme	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	viral	_	ADJ	_	Degree=Pos	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	tumour	_	NOUN	_	Number=Sing	_	_	_	_
33	more	_	ADV	_	_	_	_	_	_
34	closely	_	ADV	_	_	_	_	_	_
35	resembles	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	'	_	PUNCT	_	_	_	_	_	_
37	latency	_	NOUN	_	Number=Sing	_	_	_	_
38	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
39	'	_	AUX	_	_	_	_	_	_
40	represented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	Burkitt	_	PROPN	_	Number=Sing	_	_	_	_
43	's	_	PART	_	_	_	_	_	_
44	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
45	than	_	ADP	_	_	_	_	_	_
46	'	_	PUNCT	_	_	_	_	_	_
47	latency	_	NOUN	_	Number=Sing	_	_	_	_
48	II	_	NUM	_	NumType=Card	_	_	_	_
49	'	_	PUNCT	_	_	_	_	_	_
50	represented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	by	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	majority	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	nasopharyngeal	_	ADJ	_	Degree=Pos	_	_	_	_
56	carcinomas	_	NOUN	_	Number=Plur	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001650	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	interaction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	PRE	_	X	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	enhancer	_	VERB	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	4	_	NUM	_	NumType=Card	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	different	_	ADJ	_	Degree=Pos	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	subsets	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	immunomodulatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	cytokine	_	VERB	_	Number=Sing	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	most	_	ADJ	_	_	_	_	_	_
11	hemopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
12	lineages	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	secreted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	Th2	_	NOUN	_	Number=Sing	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	major	_	ADJ	_	Degree=Pos	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	immune	_	ADJ	_	Degree=Pos	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	SCONJ	_	_	_	_	_	_
23	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	naive	_	ADJ	_	Degree=Pos	_	_	_	_
28	Th	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	toward	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	Th2	_	ADJ	_	Degree=Pos	_	_	_	_
33	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	PRE	_	X	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	I	_	PRON	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	essential	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	function	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	tissue	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	PRE	_	X	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
28	site	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	activities	_	NOUN	_	Number=Plur	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
36	factors	_	NOUN	_	Number=Plur	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	4	_	NUM	_	NumType=Card	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	Th1	_	NOUN	_	Number=Sing	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	Th2	_	DET	_	Number=Sing	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	PRE	_	X	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	PMA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	PMA	_	PROPN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	inducible	_	ADJ	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	cyclosporin	_	VERB	_	Number=Sing	_	_	_	_
19	A	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	anti-C	_	NOUN	_	Number=Sing	_	_	_	_
3	/	_	PUNCT	_	_	_	_	_	_
4	EBPbeta	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	IL6	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	anti-C	_	PROPN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	EBPdelta	_	PROPN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	IL6beta	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	anti-NF	_	ADJ	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	ATc	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	anti-NF	_	ADJ	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	ATp	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	anti-Fos	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	anti-Jun	_	ADJ	_	Degree=Pos	_	_	_	_
32	Abs	_	PROPN	_	Number=Sing	_	_	_	_
33	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
34	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	that	_	SCONJ	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	previously	_	ADV	_	_	_	_	_	_
38	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	PRE	_	X	_	_	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
42	binding	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
43	factor	_	NOUN	_	Number=Sing	_	_	_	_
44	POS	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
48	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	different	_	ADJ	_	Degree=Pos	_	_	_	_
51	transcription	_	NOUN	_	Number=Sing	_	_	_	_
52	factors	_	NOUN	_	Number=Plur	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	different	_	ADJ	_	Degree=Pos	_	_	_	_
55	Th	_	NOUN	_	NumType=Card	_	_	_	_
56	cell	_	NOUN	_	Number=Sing	_	_	_	_
57	subsets	_	NOUN	_	Number=Plur	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	IL-4	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	Th0	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	like	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	Jurkat	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	mouse	_	NOUN	_	Number=Sing	_	_	_	_
13	EL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	POS	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	POS	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1a	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	IL6beta	_	PROPN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	Jun	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	mouse	_	NOUN	_	Number=Sing	_	_	_	_
4	Th2	_	DET	_	Number=Sing	_	_	_	_
5	D10	_	NUM	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	Th2	_	NOUN	_	Number=Sing	_	_	_	_
12	clones	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	POS	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	POS	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1b	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	IL6beta	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	Jun	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	ATc	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	p	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	POS	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	extracts	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	Th1	_	NOUN	_	Number=Sing	_	_	_	_
16	clones	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	PRE	_	X	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	play	_	VERB	_	VerbForm=Inf	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	differential	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	4	_	NUM	_	NumType=Card	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	levels	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001654	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
7	acid	_	NOUN	_	Number=Sing	_	_	_	_
8	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	AP1	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
19	acid	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	type	_	NOUN	_	Number=Sing	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	2A	_	NOUN	_	Number=Sing	_	_	_	_
28	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
32	extracts	_	NOUN	_	Number=Plur	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	presence	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	AP1	_	NOUN	_	Number=Sing	_	_	_	_
40	as	_	ADP	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	measure	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	early	_	ADJ	_	Degree=Pos	_	_	_	_
45	T	_	NOUN	_	Number=Sing	_	_	_	_
46	cell	_	NOUN	_	Number=Sing	_	_	_	_
47	activation	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Okadaic	_	PROPN	_	Number=Sing	_	_	_	_
2	acid	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	potent	_	ADJ	_	Degree=Pos	_	_	_	_
9	inducer	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	AP1	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
5	esters	_	NOUN	_	Number=Plur	_	_	_	_
6	such	_	ADJ	_	Degree=Pos	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
9	myristate	_	NOUN	_	Number=Sing	_	_	_	_
10	acetate	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	PMA	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	AP1	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
21	acid	_	NOUN	_	Number=Sing	_	_	_	_
22	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	predominantly	_	ADV	_	_	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	jun	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	fos	_	ADP	_	Number=Sing	_	_	_	_
32	family	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	proto	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Surprisingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	while	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	addition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
8	further	_	ADV	_	_	_	_	_	_
9	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	AP1	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	addition	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	PMA	_	PROPN	_	Number=Sing	_	_	_	_
19	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Okadaic	_	PROPN	_	Number=Sing	_	_	_	_
2	acid	_	NOUN	_	Number=Sing	_	_	_	_
3	treatment	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	dramatically	_	ADV	_	_	_	_	_	_
8	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	jun	_	NOUN	_	Number=Sing	_	_	_	_
14	family	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	proto	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
19	including	_	VERB	_	VerbForm=Ger	_	_	_	_
20	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	junD	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	junB	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	lesser	_	ADJ	_	Degree=Cmp	_	_	_	_
30	extent	_	NOUN	_	Number=Sing	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	fos	_	NOUN	_	Number=Sing	_	_	_	_
33	family	_	NOUN	_	Number=Sing	_	_	_	_
34	including	_	VERB	_	VerbForm=Ger	_	_	_	_
35	c	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	fos	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	fra	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	comparison	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	PMA	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	very	_	ADV	_	_	_	_	_	_
8	inefficient	_	ADJ	_	Degree=Pos	_	_	_	_
9	inducer	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	jun	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	family	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	AP1	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	okadaic	_	PROPN	_	Number=Sing	_	_	_	_
12	acid	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	PMA	_	PROPN	_	Number=Sing	_	_	_	_
15	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	c	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	jun	_	NOUN	_	Number=Sing	_	_	_	_
22	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
25	acid	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Transfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	c	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	jun	_	NOUN	_	Number=Sing	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	constructs	_	NOUN	_	Number=Plur	_	_	_	_
8	confirmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	difference	_	NOUN	_	Number=Sing	_	_	_	_
12	between	_	ADP	_	_	_	_	_	_
13	PMA	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
16	acid	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	SCONJ	_	_	_	_	_	_
18	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	c	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	jun	_	NOUN	_	Number=Sing	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	AP1	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
7	acid	_	NOUN	_	Number=Sing	_	_	_	_
8	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	2A	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	PP1	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	PP2A	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	involved	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	T	_	PROPN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	important	_	ADJ	_	Degree=Pos	_	_	_	_
29	negative	_	ADJ	_	Degree=Pos	_	_	_	_
30	regulators	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	factor	_	NOUN	_	Number=Sing	_	_	_	_
35	AP1	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001656	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	anoxia	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	reoxygenation	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
10	adherence	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	objectives	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	1	_	X	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	time	_	NOUN	_	Number=Sing	_	_	_	_
14	course	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	neutrophil	_	NOUN	_	Degree=Pos	_	_	_	_
17	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	monolayers	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
23	vein	_	NOUN	_	Number=Sing	_	_	_	_
24	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	exposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	60	_	NUM	_	NumType=Card	_	_	_	_
34	minutes	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	anoxia	_	NOUN	_	Number=Sing	_	_	_	_
37	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	30	_	NUM	_	NumType=Card	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	600	_	NUM	_	NumType=Card	_	_	_	_
42	minutes	_	NOUN	_	Number=Plur	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	reoxygenation	_	NOUN	_	Number=Sing	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	2	_	X	_	_	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	define	_	VERB	_	VerbForm=Inf	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
52	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
53	for	_	ADP	_	_	_	_	_	_
54	both	_	CCONJ	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	early	_	ADJ	_	Degree=Pos	_	_	_	_
57	(	_	PUNCT	_	_	_	_	_	_
58	minutes	_	NOUN	_	Number=Plur	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	and	_	CCONJ	_	_	_	_	_	_
61	late	_	ADJ	_	Degree=Pos	_	_	_	_
62	(	_	PUNCT	_	_	_	_	_	_
63	hours	_	NOUN	_	Number=Plur	_	_	_	_
64	)	_	PUNCT	_	_	_	_	_	_
65	hyperadhesivity	_	NOUN	_	Number=Sing	_	_	_	_
66	of	_	ADP	_	_	_	_	_	_
67	postanoxic	_	ADJ	_	Degree=Pos	_	_	_	_
68	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
69	to	_	ADP	_	_	_	_	_	_
70	human	_	ADJ	_	Degree=Pos	_	_	_	_
71	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
72	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	clearly	_	ADV	_	_	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	anoxia	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	reoxygenation	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	A	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	R	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
18	increase	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
21	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	with	_	SCONJ	_	_	_	_	_	_
26	peak	_	NOUN	_	Number=Sing	_	_	_	_
27	responses	_	NOUN	_	Number=Plur	_	_	_	_
28	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
29	at	_	ADP	_	_	_	_	_	_
30	30	_	NUM	_	NumType=Card	_	_	_	_
31	minutes	_	NOUN	_	Number=Plur	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	phase	_	NOUN	_	Number=Sing	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	240	_	NUM	_	NumType=Card	_	_	_	_
38	minutes	_	NOUN	_	Number=Plur	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	phase	_	NOUN	_	Number=Sing	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	after	_	ADP	_	_	_	_	_	_
44	reoxygenation	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Oxypurinol	_	ADJ	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	catalase	_	NOUN	_	Number=Sing	_	_	_	_
4	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	phase	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	xanthine	_	NOUN	_	Number=Sing	_	_	_	_
15	oxidase	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	comparison	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	platelet	_	NOUN	_	Number=Sing	_	_	_	_
5	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	PAF	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	contributed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	both	_	DET	_	_	_	_	_	_
13	phases	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
16	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Anti-intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
3	molecule	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	anti-P	_	ADJ	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	selectin	_	NOUN	_	Number=Sing	_	_	_	_
15	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
18	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
19	[	_	PUNCT	_	_	_	_	_	_
20	mAbs	_	NOUN	_	Number=Plur	_	_	_	_
21	]	_	PUNCT	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	attenuated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	phase	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	neutrophil	_	NOUN	_	Degree=Pos	_	_	_	_
28	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	roles	_	NOUN	_	Number=Plur	_	_	_	_
33	for	_	ADP	_	_	_	_	_	_
34	constitutively	_	ADV	_	_	_	_	_	_
35	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	surface	_	NOUN	_	Number=Sing	_	_	_	_
42	expression	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	preformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	P-selectin	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Phase	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
5	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	attenuated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	anti-E	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	selectin	_	NOUN	_	Number=Sing	_	_	_	_
13	mAb	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
18	role	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
22	molecule	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	late	_	ADJ	_	Degree=Pos	_	_	_	_
26	phase	_	NOUN	_	Number=Sing	_	_	_	_
27	response	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	actinomycin	_	NOUN	_	Number=Sing	_	_	_	_
4	D	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	with	_	SCONJ	_	_	_	_	_	_
9	competing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	ds	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
13	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	activator	_	NOUN	_	Number=Sing	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	cognate	_	ADJ	_	Number=Sing	_	_	_	_
26	DNA	_	PROPN	_	Number=Sing	_	_	_	_
27	sequences	_	NOUN	_	Number=Plur	_	_	_	_
28	significantly	_	ADV	_	_	_	_	_	_
29	attenuated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	phase	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	response	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	role	_	NOUN	_	Number=Sing	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	de	_	X	_	Number=Sing	_	_	_	_
40	novo	_	X	_	Number=Sing	_	_	_	_
41	macromolecule	_	NOUN	_	Number=Sing	_	_	_	_
42	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Surface	_	NOUN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	P-	_	NOUN	_	Number=Sing	_	_	_	_
9	selectin	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	E-selectin	_	NOUN	_	Number=Sing	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	HUVECs	_	NOUN	_	Number=Sing	_	_	_	_
15	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	phase	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	-	_	SYM	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
25	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
26	responses	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Collectively	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	findings	_	NOUN	_	Number=Plur	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	A/R	_	NOUN	_	Number=Sing	_	_	_	_
8	elicits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	phase	_	NOUN	_	Number=Sing	_	_	_	_
13	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	independent	_	ADJ	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	surface	_	NOUN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	different	_	ADJ	_	Degree=Pos	_	_	_	_
32	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
35	molecules	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001658	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Costimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	CD4	_	NOUN	_	Number=Sing	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	LFA	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	B7	_	PROPN	_	Number=Sing	_	_	_	_
9	induce	_	VERB	_	Number=Sing	_	_	_	_
10	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
11	effects	_	NOUN	_	Number=Plur	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	earlier	_	ADV	_	Degree=Cmp	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	DET	_	_	_	_	_	_
6	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	CD4	_	NOUN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	SEA	_	NOUN	_	Number=Sing	_	_	_	_
5	presented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	Chinese	_	ADJ	_	Degree=Pos	_	_	_	_
8	hamster	_	NOUN	_	Number=Sing	_	_	_	_
9	ovary	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	CHO	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	DR	_	NOUN	_	Number=Sing	_	_	_	_
15	transfectants	_	NOUN	_	Number=Plur	_	_	_	_
16	coexpressing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	either	_	CCONJ	_	_	_	_	_	_
18	B7	_	PROPN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	LFA	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	3	_	NUM	_	NumType=Card	_	_	_	_
23	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
26	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
27	profiles	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	B7	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	but	_	CCONJ	_	_	_	_	_	_
8	not	_	ADV	_	_	_	_	_	_
9	LFA	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	strongly	_	ADV	_	_	_	_	_	_
14	costimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	CD4	_	PROPN	_	Number=Sing	_	_	_	_
24	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	Maximal	_	ADJ	_	Number=Sing	_	_	_	_
2	increase	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	recorded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	CHO	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	DR	_	PROPN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	B7	_	PROPN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	LFA	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	cooperative	_	ADJ	_	Degree=Pos	_	_	_	_
24	effect	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	B7	_	PROPN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	LFA	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	at	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
34	level	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	CD4	_	NOUN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	CHO	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	DR	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	staphylococcal	_	ADJ	_	Number=Sing	_	_	_	_
9	enterotoxin	_	NOUN	_	Number=Sing	_	_	_	_
10	A	_	PROPN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
15	significant	_	ADJ	_	Degree=Pos	_	_	_	_
16	amounts	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	whereas	_	SCONJ	_	_	_	_	_	_
26	induction	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	AP	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	binding	_	VERB	_	Number=Sing	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	LFA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	moderate	_	ADJ	_	Degree=Pos	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	AP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	SYM	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	levels	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	while	_	SCONJ	_	_	_	_	_	_
25	B7	_	PROPN	_	Number=Sing	_	_	_	_
26	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
27	strongly	_	ADV	_	_	_	_	_	_
28	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	both	_	CCONJ	_	_	_	_	_	_
30	AP	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	substantially	_	ADV	_	_	_	_	_	_
35	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappa	_	NOUN	_	Number=Sing	_	_	_	_
39	B	_	NOUN	_	Number=Sing	_	_	_	_
40	binding	_	NOUN	_	Number=Sing	_	_	_	_
41	proteins	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CHO-DR	_	NOUN	_	Number=Sing	_	_	_	_
3	/	_	PUNCT	_	_	_	_	_	_
4	B7	_	PROPN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	LFA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	triple	_	NOUN	_	Number=Sing	_	_	_	_
10	transfectant	_	NOUN	_	Number=Sing	_	_	_	_
11	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	further	_	ADJ	_	Degree=Pos	_	_	_	_
14	increase	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	AP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	binding	_	VERB	_	Number=Sing	_	_	_	_
25	proteins	_	NOUN	_	Number=Plur	_	_	_	_
26	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	double	_	ADJ	_	Degree=Pos	_	_	_	_
30	transfectants	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	level	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Oct	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	similar	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	all	_	DET	_	_	_	_	_	_
13	samples	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Super	_	ADJ	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	complex	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	costimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	CD4	_	PROPN	_	Number=Sing	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	large	_	ADJ	_	Degree=Pos	_	_	_	_
5	amounts	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	p50	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
10	amounts	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	p65	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	marginal	_	ADJ	_	Degree=Pos	_	_	_	_
16	levels	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	c	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	Rel	_	NOUN	_	Number=Sing	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	AP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	proteins	_	NOUN	_	Number=Plur	_	_	_	_
7	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	c-	_	PUNCT	_	_	_	_	_	_
9	Jun	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	Jun-D	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	Fra-1	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	marginal	_	ADJ	_	Degree=Pos	_	_	_	_
18	amounts	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Jun	_	PROPN	_	Number=Sing	_	_	_	_
21	-B	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	B7	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	LFA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	AP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	PROPN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	partly	_	ADV	_	_	_	_	_	_
4	account	_	VERB	_	VerbForm=Inf	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	differential	_	ADJ	_	Degree=Pos	_	_	_	_
8	effects	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	B7	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	LFA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	3	_	NUM	_	NumType=Card	_	_	_	_
15	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001660	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	heat	_	NOUN	_	Number=Sing	_	_	_	_
15	shock	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	heat	_	NOUN	_	Number=Sing	_	_	_	_
5	shock	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	protooncogenes	_	NOUN	_	Number=Plur	_	_	_	_
13	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	c	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	jun	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	c-myc	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Heat	_	NOUN	_	Number=Sing	_	_	_	_
2	shock	_	NOUN	_	Number=Sing	_	_	_	_
3	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	increase	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	c	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	fos	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	c	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	jun	_	X	_	Number=Sing	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	decrease	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
21	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
22	levels	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	pre-B	_	PROPN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	Hyon	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	T	_	PROPN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	DND	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	41	_	NUM	_	NumType=Card	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	lines	_	NOUN	_	Number=Plur	_	_	_	_
37	as	_	ADV	_	_	_	_	_	_
38	well	_	ADV	_	Degree=Pos	_	_	_	_
39	as	_	ADP	_	_	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	freshly	_	ADV	_	_	_	_	_	_
42	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	normal	_	ADJ	_	Degree=Pos	_	_	_	_
44	human	_	ADJ	_	Degree=Pos	_	_	_	_
45	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	changes	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	protooncogenes	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	Hyon	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	most	_	ADV	_	_	_	_	_	_
15	pronounced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	42	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	43	_	NUM	_	NumType=Card	_	_	_	_
20	degrees	_	NOUN	_	Number=Plur	_	_	_	_
21	C	_	NOUN	_	Number=Sing	_	_	_	_
22	;	_	PUNCT	_	_	_	_	_	_
23	kinetic	_	ADJ	_	Degree=Pos	_	_	_	_
24	analysis	_	NOUN	_	Number=Sing	_	_	_	_
25	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	changes	_	NOUN	_	Number=Plur	_	_	_	_
29	could	_	AUX	_	VerbForm=Fin	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	within	_	ADP	_	_	_	_	_	_
33	30	_	NUM	_	NumType=Card	_	_	_	_
34	min	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	heat	_	NOUN	_	Number=Sing	_	_	_	_
37	shock	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Altered	_	VERB	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	fos	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	primary	_	ADJ	_	Degree=Pos	_	_	_	_
13	effect	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	heat	_	NOUN	_	Number=Sing	_	_	_	_
16	shock	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Secondarily	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	heat	_	NOUN	_	Number=Sing	_	_	_	_
4	shock	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Hyon	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	stabilized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	level	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	half	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	life	_	NOUN	_	Number=Sing	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	24	_	NUM	_	NumType=Card	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	45	_	NUM	_	NumType=Card	_	_	_	_
23	min	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	overall	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	heat	_	NOUN	_	Number=Sing	_	_	_	_
6	shock	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	level	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	however	_	ADV	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	protooncogenes	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	heat	_	NOUN	_	Number=Sing	_	_	_	_
14	shock	_	NOUN	_	Number=Sing	_	_	_	_
15	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	protooncogenes	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	stress	_	NOUN	_	Number=Sing	_	_	_	_
24	response	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001663	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Blockade	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	dithiocarbamates	_	NOUN	_	Number=Plur	_	_	_	_
7	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	novel	_	NOUN	_	Number=Sing	_	_	_	_
9	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Dithiocarbamates	_	PROPN	_	Number=Plur	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	DTCs	_	NOUN	_	Number=Plur	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	recently	_	ADV	_	_	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	powerful	_	ADJ	_	Degree=Pos	_	_	_	_
11	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	number	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	types	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Given	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	role	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
23	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
25	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	as	_	ADP	_	_	_	_	_	_
27	potential	_	ADJ	_	Degree=Pos	_	_	_	_
28	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
29	drugs	_	NOUN	_	Number=Plur	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
32	diseases	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	DTCs	_	PROPN	_	Number=Sing	_	_	_	_
6	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	both	_	CCONJ	_	_	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	_	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	membrane	_	ADJ	_	Degree=Pos	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	antigens	_	NOUN	_	Number=Plur	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	during	_	ADP	_	_	_	_	_	_
25	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	parallel	_	ADJ	_	Degree=Pos	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	c	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	Jun	_	PROPN	_	Number=Sing	_	_	_	_
14	transactivating	_	NOUN	_	Degree=Pos	_	_	_	_
15	functions	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	reflected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	transfection	_	NOUN	_	Number=Sing	_	_	_	_
23	experiments	_	NOUN	_	Number=Plur	_	_	_	_
24	at	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	level	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	involved	_	ADJ	_	Degree=Pos	_	_	_	_
34	not	_	ADV	_	_	_	_	_	_
35	only	_	ADV	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	reporter	_	NOUN	_	Number=Sing	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	but	_	CCONJ	_	_	_	_	_	_
47	also	_	ADV	_	_	_	_	_	_
48	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
51	factor	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
54	T	_	NOUN	_	Number=Sing	_	_	_	_
55	cells	_	NOUN	_	Number=Plur	_	_	_	_
56	(	_	PUNCT	_	_	_	_	_	_
57	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
58	)	_	PUNCT	_	_	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Accordingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
4	mobility	_	NOUN	_	Number=Sing	_	_	_	_
5	shift	_	NOUN	_	Number=Sing	_	_	_	_
6	assays	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	EMSAs	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	pyrrolidine	_	NOUN	_	Number=Sing	_	_	_	_
13	DTC	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	NFAT	_	ADJ	_	Degree=Pos	_	_	_	_
24	DNA	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	binding	_	VERB	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	T	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	either	_	CCONJ	_	_	_	_	_	_
34	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
35	myristate	_	NOUN	_	Number=Sing	_	_	_	_
36	acetate	_	NOUN	_	Number=Sing	_	_	_	_
37	plus	_	CCONJ	_	_	_	_	_	_
38	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
39	or	_	CCONJ	_	_	_	_	_	_
40	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
41	against	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	CD3-T	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	cell	_	NOUN	_	Number=Sing	_	_	_	_
46	receptor	_	NOUN	_	Number=Sing	_	_	_	_
47	complex	_	NOUN	_	Number=Sing	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	simultaneously	_	ADV	_	_	_	_	_	_
50	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	binding	_	NOUN	_	Number=Sing	_	_	_	_
53	of	_	ADP	_	_	_	_	_	_
54	AP	_	NOUN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	1	_	NUM	_	NumType=Card	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_
58	Furthermore	_	ADV	_	_	_	_	_	_
59	,	_	PUNCT	_	_	_	_	_	_
60	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
61	differentially	_	ADV	_	_	_	_	_	_
62	targeted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
63	both	_	CCONJ	_	_	_	_	_	_
64	NFATp	_	PROPN	_	Number=Sing	_	_	_	_
65	and	_	CCONJ	_	_	_	_	_	_
66	NFATc	_	PROPN	_	Degree=Pos	_	_	_	_
67	family	_	NOUN	_	Number=Sing	_	_	_	_
68	members	_	NOUN	_	Number=Plur	_	_	_	_
69	,	_	PUNCT	_	_	_	_	_	_
70	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
71	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
72	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
73	functions	_	NOUN	_	Number=Plur	_	_	_	_
74	of	_	ADP	_	_	_	_	_	_
75	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
76	and	_	CCONJ	_	_	_	_	_	_
77	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
78	induction	_	NOUN	_	Number=Sing	_	_	_	_
79	of	_	ADP	_	_	_	_	_	_
80	NFATc	_	NOUN	_	Number=Sing	_	_	_	_
81	.	_	PUNCT	_	_	_	_	_	_

1	Strikingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Western	_	ADJ	_	Degree=Pos	_	_	_	_
4	blotting	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	immunocytochemical	_	ADJ	_	Degree=Pos	_	_	_	_
7	experiments	_	NOUN	_	Number=Plur	_	_	_	_
8	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	PDTC	_	NOUN	_	Number=Sing	_	_	_	_
11	promoted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	transient	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
16	shuttling	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	NFATc	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	accelerated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	export	_	NOUN	_	Number=Sing	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
12	could	_	AUX	_	VerbForm=Fin	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
18	shuttling	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	therefore	_	ADV	_	_	_	_	_	_
24	transiently	_	ADV	_	_	_	_	_	_
25	converting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	that	_	PRON	_	PronType=Rel	_	_	_	_
34	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	during	_	ADP	_	_	_	_	_	_
36	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
41	that	_	SCONJ	_	_	_	_	_	_
42	c-Jun	_	PROPN	_	Number=Sing	_	_	_	_
43	NH2	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	terminal	_	NOUN	_	Number=Sing	_	_	_	_
46	kinase	_	NOUN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	JNK	_	PROPN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	can	_	AUX	_	VerbForm=Fin	_	_	_	_
51	act	_	VERB	_	VerbForm=Inf	_	_	_	_
52	by	_	ADP	_	_	_	_	_	_
53	directly	_	ADV	_	_	_	_	_	_
54	phosphorylating	_	VERB	_	VerbForm=Ger	_	_	_	_
55	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	KB	_	PROPN	_	Number=Sing	_	_	_	_
14	support	_	VERB	_	Number=Sing	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	potential	_	ADJ	_	Degree=Pos	_	_	_	_
17	use	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	DTCs	_	NOUN	_	Number=Plur	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	immunosuppressants	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001666	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	mechanical	_	ADJ	_	Degree=Pos	_	_	_	_
7	ventilation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	vitro	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Positive	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	pressure	_	NOUN	_	Number=Sing	_	_	_	_
4	mechanical	_	ADJ	_	Degree=Pos	_	_	_	_
5	ventilation	_	NOUN	_	Number=Sing	_	_	_	_
6	supports	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	gas	_	NOUN	_	Number=Sing	_	_	_	_
8	exchange	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	patients	_	NOUN	_	Number=Plur	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	respiratory	_	ADJ	_	Degree=Pos	_	_	_	_
13	failure	_	NOUN	_	Number=Sing	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	also	_	ADV	_	_	_	_	_	_
17	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	significant	_	ADJ	_	Degree=Pos	_	_	_	_
20	lung	_	NOUN	_	Number=Sing	_	_	_	_
21	injury	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	developed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vitro	_	NOUN	_	Number=Sing	_	_	_	_
11	model	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	lung	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	can	_	AUX	_	VerbForm=Fin	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	submitted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	prolonged	_	VERB	_	Degree=Pos	_	_	_	_
23	cyclic	_	ADJ	_	Degree=Pos	_	_	_	_
24	pressure	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	stretching	_	VERB	_	VerbForm=Ger	_	_	_	_
27	strain	_	NOUN	_	Number=Sing	_	_	_	_
28	resembling	_	VERB	_	VerbForm=Ger	_	_	_	_
29	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	conventional	_	ADJ	_	Degree=Pos	_	_	_	_
32	mechanical	_	ADJ	_	Degree=Pos	_	_	_	_
33	ventilation	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	model	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	Silastic	_	ADJ	_	Degree=Pos	_	_	_	_
10	membrane	_	NOUN	_	Number=Sing	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	elongated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	up	_	ADP	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	7	_	NUM	_	NumType=Card	_	_	_	_
16	%	_	SYM	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	initial	_	ADJ	_	Degree=Pos	_	_	_	_
20	diameter	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	12	_	NUM	_	NumType=Card	_	_	_	_
26	%	_	SYM	_	Number=Sing	_	_	_	_
27	increase	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	surface	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	lung	_	NOUN	_	Number=Sing	_	_	_	_
3	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	main	_	ADJ	_	Degree=Pos	_	_	_	_
9	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	source	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	critical	_	ADJ	_	Degree=Pos	_	_	_	_
13	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	mediators	_	NOUN	_	Number=Plur	_	_	_	_
15	such	_	ADJ	_	Degree=Pos	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	tumor	_	NOUN	_	Number=Sing	_	_	_	_
18	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	chemokines	_	NOUN	_	Number=Plur	_	_	_	_
25	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	-8	_	NUM	_	NumType=Card	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	-	_	SYM	_	_	_	_	_	_
32	6	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	matrix	_	NOUN	_	Number=Sing	_	_	_	_
36	metalloproteinase	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	9	_	NUM	_	NumType=Card	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
41	model	_	NOUN	_	Number=Sing	_	_	_	_
42	system	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	mechanical	_	ADJ	_	Degree=Pos	_	_	_	_
45	ventilation	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	mediators	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	supernatants	_	NOUN	_	Number=Plur	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	ventilated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
10	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	THP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	ventilated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
2	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	mechanical	_	ADJ	_	Degree=Pos	_	_	_	_
6	stress	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	molecules	_	NOUN	_	Number=Plur	_	_	_	_
9	such	_	ADJ	_	Degree=Pos	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
12	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	mechanical	_	ADJ	_	Degree=Pos	_	_	_	_
19	ventilation	_	NOUN	_	Number=Sing	_	_	_	_
20	might	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	particularly	_	ADV	_	_	_	_	_	_
23	deleterious	_	ADJ	_	Degree=Pos	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	preinjured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	lungs	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
2	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	8	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	tumor	_	NOUN	_	Number=Sing	_	_	_	_
8	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	secretion	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	ventilated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Mechanical	_	ADJ	_	Degree=Pos	_	_	_	_
2	ventilation	_	NOUN	_	Number=Sing	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	low	_	ADJ	_	Degree=Pos	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	8	_	NUM	_	NumType=Card	_	_	_	_
10	secretion	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	alveolar	_	NOUN	_	Degree=Pos	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	II	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	like	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Other	_	ADJ	_	Degree=Pos	_	_	_	_
2	lung	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	types	_	NOUN	_	Number=Plur	_	_	_	_
5	such	_	ADJ	_	Degree=Pos	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	bronchial	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
15	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	8	_	NUM	_	NumType=Card	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	prolonged	_	VERB	_	Degree=Pos	_	_	_	_
26	cyclic	_	ADJ	_	Degree=Pos	_	_	_	_
27	pressure	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	stretching	_	VERB	_	VerbForm=Ger	_	_	_	_
30	load	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	model	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	particular	_	ADJ	_	Degree=Pos	_	_	_	_
6	value	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	SCONJ	_	_	_	_	_	_
8	exploring	_	VERB	_	VerbForm=Ger	_	_	_	_
9	physical	_	ADJ	_	Degree=Pos	_	_	_	_
10	stress	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	signaling	_	NOUN	_	Number=Sing	_	_	_	_
14	pathways	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	as	_	ADV	_	_	_	_	_	_
17	well	_	ADV	_	Degree=Pos	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	for	_	SCONJ	_	_	_	_	_	_
20	testing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	effects	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	novel	_	NOUN	_	Number=Sing	_	_	_	_
25	ventilatory	_	ADJ	_	Degree=Pos	_	_	_	_
26	strategies	_	NOUN	_	Number=Plur	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	adjunctive	_	ADJ	_	Degree=Pos	_	_	_	_
29	substances	_	NOUN	_	Number=Plur	_	_	_	_
30	aimed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	at	_	ADP	_	_	_	_	_	_
32	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	mechanical	_	ADJ	_	Degree=Pos	_	_	_	_
38	ventilation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001669	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Murine	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	T-lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
5	GATA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	3	_	NUM	_	NumType=Card	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	mediate	_	VERB	_	Degree=Pos	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	cis	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	within	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	delta	_	NOUN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	family	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	activators	_	NOUN	_	Number=Plur	_	_	_	_
6	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	recently	_	ADV	_	_	_	_	_	_
8	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
9	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	chickens	_	NOUN	_	Number=Plur	_	_	_	_
12	;	_	PUNCT	_	_	_	_	_	_
13	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	activators	_	NOUN	_	Number=Plur	_	_	_	_
16	recognize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	common	_	ADJ	_	Degree=Pos	_	_	_	_
19	consensus	_	NOUN	_	Number=Sing	_	_	_	_
20	motif	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	WGATAR	_	ADJ	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	through	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	conserved	_	ADJ	_	Degree=Pos	_	_	_	_
27	C4	_	PROPN	_	Number=Sing	_	_	_	_
28	zinc	_	NOUN	_	Number=Sing	_	_	_	_
29	finger	_	NOUN	_	Number=Sing	_	_	_	_
30	DNA	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	binding	_	VERB	_	Number=Sing	_	_	_	_
33	domain	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	members	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	multigene	_	ADJ	_	Number=Sing	_	_	_	_
8	family	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	cGATA	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	most	_	ADV	_	_	_	_	_	_
16	abundantly	_	ADV	_	_	_	_	_	_
17	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	T-lymphocyte	_	PROPN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	lineage	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	murine	_	NOUN	_	Number=Sing	_	_	_	_
6	GATA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	factors	_	NOUN	_	Number=Plur	_	_	_	_
10	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	striking	_	ADJ	_	Degree=Pos	_	_	_	_
13	degree	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	amino	_	ADJ	_	Degree=Pos	_	_	_	_
16	acid	_	NOUN	_	Number=Sing	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	identity	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	similar	_	ADJ	_	Degree=Pos	_	_	_	_
21	patterns	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	tissue	_	NOUN	_	Number=Sing	_	_	_	_
24	specificity	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	three	_	NUM	_	NumType=Card	_	_	_	_
30	organisms	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	murine	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	abundantly	_	ADV	_	_	_	_	_	_
8	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	variety	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	murine	_	VERB	_	Number=Sing	_	_	_	_
16	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
17	lines	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	can	_	AUX	_	VerbForm=Fin	_	_	_	_
20	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	through	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	tissue	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	GATA	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	site	_	NOUN	_	Number=Sing	_	_	_	_
31	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	within	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	human	_	ADJ	_	Degree=Pos	_	_	_	_
35	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
36	receptor	_	NOUN	_	Number=Sing	_	_	_	_
37	delta	_	NOUN	_	Number=Sing	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	infer	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	murine	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	GATA	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	central	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	highly	_	ADV	_	_	_	_	_	_
17	conserved	_	ADJ	_	Degree=Pos	_	_	_	_
18	role	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	vertebrate	_	ADJ	_	Degree=Pos	_	_	_	_
21	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	regulation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001671	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
2	growth	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_

1	Ig	_	NOUN	_	Number=Sing	_	_	_	_
2	production	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	SCONJ	_	_	_	_	_	_
4	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
5	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	switch	_	NOUN	_	Number=Sing	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	membrane	_	NOUN	_	Number=Sing	_	_	_	_
12	form	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	form	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	Ig	_	ADJ	_	Number=Sing	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
2	growth	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	TGF	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	beta	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	inhibits	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	Ig	_	NOUN	_	Number=Sing	_	_	_	_
15	secretion	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	membrane	_	NOUN	_	Number=Sing	_	_	_	_
21	Ig	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TGF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	lymphocyte	_	NOUN	_	Degree=Pos	_	_	_	_
11	cultures	_	NOUN	_	Number=Plur	_	_	_	_
12	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	Staphylococcus	_	PROPN	_	Number=Sing	_	_	_	_
15	aureus	_	PROPN	_	Number=Sing	_	_	_	_
16	Cowan	_	PROPN	_	Number=Sing	_	_	_	_
17	strain	_	NOUN	_	Number=Sing	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	completely	_	ADV	_	_	_	_	_	_
24	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	B	_	PROPN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	Ig	_	NOUN	_	Number=Sing	_	_	_	_
28	secretion	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
31	than	_	ADP	_	_	_	_	_	_
32	90	_	NUM	_	NumType=Card	_	_	_	_
33	%	_	SYM	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	surface	_	NOUN	_	Number=Sing	_	_	_	_
40	IgM	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	IgD	_	PROPN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	kappa	_	PROPN	_	Number=Sing	_	_	_	_
45	L	_	PROPN	_	Number=Sing	_	_	_	_
46	chain	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	lambda	_	NOUN	_	Number=Sing	_	_	_	_
50	L	_	PROPN	_	Number=Sing	_	_	_	_
51	chain	_	NOUN	_	Number=Sing	_	_	_	_
52	expression	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	TGF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	only	_	ADV	_	_	_	_	_	_
9	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
10	effects	_	NOUN	_	Number=Plur	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	two	_	NUM	_	NumType=Card	_	_	_	_
13	other	_	ADJ	_	Degree=Pos	_	_	_	_
14	B	_	NOUN	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	membrane	_	NOUN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	HLA	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	DR	_	PROPN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	CD20	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Internal	_	ADJ	_	Degree=Pos	_	_	_	_
2	labeling	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	[	_	PUNCT	_	_	_	_	_	_
5	35	_	NUM	_	NumType=Card	_	_	_	_
6	S	_	NOUN	_	Number=Sing	_	_	_	_
7	]	_	PUNCT	_	_	_	_	_	_
8	methionine	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	anti-IgM	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	anti-kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	anti-lambda	_	ADJ	_	Number=Sing	_	_	_	_
18	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
19	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	striking	_	VERB	_	VerbForm=Ger	_	_	_	_
22	reduction	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	kappa	_	PROPN	_	Number=Sing	_	_	_	_
25	L	_	PROPN	_	Number=Sing	_	_	_	_
26	chain	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	presence	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	TGF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	beta	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	less	_	ADV	_	Degree=Cmp	_	_	_	_
3	pronounced	_	ADJ	_	Degree=Pos	_	_	_	_
4	reduction	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	lambda	_	PROPN	_	Number=Sing	_	_	_	_
7	L	_	PROPN	_	Number=Sing	_	_	_	_
8	chain	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	microH	_	NOUN	_	Number=Sing	_	_	_	_
11	chain	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	noted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	RNA	_	PROPN	_	Number=Sing	_	_	_	_
6	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	TGF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	varying	_	ADJ	_	VerbForm=Ger	_	_	_	_
17	time	_	NOUN	_	Number=Sing	_	_	_	_
18	intervals	_	NOUN	_	Number=Plur	_	_	_	_
19	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	significant	_	ADJ	_	Degree=Pos	_	_	_	_
22	decrease	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	steady	_	ADJ	_	Degree=Pos	_	_	_	_
25	state	_	NOUN	_	Number=Sing	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	lambda	_	NOUN	_	Number=Sing	_	_	_	_
29	L	_	PROPN	_	Number=Sing	_	_	_	_
30	chain	_	NOUN	_	Number=Sing	_	_	_	_
31	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
32	levels	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	significant	_	ADJ	_	Degree=Pos	_	_	_	_
5	decrease	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	switch	_	NOUN	_	Number=Sing	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	membrane	_	ADJ	_	Number=Sing	_	_	_	_
12	forms	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	mu	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	gamma	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	respective	_	ADJ	_	Degree=Pos	_	_	_	_
20	secreted	_	ADJ	_	Degree=Pos	_	_	_	_
21	forms	_	NOUN	_	Number=Plur	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	noted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	presence	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	TGF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	beta	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	run	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	experiments	_	NOUN	_	Number=Plur	_	_	_	_
6	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	kappa	_	PROPN	_	Number=Sing	_	_	_	_
11	L	_	PROPN	_	Number=Sing	_	_	_	_
12	chain	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TGF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	Oct	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	important	_	ADJ	_	Degree=Pos	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	Ig	_	PROPN	_	Degree=Pos	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Oct	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	both	_	CCONJ	_	_	_	_	_	_
8	Oct	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	extracts	_	NOUN	_	Number=Plur	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	treatment	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	TGF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	beta	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	important	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	B	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	Ig	_	NOUN	_	Number=Sing	_	_	_	_
24	production	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	TGF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	beta	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TGF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	decreases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	Ig	_	NOUN	_	Number=Sing	_	_	_	_
12	secretion	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	Ig	_	PROPN	_	Number=Sing	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	switch	_	NOUN	_	Number=Sing	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	membrane	_	NOUN	_	Number=Sing	_	_	_	_
27	form	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	forms	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	mu	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	gamma	_	NOUN	_	Number=Sing	_	_	_	_
36	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	TGF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibits	_	VERB	_	Number=Sing	_	_	_	_
9	Ig	_	PROPN	_	Number=Sing	_	_	_	_
10	chain	_	NOUN	_	Number=Sing	_	_	_	_
11	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	although	_	SCONJ	_	_	_	_	_	_
15	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
19	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	Oct	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	respective	_	ADJ	_	Degree=Pos	_	_	_	_
35	target	_	NOUN	_	Number=Sing	_	_	_	_
36	sequences	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001673	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Temporal	_	ADJ	_	Degree=Pos	_	_	_	_
2	control	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IgH	_	ADJ	_	Degree=Pos	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	SCONJ	_	_	_	_	_	_
8	developing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	B	_	ADJ	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	3	_	NUM	_	NumType=Card	_	_	_	_
14	'	_	PUNCT	_	_	_	_	_	_
15	locus	_	NOUN	_	Number=Sing	_	_	_	_
16	control	_	NOUN	_	Number=Sing	_	_	_	_
17	region	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	roles	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
7	3	_	NUM	_	NumType=Card	_	_	_	_
8	'	_	PUNCT	_	_	_	_	_	_
9	regions	_	NOUN	_	Number=Plur	_	_	_	_
10	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	Locus	_	PROPN	_	Number=Sing	_	_	_	_
14	Control	_	PROPN	_	Number=Sing	_	_	_	_
15	Region	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	LCR	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	allowed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	comparisons	_	NOUN	_	Number=Plur	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	made	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	between	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	regulation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	IgH	_	PROPN	_	Number=Sing	_	_	_	_
32	locus	_	NOUN	_	Number=Sing	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	other	_	ADJ	_	Degree=Pos	_	_	_	_
35	model	_	NOUN	_	Number=Sing	_	_	_	_
36	systems	_	NOUN	_	Number=Plur	_	_	_	_
37	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	governed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
42	by	_	ADP	_	_	_	_	_	_
43	LCR	_	NOUN	_	Number=Sing	_	_	_	_
44	activity	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	summarize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	importance	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IgH	_	PROPN	_	Number=Sing	_	_	_	_
9	3'	_	NOUN	_	_	_	_	_	_
10	LCR	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	putative	_	ADJ	_	Degree=Pos	_	_	_	_
14	functional	_	ADJ	_	Degree=Pos	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	IgH	_	ADJ	_	Degree=Pos	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	compare	_	VERB	_	VerbForm=Inf	_	_	_	_
22	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	5'LCR	_	ADJ	_	Number=Sing	_	_	_	_
26	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	region	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	beta-globin	_	NOUN	_	Number=Sing	_	_	_	_
32	locus	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001683	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	ERP	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	new	_	ADJ	_	Degree=Pos	_	_	_	_
5	member	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	ets	_	NOUN	_	Number=Sing	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
13	family	_	NOUN	_	Number=Sing	_	_	_	_
14	:	_	PUNCT	_	_	_	_	_	_
15	cloning	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	characterization	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	differential	_	ADJ	_	Degree=Pos	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	during	_	ADP	_	_	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
26	development	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ets	_	NOUN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	family	_	NOUN	_	Number=Sing	_	_	_	_
5	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	group	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	function	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	under	_	ADP	_	_	_	_	_	_
16	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
17	conditions	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	if	_	SCONJ	_	_	_	_	_	_
21	aberrantly	_	ADV	_	_	_	_	_	_
22	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	can	_	AUX	_	VerbForm=Fin	_	_	_	_
25	cause	_	VERB	_	VerbForm=Inf	_	_	_	_
26	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
27	transformation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	recently	_	ADV	_	_	_	_	_	_
4	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	elements	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	murine	_	NOUN	_	Number=Sing	_	_	_	_
11	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
12	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	chain	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	IgH	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	pi	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	microB	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	exhibit	_	VERB	_	Number=Sing	_	_	_	_
26	striking	_	VERB	_	VerbForm=Ger	_	_	_	_
27	similarity	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	binding	_	VERB	_	VerbForm=Inf	_	_	_	_
30	sites	_	NOUN	_	Number=Plur	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	ets	_	NOUN	_	Number=Plur	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	related	_	ADJ	_	Degree=Pos	_	_	_	_
35	proteins	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
3	ets-related	_	ADJ	_	Degree=Pos	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulators	_	NOUN	_	Number=Plur	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	either	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	pi	_	NOUN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	microB	_	NOUN	_	Number=Sing	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
23	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	PCR	_	NOUN	_	Number=Sing	_	_	_	_
27	approach	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	degenerate	_	ADJ	_	Degree=Pos	_	_	_	_
30	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
31	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
32	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	sequences	_	NOUN	_	Number=Plur	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	all	_	DET	_	_	_	_	_	_
36	members	_	NOUN	_	Number=Plur	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	ets	_	NOUN	_	Number=Sing	_	_	_	_
40	family	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	new	_	ADJ	_	Degree=Pos	_	_	_	_
9	ets-related	_	ADJ	_	Degree=Pos	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	ERP	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	ets-related	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	murine	_	NOUN	_	Number=Sing	_	_	_	_
22	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	line	_	NOUN	_	Number=Sing	_	_	_	_
25	BASC	_	NOUN	_	Number=Sing	_	_	_	_
26	6C2	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	mouse	_	NOUN	_	Number=Sing	_	_	_	_
30	lung	_	NOUN	_	Number=Sing	_	_	_	_
31	tissue	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ERP	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	region	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	high	_	ADJ	_	Degree=Pos	_	_	_	_
9	homology	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	ETS	_	NOUN	_	Number=Sing	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	domain	_	NOUN	_	Number=Sing	_	_	_	_
17	common	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	all	_	DET	_	_	_	_	_	_
20	members	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	ets	_	NOUN	_	Number=Sing	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
28	family	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Three	_	NUM	_	NumType=Card	_	_	_	_
2	additional	_	ADJ	_	Degree=Pos	_	_	_	_
3	smaller	_	ADJ	_	Degree=Cmp	_	_	_	_
4	regions	_	NOUN	_	Number=Plur	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	homology	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	ELK	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	SAP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	subgroup	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	ets	_	NOUN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	family	_	NOUN	_	Number=Sing	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	serum	_	NOUN	_	Number=Sing	_	_	_	_
30	response	_	NOUN	_	Number=Sing	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Full	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	length	_	NOUN	_	Number=Sing	_	_	_	_
4	ERP	_	NOUN	_	Number=Sing	_	_	_	_
5	expresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	only	_	ADV	_	_	_	_	_	_
7	negligible	_	ADJ	_	Degree=Pos	_	_	_	_
8	DNA	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	itself	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs|Reflex=Yes	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Removal	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	carboxy	_	NOUN	_	Number=Sing	_	_	_	_
5	terminus	_	NOUN	_	Number=Sing	_	_	_	_
6	enables	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	ERP	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	variety	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	ets	_	NOUN	_	Number=Plur	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	sites	_	NOUN	_	Number=Plur	_	_	_	_
18	including	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	E74	_	NUM	_	Number=Sing	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	IgH	_	PROPN	_	Number=Sing	_	_	_	_
25	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
26	pi	_	NOUN	_	Number=Sing	_	_	_	_
27	site	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	lck	_	NOUN	_	Number=Sing	_	_	_	_
32	promoter	_	NOUN	_	Number=Sing	_	_	_	_
33	ets	_	NOUN	_	Number=Sing	_	_	_	_
34	site	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	carboxy	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
41	negative	_	ADJ	_	Number=Sing	_	_	_	_
42	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
43	domain	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADV	_	_	_	_	_	_
2	least	_	ADV	_	Degree=Sup	_	_	_	_
3	three	_	NUM	_	NumType=Card	_	_	_	_
4	ERP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	related	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	variety	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	tissues	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	within	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lineage	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	ERP	_	PROPN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	highly	_	ADV	_	_	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	primarily	_	ADV	_	_	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	early	_	ADJ	_	Degree=Pos	_	_	_	_
17	stages	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
22	development	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	declines	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	drastically	_	ADV	_	_	_	_	_	_
28	upon	_	ADP	_	_	_	_	_	_
29	B	_	NOUN	_	Degree=Pos	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	maturation	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	correlating	_	VERB	_	VerbForm=Ger	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
38	activity	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	IgH	_	PROPN	_	Number=Sing	_	_	_	_
42	pi	_	NOUN	_	Number=Sing	_	_	_	_
43	site	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	ERP	_	PROPN	_	Number=Sing	_	_	_	_
6	might	_	AUX	_	VerbForm=Fin	_	_	_	_
7	play	_	VERB	_	VerbForm=Inf	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	development	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	IgH	_	ADJ	_	Degree=Pos	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001685	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	growth	_	NOUN	_	Number=Sing	_	_	_	_
5	hormone	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	secretion	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	translocation	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	pointed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	link	_	NOUN	_	Number=Sing	_	_	_	_
8	between	_	ADP	_	_	_	_	_	_
9	immune	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	endocrine	_	NOUN	_	Number=Sing	_	_	_	_
12	systems	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	including	_	VERB	_	VerbForm=Ger	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	function	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	GH	_	NOUN	_	Number=Sing	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	THP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	engineered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	transfer	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	constitutively	_	ADV	_	_	_	_	_	_
19	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	growth	_	NOUN	_	Number=Sing	_	_	_	_
22	hormone	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	hGH	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	depressed	_	ADJ	_	Degree=Pos	_	_	_	_
29	amounts	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	TNF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	response	_	NOUN	_	Number=Sing	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	challenge	_	NOUN	_	Number=Sing	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	LPS	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	GH	_	PROPN	_	Number=Sing	_	_	_	_
5	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	autocrine	_	ADJ	_	Degree=Pos	_	_	_	_
11	fashion	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	since	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
16	effect	_	NOUN	_	Number=Sing	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	TNF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	secretion	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
24	GH	_	NOUN	_	Number=Sing	_	_	_	_
25	production	_	NOUN	_	Number=Sing	_	_	_	_
26	could	_	AUX	_	VerbForm=Fin	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	presence	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	anti-hGH	_	PROPN	_	Degree=Pos	_	_	_	_
34	mAb	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GH	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	using	_	VERB	_	VerbForm=Ger	_	_	_	_
11	normal	_	ADJ	_	Degree=Pos	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TNF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	production	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	THP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1-hGH	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	presence	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	LPS	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	selective	_	ADJ	_	Degree=Pos	_	_	_	_
25	pathway	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	since	_	SCONJ	_	_	_	_	_	_
28	no	_	DET	_	_	_	_	_	_
29	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	TNF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	production	_	NOUN	_	Number=Sing	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	when	_	ADV	_	PronType=Int	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	cultured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	presence	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	PMA	_	PROPN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TNF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	secretion	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	LPS	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	THP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	hGH	_	NOUN	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	decrease	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	translocation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	capacity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	GH	_	PROPN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
7	LPS	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	TNF	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	without	_	SCONJ	_	_	_	_	_	_
17	altering	_	VERB	_	VerbForm=Ger	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	pathways	_	NOUN	_	Number=Plur	_	_	_	_
20	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	TNF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	production	_	NOUN	_	Number=Sing	_	_	_	_
26	may	_	AUX	_	VerbForm=Fin	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	potential	_	ADJ	_	Degree=Pos	_	_	_	_
30	relevance	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	septic	_	ADJ	_	Number=Sing	_	_	_	_
33	shock	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	since	_	SCONJ	_	_	_	_	_	_
36	GH	_	PROPN	_	Number=Sing	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	available	_	ADJ	_	Degree=Pos	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
41	use	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001691	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	IL3	_	X	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	primary	_	ADJ	_	Degree=Pos	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Role	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	AP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	octamer	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	control	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IL3	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
8	basis	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
13	3	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	IL3	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	primary	_	ADJ	_	Degree=Pos	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	following	_	VERB	_	VerbForm=Ger	_	_	_	_
25	CD3	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	CD2	_	PROPN	_	Number=Sing	_	_	_	_
28	receptor	_	NOUN	_	Number=Sing	_	_	_	_
29	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
34	plus	_	CCONJ	_	_	_	_	_	_
35	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
36	12	_	NUM	_	NumType=Card	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	myristate	_	NOUN	_	Number=Sing	_	_	_	_
39	13	_	NUM	_	NumType=Card	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	acetate	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	reporter	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	assays	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	specifically	_	ADV	_	_	_	_	_	_
8	designed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	primary	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	conjunction	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	gel	_	NOUN	_	Number=Sing	_	_	_	_
17	retardation	_	NOUN	_	Number=Sing	_	_	_	_
18	assays	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	Western	_	ADJ	_	Degree=Pos	_	_	_	_
21	blot	_	NOUN	_	Number=Sing	_	_	_	_
22	analyses	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	UV	_	PROPN	_	Number=Sing	_	_	_	_
25	cross	_	VERB	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	linking	_	VERB	_	Number=Sing	_	_	_	_
28	studies	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
31	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	that	_	SCONJ	_	_	_	_	_	_
33	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	c-Fos	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	octamer	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	binding	_	VERB	_	Number=Sing	_	_	_	_
41	proteins	_	NOUN	_	Number=Plur	_	_	_	_
42	play	_	VERB	_	VerbForm=Inf	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	major	_	ADJ	_	Degree=Pos	_	_	_	_
45	role	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
48	activation	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	IL3	_	PROPN	_	Number=Sing	_	_	_	_
52	gene	_	NOUN	_	Number=Sing	_	_	_	_
53	via	_	ADP	_	_	_	_	_	_
54	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
55	interaction	_	NOUN	_	Number=Sing	_	_	_	_
56	with	_	ADP	_	_	_	_	_	_
57	two	_	NUM	_	NumType=Card	_	_	_	_
58	specific	_	ADJ	_	Degree=Pos	_	_	_	_
59	regions	_	NOUN	_	Number=Plur	_	_	_	_
60	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
61	within	_	ADP	_	_	_	_	_	_
62	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
63	IL3	_	PROPN	_	Number=Sing	_	_	_	_
64	5	_	NUM	_	NumType=Card	_	_	_	_
65	'-	_	PUNCT	_	_	_	_	_	_
66	flanking	_	NOUN	_	Number=Sing	_	_	_	_
67	sequence	_	NOUN	_	Number=Sing	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	between	_	ADP	_	_	_	_	_	_
6	bases	_	NOUN	_	Number=Plur	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	107	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	-	_	SYM	_	_	_	_	_	_
11	59	_	NUM	_	NumType=Card	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL3	_	PROPN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	putative	_	ADJ	_	Degree=Pos	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	motifs	_	NOUN	_	Number=Plur	_	_	_	_
25	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	basal	_	ADJ	_	Degree=Pos	_	_	_	_
29	level	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	IL3	_	PROPN	_	Number=Sing	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	CD2	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
11	plus	_	CCONJ	_	_	_	_	_	_
12	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
13	12	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	myristate	_	NOUN	_	Number=Sing	_	_	_	_
16	13	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	acetate	_	ADJ	_	Degree=Pos	_	_	_	_
19	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
20	augment	_	NOUN	_	Number=Sing	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	IL3	_	NOUN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	through	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	same	_	ADJ	_	Degree=Pos	_	_	_	_
29	cis	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	trans	_	NOUN	_	Number=Plur	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
35	signals	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	should	_	AUX	_	VerbForm=Fin	_	_	_	_
4	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	better	_	ADJ	_	Degree=Cmp	_	_	_	_
8	understanding	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IL3	_	NOUN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001706	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tcf	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1-	_	NUM	_	_	_	_	_	_
4	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	:	_	PUNCT	_	_	_	_	_	_
10	differential	_	ADJ	_	Degree=Pos	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	glycogen	_	NOUN	_	Number=Sing	_	_	_	_
14	synthase	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	3	_	NUM	_	NumType=Card	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Beta	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	catenin	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	vertebrate	_	ADJ	_	Degree=Pos	_	_	_	_
7	homolog	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	Drosophila	_	PROPN	_	Number=Sing	_	_	_	_
11	segment	_	NOUN	_	Number=Sing	_	_	_	_
12	polarity	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	Armadillo	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	roles	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	both	_	DET	_	_	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	transduction	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	Wnt	_	NOUN	_	Number=Sing	_	_	_	_
29	signaling	_	NOUN	_	Number=Sing	_	_	_	_
30	cascade	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	members	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	Lef	_	PROPN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	Tcf	_	PROPN	_	Number=Sing	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	family	_	NOUN	_	Number=Sing	_	_	_	_
12	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	partners	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	catenin	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	explaining	_	VERB	_	VerbForm=Ger	_	_	_	_
24	how	_	ADV	_	PronType=Int	_	_	_	_
25	beta	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	catenin	_	NOUN	_	Number=Sing	_	_	_	_
28	alters	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	Tcf	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	becomes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	transcriptionally	_	ADV	_	_	_	_	_	_
15	active	_	ADJ	_	Degree=Pos	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	interaction	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	beta-catenin	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	Wnt	_	NOUN	_	Number=Sing	_	_	_	_
25	signal	_	NOUN	_	Number=Sing	_	_	_	_
26	transduction	_	NOUN	_	Number=Sing	_	_	_	_
27	pathway	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	operational	_	ADJ	_	Degree=Pos	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	T	_	PROPN	_	Number=Sing	_	_	_	_
32	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	as	_	ADV	_	_	_	_	_	_
34	well	_	ADV	_	Degree=Pos	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	although	_	SCONJ	_	_	_	_	_	_
4	Wnt	_	NOUN	_	Number=Sing	_	_	_	_
5	signals	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	negative	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	glycogen	_	NOUN	_	Number=Sing	_	_	_	_
19	synthase	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	3beta	_	PROPN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	GSK	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	3beta	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	levels	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	beta	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	catenin	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
39	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	no	_	DET	_	_	_	_	_	_
41	evidence	_	NOUN	_	Number=Sing	_	_	_	_
42	for	_	ADP	_	_	_	_	_	_
43	involvement	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	GSK	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	3beta	_	PROPN	_	Number=Sing	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	Tcf	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
52	transcription	_	NOUN	_	Number=Sing	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	T	_	PROPN	_	Number=Sing	_	_	_	_
55	cells	_	NOUN	_	Number=Plur	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	That	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
6	negative	_	ADJ	_	Degree=Pos	_	_	_	_
7	GSK	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	3beta	_	NOUN	_	Number=Sing	_	_	_	_
10	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	specifically	_	ADV	_	_	_	_	_	_
13	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	Tcf	_	PROPN	_	Number=Sing	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	lithium	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	that	_	PRON	_	_	_	_	_	_
24	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
25	GSK	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	3beta	_	PROPN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	also	_	ADV	_	_	_	_	_	_
30	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	not	_	PART	_	_	_	_	_	_
32	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
33	Tcf	_	PROPN	_	Number=Sing	_	_	_	_
34	reporter	_	NOUN	_	Number=Sing	_	_	_	_
35	genes	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	GSK	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	3beta	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	insufficient	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	Tcf	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	C57MG	_	PROPN	_	Number=Sing	_	_	_	_
6	fibroblast	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	lithium	_	NOUN	_	Number=Sing	_	_	_	_
10	inactivates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	GSK	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	3beta	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	Tcf	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
5	demonstration	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	lithium	_	NOUN	_	Number=Sing	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Tcf	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	points	_	NOUN	_	Number=Plur	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	difference	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	regulation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	Wnt	_	NOUN	_	Number=Sing	_	_	_	_
27	signaling	_	VERB	_	Number=Sing	_	_	_	_
28	between	_	ADP	_	_	_	_	_	_
29	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001712	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
11	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	chain	_	NOUN	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	conjunction	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	OTF2	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	tissue	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	MOPC	_	PROPN	_	Number=Sing	_	_	_	_
9	141	_	NUM	_	NumType=Card	_	_	_	_
10	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
11	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	chain	_	NOUN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	SCONJ	_	_	_	_	_	_
18	using	_	VERB	_	VerbForm=Ger	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	vitro	_	NOUN	_	Number=Sing	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	B-cell	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	octamer	_	NOUN	_	Number=Sing	_	_	_	_
13	element	_	NOUN	_	Number=Sing	_	_	_	_
14	5'-	_	NOUN	_	Number=Sing	_	_	_	_
15	ATGCAAAG	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	3	_	NUM	_	NumType=Card	_	_	_	_
18	'	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
24	region	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	promoters	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	all	_	DET	_	_	_	_	_	_
34	other	_	ADJ	_	Degree=Pos	_	_	_	_
35	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
36	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	light	_	ADJ	_	Degree=Pos	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	chain	_	NOUN	_	Number=Sing	_	_	_	_
42	genes	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	interaction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	octamer	_	NOUN	_	Number=Sing	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	OTF1	_	NOUN	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	OTF2	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	MOPC	_	NOUN	_	Number=Sing	_	_	_	_
19	141	_	NUM	_	NumType=Card	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	SCONJ	_	_	_	_	_	_
24	using	_	VERB	_	VerbForm=Ger	_	_	_	_
25	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
26	mobility	_	NOUN	_	Number=Sing	_	_	_	_
27	shift	_	NOUN	_	Number=Sing	_	_	_	_
28	assays	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	DNase	_	PROPN	_	Number=Sing	_	_	_	_
31	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
32	footprinting	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	OTF1	_	NOUN	_	Number=Sing	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	OTF1	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	OTF2	_	NOUN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	B	_	ADJ	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	bound	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	identical	_	ADJ	_	Degree=Pos	_	_	_	_
16	sequences	_	NOUN	_	Number=Plur	_	_	_	_
17	within	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	chain	_	NOUN	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	OTF	_	NOUN	_	Number=Sing	_	_	_	_
3	interactions	_	NOUN	_	Number=Plur	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	extended	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	over	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	heptamer	_	NOUN	_	Number=Sing	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	5'-	_	NOUN	_	Number=Sing	_	_	_	_
12	CTCAGGA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	3	_	NUM	_	NumType=Card	_	_	_	_
15	'	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
19	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	likely	_	ADJ	_	Degree=Pos	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	factors	_	NOUN	_	Number=Plur	_	_	_	_
28	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
30	between	_	ADP	_	_	_	_	_	_
31	octamer	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	heptamer	_	ADJ	_	Number=Sing	_	_	_	_
34	sites	_	NOUN	_	Number=Plur	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
37	promoter	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	N	_	NOUN	_	Number=Sing	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	sequence	_	NOUN	_	Number=Sing	_	_	_	_
20	5'-	_	NOUN	_	_	_	_	_	_
21	GGAACCTCCCCC	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	3	_	NUM	_	NumType=Card	_	_	_	_
24	'	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	N	_	NOUN	_	Number=Sing	_	_	_	_
3	element	_	NOUN	_	Number=Sing	_	_	_	_
4	could	_	AUX	_	VerbForm=Fin	_	_	_	_
5	independently	_	ADV	_	_	_	_	_	_
6	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	low	_	ADJ	_	Degree=Pos	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	HeLa	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	extracts	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	conjunction	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	octamer	_	NOUN	_	Number=Sing	_	_	_	_
29	element	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
32	can	_	AUX	_	VerbForm=Fin	_	_	_	_
33	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
34	high	_	ADJ	_	Degree=Pos	_	_	_	_
35	levels	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	B	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	extracts	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	N	_	NOUN	_	Number=Sing	_	_	_	_
3	element	_	NOUN	_	Number=Sing	_	_	_	_
4	bound	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	NTF	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	distribution	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	NTF	_	PROPN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	any	_	DET	_	_	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	previously	_	ADV	_	_	_	_	_	_
29	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	that	_	PRON	_	PronType=Rel	_	_	_	_
32	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	similar	_	ADJ	_	Degree=Pos	_	_	_	_
35	sequences	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	NTF	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	OTF2	_	NOUN	_	Number=Sing	_	_	_	_
12	interactions	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	cognate	_	ADJ	_	Degree=Pos	_	_	_	_
18	DNA	_	NOUN	_	Number=Sing	_	_	_	_
19	elements	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	possibly	_	ADV	_	_	_	_	_	_
22	at	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	level	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	may	_	AUX	_	VerbForm=Fin	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	critical	_	ADJ	_	Degree=Pos	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	specific	_	ADJ	_	Degree=Pos	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	that	_	SCONJ	_	_	_	_	_	_
41	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
42	interactions	_	NOUN	_	Number=Plur	_	_	_	_
43	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
44	additional	_	ADJ	_	Degree=Pos	_	_	_	_
45	pathways	_	NOUN	_	Number=Plur	_	_	_	_
46	for	_	SCONJ	_	_	_	_	_	_
47	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
48	gene	_	NOUN	_	Number=Sing	_	_	_	_
49	expression	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001713	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Fibroblast	_	ADJ	_	Degree=Pos	_	_	_	_
2	growth	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	FGF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	production	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	translocation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	FGF	_	PROPN	_	Number=Sing	_	_	_	_
25	receptor	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
28	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
29	T	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Fibroblast	_	ADJ	_	Degree=Pos	_	_	_	_
2	growth	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	FGFs	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	heparin	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	embryogenesis	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	angiogenesis	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	wound	_	NOUN	_	Number=Sing	_	_	_	_
20	healing	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	FGF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	abundantly	_	ADV	_	_	_	_	_	_
6	expressed	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	synovium	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	rheumatoid	_	ADJ	_	Number=Sing	_	_	_	_
12	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	in	_	SCONJ	_	_	_	_	_	_
15	rejecting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	allografts	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
21	immune	_	ADJ	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
24	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	frequency	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	FGF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1-	_	NUM	_	_	_	_	_	_
7	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
15	blood	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
18	disorders	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	high	_	ADJ	_	Degree=Pos	_	_	_	_
23	percentage	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	infiltrating	_	VERB	_	VerbForm=Ger	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	rheumatoid	_	ADJ	_	Number=Sing	_	_	_	_
30	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
31	synovium	_	NOUN	_	Number=Sing	_	_	_	_
32	express	_	ADJ	_	Number=Sing	_	_	_	_
33	receptors	_	NOUN	_	Number=Plur	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	FGF	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	action	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	FGF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	studies	_	NOUN	_	Number=Plur	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	initiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	signaling	_	NOUN	_	Number=Sing	_	_	_	_
24	isoform	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	FGF	_	NOUN	_	Number=Sing	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	FGF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
16	signal	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	augments	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	TCR	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	production	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Analogous	_	ADJ	_	Degree=Pos	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	via	_	ADP	_	_	_	_	_	_
5	CD28	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	Rel	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	family	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	other	_	ADJ	_	Degree=Pos	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
34	proteins	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	FGF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	alone	_	ADV	_	_	_	_	_	_
5	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	modest	_	ADJ	_	Degree=Pos	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	translocation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	translocation	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	combination	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	anti-CD3	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	FGF	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	complex	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transcriptionally	_	ADV	_	_	_	_	_	_
11	active	_	ADJ	_	Degree=Pos	_	_	_	_
12	p65	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	RelA	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	p50	_	NUM	_	NumType=Card	_	_	_	_
18	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	results	_	NOUN	_	Number=Plur	_	_	_	_
21	primarily	_	ADV	_	_	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	degradation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
33	that	_	PRON	_	PronType=Rel	_	_	_	_
34	sequesters	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	Rel	_	NOUN	_	Number=Sing	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	show	_	VERB	_	VerbForm=Inf	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	connection	_	NOUN	_	Number=Sing	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	FGF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	signaling	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	outside	_	ADP	_	_	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
23	development	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	signaling	_	NOUN	_	Number=Sing	_	_	_	_
3	events	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	DET	_	PronType=Rel	_	_	_	_
5	link	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	FGF	_	PROPN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	engagement	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	probably	_	ADV	_	_	_	_	_	_
20	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	CD28	_	PROPN	_	Number=Sing	_	_	_	_
24	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
25	pathway	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	since	_	SCONJ	_	_	_	_	_	_
28	FGF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	Rel	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
36	binding	_	VERB	_	Number=Sing	_	_	_	_
37	proteins	_	NOUN	_	Number=Plur	_	_	_	_
38	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	not	_	PART	_	_	_	_	_	_
40	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
41	significant	_	ADJ	_	Degree=Pos	_	_	_	_
42	levels	_	NOUN	_	Number=Plur	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	c	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	Rel	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
49	not	_	PART	_	_	_	_	_	_
50	identical	_	ADJ	_	Degree=Pos	_	_	_	_
51	with	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	CD28	_	PROPN	_	Number=Sing	_	_	_	_
54	response	_	NOUN	_	Number=Sing	_	_	_	_
55	complex	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001718	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	blood	_	NOUN	_	Number=Sing	_	_	_	_
13	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	acts	_	VERB	_	Number=Plur	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	blood	_	NOUN	_	Number=Sing	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	by	_	SCONJ	_	_	_	_	_	_
18	enhancing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	binding	_	VERB	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	_	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	consensus	_	NOUN	_	Number=Sing	_	_	_	_
32	sequence	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	5	_	NUM	_	NumType=Card	_	_	_	_
36	'	_	PUNCT	_	_	_	_	_	_
37	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
38	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
39	region	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	2	_	NUM	_	NumType=Card	_	_	_	_
45	receptor	_	NOUN	_	Number=Sing	_	_	_	_
46	alpha	_	PROPN	_	Number=Sing	_	_	_	_
47	chain	_	NOUN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	p55	_	NOUN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Similarly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	line	_	NOUN	_	Number=Sing	_	_	_	_
17	U	_	PROPN	_	_	_	_	_	_
18	937	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	not	_	ADV	_	_	_	_	_	_
22	in	_	SCONJ	_	_	_	_	_	_
23	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
5	within	_	ADP	_	_	_	_	_	_
6	15	_	NUM	_	NumType=Card	_	_	_	_
7	min	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	peaks	_	NOUN	_	Number=Plur	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	h	_	NOUN	_	Number=Sing	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	exposure	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_
19	Enhanced	_	VERB	_	Number=Sing	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	SCONJ	_	Number=Sing	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	followed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	functional	_	ADJ	_	Degree=Pos	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	chain	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	PROPN	_	Number=Sing	_	_	_	_
27	B	_	PROPN	_	Number=Sing	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	that	_	SCONJ	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappa	_	NOUN	_	Number=Sing	_	_	_	_
39	B	_	NOUN	_	Number=Sing	_	_	_	_
40	consensus	_	NOUN	_	Number=Sing	_	_	_	_
41	sequence	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	291	_	NUM	_	NumType=Card	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	-	_	SYM	_	_	_	_	_	_
47	245	_	NUM	_	NumType=Card	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	IL	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	2	_	NUM	_	NumType=Card	_	_	_	_
54	receptor	_	NOUN	_	Number=Sing	_	_	_	_
55	alpha	_	NOUN	_	Number=Sing	_	_	_	_
56	chain	_	NOUN	_	Number=Sing	_	_	_	_
57	gene	_	NOUN	_	Number=Sing	_	_	_	_
58	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
59	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	capable	_	ADJ	_	Degree=Pos	_	_	_	_
9	of	_	SCONJ	_	_	_	_	_	_
10	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	transcript	_	NOUN	_	Number=Sing	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	p50	_	NUM	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	coding	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	p50	_	NUM	_	Number=Sing	_	_	_	_
21	subunit	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	whereas	_	SCONJ	_	_	_	_	_	_
32	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
33	levels	_	NOUN	_	Number=Plur	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	p65	_	NUM	_	Number=Sing	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kappa	_	NOUN	_	Number=Sing	_	_	_	_
40	B	_	PROPN	_	Number=Sing	_	_	_	_
41	gene	_	NOUN	_	Number=Sing	_	_	_	_
42	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	unchanged	_	ADJ	_	Degree=Pos	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001723	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
3	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	element	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	nuclease	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	pol	_	NOUN	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
20	virus	_	NOUN	_	Number=Sing	_	_	_	_
21	type	_	NOUN	_	Number=Sing	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	chromatin	_	ADJ	_	Number=Sing	_	_	_	_
5	organization	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	integrated	_	ADJ	_	Degree=Pos	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
11	virus	_	NOUN	_	Number=Sing	_	_	_	_
12	type	_	NOUN	_	Number=Sing	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	genome	_	NOUN	_	Number=Sing	_	_	_	_
20	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	previously	_	ADV	_	_	_	_	_	_
22	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	major	_	ADJ	_	Degree=Pos	_	_	_	_
25	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
26	DNase	_	NOUN	_	Number=Sing	_	_	_	_
27	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
30	site	_	NOUN	_	Number=Sing	_	_	_	_
31	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	pol	_	NOUN	_	Number=Sing	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	E.	_	PROPN	_	Number=Sing	_	_	_	_
38	Verdin	_	PROPN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	J.	_	PROPN	_	Number=Sing	_	_	_	_
41	Virol.	_	PROPN	_	Number=Sing	_	_	_	_
42	65:6790-6799	_	NUM	_	NumType=Card	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	1991	_	NUM	_	NumType=Card	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	report	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	high	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	resolution	_	NOUN	_	Number=Sing	_	_	_	_
9	mapping	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	DNase	_	NOUN	_	Number=Sing	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	micrococcal	_	ADJ	_	Degree=Pos	_	_	_	_
18	nuclease	_	NOUN	_	Number=Sing	_	_	_	_
19	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	nucleosome	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	free	_	ADJ	_	Degree=Pos	_	_	_	_
24	region	_	NOUN	_	Number=Sing	_	_	_	_
25	centered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	around	_	ADP	_	_	_	_	_	_
27	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	nt	_	PART	_	_	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	4490	_	NUM	_	NumType=Card	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	4766	_	NUM	_	NumType=Card	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	500	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	bp	_	NOUN	_	Number=Sing	_	_	_	_
5	fragment	_	NOUN	_	Number=Sing	_	_	_	_
6	encompassing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	nt	_	CCONJ	_	_	_	_	_	_
12	4481	_	NUM	_	NumType=Card	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	4982	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	exhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	enhancing	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	two	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	threefold	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	when	_	ADV	_	PronType=Int	_	_	_	_
28	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
33	natural	_	ADJ	_	Degree=Pos	_	_	_	_
34	position	_	NOUN	_	Number=Sing	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	respect	_	NOUN	_	Number=Sing	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	HIV	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	after	_	ADP	_	_	_	_	_	_
44	transient	_	ADJ	_	Degree=Pos	_	_	_	_
45	transfection	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	U937	_	PROPN	_	Number=Sing	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	CEM	_	PROPN	_	Number=Sing	_	_	_	_
50	cells	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	vitro	_	NOUN	_	Number=Sing	_	_	_	_
4	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	gel	_	NOUN	_	Number=Sing	_	_	_	_
7	shift	_	NOUN	_	Number=Sing	_	_	_	_
8	assays	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	four	_	NUM	_	NumType=Card	_	_	_	_
14	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
15	binding	_	NOUN	_	VerbForm=Ger	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	within	_	ADP	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	positive	_	ADJ	_	Degree=Pos	_	_	_	_
23	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	element	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Site	_	NOUN	_	Number=Sing	_	_	_	_
2	B	_	PROPN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	nt	_	PART	_	_	_	_	_	_
5	4519	_	NUM	_	NumType=Card	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	4545	_	NUM	_	NumType=Card	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	specifically	_	ADV	_	_	_	_	_	_
10	bound	_	VERB	_	Degree=Pos	_	_	_	_
11	four	_	NUM	_	NumType=Card	_	_	_	_
12	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	complexes	_	NOUN	_	Number=Plur	_	_	_	_
16	:	_	PUNCT	_	_	_	_	_	_

1	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	B-cell	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	B-cell	_	ADJ	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	Spi	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	most	_	ADJ	_	Degree=Sup	_	_	_	_
3	HIV	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	isolates	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	PU	_	NOUN	_	Number=Sing	_	_	_	_
11	box	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	conserved	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	replaced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	related	_	ADJ	_	Degree=Pos	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	Ets1	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Factors	_	NOUN	_	Number=Plur	_	_	_	_
2	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	site	_	NOUN	_	Number=Sing	_	_	_	_
5	C	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	nt	_	CCONJ	_	_	_	_	_	_
8	4681	_	NUM	_	NumType=Card	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	4701	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	DNA	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	specificity	_	NOUN	_	Number=Sing	_	_	_	_
18	similar	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	ADJ	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	except	_	ADP	_	_	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	Spi-1	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	GC	_	NOUN	_	Number=Sing	_	_	_	_
3	box	_	NOUN	_	Number=Sing	_	_	_	_
4	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	nt	_	CCONJ	_	_	_	_	_	_
14	4623	_	NUM	_	NumType=Card	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	4631	_	NUM	_	NumType=Card	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Site	_	NOUN	_	Number=Sing	_	_	_	_
2	D	_	PROPN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	nt	_	PART	_	_	_	_	_	_
5	4816	_	NUM	_	NumType=Card	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	4851	_	NUM	_	NumType=Card	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	specifically	_	ADV	_	_	_	_	_	_
10	bound	_	VERB	_	Degree=Pos	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	ubiquitously	_	ADV	_	_	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	nuclease	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	pol	_	NOUN	_	Degree=Pos	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	may	_	AUX	_	VerbForm=Fin	_	_	_	_
29	be	_	AUX	_	VerbForm=Inf	_	_	_	_
30	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	complex	_	ADJ	_	Degree=Pos	_	_	_	_
34	interplay	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	cis	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
39	elements	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001725	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	surface	_	NOUN	_	Number=Sing	_	_	_	_
6	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
7	molecules	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
17	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
18	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	role	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	PROPN	_	Number=Sing	_	_	_	_
29	B.	_	PROPN	_	Number=Sing	_	_	_	_
30	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
31	studies	_	NOUN	_	Number=Plur	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
34	laboratory	_	NOUN	_	Number=Sing	_	_	_	_
35	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	indicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	that	_	SCONJ	_	_	_	_	_	_
38	protein	_	NOUN	_	Number=Sing	_	_	_	_
39	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
40	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	PTPase	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
45	can	_	AUX	_	VerbForm=Fin	_	_	_	_
46	down	_	ADV	_	_	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	tumor	_	NOUN	_	Number=Sing	_	_	_	_
51	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
52	factor	_	NOUN	_	Number=Sing	_	_	_	_
53	(	_	PUNCT	_	_	_	_	_	_
54	TNF	_	PROPN	_	Number=Sing	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
58	activation	_	NOUN	_	Number=Sing	_	_	_	_
59	of	_	ADP	_	_	_	_	_	_
60	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
61	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
62	transcription	_	NOUN	_	Number=Sing	_	_	_	_
63	factor	_	NOUN	_	Number=Sing	_	_	_	_
64	NF	_	PROPN	_	Number=Sing	_	_	_	_
65	-	_	PUNCT	_	_	_	_	_	_
66	kappa	_	NOUN	_	Number=Sing	_	_	_	_
67	B	_	NOUN	_	Number=Sing	_	_	_	_
68	in	_	ADP	_	_	_	_	_	_
69	ML	_	PROPN	_	Number=Sing	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	1a	_	PROPN	_	Number=Sing	_	_	_	_
72	,	_	PUNCT	_	_	_	_	_	_
73	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
74	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
75	cell	_	NOUN	_	Number=Sing	_	_	_	_
76	line	_	NOUN	_	Number=Sing	_	_	_	_
77	(	_	PUNCT	_	_	_	_	_	_
78	Singh	_	PROPN	_	Number=Sing	_	_	_	_
79	and	_	CCONJ	_	_	_	_	_	_
80	Aggarwal	_	PROPN	_	Number=Sing	_	_	_	_
81	,	_	PUNCT	_	_	_	_	_	_
82	J.	_	PROPN	_	Number=Sing	_	_	_	_
83	Biol	_	PROPN	_	Number=Sing	_	_	_	_
84	.	_	PUNCT	_	_	_	_	_	_

1	Chem.	_	PROPN	_	Number=Sing	_	_	_	_
2	1995	_	NUM	_	NumType=Card	_	_	_	_
3	:	_	PUNCT	_	_	_	_	_	_
4	270	_	NUM	_	NumType=Card	_	_	_	_
5	:	_	PUNCT	_	_	_	_	_	_
6	10631	_	NUM	_	NumType=Card	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	TNF	_	PROPN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	one	_	NUM	_	NumType=Card	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	major	_	ADJ	_	Degree=Pos	_	_	_	_
8	inducers	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	various	_	ADJ	_	Degree=Pos	_	_	_	_
11	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
12	molecules	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	require	_	VERB	_	VerbForm=Inf	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	PROPN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
33	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	effect	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	PTPase	_	NOUN	_	Number=Sing	_	_	_	_
38	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
39	on	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	TNF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
44	induction	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
47	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
48	molecule	_	NOUN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	1	_	NUM	_	NumType=Card	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
56	cell	_	NOUN	_	Number=Sing	_	_	_	_
57	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
58	molecule	_	NOUN	_	Number=Sing	_	_	_	_
59	(	_	PUNCT	_	_	_	_	_	_
60	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
61	)	_	PUNCT	_	_	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	1	_	NUM	_	NumType=Card	_	_	_	_
64	and	_	CCONJ	_	_	_	_	_	_
65	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
66	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
67	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
68	molecule	_	NOUN	_	Number=Sing	_	_	_	_
69	(	_	PUNCT	_	_	_	_	_	_
70	ELAM	_	PROPN	_	Number=Sing	_	_	_	_
71	)	_	PUNCT	_	_	_	_	_	_
72	-	_	PUNCT	_	_	_	_	_	_
73	1	_	X	_	NumType=Card	_	_	_	_
74	.	_	PUNCT	_	_	_	_	_	_
75	Like	_	ADP	_	_	_	_	_	_
76	ML	_	NOUN	_	Number=Sing	_	_	_	_
77	-	_	PUNCT	_	_	_	_	_	_
78	1a	_	NOUN	_	Number=Sing	_	_	_	_
79	,	_	PUNCT	_	_	_	_	_	_
80	human	_	ADJ	_	Degree=Pos	_	_	_	_
81	dermal	_	ADJ	_	Number=Sing	_	_	_	_
82	microvessel	_	NOUN	_	Number=Sing	_	_	_	_
83	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
84	cells	_	NOUN	_	Number=Plur	_	_	_	_
85	(	_	PUNCT	_	_	_	_	_	_
86	MVEC	_	NOUN	_	Number=Sing	_	_	_	_
87	)	_	PUNCT	_	_	_	_	_	_
88	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
89	with	_	ADP	_	_	_	_	_	_
90	TNF	_	PROPN	_	Number=Sing	_	_	_	_
91	rapidly	_	ADV	_	_	_	_	_	_
92	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
93	(	_	PUNCT	_	_	_	_	_	_
94	within	_	ADP	_	_	_	_	_	_
95	30	_	NUM	_	NumType=Card	_	_	_	_
96	min	_	NOUN	_	Number=Plur	_	_	_	_
97	)	_	PUNCT	_	_	_	_	_	_
98	NF	_	PROPN	_	Number=Sing	_	_	_	_
99	-	_	PUNCT	_	_	_	_	_	_
100	kappa	_	NOUN	_	Number=Sing	_	_	_	_
101	B	_	NOUN	_	Number=Sing	_	_	_	_
102	;	_	PUNCT	_	_	_	_	_	_
103	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
104	effect	_	NOUN	_	Number=Sing	_	_	_	_
105	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
106	completely	_	ADV	_	_	_	_	_	_
107	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
108	by	_	ADP	_	_	_	_	_	_
109	co	_	NUM	_	Number=Sing	_	_	_	_
110	-	_	PUNCT	_	_	_	_	_	_
111	treatment	_	NOUN	_	Number=Sing	_	_	_	_
112	with	_	ADP	_	_	_	_	_	_
113	phenylarsine	_	PROPN	_	Number=Sing	_	_	_	_
114	oxide	_	NOUN	_	Number=Sing	_	_	_	_
115	(	_	PUNCT	_	_	_	_	_	_
116	PAO	_	NOUN	_	Number=Sing	_	_	_	_
117	)	_	PUNCT	_	_	_	_	_	_
118	,	_	PUNCT	_	_	_	_	_	_
119	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
120	specific	_	ADJ	_	Degree=Pos	_	_	_	_
121	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
122	of	_	ADP	_	_	_	_	_	_
123	PTPase	_	NOUN	_	Number=Sing	_	_	_	_
124	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	ELAM	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	TNF	_	PROPN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	MVEC	_	PROPN	_	Number=Sing	_	_	_	_
20	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	within	_	ADP	_	_	_	_	_	_
22	6	_	NUM	_	NumType=Card	_	_	_	_
23	h	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	also	_	ADV	_	_	_	_	_	_
27	completely	_	ADV	_	_	_	_	_	_
28	down	_	ADV	_	_	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	PAO	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	dose	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
38	manner	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	PAO	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	effective	_	ADJ	_	Degree=Pos	_	_	_	_
7	even	_	ADV	_	_	_	_	_	_
8	when	_	ADV	_	PronType=Int	_	_	_	_
9	added	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	h	_	NOUN	_	Number=Sing	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	TNF	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
18	mode	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	action	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
23	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Besides	_	ADP	_	_	_	_	_	_
2	PAO	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	other	_	ADJ	_	Degree=Pos	_	_	_	_
5	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	PTPase	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	including	_	VERB	_	VerbForm=Ger	_	_	_	_
10	pervanadate	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	diamide	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	NF	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	induction	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	all	_	DET	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	three	_	NUM	_	NumType=Card	_	_	_	_
30	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
31	proteins	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	attachment	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	MVEC	_	PROPN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	PTPase	_	NOUN	_	Number=Sing	_	_	_	_
18	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	overall	_	ADV	_	_	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
6	results	_	NOUN	_	Number=Plur	_	_	_	_
7	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	PTPase	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	involved	_	ADJ	_	Degree=Pos	_	_	_	_
13	either	_	CCONJ	_	_	_	_	_	_
14	directly	_	ADV	_	_	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	indirectly	_	ADV	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	pathway	_	NOUN	_	Number=Sing	_	_	_	_
20	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	induction	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
28	molecules	_	NOUN	_	Number=Plur	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	TNF	_	PROPN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	ADP	_	_	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	PTPase	_	NOUN	_	Number=Sing	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	novel	_	NOUN	_	Number=Sing	_	_	_	_
14	target	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	drug	_	NOUN	_	Number=Sing	_	_	_	_
17	development	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	atherogenesis	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	tumor	_	NOUN	_	Number=Sing	_	_	_	_
27	metastasis	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001730	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	AP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	CD28	_	PROPN	_	Number=Sing	_	_	_	_
12	signalling	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Co-	_	X	_	_	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	T-lymphocytes	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	TcR	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	occupancy	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	CD28	_	NOUN	_	Number=Sing	_	_	_	_
17	surface	_	NOUN	_	Number=Sing	_	_	_	_
18	molecule	_	NOUN	_	Number=Sing	_	_	_	_
19	results	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	IL	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	production	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	increase	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	CD28	_	PROPN	_	Number=Sing	_	_	_	_
12	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	like	_	ADP	_	Degree=Pos	_	_	_	_
18	sequence	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	5'-	_	ADJ	_	Number=Sing	_	_	_	_
22	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	region	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	CD28	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
35	element	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	agonistic	_	ADJ	_	Degree=Pos	_	_	_	_
6	anti-CD28	_	ADJ	_	Degree=Pos	_	_	_	_
7	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	conjunction	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
12	12	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	myristate	_	NOUN	_	Number=Sing	_	_	_	_
15	13	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	acetate	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	PMA	_	PROPN	_	Number=Sing	_	_	_	_
20	)-	_	PUNCT	_	_	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	TcR	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	signals	_	NOUN	_	Number=Plur	_	_	_	_
26	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappa	_	PROPN	_	Number=Sing	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CD28	_	PROPN	_	Number=Sing	_	_	_	_
6	engagement	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	however	_	ADV	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	opposite	_	ADJ	_	Degree=Pos	_	_	_	_
12	effects	_	NOUN	_	Number=Plur	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	AP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_
21	Whereas	_	SCONJ	_	_	_	_	_	_
22	anti-CD28	_	PROPN	_	NumType=Card	_	_	_	_
23	together	_	ADV	_	_	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	PMA	_	PROPN	_	Number=Sing	_	_	_	_
26	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	DNA	_	PROPN	_	Number=Sing	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	trans	_	NOUN	_	Number=Plur	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	activity	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappa	_	PROPN	_	Number=Sing	_	_	_	_
39	B	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	PMA	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	activation	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	AP	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	1	_	NUM	_	NumType=Card	_	_	_	_
49	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
50	significantly	_	ADV	_	_	_	_	_	_
51	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	exerted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	anti-CD28	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	level	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	DNA	_	PROPN	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	as	_	ADV	_	_	_	_	_	_
16	well	_	ADV	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	functional	_	ADJ	_	Degree=Pos	_	_	_	_
20	reporter	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	assays	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	independently	_	ADV	_	_	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	perform	_	VERB	_	VerbForm=Inf	_	_	_	_
15	different	_	ADJ	_	Degree=Pos	_	_	_	_
16	functions	_	NOUN	_	Number=Plur	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001731	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Integrin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	VERB	_	Degree=Pos	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	cytokine	_	VERB	_	Number=Sing	_	_	_	_
8	message	_	NOUN	_	Number=Sing	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	possible	_	ADJ	_	Degree=Pos	_	_	_	_
3	signaling	_	NOUN	_	Degree=Pos	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Syk	_	PROPN	_	Number=Sing	_	_	_	_
8	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	kinases	_	NOUN	_	Number=Plur	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	important	_	ADJ	_	Degree=Pos	_	_	_	_
9	aspect	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	signal	_	ADJ	_	Number=Sing	_	_	_	_
12	transduction	_	NOUN	_	Number=Sing	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	integrins	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	line	_	NOUN	_	Number=Sing	_	_	_	_
7	THP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	either	_	CCONJ	_	_	_	_	_	_
12	integrin	_	ADJ	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	ligation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	beta	_	NOUN	_	Number=Sing	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	integrins	_	NOUN	_	Number=Plur	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
27	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	intense	_	ADJ	_	Degree=Pos	_	_	_	_
32	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
33	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	two	_	NUM	_	NumType=Card	_	_	_	_
36	sets	_	NOUN	_	Number=Plur	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	proteins	_	NOUN	_	Number=Plur	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	about	_	ADV	_	_	_	_	_	_
41	65	_	NUM	_	NumType=Card	_	_	_	_
42	-	_	SYM	_	_	_	_	_	_
43	75	_	NUM	_	NumType=Card	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	120	_	NUM	_	NumType=Card	_	_	_	_
46	-	_	SYM	_	_	_	_	_	_
47	125	_	NUM	_	NumType=Card	_	_	_	_
48	kDa	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	integrin	_	PROPN	_	Number=Sing	_	_	_	_
5	ligation	_	NOUN	_	Number=Sing	_	_	_	_
6	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	translocation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	p50	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	p65	_	NUM	_	Number=Sing	_	_	_	_
15	subunits	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	reporter	_	NOUN	_	Number=Sing	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
36	NF	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappa	_	NOUN	_	Number=Sing	_	_	_	_
39	B	_	NOUN	_	Number=Sing	_	_	_	_
40	sites	_	NOUN	_	Number=Plur	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	levels	_	NOUN	_	Number=Plur	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
48	for	_	ADP	_	_	_	_	_	_
49	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	early	_	ADJ	_	Degree=Pos	_	_	_	_
52	genes	_	NOUN	_	Number=Plur	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	including	_	VERB	_	VerbForm=Ger	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
57	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
58	(	_	PUNCT	_	_	_	_	_	_
59	IL	_	PROPN	_	Number=Sing	_	_	_	_
60	)	_	PUNCT	_	_	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	1	_	NUM	_	NumType=Card	_	_	_	_
63	beta	_	NOUN	_	Number=Sing	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
3	kinase	_	NOUN	_	Number=Sing	_	_	_	_
4	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
5	genistein	_	VERB	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	herbimycin	_	NOUN	_	Number=Sing	_	_	_	_
8	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	block	_	NOUN	_	Number=Sing	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	integrin	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
15	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	increases	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	beta	_	NOUN	_	Number=Sing	_	_	_	_
23	message	_	NOUN	_	Number=Sing	_	_	_	_
24	levels	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	causal	_	ADJ	_	Degree=Pos	_	_	_	_
29	relationship	_	NOUN	_	Number=Sing	_	_	_	_
30	between	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	two	_	NUM	_	NumType=Card	_	_	_	_
33	events	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	components	_	NOUN	_	Number=Plur	_	_	_	_
3	tyrosine	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
9	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	paxillin	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	pp125FAK	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	SH2	_	ADJ	_	Number=Sing	_	_	_	_
17	domain	_	NOUN	_	Number=Sing	_	_	_	_
18	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	Syk	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	integrin	_	NOUN	_	Number=Sing	_	_	_	_
5	ligation	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
8	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
10	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Syk	_	PROPN	_	Number=Sing	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	FAK	_	NOUN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	paxillin	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	adhering	_	VERB	_	VerbForm=Ger	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	pre-treatment	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	cytochalasin	_	NOUN	_	Number=Sing	_	_	_	_
8	D	_	PROPN	_	Number=Sing	_	_	_	_
9	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
11	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	FAK	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	paxillin	_	NOUN	_	Number=Sing	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	not	_	ADV	_	_	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	Syk	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	while	_	SCONJ	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	beta	_	NOUN	_	Number=Sing	_	_	_	_
26	message	_	NOUN	_	Number=Sing	_	_	_	_
27	induction	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	Syk	_	PROPN	_	Number=Sing	_	_	_	_
7	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	may	_	AUX	_	VerbForm=Fin	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	important	_	ADJ	_	Degree=Pos	_	_	_	_
13	component	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	integrin	_	NOUN	_	Number=Sing	_	_	_	_
17	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
18	pathway	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	levels	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
37	messages	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001735	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	Cryptococcus	_	PROPN	_	Degree=Pos	_	_	_	_
14	neoformans	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	Candida	_	PROPN	_	Number=Sing	_	_	_	_
17	albicans	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	candidiasis	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	cryptococcosis	_	NOUN	_	Number=Sing	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	common	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	persons	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	effect	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	Cryptococcus	_	PROPN	_	Number=Sing	_	_	_	_
22	neoformans	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	Candida	_	PROPN	_	Number=Sing	_	_	_	_
25	albicans	_	NOUN	_	Number=Plur	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	HIV	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
33	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	latently	_	ADJ	_	_	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	OM	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	10.1	_	NUM	_	NumType=Card	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	C.	_	PROPN	_	Number=Sing	_	_	_	_
16	neoformans	_	PROPN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	C.	_	PROPN	_	Number=Sing	_	_	_	_
19	albicans	_	PROPN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	presence	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	pooled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	serum	_	NOUN	_	Number=Sing	_	_	_	_
27	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	ratio	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
32	increase	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	HIV	_	NOUN	_	Number=Sing	_	_	_	_
35	production	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HIV	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	C.	_	PROPN	_	Number=Sing	_	_	_	_
6	neoformans	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	anti-capsular	_	ADJ	_	Degree=Pos	_	_	_	_
11	antibody	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	while	_	SCONJ	_	_	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	both	_	DET	_	_	_	_	_	_
17	organisms	_	NOUN	_	Number=Plur	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	anti-TNF	_	ADJ	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	antibody	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	THP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	plasmid	_	ADJ	_	Degree=Pos	_	_	_	_
10	constructs	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	organisms	_	NOUN	_	Number=Plur	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	HIV	_	PROPN	_	Number=Sing	_	_	_	_
19	long	_	ADJ	_	Degree=Pos	_	_	_	_
20	terminal	_	NOUN	_	Number=Sing	_	_	_	_
21	repeat	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	intact	_	ADJ	_	VerbForm=Ger	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	sequences	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	C.	_	PROPN	_	Number=Sing	_	_	_	_
4	neoformans	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	C.	_	PROPN	_	Number=Sing	_	_	_	_
7	albicans	_	PROPN	_	Number=Plur	_	_	_	_
8	enhance	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	HIV	_	PROPN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	HIV	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	patients	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	such	_	ADJ	_	Degree=Pos	_	_	_	_
8	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
9	may	_	AUX	_	VerbForm=Fin	_	_	_	_
10	further	_	ADV	_	VerbForm=Inf	_	_	_	_
11	impair	_	VERB	_	VerbForm=Inf	_	_	_	_
12	host	_	NOUN	_	Number=Sing	_	_	_	_
13	immunity	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	could	_	AUX	_	VerbForm=Fin	_	_	_	_
16	accelerate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	course	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	disease	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001739	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Sterol	_	NOUN	_	Number=Sing	_	_	_	_
2	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
3	LDL	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	receptor	_	NOUN	_	Degree=Pos	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	normal	_	ADJ	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	CML	_	NOUN	_	Number=Sing	_	_	_	_
14	patients	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Sterol	_	PROPN	_	Number=Sing	_	_	_	_
2	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	element	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	SRE	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
9	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	various	_	ADJ	_	Degree=Pos	_	_	_	_
13	key	_	ADJ	_	Degree=Pos	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	coding	_	NOUN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	especially	_	ADV	_	_	_	_	_	_
18	low	_	ADJ	_	Degree=Pos	_	_	_	_
19	density	_	NOUN	_	Number=Sing	_	_	_	_
20	lipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	LDL	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	receptor	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	3	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	hydroxy-3	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	methylglutaryl	_	ADJ	_	Number=Sing	_	_	_	_
32	coenzyme	_	NOUN	_	Number=Sing	_	_	_	_
33	A	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	HMG	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	CoA	_	PROPN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	reductase	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	HMG	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	CoA	_	PROPN	_	Number=Sing	_	_	_	_
44	synthase	_	NOUN	_	Number=Sing	_	_	_	_
45	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	to	_	PART	_	_	_	_	_	_
47	play	_	VERB	_	VerbForm=Inf	_	_	_	_
48	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
49	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
50	role	_	NOUN	_	Number=Sing	_	_	_	_
51	in	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	cholesterol	_	NOUN	_	Number=Sing	_	_	_	_
54	feedback	_	NOUN	_	Number=Sing	_	_	_	_
55	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	deranged	_	ADJ	_	Degree=Pos	_	_	_	_
3	cholesterol	_	NOUN	_	Number=Sing	_	_	_	_
4	feedback	_	NOUN	_	Number=Sing	_	_	_	_
5	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
6	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	widely	_	ADV	_	_	_	_	_	_
9	recognised	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	initiation	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADV	_	_	_	_	_	_
13	well	_	ADV	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	progression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	various	_	ADJ	_	Degree=Pos	_	_	_	_
18	types	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	cancers	_	NOUN	_	Number=Plur	_	_	_	_
21	including	_	VERB	_	VerbForm=Ger	_	_	_	_
22	chronic	_	ADJ	_	Number=Sing	_	_	_	_
23	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
24	leukaemia	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	CML	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Consequently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	present	_	ADJ	_	Degree=Pos	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	addressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	existence	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	unique	_	ADJ	_	Degree=Pos	_	_	_	_
19	47	_	NUM	_	NumType=Card	_	_	_	_
20	kDa	_	NOUN	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	having	_	VERB	_	VerbForm=Ger	_	_	_	_
24	affinity	_	NOUN	_	Number=Sing	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
27	SRE	_	NOUN	_	Number=Sing	_	_	_	_
28	sequence	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	normal	_	ADJ	_	Degree=Pos	_	_	_	_
33	subjects	_	NOUN	_	Number=Plur	_	_	_	_
34	as	_	ADV	_	_	_	_	_	_
35	well	_	ADV	_	Degree=Pos	_	_	_	_
36	as	_	ADP	_	_	_	_	_	_
37	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
38	absence	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
41	from	_	ADP	_	_	_	_	_	_
42	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
43	CML	_	NOUN	_	Number=Sing	_	_	_	_
44	patients	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	when	_	ADV	_	PronType=Int	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	CML	_	PROPN	_	Number=Sing	_	_	_	_
9	patients	_	NOUN	_	Number=Plur	_	_	_	_
10	achieved	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	complete	_	ADJ	_	Degree=Pos	_	_	_	_
12	haematological	_	ADJ	_	Degree=Pos	_	_	_	_
13	remission	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	CHR	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	through	_	ADP	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	interferon	_	NOUN	_	Number=Sing	_	_	_	_
21	therapy	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	inverse	_	ADJ	_	Degree=Pos	_	_	_	_
5	relationship	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	sterol	_	NOUN	_	Number=Sing	_	_	_	_
11	modulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	LDL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	affinity	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
23	47	_	NUM	_	NumType=Card	_	_	_	_
24	kDa	_	NOUN	_	Number=Sing	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	SRE	_	NOUN	_	Number=Sing	_	_	_	_
29	sequence	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	upon	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	interferon	_	NOUN	_	Number=Sing	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	initiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	phosphatidic	_	ADJ	_	Degree=Pos	_	_	_	_
16	acid	_	NOUN	_	Number=Sing	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	signalling	_	NOUN	_	Number=Sing	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	turn	_	NOUN	_	Number=Sing	_	_	_	_
22	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	affinity	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	47	_	NUM	_	NumType=Card	_	_	_	_
27	kDa	_	NOUN	_	Number=Sing	_	_	_	_
28	sterol	_	NOUN	_	Number=Sing	_	_	_	_
29	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
30	element	_	NOUN	_	Number=Sing	_	_	_	_
31	binding	_	NOUN	_	Number=Sing	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	as	_	ADV	_	_	_	_	_	_
34	well	_	ADV	_	Degree=Pos	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	LDL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	receptor	_	NOUN	_	Number=Sing	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	transcription	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
43	from	_	ADP	_	_	_	_	_	_
44	CML	_	PROPN	_	Number=Sing	_	_	_	_
45	patients	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001741	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	6	_	NUM	_	NumType=Card	_	_	_	_
6	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
10	blood	_	NOUN	_	Number=Sing	_	_	_	_
11	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	C3a	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	C3a	_	PROPN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	desArg	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	anaphylatoxin	_	PROPN	_	Number=Sing	_	_	_	_
3	C3a	_	PROPN	_	Number=Sing	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
6	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	have	_	VERB	_	VerbForm=Inf	_	_	_	_
9	immunomodulatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	effects	_	NOUN	_	Number=Plur	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	number	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	different	_	ADJ	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	types	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	C3a	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	C3a	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	desArg	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	secretion	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	6	_	NUM	_	NumType=Card	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	PBMCs	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	either	_	CCONJ	_	_	_	_	_	_
30	alone	_	ADJ	_	_	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	combination	_	NOUN	_	Number=Sing	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	LPS	_	PROPN	_	Number=Sing	_	_	_	_
36	or	_	CCONJ	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1beta	_	PROPN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	C3a	_	PROPN	_	Number=Sing	_	_	_	_
2	or	_	CCONJ	_	_	_	_	_	_
3	C3a	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	desArg	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	alone	_	ADV	_	_	_	_	_	_
8	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	no	_	DET	_	_	_	_	_	_
10	effect	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	secretion	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	6	_	NUM	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	when	_	ADV	_	PronType=Int	_	_	_	_
4	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	LPS	_	PROPN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1beta	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	C3a	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	C3a	_	PROPN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	desArg	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	6	_	NUM	_	NumType=Card	_	_	_	_
28	release	_	NOUN	_	Number=Sing	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	dose	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
36	manner	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	C3a	_	PROPN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
8	PGE2	_	NOUN	_	Number=Sing	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
15	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	influence	_	NOUN	_	Number=Sing	_	_	_	_
20	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
21	production	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
24	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	potential	_	ADJ	_	Degree=Pos	_	_	_	_
27	role	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	C3a	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	LPS	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1beta	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	IL	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	6	_	NUM	_	NumType=Card	_	_	_	_
47	production	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Indomethacin	_	PROPN	_	Number=Sing	_	_	_	_
2	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
4	release	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	but	_	CCONJ	_	_	_	_	_	_
7	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	no	_	DET	_	_	_	_	_	_
9	influence	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	effects	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	C3a	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	effects	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	C3a	_	PROPN	_	Number=Sing	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	6	_	NUM	_	NumType=Card	_	_	_	_
27	production	_	NOUN	_	Number=Sing	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	independent	_	ADJ	_	Degree=Pos	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
32	formation	_	NOUN	_	Number=Sing	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	PROPN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	C3a	_	PROPN	_	Number=Sing	_	_	_	_
7	as	_	ADV	_	_	_	_	_	_
8	well	_	ADV	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	C3a	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	desArg	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	LPS	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
19	levels	_	NOUN	_	Number=Plur	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	6	_	NUM	_	NumType=Card	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	PBMCs	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	pertussis	_	ADJ	_	Number=Sing	_	_	_	_
6	toxin	_	NOUN	_	Number=Sing	_	_	_	_
7	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	functions	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	C3a	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	C3a	_	PROPN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	desArg	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	actions	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
24	two	_	NUM	_	NumType=Card	_	_	_	_
25	molecules	_	NOUN	_	Number=Plur	_	_	_	_
26	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	G	_	NUM	_	Number=Sing	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	pathway	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	C3a	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	C3a	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	desArg	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	molecules	_	NOUN	_	Number=Plur	_	_	_	_
3	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	LPS	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	capacity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	intact	_	VERB	_	Number=Sing	_	_	_	_
8	C3a	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	des	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	Arg	_	NOUN	_	Number=Sing	_	_	_	_
15	form	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	exert	_	VERB	_	VerbForm=Inf	_	_	_	_
18	immunmodulatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	effects	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	vitro	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001744	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Towards	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
4	understanding	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
7	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
2	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	one	_	NUM	_	NumType=Card	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	best	_	ADJ	_	Degree=Sup	_	_	_	_
8	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	examples	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
12	development	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	Hans	_	PROPN	_	Number=Sing	_	_	_	_
3	Clevers	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Michael	_	PROPN	_	Number=Sing	_	_	_	_
6	Owen	_	PROPN	_	Number=Sing	_	_	_	_
7	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	how	_	ADV	_	PronType=Int	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cloning	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	encode	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	membrane	_	NOUN	_	Number=Sing	_	_	_	_
20	proteins	_	NOUN	_	Number=Plur	_	_	_	_
21	allows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	identification	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	factors	_	NOUN	_	Number=Plur	_	_	_	_
27	that	_	PRON	_	PronType=Rel	_	_	_	_
28	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
33	T-cell	_	NOUN	_	Degree=Pos	_	_	_	_
34	genes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Such	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	key	_	ADJ	_	Degree=Pos	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	development	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	mature	_	ADJ	_	Degree=Pos	_	_	_	_
14	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
15	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	functioning	_	VERB	_	VerbForm=Ger	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	'	_	PUNCT	_	_	_	_	_	_
20	master	_	NOUN	_	Number=Sing	_	_	_	_
21	regulators	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	'	_	PUNCT	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001755	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
7	A	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	gamma	_	NOUN	_	Number=Sing	_	_	_	_
18	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	through	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
5	+/	_	SYM	_	_	_	_	_	_
6	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
7	pathway	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	essential	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	many	_	ADJ	_	Degree=Pos	_	_	_	_
15	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	conserved	_	VERB	_	Degree=Pos	_	_	_	_
3	cis	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	acting	_	VERB	_	Number=Sing	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	GGAAAA	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	sequence	_	NOUN	_	Number=Sing	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	involved	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
25	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
26	+	_	CCONJ	_	_	_	_	_	_
27	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	identification	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	importance	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	same	_	ADJ	_	Degree=Pos	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	non-cytokine	_	ADJ	_	Degree=Pos	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	gamma	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	TCRG	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Results	_	NOUN	_	Number=Plur	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	site	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	mutations	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
9	mobility	_	NOUN	_	Number=Sing	_	_	_	_
10	shift	_	NOUN	_	Number=Sing	_	_	_	_
11	assays	_	NOUN	_	Number=Plur	_	_	_	_
12	strongly	_	ADV	_	_	_	_	_	_
13	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	sequence	_	NOUN	_	Number=Sing	_	_	_	_
17	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	TCRG	_	NOUN	_	Number=Sing	_	_	_	_
26	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	explanation	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	previous	_	ADJ	_	Degree=Pos	_	_	_	_
9	observation	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	SCONJ	_	PronType=Rel	_	_	_	_
11	TCRG	_	PROPN	_	Number=Sing	_	_	_	_
12	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
13	levels	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	not	_	ADV	_	_	_	_	_	_
17	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
18	levels	_	NOUN	_	Number=Plur	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	T	_	NUM	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	beta	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	ionomycin	_	ADJ	_	Degree=Pos	_	_	_	_
32	treatment	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001757	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Ex	_	NOUN	_	Number=Sing	_	_	_	_
2	vivo	_	NOUN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	tumor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	draining	_	VERB	_	VerbForm=Ger	_	_	_	_
8	lymph	_	NOUN	_	Number=Sing	_	_	_	_
9	node	_	NOUN	_	Number=Sing	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	reverses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	defects	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	signal	_	NOUN	_	Number=Sing	_	_	_	_
16	transduction	_	NOUN	_	Number=Sing	_	_	_	_
17	molecules	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	adoptive	_	ADJ	_	Degree=Pos	_	_	_	_
3	transfer	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	tumor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	draining	_	VERB	_	VerbForm=Ger	_	_	_	_
8	lymph	_	NOUN	_	Number=Sing	_	_	_	_
9	node	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	LN	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	T	_	X	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	ex	_	NOUN	_	Number=Sing	_	_	_	_
17	vivo	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	anti-CD3	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	X	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	regression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	poorly	_	ADJ	_	_	_	_	_	_
34	immunogenic	_	ADJ	_	Degree=Pos	_	_	_	_
35	murine	_	NOUN	_	Number=Sing	_	_	_	_
36	melanoma	_	NOUN	_	Number=Sing	_	_	_	_
37	D5	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	efficacy	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	LN	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	augmented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	when	_	ADV	_	PronType=Int	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	sensitizing	_	ADJ	_	Degree=Pos	_	_	_	_
13	tumor	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	genetically	_	ADV	_	_	_	_	_	_
17	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	variant	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	D5G6	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	secretes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	colony	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	anti-CD3/IL-2-activated	_	ADJ	_	Degree=Pos	_	_	_	_
5	LN	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	adoptive	_	ADJ	_	Degree=Pos	_	_	_	_
9	transfer	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	freshly	_	ADV	_	_	_	_	_	_
12	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	tumor	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	draining	_	VERB	_	VerbForm=Ger	_	_	_	_
16	LN	_	NOUN	_	Number=Sing	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	no	_	DET	_	_	_	_	_	_
21	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	acquisition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	antitumor	_	NOUN	_	Number=Sing	_	_	_	_
8	function	_	NOUN	_	Number=Sing	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	ex	_	NOUN	_	Number=Sing	_	_	_	_
11	vivo	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	modifications	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	signal	_	ADJ	_	Number=Sing	_	_	_	_
19	transduction	_	NOUN	_	Number=Sing	_	_	_	_
20	capacity	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
25	kinases	_	NOUN	_	Number=Plur	_	_	_	_
26	p56lck	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	p59fyn	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
36	family	_	NOUN	_	Number=Sing	_	_	_	_
37	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	tumor	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	draining	_	VERB	_	VerbForm=Ger	_	_	_	_
43	LN	_	NOUN	_	Number=Sing	_	_	_	_
44	T	_	NOUN	_	Number=Sing	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p56lck	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	p59fyn	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	tumor	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	draining	_	VERB	_	VerbForm=Ger	_	_	_	_
13	than	_	ADP	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	normal	_	ADJ	_	Degree=Pos	_	_	_	_
16	LN	_	NOUN	_	Number=Sing	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	production	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	substrates	_	NOUN	_	Number=Plur	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	markedly	_	ADV	_	_	_	_	_	_
28	depressed	_	ADJ	_	Degree=Pos	_	_	_	_
29	following	_	VERB	_	VerbForm=Ger	_	_	_	_
30	anti-CD3	_	ADJ	_	Degree=Pos	_	_	_	_
31	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	5	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	day	_	NOUN	_	Number=Sing	_	_	_	_
5	anti-CD3/IL	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	p56lck	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	p59fyn	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
18	kinase	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	p56lck	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	p59fyn	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	tyrosine	_	ADJ	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	T	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	LN	_	PROPN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	drained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	D5G6	_	NOUN	_	Number=Sing	_	_	_	_
26	than	_	SCONJ	_	_	_	_	_	_
27	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
28	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	D5	_	NUM	_	Number=Sing	_	_	_	_
33	tumors	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	Rel	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Rel	_	NOUN	_	Number=Sing	_	_	_	_
13	A	_	NOUN	_	Number=Sing	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	normal	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	freshly	_	ADV	_	_	_	_	_	_
18	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	tumor	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	draining	_	VERB	_	VerbForm=Ger	_	_	_	_
22	LN	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	as	_	SCONJ	_	_	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	DNA	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	binding	_	VERB	_	Number=Sing	_	_	_	_
31	activity	_	NOUN	_	Number=Sing	_	_	_	_
32	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
35	mAb	_	NOUN	_	Number=Sing	_	_	_	_
36	or	_	CCONJ	_	_	_	_	_	_
37	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
38	myristate	_	NOUN	_	Number=Sing	_	_	_	_
39	acetate	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	LN	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	D5	_	ADJ	_	NumType=Card	_	_	_	_
8	tumor	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	translocation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	recovery	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	transduction	_	NOUN	_	Number=Sing	_	_	_	_
12	through	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	CD3	_	PROPN	_	Number=Sing	_	_	_	_
19	complex	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	LN	_	PROPN	_	Number=Sing	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	ex	_	NOUN	_	Number=Sing	_	_	_	_
26	vivo	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	acquisition	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	antitumor	_	NOUN	_	Number=Sing	_	_	_	_
34	function	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001758	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	tumor	_	NOUN	_	Number=Sing	_	_	_	_
8	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	line	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	independent	_	ADJ	_	Degree=Pos	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	kinase	_	NOUN	_	Number=Sing	_	_	_	_
22	A	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	kinase	_	NOUN	_	Number=Sing	_	_	_	_
26	C	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	Ca	_	PROPN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	+)-	_	SYM	_	_	_	_	_	_
33	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	kinases	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	DNA	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
7	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	able	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	control	_	VERB	_	VerbForm=Inf	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	number	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	including	_	VERB	_	VerbForm=Ger	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
22	virus	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	HIV	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	upon	_	ADP	_	_	_	_	_	_
12	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
13	treatment	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
16	esters	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
20	tumor	_	NOUN	_	Number=Sing	_	_	_	_
21	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	TNF	_	PROPN	_	Number=Sing	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	work	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
10	events	_	NOUN	_	Number=Plur	_	_	_	_
11	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	TNF	_	PROPN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	line	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
32	subclone	_	NOUN	_	Number=Sing	_	_	_	_
33	JCT6	_	PROPN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	which	_	PRON	_	PronType=Rel	_	_	_	_
36	presents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	PKA	_	PROPN	_	Number=Sing	_	_	_	_
42	transduction	_	NOUN	_	Number=Sing	_	_	_	_
43	pathway	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	both	_	DET	_	_	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	lines	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
11	ester	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	TNF	_	PROPN	_	Number=Sing	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	able	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	PROPN	_	Number=Sing	_	_	_	_
22	B.	_	PROPN	_	Number=Sing	_	_	_	_
23	Phorbol	_	PROPN	_	Number=Sing	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	positively	_	ADV	_	_	_	_	_	_
27	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
30	+	_	SYM	_	_	_	_	_	_
31	influx	_	NOUN	_	Number=Sing	_	_	_	_
32	while	_	SCONJ	_	_	_	_	_	_
33	TNF	_	PROPN	_	Number=Sing	_	_	_	_
34	alpha	_	NOUN	_	Number=Sing	_	_	_	_
35	activation	_	NOUN	_	Number=Sing	_	_	_	_
36	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
37	not	_	PART	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	while	_	SCONJ	_	_	_	_	_	_
4	PMA	_	PROPN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	PKC	_	PROPN	_	Number=Sing	_	_	_	_
11	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
12	staurosporin	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	TNF	_	PROPN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	effect	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	unchanged	_	ADJ	_	Degree=Pos	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	alpha	_	PROPN	_	Number=Sing	_	_	_	_
3	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
6	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
7	production	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
16	activators	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
4	activators	_	NOUN	_	Number=Plur	_	_	_	_
5	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	TNF	_	PROPN	_	Number=Sing	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	none	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	major	_	ADJ	_	Degree=Pos	_	_	_	_
22	signal	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	mediating	_	NOUN	_	VerbForm=Ger	_	_	_	_
25	kinases	_	NOUN	_	Number=Plur	_	_	_	_
26	such	_	ADJ	_	Degree=Pos	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	kinase	_	NOUN	_	Number=Sing	_	_	_	_
30	C	_	PROPN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	PKC	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	kinase	_	NOUN	_	Number=Sing	_	_	_	_
37	A	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	or	_	CCONJ	_	_	_	_	_	_
40	Ca	_	PROPN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	2	_	NUM	_	NumType=Card	_	_	_	_
43	+)-	_	SYM	_	_	_	_	_	_
44	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	kinases	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
7	acidification	_	NOUN	_	Number=Sing	_	_	_	_
8	facilitated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	PKC	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
32	kappa	_	VERB	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
35	without	_	SCONJ	_	_	_	_	_	_
36	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	kappa	_	NOUN	_	Number=Sing	_	_	_	_
41	B	_	NOUN	_	Number=Sing	_	_	_	_
42	translocation	_	NOUN	_	Number=Sing	_	_	_	_
43	step	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001760	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
2	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	cycle	_	NOUN	_	Number=Sing	_	_	_	_
6	progression	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	humans	_	NOUN	_	Number=Plur	_	_	_	_
9	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	methyl	_	ADJ	_	Number=Sing	_	_	_	_
12	tertiary	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	butyl	_	NOUN	_	Number=Sing	_	_	_	_
15	ether	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	benzene	_	VERB	_	Number=Sing	_	_	_	_
18	contaminating	_	VERB	_	VerbForm=Ger	_	_	_	_
19	water	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	1	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	In	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	hypothesized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	individuals	_	NOUN	_	Number=Plur	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	certain	_	ADJ	_	Degree=Pos	_	_	_	_
13	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
14	makeup	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	MTBE	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	benzene	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	metabolites	_	NOUN	_	Number=Plur	_	_	_	_
22	act	_	NOUN	_	Number=Sing	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	adducts	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	may	_	AUX	_	VerbForm=Fin	_	_	_	_
27	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
28	programmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	death	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	2	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	involved	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	group	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	60	_	NUM	_	NumType=Card	_	_	_	_
10	male	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	female	_	ADJ	_	Degree=Pos	_	_	_	_
13	subjects	_	NOUN	_	Number=Plur	_	_	_	_
14	who	_	PRON	_	PronType=Rel	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	exposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	MTBE	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	benzene	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	contaminated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	water	_	NOUN	_	Number=Sing	_	_	_	_
24	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
25	up	_	ADP	_	_	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	76	_	NUM	_	NumType=Card	_	_	_	_
28	PPB	_	NOUN	_	Number=Plur	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	MTBE	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	14	_	NUM	_	NumType=Card	_	_	_	_
33	PPB	_	NOUN	_	Number=Sing	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	benzene	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	period	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	5	_	NUM	_	NumType=Card	_	_	_	_
42	to	_	ADP	_	_	_	_	_	_
43	8	_	NUM	_	NumType=Card	_	_	_	_
44	years	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	comparison	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	recruited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	control	_	NOUN	_	Number=Sing	_	_	_	_
8	group	_	NOUN	_	Number=Sing	_	_	_	_
9	consisting	_	VERB	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	32	_	NUM	_	NumType=Card	_	_	_	_
12	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
13	males	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	females	_	NOUN	_	Number=Plur	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	similar	_	ADJ	_	Degree=Pos	_	_	_	_
18	age	_	NOUN	_	Number=Sing	_	_	_	_
19	distribution	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	without	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	history	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	exposure	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	MTBE	_	NOUN	_	Number=Sing	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	benzene	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	3	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	Peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
4	blood	_	NOUN	_	Number=Sing	_	_	_	_
5	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	PBL	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	both	_	DET	_	_	_	_	_	_
11	groups	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	tested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	percentage	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	cycle	_	NOUN	_	Number=Sing	_	_	_	_
23	progression	_	NOUN	_	Number=Sing	_	_	_	_
24	using	_	VERB	_	VerbForm=Ger	_	_	_	_
25	flow	_	NOUN	_	Number=Sing	_	_	_	_
26	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	4	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	When	_	ADV	_	PronType=Int	_	_	_	_
4	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
5	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	individuals	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	control	_	NOUN	_	Number=Sing	_	_	_	_
17	group	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	statistically	_	ADV	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	significant	_	ADJ	_	Degree=Pos	_	_	_	_
22	differences	_	NOUN	_	Number=Plur	_	_	_	_
23	between	_	ADP	_	_	_	_	_	_
24	each	_	DET	_	_	_	_	_	_
25	mean	_	NOUN	_	Number=Sing	_	_	_	_
26	group	_	NOUN	_	Number=Sing	_	_	_	_
27	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	26.4	_	NUM	_	NumType=Card	_	_	_	_
31	+/-	_	SYM	_	_	_	_	_	_
32	1.8	_	NUM	_	NumType=Card	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	12.1	_	NUM	_	NumType=Card	_	_	_	_
35	+/-	_	SYM	_	_	_	_	_	_
36	1.3	_	NUM	_	NumType=Card	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	respectively	_	ADV	_	_	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
42	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	rate	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	80.5	_	NUM	_	NumType=Card	_	_	_	_
49	%	_	SYM	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
52	individuals	_	NOUN	_	Number=Plur	_	_	_	_
53	(	_	PUNCT	_	_	_	_	_	_
54	P	_	NOUN	_	Number=Sing	_	_	_	_
55	<	_	PUNCT	_	_	_	_	_	_
56	0.0001	_	NUM	_	NumType=Card	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	Mann	_	PROPN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	Whitney	_	PROPN	_	Number=Sing	_	_	_	_
61	U	_	PROPN	_	Number=Sing	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	Test	_	PROPN	_	Number=Sing	_	_	_	_
64	)	_	PUNCT	_	_	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	MTBE	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	benzene	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	attributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	discrete	_	NOUN	_	Number=Sing	_	_	_	_
12	block	_	NOUN	_	Number=Sing	_	_	_	_
13	within	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	cycle	_	NOUN	_	Number=Sing	_	_	_	_
17	progression	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	cycle	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	PBL	_	NOUN	_	Number=Sing	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	chemically	_	ADV	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	individuals	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	between	_	ADP	_	_	_	_	_	_
16	20	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	50	_	NUM	_	NumType=Card	_	_	_	_
19	%	_	SYM	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	accumulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	at	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	S	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	G2	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	M	_	NOUN	_	Number=Sing	_	_	_	_
31	boundaries	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	5	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	One	_	NUM	_	NumType=Card	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	signaling	_	VERB	_	Number=Sing	_	_	_	_
7	molecules	_	NOUN	_	Number=Plur	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	programmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	death	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	Kappa	_	PROPN	_	Number=Sing	_	_	_	_
17	-B	_	PROPN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	PROPN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	one	_	NUM	_	NumType=Card	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	many	_	ADJ	_	Degree=Pos	_	_	_	_
12	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
13	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
14	for	_	SCONJ	_	_	_	_	_	_
15	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	death	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	MTBE	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	benzene	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Indeed	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	addition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	pyrrolidine	_	NOUN	_	Number=Sing	_	_	_	_
13	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	PDTC	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	chemically	_	ADV	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	group	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	capable	_	ADJ	_	Degree=Pos	_	_	_	_
29	of	_	SCONJ	_	_	_	_	_	_
30	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
31	programmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	death	_	NOUN	_	Number=Sing	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	40	_	NUM	_	NumType=Card	_	_	_	_
36	%	_	SYM	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	reversal	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	almost	_	ADV	_	_	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	control	_	NOUN	_	Number=Sing	_	_	_	_
9	level	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	may	_	AUX	_	VerbForm=Fin	_	_	_	_
19	indicate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	involvement	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
23	signaling	_	VERB	_	Number=Sing	_	_	_	_
24	molecule	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	MTBE	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	benzene	_	NOUN	_	Number=Sing	_	_	_	_
29	induction	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	programmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	death	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001767	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Role	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	EGR1	_	PROPN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	stimulus	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	CD44	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	early	_	ADJ	_	Degree=Pos	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	egr	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	EGR1	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	that	_	DET	_	PronType=Rel	_	_	_	_
17	links	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	antigen	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	BCR	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	signals	_	NOUN	_	Number=Plur	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	events	_	NOUN	_	Number=Plur	_	_	_	_
31	through	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	regulation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	previously	_	ADV	_	_	_	_	_	_
36	unidentified	_	ADJ	_	Degree=Pos	_	_	_	_
37	target	_	NOUN	_	Number=Sing	_	_	_	_
38	genes	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
9	homing	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	migration	_	NOUN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	CD44	_	NOUN	_	Number=Sing	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	target	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	EGR1	_	PROPN	_	Number=Sing	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	B	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	BCR	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	increases	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	CD44	_	PROPN	_	Number=Sing	_	_	_	_
7	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	EGR1	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	expressing	_	NOUN	_	Number=Sing	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	not	_	ADV	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	nonexpressing	_	ADJ	_	Degree=Pos	_	_	_	_
24	subclones	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	line	_	NOUN	_	Number=Sing	_	_	_	_
31	WEHI	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	231	_	NUM	_	NumType=Card	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Kinetics	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	egr	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	appearance	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	EGR1	_	NOUN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	precede	_	VERB	_	Number=Sing	_	_	_	_
15	CD44	_	PROPN	_	Number=Sing	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
19	within	_	ADP	_	_	_	_	_	_
20	30	_	NUM	_	NumType=Card	_	_	_	_
21	min	_	NOUN	_	Number=Plur	_	_	_	_
22	after	_	ADP	_	_	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	EGR1	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
29	subclone	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	single	_	ADJ	_	Degree=Pos	_	_	_	_
3	EGR1	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	motif	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	at	_	ADP	_	_	_	_	_	_
9	bp	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	301	_	NUM	_	NumType=Card	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	CD44	_	NOUN	_	Number=Sing	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	CD44	_	PROPN	_	Number=Sing	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	chloramphenicol	_	NOUN	_	Number=Sing	_	_	_	_
8	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
9	reporter	_	NOUN	_	Number=Sing	_	_	_	_
10	construct	_	VERB	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	egr	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	vector	_	NOUN	_	Number=Sing	_	_	_	_
18	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	6.5	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	8.5	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	fold	_	NOUN	_	Number=Sing	_	_	_	_
27	induction	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	relative	_	ADV	_	_	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	empty	_	ADJ	_	Degree=Pos	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	vector	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	EGR1	_	PROPN	_	Number=Sing	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	motif	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	stimulus	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	CD44	_	NOUN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
21	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
22	reporter	_	NOUN	_	Number=Sing	_	_	_	_
23	construct	_	VERB	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	nontransformed	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
26	B	_	PROPN	_	Number=Sing	_	_	_	_
27	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	EGR1	_	NOUN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	vector	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	B	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	line	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	EGR1	_	PROPN	_	Number=Sing	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	intermediary	_	ADJ	_	Degree=Pos	_	_	_	_
8	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
9	BCR	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	signals	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	CD44	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	relevance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	events	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	BCR	_	PROPN	_	Number=Sing	_	_	_	_
9	signal	_	NOUN	_	Number=Sing	_	_	_	_
10	transduction	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	antigen	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
20	immune	_	NOUN	_	Number=Sing	_	_	_	_
21	responses	_	NOUN	_	Number=Plur	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001772	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
3	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
6	molecule	_	NOUN	_	Degree=Pos	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	venous	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	arterial	_	ADJ	_	Degree=Pos	_	_	_	_
12	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	U	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	937	_	NUM	_	NumType=Card	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
10	molecule	_	NOUN	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
15	venous	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	arterial	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	HUAECs	_	NOUN	_	Number=Plur	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	tumor	_	NOUN	_	Number=Sing	_	_	_	_
29	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	TNF	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	LPS	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	LPS	_	PROPN	_	Number=Sing	_	_	_	_
4	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
8	molecule	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	surface	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	U	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	SYM	_	_	_	_	_	_
21	937	_	NUM	_	NumType=Card	_	_	_	_
22	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	like	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	HUVECs	_	PROPN	_	Number=Sing	_	_	_	_
28	but	_	CCONJ	_	_	_	_	_	_
29	not	_	ADV	_	_	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	HUAECs	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Antibody	_	PROPN	_	Number=Sing	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
7	at	_	ADV	_	_	_	_	_	_
8	least	_	ADV	_	Degree=Sup	_	_	_	_
9	75	_	NUM	_	NumType=Card	_	_	_	_
10	%	_	SYM	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	mediated	_	VERB	_	Degree=Pos	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	U	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	937	_	NUM	_	NumType=Card	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	surface	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	HUAECs	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Pyrrolidinedithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
5	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
6	MG	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	132	_	NUM	_	NumType=Card	_	_	_	_
9	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	TNF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	LPS	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	U	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	937	_	NUM	_	NumType=Card	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	HUVECs	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	agents	_	NOUN	_	Number=Plur	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	significantly	_	ADV	_	_	_	_	_	_
5	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	TNF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	LPS	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	increases	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	HUVEC	_	PROPN	_	Number=Sing	_	_	_	_
15	surface	_	NOUN	_	Number=Sing	_	_	_	_
16	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	pyrrolidinedithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	neither	_	CCONJ	_	_	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	LPS	_	PROPN	_	Number=Sing	_	_	_	_
7	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	HUAECs	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	both	_	CCONJ	_	_	_	_	_	_
6	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
8	molecule	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	E-selectin	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	HUVECs	_	PROPN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	HUAECs	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	only	_	ADV	_	_	_	_	_	_
21	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
23	molecule	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	no	_	DET	_	_	_	_	_	_
7	difference	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	pattern	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	between	_	ADP	_	_	_	_	_	_
21	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	HUAECs	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	novel	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	striking	_	VERB	_	VerbForm=Ger	_	_	_	_
8	insensitivity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	arterial	_	NOUN	_	Degree=Pos	_	_	_	_
11	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	effects	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	LPS	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
23	between	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	ability	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	HUAECs	_	NOUN	_	Number=Plur	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	upregulate	_	VERB	_	VerbForm=Inf	_	_	_	_
30	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_
39	Document	_	NOUN	_	Number=Sing	_	_	_	_
40	003001780	_	NUM	_	NumType=Card	_	_	_	_
41	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Surfactant	_	ADJ	_	Number=Sing	_	_	_	_
2	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	biophysical	_	ADJ	_	Degree=Pos	_	_	_	_
5	properties	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	pulmonary	_	ADJ	_	Degree=Pos	_	_	_	_
8	surfactant	_	NOUN	_	Number=Sing	_	_	_	_
9	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	immunomodulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	both	_	DET	_	_	_	_	_	_
6	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	Exosurf	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	natural	_	ADJ	_	Degree=Pos	_	_	_	_
13	surfactant	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	Survanta	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	downregulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	endotoxin-stimulated	_	ADJ	_	Degree=Pos	_	_	_	_
19	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
20	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
21	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
22	levels	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	products	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	tumor	_	NOUN	_	Number=Sing	_	_	_	_
28	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	[	_	PUNCT	_	_	_	_	_	_
33	TNF	_	PROPN	_	Number=Sing	_	_	_	_
34	]	_	PUNCT	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	beta	_	NOUN	_	Number=Sing	_	_	_	_
41	[	_	PUNCT	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	]	_	PUNCT	_	_	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	6	_	NUM	_	NumType=Card	_	_	_	_
50	[	_	PUNCT	_	_	_	_	_	_
51	IL	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	6	_	NUM	_	NumType=Card	_	_	_	_
54	]	_	PUNCT	_	_	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	in	_	ADP	_	_	_	_	_	_
57	human	_	ADJ	_	Degree=Pos	_	_	_	_
58	alveolar	_	NOUN	_	Degree=Pos	_	_	_	_
59	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	Exosurf	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	Survanta	_	PROPN	_	Number=Sing	_	_	_	_
12	suppress	_	VERB	_	Number=Sing	_	_	_	_
13	TNF	_	PROPN	_	Number=Sing	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	secretion	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	85	_	NUM	_	NumType=Card	_	_	_	_
19	+/-	_	SYM	_	_	_	_	_	_
20	4	_	NUM	_	NumType=Card	_	_	_	_
21	%	_	SYM	_	Number=Sing	_	_	_	_
22	mean	_	NUM	_	NumType=Card	_	_	_	_
23	percent	_	NOUN	_	Number=Sing	_	_	_	_
24	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
25	+/-	_	SYM	_	_	_	_	_	_
26	SEM	_	NOUN	_	Number=Sing	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	Exosurf	_	PROPN	_	Number=Sing	_	_	_	_
29	;	_	PUNCT	_	_	_	_	_	_
30	71	_	NUM	_	NumType=Card	_	_	_	_
31	+/-	_	SYM	_	_	_	_	_	_
32	6	_	NUM	_	NumType=Card	_	_	_	_
33	%	_	SYM	_	Number=Sing	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	Survanta	_	PROPN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	THP	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	1	_	NUM	_	NumType=Card	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
46	human	_	ADJ	_	Degree=Pos	_	_	_	_
47	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
48	cell	_	NOUN	_	Number=Sing	_	_	_	_
49	line	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	surfactant	_	ADJ	_	Degree=Pos	_	_	_	_
3	downregulated	_	VERB	_	Degree=Pos	_	_	_	_
4	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
6	production	_	NOUN	_	Number=Sing	_	_	_	_
7	similarly	_	ADV	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	both	_	DET	_	_	_	_	_	_
10	normal	_	ADJ	_	Degree=Pos	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	alveolar	_	NOUN	_	Number=Sing	_	_	_	_
13	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	THP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	line	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
23	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	line	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
29	whether	_	SCONJ	_	_	_	_	_	_
30	surfactant	_	ADJ	_	Number=Sing	_	_	_	_
31	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
33	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Specifically	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	because	_	SCONJ	_	_	_	_	_	_
18	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	regulation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	many	_	ADJ	_	Degree=Pos	_	_	_	_
26	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
28	genes	_	NOUN	_	Number=Plur	_	_	_	_
29	including	_	VERB	_	VerbForm=Ger	_	_	_	_
30	TNF	_	PROPN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	6	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	both	_	DET	_	_	_	_	_	_
8	surfactants	_	NOUN	_	Number=Plur	_	_	_	_
9	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	PROPN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	presence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	p65	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	p50	_	PROPN	_	Number=Sing	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	components	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	LPS	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	THP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	antibody	_	NOUN	_	Number=Sing	_	_	_	_
26	induction	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	supershifts	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	mobility	_	NOUN	_	Number=Sing	_	_	_	_
31	assays	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	suggest	_	VERB	_	VerbForm=Inf	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	surfactant	_	NOUN	_	Number=Sing	_	_	_	_
10	's	_	PART	_	_	_	_	_	_
11	suppressive	_	ADJ	_	Degree=Pos	_	_	_	_
12	effects	_	NOUN	_	Number=Plur	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	regulation	_	NOUN	_	Number=Sing	_	_	_	_
21	through	_	ADP	_	_	_	_	_	_
22	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001782	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	tumor	_	NOUN	_	Number=Sing	_	_	_	_
7	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	B	_	ADJ	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	lines	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	1311	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	base	_	NOUN	_	Number=Sing	_	_	_	_
5	pair	_	NOUN	_	Number=Sing	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	tumor	_	NOUN	_	Number=Sing	_	_	_	_
8	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	fused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	Luc	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	reporter	_	NOUN	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	transient	_	ADJ	_	Degree=Pos	_	_	_	_
31	transfection	_	NOUN	_	Number=Sing	_	_	_	_
32	system	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	three	_	NUM	_	NumType=Card	_	_	_	_
35	TNF	_	NOUN	_	Number=Sing	_	_	_	_
36	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	lines	_	NOUN	_	Number=Plur	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	U937	_	NOUN	_	Number=Sing	_	_	_	_
42	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
43	cell	_	NOUN	_	Number=Sing	_	_	_	_
44	line	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	MLA	_	PROPN	_	Number=Sing	_	_	_	_
48	144	_	NUM	_	NumType=Card	_	_	_	_
49	T	_	NOUN	_	Number=Sing	_	_	_	_
50	cell	_	NOUN	_	Number=Sing	_	_	_	_
51	line	_	NOUN	_	Number=Sing	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	and	_	CCONJ	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	729	_	NUM	_	NumType=Card	_	_	_	_
56	-6	_	NUM	_	NumType=Card	_	_	_	_
57	B	_	NOUN	_	Number=Sing	_	_	_	_
58	cell	_	NOUN	_	Number=Sing	_	_	_	_
59	line	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	full	_	ADJ	_	Degree=Pos	_	_	_	_
3	length	_	NOUN	_	Number=Sing	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	construct	_	NOUN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
11	13	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	myristate	_	NOUN	_	Number=Sing	_	_	_	_
14	acetate	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	PMA	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	each	_	DET	_	_	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	types	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	series	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	5'-	_	ADJ	_	NumType=Card	_	_	_	_
7	truncations	_	NOUN	_	Number=Plur	_	_	_	_
8	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	several	_	ADJ	_	Degree=Pos	_	_	_	_
10	peaks	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	basal	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	PMA	_	NOUN	_	Number=Sing	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	presence	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	several	_	ADJ	_	Degree=Pos	_	_	_	_
22	positive	_	ADJ	_	Degree=Pos	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	negative	_	ADJ	_	Degree=Pos	_	_	_	_
25	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
26	elements	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	PMA	_	PROPN	_	Number=Sing	_	_	_	_
3	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
4	element	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	95	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	36	_	NUM	_	NumType=Card	_	_	_	_
16	bp	_	NOUN	_	Number=Sing	_	_	_	_
17	relative	_	ADV	_	_	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	start	_	NOUN	_	Number=Sing	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Within	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	single	_	ADJ	_	Degree=Pos	_	_	_	_
6	AP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	like	_	ADJ	_	_	_	_	_	_
16	consensus	_	NOUN	_	Number=Sing	_	_	_	_
17	sequences	_	NOUN	_	Number=Plur	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	noted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	AP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	AP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	sites	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	each	_	DET	_	_	_	_	_	_
12	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	double	_	ADJ	_	Degree=Pos	_	_	_	_
16	point	_	NOUN	_	Number=Sing	_	_	_	_
17	mutation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	modest	_	ADJ	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	20	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	SYM	_	_	_	_	_	_
6	50	_	NUM	_	NumType=Card	_	_	_	_
7	%	_	SYM	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	reduction	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	mutation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	mutation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	AP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	markedly	_	ADV	_	_	_	_	_	_
11	diminished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	basal	_	ADJ	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	PMA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Also	_	ADV	_	_	_	_	_	_
2	co	_	X	_	_	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	transfections	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	wild	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	construct	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1/c	_	NUM	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	jun	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	vector	_	NOUN	_	Number=Sing	_	_	_	_
21	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	basal	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	PMA	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001787	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Specific	_	ADJ	_	Degree=Pos	_	_	_	_
2	complex	_	ADJ	_	Degree=Pos	_	_	_	_
3	formation	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	II	_	NUM	_	NumType=Card	_	_	_	_
8	bare	_	VERB	_	Degree=Pos	_	_	_	_
9	lymphocyte	_	NOUN	_	Degree=Pos	_	_	_	_
10	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	transactivators	_	NOUN	_	Number=Plur	_	_	_	_
14	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	RFX5	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	genes	_	NOUN	_	Number=Plur	_	_	_	_
5	defective	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	five	_	NUM	_	NumType=Card	_	_	_	_
9	complementation	_	NOUN	_	Number=Sing	_	_	_	_
10	groups	_	NOUN	_	Number=Plur	_	_	_	_
11	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	class	_	NOUN	_	Number=Sing	_	_	_	_
15	II	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	negative	_	ADJ	_	Degree=Pos	_	_	_	_
18	bare	_	NOUN	_	Degree=Pos	_	_	_	_
19	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
20	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	corresponding	_	VERB	_	Degree=Pos	_	_	_	_
23	laboratory	_	ADJ	_	Number=Sing	_	_	_	_
24	mutants	_	NOUN	_	Number=Plur	_	_	_	_
25	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
27	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	RFX5	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	member	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	RFX	_	PROPN	_	Number=Sing	_	_	_	_
16	family	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	DNA	_	NOUN	_	Number=Sing	_	_	_	_
19	binding	_	VERB	_	Number=Sing	_	_	_	_
20	proteins	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	large	_	ADJ	_	Degree=Pos	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	defined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	acidic	_	ADJ	_	Degree=Pos	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	domain	_	NOUN	_	Number=Sing	_	_	_	_
17	;	_	PUNCT	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	DNA	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
3	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
4	regions	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	RFX5	_	NOUN	_	Number=Sing	_	_	_	_
7	fused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	GAL4	_	PROPN	_	Number=Sing	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	domain	_	NOUN	_	Number=Sing	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	reporter	_	NOUN	_	Number=Sing	_	_	_	_
19	construct	_	NOUN	_	Number=Sing	_	_	_	_
20	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	GAL4	_	NOUN	_	Number=Sing	_	_	_	_
22	sites	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
26	assay	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	Raji	_	ADJ	_	Number=Sing	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	line	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
5	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	only	_	ADV	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	conjunction	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	interferon	_	NOUN	_	Number=Sing	_	_	_	_
16	gamma	_	NOUN	_	Number=Sing	_	_	_	_
17	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	condition	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	which	_	DET	_	PronType=Rel	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	both	_	CCONJ	_	_	_	_	_	_
26	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	class	_	NOUN	_	Number=Sing	_	_	_	_
29	II	_	NUM	_	NumType=Card	_	_	_	_
30	major	_	ADJ	_	Degree=Pos	_	_	_	_
31	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
32	complex	_	ADJ	_	Degree=Pos	_	_	_	_
33	surface	_	NOUN	_	Number=Sing	_	_	_	_
34	proteins	_	NOUN	_	Number=Plur	_	_	_	_
35	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	active	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	RJ2.2.5	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vitro	_	NOUN	_	Number=Sing	_	_	_	_
14	mutagenized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	derivative	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Raji	_	PROPN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	both	_	DET	_	_	_	_	_	_
21	copies	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	defective	_	ADJ	_	Degree=Pos	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	RFX5	_	PROPN	_	Number=Sing	_	_	_	_
6	fusion	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	could	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	restored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	RJ2.2.5	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	direct	_	ADJ	_	Degree=Pos	_	_	_	_
5	interaction	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	RFX5	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	yeast	_	ADJ	_	Number=Sing	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	far	_	ADV	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	Western	_	ADJ	_	Degree=Pos	_	_	_	_
22	blot	_	NOUN	_	Number=Sing	_	_	_	_
23	assays	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	RFX5	_	NOUN	_	Number=Sing	_	_	_	_
4	can	_	AUX	_	VerbForm=Fin	_	_	_	_
5	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	only	_	ADV	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	RFX5	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
4	associate	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	form	_	VERB	_	VerbForm=Inf	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	complex	_	NOUN	_	Number=Sing	_	_	_	_
9	capable	_	ADJ	_	Degree=Pos	_	_	_	_
10	of	_	SCONJ	_	_	_	_	_	_
11	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	class	_	NOUN	_	Number=Sing	_	_	_	_
15	II	_	NUM	_	NumType=Card	_	_	_	_
16	major	_	ADJ	_	Degree=Pos	_	_	_	_
17	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
18	complex	_	NOUN	_	Number=Sing	_	_	_	_
19	promoters	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	complex	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	specificity	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	domain	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	RFX5	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	general	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	apparatus	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	recruited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	acidic	_	ADJ	_	Degree=Pos	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	domain	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001792	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Redox	_	NOUN	_	Number=Sing	_	_	_	_
2	status	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	influences	_	NOUN	_	Number=Plur	_	_	_	_
6	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	NF	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	translocation	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	HIV	_	ADJ	_	Number=Sing	_	_	_	_
16	long	_	ADJ	_	Degree=Pos	_	_	_	_
17	terminal	_	NOUN	_	Number=Sing	_	_	_	_
18	repeat	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	lines	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	events	_	NOUN	_	Number=Plur	_	_	_	_
10	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	mediated	_	VERB	_	Degree=Pos	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	translocation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
30	upon	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
33	redox	_	NOUN	_	Number=Sing	_	_	_	_
34	status	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	phenolic	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	lipid	_	ADJ	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	soluble	_	ADJ	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	chain	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	breaking	_	NOUN	_	Number=Sing	_	_	_	_
12	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	butylated	_	ADJ	_	Number=Sing	_	_	_	_
15	hydroxyanisole	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	BHA	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	nordihydroquairetic	_	ADJ	_	Degree=Pos	_	_	_	_
21	acid	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	tocopherol	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
29	E	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	show	_	VERB	_	VerbForm=Inf	_	_	_	_
33	that	_	SCONJ	_	_	_	_	_	_
34	peroxyl	_	NOUN	_	_	_	_	_	_
35	radical	_	ADJ	_	Degree=Pos	_	_	_	_
36	scavenging	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	PMA	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	or	_	CCONJ	_	_	_	_	_	_
43	TNF	_	ADJ	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	blocks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	functions	_	NOUN	_	Number=Plur	_	_	_	_
50	depending	_	VERB	_	VerbForm=Ger	_	_	_	_
51	on	_	ADP	_	_	_	_	_	_
52	NF	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	kappa	_	NOUN	_	Number=Sing	_	_	_	_
55	B	_	NOUN	_	Number=Sing	_	_	_	_
56	activation	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	BHA	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
6	not	_	ADV	_	_	_	_	_	_
7	only	_	ADV	_	_	_	_	_	_
8	PMA	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	TNF	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	also	_	ADV	_	_	_	_	_	_
17	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	concomitant	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	activity	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	both	_	CCONJ	_	_	_	_	_	_
36	lymphoblastoid	_	PROPN	_	Number=Sing	_	_	_	_
37	T	_	PROPN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	J.	_	PROPN	_	Number=Sing	_	_	_	_
40	Jhan	_	PROPN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	monocytic	_	NOUN	_	Number=Sing	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	U937	_	NOUN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	cell	_	NOUN	_	Number=Sing	_	_	_	_
48	lines	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	true	_	ADJ	_	Degree=Pos	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	KBF	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	p50	_	NUM	_	NumType=Card	_	_	_	_
9	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	U937	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Secretion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TNF	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	product	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	another	_	DET	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	BHA	_	PROPN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	PMA	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	U937	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	anti-oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	BHA	_	PROPN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	increase	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	thiol	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	content	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	stimulated	_	VERB	_	Degree=Pos	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	whereas	_	SCONJ	_	_	_	_	_	_
27	TNF	_	ADJ	_	Number=Sing	_	_	_	_
28	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
29	itself	_	PRON	_	Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
30	barely	_	ADV	_	_	_	_	_	_
31	modified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
34	thiol	_	NOUN	_	Number=Sing	_	_	_	_
35	level	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
2	stress	_	NOUN	_	Number=Sing	_	_	_	_
3	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	addition	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	culture	_	NOUN	_	Number=Sing	_	_	_	_
12	medium	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	J.Jhan	_	PROPN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	U937	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	could	_	AUX	_	VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	by	_	ADP	_	VerbForm=Inf	_	_	_	_
21	itself	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs|Reflex=Yes	_	_	_	_
22	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TNF	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	PMA	_	PROPN	_	Number=Sing	_	_	_	_
8	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	through	_	ADP	_	_	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	changes	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	redox	_	NOUN	_	Number=Sing	_	_	_	_
25	status	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Rather	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	TNF	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	PMA	_	PROPN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	exert	_	VERB	_	VerbForm=Inf	_	_	_	_
8	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	only	_	ADV	_	_	_	_	_	_
11	if	_	SCONJ	_	_	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	appropriate	_	ADJ	_	Degree=Pos	_	_	_	_
17	redox	_	NOUN	_	Number=Sing	_	_	_	_
18	status	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	because	_	SCONJ	_	_	_	_	_	_
21	prior	_	ADJ	_	Degree=Pos	_	_	_	_
22	modification	_	NOUN	_	Number=Sing	_	_	_	_
23	toward	_	ADP	_	_	_	_	_	_
24	reduction	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	BHA	_	NOUN	_	Number=Sing	_	_	_	_
27	treatment	_	NOUN	_	Number=Sing	_	_	_	_
28	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	basal	_	ADJ	_	Degree=Pos	_	_	_	_
6	redox	_	NOUN	_	Number=Sing	_	_	_	_
7	equilibrium	_	NOUN	_	Number=Sing	_	_	_	_
8	tending	_	VERB	_	VerbForm=Ger	_	_	_	_
9	toward	_	ADP	_	_	_	_	_	_
10	oxidation	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	prerequisite	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	full	_	ADJ	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	transduction	_	NOUN	_	Number=Sing	_	_	_	_
19	pathways	_	NOUN	_	Number=Plur	_	_	_	_
20	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001795	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p50	_	NOUN	_	Number=Sing	_	_	_	_
5	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	freshly	_	ADV	_	_	_	_	_	_
8	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	decreases	_	VERB	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vitro	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	vivo	_	ADJ	_	Number=Sing	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	possible	_	ADJ	_	Degree=Pos	_	_	_	_
22	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
23	influencing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
26	virus	_	NOUN	_	Number=Sing	_	_	_	_
27	replication	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	mature	_	ADJ	_	Degree=Pos	_	_	_	_
32	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	replicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	more	_	ADV	_	_	_	_	_	_
13	efficiently	_	ADV	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	vitro	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	differentiated	_	ADJ	_	Degree=Pos	_	_	_	_
18	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
19	than	_	ADP	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	freshly	_	ADV	_	_	_	_	_	_
22	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
5	may	_	AUX	_	VerbForm=Fin	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	partly	_	ADV	_	_	_	_	_	_
8	explained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	changes	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	primary	_	ADJ	_	Degree=Pos	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	changed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	significantly	_	ADV	_	_	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	vitro	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	monocyte	_	VERB	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	MDMs	_	NOUN	_	Number=Plur	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	vivo	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	alveolar	_	VERB	_	Degree=Pos	_	_	_	_
34	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	AMs	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Freshly	_	ADV	_	_	_	_	_	_
2	isolated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	constitutively	_	ADV	_	_	_	_	_	_
5	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	high	_	ADJ	_	Degree=Pos	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	transcriptionally	_	ADV	_	_	_	_	_	_
10	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
11	p50	_	NOUN	_	Number=Sing	_	_	_	_
12	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	time	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	culture	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	favor	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transcriptionally	_	ADV	_	_	_	_	_	_
24	active	_	ADJ	_	Degree=Pos	_	_	_	_
25	p50/p65	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	p50/RelB	_	NOUN	_	Number=Sing	_	_	_	_
28	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	MDMs	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	AMs	_	PROPN	_	Number=Sing	_	_	_	_
6	constitutively	_	ADV	_	_	_	_	_	_
7	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	p50/p65	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	p50/RelB	_	NOUN	_	Number=Sing	_	_	_	_
11	although	_	SCONJ	_	_	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	ADJ	_	Number=Sing	_	_	_	_
2	infection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	fresh	_	ADJ	_	Degree=Pos	_	_	_	_
5	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
9	p50/p65	_	NOUN	_	Number=Sing	_	_	_	_
10	as	_	SCONJ	_	_	_	_	_	_
11	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	MDMs	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	replacement	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p50	_	NOUN	_	Number=Sing	_	_	_	_
5	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	transcriptionally	_	ADV	_	_	_	_	_	_
8	active	_	ADJ	_	Degree=Pos	_	_	_	_
9	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
10	following	_	VERB	_	VerbForm=Ger	_	_	_	_
11	time	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	culture	_	NOUN	_	Number=Sing	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	partially	_	ADV	_	_	_	_	_	_
16	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	progressive	_	ADJ	_	Degree=Pos	_	_	_	_
19	increase	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	susceptibility	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	HIV	_	VERB	_	Number=Sing	_	_	_	_
26	infection	_	NOUN	_	Number=Sing	_	_	_	_
27	during	_	ADP	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	vitro	_	ADJ	_	Degree=Pos	_	_	_	_
30	culture	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	change	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	components	_	NOUN	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	vivo	_	NOUN	_	Number=Sing	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	different	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
19	activities	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	populations	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	individuals	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001801	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	element	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	zinc	_	NOUN	_	Number=Sing	_	_	_	_
18	finger	_	NOUN	_	Number=Sing	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	EGR	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
14	recognition	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	critical	_	ADJ	_	Degree=Pos	_	_	_	_
18	event	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	effector	_	NOUN	_	Number=Sing	_	_	_	_
25	function	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Prior	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	several	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	contribute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	novel	_	NOUN	_	Number=Sing	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	within	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	immediately	_	ADV	_	_	_	_	_	_
16	upstream	_	ADV	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	T	_	PROPN	_	Number=Sing	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	domain	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	zinc	_	NOUN	_	Number=Sing	_	_	_	_
7	finger	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	region	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	ZIP	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	serves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	binding	_	NOUN	_	Degree=Pos	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	two	_	NUM	_	NumType=Card	_	_	_	_
21	differently	_	ADV	_	_	_	_	_	_
22	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	zinc	_	NOUN	_	Number=Sing	_	_	_	_
24	finger	_	NOUN	_	Number=Sing	_	_	_	_
25	proteins	_	NOUN	_	Number=Plur	_	_	_	_
26	:	_	PUNCT	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	constitutively	_	ADV	_	_	_	_	_	_
29	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
36	early	_	ADJ	_	Degree=Pos	_	_	_	_
37	growth	_	NOUN	_	Number=Sing	_	_	_	_
38	response	_	NOUN	_	Number=Sing	_	_	_	_
39	protein	_	NOUN	_	Number=Sing	_	_	_	_
40	EGR	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	secrete	_	VERB	_	VerbForm=Inf	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	only	_	ADV	_	_	_	_	_	_
13	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
14	binds	_	NOUN	_	Number=Plur	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	region	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	while	_	SCONJ	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	secreting	_	VERB	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
29	EGR	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	protein	_	NOUN	_	Number=Sing	_	_	_	_
33	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
35	element	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	ZIP	_	NOUN	_	Number=Sing	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	serves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	activator	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	combination	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	ZIP	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	NFAT	_	NOUN	_	Degree=Pos	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	sites	_	NOUN	_	Number=Plur	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	activity	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	critical	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	ZIP	_	NOUN	_	Number=Sing	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001809	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Involvement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Alu	_	PROPN	_	Number=Sing	_	_	_	_
4	sequences	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	gamma	_	NOUN	_	Number=Sing	_	_	_	_
16	chain	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	Fc	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	receptors	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Fc	_	PROPN	_	Number=Sing	_	_	_	_
3	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
4	RI	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	gamma	_	NOUN	_	Number=Sing	_	_	_	_
7	chains	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	variety	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	where	_	ADV	_	PronType=Rel	_	_	_	_
17	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
18	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	critical	_	ADJ	_	Degree=Pos	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	signal	_	ADJ	_	Number=Sing	_	_	_	_
24	transduction	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	part	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	high	_	ADJ	_	Degree=Pos	_	_	_	_
7	affinity	_	NOUN	_	Number=Sing	_	_	_	_
8	IgE	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	mast	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	basophils	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	Langerhans	_	ADJ	_	Number=Plur	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	possibly	_	ADV	_	_	_	_	_	_
21	other	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	;	_	PUNCT	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	component	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	low	_	ADJ	_	Degree=Pos	_	_	_	_
29	affinity	_	NOUN	_	Number=Sing	_	_	_	_
30	receptor	_	NOUN	_	Number=Sing	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	IgG	_	PROPN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	Fc	_	PROPN	_	Number=Sing	_	_	_	_
35	gamma	_	NOUN	_	Number=Sing	_	_	_	_
36	RIIIA	_	PROPN	_	Number=Sing	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	CD16	_	PROPN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	natural	_	ADJ	_	Degree=Pos	_	_	_	_
42	killer	_	NOUN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
46	;	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	part	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	T	_	NOUN	_	Number=Sing	_	_	_	_
52	cell	_	NOUN	_	Number=Sing	_	_	_	_
53	antigen	_	NOUN	_	Number=Sing	_	_	_	_
54	receptor	_	NOUN	_	Number=Sing	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	subsets	_	NOUN	_	Number=Plur	_	_	_	_
57	of	_	ADP	_	_	_	_	_	_
58	T	_	NOUN	_	Number=Sing	_	_	_	_
59	cells	_	NOUN	_	Number=Plur	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	gamma	_	NOUN	_	Number=Sing	_	_	_	_
11	chain	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	analyzing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	2.5	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kilobase	_	NOUN	_	Number=Sing	_	_	_	_
19	sequence	_	NOUN	_	Number=Sing	_	_	_	_
20	upstream	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	start	_	NOUN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
11	lineage	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	tissue	_	NOUN	_	Number=Sing	_	_	_	_
5	specificity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	only	_	ADV	_	_	_	_	_	_
11	partial	_	ADJ	_	Degree=Pos	_	_	_	_
12	because	_	SCONJ	_	_	_	_	_	_
13	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	active	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	all	_	DET	_	_	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	here	_	ADV	_	PronType=Dem	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	regardless	_	ADV	_	_	_	_	_	_
26	of	_	SCONJ	_	_	_	_	_	_
27	whether	_	SCONJ	_	_	_	_	_	_
28	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
29	constitutively	_	ADV	_	_	_	_	_	_
30	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	Fc	_	PROPN	_	Number=Sing	_	_	_	_
32	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
33	RI	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	gamma	_	NOUN	_	Number=Sing	_	_	_	_
36	chain	_	NOUN	_	Number=Sing	_	_	_	_
37	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
6	cis	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
9	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	elements	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Int	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	part	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	Alu	_	PROPN	_	Number=Sing	_	_	_	_
20	repeat	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	-	_	SYM	_	_	_	_	_	_
5	445/-366	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	positive	_	ADJ	_	Degree=Pos	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	active	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	basophils	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	second	_	NOUN	_	Degree=Pos|NumType=Ord	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	365/-264	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	different	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	basophils	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	acts	_	VERB	_	Number=Plur	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	negative	_	ADJ	_	Degree=Pos	_	_	_	_
28	element	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	basophils	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	positive	_	ADJ	_	Degree=Pos	_	_	_	_
35	one	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	T	_	PROPN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	Alu	_	PROPN	_	Number=Sing	_	_	_	_
5	repeat	_	VERB	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	90	_	NUM	_	NumType=Card	_	_	_	_
8	%	_	SYM	_	Number=Sing	_	_	_	_
9	identical	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	Alu	_	ADJ	_	Number=Sing	_	_	_	_
12	consensus	_	NOUN	_	Number=Sing	_	_	_	_
13	sequences	_	NOUN	_	Number=Plur	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	evolved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	become	_	VERB	_	VerbForm=Inf	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	positive	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	negative	_	ADJ	_	Degree=Pos	_	_	_	_
24	regulator	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001811	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	autoregulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	lines	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	GR	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	cognate	_	ADJ	_	Number=Sing	_	_	_	_
12	ligand	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	leukemic	_	NOUN	_	Number=Sing	_	_	_	_
22	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	6TG1.1	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	line	_	NOUN	_	Number=Sing	_	_	_	_
33	IM	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	9	_	NUM	_	NumType=Card	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	decrease	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	GR	_	PROPN	_	Number=Sing	_	_	_	_
8	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
9	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	IM	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	9	_	NUM	_	NumType=Card	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	after	_	ADP	_	_	_	_	_	_
16	treatment	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	microM	_	NOUN	_	Number=Sing	_	_	_	_
20	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	16	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	18	_	NUM	_	NumType=Card	_	_	_	_
25	h	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	treatment	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	6TG1	_	NUM	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	8	_	NUM	_	NumType=Card	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	fold	_	NOUN	_	Number=Sing	_	_	_	_
39	increase	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	GR	_	PROPN	_	Number=Sing	_	_	_	_
42	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	as	_	SCONJ	_	_	_	_	_	_
45	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	by	_	ADP	_	_	_	_	_	_
47	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
48	blot	_	PROPN	_	Number=Sing	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	RNase	_	PROPN	_	Number=Sing	_	_	_	_
51	protection	_	NOUN	_	Number=Sing	_	_	_	_
52	analysis	_	NOUN	_	Number=Sing	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	with	_	ADP	_	_	_	_	_	_
55	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
56	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
57	3	_	NUM	_	NumType=Card	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	to	_	ADP	_	_	_	_	_	_
60	4	_	NUM	_	NumType=Card	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	fold	_	NOUN	_	Number=Sing	_	_	_	_
63	increase	_	NOUN	_	Number=Sing	_	_	_	_
64	in	_	ADP	_	_	_	_	_	_
65	GR	_	NOUN	_	Number=Sing	_	_	_	_
66	protein	_	NOUN	_	Number=Sing	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	Half	_	ADJ	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	GR	_	NOUN	_	Number=Sing	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	6TG1.1	_	NUM	_	NumType=Card	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	between	_	ADP	_	_	_	_	_	_
16	10	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	100	_	NUM	_	NumType=Card	_	_	_	_
19	nM	_	NUM	_	Number=Sing	_	_	_	_
20	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	inclusion	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	microM	_	NOUN	_	Number=Sing	_	_	_	_
27	RU	_	PROPN	_	Number=Sing	_	_	_	_
28	38486	_	NUM	_	NumType=Card	_	_	_	_
29	completely	_	ADV	_	_	_	_	_	_
30	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	effects	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	100	_	NUM	_	NumType=Card	_	_	_	_
35	nM	_	NOUN	_	Number=Sing	_	_	_	_
36	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
39	that	_	SCONJ	_	_	_	_	_	_
40	positive	_	ADJ	_	Degree=Pos	_	_	_	_
41	autoregulation	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	GR	_	NOUN	_	Number=Sing	_	_	_	_
44	expression	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	6TG1.1	_	NUM	_	NumType=Card	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
50	receptor	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	mediated	_	VERB	_	Degree=Pos	_	_	_	_
53	response	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Positive	_	ADJ	_	Degree=Pos	_	_	_	_
2	autoregulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	GR	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
13	CEM	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	C1	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	functional	_	ADJ	_	Degree=Pos	_	_	_	_
21	GR	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
25	growth	_	NOUN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	positive	_	ADJ	_	Degree=Pos	_	_	_	_
4	autoregulation	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	neither	_	CCONJ	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	consequence	_	NOUN	_	Number=Sing	_	_	_	_
9	nor	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	sole	_	ADJ	_	Degree=Pos	_	_	_	_
12	cause	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	growth	_	NOUN	_	Number=Sing	_	_	_	_
15	arrest	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	degree	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	negative	_	ADJ	_	Degree=Pos	_	_	_	_
5	autoregulation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	IM	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	9	_	NUM	_	NumType=Card	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	positive	_	ADJ	_	Degree=Pos	_	_	_	_
13	autoregulation	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	6TG1.1	_	NUM	_	NumType=Card	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	unaffected	_	VERB	_	Degree=Pos	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Measurement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	GR	_	NOUN	_	Number=Sing	_	_	_	_
4	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
5	turnover	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	6TG1.1	_	NUM	_	NumType=Card	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	actinomycin	_	NOUN	_	Number=Sing	_	_	_	_
12	-D	_	PROPN	_	Number=Sing	_	_	_	_
13	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	half	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	life	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	2.5	_	NUM	_	NumType=Card	_	_	_	_
20	h	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	unaffected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
27	treatment	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	similar	_	ADJ	_	Degree=Pos	_	_	_	_
3	half	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	life	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	IM	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	9	_	NUM	_	NumType=Card	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	unaffected	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	interpretation	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
12	autoregulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	GR	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	tissue	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	primary	_	ADJ	_	Degree=Pos	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001815	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Fcgamma	_	PROPN	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
5	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	independent	_	ADJ	_	Degree=Pos	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	Ras	_	PROPN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Receptors	_	NOUN	_	Number=Plur	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	Fc	_	PROPN	_	Number=Sing	_	_	_	_
5	portion	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
8	molecules	_	NOUN	_	Number=Plur	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	FcR	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	present	_	ADJ	_	Degree=Pos	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	leukocyte	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	membranes	_	NOUN	_	Number=Plur	_	_	_	_
17	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	large	_	ADJ	_	Degree=Pos	_	_	_	_
20	number	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
23	responses	_	NOUN	_	Number=Plur	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	very	_	ADV	_	_	_	_	_	_
27	important	_	ADJ	_	Degree=Pos	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	host	_	NOUN	_	Number=Sing	_	_	_	_
30	defense	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	including	_	VERB	_	VerbForm=Ger	_	_	_	_
33	phagocytosis	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	production	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	secretion	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
43	mediators	_	NOUN	_	Number=Plur	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	modulation	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	immune	_	ADJ	_	Degree=Pos	_	_	_	_
50	response	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Cross	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	linking	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	FcR	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	immune	_	ADJ	_	Number=Sing	_	_	_	_
8	complexes	_	NOUN	_	Number=Plur	_	_	_	_
9	leads	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	first	_	ADV	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
18	kinases	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	events	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	follow	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	that	_	DET	_	_	_	_	_	_
8	transduce	_	NOUN	_	Number=Sing	_	_	_	_
9	signals	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	receptors	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	still	_	ADV	_	_	_	_	_	_
18	poorly	_	ADV	_	_	_	_	_	_
19	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	signal	_	NOUN	_	Number=Sing	_	_	_	_
6	transduction	_	NOUN	_	Number=Sing	_	_	_	_
7	pathway	_	NOUN	_	Number=Sing	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	Fc	_	PROPN	_	Number=Sing	_	_	_	_
10	receptors	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	gene	_	NOUN	_	VerbForm=Inf	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Cross	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	linking	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	FcR	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	THP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	line	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	immune	_	ADJ	_	Number=Sing	_	_	_	_
18	complexes	_	NOUN	_	Number=Plur	_	_	_	_
19	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	both	_	DET	_	_	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	production	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	responses	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	completely	_	ADV	_	_	_	_	_	_
5	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
7	negative	_	ADJ	_	Degree=Pos	_	_	_	_
8	mutants	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Ras	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Raf	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	have	_	VERB	_	VerbForm=Inf	_	_	_	_
23	any	_	DET	_	_	_	_	_	_
24	effect	_	NOUN	_	Number=Sing	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	FcR	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
34	that	_	SCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	protein	_	NOUN	_	Number=Sing	_	_	_	_
40	kinase	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	signaling	_	NOUN	_	Number=Sing	_	_	_	_
45	pathway	_	NOUN	_	Number=Sing	_	_	_	_
46	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
47	not	_	PART	_	_	_	_	_	_
48	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
49	by	_	ADP	_	_	_	_	_	_
50	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
51	receptors	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	easily	_	ADV	_	_	_	_	_	_
7	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vitro	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	assays	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	after	_	ADP	_	_	_	_	_	_
15	FcR	_	PROPN	_	Number=Sing	_	_	_	_
16	cross	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	immune	_	ADJ	_	Number=Sing	_	_	_	_
21	complexes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	signal	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	kinase	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
14	kinase	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
17	PD98059	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	FcR	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
34	factor	_	NOUN	_	Number=Sing	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	strongly	_	ADV	_	_	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	signaling	_	NOUN	_	Number=Sing	_	_	_	_
8	pathway	_	NOUN	_	Number=Sing	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	Fc	_	PROPN	_	Number=Sing	_	_	_	_
11	receptors	_	NOUN	_	Number=Plur	_	_	_	_
12	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	different	_	ADJ	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	important	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	leukocyte	_	VERB	_	VerbForm=Inf	_	_	_	_
21	biology	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	initiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
26	kinases	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	;	_	PUNCT	_	_	_	_	_	_
32	but	_	CCONJ	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	contrast	_	NOUN	_	Number=Sing	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	other	_	ADJ	_	Degree=Pos	_	_	_	_
37	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
38	kinase	_	NOUN	_	Number=Sing	_	_	_	_
39	receptors	_	NOUN	_	Number=Plur	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	FcR	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
44	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
47	not	_	PART	_	_	_	_	_	_
48	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
49	Ras	_	PROPN	_	Number=Sing	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	Raf	_	PROPN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001817	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	NOUN	_	Number=Sing	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	T-lineage	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
16	decrease	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
22	production	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	response	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
32	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	not	_	ADV	_	_	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	abnormal	_	VERB	_	Degree=Pos	_	_	_	_
38	thymopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	complexes	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	development	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
22	mice	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	RelA	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
28	complexes	_	NOUN	_	Number=Plur	_	_	_	_
29	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	selectively	_	ADV	_	_	_	_	_	_
31	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	T-lineage	_	PROPN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	specific	_	ADJ	_	Degree=Pos	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	trans	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
44	form	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
47	kappa	_	PROPN	_	Number=Sing	_	_	_	_
48	B	_	PROPN	_	Number=Sing	_	_	_	_
49	alpha	_	PROPN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Transgene	_	ADJ	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
8	development	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	lowered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	numbers	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	splenic	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
23	decrease	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	ex	_	X	_	Number=Sing	_	_	_	_
27	vivo	_	X	_	Number=Sing	_	_	_	_
28	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
29	response	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	splenic	_	ADJ	_	Degree=Pos	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2R	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	perturbation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	attributable	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	genes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	10	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	IFN	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	gamma	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	strongly	_	ADV	_	_	_	_	_	_
20	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
3	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	point	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	out	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	involvement	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	Rel	_	PROPN	_	Number=Sing	_	_	_	_
14	family	_	NOUN	_	Number=Sing	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	growth	_	NOUN	_	Number=Sing	_	_	_	_
18	signaling	_	NOUN	_	Number=Sing	_	_	_	_
19	pathways	_	NOUN	_	Number=Plur	_	_	_	_
20	by	_	SCONJ	_	_	_	_	_	_
21	either	_	CCONJ	_	_	_	_	_	_
22	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	signaling	_	NOUN	_	Number=Sing	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	by	_	SCONJ	_	_	_	_	_	_
33	functionally	_	ADV	_	_	_	_	_	_
34	interfering	_	VERB	_	VerbForm=Ger	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	cycle	_	NOUN	_	Number=Sing	_	_	_	_
39	progression	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001820	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Pentoxifylline	_	NOUN	_	Number=Sing	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	infection	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Cytokine	_	PROPN	_	Number=Sing	_	_	_	_
2	dysregulation	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	infection	_	NOUN	_	Number=Sing	_	_	_	_
15	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	documented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	numerous	_	ADJ	_	Degree=Pos	_	_	_	_
20	studies	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	cited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	important	_	ADJ	_	Degree=Pos	_	_	_	_
28	component	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
34	retroviral	_	ADJ	_	Degree=Pos	_	_	_	_
35	infection	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Pharmacological	_	ADJ	_	Degree=Pos	_	_	_	_
2	modification	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
5	dysregulation	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	therefore	_	ADV	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
15	modality	_	NOUN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	infection	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Dr.	_	PROPN	_	Number=Sing	_	_	_	_
2	Dezube	_	PROPN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Beth	_	PROPN	_	Number=Sing	_	_	_	_
5	Israel	_	PROPN	_	Number=Sing	_	_	_	_
6	Hospital	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	Boston	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	concisely	_	ADV	_	_	_	_	_	_
11	reviews	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	state	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
16	knowledge	_	NOUN	_	Number=Sing	_	_	_	_
17	regarding	_	VERB	_	VerbForm=Ger	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	effects	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	pentoxifylline	_	NOUN	_	Number=Sing	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	tumor	_	NOUN	_	Number=Sing	_	_	_	_
26	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
33	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
36	HIV	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	replication	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	to	_	PART	_	_	_	_	_	_
42	play	_	VERB	_	VerbForm=Inf	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	possible	_	ADJ	_	Degree=Pos	_	_	_	_
45	role	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
49	manifestations	_	NOUN	_	Number=Plur	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	advanced	_	ADJ	_	Degree=Pos	_	_	_	_
52	infection	_	NOUN	_	Number=Sing	_	_	_	_
53	with	_	ADP	_	_	_	_	_	_
54	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
55	virus	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Pentoxifylline	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	trisubstituted	_	ADJ	_	Degree=Pos	_	_	_	_
5	xanthine	_	NOUN	_	Number=Sing	_	_	_	_
6	derivative	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	decrease	_	VERB	_	VerbForm=Inf	_	_	_	_
13	blood	_	NOUN	_	Number=Sing	_	_	_	_
14	viscosity	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	reasonably	_	ADV	_	_	_	_	_	_
18	well	_	ADV	_	Degree=Pos	_	_	_	_
19	tolerated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	most	_	ADJ	_	Degree=Sup	_	_	_	_
22	recipients	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	drug	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Results	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	preliminary	_	ADJ	_	Degree=Pos	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	many	_	ADJ	_	Degree=Pos	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	conducted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	Dr.	_	PROPN	_	Number=Sing	_	_	_	_
13	Dezube	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
17	use	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	agent	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	combination	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	antiretroviral	_	ADJ	_	Degree=Pos	_	_	_	_
25	compounds	_	NOUN	_	Number=Plur	_	_	_	_
26	may	_	AUX	_	VerbForm=Fin	_	_	_	_
27	prove	_	VERB	_	VerbForm=Inf	_	_	_	_
28	useful	_	ADJ	_	Degree=Pos	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	treatment	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	patients	_	NOUN	_	Number=Plur	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	HIV	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	infection	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001826	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	binding	_	VERB	_	Number=Sing	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Barr	_	PROPN	_	Number=Sing	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	antigen	_	NOUN	_	Number=Sing	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	evidence	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	complex	_	ADJ	_	Degree=Pos	_	_	_	_
23	formation	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	latent	_	ADJ	_	Degree=Pos	_	_	_	_
26	membrane	_	NOUN	_	Number=Sing	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	binding	_	VERB	_	Number=Sing	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	positive	_	ADJ	_	Degree=Pos	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	lines	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Barr	_	PROPN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	EBV	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	antigen	_	NOUN	_	Number=Sing	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	X	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	essential	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	primary	_	ADJ	_	Degree=Pos	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	EBV	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	trans	_	NOUN	_	Number=Plur	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	viral	_	ADJ	_	Degree=Pos	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	like	_	ADP	_	_	_	_	_	_
12	CD23	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	c-fgr	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	latent	_	ADJ	_	Degree=Pos	_	_	_	_
17	membrane	_	NOUN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	terminal	_	NOUN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	TP1	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Trans	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	TP1	_	NOUN	_	Number=Sing	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	BamHI	_	PROPN	_	Number=Sing	_	_	_	_
12	C	_	PROPN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	already	_	ADV	_	_	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	detail	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	via	_	ADP	_	_	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	interactions	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	not	_	PART	_	_	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	direct	_	ADJ	_	Degree=Pos	_	_	_	_
34	binding	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	type	_	NOUN	_	Number=Sing	_	_	_	_
40	A	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	EBV	_	NOUN	_	Number=Sing	_	_	_	_
44	type	_	NOUN	_	Number=Sing	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	to	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	DNA	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	able	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	trans	_	VERB	_	VerbForm=Inf	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	LMP	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	several	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Various	_	ADJ	_	Degree=Pos	_	_	_	_
2	reports	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	delineated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	cis	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
9	elements	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	LMP	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	mediates	_	NOUN	_	Number=Plur	_	_	_	_
20	trans	_	NOUN	_	Number=Plur	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	trans	_	NOUN	_	Number=Plur	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	LMP	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	interactions	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
21	performed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	series	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	gel	_	NOUN	_	Number=Sing	_	_	_	_
26	retardation	_	NOUN	_	Number=Sing	_	_	_	_
27	assays	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	competition	_	NOUN	_	Number=Sing	_	_	_	_
30	experiments	_	NOUN	_	Number=Plur	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	LMP	_	NOUN	_	Number=Sing	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	fragments	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	different	_	ADJ	_	Degree=Pos	_	_	_	_
37	sizes	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	determined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	region	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	LMP	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	within	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	42	_	NUM	_	NumType=Card	_	_	_	_
17	bp	_	PROPN	_	Number=Sing	_	_	_	_
18	fragment	_	NOUN	_	Number=Sing	_	_	_	_
19	encompassing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	135	_	NUM	_	NumType=Card	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	-	_	SYM	_	_	_	_	_	_
25	176	_	NUM	_	NumType=Card	_	_	_	_
26	relative	_	ADV	_	_	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	LMP	_	NOUN	_	Number=Sing	_	_	_	_
30	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
31	start	_	NOUN	_	Number=Sing	_	_	_	_
32	site	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	None	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	fragments	_	NOUN	_	Number=Plur	_	_	_	_
6	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	indicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	interaction	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	DNA	_	NOUN	_	Number=Sing	_	_	_	_
16	via	_	ADP	_	_	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	interactions	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	significant	_	ADJ	_	Degree=Pos	_	_	_	_
3	differences	_	NOUN	_	Number=Plur	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	positive	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	negative	_	ADJ	_	Degree=Pos	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	extracts	_	NOUN	_	Number=Plur	_	_	_	_
18	could	_	AUX	_	VerbForm=Fin	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	gel	_	NOUN	_	Number=Sing	_	_	_	_
24	retardation	_	NOUN	_	Number=Sing	_	_	_	_
25	assay	_	NOUN	_	Number=Sing	_	_	_	_
26	under	_	ADP	_	_	_	_	_	_
27	conditions	_	NOUN	_	Number=Plur	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	clearly	_	ADV	_	_	_	_	_	_
30	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	binding	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2A	_	NOUN	_	Number=Sing	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	TP1	_	NOUN	_	Number=Sing	_	_	_	_
39	promoter	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	sucrose	_	ADJ	_	Number=Sing	_	_	_	_
6	gradient	_	NOUN	_	Number=Sing	_	_	_	_
7	fractions	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	gel	_	NOUN	_	Number=Sing	_	_	_	_
11	retardation	_	NOUN	_	Number=Sing	_	_	_	_
12	assay	_	NOUN	_	Number=Sing	_	_	_	_
13	provided	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	evidence	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	LMP	_	NOUN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	form	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	complex	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
27	M	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	r	_	X	_	_	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	positive	_	ADJ	_	Degree=Pos	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	extracts	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	complexes	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	destroyed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	detergent	_	NOUN	_	Number=Sing	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	deduce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	positive	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	might	_	AUX	_	VerbForm=Fin	_	_	_	_
14	indeed	_	ADV	_	_	_	_	_	_
15	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	complexes	_	NOUN	_	Number=Plur	_	_	_	_
18	bound	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	LMP	_	NOUN	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	however	_	ADV	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	too	_	ADV	_	_	_	_	_	_
29	labile	_	ADJ	_	Degree=Pos	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	be	_	AUX	_	VerbForm=Inf	_	_	_	_
32	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	standard	_	ADJ	_	Degree=Pos	_	_	_	_
36	gel	_	NOUN	_	Number=Sing	_	_	_	_
37	retardation	_	NOUN	_	Number=Sing	_	_	_	_
38	assay	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001831	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Immunosuppressant	_	PROPN	_	Degree=Pos	_	_	_	_
2	PG490	_	PROPN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	triptolide	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	level	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	purine	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	box	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	NF	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
29	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	PG490	_	NOUN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	triptolide	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	diterpene	_	NOUN	_	Number=Sing	_	_	_	_
8	triepoxide	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	potent	_	ADJ	_	Degree=Pos	_	_	_	_
11	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	antiinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	properties	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	PG490	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
3	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	normal	_	ADJ	_	Degree=Pos	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
14	blood	_	NOUN	_	Number=Sing	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
19	12	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	myristate	_	NOUN	_	Number=Sing	_	_	_	_
22	13	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	acetate	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	PMA	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	antibody	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	CD3	_	PROPN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	IC50	_	PROPN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	10	_	NUM	_	NumType=Card	_	_	_	_
36	ng	_	NOUN	_	Number=Sing	_	_	_	_
37	/	_	SYM	_	_	_	_	_	_
38	ml	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	with	_	ADP	_	_	_	_	_	_
43	PMA	_	NOUN	_	Number=Sing	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	ionomycin	_	PROPN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	Iono	_	PROPN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	IC50	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	40	_	NUM	_	NumType=Card	_	_	_	_
52	ng	_	NOUN	_	Number=Sing	_	_	_	_
53	/	_	SYM	_	_	_	_	_	_
54	ml	_	NOUN	_	Number=Sing	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
3	T-cells	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	PG490	_	PROPN	_	Number=Sing	_	_	_	_
6	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	PMA	_	PROPN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	Iono	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	PG490	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	DNA	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	purine	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	box	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	antigen	_	NOUN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	element	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	ARRE	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	AT	_	ADP	_	_	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	target	_	NOUN	_	Number=Sing	_	_	_	_
34	sequence	_	NOUN	_	Number=Sing	_	_	_	_
35	but	_	CCONJ	_	_	_	_	_	_
36	not	_	PART	_	_	_	_	_	_
37	at	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
42	site	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	PG490	_	NOUN	_	Number=Sing	_	_	_	_
2	can	_	AUX	_	VerbForm=Fin	_	_	_	_
3	completely	_	ADV	_	_	_	_	_	_
4	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	at	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	purine	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	box	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	ARRE	_	PROPN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	NF-AT	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	target	_	NOUN	_	Number=Sing	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	sequences	_	NOUN	_	Number=Plur	_	_	_	_
23	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	all	_	DET	_	_	_	_	_	_
26	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
27	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	PMA	_	PROPN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	PMA	_	PROPN	_	Number=Sing	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	Iono	_	PROPN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	tumor	_	NOUN	_	Number=Sing	_	_	_	_
36	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
37	factor	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	alpha	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	PG490	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	PMA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	chimeric	_	ADJ	_	Degree=Pos	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	C	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	terminal	_	NOUN	_	Number=Sing	_	_	_	_
19	TA1	_	NOUN	_	Number=Sing	_	_	_	_
20	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
21	domain	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
26	p65	_	NOUN	_	Number=Sing	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	fused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	DNA	_	PROPN	_	Number=Sing	_	_	_	_
32	binding	_	VERB	_	Number=Sing	_	_	_	_
33	domain	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	GAL4	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	16HBE	_	NUM	_	NumType=Card	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	bronchial	_	ADJ	_	Degree=Pos	_	_	_	_
5	epithelial	_	NOUN	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	8	_	NUM	_	NumType=Card	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	predominantly	_	ADV	_	_	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	PG490	_	PROPN	_	Number=Sing	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	not	_	ADV	_	_	_	_	_	_
24	cyclosporin	_	VERB	_	Number=Sing	_	_	_	_
25	A	_	NOUN	_	Number=Sing	_	_	_	_
26	can	_	AUX	_	VerbForm=Fin	_	_	_	_
27	completely	_	ADV	_	_	_	_	_	_
28	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	8	_	NUM	_	NumType=Card	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	PG490	_	PROPN	_	Number=Sing	_	_	_	_
5	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cytokine	_	ADJ	_	Degree=Pos	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	differs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
13	A	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	purine	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	box	_	NOUN	_	Number=Sing	_	_	_	_
30	regulator	_	NOUN	_	Number=Sing	_	_	_	_
31	operating	_	VERB	_	VerbForm=Ger	_	_	_	_
32	at	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	ARRE	_	PROPN	_	Number=Sing	_	_	_	_
35	/	_	PUNCT	_	_	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	AT	_	ADP	_	_	_	_	_	_
39	site	_	NOUN	_	Number=Sing	_	_	_	_
40	at	_	ADP	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	step	_	NOUN	_	Number=Sing	_	_	_	_
43	after	_	ADP	_	_	_	_	_	_
44	specific	_	ADJ	_	Degree=Pos	_	_	_	_
45	DNA	_	PROPN	_	Number=Sing	_	_	_	_
46	binding	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001835	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	functions	_	NOUN	_	Number=Plur	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	proapoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	antiapoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	within	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	single	_	ADJ	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	have	_	VERB	_	VerbForm=Inf	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	proapoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	antiapoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
14	functions	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	T	_	NUM	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	hybridomas	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	T	_	NUM	_	NumType=Card	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	activators	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
12	induce	_	VERB	_	Number=Sing	_	_	_	_
13	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	blockade	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	using	_	VERB	_	VerbForm=Ger	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
15	negative	_	ADJ	_	Degree=Pos	_	_	_	_
16	IkappaBalpha	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	opposite	_	ADJ	_	Degree=Pos	_	_	_	_
20	effects	_	NOUN	_	Number=Plur	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
23	two	_	NUM	_	NumType=Card	_	_	_	_
24	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
25	signals	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	PMA	_	PROPN	_	Number=Sing	_	_	_	_
4	plus	_	CCONJ	_	_	_	_	_	_
5	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	P	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	I	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	results	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	Fas	_	PROPN	_	Number=Sing	_	_	_	_
17	Ligand	_	PROPN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	FasL	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	induction	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	P	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	mediated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	FasL	_	ADJ	_	Degree=Pos	_	_	_	_
16	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	decreases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
25	cultures	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	thus	_	ADV	_	_	_	_	_	_
28	establishing	_	VERB	_	VerbForm=Ger	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	proapoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
38	context	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Conversely	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	tenfold	_	NOUN	_	Number=Sing	_	_	_	_
11	increase	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
14	mediated	_	VERB	_	Degree=Pos	_	_	_	_
15	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	establishing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	also	_	ADV	_	_	_	_	_	_
23	functions	_	NOUN	_	Number=Plur	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	antiapoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	context	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
13	regulator	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	function	_	VERB	_	VerbForm=Inf	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	antiapoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	while	_	SCONJ	_	_	_	_	_	_
17	functioning	_	VERB	_	VerbForm=Ger	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	proapoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	mature	_	ADJ	_	Degree=Pos	_	_	_	_
24	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001837	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Immune	_	ADJ	_	Degree=Pos	_	_	_	_
2	hyperactivation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1-infected	_	ADJ	_	Degree=Pos	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	Tat	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	CD28	_	NOUN	_	Number=Sing	_	_	_	_
15	pathway	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	infection	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
18	state	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	immune	_	ADJ	_	Degree=Pos	_	_	_	_
21	hyperactivation	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	patients	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Infection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
5	blood	_	NOUN	_	Number=Sing	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	vitro	_	NOUN	_	Number=Sing	_	_	_	_
13	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	secretion	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	response	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	via	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	CD3	_	PROPN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	CD28	_	PROPN	_	Number=Sing	_	_	_	_
36	receptors	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	transactivator	_	NOUN	_	Number=Sing	_	_	_	_

1	Tat	_	PROPN	_	Number=Sing	_	_	_	_
2	recapitulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	secretion	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	CD3	_	PROPN	_	Number=Sing	_	_	_	_
20	plus	_	CCONJ	_	_	_	_	_	_
21	CD28	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	superinduction	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	Tat	_	PROPN	_	Number=Sing	_	_	_	_
7	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	at	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	level	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	CD28	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
20	element	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	exclusively	_	ADV	_	_	_	_	_	_
31	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
32	on	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	29	_	NUM	_	NumType=Card	_	_	_	_
35	amino	_	ADJ	_	Number=Sing	_	_	_	_
36	acids	_	NOUN	_	Number=Plur	_	_	_	_
37	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
41	exon	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	Tat	_	PROPN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001844	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	attenuates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	apoptosis	_	ADJ	_	Number=Sing	_	_	_	_
9	resistance	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Death	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	ligands	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	DILs	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	such	_	ADJ	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	tumor	_	NOUN	_	Number=Sing	_	_	_	_
11	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
20	drug	_	NOUN	_	Number=Sing	_	_	_	_
21	doxorubicin	_	NOUN	_	Number=Sing	_	_	_	_
22	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
36	program	_	NOUN	_	Number=Sing	_	_	_	_
37	that	_	PRON	_	PronType=Rel	_	_	_	_
38	may	_	AUX	_	VerbForm=Fin	_	_	_	_
39	rescue	_	VERB	_	VerbForm=Inf	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	from	_	ADP	_	_	_	_	_	_
42	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
43	induction	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TRAIL	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	related	_	ADJ	_	Degree=Pos	_	_	_	_
10	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	ligand	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	recently	_	ADV	_	_	_	_	_	_
18	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	DIL	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	also	_	ADV	_	_	_	_	_	_
22	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	lines	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	kinetic	_	ADJ	_	Degree=Pos	_	_	_	_
31	similar	_	ADJ	_	Degree=Pos	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	independent	_	ADJ	_	Degree=Pos	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	FADD	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	caspases	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	apoptosis	_	ADJ	_	Number=Sing	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	study	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	influence	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	TRAIL	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	CD95	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	doxorubicin	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	NFkappaB	_	ADJ	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	using	_	VERB	_	VerbForm=Ger	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
28	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
29	N-acetyl-L-leucinyl-L-leucinyl-L-norleucinal	_	ADJ	_	Number=Sing	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	transient	_	ADJ	_	Degree=Pos	_	_	_	_
32	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	mutant	_	ADJ	_	Number=Sing	_	_	_	_
35	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	markedly	_	ADV	_	_	_	_	_	_
8	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	treatments	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	apoptosis	_	ADJ	_	Number=Sing	_	_	_	_
14	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	lines	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	both	_	CCONJ	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	lines	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
15	towards	_	ADP	_	_	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	DILs	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	doxorubicin	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	antagonization	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	partially	_	ADV	_	_	_	_	_	_
29	restored	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	apoptosis	_	ADJ	_	Degree=Pos	_	_	_	_
31	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	may	_	AUX	_	VerbForm=Fin	_	_	_	_
10	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
13	approach	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
16	apoptosis	_	ADJ	_	Degree=Pos	_	_	_	_
17	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	anticancer	_	NOUN	_	Number=Sing	_	_	_	_
20	treatment	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001845	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CD14	_	PROPN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	during	_	ADP	_	_	_	_	_	_
6	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
7	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	25	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
16	D3.	_	PROPN	_	Number=Sing	_	_	_	_
17	CD14	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	complex	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	LPS	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	LPS	_	NOUN	_	Number=Sing	_	_	_	_
31	binding	_	VERB	_	Number=Sing	_	_	_	_
32	protein	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
37	marker	_	NOUN	_	Number=Sing	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
41	/	_	PUNCT	_	_	_	_	_	_
42	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
43	lineage	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CD14	_	PROPN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	alpha,25	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
14	D3	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	FACS	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
5	blotting	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	run	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	analyses	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	up-regulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	CD14	_	PROPN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	during	_	ADP	_	_	_	_	_	_
23	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	maturation	_	NOUN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	mainly	_	ADV	_	_	_	_	_	_
29	at	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	level	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	that	_	SCONJ	_	_	_	_	_	_
38	new	_	ADJ	_	Degree=Pos	_	_	_	_
39	protein	_	NOUN	_	Number=Sing	_	_	_	_
40	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
41	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	for	_	ADP	_	_	_	_	_	_
44	CD14	_	PROPN	_	Number=Sing	_	_	_	_
45	induction	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	recently	_	ADV	_	_	_	_	_	_
4	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	CD14	_	PROPN	_	Number=Sing	_	_	_	_
7	5	_	NUM	_	NumType=Card	_	_	_	_
8	'	_	PUNCT	_	_	_	_	_	_
9	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
10	sequence	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	tissue	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	stable	_	ADJ	_	Degree=Pos	_	_	_	_
3	transfection	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	monocytoid	_	NOUN	_	Number=Sing	_	_	_	_
7	U937	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	line	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	series	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	deletion	_	NOUN	_	Number=Sing	_	_	_	_
15	mutants	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	CD14	_	PROPN	_	Number=Sing	_	_	_	_
19	5'	_	NUM	_	NumType=Card	_	_	_	_
20	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
21	sequence	_	NOUN	_	Number=Sing	_	_	_	_
22	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	reporter	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	construct	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
30	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	bp	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	128	_	NUM	_	NumType=Card	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	-	_	SYM	_	_	_	_	_	_
37	70	_	NUM	_	NumType=Card	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	critical	_	ADJ	_	Degree=Pos	_	_	_	_
41	region	_	NOUN	_	Number=Sing	_	_	_	_
42	for	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	induction	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	CD14	_	PROPN	_	Number=Sing	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	binding	_	NOUN	_	Degree=Pos	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	3	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	bp	_	NOUN	_	Number=Sing	_	_	_	_
5	mutation	_	NOUN	_	Number=Sing	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	distal	_	ADJ	_	Degree=Pos	_	_	_	_
9	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	only	_	ADV	_	_	_	_	_	_
15	eliminates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
17	interaction	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	also	_	ADV	_	_	_	_	_	_
21	abolishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	most	_	ADJ	_	Degree=Sup	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	VitD3	_	PROPN	_	Number=Sing	_	_	_	_
26	induction	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	CD14	_	PROPN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	detect	_	VERB	_	VerbForm=Inf	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	direct	_	ADJ	_	Degree=Pos	_	_	_	_
10	interaction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	CD14	_	PROPN	_	Number=Sing	_	_	_	_
14	distal	_	ADJ	_	Number=Sing	_	_	_	_
15	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
22	D3	_	PROPN	_	Number=Sing	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	partner	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
30	X	_	PROPN	_	_	_	_	_	_
31	receptor	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	VitD3	_	PROPN	_	Number=Sing	_	_	_	_
6	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	CD14	_	PROPN	_	Number=Sing	_	_	_	_
8	indirectly	_	ADV	_	_	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	some	_	DET	_	_	_	_	_	_
11	intermediary	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	critical	_	ADJ	_	Degree=Pos	_	_	_	_
18	role	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
23	process	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001847	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	U937	_	NUM	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	During	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	course	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	serious	_	ADJ	_	Degree=Pos	_	_	_	_
6	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
7	infections	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	LPS	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
18	receptors	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	generation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
26	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	paper	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	LPS	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	line	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	U937	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	followed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	rather	_	ADV	_	_	_	_	_	_
27	slow	_	ADJ	_	Degree=Pos	_	_	_	_
28	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	depending	_	VERB	_	VerbForm=Ger	_	_	_	_
31	on	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	rate	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
39	hydrolysis	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	degradation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p105	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	p100	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	under	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	conditions	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transduction	_	NOUN	_	Number=Sing	_	_	_	_
3	pathway	_	NOUN	_	Number=Sing	_	_	_	_
4	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	U937	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	involved	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
16	generation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
19	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
20	species	_	NOUN	_	Number=Plur	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	ROS	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	as	_	SCONJ	_	_	_	_	_	_
26	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
30	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
31	effects	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
34	on	_	ADP	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
38	activation	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	emission	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	fluorescent	_	ADJ	_	Degree=Pos	_	_	_	_
45	probe	_	NOUN	_	Number=Sing	_	_	_	_
46	reacting	_	VERB	_	VerbForm=Ger	_	_	_	_
47	intracellularly	_	ADV	_	_	_	_	_	_
48	with	_	ADP	_	_	_	_	_	_
49	hydrogen	_	NOUN	_	Number=Sing	_	_	_	_
50	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	ROS	_	NOUN	_	Number=Sing	_	_	_	_
3	pathway	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	use	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	other	_	ADJ	_	Degree=Pos	_	_	_	_
12	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	finding	_	NOUN	_	Number=Sing	_	_	_	_
3	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	phospholipase	_	NOUN	_	Number=Sing	_	_	_	_
6	A2	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	lipoxygenase	_	NOUN	_	Number=Sing	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	involved	_	ADJ	_	Degree=Pos	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	pathway	_	NOUN	_	Number=Sing	_	_	_	_
9	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	acidic	_	ADJ	_	Degree=Pos	_	_	_	_
12	sphingomyelinase	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	endolysosomial	_	ADJ	_	Degree=Pos	_	_	_	_
16	membrane	_	NOUN	_	Number=Sing	_	_	_	_
17	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	seem	_	VERB	_	VerbForm=Inf	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	LPS	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	NF	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	U937	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001849	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HSF2	_	NUM	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	inhibits	_	VERB	_	Number=Plur	_	_	_	_
7	hemin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	heat	_	NOUN	_	Number=Sing	_	_	_	_
11	shock	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	K562	_	NUM	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Acquisition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	heat	_	NOUN	_	Number=Sing	_	_	_	_
4	shock	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	DNA	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	heat	_	NOUN	_	Number=Sing	_	_	_	_
20	shock	_	NOUN	_	Number=Sing	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	hemin	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	K562	_	NUM	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	undergoing	_	VERB	_	VerbForm=Ger	_	_	_	_
29	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
30	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
6	consists	_	VERB	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	alternatively	_	ADV	_	_	_	_	_	_
10	spliced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
22	relative	_	ADJ	_	Degree=Pos	_	_	_	_
23	abundance	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	developmentally	_	ADV	_	_	_	_	_	_
26	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	varies	_	VERB	_	Number=Plur	_	_	_	_
29	between	_	ADP	_	_	_	_	_	_
30	different	_	ADJ	_	Degree=Pos	_	_	_	_
31	tissues	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	molar	_	ADJ	_	Degree=Pos	_	_	_	_
6	ratio	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	whether	_	SCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
27	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
28	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	functionally	_	ADV	_	_	_	_	_	_
30	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
31	roles	_	NOUN	_	Number=Plur	_	_	_	_
32	during	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	hemin	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
38	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
41	generated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	clones	_	NOUN	_	Number=Plur	_	_	_	_
44	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
45	different	_	ADJ	_	Degree=Pos	_	_	_	_
46	levels	_	NOUN	_	Number=Plur	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	alpha	_	NOUN	_	Number=Sing	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	beta	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	parental	_	ADJ	_	Degree=Pos	_	_	_	_
6	K562	_	NUM	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	isoform	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	predominantly	_	ADV	_	_	_	_	_	_
16	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	HSF2	_	PROPN	_	Number=Sing	_	_	_	_
19	can	_	AUX	_	VerbForm=Fin	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	upon	_	ADP	_	_	_	_	_	_
23	hemin	_	ADJ	_	Number=Sing	_	_	_	_
24	treatment	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	when	_	ADV	_	PronType=Int	_	_	_	_
5	HSF2	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	exceeding	_	VERB	_	VerbForm=Ger	_	_	_	_
13	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
16	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	hemin	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	DNA	_	PROPN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	heat	_	NOUN	_	Number=Sing	_	_	_	_
31	shock	_	NOUN	_	Number=Sing	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	repressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	whereas	_	SCONJ	_	_	_	_	_	_
37	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	alpha	_	NOUN	_	Number=Sing	_	_	_	_
42	results	_	NOUN	_	Number=Plur	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
45	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	hemin	_	NOUN	_	Number=Sing	_	_	_	_
47	response	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	hemin	_	ADJ	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	globin	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	marker	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	overexpressing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	beta	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	HSF2	_	NUM	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	negative	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulator	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	HSF2	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	during	_	ADP	_	_	_	_	_	_
16	hemin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
20	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	K562	_	NUM	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001850	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	function	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	putative	_	ADJ	_	Degree=Pos	_	_	_	_
6	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	type	_	NOUN	_	Number=Sing	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
18	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
20	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
5	antigen	_	NOUN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	sites	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	putative	_	ADJ	_	Degree=Pos	_	_	_	_
3	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	region	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
29	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
30	lines	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	nor	_	CCONJ	_	_	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	cis	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
39	negative	_	ADJ	_	Degree=Pos	_	_	_	_
40	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
41	element	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001852	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Involvement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
4	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	oxidant	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
8	subclone	_	ADJ	_	Number=Sing	_	_	_	_
9	Wurzburg	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
12	challenge	_	NOUN	_	Number=Sing	_	_	_	_
13	elevated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	[	_	PUNCT	_	_	_	_	_	_
15	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
16	+]	_	PUNCT	_	_	_	_	_	_
17	i	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	by	_	VERB	_	_	_	_	_	_
19	mobilizing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
21	+	_	SYM	_	_	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
24	stores	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	transient	_	ADJ	_	Degree=Pos	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	Wurzburg	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	response	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	slow	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	sustained	_	VERB	_	Degree=Pos	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	Wurzburg	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	influenced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	presence	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
19	EGTA	_	PROPN	_	Number=Sing	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	totally	_	ADV	_	_	_	_	_	_
23	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	loaded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	esterified	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
31	EGTA	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	NF	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	H2O2	_	PROPN	_	Number=Sing	_	_	_	_
18	potentiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	presence	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	sustained	_	VERB	_	VerbForm=Ger	_	_	_	_
28	high	_	ADJ	_	Degree=Pos	_	_	_	_
29	[	_	PUNCT	_	_	_	_	_	_
30	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
31	+]	_	SYM	_	_	_	_	_	_
32	i	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
33	following	_	VERB	_	VerbForm=Ger	_	_	_	_
34	thapsigargin	_	NOUN	_	Number=Sing	_	_	_	_
35	treatment	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	alpha	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	lipoate	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	N	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	acetylcysteine	_	NOUN	_	Number=Sing	_	_	_	_
14	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	at	_	ADV	_	_	_	_	_	_
19	least	_	ADV	_	Degree=Sup	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	part	_	ADJ	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	due	_	ADP	_	_	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	ability	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	stabilize	_	VERB	_	VerbForm=Inf	_	_	_	_
29	elevation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	[	_	PUNCT	_	_	_	_	_	_
32	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
33	+]	_	SYM	_	_	_	_	_	_
34	i	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
35	following	_	VERB	_	VerbForm=Ger	_	_	_	_
36	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
37	challenge	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Results	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	[	_	PUNCT	_	_	_	_	_	_
11	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
12	+	_	SYM	_	_	_	_	_	_
13	]	_	PUNCT	_	_	_	_	_	_
14	i	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	significant	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	oxidant	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001853	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Pancreatic	_	ADJ	_	Degree=Pos	_	_	_	_
2	islet	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	polymorphic	_	ADJ	_	Degree=Pos	_	_	_	_
7	DNA	_	PROPN	_	Number=Sing	_	_	_	_
8	markers	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
13	hepatocyte	_	ADJ	_	Number=Sing	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	3alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	beta	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	3gamma	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	4gamma	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	-	_	SYM	_	_	_	_	_	_
31	6	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	genes	_	NOUN	_	Number=Plur	_	_	_	_
3	encoding	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	functionally	_	ADV	_	_	_	_	_	_
6	related	_	ADJ	_	Degree=Pos	_	_	_	_
7	hepatocyte	_	ADJ	_	Number=Sing	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factors	_	NOUN	_	Number=Plur	_	_	_	_
10	HNF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	HNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	4alpha	_	PROPN	_	Number=Sing	_	_	_	_
17	play	_	VERB	_	VerbForm=Inf	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	critical	_	ADJ	_	Degree=Pos	_	_	_	_
20	role	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	normal	_	ADJ	_	Degree=Pos	_	_	_	_
23	pancreatic	_	ADJ	_	Number=Sing	_	_	_	_
24	beta-cell	_	NOUN	_	Number=Sing	_	_	_	_
25	function	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	liver	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	enriched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	result	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	two	_	NUM	_	NumType=Card	_	_	_	_
12	forms	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	early	_	ADJ	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	onset	_	NOUN	_	Degree=Pos	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	diabetes	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	maturity	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	onset	_	NOUN	_	Degree=Pos	_	_	_	_
24	diabetes	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	young	_	ADJ	_	Degree=Pos	_	_	_	_
28	[	_	PUNCT	_	_	_	_	_	_
29	MODY	_	NOUN	_	Number=Sing	_	_	_	_
30	]	_	PUNCT	_	_	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	MODY3	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	MODY1	_	NOUN	_	Number=Plur	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	which	_	PRON	_	PronType=Rel	_	_	_	_
38	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
42	glucose	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	insulin	_	NOUN	_	Degree=Pos	_	_	_	_
46	secretion	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	early	_	ADJ	_	Degree=Pos	_	_	_	_
49	disease	_	NOUN	_	Number=Sing	_	_	_	_
50	onset	_	NOUN	_	Number=Sing	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	autosomal	_	ADJ	_	Degree=Pos	_	_	_	_
54	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
55	inheritance	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
3	hierarchy	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	HNFs	_	NOUN	_	Number=Plur	_	_	_	_
6	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	other	_	ADJ	_	Degree=Pos	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	cascade	_	NOUN	_	Number=Sing	_	_	_	_
14	might	_	AUX	_	VerbForm=Fin	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	forms	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	MODY	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	late	_	ADJ	_	Degree=Pos	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	onset	_	NOUN	_	Number=Sing	_	_	_	_
28	type	_	NOUN	_	Number=Sing	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	diabetes	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	HNF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	3alpha	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	3	_	NUM	_	NumType=Card	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	3gamma	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	4gamma	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	6	_	NUM	_	NumType=Card	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	pancreatic	_	ADJ	_	Degree=Pos	_	_	_	_
29	beta-cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	identification	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	characterization	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	simple	_	ADJ	_	Degree=Pos	_	_	_	_
9	tandem	_	NOUN	_	Number=Sing	_	_	_	_
10	repeat	_	VERB	_	Degree=Pos	_	_	_	_
11	DNA	_	NOUN	_	Number=Sing	_	_	_	_
12	polymorphisms	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
17	HNF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	3alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	3	_	NUM	_	NumType=Card	_	_	_	_
23	beta	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	3gamma	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	-	_	SYM	_	_	_	_	_	_
29	4	_	NUM	_	NumType=Card	_	_	_	_
30	gamma	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	-	_	SYM	_	_	_	_	_	_
34	6	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	mapping	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	HNF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	6	_	NUM	_	NumType=Card	_	_	_	_
42	to	_	ADP	_	_	_	_	_	_
43	chromosome	_	VERB	_	Degree=Pos	_	_	_	_
44	bands	_	NOUN	_	Number=Plur	_	_	_	_
45	15q21.1	_	NUM	_	NumType=Card	_	_	_	_
46	-	_	SYM	_	_	_	_	_	_
47	21.2	_	NUM	_	NumType=Card	_	_	_	_
48	by	_	ADP	_	_	_	_	_	_
49	fluorescence	_	NOUN	_	Number=Sing	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	situ	_	NOUN	_	Number=Sing	_	_	_	_
52	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	markers	_	NOUN	_	Number=Plur	_	_	_	_
3	will	_	AUX	_	VerbForm=Fin	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	useful	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	study	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
12	variation	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	diabetes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001854	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Steel	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	SCL	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	during	_	ADP	_	_	_	_	_	_
7	normal	_	ADJ	_	Degree=Pos	_	_	_	_
8	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
9	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Steel	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	one	_	NUM	_	NumType=Card	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	growth	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	controls	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	SCL	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	also	_	ADV	_	_	_	_	_	_
22	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	Tcl	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	5	_	NUM	_	NumType=Card	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	Tal	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	involved	_	ADJ	_	Degree=Pos	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	erythropoiesis	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	SCL	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
17	blood	_	NOUN	_	Number=Sing	_	_	_	_
18	burst	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
21	unit	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	BFU	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	E	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	effects	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	Steel	_	NOUN	_	Number=Sing	_	_	_	_
34	factor	_	NOUN	_	Number=Sing	_	_	_	_
35	on	_	ADP	_	_	_	_	_	_
36	SCL	_	PROPN	_	Number=Sing	_	_	_	_
37	expression	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	SCONJ	_	_	_	_	_	_
39	proliferating	_	VERB	_	VerbForm=Ger	_	_	_	_
40	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	BFU	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	E-derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	colonies	_	NOUN	_	Number=Plur	_	_	_	_
5	increase	_	VERB	_	Number=Sing	_	_	_	_
6	progressively	_	ADV	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	size	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	as	_	SCONJ	_	_	_	_	_	_
11	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	number	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	day	_	NOUN	_	Number=Sing	_	_	_	_
18	7	_	NUM	_	NumType=Card	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	day	_	NOUN	_	Number=Sing	_	_	_	_
21	14	_	NUM	_	NumType=Card	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	culture	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	greatest	_	ADJ	_	Degree=Sup	_	_	_	_
28	increase	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	colony	_	NOUN	_	Number=Sing	_	_	_	_
31	size	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	10	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	fold	_	NOUN	_	Number=Sing	_	_	_	_
36	expansion	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
39	between	_	ADP	_	_	_	_	_	_
40	day	_	NOUN	_	Number=Sing	_	_	_	_
41	7	_	NUM	_	NumType=Card	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	day	_	NOUN	_	Number=Sing	_	_	_	_
44	10	_	NUM	_	NumType=Card	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	SCL	_	NOUN	_	Number=Sing	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	BFU	_	PROPN	_	Number=Sing	_	_	_	_
6	-E	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	highest	_	ADJ	_	Degree=Sup	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	day	_	NOUN	_	Number=Sing	_	_	_	_
14	7	_	NUM	_	NumType=Card	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	progressively	_	ADV	_	_	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	day	_	NOUN	_	Number=Sing	_	_	_	_
21	7	_	NUM	_	NumType=Card	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	day	_	NOUN	_	Number=Sing	_	_	_	_
24	14	_	NUM	_	NumType=Card	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	culture	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	association	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	SCL	_	NOUN	_	Number=Sing	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
35	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	SCL	_	NOUN	_	Number=Sing	_	_	_	_
5	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	decrease	_	VERB	_	VerbForm=Inf	_	_	_	_
10	significantly	_	ADV	_	_	_	_	_	_
11	between	_	ADP	_	_	_	_	_	_
12	day	_	NOUN	_	Number=Sing	_	_	_	_
13	7	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	day	_	NOUN	_	Number=Sing	_	_	_	_
16	14	_	NUM	_	NumType=Card	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	largely	_	ADV	_	_	_	_	_	_
25	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	decrease	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	SCL	_	PROPN	_	Number=Sing	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	SCL	_	PROPN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	Steel	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
11	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	then	_	ADV	_	PronType=Dem	_	_	_	_
14	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	BFU	_	PROPN	_	Number=Sing	_	_	_	_
3	-E	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	colonies	_	NOUN	_	Number=Plur	_	_	_	_
7	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	Steel	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	colony	_	NOUN	_	Number=Sing	_	_	_	_
13	size	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	significantly	_	ADV	_	_	_	_	_	_
16	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	control	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	day	_	NOUN	_	Number=Sing	_	_	_	_
3	7	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	day	_	NOUN	_	Number=Sing	_	_	_	_
6	10	_	NUM	_	NumType=Card	_	_	_	_
7	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
8	precursors	_	NOUN	_	Number=Plur	_	_	_	_
9	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	Steel	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	SCL	_	PROPN	_	Number=Sing	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	significantly	_	ADV	_	_	_	_	_	_
19	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	control	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	increase	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	SCL	_	PROPN	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	early	_	ADJ	_	Degree=Pos	_	_	_	_
9	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
10	precursors	_	NOUN	_	Number=Plur	_	_	_	_
11	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	Steel	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	one	_	NUM	_	NumType=Card	_	_	_	_
17	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	Steel	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	may	_	AUX	_	VerbForm=Fin	_	_	_	_
23	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
24	normal	_	ADJ	_	Degree=Pos	_	_	_	_
25	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
26	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	SCL	_	NOUN	_	Number=Sing	_	_	_	_
2	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	assessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
7	blot	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	day	_	NOUN	_	Number=Sing	_	_	_	_
10	7	_	NUM	_	NumType=Card	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
15	significantly	_	ADV	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	Steel	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
26	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
27	may	_	AUX	_	VerbForm=Fin	_	_	_	_
28	also	_	ADV	_	_	_	_	_	_
29	be	_	AUX	_	VerbForm=Inf	_	_	_	_
30	important	_	ADJ	_	Degree=Pos	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	increase	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	SCL	_	PROPN	_	Number=Sing	_	_	_	_
36	protein	_	NOUN	_	Number=Sing	_	_	_	_
37	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	response	_	NOUN	_	Number=Sing	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	Steel	_	PROPN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001873	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	AM580	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	stable	_	ADJ	_	Degree=Pos	_	_	_	_
5	benzoic	_	ADJ	_	Degree=Pos	_	_	_	_
6	derivative	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
9	acid	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	powerful	_	ADJ	_	Degree=Pos	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	selective	_	ADJ	_	Degree=Pos	_	_	_	_
15	cyto	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	effects	_	NOUN	_	Number=Plur	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	acute	_	ADJ	_	Degree=Pos	_	_	_	_
21	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	trans	_	NOUN	_	Number=Plur	_	_	_	_
4	retinoic	_	PROPN	_	Number=Sing	_	_	_	_
5	acid	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	successfully	_	ADV	_	_	_	_	_	_
11	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	cyto	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
17	treatment	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	acute	_	ADJ	_	Degree=Pos	_	_	_	_
20	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	APL	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Paradoxically	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	APL	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	express	_	VERB	_	Degree=Pos	_	_	_	_
6	PML	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	RAR	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	aberrant	_	ADJ	_	Degree=Pos	_	_	_	_
12	form	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
16	acid	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	RAR	_	PROPN	_	Number=Sing	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	specific	_	ADJ	_	Degree=Pos	_	_	_	_
30	t	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	15	_	NUM	_	NumType=Card	_	_	_	_
33	;	_	PUNCT	_	_	_	_	_	_
34	17	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
37	translocation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	AM580	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	stable	_	ADJ	_	Degree=Pos	_	_	_	_
9	retinobenzoic	_	ADJ	_	Number=Sing	_	_	_	_
10	derivative	_	NOUN	_	Number=Sing	_	_	_	_
11	originally	_	ADV	_	_	_	_	_	_
12	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	RAR	_	PROPN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	agonist	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	powerful	_	ADJ	_	Degree=Pos	_	_	_	_
22	inducer	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	maturation	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	NB4	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	APL	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	line	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	freshly	_	ADV	_	_	_	_	_	_
39	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	APL	_	NOUN	_	Number=Sing	_	_	_	_
41	blasts	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	APL	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	AM580	_	PROPN	_	Number=Sing	_	_	_	_
8	either	_	CCONJ	_	_	_	_	_	_
9	alone	_	ADV	_	_	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	combination	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
15	colony	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	G	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	CSF	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	compound	_	NOUN	_	Number=Sing	_	_	_	_
27	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
29	maturation	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	as	_	SCONJ	_	_	_	_	_	_
32	assessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	determination	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	levels	_	NOUN	_	Number=Plur	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
40	alkaline	_	NOUN	_	Number=Sing	_	_	_	_
41	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	CD11b	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	CD33	_	PROPN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	G	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	CSF	_	PROPN	_	Number=Sing	_	_	_	_
51	receptor	_	NOUN	_	Number=Sing	_	_	_	_
52	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	at	_	ADP	_	_	_	_	_	_
55	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
56	that	_	PRON	_	PronType=Rel	_	_	_	_
57	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
58	10	_	NUM	_	NumType=Card	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	to	_	ADP	_	_	_	_	_	_
61	100	_	NUM	_	NumType=Card	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
64	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
65	than	_	ADP	_	_	_	_	_	_
66	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
67	of	_	ADP	_	_	_	_	_	_
68	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
69	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
70	to	_	PART	_	_	_	_	_	_
71	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
72	similar	_	ADJ	_	Degree=Pos	_	_	_	_
73	effects	_	NOUN	_	Number=Plur	_	_	_	_
74	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	AM580	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	effective	_	ADJ	_	Degree=Pos	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
10	in	_	SCONJ	_	_	_	_	_	_
11	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	markers	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	HL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	60	_	NUM	_	NumType=Card	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	line	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	freshly	_	ADV	_	_	_	_	_	_
28	isolated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
29	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
34	blood	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	chronic	_	ADJ	_	Number=Sing	_	_	_	_
37	myelogenous	_	ADJ	_	Degree=Pos	_	_	_	_
38	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
39	patients	_	NOUN	_	Number=Plur	_	_	_	_
40	during	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	stable	_	ADJ	_	Degree=Pos	_	_	_	_
43	phase	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	disease	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	NB4	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
8	nonselective	_	ADJ	_	Degree=Pos	_	_	_	_
9	RAR	_	NOUN	_	Number=Sing	_	_	_	_
10	ligands	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	capable	_	ADJ	_	Degree=Pos	_	_	_	_
13	of	_	SCONJ	_	_	_	_	_	_
14	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	LAP	_	NOUN	_	Number=Sing	_	_	_	_
16	as	_	ADV	_	_	_	_	_	_
17	much	_	ADJ	_	Degree=Pos	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	AM580	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whereas	_	SCONJ	_	_	_	_	_	_
22	RAR	_	PROPN	_	Number=Sing	_	_	_	_
23	beta	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	RAR	_	PROPN	_	Number=Sing	_	_	_	_
27	gamma-specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	ligands	_	NOUN	_	Number=Plur	_	_	_	_
29	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	totally	_	ADV	_	_	_	_	_	_
31	ineffective	_	ADJ	_	Degree=Pos	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	AM580	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	more	_	ADV	_	_	_	_	_	_
8	powerful	_	ADJ	_	Degree=Pos	_	_	_	_
9	than	_	ADP	_	_	_	_	_	_
10	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
11	in	_	SCONJ	_	_	_	_	_	_
12	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	antigens	_	NOUN	_	Number=Plur	_	_	_	_
18	only	_	ADV	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	PML	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	RAR	_	NOUN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	present	_	ADJ	_	Degree=Pos	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	using	_	VERB	_	VerbForm=Ger	_	_	_	_
5	COS	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	7	_	NUM	_	NumType=Card	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	transiently	_	ADV	_	_	_	_	_	_
10	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	PML	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	RAR	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	normal	_	ADJ	_	Degree=Pos	_	_	_	_
18	RAR	_	NOUN	_	Number=Sing	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	show	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	AM580	_	PROPN	_	Number=Sing	_	_	_	_
24	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
27	affinity	_	NOUN	_	Number=Sing	_	_	_	_
28	than	_	ADP	_	_	_	_	_	_
29	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	both	_	DET	_	_	_	_	_	_
32	receptors	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	presence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	PML	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	RAR	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
13	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	much	_	ADV	_	_	_	_	_	_
17	better	_	ADJ	_	Degree=Cmp	_	_	_	_
18	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
21	acid	_	ADJ	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
24	element	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
27	promoters	_	NOUN	_	Number=Plur	_	_	_	_
28	than	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	natural	_	ADJ	_	Degree=Pos	_	_	_	_
31	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	whereas	_	ADV	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	presence	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	RAR	_	PROPN	_	Number=Sing	_	_	_	_
40	alpha	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	AM580	_	PROPN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
45	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
46	similar	_	ADJ	_	Degree=Pos	_	_	_	_
47	activity	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	strong	_	ADJ	_	Degree=Pos	_	_	_	_
6	cyto	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	potential	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	AM580	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	PML	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	RAR	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001882	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Suppression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	CD18	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
12	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	corneal	_	ADJ	_	Degree=Pos	_	_	_	_
16	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	PURPOSE	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	demonstrate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
5	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	cultured	_	VERB	_	Degree=Pos	_	_	_	_
8	corneal	_	ADJ	_	Degree=Pos	_	_	_	_
9	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	CD18	_	PROPN	_	Number=Sing	_	_	_	_
16	antigen	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
21	whether	_	SCONJ	_	_	_	_	_	_
22	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
23	directly	_	ADV	_	_	_	_	_	_
24	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
26	by	_	SCONJ	_	_	_	_	_	_
27	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Cultured	_	VERB	_	Degree=Pos	_	_	_	_
4	bovine	_	NOUN	_	Number=Sing	_	_	_	_
5	corneal	_	ADJ	_	Number=Sing	_	_	_	_
6	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	hours	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	40	_	NUM	_	NumType=Card	_	_	_	_
14	micron	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	ml	_	NOUN	_	Number=Sing	_	_	_	_
17	tumor	_	NOUN	_	Number=Sing	_	_	_	_
18	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	added	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	hour	_	NOUN	_	Number=Sing	_	_	_	_
6	before	_	ADP	_	_	_	_	_	_
7	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
8	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
12	group	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
5	separated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	volunteer	_	NOUN	_	Number=Sing	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	added	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	without	_	ADP	_	_	_	_	_	_
16	anti-CD18	_	ADJ	_	Degree=Pos	_	_	_	_
17	antibody	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	culture	_	NOUN	_	Number=Sing	_	_	_	_
3	plate	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	settled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	15	_	NUM	_	NumType=Card	_	_	_	_
8	minutes	_	NOUN	_	Number=Plur	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	37	_	NUM	_	NumType=Card	_	_	_	_
11	degrees	_	NOUN	_	Number=Plur	_	_	_	_
12	C	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	then	_	ADV	_	PronType=Dem	_	_	_	_
16	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	N	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	formyl	_	ADJ	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	methionyl	_	ADJ	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	leucyl	_	ADJ	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	phenylalanine	_	NOUN	_	Number=Sing	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	5	_	NUM	_	NumType=Card	_	_	_	_
31	minutes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Nonadherent	_	ADJ	_	Degree=Pos	_	_	_	_
2	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	removed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	SCONJ	_	_	_	_	_	_
6	sealing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	inverting	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	culture	_	NOUN	_	Number=Sing	_	_	_	_
11	well	_	ADV	_	Degree=Pos	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	localization	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
6	after	_	ADP	_	_	_	_	_	_
7	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
8	simulation	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	confocal	_	ADJ	_	Degree=Pos	_	_	_	_
13	immunocytochemistry	_	NOUN	_	Number=Sing	_	_	_	_
14	using	_	VERB	_	VerbForm=Ger	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	anti-p65	_	NOUN	_	NumType=Card	_	_	_	_
17	antibody	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
4	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	cultured	_	VERB	_	Degree=Pos	_	_	_	_
7	corneal	_	ADJ	_	Degree=Pos	_	_	_	_
8	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	significantly	_	ADV	_	_	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	exposure	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	451.4+/-45.4	_	NUM	_	NumType=Card	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	mm2	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	n	_	NOUN	_	Number=Sing	_	_	_	_
23	=	_	SYM	_	_	_	_	_	_
24	16	_	NUM	_	NumType=Card	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	control	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	156.7+/-27.3	_	NUM	_	NumType=Card	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	mm2	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	n	_	NOUN	_	Number=Sing	_	_	_	_
36	=	_	SYM	_	_	_	_	_	_
37	16	_	NUM	_	NumType=Card	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	P	_	NOUN	_	Number=Sing	_	_	_	_
40	<	_	PUNCT	_	_	_	_	_	_
41	0.01	_	NUM	_	NumType=Card	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	addition	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	anti-CD18	_	PROPN	_	NumType=Card	_	_	_	_
11	antibody	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	157.6+/-	_	NUM	_	NumType=Card	_	_	_	_
14	25.1	_	NUM	_	NumType=Card	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	mm2	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	n	_	NOUN	_	Number=Sing	_	_	_	_
20	=	_	SYM	_	_	_	_	_	_
21	8	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	P	_	NOUN	_	Number=Sing	_	_	_	_
24	<	_	PUNCT	_	_	_	_	_	_
25	0.01	_	NUM	_	NumType=Card	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	10	_	NUM	_	NumType=Card	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	-	_	SYM	_	_	_	_	_	_
34	7	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	M	_	NUM	_	NumType=Card	_	_	_	_
37	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	207.9+/-31.5	_	NUM	_	NumType=Card	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	/	_	PUNCT	_	_	_	_	_	_
42	mm2	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	n	_	NOUN	_	Number=Sing	_	_	_	_
45	=	_	SYM	_	_	_	_	_	_
46	10	_	NUM	_	NumType=Card	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	P	_	NOUN	_	Number=Sing	_	_	_	_
49	<	_	PUNCT	_	_	_	_	_	_
50	0.01	_	NUM	_	NumType=Card	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Immunocytochemistry	_	PROPN	_	Degree=Pos	_	_	_	_
2	60	_	NUM	_	NumType=Card	_	_	_	_
3	minutes	_	NOUN	_	Number=Plur	_	_	_	_
4	after	_	SCONJ	_	_	_	_	_	_
5	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	;	_	PUNCT	_	_	_	_	_	_
18	however	_	ADV	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	addition	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
24	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	translocate	_	VERB	_	VerbForm=Inf	_	_	_	_
28	into	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
4	tapered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
6	translocation	_	NOUN	_	Number=Sing	_	_	_	_
7	into	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Leukocyte	_	ADJ	_	Number=Sing	_	_	_	_
4	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	corneal	_	ADJ	_	Degree=Pos	_	_	_	_
8	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	CD18	_	PROPN	_	Number=Sing	_	_	_	_
16	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
9	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
10	;	_	PUNCT	_	_	_	_	_	_
11	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	due	_	ADP	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	part	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	suppression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
22	entry	_	NOUN	_	Number=Sing	_	_	_	_
23	into	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001885	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	B	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	OTF	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	positively	_	ADV	_	_	_	_	_	_
12	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	class	_	NOUN	_	Number=Sing	_	_	_	_
18	II	_	NUM	_	NumType=Card	_	_	_	_
19	transplantation	_	NOUN	_	Number=Sing	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	DRA	_	PROPN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	promoter	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	major	_	ADJ	_	Degree=Pos	_	_	_	_
6	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
7	class	_	NOUN	_	Number=Sing	_	_	_	_
8	II	_	PROPN	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	DRA	_	PROPN	_	Number=Sing	_	_	_	_
11	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	octamer	_	NOUN	_	Number=Sing	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	ATTTGCAT	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
23	DRA	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	B	_	ADJ	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	best	_	ADJ	_	Degree=Sup	_	_	_	_
3	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	OTF	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
16	OTF	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	report	_	NOUN	_	Number=Sing	_	_	_	_
3	directly	_	ADV	_	_	_	_	_	_
4	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	OTF	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	OTF	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	DRA	_	PROPN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	using	_	VERB	_	VerbForm=Ger	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	fractions	_	NOUN	_	Number=Plur	_	_	_	_
8	enriched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	octamer	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	OTF	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	positive	_	ADJ	_	Degree=Pos	_	_	_	_
21	functional	_	ADJ	_	Degree=Pos	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	OTF	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	DRA	_	PROPN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	OTF	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	enriched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	fractions	_	NOUN	_	Number=Plur	_	_	_	_
11	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
14	DRA	_	PROPN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	although	_	SCONJ	_	_	_	_	_	_
18	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
19	functionally	_	ADV	_	_	_	_	_	_
20	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	another	_	DET	_	_	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Recombinant	_	ADJ	_	Number=Sing	_	_	_	_
2	OTF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	vitro	_	NOUN	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	translation	_	NOUN	_	Number=Sing	_	_	_	_
13	could	_	AUX	_	VerbForm=Fin	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
16	DRA	_	PROPN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	vitro	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	ADJ	_	Number=Sing	_	_	_	_
3	transient	_	NOUN	_	Number=Sing	_	_	_	_
4	transfection	_	NOUN	_	Number=Sing	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	utilizing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	OTF	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	vector	_	NOUN	_	Number=Sing	_	_	_	_
13	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	similar	_	ADJ	_	Degree=Pos	_	_	_	_
16	findings	_	NOUN	_	Number=Plur	_	_	_	_
17	:	_	PUNCT	_	_	_	_	_	_
18	that	_	DET	_	_	_	_	_	_
19	OTF	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	DRA	_	PROPN	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	effect	_	NOUN	_	Number=Sing	_	_	_	_
32	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	intact	_	NOUN	_	Number=Sing	_	_	_	_
35	octamer	_	NOUN	_	Number=Sing	_	_	_	_
36	element	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	results	_	NOUN	_	Number=Plur	_	_	_	_
4	constitute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	direct	_	ADJ	_	Degree=Pos	_	_	_	_
8	evidence	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	positive	_	ADJ	_	Degree=Pos	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	octamer	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	DRA	_	PROPN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001888	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Modulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	gamma	_	NOUN	_	Number=Sing	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	beta-chain	_	NOUN	_	Number=Sing	_	_	_	_
12	controls	_	NOUN	_	Number=Plur	_	_	_	_
13	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	IFN	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	gamma	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
21	blood	_	NOUN	_	Number=Sing	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	IFN	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	potent	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	antiproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
9	effects	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	important	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	SCONJ	_	_	_	_	_	_
17	determining	_	VERB	_	VerbForm=Ger	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	development	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	polarized	_	VERB	_	Degree=Pos	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	any	_	DET	_	_	_	_	_	_
4	event	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	enables	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	become	_	VERB	_	VerbForm=Inf	_	_	_	_
11	less	_	ADV	_	Degree=Cmp	_	_	_	_
12	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	IFN	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	gamma	_	NOUN	_	Number=Sing	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	potentially	_	ADV	_	_	_	_	_	_
19	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
20	immune	_	ADJ	_	Degree=Pos	_	_	_	_
21	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	Ag	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	work	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
10	blood	_	NOUN	_	Number=Sing	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	TCR	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	expanded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	unresponsive	_	ADJ	_	Degree=Pos	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	IFN	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	gamma	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	as	_	SCONJ	_	_	_	_	_	_
33	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	lack	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	activation	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	jak	_	NOUN	_	Number=Sing	_	_	_	_
41	kinases	_	NOUN	_	Number=Plur	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	transcription	_	NOUN	_	Number=Sing	_	_	_	_
45	factor	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	alpha	_	NOUN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
53	signal	_	ADJ	_	Number=Sing	_	_	_	_
54	transducer	_	NOUN	_	Number=Sing	_	_	_	_
55	and	_	CCONJ	_	_	_	_	_	_
56	activator	_	NOUN	_	Number=Sing	_	_	_	_
57	of	_	ADP	_	_	_	_	_	_
58	transcription	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	nonresponsiveness	_	NOUN	_	Number=Sing	_	_	_	_
3	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	because	_	ADP	_	_	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	lack	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	beta	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	chain	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	accessory	_	ADJ	_	Degree=Pos	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IFN	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	gamma	_	NOUN	_	Number=Sing	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	while	_	SCONJ	_	_	_	_	_	_
27	at	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	same	_	ADJ	_	Degree=Pos	_	_	_	_
30	time	_	NOUN	_	Number=Sing	_	_	_	_
31	maintaining	_	VERB	_	VerbForm=Ger	_	_	_	_
32	IFN	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	gamma	_	NOUN	_	Number=Sing	_	_	_	_
35	receptor	_	NOUN	_	Number=Sing	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	chain	_	NOUN	_	Number=Sing	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	beta	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	chain	_	NOUN	_	Number=Sing	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	restored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	secondary	_	ADJ	_	Degree=Pos	_	_	_	_
12	TCR	_	NOUN	_	Number=Sing	_	_	_	_
13	ligation	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	PMA	_	NOUN	_	Number=Sing	_	_	_	_
16	treatment	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	T	_	DET	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	blasts	_	NOUN	_	Number=Plur	_	_	_	_
4	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	PMA	_	PROPN	_	Number=Sing	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	now	_	ADV	_	_	_	_	_	_
9	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	IFN	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	freshly	_	ADV	_	_	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	highly	_	ADV	_	_	_	_	_	_
6	enriched	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	>	_	PUNCT	_	_	_	_	_	_
9	98	_	NUM	_	NumType=Card	_	_	_	_
10	%	_	SYM	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	IFN	_	ADJ	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	gamma	_	NOUN	_	Number=Sing	_	_	_	_
20	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
21	;	_	PUNCT	_	_	_	_	_	_
22	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	can	_	AUX	_	VerbForm=Fin	_	_	_	_
25	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	IFN	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	gamma	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	express	_	ADJ	_	Number=Sing	_	_	_	_
32	beta-chain	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	as	_	ADP	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	progress	_	VERB	_	Number=Sing	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	primary	_	ADJ	_	Degree=Pos	_	_	_	_
9	TCR	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	secondary	_	ADJ	_	Degree=Pos	_	_	_	_
22	TCR	_	NOUN	_	Number=Sing	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	IFN	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	gamma	_	NOUN	_	Number=Sing	_	_	_	_
31	varies	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
35	may	_	AUX	_	VerbForm=Fin	_	_	_	_
36	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
37	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
38	ability	_	NOUN	_	Number=Sing	_	_	_	_
39	to	_	PART	_	_	_	_	_	_
40	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	ongoing	_	ADJ	_	Degree=Pos	_	_	_	_
44	immune	_	ADJ	_	Degree=Pos	_	_	_	_
45	response	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001890	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	double	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	stranded	_	VERB	_	Degree=Pos	_	_	_	_
9	phosphorothioate	_	ADJ	_	Degree=Pos	_	_	_	_
10	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Alteration	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	SCONJ	_	_	_	_	_	_
15	determining	_	VERB	_	VerbForm=Ger	_	_	_	_
16	how	_	ADV	_	PronType=Int	_	_	_	_
17	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	participate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	functions	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	antagonized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	several	_	ADJ	_	Degree=Pos	_	_	_	_
11	methods	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	each	_	DET	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	limitations	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	DNA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	achieved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	double	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	stranded	_	VERB	_	Degree=Pos	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	ds	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	phosphorothioate	_	ADJ	_	Degree=Pos	_	_	_	_
20	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	octamer	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	consensus	_	NOUN	_	Number=Sing	_	_	_	_
28	sequences	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	phosphorothioate	_	NOUN	_	Number=Sing	_	_	_	_
3	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
4	specifically	_	ADV	_	_	_	_	_	_
5	bound	_	ADJ	_	Degree=Pos	_	_	_	_
6	either	_	CCONJ	_	_	_	_	_	_
7	octamer	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
4	accumulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	more	_	ADV	_	_	_	_	_	_
8	effectively	_	ADV	_	_	_	_	_	_
9	than	_	ADP	_	_	_	_	_	_
10	standard	_	ADJ	_	Degree=Pos	_	_	_	_
11	ds	_	NOUN	_	Number=Sing	_	_	_	_
12	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	modulated	_	VERB	_	Degree=Pos	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	manner	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Octamer	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	reporter	_	NOUN	_	Number=Sing	_	_	_	_
8	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	PROPN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
21	virus	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	HIV	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	when	_	ADV	_	PronType=Int	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	appropriate	_	ADJ	_	Degree=Pos	_	_	_	_
31	phosphorothioate	_	NOUN	_	Number=Sing	_	_	_	_
32	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
33	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
34	added	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	transiently	_	ADV	_	_	_	_	_	_
38	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	B	_	NOUN	_	Number=Sing	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	line	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Addition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	phosphorothioate	_	ADJ	_	Number=Sing	_	_	_	_
4	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	octamer	_	NOUN	_	Number=Sing	_	_	_	_
9	consensus	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	secretion	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	degree	_	NOUN	_	Number=Sing	_	_	_	_
28	similar	_	ADJ	_	Degree=Pos	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
31	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	octamer	_	NOUN	_	Number=Sing	_	_	_	_
36	site	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ds	_	PROPN	_	Number=Sing	_	_	_	_
3	phosphorothioate	_	NOUN	_	Number=Sing	_	_	_	_
4	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
5	probably	_	ADV	_	_	_	_	_	_
6	compete	_	VERB	_	VerbForm=Inf	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
16	anti-viral	_	ADJ	_	Degree=Pos	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	other	_	ADJ	_	Degree=Pos	_	_	_	_
22	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
23	effects	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001892	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Signals	_	NOUN	_	Number=Plur	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	5	_	NUM	_	NumType=Card	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	helper	_	NOUN	_	Number=Sing	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Mouse	_	NOUN	_	Number=Sing	_	_	_	_
2	thymoma	_	NOUN	_	Number=Sing	_	_	_	_
3	line	_	NOUN	_	Number=Sing	_	_	_	_
4	EL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	produce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
10	such	_	ADJ	_	Degree=Pos	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	3	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	4	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	10	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
35	colony	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
38	factor	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	response	_	NOUN	_	Number=Sing	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
43	12	_	NUM	_	NumType=Card	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	myristate	_	NOUN	_	Number=Sing	_	_	_	_
46	13	_	NUM	_	NumType=Card	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	acetate	_	NOUN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	PMA	_	PROPN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	EL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
7	low	_	ADJ	_	Degree=Pos	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	5	_	NUM	_	NumType=Card	_	_	_	_
13	when	_	ADV	_	PronType=Int	_	_	_	_
14	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	PMA	_	PROPN	_	Number=Sing	_	_	_	_
17	alone	_	ADV	_	_	_	_	_	_
18	;	_	PUNCT	_	_	_	_	_	_
19	however	_	ADV	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
22	greatly	_	ADV	_	_	_	_	_	_
23	augments	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	PMA	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	5	_	NUM	_	NumType=Card	_	_	_	_
30	production	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	transient	_	ADJ	_	Degree=Pos	_	_	_	_
3	transfection	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	signals	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	PMA	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	5	_	NUM	_	NumType=Card	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
5	almost	_	ADV	_	_	_	_	_	_
6	completely	_	ADV	_	_	_	_	_	_
7	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	PMA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	as	_	ADV	_	_	_	_	_	_
22	well	_	ADV	_	Degree=Pos	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	positively	_	ADV	_	_	_	_	_	_
12	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	manner	_	NOUN	_	Number=Sing	_	_	_	_
18	opposite	_	ADJ	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	NFs	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	5	_	NUM	_	NumType=Card	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	cAMP	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	PMA	_	PROPN	_	Number=Sing	_	_	_	_
23	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	properties	_	NOUN	_	Number=Plur	_	_	_	_
25	similar	_	ADJ	_	Degree=Pos	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	t	_	NOUN	_	Number=Sing	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	P	_	NOUN	_	Number=Sing	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	defined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
15	element	_	NOUN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	PMA	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	calcium	_	NOUN	_	Number=Sing	_	_	_	_
20	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	A23187	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	shares	_	NOUN	_	Number=Plur	_	_	_	_
26	sequence	_	NOUN	_	Number=Sing	_	_	_	_
27	similarity	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	T	_	NOUN	_	Number=Sing	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	binding	_	NOUN	_	Number=Sing	_	_	_	_
41	sites	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	attempted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
5	whether	_	SCONJ	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	P	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	P	_	NOUN	_	Number=Sing	_	_	_	_
18	sequence	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	related	_	ADJ	_	Degree=Pos	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	AT	_	NOUN	_	_	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	electromobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	both	_	CCONJ	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	P65	_	NUM	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	P65	_	NUM	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	P50	_	NUM	_	NumType=Card	_	_	_	_
16	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	AT	_	ADP	_	_	_	_	_	_
22	bound	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	P	_	NOUN	_	Number=Sing	_	_	_	_
26	sequence	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	specificity	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	AT	_	PROPN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	more	_	ADV	_	_	_	_	_	_
11	similar	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	P	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	only	_	ADV	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	small	_	ADJ	_	Degree=Pos	_	_	_	_
24	amount	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	P65	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	P	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	component	_	NOUN	_	Number=Sing	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	components	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	AT	_	PROPN	_	_	_	_	_	_
13	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	potential	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	reconstitute	_	VERB	_	VerbForm=Inf	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	P	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	whereas	_	SCONJ	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	PROPN	_	Number=Sing	_	_	_	_
27	B	_	PROPN	_	Number=Sing	_	_	_	_
28	alone	_	ADV	_	_	_	_	_	_
29	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	not	_	PART	_	_	_	_	_	_
31	account	_	VERB	_	VerbForm=Inf	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	P	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
39	crude	_	NOUN	_	Number=Sing	_	_	_	_
40	extract	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	AT	_	ADP	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	like	_	ADJ	_	Degree=Pos	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	involved	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	regulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	4	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	5	_	NUM	_	NumType=Card	_	_	_	_
27	genes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001910	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Octamer	_	NOUN	_	Number=Sing	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specificity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Antibodies	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	exclusively	_	ADV	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	B	_	ADJ	_	Number=Sing	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	antibody	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	encoding	_	VERB	_	Degree=Pos	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	immunoglobulin	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	Ig	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	also	_	ADV	_	_	_	_	_	_
19	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	B	_	ADJ	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	octamer	_	NOUN	_	Number=Sing	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	ATGCAAAT	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	present	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	Ig	_	ADJ	_	Degree=Pos	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	important	_	ADJ	_	Degree=Pos	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	tissue	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	motif	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	so	_	ADV	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	octamer	_	NOUN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	Oct	_	X	_	Number=Sing	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	OTF	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Oct	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	present	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	all	_	DET	_	_	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	types	_	NOUN	_	Number=Plur	_	_	_	_
12	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	so	_	ADV	_	_	_	_	_	_
14	far	_	ADV	_	Degree=Pos	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	whereas	_	SCONJ	_	_	_	_	_	_
17	Oct	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2A	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	Oct	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2B	_	NOUN	_	Number=Sing	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	mainly	_	ADV	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	three	_	NUM	_	NumType=Card	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	same	_	ADJ	_	Degree=Pos	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	specificity	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
11	affinity	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Ig	_	NOUN	_	Degree=Pos	_	_	_	_
12	genes	_	NOUN	_	Number=Plur	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	at	_	ADV	_	_	_	_	_	_
16	least	_	ADV	_	Degree=Sup	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	part	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	type	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	Oct	_	NOUN	_	Number=Sing	_	_	_	_
25	factors	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	there	_	PRON	_	_	_	_	_	_
30	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	both	_	CCONJ	_	_	_	_	_	_
32	quantitative	_	ADJ	_	Degree=Pos	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	qualitative	_	ADJ	_	Degree=Pos	_	_	_	_
35	differences	_	NOUN	_	Number=Plur	_	_	_	_
36	between	_	ADP	_	_	_	_	_	_
37	Oct	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	Oct	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	2	_	NUM	_	NumType=Card	_	_	_	_
44	factors	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	number	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	octamer	_	ADJ	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	variants	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Many	_	ADJ	_	Degree=Pos	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
4	may	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	created	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
9	splicing	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	primary	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcript	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	one	_	NUM	_	NumType=Card	_	_	_	_
16	Oct	_	PROPN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	function	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	fine	_	ADJ	_	Degree=Pos	_	_	_	_
28	tuning	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001916	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Retinoblastoma	_	PROPN	_	Number=Sing	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	Oct	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	DNA	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	enhances	_	NOUN	_	Number=Plur	_	_	_	_
15	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	8	_	NUM	_	NumType=Card	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	defective	_	ADJ	_	Degree=Pos	_	_	_	_
7	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	unable	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	transcribe	_	VERB	_	VerbForm=Inf	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	HLA	_	PROPN	_	Number=Sing	_	_	_	_
15	class	_	NOUN	_	Number=Sing	_	_	_	_
16	II	_	PROPN	_	Number=Sing	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	IFN	_	ADJ	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	gamma	_	NOUN	_	Number=Sing	_	_	_	_
24	treatment	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	reconstitution	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	functional	_	ADJ	_	Degree=Pos	_	_	_	_
30	Rb	_	NOUN	_	Number=Sing	_	_	_	_
31	rescues	_	VERB	_	Number=Plur	_	_	_	_
32	IFN	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	gamma	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	class	_	NOUN	_	Number=Sing	_	_	_	_
38	II	_	NUM	_	NumType=Card	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	expression	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Rb	_	PROPN	_	Number=Sing	_	_	_	_
8	rescue	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	class	_	NOUN	_	Number=Sing	_	_	_	_
12	II	_	NUM	_	Number=Sing	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Rb	_	PROPN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	HLA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	DRA	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	prototype	_	NOUN	_	Number=Sing	_	_	_	_
22	class	_	NOUN	_	Number=Sing	_	_	_	_
23	II	_	NUM	_	NumType=Card	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Oct	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	POU	_	NOUN	_	Number=Sing	_	_	_	_
7	domain	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	repressor	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	HLA	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	DRA	_	PROPN	_	Number=Sing	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	Rb	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	defective	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Rb	_	NOUN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Oct	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	thus	_	ADV	_	_	_	_	_	_
12	relieving	_	VERB	_	VerbForm=Ger	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	repressive	_	ADJ	_	Degree=Pos	_	_	_	_
15	effect	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Oct	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	repress	_	VERB	_	VerbForm=Inf	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	8	_	NUM	_	NumType=Card	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Oct	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	DNA	_	NOUN	_	Number=Sing	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	Rb	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lines	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
21	8	_	NUM	_	NumType=Card	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	lines	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001917	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IK	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	HLA	_	PROPN	_	Number=Sing	_	_	_	_
11	class	_	NOUN	_	Number=Sing	_	_	_	_
12	II	_	NUM	_	NumType=Card	_	_	_	_
13	antigens	_	NOUN	_	Number=Plur	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	HLA	_	PROPN	_	Number=Sing	_	_	_	_
18	class	_	NOUN	_	Number=Sing	_	_	_	_
19	II	_	NUM	_	NumType=Card	_	_	_	_
20	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	Raji	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	line	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	major	_	ADJ	_	Degree=Pos	_	_	_	_
5	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
6	complex	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	MHC	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	class	_	NOUN	_	Number=Sing	_	_	_	_
11	II	_	NUM	_	NumType=Card	_	_	_	_
12	antigens	_	NOUN	_	Number=Plur	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	professional	_	ADJ	_	Degree=Pos	_	_	_	_
17	antigen	_	NOUN	_	Number=Sing	_	_	_	_
18	presenting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	APCs	_	NOUN	_	Number=Plur	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	can	_	AUX	_	VerbForm=Fin	_	_	_	_
25	also	_	ADV	_	_	_	_	_	_
26	be	_	AUX	_	VerbForm=Inf	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	interferon	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	gamma	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	IFN	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	gamma	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	on	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	majority	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	non	_	X	_	_	_	_	_	_
43	professional	_	ADJ	_	Degree=Pos	_	_	_	_
44	APCs	_	NOUN	_	Number=Plur	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	e.g.	_	X	_	_	_	_	_	_
47	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	recently	_	ADV	_	_	_	_	_	_
4	characterised	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	new	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	IK	_	PROPN	_	Number=Sing	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
14	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IFN	_	ADJ	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	gamma	_	NOUN	_	Number=Sing	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	MHC	_	PROPN	_	Number=Sing	_	_	_	_
22	class	_	NOUN	_	Number=Sing	_	_	_	_
23	II	_	NUM	_	NumType=Card	_	_	_	_
24	antigens	_	NOUN	_	Number=Plur	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	novel	_	NOUN	_	Number=Sing	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	IK	_	PROPN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	MHC	_	PROPN	_	Number=Sing	_	_	_	_
12	class	_	NOUN	_	Number=Sing	_	_	_	_
13	II	_	NUM	_	NumType=Card	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	since	_	ADP	_	_	_	_	_	_
16	over	_	ADP	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	stable	_	ADJ	_	Degree=Pos	_	_	_	_
24	transfection	_	NOUN	_	Number=Sing	_	_	_	_
25	into	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	total	_	ADJ	_	Degree=Pos	_	_	_	_
33	disappearance	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
36	MHC	_	PROPN	_	Number=Sing	_	_	_	_
37	class	_	NOUN	_	Number=Sing	_	_	_	_
38	II	_	NUM	_	NumType=Card	_	_	_	_
39	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
40	expression	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	class	_	NOUN	_	Number=Sing	_	_	_	_
3	II	_	NUM	_	NumType=Card	_	_	_	_
4	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	IFN	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	gamma	_	NOUN	_	Number=Sing	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	MHC	_	PROPN	_	Number=Sing	_	_	_	_
19	class	_	NOUN	_	Number=Sing	_	_	_	_
20	II	_	NUM	_	NumType=Card	_	_	_	_
21	expressions	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Examination	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
4	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	IK	_	PROPN	_	Number=Sing	_	_	_	_
7	stably	_	ADV	_	_	_	_	_	_
8	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	clones	_	NOUN	_	Number=Plur	_	_	_	_
10	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	reduction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
16	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IK	_	PROPN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	key	_	ADJ	_	Degree=Pos	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	MHC	_	PROPN	_	Number=Sing	_	_	_	_
20	class	_	NOUN	_	Number=Sing	_	_	_	_
21	II	_	NUM	_	NumType=Card	_	_	_	_
22	antigens	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	that	_	DET	_	_	_	_	_	_
25	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	IK	_	PROPN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	upstream	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
35	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
36	pathway	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001925	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Barr	_	PROPN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	VERB	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	CD21	_	PROPN	_	Number=Sing	_	_	_	_
8	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	initial	_	ADJ	_	Degree=Pos	_	_	_	_
11	viral	_	ADJ	_	Degree=Pos	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	via	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Barr	_	PROPN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EBV	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	oncogenic	_	ADJ	_	Degree=Pos	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	infects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	via	_	ADP	_	_	_	_	_	_
23	CD21	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	CR2	_	NOUN	_	Number=Sing	_	_	_	_
27	complement	_	NOUN	_	Number=Sing	_	_	_	_
28	receptor	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	enable	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	EBV	_	PROPN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	infect	_	VERB	_	VerbForm=Inf	_	_	_	_
10	nonactivated	_	ADJ	_	Degree=Pos	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	noncycling	_	VERB	_	Degree=Pos	_	_	_	_
13	B	_	ADJ	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
16	compelling	_	ADJ	_	Degree=Pos	_	_	_	_
17	evidence	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	sequence	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	events	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	EBV	_	PROPN	_	Number=Sing	_	_	_	_
26	binding	_	VERB	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	CD21	_	PROPN	_	Number=Sing	_	_	_	_
29	on	_	SCONJ	_	_	_	_	_	_
30	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	human	_	ADJ	_	Degree=Pos	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	rapidly	_	ADV	_	_	_	_	_	_
36	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
41	transcription	_	NOUN	_	Number=Sing	_	_	_	_
42	factor	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	which	_	PRON	_	PronType=Rel	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	turn	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
53	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
54	activation	_	NOUN	_	Number=Sing	_	_	_	_
55	of	_	ADP	_	_	_	_	_	_
56	Wp	_	NOUN	_	Number=Sing	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
59	initial	_	ADJ	_	Degree=Pos	_	_	_	_
60	viral	_	ADJ	_	Degree=Pos	_	_	_	_
61	latent	_	ADJ	_	Degree=Pos	_	_	_	_
62	gene	_	NOUN	_	Number=Sing	_	_	_	_
63	promoter	_	NOUN	_	Number=Sing	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	EBV	_	PROPN	_	Number=Sing	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
7	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	SCONJ	_	_	_	_	_	_
10	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	B	_	NOUN	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	triggers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
21	signaling	_	NOUN	_	Number=Sing	_	_	_	_
22	pathway	_	NOUN	_	Number=Sing	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	infection	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001926	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	PPARgamma	_	PROPN	_	Number=Sing	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	adipocyte	_	ADJ	_	Number=Sing	_	_	_	_
9	fatty	_	NOUN	_	Number=Sing	_	_	_	_
10	acid	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	peroxisome	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	proliferator	_	NOUN	_	Number=Sing	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	PPARgamma	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	member	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	ligand	_	NOUN	_	Number=Sing	_	_	_	_
21	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	key	_	ADJ	_	Degree=Pos	_	_	_	_
28	role	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	anti-diabetic	_	ADJ	_	Degree=Pos	_	_	_	_
32	actions	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	thiazolidinediones	_	NOUN	_	Number=Plur	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	TZDs	_	NOUN	_	Number=Plur	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	PPARgamma	_	PROPN	_	Number=Sing	_	_	_	_
2	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	many	_	ADJ	_	Degree=Pos	_	_	_	_
7	genes	_	NOUN	_	Number=Plur	_	_	_	_
8	involved	_	VERB	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	lipid	_	ADJ	_	Degree=Pos	_	_	_	_
11	anabolism	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	including	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	adipocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	fatty	_	NOUN	_	Number=Sing	_	_	_	_
17	acid	_	NOUN	_	Number=Sing	_	_	_	_
18	binding	_	VERB	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	aP2	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	key	_	ADJ	_	Degree=Pos	_	_	_	_
28	regulator	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	adipocyte	_	NOUN	_	Degree=Pos	_	_	_	_
31	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	PPARgamma	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	up	_	ADV	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	activated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	PPARgamma	_	NOUN	_	Number=Sing	_	_	_	_
4	may	_	AUX	_	VerbForm=Fin	_	_	_	_
5	play	_	VERB	_	VerbForm=Inf	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	foam	_	VERB	_	VerbForm=Inf	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	atherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
23	lesions	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	natural	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
8	PPARgamma	_	PROPN	_	Number=Sing	_	_	_	_
9	agonists	_	NOUN	_	Number=Plur	_	_	_	_
10	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	time	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	dose	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	increases	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	aP2	_	NOUN	_	Number=Sing	_	_	_	_
20	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	primary	_	ADJ	_	Degree=Pos	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	line	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	THP	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	PPARgamma	_	PROPN	_	Number=Sing	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	play	_	VERB	_	VerbForm=Inf	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	function	_	NOUN	_	Number=Sing	_	_	_	_
16	analogous	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	well	_	ADV	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	adipocytes	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001927	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	blocking	_	NOUN	_	Number=Sing	_	_	_	_
5	element	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	delta	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	segments	_	NOUN	_	Number=Plur	_	_	_	_
12	within	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	delta	_	PROPN	_	Number=Sing	_	_	_	_
21	locus	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	TCR	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	delta	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	segments	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	organized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	within	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	single	_	ADJ	_	Degree=Pos	_	_	_	_
17	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
18	locus	_	NOUN	_	Number=Sing	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	differentially	_	ADV	_	_	_	_	_	_
22	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	during	_	ADP	_	_	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	development	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	blocking	_	NOUN	_	Number=Sing	_	_	_	_
5	element	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	BEAD	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	blocking	_	NOUN	_	Number=Sing	_	_	_	_
13	element	_	NOUN	_	Number=Sing	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	delta	_	NOUN	_	Number=Sing	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	2.0	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kb	_	NOUN	_	Number=Sing	_	_	_	_
26	region	_	NOUN	_	Number=Sing	_	_	_	_
27	3	_	NUM	_	NumType=Card	_	_	_	_
28	'	_	PUNCT	_	_	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	TCR	_	NOUN	_	Number=Sing	_	_	_	_
31	delta	_	NOUN	_	Number=Sing	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	segments	_	NOUN	_	Number=Plur	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	5	_	NUM	_	NumType=Card	_	_	_	_
36	'	_	NOUN	_	Number=Plur	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	TCR	_	NOUN	_	Number=Sing	_	_	_	_
39	alpha	_	NOUN	_	Number=Sing	_	_	_	_
40	joining	_	VERB	_	VerbForm=Ger	_	_	_	_
41	gene	_	NOUN	_	Number=Sing	_	_	_	_
42	segments	_	NOUN	_	Number=Plur	_	_	_	_
43	within	_	ADP	_	_	_	_	_	_
44	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
45	locus	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	BEAD	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	ability	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	TCR	_	PROPN	_	Number=Sing	_	_	_	_
10	delta	_	NOUN	_	Number=Sing	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	Edelta	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	when	_	ADV	_	PronType=Int	_	_	_	_
20	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	between	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	two	_	NUM	_	NumType=Card	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	chromatin	_	ADJ	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	integrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	construct	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	BEAD	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	functions	_	NOUN	_	Number=Plur	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	boundary	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	separates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	TCR	_	NOUN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	delta	_	PROPN	_	Number=Sing	_	_	_	_
18	locus	_	NOUN	_	Number=Sing	_	_	_	_
19	into	_	ADP	_	_	_	_	_	_
20	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
21	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	domains	_	NOUN	_	Number=Plur	_	_	_	_
23	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	Edelta	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	TCR	_	NOUN	_	Number=Sing	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	that	_	SCONJ	_	_	_	_	_	_
34	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
35	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	Edelta	_	PROPN	_	Number=Sing	_	_	_	_
37	from	_	SCONJ	_	_	_	_	_	_
38	opening	_	VERB	_	VerbForm=Ger	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	TCR	_	NOUN	_	Number=Sing	_	_	_	_
44	alpha	_	NOUN	_	Number=Sing	_	_	_	_
45	joining	_	VERB	_	VerbForm=Ger	_	_	_	_
46	gene	_	NOUN	_	Number=Sing	_	_	_	_
47	segments	_	NOUN	_	Number=Plur	_	_	_	_
48	for	_	ADP	_	_	_	_	_	_
49	VDJ	_	PROPN	_	Number=Sing	_	_	_	_
50	recombination	_	NOUN	_	Number=Sing	_	_	_	_
51	at	_	ADP	_	_	_	_	_	_
52	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
53	early	_	ADJ	_	Degree=Pos	_	_	_	_
54	stage	_	NOUN	_	Number=Sing	_	_	_	_
55	of	_	ADP	_	_	_	_	_	_
56	T	_	NOUN	_	Number=Sing	_	_	_	_
57	cell	_	NOUN	_	Number=Sing	_	_	_	_
58	development	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001947	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	CD45RO	_	NOUN	_	Number=Sing	_	_	_	_
8	+	_	SYM	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	CD45RA	_	NOUN	_	Number=Sing	_	_	_	_
11	+	_	SYM	_	_	_	_	_	_

1	T	_	NUM	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	subsets	_	NOUN	_	Number=Plur	_	_	_	_
4	during	_	ADP	_	_	_	_	_	_
5	aging	_	NOUN	_	Number=Sing	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	increase	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	ratio	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	memory	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	naive	_	ADJ	_	Degree=Pos	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	postulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	underlie	_	VERB	_	VerbForm=Inf	_	_	_	_
17	immune	_	ADJ	_	Degree=Pos	_	_	_	_
18	hyporesponsiveness	_	NOUN	_	Number=Sing	_	_	_	_
19	accompanying	_	VERB	_	VerbForm=Ger	_	_	_	_
20	aging	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	analyses	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	memory	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	CD45RO	_	NOUN	_	Number=Sing	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	naive	_	ADJ	_	Degree=Pos	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	CD45RA	_	NOUN	_	Number=Sing	_	_	_	_
25	+	_	SYM	_	_	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_

1	T	_	NUM	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	subsets	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	young	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
8	donors	_	NOUN	_	Number=Plur	_	_	_	_
9	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	regardless	_	ADV	_	_	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	donor	_	NOUN	_	Number=Sing	_	_	_	_
16	age	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	memory	_	NOUN	_	Number=Sing	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	significantly	_	ADV	_	_	_	_	_	_
24	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	TNF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	mediated	_	VERB	_	Degree=Pos	_	_	_	_
34	induction	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	PROPN	_	Number=Sing	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	localization	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	both	_	DET	_	_	_	_	_	_
14	memory	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	naive	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	subsets	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	irrespective	_	ADJ	_	_	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	age	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	donor	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	levels	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
34	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	significantly	_	ADV	_	_	_	_	_	_
36	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	both	_	DET	_	_	_	_	_	_
39	subsets	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	T	_	PROPN	_	Number=Sing	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	from	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	when	_	ADV	_	PronType=Int	_	_	_	_
49	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	young	_	ADJ	_	Degree=Pos	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Examination	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	mediated	_	VERB	_	Degree=Pos	_	_	_	_
13	degradation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	both	_	DET	_	_	_	_	_	_
19	memory	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	naive	_	ADJ	_	Degree=Pos	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	elderly	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	severely	_	ADV	_	_	_	_	_	_
29	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	thus	_	ADV	_	_	_	_	_	_
32	contributing	_	VERB	_	VerbForm=Ger	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	lowered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	induction	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	age	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	related	_	ADJ	_	Degree=Pos	_	_	_	_
8	decrease	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	NFkappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	decrease	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	anti-CD3	_	ADJ	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	both	_	DET	_	_	_	_	_	_
31	memory	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	naive	_	ADJ	_	Degree=Pos	_	_	_	_
34	T	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	subsets	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	age	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	related	_	ADJ	_	Degree=Pos	_	_	_	_
12	hyporesponsiveness	_	NOUN	_	Number=Sing	_	_	_	_
13	can	_	AUX	_	VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	attributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	skewing	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	population	_	NOUN	_	Number=Sing	_	_	_	_
25	towards	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	memory	_	NOUN	_	Number=Sing	_	_	_	_
28	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	elderly	_	NOUN	_	Degree=Pos	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001949	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Patterns	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Pan	_	PROPN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Pan	_	PROPN	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	endocrine	_	NOUN	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	complex	_	ADJ	_	Degree=Pos	_	_	_	_
17	formation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Pan	_	PROPN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	at	_	ADV	_	_	_	_	_	_
6	least	_	ADV	_	Degree=Sup	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	Pan	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	Pan	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	E47	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	E12	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	respectively	_	ADV	_	_	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
34	RNA	_	PROPN	_	Number=Sing	_	_	_	_
35	splicing	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	analyses	_	NOUN	_	Number=Plur	_	_	_	_
4	performed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	rat	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	mouse	_	NOUN	_	Number=Sing	_	_	_	_
9	tissues	_	NOUN	_	Number=Plur	_	_	_	_
10	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	ubiquitously	_	ADV	_	_	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	Pan	_	NOUN	_	Number=Sing	_	_	_	_
15	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	abundance	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	distribution	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	form	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	Pan	_	NOUN	_	Number=Sing	_	_	_	_
27	proteins	_	NOUN	_	Number=Plur	_	_	_	_
28	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	not	_	PART	_	_	_	_	_	_
30	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
31	clearly	_	ADV	_	_	_	_	_	_
32	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	representing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	endocrine	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	fibroblast	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
12	lineages	_	NOUN	_	Number=Plur	_	_	_	_
13	using	_	VERB	_	VerbForm=Ger	_	_	_	_
14	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
15	antisera	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	detect	_	VERB	_	VerbForm=Inf	_	_	_	_
18	E2A	_	PROPN	_	Number=Sing	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	significant	_	ADJ	_	Degree=Pos	_	_	_	_
24	E2A	_	PROPN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	developed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
6	antibody	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	Yae	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	Pan	_	PROPN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	E2A	_	PROPN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	Yae	_	PROPN	_	Number=Sing	_	_	_	_
24	antibody	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	variety	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	endocrine	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	nonendocrine	_	NOUN	_	Degree=Pos	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	lineages	_	NOUN	_	Number=Plur	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	differences	_	NOUN	_	Number=Plur	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	Pan	_	PROPN	_	Number=Sing	_	_	_	_
39	/	_	PUNCT	_	_	_	_	_	_
40	E2A	_	PROPN	_	Number=Sing	_	_	_	_
41	protein	_	NOUN	_	Number=Sing	_	_	_	_
42	expression	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	subcellular	_	ADJ	_	Degree=Pos	_	_	_	_
45	localization	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	heteromeric	_	ADJ	_	Degree=Pos	_	_	_	_
49	complex	_	ADJ	_	Number=Sing	_	_	_	_
50	formation	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	previous	_	ADJ	_	Degree=Pos	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	using	_	VERB	_	VerbForm=Ger	_	_	_	_
8	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
9	antiseras	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	detect	_	VERB	_	VerbForm=Inf	_	_	_	_
12	Pan	_	PROPN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	E2A	_	PROPN	_	Number=Sing	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
18	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
20	levels	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	Pan	_	PROPN	_	Number=Sing	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	GH	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	PRL	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	insulin	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	producing	_	VERB	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	T-lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	IEF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	pancreatic	_	ADJ	_	Degree=Pos	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	complex	_	NOUN	_	Number=Sing	_	_	_	_
14	believed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	insulin	_	ADJ	_	Degree=Pos	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	consist	_	VERB	_	VerbForm=Inf	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	at	_	ADV	_	_	_	_	_	_
26	least	_	ADV	_	Degree=Sup	_	_	_	_
27	two	_	NUM	_	NumType=Card	_	_	_	_
28	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
29	species	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	one	_	NUM	_	NumType=Card	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	which	_	PRON	_	PronType=Int	_	_	_	_
34	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	not	_	PART	_	_	_	_	_	_
36	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
37	Pan	_	NOUN	_	Number=Sing	_	_	_	_
38	molecules	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	postulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
8	endocrine	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	pancreatic	_	ADJ	_	Degree=Pos	_	_	_	_
12	endocrine	_	NOUN	_	Number=Sing	_	_	_	_
13	beta-cells	_	NOUN	_	Number=Plur	_	_	_	_
14	share	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	identical	_	ADJ	_	Degree=Pos	_	_	_	_
16	Pan	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	E2A	_	PROPN	_	Number=Sing	_	_	_	_
19	complexes	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	native	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	Western	_	ADJ	_	Degree=Pos	_	_	_	_
24	analyses	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	pituitary	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	endocrine	_	NOUN	_	Degree=Pos	_	_	_	_
29	beta-cells	_	NOUN	_	Number=Plur	_	_	_	_
30	detect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	Pan	_	NOUN	_	Number=Sing	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	type	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	specific	_	ADJ	_	Degree=Pos	_	_	_	_
39	complexes	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001953	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Coupling	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	signal	_	ADJ	_	Degree=Pos	_	_	_	_
5	response	_	NOUN	_	Number=Sing	_	_	_	_
6	domain	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	kappa	_	VERB	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
14	pathways	_	NOUN	_	Number=Plur	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	eukaryotic	_	ADJ	_	Degree=Pos	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	PROPN	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	central	_	ADJ	_	Degree=Pos	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
20	virus	_	NOUN	_	Number=Sing	_	_	_	_
21	type	_	NOUN	_	Number=Sing	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	many	_	ADJ	_	Degree=Pos	_	_	_	_
26	aspects	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
30	program	_	NOUN	_	Number=Sing	_	_	_	_
31	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
32	normal	_	ADJ	_	Degree=Pos	_	_	_	_
33	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	growth	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	tightly	_	ADV	_	_	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
15	compartment	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
19	subunit	_	NOUN	_	Number=Sing	_	_	_	_
20	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	kappa	_	VERB	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	alpha	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
3	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	rapidly	_	ADV	_	_	_	_	_	_
6	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	degraded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
14	set	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	agents	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	including	_	VERB	_	VerbForm=Ger	_	_	_	_
25	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
26	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
29	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	viral	_	ADJ	_	Degree=Pos	_	_	_	_
33	transactivators	_	NOUN	_	Number=Plur	_	_	_	_
34	such	_	ADJ	_	Degree=Pos	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	Tax	_	NOUN	_	Number=Sing	_	_	_	_
38	protein	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	human	_	ADJ	_	Degree=Pos	_	_	_	_
41	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
42	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
43	virus	_	NOUN	_	Number=Sing	_	_	_	_
44	type	_	NOUN	_	Number=Sing	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	explore	_	VERB	_	VerbForm=Inf	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	kappa	_	VERB	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	PROPN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	novel	_	NOUN	_	Number=Sing	_	_	_	_
21	mutants	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
24	kappa	_	VERB	_	Number=Sing	_	_	_	_
25	B	_	PROPN	_	Number=Sing	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	that	_	PRON	_	PronType=Rel	_	_	_	_
28	uncouple	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
30	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	signal	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	transducing	_	VERB	_	Degree=Pos	_	_	_	_
35	functions	_	NOUN	_	Number=Plur	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	human	_	ADJ	_	Degree=Pos	_	_	_	_
38	T	_	NOUN	_	Number=Sing	_	_	_	_
39	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Specifically	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	removal	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	N-	_	PROPN	_	Number=Sing	_	_	_	_
7	terminal	_	NOUN	_	Number=Sing	_	_	_	_
8	36	_	NUM	_	NumType=Card	_	_	_	_
9	amino	_	ADJ	_	Degree=Pos	_	_	_	_
10	acids	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	kappa	_	VERB	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	alpha	_	PROPN	_	Number=Sing	_	_	_	_
16	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	disrupt	_	VERB	_	VerbForm=Inf	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	ability	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	form	_	VERB	_	VerbForm=Inf	_	_	_	_
23	latent	_	ADJ	_	Number=Sing	_	_	_	_
24	complexes	_	NOUN	_	Number=Plur	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	deletion	_	NOUN	_	Number=Sing	_	_	_	_
5	mutation	_	NOUN	_	Number=Sing	_	_	_	_
6	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	degradative	_	ADJ	_	Degree=Pos	_	_	_	_
12	loss	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	functional	_	ADJ	_	Degree=Pos	_	_	_	_
16	release	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	kappa	_	PROPN	_	Number=Sing	_	_	_	_
20	B	_	PROPN	_	Number=Sing	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	PROPN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	Tax	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Alanine	_	ADJ	_	Number=Sing	_	_	_	_
2	substitutions	_	NOUN	_	Number=Plur	_	_	_	_
3	introduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	at	_	ADP	_	_	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	serine	_	NOUN	_	Number=Sing	_	_	_	_
7	residues	_	NOUN	_	Number=Plur	_	_	_	_
8	positioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	within	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	N	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	terminal	_	ADJ	_	Number=Sing	_	_	_	_
14	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	also	_	ADV	_	_	_	_	_	_
22	yielded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
24	repressors	_	NOUN	_	Number=Plur	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	escaped	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	Tax	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	turnover	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	that	_	DET	_	_	_	_	_	_
34	potently	_	ADV	_	_	_	_	_	_
35	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	immune	_	ADJ	_	Number=Sing	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	pathways	_	NOUN	_	Number=Plur	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappa	_	NOUN	_	Number=Sing	_	_	_	_
43	B	_	NOUN	_	Number=Sing	_	_	_	_
44	induction	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	including	_	VERB	_	VerbForm=Ger	_	_	_	_
47	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
48	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	from	_	ADP	_	_	_	_	_	_
50	antigen	_	NOUN	_	Number=Sing	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
53	receptors	_	NOUN	_	Number=Plur	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	introduction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	phosphoserine	_	NOUN	_	Number=Sing	_	_	_	_
8	mimetic	_	NOUN	_	Number=Sing	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	sites	_	NOUN	_	Number=Plur	_	_	_	_
12	rectified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	functional	_	ADJ	_	Degree=Pos	_	_	_	_
15	defect	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	finding	_	NOUN	_	Number=Sing	_	_	_	_
19	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	causal	_	ADJ	_	Degree=Pos	_	_	_	_
23	linkage	_	NOUN	_	Number=Sing	_	_	_	_
24	between	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
27	status	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
30	stability	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
34	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	vivo	_	NOUN	_	Number=Sing	_	_	_	_
6	studies	_	NOUN	_	Number=Plur	_	_	_	_
7	define	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	critical	_	ADJ	_	Degree=Pos	_	_	_	_
10	signal	_	ADJ	_	Number=Sing	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	domain	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	kappa	_	VERB	_	Number=Sing	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	coordinately	_	ADV	_	_	_	_	_	_
20	controls	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	biologic	_	ADJ	_	Number=Sing	_	_	_	_
23	activities	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
26	kappa	_	VERB	_	Number=Sing	_	_	_	_
27	B	_	PROPN	_	Number=Sing	_	_	_	_
28	alpha	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	PROPN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	response	_	NOUN	_	Number=Sing	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	viral	_	ADJ	_	Degree=Pos	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	immune	_	VERB	_	Degree=Pos	_	_	_	_
40	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001956	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	cloning	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	functional	_	ADJ	_	Degree=Pos	_	_	_	_
5	characterization	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	murine	_	NOUN	_	Number=Sing	_	_	_	_
8	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
9	encoding	_	VERB	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	NFATc	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	family	_	NOUN	_	Number=Sing	_	_	_	_
15	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	important	_	ADJ	_	Degree=Pos	_	_	_	_
17	roles	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	immune	_	ADJ	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	responses	_	NOUN	_	Number=Plur	_	_	_	_
23	by	_	SCONJ	_	_	_	_	_	_
24	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	genes	_	NOUN	_	Number=Plur	_	_	_	_
29	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
30	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	immunoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
33	proteins	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	cloning	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	characterization	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	full	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	length	_	NOUN	_	Number=Sing	_	_	_	_
11	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
12	encoding	_	VERB	_	Number=Sing	_	_	_	_
13	murine	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	m	_	NOUN	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	NFATc	_	NOUN	_	Number=Sing	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	predicts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	all	_	DET	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	structural	_	ADJ	_	Degree=Pos	_	_	_	_
28	motifs	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	NFAT	_	ADJ	_	Number=Sing	_	_	_	_
31	family	_	NOUN	_	Number=Sing	_	_	_	_
32	members	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	including	_	VERB	_	VerbForm=Ger	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	rel	_	NOUN	_	Number=Sing	_	_	_	_
37	homology	_	NOUN	_	Number=Sing	_	_	_	_
38	domain	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
42	homology	_	NOUN	_	Number=Sing	_	_	_	_
43	domain	_	NOUN	_	Number=Sing	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
47	translocation	_	NOUN	_	Number=Sing	_	_	_	_
48	signals	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	mNFATc	_	PROPN	_	Number=Sing	_	_	_	_
2	complexed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	bound	_	ADJ	_	Degree=Pos	_	_	_	_
8	specifically	_	ADV	_	_	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	murine	_	NOUN	_	Number=Sing	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	NFAT	_	NOUN	_	Degree=Pos	_	_	_	_
16	recognition	_	NOUN	_	Number=Sing	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	co	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	COS	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	7	_	NUM	_	NumType=Card	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	PROPN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
8	probe	_	NOUN	_	Number=Sing	_	_	_	_
9	hybridized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	4.5	_	NUM	_	NumType=Card	_	_	_	_
13	kb	_	NOUN	_	Number=Sing	_	_	_	_
14	transcript	_	NOUN	_	Number=Sing	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	highly	_	ADV	_	_	_	_	_	_
18	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	murine	_	ADJ	_	Number=Sing	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	Northern	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	situ	_	NOUN	_	Number=Sing	_	_	_	_
6	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	mNFATc	_	NOUN	_	Number=Sing	_	_	_	_
9	transcript	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	early	_	ADJ	_	Degree=Pos	_	_	_	_
15	stage	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	development	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	mouse	_	NOUN	_	Number=Sing	_	_	_	_
4	embryo	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	mNFATc	_	NOUN	_	Number=Sing	_	_	_	_
7	transcript	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	strongly	_	ADV	_	_	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	thymus	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	lung	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	submandibular	_	ADJ	_	Degree=Pos	_	_	_	_
17	gland	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	weakly	_	ADV	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	skeletal	_	ADJ	_	Degree=Pos	_	_	_	_
22	muscle	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	heart	_	NOUN	_	Number=Sing	_	_	_	_
25	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	mNFATc	_	NOUN	_	Number=Sing	_	_	_	_
28	may	_	AUX	_	VerbForm=Fin	_	_	_	_
29	have	_	VERB	_	VerbForm=Inf	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	role	_	NOUN	_	Number=Sing	_	_	_	_
32	both	_	CCONJ	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	embryogenesis	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	mature	_	ADJ	_	Degree=Pos	_	_	_	_
38	T	_	NOUN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001957	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
3	signal	_	NOUN	_	Number=Sing	_	_	_	_
4	transmission	_	NOUN	_	Number=Sing	_	_	_	_
5	pathways	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	complexes	_	NOUN	_	Number=Plur	_	_	_	_
13	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	between	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	immunophilin	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	either	_	CCONJ	_	_	_	_	_	_
19	FK506	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Proliferation	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	immunologic	_	ADJ	_	Degree=Pos	_	_	_	_
4	function	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	initiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	signals	_	NOUN	_	Number=Plur	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	antigen	_	NOUN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	immunosuppressant	_	ADJ	_	Number=Sing	_	_	_	_
22	FK506	_	NOUN	_	Number=Sing	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	structural	_	ADJ	_	Degree=Pos	_	_	_	_
28	analog	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	hand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	signals	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	not	_	ADV	_	_	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	FK506	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Remarkably	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	drugs	_	NOUN	_	Number=Plur	_	_	_	_
6	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	each	_	DET	_	_	_	_	_	_
8	other	_	ADJ	_	Degree=Pos	_	_	_	_
9	's	_	PART	_	_	_	_	_	_
10	actions	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	raising	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	possibility	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	PRON	_	_	_	_	_	_
16	both	_	DET	_	_	_	_	_	_
17	act	_	VERB	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	means	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	common	_	ADJ	_	Degree=Pos	_	_	_	_
23	immunophilin	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	immunosuppressant	_	ADJ	_	Degree=Pos	_	_	_	_
26	binding	_	VERB	_	Number=Sing	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
6	constant	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	FK506	_	NOUN	_	Number=Sing	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	FKBP	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	Kd	_	NOUN	_	Number=Sing	_	_	_	_
17	=	_	SYM	_	_	_	_	_	_
18	0.2	_	NUM	_	NumType=Card	_	_	_	_
19	nM	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	close	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
26	constant	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	FK506	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	FKBP	_	PROPN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	Kd	_	PROPN	_	Number=Sing	_	_	_	_
33	=	_	SYM	_	_	_	_	_	_
34	0.4	_	NUM	_	NumType=Card	_	_	_	_
35	nM	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
40	effective	_	ADJ	_	Degree=Pos	_	_	_	_
41	biologic	_	ADJ	_	Degree=Pos	_	_	_	_
42	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
43	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	excess	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	needed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	revert	_	VERB	_	VerbForm=Inf	_	_	_	_
11	FK506	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
14	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	production	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	AT	_	ADP	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	specific	_	ADJ	_	Degree=Pos	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	factor	_	NOUN	_	Number=Sing	_	_	_	_
37	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	gene	_	NOUN	_	Number=Sing	_	_	_	_
43	activation	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Similarly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	excess	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	FK506	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	needed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	revert	_	VERB	_	VerbForm=Inf	_	_	_	_
11	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
14	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	drug	_	NOUN	_	Number=Sing	_	_	_	_
3	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
4	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	antagonism	_	NOUN	_	Number=Sing	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	explained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	relative	_	ADJ	_	Degree=Pos	_	_	_	_
13	affinity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	drugs	_	NOUN	_	Number=Plur	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	abundance	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	immunophilin	_	NOUN	_	Number=Sing	_	_	_	_
27	FKBP	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	FKBP	_	PROPN	_	Number=Sing	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	catalyze	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	interconversion	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cis	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	trans	_	NOUN	_	Number=Plur	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	rotamers	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	peptidyl	_	ADJ	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	prolyl	_	NOUN	_	Number=Sing	_	_	_	_
22	amide	_	ADJ	_	Number=Sing	_	_	_	_
23	bond	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	peptide	_	NOUN	_	Number=Sing	_	_	_	_
26	substrates	_	NOUN	_	Number=Plur	_	_	_	_
27	;	_	PUNCT	_	_	_	_	_	_
28	here	_	ADV	_	PronType=Dem	_	_	_	_
29	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
30	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	like	_	ADP	_	_	_	_	_	_
35	FK506	_	PROPN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	potent	_	ADJ	_	Degree=Pos	_	_	_	_
40	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	rotamase	_	NOUN	_	Number=Sing	_	_	_	_
44	activity	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	FKBP	_	PROPN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	Ki	_	PROPN	_	Number=Sing	_	_	_	_
49	=	_	SYM	_	_	_	_	_	_
50	0.2	_	NUM	_	NumType=Card	_	_	_	_
51	nM	_	NOUN	_	Number=Sing	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Neither	_	CCONJ	_	_	_	_	_	_
2	FKBP	_	NOUN	_	Number=Sing	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	nor	_	CCONJ	_	_	_	_	_	_
5	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	rotamase	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	FKBP	_	PROPN	_	Number=Sing	_	_	_	_
11	alone	_	ADV	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	biologic	_	ADJ	_	Degree=Pos	_	_	_	_
18	actions	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	drugs	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Rather	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	findings	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	DET	_	_	_	_	_	_
7	immunophilin	_	ADJ	_	Number=Sing	_	_	_	_
8	bound	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	FK506	_	PROPN	_	Number=Sing	_	_	_	_
11	interferes	_	VERB	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	signals	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	while	_	SCONJ	_	_	_	_	_	_
20	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
21	bound	_	ADJ	_	Degree=Pos	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	immunophilin	_	NOUN	_	Number=Sing	_	_	_	_
25	interferes	_	VERB	_	Number=Plur	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	signals	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001966	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Signals	_	NOUN	_	Number=Plur	_	_	_	_
2	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	through	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	CD4	_	PROPN	_	Number=Sing	_	_	_	_
6	molecule	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	PROPN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	native	_	ADJ	_	Degree=Pos	_	_	_	_
6	envelope	_	NOUN	_	Number=Sing	_	_	_	_
7	glycoproteins	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	gp160	_	NOUN	_	Number=Sing	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	PROPN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	gp160	_	NOUN	_	Number=Sing	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	CD4	_	PROPN	_	Number=Sing	_	_	_	_
11	molecule	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	since	_	ADP	_	_	_	_	_	_
14	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
17	CD4	_	NOUN	_	Number=Sing	_	_	_	_
18	abrogates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	gp160	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	complex	_	NOUN	_	Number=Sing	_	_	_	_
10	consists	_	VERB	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	p65	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	p50	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	gp160	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	protein	_	VERB	_	Number=Sing	_	_	_	_
14	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
15	independent	_	ADJ	_	Degree=Pos	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	upon	_	ADP	_	_	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
22	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	abrogated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	C.	_	PROPN	_	Number=Sing	_	_	_	_
32	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	gp160	_	NUM	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	activation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	kappa	_	NOUN	_	Number=Sing	_	_	_	_
41	B	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	CD4	_	PROPN	_	Number=Sing	_	_	_	_
44	positive	_	ADJ	_	Degree=Pos	_	_	_	_
45	T	_	NOUN	_	Number=Sing	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	may	_	AUX	_	VerbForm=Fin	_	_	_	_
48	be	_	AUX	_	VerbForm=Inf	_	_	_	_
49	involved	_	ADJ	_	Degree=Pos	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	biological	_	ADJ	_	Degree=Pos	_	_	_	_
52	effects	_	NOUN	_	Number=Plur	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	e.g.	_	X	_	_	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
57	HIV	_	NOUN	_	Number=Sing	_	_	_	_
58	replication	_	NOUN	_	Number=Sing	_	_	_	_
59	,	_	PUNCT	_	_	_	_	_	_
60	hypergammaglobulinemia	_	NOUN	_	Number=Sing	_	_	_	_
61	,	_	PUNCT	_	_	_	_	_	_
62	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
63	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
64	secretion	_	NOUN	_	Number=Sing	_	_	_	_
65	,	_	PUNCT	_	_	_	_	_	_
66	hypercellularity	_	NOUN	_	Number=Sing	_	_	_	_
67	in	_	ADP	_	_	_	_	_	_
68	bone	_	NOUN	_	Number=Sing	_	_	_	_
69	marrow	_	NOUN	_	Number=Sing	_	_	_	_
70	and	_	CCONJ	_	_	_	_	_	_
71	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
72	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001967	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	different	_	ADJ	_	Degree=Pos	_	_	_	_
5	Jak	_	PROPN	_	Number=Sing	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	kinases	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	type	_	NOUN	_	Number=Sing	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	tax	_	NOUN	_	Number=Sing	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	virus	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	infection	_	NOUN	_	Number=Sing	_	_	_	_
5	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	adult	_	NOUN	_	Number=Sing	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	humans	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	viral	_	ADJ	_	Degree=Pos	_	_	_	_
3	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	tax	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	play	_	VERB	_	VerbForm=Inf	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	important	_	ADJ	_	Degree=Pos	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	oncogenesis	_	PROPN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	previous	_	ADJ	_	Degree=Pos	_	_	_	_
3	data	_	NOUN	_	Number=Sing	_	_	_	_
4	obtained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	tax	_	NOUN	_	Number=Sing	_	_	_	_
8	transgenic	_	NOUN	_	Number=Sing	_	_	_	_
9	mouse	_	NOUN	_	Number=Sing	_	_	_	_
10	model	_	NOUN	_	Number=Sing	_	_	_	_
11	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	tax	_	NOUN	_	Number=Sing	_	_	_	_
14	transforms	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	mouse	_	NOUN	_	Number=Sing	_	_	_	_
16	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	not	_	ADV	_	_	_	_	_	_
19	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	despite	_	ADP	_	_	_	_	_	_
22	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	tax	_	NOUN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	both	_	DET	_	_	_	_	_	_
29	tissues	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
3	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	130	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kD	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	s	_	X	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	tax	_	NOUN	_	Number=Sing	_	_	_	_
18	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	fibroblast	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	PROPN	_	Number=Sing	_	_	_	_
21	line	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
30	lines	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	but	_	CCONJ	_	_	_	_	_	_
33	not	_	PART	_	_	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
36	from	_	ADP	_	_	_	_	_	_
37	Thy	_	PRON	_	_	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	tax	_	NOUN	_	Number=Sing	_	_	_	_
40	transgenic	_	ADJ	_	Number=Sing	_	_	_	_
41	mice	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Phosphotyrosine	_	NOUN	_	Number=Sing	_	_	_	_
2	immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
3	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	Western	_	ADJ	_	Degree=Pos	_	_	_	_
6	blot	_	NOUN	_	Number=Sing	_	_	_	_
7	analysis	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	set	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Jak	_	PROPN	_	Number=Sing	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	p130	_	NOUN	_	Number=Sing	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	Jak2	_	PROPN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	tax	_	NOUN	_	Number=Sing	_	_	_	_
24	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	mouse	_	NOUN	_	Number=Sing	_	_	_	_
26	fibroblastic	_	ADJ	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	line	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	Jak3	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	human	_	ADJ	_	Degree=Pos	_	_	_	_
37	T	_	NOUN	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	lines	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Jak2	_	PROPN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	tax	_	NOUN	_	Number=Sing	_	_	_	_
6	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	high	_	ADJ	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Tyrosine	_	ADJ	_	Number=Sing	_	_	_	_
2	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	could	_	AUX	_	VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	Balb	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	c3T3	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	using	_	VERB	_	VerbForm=Ger	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	supernatant	_	NOUN	_	Number=Sing	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	line	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	induction	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	neutralizing	_	NOUN	_	VerbForm=Ger	_	_	_	_
12	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Jak	_	PROPN	_	Number=Sing	_	_	_	_
5	kinases	_	NOUN	_	Number=Plur	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	facilitate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	tumor	_	NOUN	_	Number=Sing	_	_	_	_
9	growth	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	transgenic	_	ADJ	_	Number=Sing	_	_	_	_
22	mouse	_	NOUN	_	Number=Sing	_	_	_	_
23	model	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001968	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	production	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	action	_	NOUN	_	Number=Sing	_	_	_	_
18	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	signal	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	downregulate	_	VERB	_	Degree=Pos	_	_	_	_
6	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	beta	_	NOUN	_	Number=Sing	_	_	_	_
10	production	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	different	_	ADJ	_	Degree=Pos	_	_	_	_
17	mechanims	_	NOUN	_	Number=Plur	_	_	_	_
18	:	_	PUNCT	_	_	_	_	_	_
19	direct	_	ADJ	_	Degree=Pos	_	_	_	_
20	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	destabilization	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	preformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	beta	_	NOUN	_	Number=Sing	_	_	_	_
34	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Now	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nature	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
13	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	signal	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
19	mechanims	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	preincubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	hour	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	then	_	ADV	_	PronType=Dem	_	_	_	_
13	stimulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	either	_	ADV	_	_	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
17	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
20	myristate	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
27	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	beta	_	NOUN	_	Number=Sing	_	_	_	_
36	protein	_	NOUN	_	Number=Sing	_	_	_	_
37	production	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	but	_	CCONJ	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
42	myristate	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	production	_	NOUN	_	Number=Sing	_	_	_	_
46	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
47	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	3	_	NUM	_	NumType=Card	_	_	_	_
49	-	_	SYM	_	_	_	_	_	_
50	10	_	NUM	_	NumType=Card	_	_	_	_
51	fold	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	difference	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
9	level	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	added	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cultures	_	NOUN	_	Number=Plur	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	hours	_	NOUN	_	Number=Plur	_	_	_	_
10	after	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	stimulators	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
15	clearly	_	ADV	_	_	_	_	_	_
16	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	beta	_	NOUN	_	Number=Sing	_	_	_	_
22	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	regardless	_	ADV	_	_	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	stimulator	_	NOUN	_	Number=Sing	_	_	_	_
28	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	although	_	SCONJ	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	effect	_	NOUN	_	Number=Sing	_	_	_	_
33	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
34	clearly	_	ADV	_	_	_	_	_	_
35	weaker	_	ADJ	_	Degree=Cmp	_	_	_	_
36	on	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	PMA	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	data	_	NOUN	_	Number=Sing	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
8	myristate	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	signal	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	prolonged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	C	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	?	_	PUNCT	_	_	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_

1	can	_	AUX	_	VerbForm=Fin	_	_	_	_
2	not	_	PART	_	_	_	_	_	_
3	be	_	AUX	_	VerbForm=Inf	_	_	_	_
4	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	prior	_	ADJ	_	Degree=Pos	_	_	_	_
7	incubation	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	protects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	induced	_	VERB	_	Degree=Pos	_	_	_	_
16	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	degradative	_	ADJ	_	Degree=Pos	_	_	_	_
20	action	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001970	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Heat	_	NOUN	_	Number=Sing	_	_	_	_
2	shock	_	NOUN	_	Number=Sing	_	_	_	_
3	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	replication	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	chronically	_	ADV	_	_	_	_	_	_
10	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	promyelocyte	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	line	_	NOUN	_	Number=Sing	_	_	_	_
14	OM10.1	_	NOUN	_	NumType=Card	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	long	_	ADJ	_	Degree=Pos	_	_	_	_
3	period	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
6	latency	_	NOUN	_	Number=Sing	_	_	_	_
7	before	_	ADP	_	_	_	_	_	_
8	development	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	symptoms	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	characteristic	_	ADJ	_	Degree=Pos	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	infection	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	OM10.1	_	NUM	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	promyelocyte	_	NOUN	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	line	_	NOUN	_	Number=Sing	_	_	_	_
7	latently	_	ADV	_	_	_	_	_	_
8	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	developed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	model	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	SCONJ	_	_	_	_	_	_
21	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	viral	_	ADJ	_	Degree=Pos	_	_	_	_
26	latency	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	virus	_	NOUN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	latently	_	ADV	_	_	_	_	_	_
6	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	line	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	heat	_	NOUN	_	Number=Sing	_	_	_	_
11	shock	_	NOUN	_	Number=Sing	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	42	_	NUM	_	NumType=Card	_	_	_	_
14	degrees	_	NOUN	_	Number=Plur	_	_	_	_
15	C	_	NOUN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	h	_	NOUN	_	Number=Plur	_	_	_	_
19	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	high	_	ADJ	_	Degree=Pos	_	_	_	_
23	level	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	production	_	NOUN	_	Number=Sing	_	_	_	_
29	without	_	ADP	_	_	_	_	_	_
30	addition	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	any	_	DET	_	_	_	_	_	_
33	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	SCONJ	_	_	_	_	_	_
8	using	_	VERB	_	VerbForm=Ger	_	_	_	_
9	anti-TNF	_	ADJ	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	antibody	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	various	_	ADJ	_	Degree=Pos	_	_	_	_
15	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	TNF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	level	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	culture	_	NOUN	_	Number=Sing	_	_	_	_
9	supernatants	_	NOUN	_	Number=Plur	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	below	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	ELISA	_	PROPN	_	Number=Sing	_	_	_	_
17	assay	_	NOUN	_	Number=Sing	_	_	_	_
18	system	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	addition	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	anti-TNF	_	ADJ	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	antibody	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	culture	_	NOUN	_	Number=Sing	_	_	_	_
28	medium	_	NOUN	_	Number=Sing	_	_	_	_
29	could	_	AUX	_	VerbForm=Fin	_	_	_	_
30	partially	_	ADV	_	_	_	_	_	_
31	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	heat	_	NOUN	_	Number=Sing	_	_	_	_
34	shock	_	NOUN	_	Number=Sing	_	_	_	_
35	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	HIV	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	production	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Staurosporine	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	PKC	_	PROPN	_	Number=Sing	_	_	_	_
4	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	pentoxifylline	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	Ro5-3335	_	NUM	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	Tat	_	NOUN	_	Number=Sing	_	_	_	_
23	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	also	_	ADV	_	_	_	_	_	_
26	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	significantly	_	ADV	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	heat	_	NOUN	_	Number=Sing	_	_	_	_
30	shock	_	NOUN	_	Number=Sing	_	_	_	_
31	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	virus	_	NOUN	_	Number=Sing	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	particular	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	staurosporine	_	NOUN	_	Number=Sing	_	_	_	_
5	achieved	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	approximately	_	ADV	_	_	_	_	_	_
7	90	_	NUM	_	NumType=Card	_	_	_	_
8	%	_	SYM	_	Number=Sing	_	_	_	_
9	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	antigen	_	NOUN	_	Degree=Pos	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	heat	_	NOUN	_	Number=Sing	_	_	_	_
19	shock	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	OM10.1	_	NUM	_	Number=Sing	_	_	_	_
23	at	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	non-toxic	_	ADJ	_	Degree=Pos	_	_	_	_
26	concentration	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	heat	_	NOUN	_	Number=Sing	_	_	_	_
11	shock	_	NOUN	_	Number=Sing	_	_	_	_
12	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
15	fully	_	ADV	_	_	_	_	_	_
16	elucidated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	yet	_	ADV	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	presumed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	PKC	_	PROPN	_	Number=Sing	_	_	_	_
23	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	important	_	ADJ	_	Degree=Pos	_	_	_	_
26	role	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	HIV	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	present	_	ADJ	_	Degree=Pos	_	_	_	_
5	observations	_	NOUN	_	Number=Plur	_	_	_	_
6	will	_	AUX	_	VerbForm=Fin	_	_	_	_
7	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	further	_	ADJ	_	Degree=Pos	_	_	_	_
10	insight	_	NOUN	_	Number=Sing	_	_	_	_
11	into	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	infections	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001975	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	SHP2	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
4	transmembrane	_	NOUN	_	Number=Sing	_	_	_	_
5	adaptor	_	NOUN	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	SIT	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	novel	_	NOUN	_	Number=Sing	_	_	_	_
13	disulfide	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	dimer	_	NOUN	_	Number=Sing	_	_	_	_
17	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	several	_	ADJ	_	Degree=Pos	_	_	_	_
5	low	_	ADJ	_	Degree=Pos	_	_	_	_
6	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
7	weight	_	NOUN	_	Number=Sing	_	_	_	_
8	transmembrane	_	NOUN	_	Number=Sing	_	_	_	_
9	adaptor	_	NOUN	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	recruit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	src	_	NOUN	_	Number=Sing	_	_	_	_
14	homology	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	SH	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	domain	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
23	molecules	_	NOUN	_	Number=Plur	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	membrane	_	NOUN	_	Number=Sing	_	_	_	_
28	via	_	ADP	_	_	_	_	_	_
29	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	signaling	_	NOUN	_	Number=Sing	_	_	_	_
33	motifs	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	novel	_	NOUN	_	Number=Sing	_	_	_	_
6	molecule	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	group	_	NOUN	_	Number=Sing	_	_	_	_
10	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	SIT	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	SHP2	_	NOUN	_	Number=Sing	_	_	_	_
14	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	transmembrane	_	NOUN	_	Number=Sing	_	_	_	_
16	adaptor	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	SIT	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	disulfide	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	homodimeric	_	ADJ	_	Degree=Pos	_	_	_	_
8	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
3	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	src	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	possibly	_	ADV	_	_	_	_	_	_
8	syk	_	VERB	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
11	kinases	_	NOUN	_	Number=Plur	_	_	_	_
12	SIT	_	PROPN	_	Number=Sing	_	_	_	_
13	recruits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	SH2	_	PROPN	_	Number=Sing	_	_	_	_
16	domain	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
20	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
21	SHP2	_	NOUN	_	Number=Sing	_	_	_	_
22	via	_	ADP	_	_	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	immunoreceptor	_	ADJ	_	Number=Sing	_	_	_	_
25	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
29	motif	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	SIT	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	downmodulates	_	VERB	_	_	_	_	_	_
8	T	_	NUM	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	phytohemagglutinin	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	AT	_	ADP	_	_	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	by	_	SCONJ	_	_	_	_	_	_
31	interfering	_	VERB	_	VerbForm=Ger	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	signaling	_	NOUN	_	Number=Sing	_	_	_	_
34	processes	_	NOUN	_	Number=Plur	_	_	_	_
35	that	_	PRON	_	PronType=Rel	_	_	_	_
36	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
37	probably	_	ADV	_	_	_	_	_	_
38	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	upstream	_	ADP	_	_	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	activation	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	phospholipase	_	NOUN	_	Number=Sing	_	_	_	_
44	C.	_	PROPN	_	Number=Sing	_	_	_	_
45	However	_	ADV	_	_	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	binding	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	SHP2	_	NOUN	_	Number=Sing	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	SIT	_	PROPN	_	Number=Sing	_	_	_	_
52	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
53	not	_	PART	_	_	_	_	_	_
54	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
55	for	_	ADP	_	_	_	_	_	_
56	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
57	of	_	ADP	_	_	_	_	_	_
58	NF	_	PROPN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	AT	_	ADP	_	_	_	_	_	_
61	induction	_	NOUN	_	Number=Sing	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
64	that	_	SCONJ	_	_	_	_	_	_
65	SIT	_	NOUN	_	Number=Sing	_	_	_	_
66	not	_	ADV	_	_	_	_	_	_
67	only	_	ADV	_	_	_	_	_	_
68	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
69	NF	_	PROPN	_	Number=Sing	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	AT	_	ADP	_	_	_	_	_	_
72	activity	_	NOUN	_	Number=Sing	_	_	_	_
73	but	_	CCONJ	_	_	_	_	_	_
74	also	_	ADV	_	_	_	_	_	_
75	controls	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
76	NF	_	PROPN	_	Number=Sing	_	_	_	_
77	-	_	PUNCT	_	_	_	_	_	_
78	AT	_	ADP	_	_	_	_	_	_
79	unrelated	_	ADJ	_	Degree=Pos	_	_	_	_
80	pathways	_	NOUN	_	Number=Plur	_	_	_	_
81	of	_	ADP	_	_	_	_	_	_
82	T	_	PROPN	_	Number=Sing	_	_	_	_
83	cell	_	NOUN	_	Number=Sing	_	_	_	_
84	activation	_	NOUN	_	Number=Sing	_	_	_	_
85	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
86	SHP2	_	NOUN	_	Number=Sing	_	_	_	_
87	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001977	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Thiol	_	PROPN	_	Number=Sing	_	_	_	_
2	modulation	_	NOUN	_	Number=Sing	_	_	_	_
3	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	-1	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	VERB	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	kinase	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B.	_	PROPN	_	Number=Sing	_	_	_	_
28	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	receptor	_	NOUN	_	Number=Sing	_	_	_	_
33	type	_	NOUN	_	Number=Sing	_	_	_	_
34	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1RI	_	PROPN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
42	with	_	ADP	_	_	_	_	_	_
43	other	_	ADJ	_	Degree=Pos	_	_	_	_
44	proteins	_	NOUN	_	Number=Plur	_	_	_	_
45	thus	_	ADV	_	_	_	_	_	_
46	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
47	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
48	complex	_	ADJ	_	Degree=Pos	_	_	_	_
49	system	_	NOUN	_	Number=Sing	_	_	_	_
50	by	_	ADP	_	_	_	_	_	_
51	which	_	PRON	_	PronType=Rel	_	_	_	_
52	IL	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	1	_	NUM	_	NumType=Card	_	_	_	_
55	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
56	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
57	various	_	ADJ	_	Degree=Pos	_	_	_	_
58	signals	_	NOUN	_	Number=Plur	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	initiating	_	NOUN	_	Number=Sing	_	_	_	_
3	event	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	still	_	ADV	_	_	_	_	_	_
6	uncertain	_	ADJ	_	Degree=Pos	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	recently	_	ADV	_	_	_	_	_	_
13	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	kinase	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	one	_	NUM	_	NumType=Card	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	earliest	_	ADJ	_	Degree=Sup	_	_	_	_
24	events	_	NOUN	_	Number=Plur	_	_	_	_
25	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	Martin	_	PROPN	_	Number=Sing	_	_	_	_
28	et	_	X	_	_	_	_	_	_
29	al	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_

1	Eur.J.Immunol.1994.24	_	NUM	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	1566	_	NUM	_	NumType=Card	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	signaling	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	commonly	_	ADV	_	_	_	_	_	_
7	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
10	processes	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	subject	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	redox	_	NOUN	_	Degree=Pos	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	whether	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1RI	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	could	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	target	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	redox	_	ADJ	_	Number=Sing	_	_	_	_
22	regulation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	whether	_	SCONJ	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	could	_	AUX	_	VerbForm=Fin	_	_	_	_
32	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	kappa	_	NOUN	_	Number=Sing	_	_	_	_
41	B	_	NOUN	_	Number=Sing	_	_	_	_
42	activation	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	murine	_	NOUN	_	Number=Sing	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	line	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	EL4	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	without	_	ADP	_	_	_	_	_	_
18	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	different	_	ADJ	_	Degree=Pos	_	_	_	_
21	compounds	_	NOUN	_	Number=Plur	_	_	_	_
22	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
27	redox	_	NOUN	_	Number=Sing	_	_	_	_
28	status	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Thiol	_	PROPN	_	Number=Sing	_	_	_	_
2	modifying	_	VERB	_	Number=Sing	_	_	_	_
3	agents	_	NOUN	_	Number=Plur	_	_	_	_
4	like	_	ADP	_	_	_	_	_	_
5	diamide	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	menadione	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	pyrrolidine	_	NOUN	_	Number=Sing	_	_	_	_
10	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	PDTC	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	diethyl	_	ADJ	_	Degree=Pos	_	_	_	_
16	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	phenylarsine	_	NOUN	_	Number=Sing	_	_	_	_
19	oxide	_	NOUN	_	Number=Sing	_	_	_	_
20	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1RI	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	kinase	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	N	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Acetylcysteine	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	'-	_	PUNCT	_	_	_	_	_	_
9	dipyridyl	_	ADJ	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	aminotriazole	_	NOUN	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	nitrofurantoin	_	NOUN	_	Number=Sing	_	_	_	_
14	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	show	_	VERB	_	VerbForm=Inf	_	_	_	_
17	any	_	DET	_	_	_	_	_	_
18	effect	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	reversible	_	ADJ	_	Degree=Pos	_	_	_	_
7	unless	_	SCONJ	_	_	_	_	_	_
8	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
9	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	buthionine	_	NOUN	_	Number=Sing	_	_	_	_
14	sulfoximine	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	conditions	_	NOUN	_	Number=Plur	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1RI	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	similarly	_	ADV	_	_	_	_	_	_
19	impaired	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	EL4	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	From	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	observations	_	NOUN	_	Number=Plur	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	free	_	ADJ	_	Degree=Pos	_	_	_	_
8	thiols	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1RI	_	PROPN	_	Number=Sing	_	_	_	_
14	complex	_	NOUN	_	Number=Sing	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	essential	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1RI	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	kinase	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	that	_	SCONJ	_	_	_	_	_	_
31	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
32	process	_	NOUN	_	Number=Sing	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	mandatory	_	ADJ	_	Degree=Pos	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	signaling	_	NOUN	_	Number=Sing	_	_	_	_
40	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	NF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	kappa	_	NOUN	_	Number=Sing	_	_	_	_
45	B	_	NOUN	_	Number=Sing	_	_	_	_
46	activation	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001988	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	atopic	_	ADJ	_	Number=Sing	_	_	_	_
12	diseases	_	NOUN	_	Number=Plur	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	study	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	allergen	_	ADJ	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	helper	_	NOUN	_	Number=Sing	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Cytokines	_	NOUN	_	Number=Plur	_	_	_	_
4	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	helper	_	NOUN	_	Number=Sing	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	intimately	_	ADV	_	_	_	_	_	_
11	involved	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
14	allergic	_	ADJ	_	Degree=Pos	_	_	_	_
15	diseases	_	NOUN	_	Number=Plur	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	eosinophilic	_	ADJ	_	Degree=Pos	_	_	_	_
19	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	OBJECTIVE	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	production	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	potent	_	ADJ	_	Degree=Pos	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	CD4	_	PROPN	_	Number=Sing	_	_	_	_
22	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	patients	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	asthma	_	NOUN	_	Number=Sing	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Allergen	_	ADJ	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_

1	T	_	NUM	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	clones	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	hybridomas	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	established	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
13	blood	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	patients	_	NOUN	_	Number=Plur	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	asthma	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	responses	_	NOUN	_	Number=Plur	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	various	_	ADJ	_	Degree=Pos	_	_	_	_
25	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	determined	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	nonspecific	_	ADJ	_	Degree=Pos	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	5	_	NUM	_	NumType=Card	_	_	_	_
8	production	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	CD4	_	PROPN	_	Number=Sing	_	_	_	_
11	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	atopic	_	ADJ	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	nonatopic	_	ADJ	_	Degree=Pos	_	_	_	_
8	subjects	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	asthma	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	significantly	_	ADV	_	_	_	_	_	_
13	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
21	controls	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
2	blood	_	NOUN	_	Number=Sing	_	_	_	_
3	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	atopic	_	ADJ	_	Degree=Pos	_	_	_	_
7	asthma	_	NOUN	_	Number=Sing	_	_	_	_
8	patients	_	NOUN	_	Number=Plur	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	proliferated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	5	_	NUM	_	NumType=Card	_	_	_	_
16	after	_	ADP	_	_	_	_	_	_
17	incubation	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	mite	_	NOUN	_	Number=Sing	_	_	_	_
20	allergen	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	mite	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	helper	_	NOUN	_	Number=Sing	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	involved	_	ADJ	_	Degree=Pos	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	eosinophilic	_	ADJ	_	Degree=Pos	_	_	_	_
35	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	atopic	_	ADJ	_	Degree=Pos	_	_	_	_
38	asthma	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
9	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	construct	_	NOUN	_	Number=Sing	_	_	_	_
12	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	into	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	5	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	clones	_	NOUN	_	Number=Plur	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	clearly	_	ADV	_	_	_	_	_	_
24	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	after	_	ADP	_	_	_	_	_	_
26	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	515	_	NUM	_	NumType=Card	_	_	_	_
32	base	_	NOUN	_	Number=Sing	_	_	_	_
33	pair	_	NOUN	_	Number=Sing	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	5	_	NUM	_	NumType=Card	_	_	_	_
37	gene	_	NOUN	_	Number=Sing	_	_	_	_
38	segment	_	NOUN	_	Number=Sing	_	_	_	_
39	upstream	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	coding	_	NOUN	_	Number=Sing	_	_	_	_
43	region	_	NOUN	_	Number=Sing	_	_	_	_
44	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
45	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
46	to	_	PART	_	_	_	_	_	_
47	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
48	to	_	ADP	_	_	_	_	_	_
49	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
50	signals	_	NOUN	_	Number=Plur	_	_	_	_
51	in	_	ADP	_	_	_	_	_	_
52	human	_	ADJ	_	Degree=Pos	_	_	_	_
53	helper	_	NOUN	_	Number=Sing	_	_	_	_
54	T	_	NOUN	_	Number=Sing	_	_	_	_
55	cells	_	NOUN	_	Number=Plur	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	same	_	ADJ	_	Degree=Pos	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	segment	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	5	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	nonproducing	_	VERB	_	NumType=Card	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	clones	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	5	_	NUM	_	NumType=Card	_	_	_	_
26	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	at	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
32	level	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Experiments	_	NOUN	_	Number=Plur	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	T	_	DET	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	hybridomas	_	NOUN	_	Number=Plur	_	_	_	_
6	confirmed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	findings	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	unique	_	ADJ	_	Degree=Pos	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	essential	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	IL	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	5	_	NUM	_	NumType=Card	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSION	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	5	_	NUM	_	NumType=Card	_	_	_	_
7	production	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	helper	_	NOUN	_	Number=Sing	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	cause	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	eosinophilic	_	ADJ	_	Degree=Pos	_	_	_	_
17	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	atopic	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	nonatopic	_	ADJ	_	Degree=Pos	_	_	_	_
23	asthma	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Elucidation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	5-specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	facilitate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	development	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	novel	_	NOUN	_	Number=Sing	_	_	_	_
14	treatments	_	NOUN	_	Number=Plur	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	allergic	_	ADJ	_	Degree=Pos	_	_	_	_
17	diseases	_	NOUN	_	Number=Plur	_	_	_	_
18	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	eosinophilic	_	ADJ	_	Degree=Pos	_	_	_	_
21	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	003001990	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Renal	_	ADJ	_	Degree=Pos	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	carcinoma-	_	NOUN	_	Number=Sing	_	_	_	_
4	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	gangliosides	_	NOUN	_	Number=Plur	_	_	_	_
6	suppress	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	impaired	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	patients	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	renal	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	carcinomas	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	RCCs	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	SCONJ	_	_	_	_	_	_
2	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	subset	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	patients	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	RCCs	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	suppression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	stimulus	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	degradation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
5	products	_	NOUN	_	Number=Plur	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	cultured	_	VERB	_	Degree=Pos	_	_	_	_
8	RCC	_	PROPN	_	Number=Sing	_	_	_	_
9	explants	_	NOUN	_	Number=Plur	_	_	_	_
10	inhibit	_	VERB	_	Number=Sing	_	_	_	_
11	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
18	volunteers	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	despite	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	normal	_	ADJ	_	Degree=Pos	_	_	_	_
23	level	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	stimulus	_	ADJ	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
29	degradation	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
3	agent	_	NOUN	_	Number=Sing	_	_	_	_
4	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	several	_	ADJ	_	Degree=Pos	_	_	_	_
6	features	_	NOUN	_	Number=Plur	_	_	_	_
7	characteristic	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	ganglioside	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	including	_	VERB	_	VerbForm=Ger	_	_	_	_
13	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	neuraminidase	_	NOUN	_	Number=Sing	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	protease	_	VERB	_	VerbForm=Inf	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	;	_	PUNCT	_	_	_	_	_	_
21	hydrophobicity	_	NOUN	_	Number=Sing	_	_	_	_
22	;	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
25	weight	_	NOUN	_	Number=Sing	_	_	_	_
26	less	_	ADJ	_	Degree=Cmp	_	_	_	_
27	than	_	ADP	_	_	_	_	_	_
28	3	_	NUM	_	NumType=Card	_	_	_	_
29	kDa	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Indeed	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	detected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	gangliosides	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	supernatants	_	NOUN	_	Number=Plur	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	RCC	_	PROPN	_	Number=Sing	_	_	_	_
10	explants	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	not	_	ADV	_	_	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
15	normal	_	ADJ	_	Degree=Pos	_	_	_	_
16	kidney	_	NOUN	_	Number=Sing	_	_	_	_
17	tissue	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Gangliosides	_	NOUN	_	Number=Plur	_	_	_	_
2	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	RCC	_	PROPN	_	Number=Sing	_	_	_	_
5	supernatants	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	as	_	ADV	_	_	_	_	_	_
8	well	_	ADV	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	purified	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
12	bovine	_	NOUN	_	Number=Sing	_	_	_	_
13	gangliosides	_	NOUN	_	Number=Sing	_	_	_	_
14	G	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	m1	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	G	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	d1a	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
26	binding	_	VERB	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	T	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	IFN	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	gamma	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	findings	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	tumor	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	gangliosides	_	NOUN	_	Number=Plur	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	blunt	_	VERB	_	VerbForm=Inf	_	_	_	_
14	antitumor	_	NOUN	_	Number=Sing	_	_	_	_
15	immune	_	NOUN	_	Number=Sing	_	_	_	_
16	responses	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	patients	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	RCCs	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011000	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	3	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	deazaadenosine	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	S	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	adenosylhomocysteine	_	NOUN	_	Number=Sing	_	_	_	_
9	hydrolase	_	NOUN	_	Number=Sing	_	_	_	_
10	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	dual	_	ADJ	_	Degree=Pos	_	_	_	_
14	effects	_	NOUN	_	Number=Plur	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	promotion	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
12	degradation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Previously	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	deazaadenosine	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	DZA	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	potent	_	NOUN	_	Degree=Pos	_	_	_	_
14	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	substrate	_	VERB	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	S	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	adenosylhomocysteine	_	ADJ	_	Degree=Pos	_	_	_	_
21	hydrolase	_	NOUN	_	Number=Sing	_	_	_	_
22	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
23	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
24	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	tumor	_	NOUN	_	Number=Sing	_	_	_	_
30	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1beta	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	mouse	_	NOUN	_	Number=Sing	_	_	_	_
40	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
41	RAW	_	PROPN	_	Number=Sing	_	_	_	_
42	264.7	_	NUM	_	NumType=Card	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	effects	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	DZA	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	regulation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	DZA	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	through	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	hindrance	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	p65	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	Rel	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	A	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
21	without	_	ADP	_	_	_	_	_	_
22	reduction	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	translocation	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	DNA	_	NOUN	_	Number=Sing	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	DZA	_	PROPN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	potentiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	addition	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	homocysteine	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	DZA	_	PROPN	_	Number=Sing	_	_	_	_
5	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
8	degradation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	IkappaBbeta	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	increase	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	DNA	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	VERB	_	Number=Sing	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	absence	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
36	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
37	activity	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	RAW	_	PROPN	_	Number=Sing	_	_	_	_
40	264.7	_	NUM	_	NumType=Card	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	reduction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	DZA	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	neither	_	CCONJ	_	_	_	_	_	_
9	involved	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	complex	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	nor	_	CCONJ	_	_	_	_	_	_
16	modulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	addition	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	homocysteine	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	strongly	_	ADV	_	_	_	_	_	_
4	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	DZA	_	PROPN	_	Number=Sing	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	potent	_	NOUN	_	Degree=Pos	_	_	_	_
11	drug	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	treatment	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	diseases	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
22	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	central	_	ADJ	_	Degree=Pos	_	_	_	_
25	pathogenic	_	ADJ	_	Degree=Pos	_	_	_	_
26	role	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	as	_	ADV	_	_	_	_	_	_
29	well	_	ADV	_	Degree=Pos	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	useful	_	ADJ	_	Degree=Pos	_	_	_	_
33	tool	_	NOUN	_	Number=Sing	_	_	_	_
34	for	_	SCONJ	_	_	_	_	_	_
35	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	regulation	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
40	functions	_	NOUN	_	Number=Plur	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	NF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011002	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inducible	_	ADJ	_	Degree=Pos	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	c	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	fos	_	ADP	_	_	_	_	_	_
8	serum	_	NOUN	_	Number=Sing	_	_	_	_
9	response	_	NOUN	_	Number=Sing	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	phosphotyrosine	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	proto	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
5	c	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	fos	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	early	_	ADJ	_	Degree=Pos	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	one	_	NUM	_	NumType=Card	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	transcribed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	after	_	ADP	_	_	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	most	_	ADJ	_	Degree=Sup	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	variety	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	ligands	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Fos	_	PROPN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	may	_	AUX	_	VerbForm=Fin	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	pivotal	_	ADJ	_	Degree=Pos	_	_	_	_
7	event	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	converting	_	VERB	_	VerbForm=Ger	_	_	_	_
10	ligand	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	interactions	_	NOUN	_	Number=Plur	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	membrane	_	NOUN	_	Number=Sing	_	_	_	_
17	into	_	ADP	_	_	_	_	_	_
18	functional	_	ADJ	_	Degree=Pos	_	_	_	_
19	modulation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	serum	_	NOUN	_	Number=Sing	_	_	_	_
3	response	_	NOUN	_	Number=Sing	_	_	_	_
4	element	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	SRE	_	X	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	participates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	various	_	ADJ	_	Degree=Pos	_	_	_	_
20	growth	_	NOUN	_	Number=Sing	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
25	esters	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
28	squelching	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	complex	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	Band	_	NOUN	_	Number=Sing	_	_	_	_
10	A	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	SRE	_	VERB	_	VerbForm=Inf	_	_	_	_
15	DNA	_	NOUN	_	Number=Sing	_	_	_	_
16	within	_	ADP	_	_	_	_	_	_
17	10	_	NUM	_	NumType=Card	_	_	_	_
18	min	_	NOUN	_	Number=Plur	_	_	_	_
19	after	_	ADP	_	_	_	_	_	_
20	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
21	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	PBL	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	becomes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	nondetectable	_	ADJ	_	Degree=Pos	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	60	_	NUM	_	NumType=Card	_	_	_	_
33	min	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Band	_	NOUN	_	Number=Sing	_	_	_	_
2	A	_	PROPN	_	Number=Sing	_	_	_	_
3	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	serum	_	NOUN	_	Number=Sing	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	plus	_	CCONJ	_	_	_	_	_	_
9	additional	_	ADJ	_	Degree=Pos	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	s	_	X	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	PRON	_	PronType=Rel	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
9	residue	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	SCONJ	_	_	_	_	_	_
11	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	PBL	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	component	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	Band	_	NOUN	_	Number=Sing	_	_	_	_
22	A	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	SRE	_	NOUN	_	Number=Sing	_	_	_	_
26	motif	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	no	_	ADV	_	_	_	_	_	_
10	longer	_	ADV	_	Degree=Cmp	_	_	_	_
11	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	DNA	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	Band	_	NOUN	_	Number=Sing	_	_	_	_
17	A	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	suppression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	restored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	within	_	ADP	_	_	_	_	_	_
26	30	_	NUM	_	NumType=Card	_	_	_	_
27	min	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	phosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
3	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
4	residue	_	NOUN	_	Number=Sing	_	_	_	_
5	itself	_	PRON	_	Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	important	_	ADJ	_	Degree=Pos	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	interaction	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011007	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Rel	_	PROPN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	trigger	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Notch	_	NOUN	_	Number=Sing	_	_	_	_
10	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
11	pathway	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Jagged1	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	ligand	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	Notch	_	NOUN	_	Number=Sing	_	_	_	_
23	receptors	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Jagged1	_	PROPN	_	Number=Sing	_	_	_	_
2	belongs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	DSL	_	NOUN	_	Number=Sing	_	_	_	_
6	family	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	ligands	_	NOUN	_	Number=Plur	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	Notch	_	NOUN	_	Number=Sing	_	_	_	_
11	receptors	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	various	_	ADJ	_	Degree=Pos	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	lineages	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	little	_	ADV	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	about	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factors	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	Jagged1	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	Rel	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	RelA	_	PROPN	_	Number=Sing	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	jagged1	_	VERB	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	whereas	_	SCONJ	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	mutant	_	NOUN	_	Number=Sing	_	_	_	_
13	defective	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
16	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Importantly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	jagged1	_	VERB	_	Number=Sing	_	_	_	_
4	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	upregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	effect	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
22	mutant	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
28	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	surface	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Jagged1	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	monolayers	_	NOUN	_	Number=Plur	_	_	_	_
12	led	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	functional	_	ADJ	_	Degree=Pos	_	_	_	_
16	interaction	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	Notch1	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	TAN	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	correlated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	initiation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	SCONJ	_	_	_	_	_	_
7	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
8	downstream	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Notch	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	as	_	SCONJ	_	_	_	_	_	_
13	evidenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	levels	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	HES	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	co-cultivated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	CD23	_	NOUN	_	Number=Sing	_	_	_	_
29	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	co-cultivated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
4	Rel	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	Jagged1	_	PROPN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	highly	_	ADV	_	_	_	_	_	_
19	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	splenic	_	ADJ	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	where	_	ADV	_	PronType=Rel	_	_	_	_
25	c	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	Rel	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	constitutively	_	ADV	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	trigger	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Notch	_	NOUN	_	Number=Sing	_	_	_	_
10	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
11	pathway	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	neighboring	_	VERB	_	VerbForm=Ger	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	by	_	SCONJ	_	_	_	_	_	_
16	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	jagged1	_	ADJ	_	Degree=Pos	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	suggest	_	VERB	_	VerbForm=Inf	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	role	_	NOUN	_	Number=Sing	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	Jagged1	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	function	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	highlight	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	potential	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	interplay	_	NOUN	_	Number=Sing	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	Notch	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	signaling	_	NOUN	_	Number=Sing	_	_	_	_
18	pathways	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	immune	_	NOUN	_	Number=Sing	_	_	_	_
22	system	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011012	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	AP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	activates	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	LTR	_	PROPN	_	Number=Sing	_	_	_	_
6	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	three	_	NUM	_	NumType=Card	_	_	_	_
8	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	elements	_	NOUN	_	Number=Plur	_	_	_	_
11	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	21	_	NUM	_	NumType=Card	_	_	_	_
14	base	_	NOUN	_	Number=Sing	_	_	_	_
15	pair	_	NOUN	_	Number=Sing	_	_	_	_
16	repeats	_	NOUN	_	Number=Plur	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	tax	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Mutagenesis	_	PROPN	_	Number=Sing	_	_	_	_
2	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	21	_	NUM	_	NumType=Card	_	_	_	_
6	bp	_	NOUN	_	Number=Sing	_	_	_	_
7	repeats	_	NOUN	_	Number=Plur	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	subdivided	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	into	_	ADP	_	_	_	_	_	_
12	three	_	NUM	_	NumType=Card	_	_	_	_
13	motifs	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	A	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	C	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	each	_	DET	_	_	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Int	_	_	_	_
24	influences	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	level	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	tax	_	NOUN	_	Number=Sing	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	site	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	21	_	NUM	_	NumType=Card	_	_	_	_
7	bp	_	NOUN	_	Number=Sing	_	_	_	_
8	repeat	_	NOUN	_	Number=Sing	_	_	_	_
9	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	strong	_	ADJ	_	Degree=Pos	_	_	_	_
11	homology	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	previously	_	ADV	_	_	_	_	_	_
14	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	AP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	present	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	T-lymphocytes	_	PROPN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	that	_	DET	_	_	_	_	_	_
14	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	non-transformed	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	T-lymphocytes	_	PROPN	_	Number=Plur	_	_	_	_
22	specifically	_	ADV	_	_	_	_	_	_
23	bound	_	ADJ	_	Degree=Pos	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	consensus	_	NOUN	_	Number=Sing	_	_	_	_
27	motif	_	NOUN	_	Number=Sing	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	AP	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	each	_	DET	_	_	_	_	_	_
34	21	_	NUM	_	NumType=Card	_	_	_	_
35	bp	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	AP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	LTR	_	VERB	_	_	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
22	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	AP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	DNA	_	PROPN	_	Number=Sing	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	transient	_	ADJ	_	Degree=Pos	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	assays	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	retardation	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	methylation	_	NOUN	_	Number=Sing	_	_	_	_
5	interference	_	NOUN	_	Number=Sing	_	_	_	_
6	studies	_	NOUN	_	Number=Plur	_	_	_	_
7	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	bacterially	_	ADV	_	_	_	_	_	_
10	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	bound	_	ADJ	_	Degree=Pos	_	_	_	_
15	specifically	_	ADV	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	high	_	ADJ	_	Degree=Pos	_	_	_	_
19	affinity	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	all	_	DET	_	_	_	_	_	_
22	three	_	NUM	_	NumType=Card	_	_	_	_
23	21	_	NUM	_	NumType=Card	_	_	_	_
24	bp	_	NOUN	_	Number=Sing	_	_	_	_
25	repeats	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
30	required	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	core	_	NOUN	_	Number=Sing	_	_	_	_
33	sequence	_	NOUN	_	Number=Sing	_	_	_	_
34	AGGC	_	NOUN	_	Number=Sing	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	specific	_	ADJ	_	Degree=Pos	_	_	_	_
37	binding	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	AP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	members	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	CREB	_	PROPN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	ATF	_	PROPN	_	Number=Sing	_	_	_	_
17	family	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
21	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	motif	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	21	_	NUM	_	NumType=Card	_	_	_	_
26	bp	_	NOUN	_	Number=Sing	_	_	_	_
27	repeat	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Transfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	construct	_	VERB	_	Number=Sing	_	_	_	_
9	into	_	ADP	_	_	_	_	_	_
10	T-lymphocytes	_	PROPN	_	Number=Sing	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	LTR	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADV	_	_	_	_	_	_
2	least	_	ADV	_	Degree=Sup	_	_	_	_
3	two	_	NUM	_	NumType=Card	_	_	_	_
4	21	_	NUM	_	NumType=Card	_	_	_	_
5	bp	_	NOUN	_	Number=Sing	_	_	_	_
6	repeats	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	high	_	ADJ	_	Degree=Pos	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	AP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	consensus	_	NOUN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	sequences	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	21	_	NUM	_	NumType=Card	_	_	_	_
30	bp	_	NOUN	_	Number=Sing	_	_	_	_
31	repeats	_	NOUN	_	Number=Plur	_	_	_	_
32	eliminate	_	VERB	_	VerbForm=Inf	_	_	_	_
33	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	0030011018	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
9	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
10	microE5	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	motif	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Activity	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
5	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	light	_	NOUN	_	Number=Sing	_	_	_	_
9	chain	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
12	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	complex	_	ADJ	_	Degree=Pos	_	_	_	_
16	interplay	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	developmentally	_	ADV	_	_	_	_	_	_
21	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	complementary	_	ADJ	_	Degree=Pos	_	_	_	_
3	DNAs	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	encode	_	NOUN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	denoted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	ITF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	ITF	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	variety	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	types	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	microE5	_	NOUN	_	Number=Sing	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	motif	_	NOUN	_	Number=Sing	_	_	_	_
36	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	both	_	CCONJ	_	_	_	_	_	_
39	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	kappa	_	NOUN	_	Number=Sing	_	_	_	_
42	light	_	NOUN	_	Number=Sing	_	_	_	_
43	chain	_	NOUN	_	Number=Sing	_	_	_	_
44	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	complementary	_	ADJ	_	Degree=Pos	_	_	_	_
3	DNAs	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	products	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	yet	_	CCONJ	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	ITF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	ITF	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	structurally	_	ADV	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	functionally	_	ADV	_	_	_	_	_	_
24	similar	_	ADJ	_	Degree=Pos	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	one	_	NUM	_	NumType=Card	_	_	_	_
7	another	_	DET	_	_	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	putative	_	ADJ	_	Degree=Pos	_	_	_	_
11	helix	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	loop	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	helix	_	NOUN	_	Number=Sing	_	_	_	_
16	motifs	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	each	_	DET	_	_	_	_	_	_
19	possesses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
22	domain	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	dictates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011024	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interaction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	sickle	_	NOUN	_	Degree=Pos	_	_	_	_
4	erythrocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	presence	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	conditioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	medium	_	ADJ	_	Number=Sing	_	_	_	_
16	induces	_	NOUN	_	Number=Plur	_	_	_	_
17	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
18	stress	_	NOUN	_	Number=Sing	_	_	_	_
19	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	transendothelial	_	ADJ	_	Degree=Pos	_	_	_	_
22	migration	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
3	adherence	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	sickle	_	ADJ	_	Degree=Pos	_	_	_	_
6	red	_	ADJ	_	Degree=Pos	_	_	_	_
7	blood	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	SS	_	NOUN	_	Number=Sing	_	_	_	_
11	RBC	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
18	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
23	occlusion	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	major	_	ADJ	_	Degree=Pos	_	_	_	_
27	cause	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	morbidity	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	sickle	_	NOUN	_	Degree=Pos	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	disease	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	SCD	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	determined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	interaction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	SS	_	NOUN	_	Number=Sing	_	_	_	_
8	RBC	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
16	stress	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	would	_	AUX	_	VerbForm=Fin	_	_	_	_
19	culminate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
25	molecules	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	CAMs	_	NOUN	_	Number=Plur	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	involved	_	ADJ	_	Degree=Pos	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	diapedesis	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	adherence	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	SS	_	NOUN	_	Number=Sing	_	_	_	_
42	reticulocytes	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	interaction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	SS	_	PROPN	_	Number=Sing	_	_	_	_
8	RBC	_	PROPN	_	Number=Sing	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	%	_	SYM	_	Number=Sing	_	_	_	_
12	concentration	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	presence	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	multimers	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	von	_	NOUN	_	Number=Sing	_	_	_	_
20	Willebrand	_	PROPN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	vWf	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	conditioned	_	ADJ	_	Degree=Pos	_	_	_	_
33	medium	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	E	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	CM	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	cultured	_	VERB	_	Degree=Pos	_	_	_	_
41	human	_	ADJ	_	Degree=Pos	_	_	_	_
42	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
43	vein	_	NOUN	_	Number=Sing	_	_	_	_
44	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	HUVEC	_	NOUN	_	Number=Sing	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	in	_	ADP	_	_	_	_	_	_
52	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
53	fivefold	_	NOUN	_	Number=Sing	_	_	_	_
54	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
55	formation	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	thiobarbituric	_	ADJ	_	Degree=Pos	_	_	_	_
58	acid	_	NOUN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
61	substances	_	NOUN	_	Number=Plur	_	_	_	_
62	(	_	PUNCT	_	_	_	_	_	_
63	TBARS	_	NOUN	_	Number=Sing	_	_	_	_
64	)	_	PUNCT	_	_	_	_	_	_
65	and	_	CCONJ	_	_	_	_	_	_
66	activation	_	NOUN	_	Number=Sing	_	_	_	_
67	of	_	ADP	_	_	_	_	_	_
68	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
69	transcription	_	NOUN	_	Number=Sing	_	_	_	_
70	factor	_	NOUN	_	Number=Sing	_	_	_	_
71	NF	_	NOUN	_	Number=Sing	_	_	_	_
72	-	_	PUNCT	_	_	_	_	_	_
73	kB	_	NOUN	_	Number=Sing	_	_	_	_
74	,	_	PUNCT	_	_	_	_	_	_
75	both	_	CCONJ	_	_	_	_	_	_
76	indicators	_	NOUN	_	Number=Plur	_	_	_	_
77	of	_	ADP	_	_	_	_	_	_
78	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
79	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
80	stress	_	NOUN	_	Number=Sing	_	_	_	_
81	.	_	PUNCT	_	_	_	_	_	_

1	Normal	_	ADJ	_	Degree=Pos	_	_	_	_
2	RBC	_	NOUN	_	Number=Sing	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	none	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	phenomena	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
3	stress	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	signaling	_	NOUN	_	Number=Sing	_	_	_	_
7	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	surface	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	subset	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	CAMs	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	E-	_	PUNCT	_	Number=Sing	_	_	_	_
24	selectin	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	HUVEC	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
5	radical	_	ADJ	_	Degree=Pos	_	_	_	_
6	scavenger	_	NOUN	_	Number=Sing	_	_	_	_
7	enzymes	_	NOUN	_	Number=Plur	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	catalase	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	superoxide	_	NOUN	_	Number=Sing	_	_	_	_
12	dismutase	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	probucol	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	events	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	preincubation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	HUVEC	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
9	peptide	_	NOUN	_	Number=Sing	_	_	_	_
10	Arg	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Gly	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	Asp	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	RGD	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	vWf	_	ADP	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
23	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	SS	_	PROPN	_	Number=Sing	_	_	_	_
26	RBC	_	PROPN	_	Number=Sing	_	_	_	_
27	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	surface	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kB	_	NOUN	_	Number=Sing	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	SS	_	PROPN	_	Number=Sing	_	_	_	_
4	RBC	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
8	stress	_	NOUN	_	Number=Sing	_	_	_	_
9	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	twofold	_	NOUN	_	Number=Sing	_	_	_	_
13	increase	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transendothelial	_	ADJ	_	Number=Sing	_	_	_	_
17	migration	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	like	_	ADP	_	_	_	_	_	_
23	HL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	60	_	NUM	_	NumType=Card	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
30	blood	_	NOUN	_	Number=Sing	_	_	_	_
31	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	approximately	_	ADV	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	sixfold	_	NOUN	_	Tense=Past|VerbForm=Part	_	_	_	_
37	increase	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	platelet	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
44	molecule	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	PECAM	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	1	_	NUM	_	NumType=Card	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	each	_	DET	_	_	_	_	_	_
55	of	_	ADP	_	_	_	_	_	_
56	which	_	PRON	_	PronType=Rel	_	_	_	_
57	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
58	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
59	by	_	ADP	_	_	_	_	_	_
60	protein	_	NOUN	_	Number=Sing	_	_	_	_
61	kinase	_	NOUN	_	Number=Sing	_	_	_	_
62	C	_	NOUN	_	Number=Sing	_	_	_	_
63	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
64	and	_	CCONJ	_	_	_	_	_	_
65	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	adherence	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	contact	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	SS	_	NOUN	_	Number=Sing	_	_	_	_
11	RBC	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	large	_	ADJ	_	Degree=Pos	_	_	_	_
17	vessel	_	NOUN	_	Number=Sing	_	_	_	_
18	can	_	AUX	_	VerbForm=Fin	_	_	_	_
19	generate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
22	stress	_	NOUN	_	Number=Sing	_	_	_	_
23	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	diapedesis	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	as	_	ADV	_	_	_	_	_	_
33	well	_	ADV	_	Degree=Pos	_	_	_	_
34	as	_	ADP	_	_	_	_	_	_
35	heightened	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	adherence	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	SS	_	NOUN	_	Number=Sing	_	_	_	_
39	reticulocytes	_	NOUN	_	Number=Plur	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
42	that	_	SCONJ	_	_	_	_	_	_
43	injury	_	NOUN	_	Number=Sing	_	_	_	_
44	/	_	PUNCT	_	_	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
48	can	_	AUX	_	VerbForm=Fin	_	_	_	_
49	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	vaso	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	occlusion	_	NOUN	_	Number=Sing	_	_	_	_
54	in	_	ADP	_	_	_	_	_	_
55	SCD	_	PROPN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011026	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
3	signalling	_	NOUN	_	Number=Sing	_	_	_	_
4	pathways	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	involved	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	control	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
13	junB	_	NOUN	_	Number=Sing	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	6	_	NUM	_	NumType=Card	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	hybridoma	_	NOUN	_	Number=Sing	_	_	_	_
25	7TD1	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	level	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	junB	_	NOUN	_	Number=Sing	_	_	_	_
8	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	hybridoma	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	line	_	NOUN	_	Number=Sing	_	_	_	_
15	7TD1	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	under	_	ADP	_	_	_	_	_	_
18	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	6	_	NUM	_	NumType=Card	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	6	_	NUM	_	NumType=Card	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	6	_	NUM	_	NumType=Card	_	_	_	_
4	increases	_	NOUN	_	Number=Plur	_	_	_	_
5	junB	_	NOUN	_	Number=Sing	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
10	fashion	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	early	_	ADV	_	Degree=Pos	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	peak	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	transient	_	ADJ	_	Degree=Pos	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	likely	_	ADJ	_	Degree=Pos	_	_	_	_
11	corresponds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	well	_	ADV	_	Degree=Pos	_	_	_	_
15	documented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	typical	_	ADJ	_	Degree=Pos	_	_	_	_
17	junB	_	NOUN	_	Number=Sing	_	_	_	_
18	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	numerous	_	ADJ	_	Degree=Pos	_	_	_	_
25	growth	_	NOUN	_	Number=Sing	_	_	_	_
26	factors	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	including	_	VERB	_	VerbForm=Ger	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	6	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	variance	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	peak	_	NOUN	_	Number=Sing	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	never	_	ADV	_	_	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	previously	_	ADV	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	lasted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	several	_	ADJ	_	Degree=Pos	_	_	_	_
16	hours	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	consequence	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	junB	_	NOUN	_	Number=Sing	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	stimulated	_	VERB	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
19	fashion	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	JunB	_	PROPN	_	Number=Sing	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	occurred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	exclusively	_	ADV	_	_	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	level	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	bimodal	_	ADJ	_	Degree=Pos	_	_	_	_
22	increase	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	junB	_	NOUN	_	Number=Sing	_	_	_	_
25	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	JunB	_	PROPN	_	Number=Sing	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	can	_	AUX	_	VerbForm=Fin	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	accounted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
36	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	junB	_	NOUN	_	Number=Sing	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	point	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	major	_	ADJ	_	Degree=Pos	_	_	_	_
9	differences	_	NOUN	_	Number=Plur	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	control	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	early	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	late	_	ADJ	_	Degree=Pos	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	6	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	junB	_	NOUN	_	Number=Sing	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	waves	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	First	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
4	strongly	_	ADV	_	_	_	_	_	_
5	potentiated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
11	wave	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	whereas	_	SCONJ	_	_	_	_	_	_
14	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
15	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	early	_	ADJ	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	burst	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Second	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	tyrphostin	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	impaired	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	not	_	ADV	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
20	junB	_	NOUN	_	Number=Sing	_	_	_	_
21	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
22	peak	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Conversely	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	genistein	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	another	_	DET	_	_	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	totally	_	ADV	_	_	_	_	_	_
11	abolished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
17	peak	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	junB	_	NOUN	_	Number=Sing	_	_	_	_
20	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
21	whereas	_	SCONJ	_	_	_	_	_	_
22	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
23	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
31	peak	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Altogether	_	ADV	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	data	_	NOUN	_	Number=Sing	_	_	_	_
4	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	7TD1	_	NUM	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	controls	_	NOUN	_	Number=Plur	_	_	_	_
15	junB	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
20	fashion	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	means	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	two	_	NUM	_	NumType=Card	_	_	_	_
25	separate	_	ADJ	_	Degree=Pos	_	_	_	_
26	transduction	_	NOUN	_	Number=Sing	_	_	_	_
27	pathways	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011027	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	IFN	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	priming	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
7	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	LPS	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	TNF	_	NOUN	_	Number=Sing	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	augmenting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	MRNA	_	PROPN	_	Number=Sing	_	_	_	_
19	stability	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
12	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	critical	_	ADJ	_	Degree=Pos	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	highly	_	ADV	_	_	_	_	_	_
20	regulated	_	VERB	_	Degree=Pos	_	_	_	_
21	host	_	NOUN	_	Number=Sing	_	_	_	_
22	defence	_	NOUN	_	Number=Sing	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	augmentation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	LPS	_	NOUN	_	Number=Sing	_	_	_	_
5	responses	_	NOUN	_	Number=Plur	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	interferon	_	NOUN	_	Number=Sing	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	IFN	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	gamma	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	referred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	priming	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	well	_	ADV	_	Degree=Pos	_	_	_	_
22	established	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	s	_	X	_	_	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	which	_	DET	_	PronType=Int	_	_	_	_
10	priming	_	VERB	_	Number=Sing	_	_	_	_
11	occurs	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	poorly	_	ADV	_	_	_	_	_	_
14	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	tumour	_	NOUN	_	Number=Sing	_	_	_	_
3	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	TNF	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	induction	_	NOUN	_	Number=Sing	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	model	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	experiments	_	NOUN	_	Number=Plur	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	designed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	analyse	_	VERB	_	VerbForm=Inf	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	detail	_	NOUN	_	Number=Sing	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	priming	_	ADJ	_	VerbForm=Ger	_	_	_	_
22	effect	_	NOUN	_	Number=Sing	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	LPS	_	NOUN	_	Number=Sing	_	_	_	_
26	response	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Priming	_	VERB	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	IFN	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	gamma	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	primarily	_	ADV	_	_	_	_	_	_
8	manifested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	level	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	TNF	_	PROPN	_	Number=Sing	_	_	_	_
14	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
15	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	IFN	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	pre	_	X	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	treatment	_	NOUN	_	Number=Sing	_	_	_	_
7	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
10	rather	_	ADV	_	_	_	_	_	_
11	than	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	LPS	_	NOUN	_	Number=Sing	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Priming	_	NOUN	_	Number=Sing	_	_	_	_
2	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	after	_	ADP	_	_	_	_	_	_
4	several	_	ADJ	_	Degree=Pos	_	_	_	_
5	hours	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	treatment	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	primed	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
12	state	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	either	_	CCONJ	_	_	_	_	_	_
17	IFN	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	gamma	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	GM	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	CSF	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	not	_	ADV	_	_	_	_	_	_
27	M	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	CSF	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Primed	_	ADJ	_	Degree=Pos	_	_	_	_
2	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	transcribed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
9	rate	_	NOUN	_	Number=Sing	_	_	_	_
10	than	_	ADP	_	_	_	_	_	_
11	freshly	_	ADV	_	_	_	_	_	_
12	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	upon	_	ADP	_	_	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	LPS	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
4	rate	_	NOUN	_	Number=Sing	_	_	_	_
5	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	increase	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	as	_	SCONJ	_	_	_	_	_	_
21	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
24	mobility	_	NOUN	_	Number=Sing	_	_	_	_
25	shift	_	NOUN	_	Number=Sing	_	_	_	_
26	assay	_	NOUN	_	Number=Sing	_	_	_	_
27	using	_	VERB	_	VerbForm=Ger	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	consensus	_	NOUN	_	Number=Sing	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	additional	_	ADJ	_	Degree=Pos	_	_	_	_
3	significant	_	ADJ	_	Degree=Pos	_	_	_	_
4	finding	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	than	_	ADP	_	_	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	primed	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	much	_	ADV	_	_	_	_	_	_
15	more	_	ADV	_	_	_	_	_	_
16	stable	_	ADJ	_	Degree=Pos	_	_	_	_
17	than	_	ADP	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	unprimed	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	T1	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	6	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	SYM	_	_	_	_	_	_
28	8	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	fold	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
6	stability	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	duration	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
12	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	longer	_	ADV	_	Degree=Cmp	_	_	_	_
15	following	_	VERB	_	VerbForm=Ger	_	_	_	_
16	LPS	_	NOUN	_	Number=Sing	_	_	_	_
17	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	primed	_	ADJ	_	Degree=Pos	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	addition	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	being	_	AUX	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
28	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	primed	_	ADJ	_	Degree=Pos	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	unprimed	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	possessed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	differential	_	ADJ	_	Degree=Pos	_	_	_	_
10	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
15	H-89	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	H-89	_	NUM	_	NumType=Card	_	_	_	_
2	substantially	_	ADV	_	_	_	_	_	_
3	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	LPS	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
9	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	unprimed	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	no	_	DET	_	_	_	_	_	_
17	effect	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	primed	_	ADJ	_	Degree=Pos	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	following	_	VERB	_	VerbForm=Ger	_	_	_	_
22	LPS	_	NOUN	_	Number=Sing	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	0030011029	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Platelet	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	PAF	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	positively	_	ADV	_	_	_	_	_	_
9	auto	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	PAF	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	transcript	_	NOUN	_	Number=Sing	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	type	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	through	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	PROPN	_	Number=Sing	_	_	_	_
29	B	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	platelet	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	PAFR	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
17	promoters	_	NOUN	_	Number=Plur	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	generate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	two	_	NUM	_	NumType=Card	_	_	_	_
28	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	as	_	ADP	_	_	_	_	_	_
32	PAFR	_	NOUN	_	Number=Sing	_	_	_	_
33	transcript	_	NOUN	_	Number=Sing	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	PAFR	_	NOUN	_	Number=Sing	_	_	_	_
37	transcript	_	NOUN	_	Number=Sing	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	though	_	SCONJ	_	_	_	_	_	_
42	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
43	open	_	ADJ	_	Degree=Pos	_	_	_	_
44	reading	_	NOUN	_	Number=Sing	_	_	_	_
45	frames	_	NOUN	_	Number=Plur	_	_	_	_
46	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
47	identical	_	ADJ	_	Degree=Pos	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	primer	_	ADJ	_	Degree=Pos	_	_	_	_
3	extension	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	discriminate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	PAFR	_	NOUN	_	Number=Sing	_	_	_	_
17	transcript	_	NOUN	_	Number=Sing	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	not	_	ADV	_	_	_	_	_	_
27	PAFR	_	NOUN	_	Number=Sing	_	_	_	_
28	transcript	_	NOUN	_	Number=Sing	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	tissue	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	type	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
37	upregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	PAF	_	NOUN	_	Number=Sing	_	_	_	_
40	as	_	ADV	_	_	_	_	_	_
41	well	_	ADV	_	Degree=Pos	_	_	_	_
42	as	_	ADP	_	_	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	13	_	NUM	_	NumType=Card	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	acetate	_	NOUN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	TPA	_	NOUN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	human	_	ADJ	_	Degree=Pos	_	_	_	_
55	stomach	_	NOUN	_	Number=Sing	_	_	_	_
56	cancer	_	NOUN	_	Number=Sing	_	_	_	_
57	cell	_	NOUN	_	Number=Sing	_	_	_	_
58	line	_	NOUN	_	Number=Sing	_	_	_	_
59	(	_	PUNCT	_	_	_	_	_	_
60	JR	_	PROPN	_	Number=Sing	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	St	_	PROPN	_	Number=Sing	_	_	_	_
63	cells	_	NOUN	_	Number=Plur	_	_	_	_
64	)	_	PUNCT	_	_	_	_	_	_
65	which	_	PRON	_	PronType=Rel	_	_	_	_
66	expresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
67	both	_	CCONJ	_	_	_	_	_	_
68	functional	_	ADJ	_	Degree=Pos	_	_	_	_
69	PAFR	_	NOUN	_	Number=Sing	_	_	_	_
70	transcript	_	NOUN	_	Number=Sing	_	_	_	_
71	1	_	NUM	_	NumType=Card	_	_	_	_
72	and	_	CCONJ	_	_	_	_	_	_
73	PAFR	_	NOUN	_	Number=Sing	_	_	_	_
74	transcript	_	NOUN	_	Number=Sing	_	_	_	_
75	2	_	NUM	_	NumType=Card	_	_	_	_
76	endogenously	_	ADV	_	_	_	_	_	_
77	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	transient	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	assay	_	NOUN	_	Number=Sing	_	_	_	_
12	using	_	VERB	_	VerbForm=Ger	_	_	_	_
13	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
14	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	CAT	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	reporter	_	NOUN	_	Number=Sing	_	_	_	_
22	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	both	_	CCONJ	_	_	_	_	_	_
25	PAF	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	TPA	_	PROPN	_	Number=Sing	_	_	_	_
28	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	but	_	CCONJ	_	_	_	_	_	_
33	not	_	ADV	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	three	_	NUM	_	NumType=Card	_	_	_	_
40	consensus	_	NOUN	_	Number=Sing	_	_	_	_
41	binding	_	VERB	_	Number=Sing	_	_	_	_
42	sites	_	NOUN	_	Number=Plur	_	_	_	_
43	for	_	ADP	_	_	_	_	_	_
44	NF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	kappa	_	PROPN	_	Number=Sing	_	_	_	_
47	B	_	PROPN	_	Number=Sing	_	_	_	_
48	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	from	_	ADP	_	_	_	_	_	_
50	-	_	SYM	_	_	_	_	_	_
51	571	_	NUM	_	NumType=Card	_	_	_	_
52	bp	_	NOUN	_	Number=Sing	_	_	_	_
53	to	_	ADP	_	_	_	_	_	_
54	-	_	SYM	_	_	_	_	_	_
55	459	_	NUM	_	NumType=Card	_	_	_	_
56	bp	_	PROPN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	positive	_	ADJ	_	Degree=Pos	_	_	_	_
9	regulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	PAFR	_	NOUN	_	Degree=Pos	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	PAF	_	NOUN	_	Number=Sing	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	possibly	_	ADV	_	_	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	reaction	_	NOUN	_	Number=Sing	_	_	_	_
8	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	kinase	_	NOUN	_	Number=Sing	_	_	_	_
11	C	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	PAF	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011031	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Immunosuppression	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_
5	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	through	_	ADP	_	_	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	VERB	_	Number=Sing	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
19	[	_	PUNCT	_	_	_	_	_	_
20	see	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
21	comments	_	NOUN	_	Number=Plur	_	_	_	_
22	]	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	among	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	most	_	ADV	_	_	_	_	_	_
6	potent	_	ADJ	_	Degree=Pos	_	_	_	_
7	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
10	agents	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	almost	_	ADV	_	_	_	_	_	_
6	all	_	DET	_	_	_	_	_	_
7	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	several	_	ADJ	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	surface	_	NOUN	_	Number=Sing	_	_	_	_
14	molecules	_	NOUN	_	Number=Plur	_	_	_	_
15	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	immune	_	ADJ	_	Degree=Pos	_	_	_	_
18	function	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
23	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
28	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	potent	_	ADJ	_	Degree=Pos	_	_	_	_
9	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	NF	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	mice	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	cultured	_	VERB	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	I	_	PRON	_	Number=Sing	_	_	_	_
10	kappa	_	VERB	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	traps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
25	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
26	complexes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	PROPN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	many	_	ADJ	_	Degree=Pos	_	_	_	_
8	immunoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	pro-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	can	_	AUX	_	VerbForm=Fin	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	major	_	ADJ	_	Degree=Pos	_	_	_	_
25	component	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011033	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Calcium	_	NOUN	_	Number=Sing	_	_	_	_
2	signalling	_	VERB	_	VerbForm=Ger	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	cyclophilin	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	immunosuppressant	_	ADJ	_	Degree=Pos	_	_	_	_
3	drug	_	NOUN	_	Number=Sing	_	_	_	_
4	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
5	A	_	NOUN	_	Number=Sing	_	_	_	_
6	blocks	_	NOUN	_	Number=Plur	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	calcium	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	signal	_	NOUN	_	Number=Sing	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	TCR	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	normally	_	ADV	_	_	_	_	_	_
21	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	bound	_	ADJ	_	Degree=Pos	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	cyclophilin	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	cyclosporin	_	VERB	_	Number=Sing	_	_	_	_
7	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	binds	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	inactivates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	key	_	ADJ	_	Degree=Pos	_	_	_	_
13	signalling	_	VERB	_	VerbForm=Ger	_	_	_	_
14	intermediate	_	ADJ	_	Degree=Pos	_	_	_	_
15	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
3	potential	_	ADJ	_	Degree=Pos	_	_	_	_
4	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	homologues	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
8	A	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	might	_	AUX	_	VerbForm=Fin	_	_	_	_
11	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	calcium	_	NOUN	_	Number=Sing	_	_	_	_
13	signalling	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
21	cyclophilin	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	proteins	_	NOUN	_	Number=Plur	_	_	_	_
27	using	_	VERB	_	VerbForm=Ger	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	yeast	_	ADJ	_	Number=Sing	_	_	_	_
30	two	_	NUM	_	NumType=Card	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
33	system	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	product	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	when	_	ADV	_	PronType=Int	_	_	_	_
6	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	specifically	_	ADV	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	by	_	SCONJ	_	_	_	_	_	_
23	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	factors	_	NOUN	_	Number=Plur	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	AT	_	ADP	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	IL2A	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	termed	_	VERB	_	Degree=Pos	_	_	_	_
5	calcium	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	signal	_	NOUN	_	Number=Sing	_	_	_	_
8	modulating	_	VERB	_	Number=Sing	_	_	_	_
9	cyclophilin	_	NOUN	_	Number=Sing	_	_	_	_
10	ligand	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	CAML	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	downstream	_	ADV	_	Degree=Pos	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	TCR	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	upstream	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	SCONJ	_	_	_	_	_	_
25	causing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	influx	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	calcium	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	CAML	_	PROPN	_	Number=Sing	_	_	_	_
2	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	new	_	ADJ	_	Degree=Pos	_	_	_	_
7	participant	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	calcium	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	signal	_	NOUN	_	Number=Sing	_	_	_	_
13	transduction	_	NOUN	_	Number=Sing	_	_	_	_
14	pathway	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	implicating	_	VERB	_	VerbForm=Ger	_	_	_	_
17	cyclophilin	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	calcium	_	NOUN	_	Number=Sing	_	_	_	_
21	signalling	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	even	_	ADV	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	absence	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011036	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	defensin	_	ADJ	_	Degree=Pos	_	_	_	_
4	resistance	_	NOUN	_	Number=Sing	_	_	_	_
5	phenotypes	_	NOUN	_	Number=Plur	_	_	_	_
6	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	mutations	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	phoP	_	NOUN	_	Number=Sing	_	_	_	_
12	virulence	_	NOUN	_	Number=Sing	_	_	_	_
13	regulon	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	Salmonella	_	PROPN	_	Number=Sing	_	_	_	_
16	typhimurium	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	defensin	_	NOUN	_	Number=Sing	_	_	_	_
3	sensitivities	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Salmonella	_	PROPN	_	Number=Sing	_	_	_	_
6	typhimurium	_	NOUN	_	Number=Sing	_	_	_	_
7	strains	_	NOUN	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	mutations	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	phoP	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	phoQ	_	NOUN	_	Number=Sing	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	component	_	ADJ	_	Degree=Pos	_	_	_	_
18	virulence	_	NOUN	_	Number=Sing	_	_	_	_
19	regulon	_	NOUN	_	Number=Sing	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	tested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	SCONJ	_	_	_	_	_	_
23	using	_	VERB	_	VerbForm=Ger	_	_	_	_
24	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	defensins	_	NOUN	_	Number=Plur	_	_	_	_
26	NP	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	NP	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Strains	_	NOUN	_	Number=Plur	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	mutations	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	either	_	CCONJ	_	_	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	pair	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	phoP	_	NOUN	_	Number=Sing	_	_	_	_
13	[	_	PUNCT	_	_	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	activator	_	NOUN	_	Number=Sing	_	_	_	_
16	]	_	PUNCT	_	_	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	phoQ	_	NOUN	_	Number=Sing	_	_	_	_
19	[	_	PUNCT	_	_	_	_	_	_
20	membrane	_	NOUN	_	Number=Sing	_	_	_	_
21	sensor	_	NOUN	_	Number=Sing	_	_	_	_
22	kinase	_	NOUN	_	Number=Sing	_	_	_	_
23	]	_	PUNCT	_	_	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	sensitivities	_	NOUN	_	Number=Plur	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	defensin	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	predicted	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
3	periplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
4	domain	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	PhoQ	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	markedly	_	ADV	_	_	_	_	_	_
12	anionic	_	ADJ	_	Degree=Pos	_	_	_	_
13	domain	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	could	_	AUX	_	VerbForm=Fin	_	_	_	_
16	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	cationic	_	ADJ	_	Degree=Pos	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
22	could	_	AUX	_	VerbForm=Fin	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	resistance	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	defensin	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	insertion	_	NOUN	_	Number=Sing	_	_	_	_
3	mutations	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	phoP	_	NOUN	_	Number=Sing	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	polar	_	ADJ	_	Degree=Pos	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	phoQ	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	constructed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	strains	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	PhoQ	_	NOUN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	absence	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	PhoP	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	test	_	VERB	_	Number=Sing	_	_	_	_
26	whether	_	SCONJ	_	_	_	_	_	_
27	resistance	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	defensin	_	NOUN	_	Number=Sing	_	_	_	_
30	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	only	_	ADV	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	phoQ	_	NOUN	_	Degree=Pos	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	product	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	resistance	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	defensin	_	NOUN	_	Number=Sing	_	_	_	_
7	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	function	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	both	_	DET	_	_	_	_	_	_
12	components	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	system	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	because	_	SCONJ	_	_	_	_	_	_
19	strains	_	NOUN	_	Number=Plur	_	_	_	_
20	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	PhoQ	_	NOUN	_	Number=Sing	_	_	_	_
22	without	_	ADP	_	_	_	_	_	_
23	PhoP	_	NOUN	_	Number=Sing	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	still	_	ADV	_	_	_	_	_	_
26	markedly	_	ADV	_	_	_	_	_	_
27	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	defensins	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	implied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	pag	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	phoP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	product	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	defensin	_	NOUN	_	Number=Sing	_	_	_	_
17	resistance	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	ability	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	defensins	_	NOUN	_	Number=Plur	_	_	_	_
9	NP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	NP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	5	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	HNP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	pag	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	peptides	_	NOUN	_	Number=Plur	_	_	_	_
30	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	no	_	DET	_	_	_	_	_	_
32	effect	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Defensin	_	PROPN	_	Degree=Pos	_	_	_	_
2	resistance	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	only	_	ADJ	_	Degree=Pos	_	_	_	_
7	virulence	_	NOUN	_	Number=Sing	_	_	_	_
8	characteristic	_	NOUN	_	Number=Sing	_	_	_	_
9	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	PhoP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	PhoQ	_	NOUN	_	Number=Sing	_	_	_	_
15	regulon	_	NOUN	_	Number=Sing	_	_	_	_
16	because	_	SCONJ	_	_	_	_	_	_
17	mutations	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	pagC	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	as	_	ADV	_	_	_	_	_	_
22	well	_	ADV	_	Degree=Pos	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	ones	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	phoP	_	NOUN	_	Number=Sing	_	_	_	_
28	locus	_	NOUN	_	Number=Sing	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
33	pag	_	NOUN	_	Number=Sing	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
37	PhoPc	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	no	_	DET	_	_	_	_	_	_
42	effect	_	NOUN	_	Number=Sing	_	_	_	_
43	on	_	ADP	_	_	_	_	_	_
44	defensin	_	NOUN	_	Number=Sing	_	_	_	_
45	resistance	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	even	_	ADV	_	_	_	_	_	_
48	though	_	SCONJ	_	_	_	_	_	_
49	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
50	rendered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	organism	_	NOUN	_	Number=Sing	_	_	_	_
53	avirulent	_	ADJ	_	Degree=Pos	_	_	_	_
54	and	_	CCONJ	_	_	_	_	_	_
55	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
56	in	_	ADP	_	_	_	_	_	_
57	survival	_	NOUN	_	Number=Sing	_	_	_	_
58	within	_	ADP	_	_	_	_	_	_
59	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	virulence	_	NOUN	_	Number=Sing	_	_	_	_
3	defect	_	NOUN	_	Number=Sing	_	_	_	_
4	conferred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	mutations	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	phoP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	phoQ	_	NOUN	_	Number=Sing	_	_	_	_
12	two	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	component	_	ADJ	_	Number=Sing	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	system	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	completely	_	ADV	_	_	_	_	_	_
20	explained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	alterations	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	resistance	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	cationic	_	ADJ	_	Degree=Pos	_	_	_	_
27	proteins	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	control	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	other	_	ADJ	_	Degree=Pos	_	_	_	_
34	proteins	_	NOUN	_	Number=Plur	_	_	_	_
35	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	S.	_	PROPN	_	Number=Sing	_	_	_	_
38	typhimurium	_	NOUN	_	Number=Sing	_	_	_	_
39	survival	_	NOUN	_	Number=Sing	_	_	_	_
40	within	_	ADP	_	_	_	_	_	_
41	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011040	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	AP	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	mature	_	ADJ	_	Degree=Pos	_	_	_	_
7	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	astrocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	preferentially	_	ADV	_	_	_	_	_	_
11	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	promoter	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	central	_	ADJ	_	Degree=Pos	_	_	_	_
19	21	_	NUM	_	NumType=Card	_	_	_	_
20	bp	_	PROPN	_	Number=Sing	_	_	_	_
21	repeat	_	VERB	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	lymphotropic	_	ADJ	_	Degree=Pos	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	type	_	NOUN	_	Number=Sing	_	_	_	_
16	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	long	_	ADJ	_	Degree=Pos	_	_	_	_
23	terminal	_	NOUN	_	Number=Sing	_	_	_	_
24	repeat	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	LTR	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	essential	_	ADJ	_	Degree=Pos	_	_	_	_
30	to	_	SCONJ	_	_	_	_	_	_
31	dissecting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
34	involved	_	ADJ	_	Degree=Pos	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	viral	_	ADJ	_	Degree=Pos	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	that	_	PRON	_	PronType=Rel	_	_	_	_
39	may	_	AUX	_	VerbForm=Fin	_	_	_	_
40	be	_	AUX	_	VerbForm=Inf	_	_	_	_
41	pertinent	_	ADJ	_	Degree=Pos	_	_	_	_
42	to	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	oncogenic	_	ADJ	_	Degree=Pos	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	neuropathogenic	_	ADJ	_	Degree=Pos	_	_	_	_
47	processes	_	NOUN	_	Number=Plur	_	_	_	_
48	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	with	_	ADP	_	_	_	_	_	_
50	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
53	infection	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
54	in	_	ADP	_	_	_	_	_	_
55	both	_	CCONJ	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	immune	_	NOUN	_	Number=Sing	_	_	_	_
58	and	_	CCONJ	_	_	_	_	_	_
59	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
60	systems	_	NOUN	_	Number=Plur	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	EMS	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	analyses	_	NOUN	_	Number=Plur	_	_	_	_
8	utilizing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
10	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	each	_	DET	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	21	_	NUM	_	NumType=Card	_	_	_	_
16	bp	_	NOUN	_	Number=Sing	_	_	_	_
17	repeat	_	ADJ	_	Degree=Pos	_	_	_	_
18	elements	_	NOUN	_	Number=Plur	_	_	_	_
19	reacted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	extracts	_	NOUN	_	Number=Plur	_	_	_	_
23	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	lines	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	lymphocytic	_	ADJ	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	neuronal	_	ADJ	_	Degree=Pos	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	glial	_	ADJ	_	Degree=Pos	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	origin	_	NOUN	_	Number=Sing	_	_	_	_
38	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	differential	_	ADJ	_	Degree=Pos	_	_	_	_
41	binding	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
44	factors	_	NOUN	_	Number=Plur	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	three	_	NUM	_	NumType=Card	_	_	_	_
48	21	_	NUM	_	NumType=Card	_	_	_	_
49	bp	_	NOUN	_	Number=Sing	_	_	_	_
50	repeats	_	NOUN	_	Number=Plur	_	_	_	_
51	(	_	PUNCT	_	_	_	_	_	_
52	1	_	NUM	_	NumType=Card	_	_	_	_
53	-	_	SYM	_	_	_	_	_	_
54	4	_	NUM	_	NumType=Card	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	ATF	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	CREB	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Sp	_	PROPN	_	Number=Sing	_	_	_	_
6	family	_	NOUN	_	Number=Sing	_	_	_	_
7	members	_	NOUN	_	Number=Plur	_	_	_	_
8	interacted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	21	_	NUM	_	NumType=Card	_	_	_	_
12	bp	_	NOUN	_	Number=Sing	_	_	_	_
13	repeats	_	VERB	_	Number=Plur	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	form	_	VERB	_	VerbForm=Inf	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	complexes	_	NOUN	_	Number=Plur	_	_	_	_
20	common	_	ADJ	_	Degree=Pos	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	all	_	DET	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	types	_	NOUN	_	Number=Plur	_	_	_	_
25	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	unique	_	ADJ	_	Degree=Pos	_	_	_	_
5	DNA	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	complex	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	when	_	ADV	_	PronType=Int	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	central	_	ADJ	_	Number=Sing	_	_	_	_
15	21	_	NUM	_	NumType=Card	_	_	_	_
16	bp	_	PROPN	_	Number=Sing	_	_	_	_
17	repeat	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	reacted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	extracts	_	NOUN	_	Number=Plur	_	_	_	_
23	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	either	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	U	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	373	_	NUM	_	NumType=Card	_	_	_	_
30	MG	_	PROPN	_	Number=Sing	_	_	_	_
31	glioblastoma	_	NOUN	_	Number=Sing	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	line	_	NOUN	_	Number=Sing	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	THP	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	mature	_	ADJ	_	Degree=Pos	_	_	_	_
40	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	line	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
4	sequence	_	NOUN	_	Number=Sing	_	_	_	_
5	requirements	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	immunoreactivity	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	DNA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	complex	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	comprised	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	AP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	components	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	Fos	_	PROPN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	Jun	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011041	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Histamine	_	PROPN	_	Number=Sing	_	_	_	_
2	modulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	c	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	fos	_	NOUN	_	Number=Sing	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	cyclic	_	ADJ	_	Number=Sing	_	_	_	_
11	AMP	_	NOUN	_	Number=Sing	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	via	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	H2	_	NOUN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	line	_	NOUN	_	Number=Sing	_	_	_	_
23	U937	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	histamine	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
9	agonists	_	NOUN	_	Number=Plur	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	c-myc	_	ADJ	_	Number=Sing	_	_	_	_
18	proto	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transcriptional	_	ADJ	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	translational	_	ADJ	_	Degree=Pos	_	_	_	_
26	levels	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	promonocytic	_	ADJ	_	Number=Sing	_	_	_	_
31	U937	_	NOUN	_	Number=Sing	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	line	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Histamine	_	PROPN	_	Number=Sing	_	_	_	_
2	transiently	_	ADV	_	_	_	_	_	_
3	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	c	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	fos	_	ADP	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	through	_	ADP	_	_	_	_	_	_
11	H2	_	NUM	_	Number=Sing	_	_	_	_
12	receptors	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Dibutyryl	_	PROPN	_	Number=Sing	_	_	_	_
2	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	elevated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
14	even	_	ADV	_	_	_	_	_	_
15	after	_	ADP	_	_	_	_	_	_
16	12	_	NUM	_	NumType=Card	_	_	_	_
17	hr	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Dose	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependence	_	NOUN	_	Number=Sing	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	using	_	VERB	_	VerbForm=Ger	_	_	_	_
6	histamine	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	dimaprit	_	NOUN	_	Number=Sing	_	_	_	_
9	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	EC50	_	NOUN	_	Number=Sing	_	_	_	_
13	values	_	NOUN	_	Number=Plur	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	c	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	fos	_	NOUN	_	Number=Sing	_	_	_	_
21	increase	_	NOUN	_	Number=Sing	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	similar	_	ADJ	_	Degree=Pos	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
28	might	_	AUX	_	VerbForm=Fin	_	_	_	_
29	be	_	AUX	_	VerbForm=Inf	_	_	_	_
30	involved	_	ADJ	_	Degree=Pos	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	c	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	fos	_	ADP	_	Number=Sing	_	_	_	_
35	induction	_	NOUN	_	Number=Sing	_	_	_	_
36	via	_	ADP	_	_	_	_	_	_
37	H2	_	NUM	_	Number=Sing	_	_	_	_
38	receptors	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	carried	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	out	_	ADP	_	_	_	_	_	_
6	using	_	VERB	_	VerbForm=Ger	_	_	_	_

1	H7	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	A	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	C	_	PROPN	_	Number=Sing	_	_	_	_
11	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	c	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	fos	_	ADP	_	Number=Sing	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	whereas	_	SCONJ	_	_	_	_	_	_
20	no	_	DET	_	_	_	_	_	_
21	effect	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	bisindolylmaleimide	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	specific	_	ADJ	_	Degree=Pos	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	C	_	PROPN	_	Number=Sing	_	_	_	_
32	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	modification	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	could	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	treatment	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	histamine	_	NOUN	_	Number=Sing	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	analogues	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Nevertheless	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	dibutyryl	_	ADJ	_	Degree=Pos	_	_	_	_
4	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
5	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	down	_	ADJ	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	regulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
15	proto	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	dibutyryl	_	ADJ	_	Degree=Pos	_	_	_	_
5	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
6	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	growth	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	dose	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	manner	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	whereas	_	SCONJ	_	_	_	_	_	_
17	histamine	_	NOUN	_	Number=Sing	_	_	_	_
18	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
21	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	U937	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Cells	_	NOUN	_	Number=Plur	_	_	_	_
2	pretreated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	dimaprit	_	NOUN	_	Number=Sing	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	decrease	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
14	addition	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	H2	_	NOUN	_	Number=Sing	_	_	_	_
17	agonists	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	whereas	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	prostaglandin	_	PROPN	_	Number=Sing	_	_	_	_
25	E2	_	PROPN	_	Number=Sing	_	_	_	_
26	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	unaltered	_	ADJ	_	Degree=Pos	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	H2	_	NOUN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	desensitization	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	time	_	NOUN	_	Number=Sing	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	histamine	_	NOUN	_	Number=Sing	_	_	_	_
6	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	several	_	ADJ	_	Degree=Pos	_	_	_	_
8	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
9	involved	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	such	_	ADJ	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	c	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	fos	_	ADP	_	Number=Sing	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	fails	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
29	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	U937	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	apparently	_	ADV	_	_	_	_	_	_
35	due	_	ADP	_	_	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
39	desensitization	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	H2	_	NUM	_	Number=Sing	_	_	_	_
42	receptors	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011047	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	highly	_	ADV	_	_	_	_	_	_
7	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	effector	_	NOUN	_	Number=Sing	_	_	_	_
10	CD4	_	PROPN	_	Number=Sing	_	_	_	_
11	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	helper	_	VERB	_	Number=Sing	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	Th2	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	Th1	_	DET	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
6	family	_	NOUN	_	Number=Sing	_	_	_	_
7	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	SCONJ	_	_	_	_	_	_
12	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	several	_	ADJ	_	Degree=Pos	_	_	_	_
17	cytokine	_	ADJ	_	Degree=Pos	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	during	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	immune	_	ADJ	_	Degree=Pos	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	such	_	ADJ	_	Degree=Pos	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	genes	_	NOUN	_	Number=Plur	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	4	_	NUM	_	NumType=Card	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	among	_	ADP	_	_	_	_	_	_
42	others	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	antigen	_	ADJ	_	Number=Sing	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	precursor	_	NOUN	_	Number=Sing	_	_	_	_
6	CD4	_	PROPN	_	Number=Sing	_	_	_	_
7	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	helper	_	VERB	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	pTh	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	proliferate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	differentiate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	into	_	ADP	_	_	_	_	_	_
11	two	_	NUM	_	NumType=Card	_	_	_	_
12	populations	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	effector	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	eTh1	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	eTh2	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	each	_	DET	_	_	_	_	_	_
23	one	_	NOUN	_	NumType=Card	_	_	_	_
24	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	pattern	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
30	that	_	PRON	_	PronType=Rel	_	_	_	_
31	distinguishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
33	from	_	ADP	_	_	_	_	_	_
34	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
35	precursors	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	eTh2	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	major	_	ADJ	_	Degree=Pos	_	_	_	_
6	source	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	while	_	SCONJ	_	_	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	interferon	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	eTh1	_	DET	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	reporter	_	NOUN	_	Number=Sing	_	_	_	_
6	transgenic	_	ADJ	_	Number=Sing	_	_	_	_
7	mice	_	NOUN	_	Number=Plur	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	show	_	VERB	_	VerbForm=Inf	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	activities	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	transiently	_	ADV	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	during	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	pTh	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	into	_	ADP	_	_	_	_	_	_
28	either	_	CCONJ	_	_	_	_	_	_
29	eTh1	_	NOUN	_	Number=Sing	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	eTh2	_	ADJ	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	IL	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	2	_	NUM	_	NumType=Card	_	_	_	_
41	as	_	ADP	_	_	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	common	_	ADJ	_	Degree=Pos	_	_	_	_
44	growth	_	NOUN	_	Number=Sing	_	_	_	_
45	factor	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	both	_	DET	_	_	_	_	_	_
48	pathways	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	although	_	SCONJ	_	_	_	_	_	_
4	NFAT	_	PROPN	_	Degree=Pos	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	similarly	_	ADV	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	eTh1	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	eTh2	_	DET	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	upon	_	ADP	_	_	_	_	_	_
17	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
18	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	only	_	ADV	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
23	complexes	_	NOUN	_	Number=Plur	_	_	_	_
24	present	_	VERB	_	Degree=Pos	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	eTh2	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	able	_	ADJ	_	Degree=Pos	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
32	high	_	ADJ	_	Degree=Pos	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	level	_	NOUN	_	Number=Sing	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	relatively	_	ADV	_	_	_	_	_	_
39	little	_	ADJ	_	Degree=Pos	_	_	_	_
40	NFAT	_	NOUN	_	Degree=Pos	_	_	_	_
41	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
42	activity	_	NOUN	_	Number=Sing	_	_	_	_
43	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
44	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	eTh1	_	DET	_	Number=Sing	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	activated	_	VERB	_	VerbForm=Inf	_	_	_	_
5	pTh	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	neither	_	CCONJ	_	_	_	_	_	_
9	eTh1	_	NOUN	_	Number=Sing	_	_	_	_
10	nor	_	CCONJ	_	_	_	_	_	_
11	eTh2	_	DET	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	significant	_	ADJ	_	Degree=Pos	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	upon	_	ADP	_	_	_	_	_	_
19	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	high	_	ADJ	_	Degree=Pos	_	_	_	_
24	levels	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
27	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
28	activities	_	NOUN	_	Number=Plur	_	_	_	_
29	directly	_	ADV	_	_	_	_	_	_
30	correlate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	4	_	NUM	_	NumType=Card	_	_	_	_
36	production	_	NOUN	_	Number=Sing	_	_	_	_
37	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	response	_	NOUN	_	Number=Sing	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	antigen	_	ADJ	_	VerbForm=Inf	_	_	_	_
42	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	eTh2	_	DET	_	Number=Sing	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	involved	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	effector	_	NOUN	_	Number=Sing	_	_	_	_
12	function	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	eTh2	_	DET	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	failure	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	eTh1	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	4	_	NUM	_	NumType=Card	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	response	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	antigen	_	NOUN	_	Number=Sing	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	due	_	ADJ	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	at	_	ADV	_	_	_	_	_	_
37	least	_	ADV	_	Degree=Sup	_	_	_	_
38	partially	_	ADV	_	_	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	failure	_	NOUN	_	Number=Sing	_	_	_	_
43	to	_	PART	_	_	_	_	_	_
44	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
45	high	_	ADJ	_	Degree=Pos	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	level	_	NOUN	_	Number=Sing	_	_	_	_
48	transcription	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	IL	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	4	_	NUM	_	NumType=Card	_	_	_	_
54	gene	_	NOUN	_	Number=Sing	_	_	_	_
55	by	_	ADP	_	_	_	_	_	_
56	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
4	could	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	therefore	_	ADV	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	critical	_	ADJ	_	Degree=Pos	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	polarization	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	eTh1	_	NOUN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	eTh2	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011049	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	C	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	calcineurin	_	NOUN	_	Degree=Pos	_	_	_	_
6	synergize	_	VERB	_	Number=Sing	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
10	kinase	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	key	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	regulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	immune	_	ADJ	_	Degree=Pos	_	_	_	_
25	response	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	TCR	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	cross	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	linking	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	part	_	NOUN	_	Number=Sing	_	_	_	_
13	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	degradation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	primary	_	ADJ	_	Degree=Pos	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	simultaneous	_	ADJ	_	Degree=Pos	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
19	messengers	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	TCR	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	signal	_	NOUN	_	Number=Sing	_	_	_	_
26	transduction	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	kinase	_	NOUN	_	Number=Sing	_	_	_	_
30	C	_	PROPN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	PKC	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	results	_	NOUN	_	Number=Plur	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
41	activation	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
45	kinase	_	NOUN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	IKK	_	PROPN	_	Number=Sing	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	complex	_	ADJ	_	Number=Sing	_	_	_	_
50	but	_	CCONJ	_	_	_	_	_	_
51	not	_	ADV	_	_	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	another	_	DET	_	_	_	_	_	_
54	putative	_	ADJ	_	Degree=Pos	_	_	_	_
55	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
56	kinase	_	NOUN	_	Number=Sing	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	p90	_	NOUN	_	Number=Sing	_	_	_	_
59	(	_	PUNCT	_	_	_	_	_	_
60	rsk	_	NOUN	_	Number=Sing	_	_	_	_
61	)	_	PUNCT	_	_	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IKK	_	PROPN	_	Number=Sing	_	_	_	_
7	complex	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	p90(rsk	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	vivo	_	PROPN	_	Degree=Pos	_	_	_	_
20	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
23	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	co-activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	PKC	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Each	_	DET	_	_	_	_	_	_
2	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	messenger	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	as	_	SCONJ	_	_	_	_	_	_
8	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	either	_	DET	_	_	_	_	_	_
11	one	_	NOUN	_	NumType=Card	_	_	_	_
12	reverses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	IKK	_	PROPN	_	Number=Sing	_	_	_	_
18	complex	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
21	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	vivo	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
4	negative	_	ADJ	_	Degree=Pos	_	_	_	_
5	forms	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IKKalpha	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	beta	_	NOUN	_	Number=Sing	_	_	_	_
11	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	only	_	ADV	_	_	_	_	_	_
14	IKKbeta	_	PROPN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	target	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	PKC	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	calcineurin	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	within	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	TCR	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	CD3	_	PROPN	_	Number=Sing	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	transduction	_	NOUN	_	Number=Sing	_	_	_	_
12	pathway	_	NOUN	_	Number=Sing	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	PKC	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	effective	_	ADJ	_	Degree=Pos	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	IKK	_	PROPN	_	Number=Sing	_	_	_	_
26	complex	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	T	_	PROPN	_	Number=Sing	_	_	_	_
33	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011050	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Attenuated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	function	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	variant	_	ADJ	_	Degree=Pos	_	_	_	_
6	form	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	helix	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	loop	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	helix	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	Id	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	3	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
24	splicing	_	NOUN	_	Number=Sing	_	_	_	_
25	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Id	_	NOUN	_	Number=Sing	_	_	_	_
3	family	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	helix	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	loop	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	helix	_	NOUN	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	function	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	negative	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulators	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	basic	_	ADJ	_	Degree=Pos	_	_	_	_
20	helix	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	loop	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	helix	_	NOUN	_	Number=Sing	_	_	_	_
25	proteins	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	regulation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	growth	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	identification	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	17	_	NUM	_	NumType=Card	_	_	_	_
10	kDa	_	NOUN	_	Number=Sing	_	_	_	_
11	variant	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	14	_	NUM	_	NumType=Card	_	_	_	_
15	kDa	_	NOUN	_	Number=Sing	_	_	_	_

1	Id	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	Id	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	3L	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	long	_	ADJ	_	Degree=Pos	_	_	_	_
11	version	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	possesses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	unique	_	ADJ	_	Degree=Pos	_	_	_	_
17	60	_	NUM	_	NumType=Card	_	_	_	_
18	amino	_	NOUN	_	Number=Sing	_	_	_	_
19	acid	_	NOUN	_	Number=Sing	_	_	_	_
20	carboxy	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	terminus	_	NOUN	_	Number=Sing	_	_	_	_
23	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	read	_	NOUN	_	Number=Sing	_	_	_	_
26	through	_	ADP	_	_	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	'	_	PUNCT	_	_	_	_	_	_
30	coding	_	NOUN	_	Number=Sing	_	_	_	_
31	intron	_	NOUN	_	Number=Sing	_	_	_	_
32	'	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
35	splicing	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	minor	_	ADJ	_	Degree=Pos	_	_	_	_
8	1.1	_	NUM	_	NumType=Card	_	_	_	_
9	kb	_	NOUN	_	Number=Sing	_	_	_	_
10	Id	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	3L	_	NUM	_	Number=Sing	_	_	_	_
13	transcript	_	NOUN	_	Number=Sing	_	_	_	_
14	together	_	ADV	_	_	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	predominant	_	ADJ	_	Degree=Pos	_	_	_	_
18	0.95	_	NUM	_	NumType=Card	_	_	_	_
19	kb	_	NOUN	_	Number=Sing	_	_	_	_
20	Id	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	3	_	NUM	_	NumType=Card	_	_	_	_
23	transcript	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	majority	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	adult	_	ADJ	_	Number=Sing	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	tissues	_	NOUN	_	Number=Plur	_	_	_	_
31	analysed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	variant	_	ADJ	_	Degree=Pos	_	_	_	_
3	Id	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	3L	_	NOUN	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	functionally	_	ADV	_	_	_	_	_	_
9	distinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	conventional	_	ADJ	_	Degree=Pos	_	_	_	_
12	Id	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	3	_	NUM	_	NumType=Card	_	_	_	_
15	since	_	SCONJ	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	vitro	_	ADJ	_	Number=Sing	_	_	_	_
19	DNA	_	PROPN	_	Number=Sing	_	_	_	_
20	mobility	_	NOUN	_	Number=Sing	_	_	_	_
21	shift	_	NOUN	_	Number=Sing	_	_	_	_
22	assays	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	greatly	_	ADV	_	_	_	_	_	_
27	impaired	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
30	ability	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	abrogate	_	VERB	_	VerbForm=Inf	_	_	_	_
33	binding	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	basic	_	ADJ	_	Degree=Pos	_	_	_	_
37	helix	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	loop	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	helix	_	NOUN	_	Number=Sing	_	_	_	_
42	protein	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	E47	_	NUM	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	to	_	ADP	_	_	_	_	_	_
47	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
48	E	_	NOUN	_	Number=Sing	_	_	_	_
49	box	_	NOUN	_	Number=Sing	_	_	_	_
50	recognition	_	NOUN	_	Number=Sing	_	_	_	_
51	sequence	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011051	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Lipopolysaccharide	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	potent	_	ADJ	_	Degree=Pos	_	_	_	_
5	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	stimulator	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	type	_	NOUN	_	Number=Sing	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Lipopolysaccharide	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	LPS	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	potently	_	ADV	_	_	_	_	_	_
6	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
9	virus	_	NOUN	_	Number=Sing	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	long	_	ADJ	_	Degree=Pos	_	_	_	_
14	terminal	_	NOUN	_	Number=Sing	_	_	_	_
15	repeat	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	LTR	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	CAT	_	NOUN	_	Number=Sing	_	_	_	_
24	constructs	_	NOUN	_	Number=Plur	_	_	_	_
25	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	into	_	ADP	_	_	_	_	_	_
27	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	like	_	ADP	_	Degree=Pos	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	lines	_	NOUN	_	Number=Plur	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	not	_	ADV	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	T	_	NOUN	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	line	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	through	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	LPS	_	NOUN	_	Number=Sing	_	_	_	_
8	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	DNA	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	indistinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	PROPN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	U937	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	THP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	dramatically	_	ADV	_	_	_	_	_	_
7	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	chronically	_	ADV	_	_	_	_	_	_
15	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	like	_	ADP	_	_	_	_	_	_
21	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	U1	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	produces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	very	_	ADV	_	_	_	_	_	_
30	low	_	ADJ	_	Degree=Pos	_	_	_	_
31	levels	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	HIV	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	at	_	ADP	_	_	_	_	_	_
37	baseline	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	viral	_	ADJ	_	Degree=Pos	_	_	_	_
5	production	_	NOUN	_	Number=Sing	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	line	_	NOUN	_	Number=Sing	_	_	_	_
10	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	only	_	ADV	_	_	_	_	_	_
12	if	_	SCONJ	_	_	_	_	_	_
13	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
21	colony	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	GM	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	CSF	_	PROPN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	before	_	ADP	_	_	_	_	_	_
31	treatment	_	NOUN	_	Number=Sing	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	LPS	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	production	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	increase	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	RNA	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	PROPN	_	Number=Sing	_	_	_	_
28	B.	_	PROPN	_	Number=Sing	_	_	_	_
29	LPS	_	PROPN	_	Number=Sing	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	not	_	ADV	_	_	_	_	_	_
32	able	_	ADJ	_	Degree=Pos	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
35	HIV	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	production	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	cloned	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
42	T	_	NOUN	_	Number=Sing	_	_	_	_
43	cell	_	NOUN	_	Number=Sing	_	_	_	_
44	line	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	LPS	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	replication	_	NOUN	_	Number=Sing	_	_	_	_
10	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	picogram	_	NOUN	_	Number=Sing	_	_	_	_
13	per	_	ADP	_	_	_	_	_	_
14	milliliter	_	NOUN	_	Number=Sing	_	_	_	_
15	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	clinically	_	ADV	_	_	_	_	_	_
20	significant	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	SCONJ	_	_	_	_	_	_
22	understanding	_	VERB	_	VerbForm=Ger	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	variability	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	natural	_	ADJ	_	Degree=Pos	_	_	_	_
28	history	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	HIV	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	infection	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011054	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	disruption	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	MyD88	_	PROPN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	results	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	loss	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	18	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	mediated	_	VERB	_	Degree=Pos	_	_	_	_
21	function	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	MyD88	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	originally	_	ADV	_	_	_	_	_	_
4	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
8	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	act	_	VERB	_	VerbForm=Inf	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	adaptor	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
30	by	_	SCONJ	_	_	_	_	_	_
31	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	both	_	CCONJ	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	receptor	_	NOUN	_	Number=Sing	_	_	_	_
39	complex	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	1	_	NUM	_	NumType=Card	_	_	_	_
44	receptor	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	kinase	_	PROPN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	IRAK	_	PROPN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Mice	_	NOUN	_	Number=Plur	_	_	_	_
2	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	targeting	_	VERB	_	VerbForm=Ger	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	lack	_	VERB	_	VerbForm=Inf	_	_	_	_
8	MyD88	_	PROPN	_	Number=Sing	_	_	_	_
9	have	_	VERB	_	VerbForm=Inf	_	_	_	_
10	defects	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
15	as	_	ADV	_	_	_	_	_	_
16	well	_	ADV	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	acute	_	ADJ	_	Degree=Pos	_	_	_	_
21	phase	_	NOUN	_	Number=Sing	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	response	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	interferon	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	gamma	_	NOUN	_	Number=Sing	_	_	_	_
6	production	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	natural	_	ADJ	_	Degree=Pos	_	_	_	_
9	killer	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	18	_	NUM	_	NumType=Card	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	abrogated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	NOUN	_	Number=Sing	_	_	_	_
3	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	response	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	18	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
15	N	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	terminal	_	NOUN	_	Number=Sing	_	_	_	_
18	kinase	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	JNK	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	MyD88-/-	_	NUM	_	NumType=Card	_	_	_	_
26	Th1	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	developing	_	VERB	_	VerbForm=Ger	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	MyD88	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	critical	_	ADJ	_	Degree=Pos	_	_	_	_
12	component	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	signaling	_	NOUN	_	Number=Sing	_	_	_	_
16	cascade	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	as	_	ADV	_	_	_	_	_	_
26	well	_	ADV	_	Degree=Pos	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	18	_	NUM	_	NumType=Card	_	_	_	_
31	receptor	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011061	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid-	_	PUNCT	_	_	_	_	_	_
2	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
10	6TG1.1	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
13	ICR27TK.3	_	NUM	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Following	_	VERB	_	VerbForm=Ger	_	_	_	_
2	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
3	treatment	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	6TG1.1	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	chromatin	_	NOUN	_	Degree=Pos	_	_	_	_
9	fragmentation	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	delay	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	24	_	NUM	_	NumType=Card	_	_	_	_
17	h	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Fragmentation	_	NOUN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	ICR27TK.3	_	NUM	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
10	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
11	receptors	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	L753F	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	retain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	ability	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	repress	_	VERB	_	VerbForm=Inf	_	_	_	_
26	AP	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Nor	_	CCONJ	_	_	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	fragmentation	_	NOUN	_	Number=Sing	_	_	_	_
4	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	after	_	ADP	_	_	_	_	_	_
6	treatment	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	RU38486	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	repression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	involved	_	ADJ	_	Degree=Pos	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	other	_	ADJ	_	Degree=Pos	_	_	_	_
5	systems	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	fragmentation	_	NOUN	_	Number=Sing	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	ongoing	_	ADJ	_	Degree=Pos	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
9	anytime	_	NOUN	_	Number=Sing	_	_	_	_
10	during	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
13	18	_	NUM	_	NumType=Card	_	_	_	_
14	h	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
17	treatment	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	as	_	ADV	_	_	_	_	_	_
20	effective	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
23	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
24	fragmentation	_	NOUN	_	Number=Sing	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	entire	_	ADJ	_	Degree=Pos	_	_	_	_
30	period	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
33	that	_	SCONJ	_	_	_	_	_	_
34	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	component	_	NOUN	_	Number=Sing	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
41	turnover	_	NOUN	_	Number=Sing	_	_	_	_
42	rate	_	NOUN	_	Number=Sing	_	_	_	_
43	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
44	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Dexamethasone	_	PROPN	_	Number=Sing	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	completely	_	ADV	_	_	_	_	_	_
4	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
6	13	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	acetate	_	ADJ	_	Degree=Pos	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	elicited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	increase	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	amount	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	immunoreactive	_	ADJ	_	Degree=Pos	_	_	_	_
30	IkappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
34	6TG1	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	but	_	CCONJ	_	_	_	_	_	_
39	not	_	PART	_	_	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
42	ICR27TK.3	_	NOUN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	mild	_	ADJ	_	Degree=Pos	_	_	_	_
5	detergent	_	NOUN	_	Degree=Pos	_	_	_	_
6	treatment	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	extracts	_	NOUN	_	Number=Plur	_	_	_	_
10	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
14	amount	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	complexed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	some	_	DET	_	_	_	_	_	_
27	other	_	ADJ	_	Degree=Pos	_	_	_	_
28	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	labile	_	ADJ	_	Degree=Pos	_	_	_	_
9	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	such	_	ADJ	_	Degree=Pos	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011065	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	casein	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	cross	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	talk	_	NOUN	_	Number=Sing	_	_	_	_
15	between	_	ADP	_	_	_	_	_	_
16	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	signaling	_	VERB	_	Number=Sing	_	_	_	_
20	molecules	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	beta	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	casein	_	NOUN	_	Number=Sing	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	widely	_	ADV	_	_	_	_	_	_
9	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	monitor	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	STAT	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	signal	_	NOUN	_	Number=Sing	_	_	_	_
18	transducer	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	activator	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	5	_	NUM	_	NumType=Card	_	_	_	_
25	since	_	SCONJ	_	_	_	_	_	_
26	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	originally	_	ADV	_	_	_	_	_	_
29	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	mediator	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	PRL	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
37	beta-casein	_	NOUN	_	Number=Sing	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	not	_	ADV	_	_	_	_	_	_
4	only	_	ADV	_	_	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	beta	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	casein	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	other	_	ADJ	_	Degree=Pos	_	_	_	_
23	molecules	_	NOUN	_	Number=Plur	_	_	_	_
24	such	_	ADJ	_	Degree=Pos	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	Ras	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	regulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	beta	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	casein	_	NOUN	_	Tense=Past|VerbForm=Part	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	casein	_	NOUN	_	Degree=Pos	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	line	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	CTLL	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	response	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	which	_	PRON	_	PronType=Rel	_	_	_	_
36	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	4	_	NUM	_	NumType=Card	_	_	_	_
5	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
11	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	STAT5	_	NOUN	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	regulated	_	VERB	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	CTLL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	i.e.	_	X	_	_	_	_	_	_
24	beta-casein	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
30	SH2	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
33	protein	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	CIS	_	PROPN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	oncostatin	_	NOUN	_	_	_	_	_	_
40	M	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	OSM	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
46	that	_	SCONJ	_	_	_	_	_	_
47	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
48	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	by	_	ADP	_	_	_	_	_	_
50	IL	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	4	_	NUM	_	NumType=Card	_	_	_	_
53	substitutes	_	NOUN	_	Number=Plur	_	_	_	_
54	for	_	ADP	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	function	_	NOUN	_	Number=Sing	_	_	_	_
57	of	_	ADP	_	_	_	_	_	_
58	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
59	in	_	ADP	_	_	_	_	_	_
60	T	_	PROPN	_	Number=Sing	_	_	_	_
61	cells	_	NOUN	_	Number=Plur	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	beta-casein	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
15	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
16	effect	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	Dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
19	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	sequence	_	NOUN	_	Number=Sing	_	_	_	_
22	between	_	ADP	_	_	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	155	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	-	_	SYM	_	_	_	_	_	_
27	193	_	NUM	_	NumType=Card	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	beta	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	casein	_	NOUN	_	Number=Sing	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Coincidentally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	deletion	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	beta-casein	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	active	_	ADJ	_	Degree=Pos	_	_	_	_
5	form	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Ras	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	Ras	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	G12V	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	beta-casein	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	OSM	_	PROPN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	negative	_	ADJ	_	Degree=Pos	_	_	_	_
30	effect	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	Ras	_	PROPN	_	Number=Sing	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	region	_	NOUN	_	Number=Sing	_	_	_	_
38	between	_	ADP	_	_	_	_	_	_
39	-	_	SYM	_	_	_	_	_	_
40	105	_	NUM	_	NumType=Card	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	-	_	SYM	_	_	_	_	_	_
43	193	_	NUM	_	NumType=Card	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	beta	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	casein	_	NOUN	_	Number=Sing	_	_	_	_
49	promoter	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
3	contradiction	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
9	negative	_	ADJ	_	Degree=Pos	_	_	_	_
10	form	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Ras	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	RasN17	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	also	_	ADV	_	_	_	_	_	_
17	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
30	beta-casein	_	NOUN	_	Number=Sing	_	_	_	_
31	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
32	element	_	NOUN	_	Number=Sing	_	_	_	_
33	as	_	ADV	_	_	_	_	_	_
34	well	_	ADV	_	Degree=Pos	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	promoters	_	NOUN	_	Number=Plur	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	CIS	_	PROPN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	OSM	_	PROPN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	Ras	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	G12V	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	complemented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	signaling	_	VERB	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	erythropoietin	_	NOUN	_	Degree=Pos	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	mutant	_	NOUN	_	Number=Sing	_	_	_	_
15	defective	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	Ras	_	PROPN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	augmented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	beta	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	casein	_	NOUN	_	Number=Sing	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	mutant	_	NOUN	_	Number=Sing	_	_	_	_
32	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
33	receptor	_	NOUN	_	Number=Sing	_	_	_	_
34	signaling	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	possible	_	ADJ	_	Degree=Pos	_	_	_	_
39	role	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	Ras	_	PROPN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	mediated	_	VERB	_	Degree=Pos	_	_	_	_
46	gene	_	NOUN	_	Number=Sing	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	collectively	_	ADV	_	_	_	_	_	_
4	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	complex	_	ADJ	_	Degree=Pos	_	_	_	_
7	interaction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	other	_	ADJ	_	Degree=Pos	_	_	_	_
12	signaling	_	NOUN	_	Number=Sing	_	_	_	_
13	pathways	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	illustrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	integration	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	opposing	_	VERB	_	Degree=Pos	_	_	_	_
25	signals	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011067	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	like	_	ADP	_	Degree=Pos	_	_	_	_
13	drugs	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Aspirin	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	like	_	ADP	_	Degree=Pos	_	_	_	_
4	drugs	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	ALD	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
9	calcium	_	NOUN	_	Number=Sing	_	_	_	_
10	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	essential	_	ADJ	_	Degree=Pos	_	_	_	_
14	component	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	biosynthesis	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	extent	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Int	_	_	_	_
7	ALD	_	PROPN	_	Number=Sing	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	mimic	_	VERB	_	VerbForm=Inf	_	_	_	_
10	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
11	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	signaling	_	NOUN	_	Number=Sing	_	_	_	_
19	steps	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	ALD	_	ADJ	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	ALD	_	PROPN	_	_	_	_	_	_
5	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	transient	_	ADJ	_	Degree=Pos	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	PKC	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	no	_	DET	_	_	_	_	_	_
18	effect	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	comparison	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	anti-CD3	_	ADJ	_	Number=Sing	_	_	_	_
24	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
29	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
30	nor	_	CCONJ	_	_	_	_	_	_
31	on	_	ADP	_	_	_	_	_	_
32	PCL	_	NOUN	_	Number=Sing	_	_	_	_
33	gamma	_	NOUN	_	Number=Sing	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
36	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	ALD	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	calcium	_	NOUN	_	Number=Sing	_	_	_	_
5	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	PKC	_	PROPN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	independent	_	ADJ	_	Degree=Pos	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	tyrosine	_	ADJ	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	kinase	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	as	_	SCONJ	_	_	_	_	_	_
17	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	lack	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	effect	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	herbimycin	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	specific	_	ADJ	_	Degree=Pos	_	_	_	_
33	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	detected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	no	_	DET	_	_	_	_	_	_
5	IL	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	ALD	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	capable	_	ADJ	_	Degree=Pos	_	_	_	_
23	of	_	SCONJ	_	_	_	_	_	_
24	binding	_	VERB	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	three	_	NUM	_	NumType=Card	_	_	_	_
27	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	sequences	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	region	_	NOUN	_	Number=Sing	_	_	_	_
36	:	_	PUNCT	_	_	_	_	_	_
37	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	kappa	_	NOUN	_	Number=Sing	_	_	_	_
41	B	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	AP	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	activities	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	only	_	ADV	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	depended	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	calcium	_	NOUN	_	Number=Sing	_	_	_	_
10	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	PKC	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	ALD	_	PROPN	_	_	_	_	_	_
6	cause	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	transient	_	ADJ	_	Degree=Pos	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	significant	_	ADJ	_	Degree=Pos	_	_	_	_
10	changes	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	transmembrane	_	NOUN	_	Number=Sing	_	_	_	_
15	signaling	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	although	_	SCONJ	_	_	_	_	_	_
18	some	_	DET	_	_	_	_	_	_
19	events	_	NOUN	_	Number=Plur	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	anti-CD3	_	ADJ	_	Degree=Pos	_	_	_	_
25	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
26	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	ALD	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	signal	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	transmitted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	DNA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	several	_	ADJ	_	Degree=Pos	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	ALD	_	PROPN	_	Number=Sing	_	_	_	_
5	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	capable	_	ADJ	_	Degree=Pos	_	_	_	_
9	of	_	SCONJ	_	_	_	_	_	_
10	causing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	complete	_	ADJ	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011069	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Comparison	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
5	domains	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	mammary	_	ADJ	_	Degree=Pos	_	_	_	_
15	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Stat	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	signal	_	NOUN	_	Number=Sing	_	_	_	_
4	transducers	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	activators	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	Jak	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	Janus	_	PROPN	_	Number=Sing	_	_	_	_
14	kinases	_	NOUN	_	Number=Plur	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	central	_	ADJ	_	Degree=Pos	_	_	_	_
19	components	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	signal	_	ADJ	_	Number=Sing	_	_	_	_
23	transduction	_	NOUN	_	Number=Sing	_	_	_	_
24	events	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	rapidly	_	ADV	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	various	_	ADJ	_	Degree=Pos	_	_	_	_
7	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	hormones	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	ligand	_	NOUN	_	Number=Sing	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	dimerization	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	Stat	_	PROPN	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
15	residues	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	Jak	_	PROPN	_	Number=Sing	_	_	_	_
18	kinases	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	Stat	_	PROPN	_	Number=Sing	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	form	_	NOUN	_	Number=Sing	_	_	_	_
5	homo	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	translocate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	induce	_	VERB	_	Degree=Pos	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	active	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	mammary	_	ADJ	_	Degree=Pos	_	_	_	_
10	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	immune	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Prolactin	_	NOUN	_	Number=Sing	_	_	_	_
2	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	able	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	survival	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
5	potential	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4-	_	NUM	_	NumType=Card	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	HC11	_	PROPN	_	Number=Sing	_	_	_	_
13	mammary	_	ADJ	_	Number=Sing	_	_	_	_
14	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	casein	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	COS7	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	able	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	further	_	ADV	_	VerbForm=Inf	_	_	_	_
8	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	action	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	carboxyl	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	terminal	_	ADJ	_	Number=Sing	_	_	_	_
8	region	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	recombination	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
19	DNA	_	PROPN	_	Number=Sing	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	domain	_	NOUN	_	Number=Sing	_	_	_	_
22	allowed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	delimitation	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	characterization	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
30	domain	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	potencies	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
6	domains	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	viral	_	ADJ	_	Degree=Pos	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	VP16	_	NOUN	_	Number=Sing	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
2	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
5	domain	_	NOUN	_	Number=Sing	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	about	_	ADV	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	fold	_	NOUN	_	VerbForm=Inf	_	_	_	_
12	stronger	_	ADJ	_	Degree=Cmp	_	_	_	_
13	than	_	ADP	_	_	_	_	_	_
14	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	Ba	_	PROPN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	F3	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
12	domain	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	4	_	NUM	_	NumType=Card	_	_	_	_
19	regulated	_	VERB	_	Degree=Pos	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	independently	_	ADV	_	_	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	DNA	_	NOUN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	function	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011070	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	activator	_	NOUN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	AP	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	CD28	_	PROPN	_	Number=Sing	_	_	_	_
17	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	phosphatidylinositol	_	NOUN	_	Number=Sing	_	_	_	_
21	3	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	acidic	_	ADJ	_	Degree=Pos	_	_	_	_
26	sphingomyelinase	_	NOUN	_	Number=Sing	_	_	_	_
27	signals	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	major	_	ADJ	_	Degree=Pos	_	_	_	_
3	obstacle	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	SCONJ	_	_	_	_	_	_
5	understanding	_	VERB	_	VerbForm=Ger	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	signaling	_	NOUN	_	Number=Sing	_	_	_	_
8	events	_	NOUN	_	Number=Plur	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	follow	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	CD28	_	PROPN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	ligation	_	NOUN	_	Number=Sing	_	_	_	_
14	arises	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	fact	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	CD28	_	PROPN	_	Number=Sing	_	_	_	_
20	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	costimulus	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	TCR	_	NOUN	_	Number=Sing	_	_	_	_
26	engagement	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	making	_	VERB	_	VerbForm=Ger	_	_	_	_
29	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
30	difficult	_	ADJ	_	Degree=Pos	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	assess	_	VERB	_	VerbForm=Inf	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	relative	_	ADJ	_	Degree=Pos	_	_	_	_
35	contribution	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	CD28	_	NOUN	_	Number=Sing	_	_	_	_
38	signals	_	NOUN	_	Number=Plur	_	_	_	_
39	as	_	ADP	_	_	_	_	_	_
40	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
41	from	_	ADP	_	_	_	_	_	_
42	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	TCR	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	overcome	_	VERB	_	VerbForm=Inf	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	problem	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	exploited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	observation	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	blasts	_	NOUN	_	Number=Plur	_	_	_	_
17	can	_	AUX	_	VerbForm=Fin	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	via	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	CD28	_	NOUN	_	Number=Sing	_	_	_	_
23	surface	_	NOUN	_	Number=Sing	_	_	_	_
24	molecule	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	absence	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	antigenic	_	ADJ	_	Degree=Pos	_	_	_	_
30	challenge	_	NOUN	_	Number=Sing	_	_	_	_
31	;	_	PUNCT	_	_	_	_	_	_
32	thus	_	ADV	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
35	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
37	able	_	ADJ	_	Degree=Pos	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	observe	_	VERB	_	VerbForm=Inf	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	response	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	normal	_	ADJ	_	Degree=Pos	_	_	_	_
44	T	_	NOUN	_	Number=Sing	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	to	_	ADP	_	_	_	_	_	_
47	CD28	_	PROPN	_	Number=Sing	_	_	_	_
48	activation	_	NOUN	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	isolation	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	system	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	CD28	_	PROPN	_	Number=Sing	_	_	_	_
9	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	B7	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	CHO	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	measurable	_	ADJ	_	Degree=Pos	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	production	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	generation	_	NOUN	_	Number=Sing	_	_	_	_
9	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	B7	_	PROPN	_	Number=Sing	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	activator	_	NOUN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	complexes	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	but	_	CCONJ	_	_	_	_	_	_
37	not	_	ADV	_	_	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	AT	_	NOUN	_	_	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	engagement	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	TCR	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	class	_	NOUN	_	Number=Sing	_	_	_	_
10	II	_	NUM	_	NumType=Card	_	_	_	_
11	MHC	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	superantigen	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	either	_	CCONJ	_	_	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	without	_	ADP	_	_	_	_	_	_
19	CD28	_	PROPN	_	Number=Sing	_	_	_	_
20	ligation	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	induction	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	AT	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	AP	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
39	as	_	ADV	_	_	_	_	_	_
40	well	_	ADV	_	Degree=Pos	_	_	_	_
41	as	_	ADP	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	2	_	NUM	_	NumType=Card	_	_	_	_
45	production	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	selective	_	ADJ	_	Degree=Pos	_	_	_	_
3	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	signaling	_	NOUN	_	Number=Sing	_	_	_	_
9	pathways	_	NOUN	_	Number=Plur	_	_	_	_
10	involved	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	CD28	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	generation	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	chloroquine	_	VERB	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	acidic	_	ADJ	_	Degree=Pos	_	_	_	_
17	sphingomyelinase	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	not	_	ADV	_	_	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	phosphatidylinositol	_	NOUN	_	Number=Sing	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kinase	_	NOUN	_	Number=Sing	_	_	_	_
27	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	wortmannin	_	ADJ	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	generation	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	wortmannin	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	variably	_	ADV	_	_	_	_	_	_
16	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	chloroquine	_	VERB	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	normal	_	ADJ	_	Degree=Pos	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	CD28	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	signals	_	NOUN	_	Number=Plur	_	_	_	_
15	can	_	AUX	_	VerbForm=Fin	_	_	_	_
16	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
18	at	_	ADV	_	_	_	_	_	_
19	least	_	ADV	_	Degree=Sup	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	part	_	NOUN	_	Number=Sing	_	_	_	_
22	via	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	AP	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	generation	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	that	_	SCONJ	_	_	_	_	_	_
34	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
35	response	_	NOUN	_	Number=Sing	_	_	_	_
36	uses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	both	_	CCONJ	_	_	_	_	_	_
38	acidic	_	ADJ	_	Degree=Pos	_	_	_	_
39	sphingomyelinase	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	phosphatidylinositol	_	PROPN	_	Number=Sing	_	_	_	_
42	3	_	NUM	_	NumType=Card	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	kinase	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	pathways	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011072	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Different	_	ADJ	_	Degree=Pos	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	requirements	_	NOUN	_	Number=Plur	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	upstream	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	GATA	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	lineage	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	GATA	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	localized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	317	_	NUM	_	NumType=Card	_	_	_	_
6	base	_	NOUN	_	Number=Sing	_	_	_	_
7	pair	_	NOUN	_	Number=Sing	_	_	_	_
8	cis	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	HS	_	PROPN	_	Number=Sing	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	DNase	_	NOUN	_	Number=Sing	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	hypersensitive	_	VERB	_	Degree=Pos	_	_	_	_
26	site	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	lies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	approx	_	ADV	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	3.7	_	NUM	_	NumType=Card	_	_	_	_
2	kilobases	_	NOUN	_	Number=Plur	_	_	_	_
3	upstream	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	murine	_	NOUN	_	Number=Sing	_	_	_	_
7	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	GATA	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	IE	_	X	_	_	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	HS	_	PROPN	_	Number=Sing	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	directs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	high	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	level	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	reporter	_	NOUN	_	Number=Sing	_	_	_	_
10	GATA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1/lacZ	_	ADJ	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	primitive	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	definitive	_	ADJ	_	Degree=Pos	_	_	_	_
18	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	megakaryocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
24	mice	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Comparative	_	ADJ	_	Degree=Pos	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	HS	_	PROPN	_	Number=Sing	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	mouse	_	NOUN	_	Number=Sing	_	_	_	_
11	shows	_	NOUN	_	Number=Plur	_	_	_	_
12	approx	_	ADV	_	_	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	63	_	NUM	_	NumType=Card	_	_	_	_
2	%	_	SYM	_	Number=Sing	_	_	_	_
3	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
4	identity	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	more	_	ADV	_	_	_	_	_	_
8	conserved	_	ADJ	_	Degree=Pos	_	_	_	_
9	core	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	169	_	NUM	_	NumType=Card	_	_	_	_
12	base	_	NOUN	_	Number=Sing	_	_	_	_
13	pairs	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	86	_	NUM	_	NumType=Card	_	_	_	_
16	%	_	SYM	_	Number=Sing	_	_	_	_
17	identity	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	core	_	NOUN	_	Number=Sing	_	_	_	_
3	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	GATA	_	NOUN	_	Number=Sing	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	separated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	base	_	NOUN	_	Number=Sing	_	_	_	_
11	pairs	_	NOUN	_	Number=Plur	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	E	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	box	_	NOUN	_	Number=Sing	_	_	_	_
17	motif	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	composite	_	ADJ	_	Degree=Pos	_	_	_	_
3	motif	_	NOUN	_	Number=Sing	_	_	_	_
4	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	multi-protein	_	ADJ	_	Degree=Pos	_	_	_	_
7	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	complex	_	NOUN	_	Number=Sing	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	GATA	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	SCL	_	PROPN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	tal	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	E2A	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	Lmo2	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	Ldb	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Point	_	NOUN	_	Number=Sing	_	_	_	_
2	mutations	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	GATA	_	PROPN	_	Number=Sing	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	abolishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	HS	_	PROPN	_	Number=Sing	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	function	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	whereas	_	SCONJ	_	_	_	_	_	_
13	mutation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	E	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	box	_	NOUN	_	Number=Sing	_	_	_	_
19	motif	_	NOUN	_	Number=Sing	_	_	_	_
20	still	_	ADV	_	_	_	_	_	_
21	allows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	reporter	_	NOUN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	both	_	DET	_	_	_	_	_	_
27	lineages	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Strict	_	ADJ	_	Degree=Pos	_	_	_	_
2	dependence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HS	_	NOUN	_	Number=Sing	_	_	_	_
5	I	_	NOUN	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	GATA	_	PROPN	_	Number=Sing	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	implies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	assembly	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	complex	_	NOUN	_	Number=Sing	_	_	_	_
18	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	GATA	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	presumably	_	ADV	_	_	_	_	_	_
25	GATA	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	GATA	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	critical	_	ADJ	_	Degree=Pos	_	_	_	_
35	to	_	SCONJ	_	_	_	_	_	_
36	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	maintaining	_	VERB	_	VerbForm=Ger	_	_	_	_
39	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
40	function	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	dissection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	317	_	NUM	_	NumType=Card	_	_	_	_
6	base	_	NOUN	_	Number=Sing	_	_	_	_
7	pair	_	NOUN	_	Number=Sing	_	_	_	_
8	region	_	NOUN	_	Number=Sing	_	_	_	_
9	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	whereas	_	SCONJ	_	_	_	_	_	_
13	all	_	DET	_	_	_	_	_	_
14	317	_	NUM	_	NumType=Card	_	_	_	_
15	base	_	NOUN	_	Number=Sing	_	_	_	_
16	pairs	_	NOUN	_	Number=Plur	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	megakaryocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	only	_	ADV	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	5	_	NUM	_	NumType=Card	_	_	_	_
27	'	_	NOUN	_	_	_	_	_	_
28	62	_	NUM	_	NumType=Card	_	_	_	_
29	base	_	NOUN	_	Number=Sing	_	_	_	_
30	pairs	_	NOUN	_	Number=Plur	_	_	_	_
31	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	needed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	for	_	ADP	_	_	_	_	_	_
34	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	specific	_	ADJ	_	Degree=Pos	_	_	_	_
37	reporter	_	NOUN	_	Number=Sing	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	differential	_	ADJ	_	Degree=Pos	_	_	_	_
5	lineage	_	NOUN	_	Number=Sing	_	_	_	_
6	requirements	_	NOUN	_	Number=Plur	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	within	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	HS	_	PROPN	_	Number=Sing	_	_	_	_
12	I	_	NOUN	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	element	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011074	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Rescue	_	VERB	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	death	_	NOUN	_	Number=Sing	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	deprivation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	antigen	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	clones	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	control	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	survival	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	death	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	central	_	ADJ	_	Degree=Pos	_	_	_	_
12	importance	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	tissues	_	NOUN	_	Number=Plur	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	high	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	turnover	_	NOUN	_	Number=Sing	_	_	_	_
19	such	_	ADJ	_	Degree=Pos	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
23	system	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	deprivation	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	antigen	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	helper	_	NOUN	_	Number=Sing	_	_	_	_
23	clones	_	NOUN	_	Number=Plur	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	different	_	ADJ	_	Degree=Pos	_	_	_	_
26	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
27	production	_	NOUN	_	Number=Sing	_	_	_	_
28	profiles	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	interferon	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IFN	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	IFN	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	beta	_	NOUN	_	Number=Sing	_	_	_	_
21	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	deprivation	_	NOUN	_	Number=Sing	_	_	_	_
26	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	Th0	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	Th1	_	PROPN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	clones	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	protects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	clones	_	NOUN	_	Number=Plur	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	deprivation	_	NOUN	_	Number=Sing	_	_	_	_
17	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
18	accompanying	_	VERB	_	VerbForm=Ger	_	_	_	_
19	active	_	ADJ	_	Degree=Pos	_	_	_	_
20	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	P53	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	Rb	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	xL	_	PROPN	_	Number=Sing	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	IFN	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	beta	_	NOUN	_	Number=Sing	_	_	_	_
9	rescued	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	clones	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
15	without	_	ADP	_	_	_	_	_	_
16	active	_	ADJ	_	Degree=Pos	_	_	_	_
17	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	proteins	_	NOUN	_	Number=Plur	_	_	_	_
26	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	so	_	ADV	_	_	_	_	_	_
28	far	_	ADV	_	Degree=Pos	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	be	_	AUX	_	VerbForm=Inf	_	_	_	_
4	due	_	ADP	_	_	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	fact	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
18	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	S	_	PROPN	_	_	_	_	_	_
21	+	_	SYM	_	_	_	_	_	_

1	G2	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	M	_	NUM	_	Number=Sing	_	_	_	_
4	phases	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	cycle	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	whereas	_	SCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	vast	_	ADJ	_	Degree=Pos	_	_	_	_
13	majority	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	IFN	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	beta	_	NOUN	_	Number=Sing	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	G0	_	NUM	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	G1	_	NOUN	_	Number=Sing	_	_	_	_
30	phase	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	IFN	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	/	_	PUNCT	_	_	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	specifically	_	ADV	_	_	_	_	_	_
7	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
9	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	translocation	_	NOUN	_	Number=Sing	_	_	_	_
12	into	_	ADP	_	_	_	_	_	_
13	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	signal	_	NOUN	_	Number=Sing	_	_	_	_
16	transducers	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	activators	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	STAT	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	clones	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	over-expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	STAT2	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	transfection	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
12	prevented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	clones	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	mediate	_	VERB	_	Degree=Pos	_	_	_	_
13	anti-apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
14	effect	_	NOUN	_	Number=Sing	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	other	_	ADJ	_	Degree=Pos	_	_	_	_
17	pathways	_	NOUN	_	Number=Plur	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	growth	_	NOUN	_	Number=Sing	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	deprivation	_	NOUN	_	Number=Sing	_	_	_	_
28	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011081	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Anti-rheumatic	_	ADJ	_	Degree=Pos	_	_	_	_
2	compound	_	NOUN	_	Number=Sing	_	_	_	_
3	aurothioglucose	_	NOUN	_	Number=Sing	_	_	_	_
4	inhibits	_	VERB	_	Number=Plur	_	_	_	_
5	tumor	_	NOUN	_	Number=Sing	_	_	_	_
6	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	replication	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	latently	_	ADV	_	_	_	_	_	_
18	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	OM10.1	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	Ach2	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	potent	_	ADJ	_	Degree=Pos	_	_	_	_
7	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	activator	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Down	_	ADV	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	regulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	replication	_	NOUN	_	Number=Sing	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	latently	_	ADV	_	_	_	_	_	_
18	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Gold	_	NOUN	_	Degree=Pos	_	_	_	_
2	compounds	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	effectively	_	ADV	_	_	_	_	_	_
6	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	many	_	ADJ	_	Degree=Pos	_	_	_	_
9	decades	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	treatment	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	rheumatoid	_	NOUN	_	Number=Sing	_	_	_	_
15	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	gold	_	ADJ	_	Degree=Pos	_	_	_	_
6	compounds	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	especially	_	ADV	_	_	_	_	_	_
9	aurothioglucose	_	ADJ	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	AuTG	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	monovalent	_	ADJ	_	Degree=Pos	_	_	_	_
15	gold	_	ADJ	_	Degree=Pos	_	_	_	_
16	ion	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	DNA	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	vitro	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	efficacy	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	gold	_	ADJ	_	Degree=Pos	_	_	_	_
12	compound	_	NOUN	_	Number=Sing	_	_	_	_
13	AuTG	_	PROPN	_	Number=Sing	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	replication	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	latently	_	ADV	_	_	_	_	_	_
22	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	OM10.1	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	Ach2	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	TNF	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha-induced	_	VERB	_	Number=Sing	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	replication	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	OM10.1	_	NUM	_	NumType=Card	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	Ach2	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	significantly	_	ADV	_	_	_	_	_	_
12	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	non-cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
15	doses	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	AuTG	_	PROPN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	>	_	PUNCT	_	_	_	_	_	_
20	10	_	NUM	_	NumType=Card	_	_	_	_
21	microM	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	OM10.1	_	NUM	_	NumType=Card	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	>	_	PUNCT	_	_	_	_	_	_
27	25	_	NUM	_	NumType=Card	_	_	_	_
28	F.M	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	Ach2	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	while	_	SCONJ	_	_	_	_	_	_
35	25	_	NUM	_	NumType=Card	_	_	_	_
36	microM	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	counter	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	anion	_	NOUN	_	Number=Sing	_	_	_	_
42	thioglucose	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	TG	_	NOUN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	or	_	CCONJ	_	_	_	_	_	_
47	gold	_	ADJ	_	Degree=Pos	_	_	_	_
48	compound	_	NOUN	_	Number=Sing	_	_	_	_
49	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
50	divalent	_	ADJ	_	Degree=Pos	_	_	_	_
51	gold	_	NOUN	_	Degree=Pos	_	_	_	_
52	ion	_	NOUN	_	Number=Sing	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	HAuCl3	_	PROPN	_	Number=Sing	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
57	no	_	DET	_	_	_	_	_	_
58	effect	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	AuTG	_	PROPN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	transient	_	ADJ	_	Degree=Pos	_	_	_	_
18	CAT	_	NOUN	_	Number=Sing	_	_	_	_
19	assay	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Specific	_	ADJ	_	Degree=Pos	_	_	_	_
2	staining	_	NOUN	_	Number=Sing	_	_	_	_
3	as	_	ADV	_	_	_	_	_	_
4	well	_	ADV	_	Degree=Pos	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	electron	_	ADJ	_	Degree=Pos	_	_	_	_
7	microscopic	_	ADJ	_	Degree=Pos	_	_	_	_
8	examinations	_	NOUN	_	Number=Plur	_	_	_	_
9	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	metal	_	NOUN	_	Number=Sing	_	_	_	_
14	gold	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	supporting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
21	previous	_	ADJ	_	Degree=Pos	_	_	_	_
22	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	SCONJ	_	PronType=Rel	_	_	_	_
24	gold	_	ADJ	_	Degree=Pos	_	_	_	_
25	ions	_	NOUN	_	Number=Plur	_	_	_	_
26	could	_	AUX	_	VerbForm=Fin	_	_	_	_
27	block	_	VERB	_	VerbForm=Inf	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	DNA	_	NOUN	_	Number=Sing	_	_	_	_
33	binding	_	VERB	_	Number=Sing	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	redox	_	NOUN	_	Number=Sing	_	_	_	_
37	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	monovalent	_	ADJ	_	Degree=Pos	_	_	_	_
7	gold	_	ADJ	_	Degree=Pos	_	_	_	_
8	compound	_	NOUN	_	Number=Sing	_	_	_	_
9	AuTG	_	PROPN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	potentially	_	ADV	_	_	_	_	_	_
13	useful	_	ADJ	_	Degree=Pos	_	_	_	_
14	drug	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	treatment	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	patients	_	NOUN	_	Number=Plur	_	_	_	_
20	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011088	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	T-lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	individuals	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	filarial	_	ADJ	_	Degree=Pos	_	_	_	_
6	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	disease	_	NOUN	_	Number=Sing	_	_	_	_
8	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	transendothelial	_	ADJ	_	Degree=Pos	_	_	_	_
11	migration	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vitro	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	vitro	_	PROPN	_	Number=Sing	_	_	_	_
4	transendothelial	_	NOUN	_	Number=Sing	_	_	_	_
5	migration	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	SCONJ	_	_	_	_	_	_
7	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	filarial	_	ADJ	_	Degree=Pos	_	_	_	_
9	antigen	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	Wuchereria	_	PROPN	_	Number=Sing	_	_	_	_
17	banerofti	_	NOUN	_	Degree=Pos	_	_	_	_
18	infection	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
2	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	individuals	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	filaria	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	lymphatic	_	ADJ	_	Number=Sing	_	_	_	_
10	pathology	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	LP	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	significantly	_	ADV	_	_	_	_	_	_
16	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
17	migration	_	NOUN	_	Number=Sing	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
20	HUVEC	_	ADJ	_	Number=Sing	_	_	_	_
21	monolayers	_	NOUN	_	Number=Plur	_	_	_	_
22	than	_	SCONJ	_	_	_	_	_	_
23	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	asymptomatic	_	ADJ	_	Degree=Pos	_	_	_	_
27	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	MF	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	individuals	_	NOUN	_	Number=Plur	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	P	_	NOUN	_	Number=Sing	_	_	_	_
34	=	_	SYM	_	_	_	_	_	_
35	0.04	_	NUM	_	NumType=Card	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	MF	_	NOUN	_	Number=Sing	_	_	_	_
6	individuals	_	NOUN	_	Number=Plur	_	_	_	_
7	where	_	ADV	_	PronType=Rel	_	_	_	_
8	no	_	DET	_	_	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	transendothelial	_	ADJ	_	Degree=Pos	_	_	_	_
14	migration	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	48	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	hr	_	NOUN	_	Number=Sing	_	_	_	_
19	filarial	_	ADJ	_	Degree=Pos	_	_	_	_
20	antigen	_	NOUN	_	Number=Sing	_	_	_	_
21	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	LP	_	NOUN	_	Number=Sing	_	_	_	_
25	individuals	_	NOUN	_	Number=Plur	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	significantly	_	ADV	_	_	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	P	_	NOUN	_	Number=Sing	_	_	_	_
30	=	_	SYM	_	_	_	_	_	_
31	0.01	_	NUM	_	NumType=Card	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
34	than	_	ADP	_	_	_	_	_	_
35	migration	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	48	_	NUM	_	NumType=Card	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	hr	_	NOUN	_	Number=Sing	_	_	_	_
40	media-stimulated	_	VERB	_	Degree=Pos	_	_	_	_
41	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	six	_	NUM	_	NumType=Card	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	seven	_	NUM	_	NumType=Card	_	_	_	_
5	patients	_	NOUN	_	Number=Plur	_	_	_	_
6	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	VLA-4/VCAM	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	pathway	_	NOUN	_	Number=Sing	_	_	_	_
15	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	50	_	NUM	_	NumType=Card	_	_	_	_
20	%	_	SYM	_	Number=Sing	_	_	_	_
21	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	transendothelial	_	ADJ	_	Degree=Pos	_	_	_	_
24	migration	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011090	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	low	_	ADJ	_	Degree=Pos	_	_	_	_
3	NM23.H1	_	NOUN	_	Number=Sing	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	identifying	_	VERB	_	VerbForm=Ger	_	_	_	_
7	high	_	ADJ	_	Degree=Pos	_	_	_	_
8	malignancy	_	NOUN	_	Number=Sing	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	melanomas	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NM23	_	PROPN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
6	proposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	metastasis	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	use	_	NOUN	_	Number=Sing	_	_	_	_
17	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
19	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	prognostic	_	ADJ	_	Degree=Pos	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	NM23	_	NOUN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	system	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	murine	_	ADJ	_	Number=Sing	_	_	_	_
9	melanoma	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	lines	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	inverse	_	ADJ	_	Degree=Pos	_	_	_	_
17	relationship	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	between	_	ADP	_	_	_	_	_	_
21	NM23	_	PROPN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	metastatic	_	ADJ	_	Degree=Pos	_	_	_	_
25	ability	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
5	melanoma	_	NOUN	_	Number=Sing	_	_	_	_
6	study	_	NOUN	_	Number=Sing	_	_	_	_
7	NM23	_	PROPN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	significantly	_	ADV	_	_	_	_	_	_
14	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	metastases	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	developed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	less	_	ADJ	_	Degree=Cmp	_	_	_	_
20	than	_	ADP	_	_	_	_	_	_
21	24	_	NUM	_	NumType=Card	_	_	_	_
22	months	_	NOUN	_	Number=Plur	_	_	_	_
23	after	_	ADP	_	_	_	_	_	_
24	diagnosis	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	primary	_	ADJ	_	Degree=Pos	_	_	_	_
28	tumours	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	paper	_	NOUN	_	Number=Sing	_	_	_	_
4	studies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	NM23	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	H1	_	NOUN	_	Degree=Pos	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	lines	_	NOUN	_	Number=Plur	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	derive	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	metastatic	_	ADJ	_	Degree=Pos	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
14	melanomas	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	relation	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	staging	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
21	degree	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
24	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	morphology	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	pigmentation	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	karyotype	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	disease	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	free	_	ADJ	_	Degree=Pos	_	_	_	_
38	survival	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	level	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NM23	_	PROPN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	significantly	_	ADV	_	_	_	_	_	_
12	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	lines	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	derive	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	more	_	ADV	_	_	_	_	_	_
20	infiltrating	_	VERB	_	Degree=Pos	_	_	_	_
21	primary	_	ADJ	_	Degree=Pos	_	_	_	_
22	melanomas	_	NOUN	_	Number=Plur	_	_	_	_
23	than	_	ADP	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	lines	_	NOUN	_	Number=Plur	_	_	_	_
27	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	less	_	ADV	_	Degree=Cmp	_	_	_	_
30	infiltrating	_	ADJ	_	Degree=Pos	_	_	_	_
31	tumours	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	tumours	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	patients	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	disease	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	free	_	ADJ	_	Degree=Pos	_	_	_	_
15	survival	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	more	_	ADJ	_	Degree=Cmp	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	24	_	NUM	_	NumType=Card	_	_	_	_
20	months	_	NOUN	_	Number=Plur	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	24	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	58	_	NUM	_	NumType=Card	_	_	_	_
25	months	_	NOUN	_	Number=Plur	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	express	_	VERB	_	VerbForm=Inf	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	NM23	_	NOUN	_	Number=Sing	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	at	_	ADP	_	_	_	_	_	_
32	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
33	levels	_	NOUN	_	Number=Plur	_	_	_	_
34	than	_	ADP	_	_	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	lines	_	NOUN	_	Number=Plur	_	_	_	_
37	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	from	_	ADP	_	_	_	_	_	_
39	melanomas	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	patients	_	NOUN	_	Number=Sing	_	_	_	_
42	with	_	ADP	_	_	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	disease	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	free	_	ADJ	_	Degree=Pos	_	_	_	_
47	survival	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	less	_	ADJ	_	Degree=Cmp	_	_	_	_
50	than	_	ADP	_	_	_	_	_	_
51	24	_	NUM	_	NumType=Card	_	_	_	_
52	months	_	NOUN	_	Number=Plur	_	_	_	_
53	(	_	PUNCT	_	_	_	_	_	_
54	6	_	NUM	_	NumType=Card	_	_	_	_
55	-	_	SYM	_	_	_	_	_	_
56	15	_	NUM	_	NumType=Card	_	_	_	_
57	months	_	NOUN	_	Number=Plur	_	_	_	_
58	)	_	PUNCT	_	_	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011093	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tissue	_	NOUN	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	lysophosphatidylcholine	_	PROPN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	tissue	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	TF	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	principal	_	ADJ	_	Degree=Pos	_	_	_	_
12	initiator	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	coagulation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	during	_	ADP	_	_	_	_	_	_
19	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	conditions	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	promoted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	lysophosphatidylcholine	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	lysoPC	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	present	_	ADJ	_	Degree=Pos	_	_	_	_
6	study	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	DET	_	PronType=Rel	_	_	_	_
8	lysoPC	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	10	_	NUM	_	NumType=Card	_	_	_	_
13	micromol	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	L	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	dose	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependently	_	ADV	_	_	_	_	_	_
20	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	TF	_	ADJ	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	as	_	SCONJ	_	_	_	_	_	_
28	elicited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	LPS	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Lysophosphatidylethanolamine	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	lysoPE	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	lysophospholipids	_	NOUN	_	Number=Plur	_	_	_	_
8	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
11	LPS	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	TF	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	TF	_	ADP	_	_	_	_	_	_
2	antigen	_	ADJ	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	as	_	SCONJ	_	_	_	_	_	_
5	elicited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	LPS	_	PROPN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	lowered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	lysoPC	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Phospholipid	_	ADJ	_	Number=Sing	_	_	_	_
2	analyses	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	selective	_	ADJ	_	Degree=Pos	_	_	_	_
6	increase	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	lysoPC	_	NOUN	_	Number=Sing	_	_	_	_
10	content	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	after	_	ADP	_	_	_	_	_	_
15	preincubation	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	lysophospholipid	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	LysoPC	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	TF	_	PROPN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Mono	_	PROPN	_	Number=Sing	_	_	_	_
8	Mac	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	similar	_	ADJ	_	Degree=Pos	_	_	_	_
15	extent	_	NOUN	_	Number=Sing	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	NOUN	_	Number=Sing	_	_	_	_
2	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	plasma	_	NOUN	_	Number=Sing	_	_	_	_
5	membrane	_	NOUN	_	Number=Sing	_	_	_	_
6	receptors	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	internalization	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	LPS	_	NOUN	_	Number=Plur	_	_	_	_
11	into	_	ADP	_	_	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	lysoPC	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	LPS	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	Rel	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	TF	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	lysoPC	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TF	_	PROPN	_	Number=Sing	_	_	_	_
4	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	LPS	_	NOUN	_	Number=Sing	_	_	_	_
8	tended	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	partially	_	ADV	_	_	_	_	_	_
12	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	lysophospholipid	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Preincubation	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	lysoPC	_	NOUN	_	Number=Sing	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
6	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	adenylyl	_	NOUN	_	Number=Sing	_	_	_	_
4	cyclase	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	2'-	_	NUM	_	NumType=Card	_	_	_	_
9	deoxy	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	'-	_	PUNCT	_	_	_	_	_	_
13	adenosine	_	ADJ	_	Degree=Pos	_	_	_	_
14	monophosphate	_	NOUN	_	Number=Sing	_	_	_	_
15	partially	_	ADV	_	_	_	_	_	_
16	reversed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	TF	_	PROPN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	promoted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	lysoPC	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	lysoPC	_	NOUN	_	Number=Sing	_	_	_	_
5	markedly	_	ADV	_	_	_	_	_	_
6	decreases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	LPS	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	TF	_	ADP	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	effect	_	NOUN	_	Number=Sing	_	_	_	_
18	probably	_	ADV	_	_	_	_	_	_
19	being	_	AUX	_	VerbForm=Ger	_	_	_	_
20	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
26	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	LysoPC	_	PROPN	_	Number=Sing	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	thus	_	ADV	_	_	_	_	_	_
4	attenuate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	coagulation	_	NOUN	_	Number=Sing	_	_	_	_
8	during	_	ADP	_	_	_	_	_	_
9	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011094	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	independent	_	ADJ	_	Degree=Pos	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	CD28	_	PROPN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	role	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	CD28	_	PROPN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	firmly	_	ADV	_	_	_	_	_	_
12	established	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
19	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	actions	_	NOUN	_	Number=Plur	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	less	_	ADV	_	Degree=Cmp	_	_	_	_
25	clear	_	ADJ	_	Degree=Pos	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	many	_	ADJ	_	Degree=Pos	_	_	_	_
3	circumstances	_	NOUN	_	Number=Plur	_	_	_	_
4	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	difficult	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	distinguish	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	effects	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	CD28	_	NOUN	_	Number=Sing	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
15	actions	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	such	_	ADJ	_	Degree=Pos	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	T	_	NOUN	_	NumType=Card	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	model	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	CD28	_	PROPN	_	Number=Sing	_	_	_	_
9	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	using	_	VERB	_	VerbForm=Ger	_	_	_	_
11	PMA	_	PROPN	_	Number=Sing	_	_	_	_
12	plus	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	natural	_	ADJ	_	Degree=Pos	_	_	_	_
15	ligand	_	NOUN	_	Number=Sing	_	_	_	_
16	CD80	_	PROPN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	very	_	ADV	_	_	_	_	_	_
21	limited	_	ADJ	_	Degree=Pos	_	_	_	_
22	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	as	_	SCONJ	_	_	_	_	_	_
29	evidenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	both	_	DET	_	_	_	_	_	_
32	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
33	production	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	promoter	_	NOUN	_	Number=Sing	_	_	_	_
39	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Promoter	_	NOUN	_	Number=Sing	_	_	_	_
2	assays	_	NOUN	_	Number=Plur	_	_	_	_
3	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	CD28	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	but	_	CCONJ	_	_	_	_	_	_
19	not	_	ADV	_	_	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	AT	_	ADP	_	_	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	intact	_	NOUN	_	Degree=Pos	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	completely	_	ADV	_	_	_	_	_	_
9	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	actions	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	immunosuppressant	_	ADJ	_	Degree=Pos	_	_	_	_
16	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
17	A	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	CsA	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	T	_	DET	_	NumType=Card	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	unaffected	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	addition	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
12	Abs	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	form	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	CD28	_	PROPN	_	Number=Sing	_	_	_	_
33	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
34	independent	_	ADJ	_	Degree=Pos	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	SCONJ	_	_	_	_	_	_
7	stimulating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	blasts	_	NOUN	_	Number=Plur	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	CD80	_	NOUN	_	Number=Sing	_	_	_	_
13	alone	_	ADV	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	there	_	PRON	_	_	_	_	_	_
18	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	limited	_	ADJ	_	Degree=Pos	_	_	_	_
21	requirement	_	NOUN	_	Number=Sing	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	system	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	CD28	_	PROPN	_	Number=Sing	_	_	_	_
5	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	cause	_	VERB	_	VerbForm=Inf	_	_	_	_
8	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	absence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	driven	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	independent	_	ADJ	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	AT	_	ADP	_	_	_	_	_	_
32	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011097	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
7	components	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	AT	_	ADP	_	_	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	complex	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	complex	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	AT	_	ADP	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	involved	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	early	_	ADJ	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	assembled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	pre-existing	_	ADJ	_	Degree=Pos	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
36	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
37	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
38	component	_	NOUN	_	Number=Sing	_	_	_	_
39	within	_	ADP	_	_	_	_	_	_
40	30	_	NUM	_	NumType=Card	_	_	_	_
41	min	_	NOUN	_	Number=Plur	_	_	_	_
42	after	_	ADP	_	_	_	_	_	_
43	activation	_	NOUN	_	Number=Sing	_	_	_	_
44	through	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	antigen	_	NOUN	_	Number=Sing	_	_	_	_
47	receptor	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	implicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	family	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	AP1	_	NOUN	_	Number=Sing	_	_	_	_
9	factors	_	NOUN	_	Number=Plur	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	components	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	murine	_	NOUN	_	Number=Sing	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	AT	_	ADP	_	_	_	_	_	_
18	complex	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	provided	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	here	_	ADV	_	PronType=Dem	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	component	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	AT	_	PROPN	_	_	_	_	_	_
14	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
17	ester	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	AP1	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	Jun	_	PROPN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	Fos	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	characterize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	which	_	PRON	_	PronType=Int	_	_	_	_
5	AP1	_	NOUN	_	Number=Sing	_	_	_	_
6	family	_	NOUN	_	Number=Sing	_	_	_	_
7	members	_	NOUN	_	Number=Plur	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	assume	_	VERB	_	VerbForm=Inf	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Antisera	_	PROPN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	Fos	_	PROPN	_	Number=Sing	_	_	_	_
4	inhibits	_	VERB	_	Number=Sing	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	AT	_	ADP	_	_	_	_	_	_
8	DNA	_	PROPN	_	Number=Sing	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	as	_	SCONJ	_	_	_	_	_	_
11	does	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
14	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	site	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	AP1	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vivo	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Fos	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	lesser	_	ADJ	_	Degree=Cmp	_	_	_	_
12	extent	_	NOUN	_	Number=Sing	_	_	_	_
13	Fra-1	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	eliminates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	requirement	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
20	12	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	myristate	_	NOUN	_	Number=Sing	_	_	_	_
23	13	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	acetate	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	PMA	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	leaving	_	VERB	_	VerbForm=Ger	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	AT	_	ADP	_	_	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	responsive	_	ADJ	_	Number=Sing	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	calcium	_	VERB	_	Number=Sing	_	_	_	_
41	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
42	alone	_	ADV	_	_	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cJun	_	PROPN	_	Number=Sing	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	JunD	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	but	_	CCONJ	_	_	_	_	_	_
8	not	_	ADV	_	_	_	_	_	_
9	JunB	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	eliminates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	requirement	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	PMA	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	many	_	ADJ	_	Degree=Pos	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	not	_	ADV	_	_	_	_	_	_
23	all	_	DET	_	_	_	_	_	_
24	Jun	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	Fos	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	related	_	ADJ	_	Degree=Pos	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	functionally	_	ADV	_	_	_	_	_	_
32	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	AT	_	ADP	_	_	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	presence	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
45	component	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	AT	_	ADP	_	_	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	reconstituted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vitro	_	NOUN	_	Number=Sing	_	_	_	_
11	using	_	VERB	_	VerbForm=Ger	_	_	_	_
12	semi	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	AP1	_	NOUN	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	mixed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Fos	_	PROPN	_	Number=Sing	_	_	_	_
2	proteins	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	needed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	reconstitution	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	although	_	SCONJ	_	_	_	_	_	_
12	JunB	_	PROPN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	functional	_	ADJ	_	Degree=Pos	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
18	can	_	AUX	_	VerbForm=Fin	_	_	_	_
19	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	AT	_	ADP	_	_	_	_	_	_
25	DNA	_	PROPN	_	Number=Sing	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	complex	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	partially	_	ADV	_	_	_	_	_	_
6	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
9	component	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	AT	_	ADP	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	show	_	VERB	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	elution	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	renaturation	_	NOUN	_	Number=Sing	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	SDS	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	polyacrylamide	_	ADJ	_	Number=Sing	_	_	_	_
24	gel	_	NOUN	_	Number=Sing	_	_	_	_
25	electrophoresis	_	NOUN	_	Number=Sing	_	_	_	_
26	gels	_	NOUN	_	Number=Plur	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
29	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
32	mass	_	NOUN	_	Number=Sing	_	_	_	_
33	between	_	ADP	_	_	_	_	_	_
34	94	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	116	_	NUM	_	NumType=Card	_	_	_	_
37	kDa	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	may	_	AUX	_	VerbForm=Fin	_	_	_	_
40	have	_	VERB	_	VerbForm=Inf	_	_	_	_
41	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
42	differentially	_	ADV	_	_	_	_	_	_
43	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	forms	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011099	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Amelioration	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	rat	_	NOUN	_	Number=Sing	_	_	_	_
4	cerulein	_	NOUN	_	Number=Sing	_	_	_	_
5	pancreatitis	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	guamerin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	peptide	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	novel	_	NOUN	_	Number=Sing	_	_	_	_
14	elastase	_	NOUN	_	Number=Sing	_	_	_	_
15	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	various	_	ADJ	_	Degree=Pos	_	_	_	_
5	proteases	_	NOUN	_	Number=Plur	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	experimental	_	ADJ	_	Degree=Pos	_	_	_	_
13	pancreatitis	_	NOUN	_	Number=Sing	_	_	_	_
14	;	_	PUNCT	_	_	_	_	_	_
15	however	_	ADV	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	information	_	NOUN	_	Number=Sing	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	effects	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	protease	_	NOUN	_	Number=Sing	_	_	_	_
25	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	disease	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	limited	_	ADJ	_	Degree=Pos	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	novel	_	NOUN	_	Number=Sing	_	_	_	_
9	elastase	_	NOUN	_	Number=Sing	_	_	_	_
10	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	guamerin	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
16	peptide	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	GDSP	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	improves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	parameters	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	cerulein	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	acute	_	ADJ	_	Degree=Pos	_	_	_	_
29	pancreatitis	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	rat	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	GDSP	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	pancreatic	_	ADJ	_	Degree=Pos	_	_	_	_
7	weight	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	serum	_	NOUN	_	Number=Sing	_	_	_	_
10	amylase	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	lipase	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	morphologic	_	ADJ	_	Degree=Pos	_	_	_	_
15	changes	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	pancreas	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	neutrophil	_	NOUN	_	Degree=Pos	_	_	_	_
21	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	KB	_	PROPN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	KB	_	PROPN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	rats	_	NOUN	_	Number=Plur	_	_	_	_
37	infused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	supramaximal	_	ADJ	_	Degree=Pos	_	_	_	_
40	dose	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	cerulein	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	5	_	NUM	_	NumType=Card	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	g	_	NOUN	_	Number=Sing	_	_	_	_
47	/	_	SYM	_	_	_	_	_	_
48	kg	_	NOUN	_	Number=Sing	_	_	_	_
49	/	_	SYM	_	_	_	_	_	_
50	h	_	NOUN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	for	_	ADP	_	_	_	_	_	_
53	6	_	NUM	_	NumType=Card	_	_	_	_
54	h	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	GDSP	_	PROPN	_	Number=Sing	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	superoxide	_	NOUN	_	Number=Sing	_	_	_	_
10	formation	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	GDSP	_	PROPN	_	Number=Sing	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	another	_	DET	_	_	_	_	_	_
11	elastase	_	NOUN	_	Number=Sing	_	_	_	_
12	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	elastatinal	_	ADJ	_	Degree=Pos	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	GDSP	_	PROPN	_	Number=Sing	_	_	_	_
2	significantly	_	ADV	_	_	_	_	_	_
3	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	edema	_	NOUN	_	Number=Sing	_	_	_	_
5	formation	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
8	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	acinar	_	ADJ	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	damage	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	plasma	_	NOUN	_	Number=Sing	_	_	_	_
16	lipase	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	amylase	_	NOUN	_	Number=Sing	_	_	_	_
19	increases	_	NOUN	_	Number=Plur	_	_	_	_
20	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	cerulein	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	GDSP	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	completely	_	ADV	_	_	_	_	_	_
4	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	superoxide	_	NOUN	_	Number=Sing	_	_	_	_
6	formation	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
11	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	N-formyl	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	methionine	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	leucine	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	phenyl	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alanine	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	fMLP	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	13	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	acetate	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	TPA	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Elastatinal	_	PROPN	_	Number=Sing	_	_	_	_
2	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	some	_	DET	_	_	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	same	_	ADJ	_	Degree=Pos	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	GDSP	_	NOUN	_	Number=Sing	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	less	_	ADV	_	Degree=Cmp	_	_	_	_
13	potent	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	effective	_	ADJ	_	Degree=Pos	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	beneficial	_	ADJ	_	Degree=Pos	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	GDSP	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	novel	_	NOUN	_	Number=Sing	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	elastase	_	NOUN	_	Number=Sing	_	_	_	_
14	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	development	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	rat	_	NOUN	_	Number=Sing	_	_	_	_
21	cerulein	_	NOUN	_	Number=Sing	_	_	_	_
22	pancreatitis	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011100	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
3	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	GH	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	N	_	NOUN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	Pit	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1b	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	GH	_	PROPN	_	Number=Sing	_	_	_	_
3	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	development	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	function	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	GH	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	subsets	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	immunocytochemistry	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	25	_	NUM	_	NumType=Card	_	_	_	_
5	+/-	_	SYM	_	_	_	_	_	_
6	7	_	NUM	_	NumType=Card	_	_	_	_
7	%	_	SYM	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	express	_	VERB	_	Degree=Pos	_	_	_	_
16	immunoreactive	_	ADJ	_	Degree=Pos	_	_	_	_
17	GH	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	whereas	_	SCONJ	_	_	_	_	_	_
20	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	negative	_	ADJ	_	Degree=Pos	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Reversed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	RT	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	PCR	_	NOUN	_	Number=Sing	_	_	_	_
8	analysis	_	NOUN	_	Number=Sing	_	_	_	_
9	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	GH	_	PROPN	_	Number=Sing	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Restriction	_	NOUN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
6	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	GH	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	N	_	PROPN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	GH	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	V	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	western	_	ADJ	_	Degree=Pos	_	_	_	_
7	blot	_	NOUN	_	Number=Sing	_	_	_	_
8	analysis	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
11	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	alternatively	_	ADV	_	_	_	_	_	_
14	spliced	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
15	variant	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	pituitary	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	Pit	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	Pit	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1b	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011104	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	N	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	C	_	X	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
7	sequences	_	NOUN	_	Number=Plur	_	_	_	_
8	control	_	NOUN	_	Number=Sing	_	_	_	_
9	degradation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	MAD3	_	PROPN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	kappa	_	VERB	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	inducers	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
3	degradation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	MAD3	_	PROPN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	kappa	_	VERB	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	prerequisite	_	ADJ	_	Degree=Pos	_	_	_	_
22	step	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	PROPN	_	Number=Sing	_	_	_	_
33	B.	_	PROPN	_	Number=Sing	_	_	_	_
34	Analysis	_	PROPN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	expression	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	human	_	ADJ	_	Degree=Pos	_	_	_	_
40	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
41	kappa	_	VERB	_	Number=Sing	_	_	_	_
42	B	_	PROPN	_	Number=Sing	_	_	_	_
43	alpha	_	NOUN	_	Number=Sing	_	_	_	_
44	protein	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	stable	_	ADJ	_	Degree=Pos	_	_	_	_
47	transfectants	_	NOUN	_	Number=Plur	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	mouse	_	NOUN	_	Number=Sing	_	_	_	_
50	70Z	_	PROPN	_	Number=Sing	_	_	_	_
51	/	_	PUNCT	_	_	_	_	_	_
52	3	_	NUM	_	NumType=Card	_	_	_	_
53	cells	_	NOUN	_	Number=Plur	_	_	_	_
54	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
55	that	_	SCONJ	_	_	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	as	_	ADP	_	_	_	_	_	_
58	for	_	ADP	_	_	_	_	_	_
59	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
60	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
61	murine	_	NOUN	_	Number=Sing	_	_	_	_
62	protein	_	NOUN	_	Number=Sing	_	_	_	_
63	,	_	PUNCT	_	_	_	_	_	_
64	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
65	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
66	kappa	_	VERB	_	Number=Sing	_	_	_	_
67	B	_	PROPN	_	Number=Sing	_	_	_	_
68	alpha	_	NOUN	_	Number=Sing	_	_	_	_
69	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
70	degraded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
71	in	_	ADP	_	_	_	_	_	_
72	response	_	NOUN	_	Number=Sing	_	_	_	_
73	to	_	ADP	_	_	_	_	_	_
74	inducers	_	NOUN	_	Number=Plur	_	_	_	_
75	of	_	ADP	_	_	_	_	_	_
76	NF	_	PROPN	_	Number=Sing	_	_	_	_
77	-	_	PUNCT	_	_	_	_	_	_
78	kappa	_	NOUN	_	Number=Sing	_	_	_	_
79	B	_	NOUN	_	Number=Sing	_	_	_	_
80	activity	_	NOUN	_	Number=Sing	_	_	_	_
81	,	_	PUNCT	_	_	_	_	_	_
82	such	_	ADJ	_	Degree=Pos	_	_	_	_
83	as	_	ADP	_	_	_	_	_	_
84	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
85	myristate	_	NOUN	_	Number=Sing	_	_	_	_
86	acetate	_	NOUN	_	Number=Sing	_	_	_	_
87	or	_	CCONJ	_	_	_	_	_	_
88	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
89	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	proteasome	_	NOUN	_	Degree=Pos	_	_	_	_
11	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
12	N-Ac	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	Leu	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	Leu	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	norleucinal	_	ADJ	_	Degree=Pos	_	_	_	_
19	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	ligand	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	degradation	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	agreement	_	NOUN	_	Number=Sing	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	previous	_	ADJ	_	Degree=Pos	_	_	_	_
31	studies	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	stabilizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	hyperphosphorylated	_	ADJ	_	Degree=Pos	_	_	_	_
36	form	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	human	_	ADJ	_	Degree=Pos	_	_	_	_
40	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
41	kappa	_	VERB	_	Number=Sing	_	_	_	_
42	B	_	PROPN	_	Number=Sing	_	_	_	_
43	alpha	_	NOUN	_	Number=Sing	_	_	_	_
44	protein	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
4	forms	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	line	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	able	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	delineate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	sequences	_	NOUN	_	Number=Plur	_	_	_	_
22	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	both	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	ligand	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	degradation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
35	kappa	_	VERB	_	Number=Sing	_	_	_	_
36	B	_	PROPN	_	Number=Sing	_	_	_	_
37	alpha	_	PROPN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	deletion	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	C	_	NOUN	_	Number=Sing	_	_	_	_
9	terminus	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	I	_	PRON	_	NumType=Card	_	_	_	_
13	kappa	_	VERB	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	molecule	_	NOUN	_	Number=Sing	_	_	_	_
17	up	_	ADP	_	_	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	amino	_	NOUN	_	Number=Sing	_	_	_	_
20	acid	_	NOUN	_	Number=Sing	_	_	_	_
21	279	_	NUM	_	NumType=Card	_	_	_	_
22	abolishes	_	NOUN	_	Number=Plur	_	_	_	_
23	constitutive	_	NOUN	_	Number=Sing	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	ligand	_	ADJ	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
29	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	inhibits	_	VERB	_	Degree=Pos	_	_	_	_
32	ligand	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
35	degradation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	reveals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	kappa	_	VERB	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	maps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	serines	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	N	_	PROPN	_	Number=Sing	_	_	_	_
20	terminus	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	residues	_	NOUN	_	Number=Plur	_	_	_	_
26	32	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	36	_	NUM	_	NumType=Card	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	mutation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	either	_	DET	_	_	_	_	_	_
36	residue	_	NOUN	_	Number=Sing	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
39	to	_	PART	_	_	_	_	_	_
40	abolish	_	VERB	_	VerbForm=Inf	_	_	_	_
41	ligand	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	degradation	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	whereas	_	SCONJ	_	_	_	_	_	_
47	both	_	DET	_	_	_	_	_	_
48	residues	_	NOUN	_	Number=Plur	_	_	_	_
49	must	_	AUX	_	VerbForm=Fin	_	_	_	_
50	be	_	AUX	_	VerbForm=Inf	_	_	_	_
51	mutated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	to	_	PART	_	_	_	_	_	_
53	abolish	_	VERB	_	VerbForm=Inf	_	_	_	_
54	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
55	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
58	protein	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	0030011106	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	growth	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
8	MCM5	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	MCM6	_	PROPN	_	Number=Sing	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	E2F	_	PROPN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Initiation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	DNA	_	NOUN	_	Number=Sing	_	_	_	_
4	replication	_	NOUN	_	Number=Sing	_	_	_	_
5	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	function	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	MCM	_	PROPN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	products	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	participate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	in	_	SCONJ	_	_	_	_	_	_
16	ensuring	_	VERB	_	VerbForm=Ger	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	DNA	_	PROPN	_	Number=Sing	_	_	_	_
19	replication	_	NOUN	_	Number=Sing	_	_	_	_
20	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	only	_	ADV	_	_	_	_	_	_
22	once	_	ADV	_	NumType=Mult	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	cycle	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	all	_	DET	_	_	_	_	_	_
4	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
5	genes	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	MCM	_	PROPN	_	Number=Sing	_	_	_	_
9	family	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	growth	_	NOUN	_	Number=Sing	_	_	_	_
14	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	unlike	_	ADP	_	_	_	_	_	_
17	yeast	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
22	levels	_	NOUN	_	Number=Plur	_	_	_	_
23	peak	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	at	_	ADP	_	_	_	_	_	_
25	G1	_	PROPN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	S	_	PROPN	_	Number=Sing	_	_	_	_
28	boundary	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	activities	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	MCM	_	NOUN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	promoters	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	MCM5	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	MCM6	_	PROPN	_	Number=Sing	_	_	_	_
5	promoters	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	mutation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	E2F	_	NOUN	_	Number=Sing	_	_	_	_
11	sites	_	NOUN	_	Number=Plur	_	_	_	_
12	failed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	promoter	_	VERB	_	Degree=Pos	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	following	_	VERB	_	VerbForm=Ger	_	_	_	_
17	serum	_	NOUN	_	Number=Sing	_	_	_	_
18	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
21	E2F	_	PROPN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	novel	_	NOUN	_	Number=Sing	_	_	_	_
8	E2F	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	like	_	ADJ	_	Degree=Pos	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	MCM6	_	PROPN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	cooperates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	authentic	_	ADJ	_	Degree=Pos	_	_	_	_
21	E2F	_	NOUN	_	Number=Sing	_	_	_	_
22	sites	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	E2F	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	regulation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Forced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	E2F1	_	NOUN	_	Number=Sing	_	_	_	_
5	could	_	AUX	_	VerbForm=Fin	_	_	_	_
6	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	all	_	DET	_	_	_	_	_	_
10	members	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
14	MCM	_	PROPN	_	Number=Sing	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	rat	_	NOUN	_	Number=Sing	_	_	_	_
18	embryonal	_	ADJ	_	Degree=Pos	_	_	_	_
19	fibroblast	_	NOUN	_	Number=Sing	_	_	_	_
20	REF52	_	NUM	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	growth	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
12	MCM5	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	MCM6	_	PROPN	_	Number=Sing	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	presumably	_	ADV	_	_	_	_	_	_
19	other	_	ADJ	_	Degree=Pos	_	_	_	_
20	MCM	_	NOUN	_	Number=Sing	_	_	_	_
21	members	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	primarily	_	ADV	_	_	_	_	_	_
25	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	E2F	_	PROPN	_	Number=Sing	_	_	_	_
28	through	_	ADP	_	_	_	_	_	_
29	binding	_	VERB	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
32	E2F	_	NOUN	_	Number=Sing	_	_	_	_
33	sites	_	NOUN	_	Number=Plur	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	promoters	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011110	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cyclosporin	_	VERB	_	Number=Sing	_	_	_	_
2	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	inhibits	_	NOUN	_	Degree=Pos	_	_	_	_
4	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
5	tissue	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	cardiac	_	ADJ	_	Degree=Pos	_	_	_	_
10	transplant	_	NOUN	_	Number=Sing	_	_	_	_
11	recipients	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Fibrin	_	ADJ	_	Number=Sing	_	_	_	_
4	deposition	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	thrombosis	_	NOUN	_	Number=Sing	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
9	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	allograft	_	NOUN	_	Number=Sing	_	_	_	_
13	rejection	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	vasculopathy	_	NOUN	_	Number=Sing	_	_	_	_
16	after	_	ADP	_	_	_	_	_	_
17	cardiac	_	ADJ	_	Degree=Pos	_	_	_	_
18	transplantation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	pivotal	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	pathophysiology	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	intravascular	_	ADJ	_	Degree=Pos	_	_	_	_
12	coagulation	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	ability	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	synthesize	_	VERB	_	VerbForm=Inf	_	_	_	_
19	tissue	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	TF	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
26	asked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	1	_	X	_	_	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	whether	_	SCONJ	_	_	_	_	_	_
31	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
32	TF	_	PROPN	_	Number=Sing	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	cardiac	_	ADJ	_	Degree=Pos	_	_	_	_
37	transplant	_	NOUN	_	Number=Sing	_	_	_	_
38	recipients	_	NOUN	_	Number=Plur	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	2	_	X	_	_	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	whether	_	SCONJ	_	_	_	_	_	_
44	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
45	TF	_	PROPN	_	Number=Sing	_	_	_	_
46	expression	_	NOUN	_	Number=Sing	_	_	_	_
47	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
48	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
49	by	_	ADP	_	_	_	_	_	_
50	treatment	_	NOUN	_	Number=Sing	_	_	_	_
51	with	_	ADP	_	_	_	_	_	_
52	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
53	A	_	NOUN	_	Number=Sing	_	_	_	_
54	(	_	PUNCT	_	_	_	_	_	_
55	CsA	_	NOUN	_	Number=Sing	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	AND	_	CCONJ	_	_	_	_	_	_
3	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	measured	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	TF	_	PROPN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
9	blood	_	NOUN	_	Number=Sing	_	_	_	_
10	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	highly	_	ADV	_	_	_	_	_	_
14	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	10	_	NUM	_	NumType=Card	_	_	_	_
20	consecutive	_	ADJ	_	Degree=Pos	_	_	_	_
21	cardiac	_	ADJ	_	Degree=Pos	_	_	_	_
22	transplant	_	NOUN	_	Number=Sing	_	_	_	_
23	recipients	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	10	_	NUM	_	NumType=Card	_	_	_	_
26	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
27	control	_	NOUN	_	Number=Sing	_	_	_	_
28	subjects	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	TF	_	DET	_	Number=Sing	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	both	_	DET	_	_	_	_	_	_
6	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	endotoxin	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	significantly	_	ADV	_	_	_	_	_	_
14	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	transplant	_	ADJ	_	Degree=Pos	_	_	_	_
17	recipients	_	NOUN	_	Number=Plur	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	control	_	NOUN	_	Number=Sing	_	_	_	_
21	subjects	_	NOUN	_	Number=Plur	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	P<.05	_	NOUN	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
3	TF	_	NOUN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	transplant	_	ADJ	_	Degree=Pos	_	_	_	_
7	recipients	_	NOUN	_	Number=Plur	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	adversely	_	ADV	_	_	_	_	_	_
13	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	treatment	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	CsA	_	NOUN	_	Number=Sing	_	_	_	_
18	:	_	PUNCT	_	_	_	_	_	_
19	TF	_	PROPN	_	Number=Sing	_	_	_	_
20	induction	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	markedly	_	ADV	_	_	_	_	_	_
23	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	CsA	_	PROPN	_	Number=Sing	_	_	_	_
26	serum	_	NOUN	_	Number=Sing	_	_	_	_
27	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
28	reaching	_	VERB	_	VerbForm=Ger	_	_	_	_
29	peak	_	NOUN	_	Number=Sing	_	_	_	_
30	CsA	_	NOUN	_	Number=Sing	_	_	_	_
31	drug	_	NOUN	_	Number=Sing	_	_	_	_
32	levels	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TF	_	PROPN	_	Number=Sing	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	presence	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	high	_	ADJ	_	Degree=Pos	_	_	_	_
10	CsA	_	PROPN	_	Number=Sing	_	_	_	_
11	blood	_	NOUN	_	Number=Sing	_	_	_	_
12	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	when	_	ADV	_	PronType=Int	_	_	_	_
17	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	interferon	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	gamma	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1beta	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	reverse	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
8	chain	_	NOUN	_	Number=Sing	_	_	_	_
9	reaction	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
12	mobility	_	NOUN	_	Number=Sing	_	_	_	_
13	shift	_	NOUN	_	Number=Sing	_	_	_	_
14	assay	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	respectively	_	ADV	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	treatment	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	CsA	_	NOUN	_	Number=Sing	_	_	_	_
21	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	TF	_	PROPN	_	_	_	_	_	_
25	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	factor	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	which	_	PRON	_	PronType=Rel	_	_	_	_
39	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	to	_	PART	_	_	_	_	_	_
42	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	induction	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	TF	_	NOUN	_	Number=Sing	_	_	_	_
49	promotor	_	NOUN	_	Number=Sing	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	human	_	ADJ	_	Degree=Pos	_	_	_	_
52	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TF	_	PROPN	_	Number=Sing	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	cardiac	_	ADJ	_	Degree=Pos	_	_	_	_
14	transplant	_	NOUN	_	Number=Sing	_	_	_	_
15	recipients	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	treatment	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	CsA	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
4	TF	_	PROPN	_	Number=Sing	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	CsA	_	PROPN	_	Number=Sing	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	successful	_	ADJ	_	Degree=Pos	_	_	_	_
13	use	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	cardiac	_	ADJ	_	Degree=Pos	_	_	_	_
16	transplant	_	NOUN	_	Number=Sing	_	_	_	_
17	medicine	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	might	_	AUX	_	VerbForm=Fin	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	useful	_	ADJ	_	Degree=Pos	_	_	_	_
22	in	_	SCONJ	_	_	_	_	_	_
23	managing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	further	_	ADJ	_	Degree=Pos	_	_	_	_
25	settings	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
28	pathology	_	NOUN	_	Number=Sing	_	_	_	_
29	also	_	ADV	_	_	_	_	_	_
30	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
33	TF	_	PROPN	_	Number=Sing	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011112	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	c-Maf	_	NOUN	_	Number=Sing	_	_	_	_
2	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
4	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	bipotent	_	ADJ	_	Degree=Pos	_	_	_	_
9	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
10	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	drive	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	colony	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
9	unit	_	NOUN	_	Number=Sing	_	_	_	_
10	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	CFU	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	GM	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
19	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	into	_	ADP	_	_	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	either	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	granulocytic	_	NOUN	_	Number=Sing	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
30	lineage	_	NOUN	_	Number=Sing	_	_	_	_
31	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	not	_	PART	_	_	_	_	_	_
33	fully	_	ADV	_	_	_	_	_	_
34	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	c-Maf	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	c-Myb	_	NOUN	_	Number=Sing	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	physically	_	ADV	_	_	_	_	_	_
12	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	form	_	VERB	_	VerbForm=Inf	_	_	_	_
18	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
19	complexes	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	hinder	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	c	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	Myb	_	NOUN	_	Degree=Pos	_	_	_	_
27	target	_	NOUN	_	Number=Sing	_	_	_	_
28	genes	_	NOUN	_	Number=Plur	_	_	_	_
29	through	_	ADP	_	_	_	_	_	_
30	direct	_	ADJ	_	Degree=Pos	_	_	_	_
31	binding	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	Myb	_	VERB	_	VerbForm=Inf	_	_	_	_
34	consensus	_	NOUN	_	Number=Sing	_	_	_	_
35	sites	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	complexes	_	NOUN	_	Number=Plur	_	_	_	_
3	arise	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	developmentally	_	ADV	_	_	_	_	_	_
7	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	pattern	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	peaking	_	VERB	_	VerbForm=Ger	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	promyelocyte	_	NOUN	_	Number=Sing	_	_	_	_
14	stage	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	model	_	NOUN	_	Number=Sing	_	_	_	_
20	systems	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	appearing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	soon	_	ADV	_	Degree=Pos	_	_	_	_
24	after	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	induction	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
29	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	wished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
5	if	_	SCONJ	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	developmentally	_	ADV	_	_	_	_	_	_
8	related	_	VERB	_	Degree=Pos	_	_	_	_
9	interaction	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	consequence	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	intrinsic	_	ADJ	_	Degree=Pos	_	_	_	_
19	differentiating	_	NOUN	_	Number=Sing	_	_	_	_
20	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	elevated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
4	Myb:Maf	_	NOUN	_	Number=Sing	_	_	_	_
5	status	_	NOUN	_	Number=Sing	_	_	_	_
6	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	differentiating	_	ADJ	_	VerbForm=Ger	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	recapitulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	c-Maf	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	lines	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
23	inducibly	_	ADV	_	_	_	_	_	_
24	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	c-Maf	_	NOUN	_	Number=Sing	_	_	_	_
27	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	bipotent	_	ADJ	_	Degree=Pos	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
33	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	Maf	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	increases	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	Myb:Maf	_	NOUN	_	Number=Sing	_	_	_	_
14	complexes	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	eventual	_	ADJ	_	Degree=Pos	_	_	_	_
27	programmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	death	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	targets	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	could	_	AUX	_	VerbForm=Fin	_	_	_	_
6	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
9	changes	_	NOUN	_	Number=Plur	_	_	_	_
10	indicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	c-Maf	_	NOUN	_	Number=Sing	_	_	_	_
13	likely	_	ADV	_	_	_	_	_	_
14	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	key	_	ADJ	_	Degree=Pos	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	development	_	NOUN	_	Number=Sing	_	_	_	_
22	through	_	ADP	_	_	_	_	_	_
23	dual	_	ADJ	_	Degree=Pos	_	_	_	_
24	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
25	;	_	PUNCT	_	_	_	_	_	_
26	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	select	_	ADJ	_	Degree=Pos	_	_	_	_
30	set	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	c	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	Myb	_	NOUN	_	Number=Sing	_	_	_	_
35	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	targets	_	NOUN	_	Number=Plur	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	such	_	ADJ	_	Degree=Pos	_	_	_	_
39	as	_	ADP	_	_	_	_	_	_
40	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	2	_	NUM	_	NumType=Card	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	CD13	_	PROPN	_	Number=Sing	_	_	_	_
45	/	_	PUNCT	_	_	_	_	_	_
46	APN	_	PROPN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	with	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	activation	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	as	_	ADP	_	_	_	_	_	_
54	yet	_	ADV	_	_	_	_	_	_
55	undefined	_	ADJ	_	Degree=Pos	_	_	_	_
56	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
59	genes	_	NOUN	_	Number=Plur	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011114	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	phagocytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Phagocytosis	_	PROPN	_	Number=Sing	_	_	_	_
2	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	important	_	ADJ	_	Degree=Pos	_	_	_	_
5	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
6	trigger	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	several	_	ADJ	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	DNA	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	primarily	_	ADV	_	_	_	_	_	_
12	consisting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	classical	_	ADJ	_	Degree=Pos	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	p50	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	RelA	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	phagocytosing	_	ADJ	_	VerbForm=Ger	_	_	_	_
30	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Under	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	conditions	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	transient	_	ADJ	_	Degree=Pos	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	reaching	_	VERB	_	VerbForm=Ger	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	maximum	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	10	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	15	_	NUM	_	NumType=Card	_	_	_	_
27	min	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	returning	_	VERB	_	VerbForm=Ger	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	near	_	ADP	_	_	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	basal	_	ADJ	_	Degree=Pos	_	_	_	_
35	levels	_	NOUN	_	Number=Plur	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	30	_	NUM	_	NumType=Card	_	_	_	_
38	min	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
3	undergoing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	phagocytosis	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	opsonized	_	VERB	_	Degree=Pos	_	_	_	_
8	yeasts	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	onset	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	paralleled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	decline	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	immunoreactive	_	ADJ	_	Degree=Pos	_	_	_	_
25	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
26	kappa	_	VERB	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	protein	_	NOUN	_	Number=Sing	_	_	_	_
31	levels	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	cellular	_	ADJ	_	Number=Sing	_	_	_	_
36	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
37	kappa	_	VERB	_	Number=Sing	_	_	_	_
38	B	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	alpha	_	NOUN	_	Number=Sing	_	_	_	_
41	pool	_	NOUN	_	Number=Sing	_	_	_	_
42	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
43	replenished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	by	_	ADP	_	_	_	_	_	_
45	30	_	NUM	_	NumType=Card	_	_	_	_
46	min	_	NOUN	_	Number=Plur	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	agreement	_	NOUN	_	Number=Sing	_	_	_	_
50	with	_	ADP	_	_	_	_	_	_
51	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
52	gel	_	NOUN	_	Number=Sing	_	_	_	_
53	shift	_	NOUN	_	Number=Sing	_	_	_	_
54	data	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	could	_	AUX	_	VerbForm=Fin	_	_	_	_
10	constitute	_	VERB	_	VerbForm=Inf	_	_	_	_
11	one	_	NUM	_	NumType=Card	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
15	whereby	_	ADV	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	phagocytosing	_	ADJ	_	VerbForm=Ger	_	_	_	_
28	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	To	_	ADP	_	_	_	_	_	_
2	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
3	knowledge	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
6	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
9	demonstration	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	phagocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
13	can	_	AUX	_	VerbForm=Fin	_	_	_	_
14	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	PROPN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011122	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	non-erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	silencer	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	globin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	encoding	_	NOUN	_	VerbForm=Ger	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	clarify	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
6	involved	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
10	control	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	hemoglobin	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	encoding	_	VERB	_	Number=Sing	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
19	studying	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	continuous	_	ADJ	_	Degree=Pos	_	_	_	_
30	culture	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	presence	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	control	_	NOUN	_	Number=Sing	_	_	_	_
11	element	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	properties	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	silencer	_	NOUN	_	Number=Sing	_	_	_	_
18	extending	_	VERB	_	VerbForm=Ger	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	-	_	SYM	_	_	_	_	_	_
21	392	_	NUM	_	NumType=Card	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	177	_	NUM	_	NumType=Card	_	_	_	_
25	bp	_	NOUN	_	Number=Sing	_	_	_	_
26	relative	_	ADV	_	_	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	cap	_	NOUN	_	Number=Sing	_	_	_	_
30	site	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	human	_	ADJ	_	Degree=Pos	_	_	_	_
34	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	globin	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	encoding	_	NOUN	_	VerbForm=Ger	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	[	_	PUNCT	_	_	_	_	_	_
41	Cao	_	PROPN	_	Number=Sing	_	_	_	_
42	et	_	X	_	_	_	_	_	_
43	al	_	PROPN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_

1	Proc.Natl.Acad.Sci.USA	_	PROPN	_	Number=Sing	_	_	_	_
2	86	_	NUM	_	NumType=Card	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	1989	_	NUM	_	NumType=Card	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	5306-5309	_	NUM	_	NumType=Card	_	_	_	_
7	]	_	PUNCT	_	_	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	silencer	_	NOUN	_	Number=Sing	_	_	_	_
7	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	stronger	_	ADJ	_	Degree=Cmp	_	_	_	_
9	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	as	_	SCONJ	_	_	_	_	_	_
16	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	K562	_	NUM	_	NumType=Card	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	erythroleukemia	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	deletion	_	NOUN	_	Number=Sing	_	_	_	_
3	mutants	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	cis	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
9	oligodeoxyribonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	transient	_	ADJ	_	Degree=Pos	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	assays	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
16	sequences	_	NOUN	_	Number=Plur	_	_	_	_
17	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	effect	_	NOUN	_	Number=Sing	_	_	_	_
21	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	now	_	ADV	_	_	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	further	_	ADV	_	_	_	_	_	_
25	delimited	_	ADJ	_	Degree=Pos	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	44	_	NUM	_	NumType=Card	_	_	_	_
28	bp	_	PROPN	_	Number=Sing	_	_	_	_
29	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	-	_	SYM	_	_	_	_	_	_
32	294	_	NUM	_	NumType=Card	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	-	_	SYM	_	_	_	_	_	_
35	251	_	NUM	_	NumType=Card	_	_	_	_
36	bp	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	electrophoresis	_	NOUN	_	Number=Sing	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	DNaseI	_	PROPN	_	Number=Sing	_	_	_	_
8	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
9	assays	_	NOUN	_	Number=Plur	_	_	_	_
10	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	negative	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	sequences	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	differently	_	ADV	_	_	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	proteins	_	NOUN	_	Number=Plur	_	_	_	_
21	present	_	NOUN	_	Degree=Pos	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	extracts	_	NOUN	_	Number=Plur	_	_	_	_
25	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	K562	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	K562	_	NUM	_	Number=Sing	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	extracts	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	while	_	SCONJ	_	_	_	_	_	_
12	only	_	ADV	_	_	_	_	_	_
13	one	_	NUM	_	NumType=Card	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	extracts	_	NOUN	_	Number=Plur	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Possible	_	ADJ	_	Degree=Pos	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	proteins	_	NOUN	_	Number=Plur	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	globin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	encoding	_	NOUN	_	VerbForm=Ger	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	non-erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011124	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
2	cloning	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	NGFI	_	NOUN	_	Number=Sing	_	_	_	_
6	-B	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	nur77-related	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	line	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	line	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	PEER	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	dies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	presence	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	PMA	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	calcium	_	NOUN	_	Number=Sing	_	_	_	_
20	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	new	_	ADJ	_	Degree=Pos	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	TINUR	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
11	PEER	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	TINUR	_	PROPN	_	Degree=Pos	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	within	_	ADP	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	h	_	NOUN	_	Number=Sing	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	cross	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	linking	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	Ag	_	PROPN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	TINUR	_	PROPN	_	Number=Sing	_	_	_	_
2	belongs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	NGFI	_	PROPN	_	Number=Sing	_	_	_	_
6	-B	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	nur77	_	NOUN	_	Number=Sing	_	_	_	_
9	family	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	steroid	_	NOUN	_	Number=Sing	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	orphan	_	ADJ	_	Degree=Pos	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	TINUR	_	ADJ	_	Number=Sing	_	_	_	_
2	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	same	_	ADJ	_	Degree=Pos	_	_	_	_
6	DNA	_	NOUN	_	Number=Sing	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	NGFI-B	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	nur77	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	NGFI	_	PROPN	_	Number=Sing	_	_	_	_
7	-B	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	nur77	_	NOUN	_	Number=Sing	_	_	_	_
10	family	_	NOUN	_	Number=Sing	_	_	_	_
11	can	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	classified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	into	_	ADP	_	_	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	subtypes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011128	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	NF	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
12	lineage	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	invoked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	important	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	cytokine	_	ADJ	_	Degree=Pos	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	surface	_	NOUN	_	Number=Sing	_	_	_	_
30	receptors	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	human	_	ADJ	_	Degree=Pos	_	_	_	_
37	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
38	virus	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	such	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	can	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	without	_	ADP	_	_	_	_	_	_
17	intentional	_	ADJ	_	Degree=Pos	_	_	_	_
18	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	Mono	_	PROPN	_	Number=Sing	_	_	_	_
12	Mac	_	PROPN	_	Number=Sing	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	medium	_	NOUN	_	Number=Sing	_	_	_	_
18	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	fetal	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	calf	_	NOUN	_	Number=Sing	_	_	_	_
22	serum	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	low	_	ADJ	_	Degree=Pos	_	_	_	_
25	levels	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	LPS	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	also	_	ADV	_	_	_	_	_	_
33	exhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
34	such	_	ADJ	_	Degree=Pos	_	_	_	_
35	'	_	PUNCT	_	_	_	_	_	_
36	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
37	'	_	PUNCT	_	_	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	kappa	_	NOUN	_	Number=Sing	_	_	_	_
41	B	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	as	_	SCONJ	_	_	_	_	_	_
44	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	by	_	ADP	_	_	_	_	_	_
46	mobility	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	shift	_	NOUN	_	Number=Sing	_	_	_	_
49	analysis	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
52	extracts	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	still	_	ADV	_	_	_	_	_	_
9	present	_	ADJ	_	Degree=Pos	_	_	_	_
10	when	_	ADV	_	PronType=Int	_	_	_	_
11	contaminant	_	PROPN	_	Number=Sing	_	_	_	_
12	LPS	_	PROPN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	removed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	ultrafiltration	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	when	_	ADV	_	PronType=Int	_	_	_	_
19	serum	_	NOUN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	omitted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	complexes	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
7	NF	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	Number=Sing	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	similar	_	ADJ	_	Degree=Pos	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	mobility	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	LPS	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	both	_	DET	_	_	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	antibody	_	NOUN	_	Number=Sing	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	p50	_	NUM	_	Number=Sing	_	_	_	_
26	subunit	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B.	_	PROPN	_	Number=Sing	_	_	_	_
32	By	_	ADP	_	_	_	_	_	_
33	contrast	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	treatment	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	pyrrolidine	_	NOUN	_	Number=Sing	_	_	_	_
40	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	PDTC	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	will	_	AUX	_	VerbForm=Fin	_	_	_	_
45	only	_	ADV	_	_	_	_	_	_
46	block	_	VERB	_	VerbForm=Inf	_	_	_	_
47	LPS	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	NF	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	kappa	_	NOUN	_	Number=Sing	_	_	_	_
53	B	_	NOUN	_	Number=Sing	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	but	_	CCONJ	_	_	_	_	_	_
56	not	_	ADV	_	_	_	_	_	_
57	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
58	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
59	binding	_	NOUN	_	Number=Sing	_	_	_	_
60	protein	_	NOUN	_	Number=Sing	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	LPS	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	free	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	serum	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	free	_	ADJ	_	Degree=Pos	_	_	_	_
9	conditions	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	can	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	different	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	lines	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
26	lineage	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	HL60	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	U937	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	THP	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	Mono	_	PROPN	_	Number=Sing	_	_	_	_
37	Mac	_	PROPN	_	Number=Sing	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	Mono	_	PROPN	_	Number=Sing	_	_	_	_
41	Mac	_	PROPN	_	Number=Sing	_	_	_	_
42	6	_	NUM	_	NumType=Card	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	but	_	CCONJ	_	_	_	_	_	_
46	not	_	ADV	_	_	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	Molt	_	NOUN	_	Number=Sing	_	_	_	_
49	4	_	NUM	_	NumType=Card	_	_	_	_
50	T	_	NOUN	_	Number=Sing	_	_	_	_
51	cells	_	NOUN	_	Number=Plur	_	_	_	_
52	or	_	CCONJ	_	_	_	_	_	_
53	K562	_	NUM	_	NumType=Card	_	_	_	_
54	stem	_	NOUN	_	Number=Sing	_	_	_	_
55	cells	_	NOUN	_	Number=Plur	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	ordered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	according	_	VERB	_	VerbForm=Ger	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	stage	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	maturation	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	amount	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
13	NF	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	more	_	ADJ	_	Degree=Cmp	_	_	_	_
22	mature	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	lines	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	when	_	ADV	_	PronType=Int	_	_	_	_
4	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	Mono	_	PROPN	_	Number=Sing	_	_	_	_
8	Mac	_	PROPN	_	Number=Sing	_	_	_	_
9	6	_	NUM	_	NumType=Card	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
14	D3	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	no	_	DET	_	_	_	_	_	_
17	change	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	constitutive	_	ADJ	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	can	_	AUX	_	VerbForm=Fin	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	primary	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
7	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
8	NF	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	blood	_	NOUN	_	Number=Sing	_	_	_	_
17	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	pleural	_	ADJ	_	Degree=Pos	_	_	_	_
20	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
23	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	functionally	_	ADV	_	_	_	_	_	_
11	active	_	ADJ	_	Degree=Pos	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	since	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	low	_	ADJ	_	Degree=Pos	_	_	_	_
16	level	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	tumour	_	NOUN	_	Number=Sing	_	_	_	_
19	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	TNF	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	transcript	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
32	level	_	NOUN	_	Number=Sing	_	_	_	_
33	can	_	AUX	_	VerbForm=Fin	_	_	_	_
34	be	_	AUX	_	VerbForm=Inf	_	_	_	_
35	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	blocking	_	NOUN	_	VerbForm=Ger	_	_	_	_
38	transcript	_	NOUN	_	Number=Sing	_	_	_	_
39	degradation	_	NOUN	_	Number=Sing	_	_	_	_
40	using	_	VERB	_	VerbForm=Ger	_	_	_	_
41	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	level	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	variable	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	frequently	_	ADV	_	_	_	_	_	_
17	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	more	_	ADV	_	_	_	_	_	_
24	mature	_	ADJ	_	Degree=Pos	_	_	_	_
25	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	maintained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	autocrine	_	ADJ	_	Degree=Pos	_	_	_	_
7	action	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
10	TNF	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
16	10	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
21	colony	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
27	colony	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	since	_	SCONJ	_	_	_	_	_	_
33	neutralizing	_	VERB	_	VerbForm=Ger	_	_	_	_
34	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
35	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	not	_	PART	_	_	_	_	_	_
37	reduce	_	VERB	_	VerbForm=Inf	_	_	_	_
38	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
39	DNA	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	binding	_	NOUN	_	Number=Sing	_	_	_	_
42	activity	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	blockade	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	prostaglandin	_	PROPN	_	Number=Sing	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	leukotriene	_	NOUN	_	Number=Sing	_	_	_	_
8	biosynthesis	_	NOUN	_	Number=Sing	_	_	_	_
9	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
12	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B.	_	PROPN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	ABSTRACT	_	PROPN	_	Number=Sing	_	_	_	_
19	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	AT	_	ADP	_	_	_	_	_	_
21	400	_	NUM	_	NumType=Card	_	_	_	_
22	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	Document	_	NOUN	_	Number=Sing	_	_	_	_
25	0030011130	_	NUM	_	NumType=Card	_	_	_	_
26	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	NOUN	_	Number=Sing	_	_	_	_
3	anergized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	CD4	_	NOUN	_	Number=Sing	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	express	_	VERB	_	Degree=Pos	_	_	_	_
4	perturbed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	AP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Anergy	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	major	_	ADJ	_	Degree=Pos	_	_	_	_
5	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	ensure	_	VERB	_	VerbForm=Inf	_	_	_	_
8	antigen	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	adult	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	anergy	_	NOUN	_	Number=Sing	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	mainly	_	ADV	_	_	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
12	level	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	superantigen	_	NOUN	_	Number=Sing	_	_	_	_
12	staphylococcal	_	ADJ	_	Degree=Pos	_	_	_	_
13	enterotoxin	_	NOUN	_	Number=Sing	_	_	_	_
14	A	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	SEA	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
21	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	T-lymphocyte	_	ADJ	_	Number=Sing	_	_	_	_
24	anergy	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vivo	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Injection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	SEA	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	adult	_	NOUN	_	VerbForm=Inf	_	_	_	_
6	mice	_	NOUN	_	Number=Plur	_	_	_	_
7	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	CD4	_	PROPN	_	Number=Sing	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	certain	_	ADJ	_	Degree=Pos	_	_	_	_
5	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	TCR	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	variable	_	ADJ	_	Degree=Pos	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	beta-chain	_	NOUN	_	Number=Sing	_	_	_	_
13	families	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	induces	_	VERB	_	Number=Plur	_	_	_	_
16	strong	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
19	production	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	repeated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	injections	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	SEA	_	NOUN	_	Number=Sing	_	_	_	_
8	cause	_	NOUN	_	Number=Sing	_	_	_	_
9	CD4	_	PROPN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_

1	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
2	deletion	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	anergy	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	remaining	_	ADJ	_	Degree=Pos	_	_	_	_
8	CD4	_	NOUN	_	Number=Sing	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_

1	T	_	X	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	levels	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	AP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	AT	_	ADP	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	octamer	_	NOUN	_	Number=Sing	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	be	_	AUX	_	VerbForm=Inf	_	_	_	_
29	involved	_	ADJ	_	Degree=Pos	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	regulation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	gene	_	NOUN	_	Number=Sing	_	_	_	_
38	promoter	_	NOUN	_	Number=Sing	_	_	_	_
39	activity	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Large	_	ADJ	_	Degree=Pos	_	_	_	_
2	amounts	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	NF	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	significant	_	ADJ	_	Degree=Pos	_	_	_	_
14	quantities	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	AT	_	NOUN	_	Number=Sing	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	SEA	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	CD4	_	NOUN	_	Number=Sing	_	_	_	_
26	+	_	SYM	_	_	_	_	_	_
27	spleen	_	NOUN	_	Number=Sing	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	whereas	_	SCONJ	_	_	_	_	_	_
32	Oct	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	Oct	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	DNA	_	NOUN	_	Number=Sing	_	_	_	_
40	binding	_	NOUN	_	Number=Sing	_	_	_	_
41	activity	_	NOUN	_	Number=Sing	_	_	_	_
42	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
43	similar	_	ADJ	_	Degree=Pos	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	both	_	CCONJ	_	_	_	_	_	_
46	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	T	_	NOUN	_	Number=Sing	_	_	_	_
50	cells	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	anergic	_	PROPN	_	Degree=Pos	_	_	_	_
5	CD4	_	PROPN	_	Number=Sing	_	_	_	_
6	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	severely	_	ADV	_	_	_	_	_	_
5	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	AP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	SYM	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Fos	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	Jun	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	AT	_	ADP	_	_	_	_	_	_
20	complexes	_	NOUN	_	Number=Plur	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	significant	_	ADJ	_	Degree=Pos	_	_	_	_
24	amounts	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	Oct	_	PROPN	_	Number=Sing	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	proteins	_	NOUN	_	Number=Plur	_	_	_	_
34	after	_	ADP	_	_	_	_	_	_
35	SEA	_	NOUN	_	Number=Sing	_	_	_	_
36	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Resolution	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	complex	_	NOUN	_	Number=Sing	_	_	_	_
9	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	predominant	_	ADJ	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	p50-p65	_	NUM	_	NumType=Card	_	_	_	_
14	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	CD4	_	PROPN	_	Number=Sing	_	_	_	_
18	+	_	SYM	_	_	_	_	_	_

1	T	_	X	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	while	_	SCONJ	_	_	_	_	_	_
5	anergic	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	mainly	_	ADV	_	_	_	_	_	_
8	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcriptionally	_	ADV	_	_	_	_	_	_
11	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
12	p50	_	NOUN	_	Number=Sing	_	_	_	_
13	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	alterations	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	likely	_	ADV	_	Degree=Pos	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	repression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	anergic	_	ADJ	_	Degree=Pos	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011132	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	SP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	preferential	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	keratinocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1beta	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1beta	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	non-monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
22	constructed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	series	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	reporter	_	NOUN	_	Number=Sing	_	_	_	_
27	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
31	chloramphenicol	_	NOUN	_	Number=Sing	_	_	_	_
32	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	various	_	ADJ	_	Degree=Pos	_	_	_	_
37	parts	_	NOUN	_	Number=Plur	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	human	_	ADJ	_	Degree=Pos	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	1beta	_	PROPN	_	Number=Sing	_	_	_	_
44	promoter	_	NOUN	_	Number=Sing	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	performed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	transient	_	ADJ	_	Degree=Pos	_	_	_	_
48	transfection	_	NOUN	_	Number=Sing	_	_	_	_
49	experiments	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	segment	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	most	_	ADV	_	_	_	_	_	_
10	efficiently	_	ADV	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	keratinocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	43	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	mer	_	NOUN	_	Number=Sing	_	_	_	_
13	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
14	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	functionally	_	ADV	_	_	_	_	_	_
18	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cis	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	element	_	NOUN	_	Number=Sing	_	_	_	_
23	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	complexes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	competition	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	consensus	_	NOUN	_	Number=Sing	_	_	_	_
8	sequence	_	NOUN	_	Number=Sing	_	_	_	_
9	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	immunosupershift	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	SP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	closely	_	ADV	_	_	_	_	_	_
22	related	_	ADJ	_	Degree=Pos	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	element	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	closest	_	ADJ	_	Degree=Sup	_	_	_	_
3	match	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	SP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	consensus	_	NOUN	_	Number=Sing	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	within	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	respective	_	ADJ	_	Degree=Pos	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	TCCCCTCCCCT	_	PROPN	_	Number=Sing	_	_	_	_
19	motif	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	motif	_	NOUN	_	Number=Sing	_	_	_	_
5	almost	_	ADV	_	_	_	_	_	_
6	completely	_	ADV	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	specifically	_	ADV	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	abolished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	low	_	ADJ	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	mobility	_	NOUN	_	Number=Sing	_	_	_	_
19	complexes	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	95	_	NUM	_	NumType=Card	_	_	_	_
25	%	_	SYM	_	Number=Sing	_	_	_	_
26	decrease	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
29	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	reporter	_	NOUN	_	Number=Sing	_	_	_	_
34	construct	_	VERB	_	Number=Sing	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1beta	_	PROPN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	-	_	SYM	_	_	_	_	_	_
40	170/+108	_	NUM	_	NumType=Card	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Likewise	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	reporter	_	NOUN	_	Number=Sing	_	_	_	_
7	construct	_	VERB	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	depended	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	SP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	so	_	ADV	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	far	_	ADV	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	unrecognized	_	ADJ	_	Degree=Pos	_	_	_	_
11	SP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1beta	_	PROPN	_	Number=Sing	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	may	_	AUX	_	VerbForm=Fin	_	_	_	_
23	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
27	regulation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	keratinocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011133	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Multifactor	_	NOUN	_	Number=Sing	_	_	_	_
2	cis-dominant	_	NOUN	_	Degree=Pos	_	_	_	_
3	negative	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	anergized	_	VERB	_	Degree=Pos	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
4	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	blockade	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	anergic	_	ADJ	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	clones	_	NOUN	_	Number=Plur	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	fully	_	ADV	_	_	_	_	_	_
18	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	active	_	ADJ	_	Degree=Pos	_	_	_	_
6	negative	_	ADJ	_	Degree=Pos	_	_	_	_
7	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	process	_	NOUN	_	Number=Sing	_	_	_	_
9	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	created	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	reporter	_	NOUN	_	Number=Sing	_	_	_	_
15	construct	_	NOUN	_	Number=Sing	_	_	_	_
16	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
20	four	_	NUM	_	NumType=Card	_	_	_	_
21	copies	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	AT	_	ADP	_	_	_	_	_	_
27	site	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	one	_	NUM	_	NumType=Card	_	_	_	_
30	copy	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	octamer	_	NOUN	_	Number=Sing	_	_	_	_
34	site	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	4X	_	NUM	_	NumType=Card	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	AT	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	Oct	_	PROPN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	construct	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	only	_	ADV	_	_	_	_	_	_
5	slightly	_	ADV	_	_	_	_	_	_
6	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	1.3	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	fold	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	when	_	ADV	_	PronType=Int	_	_	_	_
16	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	under	_	ADP	_	_	_	_	_	_
18	anergic	_	ADJ	_	Degree=Pos	_	_	_	_
19	conditions	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	while	_	SCONJ	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	whole	_	ADJ	_	Degree=Pos	_	_	_	_
24	mouse	_	NOUN	_	Number=Sing	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
29	construct	_	NOUN	_	Number=Sing	_	_	_	_
30	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	reduction	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	4.3-	_	NUM	_	NumType=Card	_	_	_	_
35	fold	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Addition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	176	_	NUM	_	NumType=Card	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	96	_	NUM	_	NumType=Card	_	_	_	_
9	sequence	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	4X	_	PROPN	_	NumType=Card	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	AT	_	ADP	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	Oct	_	PROPN	_	Number=Sing	_	_	_	_
18	construct	_	NOUN	_	Number=Sing	_	_	_	_
19	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	impart	_	VERB	_	VerbForm=Inf	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	ability	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	anergy	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	but	_	CCONJ	_	_	_	_	_	_
31	addition	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	236	_	NUM	_	NumType=Card	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	-	_	SYM	_	_	_	_	_	_
38	96	_	NUM	_	NumType=Card	_	_	_	_
39	sequence	_	NOUN	_	Number=Sing	_	_	_	_
40	did	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
43	that	_	SCONJ	_	_	_	_	_	_
44	anergy	_	NOUN	_	Number=Sing	_	_	_	_
45	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
46	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
47	active	_	ADJ	_	Degree=Pos	_	_	_	_
48	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
49	process	_	NOUN	_	Number=Sing	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	that	_	ADV	_	_	_	_	_	_
52	more	_	ADJ	_	Degree=Cmp	_	_	_	_
53	than	_	ADP	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	presence	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	150	_	NUM	_	NumType=Card	_	_	_	_
60	AP	_	NOUN	_	Number=Sing	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	1	_	NUM	_	NumType=Card	_	_	_	_
63	binding	_	NOUN	_	Number=Sing	_	_	_	_
64	site	_	NOUN	_	Number=Sing	_	_	_	_
65	(	_	PUNCT	_	_	_	_	_	_
66	-	_	SYM	_	_	_	_	_	_
67	152	_	NUM	_	NumType=Card	_	_	_	_
68	to	_	ADP	_	_	_	_	_	_
69	-	_	SYM	_	_	_	_	_	_
70	147	_	NUM	_	NumType=Card	_	_	_	_
71	)	_	PUNCT	_	_	_	_	_	_
72	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
73	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
74	to	_	PART	_	_	_	_	_	_
75	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
76	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
77	effect	_	NOUN	_	Number=Sing	_	_	_	_
78	.	_	PUNCT	_	_	_	_	_	_

1	Mutational	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	236	_	NUM	_	NumType=Card	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	-	_	SYM	_	_	_	_	_	_
9	96	_	NUM	_	NumType=Card	_	_	_	_
10	sequence	_	NOUN	_	Number=Sing	_	_	_	_
11	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	presence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	both	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	130	_	NUM	_	NumType=Card	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	like	_	ADJ	_	Degree=Pos	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	-	_	SYM	_	_	_	_	_	_
28	187	_	NUM	_	NumType=Card	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	-	_	SYM	_	_	_	_	_	_
31	181	_	NUM	_	NumType=Card	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	150	_	NUM	_	NumType=Card	_	_	_	_
37	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
38	AP	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	site	_	NOUN	_	Number=Sing	_	_	_	_
42	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
44	to	_	PART	_	_	_	_	_	_
45	observe	_	VERB	_	VerbForm=Inf	_	_	_	_
46	anergy	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	180	_	NUM	_	NumType=Card	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	trans	_	NOUN	_	Number=Plur	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	possible	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	confirm	_	VERB	_	VerbForm=Inf	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	mutation	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	normal	_	ADJ	_	Degree=Pos	_	_	_	_
24	mouse	_	NOUN	_	Number=Sing	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
29	that	_	PRON	_	_	_	_	_	_
30	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	absolutely	_	ADV	_	_	_	_	_	_
34	essential	_	ADJ	_	Degree=Pos	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	anergy	_	NOUN	_	Number=Sing	_	_	_	_
37	induction	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	simplest	_	ADJ	_	Degree=Sup	_	_	_	_
3	model	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	results	_	NOUN	_	Number=Plur	_	_	_	_
8	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	anergy	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	complex	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factors	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	exert	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	cis	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
27	negative	_	ADJ	_	Degree=Pos	_	_	_	_
28	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
29	effect	_	NOUN	_	Number=Sing	_	_	_	_
30	on	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	trans	_	NOUN	_	Number=Plur	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011135	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cytokine	_	VERB	_	Number=Sing	_	_	_	_
2	modulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	Cytokines	_	NOUN	_	Number=Plur	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	peptide	_	NOUN	_	Degree=Pos	_	_	_	_
5	hormones	_	NOUN	_	Number=Plur	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	homeostasis	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	immune	_	NOUN	_	Number=Sing	_	_	_	_
13	system	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	play	_	VERB	_	VerbForm=Inf	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	fundamental	_	ADJ	_	Degree=Pos	_	_	_	_
19	role	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	immune	_	ADJ	_	Degree=Pos	_	_	_	_
24	mediated	_	VERB	_	Degree=Pos	_	_	_	_
25	reactions	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
29	involved	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	at	_	ADP	_	_	_	_	_	_
31	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
32	levels	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	acquired	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	immune	_	ADJ	_	Number=Sing	_	_	_	_
40	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
41	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Infection	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HIV	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
15	production	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	several	_	ADJ	_	Degree=Pos	_	_	_	_
18	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	vitro	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	vivo	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Conversely	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	several	_	ADJ	_	Degree=Pos	_	_	_	_
4	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
5	modulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	T	_	ADJ	_	Number=Sing	_	_	_	_
17	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	phagocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	lineage	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	particularly	_	ADV	_	_	_	_	_	_
6	B	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	state	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	individuals	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	release	_	VERB	_	VerbForm=Inf	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	inductive	_	ADJ	_	Degree=Pos	_	_	_	_
25	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	thus	_	ADV	_	_	_	_	_	_
28	play	_	VERB	_	VerbForm=Inf	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	potentially	_	ADV	_	_	_	_	_	_
31	important	_	ADJ	_	Degree=Pos	_	_	_	_
32	role	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	HIV	_	NOUN	_	Number=Sing	_	_	_	_
38	infection	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011140	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
5	upstream	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	GATA	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	GATA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	subset	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	hemopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	where	_	ADV	_	PronType=Rel	_	_	_	_
17	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
18	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	several	_	ADJ	_	Degree=Pos	_	_	_	_
27	genes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	mouse	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	GATA	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	upstream	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	exon	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	highly	_	ADV	_	_	_	_	_	_
11	conserved	_	VERB	_	Degree=Pos	_	_	_	_
12	between	_	ADP	_	_	_	_	_	_
13	mouse	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	man	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
21	specific	_	ADJ	_	Degree=Pos	_	_	_	_
22	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	transient	_	ADJ	_	Number=Sing	_	_	_	_
25	assays	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	if	_	SCONJ	_	_	_	_	_	_
28	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	GATA	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	SV40	_	NOUN	_	Number=Sing	_	_	_	_
38	promoter	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	almost	_	ADV	_	_	_	_	_	_
8	completely	_	ADV	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	integrity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	dimeric	_	ADJ	_	Degree=Pos	_	_	_	_
16	GATA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011145	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	interferon	_	NOUN	_	Number=Sing	_	_	_	_
6	isotypes	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
9	blood	_	NOUN	_	Number=Sing	_	_	_	_
10	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	normal	_	ADJ	_	Degree=Pos	_	_	_	_
13	individuals	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
17	U937	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IFN	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha5	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	IFN	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	beta	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	different	_	ADJ	_	Degree=Pos	_	_	_	_
15	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	including	_	VERB	_	VerbForm=Ger	_	_	_	_
18	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
19	blood	_	NOUN	_	Number=Sing	_	_	_	_
20	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	normal	_	ADJ	_	Degree=Pos	_	_	_	_
24	individuals	_	NOUN	_	Number=Plur	_	_	_	_
25	following	_	VERB	_	VerbForm=Ger	_	_	_	_
26	amplification	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	IFN	_	PROPN	_	Number=Sing	_	_	_	_
29	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	reverse	_	NOUN	_	Number=Sing	_	_	_	_
32	transcriptase	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
35	chain	_	NOUN	_	Number=Sing	_	_	_	_
36	reaction	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	direct	_	ADJ	_	Degree=Pos	_	_	_	_
39	sequencing	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	amplified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	product	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	form	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	interferon	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	complex	_	NOUN	_	Number=Sing	_	_	_	_
12	ISGF3	_	PROPN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	extracts	_	NOUN	_	Number=Plur	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	uninduced	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Culture	_	NOUN	_	Number=Sing	_	_	_	_
2	supernatants	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	uninduced	_	ADJ	_	Degree=Pos	_	_	_	_
5	U937	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	ISRE	_	PROPN	_	Number=Sing	_	_	_	_
14	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	upstream	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	luciferase	_	ADJ	_	Number=Sing	_	_	_	_
19	reporter	_	NOUN	_	Number=Sing	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	presence	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
27	IFN	_	PROPN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	equivalent	_	ADJ	_	Degree=Pos	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	approximately	_	ADV	_	_	_	_	_	_
32	0.3	_	NUM	_	NumType=Card	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	0.5	_	NUM	_	NumType=Card	_	_	_	_
35	IU	_	NUM	_	Number=Sing	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	mL	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
3	IFN	_	PROPN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	play	_	VERB	_	VerbForm=Inf	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	SCONJ	_	_	_	_	_	_
12	maintaining	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	basal	_	ADJ	_	Degree=Pos	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	major	_	ADJ	_	Degree=Pos	_	_	_	_
21	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
22	class	_	NOUN	_	Number=Sing	_	_	_	_
23	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
24	genes	_	VERB	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alpha5	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	IFN	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	low	_	ADJ	_	Degree=Pos	_	_	_	_
16	levels	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	tissues	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	play	_	VERB	_	VerbForm=Inf	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	important	_	ADJ	_	Degree=Pos	_	_	_	_
24	role	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	regulation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	function	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	maintenance	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	homeostasis	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011149	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kB	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kB	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	eukaryotic	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	lines	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kB	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	bound	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
17	proteic	_	ADJ	_	Number=Sing	_	_	_	_
18	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IkB	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
9	esters	_	NOUN	_	Number=Plur	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kB	_	NOUN	_	Number=Sing	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	translocation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kB	_	NOUN	_	Number=Sing	_	_	_	_
31	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	genes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kB	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
15	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	differences	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
7	+	_	SYM	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	i	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	requirement	_	VERB	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kB	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	as	_	SCONJ	_	_	_	_	_	_
19	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	mature	_	ADJ	_	Degree=Pos	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	constitutively	_	ADV	_	_	_	_	_	_
11	active	_	ADJ	_	Degree=Pos	_	_	_	_
12	form	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kB	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	vivo	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011151	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Requirements	_	NOUN	_	Number=Plur	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
6	D	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	normal	_	ADJ	_	Degree=Pos	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Mature	_	ADJ	_	Degree=Pos	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	unique	_	ADJ	_	Degree=Pos	_	_	_	_
6	targets	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	alpha,25	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
12	D3	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	25	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	OH	_	INTJ	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	2D3	_	NUM	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
26	D	_	PROPN	_	Number=Sing	_	_	_	_
27	receptors	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	VDR	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	not	_	PART	_	_	_	_	_	_
33	constitutively	_	ADV	_	_	_	_	_	_
34	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	specific	_	ADJ	_	Degree=Pos	_	_	_	_
38	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	signals	_	NOUN	_	Number=Plur	_	_	_	_
41	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
42	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	for	_	ADP	_	_	_	_	_	_
44	both	_	CCONJ	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	up	_	ADP	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	regulation	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	VDR	_	NOUN	_	Number=Sing	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	establishment	_	NOUN	_	Number=Sing	_	_	_	_
53	of	_	ADP	_	_	_	_	_	_
54	reactivity	_	NOUN	_	Number=Sing	_	_	_	_
55	to	_	ADP	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	lipophilic	_	ADJ	_	Degree=Pos	_	_	_	_
58	ligand	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	absence	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	prior	_	ADJ	_	Degree=Pos	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	weak	_	ADJ	_	Degree=Pos	_	_	_	_
27	up	_	ADP	_	_	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	regulation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	VDR	_	PROPN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	but	_	CCONJ	_	_	_	_	_	_
34	fails	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	generate	_	VERB	_	VerbForm=Inf	_	_	_	_
37	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
38	D	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
41	element	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	VDRE	_	X	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
47	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
48	protein	_	NOUN	_	Number=Sing	_	_	_	_
49	complexes	_	NOUN	_	Number=Plur	_	_	_	_
50	or	_	CCONJ	_	_	_	_	_	_
51	to	_	PART	_	_	_	_	_	_
52	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
55	transcription	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	25	_	NUM	_	NumType=Card	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	hydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
60	D3	_	NOUN	_	Number=Sing	_	_	_	_
61	24	_	NUM	_	NumType=Card	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	hydroxylase	_	NOUN	_	Number=Sing	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	either	_	CCONJ	_	_	_	_	_	_
7	ligation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	CD40	_	NOUN	_	Number=Sing	_	_	_	_

1	Ag	_	PROPN	_	Number=Sing	_	_	_	_
2	or	_	CCONJ	_	_	_	_	_	_
3	cross	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Ig	_	PROPN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	also	_	ADV	_	_	_	_	_	_
11	insufficient	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	render	_	VERB	_	VerbForm=Inf	_	_	_	_
14	B	_	ADJ	_	Degree=Pos	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	25	_	NUM	_	NumType=Card	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	OH	_	INTJ	_	_	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	2D3	_	NUM	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
5	lack	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	secosterol	_	NOUN	_	Number=Sing	_	_	_	_
11	can	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	overcome	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	combination	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
24	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	signals	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	G1	_	PROPN	_	Number=Sing	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	cycle	_	NOUN	_	Number=Sing	_	_	_	_
37	progression	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	presence	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	25	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	OH	_	INTJ	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	2D3	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	such	_	DET	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	progression	_	NOUN	_	Number=Sing	_	_	_	_
23	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	up	_	ADP	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	regulation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	VDR	_	NOUN	_	Number=Sing	_	_	_	_
34	message	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	protein	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	establishment	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	VDRE	_	PROPN	_	Number=Sing	_	_	_	_
44	binding	_	NOUN	_	Number=Sing	_	_	_	_
45	complexes	_	NOUN	_	Number=Plur	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	induction	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	24	_	NUM	_	NumType=Card	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	hydroxylase	_	NOUN	_	Number=Sing	_	_	_	_
53	message	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	biologic	_	ADJ	_	Degree=Pos	_	_	_	_
4	functions	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	hormone	_	NOUN	_	Number=Sing	_	_	_	_
12	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	subset	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
5	reactivity	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	25	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	OH	_	INTJ	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	2D3	_	NUM	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	tightly	_	ADV	_	_	_	_	_	_
17	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	B	_	ADJ	_	Number=Sing	_	_	_	_
20	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	requiring	_	VERB	_	VerbForm=Ger	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	signals	_	NOUN	_	Number=Plur	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	initiation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011153	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cis	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	sequences	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	HLA	_	PROPN	_	Number=Sing	_	_	_	_
12	DRA	_	PROPN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	vitro	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	consensus	_	NOUN	_	Number=Sing	_	_	_	_
3	sequences	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	X	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Y	_	NOUN	_	Number=Sing	_	_	_	_
9	boxes	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	capable	_	ADJ	_	Degree=Pos	_	_	_	_
12	of	_	SCONJ	_	_	_	_	_	_
13	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	B	_	ADJ	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	within	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
28	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
29	region	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	major	_	ADJ	_	Degree=Pos	_	_	_	_
32	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
33	complex	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	MHC	_	PROPN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	class	_	NOUN	_	Number=Sing	_	_	_	_
38	II	_	NUM	_	NumType=Card	_	_	_	_
39	promoters	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Unlike	_	ADP	_	_	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	class	_	NOUN	_	Number=Sing	_	_	_	_
4	II	_	NUM	_	Number=Sing	_	_	_	_
5	promoters	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	HLA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	DR	_	PROPN	_	Number=Sing	_	_	_	_
11	alpha	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	DRA	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	also	_	ADV	_	_	_	_	_	_
17	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	one	_	NUM	_	NumType=Card	_	_	_	_
19	element	_	NOUN	_	Number=Sing	_	_	_	_
20	identical	_	ADJ	_	Degree=Pos	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	"	_	PUNCT	_	_	_	_	_	_
24	octamer	_	NOUN	_	Number=Sing	_	_	_	_
25	"	_	PUNCT	_	_	_	_	_	_
26	motif	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
29	variable	_	ADJ	_	Degree=Pos	_	_	_	_
30	region	_	NOUN	_	Number=Sing	_	_	_	_
31	promoters	_	NOUN	_	Number=Plur	_	_	_	_
32	that	_	PRON	_	PronType=Rel	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	B	_	ADJ	_	Degree=Pos	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	specific	_	ADJ	_	Degree=Pos	_	_	_	_
40	transcription	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	"	_	PUNCT	_	_	_	_	_	_
3	octamer	_	NOUN	_	Number=Sing	_	_	_	_
4	"	_	PUNCT	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	context	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	DRA	_	PROPN	_	Number=Sing	_	_	_	_
10	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	capable	_	ADJ	_	Degree=Pos	_	_	_	_
12	of	_	SCONJ	_	_	_	_	_	_
13	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	OTF	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	_	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	OTF	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	_	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	"	_	PUNCT	_	_	_	_	_	_
32	octamer	_	NOUN	_	Number=Sing	_	_	_	_
33	"	_	PUNCT	_	_	_	_	_	_
34	binding	_	VERB	_	Number=Sing	_	_	_	_
35	proteins	_	NOUN	_	Number=Plur	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	but	_	CCONJ	_	_	_	_	_	_
38	at	_	ADV	_	_	_	_	_	_
39	least	_	ADV	_	Degree=Sup	_	_	_	_
40	one	_	NUM	_	NumType=Card	_	_	_	_
41	other	_	ADJ	_	Degree=Pos	_	_	_	_
42	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
43	"	_	PUNCT	_	_	_	_	_	_
44	octamer	_	NOUN	_	Number=Sing	_	_	_	_
45	"	_	PUNCT	_	_	_	_	_	_
46	complex	_	NOUN	_	Number=Sing	_	_	_	_
47	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
48	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	function	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	cis	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	acting	_	VERB	_	Number=Sing	_	_	_	_
11	elements	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	developed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	vitro	_	NOUN	_	Number=Sing	_	_	_	_
19	system	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	DRA	_	NOUN	_	Number=Sing	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	construct	_	NOUN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	more	_	ADV	_	_	_	_	_	_
29	efficiently	_	ADV	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	extracts	_	NOUN	_	Number=Plur	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	B	_	ADJ	_	Degree=Pos	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	than	_	ADP	_	_	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	extracts	_	NOUN	_	Number=Plur	_	_	_	_
38	from	_	ADP	_	_	_	_	_	_
39	class	_	NOUN	_	Number=Sing	_	_	_	_
40	II	_	NUM	_	NumType=Card	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	negative	_	ADJ	_	Degree=Pos	_	_	_	_
43	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	5	_	NUM	_	NumType=Card	_	_	_	_
2	'	_	PUNCT	_	_	_	_	_	_
3	deletion	_	NOUN	_	Number=Sing	_	_	_	_
4	constructs	_	NOUN	_	Number=Plur	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	lacked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	Y	_	NOUN	_	Number=Sing	_	_	_	_
9	box	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	retained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	"	_	PUNCT	_	_	_	_	_	_
15	octamer	_	NOUN	_	Number=Sing	_	_	_	_
16	"	_	PUNCT	_	_	_	_	_	_
17	motif	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	TATA	_	PROPN	_	Number=Sing	_	_	_	_
20	box	_	NOUN	_	Number=Sing	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	completely	_	ADV	_	_	_	_	_	_
23	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	internal	_	ADJ	_	Degree=Pos	_	_	_	_
27	deletion	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	Y	_	NOUN	_	Number=Sing	_	_	_	_
31	box	_	NOUN	_	Number=Sing	_	_	_	_
32	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	95	_	NUM	_	NumType=Card	_	_	_	_
36	%	_	SYM	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	supercoiled	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	but	_	CCONJ	_	_	_	_	_	_
5	not	_	ADV	_	_	_	_	_	_
6	linear	_	ADJ	_	Degree=Pos	_	_	_	_
7	templates	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	differences	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	efficiencies	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	templates	_	NOUN	_	Number=Plur	_	_	_	_
17	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	disrupting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	X	_	SYM	_	_	_	_	_	_
22	consensus	_	NOUN	_	Number=Sing	_	_	_	_
23	element	_	NOUN	_	Number=Sing	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	reflect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	effects	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	random	_	ADJ	_	Degree=Pos	_	_	_	_
29	replacement	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	X	_	NOUN	_	Number=Sing	_	_	_	_
32	box	_	NOUN	_	Number=Sing	_	_	_	_
33	sequences	_	NOUN	_	Number=Plur	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	transient	_	ADJ	_	Degree=Pos	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	assays	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Demonstration	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	complete	_	ADJ	_	Degree=Pos	_	_	_	_
5	dependence	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	Y	_	NOUN	_	Number=Sing	_	_	_	_
9	box	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
12	system	_	NOUN	_	Number=Sing	_	_	_	_
13	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	despite	_	ADP	_	_	_	_	_	_
17	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	importance	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	DRA	_	PROPN	_	Number=Sing	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	DRA	_	PROPN	_	Number=Sing	_	_	_	_
27	"	_	PUNCT	_	_	_	_	_	_
28	octamer	_	NOUN	_	Number=Sing	_	_	_	_
29	"	_	PUNCT	_	_	_	_	_	_
30	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	not	_	PART	_	_	_	_	_	_
32	utilize	_	VERB	_	VerbForm=Inf	_	_	_	_
33	OTF	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	manner	_	NOUN	_	Number=Sing	_	_	_	_
39	analogous	_	ADJ	_	Degree=Pos	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	immunoglobulin	_	VERB	_	Degree=Pos	_	_	_	_
42	promoters	_	NOUN	_	Number=Plur	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	B	_	ADJ	_	Degree=Pos	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011155	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Disruption	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	alpha	_	DET	_	Number=Sing	_	_	_	_
4	beta	_	NOUN	_	Number=Sing	_	_	_	_
5	but	_	CCONJ	_	_	_	_	_	_
6	not	_	ADV	_	_	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	delta	_	PROPN	_	Number=Sing	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	development	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	helix	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	loop	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	helix	_	NOUN	_	Number=Sing	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	Id3	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	committed	_	ADJ	_	Degree=Pos	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Enforced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Id3	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	capacity	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
12	many	_	ADJ	_	Degree=Pos	_	_	_	_
13	basic	_	ADJ	_	Degree=Pos	_	_	_	_
14	helix	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	loop	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	helix	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	bHLH	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	CD34	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	+	_	SYM	_	_	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
32	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	that	_	PRON	_	PronType=Rel	_	_	_	_
35	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	not	_	PART	_	_	_	_	_	_
37	undergone	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	T	_	PROPN	_	Number=Sing	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	receptor	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	TCR	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	gene	_	NOUN	_	Number=Sing	_	_	_	_
45	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
46	inhibits	_	VERB	_	Number=Plur	_	_	_	_
47	development	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	cells	_	NOUN	_	Number=Plur	_	_	_	_
52	into	_	ADP	_	_	_	_	_	_
53	TCRalpha	_	PROPN	_	Number=Sing	_	_	_	_
54	beta	_	NOUN	_	Number=Sing	_	_	_	_
55	and	_	CCONJ	_	_	_	_	_	_
56	gamma	_	NOUN	_	Number=Sing	_	_	_	_
57	delta	_	NOUN	_	Number=Sing	_	_	_	_
58	cells	_	NOUN	_	Number=Plur	_	_	_	_
59	in	_	ADP	_	_	_	_	_	_
60	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
61	fetal	_	ADJ	_	Degree=Pos	_	_	_	_
62	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
63	organ	_	ADJ	_	Degree=Pos	_	_	_	_
64	culture	_	NOUN	_	Number=Sing	_	_	_	_
65	(	_	PUNCT	_	_	_	_	_	_
66	FTOC	_	NOUN	_	Number=Sing	_	_	_	_
67	)	_	PUNCT	_	_	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	document	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Id3	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	TCR	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	pre-T	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	inhibits	_	VERB	_	Number=Plur	_	_	_	_
23	development	_	NOUN	_	Number=Sing	_	_	_	_
24	into	_	ADP	_	_	_	_	_	_
25	TCRalpha	_	PROPN	_	Number=Sing	_	_	_	_
26	beta	_	NOUN	_	Number=Sing	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	not	_	ADV	_	_	_	_	_	_
29	into	_	ADP	_	_	_	_	_	_
30	TCRgamma	_	PROPN	_	Number=Sing	_	_	_	_
31	delta	_	NOUN	_	Number=Sing	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Id3	_	PROPN	_	Number=Sing	_	_	_	_
4	impedes	_	VERB	_	Degree=Pos	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	recombination	_	NOUN	_	Number=Sing	_	_	_	_
8	activating	_	VERB	_	Degree=Pos	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	downregulates	_	VERB	_	Number=Plur	_	_	_	_
12	pre-Talpha	_	ADJ	_	Number=Sing	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	possible	_	ADJ	_	Degree=Pos	_	_	_	_
5	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	Id3	_	PROPN	_	Number=Sing	_	_	_	_
9	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	differentially	_	ADV	_	_	_	_	_	_
12	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
13	development	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	pre-T	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	into	_	ADP	_	_	_	_	_	_
18	TCRalpha	_	PROPN	_	Number=Sing	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	gamma	_	NOUN	_	Number=Sing	_	_	_	_
22	delta	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	DET	_	_	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	surface	_	NOUN	_	Number=Sing	_	_	_	_
7	CD4	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	-)	_	PUNCT	_	_	_	_	_	_
10	CD8	_	NOUN	_	Number=Sing	_	_	_	_
11	(-	_	PUNCT	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	CD3	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	-)	_	PUNCT	_	_	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	rearranged	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
19	TCR	_	NOUN	_	Number=Sing	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	developed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	Id3	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	not	_	ADV	_	_	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	control	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	pre-T	_	ADJ	_	Degree=Pos	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	FTOC	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	properties	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	natural	_	ADJ	_	Degree=Pos	_	_	_	_
8	killer	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	NK	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	pre-T	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	bHLH	_	ADJ	_	Number=Sing	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	control	_	VERB	_	VerbForm=Inf	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	development	_	NOUN	_	Number=Sing	_	_	_	_
14	after	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	T/NK	_	PROPN	_	Number=Sing	_	_	_	_
17	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
18	checkpoint	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011156	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Physical	_	ADJ	_	Degree=Pos	_	_	_	_
2	interactions	_	NOUN	_	Number=Plur	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	Ets	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	play	_	VERB	_	VerbForm=Inf	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	important	_	ADJ	_	Degree=Pos	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	cooperative	_	ADJ	_	Degree=Pos	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
24	virus	_	NOUN	_	Number=Sing	_	_	_	_
25	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	T	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
3	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	elements	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	many	_	ADJ	_	Degree=Pos	_	_	_	_
7	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
8	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	overlapping	_	VERB	_	VerbForm=Ger	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	sites	_	NOUN	_	Number=Plur	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	Ets	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
25	families	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	arrays	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	functionally	_	ADV	_	_	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	NF-kappaB	_	PROPN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	Ets	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	present	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
22	viruses	_	NOUN	_	Number=Plur	_	_	_	_
23	types	_	NOUN	_	Number=Plur	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	HIV	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	HIV	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
38	that	_	SCONJ	_	_	_	_	_	_
39	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
40	pattern	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
43	protein	_	NOUN	_	Number=Sing	_	_	_	_
44	binding	_	NOUN	_	Number=Sing	_	_	_	_
45	sites	_	NOUN	_	Number=Plur	_	_	_	_
46	reflects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
47	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
48	evolutionarily	_	ADV	_	_	_	_	_	_
49	conserved	_	ADJ	_	Degree=Pos	_	_	_	_
50	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
51	for	_	SCONJ	_	_	_	_	_	_
52	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
53	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
54	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
55	gene	_	NOUN	_	Number=Sing	_	_	_	_
56	expression	_	NOUN	_	Number=Sing	_	_	_	_
57	that	_	PRON	_	PronType=Rel	_	_	_	_
58	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
59	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
60	co-opted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
61	during	_	ADP	_	_	_	_	_	_
62	HIV	_	NOUN	_	Number=Sing	_	_	_	_
63	evolution	_	NOUN	_	Number=Sing	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	Despite	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	findings	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	Ets	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	cooperatively	_	ADV	_	_	_	_	_	_
19	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
21	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	report	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	physical	_	ADJ	_	Degree=Pos	_	_	_	_
13	interaction	_	NOUN	_	Number=Sing	_	_	_	_
14	between	_	ADP	_	_	_	_	_	_
15	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
16	Ets	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	both	_	CCONJ	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vitro	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	normal	_	ADJ	_	Degree=Pos	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	interaction	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Ets	_	NOUN	_	Number=Sing	_	_	_	_
8	domain	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Ets	_	NOUN	_	Number=Sing	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	C	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	terminal	_	NOUN	_	Number=Sing	_	_	_	_
17	region	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	Rel	_	PROPN	_	Number=Sing	_	_	_	_
21	homology	_	NOUN	_	Number=Sing	_	_	_	_
22	domains	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
29	proteins	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	Ets-NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
10	interaction	_	NOUN	_	Number=Sing	_	_	_	_
11	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	presence	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	DNA	_	NOUN	_	Number=Sing	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	sites	_	NOUN	_	Number=Plur	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	both	_	DET	_	_	_	_	_	_
20	proteins	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	as	_	SCONJ	_	_	_	_	_	_
23	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	DNA	_	PROPN	_	Number=Sing	_	_	_	_
29	intercalating	_	VERB	_	Number=Sing	_	_	_	_
30	agents	_	NOUN	_	Number=Plur	_	_	_	_
31	propidium	_	ADJ	_	Number=Sing	_	_	_	_
32	iodide	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	ethidium	_	NOUN	_	Number=Sing	_	_	_	_
35	bromide	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	presence	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
43	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
44	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
45	binding	_	NOUN	_	Number=Sing	_	_	_	_
46	sites	_	NOUN	_	Number=Plur	_	_	_	_
47	for	_	ADP	_	_	_	_	_	_
48	Ets	_	NOUN	_	Number=Sing	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	NF	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
53	proteins	_	NOUN	_	Number=Plur	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	negative	_	ADJ	_	Degree=Pos	_	_	_	_
5	mutant	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	p50	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	DNA	_	PROPN	_	Number=Sing	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	fails	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	Ets	_	NOUN	_	Number=Sing	_	_	_	_
20	proteins	_	NOUN	_	Number=Plur	_	_	_	_
21	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	HIV	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	HIV	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	p50	_	NUM	_	Number=Sing	_	_	_	_
41	+	_	SYM	_	_	_	_	_	_
42	p65	_	NUM	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	Ets	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
50	that	_	SCONJ	_	_	_	_	_	_
51	physical	_	ADJ	_	Degree=Pos	_	_	_	_
52	interaction	_	NOUN	_	Number=Sing	_	_	_	_
53	between	_	ADP	_	_	_	_	_	_
54	Ets	_	NOUN	_	Number=Sing	_	_	_	_
55	and	_	CCONJ	_	_	_	_	_	_
56	NF	_	PROPN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
59	proteins	_	NOUN	_	Number=Plur	_	_	_	_
60	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
61	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
62	for	_	ADP	_	_	_	_	_	_
63	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
64	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
65	activity	_	NOUN	_	Number=Sing	_	_	_	_
66	of	_	ADP	_	_	_	_	_	_
67	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
68	HIV	_	NOUN	_	Number=Sing	_	_	_	_
69	-	_	PUNCT	_	_	_	_	_	_
70	1	_	NUM	_	NumType=Card	_	_	_	_
71	and	_	CCONJ	_	_	_	_	_	_
72	HIV	_	NOUN	_	Number=Sing	_	_	_	_
73	-	_	PUNCT	_	_	_	_	_	_
74	2	_	NUM	_	NumType=Card	_	_	_	_
75	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
76	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	findings	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	evolutionarily	_	ADV	_	_	_	_	_	_
9	conserved	_	VERB	_	Degree=Pos	_	_	_	_
10	physical	_	ADJ	_	Degree=Pos	_	_	_	_
11	interactions	_	NOUN	_	Number=Plur	_	_	_	_
12	between	_	ADP	_	_	_	_	_	_
13	Ets	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
20	proteins	_	NOUN	_	Number=Plur	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	important	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	SCONJ	_	_	_	_	_	_
24	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	viruses	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	interactions	_	NOUN	_	Number=Plur	_	_	_	_
3	represent	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	potential	_	ADJ	_	Degree=Pos	_	_	_	_
6	target	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	development	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	novel	_	NOUN	_	Number=Sing	_	_	_	_
12	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	antiviral	_	ADJ	_	Degree=Pos	_	_	_	_
15	therapies	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011158	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	CD3-CD16	_	PROPN	_	Number=Sing	_	_	_	_
3	+	_	SYM	_	_	_	_	_	_
4	natural	_	ADJ	_	Degree=Pos	_	_	_	_
5	killer	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	hGATA	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	T	_	NOUN	_	NumType=Card	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	unrearranged	_	ADJ	_	Degree=Pos	_	_	_	_
19	2.3	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kb	_	NOUN	_	Number=Sing	_	_	_	_
22	TcR	_	PROPN	_	Number=Sing	_	_	_	_
23	delta	_	NOUN	_	Number=Sing	_	_	_	_
24	transcript	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	TcR	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	delta	_	NOUN	_	Number=Sing	_	_	_	_
14	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
15	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	CD3	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	CD16	_	PROPN	_	Number=Sing	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
24	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	whether	_	SCONJ	_	_	_	_	_	_
26	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	hGATA	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	3	_	NUM	_	NumType=Card	_	_	_	_
33	T	_	NOUN	_	NumType=Card	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	factor	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	recombination	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
42	gene	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	RAG	_	NOUN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Multiple	_	ADJ	_	Degree=Pos	_	_	_	_
2	TcR	_	NOUN	_	Number=Sing	_	_	_	_
3	delta	_	NOUN	_	Number=Sing	_	_	_	_
4	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
5	deriving	_	VERB	_	VerbForm=Ger	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	unrearranged	_	ADJ	_	Degree=Pos	_	_	_	_
9	TcR	_	NOUN	_	Number=Sing	_	_	_	_
10	delta	_	NOUN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	clonal	_	ADJ	_	Number=Sing	_	_	_	_
19	CD3	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	CD16	_	PROPN	_	Number=Sing	_	_	_	_
22	+	_	SYM	_	_	_	_	_	_
23	natural	_	ADJ	_	Degree=Pos	_	_	_	_
24	killer	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	NK	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	lines	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	unrearranged	_	ADJ	_	Degree=Pos	_	_	_	_
3	TcR	_	PROPN	_	Number=Sing	_	_	_	_
4	delta	_	NOUN	_	Number=Sing	_	_	_	_
5	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
6	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	size	_	NOUN	_	Number=Sing	_	_	_	_
9	similar	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	functional	_	ADJ	_	Degree=Pos	_	_	_	_
15	TcR	_	PROPN	_	Number=Sing	_	_	_	_
16	delta	_	PROPN	_	Number=Sing	_	_	_	_
17	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	2.3	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	1.3	_	NUM	_	NumType=Card	_	_	_	_
22	kb	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	TcR	_	NOUN	_	Number=Sing	_	_	_	_
27	gamma	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	delta	_	PROPN	_	Number=Sing	_	_	_	_
30	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	Sequence	_	NOUN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	nine	_	NUM	_	NumType=Card	_	_	_	_
5	different	_	ADJ	_	Degree=Pos	_	_	_	_
6	2.3	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kb	_	NOUN	_	Number=Sing	_	_	_	_
9	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
10	clones	_	NOUN	_	Number=Plur	_	_	_	_
11	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	NK	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	polyA	_	NOUN	_	Number=Sing	_	_	_	_
17	+	_	SYM	_	_	_	_	_	_

1	RNA	_	PROPN	_	Number=Sing	_	_	_	_
2	confirmed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
5	corresponded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	unrearranged	_	ADJ	_	Degree=Pos	_	_	_	_
9	TcR	_	NOUN	_	Number=Sing	_	_	_	_
10	delta	_	NOUN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	cDNA	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	2343	_	NUM	_	NumType=Card	_	_	_	_
5	bp	_	PROPN	_	Number=Sing	_	_	_	_
6	long	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	initiation	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	814	_	NUM	_	NumType=Card	_	_	_	_
15	bp	_	NOUN	_	Number=Sing	_	_	_	_
16	upstream	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	J	_	PROPN	_	Number=Sing	_	_	_	_
20	delta	_	PROPN	_	Number=Sing	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	segment	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	upstream	_	ADP	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	J	_	PROPN	_	Number=Sing	_	_	_	_
8	delta	_	PROPN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	segment	_	NOUN	_	Number=Sing	_	_	_	_
11	corresponded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	previously	_	ADV	_	_	_	_	_	_
15	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	germ	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	line	_	NOUN	_	Number=Sing	_	_	_	_
19	sequence	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	J	_	PROPN	_	Number=Sing	_	_	_	_
3	delta	_	PROPN	_	Number=Sing	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	segment	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	correctly	_	ADV	_	_	_	_	_	_
8	spliced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	C	_	PROPN	_	Number=Sing	_	_	_	_
11	delta	_	PROPN	_	Number=Sing	_	_	_	_
12	;	_	PUNCT	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	addition	_	NOUN	_	Number=Sing	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	four	_	NUM	_	NumType=Card	_	_	_	_
17	C	_	PROPN	_	Number=Sing	_	_	_	_
18	delta	_	PROPN	_	Number=Sing	_	_	_	_
19	exons	_	NOUN	_	Number=Plur	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	already	_	ADV	_	_	_	_	_	_
25	assembled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	polyadenylation	_	NOUN	_	Number=Sing	_	_	_	_
3	sites	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	present	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	fourth	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
9	C	_	PROPN	_	Number=Sing	_	_	_	_
10	delta	_	PROPN	_	Number=Sing	_	_	_	_
11	exon	_	PROPN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	only	_	ADV	_	_	_	_	_	_
4	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
5	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	'	_	PUNCT	_	_	_	_	_	_
10	end	_	NOUN	_	Number=Sing	_	_	_	_
11	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	utilized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	2.3	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kb	_	NOUN	_	Number=Sing	_	_	_	_
20	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	hGATA	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	T	_	NUM	_	NumType=Card	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	involved	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	regulation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	TcR	_	PROPN	_	Number=Sing	_	_	_	_
26	delta	_	PROPN	_	Number=Sing	_	_	_	_
27	locus	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
33	blot	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	cultured	_	VERB	_	Degree=Pos	_	_	_	_
37	NK	_	PROPN	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	population	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	clones	_	NOUN	_	Number=Plur	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	but	_	CCONJ	_	_	_	_	_	_
44	not	_	PART	_	_	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	freshly	_	ADV	_	_	_	_	_	_
47	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	cell	_	NOUN	_	Number=Sing	_	_	_	_
49	populations	_	NOUN	_	Number=Plur	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	NK	_	PROPN	_	Number=Sing	_	_	_	_
3	clones	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	lines	_	NOUN	_	Number=Plur	_	_	_	_
7	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	express	_	VERB	_	Degree=Pos	_	_	_	_
12	hGATA	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	3-specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	hGATA	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	3	_	NUM	_	NumType=Card	_	_	_	_
22	may	_	AUX	_	VerbForm=Fin	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	involved	_	ADJ	_	Degree=Pos	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	regulation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	unrearranged	_	ADJ	_	Degree=Pos	_	_	_	_
31	TcR	_	PROPN	_	Number=Sing	_	_	_	_
32	delta	_	NOUN	_	Number=Sing	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	NK	_	PROPN	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	RAG	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	could	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	all	_	DET	_	_	_	_	_	_
16	NK	_	PROPN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lines	_	NOUN	_	Number=Plur	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	clones	_	NOUN	_	Number=Plur	_	_	_	_
21	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011160	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	AT	_	ADP	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	CAML	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	member	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	tumor	_	NOUN	_	Number=Sing	_	_	_	_
15	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	AT	_	NOUN	_	_	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	key	_	ADJ	_	Degree=Pos	_	_	_	_
20	event	_	NOUN	_	Number=Sing	_	_	_	_
21	underlying	_	VERB	_	Degree=Pos	_	_	_	_
22	lymphocyte	_	ADJ	_	Number=Sing	_	_	_	_
23	action	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CAML	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	calcium	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	modulator	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	cyclophilin	_	NOUN	_	Number=Sing	_	_	_	_
9	ligand	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	coinducer	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	AT	_	ADP	_	_	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	when	_	ADV	_	PronType=Int	_	_	_	_
21	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	member	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	tumor	_	NOUN	_	Number=Sing	_	_	_	_
6	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	virtue	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	affinity	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	CAML	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Cross	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	linking	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	TACI	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	transmembrane	_	NOUN	_	Number=Sing	_	_	_	_
15	activator	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	CAML	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	interactor	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	surface	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	transfected	_	VERB	_	Degree=Pos	_	_	_	_
27	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	TACI	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	specific	_	ADJ	_	Degree=Pos	_	_	_	_
33	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
34	led	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	activation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	factors	_	NOUN	_	Number=Plur	_	_	_	_
41	NF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	AT	_	ADP	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	AP	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	TACI	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	AT	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	specifically	_	ADV	_	_	_	_	_	_
11	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	negative	_	ADJ	_	Degree=Pos	_	_	_	_
17	CAML	_	NOUN	_	Number=Sing	_	_	_	_
18	mutant	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	thus	_	ADV	_	_	_	_	_	_
21	implicating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	CAML	_	NOUN	_	Number=Sing	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
26	intermediate	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011161	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Distinct	_	ADJ	_	Degree=Pos	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	N	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	acetylcysteine	_	ADJ	_	Number=Sing	_	_	_	_
7	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	E-selectin	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	N-acetyl	_	PROPN	_	Number=Sing	_	_	_	_
8	-L	_	PUNCT	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	NAC	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	well	_	ADV	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	thiol	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	agonist	_	ADJ	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	EC	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	NAC	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	beta	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	not	_	ADV	_	_	_	_	_	_
17	basal	_	ADJ	_	Degree=Pos	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	50	_	NUM	_	NumType=Card	_	_	_	_
22	%	_	SYM	_	Number=Sing	_	_	_	_
23	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
24	at	_	ADP	_	_	_	_	_	_
25	approximately	_	ADV	_	_	_	_	_	_
26	20	_	NUM	_	NumType=Card	_	_	_	_
27	mM	_	NOUN	_	NumType=Card	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	EC	_	PROPN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TNF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	LPS	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
31	12	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	myristate	_	NOUN	_	Number=Sing	_	_	_	_
34	13	_	NUM	_	NumType=Card	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	acetate	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	PMA	_	PROPN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
41	similarly	_	ADV	_	_	_	_	_	_
42	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	NAC	_	PROPN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Unlike	_	ADP	_	_	_	_	_	_
2	published	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	pyrrolidinedithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	specifically	_	ADV	_	_	_	_	_	_
9	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
13	molecule	_	NOUN	_	Number=Sing	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	NAC	_	PROPN	_	Number=Sing	_	_	_	_
22	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	beta	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	surface	_	NOUN	_	Number=Sing	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	both	_	CCONJ	_	_	_	_	_	_
36	E-selectin	_	PROPN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	X	_	NumType=Card	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_
42	NAC	_	PROPN	_	Number=Sing	_	_	_	_
43	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
44	no	_	DET	_	_	_	_	_	_
45	effect	_	NOUN	_	Number=Sing	_	_	_	_
46	on	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	half	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	life	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	E-	_	PUNCT	_	Number=Sing	_	_	_	_
53	selectin	_	NOUN	_	Number=Sing	_	_	_	_
54	or	_	CCONJ	_	_	_	_	_	_
55	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	1	_	NUM	_	NumType=Card	_	_	_	_
58	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	NAC	_	PROPN	_	Number=Sing	_	_	_	_
3	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	EC	_	PROPN	_	Number=Sing	_	_	_	_
18	as	_	SCONJ	_	_	_	_	_	_
19	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	gel	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	shift	_	NOUN	_	Number=Sing	_	_	_	_
24	assays	_	NOUN	_	Number=Plur	_	_	_	_
25	using	_	VERB	_	VerbForm=Ger	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	oligonucleotide	_	ADJ	_	Number=Sing	_	_	_	_
28	probe	_	NOUN	_	Number=Sing	_	_	_	_
29	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	consensus	_	NOUN	_	Number=Sing	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
38	sites	_	NOUN	_	Number=Plur	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	1	_	NUM	_	NumType=Card	_	_	_	_
44	gene	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	NF	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	kappa	_	NOUN	_	Number=Sing	_	_	_	_
51	B	_	NOUN	_	Number=Sing	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
56	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
57	no	_	DET	_	_	_	_	_	_
58	appreciable	_	ADJ	_	Degree=Pos	_	_	_	_
59	effect	_	NOUN	_	Number=Sing	_	_	_	_
60	when	_	ADV	_	PronType=Int	_	_	_	_
61	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
62	oligomer	_	NOUN	_	Number=Sing	_	_	_	_
63	corresponding	_	VERB	_	Number=Sing	_	_	_	_
64	to	_	ADP	_	_	_	_	_	_
65	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
66	consensus	_	NOUN	_	Number=Sing	_	_	_	_
67	NF	_	PROPN	_	Number=Sing	_	_	_	_
68	-	_	PUNCT	_	_	_	_	_	_
69	kappa	_	NOUN	_	Number=Sing	_	_	_	_
70	B	_	NOUN	_	Number=Sing	_	_	_	_
71	binding	_	NOUN	_	Number=Sing	_	_	_	_
72	site	_	NOUN	_	Number=Sing	_	_	_	_
73	of	_	ADP	_	_	_	_	_	_
74	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
75	E-selectin	_	PROPN	_	Degree=Pos	_	_	_	_
76	gene	_	NOUN	_	Number=Sing	_	_	_	_
77	(	_	PUNCT	_	_	_	_	_	_
78	E-	_	PUNCT	_	_	_	_	_	_
79	selectin	_	NOUN	_	Number=Sing	_	_	_	_
80	-	_	PUNCT	_	_	_	_	_	_
81	NF	_	PROPN	_	Number=Sing	_	_	_	_
82	-	_	PUNCT	_	_	_	_	_	_
83	kappa	_	NOUN	_	Number=Sing	_	_	_	_
84	B	_	NOUN	_	Number=Sing	_	_	_	_
85	)	_	PUNCT	_	_	_	_	_	_
86	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
87	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
88	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	PROPN	_	Number=Sing	_	_	_	_
5	B	_	PROPN	_	Number=Sing	_	_	_	_
6	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	redox	_	NOUN	_	Number=Sing	_	_	_	_
12	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	effects	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	NAC	_	NOUN	_	Number=Sing	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	EC	_	NOUN	_	Number=Sing	_	_	_	_
23	redox	_	NOUN	_	Number=Sing	_	_	_	_
24	environment	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	NAC	_	PROPN	_	Number=Sing	_	_	_	_
2	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	expected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
6	increase	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	GSH	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	EC	_	PROPN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	whereas	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	affinity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	oligomer	_	NOUN	_	Number=Sing	_	_	_	_
24	peaked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	at	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	GSH	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	oxidized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	GSSG	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	ratio	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	approximately	_	ADV	_	_	_	_	_	_
39	200	_	NUM	_	NumType=Card	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	at	_	ADP	_	_	_	_	_	_
43	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
44	ratios	_	NOUN	_	Number=Plur	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	binding	_	NOUN	_	Number=Sing	_	_	_	_
48	to	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	E-selectin	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	NF	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	kappa	_	NOUN	_	Number=Sing	_	_	_	_
55	B	_	NOUN	_	Number=Sing	_	_	_	_
56	oligomer	_	NOUN	_	Number=Sing	_	_	_	_
57	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
58	relatively	_	ADV	_	_	_	_	_	_
59	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
60	even	_	ADV	_	_	_	_	_	_
61	at	_	ADP	_	_	_	_	_	_
62	ratios	_	NOUN	_	Number=Plur	_	_	_	_
63	>	_	PUNCT	_	_	_	_	_	_
64	400	_	NUM	_	NumType=Card	_	_	_	_
65	,	_	PUNCT	_	_	_	_	_	_
66	i.e.	_	X	_	_	_	_	_	_
67	,	_	PUNCT	_	_	_	_	_	_
68	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
69	achieved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
70	in	_	ADP	_	_	_	_	_	_
71	EC	_	PROPN	_	Number=Sing	_	_	_	_
72	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
73	with	_	ADP	_	_	_	_	_	_
74	40	_	NUM	_	NumType=Card	_	_	_	_
75	mM	_	NOUN	_	NumType=Card	_	_	_	_
76	NAC	_	NOUN	_	Number=Sing	_	_	_	_
77	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	PROPN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	consensus	_	NOUN	_	Number=Sing	_	_	_	_
13	sequences	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	E-selectin	_	ADJ	_	Degree=Pos	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	exhibits	_	NOUN	_	Number=Plur	_	_	_	_
23	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	differences	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	redox	_	NOUN	_	Degree=Pos	_	_	_	_
27	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	allowing	_	VERB	_	VerbForm=Ger	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	differential	_	ADJ	_	Degree=Pos	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	same	_	ADJ	_	Degree=Pos	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	factor	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	NAC	_	PROPN	_	Number=Sing	_	_	_	_
7	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	GSH	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	GSSG	_	PROPN	_	Number=Sing	_	_	_	_
14	ratio	_	NOUN	_	Number=Sing	_	_	_	_
15	within	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	EC	_	NOUN	_	Number=Sing	_	_	_	_
18	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	one	_	NUM	_	NumType=Card	_	_	_	_
20	possible	_	ADJ	_	Degree=Pos	_	_	_	_
21	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
22	through	_	ADP	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
26	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	agonist	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
31	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	EC	_	PROPN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011166	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Dual	_	ADJ	_	Degree=Pos	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	LPS	_	NOUN	_	Number=Sing	_	_	_	_
5	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	uptake	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	LPS	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	LPS	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	functions	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	recognize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
5	LPS	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	membrane	_	NOUN	_	Number=Sing	_	_	_	_
11	CD14	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	mCD14	_	NUM	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	LPS	_	NOUN	_	Number=Sing	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	anti-LPS	_	PROPN	_	_	_	_	_	_

1	Abs	_	NOUN	_	Number=Sing	_	_	_	_
2	neutralize	_	VERB	_	Number=Sing	_	_	_	_
3	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	SCONJ	_	_	_	_	_	_
5	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
6	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	uptake	_	NOUN	_	Number=Sing	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	mCD14	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Ab	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	changes	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	uptake	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	distribution	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	FITC	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	LPS	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	flow	_	NOUN	_	Number=Sing	_	_	_	_
19	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	laser	_	NOUN	_	Number=Sing	_	_	_	_
22	scanning	_	NOUN	_	Number=Sing	_	_	_	_
23	confocal	_	ADJ	_	Degree=Pos	_	_	_	_
24	microscopy	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	CD14	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	Chinese	_	ADJ	_	Degree=Pos	_	_	_	_
31	hamster	_	NOUN	_	Number=Sing	_	_	_	_
32	ovary	_	NOUN	_	Degree=Pos	_	_	_	_
33	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	CHO	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	CD14	_	PROPN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	human	_	ADJ	_	Degree=Pos	_	_	_	_
42	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
43	blood	_	NOUN	_	Number=Sing	_	_	_	_
44	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	PROPN	_	Number=Sing	_	_	_	_
2	core	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	O-side	_	ADJ	_	Degree=Pos	_	_	_	_
6	chain	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	mAbs	_	NOUN	_	Number=Plur	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	mCD14	_	NUM	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	LPS	_	NOUN	_	Number=Sing	_	_	_	_
15	uptake	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	both	_	DET	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	types	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	presence	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	serum	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	O	_	ADP	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	side	_	NOUN	_	Number=Sing	_	_	_	_
4	chain-specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	mAb	_	NOUN	_	Number=Sing	_	_	_	_
6	concurrently	_	ADV	_	_	_	_	_	_
7	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	complement	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	LPS	_	NOUN	_	Number=Sing	_	_	_	_
12	uptake	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	complement	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	CR1	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	uptake	_	VERB	_	Number=Sing	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	CHO	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	CD14	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
31	another	_	DET	_	_	_	_	_	_
32	heat	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	labile	_	ADJ	_	Degree=Pos	_	_	_	_
35	serum	_	NOUN	_	Number=Sing	_	_	_	_
36	factor	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	s	_	X	_	_	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	recognition	_	NOUN	_	Number=Sing	_	_	_	_
45	molecule	_	NOUN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	s	_	X	_	_	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Core-specific	_	ADJ	_	Degree=Pos	_	_	_	_
2	mAb	_	NOUN	_	Number=Sing	_	_	_	_
3	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	mCD14	_	NUM	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	uptake	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
12	LPS	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	while	_	SCONJ	_	_	_	_	_	_
15	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	less	_	ADV	_	Degree=Cmp	_	_	_	_
17	concurrent	_	ADJ	_	Degree=Pos	_	_	_	_
18	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	non-mCD14	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
23	LPS	_	NOUN	_	Number=Sing	_	_	_	_
24	uptake	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	modulation	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	anti-LPS	_	NOUN	_	Number=Sing	_	_	_	_
5	mAbs	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	mCD14	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
10	LPS	_	NOUN	_	Number=Sing	_	_	_	_
11	uptake	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	LPS	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	translocation	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	TNF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	secretion	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	CHO	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	CD14	_	PROPN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	respectively	_	ADV	_	_	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	while	_	SCONJ	_	_	_	_	_	_
46	mAb	_	NOUN	_	Number=Sing	_	_	_	_
47	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	non-mCD14	_	ADJ	_	Degree=Pos	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
52	LPS	_	NOUN	_	Number=Sing	_	_	_	_
53	uptake	_	NOUN	_	Number=Sing	_	_	_	_
54	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
55	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
56	activities	_	NOUN	_	Number=Plur	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_

1	Abs	_	NOUN	_	_	_	_	_	_
2	thus	_	ADV	_	_	_	_	_	_
3	mediate	_	ADJ	_	Degree=Pos	_	_	_	_
4	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	functions	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	respectively	_	ADV	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	by	_	SCONJ	_	_	_	_	_	_
12	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	target	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	uptake	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	LPS	_	NOUN	_	Number=Plur	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	mCD14	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	augmenting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	uptake	_	NOUN	_	Number=Sing	_	_	_	_
23	through	_	ADP	_	_	_	_	_	_
24	CR1	_	NOUN	_	Number=Sing	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	other	_	ADJ	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	receptors	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011171	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	IkappaB	_	ADJ	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	diminished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	NF	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	following	_	VERB	_	VerbForm=Ger	_	_	_	_
15	hydrocortisone	_	NOUN	_	Number=Sing	_	_	_	_
16	injection	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	recently	_	ADV	_	_	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	hydrocortisone	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	other	_	ADJ	_	Degree=Pos	_	_	_	_
9	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
10	inhibit	_	VERB	_	Number=Sing	_	_	_	_
11	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
12	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
13	species	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	ROS	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	generation	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	mononuclear	_	ADJ	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	MNC	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	polymorphonuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	leucocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	PMNL	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	NF-	_	PROPN	_	Number=Sing	_	_	_	_
3	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
4	/	_	PUNCT	_	_	_	_	_	_
5	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
6	system	_	NOUN	_	Number=Sing	_	_	_	_
7	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	genes	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	including	_	VERB	_	VerbForm=Ger	_	_	_	_
15	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
16	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	ROS	_	NOUN	_	Number=Sing	_	_	_	_
19	generation	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
22	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	hydrocortisone	_	NOUN	_	Number=Sing	_	_	_	_
27	may	_	AUX	_	VerbForm=Fin	_	_	_	_
28	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
29	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
30	production	_	NOUN	_	Number=Sing	_	_	_	_
31	thus	_	ADV	_	_	_	_	_	_
32	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
36	translocation	_	NOUN	_	Number=Sing	_	_	_	_
37	from	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
40	into	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	MNC	_	PROPN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	vivo	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	hundred	_	NUM	_	NumType=Card	_	_	_	_
3	milligram	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	hydrocortisone	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	injected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	intravenously	_	ADV	_	_	_	_	_	_
9	into	_	ADP	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	normal	_	ADJ	_	Degree=Pos	_	_	_	_
12	subjects	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Blood	_	NOUN	_	Number=Sing	_	_	_	_
2	samples	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	prior	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	injection	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	8	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	24	_	NUM	_	NumType=Card	_	_	_	_
20	hr	_	NOUN	_	Number=Sing	_	_	_	_
21	after	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	injection	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	extracts	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	total	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	lysates	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	prepared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	MNC	_	PROPN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	standard	_	ADJ	_	Degree=Pos	_	_	_	_
13	techniques	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	IkappaB	_	ADJ	_	Number=Sing	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	MNC	_	PROPN	_	Number=Sing	_	_	_	_
5	homogenates	_	NOUN	_	Number=Plur	_	_	_	_
6	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	at	_	ADP	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	hr	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	peaked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	hr	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	started	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	decrease	_	VERB	_	VerbForm=Inf	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	8	_	NUM	_	NumType=Card	_	_	_	_
23	hr	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	returned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	baseline	_	NOUN	_	Number=Sing	_	_	_	_
29	levels	_	NOUN	_	Number=Plur	_	_	_	_
30	at	_	ADP	_	_	_	_	_	_
31	24	_	NUM	_	NumType=Card	_	_	_	_
32	hr	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	MNC	_	PROPN	_	Number=Sing	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	extracts	_	NOUN	_	Number=Plur	_	_	_	_
8	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	hr	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	reached	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	nadir	_	NOUN	_	Number=Sing	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	4	_	NUM	_	NumType=Card	_	_	_	_
18	hr	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	gradually	_	ADV	_	_	_	_	_	_
21	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	at	_	ADP	_	_	_	_	_	_
23	8	_	NUM	_	NumType=Card	_	_	_	_
24	hr	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	returned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	back	_	ADV	_	_	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	baseline	_	NOUN	_	Number=Sing	_	_	_	_
30	levels	_	NOUN	_	Number=Plur	_	_	_	_
31	at	_	ADP	_	_	_	_	_	_
32	24	_	NUM	_	NumType=Card	_	_	_	_
33	hr	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	total	_	ADJ	_	Degree=Pos	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	content	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	subunit	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	P65	_	NUM	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	MNC	_	PROPN	_	Number=Sing	_	_	_	_
15	lysates	_	NOUN	_	Number=Plur	_	_	_	_
16	also	_	ADV	_	_	_	_	_	_
17	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	decrease	_	NOUN	_	Number=Sing	_	_	_	_
20	following	_	VERB	_	VerbForm=Ger	_	_	_	_
21	hydrocortisone	_	NOUN	_	Number=Sing	_	_	_	_
22	injection	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	decrease	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	hr	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	reached	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	nadir	_	NOUN	_	Number=Sing	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	hr	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	returned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	baseline	_	NOUN	_	Number=Sing	_	_	_	_
20	levels	_	NOUN	_	Number=Plur	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	24	_	NUM	_	NumType=Card	_	_	_	_
23	hr	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	ROS	_	PROPN	_	Number=Sing	_	_	_	_
2	generation	_	NOUN	_	Number=Sing	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	paralleled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	at	_	ADP	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	hr	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	reached	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	nadir	_	NOUN	_	Number=Sing	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	hr	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	started	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	8	_	NUM	_	NumType=Card	_	_	_	_
22	hr	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	returned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	basal	_	ADJ	_	Degree=Pos	_	_	_	_
28	levels	_	NOUN	_	Number=Plur	_	_	_	_
29	at	_	ADP	_	_	_	_	_	_
30	24	_	NUM	_	NumType=Card	_	_	_	_
31	hr	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	hydrocortisone	_	NOUN	_	Number=Sing	_	_	_	_
6	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	MNC	_	PROPN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	parallel	_	PROPN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	translocation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	into	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
13	thus	_	ADV	_	_	_	_	_	_
14	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011179	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Anaphylatoxins	_	PROPN	_	_	_	_	_	_
2	C5a	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	C3a	_	PROPN	_	Number=Sing	_	_	_	_
5	induce	_	VERB	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
13	blood	_	NOUN	_	Number=Sing	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	anaphylatoxins	_	PROPN	_	Number=Plur	_	_	_	_
3	C5a	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	C3a	_	PROPN	_	Number=Sing	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	involved	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	capability	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	C5a	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	C3a	_	PROPN	_	Number=Sing	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	C5a	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	C3a	_	PROPN	_	Number=Sing	_	_	_	_
4	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
8	blood	_	NOUN	_	Number=Sing	_	_	_	_
9	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	specificity	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	sequence	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	p50	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	p65	_	NUM	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	constituents	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	prototypic	_	ADJ	_	Degree=Pos	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	components	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	complexes	_	NOUN	_	Number=Plur	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	anti-peptide	_	ADJ	_	Degree=Pos	_	_	_	_
27	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	gel	_	NOUN	_	Number=Sing	_	_	_	_
30	supershift	_	NOUN	_	Number=Sing	_	_	_	_
31	assays	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	C5a	_	PROPN	_	Number=Sing	_	_	_	_
2	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	15	_	NUM	_	NumType=Card	_	_	_	_
9	min	_	NOUN	_	Number=Plur	_	_	_	_
10	after	_	ADP	_	_	_	_	_	_
11	agonist	_	ADJ	_	Number=Sing	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	peaked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	30	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	40	_	NUM	_	NumType=Card	_	_	_	_
19	min	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
24	at	_	ADP	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	h	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	VERB	_	VerbForm=Ger	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	kappaB	_	VERB	_	Number=Sing	_	_	_	_
4	sequence	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	initial	_	ADJ	_	Degree=Pos	_	_	_	_
10	decrease	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
13	increase	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
17	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
18	levels	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	as	_	SCONJ	_	_	_	_	_	_
21	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	Western	_	ADJ	_	Degree=Pos	_	_	_	_
24	blotting	_	NOUN	_	Number=Sing	_	_	_	_
25	using	_	VERB	_	VerbForm=Ger	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	anti-IkappaBalpha	_	ADJ	_	Degree=Pos	_	_	_	_
28	antibody	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Pertussis	_	PROPN	_	Number=Sing	_	_	_	_
2	toxin	_	NOUN	_	Number=Sing	_	_	_	_
3	treatment	_	NOUN	_	Number=Sing	_	_	_	_
4	markedly	_	ADV	_	_	_	_	_	_
5	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	activities	_	NOUN	_	Number=Plur	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	C5a	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	C3a	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	whereas	_	SCONJ	_	_	_	_	_	_
17	cholera	_	NOUN	_	Number=Sing	_	_	_	_
18	toxin	_	NOUN	_	Number=Sing	_	_	_	_
19	displayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	no	_	DET	_	_	_	_	_	_
21	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
22	effect	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Neither	_	DET	_	_	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	toxins	_	NOUN	_	Number=Plur	_	_	_	_
6	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	same	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	imply	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	potential	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	anaphylatoxins	_	PROPN	_	Number=Sing	_	_	_	_
10	C5a	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	C3a	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	SCONJ	_	_	_	_	_	_
14	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	G	_	PROPN	_	Number=Sing	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011186	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Platelet	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	heparin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
12	epidermal	_	ADJ	_	Degree=Pos	_	_	_	_
13	growth	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	like	_	ADP	_	Degree=Pos	_	_	_	_
17	growth	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Correlation	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
3	blood	_	NOUN	_	Number=Sing	_	_	_	_
4	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	responded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	platelet	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	PAF	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	up	_	ADP	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	transcript	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	heparin	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
27	epidermal	_	ADJ	_	Degree=Pos	_	_	_	_
28	growth	_	NOUN	_	Number=Sing	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	like	_	ADP	_	Degree=Pos	_	_	_	_
32	growth	_	NOUN	_	Number=Sing	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	HB	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	EGF	_	PROPN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	potent	_	ADJ	_	Degree=Pos	_	_	_	_
42	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
43	for	_	ADP	_	_	_	_	_	_
44	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
45	smooth	_	ADJ	_	Degree=Pos	_	_	_	_
46	muscle	_	NOUN	_	Number=Sing	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	function	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	PAF	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	at	_	ADP	_	_	_	_	_	_
8	nanomolar	_	ADJ	_	Degree=Pos	_	_	_	_
9	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	ligand	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	starting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	30	_	NUM	_	NumType=Card	_	_	_	_
17	min	_	NOUN	_	Number=Plur	_	_	_	_
18	after	_	ADP	_	_	_	_	_	_
19	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	PAF	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	up	_	ADP	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HB	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	EGF	_	PROPN	_	Number=Sing	_	_	_	_
12	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	increase	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	kappa	_	PROPN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	functions	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	PAF	_	NOUN	_	Number=Sing	_	_	_	_
5	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	surface	_	NOUN	_	Number=Sing	_	_	_	_
13	PAF	_	NOUN	_	Number=Sing	_	_	_	_
14	receptors	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	PAF	_	NOUN	_	Number=Sing	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	antagonists	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	WEB	_	PROPN	_	Number=Sing	_	_	_	_
23	2086	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	L-659,989	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	both	_	CCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	up	_	ADP	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	regulation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	HB	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	EGF	_	PROPN	_	Number=Sing	_	_	_	_
37	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	kappa	_	NOUN	_	Number=Sing	_	_	_	_
40	B	_	NOUN	_	Number=Sing	_	_	_	_
41	binding	_	NOUN	_	Number=Sing	_	_	_	_
42	activity	_	NOUN	_	Number=Sing	_	_	_	_
43	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	by	_	ADP	_	_	_	_	_	_
45	PAF	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	antagonists	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	however	_	ADV	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	no	_	DET	_	_	_	_	_	_
8	effect	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
11	ester	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	up	_	ADP	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	HB	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	EGF	_	PROPN	_	Number=Sing	_	_	_	_
21	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	pertussis	_	NOUN	_	Number=Sing	_	_	_	_
6	toxin	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	functions	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	PAF	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	whereas	_	SCONJ	_	_	_	_	_	_
14	cholera	_	NOUN	_	Number=Sing	_	_	_	_
15	toxin	_	NOUN	_	Number=Sing	_	_	_	_
16	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	no	_	DET	_	_	_	_	_	_
18	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
19	effect	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Pyrrolidine	_	PROPN	_	Number=Sing	_	_	_	_
2	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	markedly	_	ADV	_	_	_	_	_	_
14	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	PAF	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	as	_	ADV	_	_	_	_	_	_
23	well	_	ADV	_	Degree=Pos	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	up	_	ADP	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	regulation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	HB	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	EGF	_	PROPN	_	Number=Sing	_	_	_	_
32	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	potential	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	PAF	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	HB	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	EGF	_	PROPN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	evidence	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
22	through	_	ADP	_	_	_	_	_	_
23	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011190	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	down	_	ADP	_	_	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	independent	_	ADJ	_	Degree=Pos	_	_	_	_
16	pathways	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	lymphoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
22	tumor	_	NOUN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	line	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	lymphoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	Molt4	_	PROPN	_	Number=Sing	_	_	_	_
13	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	down	_	ADV	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	after	_	ADP	_	_	_	_	_	_
23	exposure	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	dimethyl	_	ADJ	_	Degree=Pos	_	_	_	_
26	sulfoxide	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
30	myristate	_	NOUN	_	Number=Sing	_	_	_	_
31	acetate	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	calcium	_	NOUN	_	Number=Sing	_	_	_	_
37	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
38	A23187	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	which	_	PRON	_	PronType=Rel	_	_	_	_
41	raises	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
44	calcium	_	NOUN	_	Number=Sing	_	_	_	_
45	concentration	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	block	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	RNA	_	PROPN	_	Number=Sing	_	_	_	_
5	elongation	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	largely	_	ADV	_	_	_	_	_	_
8	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	c-myc	_	ADJ	_	Number=Sing	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	negative	_	ADJ	_	Degree=Pos	_	_	_	_
3	regulation	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	dimethyl	_	ADJ	_	Degree=Pos	_	_	_	_
6	sulfoxide	_	NOUN	_	Number=Sing	_	_	_	_
7	takes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	place	_	NOUN	_	Number=Sing	_	_	_	_
9	even	_	ADV	_	_	_	_	_	_
10	when	_	ADV	_	PronType=Int	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
20	myristate	_	NOUN	_	Number=Sing	_	_	_	_
21	acetate	_	NOUN	_	Degree=Pos	_	_	_	_
22	effect	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	some	_	DET	_	_	_	_	_	_
27	extent	_	NOUN	_	Number=Sing	_	_	_	_
28	only	_	ADV	_	_	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	calcium	_	NOUN	_	Number=Sing	_	_	_	_
3	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
7	suppression	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	however	_	ADV	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	strictly	_	ADV	_	_	_	_	_	_
12	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	de	_	PROPN	_	Number=Sing	_	_	_	_
14	novo	_	X	_	Number=Sing	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	two	_	NUM	_	NumType=Card	_	_	_	_
4	different	_	ADJ	_	Degree=Pos	_	_	_	_
5	negative	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	pathways	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	involved	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	one	_	NUM	_	NumType=Card	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	independent	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	one	_	NUM	_	NumType=Card	_	_	_	_
20	which	_	PRON	_	PronType=Int	_	_	_	_
21	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	de	_	X	_	Number=Sing	_	_	_	_
24	novo	_	PROPN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	latter	_	ADJ	_	Degree=Pos	_	_	_	_
3	one	_	NOUN	_	Number=Sing	_	_	_	_
4	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	rapidly	_	ADV	_	_	_	_	_	_
11	calcium	_	ADJ	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	product	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011192	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	Runt	_	NOUN	_	Number=Sing	_	_	_	_
5	domain	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
8	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	during	_	ADP	_	_	_	_	_	_
15	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
16	development	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	A	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	PEBP2	_	PROPN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	encode	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	binding	_	VERB	_	Number=Sing	_	_	_	_
15	subunit	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	murine	_	NOUN	_	Number=Sing	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	PEBP2	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	specific	_	ADJ	_	Degree=Pos	_	_	_	_
32	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
33	regulator	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	related	_	ADJ	_	Degree=Pos	_	_	_	_
4	genes	_	NOUN	_	Number=Plur	_	_	_	_
5	share	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	evolutionarily	_	ADV	_	_	_	_	_	_
8	conserved	_	VERB	_	Degree=Pos	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	Runt	_	NOUN	_	Number=Sing	_	_	_	_
13	domain	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	PEBP2	_	PROPN	_	Number=Sing	_	_	_	_
2	alpha	_	NOUN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	murine	_	NOUN	_	Number=Sing	_	_	_	_
5	counterpart	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	AML1	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	breakpoints	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	8;21	_	NUM	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	3;21	_	NUM	_	NumType=Card	_	_	_	_
21	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
22	translocations	_	NOUN	_	Number=Plur	_	_	_	_
23	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	acute	_	ADJ	_	Degree=Pos	_	_	_	_
26	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
27	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	RNA	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	blots	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	various	_	ADJ	_	Degree=Pos	_	_	_	_
8	adult	_	NOUN	_	Number=Sing	_	_	_	_
9	mouse	_	NOUN	_	Number=Sing	_	_	_	_
10	tissues	_	NOUN	_	Number=Plur	_	_	_	_
11	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	both	_	DET	_	_	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	most	_	ADV	_	_	_	_	_	_
22	prominent	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	thymus	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	A	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	mouse	_	NOUN	_	Number=Sing	_	_	_	_
10	AML1	_	PROPN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T	_	PROPN	_	Number=Sing	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	thymuses	_	NOUN	_	Number=Plur	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	day	_	NOUN	_	Number=Sing	_	_	_	_
25	16	_	NUM	_	NumType=Card	_	_	_	_
26	embryos	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	newborns	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	as	_	ADV	_	_	_	_	_	_
31	well	_	ADV	_	Degree=Pos	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	4	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	week	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	old	_	ADJ	_	Degree=Pos	_	_	_	_
38	adult	_	NOUN	_	Number=Sing	_	_	_	_
39	mice	_	NOUN	_	Number=Plur	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	situ	_	NOUN	_	Number=Sing	_	_	_	_
44	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	genes	_	NOUN	_	Number=Plur	_	_	_	_
6	persisted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
9	lymph	_	NOUN	_	Number=Sing	_	_	_	_
10	nodes	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	adult	_	NOUN	_	Number=Sing	_	_	_	_
13	mice	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	all	_	DET	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	CD4	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CD8	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	CD4	_	PROPN	_	Number=Sing	_	_	_	_
14	+	_	SYM	_	_	_	_	_	_
15	CD8	_	NOUN	_	Number=Sing	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	CD4	_	PROPN	_	Number=Sing	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	CD8	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	CD4	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	CD8	_	NOUN	_	Number=Sing	_	_	_	_
27	+	_	SYM	_	_	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	populations	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	both	_	DET	_	_	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	throughout	_	ADP	_	_	_	_	_	_
13	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	development	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	supporting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	notion	_	NOUN	_	Number=Sing	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	PEBP2	_	PROPN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Transcripts	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	mouse	_	NOUN	_	Number=Sing	_	_	_	_
4	AML1	_	PROPN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_

1	B	_	PRON	_	Number=Sing	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	day	_	NOUN	_	Number=Sing	_	_	_	_
7	12	_	NUM	_	NumType=Card	_	_	_	_
8	fetal	_	ADJ	_	Number=Sing	_	_	_	_
9	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
10	liver	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	bone	_	NOUN	_	Number=Sing	_	_	_	_
15	marrow	_	ADJ	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	newborn	_	ADJ	_	Degree=Pos	_	_	_	_
19	mice	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	implication	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	mouse	_	NOUN	_	Number=Sing	_	_	_	_
5	AML1	_	PROPN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	other	_	ADJ	_	Degree=Pos	_	_	_	_
15	than	_	ADP	_	_	_	_	_	_
16	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
19	lineage	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	relation	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
26	leukemogenesis	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011198	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
6	colony	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	E	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	selectin	_	VERB	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
20	A	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	originally	_	ADV	_	_	_	_	_	_
12	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	athat	_	PRON	_	PronType=Rel	_	_	_	_
21	supported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	mediated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	immunoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
32	effects	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
35	A	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	CsA	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	antiinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	properties	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	CsA	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Significantly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CsA	_	PROPN	_	Number=Sing	_	_	_	_
4	completely	_	ADV	_	_	_	_	_	_
5	suppressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
21	colony	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	GM	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	CSF	_	PROPN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
32	elements	_	NOUN	_	Number=Plur	_	_	_	_
33	that	_	PRON	_	PronType=Rel	_	_	_	_
34	use	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	60	_	NUM	_	NumType=Card	_	_	_	_
38	%	_	SYM	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	CsA	_	NOUN	_	Number=Sing	_	_	_	_
2	similarly	_	ADV	_	_	_	_	_	_
3	mediated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	reduction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	up	_	ADP	_	_	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	65	_	NUM	_	NumType=Card	_	_	_	_
10	%	_	SYM	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	GM	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	CSF	_	PROPN	_	Number=Sing	_	_	_	_
15	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	CsA	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	E-selectin	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	but	_	CCONJ	_	_	_	_	_	_
7	not	_	ADV	_	_	_	_	_	_
8	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
11	molecule	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	even	_	ADV	_	_	_	_	_	_
25	though	_	SCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	E	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	selectin	_	NOUN	_	Number=Sing	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappa	_	NOUN	_	Number=Sing	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	rather	_	ADV	_	_	_	_	_	_
39	than	_	ADP	_	_	_	_	_	_
40	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Hence	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	surface	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
12	molecule	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	tumor	_	NOUN	_	Number=Sing	_	_	_	_
15	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	TNF	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	40	_	NUM	_	NumType=Card	_	_	_	_
26	%	_	SYM	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	presence	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	CsA	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	reflected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	29	_	NUM	_	NumType=Card	_	_	_	_
40	%	_	SYM	_	Number=Sing	_	_	_	_
41	decrease	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	neutrophil	_	ADJ	_	Number=Sing	_	_	_	_
44	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	CsA	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
14	structure	_	NOUN	_	Number=Sing	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	DNasel	_	PROPN	_	Number=Sing	_	_	_	_
19	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
20	sites	_	NOUN	_	Number=Plur	_	_	_	_
21	within	_	ADP	_	_	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	GM	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	CSF	_	PROPN	_	Number=Sing	_	_	_	_
27	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	E-selectin	_	ADJ	_	Number=Sing	_	_	_	_
31	promoter	_	NOUN	_	Number=Sing	_	_	_	_
32	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	CsA	_	PROPN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
5	report	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	CsA	_	NOUN	_	Number=Sing	_	_	_	_
17	could	_	AUX	_	VerbForm=Fin	_	_	_	_
18	function	_	VERB	_	VerbForm=Inf	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	antiinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	agent	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011203	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cross	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	linking	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	CD44	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	rheumatoid	_	VERB	_	Number=Sing	_	_	_	_
8	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	up	_	ADP	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_
17	CD44	_	PROPN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
21	molecule	_	NOUN	_	Number=Sing	_	_	_	_
22	also	_	ADV	_	_	_	_	_	_
23	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	hyaluronic	_	ADJ	_	Number=Sing	_	_	_	_
26	acid	_	NOUN	_	Number=Sing	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	homing	_	VERB	_	Number=Sing	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	functions	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	example	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	rheumatoid	_	VERB	_	Degree=Pos	_	_	_	_
16	synovitis	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	currently	_	ADV	_	_	_	_	_	_
20	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	novel	_	NOUN	_	Number=Sing	_	_	_	_
9	function	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	CD44	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	rheumatoid	_	ADJ	_	Number=Sing	_	_	_	_
6	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	RA	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	patients	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	CD44	_	PROPN	_	Number=Sing	_	_	_	_
16	cross	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	linking	_	VERB	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	hyaluronan	_	PROPN	_	Number=Sing	_	_	_	_
23	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	subsequently	_	ADV	_	_	_	_	_	_
30	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	mediated	_	VERB	_	Degree=Pos	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Briefly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	1	_	X	_	_	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	rheumatoid	_	VERB	_	Degree=Pos	_	_	_	_
9	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	highly	_	ADV	_	_	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	CD44	_	PROPN	_	Number=Sing	_	_	_	_
14	;	_	PUNCT	_	_	_	_	_	_
15	2	_	X	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	cross	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	linking	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	CD44	_	PROPN	_	Number=Sing	_	_	_	_
22	markedly	_	ADV	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	transiently	_	ADV	_	_	_	_	_	_
25	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
32	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	much	_	ADV	_	_	_	_	_	_
35	more	_	ADJ	_	Degree=Cmp	_	_	_	_
36	than	_	ADP	_	_	_	_	_	_
37	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	IL	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1beta	_	PROPN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	TNF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	alpha	_	NOUN	_	Number=Sing	_	_	_	_
45	;	_	PUNCT	_	_	_	_	_	_
46	3	_	X	_	NumType=Card	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	hyaluronan	_	PROPN	_	Number=Sing	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	especially	_	ADV	_	_	_	_	_	_
51	when	_	ADV	_	PronType=Int	_	_	_	_
52	fragmented	_	ADJ	_	Degree=Pos	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	also	_	ADV	_	_	_	_	_	_
55	up	_	ADP	_	_	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
58	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	1	_	NUM	_	NumType=Card	_	_	_	_
61	;	_	PUNCT	_	_	_	_	_	_
62	4	_	NUM	_	NumType=Card	_	_	_	_
63	)	_	PUNCT	_	_	_	_	_	_
64	CD44	_	PROPN	_	Number=Sing	_	_	_	_
65	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
66	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
67	transcription	_	NOUN	_	Number=Sing	_	_	_	_
68	factor	_	NOUN	_	Number=Sing	_	_	_	_
69	AP	_	NOUN	_	Number=Sing	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	1	_	NUM	_	NumType=Card	_	_	_	_
72	;	_	PUNCT	_	_	_	_	_	_
73	and	_	CCONJ	_	_	_	_	_	_
74	5	_	X	_	NumType=Card	_	_	_	_
75	)	_	PUNCT	_	_	_	_	_	_
76	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
77	integrin	_	NOUN	_	Number=Sing	_	_	_	_
78	-	_	PUNCT	_	_	_	_	_	_
79	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
80	adhesive	_	ADJ	_	Degree=Pos	_	_	_	_
81	function	_	NOUN	_	Number=Sing	_	_	_	_
82	of	_	ADP	_	_	_	_	_	_
83	RA	_	PROPN	_	Number=Sing	_	_	_	_
84	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
85	cells	_	NOUN	_	Number=Plur	_	_	_	_
86	to	_	ADP	_	_	_	_	_	_
87	T	_	PROPN	_	Number=Sing	_	_	_	_
88	cells	_	NOUN	_	Number=Plur	_	_	_	_
89	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
90	also	_	ADV	_	_	_	_	_	_
91	amplified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
92	by	_	ADP	_	_	_	_	_	_
93	CD44	_	PROPN	_	Number=Sing	_	_	_	_
94	cross	_	NOUN	_	Number=Sing	_	_	_	_
95	-	_	PUNCT	_	_	_	_	_	_
96	linking	_	NOUN	_	Number=Sing	_	_	_	_
97	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	RA	_	PROPN	_	Number=Sing	_	_	_	_
9	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	matrices	_	VERB	_	Number=Plur	_	_	_	_
13	such	_	ADJ	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	hyaluronic	_	ADJ	_	Number=Sing	_	_	_	_
16	acid	_	NOUN	_	Number=Sing	_	_	_	_
17	through	_	ADP	_	_	_	_	_	_
18	CD44	_	PROPN	_	Number=Sing	_	_	_	_
19	could	_	AUX	_	VerbForm=Fin	_	_	_	_
20	up	_	ADV	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
33	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	T	_	PROPN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	which	_	PRON	_	PronType=Rel	_	_	_	_
39	might	_	AUX	_	VerbForm=Fin	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	turn	_	VERB	_	VerbForm=Inf	_	_	_	_
42	cause	_	VERB	_	_	_	_	_	_
43	activation	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	T	_	ADJ	_	Number=Sing	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
49	cells	_	NOUN	_	Number=Plur	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	RA	_	PROPN	_	Number=Sing	_	_	_	_
52	synovitis	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	such	_	ADJ	_	Degree=Pos	_	_	_	_
6	cross	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	talking	_	VERB	_	VerbForm=Ger	_	_	_	_
9	among	_	ADP	_	_	_	_	_	_
10	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
11	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
12	molecules	_	NOUN	_	Number=Plur	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	involved	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	including	_	VERB	_	VerbForm=Ger	_	_	_	_
23	RA	_	NOUN	_	Number=Sing	_	_	_	_
24	synovitis	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011207	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Suppression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	program	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
9	esters	_	NOUN	_	Number=Plur	_	_	_	_
10	coincides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	E2	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
30	element	_	NOUN	_	Number=Sing	_	_	_	_
31	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	specific	_	ADJ	_	Degree=Pos	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	hemin	_	NOUN	_	Number=Sing	_	_	_	_
4	increases	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	while	_	SCONJ	_	_	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	13	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	acetate	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TPA	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	represses	_	VERB	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	specific	_	ADJ	_	Degree=Pos	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	line	_	NOUN	_	Number=Sing	_	_	_	_
29	K562	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	hemin	_	NOUN	_	Number=Sing	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	TPA	_	PROPN	_	Number=Sing	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	element	_	NOUN	_	Number=Sing	_	_	_	_
22	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	within	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
26	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	sequences	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	many	_	ADJ	_	Degree=Pos	_	_	_	_
30	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	specific	_	ADJ	_	Degree=Pos	_	_	_	_
33	genes	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	TPA	_	PROPN	_	Number=Sing	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
8	AP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	TPA	_	PROPN	_	Number=Sing	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	lineage	_	NOUN	_	Number=Sing	_	_	_	_
9	limited	_	ADJ	_	Degree=Pos	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	E2	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	control	_	NOUN	_	Number=Sing	_	_	_	_
19	element	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Hemin	_	NOUN	_	Number=Sing	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	K562	_	NUM	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	facilitate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	E2	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	recognition	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Hemin	_	PROPN	_	Number=Sing	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	nonspecifically	_	ADV	_	_	_	_	_	_
6	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transiently	_	ADV	_	_	_	_	_	_
11	transfected	_	VERB	_	Degree=Pos	_	_	_	_
12	genes	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	K562	_	NUM	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Beyond	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	nonspecific	_	ADJ	_	Degree=Pos	_	_	_	_
4	increase	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	hemin	_	NOUN	_	Number=Sing	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	lineage	_	NOUN	_	Number=Sing	_	_	_	_
19	limited	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	E2	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	divergent	_	ADJ	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	hemin	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	TPA	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	K562	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	part	_	ADJ	_	Degree=Pos	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	contrasting	_	ADJ	_	Degree=Pos	_	_	_	_
23	effects	_	NOUN	_	Number=Plur	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	E2	_	PROPN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011213	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	LIM	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Hox	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	hLH	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	aberrantly	_	ADV	_	_	_	_	_	_
15	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	chronic	_	ADJ	_	Number=Sing	_	_	_	_
18	myelogenous	_	ADJ	_	Degree=Pos	_	_	_	_
19	leukaemia	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	9q33	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	SYM	_	_	_	_	_	_
25	34.1	_	NUM	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	isolation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	LH	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	putative	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	two	_	NUM	_	NumType=Card	_	_	_	_
17	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	rich	_	ADJ	_	Degree=Pos	_	_	_	_
20	regions	_	NOUN	_	Number=Plur	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	LIM	_	PROPN	_	Number=Sing	_	_	_	_
23	domains	_	NOUN	_	Number=Plur	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	homeobox	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	Hox	_	PROPN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	DNA	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	binding	_	VERB	_	Number=Sing	_	_	_	_
34	domain	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	High	_	ADJ	_	Degree=Pos	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	hLH	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	all	_	DET	_	_	_	_	_	_
12	cases	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	chronic	_	ADJ	_	Number=Sing	_	_	_	_
15	myelogenous	_	ADJ	_	Degree=Pos	_	_	_	_
16	leukaemia	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	CML	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	regardless	_	ADV	_	_	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	disease	_	NOUN	_	Number=Sing	_	_	_	_
25	status	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	hLH	_	INTJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	mapped	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	chromosome	_	VERB	_	Number=Sing	_	_	_	_
8	9Q33	_	NUM	_	Number=Sing	_	_	_	_
9	-	_	SYM	_	_	_	_	_	_
10	34.1	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	same	_	ADJ	_	Degree=Pos	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	reciprocal	_	ADJ	_	Degree=Pos	_	_	_	_
19	translocation	_	NOUN	_	Number=Sing	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	creates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	BCR	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	ABL	_	PROPN	_	Number=Sing	_	_	_	_
26	chimera	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	Philadelphia	_	PROPN	_	Number=Sing	_	_	_	_
30	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	Ph	_	NOUN	_	Number=Sing	_	_	_	_
33	'	_	PUNCT	_	_	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	hallmark	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	CML	_	PROPN	_	Number=Sing	_	_	_	_
40	;	_	PUNCT	_	_	_	_	_	_
41	hLH	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	2	_	NUM	_	NumType=Card	_	_	_	_
44	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
45	retained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
46	on	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	derivative	_	ADJ	_	Number=Sing	_	_	_	_
49	9	_	NUM	_	NumType=Card	_	_	_	_
50	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
53	therefore	_	ADV	_	_	_	_	_	_
54	centromeric	_	ADJ	_	Number=Sing	_	_	_	_
55	of	_	ADP	_	_	_	_	_	_
56	c	_	NOUN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	ABL	_	PROPN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	proximity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	hLH	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	breakpoint	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
12	9	_	NUM	_	NumType=Card	_	_	_	_
13	raises	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	possibility	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	cis	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	t(9	_	NUM	_	Number=Sing	_	_	_	_
23	;	_	PUNCT	_	_	_	_	_	_
24	22	_	NUM	_	NumType=Card	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	q34	_	NUM	_	NumType=Card	_	_	_	_
28	;	_	PUNCT	_	_	_	_	_	_
29	q11	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	translocation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	SCONJ	_	_	_	_	_	_
4	finding	_	VERB	_	VerbForm=Ger	_	_	_	_
5	hLH	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	all	_	DET	_	_	_	_	_	_
11	cases	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	CML	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
20	malignancies	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	lines	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	primary	_	ADJ	_	Degree=Pos	_	_	_	_
30	cases	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	acute	_	ADJ	_	Degree=Pos	_	_	_	_
33	myelogenous	_	ADJ	_	Degree=Pos	_	_	_	_
34	leukaemia	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	hLH	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	development	_	NOUN	_	Number=Sing	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	progression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	leukaemia	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	hLH	_	INTJ	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	prove	_	VERB	_	VerbForm=Inf	_	_	_	_
8	useful	_	ADJ	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	marker	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	CML	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	SCONJ	_	_	_	_	_	_
15	monitoring	_	VERB	_	VerbForm=Ger	_	_	_	_
16	residual	_	ADJ	_	Degree=Pos	_	_	_	_
17	disease	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011215	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	lowered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	during	_	ADP	_	_	_	_	_	_
16	aging	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	young	_	ADJ	_	Degree=Pos	_	_	_	_
19	individuals	_	NOUN	_	Number=Plur	_	_	_	_
20	following	_	VERB	_	VerbForm=Ger	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	variety	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
27	including	_	VERB	_	VerbForm=Ger	_	_	_	_
28	anti-CD3	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
31	myristate	_	NOUN	_	Number=Sing	_	_	_	_
32	acetate	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	PMA	_	PROPN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	tumor	_	NOUN	_	Number=Sing	_	_	_	_
39	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
40	factor	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	alpha	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	TNF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	alpha	_	NOUN	_	Number=Sing	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	older	_	ADJ	_	Degree=Cmp	_	_	_	_
9	individuals	_	NOUN	_	Number=Plur	_	_	_	_
10	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	significant	_	ADJ	_	Degree=Pos	_	_	_	_
13	reduction	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	same	_	ADJ	_	Degree=Pos	_	_	_	_
26	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	age	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	related	_	ADJ	_	Degree=Pos	_	_	_	_
5	decline	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	kappa	_	PROPN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	could	_	AUX	_	VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	attributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	alteration	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	composition	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	subunits	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	p50	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	p65	_	NOUN	_	Number=Sing	_	_	_	_
27	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	predominant	_	ADJ	_	Degree=Pos	_	_	_	_
33	subunits	_	NOUN	_	Number=Plur	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	T	_	PROPN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	from	_	ADP	_	_	_	_	_	_
43	young	_	ADJ	_	Degree=Pos	_	_	_	_
44	as	_	ADV	_	_	_	_	_	_
45	well	_	ADV	_	Degree=Pos	_	_	_	_
46	as	_	ADP	_	_	_	_	_	_
47	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
48	donors	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	similar	_	ADJ	_	Degree=Pos	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	kappa	_	PROPN	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cytosols	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	unactivated	_	ADJ	_	Degree=Pos	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	both	_	DET	_	_	_	_	_	_
20	young	_	ADJ	_	Degree=Pos	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
23	donors	_	NOUN	_	Number=Plur	_	_	_	_
24	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	precursor	_	NOUN	_	Number=Sing	_	_	_	_
27	levels	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	unaltered	_	ADJ	_	Degree=Pos	_	_	_	_
34	during	_	ADP	_	_	_	_	_	_
35	aging	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	age	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	decline	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	elderly	_	ADJ	_	Degree=Pos	_	_	_	_
23	individuals	_	NOUN	_	Number=Plur	_	_	_	_
24	may	_	AUX	_	VerbForm=Fin	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	attributable	_	ADJ	_	Degree=Pos	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	regulation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
35	kappa	_	VERB	_	Number=Sing	_	_	_	_
36	B	_	PROPN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	may	_	AUX	_	VerbForm=Fin	_	_	_	_
40	play	_	VERB	_	VerbForm=Inf	_	_	_	_
41	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	important	_	ADJ	_	Degree=Pos	_	_	_	_
43	role	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	immune	_	ADJ	_	Degree=Pos	_	_	_	_
46	dysregulation	_	NOUN	_	Number=Sing	_	_	_	_
47	accompanying	_	VERB	_	VerbForm=Ger	_	_	_	_
48	aging	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011219	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Ah	_	NOUN	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	TCDD	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	high	_	ADJ	_	Degree=Pos	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	Ah	_	NOUN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	TCDD	_	NOUN	_	Number=Sing	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
19	blood	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	individuals	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	paper	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	blood	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	first	_	ADV	_	_	_	_	_	_
15	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	fractions	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	nucleated	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	revealing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	predominant	_	ADJ	_	Degree=Pos	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	Ah	_	NOUN	_	Number=Sing	_	_	_	_
28	receptor	_	NOUN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
33	fraction	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Then	_	ADV	_	PronType=Dem	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	AhR	_	PROPN	_	Number=Sing	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	various	_	ADJ	_	Degree=Pos	_	_	_	_
10	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	lines	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	together	_	ADV	_	_	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	Arnt	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	P450IA1	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	AhR	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	at	_	ADP	_	_	_	_	_	_
5	high	_	ADJ	_	Degree=Pos	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	monocytoid	_	PROPN	_	Number=Sing	_	_	_	_
9	U937	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	THP1	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	HEL	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	S	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	moderate	_	ADJ	_	Degree=Pos	_	_	_	_
22	levels	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	HL60	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	erythroblastic	_	ADJ	_	Degree=Pos	_	_	_	_
29	HEL	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	MOLT4	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	T	_	X	_	NumType=Card	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	BALL1	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	B	_	NOUN	_	NumType=Card	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	nor	_	CCONJ	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	K562	_	NUM	_	Number=Sing	_	_	_	_
25	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	AhR	_	NOUN	_	Number=Sing	_	_	_	_
8	during	_	ADP	_	_	_	_	_	_
9	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	HL60	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	HEL	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	HL60	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	toward	_	ADP	_	_	_	_	_	_
8	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	incubation	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
15	ester	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	showing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	5	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	fold	_	NOUN	_	Number=Sing	_	_	_	_
25	increase	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	AhR	_	NOUN	_	Number=Sing	_	_	_	_
28	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	incubation	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	SCONJ	_	_	_	_	_	_
4	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
5	growth	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	alpha,25	_	NUM	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_

1	D3	_	PROPN	_	Number=Sing	_	_	_	_
2	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	7	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	fold	_	NOUN	_	Number=Sing	_	_	_	_
11	increase	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	AhR	_	PROPN	_	Number=Sing	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	HEL	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	similar	_	ADJ	_	Degree=Pos	_	_	_	_
8	elevation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	AhR	_	PROPN	_	Number=Sing	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	level	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	when	_	ADV	_	PronType=Rel	_	_	_	_
15	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
16	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	differentiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	toward	_	ADP	_	_	_	_	_	_
19	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
25	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	inducers	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	but	_	CCONJ	_	_	_	_	_	_
29	little	_	ADJ	_	Degree=Pos	_	_	_	_
30	change	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
34	level	_	NOUN	_	Number=Sing	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	when	_	ADV	_	PronType=Int	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
42	to	_	PART	_	_	_	_	_	_
43	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
44	into	_	ADP	_	_	_	_	_	_
45	other	_	ADJ	_	Degree=Pos	_	_	_	_
46	cell	_	NOUN	_	Number=Sing	_	_	_	_
47	types	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
5	HL60	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	methylcholanthrene	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	ligand	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	AhR	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	P450IA1	_	NOUN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	AhR	_	PROPN	_	Number=Sing	_	_	_	_
8	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	significantly	_	ADV	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	during	_	ADP	_	_	_	_	_	_
13	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	differentiated	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	xenobiotics	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	AhR	_	PROPN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	play	_	VERB	_	VerbForm=Inf	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	function	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	also	_	ADV	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	eventual	_	ADJ	_	Degree=Pos	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	environmental	_	ADJ	_	Degree=Pos	_	_	_	_
24	carcinogens	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011228	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	8	_	NUM	_	NumType=Card	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	uses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	CD28	_	NOUN	_	Number=Sing	_	_	_	_
13	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	pathway	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	8	_	NUM	_	NumType=Card	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	potent	_	ADJ	_	Degree=Pos	_	_	_	_
7	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
11	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
19	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	variety	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	types	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	including	_	VERB	_	VerbForm=Ger	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CD28	_	NOUN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	surface	_	NOUN	_	Number=Sing	_	_	_	_
7	molecule	_	NOUN	_	Number=Sing	_	_	_	_
8	delivers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	signals	_	NOUN	_	Number=Plur	_	_	_	_
11	essential	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	via	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	conserved	_	VERB	_	Degree=Pos	_	_	_	_
22	sequence	_	NOUN	_	Number=Sing	_	_	_	_
23	element	_	NOUN	_	Number=Sing	_	_	_	_
24	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	several	_	ADJ	_	Degree=Pos	_	_	_	_
30	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
31	genes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Anti-CD28-stimulated	_	PROPN	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	significant	_	ADJ	_	Degree=Pos	_	_	_	_
5	amounts	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	8	_	NUM	_	NumType=Card	_	_	_	_
10	;	_	PUNCT	_	_	_	_	_	_
11	additionally	_	ADV	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	anti-CD28	_	PROPN	_	Number=Sing	_	_	_	_

1	Abs	_	NOUN	_	Number=Sing	_	_	_	_
2	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	8	_	NUM	_	NumType=Card	_	_	_	_
11	secretion	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Sequence	_	NOUN	_	Number=Sing	_	_	_	_
2	homology	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	single	_	ADJ	_	Degree=Pos	_	_	_	_
5	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
6	mutations	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	anti-CD28	_	NOUN	_	Number=Sing	_	_	_	_

1	Ab	_	PROPN	_	_	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	like	_	ADP	_	Degree=Pos	_	_	_	_
13	sequence	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	8	_	NUM	_	NumType=Card	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	functioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	CD28	_	PROPN	_	Number=Sing	_	_	_	_
27	response	_	NOUN	_	Number=Sing	_	_	_	_
28	element	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_

1	A	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	but	_	CCONJ	_	_	_	_	_	_
4	not	_	ADV	_	_	_	_	_	_
5	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	8	_	NUM	_	NumType=Card	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	achieved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	anti-CD28	_	ADJ	_	Degree=Pos	_	_	_	_
21	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	involvement	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	CD28	_	NOUN	_	Number=Sing	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	8	_	NUM	_	NumType=Card	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	T	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
22	new	_	ADJ	_	Degree=Pos	_	_	_	_
23	insights	_	NOUN	_	Number=Plur	_	_	_	_
24	into	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	persistence	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	immune	_	ADJ	_	Degree=Pos	_	_	_	_
31	disorders	_	NOUN	_	Number=Plur	_	_	_	_
32	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	levels	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	SYM	_	_	_	_	_	_
39	8	_	NUM	_	NumType=Card	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	such	_	ADJ	_	Degree=Pos	_	_	_	_
42	as	_	ADP	_	_	_	_	_	_
43	psoriasis	_	NOUN	_	Number=Sing	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	rheumatoid	_	VERB	_	Number=Sing	_	_	_	_
46	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011230	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Genes	_	NOUN	_	Number=Plur	_	_	_	_
2	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
3	general	_	ADJ	_	Degree=Pos	_	_	_	_
4	initiation	_	NOUN	_	Number=Sing	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	RNA	_	PROPN	_	Number=Sing	_	_	_	_
8	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
9	II	_	NUM	_	NumType=Card	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	dispersed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	genome	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	General	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	accurate	_	ADJ	_	Degree=Pos	_	_	_	_
8	initiation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	RNA	_	PROPN	_	Number=Sing	_	_	_	_
13	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
14	II	_	NUM	_	NumType=Card	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	cDNAs	_	NOUN	_	Number=Plur	_	_	_	_
3	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
4	subunits	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	sequenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	fluorescence	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	situ	_	NOUN	_	Number=Sing	_	_	_	_
5	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	FISH	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	here	_	ADV	_	PronType=Dem	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	TATA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	box	_	NOUN	_	Number=Sing	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	TBP	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	TFIIB	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	TFIIE	_	PROPN	_	Number=Sing	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	TFIIE	_	PROPN	_	Number=Sing	_	_	_	_
33	beta	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	RAP30	_	PROPN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	RAP74	_	PROPN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	62	_	NUM	_	NumType=Card	_	_	_	_
41	kDa	_	NOUN	_	Number=Sing	_	_	_	_
42	subunit	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	TFIIH	_	PROPN	_	Number=Sing	_	_	_	_
46	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
47	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	at	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	human	_	ADJ	_	Degree=Pos	_	_	_	_
51	chromosomal	_	NOUN	_	Number=Sing	_	_	_	_
52	bands	_	NOUN	_	Number=Plur	_	_	_	_
53	6q26	_	NUM	_	NumType=Card	_	_	_	_
54	-	_	SYM	_	_	_	_	_	_
55	27	_	NUM	_	NumType=Card	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	1p21-22	_	NUM	_	NumType=Card	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	3q21-24	_	NUM	_	NumType=Card	_	_	_	_
60	,	_	PUNCT	_	_	_	_	_	_
61	8p12	_	NUM	_	NumType=Card	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	13q14	_	NUM	_	NumType=Card	_	_	_	_
64	,	_	PUNCT	_	_	_	_	_	_
65	19p13.3	_	NUM	_	NumType=Card	_	_	_	_
66	and	_	CCONJ	_	_	_	_	_	_
67	11p14-15.1	_	NUM	_	NumType=Card	_	_	_	_
68	,	_	PUNCT	_	_	_	_	_	_
69	respectively	_	ADV	_	_	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	dispersed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	localization	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	group	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	functionally	_	ADV	_	_	_	_	_	_
9	related	_	ADJ	_	Degree=Pos	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	insights	_	NOUN	_	Number=Plur	_	_	_	_
13	into	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
16	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	genome	_	NOUN	_	Number=Sing	_	_	_	_
20	evolution	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	possible	_	ADJ	_	Degree=Pos	_	_	_	_
24	involvement	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	diseases	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011239	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	sexual	_	ADJ	_	Degree=Pos	_	_	_	_
7	dimorphism	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	autoimmunity	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	sexual	_	ADJ	_	Degree=Pos	_	_	_	_
3	difference	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	incidence	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	autoimmune	_	NOUN	_	Number=Sing	_	_	_	_
9	diseases	_	NOUN	_	Number=Plur	_	_	_	_
10	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	remained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	enigma	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	many	_	ADJ	_	Degree=Pos	_	_	_	_
16	years	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	examination	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	autoimmunity	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
11	mice	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	evidence	_	NOUN	_	Number=Sing	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	further	_	ADV	_	_	_	_	_	_
18	implicating	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
21	interferon	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	gamma	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	etiology	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	autoimmunity	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Sex	_	NOUN	_	Number=Sing	_	_	_	_
2	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
3	regulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	production	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	molecule	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	as	_	ADV	_	_	_	_	_	_
12	well	_	ADV	_	Degree=Pos	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	other	_	ADJ	_	Degree=Pos	_	_	_	_
15	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	help	_	VERB	_	VerbForm=Inf	_	_	_	_
19	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	gender	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	differences	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	immune	_	NOUN	_	Number=Sing	_	_	_	_
28	system	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	including	_	VERB	_	VerbForm=Ger	_	_	_	_
31	autoimmunity	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011254	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Alternative	_	ADJ	_	Degree=Pos	_	_	_	_
2	splicing	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	RNA	_	PROPN	_	Number=Sing	_	_	_	_
5	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
6	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	murine	_	NOUN	_	Number=Sing	_	_	_	_
10	p105	_	NUM	_	Number=Sing	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	generates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	gamma	_	NOUN	_	Number=Sing	_	_	_	_
21	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	different	_	ADJ	_	Degree=Pos	_	_	_	_
24	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
25	activities	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	105	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kDa	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	p105	_	NUM	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	precursor	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	p50	_	NUM	_	Number=Sing	_	_	_	_
16	subunit	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	also	_	ADV	_	_	_	_	_	_
25	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	p70	_	NOUN	_	Number=Sing	_	_	_	_
28	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
29	kappa	_	VERB	_	Number=Sing	_	_	_	_
30	B	_	PROPN	_	Number=Sing	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
34	kappa	_	VERB	_	Number=Sing	_	_	_	_
35	B	_	PROPN	_	Number=Sing	_	_	_	_
36	gamma	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	which	_	PRON	_	PronType=Rel	_	_	_	_
39	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	identical	_	ADJ	_	Degree=Pos	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	C	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	terminal	_	NOUN	_	Number=Sing	_	_	_	_
46	607	_	NUM	_	NumType=Card	_	_	_	_
47	amino	_	NOUN	_	Number=Sing	_	_	_	_
48	acids	_	NOUN	_	Number=Plur	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	p105	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
6	RNA	_	PROPN	_	Number=Sing	_	_	_	_
7	splicing	_	NOUN	_	Number=Sing	_	_	_	_
8	generates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	kappa	_	VERB	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	gamma	_	NOUN	_	Number=Sing	_	_	_	_
13	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	properties	_	NOUN	_	Number=Plur	_	_	_	_
16	different	_	ADJ	_	Degree=Pos	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	p70	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	63	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kDa	_	NOUN	_	Number=Sing	_	_	_	_
5	isoform	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	kappa	_	VERB	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	lacks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	59	_	NUM	_	NumType=Card	_	_	_	_
18	amino	_	NOUN	_	Number=Sing	_	_	_	_
19	acids	_	NOUN	_	Number=Plur	_	_	_	_
20	C	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	terminal	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	ankyrin	_	VERB	_	Number=Sing	_	_	_	_
25	repeat	_	NOUN	_	Number=Sing	_	_	_	_
26	7	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	novel	_	NOUN	_	Number=Sing	_	_	_	_
31	35	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	amino	_	NOUN	_	Number=Sing	_	_	_	_
34	acid	_	NOUN	_	Number=Sing	_	_	_	_
35	C	_	PROPN	_	Number=Sing	_	_	_	_
36	terminus	_	NOUN	_	Number=Sing	_	_	_	_
37	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
41	reading	_	NOUN	_	Number=Sing	_	_	_	_
42	frame	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	p105	_	NOUN	_	NumType=Card	_	_	_	_
46	gene	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	55	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kDa	_	NOUN	_	Number=Sing	_	_	_	_
5	isoform	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	kappa	_	VERB	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	gamma	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	lacks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	190	_	NUM	_	NumType=Card	_	_	_	_
17	C	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	terminal	_	ADJ	_	Number=Sing	_	_	_	_
20	amino	_	NOUN	_	Number=Sing	_	_	_	_
21	acids	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	p70I	_	NOUN	_	Number=Sing	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	gamma	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	p70I	_	NOUN	_	Number=Sing	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	VERB	_	Number=Sing	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	gamma	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	both	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	nucleus	_	ADJ	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	whereas	_	SCONJ	_	_	_	_	_	_
31	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
32	kappa	_	VERB	_	Number=Sing	_	_	_	_
33	B	_	PROPN	_	Number=Sing	_	_	_	_
34	gamma	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	predominantly	_	ADV	_	_	_	_	_	_
39	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	kappa	_	VERB	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	gamma	_	NOUN	_	Number=Sing	_	_	_	_
6	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	display	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	differences	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	specificity	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	affinity	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	Rel	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	p70I	_	NOUN	_	Number=Sing	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	gamma	_	NOUN	_	Number=Sing	_	_	_	_
6	inhibits	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	p50	_	NUM	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	p65	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	both	_	CCONJ	_	_	_	_	_	_
25	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
26	kappa	_	VERB	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	gamma	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
33	kappa	_	VERB	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	gamma	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	specific	_	ADJ	_	Degree=Pos	_	_	_	_
40	for	_	ADP	_	_	_	_	_	_
41	p50	_	NUM	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
44	different	_	ADJ	_	Degree=Pos	_	_	_	_
45	affinities	_	NOUN	_	Number=Plur	_	_	_	_
46	for	_	ADP	_	_	_	_	_	_
47	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
48	subunit	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	absence	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	kappa	_	VERB	_	Number=Sing	_	_	_	_
6	B	_	PROPN	_	Number=Sing	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	kappa	_	VERB	_	Number=Sing	_	_	_	_
13	B	_	PROPN	_	Number=Sing	_	_	_	_
14	gamma	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
24	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
25	modulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	p70I	_	NOUN	_	Number=Sing	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	gamma	_	NOUN	_	Number=Sing	_	_	_	_
30	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
31	activity	_	NOUN	_	Number=Sing	_	_	_	_
32	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	that	_	SCONJ	_	_	_	_	_	_
34	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
35	RNA	_	PROPN	_	Number=Sing	_	_	_	_
36	splicing	_	NOUN	_	Number=Sing	_	_	_	_
37	may	_	AUX	_	VerbForm=Fin	_	_	_	_
38	be	_	AUX	_	VerbForm=Inf	_	_	_	_
39	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	to	_	PART	_	_	_	_	_	_
41	generate	_	VERB	_	VerbForm=Inf	_	_	_	_
42	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
43	kappa	_	VERB	_	Number=Sing	_	_	_	_
44	B	_	NOUN	_	Number=Sing	_	_	_	_
45	gamma	_	NOUN	_	Number=Sing	_	_	_	_
46	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
47	that	_	PRON	_	PronType=Rel	_	_	_	_
48	respond	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
49	differently	_	ADV	_	_	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
52	signals	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011255	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	2A	_	NUM	_	Number=Sing	_	_	_	_
22	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	2A	_	NUM	_	Number=Sing	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	important	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
10	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	functions	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
16	state	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	substrates	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
12	acid	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	calyculin	_	VERB	_	Number=Sing	_	_	_	_
15	A	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
23	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
26	production	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	beta	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
4	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	primarily	_	ADV	_	_	_	_	_	_
10	because	_	ADP	_	_	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	increase	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	rate	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	caused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	activities	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	including	_	VERB	_	VerbForm=Ger	_	_	_	_
20	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	AP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
30	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Okadaic	_	PROPN	_	Number=Sing	_	_	_	_
2	acid	_	NOUN	_	Number=Sing	_	_	_	_
3	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	precursor	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	mature	_	ADJ	_	Degree=Pos	_	_	_	_
15	forms	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	secretion	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	processing	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	secretion	_	NOUN	_	Number=Sing	_	_	_	_
6	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	convertase	_	NOUN	_	Number=Sing	_	_	_	_
16	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
17	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	production	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
11	acid	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	more	_	ADV	_	_	_	_	_	_
14	modest	_	ADJ	_	Degree=Pos	_	_	_	_
15	than	_	ADP	_	_	_	_	_	_
16	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	beta	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	precursor	_	NOUN	_	Number=Sing	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	2A	_	NUM	_	Number=Sing	_	_	_	_
10	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
11	exert	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
13	effects	_	NOUN	_	Number=Plur	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
24	two	_	NUM	_	NumType=Card	_	_	_	_
25	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
26	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	important	_	ADJ	_	Degree=Pos	_	_	_	_
28	roles	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	SCONJ	_	_	_	_	_	_
30	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
31	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	production	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011257	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Structure	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	function	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	antigen	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	:	_	PUNCT	_	_	_	_	_	_
15	evidence	_	NOUN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	role	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	not	_	ADV	_	_	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	c	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	Myb	_	PROPN	_	Number=Sing	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
31	lineage	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	specific	_	ADJ	_	Degree=Pos	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	antigen	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	MNDA	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	specifically	_	ADV	_	_	_	_	_	_
13	in	_	SCONJ	_	_	_	_	_	_
14	maturing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	lineage	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Epitope	_	PROPN	_	Number=Sing	_	_	_	_
2	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	confirm	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	strict	_	ADJ	_	Degree=Pos	_	_	_	_
9	lineage	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	stage	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	MNDA	_	PROPN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	bone	_	NOUN	_	Number=Sing	_	_	_	_
20	marrow	_	NOUN	_	Number=Sing	_	_	_	_
21	as	_	ADV	_	_	_	_	_	_
22	well	_	ADV	_	Degree=Pos	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	other	_	ADJ	_	Degree=Pos	_	_	_	_
26	paraffin	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	embedded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	fixed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	tissues	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	1	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kb	_	NOUN	_	Number=Sing	_	_	_	_
5	region	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	5	_	NUM	_	NumType=Card	_	_	_	_
12	'	_	PUNCT	_	_	_	_	_	_
13	flanking	_	NOUN	_	Degree=Pos	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	earlier	_	ADV	_	Degree=Cmp	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
20	functional	_	ADJ	_	Degree=Pos	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	specifically	_	ADV	_	_	_	_	_	_
26	demethylated	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	SCONJ	_	_	_	_	_	_
28	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	contrast	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	null	_	ADJ	_	Degree=Pos	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kb	_	NOUN	_	Number=Sing	_	_	_	_
10	fragment	_	NOUN	_	Number=Sing	_	_	_	_
11	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
13	reporter	_	NOUN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	MNDA	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	than	_	ADP	_	_	_	_	_	_
22	non	_	X	_	_	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	specific	_	ADJ	_	Degree=Pos	_	_	_	_
31	differences	_	NOUN	_	Number=Plur	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	consensus	_	NOUN	_	Number=Sing	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	myeloid	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	including	_	VERB	_	VerbForm=Ger	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	PU.	_	NOUN	_	Number=Sing	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	consensus	_	NOUN	_	Number=Sing	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	near	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	major	_	ADJ	_	Degree=Pos	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	start	_	NOUN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	cluster	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	c	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	Myb	_	NOUN	_	Number=Sing	_	_	_	_
33	sites	_	NOUN	_	Number=Plur	_	_	_	_
34	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	several	_	ADJ	_	Degree=Pos	_	_	_	_
36	hundred	_	NUM	_	NumType=Card	_	_	_	_
37	bases	_	NOUN	_	Number=Plur	_	_	_	_
38	upstream	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
41	region	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	deletion	_	NOUN	_	Number=Sing	_	_	_	_
6	mutants	_	NOUN	_	Number=Plur	_	_	_	_
7	localized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	nearly	_	ADV	_	_	_	_	_	_
9	all	_	DET	_	_	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	promoter	_	ADJ	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	short	_	ADJ	_	Degree=Pos	_	_	_	_
17	region	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	-	_	SYM	_	_	_	_	_	_
20	73	_	NUM	_	NumType=Card	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	-	_	SYM	_	_	_	_	_	_
23	16	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	include	_	VERB	_	VerbForm=Inf	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	cluster	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	c	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	Myb	_	NOUN	_	Number=Sing	_	_	_	_
35	sites	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	4	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	bp	_	NOUN	_	Number=Sing	_	_	_	_
5	mutation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	core	_	NOUN	_	Number=Sing	_	_	_	_
9	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
10	consensus	_	NOUN	_	Number=Sing	_	_	_	_
11	element	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	GC	_	NOUN	_	Number=Sing	_	_	_	_
14	box	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	20	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	overall	_	ADJ	_	Degree=Pos	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kb	_	NOUN	_	Number=Sing	_	_	_	_
29	fragment	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	significantly	_	ADV	_	_	_	_	_	_
9	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Only	_	ADV	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	small	_	ADJ	_	Degree=Pos	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	-	_	SYM	_	_	_	_	_	_
7	35	_	NUM	_	NumType=Card	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_
10	22	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	including	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
15	element	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	start	_	NOUN	_	Number=Sing	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	not	_	ADV	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	footprinted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	4	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	bp	_	NOUN	_	Number=Sing	_	_	_	_
5	mutation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	core	_	NOUN	_	Number=Sing	_	_	_	_
9	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
10	consensus	_	NOUN	_	Number=Sing	_	_	_	_
11	element	_	NOUN	_	Number=Sing	_	_	_	_
12	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	antibody	_	NOUN	_	Number=Sing	_	_	_	_
20	super	_	ADJ	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	shift	_	NOUN	_	Number=Sing	_	_	_	_
23	reaction	_	NOUN	_	Number=Sing	_	_	_	_
24	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	one	_	NUM	_	NumType=Card	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	factors	_	NOUN	_	Number=Plur	_	_	_	_
32	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	consensus	_	NOUN	_	Number=Sing	_	_	_	_
35	site	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
3	site	_	NOUN	_	Number=Sing	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	co	_	AUX	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	localizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	DNase	_	NOUN	_	Number=Sing	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	hypersensitive	_	VERB	_	Degree=Pos	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	methylation	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
9	structure	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	contribute	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	highly	_	ADV	_	_	_	_	_	_
21	restricted	_	VERB	_	Degree=Pos	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
26	lineage	_	NOUN	_	Number=Sing	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011258	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	cloning	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	FKHRL1P2	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	member	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	developmentally	_	ADV	_	_	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	fork	_	NOUN	_	Number=Sing	_	_	_	_
13	head	_	NOUN	_	Number=Sing	_	_	_	_
14	domain	_	NOUN	_	Number=Sing	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	family	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	fork	_	NOUN	_	Number=Sing	_	_	_	_
9	head	_	NOUN	_	Number=Sing	_	_	_	_
10	domain	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	helper	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	cloned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	characterized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	fork	_	NOUN	_	Number=Sing	_	_	_	_
7	head	_	NOUN	_	Number=Sing	_	_	_	_
8	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	helper	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	using	_	VERB	_	VerbForm=Ger	_	_	_	_
16	differential	_	NOUN	_	Number=Sing	_	_	_	_
17	display	_	NOUN	_	Number=Sing	_	_	_	_
18	RT	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	PCR	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
3	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	546	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	nucleotide	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	nt	_	ADV	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	open	_	ADJ	_	Degree=Pos	_	_	_	_
12	reading	_	NOUN	_	VerbForm=Ger	_	_	_	_
13	frame	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	ORF	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	that	_	DET	_	PronType=Rel	_	_	_	_
18	codes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	carboxyl	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	terminal	_	NOUN	_	Number=Sing	_	_	_	_
24	180	_	NUM	_	NumType=Card	_	_	_	_
25	amino	_	NOUN	_	Number=Sing	_	_	_	_
26	acids	_	NOUN	_	Number=Plur	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	aa	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	recently	_	ADV	_	_	_	_	_	_
33	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	fkhrl1	_	ADJ	_	Degree=Pos	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	ORF	_	NOUN	_	Number=Sing	_	_	_	_
3	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	characteristic	_	ADJ	_	Degree=Pos	_	_	_	_
8	DNA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	domain	_	NOUN	_	Number=Sing	_	_	_	_
12	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	members	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	forkhead	_	NOUN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	family	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	vitro	_	NOUN	_	Number=Sing	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	translation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
10	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	approximately	_	ADV	_	_	_	_	_	_
15	20	_	NUM	_	NumType=Card	_	_	_	_
16	kDa	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	specifically	_	ADV	_	_	_	_	_	_
7	immunoprecipitated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	vitro	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	20	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kDa	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	antibody	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	70	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kDa	_	NOUN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	corresponding	_	VERB	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	size	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
19	predicted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	fkhrl1	_	ADJ	_	Degree=Pos	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	product	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	fkhrl1	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	elevated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	helper	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	comparison	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	PHA	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	characterization	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	FKHRL1	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
7	related	_	ADJ	_	Degree=Pos	_	_	_	_
8	family	_	NOUN	_	Number=Sing	_	_	_	_
9	members	_	NOUN	_	Number=Plur	_	_	_	_
10	should	_	AUX	_	VerbForm=Fin	_	_	_	_
11	shed	_	VERB	_	VerbForm=Inf	_	_	_	_
12	light	_	NOUN	_	Number=Sing	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
16	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	fork	_	NOUN	_	Number=Sing	_	_	_	_
20	head	_	NOUN	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	subfamily	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	role	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	T	_	PROPN	_	Number=Sing	_	_	_	_
28	helper	_	NOUN	_	Number=Sing	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	regulation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	growth	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011260	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	promoter	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	CD19	_	PROPN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	target	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	BSAP	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CD19	_	PROPN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	surface	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	all	_	DET	_	_	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	exception	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	terminally	_	ADV	_	_	_	_	_	_
20	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
21	plasma	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	signal	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	transducing	_	NOUN	_	VerbForm=Ger	_	_	_	_
32	receptor	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	control	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	complete	_	ADJ	_	Degree=Pos	_	_	_	_
5	correlation	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	pattern	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	CD19	_	PROPN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	BSAP	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	large	_	ADJ	_	Degree=Pos	_	_	_	_
27	panel	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	lines	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	CD19	_	PROPN	_	Number=Sing	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	several	_	ADJ	_	Degree=Pos	_	_	_	_
11	BSAP	_	NOUN	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	sites	_	NOUN	_	Number=Plur	_	_	_	_
15	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	mapped	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	vitro	_	NOUN	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	DNA	_	PROPN	_	Number=Sing	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	studies	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	particular	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	high	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	affinity	_	NOUN	_	Number=Sing	_	_	_	_
8	BSAP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	instead	_	ADV	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	TATA	_	PROPN	_	Number=Sing	_	_	_	_
16	sequence	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	30	_	NUM	_	NumType=Card	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	region	_	NOUN	_	Number=Sing	_	_	_	_
25	upstream	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	cluster	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	heterogeneous	_	ADJ	_	Degree=Pos	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	start	_	NOUN	_	Number=Sing	_	_	_	_
33	sites	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	site	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	occupied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	BSAP	_	PROPN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vivo	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	CD19	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	line	_	NOUN	_	Number=Sing	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	plasma	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	high	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	affinity	_	NOUN	_	Number=Sing	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	conserved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	promoters	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	mouse	_	NOUN	_	Number=Sing	_	_	_	_
17	CD19	_	PROPN	_	Number=Sing	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	furthermore	_	ADV	_	_	_	_	_	_
22	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	confer	_	VERB	_	VerbForm=Inf	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	specificity	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	beta	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	globin	_	ADJ	_	Degree=Pos	_	_	_	_
34	reporter	_	NOUN	_	Number=Sing	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	transient	_	ADJ	_	Degree=Pos	_	_	_	_
38	transfection	_	NOUN	_	Number=Sing	_	_	_	_
39	experiments	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	BSAP	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	only	_	ADJ	_	Degree=Pos	_	_	_	_
11	abundant	_	ADJ	_	Degree=Pos	_	_	_	_
12	DNA	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	binding	_	VERB	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	extracts	_	NOUN	_	Number=Plur	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	CD19	_	PROPN	_	Number=Sing	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	evidence	_	NOUN	_	Number=Sing	_	_	_	_
5	strongly	_	ADV	_	_	_	_	_	_
6	implicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	BSAP	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	CD19	_	PROPN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011261	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Simple	_	ADJ	_	Degree=Pos	_	_	_	_
2	derivation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TFIID	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	RNA	_	NOUN	_	Number=Sing	_	_	_	_
8	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
9	II	_	NUM	_	NumType=Card	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	systems	_	NOUN	_	Number=Plur	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	Schizosaccharomyces	_	PROPN	_	Number=Plur	_	_	_	_
14	pombe	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	other	_	ADJ	_	Degree=Pos	_	_	_	_
17	organisms	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	factors	_	NOUN	_	Number=Plur	_	_	_	_
21	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Resolution	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	whole	_	ADJ	_	Degree=Pos	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	extract	_	NOUN	_	Number=Sing	_	_	_	_
6	through	_	ADP	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	chromatographic	_	ADJ	_	Degree=Pos	_	_	_	_
9	steps	_	NOUN	_	Number=Plur	_	_	_	_
10	yields	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	single	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	fraction	_	NOUN	_	Number=Sing	_	_	_	_
15	requiring	_	VERB	_	VerbForm=Ger	_	_	_	_
16	only	_	ADV	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	addition	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	TFIID	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	initiation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	at	_	ADP	_	_	_	_	_	_
27	RNA	_	PROPN	_	Number=Sing	_	_	_	_
28	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
29	II	_	NUM	_	NumType=Card	_	_	_	_
30	promoters	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	approach	_	NOUN	_	Number=Sing	_	_	_	_
3	allows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	convenient	_	ADJ	_	Degree=Pos	_	_	_	_
6	generation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	RNA	_	PROPN	_	Number=Sing	_	_	_	_
9	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
10	II	_	NUM	_	NumType=Card	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	systems	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	Saccharomyces	_	PROPN	_	Number=Sing	_	_	_	_
15	cerevisiae	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	Schizosaccharomyces	_	NOUN	_	Number=Plur	_	_	_	_
22	pombe	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	TFIIDs	_	NOUN	_	Number=Plur	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	all	_	DET	_	_	_	_	_	_
4	three	_	NUM	_	NumType=Card	_	_	_	_
5	organisms	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	interchangeable	_	ADJ	_	Degree=Pos	_	_	_	_
8	among	_	ADP	_	_	_	_	_	_
9	all	_	DET	_	_	_	_	_	_
10	three	_	NUM	_	NumType=Card	_	_	_	_
11	systems	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	S.	_	PROPN	_	Number=Sing	_	_	_	_
3	cerevisiae	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Sch	_	PROPN	_	Number=Sing	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	pombe	_	NOUN	_	Number=Sing	_	_	_	_
2	systems	_	NOUN	_	Number=Plur	_	_	_	_
3	support	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	acidic	_	ADJ	_	Degree=Pos	_	_	_	_
7	activator	_	NOUN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	provided	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	further	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	fraction	_	NOUN	_	Number=Sing	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	S.	_	PROPN	_	Number=Sing	_	_	_	_
17	cerevisiae	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	supplied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	further	_	ADJ	_	Degree=Pos	_	_	_	_
3	fraction	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	mediator	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	previously	_	ADV	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
18	component	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	addition	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	general	_	ADJ	_	Degree=Pos	_	_	_	_
23	initiation	_	NOUN	_	Number=Sing	_	_	_	_
24	factors	_	NOUN	_	Number=Plur	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	may	_	AUX	_	VerbForm=Fin	_	_	_	_
27	facilitate	_	VERB	_	VerbForm=Inf	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	response	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	acidic	_	VERB	_	Degree=Pos	_	_	_	_
32	activators	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011269	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Hypoxia	_	PROPN	_	Number=Sing	_	_	_	_
2	enhances	_	VERB	_	Number=Plur	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
6	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	:	_	PUNCT	_	_	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	metabolic	_	ADJ	_	Degree=Pos	_	_	_	_
13	acidosis	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	proteasomes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
3	molecule	_	NOUN	_	Number=Sing	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	important	_	ADJ	_	Degree=Pos	_	_	_	_
13	molecule	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	promotion	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	polymorphonuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
19	transendothelial	_	NOUN	_	Number=Sing	_	_	_	_
20	migration	_	NOUN	_	Number=Sing	_	_	_	_
21	during	_	ADP	_	_	_	_	_	_
22	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Coincident	_	ADJ	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	many	_	ADJ	_	Degree=Pos	_	_	_	_
4	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	diseases	_	NOUN	_	Number=Plur	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	tissue	_	ADJ	_	Degree=Pos	_	_	_	_
8	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	hypothesized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	combinations	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	differentially	_	ADV	_	_	_	_	_	_
13	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
17	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	X	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_
21	Human	_	ADJ	_	Degree=Pos	_	_	_	_
22	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	exposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	presence	_	NOUN	_	Number=Sing	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	absence	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	added	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	LPS	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	expression	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	functional	_	ADJ	_	Degree=Pos	_	_	_	_
45	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_
49	Although	_	SCONJ	_	_	_	_	_	_
50	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
51	alone	_	ADV	_	_	_	_	_	_
52	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
53	not	_	PART	_	_	_	_	_	_
54	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
55	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	1	_	NUM	_	NumType=Card	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
60	combination	_	NOUN	_	Number=Sing	_	_	_	_
61	of	_	ADP	_	_	_	_	_	_
62	LPS	_	NOUN	_	Number=Sing	_	_	_	_
63	and	_	CCONJ	_	_	_	_	_	_
64	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
65	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
66	(	_	PUNCT	_	_	_	_	_	_
67	3	_	NUM	_	NumType=Card	_	_	_	_
68	+/-	_	SYM	_	_	_	_	_	_
69	0.4	_	NUM	_	NumType=Card	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
72	over	_	ADP	_	_	_	_	_	_
73	normoxia	_	NOUN	_	Number=Sing	_	_	_	_
74	)	_	PUNCT	_	_	_	_	_	_
75	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
76	-	_	PUNCT	_	_	_	_	_	_
77	1	_	NUM	_	NumType=Card	_	_	_	_
78	expression	_	NOUN	_	Number=Sing	_	_	_	_
79	.	_	PUNCT	_	_	_	_	_	_

1	Combinations	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	LPS	_	PROPN	_	Number=Sing	_	_	_	_
6	significantly	_	ADV	_	_	_	_	_	_
7	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	such	_	ADJ	_	Degree=Pos	_	_	_	_
13	increases	_	NOUN	_	Number=Plur	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	addition	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	anti-ICAM	_	ADJ	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	antisense	_	ADJ	_	Number=Sing	_	_	_	_
25	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Hypoxic	_	ADJ	_	Degree=Pos	_	_	_	_
2	endothelia	_	NOUN	_	Number=Sing	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	NOUN	_	_	_	_	_	_
5	>	_	PUNCT	_	_	_	_	_	_

1	10	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	fold	_	NOUN	_	Number=Sing	_	_	_	_
4	increase	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	combinations	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	LPS	_	PROPN	_	Number=Sing	_	_	_	_
19	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
28	localization	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	p65	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	Rel	_	NOUN	_	Number=Sing	_	_	_	_
40	A	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	subunit	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Such	_	ADJ	_	Degree=Pos	_	_	_	_
2	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	evoked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	decreases	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	pH	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	endothelial	_	VERB	_	Degree=Pos	_	_	_	_
8	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
9	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	novel	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	proteasome	_	NOUN	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
16	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	induction	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011270	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	c	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	fos	_	NOUN	_	Number=Sing	_	_	_	_
6	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	IFN	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	Philadelphia	_	PROPN	_	Number=Sing	_	_	_	_
14	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
15	positive	_	ADJ	_	Degree=Pos	_	_	_	_
16	chronic	_	ADJ	_	Number=Sing	_	_	_	_
17	myelogenous	_	ADJ	_	Degree=Pos	_	_	_	_
18	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	evaluates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	i	_	X	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	p53	_	NOUN	_	Number=Sing	_	_	_	_
13	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	chronic	_	ADJ	_	Number=Sing	_	_	_	_
16	phase	_	NOUN	_	Number=Sing	_	_	_	_
17	CML	_	PROPN	_	Number=Sing	_	_	_	_
18	patients	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	ii	_	X	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	modulations	_	NOUN	_	Number=Plur	_	_	_	_
25	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	vivo	_	NOUN	_	Number=Sing	_	_	_	_
29	therapy	_	NOUN	_	Number=Sing	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	rIFN	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	2c	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
2	blood	_	NOUN	_	Number=Sing	_	_	_	_
3	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	pbmc	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	bone	_	VERB	_	Number=Sing	_	_	_	_
10	marrow	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	26	_	NUM	_	NumType=Card	_	_	_	_
14	patients	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	c	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	fos	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	c-myc	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	p53	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
28	bcr	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	abl	_	NOUN	_	Number=Sing	_	_	_	_
31	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
32	levels	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Results	_	NOUN	_	Number=Plur	_	_	_	_
2	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	i	_	X	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
8	c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	fos	_	ADP	_	Number=Sing	_	_	_	_
11	transcript	_	NOUN	_	Number=Sing	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	significantly	_	ADV	_	_	_	_	_	_
15	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	patients	_	NOUN	_	Number=Plur	_	_	_	_
18	subsequently	_	ADV	_	_	_	_	_	_
19	responding	_	VERB	_	VerbForm=Ger	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	IFN	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	therapy	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	p	_	NOUN	_	Number=Sing	_	_	_	_
27	<	_	PUNCT	_	_	_	_	_	_
28	0.01	_	NUM	_	NumType=Card	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	positively	_	ADV	_	_	_	_	_	_
32	correlated	_	VERB	_	Degree=Pos	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	proportion	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	r	_	NOUN	_	Number=Sing	_	_	_	_
40	=	_	SYM	_	_	_	_	_	_
41	0.6895	_	NUM	_	NumType=Card	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	p	_	NOUN	_	Number=Sing	_	_	_	_
44	<	_	PUNCT	_	_	_	_	_	_
45	0.01	_	NUM	_	NumType=Card	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	negatively	_	ADV	_	_	_	_	_	_
49	with	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	proportion	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	immature	_	ADJ	_	Degree=Pos	_	_	_	_
54	cells	_	NOUN	_	Number=Plur	_	_	_	_
55	(	_	PUNCT	_	_	_	_	_	_
56	r	_	NOUN	_	Number=Sing	_	_	_	_
57	=	_	SYM	_	_	_	_	_	_
58	-	_	SYM	_	_	_	_	_	_
59	0.568	_	NUM	_	NumType=Card	_	_	_	_
60	,	_	PUNCT	_	_	_	_	_	_
61	p	_	NOUN	_	Number=Sing	_	_	_	_
62	<	_	PUNCT	_	_	_	_	_	_
63	0.01	_	NUM	_	NumType=Card	_	_	_	_
64	)	_	PUNCT	_	_	_	_	_	_
65	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
66	in	_	ADP	_	_	_	_	_	_
67	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
68	pbmc	_	NOUN	_	Number=Sing	_	_	_	_
69	preparations	_	NOUN	_	Number=Plur	_	_	_	_
70	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
71	,	_	PUNCT	_	_	_	_	_	_
72	(	_	PUNCT	_	_	_	_	_	_
73	ii	_	X	_	_	_	_	_	_
74	)	_	PUNCT	_	_	_	_	_	_
75	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
76	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
77	levels	_	NOUN	_	Number=Plur	_	_	_	_
78	of	_	ADP	_	_	_	_	_	_
79	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
80	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
81	bcr	_	NOUN	_	Number=Sing	_	_	_	_
82	/	_	PUNCT	_	_	_	_	_	_
83	abl	_	NOUN	_	Number=Sing	_	_	_	_
84	,	_	PUNCT	_	_	_	_	_	_
85	c-myc	_	NOUN	_	Number=Sing	_	_	_	_
86	and	_	CCONJ	_	_	_	_	_	_
87	p53	_	NOUN	_	Number=Sing	_	_	_	_
88	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
89	positively	_	ADV	_	_	_	_	_	_
90	correlated	_	VERB	_	Degree=Pos	_	_	_	_
91	with	_	ADP	_	_	_	_	_	_
92	each	_	DET	_	_	_	_	_	_
93	other	_	ADJ	_	Degree=Pos	_	_	_	_
94	,	_	PUNCT	_	_	_	_	_	_
95	but	_	CCONJ	_	_	_	_	_	_
96	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
97	to	_	PART	_	_	_	_	_	_
98	relate	_	VERB	_	VerbForm=Inf	_	_	_	_
99	to	_	ADP	_	_	_	_	_	_
100	disease	_	NOUN	_	Number=Sing	_	_	_	_
101	parameters	_	NOUN	_	Number=Plur	_	_	_	_
102	,	_	PUNCT	_	_	_	_	_	_
103	and	_	CCONJ	_	_	_	_	_	_
104	(	_	PUNCT	_	_	_	_	_	_
105	iii	_	X	_	_	_	_	_	_
106	)	_	PUNCT	_	_	_	_	_	_
107	acute	_	NOUN	_	Degree=Pos	_	_	_	_
108	and	_	CCONJ	_	_	_	_	_	_
109	chronic	_	NOUN	_	Number=Sing	_	_	_	_
110	in	_	ADP	_	_	_	_	_	_
111	vivo	_	ADJ	_	Degree=Pos	_	_	_	_
112	exposure	_	NOUN	_	Number=Sing	_	_	_	_
113	to	_	ADP	_	_	_	_	_	_
114	IFN	_	PROPN	_	Number=Sing	_	_	_	_
115	-	_	PUNCT	_	_	_	_	_	_
116	alpha	_	NOUN	_	Number=Sing	_	_	_	_
117	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
118	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
119	by	_	ADP	_	_	_	_	_	_
120	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
121	of	_	ADP	_	_	_	_	_	_
122	c	_	NOUN	_	Number=Sing	_	_	_	_
123	-	_	PUNCT	_	_	_	_	_	_
124	fos	_	NOUN	_	Number=Sing	_	_	_	_
125	and	_	CCONJ	_	_	_	_	_	_
126	downregulation	_	NOUN	_	Number=Sing	_	_	_	_
127	of	_	ADP	_	_	_	_	_	_
128	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
129	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
130	levels	_	NOUN	_	Number=Plur	_	_	_	_
131	in	_	ADP	_	_	_	_	_	_
132	responder	_	NOUN	_	Number=Sing	_	_	_	_
133	patients	_	NOUN	_	Number=Plur	_	_	_	_
134	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011271	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	down	_	ADV	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	3	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	GM	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	CSF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
28	blood	_	NOUN	_	Number=Sing	_	_	_	_
29	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	product	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	T-helper	_	PROPN	_	Number=Sing	_	_	_	_
10	0	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	Th0	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	Th2	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	subset	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	originally	_	ADV	_	_	_	_	_	_
23	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	subsequently	_	ADV	_	_	_	_	_	_
34	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
35	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
38	IL	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	alpha	_	PROPN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	IL	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	beta	_	PROPN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	IL	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	6	_	NUM	_	NumType=Card	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	IL	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	8	_	NUM	_	NumType=Card	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	TNF	_	PROPN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	alpha	_	ADJ	_	Number=Sing	_	_	_	_
60	gene	_	NOUN	_	Number=Sing	_	_	_	_
61	expression	_	NOUN	_	Number=Sing	_	_	_	_
62	in	_	ADP	_	_	_	_	_	_
63	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
64	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
65	with	_	ADP	_	_	_	_	_	_
66	LPS	_	NOUN	_	Number=Sing	_	_	_	_
67	,	_	PUNCT	_	_	_	_	_	_
68	and	_	CCONJ	_	_	_	_	_	_
69	to	_	PART	_	_	_	_	_	_
70	upregulate	_	VERB	_	VerbForm=Inf	_	_	_	_
71	IL	_	PROPN	_	Number=Sing	_	_	_	_
72	-	_	PUNCT	_	_	_	_	_	_
73	1	_	NUM	_	NumType=Card	_	_	_	_
74	receptor	_	NOUN	_	Number=Sing	_	_	_	_
75	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
76	(	_	PUNCT	_	_	_	_	_	_
77	IL1	_	PROPN	_	Number=Sing	_	_	_	_
78	-	_	PUNCT	_	_	_	_	_	_
79	RA	_	PROPN	_	Number=Sing	_	_	_	_
80	)	_	PUNCT	_	_	_	_	_	_
81	gene	_	NOUN	_	Number=Sing	_	_	_	_
82	expression	_	NOUN	_	Number=Sing	_	_	_	_
83	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
20	evoked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	other	_	ADJ	_	Degree=Pos	_	_	_	_
23	T-helper	_	NOUN	_	Number=Sing	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
26	:	_	PUNCT	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	3	_	NUM	_	NumType=Card	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	GM-CSF	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	down	_	ADV	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
8	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	proinflammatory	_	ADJ	_	Number=Sing	_	_	_	_
12	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	beta	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	8	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	TNF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
28	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	3	_	NUM	_	NumType=Card	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	GM-CSF	_	PROPN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	suppressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	6	_	NUM	_	NumType=Card	_	_	_	_
15	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Temporal	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	down	_	ADV	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	effect	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	3	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	GM	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	CSF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
36	provided	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	evidence	_	NOUN	_	Number=Sing	_	_	_	_
38	that	_	SCONJ	_	_	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	4	_	NUM	_	NumType=Card	_	_	_	_
42	acts	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
43	predominantly	_	ADV	_	_	_	_	_	_
44	on	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	post-transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
47	level	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	supported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	observation	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	down	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	capacity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	de	_	PROPN	_	Number=Sing	_	_	_	_
23	novo	_	X	_	Number=Sing	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	exert	_	VERB	_	VerbForm=Inf	_	_	_	_
7	significant	_	ADJ	_	Degree=Pos	_	_	_	_
8	influence	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	RA	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	various	_	ADJ	_	Degree=Pos	_	_	_	_
22	CSFs	_	NOUN	_	Number=Plur	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	GM	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	CSF	_	PROPN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	0030011272	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
2	kappa	_	VERB	_	Number=Sing	_	_	_	_
3	B	_	PROPN	_	Number=Sing	_	_	_	_
4	/	_	PUNCT	_	_	_	_	_	_
5	MAD	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	3	_	NUM	_	NumType=Card	_	_	_	_
8	masks	_	VERB	_	Number=Plur	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	localization	_	NOUN	_	Number=Sing	_	_	_	_
12	signal	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	p65	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
23	domain	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	PROPN	_	Number=Sing	_	_	_	_
29	B	_	PROPN	_	Number=Sing	_	_	_	_
30	p65	_	NUM	_	Number=Sing	_	_	_	_
31	DNA	_	PROPN	_	Number=Sing	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	active	_	ADJ	_	Degree=Pos	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	form	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	complex	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	DNA	_	PROPN	_	Number=Sing	_	_	_	_
19	binding	_	VERB	_	Number=Sing	_	_	_	_
20	subunits	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	PROPN	_	Number=Sing	_	_	_	_
26	p65	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	PROPN	_	Number=Sing	_	_	_	_
31	B	_	PROPN	_	Number=Sing	_	_	_	_
32	p50	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	both	_	DET	_	_	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	which	_	PRON	_	PronType=Rel	_	_	_	_
37	share	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	extensive	_	ADJ	_	Degree=Pos	_	_	_	_
39	N	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	terminal	_	NOUN	_	Number=Sing	_	_	_	_
42	sequence	_	NOUN	_	Number=Sing	_	_	_	_
43	homology	_	NOUN	_	Number=Sing	_	_	_	_
44	with	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	v-rel	_	NOUN	_	Degree=Pos	_	_	_	_
47	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
48	product	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	PROPN	_	Number=Sing	_	_	_	_
6	p65	_	PROPN	_	Number=Sing	_	_	_	_
7	subunit	_	NOUN	_	Number=Sing	_	_	_	_
8	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	complex	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	serves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
24	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
33	kappa	_	VERB	_	Number=Sing	_	_	_	_
34	B	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	p50	_	NOUN	_	Number=Sing	_	_	_	_
9	alone	_	ADV	_	_	_	_	_	_
10	fails	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	kappa	_	PROPN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	prior	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	vitro	_	NOUN	_	Number=Sing	_	_	_	_
25	studies	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	directly	_	ADV	_	_	_	_	_	_
30	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
33	kappa	_	PROPN	_	Number=Sing	_	_	_	_
34	B	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	basis	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	critical	_	ADJ	_	Degree=Pos	_	_	_	_
9	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	interaction	_	NOUN	_	Number=Sing	_	_	_	_
11	between	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	PROPN	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	MAD	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	3	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	series	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	p65	_	NUM	_	Number=Sing	_	_	_	_
34	mutants	_	NOUN	_	Number=Plur	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	that	_	SCONJ	_	_	_	_	_	_
38	functionally	_	ADV	_	_	_	_	_	_
39	segregated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	DNA	_	PROPN	_	Number=Sing	_	_	_	_
41	binding	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
44	kappa	_	VERB	_	Number=Sing	_	_	_	_
45	B	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	mediated	_	VERB	_	Degree=Pos	_	_	_	_
48	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
52	kappa	_	VERB	_	Number=Sing	_	_	_	_
53	B	_	ADV	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
56	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
57	exclusion	_	NOUN	_	Number=Sing	_	_	_	_
58	of	_	ADP	_	_	_	_	_	_
59	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
60	transcription	_	NOUN	_	Number=Sing	_	_	_	_
61	factor	_	NOUN	_	Number=Sing	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	Results	_	NOUN	_	Number=Plur	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vivo	_	ADJ	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	studies	_	NOUN	_	Number=Plur	_	_	_	_
7	performed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	p65	_	NUM	_	Number=Sing	_	_	_	_
15	mutants	_	NOUN	_	Number=Plur	_	_	_	_
16	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	following	_	VERB	_	VerbForm=Ger	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_

1	1	_	X	_	_	_	_	_	_
2	)	_	PUNCT	_	_	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	kappa	_	VERB	_	Number=Sing	_	_	_	_
5	B	_	PROPN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	MAD	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	completely	_	ADV	_	_	_	_	_	_
11	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	p65-dependent	_	ADJ	_	Number=Sing	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
24	virus	_	NOUN	_	Number=Sing	_	_	_	_
25	type	_	NOUN	_	Number=Sing	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	2	_	X	_	_	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	binding	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
41	kappa	_	VERB	_	Number=Sing	_	_	_	_
42	B	_	PROPN	_	Number=Sing	_	_	_	_
43	/	_	PUNCT	_	_	_	_	_	_
44	MAD	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	3	_	NUM	_	NumType=Card	_	_	_	_
47	to	_	ADP	_	_	_	_	_	_
48	NF	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	kappa	_	PROPN	_	Number=Sing	_	_	_	_
51	B	_	PROPN	_	Number=Sing	_	_	_	_
52	p65	_	NOUN	_	Number=Sing	_	_	_	_
53	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
54	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
55	to	_	PART	_	_	_	_	_	_
56	retarget	_	VERB	_	VerbForm=Inf	_	_	_	_
57	NF	_	PROPN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	kappa	_	PROPN	_	Number=Sing	_	_	_	_
60	B	_	PROPN	_	Number=Sing	_	_	_	_
61	p65	_	NOUN	_	Number=Sing	_	_	_	_
62	from	_	ADP	_	_	_	_	_	_
63	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
64	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
65	to	_	ADP	_	_	_	_	_	_
66	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
67	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
68	,	_	PUNCT	_	_	_	_	_	_
69	3	_	X	_	NumType=Card	_	_	_	_
70	)	_	PUNCT	_	_	_	_	_	_
71	selective	_	ADJ	_	Degree=Pos	_	_	_	_
72	deletion	_	NOUN	_	Number=Sing	_	_	_	_
73	of	_	ADP	_	_	_	_	_	_
74	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
75	functional	_	ADJ	_	Degree=Pos	_	_	_	_
76	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
77	localization	_	NOUN	_	Number=Sing	_	_	_	_
78	signal	_	NOUN	_	Number=Sing	_	_	_	_
79	present	_	NOUN	_	Number=Sing	_	_	_	_
80	in	_	ADP	_	_	_	_	_	_
81	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
82	Rel	_	PROPN	_	Number=Sing	_	_	_	_
83	homology	_	NOUN	_	Number=Sing	_	_	_	_
84	domain	_	NOUN	_	Number=Sing	_	_	_	_
85	of	_	ADP	_	_	_	_	_	_
86	NF	_	PROPN	_	Number=Sing	_	_	_	_
87	-	_	PUNCT	_	_	_	_	_	_
88	kappa	_	PROPN	_	Number=Sing	_	_	_	_
89	B	_	PROPN	_	Number=Sing	_	_	_	_
90	p65	_	PROPN	_	Number=Sing	_	_	_	_
91	disrupts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
92	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
93	ability	_	NOUN	_	Number=Sing	_	_	_	_
94	to	_	PART	_	_	_	_	_	_
95	engage	_	VERB	_	VerbForm=Inf	_	_	_	_
96	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
97	kappa	_	VERB	_	Number=Sing	_	_	_	_
98	B	_	PROPN	_	Number=Sing	_	_	_	_
99	/	_	PUNCT	_	_	_	_	_	_
100	MAD	_	NOUN	_	Number=Sing	_	_	_	_
101	-	_	PUNCT	_	_	_	_	_	_
102	3	_	NUM	_	NumType=Card	_	_	_	_
103	,	_	PUNCT	_	_	_	_	_	_
104	and	_	CCONJ	_	_	_	_	_	_
105	4	_	X	_	_	_	_	_	_
106	)	_	PUNCT	_	_	_	_	_	_
107	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
108	unique	_	ADJ	_	Degree=Pos	_	_	_	_
109	C-	_	PUNCT	_	Number=Sing	_	_	_	_
110	terminus	_	NOUN	_	Number=Sing	_	_	_	_
111	of	_	ADP	_	_	_	_	_	_
112	NF	_	PROPN	_	Number=Sing	_	_	_	_
113	-	_	PUNCT	_	_	_	_	_	_
114	kappa	_	NOUN	_	Number=Sing	_	_	_	_
115	B	_	PROPN	_	Number=Sing	_	_	_	_
116	p65	_	NOUN	_	Number=Sing	_	_	_	_
117	attenuates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
118	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
119	own	_	ADJ	_	Degree=Pos	_	_	_	_
120	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
121	localization	_	NOUN	_	Number=Sing	_	_	_	_
122	and	_	CCONJ	_	_	_	_	_	_
123	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
124	sequences	_	NOUN	_	Number=Plur	_	_	_	_
125	that	_	PRON	_	PronType=Rel	_	_	_	_
126	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
127	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
128	for	_	ADP	_	_	_	_	_	_
129	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
130	kappa	_	VERB	_	Number=Sing	_	_	_	_
131	B	_	PROPN	_	Number=Sing	_	_	_	_
132	-	_	PUNCT	_	_	_	_	_	_
133	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
134	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
135	of	_	ADP	_	_	_	_	_	_
136	NF	_	PROPN	_	Number=Sing	_	_	_	_
137	-	_	PUNCT	_	_	_	_	_	_
138	kappa	_	NOUN	_	Number=Sing	_	_	_	_
139	B	_	PROPN	_	Number=Sing	_	_	_	_
140	p65	_	NOUN	_	Number=Sing	_	_	_	_
141	DNA	_	NOUN	_	Number=Sing	_	_	_	_
142	binding	_	NOUN	_	Number=Sing	_	_	_	_
143	activity	_	NOUN	_	Number=Sing	_	_	_	_
144	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	findings	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	localization	_	NOUN	_	Number=Sing	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
13	domain	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	PROPN	_	Number=Sing	_	_	_	_
18	B	_	PROPN	_	Number=Sing	_	_	_	_
19	p65	_	NOUN	_	Number=Sing	_	_	_	_
20	constitute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	bipartite	_	ADJ	_	Degree=Pos	_	_	_	_
23	system	_	NOUN	_	Number=Sing	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	critically	_	ADV	_	_	_	_	_	_
27	involved	_	ADJ	_	Degree=Pos	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	inhibitory	_	ADJ	_	Number=Sing	_	_	_	_
31	function	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
34	kappa	_	VERB	_	Number=Sing	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	MAD	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	3	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Unexpectedly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	vivo	_	NOUN	_	Number=Sing	_	_	_	_
6	studies	_	NOUN	_	Number=Plur	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	kappa	_	VERB	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	MAD	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	3	_	NUM	_	NumType=Card	_	_	_	_
17	binds	_	NOUN	_	Number=Plur	_	_	_	_
18	directly	_	ADV	_	_	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	PROPN	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	p50	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	interaction	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	functional	_	ADJ	_	Degree=Pos	_	_	_	_
5	as	_	SCONJ	_	_	_	_	_	_
6	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
7	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	retargeting	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	PROPN	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	p50	_	NOUN	_	Number=Sing	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	loss	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	DNA	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	presumably	_	ADV	_	_	_	_	_	_
13	reflecting	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	unique	_	ADJ	_	Degree=Pos	_	_	_	_
16	C	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	terminal	_	NOUN	_	Number=Sing	_	_	_	_
19	domain	_	NOUN	_	Number=Sing	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	present	_	ADJ	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	PROPN	_	Number=Sing	_	_	_	_
30	B	_	PROPN	_	Number=Sing	_	_	_	_
31	p65	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011273	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Evaluation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	ligand	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	thermal	_	ADJ	_	Degree=Pos	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	vitro	_	NOUN	_	Number=Sing	_	_	_	_
17	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	DNA	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
10	assay	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	capacity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	hGR	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	rabbit	_	NOUN	_	Number=Sing	_	_	_	_
26	reticulocyte	_	NOUN	_	Number=Sing	_	_	_	_
27	lysates	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
31	DNA	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	hGR	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	indistinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	native	_	ADJ	_	Degree=Pos	_	_	_	_
9	hGR	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	as	_	SCONJ	_	_	_	_	_	_
12	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	migration	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	sodium	_	NOUN	_	Number=Sing	_	_	_	_
17	dodecyl	_	NOUN	_	Degree=Pos	_	_	_	_
18	sulfate	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	polyacrylamide	_	NOUN	_	Number=Sing	_	_	_	_
21	gels	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	sedimentation	_	NOUN	_	Number=Sing	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	sucrose	_	NOUN	_	Number=Sing	_	_	_	_
26	density	_	NOUN	_	Number=Sing	_	_	_	_
27	gradients	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	reactivity	_	NOUN	_	Number=Sing	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	antipeptide	_	ADJ	_	Degree=Pos	_	_	_	_
33	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
34	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	against	_	ADP	_	_	_	_	_	_
36	hGR	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	free	_	ADJ	_	Degree=Pos	_	_	_	_
7	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	hGR	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	capable	_	ADJ	_	Degree=Pos	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
16	response	_	NOUN	_	Number=Sing	_	_	_	_
17	element	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	GRE	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	DNA	_	NOUN	_	Number=Sing	_	_	_	_
24	fragments	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	assay	_	NOUN	_	Number=Sing	_	_	_	_
4	system	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	evaluated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	contributions	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	ligand	_	NOUN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	heat	_	NOUN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	DNA	_	PROPN	_	Number=Sing	_	_	_	_
19	binding	_	VERB	_	Number=Sing	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
22	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
23	receptors	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	hGR	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	capable	_	ADJ	_	Degree=Pos	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	selective	_	ADJ	_	Degree=Pos	_	_	_	_
9	DNA	_	PROPN	_	Number=Sing	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	even	_	ADV	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	absence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	antiglucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
7	RU486	_	PROPN	_	Number=Sing	_	_	_	_
8	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	no	_	DET	_	_	_	_	_	_
10	additional	_	ADJ	_	Degree=Pos	_	_	_	_
11	effect	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	DNA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	capacity	_	NOUN	_	Number=Sing	_	_	_	_
18	when	_	ADV	_	PronType=Int	_	_	_	_
19	receptor	_	ADJ	_	Number=Sing	_	_	_	_
20	preparations	_	NOUN	_	Number=Plur	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	maintained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	at	_	ADP	_	_	_	_	_	_
24	0	_	NUM	_	NumType=Card	_	_	_	_
25	C	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	no	_	DET	_	_	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	addition	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	either	_	CCONJ	_	_	_	_	_	_
7	ligand	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	combination	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	heat	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	step	_	NOUN	_	Number=Sing	_	_	_	_
17	promoted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	DNA	_	PROPN	_	Number=Sing	_	_	_	_
19	binding	_	VERB	_	Number=Sing	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	approximately	_	ADV	_	_	_	_	_	_
22	3	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	fold	_	NOUN	_	Number=Sing	_	_	_	_
25	over	_	ADP	_	_	_	_	_	_
26	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	heat	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	unliganded	_	ADJ	_	Degree=Pos	_	_	_	_
32	receptors	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Agonist	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	slightly	_	ADV	_	_	_	_	_	_
7	more	_	ADV	_	_	_	_	_	_
8	effective	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	SCONJ	_	_	_	_	_	_
10	supporting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	than	_	ADP	_	_	_	_	_	_
15	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	RU486	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	vitro	_	NOUN	_	Number=Sing	_	_	_	_
6	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	GR	_	PROPN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	addition	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	sodium	_	NOUN	_	Number=Sing	_	_	_	_
15	molybdate	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	preparations	_	NOUN	_	Number=Plur	_	_	_	_
20	before	_	ADP	_	_	_	_	_	_
21	steroid	_	NOUN	_	Number=Sing	_	_	_	_
22	addition	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	thermal	_	ADJ	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Addition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	KCl	_	PROPN	_	Number=Sing	_	_	_	_
4	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	less	_	ADJ	_	Degree=Cmp	_	_	_	_
7	DNA	_	PROPN	_	Number=Sing	_	_	_	_
8	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
9	either	_	CCONJ	_	_	_	_	_	_
10	due	_	ADP	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	blockage	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	DNA	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	complex	_	ADJ	_	Degree=Pos	_	_	_	_
18	formation	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	disruption	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	complexes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	specificity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	DNA	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	VERB	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	free	_	ADJ	_	Degree=Pos	_	_	_	_
10	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	hGR	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	further	_	ADV	_	_	_	_	_	_
15	by	_	SCONJ	_	_	_	_	_	_
16	examining	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	abilities	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	various	_	ADJ	_	Degree=Pos	_	_	_	_
21	DNAs	_	NOUN	_	Number=Plur	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	compete	_	VERB	_	VerbForm=Inf	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	binding	_	VERB	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	naturally	_	ADV	_	_	_	_	_	_
29	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
30	GRE	_	NOUN	_	Number=Sing	_	_	_	_
31	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	mouse	_	NOUN	_	Number=Sing	_	_	_	_
35	mammary	_	ADJ	_	Number=Sing	_	_	_	_
36	tumor	_	NOUN	_	Number=Sing	_	_	_	_
37	virus	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	long	_	ADJ	_	Degree=Pos	_	_	_	_
40	terminal	_	NOUN	_	Number=Sing	_	_	_	_
41	repeat	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
2	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	consensus	_	NOUN	_	Number=Sing	_	_	_	_
5	GRE	_	NOUN	_	Number=Sing	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	most	_	ADV	_	_	_	_	_	_
9	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
10	competitors	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	fragments	_	NOUN	_	Number=Plur	_	_	_	_
14	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	sequences	_	NOUN	_	Number=Plur	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	repressible	_	ADJ	_	Degree=Pos	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	somewhat	_	ADV	_	_	_	_	_	_
24	competitive	_	ADJ	_	Degree=Pos	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	whereas	_	SCONJ	_	_	_	_	_	_
27	single	_	ADJ	_	Degree=Pos	_	_	_	_
28	stranded	_	VERB	_	Degree=Pos	_	_	_	_
29	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
30	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	unable	_	ADJ	_	Degree=Pos	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	compete	_	VERB	_	VerbForm=Inf	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	mouse	_	NOUN	_	Number=Sing	_	_	_	_
36	mammary	_	ADJ	_	Number=Sing	_	_	_	_
37	tumor	_	NOUN	_	Number=Sing	_	_	_	_
38	virus	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	long	_	ADJ	_	Degree=Pos	_	_	_	_
41	terminal	_	NOUN	_	Number=Sing	_	_	_	_
42	repeat	_	VERB	_	Number=Sing	_	_	_	_
43	DNA	_	NOUN	_	Number=Sing	_	_	_	_
44	binding	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	except	_	ADP	_	_	_	_	_	_
47	when	_	ADV	_	PronType=Int	_	_	_	_
48	competitor	_	NOUN	_	Number=Sing	_	_	_	_
49	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
50	present	_	ADJ	_	Degree=Pos	_	_	_	_
51	at	_	ADP	_	_	_	_	_	_
52	extremely	_	ADV	_	_	_	_	_	_
53	high	_	ADJ	_	Degree=Pos	_	_	_	_
54	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	hGR	_	NOUN	_	Number=Sing	_	_	_	_
7	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	rabbit	_	NOUN	_	Number=Sing	_	_	_	_
10	reticulocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	lysates	_	NOUN	_	Number=Plur	_	_	_	_
12	displays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	many	_	ADJ	_	Degree=Pos	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	same	_	ADJ	_	Degree=Pos	_	_	_	_
17	properties	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	including	_	VERB	_	VerbForm=Ger	_	_	_	_
20	GRE	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	DNA	_	PROPN	_	Number=Sing	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	present	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
33	extracts	_	NOUN	_	Number=Plur	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	tissues	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Similarities	_	NOUN	_	Number=Plur	_	_	_	_
2	between	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	RU486	_	PROPN	_	Number=Sing	_	_	_	_
9	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	antiglucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
13	properties	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	RU486	_	NOUN	_	Number=Sing	_	_	_	_
16	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
19	at	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	level	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	DNA	_	PROPN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011281	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Thrombin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	p65	_	NUM	_	Number=Sing	_	_	_	_
5	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	mediates	_	NOUN	_	Number=Plur	_	_	_	_
18	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
19	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
25	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Int	_	_	_	_
7	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	mediator	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	released	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	during	_	ADP	_	_	_	_	_	_
14	intravascular	_	ADJ	_	Degree=Pos	_	_	_	_
15	coagulation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	tissue	_	NOUN	_	Number=Sing	_	_	_	_
18	injury	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	CD54	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HUVEC	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
6	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	dose	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	time	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	increases	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	surface	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
31	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
32	adhesivity	_	NOUN	_	Number=Sing	_	_	_	_
33	toward	_	ADP	_	_	_	_	_	_
34	polymorphonuclear	_	ADJ	_	Degree=Pos	_	_	_	_
35	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
12	reporter	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1LUC	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	constructs	_	NOUN	_	Number=Plur	_	_	_	_
20	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	deletion	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	site	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	-	_	SYM	_	_	_	_	_	_
32	533	_	NUM	_	NumType=Card	_	_	_	_
33	bases	_	NOUN	_	Number=Plur	_	_	_	_
34	from	_	ADP	_	_	_	_	_	_
35	translation	_	NOUN	_	Number=Sing	_	_	_	_
36	start	_	NOUN	_	Number=Sing	_	_	_	_
37	site	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	no	_	DET	_	_	_	_	_	_
41	effect	_	NOUN	_	Number=Sing	_	_	_	_
42	on	_	ADP	_	_	_	_	_	_
43	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
44	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	whereas	_	SCONJ	_	_	_	_	_	_
47	mutation	_	NOUN	_	Number=Sing	_	_	_	_
48	/	_	PUNCT	_	_	_	_	_	_
49	deletion	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
52	NF	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	kappa	_	NOUN	_	Number=Sing	_	_	_	_
55	B	_	NOUN	_	Number=Sing	_	_	_	_
56	site	_	NOUN	_	Number=Sing	_	_	_	_
57	(	_	PUNCT	_	_	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	223	_	NUM	_	NumType=Card	_	_	_	_
60	bases	_	NOUN	_	Number=Plur	_	_	_	_
61	from	_	ADP	_	_	_	_	_	_
62	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
63	translation	_	NOUN	_	Number=Sing	_	_	_	_
64	start	_	NOUN	_	Number=Sing	_	_	_	_
65	site	_	NOUN	_	Number=Sing	_	_	_	_
66	)	_	PUNCT	_	_	_	_	_	_
67	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
68	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
69	activation	_	NOUN	_	Number=Sing	_	_	_	_
70	of	_	ADP	_	_	_	_	_	_
71	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
72	-	_	PUNCT	_	_	_	_	_	_
73	1	_	NUM	_	NumType=Card	_	_	_	_
74	promoter	_	NOUN	_	Number=Sing	_	_	_	_
75	,	_	PUNCT	_	_	_	_	_	_
76	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
77	that	_	SCONJ	_	_	_	_	_	_
78	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
79	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
80	NF	_	PROPN	_	Number=Sing	_	_	_	_
81	-	_	PUNCT	_	_	_	_	_	_
82	kappa	_	NOUN	_	Number=Sing	_	_	_	_
83	B	_	NOUN	_	Number=Sing	_	_	_	_
84	site	_	NOUN	_	Number=Sing	_	_	_	_
85	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
86	critical	_	ADJ	_	Degree=Pos	_	_	_	_
87	for	_	ADP	_	_	_	_	_	_
88	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
89	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
90	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	approximately	_	ADV	_	_	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	fold	_	NOUN	_	VerbForm=Inf	_	_	_	_
14	when	_	ADV	_	PronType=Int	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	transfected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	plasmid	_	ADJ	_	Degree=Pos	_	_	_	_
20	pNF	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	BLUC	_	PROPN	_	Number=Sing	_	_	_	_
24	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
25	five	_	NUM	_	NumType=Card	_	_	_	_
26	copies	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	consensus	_	NOUN	_	Number=Sing	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	site	_	NOUN	_	Number=Sing	_	_	_	_
34	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
38	adenovirus	_	NOUN	_	Number=Sing	_	_	_	_
39	E1B	_	NOUN	_	Number=Sing	_	_	_	_
40	promoter	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
43	gene	_	NOUN	_	Number=Sing	_	_	_	_
44	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
45	exposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
46	to	_	ADP	_	_	_	_	_	_
47	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
50	that	_	SCONJ	_	_	_	_	_	_
51	activation	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	NF	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	kappa	_	NOUN	_	Number=Sing	_	_	_	_
56	B	_	NOUN	_	Number=Sing	_	_	_	_
57	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
58	essential	_	ADJ	_	Degree=Pos	_	_	_	_
59	for	_	ADP	_	_	_	_	_	_
60	thrombin	_	ADJ	_	Degree=Pos	_	_	_	_
61	response	_	NOUN	_	Number=Sing	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	supershift	_	NOUN	_	Number=Sing	_	_	_	_
3	assays	_	NOUN	_	Number=Plur	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	Bp65	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	Rel	_	NOUN	_	Number=Sing	_	_	_	_
16	A	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Thrombin	_	PROPN	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	peptide	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	14	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	amino	_	ADJ	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	acid	_	ADJ	_	Number=Sing	_	_	_	_
12	peptide	_	NOUN	_	Number=Sing	_	_	_	_
13	representing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	new	_	ADJ	_	Degree=Pos	_	_	_	_
16	NH2	_	PROPN	_	Number=Sing	_	_	_	_
17	terminus	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	proteolytically	_	ADV	_	_	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	mimicked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
27	's	_	PART	_	_	_	_	_	_
28	action	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	SCONJ	_	_	_	_	_	_
30	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
31	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
6	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
8	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	polymorphonuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	Bp65	_	NOUN	_	Number=Sing	_	_	_	_
21	binding	_	VERB	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	site	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	after	_	ADP	_	_	_	_	_	_
36	proteolytically	_	ADV	_	_	_	_	_	_
37	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	receptor	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	activation	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011282	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	c	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	jun	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	kappa	_	PROPN	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	nucleated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
17	fetal	_	ADJ	_	Degree=Pos	_	_	_	_
18	blood	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	up	_	ADP	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	regulation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	c	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	fos	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	anti-CD3	_	ADJ	_	Degree=Pos	_	_	_	_
32	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Fetal	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	relatively	_	ADV	_	_	_	_	_	_
7	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	when	_	ADV	_	PronType=Int	_	_	_	_
14	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	either	_	CCONJ	_	_	_	_	_	_
16	via	_	ADP	_	_	_	_	_	_
17	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
19	antigen	_	NOUN	_	Number=Sing	_	_	_	_
20	receptors	_	NOUN	_	Number=Plur	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	lectins	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	s	_	X	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
11	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	clearly	_	ADV	_	_	_	_	_	_
15	elucidated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	hypothesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	such	_	ADJ	_	Degree=Pos	_	_	_	_
6	defects	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	fetal	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
11	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	due	_	ADP	_	_	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	lack	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	elements	_	NOUN	_	Number=Plur	_	_	_	_
25	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	T	_	NUM	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	reverse	_	NOUN	_	Number=Sing	_	_	_	_
4	transcriptase	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
7	chain	_	NOUN	_	Number=Sing	_	_	_	_
8	reaction	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	fetal	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	term	_	NOUN	_	Number=Sing	_	_	_	_
15	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
16	cord	_	NOUN	_	Number=Sing	_	_	_	_
17	bloods	_	NOUN	_	Number=Plur	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	three	_	NUM	_	NumType=Card	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factors	_	NOUN	_	Number=Plur	_	_	_	_
25	implicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	:	_	PUNCT	_	_	_	_	_	_
30	c	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	jun	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	kappa	_	PROPN	_	Number=Sing	_	_	_	_
39	B	_	PROPN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	p50	_	NUM	_	Number=Sing	_	_	_	_
42	subunit	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	all	_	DET	_	_	_	_	_	_
7	three	_	NUM	_	NumType=Card	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
10	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	fetal	_	ADJ	_	Degree=Pos	_	_	_	_
16	blood	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	27th	_	ADJ	_	Number=Sing	_	_	_	_
21	week	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	gestation	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	term	_	NOUN	_	Number=Sing	_	_	_	_
27	cord	_	NOUN	_	Number=Sing	_	_	_	_
28	bloods	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	term	_	NOUN	_	Number=Sing	_	_	_	_
4	infant	_	NOUN	_	Number=Sing	_	_	_	_
5	cord	_	NOUN	_	Number=Sing	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	anti-CD3	_	ADJ	_	Degree=Pos	_	_	_	_
11	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
12	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
13	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	up	_	ADP	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	both	_	DET	_	_	_	_	_	_
20	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	c	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	fos	_	ADP	_	Number=Sing	_	_	_	_
25	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
26	within	_	ADP	_	_	_	_	_	_
27	15	_	NUM	_	NumType=Card	_	_	_	_
28	min	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	secretion	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	anti-CD3	_	ADJ	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	cord	_	NOUN	_	Number=Sing	_	_	_	_
13	blood	_	NOUN	_	Number=Sing	_	_	_	_
14	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	still	_	ADV	_	_	_	_	_	_
18	blunted	_	VERB	_	Degree=Pos	_	_	_	_
19	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	control	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	adults	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	fetal	_	NOUN	_	Number=Sing	_	_	_	_
5	nucleated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	constitutively	_	ADV	_	_	_	_	_	_
9	express	_	VERB	_	Degree=Pos	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	cytokine	_	VERB	_	Degree=Pos	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	able	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
20	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
21	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
27	factors	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	response	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	anti-CD3	_	ADJ	_	Degree=Pos	_	_	_	_
32	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	qualitative	_	ADJ	_	Degree=Pos	_	_	_	_
4	differences	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	capacity	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	could	_	AUX	_	VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	fetal	_	ADJ	_	Degree=Pos	_	_	_	_
18	blood	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Quantitative	_	ADJ	_	Degree=Pos	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	comparing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	currently	_	ADV	_	_	_	_	_	_
17	under	_	ADP	_	_	_	_	_	_
18	investigation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011284	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Triggering	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	complement	_	NOUN	_	Number=Sing	_	_	_	_
4	receptors	_	NOUN	_	Number=Plur	_	_	_	_
5	CR1	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	CD35	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	CR3	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	CD18	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	translocation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	p50	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	p65	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	enhances	_	VERB	_	Number=Plur	_	_	_	_
34	viral	_	ADJ	_	Degree=Pos	_	_	_	_
35	replication	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	HIV	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Monocyte	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
4	may	_	AUX	_	VerbForm=Fin	_	_	_	_
5	harbor	_	VERB	_	VerbForm=Inf	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	nonproductive	_	ADJ	_	Degree=Pos	_	_	_	_
10	fashion	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	prolonged	_	VERB	_	Degree=Pos	_	_	_	_
13	periods	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	time	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Viral	_	ADJ	_	Degree=Pos	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	may	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	reactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	LPS	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
16	such	_	ADJ	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	TNF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	vitro	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	LPS	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	TNF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	ability	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	translocation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	DNA	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	binding	_	VERB	_	Number=Sing	_	_	_	_
23	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	p50	_	NOUN	_	Number=Sing	_	_	_	_
30	/	_	SYM	_	_	_	_	_	_
31	p65	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	which	_	PRON	_	PronType=Rel	_	_	_	_
35	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	specific	_	ADJ	_	Degree=Pos	_	_	_	_
39	sequence	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	HIV	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	long	_	ADJ	_	Degree=Pos	_	_	_	_
45	terminal	_	NOUN	_	Number=Sing	_	_	_	_
46	repeat	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	triggering	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	complement	_	NOUN	_	Number=Sing	_	_	_	_
9	receptors	_	NOUN	_	Number=Plur	_	_	_	_
10	CR1	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	CD35	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	CR3	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	CD18	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	viral	_	ADJ	_	Degree=Pos	_	_	_	_
23	replication	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	normal	_	ADJ	_	Degree=Pos	_	_	_	_
6	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
7	blood	_	NOUN	_	Number=Sing	_	_	_	_
8	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	infected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	vitro	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	presence	_	NOUN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	absence	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	F	_	PROPN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	ab	_	NOUN	_	Number=Sing	_	_	_	_
28	'	_	PUNCT	_	_	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	fragments	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
34	anti-CR1	_	NOUN	_	Number=Sing	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	anti-CR3	_	NOUN	_	Degree=Pos	_	_	_	_
37	Abs	_	NOUN	_	Number=Plur	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	C3	_	NOUN	_	Number=Sing	_	_	_	_
41	fragments	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CR1	_	NOUN	_	Number=Sing	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	CR3	_	PROPN	_	Number=Sing	_	_	_	_
6	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	fourfold	_	VERB	_	VerbForm=Inf	_	_	_	_
12	increase	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	amount	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	released	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	p24	_	NOUN	_	Number=Sing	_	_	_	_

1	Ag	_	NOUN	_	Number=Sing	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	cultures	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	equivalent	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	control	_	NOUN	_	Number=Sing	_	_	_	_
13	cultures	_	NOUN	_	Number=Plur	_	_	_	_
14	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	LPS	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CR1	_	PROPN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	CR3	_	PROPN	_	Number=Sing	_	_	_	_
10	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	translocation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	p50/p65	_	NUM	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Translocation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_
6	B	_	PROPN	_	Number=Sing	_	_	_	_
7	p50/p65	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	following	_	VERB	_	VerbForm=Ger	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	CR1	_	NOUN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	CR3	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	uninfected	_	ADJ	_	Degree=Pos	_	_	_	_
19	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
20	blood	_	NOUN	_	Number=Sing	_	_	_	_
21	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	HIV	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	seronegative	_	ADJ	_	Degree=Pos	_	_	_	_
26	donors	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	amount	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	translocated	_	VERB	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	similar	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	when	_	ADV	_	PronType=Int	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	rhTNF	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	PROPN	_	Number=Sing	_	_	_	_
4	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	translocation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	p50/p65	_	NUM	_	Number=Sing	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	triggering	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	complement	_	NOUN	_	Number=Sing	_	_	_	_
20	receptors	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	observations	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	HIV	_	ADJ	_	Degree=Pos	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	infected	_	VERB	_	Degree=Pos	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	through	_	ADP	_	_	_	_	_	_
18	interaction	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	complement	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	opsonized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	particles	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	that	_	DET	_	_	_	_	_	_
29	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	viral	_	ADJ	_	Degree=Pos	_	_	_	_
31	replication	_	NOUN	_	Number=Sing	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	C3	_	PROPN	_	Number=Sing	_	_	_	_
36	receptor	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
40	translocation	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	NF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kappa	_	NOUN	_	Number=Sing	_	_	_	_
46	B	_	NOUN	_	Number=Sing	_	_	_	_
47	complex	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011288	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	carboxyl	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
5	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
6	domain	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	CD36	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	oxidized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	low	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	density	_	NOUN	_	Number=Sing	_	_	_	_
16	lipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
17	modulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	tumor	_	NOUN	_	Number=Sing	_	_	_	_
25	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	oxidized	_	VERB	_	Degree=Pos	_	_	_	_
5	low	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	density	_	NOUN	_	Number=Sing	_	_	_	_
8	lipoprotein	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	Ox	_	CCONJ	_	Number=Sing	_	_	_	_
11	LDL	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
17	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	pleiotropic	_	ADJ	_	Degree=Pos	_	_	_	_
19	effects	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	including	_	VERB	_	VerbForm=Ger	_	_	_	_
22	changes	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	early	_	ADJ	_	Degree=Pos	_	_	_	_
34	event	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	atherogenesis	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	integral	_	ADJ	_	Degree=Pos	_	_	_	_
3	membrane	_	NOUN	_	Number=Sing	_	_	_	_
4	glycoprotein	_	PROPN	_	Number=Sing	_	_	_	_
5	CD36	_	PROPN	_	Number=Sing	_	_	_	_
6	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	play	_	VERB	_	VerbForm=Inf	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	uptake	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Ox	_	NOUN	_	Number=Sing	_	_	_	_
18	LDL	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	although	_	SCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
27	events	_	NOUN	_	Number=Plur	_	_	_	_
28	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	CD36	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	Ox	_	NOUN	_	Number=Sing	_	_	_	_
33	LDL	_	PROPN	_	Number=Sing	_	_	_	_
34	interaction	_	NOUN	_	Number=Sing	_	_	_	_
35	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	approach	_	VERB	_	VerbForm=Inf	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	issue	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	CD36	_	PROPN	_	Number=Sing	_	_	_	_
9	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	Chinese	_	ADJ	_	Degree=Pos	_	_	_	_
11	hampster	_	NOUN	_	Number=Sing	_	_	_	_
12	ovary	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	CHO	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	exposed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	Ox	_	NOUN	_	Number=Sing	_	_	_	_
22	LDL	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	determined	_	VERB	_	Degree=Pos	_	_	_	_
26	changes	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Ox	_	PROPN	_	Number=Sing	_	_	_	_
6	LDL	_	PROPN	_	Number=Sing	_	_	_	_
7	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	DNA	_	PROPN	_	Number=Sing	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	extracts	_	NOUN	_	Number=Plur	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	sequence	_	NOUN	_	Number=Sing	_	_	_	_
20	following	_	VERB	_	VerbForm=Ger	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	CD36	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	CHO	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
32	tumor	_	NOUN	_	Number=Sing	_	_	_	_
33	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
34	factor	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	TNF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	alpha	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	coincubation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	CD36	_	PROPN	_	Number=Sing	_	_	_	_
12	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	CD36	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	antibody	_	NOUN	_	Number=Sing	_	_	_	_
21	OKM5	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	determined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	DNA	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	required	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	intact	_	ADJ	_	Degree=Pos	_	_	_	_
16	carboxyl	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
19	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
20	segment	_	NOUN	_	Number=Sing	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	CD36	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	idea	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	ADV	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	CD36	_	PROPN	_	Number=Sing	_	_	_	_
9	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	transduction	_	NOUN	_	Number=Sing	_	_	_	_
12	events	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	Ox	_	NOUN	_	Number=Sing	_	_	_	_
17	LDL	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011290	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	base	_	NOUN	_	Number=Sing	_	_	_	_
3	pair	_	NOUN	_	Number=Sing	_	_	_	_
4	change	_	NOUN	_	Number=Sing	_	_	_	_
5	abolishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	T	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	kB	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	like	_	ADJ	_	Degree=Pos	_	_	_	_
17	proto	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
20	element	_	NOUN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inducible	_	ADJ	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	murine	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	Interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	Il	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	kB	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	like	_	ADJ	_	Degree=Pos	_	_	_	_
26	sequence	_	NOUN	_	Number=Sing	_	_	_	_
27	GGGATTTCACC	_	PROPN	_	Number=Sing	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	essential	_	ADJ	_	Degree=Pos	_	_	_	_
31	cis	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
34	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
35	motif	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
5	copies	_	NOUN	_	Number=Plur	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	so	_	ADV	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	TCEd	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	distal	_	ADJ	_	Degree=Pos	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	element	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
21	proto	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
24	element	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	E14	_	PROPN	_	NumType=Card	_	_	_	_
27	T	_	PROPN	_	Number=Sing	_	_	_	_
28	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	but	_	CCONJ	_	_	_	_	_	_
32	not	_	PART	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	extracts	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	induced	_	VERB	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	Il	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	secreting	_	VERB	_	Number=Sing	_	_	_	_
10	El4	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	three	_	NUM	_	NumType=Card	_	_	_	_
13	individual	_	ADJ	_	Degree=Pos	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	TCEd	_	VERB	_	Number=Sing	_	_	_	_
19	DNA	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	most	_	ADV	_	_	_	_	_	_
6	prominent	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	named	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	TCF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	T	_	PROPN	_	NumType=Card	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	proto	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	TCEd	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	TCF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	consists	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	polypeptides	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	about	_	ADV	_	_	_	_	_	_
10	50	_	NUM	_	NumType=Card	_	_	_	_
11	kD	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	105	_	NUM	_	NumType=Card	_	_	_	_
14	kD	_	NOUN	_	Number=Sing	_	_	_	_
15	;	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	former	_	ADJ	_	Degree=Pos	_	_	_	_
18	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	related	_	ADJ	_	Degree=Pos	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	50	_	NUM	_	NumType=Card	_	_	_	_
25	kD	_	NOUN	_	Number=Sing	_	_	_	_
26	polypeptide	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kB	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kB	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	able	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	TCEd	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	TCF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	binds	_	NOUN	_	Number=Plur	_	_	_	_
19	stronger	_	ADJ	_	Degree=Cmp	_	_	_	_
20	than	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kB	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	TCEd	_	PROPN	_	Number=Sing	_	_	_	_
26	DNA	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	conversion	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	TCEd	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	'	_	PUNCT	_	_	_	_	_	_
9	perfect	_	ADJ	_	Degree=Pos	_	_	_	_
10	'	_	PUNCT	_	_	_	_	_	_
11	NF	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kB	_	NOUN	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	tighter	_	ADJ	_	Degree=Cmp	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kB	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	TCEd	_	PROPN	_	Number=Sing	_	_	_	_
27	DNA	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	functional	_	ADJ	_	Degree=Pos	_	_	_	_
33	consequence	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	activity	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	'	_	PUNCT	_	_	_	_	_	_
41	converted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	'	_	PUNCT	_	_	_	_	_	_
43	TCEd	_	VERB	_	Number=Sing	_	_	_	_
44	motifs	_	NOUN	_	Number=Plur	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	substitution	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	underlined	_	VERB	_	Degree=Pos	_	_	_	_
8	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	residue	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	C	_	NOUN	_	Number=Sing	_	_	_	_
13	within	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	GGGATTTCACC	_	PROPN	_	Number=Sing	_	_	_	_
16	motif	_	NOUN	_	Number=Sing	_	_	_	_
17	abolishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	T	_	NUM	_	NumType=Card	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	functioning	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	both	_	CCONJ	_	_	_	_	_	_
31	El4	_	PROPN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	TCEd	_	PROPN	_	Number=Sing	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	involved	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	control	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	specific	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	Il	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011296	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	through	_	ADP	_	_	_	_	_	_
13	CD28	_	PROPN	_	Number=Sing	_	_	_	_
14	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
16	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	5	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	lipoxygenase	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CD28	_	PROPN	_	Number=Sing	_	_	_	_
5	surface	_	NOUN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	major	_	ADJ	_	Degree=Pos	_	_	_	_
10	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	signal	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	T	_	NUM	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	production	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	primary	_	ADJ	_	Degree=Pos	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	CD28	_	PROPN	_	Number=Sing	_	_	_	_
9	ligation	_	NOUN	_	Number=Sing	_	_	_	_
10	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
14	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	formation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
18	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
19	intermediates	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	ROIs	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	CD28	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	mediated	_	VERB	_	Degree=Pos	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	PROPN	_	Number=Sing	_	_	_	_
36	B/CD28	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
39	complex	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	2	_	NUM	_	NumType=Card	_	_	_	_
44	expression	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Delineation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CD28	_	PROPN	_	Number=Sing	_	_	_	_
5	signaling	_	NOUN	_	Number=Sing	_	_	_	_
6	cascade	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	phospholipase	_	NOUN	_	Number=Sing	_	_	_	_
22	A2	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	5	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	lipoxygenase	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	lipoxygenase	_	NOUN	_	Number=Sing	_	_	_	_
6	metabolites	_	NOUN	_	Number=Plur	_	_	_	_
7	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	ROI	_	PROPN	_	Number=Sing	_	_	_	_
9	formation	_	NOUN	_	Number=Sing	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	then	_	ADV	_	PronType=Dem	_	_	_	_
12	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	via	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	should	_	AUX	_	VerbForm=Fin	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	useful	_	ADJ	_	Degree=Pos	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
8	strategies	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	development	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	immunosuppressants	_	NOUN	_	Number=Plur	_	_	_	_
14	targeting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	CD28	_	PROPN	_	Number=Sing	_	_	_	_
17	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	pathway	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011298	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CD2	_	PROPN	_	Number=Sing	_	_	_	_
2	signalling	_	NOUN	_	Number=Sing	_	_	_	_
3	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CREB	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	primary	_	ADJ	_	Degree=Pos	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Promoter	_	NOUN	_	Number=Sing	_	_	_	_
2	sequences	_	NOUN	_	Number=Plur	_	_	_	_
3	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	cyclic	_	ADJ	_	Degree=Pos	_	_	_	_
6	AMP	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	number	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
26	response	_	NOUN	_	Number=Sing	_	_	_	_
27	element	_	NOUN	_	Number=Sing	_	_	_	_
28	binding	_	VERB	_	Number=Sing	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	CREB	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	/	_	PUNCT	_	_	_	_	_	_
34	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	factor	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	ATF	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	_	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	family	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	T-lymphotropic	_	ADJ	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	model	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	element	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	CRE	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	influence	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	lymphocyte	_	ADJ	_	Number=Sing	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	on	_	ADP	_	_	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	from	_	ADP	_	_	_	_	_	_
34	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
35	regions	_	NOUN	_	Number=Plur	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	viral	_	ADJ	_	Degree=Pos	_	_	_	_
39	promoter	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	following	_	VERB	_	VerbForm=Ger	_	_	_	_
10	CD2	_	NOUN	_	Number=Sing	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	ADV	_	_	_	_	_	_
13	CD3	_	NOUN	_	Number=Sing	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	cross	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	linking	_	VERB	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	hypothesized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	viral	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	part	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	CREB	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	CD2	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	CD3	_	PROPN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	signalling	_	VERB	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	primary	_	ADJ	_	Degree=Pos	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
16	blood	_	NOUN	_	Number=Sing	_	_	_	_
17	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	CD2	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	but	_	CCONJ	_	_	_	_	_	_
4	not	_	ADV	_	_	_	_	_	_
5	CD3	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	cross	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
12	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	competitive	_	ADJ	_	Degree=Pos	_	_	_	_
15	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	immunosorbent	_	ADJ	_	Degree=Pos	_	_	_	_
19	assay	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	ELISA	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	approximately	_	ADV	_	_	_	_	_	_
24	fourfold	_	VERB	_	NumType=Card	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	CD2	_	PROPN	_	Number=Sing	_	_	_	_
2	cross	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	linking	_	VERB	_	Number=Sing	_	_	_	_
5	concurrently	_	ADV	_	_	_	_	_	_
6	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	CREB	_	PROPN	_	Number=Sing	_	_	_	_
10	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	immunoblot	_	NOUN	_	Number=Sing	_	_	_	_
13	assay	_	VERB	_	Number=Sing	_	_	_	_
14	eightfold	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	post	_	NOUN	_	_	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	translational	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	no	_	DET	_	_	_	_	_	_
9	change	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	total	_	ADJ	_	Degree=Pos	_	_	_	_
12	level	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	CREB	_	PROPN	_	Number=Sing	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CREB	_	PROPN	_	Number=Sing	_	_	_	_
4	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	through	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	herbimycin	_	NOUN	_	Number=Sing	_	_	_	_
8	A	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	Rp-cAMP	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
13	pathway	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
17	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	antecedent	_	ADJ	_	Degree=Pos	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	both	_	DET	_	_	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
24	kinases	_	NOUN	_	Number=Plur	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	PTK	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	A	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	PKA	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	CD2	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	CD3	_	PROPN	_	Number=Sing	_	_	_	_
5	cross	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
8	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	radiolabelled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	CRE	_	NOUN	_	Number=Sing	_	_	_	_
17	oligonucleotide	_	ADJ	_	Number=Sing	_	_	_	_
18	probe	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
21	mobility	_	NOUN	_	Number=Sing	_	_	_	_
22	shift	_	NOUN	_	Number=Sing	_	_	_	_
23	assays	_	NOUN	_	Number=Plur	_	_	_	_
24	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	enhances	_	NOUN	_	Number=Plur	_	_	_	_
29	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
30	independently	_	ADV	_	_	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	CREB	_	NOUN	_	Number=Sing	_	_	_	_
35	at	_	ADP	_	_	_	_	_	_
36	serine	_	NOUN	_	Number=Sing	_	_	_	_
37	133	_	NUM	_	NumType=Card	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	modulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	CREB	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	ATF	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	family	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	CD2	_	PROPN	_	Number=Sing	_	_	_	_
20	signalling	_	NOUN	_	Number=Sing	_	_	_	_
21	pathway	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	CD2	_	PROPN	_	Number=Sing	_	_	_	_
25	receptor	_	NOUN	_	Number=Sing	_	_	_	_
26	modulation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	CRE	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	following	_	VERB	_	VerbForm=Ger	_	_	_	_
33	ligand	_	NOUN	_	Number=Sing	_	_	_	_
34	engagement	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	e.g.	_	ADV	_	_	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	contact	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011301	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	5'-	_	ADJ	_	_	_	_	_	_
13	untranslated	_	ADJ	_	Degree=Pos	_	_	_	_
14	leader	_	NOUN	_	Number=Sing	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	review	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	interaction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	host	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	cis	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	DNA	_	NOUN	_	Number=Sing	_	_	_	_
29	elements	_	NOUN	_	Number=Plur	_	_	_	_
30	within	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	viral	_	ADJ	_	Degree=Pos	_	_	_	_
33	long	_	ADJ	_	Degree=Pos	_	_	_	_
34	terminal	_	NOUN	_	Number=Sing	_	_	_	_
35	repeat	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	LTR	_	PROPN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Much	_	ADJ	_	Degree=Pos	_	_	_	_
2	attention	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	focused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	series	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	sequence	_	NOUN	_	Number=Sing	_	_	_	_
10	elements	_	NOUN	_	Number=Plur	_	_	_	_
11	upstream	_	NOUN	_	_	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	initiation	_	NOUN	_	Number=Sing	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	U3	_	PROPN	_	Number=Sing	_	_	_	_
20	region	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	LTR	_	PROPN	_	Number=Sing	_	_	_	_
24	including	_	VERB	_	VerbForm=Ger	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	binding	_	NOUN	_	Number=Sing	_	_	_	_
32	sites	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	however	_	ADV	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcribed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	5'-	_	PUNCT	_	_	_	_	_	_
11	untranslated	_	ADJ	_	Degree=Pos	_	_	_	_
12	leader	_	NOUN	_	Number=Sing	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	5'	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	UTR	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	important	_	ADJ	_	Degree=Pos	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	elements	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	elements	_	NOUN	_	Number=Plur	_	_	_	_
4	situated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	downstream	_	ADV	_	Degree=Pos	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	interact	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	mediate	_	ADJ	_	Degree=Pos	_	_	_	_
17	transmission	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	signals	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	important	_	ADJ	_	Degree=Pos	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
28	HIV	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	replication	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	5'-	_	NUM	_	Number=Sing	_	_	_	_
3	UTR	_	PROPN	_	Number=Sing	_	_	_	_
4	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	binding	_	NOUN	_	VerbForm=Ger	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	AT	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	IRF	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	binding	_	NOUN	_	Degree=Pos	_	_	_	_
5	sites	_	NOUN	_	Number=Plur	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	interfere	_	VERB	_	VerbForm=Inf	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	viral	_	ADJ	_	Degree=Pos	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	signals	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	decrease	_	NOUN	_	Number=Sing	_	_	_	_
18	LTR	_	NOUN	_	Number=Sing	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
23	viral	_	ADJ	_	Degree=Pos	_	_	_	_
24	replication	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	5'-	_	NOUN	_	Number=Sing	_	_	_	_
3	UTR	_	PROPN	_	Number=Sing	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	nucleosome	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	rapidly	_	ADV	_	_	_	_	_	_
13	displaced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	during	_	ADP	_	_	_	_	_	_
15	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	latent	_	ADJ	_	Degree=Pos	_	_	_	_
20	provirus	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
9	sites	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	5'-	_	PUNCT	_	Number=Sing	_	_	_	_
13	UTR	_	PROPN	_	Number=Sing	_	_	_	_
14	comprise	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
17	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
18	domain	_	NOUN	_	Number=Sing	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	can	_	AUX	_	VerbForm=Fin	_	_	_	_
21	function	_	VERB	_	VerbForm=Inf	_	_	_	_
22	independent	_	ADJ	_	Degree=Pos	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	concert	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	LTR	_	PROPN	_	Number=Sing	_	_	_	_
32	promoter	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	rapidly	_	ADV	_	_	_	_	_	_
35	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
36	latent	_	ADJ	_	Degree=Pos	_	_	_	_
37	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	response	_	NOUN	_	Number=Sing	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	activation	_	NOUN	_	Number=Sing	_	_	_	_
44	signals	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	review	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	host	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	5'-	_	NOUN	_	Number=Sing	_	_	_	_
18	UTR	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	discuss	_	VERB	_	VerbForm=Inf	_	_	_	_
21	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
26	regulation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	HIV	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011303	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	M	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	CSF	_	PROPN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	M	_	NUM	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CSF	_	NOUN	_	Number=Sing	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	C	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	kappa	_	PROPN	_	Number=Sing	_	_	_	_
22	B.	_	PROPN	_	Number=Sing	_	_	_	_
23	Macrophage	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	colony	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	M	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	CSF	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	also	_	ADV	_	_	_	_	_	_
36	referred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	as	_	ADP	_	_	_	_	_	_
39	CSF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	survival	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	growth	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	functional	_	ADJ	_	Degree=Pos	_	_	_	_
52	activity	_	NOUN	_	Number=Sing	_	_	_	_
53	of	_	ADP	_	_	_	_	_	_
54	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
55	by	_	SCONJ	_	_	_	_	_	_
56	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
57	to	_	ADP	_	_	_	_	_	_
58	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
59	single	_	ADJ	_	Degree=Pos	_	_	_	_
60	class	_	NOUN	_	Number=Sing	_	_	_	_
61	of	_	ADP	_	_	_	_	_	_
62	high	_	ADJ	_	Degree=Pos	_	_	_	_
63	-	_	PUNCT	_	_	_	_	_	_
64	affinity	_	NOUN	_	Number=Sing	_	_	_	_
65	cell	_	NOUN	_	Number=Sing	_	_	_	_
66	surface	_	NOUN	_	Number=Sing	_	_	_	_
67	receptors	_	NOUN	_	Number=Plur	_	_	_	_
68	,	_	PUNCT	_	_	_	_	_	_
69	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
70	to	_	PART	_	_	_	_	_	_
71	be	_	AUX	_	VerbForm=Inf	_	_	_	_
72	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
73	product	_	NOUN	_	Number=Sing	_	_	_	_
74	of	_	ADP	_	_	_	_	_	_
75	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
76	c-fms	_	NOUN	_	Number=Plur	_	_	_	_
77	protooncogene	_	NOUN	_	Number=Sing	_	_	_	_
78	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	detection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	M	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	CSF	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	c-fms	_	NOUN	_	Number=Plur	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	lineage	_	NOUN	_	Number=Sing	_	_	_	_
17	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	M	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	CSF	_	PROPN	_	Number=Sing	_	_	_	_
23	may	_	AUX	_	VerbForm=Fin	_	_	_	_
24	act	_	VERB	_	VerbForm=Inf	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	autocrine	_	NOUN	_	Number=Sing	_	_	_	_
28	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
6	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	M	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CSF	_	PROPN	_	Number=Sing	_	_	_	_
11	can	_	AUX	_	VerbForm=Fin	_	_	_	_
12	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	own	_	ADJ	_	Degree=Pos	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	M	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	CSF	_	PROPN	_	Number=Sing	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	function	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	M	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	CSF	_	NOUN	_	Number=Sing	_	_	_	_
21	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	largely	_	ADV	_	_	_	_	_	_
24	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	at	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	postreceptor	_	NOUN	_	Number=Sing	_	_	_	_
28	level	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	To	_	ADP	_	_	_	_	_	_
2	date	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	little	_	ADV	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	about	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	pathway	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	M	_	NUM	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	CSF	_	NOUN	_	Number=Sing	_	_	_	_
15	signal	_	NOUN	_	Number=Sing	_	_	_	_
16	transduction	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	therefore	_	ADV	_	_	_	_	_	_
4	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	changes	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	C	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	PKC	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	upon	_	ADP	_	_	_	_	_	_
16	exposure	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	M	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	CSF	_	PROPN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	M-CSF	_	PROPN	_	Number=Sing	_	_	_	_
5	activates	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	translocates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	PKC	_	PROPN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	PKC	_	PROPN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	isoquinoline	_	ADJ	_	Number=Sing	_	_	_	_
7	derivative	_	NOUN	_	Number=Sing	_	_	_	_

1	H7	_	NOUN	_	Number=Sing	_	_	_	_
2	abolishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	M	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	CSF	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	M	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	CSF	_	PROPN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	PKC	_	PROPN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	pertussis	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	toxin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	detection	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	extracts	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	M	_	NUM	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	CSF	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	blood	_	NOUN	_	Number=Sing	_	_	_	_
34	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	but	_	CCONJ	_	_	_	_	_	_
36	not	_	ADV	_	_	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
39	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	medium	_	ADJ	_	Degree=Pos	_	_	_	_
42	treatment	_	NOUN	_	Number=Sing	_	_	_	_
43	only	_	ADV	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	M	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	CSF	_	NOUN	_	Number=Sing	_	_	_	_
8	induction	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	M	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	CSF	_	NOUN	_	Number=Sing	_	_	_	_
13	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	G	_	PROPN	_	Number=Sing	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	PKC	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	kappa	_	PROPN	_	Number=Sing	_	_	_	_
21	B.	_	PROPN	_	Number=Sing	_	_	_	_
22	Document	_	NOUN	_	Number=Sing	_	_	_	_
23	0030011305	_	NUM	_	NumType=Card	_	_	_	_
24	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	GATA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	non-lineage	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	silencer	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GATA	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	3	_	NUM	_	NumType=Card	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	development	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
14	lineage	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	CD4	_	PROPN	_	Number=Sing	_	_	_	_
22	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	mapped	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	DNase	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	I-hypersensitive	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HS	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	regions	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	GATA	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	3	_	NUM	_	NumType=Card	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	non-T	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	activities	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	HS	_	PROPN	_	Number=Sing	_	_	_	_
2	I-III	_	PROPN	_	NumType=Card	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	'	_	PUNCT	_	Number=Plur	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	initiation	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	non-hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whereas	_	SCONJ	_	_	_	_	_	_
22	HS	_	PROPN	_	Number=Sing	_	_	_	_
23	IV	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	VII	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	3	_	NUM	_	NumType=Card	_	_	_	_
29	'	_	PUNCT	_	_	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
33	start	_	NOUN	_	Number=Sing	_	_	_	_
34	site	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	exclusively	_	ADV	_	_	_	_	_	_
38	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	T-cells	_	PROPN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Among	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
4	sites	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	control	_	NOUN	_	Number=Sing	_	_	_	_
9	elements	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	one	_	NUM	_	NumType=Card	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
17	intron	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	GATA	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	3	_	NUM	_	NumType=Card	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	other	_	ADJ	_	Degree=Pos	_	_	_	_
27	between	_	ADP	_	_	_	_	_	_
28	8.3	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	5.9	_	NUM	_	NumType=Card	_	_	_	_
31	kilobases	_	NOUN	_	Number=Plur	_	_	_	_
32	5	_	NUM	_	NumType=Card	_	_	_	_
33	'	_	PUNCT	_	Number=Plur	_	_	_	_
34	from	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	GATA	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	3	_	NUM	_	NumType=Card	_	_	_	_
39	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
40	initiation	_	NOUN	_	Number=Sing	_	_	_	_
41	site	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	intron	_	NOUN	_	Number=Sing	_	_	_	_
4	acted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	strong	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	activator	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	position	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	manner	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	no	_	DET	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	type	_	NOUN	_	Number=Sing	_	_	_	_
22	specificity	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
3	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	element	_	NOUN	_	Number=Sing	_	_	_	_
5	could	_	AUX	_	VerbForm=Fin	_	_	_	_
6	confer	_	VERB	_	VerbForm=Inf	_	_	_	_
7	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
8	specificity	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	GATA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	3	_	NUM	_	NumType=Card	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	analysis	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	region	_	NOUN	_	Number=Sing	_	_	_	_
22	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	707	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	base	_	NOUN	_	Number=Sing	_	_	_	_
27	pair	_	NOUN	_	Number=Sing	_	_	_	_
28	silencer	_	NOUN	_	Number=Sing	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	drastically	_	ADV	_	_	_	_	_	_
31	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	GATA	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	3	_	NUM	_	NumType=Card	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	activity	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	non-T	_	ADJ	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	CAGGTG	_	NOUN	_	Number=Sing	_	_	_	_
3	E-boxes	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	5'-	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	'-	_	PUNCT	_	_	_	_	_	_
12	ends	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	silencer	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	silencer	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	3'-	_	NOUN	_	Number=Sing	_	_	_	_
3	CAGGTG	_	NOUN	_	Number=Sing	_	_	_	_
4	E-box	_	NOUN	_	Number=Sing	_	_	_	_
5	could	_	AUX	_	VerbForm=Fin	_	_	_	_
6	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
7	USF	_	PROPN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
12	repressor	_	NOUN	_	Number=Sing	_	_	_	_
13	ZEB	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	basic	_	ADJ	_	Degree=Pos	_	_	_	_
18	helix	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	loop	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	helix	_	NOUN	_	Number=Sing	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	E2A	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	HEB	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
30	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	competition	_	NOUN	_	Number=Sing	_	_	_	_
34	between	_	ADP	_	_	_	_	_	_
35	ZEB	_	PROPN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	E2A	_	PROPN	_	Number=Sing	_	_	_	_
38	/	_	PUNCT	_	_	_	_	_	_
39	HEB	_	NOUN	_	Number=Sing	_	_	_	_
40	proteins	_	NOUN	_	Number=Plur	_	_	_	_
41	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	involved	_	ADJ	_	Degree=Pos	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	silencer	_	NOUN	_	Number=Sing	_	_	_	_
46	activity	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011313	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Negative	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
3	regulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	interference	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	AP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	AT	_	NOUN	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	several	_	ADJ	_	Degree=Pos	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	asked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	Dex	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
10	A	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	CsA	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	SCONJ	_	_	_	_	_	_
21	interfering	_	VERB	_	VerbForm=Ger	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	proteins	_	NOUN	_	Number=Plur	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	extracts	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	primary	_	ADJ	_	Degree=Pos	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	mobility	_	NOUN	_	Number=Sing	_	_	_	_
14	shift	_	NOUN	_	Number=Sing	_	_	_	_
15	assays	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	Dex	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	CsA	_	PROPN	_	Number=Sing	_	_	_	_
5	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	AT	_	ADP	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	not	_	ADV	_	_	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kB	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	OCT	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1/OAF	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
32	corresponding	_	VERB	_	Degree=Pos	_	_	_	_
33	sites	_	NOUN	_	Number=Plur	_	_	_	_
34	on	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	promoter	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	To	_	ADP	_	_	_	_	_	_
2	correlate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	changes	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	vitro	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vivo	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	define	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	structural	_	ADJ	_	Degree=Pos	_	_	_	_
19	requirements	_	NOUN	_	Number=Plur	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	repression	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
28	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	transient	_	ADJ	_	Degree=Pos	_	_	_	_
30	DNA	_	NOUN	_	Number=Sing	_	_	_	_
31	transfections	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
7	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
8	either	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	intact	_	NOUN	_	Degree=Pos	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	AP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	AT	_	ADP	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kB	_	NOUN	_	Number=Sing	_	_	_	_
29	motifs	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Dex	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	AT	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kB	_	NOUN	_	Number=Sing	_	_	_	_
24	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	CsA	_	PROPN	_	Number=Sing	_	_	_	_
5	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	AT	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	not	_	ADV	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kB	_	NOUN	_	Number=Sing	_	_	_	_
27	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	Dex	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	CsA	_	PROPN	_	Number=Sing	_	_	_	_
13	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	through	_	ADP	_	_	_	_	_	_
20	interference	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	AP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	AT	_	NOUN	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	while	_	SCONJ	_	_	_	_	_	_
6	maximum	_	ADJ	_	Degree=Pos	_	_	_	_
7	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
10	interaction	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	AP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	primary	_	ADJ	_	Degree=Pos	_	_	_	_
22	target	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	Dex	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011325	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	ligand	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	domain	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	retinoic	_	ADJ	_	Number=Sing	_	_	_	_
11	acid	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Three	_	NUM	_	NumType=Card	_	_	_	_
2	subtypes	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
5	acid	_	NOUN	_	Number=Sing	_	_	_	_
6	receptors	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	RAR	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	RAR	_	PROPN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	RAR	_	PROPN	_	Number=Sing	_	_	_	_
16	beta	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	RAR	_	PROPN	_	Number=Sing	_	_	_	_
20	gamma	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	different	_	ADJ	_	Degree=Pos	_	_	_	_
6	structural	_	ADJ	_	Degree=Pos	_	_	_	_
7	domains	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	including	_	VERB	_	VerbForm=Ger	_	_	_	_
10	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
11	domains	_	NOUN	_	Number=Plur	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	DNA	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	ligand	_	NOUN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	RARs	_	NOUN	_	Number=Plur	_	_	_	_
2	specifically	_	ADV	_	_	_	_	_	_
3	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	all	_	DET	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	trans	_	NOUN	_	Number=Plur	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	retinoic	_	ADJ	_	Number=Sing	_	_	_	_
9	acid	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	RA	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	9-cis	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	RA	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	retinoid	_	ADJ	_	Number=Sing	_	_	_	_
20	analogs	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	functional	_	ADJ	_	Degree=Pos	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	arginine	_	VERB	_	Number=Sing	_	_	_	_
14	residues	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	ligand	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	binding	_	VERB	_	Number=Sing	_	_	_	_
20	domain	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	hRAR	_	NOUN	_	Number=Sing	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	hRAR	_	PROPN	_	Number=Sing	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	LBD	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	amino	_	PROPN	_	Number=Sing	_	_	_	_
31	acids	_	NOUN	_	Number=Plur	_	_	_	_
32	154	_	NUM	_	NumType=Card	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	462	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	conserved	_	VERB	_	Degree=Pos	_	_	_	_
3	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	arginine	_	VERB	_	Number=Sing	_	_	_	_
6	residues	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	domain	_	NOUN	_	Number=Sing	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	mutated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	mutant	_	ADJ	_	Number=Sing	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	blocking	_	NOUN	_	VerbForm=Ger	_	_	_	_
26	reactions	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	ligand	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	binding	_	VERB	_	Number=Sing	_	_	_	_
31	experiments	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
34	assays	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	protease	_	NOUN	_	Number=Sing	_	_	_	_
38	mapping	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Changes	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	any	_	DET	_	_	_	_	_	_
4	cysteine	_	NOUN	_	Degree=Pos	_	_	_	_
5	residue	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	hRAR	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha-LBD	_	PROPN	_	Number=Sing	_	_	_	_
10	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	no	_	DET	_	_	_	_	_	_
12	significant	_	ADJ	_	Degree=Pos	_	_	_	_
13	influence	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	all	_	DET	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	trans	_	NOUN	_	Number=Sing	_	_	_	_
21	RA	_	NOUN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	9-cis	_	PROPN	_	Number=Sing	_	_	_	_
24	RA	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	residue	_	PROPN	_	Number=Sing	_	_	_	_
4	C	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	235	_	NUM	_	NumType=Card	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	specifically	_	ADV	_	_	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	antagonist	_	ADJ	_	Number=Sing	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	With	_	ADP	_	_	_	_	_	_
2	respect	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	arginine	_	VERB	_	VerbForm=Inf	_	_	_	_
5	residues	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	only	_	ADV	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	single	_	ADJ	_	Degree=Pos	_	_	_	_
11	mutations	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	R	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	276	_	NUM	_	NumType=Card	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	R-394	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	alanine	_	NOUN	_	Number=Sing	_	_	_	_
20	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
23	decrease	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	agonist	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	antagonist	_	ADJ	_	Number=Sing	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	whereas	_	SCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	R272A	_	PROPN	_	Number=Sing	_	_	_	_
32	mutation	_	NOUN	_	Number=Sing	_	_	_	_
33	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	only	_	ADV	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	slight	_	ADJ	_	Degree=Pos	_	_	_	_
37	effect	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	all	_	DET	_	_	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	arginine	_	NOUN	_	Number=Sing	_	_	_	_
5	mutations	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	no	_	DET	_	_	_	_	_	_
8	differences	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	affinity	_	NOUN	_	Number=Sing	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	mutations	_	NOUN	_	Number=Plur	_	_	_	_
4	R217A	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	R294A	_	PROPN	_	Number=Sing	_	_	_	_
7	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	binding	_	NOUN	_	Degree=Pos	_	_	_	_
11	efficiency	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	antagonists	_	NOUN	_	Number=Plur	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	no	_	DET	_	_	_	_	_	_
16	change	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	agonist	_	ADJ	_	Degree=Pos	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	From	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	results	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	conclude	_	VERB	_	VerbForm=Inf	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	electrostatic	_	ADJ	_	Degree=Pos	_	_	_	_
10	interactions	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	retinoids	_	NOUN	_	Number=Plur	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	RAR	_	PROPN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	LBD	_	PROPN	_	Number=Sing	_	_	_	_
19	play	_	VERB	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	significant	_	ADJ	_	Degree=Pos	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	ligand	_	NOUN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	antagonists	_	NOUN	_	Number=Plur	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	distinctly	_	ADV	_	_	_	_	_	_
7	different	_	ADJ	_	Degree=Pos	_	_	_	_
8	requirements	_	NOUN	_	Number=Plur	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	interference	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	ligand	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
24	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
25	function	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	RAR	_	NOUN	_	Number=Sing	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011326	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	Rel	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	A	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	c	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	Rel	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	complexes	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	differentially	_	ADV	_	_	_	_	_	_
13	distributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	within	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	Rel	_	NOUN	_	Number=Sing	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	regulators	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	numerous	_	ADJ	_	Degree=Pos	_	_	_	_
21	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	particularly	_	ADV	_	_	_	_	_	_
4	abundant	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
7	tissues	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	critical	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	involved	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	immune	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	responses	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	previously	_	ADV	_	_	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	NF	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	present	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	freshly	_	ADV	_	_	_	_	_	_
17	extracted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	absence	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	vitro	_	NOUN	_	Number=Sing	_	_	_	_
26	treatment	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	report	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	PROPN	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	extracted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	thymocyte	_	NOUN	_	Number=Sing	_	_	_	_
17	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
18	as	_	SCONJ	_	_	_	_	_	_
19	being	_	AUX	_	VerbForm=Ger	_	_	_	_
20	p50/p65	_	NUM	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	p50/c	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	Rel	_	NOUN	_	Number=Sing	_	_	_	_
25	complexes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Immunochemical	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	immunofluorescent	_	ADJ	_	Degree=Pos	_	_	_	_
4	staining	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	thymus	_	ADJ	_	Degree=Pos	_	_	_	_
7	sections	_	NOUN	_	Number=Plur	_	_	_	_
8	using	_	VERB	_	VerbForm=Ger	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	Abs	_	NOUN	_	Number=Sing	_	_	_	_
11	allowed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	visualization	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	NF	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	both	_	CCONJ	_	_	_	_	_	_
22	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	nonthymocyte	_	NOUN	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	detection	_	NOUN	_	Number=Sing	_	_	_	_
3	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	preferential	_	ADJ	_	Degree=Pos	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	p50/c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	Rel	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	medullary	_	ADJ	_	Degree=Pos	_	_	_	_
13	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	whereas	_	SCONJ	_	_	_	_	_	_
16	p50/p65	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	present	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	cortical	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	medullary	_	ADJ	_	Degree=Pos	_	_	_	_
24	regions	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	thymus	_	NOUN	_	Number=Sing	_	_	_	_
28	lobules	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	intensity	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	p65	_	NOUN	_	Number=Sing	_	_	_	_
7	labeling	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	much	_	ADV	_	_	_	_	_	_
10	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	several	_	ADJ	_	Degree=Pos	_	_	_	_
13	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	medulla	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	p65	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	p50	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
7	activities	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	CD4	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	CD8	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	positive	_	ADJ	_	Degree=Pos	_	_	_	_
18	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	p65	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
8	complexes	_	NOUN	_	Number=Plur	_	_	_	_
9	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
11	roles	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	both	_	DET	_	_	_	_	_	_
18	forms	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	play	_	VERB	_	VerbForm=Inf	_	_	_	_
25	critical	_	ADJ	_	Degree=Pos	_	_	_	_
26	roles	_	NOUN	_	Number=Plur	_	_	_	_
27	during	_	ADP	_	_	_	_	_	_
28	late	_	ADJ	_	Degree=Pos	_	_	_	_
29	stages	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	intrathymic	_	ADJ	_	Degree=Pos	_	_	_	_
33	maturation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	T	_	NOUN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011328	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Abundant	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	P45	_	NUM	_	Number=Sing	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	E2	_	NUM	_	Number=Sing	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
15	granurocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	E2	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	regulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	p45	_	NUM	_	Number=Sing	_	_	_	_
2	subunit	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	E2	_	PROPN	_	Number=Sing	_	_	_	_
7	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	basic	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	leucine	_	NOUN	_	Number=Sing	_	_	_	_
12	zipper	_	NOUN	_	Number=Sing	_	_	_	_
13	domain	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	dimerizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	small	_	ADJ	_	Degree=Pos	_	_	_	_
19	Maf	_	NOUN	_	Number=Sing	_	_	_	_
20	family	_	NOUN	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	form	_	VERB	_	VerbForm=Inf	_	_	_	_
24	functional	_	ADJ	_	Degree=Pos	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	E2	_	PROPN	_	Number=Sing	_	_	_	_
28	complex	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	p45	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	megakaryocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	mast	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
19	lineage	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
22	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	study	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	PRON	_	_	_	_	_	_
27	p45	_	PROPN	_	Number=Sing	_	_	_	_
28	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	abundantly	_	ADV	_	_	_	_	_	_
31	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
35	fraction	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	human	_	ADJ	_	Degree=Pos	_	_	_	_
38	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
39	blood	_	NOUN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
3	occupy	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	approximately	_	ADV	_	_	_	_	_	_
5	92	_	NUM	_	NumType=Card	_	_	_	_
6	%	_	SYM	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
12	fraction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
16	blood	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
3	occupy	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	approximately	_	ADV	_	_	_	_	_	_
5	92	_	NUM	_	NumType=Card	_	_	_	_
6	%	_	SYM	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
12	fraction	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	p45	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	most	_	ADV	_	_	_	_	_	_
20	likely	_	ADJ	_	Degree=Pos	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	p45	_	NOUN	_	Number=Sing	_	_	_	_
2	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	HL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	60	_	NUM	_	NumType=Card	_	_	_	_
10	promyelocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	albeit	_	SCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	much	_	ADV	_	_	_	_	_	_
18	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
19	than	_	ADP	_	_	_	_	_	_
20	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
24	fraction	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	HL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	60	_	NUM	_	NumType=Card	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	express	_	VERB	_	Degree=Pos	_	_	_	_
9	mafK	_	ADJ	_	Degree=Pos	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	presence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	genuine	_	ADJ	_	Degree=Pos	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	E2	_	NOUN	_	Number=Sing	_	_	_	_
20	complex	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	p45	_	PROPN	_	Number=Sing	_	_	_	_
3	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	different	_	ADJ	_	Degree=Pos	_	_	_	_
9	promoters	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	aNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	E2	_	PROPN	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	fNF	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	E2	_	PROPN	_	Number=Sing	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	lineage	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	p45	_	NOUN	_	Number=Sing	_	_	_	_
29	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	only	_	ADV	_	_	_	_	_	_
33	from	_	ADP	_	_	_	_	_	_
34	aNF	_	DET	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	E2	_	PROPN	_	Number=Sing	_	_	_	_
37	promoter	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p45	_	NUM	_	Number=Sing	_	_	_	_
5	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
6	lineage	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	p45	_	NOUN	_	Number=Sing	_	_	_	_
10	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	only	_	ADV	_	_	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	aNF	_	DET	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	E2	_	PROPN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p45	_	NOUN	_	Number=Sing	_	_	_	_
5	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
9	declined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	rapidly	_	ADV	_	_	_	_	_	_
11	after	_	ADP	_	_	_	_	_	_
12	transfer	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	vitro	_	ADJ	_	Degree=Pos	_	_	_	_
19	culture	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	G	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	CSF	_	NOUN	_	Number=Sing	_	_	_	_
24	could	_	AUX	_	VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	sustain	_	VERB	_	VerbForm=Inf	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	down	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	regulation	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	E2	_	NOUN	_	Number=Sing	_	_	_	_
38	may	_	AUX	_	VerbForm=Fin	_	_	_	_
39	also	_	ADV	_	_	_	_	_	_
40	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	regulation	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	specific	_	ADJ	_	Degree=Pos	_	_	_	_
48	gene	_	NOUN	_	Number=Sing	_	_	_	_
49	expression	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011338	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	CD40	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	critical	_	ADJ	_	Degree=Pos	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	CD40	_	PROPN	_	Number=Sing	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	B	_	ADJ	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	CD40	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	critical	_	ADJ	_	Degree=Pos	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	survival	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	isotype	_	NOUN	_	Number=Sing	_	_	_	_
18	switching	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	CD40	_	PROPN	_	Number=Sing	_	_	_	_
3	lacks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	intrinsic	_	ADJ	_	Degree=Pos	_	_	_	_
5	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	ligation	_	NOUN	_	Number=Sing	_	_	_	_
11	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
14	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	several	_	ADJ	_	Degree=Pos	_	_	_	_
21	CD40	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
24	events	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	engagement	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CD40	_	PROPN	_	Number=Sing	_	_	_	_
7	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	tyrosine	_	NOUN	_	Degree=Pos	_	_	_	_
9	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
14	as	_	ADV	_	_	_	_	_	_
15	well	_	ADV	_	Degree=Pos	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	constitutively	_	ADV	_	_	_	_	_	_
4	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	CD40	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	interaction	_	NOUN	_	Number=Sing	_	_	_	_
11	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	proline	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	rich	_	ADJ	_	Degree=Pos	_	_	_	_
16	sequence	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	membrane	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
22	region	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	CD40	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	sequence	_	NOUN	_	Number=Sing	_	_	_	_
5	abolishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	capacity	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	CD40	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	CD23	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	lymphotoxin	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	alpha	_	ADJ	_	Number=Sing	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	B	_	ADJ	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
6	through	_	ADP	_	_	_	_	_	_
7	Jak3	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	CD40	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	important	_	ADJ	_	Degree=Pos	_	_	_	_
16	role	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	CD40	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
21	functions	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011339	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Thymocyte	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
4	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	interaction	_	NOUN	_	Number=Sing	_	_	_	_
7	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	high	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	level	_	NOUN	_	Number=Sing	_	_	_	_
12	replication	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	exclusively	_	ADV	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	mature	_	ADJ	_	Degree=Pos	_	_	_	_
20	CD4	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	+	_	SYM	_	_	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	CD8	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	-)	_	PUNCT	_	_	_	_	_	_
27	CD3	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	+	_	SYM	_	_	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	:	_	PUNCT	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	critical	_	ADJ	_	Degree=Pos	_	_	_	_
35	role	_	NOUN	_	Number=Sing	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	tumor	_	NOUN	_	Number=Sing	_	_	_	_
38	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
39	factor	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	7	_	NUM	_	NumType=Card	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	work	_	NOUN	_	Number=Sing	_	_	_	_
3	aims	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	at	_	SCONJ	_	_	_	_	_	_
5	identifying	_	VERB	_	VerbForm=Ger	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	thymocyte	_	NOUN	_	Number=Sing	_	_	_	_
8	subpopulation	_	NOUN	_	Number=Sing	_	_	_	_
9	able	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	support	_	VERB	_	VerbForm=Inf	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	replication	_	NOUN	_	Number=Sing	_	_	_	_
19	under	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	biological	_	ADJ	_	Degree=Pos	_	_	_	_
22	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
26	microenvironment	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	interaction	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
10	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	TEC	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	high	_	ADJ	_	Degree=Pos	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	level	_	NOUN	_	Number=Sing	_	_	_	_
20	replication	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	T-tropic	_	ADJ	_	Degree=Pos	_	_	_	_
24	primary	_	ADJ	_	Degree=Pos	_	_	_	_
25	isolate	_	NOUN	_	Number=Sing	_	_	_	_
26	HIV	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	LAIp	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	exclusively	_	ADV	_	_	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	mature	_	ADJ	_	Degree=Pos	_	_	_	_
38	CD4	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	+	_	SYM	_	_	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	CD8	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	-)	_	PUNCT	_	_	_	_	_	_
45	CD3	_	NOUN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	+	_	SYM	_	_	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	TNF	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	7	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	7	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	secreted	_	VERB	_	Degree=Pos	_	_	_	_
18	during	_	ADP	_	_	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	interaction	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	critical	_	ADJ	_	Degree=Pos	_	_	_	_
24	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	HIV	_	PROPN	_	Number=Sing	_	_	_	_
27	long	_	ADJ	_	Degree=Pos	_	_	_	_
28	terminal	_	NOUN	_	Number=Sing	_	_	_	_
29	repeat	_	NOUN	_	Number=Sing	_	_	_	_
30	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
31	through	_	ADP	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	major	_	ADJ	_	Degree=Pos	_	_	_	_
5	inducer	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	particularly	_	ADV	_	_	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	p50-p65	_	NUM	_	Number=Sing	_	_	_	_
15	complex	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	whereas	_	SCONJ	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	7	_	NUM	_	NumType=Card	_	_	_	_
21	acts	_	NOUN	_	Number=Plur	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	cofactor	_	NOUN	_	Number=Sing	_	_	_	_
25	by	_	SCONJ	_	_	_	_	_	_
26	sustaining	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	p75	_	NOUN	_	Number=Sing	_	_	_	_
32	TNF	_	NOUN	_	Number=Sing	_	_	_	_
33	receptor	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	requirement	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	further	_	ADV	_	_	_	_	_	_
7	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	observation	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	inability	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	intermediate	_	ADJ	_	Degree=Pos	_	_	_	_
17	CD4	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	CD8	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	-)	_	PUNCT	_	_	_	_	_	_
24	CD3	_	PROPN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	virus	_	NOUN	_	Number=Sing	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	defect	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	TNF	_	NOUN	_	Number=Sing	_	_	_	_
40	production	_	NOUN	_	Number=Sing	_	_	_	_
41	during	_	ADP	_	_	_	_	_	_
42	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
43	interaction	_	NOUN	_	Number=Sing	_	_	_	_
44	with	_	ADP	_	_	_	_	_	_
45	TEC	_	PROPN	_	Number=Sing	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
48	with	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	absence	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
53	NF	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
56	activity	_	NOUN	_	Number=Sing	_	_	_	_
57	in	_	ADP	_	_	_	_	_	_
58	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
59	freshly	_	ADV	_	_	_	_	_	_
60	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
61	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	Addition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
4	TNF	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	intermediate	_	ADJ	_	Degree=Pos	_	_	_	_
8	thymocyte	_	NOUN	_	Number=Sing	_	_	_	_
9	cultures	_	NOUN	_	Number=Plur	_	_	_	_
10	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	replication	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	cocultures	_	NOUN	_	Number=Plur	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	TEC	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	major	_	ADJ	_	Degree=Pos	_	_	_	_
4	subpopulation	_	NOUN	_	Number=Sing	_	_	_	_
5	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	CD4	_	PROPN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	namely	_	ADV	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	double	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	positive	_	ADJ	_	Degree=Pos	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	DP	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	CD4	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	+	_	SYM	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	CD8	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	+	_	SYM	_	_	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	CD3	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	+/-	_	SYM	_	_	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	despite	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	entry	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	virus	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
41	not	_	PART	_	_	_	_	_	_
42	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	significant	_	ADJ	_	Degree=Pos	_	_	_	_
45	level	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	virus	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	presumably	_	ADV	_	_	_	_	_	_
50	because	_	SCONJ	_	_	_	_	_	_
51	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
52	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
53	unresponsive	_	ADJ	_	Degree=Pos	_	_	_	_
54	to	_	ADP	_	_	_	_	_	_
55	TNF	_	PROPN	_	Number=Sing	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	IL	_	PROPN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	7	_	NUM	_	NumType=Card	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	vivo	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	despite	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
13	entry	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	all	_	DET	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	CD4	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	+	_	SYM	_	_	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	subpopulations	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	high	_	ADJ	_	Degree=Pos	_	_	_	_
28	viral	_	ADJ	_	Degree=Pos	_	_	_	_
29	load	_	NOUN	_	Number=Sing	_	_	_	_
30	may	_	AUX	_	VerbForm=Fin	_	_	_	_
31	be	_	AUX	_	VerbForm=Inf	_	_	_	_
32	generated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	exclusively	_	ADV	_	_	_	_	_	_
34	within	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	mature	_	ADJ	_	Degree=Pos	_	_	_	_
37	CD4	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	+	_	SYM	_	_	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	CD8	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	-)	_	PUNCT	_	_	_	_	_	_
44	CD3	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	+	_	SYM	_	_	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	subset	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	under	_	ADP	_	_	_	_	_	_
4	conditions	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	after	_	ADP	_	_	_	_	_	_
9	infection	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	might	_	AUX	_	VerbForm=Fin	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	present	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	intermediate	_	ADJ	_	Degree=Pos	_	_	_	_
19	thymocyte	_	NOUN	_	Number=Sing	_	_	_	_
20	compartment	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	replication	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011340	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CD95	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	Fas	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	ligand	_	NOUN	_	Degree=Pos	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	TCR	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	mediated	_	VERB	_	Degree=Pos	_	_	_	_
13	signaling	_	NOUN	_	Number=Sing	_	_	_	_
14	events	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	mature	_	ADJ	_	Degree=Pos	_	_	_	_
4	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	TCR	_	NOUN	_	Number=Sing	_	_	_	_
9	engagement	_	NOUN	_	Number=Sing	_	_	_	_
10	results	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	signals	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	drive	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
24	expansion	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	under	_	ADP	_	_	_	_	_	_
4	some	_	DET	_	_	_	_	_	_
5	conditions	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	engagement	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	TCR	_	NOUN	_	Number=Sing	_	_	_	_
11	leads	_	NOUN	_	Number=Plur	_	_	_	_
12	instead	_	ADV	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TCR	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
9	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	CD95	_	PROPN	_	Number=Sing	_	_	_	_
13	ligand	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	interaction	_	NOUN	_	Number=Sing	_	_	_	_
22	between	_	ADP	_	_	_	_	_	_
23	CD95	_	PROPN	_	Number=Sing	_	_	_	_
24	ligand	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	CD95	_	PROPN	_	Number=Sing	_	_	_	_
28	receptor	_	NOUN	_	Number=Sing	_	_	_	_
29	also	_	ADV	_	_	_	_	_	_
30	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	on	_	ADP	_	_	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	population	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	study	_	NOUN	_	Number=Sing	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	designed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	address	_	VERB	_	VerbForm=Inf	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	signaling	_	NOUN	_	Number=Sing	_	_	_	_
13	events	_	NOUN	_	Number=Plur	_	_	_	_
14	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	TCR	_	NOUN	_	Number=Sing	_	_	_	_
17	engagement	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	important	_	ADJ	_	Degree=Pos	_	_	_	_
21	for	_	SCONJ	_	_	_	_	_	_
22	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	CD95	_	PROPN	_	Number=Sing	_	_	_	_
24	ligand	_	NOUN	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	approach	_	VERB	_	VerbForm=Inf	_	_	_	_
3	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	generated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
9	reporter	_	NOUN	_	Number=Sing	_	_	_	_
10	construct	_	NOUN	_	Number=Sing	_	_	_	_
11	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	elements	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	CD95	_	PROPN	_	Number=Sing	_	_	_	_
16	ligand	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	mutant	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
17	signaling	_	NOUN	_	Number=Sing	_	_	_	_
18	events	_	NOUN	_	Number=Plur	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	presence	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	CD45	_	PROPN	_	Number=Sing	_	_	_	_
26	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
27	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	TCR	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	CD95	_	PROPN	_	Number=Sing	_	_	_	_
35	ligand	_	NOUN	_	Number=Sing	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	further	_	ADV	_	_	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	TCR	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	Ras	_	PROPN	_	Number=Sing	_	_	_	_
14	signaling	_	NOUN	_	Number=Sing	_	_	_	_
15	pathway	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	CD95	_	PROPN	_	Number=Sing	_	_	_	_
23	ligand	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Next	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	effort	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
8	critical	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	CD95	_	PROPN	_	Number=Sing	_	_	_	_
14	ligand	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
18	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
21	A	_	NOUN	_	Definite=Ind|PronType=Art	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	AT	_	ADP	_	_	_	_	_	_
28	response	_	NOUN	_	Number=Sing	_	_	_	_
29	element	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	promoter	_	ADJ	_	Number=Sing	_	_	_	_
33	region	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	that	_	PRON	_	PronType=Rel	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	critical	_	ADJ	_	Degree=Pos	_	_	_	_
40	for	_	ADP	_	_	_	_	_	_
41	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
42	CD95	_	PROPN	_	Number=Sing	_	_	_	_
43	ligand	_	NOUN	_	Number=Sing	_	_	_	_
44	reporter	_	NOUN	_	Number=Sing	_	_	_	_
45	activity	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	T	_	PROPN	_	Number=Sing	_	_	_	_
49	cells	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	begin	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	dissection	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
11	events	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	CD95	_	PROPN	_	Number=Sing	_	_	_	_
18	ligand	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	step	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	TCR	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011342	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Involvement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Egr	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1/RelA	_	PROPN	_	Number=Sing	_	_	_	_
6	synergy	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	distinguishing	_	ADJ	_	Degree=Pos	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	tumor	_	NOUN	_	Number=Sing	_	_	_	_
14	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B1	_	NOUN	_	Number=Sing	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	important	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	T	_	NUM	_	NumType=Card	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	other	_	ADJ	_	Degree=Pos	_	_	_	_
17	immunological	_	ADJ	_	Degree=Pos	_	_	_	_
18	functions	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B1	_	PROPN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	105	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kD	_	NOUN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	precursor	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	p50	_	NUM	_	Number=Sing	_	_	_	_
20	component	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	PROPN	_	Number=Sing	_	_	_	_
25	B.	_	PROPN	_	Number=Sing	_	_	_	_
26	Previously	_	ADV	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	others	_	NOUN	_	Number=Plur	_	_	_	_
31	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	that	_	SCONJ	_	_	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappa	_	PROPN	_	Number=Sing	_	_	_	_
37	B	_	PROPN	_	Number=Sing	_	_	_	_
38	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappa	_	NOUN	_	Number=Sing	_	_	_	_
43	B1	_	NOUN	_	Number=Sing	_	_	_	_
44	gene	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	manuscript	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
9	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	lines	_	NOUN	_	Number=Plur	_	_	_	_
15	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
18	12	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	myristate	_	NOUN	_	Number=Sing	_	_	_	_
21	13	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	acetate	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	PMA	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	phytohemagglutin	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	PHA	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	display	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	significantly	_	ADV	_	_	_	_	_	_
34	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
35	levels	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kappa	_	NOUN	_	Number=Sing	_	_	_	_
40	B1	_	NOUN	_	Number=Sing	_	_	_	_
41	encoding	_	NOUN	_	Number=Sing	_	_	_	_
42	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
43	than	_	ADP	_	_	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	with	_	ADP	_	_	_	_	_	_
47	tumor	_	NOUN	_	Number=Sing	_	_	_	_
48	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
49	factor	_	NOUN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	alpha	_	NOUN	_	Number=Sing	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	despite	_	ADP	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	fact	_	NOUN	_	Number=Sing	_	_	_	_
56	that	_	SCONJ	_	_	_	_	_	_
57	both	_	DET	_	_	_	_	_	_
58	stimuli	_	ADV	_	Degree=Pos	_	_	_	_
59	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
60	NF	_	PROPN	_	Number=Sing	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	kappa	_	PROPN	_	Number=Sing	_	_	_	_
63	B.	_	PROPN	_	Number=Sing	_	_	_	_
64	Characterization	_	PROPN	_	Number=Sing	_	_	_	_
65	of	_	ADP	_	_	_	_	_	_
66	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
67	NF	_	PROPN	_	Number=Sing	_	_	_	_
68	-	_	PUNCT	_	_	_	_	_	_
69	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B1	_	PROPN	_	Number=Sing	_	_	_	_
2	promoter	_	NOUN	_	Number=Sing	_	_	_	_
3	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	Egr	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	essential	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	both	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	PMA	_	PROPN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	PHA	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	induction	_	NOUN	_	Number=Sing	_	_	_	_
24	as	_	ADV	_	_	_	_	_	_
25	well	_	ADV	_	Degree=Pos	_	_	_	_
26	as	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	after	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	RelA	_	PROPN	_	Number=Sing	_	_	_	_
37	subunit	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappa	_	PROPN	_	Number=Sing	_	_	_	_
42	B	_	NOUN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	Egr	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Egr	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B1	_	NUM	_	Degree=Pos	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	since	_	ADP	_	_	_	_	_	_
6	PMA	_	PROPN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	PHA	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	lines	_	NOUN	_	Number=Plur	_	_	_	_
14	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	antisense	_	ADJ	_	Degree=Pos	_	_	_	_
16	Egr	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	RNA	_	PROPN	_	Number=Sing	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	ability	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	upregulate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B1	_	NOUN	_	Number=Sing	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	synergy	_	NOUN	_	Number=Sing	_	_	_	_
7	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	Egr	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	have	_	VERB	_	VerbForm=Inf	_	_	_	_
22	important	_	ADJ	_	Degree=Pos	_	_	_	_
23	ramifications	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	T	_	PROPN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	development	_	NOUN	_	Number=Sing	_	_	_	_
28	by	_	SCONJ	_	_	_	_	_	_
29	upregulating	_	VERB	_	VerbForm=Ger	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B1	_	PROPN	_	Number=Sing	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011345	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	AP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	import	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	noninvasive	_	ADJ	_	Degree=Pos	_	_	_	_
23	delivery	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	peptide	_	NOUN	_	Number=Sing	_	_	_	_
26	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	localization	_	NOUN	_	Number=Sing	_	_	_	_
30	sequence	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappa	_	NOUN	_	Number=Sing	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	p50	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	Ags	_	NOUN	_	Number=Sing	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
9	results	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	translocation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	AP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	STAT	_	NOUN	_	Number=Sing	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
32	into	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	step	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	import	_	NOUN	_	Number=Sing	_	_	_	_
8	process	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	recognition	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	localization	_	NOUN	_	Number=Sing	_	_	_	_
15	sequence	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	NLS	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	within	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	karyophilic	_	ADJ	_	Number=Sing	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	such	_	ADJ	_	Degree=Pos	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	importin	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	karyopherin	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	alpha	_	NOUN	_	Number=Sing	_	_	_	_
36	subunit	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NLSs	_	PROPN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	PROPN	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	AP	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
15	differ	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	NLS	_	PROPN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
21	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	yet	_	ADV	_	_	_	_	_	_
24	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
25	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Herein	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	import	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
25	T	_	PROPN	_	Number=Sing	_	_	_	_
26	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	significantly	_	ADV	_	_	_	_	_	_
29	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	permeable	_	ADJ	_	Degree=Pos	_	_	_	_
35	peptide	_	NOUN	_	Number=Sing	_	_	_	_
36	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	NLS	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	NF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	kappa	_	NOUN	_	Number=Sing	_	_	_	_
44	B	_	PROPN	_	Number=Sing	_	_	_	_
45	p50	_	PROPN	_	Number=Sing	_	_	_	_
46	subunit	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	NLS	_	PROPN	_	Number=Sing	_	_	_	_
2	peptide	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	mediated	_	VERB	_	Degree=Pos	_	_	_	_
5	disruption	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	import	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	results	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	kappa	_	VERB	_	Number=Sing	_	_	_	_
20	B	_	PROPN	_	Number=Sing	_	_	_	_
21	alpha	_	PROPN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	processes	_	NOUN	_	Number=Plur	_	_	_	_
30	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
31	on	_	ADP	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappa	_	PROPN	_	Number=Sing	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	or	_	CCONJ	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	combination	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappa	_	PROPN	_	Number=Sing	_	_	_	_
43	B	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	AP	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
7	NLS	_	PROPN	_	Number=Sing	_	_	_	_
8	peptide	_	NOUN	_	Number=Sing	_	_	_	_
9	interacts	_	VERB	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	vitro	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
15	NLS	_	PROPN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	complex	_	NOUN	_	Number=Sing	_	_	_	_
18	comprised	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	Rch1	_	PROPN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	importin	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	karyopherin	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	beta	_	NOUN	_	Number=Sing	_	_	_	_
29	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
30	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
33	T	_	NOUN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	import	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
28	T	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	can	_	AUX	_	VerbForm=Fin	_	_	_	_
31	be	_	AUX	_	VerbForm=Inf	_	_	_	_
32	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	NLS	_	PROPN	_	Number=Sing	_	_	_	_
35	peptide	_	NOUN	_	Number=Sing	_	_	_	_
36	delivered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	noninvasively	_	ADV	_	_	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
43	T	_	PROPN	_	Number=Sing	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	to	_	PART	_	_	_	_	_	_
46	target	_	VERB	_	VerbForm=Inf	_	_	_	_
47	members	_	NOUN	_	Number=Plur	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	importin	_	NOUN	_	Number=Sing	_	_	_	_
51	(	_	PUNCT	_	_	_	_	_	_
52	karyopherin	_	NOUN	_	Number=Sing	_	_	_	_
53	)	_	PUNCT	_	_	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	alpha	_	PROPN	_	Number=Sing	_	_	_	_
56	beta	_	NOUN	_	Number=Sing	_	_	_	_
57	NLS	_	PROPN	_	Number=Sing	_	_	_	_
58	receptor	_	NOUN	_	Number=Sing	_	_	_	_
59	complex	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011346	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	GATA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	differentially	_	ADV	_	_	_	_	_	_
8	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	murine	_	NOUN	_	Number=Sing	_	_	_	_
11	Th1	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	controls	_	VERB	_	Number=Plur	_	_	_	_
17	Th2	_	ADJ	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	5	_	NUM	_	NumType=Card	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-5	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	CD4	_	PROPN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	+)	_	SYM	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	helper	_	NOUN	_	Number=Sing	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	Th2	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	key	_	ADJ	_	Degree=Pos	_	_	_	_
32	role	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	development	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	eosinophilia	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	asthma	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Despite	_	ADP	_	_	_	_	_	_
2	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	evidence	_	NOUN	_	Number=Sing	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	outcome	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	many	_	ADJ	_	Degree=Pos	_	_	_	_
9	diseases	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	ratio	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	subsets	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	CD4	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	+)	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	helper	_	VERB	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	Th1	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	Th2	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
11	basis	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	Th1	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	Th2	_	ADJ	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	elucidated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	established	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	critical	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	GATA	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	3	_	NUM	_	NumType=Card	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	5	_	NUM	_	NumType=Card	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	EL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	4	_	NUM	_	NumType=Card	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	which	_	PRON	_	PronType=Rel	_	_	_	_
27	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	both	_	CCONJ	_	_	_	_	_	_
29	Th1	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	Th2	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	type	_	NOUN	_	Number=Sing	_	_	_	_
35	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	here	_	ADV	_	PronType=Dem	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	GATA	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	critical	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	5	_	NUM	_	NumType=Card	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	bona	_	NOUN	_	Number=Sing	_	_	_	_
22	fide	_	NOUN	_	Number=Sing	_	_	_	_
23	Th2	_	DET	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	mutations	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	GATA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	3	_	NUM	_	NumType=Card	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	antigen	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	5	_	NUM	_	NumType=Card	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	GATA	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	non-lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	non-IL	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	5	_	NUM	_	NumType=Card	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
44	cell	_	NOUN	_	Number=Sing	_	_	_	_
45	line	_	NOUN	_	Number=Sing	_	_	_	_
46	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	IL	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	5	_	NUM	_	NumType=Card	_	_	_	_
51	promoter	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	During	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	naive	_	ADJ	_	Degree=Pos	_	_	_	_
6	CD4	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	+)	_	SYM	_	_	_	_	_	_

1	T	_	NUM	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	transgenic	_	ADJ	_	Number=Sing	_	_	_	_
9	mice	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	GATA	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	3	_	NUM	_	NumType=Card	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	up	_	ADV	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	SCONJ	_	_	_	_	_	_
21	developing	_	VERB	_	VerbForm=Ger	_	_	_	_

1	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	but	_	CCONJ	_	_	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	down	_	ADV	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	antigen	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	not	_	ADV	_	_	_	_	_	_
25	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	GATA	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	3	_	NUM	_	NumType=Card	_	_	_	_
33	protein	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	GATA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	play	_	VERB	_	VerbForm=Inf	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	balance	_	NOUN	_	Number=Sing	_	_	_	_
14	between	_	ADP	_	_	_	_	_	_
15	Th1	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	Th2	_	DET	_	Number=Sing	_	_	_	_
18	subsets	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	immune	_	ADJ	_	Degree=Pos	_	_	_	_
21	responses	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	GATA	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
9	potential	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	treatment	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	asthma	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	other	_	ADJ	_	Degree=Pos	_	_	_	_
17	hypereosinophilic	_	ADJ	_	Degree=Pos	_	_	_	_
18	diseases	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011359	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	replication	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vitro	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	novel	_	NOUN	_	Number=Sing	_	_	_	_
14	combination	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	anti	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	Tat	_	NOUN	_	Number=Sing	_	_	_	_
19	single	_	ADJ	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	chain	_	NOUN	_	Number=Sing	_	_	_	_
22	intrabodies	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	antagonists	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	Tat	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	early	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	critical	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	viral	_	ADJ	_	Degree=Pos	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	replication	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	transactivates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	HIV	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	long	_	ADJ	_	Degree=Pos	_	_	_	_
33	terminal	_	NOUN	_	Number=Sing	_	_	_	_
34	repeat	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	LTR	_	PROPN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	via	_	ADP	_	_	_	_	_	_
39	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
40	binding	_	NOUN	_	Number=Sing	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
44	response	_	NOUN	_	Number=Sing	_	_	_	_
45	element	_	NOUN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	TAR	_	NOUN	_	Number=Sing	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	along	_	ADP	_	_	_	_	_	_
52	with	_	ADP	_	_	_	_	_	_
53	other	_	ADJ	_	Degree=Pos	_	_	_	_
54	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
55	factors	_	NOUN	_	Number=Plur	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
58	viral	_	ADJ	_	Degree=Pos	_	_	_	_
59	transcription	_	NOUN	_	Number=Sing	_	_	_	_
60	initiation	_	NOUN	_	Number=Sing	_	_	_	_
61	and	_	CCONJ	_	_	_	_	_	_
62	elongation	_	NOUN	_	Number=Sing	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	Tat	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	superactivates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	HIV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	TAR	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	independent	_	ADJ	_	Degree=Pos	_	_	_	_
14	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	including	_	VERB	_	VerbForm=Ger	_	_	_	_
17	tumor	_	NOUN	_	Number=Sing	_	_	_	_
18	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	protein	_	VERB	_	Number=Sing	_	_	_	_
25	kinase	_	NOUN	_	Number=Sing	_	_	_	_
26	C	_	PROPN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	PKC	_	PROPN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappa	_	NOUN	_	Number=Sing	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	Tat	_	PROPN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	NF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	kappa	_	PROPN	_	Number=Sing	_	_	_	_
47	B	_	PROPN	_	Number=Sing	_	_	_	_
48	cooperatively	_	ADV	_	_	_	_	_	_
49	down	_	ADV	_	_	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
52	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
53	Tat	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
56	LTR	_	PROPN	_	Number=Sing	_	_	_	_
57	superactivation	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	pharmacologic	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
10	strategy	_	NOUN	_	Number=Sing	_	_	_	_
11	using	_	VERB	_	VerbForm=Ger	_	_	_	_
12	two	_	NUM	_	NumType=Card	_	_	_	_
13	PKC	_	PROPN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	pentoxifylline	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	PTX	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	Go	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	6976	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	stably	_	ADV	_	_	_	_	_	_
34	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	anti-Tat	_	ADJ	_	Degree=Pos	_	_	_	_
36	single	_	ADJ	_	Degree=Pos	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	chain	_	NOUN	_	Number=Sing	_	_	_	_
39	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
40	antibody	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	sFv	_	NUM	_	Number=Sing	_	_	_	_
43	intrabody	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
46	employed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
47	to	_	PART	_	_	_	_	_	_
48	obtain	_	VERB	_	VerbForm=Inf	_	_	_	_
49	cooperative	_	ADJ	_	Degree=Pos	_	_	_	_
50	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	both	_	CCONJ	_	_	_	_	_	_
53	HIV	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	1	_	NUM	_	NumType=Card	_	_	_	_
56	LTR	_	NOUN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
59	gene	_	NOUN	_	Number=Sing	_	_	_	_
60	expression	_	NOUN	_	Number=Sing	_	_	_	_
61	and	_	CCONJ	_	_	_	_	_	_
62	HIV	_	NOUN	_	Number=Sing	_	_	_	_
63	-	_	PUNCT	_	_	_	_	_	_
64	1	_	NUM	_	NumType=Card	_	_	_	_
65	replication	_	NOUN	_	Number=Sing	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	PTX	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	Go	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	6976	_	NUM	_	NumType=Card	_	_	_	_
10	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	cooperative	_	ADJ	_	Degree=Pos	_	_	_	_
13	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	LTR	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	replication	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	use	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	anti-Tat	_	ADJ	_	Degree=Pos	_	_	_	_
9	sFv	_	NOUN	_	Number=Sing	_	_	_	_
10	intrabodies	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	two	_	NUM	_	NumType=Card	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
19	retained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	virus	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	latent	_	ADJ	_	Degree=Pos	_	_	_	_
25	state	_	NOUN	_	Number=Sing	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	as	_	ADV	_	_	_	_	_	_
28	long	_	ADV	_	Degree=Pos	_	_	_	_
29	as	_	ADP	_	_	_	_	_	_
30	45	_	NUM	_	NumType=Card	_	_	_	_
31	days	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	treatment	_	NOUN	_	Number=Sing	_	_	_	_
4	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	more	_	ADV	_	_	_	_	_	_
7	durable	_	ADJ	_	Degree=Pos	_	_	_	_
8	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	replication	_	NOUN	_	Number=Sing	_	_	_	_
14	than	_	SCONJ	_	_	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
24	alone	_	ADV	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	anti	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	Tat	_	NOUN	_	Number=Sing	_	_	_	_
30	sFv	_	NOUN	_	Number=Sing	_	_	_	_
31	intrabodies	_	NOUN	_	Number=Plur	_	_	_	_
32	alone	_	ADJ	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	future	_	ADJ	_	Degree=Pos	_	_	_	_
9	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	therapy	_	NOUN	_	Number=Sing	_	_	_	_
12	trials	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	pharmacologic	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
19	strategy	_	NOUN	_	Number=Sing	_	_	_	_
20	like	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	one	_	NOUN	_	Number=Sing	_	_	_	_
23	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	here	_	ADV	_	PronType=Dem	_	_	_	_
25	may	_	AUX	_	VerbForm=Fin	_	_	_	_
26	improve	_	VERB	_	VerbForm=Inf	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	survival	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	prolong	_	VERB	_	VerbForm=Inf	_	_	_	_
34	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
35	benefit	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011364	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	N-	_	PUNCT	_	_	_	_	_	_
2	acetyl	_	ADJ	_	Number=Sing	_	_	_	_
3	-L	_	PUNCT	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
6	inhibits	_	VERB	_	Number=Plur	_	_	_	_
7	primary	_	ADJ	_	Degree=Pos	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	responses	_	NOUN	_	Number=Plur	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	level	_	NOUN	_	Number=Sing	_	_	_	_
17	:	_	PUNCT	_	_	_	_	_	_
18	association	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	N-acetyl-L	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	cysteine	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	NAC	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
10	molecule	_	NOUN	_	Number=Sing	_	_	_	_
11	endowed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	immunomodulatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	properties	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NAC	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	phase	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	T	_	PROPN	_	NumType=Card	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	responses	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	action	_	NOUN	_	Number=Sing	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	DC	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	adherent	_	ADJ	_	Number=Sing	_	_	_	_
30	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
31	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	4	_	NUM	_	NumType=Card	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
40	CSF	_	PROPN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	first	_	ADV	_	_	_	_	_	_
3	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	NAC	_	PROPN	_	Number=Sing	_	_	_	_
6	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	constitutive	_	NOUN	_	Number=Sing	_	_	_	_
9	as	_	ADV	_	_	_	_	_	_
10	well	_	ADV	_	Degree=Pos	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	LPS	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	parallel	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	NAC	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	down	_	ADV	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	DC	_	PROPN	_	Number=Sing	_	_	_	_
17	as	_	ADV	_	_	_	_	_	_
18	well	_	ADV	_	Degree=Pos	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	surface	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	HLA	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	DR	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	CD86	_	PROPN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	B7	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	CD40	_	PROPN	_	Number=Sing	_	_	_	_
37	molecules	_	NOUN	_	Number=Plur	_	_	_	_
38	both	_	CCONJ	_	_	_	_	_	_
39	at	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	basal	_	ADJ	_	Degree=Pos	_	_	_	_
42	state	_	NOUN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	upon	_	ADP	_	_	_	_	_	_
45	LPS	_	NOUN	_	Number=Sing	_	_	_	_
46	activation	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	NAC	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	DC	_	PROPN	_	Number=Sing	_	_	_	_
5	responses	_	NOUN	_	Number=Plur	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	CD40	_	PROPN	_	Number=Sing	_	_	_	_
9	engagement	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NAC	_	PROPN	_	Number=Sing	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	due	_	ADP	_	_	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	nonspecific	_	ADJ	_	Degree=Pos	_	_	_	_
11	toxicity	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	neither	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	viability	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	DC	_	PROPN	_	Number=Sing	_	_	_	_
18	nor	_	CCONJ	_	_	_	_	_	_
19	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	mannose	_	ADJ	_	Degree=Pos	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
24	endocytosis	_	NOUN	_	Number=Sing	_	_	_	_
25	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	modified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	NAC	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	addition	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NAC	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	MLR	_	NOUN	_	Number=Sing	_	_	_	_
12	between	_	ADP	_	_	_	_	_	_
13	naive	_	ADJ	_	Degree=Pos	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	allogeneic	_	PROPN	_	Degree=Pos	_	_	_	_
18	DC	_	PROPN	_	Number=Sing	_	_	_	_
19	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	profound	_	ADJ	_	Degree=Pos	_	_	_	_
23	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	alloreactive	_	ADJ	_	Degree=Pos	_	_	_	_
26	responses	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	could	_	AUX	_	VerbForm=Fin	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	attributed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	defect	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	DC	_	PROPN	_	Number=Sing	_	_	_	_
37	as	_	ADP	_	_	_	_	_	_
38	APC	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	independent	_	ADJ	_	Degree=Pos	_	_	_	_
41	T	_	NOUN	_	Number=Sing	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	responses	_	NOUN	_	Number=Plur	_	_	_	_
44	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
45	not	_	PART	_	_	_	_	_	_
46	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
47	by	_	ADP	_	_	_	_	_	_
48	NAC	_	PROPN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Altogether	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	NAC	_	PROPN	_	Number=Sing	_	_	_	_
8	might	_	AUX	_	VerbForm=Fin	_	_	_	_
9	impair	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	generation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	primary	_	ADJ	_	Degree=Pos	_	_	_	_
14	immune	_	ADJ	_	Number=Sing	_	_	_	_
15	responses	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	humans	_	NOUN	_	Number=Plur	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
21	action	_	NOUN	_	Number=Sing	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	DC.	_	PROPN	_	Number=Sing	_	_	_	_
24	Document	_	NOUN	_	Number=Sing	_	_	_	_
25	0030011365	_	NUM	_	NumType=Card	_	_	_	_
26	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_

1	1	_	NUM	_	NumType=Card	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	Jun	_	PROPN	_	Number=Sing	_	_	_	_
6	N	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	terminal	_	NOUN	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	involved	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	PROPN	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	6	_	NUM	_	NumType=Card	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	possible	_	ADJ	_	Degree=Pos	_	_	_	_
9	involvement	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	mitogen	_	ADJ	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	kinase	_	NOUN	_	Number=Sing	_	_	_	_
17	family	_	NOUN	_	Number=Sing	_	_	_	_
18	members	_	NOUN	_	Number=Plur	_	_	_	_
19	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	kinase	_	NOUN	_	Number=Sing	_	_	_	_
23	1/2	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	ERK1	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
31	N	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
34	kinase	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	JNK	_	PROPN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	in	_	SCONJ	_	_	_	_	_	_
39	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	6	_	NUM	_	NumType=Card	_	_	_	_
43	gene	_	NOUN	_	Number=Sing	_	_	_	_
44	expression	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	human	_	ADJ	_	Degree=Pos	_	_	_	_
47	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	particular	_	ADJ	_	Degree=Pos	_	_	_	_
51	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
52	role	_	NOUN	_	Number=Sing	_	_	_	_
53	in	_	SCONJ	_	_	_	_	_	_
54	enhancing	_	VERB	_	VerbForm=Ger	_	_	_	_
55	NF	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	kappa	_	NOUN	_	Number=Sing	_	_	_	_
58	B	_	NOUN	_	Number=Sing	_	_	_	_
59	activity	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Freshly	_	ADV	_	_	_	_	_	_
2	isolated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
9	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
10	okadaic	_	NOUN	_	Number=Sing	_	_	_	_
11	acid	_	NOUN	_	Number=Sing	_	_	_	_
12	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	high	_	ADJ	_	Degree=Pos	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	6	_	NUM	_	NumType=Card	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	coincided	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	as	_	ADV	_	_	_	_	_	_
33	well	_	ADV	_	Degree=Pos	_	_	_	_
34	as	_	ADP	_	_	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	activation	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	ERK1	_	PROPN	_	Number=Sing	_	_	_	_
42	/	_	PUNCT	_	_	_	_	_	_
43	2	_	NUM	_	NumType=Card	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	JNK	_	PROPN	_	Number=Sing	_	_	_	_
46	proteins	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ERK	_	PROPN	_	Number=Sing	_	_	_	_
3	pathway	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
7	PD98059	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	6	_	NUM	_	NumType=Card	_	_	_	_
12	secretion	_	NOUN	_	Number=Sing	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
5	mutants	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	either	_	CCONJ	_	_	_	_	_	_
8	Raf	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	JNK1	_	PROPN	_	Number=Sing	_	_	_	_
13	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	both	_	DET	_	_	_	_	_	_
16	pathways	_	NOUN	_	Number=Plur	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	involved	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	kappa	_	PROPN	_	Number=Sing	_	_	_	_
21	B	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	6	_	NUM	_	NumType=Card	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	PD98059	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Raf1	_	PROPN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	MEK1	_	PROPN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	ERK1	_	PROPN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	pathway	_	NOUN	_	Number=Sing	_	_	_	_
17	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	PROPN	_	Number=Sing	_	_	_	_
27	B	_	PROPN	_	Number=Sing	_	_	_	_
28	but	_	CCONJ	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	rather	_	ADV	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	acted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	at	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	level	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
38	activity	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappa	_	PROPN	_	Number=Sing	_	_	_	_
43	B.	_	PROPN	_	Number=Sing	_	_	_	_
44	Interestingly	_	ADV	_	_	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
47	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
48	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
49	that	_	SCONJ	_	_	_	_	_	_
50	NF	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	kappa	_	PROPN	_	Number=Sing	_	_	_	_
53	B	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
56	gene	_	NOUN	_	Number=Sing	_	_	_	_
57	transcription	_	NOUN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	both	_	CCONJ	_	_	_	_	_	_
60	in	_	ADP	_	_	_	_	_	_
61	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
62	context	_	NOUN	_	Number=Sing	_	_	_	_
63	of	_	ADP	_	_	_	_	_	_
64	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
65	IL	_	PROPN	_	Number=Sing	_	_	_	_
66	-	_	PUNCT	_	_	_	_	_	_
67	6	_	NUM	_	NumType=Card	_	_	_	_
68	promoter	_	NOUN	_	Number=Sing	_	_	_	_
69	as	_	ADV	_	_	_	_	_	_
70	well	_	ADV	_	Degree=Pos	_	_	_	_
71	as	_	ADP	_	_	_	_	_	_
72	on	_	ADP	_	_	_	_	_	_
73	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
74	own	_	ADJ	_	Degree=Pos	_	_	_	_
75	,	_	PUNCT	_	_	_	_	_	_
76	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
77	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
78	on	_	ADP	_	_	_	_	_	_
79	both	_	DET	_	_	_	_	_	_
80	serine	_	NOUN	_	Number=Sing	_	_	_	_
81	kinase	_	NOUN	_	Number=Sing	_	_	_	_
82	activity	_	NOUN	_	Number=Sing	_	_	_	_
83	and	_	CCONJ	_	_	_	_	_	_
84	interaction	_	NOUN	_	Number=Sing	_	_	_	_
85	with	_	ADP	_	_	_	_	_	_
86	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
87	protein	_	NOUN	_	Number=Sing	_	_	_	_
88	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
5	acid	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	at	_	ADV	_	_	_	_	_	_
15	least	_	ADV	_	Degree=Sup	_	_	_	_
16	partly	_	ADV	_	_	_	_	_	_
17	mediated	_	VERB	_	Degree=Pos	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	ERK1	_	PROPN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	JNK	_	PROPN	_	Number=Sing	_	_	_	_
25	pathway	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
35	capacity	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	JNK	_	PROPN	_	Number=Sing	_	_	_	_
7	pathway	_	NOUN	_	Number=Sing	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	PROPN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	VERB	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011377	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	C	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	interleukin	_	ADJ	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	secretion	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	express	_	VERB	_	Degree=Pos	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1beta	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1beta	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	when	_	ADV	_	PronType=Int	_	_	_	_
14	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	matrix	_	NOUN	_	Number=Sing	_	_	_	_
19	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	FN	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	PROPN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	C	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	PKC	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	considered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	process	_	NOUN	_	Number=Sing	_	_	_	_
14	;	_	PUNCT	_	_	_	_	_	_
15	however	_	ADV	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	metabolic	_	ADJ	_	Degree=Pos	_	_	_	_
19	steps	_	NOUN	_	Number=Plur	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	PKC	_	PROPN	_	Number=Sing	_	_	_	_
23	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	upon	_	ADP	_	_	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	FN	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1beta	_	NOUN	_	Number=Sing	_	_	_	_
34	response	_	NOUN	_	Number=Sing	_	_	_	_
35	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	performed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	PKC	_	NOUN	_	Number=Sing	_	_	_	_
12	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	Calphostin	_	PROPN	_	Number=Sing	_	_	_	_
15	C	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	Staurosporine	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	FN	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1beta	_	PROPN	_	Number=Sing	_	_	_	_
27	response	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
3	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	secretion	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1beta	_	PROPN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	into	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	media	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
16	blood	_	NOUN	_	Number=Sing	_	_	_	_
17	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	FN	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Immunoprecipitation	_	PROPN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	under	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	circumstances	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	Calphostin	_	PROPN	_	Number=Sing	_	_	_	_
10	C	_	PROPN	_	Number=Sing	_	_	_	_
11	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1beta	_	PROPN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	whereas	_	SCONJ	_	_	_	_	_	_
21	Staurosporine	_	PROPN	_	Number=Sing	_	_	_	_
22	allowed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	production	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
29	secretion	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	differences	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	turned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	U937	_	NOUN	_	Number=Sing	_	_	_	_
15	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	U937	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	full	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	length	_	NOUN	_	Number=Sing	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1beta	_	PROPN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	connected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
18	reporter	_	NOUN	_	Number=Sing	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	submitted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	assays	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
27	blotting	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	DNA	_	PROPN	_	Number=Sing	_	_	_	_
31	electrophoresis	_	NOUN	_	Number=Sing	_	_	_	_
32	mobility	_	NOUN	_	Number=Sing	_	_	_	_
33	gel	_	NOUN	_	Number=Sing	_	_	_	_
34	shift	_	NOUN	_	Number=Sing	_	_	_	_
35	assays	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Calphostin	_	PROPN	_	Number=Sing	_	_	_	_
6	C	_	PROPN	_	Number=Sing	_	_	_	_
7	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	translocation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	activator	_	NOUN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	considered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	FN	_	PROPN	_	Number=Sing	_	_	_	_
30	induction	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1beta	_	PROPN	_	Number=Sing	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	transcription	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	transcription	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	IL	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1beta	_	PROPN	_	Number=Sing	_	_	_	_
47	gene	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	Staurosporine	_	PROPN	_	Number=Sing	_	_	_	_
5	alone	_	ADV	_	_	_	_	_	_
6	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	AP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	translocation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Overall	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	Calphostin	_	PROPN	_	Number=Sing	_	_	_	_
8	C	_	PROPN	_	Number=Sing	_	_	_	_
9	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1beta	_	PROPN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	thereby	_	ADV	_	_	_	_	_	_
19	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	high	_	ADJ	_	Degree=Pos	_	_	_	_
5	specificity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	compound	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	PKC	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	PKC	_	PROPN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	FN	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1beta	_	PROPN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	production	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	Staurosporine	_	NOUN	_	Number=Sing	_	_	_	_
5	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	secretion	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1beta	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
13	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011379	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Dependence	_	NOUN	_	Number=Sing	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
5	response	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	program	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	line	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	UT	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	7	_	NUM	_	NumType=Card	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Erythroid	_	ADJ	_	Number=Sing	_	_	_	_
2	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
3	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	number	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	most	_	ADJ	_	Degree=Sup	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Int	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	including	_	VERB	_	VerbForm=Ger	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	globin	_	ADJ	_	Degree=Pos	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	Epo	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	R	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	at	_	ADV	_	_	_	_	_	_
37	least	_	ADV	_	Degree=Sup	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	part	_	ADJ	_	Degree=Pos	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	by	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	transcription	_	NOUN	_	Number=Sing	_	_	_	_
45	factor	_	NOUN	_	Number=Sing	_	_	_	_
46	GATA	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	1	_	NUM	_	NumType=Card	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	relationship	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	if	_	SCONJ	_	_	_	_	_	_
9	any	_	DET	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	between	_	ADP	_	_	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	GATA	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	Epo	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
26	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	GATA	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	Epo	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	R	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	globin	_	ADJ	_	Degree=Pos	_	_	_	_
39	genes	_	NOUN	_	Number=Plur	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	Epo	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
45	human	_	ADJ	_	Degree=Pos	_	_	_	_
46	cell	_	NOUN	_	Number=Sing	_	_	_	_
47	line	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	UT	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	7	_	NUM	_	NumType=Card	_	_	_	_
52	Epo	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
7	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	parental	_	ADJ	_	Degree=Pos	_	_	_	_
11	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
14	colony	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	GM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	CSF	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	line	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	UT	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	7	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	predominantly	_	ADV	_	_	_	_	_	_
36	megakaryoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
37	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	unable	_	ADJ	_	Degree=Pos	_	_	_	_
41	to	_	PART	_	_	_	_	_	_
42	proliferate	_	VERB	_	VerbForm=Inf	_	_	_	_
43	continuously	_	ADV	_	_	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	presence	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	Epo	_	PROPN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	UT	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	7	_	NUM	_	NumType=Card	_	_	_	_
4	Epo	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	UT	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	7	_	NUM	_	NumType=Card	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	similar	_	ADJ	_	Degree=Pos	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	GATA	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Epo	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	R	_	PROPN	_	Number=Sing	_	_	_	_
12	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
13	while	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	number	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Epo	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	binding	_	VERB	_	Number=Sing	_	_	_	_
20	sites	_	NOUN	_	Number=Plur	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	UT	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	7	_	NUM	_	NumType=Card	_	_	_	_
25	Epo	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	one	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	sixth	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	number	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	UT	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	7	_	NUM	_	NumType=Card	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	2400	_	NUM	_	NumType=Card	_	_	_	_
40	+/-	_	SYM	_	_	_	_	_	_
41	3	_	NUM	_	NumType=Card	_	_	_	_
42	vs.	_	ADP	_	_	_	_	_	_
43	13,800	_	NUM	_	NumType=Card	_	_	_	_
44	+/-	_	SYM	_	_	_	_	_	_
45	300	_	NUM	_	NumType=Card	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	difference	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	number	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	sites	_	NOUN	_	Number=Plur	_	_	_	_
9	could	_	AUX	_	VerbForm=Fin	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	due	_	ADP	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	differences	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	surface	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	UT	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	7	_	NUM	_	NumType=Card	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	20	_	NUM	_	NumType=Card	_	_	_	_
24	%	_	SYM	_	Number=Sing	_	_	_	_
25	smaller	_	ADJ	_	Degree=Cmp	_	_	_	_
26	than	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	parental	_	ADJ	_	Degree=Pos	_	_	_	_
29	UT	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	7	_	NUM	_	NumType=Card	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	receptor	_	NOUN	_	Number=Sing	_	_	_	_
37	turnover	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	UT	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	7	_	NUM	_	NumType=Card	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	gamma	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	globin	_	NOUN	_	Number=Sing	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	globin	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	comparison	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	UT	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	7	_	NUM	_	NumType=Card	_	_	_	_
7	Epo	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	globin	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	gamma	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	globin	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	5	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	fold	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	beta-globin	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	barely	_	ADV	_	_	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	clearly	_	ADV	_	_	_	_	_	_
32	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Globin	_	ADJ	_	Degree=Pos	_	_	_	_
2	chains	_	NOUN	_	Number=Plur	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	clearly	_	ADV	_	_	_	_	_	_
12	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	affinity	_	NOUN	_	Number=Sing	_	_	_	_
15	chromatography	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	UT	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	7	_	NUM	_	NumType=Card	_	_	_	_
20	Epo	_	PROPN	_	Number=Sing	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	UT	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	7	_	NUM	_	NumType=Card	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	frequency	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	beta	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	globin	_	ADJ	_	Degree=Pos	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	populations	_	NOUN	_	Number=Plur	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	beta	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	gamma-specific	_	ADJ	_	Degree=Pos	_	_	_	_
29	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	number	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	gamma	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	positive	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	fluorescence	_	NOUN	_	Number=Sing	_	_	_	_
11	intensity	_	NOUN	_	Number=Sing	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	UT	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	7	_	NUM	_	NumType=Card	_	_	_	_
18	Epo	_	PROPN	_	Number=Sing	_	_	_	_
19	than	_	ADP	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	UT	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	7	_	NUM	_	NumType=Card	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	0	_	NUM	_	NumType=Card	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	17	_	NUM	_	NumType=Card	_	_	_	_
29	%	_	SYM	_	Number=Sing	_	_	_	_
30	barely	_	ADV	_	_	_	_	_	_
31	positive	_	ADJ	_	Degree=Pos	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	23	_	NUM	_	NumType=Card	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	40	_	NUM	_	NumType=Card	_	_	_	_
37	%	_	SYM	_	Number=Sing	_	_	_	_
38	clearly	_	ADV	_	_	_	_	_	_
39	positive	_	ADJ	_	Degree=Pos	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	respectively	_	ADV	_	_	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
46	that	_	SCONJ	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	increase	_	NOUN	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	globin	_	ADJ	_	Degree=Pos	_	_	_	_
51	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
52	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	UT	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	7	_	NUM	_	NumType=Card	_	_	_	_
57	Epo	_	NOUN	_	Number=Sing	_	_	_	_
58	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
59	due	_	ADP	_	_	_	_	_	_
60	to	_	ADP	_	_	_	_	_	_
61	both	_	CCONJ	_	_	_	_	_	_
62	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
63	increase	_	NOUN	_	Number=Sing	_	_	_	_
64	of	_	ADP	_	_	_	_	_	_
65	gene	_	NOUN	_	Number=Sing	_	_	_	_
66	expression	_	NOUN	_	Number=Sing	_	_	_	_
67	per	_	ADP	_	_	_	_	_	_
68	cell	_	NOUN	_	Number=Sing	_	_	_	_
69	and	_	CCONJ	_	_	_	_	_	_
70	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
71	increase	_	NOUN	_	Number=Sing	_	_	_	_
72	in	_	ADP	_	_	_	_	_	_
73	numbers	_	NOUN	_	Number=Plur	_	_	_	_
74	of	_	ADP	_	_	_	_	_	_
75	cells	_	NOUN	_	Number=Plur	_	_	_	_
76	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
77	gamma	_	NOUN	_	Number=Sing	_	_	_	_
78	-	_	PUNCT	_	_	_	_	_	_
79	globin	_	NOUN	_	Number=Sing	_	_	_	_
80	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	GATA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	Epo	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	R	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	globin	_	PROPN	_	Degree=Pos	_	_	_	_
13	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
14	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	24	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	hour	_	NOUN	_	Number=Sing	_	_	_	_
23	incubation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	either	_	CCONJ	_	_	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	line	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	Epo	_	PROPN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	GM	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	CSF	_	NOUN	_	Number=Sing	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	3	_	NUM	_	NumType=Card	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	3	_	NUM	_	NumType=Card	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	400	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	0030011381	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Barr	_	PROPN	_	Number=Sing	_	_	_	_
4	viral	_	ADJ	_	Degree=Pos	_	_	_	_
5	latency	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	disrupted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	early	_	ADJ	_	Degree=Pos	_	_	_	_
13	BRLF1	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Barr	_	PROPN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EBV	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	causative	_	ADJ	_	Degree=Pos	_	_	_	_
11	agent	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	infectious	_	ADJ	_	Degree=Pos	_	_	_	_
14	mononucleosis	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
20	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	malignancies	_	NOUN	_	Number=Plur	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	nasopharyngeal	_	ADJ	_	Degree=Pos	_	_	_	_
27	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	as	_	ADV	_	_	_	_	_	_
30	well	_	ADV	_	Degree=Pos	_	_	_	_
31	as	_	ADP	_	_	_	_	_	_
32	B	_	ADJ	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	malignancies	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Understanding	_	NOUN	_	VerbForm=Ger	_	_	_	_
2	how	_	ADV	_	PronType=Int	_	_	_	_
3	viral	_	ADJ	_	Degree=Pos	_	_	_	_
4	latency	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	disrupted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	central	_	ADJ	_	Degree=Pos	_	_	_	_
10	issue	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
13	biology	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	major	_	ADJ	_	Degree=Pos	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	EBV	_	PROPN	_	Number=Sing	_	_	_	_
10	replication	_	NOUN	_	Number=Sing	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	host	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	viral	_	ADJ	_	Degree=Pos	_	_	_	_
18	reactivation	_	NOUN	_	Number=Sing	_	_	_	_
19	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	EBV	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	nasopharyngeal	_	ADJ	_	Degree=Pos	_	_	_	_
25	carcinomas	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	single	_	ADJ	_	Degree=Pos	_	_	_	_
9	viral	_	ADJ	_	Degree=Pos	_	_	_	_
10	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	early	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	BZLF1	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	switch	_	NOUN	_	Number=Sing	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	latent	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
27	infection	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	B	_	ADJ	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Cellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	BZLF1	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	therefore	_	ADV	_	_	_	_	_	_
8	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	play	_	VERB	_	VerbForm=Inf	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	key	_	ADJ	_	Degree=Pos	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	SCONJ	_	_	_	_	_	_
15	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	stringency	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	viral	_	ADJ	_	Degree=Pos	_	_	_	_
20	latency	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	unexpectedly	_	ADV	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	another	_	DET	_	_	_	_	_	_
11	viral	_	ADJ	_	Degree=Pos	_	_	_	_
12	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	early	_	ADJ	_	Degree=Pos	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	BRLF1	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	can	_	AUX	_	VerbForm=Fin	_	_	_	_
20	disrupt	_	VERB	_	VerbForm=Inf	_	_	_	_
21	viral	_	ADJ	_	Degree=Pos	_	_	_	_
22	latency	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	specific	_	ADJ	_	Degree=Pos	_	_	_	_
29	fashion	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	disruption	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	EBV	_	PROPN	_	Number=Sing	_	_	_	_
10	latency	_	NOUN	_	Number=Sing	_	_	_	_
11	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	type	_	NOUN	_	Number=Sing	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011382	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	c	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	jun	_	NOUN	_	Number=Sing	_	_	_	_
6	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	hydroxyurea	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	K562	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	during	_	ADP	_	_	_	_	_	_
15	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	[	_	PUNCT	_	_	_	_	_	_
18	published	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	erratum	_	NOUN	_	Number=Sing	_	_	_	_
20	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	Biochim	_	PROPN	_	Number=Sing	_	_	_	_
23	Biophys	_	PROPN	_	Number=Sing	_	_	_	_
24	Acta	_	PROPN	_	Number=Sing	_	_	_	_
25	1995	_	NUM	_	NumType=Card	_	_	_	_
26	Dec	_	PROPN	_	Number=Sing	_	_	_	_
27	27;1264	_	NUM	_	NumType=Card	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	3):409	_	NUM	_	NumType=Card	_	_	_	_
30	]	_	PUNCT	_	_	_	_	_	_
31	Hydroxyurea	_	PROPN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	HU	_	PROPN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	antitumor	_	NOUN	_	Number=Sing	_	_	_	_
38	agent	_	NOUN	_	Number=Sing	_	_	_	_
39	which	_	PRON	_	PronType=Rel	_	_	_	_
40	also	_	ADV	_	_	_	_	_	_
41	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	hemoglobinization	_	NOUN	_	Number=Sing	_	_	_	_
43	during	_	ADP	_	_	_	_	_	_
44	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
45	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	HU	_	PROPN	_	Number=Sing	_	_	_	_
5	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	fetal	_	ADJ	_	Number=Sing	_	_	_	_
10	hemoglobin	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	sickle	_	ADJ	_	Degree=Pos	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	anemia	_	NOUN	_	Number=Sing	_	_	_	_
15	patients	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
4	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
5	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	action	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	effects	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	HU	_	PROPN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	c	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	jun	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	prior	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	onset	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
28	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	K562	_	NUM	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	HU	_	PROPN	_	Number=Sing	_	_	_	_
2	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	dose	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	c	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	jun	_	NOUN	_	Number=Sing	_	_	_	_
12	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	jun	_	NOUN	_	Number=Sing	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	elevated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	7.5	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	HU	_	PROPN	_	Number=Sing	_	_	_	_
17	within	_	ADP	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	h	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	followed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	gradual	_	ADJ	_	Degree=Pos	_	_	_	_
7	decline	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	basal	_	ADJ	_	Degree=Pos	_	_	_	_
11	level	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	24	_	NUM	_	NumType=Card	_	_	_	_
14	h	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	run	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	on	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	actinomycin	_	PROPN	_	Number=Sing	_	_	_	_
8	D	_	PROPN	_	Number=Sing	_	_	_	_
9	pulse	_	NOUN	_	Number=Sing	_	_	_	_
10	experiments	_	NOUN	_	Number=Plur	_	_	_	_
11	strongly	_	ADV	_	_	_	_	_	_
12	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	HU	_	PROPN	_	Number=Sing	_	_	_	_
15	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
17	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	SCONJ	_	_	_	_	_	_
20	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	rate	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
25	as	_	ADV	_	_	_	_	_	_
26	well	_	ADV	_	Degree=Pos	_	_	_	_
27	as	_	SCONJ	_	_	_	_	_	_
28	stabilizing	_	VERB	_	VerbForm=Ger	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	c	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	jun	_	NOUN	_	Number=Sing	_	_	_	_
33	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	level	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	jun	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	elevated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	5	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	fold	_	NOUN	_	VerbForm=Inf	_	_	_	_
17	within	_	ADP	_	_	_	_	_	_
18	4	_	NUM	_	NumType=Card	_	_	_	_
19	h	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	HU	_	PROPN	_	Number=Sing	_	_	_	_
22	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	HU	_	PROPN	_	Number=Sing	_	_	_	_
6	below	_	ADP	_	_	_	_	_	_
7	250	_	NUM	_	NumType=Card	_	_	_	_
8	microM	_	NOUN	_	Number=Sing	_	_	_	_
9	slightly	_	ADV	_	_	_	_	_	_
10	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	5X	_	NUM	_	NumType=Card	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1/CAT	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	strongly	_	ADV	_	_	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	HU	_	PROPN	_	Number=Sing	_	_	_	_
7	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	post	_	VERB	_	VerbForm=Inf	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	c	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	jun	_	NOUN	_	Number=Sing	_	_	_	_
19	during	_	ADP	_	_	_	_	_	_
20	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011392	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	CML	_	PROPN	_	Number=Sing	_	_	_	_
4	patients	_	NOUN	_	Number=Plur	_	_	_	_
5	lack	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	47	_	NUM	_	NumType=Card	_	_	_	_
8	kDa	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	having	_	VERB	_	VerbForm=Ger	_	_	_	_
11	affinity	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
15	sterol	_	NOUN	_	Number=Sing	_	_	_	_
16	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Deranged	_	ADJ	_	Degree=Pos	_	_	_	_
2	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	cholesterol	_	NOUN	_	Number=Sing	_	_	_	_
4	homeostasis	_	NOUN	_	Number=Sing	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	widely	_	ADV	_	_	_	_	_	_
8	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	initiation	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADV	_	_	_	_	_	_
13	well	_	ADV	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	progression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	various	_	ADJ	_	Degree=Pos	_	_	_	_
18	types	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	cancers	_	NOUN	_	Number=Plur	_	_	_	_
21	including	_	VERB	_	VerbForm=Ger	_	_	_	_
22	chronic	_	ADJ	_	Number=Sing	_	_	_	_
23	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
24	leukaemia	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	CML	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
5	sterol	_	NOUN	_	Number=Sing	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	SRE	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	various	_	ADJ	_	Degree=Pos	_	_	_	_
17	key	_	ADJ	_	Degree=Pos	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	present	_	ADJ	_	Degree=Pos	_	_	_	_
26	study	_	NOUN	_	Number=Sing	_	_	_	_
27	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	existence	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	unique	_	ADJ	_	Degree=Pos	_	_	_	_
33	47	_	NUM	_	NumType=Card	_	_	_	_
34	kDa	_	NOUN	_	Number=Sing	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	factor	_	NOUN	_	Number=Sing	_	_	_	_
37	having	_	VERB	_	VerbForm=Ger	_	_	_	_
38	affinity	_	NOUN	_	Number=Sing	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
41	SRE	_	NOUN	_	Number=Sing	_	_	_	_
42	sequence	_	NOUN	_	Number=Sing	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
45	from	_	ADP	_	_	_	_	_	_
46	normal	_	ADJ	_	Degree=Pos	_	_	_	_
47	subjects	_	NOUN	_	Number=Plur	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	as	_	ADV	_	_	_	_	_	_
50	well	_	ADV	_	Degree=Pos	_	_	_	_
51	as	_	ADP	_	_	_	_	_	_
52	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
53	absence	_	NOUN	_	Number=Sing	_	_	_	_
54	in	_	ADP	_	_	_	_	_	_
55	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
56	from	_	ADP	_	_	_	_	_	_
57	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
58	CML	_	NOUN	_	Number=Sing	_	_	_	_
59	patients	_	NOUN	_	Number=Plur	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	when	_	ADV	_	PronType=Int	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	CML	_	NOUN	_	Number=Sing	_	_	_	_
9	patients	_	NOUN	_	Number=Plur	_	_	_	_
10	achieved	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	complete	_	ADJ	_	Degree=Pos	_	_	_	_
12	haematological	_	ADJ	_	Degree=Pos	_	_	_	_
13	remission	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	CHR	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	through	_	ADP	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	interferon	_	NOUN	_	Number=Sing	_	_	_	_
21	therapy	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	inverse	_	ADJ	_	Degree=Pos	_	_	_	_
5	relationship	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	LDL	_	PROPN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	level	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	affinity	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	47	_	NUM	_	NumType=Card	_	_	_	_
26	kDa	_	NOUN	_	Number=Sing	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	SRE	_	NOUN	_	Number=Sing	_	_	_	_
32	sequence	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	upon	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	have	_	VERB	_	VerbForm=Inf	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	pathophysiology	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	chronic	_	ADJ	_	Number=Sing	_	_	_	_
18	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
19	leukaemia	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011394	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Positive	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulators	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	lineage	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	GATA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	zinc	_	NOUN	_	Number=Sing	_	_	_	_
3	finger	_	NOUN	_	Number=Sing	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	GATA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	major	_	ADJ	_	Degree=Pos	_	_	_	_
12	regulator	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	megakaryocyte	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	mast	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	lineages	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	GATA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	binds	_	NOUN	_	Number=Plur	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	WGATAR	_	VERB	_	VerbForm=Inf	_	_	_	_
7	consensus	_	NOUN	_	Number=Sing	_	_	_	_
8	motifs	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	regions	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	virtually	_	ADV	_	_	_	_	_	_
15	all	_	DET	_	_	_	_	_	_
16	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Analyses	_	NOUN	_	Number=Plur	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	cultured	_	VERB	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	free	_	ADJ	_	Degree=Pos	_	_	_	_
9	systems	_	NOUN	_	Number=Plur	_	_	_	_
10	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	provided	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	strong	_	ADJ	_	Degree=Pos	_	_	_	_
13	evidence	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	GATA	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	involved	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	control	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	globin	_	ADJ	_	Degree=Pos	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	during	_	ADP	_	_	_	_	_	_
27	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
28	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	GATA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
11	stem	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	requirement	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
20	development	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Efficient	_	ADJ	_	Degree=Pos	_	_	_	_
2	rescue	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	defect	_	NOUN	_	Number=Sing	_	_	_	_
6	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	intact	_	ADJ	_	Degree=Pos	_	_	_	_
9	GATA	_	NOUN	_	Number=Sing	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	distal	_	ADJ	_	Degree=Pos	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	control	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	GATA	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	GATA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	additional	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	maintained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	entirely	_	ADV	_	_	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	loop	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
22	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	transient	_	ADJ	_	Degree=Pos	_	_	_	_
26	heterokaryon	_	NOUN	_	Number=Sing	_	_	_	_
27	system	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	test	_	VERB	_	VerbForm=Inf	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	ability	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
34	factors	_	NOUN	_	Number=Plur	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	GATA	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	gene	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	nonerythroid	_	ADJ	_	Degree=Pos	_	_	_	_
44	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	proerythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	mature	_	ADJ	_	Degree=Pos	_	_	_	_
8	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	diffusible	_	ADJ	_	Degree=Pos	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TAG	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	capable	_	ADJ	_	Degree=Pos	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	GATA	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	decreases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	during	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
33	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Nuclei	_	NOUN	_	Number=Plur	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	GATA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1-	_	NUM	_	NumType=Card	_	_	_	_
6	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
7	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
8	stem	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	still	_	ADV	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	reprogrammed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	express	_	VERB	_	VerbForm=Inf	_	_	_	_
16	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	globin	_	ADJ	_	Degree=Pos	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
21	heterokaryons	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	de	_	PROPN	_	Number=Sing	_	_	_	_
26	novo	_	PROPN	_	Number=Sing	_	_	_	_
27	induction	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	GATA	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	not	_	PART	_	_	_	_	_	_
34	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	globin	_	ADJ	_	Degree=Pos	_	_	_	_
37	gene	_	NOUN	_	Number=Sing	_	_	_	_
38	activation	_	NOUN	_	Number=Sing	_	_	_	_
39	following	_	VERB	_	VerbForm=Ger	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	fusion	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011398	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Possible	_	ADJ	_	Degree=Pos	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	germline	_	NOUN	_	Number=Sing	_	_	_	_
12	C	_	PROPN	_	Number=Sing	_	_	_	_
13	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	Burkitt	_	NOUN	_	Number=Sing	_	_	_	_
19	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	line	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	broad	_	ADJ	_	Degree=Pos	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	regulation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	evident	_	ADJ	_	Degree=Pos	_	_	_	_
25	whether	_	SCONJ	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	PROPN	_	Number=Sing	_	_	_	_
29	B	_	PROPN	_	Number=Sing	_	_	_	_
30	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	as	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	messenger	_	NOUN	_	Number=Sing	_	_	_	_
34	system	_	NOUN	_	Number=Sing	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	germline	_	NOUN	_	Number=Sing	_	_	_	_
37	C	_	PROPN	_	Number=Sing	_	_	_	_
38	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	signaling	_	NOUN	_	Number=Sing	_	_	_	_
7	cascade	_	NOUN	_	Number=Sing	_	_	_	_
8	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	anti-CD40	_	NUM	_	Number=Sing	_	_	_	_
20	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
21	antibody	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	mAb	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	participates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	PROPN	_	Number=Sing	_	_	_	_
30	B	_	PROPN	_	Number=Sing	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
33	for	_	ADP	_	_	_	_	_	_
34	germline	_	NOUN	_	Number=Sing	_	_	_	_
35	C	_	PROPN	_	Number=Sing	_	_	_	_
36	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	human	_	ADJ	_	Degree=Pos	_	_	_	_
41	Burkitt	_	NOUN	_	Number=Sing	_	_	_	_
42	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
43	B	_	NOUN	_	Number=Sing	_	_	_	_
44	cell	_	NOUN	_	Number=Sing	_	_	_	_
45	line	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	DND39	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	4	_	NUM	_	NumType=Card	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	anti-CD40	_	PROPN	_	Number=Sing	_	_	_	_
7	mAb	_	NOUN	_	Number=Sing	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	phosphatidylinositol	_	PROPN	_	Number=Sing	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kinase	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	PI3	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kinase	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	translocation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	zeta	_	NOUN	_	Number=Sing	_	_	_	_
25	isoform	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	kinase	_	NOUN	_	Number=Sing	_	_	_	_
29	C	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	such	_	ADJ	_	Degree=Pos	_	_	_	_
3	events	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	abrogated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	treatment	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	LY294002	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	PI3	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	N-acetyl	_	PROPN	_	Number=Sing	_	_	_	_
5	-L	_	PUNCT	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	cysteine	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	NAC	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	potent	_	ADJ	_	Degree=Pos	_	_	_	_
14	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	4	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	anti-CD40	_	PROPN	_	Number=Sing	_	_	_	_
29	mAb	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
33	combination	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	NAC	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	effective	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	SCONJ	_	_	_	_	_	_
6	diminishing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	germline	_	NOUN	_	Number=Sing	_	_	_	_
8	C	_	PROPN	_	Number=Sing	_	_	_	_
9	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	potency	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	cultures	_	NOUN	_	Number=Plur	_	_	_	_
19	costimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	4	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	anti-CD40	_	PROPN	_	NumType=Card	_	_	_	_
26	mAb	_	NOUN	_	Number=Sing	_	_	_	_
27	than	_	ADP	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
30	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	4	_	NUM	_	NumType=Card	_	_	_	_
35	alone	_	ADJ	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	ligation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	CD40	_	PROPN	_	Number=Sing	_	_	_	_
12	induce	_	VERB	_	Number=Sing	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	via	_	ADP	_	_	_	_	_	_
19	at	_	ADV	_	_	_	_	_	_
20	least	_	ADV	_	Degree=Sup	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
23	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	PI3	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kinase	_	NOUN	_	Number=Sing	_	_	_	_
29	pathway	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	that	_	SCONJ	_	_	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	NAC	_	PROPN	_	Number=Sing	_	_	_	_
40	may	_	AUX	_	VerbForm=Fin	_	_	_	_
41	play	_	VERB	_	VerbForm=Inf	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	role	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	SCONJ	_	_	_	_	_	_
45	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
46	germline	_	NOUN	_	Number=Sing	_	_	_	_
47	C	_	PROPN	_	Number=Sing	_	_	_	_
48	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
49	transcription	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011402	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cross	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	linking	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Fc	_	PROPN	_	Number=Sing	_	_	_	_
6	gamma	_	NOUN	_	Number=Sing	_	_	_	_
7	receptors	_	NOUN	_	Number=Plur	_	_	_	_
8	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	long	_	ADJ	_	Degree=Pos	_	_	_	_
13	terminal	_	NOUN	_	Number=Sing	_	_	_	_
14	repeat	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Elevation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
7	immune	_	ADJ	_	Number=Sing	_	_	_	_
8	complexes	_	NOUN	_	Number=Plur	_	_	_	_
9	frequently	_	ADV	_	_	_	_	_	_
10	accompanies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	infection	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	prognostic	_	ADJ	_	Degree=Pos	_	_	_	_
19	indicator	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
22	progression	_	NOUN	_	Number=Sing	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	asymptomatic	_	ADJ	_	Degree=Pos	_	_	_	_
25	infection	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	cross	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	linking	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Fc	_	PROPN	_	Number=Sing	_	_	_	_
10	gamma	_	PROPN	_	Number=Sing	_	_	_	_
11	RI	_	PROPN	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	Fc	_	PROPN	_	Number=Sing	_	_	_	_
14	gamma	_	PROPN	_	Number=Sing	_	_	_	_
15	RII	_	PROPN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	adherent	_	ADJ	_	VerbForm=Ger	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	IgG	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	anti-Fc	_	ADJ	_	Degree=Pos	_	_	_	_
24	gamma	_	NOUN	_	Number=Sing	_	_	_	_
25	R	_	NOUN	_	Number=Sing	_	_	_	_
26	mAb	_	NOUN	_	Number=Sing	_	_	_	_
27	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	HIV	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	human	_	ADJ	_	Degree=Pos	_	_	_	_
36	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	line	_	NOUN	_	Number=Sing	_	_	_	_
39	BF24	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	HIV	_	NOUN	_	Number=Sing	_	_	_	_
43	RNA	_	PROPN	_	Number=Sing	_	_	_	_
44	expression	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
47	from	_	ADP	_	_	_	_	_	_
48	HIV	_	NOUN	_	Number=Sing	_	_	_	_
49	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	patients	_	NOUN	_	Number=Plur	_	_	_	_
51	as	_	SCONJ	_	_	_	_	_	_
52	assayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
53	by	_	ADP	_	_	_	_	_	_
54	reverse	_	NOUN	_	Number=Sing	_	_	_	_
55	transcription	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	PCR	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	THP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	Fc	_	PROPN	_	Number=Sing	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	R	_	NOUN	_	Number=Sing	_	_	_	_
10	cross	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	linking	_	VERB	_	Number=Sing	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	region	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	long	_	ADJ	_	Degree=Pos	_	_	_	_
31	terminal	_	NOUN	_	Number=Sing	_	_	_	_
32	repeat	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	LTR	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	HIV	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	to	_	PART	_	_	_	_	_	_
42	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
43	HIV	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	transcription	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Anti-TNF	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	antibody	_	NOUN	_	Number=Sing	_	_	_	_
5	but	_	CCONJ	_	_	_	_	_	_
6	not	_	ADV	_	_	_	_	_	_
7	anti-IL	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	beta	_	NOUN	_	Number=Sing	_	_	_	_
11	antibody	_	NOUN	_	Number=Sing	_	_	_	_
12	strongly	_	ADV	_	_	_	_	_	_
13	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	HIV	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1-LTR	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	induction	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	Fc	_	PROPN	_	Number=Sing	_	_	_	_
34	gamma	_	NOUN	_	Number=Sing	_	_	_	_
35	R	_	NOUN	_	Number=Sing	_	_	_	_
36	cross	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	linking	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Fc	_	PROPN	_	Number=Sing	_	_	_	_
6	gamma	_	NOUN	_	Number=Sing	_	_	_	_
7	R	_	NOUN	_	Number=Sing	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha-dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	suggest	_	VERB	_	VerbForm=Inf	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	immune	_	ADJ	_	Degree=Pos	_	_	_	_
25	complexes	_	NOUN	_	Number=Plur	_	_	_	_
26	may	_	AUX	_	VerbForm=Fin	_	_	_	_
27	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	pathophysiology	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	HIV	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	infection	_	NOUN	_	Number=Sing	_	_	_	_
36	by	_	SCONJ	_	_	_	_	_	_
37	augmenting	_	VERB	_	VerbForm=Ger	_	_	_	_
38	viral	_	ADJ	_	Degree=Pos	_	_	_	_
39	replication	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011403	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tobacco	_	PROPN	_	Number=Sing	_	_	_	_
2	smoke	_	NOUN	_	Number=Sing	_	_	_	_
3	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	coordinate	_	ADJ	_	Degree=Pos	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	HSF	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	effects	_	NOUN	_	Number=Plur	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
19	release	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Tobacco	_	PROPN	_	Number=Sing	_	_	_	_
2	smoke	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	TS	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	exposure	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	major	_	ADJ	_	Degree=Pos	_	_	_	_
10	risk	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	disease	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
20	smokers	_	NOUN	_	Number=Plur	_	_	_	_
21	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	depressed	_	ADJ	_	Degree=Pos	_	_	_	_
24	capacity	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	release	_	VERB	_	VerbForm=Inf	_	_	_	_
27	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	including	_	VERB	_	VerbForm=Ger	_	_	_	_
30	tumor	_	NOUN	_	Number=Sing	_	_	_	_
31	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	TNF	_	PROPN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	TS	_	PROPN	_	Number=Sing	_	_	_	_
2	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	heat	_	NOUN	_	Number=Sing	_	_	_	_
7	shock	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HS	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	stress	_	NOUN	_	Number=Sing	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	HSP	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	particular	_	ADJ	_	Degree=Pos	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	Hsp70	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	determined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	Hsp70	_	PROPN	_	Number=Sing	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	TS	_	PROPN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	HS	_	PROPN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	HSF	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	HSF	_	PROPN	_	Number=Sing	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
8	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	determined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	TS	_	PROPN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	U937	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	exposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	TS	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	activities	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	respective	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factors	_	NOUN	_	Number=Plur	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	Hsp70	_	PROPN	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
28	release	_	NOUN	_	Number=Sing	_	_	_	_
29	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	parallel	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	TS	_	PROPN	_	Number=Sing	_	_	_	_
2	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	HSF	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	Hsp70	_	PROPN	_	Number=Sing	_	_	_	_
10	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
19	release	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
4	profile	_	NOUN	_	Number=Sing	_	_	_	_
5	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	smokers	_	NOUN	_	Number=Plur	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	relate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	HSF	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	Hsp70	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
17	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1998	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011405	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Adherence	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	increase	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
8	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	B	_	X	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	increases	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	c	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	jun	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	EGR2	_	PROPN	_	Number=Sing	_	_	_	_
26	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Adherence	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	important	_	ADJ	_	Degree=Pos	_	_	_	_
5	initial	_	ADJ	_	Degree=Pos	_	_	_	_
6	step	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transition	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	tissue	_	NOUN	_	Number=Sing	_	_	_	_
17	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	augmented	_	VERB	_	Degree=Pos	_	_	_	_
8	capacity	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	generate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	growth	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	hypothesized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	adherence	_	NOUN	_	Number=Sing	_	_	_	_
5	itself	_	PRON	_	Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
6	might	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	trigger	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	sequence	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	culminating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
23	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
24	profibrotic	_	ADJ	_	Degree=Pos	_	_	_	_
25	growth	_	NOUN	_	Number=Sing	_	_	_	_
26	factors	_	NOUN	_	Number=Plur	_	_	_	_
27	such	_	ADJ	_	Degree=Pos	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	platelet	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	growth	_	NOUN	_	Number=Sing	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	subunit	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
38	[	_	PUNCT	_	_	_	_	_	_
39	B	_	X	_	_	_	_	_	_
40	]	_	PUNCT	_	_	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
44	growth	_	NOUN	_	Number=Sing	_	_	_	_
45	factor	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	beta	_	NOUN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	TGF	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	beta	_	NOUN	_	Number=Sing	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	vitro	_	NOUN	_	Number=Sing	_	_	_	_
4	adherence	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
11	increase	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	B	_	NOUN	_	_	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	peaks	_	NOUN	_	Number=Plur	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	6	_	NUM	_	NumType=Card	_	_	_	_
22	h	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	13	_	NUM	_	NumType=Card	_	_	_	_
25	d	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	increase	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	TGF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	6	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	h	_	NOUN	_	Number=Sing	_	_	_	_
5	increase	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	B	_	X	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	adherence	_	NOUN	_	Number=Sing	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	addition	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	abrogated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	when	_	ADV	_	PronType=Int	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	cytoskeletal	_	ADJ	_	Degree=Pos	_	_	_	_
25	integrity	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	compromised	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	cytochalasin	_	NOUN	_	Number=Sing	_	_	_	_
30	D.	_	PROPN	_	Number=Sing	_	_	_	_
31	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	6	_	NUM	_	NumType=Card	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	h	_	NOUN	_	Number=Sing	_	_	_	_
35	increase	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	B	_	X	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
42	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
43	unaltered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	by	_	ADP	_	_	_	_	_	_
45	adherence	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	presence	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
52	stimulus	_	ADJ	_	Degree=Pos	_	_	_	_
53	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Adherence	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	either	_	CCONJ	_	_	_	_	_	_
4	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	collagen	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	coated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	plastic	_	NOUN	_	Number=Sing	_	_	_	_
10	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	little	_	ADJ	_	Degree=Pos	_	_	_	_
12	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
13	effect	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	B	_	X	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	B	_	X	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	adherent	_	ADJ	_	Degree=Pos	_	_	_	_
11	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	increases	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	early	_	ADJ	_	Degree=Pos	_	_	_	_
21	growth	_	NOUN	_	Number=Sing	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	maximal	_	NOUN	_	Number=Sing	_	_	_	_
27	at	_	ADP	_	_	_	_	_	_
28	20	_	NUM	_	NumType=Card	_	_	_	_
29	min	_	NOUN	_	Number=Plur	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	c	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	jun	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	EGR2	_	PROPN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	maximal	_	NOUN	_	Number=Sing	_	_	_	_
40	at	_	ADP	_	_	_	_	_	_
41	6	_	NUM	_	NumType=Card	_	_	_	_
42	-	_	SYM	_	_	_	_	_	_
43	24	_	NUM	_	NumType=Card	_	_	_	_
44	h	_	NOUN	_	_	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	increase	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	jun	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	EGR2	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	not	_	ADV	_	_	_	_	_	_
12	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	also	_	ADV	_	_	_	_	_	_
17	abrogated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	cytochalasin	_	PROPN	_	Number=Sing	_	_	_	_
20	D.	_	PROPN	_	Number=Sing	_	_	_	_
21	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
22	observations	_	NOUN	_	Number=Plur	_	_	_	_
23	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	adherence	_	NOUN	_	Number=Sing	_	_	_	_
26	results	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	increases	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	EGR2	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	B	_	X	_	_	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	increases	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	EGR2	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	B	_	X	_	_	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	depend	_	VERB	_	VerbForm=Inf	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	cytoskeletal	_	ADJ	_	Degree=Pos	_	_	_	_
20	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Modulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	events	_	NOUN	_	Number=Plur	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	time	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	adherence	_	NOUN	_	Number=Sing	_	_	_	_
10	offers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	which	_	DET	_	PronType=Rel	_	_	_	_
15	differential	_	ADJ	_	Degree=Pos	_	_	_	_
16	priming	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	accomplished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011412	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	up	_	ADP	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	x	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	Bfl	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1/A1	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	CD40	_	PROPN	_	Number=Sing	_	_	_	_
21	survival	_	NOUN	_	Number=Sing	_	_	_	_
22	signaling	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CD40	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	essential	_	ADJ	_	Degree=Pos	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	thymus	_	NOUN	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	humoral	_	ADJ	_	Degree=Pos	_	_	_	_
11	immune	_	ADJ	_	Number=Sing	_	_	_	_
12	responses	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	rescuing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	B	_	NOUN	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Many	_	ADJ	_	Degree=Pos	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CD40	_	NOUN	_	Number=Sing	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	achieved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	through	_	ADP	_	_	_	_	_	_
13	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	x	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	CD40	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	antiapoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
14	molecule	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	related	_	ADJ	_	Degree=Pos	_	_	_	_
20	antiapoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
21	molecule	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	A1	_	PROPN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	Bfl	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	as	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	CD40	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	pathway	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	active	_	ADJ	_	Degree=Pos	_	_	_	_
15	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	CD40	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	up	_	ADP	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	regulation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	both	_	CCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	Bfl	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	x	_	NOUN	_	Number=Sing	_	_	_	_
37	genes	_	NOUN	_	Number=Plur	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	also	_	ADV	_	_	_	_	_	_
40	eliminated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	ability	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	CD40	_	NOUN	_	Number=Sing	_	_	_	_
45	to	_	PART	_	_	_	_	_	_
46	rescue	_	VERB	_	VerbForm=Inf	_	_	_	_
47	Fas	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	cell	_	NOUN	_	Number=Sing	_	_	_	_
51	death	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Within	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	region	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	x	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	potential	_	ADJ	_	Degree=Pos	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	sequence	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	support	_	VERB	_	VerbForm=Inf	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	x	_	NOUN	_	Number=Sing	_	_	_	_
11	protected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	Fas	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	absence	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
26	signaling	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	CD40	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	mediated	_	VERB	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	survival	_	NOUN	_	Number=Sing	_	_	_	_
12	proceeds	_	VERB	_	Number=Plur	_	_	_	_
13	through	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	up	_	ADP	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	regulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	family	_	NOUN	_	Number=Sing	_	_	_	_
27	members	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011413	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	low	_	ADJ	_	Degree=Pos	_	_	_	_
4	shear	_	ADJ	_	Degree=Pos	_	_	_	_
5	flow	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	HAEC	_	PROPN	_	Number=Sing	_	_	_	_
9	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	recently	_	ADV	_	_	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	prolonged	_	VERB	_	Degree=Pos	_	_	_	_
6	exposure	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	aortic	_	ADJ	_	Degree=Pos	_	_	_	_
10	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	HAEC	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	low	_	ADJ	_	Degree=Pos	_	_	_	_
17	shear	_	ADJ	_	Degree=Pos	_	_	_	_
18	stress	_	NOUN	_	Number=Sing	_	_	_	_
19	flow	_	NOUN	_	Number=Sing	_	_	_	_
20	patterns	_	NOUN	_	Number=Plur	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	increase	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	form	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
34	regulator	_	NOUN	_	Number=Sing	_	_	_	_
35	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
36	factor	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	investigate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	low	_	ADJ	_	Degree=Pos	_	_	_	_
8	shear	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
25	molecule	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	EC	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	Mn	_	PROPN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	that	_	SCONJ	_	_	_	_	_	_
46	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
47	activation	_	NOUN	_	Number=Sing	_	_	_	_
48	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
50	on	_	ADP	_	_	_	_	_	_
51	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
52	oxidant	_	NOUN	_	Degree=Pos	_	_	_	_
53	activity	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Before	_	ADP	_	_	_	_	_	_
2	exposure	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	low	_	ADJ	_	Degree=Pos	_	_	_	_
5	shear	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	dyn	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	cm2	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	h	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	HAEC	_	PROPN	_	Number=Sing	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	preincubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	without	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
24	pyrrolidine	_	VERB	_	Number=Sing	_	_	_	_
25	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	N-acetyl	_	PROPN	_	Number=Sing	_	_	_	_
31	-L	_	PUNCT	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	NAC	_	PROPN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
2	strongly	_	ADV	_	_	_	_	_	_
3	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	low	_	ADJ	_	Degree=Pos	_	_	_	_
5	shear	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	EC	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	Mn	_	PROPN	_	Number=Sing	_	_	_	_
24	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Paradoxically	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	NAC	_	PROPN	_	Number=Sing	_	_	_	_
4	exerted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	positive	_	ADJ	_	Degree=Pos	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	low	_	ADJ	_	Degree=Pos	_	_	_	_
10	shear	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	EC	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	Mn	_	PROPN	_	Number=Sing	_	_	_	_
21	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	only	_	ADV	_	_	_	_	_	_
24	slightly	_	ADV	_	_	_	_	_	_
25	downregulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	NAC	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
8	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	key	_	ADJ	_	Degree=Pos	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	low	_	ADJ	_	Degree=Pos	_	_	_	_
14	shear	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	that	_	DET	_	_	_	_	_	_
23	pathways	_	NOUN	_	Number=Plur	_	_	_	_
24	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
25	low	_	ADJ	_	Degree=Pos	_	_	_	_
26	shear	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	EC	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	Mn	_	PROPN	_	Number=Sing	_	_	_	_
35	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
36	may	_	AUX	_	VerbForm=Fin	_	_	_	_
37	be	_	AUX	_	VerbForm=Inf	_	_	_	_
38	differentially	_	ADV	_	_	_	_	_	_
39	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011414	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	small	_	ADJ	_	Degree=Pos	_	_	_	_
3	GTP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	binding	_	VERB	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	Rho	_	PROPN	_	Number=Sing	_	_	_	_
8	potentiates	_	VERB	_	Number=Sing	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Rho	_	PROPN	_	Number=Sing	_	_	_	_
3	family	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	small	_	ADJ	_	Degree=Pos	_	_	_	_
6	GTP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	involved	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	cytoskeletal	_	ADJ	_	Degree=Pos	_	_	_	_
17	structure	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	fate	_	NOUN	_	Number=Sing	_	_	_	_
25	development	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	transformation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	report	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	form	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Rho	_	PROPN	_	Number=Sing	_	_	_	_
14	enhances	_	NOUN	_	Number=Plur	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	presence	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
28	myristate	_	NOUN	_	Number=Sing	_	_	_	_
29	acetate	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	PMA	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	Rho	_	PROPN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	V14Rho	_	PROPN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	little	_	ADJ	_	Degree=Pos	_	_	_	_
42	or	_	CCONJ	_	_	_	_	_	_
43	no	_	DET	_	_	_	_	_	_
44	effect	_	NOUN	_	Number=Sing	_	_	_	_
45	on	_	ADP	_	_	_	_	_	_
46	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	Oct	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	1	_	NUM	_	NumType=Card	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	NF	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
56	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
57	element	_	NOUN	_	Number=Sing	_	_	_	_
58	activities	_	NOUN	_	Number=Plur	_	_	_	_
59	under	_	ADP	_	_	_	_	_	_
60	similar	_	ADJ	_	Degree=Pos	_	_	_	_
61	conditions	_	NOUN	_	Number=Plur	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	V14Rho	_	NOUN	_	Number=Sing	_	_	_	_
5	construct	_	VERB	_	Number=Sing	_	_	_	_
6	incapable	_	ADJ	_	Degree=Pos	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	membrane	_	ADJ	_	Number=Sing	_	_	_	_
9	localization	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	CAAX	_	NOUN	_	Number=Sing	_	_	_	_
12	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	abolishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	PMA	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Rho	_	PROPN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	AP	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	independent	_	ADJ	_	Degree=Pos	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	mitogen	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	pathway	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	negative	_	ADJ	_	Degree=Pos	_	_	_	_
25	MEK	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	MEK	_	PROPN	_	Number=Sing	_	_	_	_
29	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	PD98059	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
36	Rho	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	AP	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	activity	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	V14	_	PROPN	_	Number=Sing	_	_	_	_
2	Rho	_	PROPN	_	Number=Sing	_	_	_	_
3	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	strongly	_	ADV	_	_	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	protein	_	VERB	_	VerbForm=Inf	_	_	_	_
7	kinase	_	PROPN	_	Number=Sing	_	_	_	_
8	Calpha	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	PKCalpha	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vivo	_	NOUN	_	Number=Sing	_	_	_	_
14	;	_	PUNCT	_	_	_	_	_	_
15	however	_	ADV	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	deletion	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	CAAX	_	NOUN	_	Number=Sing	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	V14Rho	_	PROPN	_	Number=Sing	_	_	_	_
24	severely	_	ADV	_	_	_	_	_	_
25	diminished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
27	association	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	PKCalpha	_	PROPN	_	Number=Sing	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	effector	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Rho	_	PROPN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	observation	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	coexpression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	N-terminal	_	ADJ	_	Number=Sing	_	_	_	_
22	domain	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	PKCalpha	_	PROPN	_	Number=Sing	_	_	_	_
25	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	effects	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	Rho	_	PROPN	_	Number=Sing	_	_	_	_
31	plus	_	CCONJ	_	_	_	_	_	_
32	PMA	_	NOUN	_	Number=Sing	_	_	_	_
33	on	_	ADP	_	_	_	_	_	_
34	AP	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
38	activity	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Rho	_	PROPN	_	Number=Sing	_	_	_	_
6	potentiates	_	VERB	_	Number=Sing	_	_	_	_
7	AP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011420	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Fibrinogen	_	PROPN	_	Number=Sing	_	_	_	_
2	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Adhesion	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	PART	_	_	_	_	_	_
3	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
4	matrices	_	NOUN	_	Number=Plur	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	although	_	SCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	fully	_	ADV	_	_	_	_	_	_
18	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	exposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	fibrinous	_	ADJ	_	Degree=Pos	_	_	_	_
7	provisional	_	ADJ	_	Degree=Pos	_	_	_	_
8	matrix	_	NOUN	_	Number=Sing	_	_	_	_
9	throughout	_	ADP	_	_	_	_	_	_
10	migration	_	NOUN	_	Number=Sing	_	_	_	_
11	into	_	ADP	_	_	_	_	_	_
12	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	foci	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	so	_	ADV	_	_	_	_	_	_
16	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	study	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	undertaken	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
22	whether	_	SCONJ	_	_	_	_	_	_
23	fibrinogen	_	VERB	_	Number=Sing	_	_	_	_
24	triggers	_	NOUN	_	Number=Plur	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	factors	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	U937	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	differentiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	PMA	_	PROPN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	nonadherent	_	ADJ	_	Degree=Pos	_	_	_	_
8	culture	_	NOUN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	express	_	VERB	_	VerbForm=Inf	_	_	_	_
13	two	_	NUM	_	NumType=Card	_	_	_	_
14	fibrinogen	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
17	integrins	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	predominately	_	ADV	_	_	_	_	_	_
20	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	CD18	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	lesser	_	ADJ	_	Degree=Cmp	_	_	_	_
28	extent	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	CD11c	_	NOUN	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	CD18	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Cells	_	NOUN	_	Number=Plur	_	_	_	_
2	stimulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	fibrinogen	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	10	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	100	_	NUM	_	NumType=Card	_	_	_	_
9	microg	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	ml	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	/	_	SYM	_	_	_	_	_	_
14	Mn2	_	NOUN	_	Number=Sing	_	_	_	_
15	+	_	SYM	_	_	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	50	_	NUM	_	NumType=Card	_	_	_	_
18	microM	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	h	_	NOUN	_	Number=Plur	_	_	_	_
23	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
27	mobility	_	NOUN	_	Number=Sing	_	_	_	_
28	shift	_	NOUN	_	Number=Sing	_	_	_	_
29	assay	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	substantially	_	ADV	_	_	_	_	_	_
14	up	_	ADV	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	fibrinogen	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Fibrinogen	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	AP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	not	_	ADV	_	_	_	_	_	_
12	SP1	_	NOUN	_	Number=Sing	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	binding	_	VERB	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	CREB	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
2	mAbs	_	NOUN	_	Number=Plur	_	_	_	_
3	against	_	ADP	_	_	_	_	_	_
4	CD18	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
7	abrogated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	fibrinogen	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	U937	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
16	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	two	_	NUM	_	NumType=Card	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	sites	_	NOUN	_	Number=Plur	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
35	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	CAT	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	reporter	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Cells	_	NOUN	_	Number=Plur	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	subsequently	_	ADV	_	_	_	_	_	_
4	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	PMA	_	PROPN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	24	_	NUM	_	NumType=Card	_	_	_	_
11	h	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	CAT	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	2.6	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	fold	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	fibrinogen	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	Mn2	_	NOUN	_	Number=Sing	_	_	_	_
26	+	_	SYM	_	_	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	h	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
32	CAT	_	NOUN	_	Number=Sing	_	_	_	_
33	activity	_	NOUN	_	Number=Sing	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	3.2	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	fold	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	or	_	CCONJ	_	_	_	_	_	_
40	3	_	NUM	_	NumType=Card	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
43	with	_	ADP	_	_	_	_	_	_
44	fibrinogen	_	NOUN	_	Number=Sing	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	PMA	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
49	5.7	_	NUM	_	NumType=Card	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	CAT	_	NOUN	_	Number=Sing	_	_	_	_
54	activity	_	NOUN	_	Number=Sing	_	_	_	_
55	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
56	by	_	ADP	_	_	_	_	_	_
57	PMA	_	PROPN	_	Number=Sing	_	_	_	_
58	alone	_	ADV	_	_	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	DET	_	_	_	_	_	_
4	contact	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	fibrinogen	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	phagocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	SCONJ	_	_	_	_	_	_
17	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	CD11b	_	PROPN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	CD18	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	selective	_	ADJ	_	Degree=Pos	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
30	factors	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	including	_	VERB	_	VerbForm=Ger	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	PROPN	_	Number=Sing	_	_	_	_
36	B.	_	PROPN	_	Number=Sing	_	_	_	_
37	Document	_	NOUN	_	Number=Sing	_	_	_	_
38	0030011421	_	NUM	_	NumType=Card	_	_	_	_
39	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Alteration	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	single	_	ADJ	_	Degree=Pos	_	_	_	_
5	serine	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	basic	_	ADJ	_	Degree=Pos	_	_	_	_
9	domain	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	Barr	_	PROPN	_	Number=Sing	_	_	_	_
15	virus	_	NOUN	_	Number=Sing	_	_	_	_
16	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	separates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	functions	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	disruption	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	latency	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Barr	_	PROPN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	EBV	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	switch	_	NOUN	_	Number=Sing	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	latent	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	program	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	virus	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	member	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	bZIP	_	PROPN	_	Number=Sing	_	_	_	_
8	family	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	DNA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	activator	_	NOUN	_	Number=Sing	_	_	_	_
19	capable	_	ADJ	_	Degree=Pos	_	_	_	_
20	of	_	SCONJ	_	_	_	_	_	_
21	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	viral	_	ADJ	_	Degree=Pos	_	_	_	_
25	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
26	cycle	_	NOUN	_	Number=Sing	_	_	_	_
27	promoters	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
8	's	_	PART	_	_	_	_	_	_
9	capacity	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	disrupt	_	VERB	_	VerbForm=Inf	_	_	_	_
12	EBV	_	PROPN	_	Number=Sing	_	_	_	_
13	latency	_	NOUN	_	Number=Sing	_	_	_	_
14	resided	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	primarily	_	ADV	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	ability	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	encode	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	products	_	NOUN	_	Number=Plur	_	_	_	_
27	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
30	replication	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	generated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	point	_	NOUN	_	Number=Sing	_	_	_	_
5	mutant	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	Z	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	S186A	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	impaired	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	ability	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	;	_	PUNCT	_	_	_	_	_	_
25	however	_	ADV	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	mutation	_	NOUN	_	Number=Sing	_	_	_	_
29	abolished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	ability	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	viral	_	ADJ	_	Degree=Pos	_	_	_	_
36	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
37	cascade	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mutant	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	serine	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alanine	_	NOUN	_	Degree=Pos	_	_	_	_
11	substitution	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	DNA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	domain	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	bound	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	several	_	ADJ	_	Degree=Pos	_	_	_	_
25	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	binding	_	VERB	_	Degree=Pos	_	_	_	_
29	sites	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	from	_	ADP	_	_	_	_	_	_
34	reporters	_	NOUN	_	Number=Plur	_	_	_	_
35	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
36	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
40	promoters	_	NOUN	_	Number=Plur	_	_	_	_
41	but	_	CCONJ	_	_	_	_	_	_
42	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	not	_	PART	_	_	_	_	_	_
44	disrupt	_	VERB	_	VerbForm=Inf	_	_	_	_
45	latency	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	EBV	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	cell	_	NOUN	_	Number=Sing	_	_	_	_
51	lines	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	initiation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	EBV	_	NOUN	_	Number=Sing	_	_	_	_
7	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
8	cycle	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	function	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	addition	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	;	_	PUNCT	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	change	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	serine	_	NOUN	_	Number=Sing	_	_	_	_
26	186	_	NUM	_	NumType=Card	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	alanine	_	VERB	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	DNA	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	binding	_	VERB	_	Number=Sing	_	_	_	_
34	domain	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
37	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
39	additional	_	ADJ	_	Degree=Pos	_	_	_	_
40	function	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	uncovered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	new	_	ADJ	_	Degree=Pos	_	_	_	_
45	role	_	NOUN	_	Number=Sing	_	_	_	_
46	for	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
49	protein	_	NOUN	_	Number=Sing	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	disruption	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	EBV	_	PROPN	_	Number=Sing	_	_	_	_
54	latency	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	additional	_	ADJ	_	Degree=Pos	_	_	_	_
3	function	_	NOUN	_	Number=Sing	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	initiation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	viral	_	ADJ	_	Degree=Pos	_	_	_	_
13	life	_	NOUN	_	Number=Sing	_	_	_	_
14	cycle	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	likely	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	require	_	VERB	_	VerbForm=Inf	_	_	_	_
19	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	serine	_	NOUN	_	Number=Sing	_	_	_	_
22	186	_	NUM	_	NumType=Card	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	ZEBRA	_	PROPN	_	Number=Sing	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	may	_	AUX	_	VerbForm=Fin	_	_	_	_
30	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
31	either	_	CCONJ	_	_	_	_	_	_
32	DNA	_	PROPN	_	Number=Sing	_	_	_	_
33	recognition	_	NOUN	_	Number=Sing	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
36	activation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
39	viral	_	ADJ	_	Degree=Pos	_	_	_	_
40	promoters	_	NOUN	_	Number=Plur	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	chromatinized	_	VERB	_	Degree=Pos	_	_	_	_
44	viral	_	ADJ	_	Degree=Pos	_	_	_	_
45	episome	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011424	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	[	_	PUNCT	_	_	_	_	_	_
2	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
6	acid	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	blocks	_	NOUN	_	Number=Plur	_	_	_	_
10	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	promyelocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	stage	_	NOUN	_	Number=Sing	_	_	_	_
17	]	_	PUNCT	_	_	_	_	_	_

1	Retinoic	_	PROPN	_	Number=Sing	_	_	_	_
2	acid	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	RA	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
9	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	derivative	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	wide	_	ADJ	_	Degree=Pos	_	_	_	_
15	range	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	biological	_	ADJ	_	Degree=Pos	_	_	_	_
18	effects	_	NOUN	_	Number=Plur	_	_	_	_
19	related	_	ADJ	_	Degree=Pos	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	pleiotropic	_	ADJ	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	RA	_	PROPN	_	Number=Sing	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	RA	_	NOUN	_	Number=Sing	_	_	_	_
15	receptors	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	RARs	_	NOUN	_	Number=Plur	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	RARs	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	members	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	steroid	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
9	hormone	_	NOUN	_	Number=Sing	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	exhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
16	structure	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	possess	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	discrete	_	ADJ	_	Degree=Pos	_	_	_	_
20	DNA	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	RA	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	ligand	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	binding	_	VERB	_	Number=Sing	_	_	_	_
30	domains	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
3	system	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	RA	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	RARs	_	PROPN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	predominantly	_	ADV	_	_	_	_	_	_
10	RAR	_	PROPN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	play	_	VERB	_	VerbForm=Inf	_	_	_	_
14	key	_	ADJ	_	Degree=Pos	_	_	_	_
15	roles	_	NOUN	_	Number=Plur	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
23	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	currently	_	ADV	_	_	_	_	_	_
6	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
7	how	_	ADV	_	PronType=Int	_	_	_	_
8	RA	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	RARs	_	PROPN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	involved	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	SCONJ	_	_	_	_	_	_
14	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	normal	_	ADJ	_	Degree=Pos	_	_	_	_
16	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	make	_	VERB	_	VerbForm=Inf	_	_	_	_
3	clear	_	ADJ	_	Degree=Pos	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	roles	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	RA	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	RAR	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	normal	_	ADJ	_	Degree=Pos	_	_	_	_
14	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	introduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	construct	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	RAR	_	NOUN	_	Number=Sing	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	hRAR	_	NOUN	_	Number=Sing	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	into	_	ADP	_	_	_	_	_	_
30	murine	_	NOUN	_	Number=Sing	_	_	_	_
31	bone	_	NOUN	_	Number=Sing	_	_	_	_
32	marrow	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	retroviral	_	ADJ	_	Degree=Pos	_	_	_	_
36	vector	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	with	_	ADP	_	_	_	_	_	_
43	drug	_	NOUN	_	Number=Sing	_	_	_	_
44	resistant	_	NOUN	_	Number=Sing	_	_	_	_
45	marker	_	NOUN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	Neo	_	PROPN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	r	_	X	_	_	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
53	on	_	ADP	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	stroma	_	NOUN	_	Degree=Pos	_	_	_	_
56	cell	_	NOUN	_	Number=Sing	_	_	_	_
57	line	_	NOUN	_	Number=Sing	_	_	_	_
58	(	_	PUNCT	_	_	_	_	_	_
59	PA6	_	NOUN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	neo	_	NOUN	_	Number=Sing	_	_	_	_
62	)	_	PUNCT	_	_	_	_	_	_
63	,	_	PUNCT	_	_	_	_	_	_
64	and	_	CCONJ	_	_	_	_	_	_
65	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
66	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
67	behavior	_	NOUN	_	Number=Sing	_	_	_	_
68	of	_	ADP	_	_	_	_	_	_
69	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
70	cells	_	NOUN	_	Number=Plur	_	_	_	_
71	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	procedure	_	NOUN	_	Number=Sing	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	done	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	vitro	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Most	_	ADJ	_	Degree=Sup	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	hRAR	_	NOUN	_	Number=Sing	_	_	_	_
6	alpha	_	PROPN	_	Number=Sing	_	_	_	_
7	exhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	morphology	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	stage	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	immature	_	ADJ	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	differentiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	terminally	_	ADV	_	_	_	_	_	_
8	into	_	ADP	_	_	_	_	_	_
9	mature	_	ADJ	_	Degree=Pos	_	_	_	_
10	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	SCONJ	_	_	_	_	_	_
12	adding	_	VERB	_	VerbForm=Ger	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	RA	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	10	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	-	_	SYM	_	_	_	_	_	_
19	6	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	M	_	NOUN	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	RAR	_	PROPN	_	Number=Sing	_	_	_	_
2	alpha	_	PROPN	_	Number=Sing	_	_	_	_
3	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	able	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	into	_	ADP	_	_	_	_	_	_
11	mature	_	ADJ	_	Degree=Pos	_	_	_	_
12	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	both	_	NOUN	_	_	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	long	_	ADJ	_	Degree=Pos	_	_	_	_
18	term	_	NOUN	_	Number=Sing	_	_	_	_
19	culture	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	IL3	_	NOUN	_	Number=Sing	_	_	_	_
22	colony	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	RAR	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	alone	_	ADV	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	effective	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
15	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	RAR	_	PROPN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
24	role	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
28	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
31	precursors	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	system	_	NOUN	_	Number=Sing	_	_	_	_
3	described	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	here	_	ADV	_	PronType=Dem	_	_	_	_
5	may	_	AUX	_	VerbForm=Fin	_	_	_	_
6	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	model	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	SCONJ	_	_	_	_	_	_
11	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	essential	_	ADJ	_	Degree=Pos	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	normal	_	ADJ	_	Degree=Pos	_	_	_	_
20	bone	_	NOUN	_	Number=Sing	_	_	_	_
21	marrow	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011426	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Phosphatidylinositol	_	PROPN	_	Number=Sing	_	_	_	_
2	3	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_
5	couples	_	NOUN	_	Number=Plur	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	cycle	_	NOUN	_	Number=Sing	_	_	_	_
15	regulator	_	NOUN	_	Number=Sing	_	_	_	_
16	E2F	_	PROPN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	cycle	_	NOUN	_	Number=Sing	_	_	_	_
3	progression	_	NOUN	_	Number=Sing	_	_	_	_
4	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	critical	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	lymphoproliferation	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	immune	_	ADJ	_	Degree=Pos	_	_	_	_
24	response	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Phosphatidyl	_	PROPN	_	Number=Sing	_	_	_	_
2	inositol	_	NOUN	_	Number=Sing	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	PI3K	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	targets	_	NOUN	_	Number=Plur	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	PI3K	_	NOUN	_	Number=Sing	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	cycle	_	NOUN	_	Number=Sing	_	_	_	_
7	regulator	_	NOUN	_	Number=Sing	_	_	_	_
8	E2F	_	PROPN	_	Number=Sing	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	target	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	PI3K	_	PROPN	_	Number=Sing	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	critical	_	ADJ	_	Degree=Pos	_	_	_	_
23	signaling	_	NOUN	_	Number=Sing	_	_	_	_
24	pathway	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	eliminate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	both	_	CCONJ	_	_	_	_	_	_
4	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	Raf	_	PROPN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	MEK	_	PROPN	_	Number=Sing	_	_	_	_
9	pathways	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	E2F	_	PROPN	_	Number=Sing	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	PROPN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	B	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	PKB	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	via	_	ADP	_	_	_	_	_	_
14	PI3K	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	active	_	ADJ	_	Degree=Pos	_	_	_	_
6	PKB	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
11	E2F	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	PI3K	_	PROPN	_	Number=Sing	_	_	_	_
4	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
5	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Rb	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
12	D3	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	degradation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	p27kip1	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	establish	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
6	PI3K	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	PKB	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	link	_	NOUN	_	Number=Sing	_	_	_	_
12	between	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	teceptor	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	cycle	_	NOUN	_	Number=Sing	_	_	_	_
22	machinery	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011427	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Erythropoietin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	hemoglobin	_	NOUN	_	Number=Sing	_	_	_	_
7	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	line	_	NOUN	_	Number=Sing	_	_	_	_
15	M	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	TAT	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	M	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	TAT	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	potential	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	along	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	lineages	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	cultured	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	M	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	TAT	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	long	_	ADJ	_	Degree=Pos	_	_	_	_
8	term	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	>	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	year	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	continuous	_	ADJ	_	Degree=Pos	_	_	_	_
17	presence	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	EPO	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
27	colony	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	GM	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	CSF	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	stem	_	NOUN	_	Number=Sing	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	factor	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	SCF	_	PROPN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	long	_	ADJ	_	Degree=Pos	_	_	_	_
3	term	_	NOUN	_	Number=Sing	_	_	_	_
4	cultures	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	referred	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	M	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	TAT	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	EPO	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	M	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	TAT	_	PROPN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	GM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	CSF	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	M	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	TAT	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	SCF	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	respectively	_	ADV	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Hemoglobin	_	NOUN	_	Number=Sing	_	_	_	_
2	concentration	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	gamma	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	globin	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
9	delta	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	aminolevulinate	_	ADJ	_	Degree=Pos	_	_	_	_
12	synthase	_	NOUN	_	Number=Sing	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	significantly	_	ADV	_	_	_	_	_	_
17	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	M	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	TAT	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	EPO	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	than	_	ADP	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	M	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	TAT	_	PROPN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	GM	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	CSF	_	PROPN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	supplemented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	switched	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	GM	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CSF	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	EPO	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	hemoglobin	_	PROPN	_	Number=Sing	_	_	_	_
15	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	M	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	TAT	_	PROPN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	GM	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	CSF	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	rapidly	_	ADV	_	_	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	within	_	ADP	_	_	_	_	_	_
29	5	_	NUM	_	NumType=Card	_	_	_	_
30	h	_	NOUN	_	Number=Plur	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	level	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	GATA	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
41	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	addition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	GM	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	CSF	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	M	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	TAT	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	EPO	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	culture	_	NOUN	_	Number=Sing	_	_	_	_
19	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	amount	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	hemoglobin	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	even	_	ADV	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	presence	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	EPO	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
33	that	_	SCONJ	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	EPO	_	NOUN	_	Number=Sing	_	_	_	_
36	signal	_	NOUN	_	Number=Sing	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
39	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
40	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
42	by	_	ADP	_	_	_	_	_	_
43	GM	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	CSF	_	PROPN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
4	development	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	M	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	TAT	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	promoted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	EPO	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	GM	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	CSF	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	PronType=Rel	_	_	_	_
7	EPO	_	PROPN	_	Number=Sing	_	_	_	_
8	actively	_	ADV	_	_	_	_	_	_
9	influences	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	programming	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
18	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011432	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	renal	_	ADJ	_	Degree=Pos	_	_	_	_
9	fibrosis	_	NOUN	_	Number=Sing	_	_	_	_
10	during	_	ADP	_	_	_	_	_	_
11	ureteral	_	ADJ	_	Degree=Pos	_	_	_	_
12	obstruction	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Irrespective	_	ADJ	_	_	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	etiology	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	many	_	ADJ	_	Degree=Pos	_	_	_	_
7	kidney	_	NOUN	_	Number=Sing	_	_	_	_
8	diseases	_	NOUN	_	Number=Plur	_	_	_	_
9	result	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	fibrosis	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	tubulointerstitium	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
21	loss	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	renal	_	ADJ	_	Degree=Pos	_	_	_	_
24	function	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	any	_	DET	_	_	_	_	_	_
4	disease	_	NOUN	_	Number=Sing	_	_	_	_
5	process	_	NOUN	_	Number=Sing	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	any	_	DET	_	_	_	_	_	_
9	disease	_	NOUN	_	Number=Sing	_	_	_	_
10	process	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	progress	_	VERB	_	VerbForm=Inf	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	there	_	PRON	_	_	_	_	_	_
15	must	_	AUX	_	VerbForm=Fin	_	_	_	_
16	be	_	VERB	_	VerbForm=Inf	_	_	_	_
17	changes	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	within	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	tissue	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	family	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	involved	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	review	_	NOUN	_	Number=Sing	_	_	_	_
3	discusses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	family	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	general	_	ADJ	_	Degree=Pos	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	association	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
25	events	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	renal	_	ADJ	_	Degree=Pos	_	_	_	_
28	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	fibrosis	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011435	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	negative	_	ADJ	_	Degree=Pos	_	_	_	_
3	role	_	NOUN	_	Number=Sing	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	phosphoinositide	_	NOUN	_	Number=Sing	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
11	antigen	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	function	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	delicate	_	ADJ	_	Degree=Pos	_	_	_	_
3	balance	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	positive	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	negative	_	ADJ	_	Degree=Pos	_	_	_	_
8	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
10	during	_	ADP	_	_	_	_	_	_
11	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	determines	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	specificity	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	immune	_	ADJ	_	Degree=Pos	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Phosphoinositide	_	NOUN	_	Number=Sing	_	_	_	_
2	3-	_	NUM	_	NumType=Card	_	_	_	_
3	kinase	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	PI	_	NOUN	_	Number=Sing	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
15	set	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	receptors	_	NOUN	_	Number=Plur	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	determine	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
21	function	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	including	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
26	antigen	_	NOUN	_	Number=Sing	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	TCR	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
34	receptor	_	NOUN	_	Number=Sing	_	_	_	_
35	CD28	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	negative	_	ADJ	_	Degree=Pos	_	_	_	_
39	regulators	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
42	activation	_	NOUN	_	Number=Sing	_	_	_	_
43	such	_	ADJ	_	Degree=Pos	_	_	_	_
44	as	_	ADP	_	_	_	_	_	_
45	CTLA	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	4	_	NUM	_	NumType=Card	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	PI	_	NOUN	_	Number=Sing	_	_	_	_
2	3	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	haematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	determine	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
18	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	PI	_	NOUN	_	Number=Sing	_	_	_	_
2	3	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_
5	can	_	AUX	_	VerbForm=Fin	_	_	_	_
6	thus	_	ADV	_	_	_	_	_	_
7	dynamically	_	ADV	_	_	_	_	_	_
8	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	outcome	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	immune	_	ADJ	_	Degree=Pos	_	_	_	_
14	reactions	_	NOUN	_	Number=Plur	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	various	_	ADJ	_	Degree=Pos	_	_	_	_
17	stages	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	importance	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	PI	_	NOUN	_	Number=Sing	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	TCR	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	using	_	VERB	_	VerbForm=Ger	_	_	_	_
21	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
24	versions	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	PI	_	NOUN	_	Number=Sing	_	_	_	_
27	3	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kinase	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	Certain	_	ADJ	_	Degree=Pos	_	_	_	_
2	aspects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TCR	_	NOUN	_	Number=Sing	_	_	_	_
5	responses	_	NOUN	_	Number=Plur	_	_	_	_
6	such	_	ADJ	_	Degree=Pos	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	AP1	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	serum	_	NOUN	_	Number=Sing	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
27	forms	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	PI	_	NOUN	_	Number=Sing	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kinase	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	however	_	ADV	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	PI	_	NOUN	_	Number=Sing	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kinase	_	NOUN	_	Number=Sing	_	_	_	_
11	profoundly	_	ADV	_	_	_	_	_	_
12	influenced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
15	capacity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	'	_	PUNCT	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	'	_	PUNCT	_	_	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	AT	_	ADP	_	_	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	elicited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	TCR	_	NOUN	_	Number=Sing	_	_	_	_
34	:	_	PUNCT	_	_	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	form	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	PI	_	NOUN	_	Number=Sing	_	_	_	_
42	3	_	NUM	_	NumType=Card	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	kinase	_	NOUN	_	Number=Sing	_	_	_	_
45	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	TCR	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	NF	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	AT	_	ADP	_	_	_	_	_	_
52	responses	_	NOUN	_	Number=Plur	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	whereas	_	SCONJ	_	_	_	_	_	_
55	expression	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
58	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
59	negative	_	ADJ	_	Degree=Pos	_	_	_	_
60	mutant	_	NOUN	_	Number=Sing	_	_	_	_
61	of	_	ADP	_	_	_	_	_	_
62	PI	_	NOUN	_	Number=Sing	_	_	_	_
63	3	_	NUM	_	NumType=Card	_	_	_	_
64	-	_	PUNCT	_	_	_	_	_	_
65	kinase	_	NOUN	_	Number=Sing	_	_	_	_
66	potently	_	ADV	_	_	_	_	_	_
67	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
68	TCR	_	NOUN	_	Number=Sing	_	_	_	_
69	-	_	PUNCT	_	_	_	_	_	_
70	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
71	NF	_	PROPN	_	Number=Sing	_	_	_	_
72	-	_	PUNCT	_	_	_	_	_	_
73	AT	_	ADP	_	_	_	_	_	_
74	induction	_	NOUN	_	Number=Sing	_	_	_	_
75	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	PI	_	NOUN	_	Number=Sing	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	previously	_	ADV	_	_	_	_	_	_
13	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	PI	_	NOUN	_	Number=Sing	_	_	_	_
15	3	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	effectors	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	such	_	ADJ	_	Degree=Pos	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	positive	_	ADJ	_	Degree=Pos	_	_	_	_
28	regulator	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	PI	_	NOUN	_	Number=Sing	_	_	_	_
31	3	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kinase	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	GTPase	_	PROPN	_	Number=Sing	_	_	_	_
38	Rac	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
42	therefore	_	ADV	_	_	_	_	_	_
43	likely	_	ADJ	_	Degree=Pos	_	_	_	_
44	to	_	PART	_	_	_	_	_	_
45	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
46	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
47	novel	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	as	_	SCONJ	_	_	_	_	_	_
50	yet	_	ADV	_	_	_	_	_	_
51	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	effector	_	NOUN	_	Number=Sing	_	_	_	_
54	molecule	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	establish	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	PI	_	NOUN	_	Number=Sing	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	positively	_	ADV	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	negatively	_	ADV	_	_	_	_	_	_
14	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
15	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
16	function	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	uncover	_	VERB	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	previously	_	ADV	_	_	_	_	_	_
22	unrecognized	_	ADJ	_	Degree=Pos	_	_	_	_
23	function	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	PI	_	NOUN	_	Number=Sing	_	_	_	_
26	3	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kinase	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	T	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	selective	_	ADJ	_	Degree=Pos	_	_	_	_
35	negative	_	ADJ	_	Degree=Pos	_	_	_	_
36	regulator	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	TCR	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	signalling	_	VERB	_	Number=Sing	_	_	_	_
41	events	_	NOUN	_	Number=Plur	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	therefore	_	ADV	_	_	_	_	_	_
44	as	_	ADP	_	_	_	_	_	_
45	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
46	determinant	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
49	homeostasis	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011444	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	GATA	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
19	motifs	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Erythropoietin	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	Epo	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	primary	_	ADJ	_	Degree=Pos	_	_	_	_
8	regulator	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	acts	_	VERB	_	Number=Plur	_	_	_	_
17	by	_	SCONJ	_	_	_	_	_	_
18	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	surface	_	NOUN	_	Number=Sing	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	EpoR	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
29	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	deletion	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	transfection	_	NOUN	_	Number=Sing	_	_	_	_
7	assays	_	NOUN	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	reporter	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	constructs	_	NOUN	_	Number=Plur	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	control	_	NOUN	_	Number=Sing	_	_	_	_
17	elements	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	5	_	NUM	_	NumType=Card	_	_	_	_
21	'	_	PUNCT	_	_	_	_	_	_
22	flanking	_	VERB	_	Number=Sing	_	_	_	_
23	region	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	EpoR	_	NOUN	_	Number=Sing	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	most	_	ADJ	_	Degree=Sup	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	contained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	150	_	NUM	_	NumType=Card	_	_	_	_
14	bp	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	fragment	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
19	sites	_	NOUN	_	Number=Plur	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	AP2	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	specific	_	ADJ	_	Degree=Pos	_	_	_	_
31	GATA	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	150	_	NUM	_	NumType=Card	_	_	_	_
3	bp	_	NOUN	_	Number=Sing	_	_	_	_
4	hEpoR	_	NOUN	_	Number=Sing	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	high	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	low	_	ADJ	_	Degree=Pos	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
13	OCIM1	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	K562	_	NUM	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	respectively	_	ADV	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	reflecting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	high	_	ADJ	_	Degree=Pos	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	low	_	ADJ	_	Degree=Pos	_	_	_	_
25	levels	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
28	hEpoR	_	NOUN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GATA	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	sites	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	TATA	_	PROPN	_	Number=Sing	_	_	_	_
15	sequence	_	NOUN	_	Number=Sing	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	high	_	ADJ	_	Degree=Pos	_	_	_	_
21	level	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	other	_	ADJ	_	Degree=Pos	_	_	_	_
12	CCGCCC	_	PROPN	_	Number=Sing	_	_	_	_
13	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	non-erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	could	_	AUX	_	VerbForm=Fin	_	_	_	_
21	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	motif	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	GATA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	via	_	ADP	_	_	_	_	_	_
8	co	_	X	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	transfection	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	able	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	hEpoR	_	NOUN	_	Number=Sing	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	K562	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	non-erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	highly	_	ADV	_	_	_	_	_	_
32	active	_	ADJ	_	Degree=Pos	_	_	_	_
33	OCIM1	_	NOUN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	although	_	SCONJ	_	_	_	_	_	_
37	GATA	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
41	levels	_	NOUN	_	Number=Plur	_	_	_	_
42	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	OCIM1	_	PROPN	_	Number=Sing	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	K562	_	PROPN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	when	_	ADV	_	PronType=Int	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	mutated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	decrease	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	hEpoR	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
21	could	_	AUX	_	VerbForm=Fin	_	_	_	_
22	restore	_	VERB	_	VerbForm=Inf	_	_	_	_
23	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	SCONJ	_	_	_	_	_	_
25	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	GATA	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	levels	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	OCIM1	_	PROPN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	while	_	SCONJ	_	_	_	_	_	_
6	GATA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	EpoR	_	PROPN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	level	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	hEpoR	_	NOUN	_	Degree=Pos	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	depend	_	VERB	_	VerbForm=Inf	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	GATA	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	alone	_	ADV	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Rather	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	hEpoR	_	NOUN	_	Number=Sing	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	coordination	_	NOUN	_	Number=Sing	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	GATA	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	other	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	factors	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	including	_	VERB	_	VerbForm=Ger	_	_	_	_
23	possibly	_	ADV	_	_	_	_	_	_
24	other	_	ADJ	_	Degree=Pos	_	_	_	_
25	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	like	_	VERB	_	_	_	_	_	_
28	binding	_	VERB	_	Number=Sing	_	_	_	_
29	proteins	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
33	high	_	ADJ	_	Degree=Pos	_	_	_	_
34	level	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	tissue	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	specific	_	ADJ	_	Degree=Pos	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011445	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Alcohol	_	ADV	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Acute	_	ADJ	_	Degree=Pos	_	_	_	_
2	ethanol	_	NOUN	_	Number=Sing	_	_	_	_
3	exposure	_	NOUN	_	Number=Sing	_	_	_	_
4	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	capacity	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	immune	_	ADJ	_	Degree=Pos	_	_	_	_
10	functions	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	particularly	_	ADV	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	down	_	VERB	_	_	_	_	_	_
16	regulate	_	ADJ	_	Degree=Pos	_	_	_	_
17	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
18	production	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	effects	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	ethanol	_	NOUN	_	Number=Sing	_	_	_	_
11	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	yet	_	ADV	_	_	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Considering	_	VERB	_	VerbForm=Ger	_	_	_	_
2	that	_	DET	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	beta	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	Rel	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	common	_	ADJ	_	Degree=Pos	_	_	_	_
20	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	element	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	promoter	_	ADJ	_	Number=Sing	_	_	_	_
25	region	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
29	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	herein	_	ADV	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
35	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
38	that	_	PRON	_	PronType=Rel	_	_	_	_
39	acute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	ethanol	_	NOUN	_	Number=Sing	_	_	_	_
41	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	NF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	kappa	_	NOUN	_	Number=Sing	_	_	_	_
45	B	_	NOUN	_	Number=Sing	_	_	_	_
46	activation	_	NOUN	_	Number=Sing	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	human	_	ADJ	_	Degree=Pos	_	_	_	_
49	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Adherence	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	isolated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
4	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
7	DNA	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	PROPN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	clinically	_	ADV	_	_	_	_	_	_
3	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
4	dose	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	25	_	NUM	_	NumType=Card	_	_	_	_
7	mM	_	NOUN	_	NumType=Card	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	acute	_	ADJ	_	Degree=Pos	_	_	_	_
11	ethanol	_	NOUN	_	Number=Sing	_	_	_	_
12	treatment	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vitro	_	NOUN	_	Number=Sing	_	_	_	_
15	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	preferential	_	ADJ	_	Degree=Pos	_	_	_	_
27	induction	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	p50/p50	_	NUM	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappa	_	NOUN	_	Number=Sing	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	/	_	PUNCT	_	_	_	_	_	_
39	Rel	_	NOUN	_	Number=Sing	_	_	_	_
40	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	no	_	DET	_	_	_	_	_	_
46	induction	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	p65/p50	_	NUM	_	NumType=Card	_	_	_	_
50	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	lipopolysaccharide	_	NOUN	_	Degree=Pos	_	_	_	_
5	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	primarily	_	ADV	_	_	_	_	_	_
7	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	p65/p50	_	NUM	_	NumType=Card	_	_	_	_
10	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	result	_	VERB	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	such	_	ADJ	_	Degree=Pos	_	_	_	_
4	unique	_	ADJ	_	Degree=Pos	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
9	p50/p50	_	NOUN	_	Number=Sing	_	_	_	_
10	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	acute	_	ADJ	_	Degree=Pos	_	_	_	_
13	ethanol	_	NOUN	_	Number=Sing	_	_	_	_
14	treatment	_	NOUN	_	Number=Sing	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	result	_	VERB	_	VerbForm=Inf	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
19	rather	_	ADP	_	_	_	_	_	_
20	than	_	ADP	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
30	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
31	genes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Consequently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	physiologically	_	ADV	_	_	_	_	_	_
8	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
9	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	ethanol	_	NOUN	_	Number=Sing	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	such	_	ADJ	_	Degree=Pos	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	tumor	_	NOUN	_	Number=Sing	_	_	_	_
22	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	beta	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	6	_	NUM	_	NumType=Card	_	_	_	_
36	by	_	SCONJ	_	_	_	_	_	_
37	disrupting	_	VERB	_	VerbForm=Ger	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	kappa	_	NOUN	_	Number=Sing	_	_	_	_
41	B	_	NOUN	_	Number=Sing	_	_	_	_
42	signaling	_	NOUN	_	Number=Sing	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011448	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cloning	_	ADJ	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	functional	_	ADJ	_	Degree=Pos	_	_	_	_
4	characterization	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	early	_	ADJ	_	Degree=Pos	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	regulator	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Early	_	ADJ	_	Degree=Pos	_	_	_	_
2	B-cell	_	PROPN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	EBF	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	previously	_	ADV	_	_	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	tissue	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	stage	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	DNA	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	binding	_	VERB	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	participates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	regulation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	pre-B	_	ADJ	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	specific	_	ADJ	_	Degree=Pos	_	_	_	_
37	mb	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Partial	_	ADJ	_	Degree=Pos	_	_	_	_
2	amino	_	NOUN	_	Number=Sing	_	_	_	_
3	acid	_	NOUN	_	Number=Sing	_	_	_	_
4	sequences	_	NOUN	_	Number=Plur	_	_	_	_
5	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	EBF	_	PROPN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	isolate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
14	clones	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
19	criteria	_	NOUN	_	Number=Plur	_	_	_	_
20	encode	_	NOUN	_	Number=Sing	_	_	_	_
21	EBF	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
3	polypeptide	_	NOUN	_	Number=Sing	_	_	_	_
4	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	complexes	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	EBF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	mb	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
3	hybridized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	pre-B	_	ADJ	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	lines	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	significant	_	ADJ	_	Degree=Pos	_	_	_	_
22	levels	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	plasmacytoma	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	nonlymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	lines	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
4	EBF	_	PROPN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	transfected	_	VERB	_	Degree=Pos	_	_	_	_
7	nonlymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	strongly	_	ADV	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	reporter	_	NOUN	_	Number=Sing	_	_	_	_
14	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
15	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	functional	_	ADJ	_	Degree=Pos	_	_	_	_
17	EBF	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	sites	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	DNA	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	deletion	_	NOUN	_	Number=Sing	_	_	_	_
7	mutants	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	EBF	_	PROPN	_	Number=Sing	_	_	_	_
10	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	amino	_	ADJ	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
15	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	rich	_	ADJ	_	Degree=Pos	_	_	_	_
18	DNA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	domain	_	NOUN	_	Number=Sing	_	_	_	_
22	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
23	obvious	_	ADJ	_	Degree=Pos	_	_	_	_
24	sequence	_	NOUN	_	Number=Sing	_	_	_	_
25	similarity	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	factors	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	binding	_	VERB	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	cotranslated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	wild	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	forms	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	EBF	_	PROPN	_	Number=Sing	_	_	_	_
15	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Deletions	_	NOUN	_	Number=Plur	_	_	_	_
2	delineated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	carboxy	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	terminal	_	NOUN	_	Number=Sing	_	_	_	_
7	dimerization	_	NOUN	_	Number=Sing	_	_	_	_
8	region	_	NOUN	_	Number=Sing	_	_	_	_
9	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	repeats	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	15	_	NUM	_	NumType=Card	_	_	_	_
14	amino	_	ADJ	_	Degree=Pos	_	_	_	_
15	acids	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	similarity	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	dimerization	_	NOUN	_	Number=Sing	_	_	_	_
22	domains	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	basic	_	ADJ	_	Degree=Pos	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	helix	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	loop	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	helix	_	NOUN	_	Number=Sing	_	_	_	_
31	proteins	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	EBF	_	PROPN	_	Number=Sing	_	_	_	_
8	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	novel	_	NOUN	_	Number=Sing	_	_	_	_
11	regulator	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	B	_	ADJ	_	Degree=Pos	_	_	_	_
14	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011454	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Signal	_	ADJ	_	Number=Sing	_	_	_	_
2	transduction	_	NOUN	_	Number=Sing	_	_	_	_
3	pathways	_	NOUN	_	Number=Plur	_	_	_	_
4	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	FcepsilonRIIb	_	PROPN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	CD23	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
4	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
5	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	key	_	ADJ	_	Degree=Pos	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	initiation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	reaction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	allergic	_	ADJ	_	Degree=Pos	_	_	_	_
18	asthma	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
2	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
5	blood	_	NOUN	_	Number=Sing	_	_	_	_
6	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	when	_	ADV	_	PronType=Int	_	_	_	_
10	IgE	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	allergen	_	ADJ	_	Number=Sing	_	_	_	_
13	immune	_	ADJ	_	Number=Sing	_	_	_	_
14	complexes	_	NOUN	_	Number=Plur	_	_	_	_
15	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	CD23	_	NOUN	_	Number=Sing	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	production	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	OBJECTIVE	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	sought	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	early	_	ADJ	_	Degree=Pos	_	_	_	_
11	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	focused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	study	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	signal	_	NOUN	_	Number=Sing	_	_	_	_
10	transduction	_	NOUN	_	Number=Sing	_	_	_	_
11	pathways	_	NOUN	_	Number=Plur	_	_	_	_
12	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	CD23	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	line	_	NOUN	_	Number=Sing	_	_	_	_
23	U937	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	CD23	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	cross	_	VERB	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	U937	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	IgE	_	ADJ	_	Number=Sing	_	_	_	_
16	immune	_	NOUN	_	Number=Sing	_	_	_	_
17	complexes	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Surface	_	NOUN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	CD23	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	FACS	_	PROPN	_	Number=Sing	_	_	_	_
9	analysis	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	gel	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	shift	_	NOUN	_	Number=Sing	_	_	_	_
13	assays	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
16	blot	_	NOUN	_	Number=Sing	_	_	_	_
17	analysis	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	respectively	_	ADV	_	_	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
2	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	degradation	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	Western	_	ADJ	_	Degree=Pos	_	_	_	_
9	blot	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	main	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	involved	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	follows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	CD23	_	PROPN	_	Number=Sing	_	_	_	_
23	cross	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	linking	_	VERB	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	CD23	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
10	composed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	p65/p50	_	NUM	_	NumType=Card	_	_	_	_
13	subunits	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	translocation	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	secondary	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
13	degradation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
20	molecule	_	NOUN	_	Number=Sing	_	_	_	_
21	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Tyrosine	_	PROPN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	protein	_	VERB	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	C	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	pathways	_	NOUN	_	Number=Plur	_	_	_	_
15	mediate	_	ADJ	_	Degree=Pos	_	_	_	_
16	CD23	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	direct	_	ADJ	_	Degree=Pos	_	_	_	_
30	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
2	degradation	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	VERB	_	Number=Sing	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	translocation	_	NOUN	_	Number=Sing	_	_	_	_
9	correlate	_	VERB	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
17	TNF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1beta	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	main	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	signal	_	ADJ	_	Number=Sing	_	_	_	_
15	transduction	_	NOUN	_	Number=Sing	_	_	_	_
16	pathway	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	CD23	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011455	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Role	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Egr	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	up	_	ADP	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	regulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Fas	_	NOUN	_	Number=Sing	_	_	_	_
12	ligand	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	normal	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	aberrant	_	ADJ	_	Degree=Pos	_	_	_	_
19	double	_	ADJ	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	negative	_	ADJ	_	Degree=Pos	_	_	_	_
22	lpr	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	gld	_	ADJ	_	Degree=Pos	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	Fas	_	PROPN	_	Number=Sing	_	_	_	_
6	ligand	_	NOUN	_	Number=Sing	_	_	_	_
7	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	element	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	FLRE	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	Fas	_	PROPN	_	Number=Sing	_	_	_	_
15	ligand	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	fasL	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	Egr	_	PROPN	_	Number=Sing	_	_	_	_
23	family	_	NOUN	_	Number=Sing	_	_	_	_
24	proteins	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	Egr	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	PILOT	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	not	_	ADV	_	_	_	_	_	_
36	Egr	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	NGFI	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	A	_	PROPN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	Krox	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	24	_	NUM	_	NumType=Card	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	Tis	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	8	_	NUM	_	NumType=Card	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	Zif	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	268	_	NUM	_	NumType=Card	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
58	transcription	_	NOUN	_	Number=Sing	_	_	_	_
59	of	_	ADP	_	_	_	_	_	_
60	fasL	_	NOUN	_	Number=Sing	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	aberrant	_	NOUN	_	Degree=Pos	_	_	_	_
3	CD4	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	-)	_	SYM	_	_	_	_	_	_
6	CD8	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	-)	_	PUNCT	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	lpr	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	lpr	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	gld	_	ADJ	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	gld	_	ADJ	_	Degree=Pos	_	_	_	_
11	mice	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	mutations	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
20	Fas	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	FasL	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	respectively	_	ADV	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	constitutively	_	ADV	_	_	_	_	_	_
32	express	_	VERB	_	Degree=Pos	_	_	_	_
33	high	_	ADJ	_	Degree=Pos	_	_	_	_
34	levels	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	fasL	_	ADJ	_	Degree=Pos	_	_	_	_
37	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	prompting	_	VERB	_	VerbForm=Ger	_	_	_	_
40	us	_	PRON	_	Case=Acc|Number=Plur|Person=1|PronType=Prs	_	_	_	_
41	to	_	PART	_	_	_	_	_	_
42	ask	_	VERB	_	VerbForm=Inf	_	_	_	_
43	what	_	DET	_	PronType=Int	_	_	_	_
44	role	_	NOUN	_	Number=Sing	_	_	_	_
45	if	_	SCONJ	_	_	_	_	_	_
46	any	_	DET	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	FLRE	_	PROPN	_	Number=Sing	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	Egr	_	PROPN	_	Number=Sing	_	_	_	_
51	family	_	NOUN	_	Number=Sing	_	_	_	_
52	proteins	_	NOUN	_	Number=Plur	_	_	_	_
53	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
54	in	_	ADP	_	_	_	_	_	_
55	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
56	aberrant	_	ADJ	_	Degree=Pos	_	_	_	_
57	expression	_	NOUN	_	Number=Sing	_	_	_	_
58	of	_	ADP	_	_	_	_	_	_
59	fasL	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
2	MRL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	lpr	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	lpr	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	C3H	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	gld	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	gld	_	PROPN	_	Number=Sing	_	_	_	_
13	CD4	_	PROPN	_	Number=Sing	_	_	_	_
14	(-)	_	PUNCT	_	_	_	_	_	_
15	CD8	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	-)	_	PUNCT	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	constitutively	_	ADV	_	_	_	_	_	_
4	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	high	_	ADJ	_	Degree=Pos	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	bound	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	FLRE	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Supershift	_	PROPN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	Egr	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Egr	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	Krox	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	20	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	;	_	PUNCT	_	_	_	_	_	_
21	Egr	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	3	_	NUM	_	NumType=Card	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	normal	_	ADJ	_	Degree=Pos	_	_	_	_
4	lymph	_	NOUN	_	Number=Sing	_	_	_	_
5	node	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Egr	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	-	_	SYM	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	-	_	SYM	_	_	_	_	_	_
21	3	_	NUM	_	NumType=Card	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	egr	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	egr	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
16	A	_	PROPN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
3	Egr	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	ineffective	_	ADJ	_	Degree=Pos	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
10	Egr	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	as	_	ADV	_	_	_	_	_	_
15	potent	_	ADJ	_	Degree=Pos	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	Egr	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	in	_	SCONJ	_	_	_	_	_	_
21	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	fasL	_	ADJ	_	Degree=Pos	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	reporter	_	NOUN	_	Number=Sing	_	_	_	_
27	constructs	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	T	_	PROPN	_	Number=Sing	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	hybridomas	_	NOUN	_	Number=Plur	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	both	_	DET	_	_	_	_	_	_
38	up	_	ADV	_	_	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
42	fasL	_	ADJ	_	Degree=Pos	_	_	_	_
43	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	FasL	_	ADV	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	reporter	_	NOUN	_	Number=Sing	_	_	_	_
5	constructs	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	MRL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	lpr	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	lpr	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	C3H	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	gld	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	gld	_	PROPN	_	Number=Sing	_	_	_	_
18	CD4	_	PROPN	_	Number=Sing	_	_	_	_
19	(-)	_	PUNCT	_	_	_	_	_	_
20	CD8	_	PROPN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	-)	_	PUNCT	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	constitutively	_	ADV	_	_	_	_	_	_
5	active	_	ADJ	_	Degree=Pos	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	largely	_	ADV	_	_	_	_	_	_
12	prevented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	mutation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	critical	_	ADJ	_	Degree=Pos	_	_	_	_
18	Egr	_	NOUN	_	Number=Sing	_	_	_	_
19	family	_	NOUN	_	Number=Sing	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	element	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Egr	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	addition	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	Egr	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	FasL	_	ADJ	_	Degree=Pos	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	normal	_	ADJ	_	Degree=Pos	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	Egr	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	likely	_	ADJ	_	Degree=Pos	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	play	_	VERB	_	VerbForm=Inf	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	direct	_	ADJ	_	Degree=Pos	_	_	_	_
33	role	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	aberrant	_	NOUN	_	Degree=Pos	_	_	_	_
36	fasL	_	VERB	_	VerbForm=Inf	_	_	_	_
37	up	_	ADP	_	_	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	regulation	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	lpr	_	NOUN	_	Number=Sing	_	_	_	_
42	/	_	PUNCT	_	_	_	_	_	_
43	lpr	_	NOUN	_	Number=Sing	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	gld	_	NOUN	_	Number=Sing	_	_	_	_
46	/	_	PUNCT	_	_	_	_	_	_
47	gld	_	NOUN	_	Number=Sing	_	_	_	_
48	CD4	_	NOUN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	-)	_	PUNCT	_	_	_	_	_	_
51	CD8	_	NOUN	_	Number=Sing	_	_	_	_
52	(	_	PUNCT	_	_	_	_	_	_
53	-)	_	PUNCT	_	_	_	_	_	_
54	T	_	NOUN	_	Number=Sing	_	_	_	_
55	cells	_	NOUN	_	Number=Plur	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011458	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	TAFII	_	PROPN	_	Number=Sing	_	_	_	_
3	105	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	TFIID	_	ADJ	_	Number=Sing	_	_	_	_
11	subunit	_	NOUN	_	Number=Sing	_	_	_	_
12	related	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	hTAFII130	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	characterized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	Drosophila	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	TAF	_	NOUN	_	Number=Sing	_	_	_	_
8	subunits	_	NOUN	_	Number=Plur	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	make	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	up	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	core	_	NOUN	_	Number=Sing	_	_	_	_
14	TFIID	_	ADJ	_	Number=Sing	_	_	_	_
15	complex	_	NOUN	_	Number=Sing	_	_	_	_
16	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	all	_	DET	_	_	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	novel	_	NOUN	_	Number=Sing	_	_	_	_
12	substoichiometric	_	ADJ	_	Degree=Pos	_	_	_	_
13	TAF	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	105	_	NUM	_	NumType=Card	_	_	_	_
16	kDa	_	NOUN	_	Number=Sing	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	TFIID	_	PROPN	_	Number=Sing	_	_	_	_
22	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	other	_	ADJ	_	Degree=Pos	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	types	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
3	encoding	_	VERB	_	Number=Sing	_	_	_	_
4	hTAFII105	_	NUM	_	Number=Sing	_	_	_	_
5	reveals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	highly	_	ADV	_	_	_	_	_	_
8	conserved	_	ADJ	_	Degree=Pos	_	_	_	_
9	C	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
12	domain	_	NOUN	_	Number=Sing	_	_	_	_
13	shared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	hTAFII130	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	oTAFII110	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	while	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	N	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	terminal	_	ADJ	_	Number=Sing	_	_	_	_
24	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
25	domain	_	NOUN	_	Number=Sing	_	_	_	_
26	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	diverged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	significantly	_	ADV	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	express	_	ADJ	_	Degree=Pos	_	_	_	_
5	TAFII105	_	NUM	_	Number=Sing	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	only	_	ADV	_	_	_	_	_	_
10	B	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	significant	_	ADJ	_	Degree=Pos	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	TFIID	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	hTAFII105	_	NOUN	_	Number=Sing	_	_	_	_
5	selectively	_	ADV	_	_	_	_	_	_
6	squelches	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	some	_	DET	_	_	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	B	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	properties	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TAFII105	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	subunit	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	TFIID	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	SCONJ	_	_	_	_	_	_
20	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	subset	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	activators	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	B	_	ADJ	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011461	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CNI	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1493	_	NUM	_	NumType=Card	_	_	_	_
4	inhibits	_	NOUN	_	Number=Sing	_	_	_	_
5	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
8	tumor	_	NOUN	_	Number=Sing	_	_	_	_
9	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	suppression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	translation	_	NOUN	_	Number=Sing	_	_	_	_
15	efficiency	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	TNF	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	wide	_	ADJ	_	Degree=Pos	_	_	_	_
10	variety	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	disease	_	NOUN	_	Number=Sing	_	_	_	_
13	states	_	NOUN	_	Number=Plur	_	_	_	_
14	including	_	VERB	_	VerbForm=Ger	_	_	_	_
15	septic	_	ADJ	_	Number=Sing	_	_	_	_
16	shock	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	acute	_	ADJ	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
21	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	cachexia	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	multivalent	_	ADJ	_	Degree=Pos	_	_	_	_
5	guanylhydrazone	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	CNI	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1493	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	developed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
22	TNF	_	NOUN	_	Number=Sing	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	protect	_	VERB	_	VerbForm=Inf	_	_	_	_
26	against	_	ADP	_	_	_	_	_	_
27	tissue	_	NOUN	_	Number=Sing	_	_	_	_
28	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
31	lethality	_	NOUN	_	Number=Sing	_	_	_	_
32	[	_	PUNCT	_	_	_	_	_	_
33	Bianchi	_	PROPN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	M.	_	PROPN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	Ulrich	_	PROPN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	P.	_	PROPN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	Bloom	_	PROPN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	O.	_	PROPN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	Meistrell	_	PROPN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	M.	_	PROPN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	Zimmerman	_	PROPN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	G.A.	_	PROPN	_	Number=Sing	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	Schmidtmayerova	_	PROPN	_	Number=Sing	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	H.	_	PROPN	_	Number=Sing	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	Bukrinsky	_	PROPN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	M.	_	PROPN	_	Number=Sing	_	_	_	_
60	,	_	PUNCT	_	_	_	_	_	_
61	Donnelley	_	PROPN	_	Number=Sing	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	T.	_	PROPN	_	Number=Sing	_	_	_	_
64	,	_	PUNCT	_	_	_	_	_	_
65	Bucala	_	PROPN	_	Number=Sing	_	_	_	_
66	,	_	PUNCT	_	_	_	_	_	_
67	R.	_	PROPN	_	Number=Sing	_	_	_	_
68	,	_	PUNCT	_	_	_	_	_	_
69	Sherry	_	PROPN	_	Number=Sing	_	_	_	_
70	,	_	PUNCT	_	_	_	_	_	_
71	B.	_	PROPN	_	Number=Sing	_	_	_	_
72	,	_	PUNCT	_	_	_	_	_	_
73	Manogue	_	PROPN	_	Number=Sing	_	_	_	_
74	,	_	PUNCT	_	_	_	_	_	_
75	K.R.	_	PROPN	_	Number=Sing	_	_	_	_
76	,	_	PUNCT	_	_	_	_	_	_
77	Tortolani	_	PROPN	_	Number=Sing	_	_	_	_
78	,	_	PUNCT	_	_	_	_	_	_
79	A.J.	_	PROPN	_	Number=Sing	_	_	_	_
80	,	_	PUNCT	_	_	_	_	_	_
81	Cerami	_	PROPN	_	Number=Sing	_	_	_	_
82	,	_	PUNCT	_	_	_	_	_	_
83	A.	_	PROPN	_	Number=Sing	_	_	_	_
84	&	_	CCONJ	_	_	_	_	_	_
85	Tracey	_	PROPN	_	Number=Sing	_	_	_	_
86	,	_	PUNCT	_	_	_	_	_	_
87	K.J.	_	PROPN	_	Number=Sing	_	_	_	_
88	(	_	PUNCT	_	_	_	_	_	_
89	1995	_	NUM	_	NumType=Card	_	_	_	_
90	)	_	PUNCT	_	_	_	_	_	_
91	Mol.	_	PROPN	_	Number=Sing	_	_	_	_
92	Med.1	_	PROPN	_	Number=Sing	_	_	_	_
93	,	_	PUNCT	_	_	_	_	_	_
94	254-266	_	NUM	_	NumType=Card	_	_	_	_
95	,	_	PUNCT	_	_	_	_	_	_
96	and	_	CCONJ	_	_	_	_	_	_
97	Bianchi	_	PROPN	_	Number=Sing	_	_	_	_
98	,	_	PUNCT	_	_	_	_	_	_
99	M.	_	PROPN	_	Number=Sing	_	_	_	_
100	,	_	PUNCT	_	_	_	_	_	_
101	Bloom	_	PROPN	_	Number=Sing	_	_	_	_
102	,	_	PUNCT	_	_	_	_	_	_
103	O.	_	PROPN	_	Number=Sing	_	_	_	_
104	,	_	PUNCT	_	_	_	_	_	_
105	Raabe	_	PROPN	_	Number=Sing	_	_	_	_
106	,	_	PUNCT	_	_	_	_	_	_
107	T.	_	PROPN	_	Number=Sing	_	_	_	_
108	,	_	PUNCT	_	_	_	_	_	_
109	Cohen	_	PROPN	_	Number=Sing	_	_	_	_
110	,	_	PUNCT	_	_	_	_	_	_
111	P.	_	PROPN	_	Number=Sing	_	_	_	_
112	S.	_	PROPN	_	Number=Sing	_	_	_	_
113	,	_	PUNCT	_	_	_	_	_	_
114	Chesney	_	PROPN	_	Number=Sing	_	_	_	_
115	,	_	PUNCT	_	_	_	_	_	_
116	J.	_	PROPN	_	Number=Sing	_	_	_	_
117	,	_	PUNCT	_	_	_	_	_	_
118	Sherry	_	PROPN	_	Number=Sing	_	_	_	_
119	,	_	PUNCT	_	_	_	_	_	_
120	B.	_	PROPN	_	Number=Sing	_	_	_	_
121	,	_	PUNCT	_	_	_	_	_	_
122	Schmidtmayerova	_	PROPN	_	Number=Sing	_	_	_	_
123	,	_	PUNCT	_	_	_	_	_	_
124	H.	_	PROPN	_	Number=Sing	_	_	_	_
125	,	_	PUNCT	_	_	_	_	_	_
126	Zhang	_	PROPN	_	Number=Sing	_	_	_	_
127	,	_	PUNCT	_	_	_	_	_	_
128	X.	_	PROPN	_	Number=Sing	_	_	_	_
129	,	_	PUNCT	_	_	_	_	_	_
130	Bukrinsky	_	PROPN	_	Number=Sing	_	_	_	_
131	,	_	PUNCT	_	_	_	_	_	_
132	M.	_	PROPN	_	Number=Sing	_	_	_	_
133	,	_	PUNCT	_	_	_	_	_	_
134	Ulrich	_	PROPN	_	Number=Sing	_	_	_	_
135	,	_	PUNCT	_	_	_	_	_	_
136	P.	_	PROPN	_	Number=Sing	_	_	_	_
137	,	_	PUNCT	_	_	_	_	_	_
138	Cerami	_	PROPN	_	Number=Sing	_	_	_	_
139	,	_	PUNCT	_	_	_	_	_	_
140	A.	_	PROPN	_	Number=Sing	_	_	_	_
141	&	_	CCONJ	_	_	_	_	_	_
142	Tracey	_	PROPN	_	Number=Sing	_	_	_	_
143	,	_	PUNCT	_	_	_	_	_	_
144	J.	_	PROPN	_	Number=Sing	_	_	_	_
145	(	_	PUNCT	_	_	_	_	_	_
146	1996	_	NUM	_	NumType=Card	_	_	_	_
147	)	_	PUNCT	_	_	_	_	_	_
148	J.Exp.Med.	_	PROPN	_	Number=Sing	_	_	_	_
149	,	_	PUNCT	_	_	_	_	_	_
150	in	_	ADP	_	_	_	_	_	_
151	press	_	NOUN	_	Number=Sing	_	_	_	_
152	]	_	PUNCT	_	_	_	_	_	_
153	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	now	_	ADV	_	_	_	_	_	_
4	elucidated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	CNI	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1493	_	NUM	_	NumType=Card	_	_	_	_
12	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
13	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	here	_	ADV	_	PronType=Dem	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
21	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	through	_	ADP	_	_	_	_	_	_
23	suppression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	TNF	_	ADJ	_	Number=Sing	_	_	_	_
26	translation	_	NOUN	_	Number=Sing	_	_	_	_
27	efficiency	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	CNI	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1493	_	NUM	_	NumType=Card	_	_	_	_
4	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	neither	_	CCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	LPS	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	increases	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	TNF	_	PROPN	_	Number=Sing	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	nor	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	translocation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	NOUN	_	_	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
7	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	15	_	NUM	_	NumType=Card	_	_	_	_
10	min	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	LPS	_	NOUN	_	Number=Sing	_	_	_	_
13	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	CNI	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1493	_	NUM	_	NumType=Card	_	_	_	_
20	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	interfere	_	VERB	_	VerbForm=Inf	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	early	_	ADJ	_	Degree=Pos	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
32	regulation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	TNF	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	26	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kDa	_	NOUN	_	Number=Sing	_	_	_	_
9	membrane	_	NOUN	_	Number=Sing	_	_	_	_
10	form	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	effectively	_	ADV	_	_	_	_	_	_
15	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	CNI	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1493	_	NUM	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	evidence	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	translational	_	ADJ	_	Degree=Pos	_	_	_	_
6	suppression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	given	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	experiments	_	NOUN	_	Number=Plur	_	_	_	_
13	using	_	VERB	_	VerbForm=Ger	_	_	_	_
14	chloram	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	phenicol	_	NOUN	_	Number=Sing	_	_	_	_
17	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	CAT	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	constructs	_	NOUN	_	Number=Plur	_	_	_	_
22	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	elements	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	TNF	_	NOUN	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	involved	_	ADJ	_	Degree=Pos	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	TNF	_	PROPN	_	Number=Sing	_	_	_	_
33	translational	_	ADJ	_	Degree=Pos	_	_	_	_
34	regulation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	5	_	NUM	_	NumType=Card	_	_	_	_
4	'	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	'	_	PUNCT	_	_	_	_	_	_
8	untranslated	_	ADJ	_	Degree=Pos	_	_	_	_
9	regions	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	elicit	_	VERB	_	VerbForm=Inf	_	_	_	_
18	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
19	translational	_	ADJ	_	Degree=Pos	_	_	_	_
20	suppression	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	CNI	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1493	_	NUM	_	NumType=Card	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	target	_	NOUN	_	Number=Sing	_	_	_	_
6	through	_	ADP	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	CNI	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1493	_	NUM	_	NumType=Card	_	_	_	_
11	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	translation	_	NOUN	_	Number=Sing	_	_	_	_
14	should	_	AUX	_	VerbForm=Fin	_	_	_	_
15	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
16	insight	_	NOUN	_	Number=Sing	_	_	_	_
17	into	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011465	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cortivazol	_	ADJ	_	_	_	_	_	_
2	mediated	_	VERB	_	Degree=Pos	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	messenger	_	NOUN	_	Number=Sing	_	_	_	_
8	ribonucleic	_	NOUN	_	Number=Sing	_	_	_	_
9	acid	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	wild	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	leukemic	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	CEM	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Cortivazol	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	phenylpyrazolo	_	ADJ	_	Number=Sing	_	_	_	_
5	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	high	_	ADJ	_	Degree=Pos	_	_	_	_
8	potency	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	unusual	_	ADJ	_	Degree=Pos	_	_	_	_
11	structure	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	both	_	DET	_	_	_	_	_	_
3	wild	_	ADJ	_	Degree=Pos	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	highly	_	ADV	_	_	_	_	_	_
8	dexamethasone	_	ADJ	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	dex	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
14	clones	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	line	_	NOUN	_	Number=Sing	_	_	_	_
21	CEM	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	exposure	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	cortivazol	_	NOUN	_	Number=Sing	_	_	_	_
26	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	death	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	recently	_	ADV	_	_	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	wild	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	CEM	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	dex	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	resistant	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	GR	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	defective	_	ADJ	_	Degree=Pos	_	_	_	_
28	clone	_	NOUN	_	Number=Sing	_	_	_	_
29	ICR	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	27	_	NUM	_	NumType=Card	_	_	_	_
32	TK	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	3	_	NUM	_	NumType=Card	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	dex	_	NOUN	_	Number=Sing	_	_	_	_
37	induces	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	GR	_	NOUN	_	Number=Sing	_	_	_	_
39	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	test	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	SCONJ	_	PronType=Rel	_	_	_	_
6	cortivazol	_	ADJ	_	Number=Sing	_	_	_	_
7	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	dex	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	making	_	VERB	_	VerbForm=Ger	_	_	_	_
15	use	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	residual	_	ADJ	_	Degree=Pos	_	_	_	_
19	GR	_	NOUN	_	Number=Sing	_	_	_	_
20	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	there	_	ADV	_	PronType=Dem	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	wild	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	type	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	dex	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
30	clones	_	NOUN	_	Number=Plur	_	_	_	_
31	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	various	_	ADJ	_	Degree=Pos	_	_	_	_
35	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	cortivazol	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	induction	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	GR	_	PROPN	_	Number=Sing	_	_	_	_
42	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
43	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
44	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Cortivazol	_	PROPN	_	Number=Sing	_	_	_	_
2	significantly	_	ADV	_	_	_	_	_	_
3	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	GR	_	PROPN	_	Number=Sing	_	_	_	_
5	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	normal	_	ADJ	_	Degree=Pos	_	_	_	_
9	CEM	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	C7	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADV	_	_	_	_	_	_
13	well	_	ADV	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	two	_	NUM	_	NumType=Card	_	_	_	_
17	classes	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	dex	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
22	clones	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	although	_	SCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	dex	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
29	clones	_	NOUN	_	Number=Plur	_	_	_	_
30	needed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	at	_	ADV	_	_	_	_	_	_
32	least	_	ADV	_	Degree=Sup	_	_	_	_
33	10	_	NUM	_	NumType=Card	_	_	_	_
34	times	_	NOUN	_	Number=Plur	_	_	_	_
35	more	_	ADJ	_	_	_	_	_	_
36	cortivazol	_	ADJ	_	Degree=Pos	_	_	_	_
37	than	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	normal	_	ADJ	_	Degree=Pos	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	significant	_	ADJ	_	Degree=Pos	_	_	_	_
43	GR	_	NOUN	_	Number=Sing	_	_	_	_
44	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
45	induction	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	GR	_	NOUN	_	Number=Sing	_	_	_	_
5	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	noticed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	as	_	ADV	_	_	_	_	_	_
9	early	_	ADV	_	Degree=Pos	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	h	_	NOUN	_	Number=Plur	_	_	_	_
13	after	_	ADP	_	_	_	_	_	_
14	treatment	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	general	_	ADJ	_	Degree=Pos	_	_	_	_
3	correlation	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	GR	_	NOUN	_	Number=Sing	_	_	_	_
8	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	lysis	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	normal	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	dex	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Positive	_	ADJ	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	GR	_	NOUN	_	Number=Sing	_	_	_	_
5	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
6	might	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	one	_	NUM	_	NumType=Card	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	earliest	_	ADJ	_	Degree=Sup	_	_	_	_
12	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
13	steps	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	lysis	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	dex	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
23	CEM	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	might	_	AUX	_	VerbForm=Fin	_	_	_	_
28	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
29	as	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	marker	_	NOUN	_	Number=Sing	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	process	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	lysis	_	NOUN	_	Number=Sing	_	_	_	_
5	pathway	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	dex	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	defective	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	dex	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
19	clones	_	NOUN	_	Number=Plur	_	_	_	_
20	needed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	significantly	_	ADV	_	_	_	_	_	_
22	more	_	ADV	_	_	_	_	_	_
23	cortivazol	_	ADJ	_	Degree=Pos	_	_	_	_
24	than	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	normal	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	lysis	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011473	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	PILOT	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	putative	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	two	_	NUM	_	NumType=Card	_	_	_	_
12	signals	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	cyclosporin	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
16	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Few	_	ADJ	_	Degree=Pos	_	_	_	_
2	known	_	ADJ	_	Degree=Pos	_	_	_	_
3	genes	_	NOUN	_	Number=Plur	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	members	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	8	_	NUM	_	NumType=Card	_	_	_	_
15	family	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	interferon	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	gamma	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	T	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	only	_	ADV	_	_	_	_	_	_
27	through	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	effect	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	phorbol	_	PROPN	_	Number=Sing	_	_	_	_
33	myristic	_	PROPN	_	Number=Sing	_	_	_	_
34	acetate	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	PMA	_	PROPN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	Ca	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	2	_	NUM	_	NumType=Card	_	_	_	_
43	+	_	SYM	_	_	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	expression	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	only	_	ADV	_	_	_	_	_	_
52	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
53	genes	_	NOUN	_	Number=Plur	_	_	_	_
54	can	_	AUX	_	VerbForm=Fin	_	_	_	_
55	be	_	AUX	_	VerbForm=Inf	_	_	_	_
56	fully	_	ADV	_	_	_	_	_	_
57	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
58	by	_	ADP	_	_	_	_	_	_
59	Cyclosporin	_	PROPN	_	Number=Sing	_	_	_	_
60	A	_	PROPN	_	Number=Sing	_	_	_	_
61	(	_	PUNCT	_	_	_	_	_	_
62	CyA	_	PROPN	_	Number=Sing	_	_	_	_
63	)	_	PUNCT	_	_	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	putative	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	PILOT	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	identical	_	ADJ	_	Degree=Pos	_	_	_	_
15	dual	_	ADJ	_	Degree=Pos	_	_	_	_
16	signal	_	NOUN	_	Number=Sing	_	_	_	_
17	requirement	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	PILOT	_	PROPN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	20	_	NUM	_	NumType=Card	_	_	_	_
13	min	_	NOUN	_	Number=Plur	_	_	_	_
14	following	_	VERB	_	VerbForm=Ger	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	presence	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	fully	_	ADV	_	_	_	_	_	_
24	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	CyA	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	PILOT	_	PROPN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	calculated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	M	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	r	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	42.6	_	NUM	_	NumType=Card	_	_	_	_
13	kDa	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	three	_	NUM	_	NumType=Card	_	_	_	_
17	zinc	_	NOUN	_	Number=Sing	_	_	_	_
18	fingers	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	C2H2	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	type	_	NOUN	_	Number=Sing	_	_	_	_
24	at	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	carboxyl	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	terminus	_	NOUN	_	Number=Sing	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	highly	_	ADV	_	_	_	_	_	_
32	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	zinc	_	NOUN	_	Number=Sing	_	_	_	_
36	finger	_	NOUN	_	Number=Sing	_	_	_	_
37	regions	_	NOUN	_	Number=Plur	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	transcription	_	NOUN	_	Number=Sing	_	_	_	_
41	factors	_	NOUN	_	Number=Plur	_	_	_	_
42	EGR1	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	EGR2	_	PROPN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	pAT	_	NOUN	_	Number=Sing	_	_	_	_
48	133	_	NUM	_	NumType=Card	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	T	_	ADJ	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	fibroblasts	_	NOUN	_	Degree=Pos	_	_	_	_
9	PILOT	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	only	_	ADV	_	_	_	_	_	_
14	one	_	NUM	_	NumType=Card	_	_	_	_
15	signal	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	PMA	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	CyA	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	observation	_	NOUN	_	Number=Sing	_	_	_	_
3	directly	_	ADV	_	_	_	_	_	_
4	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	existence	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_
11	signal	_	NOUN	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	element	_	NOUN	_	Number=Sing	_	_	_	_
16	obligatory	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	some	_	DET	_	_	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	T	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	differential	_	ADJ	_	Degree=Pos	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	model	_	NOUN	_	Number=Sing	_	_	_	_
5	will	_	AUX	_	VerbForm=Fin	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	valuable	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	dissection	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	dual	_	ADJ	_	Degree=Pos	_	_	_	_
14	signal	_	NOUN	_	Number=Sing	_	_	_	_
15	pathway	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	effects	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	CyA	_	PROPN	_	Number=Sing	_	_	_	_
24	upon	_	ADP	_	_	_	_	_	_
25	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011481	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
4	configuration	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	GM	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	CSF	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	M	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	CSF	_	PROPN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	C	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	FMS	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	early	_	ADJ	_	Degree=Pos	_	_	_	_
25	growth	_	NOUN	_	Number=Sing	_	_	_	_
26	response	_	NOUN	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	EGR	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	M	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	CSF	_	NOUN	_	Number=Sing	_	_	_	_
39	genes	_	NOUN	_	Number=Plur	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	primary	_	ADJ	_	Degree=Pos	_	_	_	_
42	myelodysplastic	_	ADJ	_	Degree=Pos	_	_	_	_
43	syndromes	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
2	blood	_	NOUN	_	Number=Sing	_	_	_	_
3	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	seventeen	_	NUM	_	NumType=Card	_	_	_	_
7	patients	_	NOUN	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	myelodysplastic	_	ADJ	_	Degree=Pos	_	_	_	_
11	syndromes	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	MDS	_	X	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	advanced	_	ADJ	_	Degree=Pos	_	_	_	_
17	stage	_	NOUN	_	Number=Sing	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	enriched	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	blasts	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	1	_	X	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	karyotype	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	2	_	X	_	_	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
34	configuration	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	3	_	X	_	_	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	3	_	NUM	_	NumType=Card	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	GM	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	CSF	_	PROPN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	FMS	_	PROPN	_	Number=Sing	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	EGR	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	1	_	NUM	_	NumType=Card	_	_	_	_
54	genes	_	NOUN	_	Number=Plur	_	_	_	_
55	which	_	PRON	_	PronType=Rel	_	_	_	_
56	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
57	all	_	ADV	_	_	_	_	_	_
58	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
59	on	_	ADP	_	_	_	_	_	_
60	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
61	long	_	ADJ	_	Degree=Pos	_	_	_	_
62	arm	_	NOUN	_	Number=Sing	_	_	_	_
63	of	_	ADP	_	_	_	_	_	_
64	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
65	5	_	NUM	_	NumType=Card	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	M	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	CSF	_	PROPN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	recently	_	ADV	_	_	_	_	_	_
14	reassigned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	short	_	ADJ	_	Degree=Pos	_	_	_	_
18	arm	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	lp	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	also	_	ADV	_	_	_	_	_	_
28	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Aims	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	1	_	X	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	assess	_	VERB	_	VerbForm=Inf	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	potential	_	ADJ	_	Degree=Pos	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	maintenance	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	expansion	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	neoplastic	_	ADJ	_	Degree=Pos	_	_	_	_
28	clones	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	2	_	X	_	_	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	search	_	VERB	_	VerbForm=Inf	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	constitutional	_	ADJ	_	Degree=Pos	_	_	_	_
36	losses	_	NOUN	_	Number=Plur	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	one	_	NUM	_	NumType=Card	_	_	_	_
41	allele	_	NOUN	_	Number=Sing	_	_	_	_
42	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
45	deletion	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
49	allele	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	same	_	ADJ	_	Degree=Pos	_	_	_	_
53	genes	_	NOUN	_	Number=Plur	_	_	_	_
54	in	_	ADP	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
57	cells	_	NOUN	_	Number=Plur	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	latter	_	ADJ	_	Degree=Pos	_	_	_	_
3	issue	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	comparing	_	VERB	_	VerbForm=Ger	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	8	_	NUM	_	NumType=Card	_	_	_	_
11	cases	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
14	DNA	_	NOUN	_	Number=Sing	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	skin	_	NOUN	_	Number=Sing	_	_	_	_
17	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
20	DNA	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Eleven	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	17	_	NUM	_	NumType=Card	_	_	_	_
5	patients	_	NOUN	_	Number=Plur	_	_	_	_
6	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
8	karyotypes	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	M-CSF	_	PROPN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	6	_	NUM	_	NumType=Card	_	_	_	_
8	cases	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	FMS	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	EGR	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	latter	_	ADJ	_	Degree=Pos	_	_	_	_
25	cases	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	autocrine	_	NOUN	_	Number=Sing	_	_	_	_
3	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	growth	_	NOUN	_	Number=Sing	_	_	_	_
6	could	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	hypothesized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	only	_	ADV	_	_	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	patients	_	NOUN	_	Number=Plur	_	_	_	_
14	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	M	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	CSF	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	FMS	_	NOUN	_	Number=Sing	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	germline	_	NOUN	_	Number=Sing	_	_	_	_
3	changes	_	NOUN	_	Number=Plur	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	any	_	DET	_	_	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	genes	_	NOUN	_	Number=Plur	_	_	_	_
13	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	deregulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	genes	_	NOUN	_	Number=Plur	_	_	_	_
6	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	certain	_	ADJ	_	Degree=Pos	_	_	_	_
9	hemopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
10	growth	_	NOUN	_	Number=Sing	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	receptors	_	NOUN	_	Number=Plur	_	_	_	_
14	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	seem	_	VERB	_	VerbForm=Inf	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	major	_	ADJ	_	Degree=Pos	_	_	_	_
21	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	MDS	_	PROPN	_	Number=Sing	_	_	_	_
24	progression	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011488	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	independent	_	ADJ	_	Degree=Pos	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
7	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	Tax	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	element	_	NOUN	_	Number=Sing	_	_	_	_
14	DNA	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
4	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	three	_	NUM	_	NumType=Card	_	_	_	_
16	copies	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	imperfect	_	ADJ	_	Degree=Pos	_	_	_	_
19	repeats	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	21	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	base	_	NOUN	_	Number=Sing	_	_	_	_
25	pair	_	NOUN	_	Number=Sing	_	_	_	_
26	sequence	_	NOUN	_	Number=Sing	_	_	_	_
27	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	here	_	ADV	_	PronType=Dem	_	_	_	_
29	as	_	ADP	_	_	_	_	_	_
30	TRE	_	PROPN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	Tax	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	response	_	NOUN	_	Number=Sing	_	_	_	_
35	element	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	that	_	PRON	_	PronType=Rel	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	virally	_	ADV	_	_	_	_	_	_
43	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
45	protein	_	NOUN	_	Number=Sing	_	_	_	_
46	Tax	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	separated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	four	_	NUM	_	NumType=Card	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	C81	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	66	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	45	_	NUM	_	NumType=Card	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	immortalized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	Tax	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	T-lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
27	line	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	Salahuddin	_	PROPN	_	Number=Sing	_	_	_	_
30	et	_	X	_	_	_	_	_	_
31	al.	_	X	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	1983	_	NUM	_	NumType=Card	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	that	_	DET	_	PronType=Rel	_	_	_	_
37	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	TRE	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	DNA	_	PROPN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	none	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	which	_	PRON	_	PronType=Rel	_	_	_	_
47	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
48	identical	_	ADJ	_	Degree=Pos	_	_	_	_
49	with	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	Tax	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	protein	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	proteins	_	NOUN	_	Number=Plur	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	weights	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	about	_	ADV	_	_	_	_	_	_
9	32	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	36	_	NUM	_	NumType=Card	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	42	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	50	_	NUM	_	NumType=Card	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	110	_	NUM	_	NumType=Card	_	_	_	_
18	kD	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Four	_	NUM	_	NumType=Card	_	_	_	_
2	different	_	ADJ	_	Degree=Pos	_	_	_	_
3	methods	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	First	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	different	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	lines	_	NOUN	_	Number=Plur	_	_	_	_
7	three	_	NUM	_	NumType=Card	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	all	_	DET	_	_	_	_	_	_
10	four	_	NUM	_	NumType=Card	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	specifically	_	ADV	_	_	_	_	_	_
17	cross	_	VERB	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	UV	_	PROPN	_	Number=Sing	_	_	_	_
22	irradiation	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	radioactively	_	ADV	_	_	_	_	_	_
26	labeled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	TRE	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	DNA	_	PROPN	_	Number=Sing	_	_	_	_
30	fragment	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Second	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	TRE	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	sedimented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	glycerol	_	NOUN	_	Degree=Pos	_	_	_	_
12	density	_	NOUN	_	Number=Sing	_	_	_	_
13	gradient	_	NOUN	_	Number=Sing	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	rates	_	NOUN	_	Number=Plur	_	_	_	_
16	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	native	_	ADJ	_	Degree=Pos	_	_	_	_
21	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
22	weights	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	35	_	NUM	_	NumType=Card	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	50	_	NUM	_	NumType=Card	_	_	_	_
27	kD	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	110	_	NUM	_	NumType=Card	_	_	_	_
30	kD	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Third	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	only	_	ADV	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	50	_	NUM	_	NumType=Card	_	_	_	_
6	kD	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	retained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	biotinylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	DNA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	streptavidin	_	NOUN	_	Number=Sing	_	_	_	_
16	matrix	_	NOUN	_	Number=Sing	_	_	_	_
17	when	_	ADV	_	PronType=Int	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	DNA	_	PROPN	_	Number=Sing	_	_	_	_
20	fragment	_	NOUN	_	Number=Sing	_	_	_	_
21	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	TRE	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	DNA	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Fourth	_	ADJ	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	extensive	_	ADJ	_	Degree=Pos	_	_	_	_
4	purification	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	several	_	ADJ	_	Degree=Pos	_	_	_	_
7	cycles	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	TRE	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	affinity	_	NOUN	_	Number=Sing	_	_	_	_
13	chromatography	_	NOUN	_	Number=Sing	_	_	_	_
14	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	32	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	36	_	NUM	_	NumType=Card	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	42	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	110	_	NUM	_	NumType=Card	_	_	_	_
24	kD	_	NOUN	_	Number=Sing	_	_	_	_
25	proteins	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	less	_	ADV	_	Degree=Cmp	_	_	_	_
29	extent	_	NOUN	_	VerbForm=Inf	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	50	_	NUM	_	NumType=Card	_	_	_	_
32	kD	_	NOUN	_	Number=Sing	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	abundant	_	ADJ	_	Degree=Pos	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	75	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	80	_	NUM	_	NumType=Card	_	_	_	_
8	kD	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	competed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	out	_	ADP	_	_	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	poly	_	NOUN	_	Number=Sing	_	_	_	_
14	[	_	PUNCT	_	_	_	_	_	_
15	d	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	I	_	X	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	C	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	]	_	PUNCT	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	all	_	DET	_	_	_	_	_	_
24	reactions	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	response	_	NOUN	_	Number=Sing	_	_	_	_
5	element	_	NOUN	_	Number=Sing	_	_	_	_
6	CRE	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	TGACGTCA	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	present	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	21	_	NUM	_	NumType=Card	_	_	_	_
14	base	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	pair	_	NOUN	_	Number=Sing	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	essential	_	ADJ	_	Degree=Pos	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	TRE	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	DNA	_	NOUN	_	Number=Sing	_	_	_	_
30	interactions	_	NOUN	_	Number=Plur	_	_	_	_
31	because	_	SCONJ	_	_	_	_	_	_
32	mutation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	two	_	NUM	_	NumType=Card	_	_	_	_
36	G's	_	NOUN	_	Number=Plur	_	_	_	_
37	destroys	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
39	complex	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	result	_	NOUN	_	Number=Sing	_	_	_	_
3	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	element	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	CREB	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	involved	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	TRE	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	DNA	_	PROPN	_	Number=Sing	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	in	_	SCONJ	_	_	_	_	_	_
26	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	Tax	_	NOUN	_	Number=Sing	_	_	_	_
29	response	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011489	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	ras	_	NOUN	_	Number=Sing	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	essential	_	ADJ	_	Degree=Pos	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	T	_	NUM	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	antigen	_	NOUN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	signal	_	NOUN	_	Number=Sing	_	_	_	_
13	transduction	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	model	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	reporter	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	construct	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	agonism	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	combination	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
29	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Antigen	_	NOUN	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	signals	_	NOUN	_	Number=Plur	_	_	_	_
4	could	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	mimicked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	suboptimal	_	ADJ	_	Degree=Pos	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	C	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	PKC	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
19	esters	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	combination	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	calcium	_	NOUN	_	Number=Sing	_	_	_	_
24	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	oncogenic	_	ADJ	_	Degree=Pos	_	_	_	_
6	rats	_	NOUN	_	Number=Plur	_	_	_	_
7	obviated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	need	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	PKC	_	PROPN	_	Number=Sing	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	replace	_	VERB	_	VerbForm=Inf	_	_	_	_
17	either	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	calcium	_	NOUN	_	Number=Sing	_	_	_	_
20	signal	_	NOUN	_	Number=Sing	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	ras	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	replaced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	requirement	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	PKC	_	PROPN	_	Number=Sing	_	_	_	_
10	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	AT	_	NOUN	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
3	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
4	ras	_	NOUN	_	Number=Sing	_	_	_	_
5	mutant	_	NOUN	_	Number=Sing	_	_	_	_
6	specifically	_	ADV	_	_	_	_	_	_
7	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	agonism	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	ras	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	signaling	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	PKC	_	PROPN	_	Number=Sing	_	_	_	_
8	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	ras	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
14	ester	_	NOUN	_	Number=Sing	_	_	_	_
15	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	role	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	ras	_	NOUN	_	Number=Sing	_	_	_	_
22	upstream	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	PKC	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011491	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	unique	_	ADJ	_	Degree=Pos	_	_	_	_
12	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	simian	_	ADJ	_	Degree=Pos	_	_	_	_
15	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	variant	_	NOUN	_	Number=Sing	_	_	_	_
18	SIVsmmPBj14	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Infection	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	variant	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	simian	_	ADJ	_	Degree=Pos	_	_	_	_
7	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	SIVsmmPBj14	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	severe	_	ADJ	_	Degree=Pos	_	_	_	_
15	acute	_	ADJ	_	Degree=Pos	_	_	_	_
16	disease	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	macaques	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	designed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	functional	_	ADJ	_	Degree=Pos	_	_	_	_
9	significance	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	previously	_	ADV	_	_	_	_	_	_
12	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	mutations	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	viral	_	ADJ	_	Degree=Pos	_	_	_	_
17	long	_	ADJ	_	Degree=Pos	_	_	_	_
18	terminal	_	NOUN	_	Number=Sing	_	_	_	_
19	repeat	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	LTR	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	elucidate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	contribution	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	unique	_	ADJ	_	Degree=Pos	_	_	_	_
31	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	SIVsmmPBj14	_	PROPN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	LTR	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	SCONJ	_	_	_	_	_	_
8	using	_	VERB	_	VerbForm=Ger	_	_	_	_
9	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
10	reporter	_	NOUN	_	Number=Sing	_	_	_	_
11	constructs	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	transiently	_	ADV	_	_	_	_	_	_
15	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	into	_	ADP	_	_	_	_	_	_
17	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	wide	_	ADJ	_	Degree=Pos	_	_	_	_
4	range	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	types	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	basal	_	ADJ	_	Degree=Pos	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	LTR	_	NOUN	_	Number=Sing	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	SIVsmmPBj14	_	PROPN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	4.5	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
28	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
29	than	_	ADP	_	_	_	_	_	_
30	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	LTR	_	NOUN	_	Number=Sing	_	_	_	_
34	from	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	non-acutely	_	ADV	_	Degree=Pos	_	_	_	_
37	pathogenic	_	ADJ	_	Degree=Pos	_	_	_	_
38	strain	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
3	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	five	_	NUM	_	NumType=Card	_	_	_	_
6	point	_	NOUN	_	Number=Sing	_	_	_	_
7	mutations	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	22	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	bp	_	NOUN	_	Number=Sing	_	_	_	_
13	duplication	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	SIVsmmPBj14	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	site	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	differences	_	NOUN	_	Number=Plur	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	further	_	ADV	_	_	_	_	_	_
8	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	threefold	_	VERB	_	VerbForm=Inf	_	_	_	_
14	upon	_	ADP	_	_	_	_	_	_
15	treatment	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
20	ester	_	NOUN	_	Number=Sing	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	tumor	_	NOUN	_	Number=Sing	_	_	_	_
23	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
31	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	subunits	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Mutagenesis	_	PROPN	_	Number=Sing	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	use	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	reporter	_	NOUN	_	Number=Sing	_	_	_	_
10	construct	_	NOUN	_	Number=Sing	_	_	_	_
11	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	enhancerless	_	ADJ	_	Degree=Pos	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	effects	_	NOUN	_	Number=Plur	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	due	_	ADP	_	_	_	_	_	_
23	principally	_	ADV	_	_	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	22	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	bp	_	NOUN	_	Number=Sing	_	_	_	_
29	sequence	_	NOUN	_	Number=Sing	_	_	_	_
30	duplication	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	kappa	_	NOUN	_	Number=Sing	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	site	_	NOUN	_	Number=Sing	_	_	_	_
37	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	within	_	ADP	_	_	_	_	_	_
39	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	infectious	_	ADJ	_	Degree=Pos	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	stocks	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	isogenic	_	ADJ	_	Degree=Pos	_	_	_	_
9	except	_	ADP	_	_	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	LTR	_	PROPN	_	Number=Sing	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	generated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	LTR	_	PROPN	_	Number=Sing	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	SIVsmmPBj14	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	confer	_	VERB	_	VerbForm=Inf	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	increase	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	virus	_	NOUN	_	Number=Sing	_	_	_	_
16	replication	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	cultured	_	VERB	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Inclusion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	LTR	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
7	SIVs	_	NOUN	_	Number=Plur	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	two	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	threefold	_	ADJ	_	Degree=Pos	_	_	_	_
16	rise	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	extent	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	quiescent	_	ADJ	_	Degree=Pos	_	_	_	_
28	simian	_	ADJ	_	Degree=Pos	_	_	_	_
29	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
30	blood	_	NOUN	_	Number=Sing	_	_	_	_
31	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	PRON	_	_	_	_	_	_
9	LTR	_	PROPN	_	Number=Sing	_	_	_	_
10	mutations	_	NOUN	_	Number=Plur	_	_	_	_
11	assist	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	SIVsmmPBj14	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	SCONJ	_	_	_	_	_	_
14	responding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	efficiently	_	ADV	_	_	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	allow	_	VERB	_	VerbForm=Inf	_	_	_	_
21	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	high	_	ADJ	_	Degree=Pos	_	_	_	_
26	titers	_	NOUN	_	Number=Plur	_	_	_	_
27	during	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	acute	_	ADJ	_	Degree=Pos	_	_	_	_
30	phase	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	viral	_	ADJ	_	Degree=Pos	_	_	_	_
33	infection	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011492	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	[	_	PUNCT	_	_	_	_	_	_
2	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	biologic	_	ADJ	_	Degree=Pos	_	_	_	_
5	aspects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	interaction	_	NOUN	_	Number=Sing	_	_	_	_
8	between	_	ADP	_	_	_	_	_	_
9	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	immune	_	ADJ	_	Degree=Pos	_	_	_	_
12	systems	_	NOUN	_	Number=Plur	_	_	_	_
13	]	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	problem	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	neuro	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	immuno	_	NOUN	_	Number=Sing	_	_	_	_
8	interactions	_	NOUN	_	Number=Plur	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	level	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	trans	_	NOUN	_	Number=Plur	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	stimulating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	_	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
31	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	physico	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	chemical	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	functional	_	ADJ	_	Degree=Pos	_	_	_	_
7	parameters	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	low	_	ADJ	_	Degree=Pos	_	_	_	_
11	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	SP	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	BP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	14	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	18	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	19	_	NUM	_	NumType=Card	_	_	_	_
24	kDs	_	NOUN	_	Number=Plur	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	splenic	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	brain	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	immunized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	rats	_	NOUN	_	Number=Plur	_	_	_	_
35	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	vitro	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2mRNA	_	PROPN	_	Number=Sing	_	_	_	_
24	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	splenic	_	ADJ	_	Degree=Pos	_	_	_	_
27	T-lymphocytes	_	ADJ	_	Number=Plur	_	_	_	_
28	culture	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	normal	_	ADJ	_	Degree=Pos	_	_	_	_
31	conditions	_	NOUN	_	Number=Plur	_	_	_	_
32	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	protective	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	SP	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	BP	_	PROPN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2mRNA	_	PROPN	_	Number=Sing	_	_	_	_
13	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	stressful	_	ADJ	_	Degree=Pos	_	_	_	_
16	conditions	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	T-cells	_	PROPN	_	Number=Plur	_	_	_	_
21	treatment	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	CsA	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011494	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	7	_	NUM	_	NumType=Card	_	_	_	_
4	upregulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	SCONJ	_	_	_	_	_	_
22	enhancing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	DNA	_	PROPN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	activities	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	both	_	CCONJ	_	_	_	_	_	_
29	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	T	_	NOUN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	activator	_	NOUN	_	Number=Sing	_	_	_	_
37	protein	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	report	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	stromal	_	ADJ	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	7	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	7	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	regulation	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	T	_	PROPN	_	Number=Sing	_	_	_	_
35	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Production	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	formation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	regulation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	TCR	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	CD3	_	PROPN	_	Number=Sing	_	_	_	_
8	engagement	_	NOUN	_	Number=Sing	_	_	_	_
9	results	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	activator	_	NOUN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	AP	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
36	factor	_	NOUN	_	Number=Sing	_	_	_	_
37	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	whereas	_	SCONJ	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	CD28	_	PROPN	_	Number=Sing	_	_	_	_
45	responsive	_	ADJ	_	Number=Sing	_	_	_	_
46	complex	_	NOUN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	CD28RC	_	PROPN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
51	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	response	_	NOUN	_	Number=Sing	_	_	_	_
54	to	_	ADP	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	CD28	_	PROPN	_	Number=Sing	_	_	_	_
57	signal	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Costimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
4	/	_	PUNCT	_	_	_	_	_	_
5	anti-CD28	_	PROPN	_	Number=Sing	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	7	_	NUM	_	NumType=Card	_	_	_	_
13	induces	_	VERB	_	Number=Plur	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	fivefold	_	NOUN	_	Number=Sing	_	_	_	_
16	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
22	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	2.5	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	fold	_	NOUN	_	Number=Sing	_	_	_	_
28	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	secretion	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	rate	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	3.4	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	fold	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	effect	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	7	_	NUM	_	NumType=Card	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	part	_	ADJ	_	Degree=Pos	_	_	_	_
26	mediated	_	VERB	_	Number=Sing	_	_	_	_
27	at	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
30	level	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
4	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	7	_	NUM	_	NumType=Card	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	involve	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	DNA	_	PROPN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	60	_	NUM	_	NumType=Card	_	_	_	_
22	%	_	SYM	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	AP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	120	_	NUM	_	NumType=Card	_	_	_	_
30	%	_	SYM	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	without	_	SCONJ	_	_	_	_	_	_
34	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	activities	_	NOUN	_	Number=Plur	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	CD28RC	_	PROPN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	which	_	PRON	_	PronType=Rel	_	_	_	_
43	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
44	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	by	_	ADP	_	_	_	_	_	_
46	transfection	_	NOUN	_	Number=Sing	_	_	_	_
47	assays	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	7	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	DNA	_	NOUN	_	Number=Sing	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	cyclosporin	_	ADJ	_	Tense=Pres|VerbForm=Part	_	_	_	_
24	A	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	ADP	_	_	_	_	_	_
2	AP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	part	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
10	complex	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	7	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	signaling	_	NOUN	_	Number=Sing	_	_	_	_
21	pathway	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	involved	_	ADJ	_	Degree=Pos	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	fos	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	jun	_	NOUN	_	Number=Sing	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	which	_	PRON	_	PronType=Rel	_	_	_	_
35	AP	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	consists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011499	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	interferon	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	10	_	NUM	_	NumType=Card	_	_	_	_
12	following	_	VERB	_	VerbForm=Ger	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	lineage	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	related	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	changes	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
28	proteins	_	NOUN	_	Number=Plur	_	_	_	_
29	bound	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	IFN	_	PROPN	_	Number=Sing	_	_	_	_
32	stimulus	_	ADJ	_	Degree=Pos	_	_	_	_
33	response	_	NOUN	_	Number=Sing	_	_	_	_
34	element	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
37	sites	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	chemokine	_	ADJ	_	Number=Sing	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	following	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	lineage	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	monoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	line	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	U937	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	treatment	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	either	_	CCONJ	_	_	_	_	_	_
17	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
18	12	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	myristate	_	NOUN	_	Number=Sing	_	_	_	_
21	13	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	acetate	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	PMA	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	retinoic	_	ADJ	_	Number=Sing	_	_	_	_
29	acid	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	RA	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
36	D3	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	interferon	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	10	_	NUM	_	NumType=Card	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	IP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	10	_	NUM	_	NumType=Card	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	CXC	_	PROPN	_	Number=Sing	_	_	_	_
21	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	markedly	_	ADV	_	_	_	_	_	_
25	augmented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
29	treatment	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	PMA	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	RA	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
37	U937	_	NUM	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	but	_	CCONJ	_	_	_	_	_	_
41	only	_	ADV	_	_	_	_	_	_
42	marginally	_	ADV	_	_	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	undifferentiated	_	ADJ	_	Degree=Pos	_	_	_	_
45	or	_	CCONJ	_	_	_	_	_	_
46	VitD3	_	NUM	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	cells	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	another	_	DET	_	_	_	_	_	_
5	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
10	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	CC	_	NOUN	_	Number=Sing	_	_	_	_
17	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	FcRFgamma	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	bound	_	ADJ	_	Degree=Pos	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	gamma	_	NOUN	_	Number=Sing	_	_	_	_
33	response	_	NOUN	_	Number=Sing	_	_	_	_
34	region	_	NOUN	_	Number=Sing	_	_	_	_
35	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	similarly	_	ADV	_	_	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	less	_	ADV	_	Degree=Cmp	_	_	_	_
39	abundantly	_	ADV	_	_	_	_	_	_
40	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
43	treatment	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	PMA	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	or	_	CCONJ	_	_	_	_	_	_
48	RA	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	differentiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	U937	_	NUM	_	Number=Sing	_	_	_	_
52	cells	_	NOUN	_	Number=Plur	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
55	that	_	SCONJ	_	_	_	_	_	_
56	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
57	IP	_	NOUN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	10	_	NUM	_	NumType=Card	_	_	_	_
60	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
61	induction	_	NOUN	_	Number=Sing	_	_	_	_
62	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
63	not	_	PART	_	_	_	_	_	_
64	due	_	ADP	_	_	_	_	_	_
65	to	_	ADP	_	_	_	_	_	_
66	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
67	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
68	ability	_	NOUN	_	Number=Sing	_	_	_	_
69	of	_	ADP	_	_	_	_	_	_
70	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
71	cells	_	NOUN	_	Number=Plur	_	_	_	_
72	to	_	PART	_	_	_	_	_	_
73	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
74	to	_	ADP	_	_	_	_	_	_
75	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
76	presence	_	NOUN	_	Number=Sing	_	_	_	_
77	of	_	ADP	_	_	_	_	_	_
78	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
79	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	IP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	following	_	VERB	_	VerbForm=Ger	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	U937	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	largely	_	ADV	_	_	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	related	_	ADJ	_	Degree=Pos	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
34	changes	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	proteins	_	NOUN	_	Number=Plur	_	_	_	_
38	bound	_	ADJ	_	Degree=Pos	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	IFN	_	PROPN	_	Number=Sing	_	_	_	_
41	stimulus	_	ADJ	_	Degree=Pos	_	_	_	_
42	response	_	NOUN	_	Number=Sing	_	_	_	_
43	element	_	NOUN	_	Number=Sing	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	ISRE	_	NOUN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	kB	_	NOUN	_	Number=Sing	_	_	_	_
49	sites	_	NOUN	_	Number=Plur	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
52	that	_	SCONJ	_	_	_	_	_	_
53	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
54	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
55	proteins	_	NOUN	_	Number=Plur	_	_	_	_
56	may	_	AUX	_	VerbForm=Fin	_	_	_	_
57	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
58	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
59	IP	_	NOUN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	10	_	NUM	_	NumType=Card	_	_	_	_
62	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
63	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
64	by	_	ADP	_	_	_	_	_	_
65	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011500	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CD28	_	PROPN	_	Number=Sing	_	_	_	_
2	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	augments	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	secretion	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	lamina	_	NOUN	_	Number=Sing	_	_	_	_
11	propria	_	NOUN	_	Number=Sing	_	_	_	_
12	T	_	NUM	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	SCONJ	_	_	_	_	_	_
15	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
17	stability	_	NOUN	_	Number=Sing	_	_	_	_
18	without	_	SCONJ	_	_	_	_	_	_
19	enhancing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	pathways	_	NOUN	_	Number=Plur	_	_	_	_
3	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	lamina	_	NOUN	_	Number=Sing	_	_	_	_
8	propria	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	LP	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	different	_	ADJ	_	Degree=Pos	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	LP	_	PROPN	_	Number=Sing	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	exhibit	_	NOUN	_	Number=Sing	_	_	_	_
5	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	secretion	_	NOUN	_	Number=Sing	_	_	_	_
10	when	_	ADV	_	PronType=Int	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	through	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	CD2	_	PROPN	_	Number=Sing	_	_	_	_
15	pathway	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Coligation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CD28	_	NOUN	_	Number=Sing	_	_	_	_
4	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
7	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	secretion	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	CD28	_	PROPN	_	Number=Sing	_	_	_	_
7	augmentation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	TCR	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	signaling	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
15	blood	_	NOUN	_	Number=Sing	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	CD28	_	PROPN	_	Number=Sing	_	_	_	_
28	response	_	NOUN	_	Number=Sing	_	_	_	_
29	element	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	CD28RE	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	along	_	ADP	_	_	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
38	stability	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	characterized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	events	_	NOUN	_	Number=Plur	_	_	_	_
6	involved	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	CD28	_	PROPN	_	Number=Sing	_	_	_	_
9	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	LP	_	PROPN	_	Number=Sing	_	_	_	_
17	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	LPMC	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	LPMC	_	PROPN	_	Number=Sing	_	_	_	_
2	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	production	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	response	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	CD28	_	PROPN	_	Number=Sing	_	_	_	_
12	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	CD2	_	PROPN	_	Number=Sing	_	_	_	_
20	alone	_	ADV	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	secretion	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	paralleled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
23	stability	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
10	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	CD28	_	PROPN	_	Number=Sing	_	_	_	_
13	coligation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	CD2	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	LPMC	_	PROPN	_	Number=Sing	_	_	_	_
19	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	result	_	VERB	_	VerbForm=Inf	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	trans	_	NOUN	_	Number=Plur	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	CD28RE	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	nor	_	CCONJ	_	_	_	_	_	_
34	did	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	Western	_	ADJ	_	Degree=Pos	_	_	_	_
36	blots	_	NOUN	_	Number=Plur	_	_	_	_
37	detect	_	VERB	_	VerbForm=Inf	_	_	_	_
38	changes	_	NOUN	_	Number=Plur	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	I	_	NUM	_	NumType=Card	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappaBalpha	_	NOUN	_	Number=Sing	_	_	_	_
43	or	_	CCONJ	_	_	_	_	_	_
44	I	_	NUM	_	NumType=Card	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	kappaBbeta	_	NOUN	_	Number=Sing	_	_	_	_
47	levels	_	NOUN	_	Number=Plur	_	_	_	_
48	following	_	VERB	_	VerbForm=Ger	_	_	_	_
49	CD28	_	PROPN	_	Number=Sing	_	_	_	_
50	coligation	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CD28	_	PROPN	_	Number=Sing	_	_	_	_
4	coligation	_	NOUN	_	Number=Sing	_	_	_	_
5	fails	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	reporter	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	RE	_	ADP	_	_	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	AP	_	NOUN	_	Number=Sing	_	_	_	_
18	construct	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	CD2	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	LPMC	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	herein	_	ADV	_	_	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
9	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
10	involved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	CD28	_	PROPN	_	Number=Sing	_	_	_	_
13	cosignaling	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	secretion	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	LP	_	NOUN	_	Number=Sing	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	unique	_	ADJ	_	Degree=Pos	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
29	compartment	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	differ	_	VERB	_	VerbForm=Inf	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
34	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
37	blood	_	NOUN	_	Number=Sing	_	_	_	_
38	T	_	NOUN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	biological	_	ADJ	_	Degree=Pos	_	_	_	_
6	significance	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	different	_	ADJ	_	Degree=Pos	_	_	_	_
9	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	initiation	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	maintenance	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
22	repertoire	_	NOUN	_	Number=Sing	_	_	_	_
23	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	mucosa	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011524	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	independent	_	ADJ	_	Degree=Pos	_	_	_	_
4	turnover	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	kappa	_	VERB	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	during	_	ADP	_	_	_	_	_	_
11	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
12	adherence	_	NOUN	_	Number=Sing	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	implications	_	NOUN	_	Number=Plur	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	translational	_	ADJ	_	Degree=Pos	_	_	_	_
18	component	_	NOUN	_	Number=Sing	_	_	_	_
19	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	kappa	_	VERB	_	Number=Sing	_	_	_	_
22	B	_	PROPN	_	Number=Sing	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	MAD	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	3	_	NUM	_	NumType=Card	_	_	_	_
28	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
29	levels	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	kappa	_	VERB	_	Number=Sing	_	_	_	_
5	B	_	PROPN	_	Number=Sing	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	MAD	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	early	_	ADJ	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	response	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	variety	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	signals	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	including	_	VERB	_	VerbForm=Ger	_	_	_	_
32	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
38	myristate	_	NOUN	_	Number=Sing	_	_	_	_
39	acetate	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Within	_	ADP	_	_	_	_	_	_
2	5	_	NUM	_	NumType=Card	_	_	_	_
3	min	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
6	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	level	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	markedly	_	ADV	_	_	_	_	_	_
19	diminished	_	VERB	_	Degree=Pos	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	rapidly	_	ADV	_	_	_	_	_	_
23	replaced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	cycloheximide	_	ADJ	_	Degree=Pos	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
29	manner	_	NOUN	_	Number=Sing	_	_	_	_
30	within	_	ADP	_	_	_	_	_	_
31	20	_	NUM	_	NumType=Card	_	_	_	_
32	min	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Accompanying	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
4	turnover	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	simultaneous	_	ADJ	_	Degree=Pos	_	_	_	_
14	translocation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	related	_	ADJ	_	Degree=Pos	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	adhered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	demonstration	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	PROPN	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	kappa	_	VERB	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	MAD	_	ADJ	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	3	_	NUM	_	NumType=Card	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	other	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	types	_	NOUN	_	Number=Plur	_	_	_	_
24	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
28	increase	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	steady	_	ADJ	_	Degree=Pos	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	state	_	NOUN	_	Number=Sing	_	_	_	_
33	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
34	kappa	_	VERB	_	Number=Sing	_	_	_	_
35	B	_	PROPN	_	Number=Sing	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	/	_	PUNCT	_	_	_	_	_	_
38	MAD	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	3	_	NUM	_	NumType=Card	_	_	_	_
41	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
42	levels	_	NOUN	_	Number=Plur	_	_	_	_
43	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
44	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
45	within	_	ADP	_	_	_	_	_	_
46	30	_	NUM	_	NumType=Card	_	_	_	_
47	min	_	NOUN	_	Number=Plur	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
50	adherence	_	NOUN	_	Number=Sing	_	_	_	_
51	would	_	AUX	_	VerbForm=Fin	_	_	_	_
52	result	_	VERB	_	VerbForm=Inf	_	_	_	_
53	from	_	ADP	_	_	_	_	_	_
54	NF	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	kappa	_	PROPN	_	Number=Sing	_	_	_	_
57	B	_	NOUN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
60	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
61	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
62	of	_	ADP	_	_	_	_	_	_
63	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
64	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
65	kappa	_	VERB	_	Number=Sing	_	_	_	_
66	B	_	PROPN	_	Number=Sing	_	_	_	_
67	alpha	_	NOUN	_	Number=Sing	_	_	_	_
68	/	_	PUNCT	_	_	_	_	_	_
69	MAD	_	NOUN	_	Number=Sing	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	3	_	NUM	_	NumType=Card	_	_	_	_
72	gene	_	NOUN	_	Number=Sing	_	_	_	_
73	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	run	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	analyses	_	NOUN	_	Number=Plur	_	_	_	_
6	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	instead	_	ADV	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	while	_	SCONJ	_	_	_	_	_	_
12	several	_	ADJ	_	Degree=Pos	_	_	_	_
13	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	early	_	ADJ	_	Degree=Pos	_	_	_	_
16	cytokine	_	ADJ	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	such	_	ADJ	_	Degree=Pos	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	beta	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	beta	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	transcriptionally	_	ADV	_	_	_	_	_	_
35	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	during	_	ADP	_	_	_	_	_	_
37	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
38	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	rate	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
44	kappa	_	VERB	_	Number=Sing	_	_	_	_
45	B	_	PROPN	_	Number=Sing	_	_	_	_
46	alpha	_	NOUN	_	Number=Sing	_	_	_	_
47	/	_	PUNCT	_	_	_	_	_	_
48	MAD	_	PROPN	_	Degree=Pos	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	3	_	NUM	_	NumType=Card	_	_	_	_
51	gene	_	NOUN	_	Number=Sing	_	_	_	_
52	transcription	_	NOUN	_	Number=Sing	_	_	_	_
53	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
54	constant	_	ADJ	_	Degree=Pos	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	adherence	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	increase	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	kappa	_	VERB	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	MAD	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	3	_	NUM	_	NumType=Card	_	_	_	_
15	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
16	levels	_	NOUN	_	Number=Plur	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	also	_	ADV	_	_	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	consequence	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
24	stabilization	_	NOUN	_	Number=Sing	_	_	_	_
25	events	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	while	_	SCONJ	_	_	_	_	_	_
4	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	beta	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	kappa	_	VERB	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	MAD	_	NOUN	_	Degree=Pos	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
21	levels	_	NOUN	_	Number=Plur	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	adherent	_	ADJ	_	Degree=Pos	_	_	_	_
28	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
31	levels	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	beta	_	NOUN	_	Number=Sing	_	_	_	_
37	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
38	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	during	_	ADP	_	_	_	_	_	_
40	adherence	_	NOUN	_	Number=Sing	_	_	_	_
41	whereas	_	SCONJ	_	_	_	_	_	_
42	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
45	kappa	_	VERB	_	Number=Sing	_	_	_	_
46	B	_	PROPN	_	Number=Sing	_	_	_	_
47	alpha	_	NOUN	_	Number=Sing	_	_	_	_
48	/	_	PUNCT	_	_	_	_	_	_
49	MAD	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	3	_	NUM	_	NumType=Card	_	_	_	_
52	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
53	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
54	not	_	PART	_	_	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	interactive	_	ADJ	_	Degree=Pos	_	_	_	_
10	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
11	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	kappa	_	VERB	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	MAD	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
22	levels	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	adherent	_	ADJ	_	Degree=Pos	_	_	_	_
5	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	processing	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	decay	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	kappa	_	VERB	_	Number=Sing	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	MAD	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	3	_	NUM	_	NumType=Card	_	_	_	_
22	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	thereby	_	ADV	_	_	_	_	_	_
25	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
27	levels	_	NOUN	_	Number=Plur	_	_	_	_
28	without	_	SCONJ	_	_	_	_	_	_
29	stimulating	_	VERB	_	VerbForm=Ger	_	_	_	_
30	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
31	kappa	_	VERB	_	Number=Sing	_	_	_	_
32	B	_	PROPN	_	Number=Sing	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	MAD	_	ADJ	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	3	_	NUM	_	NumType=Card	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	since	_	SCONJ	_	_	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
8	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	kappa	_	VERB	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	MAD	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
21	without	_	SCONJ	_	_	_	_	_	_
22	stimulating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
24	kappa	_	VERB	_	Number=Sing	_	_	_	_
25	B	_	PROPN	_	Number=Sing	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	MAD	_	ADJ	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
35	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	that	_	SCONJ	_	_	_	_	_	_
37	low	_	ADJ	_	Degree=Pos	_	_	_	_
38	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
39	levels	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
42	kappa	_	VERB	_	Number=Sing	_	_	_	_
43	B	_	PROPN	_	Number=Sing	_	_	_	_
44	alpha	_	NOUN	_	Number=Sing	_	_	_	_
45	/	_	PUNCT	_	_	_	_	_	_
46	MAD	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	3	_	NUM	_	NumType=Card	_	_	_	_
49	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
50	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
51	maintained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	by	_	ADP	_	_	_	_	_	_
53	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
54	translation	_	NOUN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
57	degradation	_	NOUN	_	Number=Sing	_	_	_	_
58	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011530	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cloning	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	characterization	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	subunit	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	binding	_	VERB	_	Number=Sing	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	involvement	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	small	_	ADJ	_	Degree=Pos	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	RNA	_	NOUN	_	Number=Sing	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	RNA	_	PROPN	_	Number=Sing	_	_	_	_
29	polymerases	_	NOUN	_	Number=Plur	_	_	_	_
30	II	_	NUM	_	NumType=Card	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	III	_	NUM	_	NumType=Card	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	element	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	PSE	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	PTF	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	PSE	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	both	_	CCONJ	_	_	_	_	_	_
22	RNA	_	PROPN	_	Number=Sing	_	_	_	_
23	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
24	II	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	RNA	_	PROPN	_	Number=Sing	_	_	_	_
28	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
29	III	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	transcribed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
33	small	_	ADJ	_	Degree=Pos	_	_	_	_
34	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
35	RNA	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	snRNA	_	PROPN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	genes	_	NOUN	_	Number=Plur	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	essential	_	ADJ	_	Degree=Pos	_	_	_	_
43	for	_	ADP	_	_	_	_	_	_
44	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
45	transcription	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	purification	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	PTF	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	complex	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	four	_	NUM	_	NumType=Card	_	_	_	_
14	subunits	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
19	cloning	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	characterization	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	PTF	_	NOUN	_	Number=Sing	_	_	_	_
24	gamma	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	delta	_	NOUN	_	Number=Sing	_	_	_	_
27	subunits	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	isolation	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
11	encoding	_	VERB	_	Number=Sing	_	_	_	_
12	PTF	_	NOUN	_	Number=Sing	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	as	_	ADV	_	_	_	_	_	_
16	well	_	ADV	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	functional	_	ADJ	_	Degree=Pos	_	_	_	_
19	studies	_	NOUN	_	Number=Plur	_	_	_	_
20	using	_	VERB	_	VerbForm=Ger	_	_	_	_
21	anti-PTF	_	ADJ	_	Degree=Pos	_	_	_	_
22	beta	_	NOUN	_	Number=Sing	_	_	_	_
23	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Native	_	ADJ	_	Degree=Pos	_	_	_	_
2	PTF	_	PROPN	_	Number=Sing	_	_	_	_
3	beta	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	either	_	CCONJ	_	_	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	fractions	_	NOUN	_	Number=Plur	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	PTF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	Oct	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	DNA	_	NOUN	_	Number=Sing	_	_	_	_
18	complex	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	can	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
25	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
26	raised	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	against	_	ADP	_	_	_	_	_	_
28	recombinant	_	ADJ	_	Number=Sing	_	_	_	_
29	PTF	_	PROPN	_	Number=Sing	_	_	_	_
30	beta	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Immunodepletion	_	PROPN	_	Number=Sing	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	PTF	_	PROPN	_	Number=Sing	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	both	_	DET	_	_	_	_	_	_
13	classes	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	snRNA	_	ADJ	_	Degree=Pos	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	vitro	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
5	analyses	_	NOUN	_	Number=Plur	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	similar	_	ADJ	_	Degree=Pos	_	_	_	_
11	molar	_	ADJ	_	Degree=Pos	_	_	_	_
12	amounts	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	TATA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	TBP	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	TFIIIB90	_	PROPN	_	Number=Sing	_	_	_	_
23	can	_	AUX	_	VerbForm=Fin	_	_	_	_
24	weakly	_	ADV	_	_	_	_	_	_
25	associate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	PTF	_	NOUN	_	Number=Sing	_	_	_	_
28	at	_	ADP	_	_	_	_	_	_
29	low	_	ADJ	_	Degree=Pos	_	_	_	_
30	salt	_	NOUN	_	Number=Sing	_	_	_	_
31	conditions	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	but	_	CCONJ	_	_	_	_	_	_
34	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
35	association	_	NOUN	_	Number=Sing	_	_	_	_
36	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	dramatically	_	ADV	_	_	_	_	_	_
38	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	at	_	ADP	_	_	_	_	_	_
40	high	_	ADJ	_	Degree=Pos	_	_	_	_
41	salt	_	NOUN	_	Number=Sing	_	_	_	_
42	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Along	_	ADP	_	_	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	previous	_	ADJ	_	Degree=Pos	_	_	_	_
5	demonstration	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	both	_	CCONJ	_	_	_	_	_	_
8	physical	_	ADJ	_	Degree=Pos	_	_	_	_
9	interactions	_	NOUN	_	Number=Plur	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	PTF	_	NOUN	_	Number=Sing	_	_	_	_
12	gamma	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	PTF	_	PROPN	_	Number=Sing	_	_	_	_
15	delta	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	TBP	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	involvement	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	TFIIIB90	_	PROPN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	class	_	NOUN	_	Number=Sing	_	_	_	_
28	III	_	PROPN	_	NumType=Card	_	_	_	_
29	snRNA	_	PROPN	_	Number=Sing	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
33	results	_	NOUN	_	Number=Plur	_	_	_	_
34	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	notion	_	NOUN	_	Number=Sing	_	_	_	_
39	that	_	SCONJ	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	TBP	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
44	complex	_	NOUN	_	Number=Sing	_	_	_	_
45	related	_	ADJ	_	Degree=Pos	_	_	_	_
46	to	_	ADP	_	_	_	_	_	_
47	TFIIIB	_	PROPN	_	Number=Sing	_	_	_	_
48	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
50	for	_	ADP	_	_	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	transcription	_	NOUN	_	Number=Sing	_	_	_	_
53	of	_	ADP	_	_	_	_	_	_
54	class	_	NOUN	_	Number=Sing	_	_	_	_
55	III	_	PROPN	_	NumType=Card	_	_	_	_
56	snRNA	_	PROPN	_	Number=Sing	_	_	_	_
57	genes	_	NOUN	_	Number=Plur	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	and	_	CCONJ	_	_	_	_	_	_
60	acts	_	VERB	_	Number=Plur	_	_	_	_
61	through	_	ADP	_	_	_	_	_	_
62	weak	_	ADJ	_	Degree=Pos	_	_	_	_
63	interaction	_	NOUN	_	Number=Sing	_	_	_	_
64	with	_	ADP	_	_	_	_	_	_
65	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
66	four	_	NUM	_	NumType=Card	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	subunit	_	NOUN	_	Number=Sing	_	_	_	_
69	PTF	_	NOUN	_	Number=Sing	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011534	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	block	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	alpha,25	_	NUM	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_

1	D3	_	NUM	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	VERB	_	Degree=Pos	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Elements	_	NOUN	_	Number=Plur	_	_	_	_
2	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	steroid	_	NOUN	_	Number=Sing	_	_	_	_
6	hormone	_	NOUN	_	Number=Sing	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	alpha,25	_	NUM	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
11	D3	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	alpha,25	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	OH	_	NOUN	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	D3	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	biological	_	ADJ	_	Degree=Pos	_	_	_	_
26	response	_	NOUN	_	Number=Sing	_	_	_	_
27	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	presence	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	specific	_	ADJ	_	Degree=Pos	_	_	_	_
32	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
33	receptors	_	NOUN	_	Number=Plur	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
36	D3	_	NOUN	_	Number=Sing	_	_	_	_
37	receptors	_	NOUN	_	Number=Plur	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	VDR	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	modulation	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	gene	_	NOUN	_	Number=Sing	_	_	_	_
46	expression	_	NOUN	_	Number=Sing	_	_	_	_
47	via	_	ADP	_	_	_	_	_	_
48	hormone	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	receptor	_	NOUN	_	Number=Sing	_	_	_	_
52	binding	_	NOUN	_	Number=Sing	_	_	_	_
53	to	_	ADP	_	_	_	_	_	_
54	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
55	regions	_	NOUN	_	Number=Plur	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	target	_	NOUN	_	Number=Sing	_	_	_	_
58	genes	_	NOUN	_	Number=Plur	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	parameters	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	normal	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	Barr	_	PROPN	_	Number=Sing	_	_	_	_
11	virus	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	immortalized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	25	_	NUM	_	NumType=Card	_	_	_	_
24	-(	_	PUNCT	_	_	_	_	_	_
25	OH	_	NOUN	_	_	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	2D3	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	T	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
36	lineages	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
3	tonsillar	_	ADJ	_	Degree=Pos	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	express	_	VERB	_	VerbForm=Inf	_	_	_	_
9	VDR	_	PROPN	_	Number=Sing	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	4	_	NUM	_	NumType=Card	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	VDR	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	absence	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	exogenously	_	ADV	_	_	_	_	_	_
27	supplemented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	25	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	OH	_	INTJ	_	_	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	2D3	_	NUM	_	NumType=Card	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	indicators	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	hormone	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	mediated	_	VERB	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	modulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	CD23	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	common	_	ADJ	_	Degree=Pos	_	_	_	_
17	B	_	NOUN	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	surface	_	NOUN	_	Number=Sing	_	_	_	_
22	antigen	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	24	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	hydroxylase	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	1	_	NUM	_	NumType=Card	_	_	_	_
2	alpha,25	_	NOUN	_	Number=Sing	_	_	_	_
3	-(	_	PUNCT	_	_	_	_	_	_
4	OH	_	INTJ	_	_	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	2D3	_	NUM	_	NumType=Card	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	CD23	_	PROPN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	U937	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	yet	_	CCONJ	_	_	_	_	_	_
15	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
18	CD23	_	PROPN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	B	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	25	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	OH	_	NOUN	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	2D3	_	NUM	_	Number=Sing	_	_	_	_
12	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	24	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	hydroxylase	_	NOUN	_	Number=Sing	_	_	_	_
16	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	metabolic	_	ADJ	_	Degree=Pos	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	U937	_	NUM	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	lectin	_	VERB	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	T	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	yet	_	CCONJ	_	_	_	_	_	_
33	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
36	24	_	NUM	_	NumType=Card	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	hydroxylase	_	NOUN	_	Number=Sing	_	_	_	_
39	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
40	or	_	CCONJ	_	_	_	_	_	_
41	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
42	metabolic	_	ADJ	_	Degree=Pos	_	_	_	_
43	activity	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	B	_	ADJ	_	Number=Sing	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	although	_	SCONJ	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	express	_	VERB	_	VerbForm=Inf	_	_	_	_
11	VDR	_	PROPN	_	Number=Sing	_	_	_	_
12	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	protein	_	VERB	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
17	exhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	functional	_	ADJ	_	Degree=Pos	_	_	_	_
20	block	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
23	D	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	regulation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011537	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tandem	_	NOUN	_	Number=Sing	_	_	_	_
2	AP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	within	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	beta-globin	_	NOUN	_	Number=Sing	_	_	_	_
12	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
13	control	_	NOUN	_	Number=Sing	_	_	_	_
14	region	_	NOUN	_	Number=Sing	_	_	_	_
15	function	_	NOUN	_	Number=Sing	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
19	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	powerful	_	ADJ	_	Degree=Pos	_	_	_	_
3	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
6	mapped	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	18	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	bp	_	NOUN	_	Number=Sing	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	segment	_	NOUN	_	Number=Sing	_	_	_	_
14	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	11	_	NUM	_	NumType=Card	_	_	_	_
16	kb	_	NOUN	_	Number=Sing	_	_	_	_
17	5	_	NUM	_	NumType=Card	_	_	_	_
18	'	_	PUNCT	_	Number=Plur	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	globin	_	ADJ	_	Degree=Pos	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	within	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
29	control	_	NOUN	_	Number=Sing	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	locus	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
34	region	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	K562	_	NUM	_	NumType=Card	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	erythroleukemia	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	globin	_	NOUN	_	Degree=Pos	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	170	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
25	over	_	ADP	_	_	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	enhancerless	_	ADJ	_	Degree=Pos	_	_	_	_
28	construct	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
3	consists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	tandem	_	NOUN	_	Number=Sing	_	_	_	_
6	AP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	sites	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	phased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	10	_	NUM	_	NumType=Card	_	_	_	_
15	bp	_	NOUN	_	Number=Sing	_	_	_	_
16	apart	_	ADV	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	both	_	ADV	_	_	_	_	_	_
21	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	full	_	ADJ	_	Degree=Pos	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	extracts	_	NOUN	_	Number=Plur	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	high	_	ADJ	_	Degree=Pos	_	_	_	_
15	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
16	weight	_	NOUN	_	Number=Sing	_	_	_	_
17	complex	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	formation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	complex	_	NOUN	_	Number=Sing	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	correlates	_	VERB	_	Number=Plur	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
17	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
5	may	_	AUX	_	VerbForm=Fin	_	_	_	_
6	have	_	VERB	_	VerbForm=Inf	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	increase	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	globin	_	ADJ	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	characterizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
19	maturation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Enhancer	_	NOUN	_	Number=Sing	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	complex	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	jun	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	fos	_	VERB	_	Number=Sing	_	_	_	_
20	families	_	NOUN	_	Number=Plur	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	tandem	_	VERB	_	Number=Sing	_	_	_	_
23	AP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	consensus	_	NOUN	_	Number=Sing	_	_	_	_
27	sequences	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011538	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	Nef	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibits	_	NOUN	_	Number=Sing	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	can	_	AUX	_	VerbForm=Fin	_	_	_	_
12	establish	_	VERB	_	VerbForm=Inf	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	latent	_	ADJ	_	Degree=Pos	_	_	_	_
17	infection	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	CD4	_	PROPN	_	Number=Sing	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	W.C.Greene	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	N.Engl.J.	_	PROPN	_	Number=Sing	_	_	_	_
7	Med.324:308-317	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	1991	_	NUM	_	NumType=Card	_	_	_	_
10	;	_	PUNCT	_	_	_	_	_	_
11	S.M.Schnittman	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	M.C.Psallidopoulos	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	H.C.	_	PROPN	_	Number=Sing	_	_	_	_
16	Lane	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	L.Thompson	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	M.Baseler	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	F.Massari	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	C.H.Fox	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	N.P.	_	PROPN	_	Number=Sing	_	_	_	_
27	Salzman	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	A.S.	_	PROPN	_	Number=Sing	_	_	_	_
31	Fauci	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	Science	_	PROPN	_	Number=Sing	_	_	_	_
34	245:305-308	_	NUM	_	NumType=Card	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	1989	_	NUM	_	NumType=Card	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Production	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HIV	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	latently	_	ADV	_	_	_	_	_	_
8	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	host	_	ADJ	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
16	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	T.Folks	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	D.M.Powell	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	M.M.Lightfoote	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	S.	_	PROPN	_	Number=Sing	_	_	_	_
25	Benn	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	M.A.	_	PROPN	_	Number=Sing	_	_	_	_
28	Martin	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	A.S.	_	PROPN	_	Number=Sing	_	_	_	_
32	Fauci	_	PROPN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	Science	_	PROPN	_	Number=Sing	_	_	_	_
35	231:600-602	_	NUM	_	NumType=Card	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	1986	_	NUM	_	NumType=Card	_	_	_	_
38	;	_	PUNCT	_	_	_	_	_	_
39	D.	_	PROPN	_	Number=Sing	_	_	_	_
40	Zagury	_	PROPN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	J.	_	PROPN	_	Number=Sing	_	_	_	_
43	Bernard	_	PROPN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	R.Leonard	_	PROPN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	R.Cheynier	_	PROPN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	M.Feldman	_	PROPN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	P.S.	_	PROPN	_	Number=Sing	_	_	_	_
52	Sarin	_	PROPN	_	Number=Sing	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	and	_	CCONJ	_	_	_	_	_	_
55	R.C.	_	PROPN	_	Number=Sing	_	_	_	_
56	Gallo	_	PROPN	_	Number=Sing	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	Science	_	PROPN	_	Number=Sing	_	_	_	_
59	231:850-853	_	NUM	_	NumType=Card	_	_	_	_
60	,	_	PUNCT	_	_	_	_	_	_
61	1986	_	NUM	_	NumType=Card	_	_	_	_
62	)	_	PUNCT	_	_	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	host	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	PROPN	_	Number=Sing	_	_	_	_
13	B	_	PROPN	_	Number=Sing	_	_	_	_
14	[	_	PUNCT	_	_	_	_	_	_
15	G.Nabel	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	D.	_	PROPN	_	Number=Sing	_	_	_	_
18	Baltimore	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	Nature	_	PROPN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	London	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	326:711-717	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	1987	_	NUM	_	NumType=Card	_	_	_	_
27	]	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	HIV	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1-	_	NUM	_	_	_	_	_	_
9	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	Nef	_	PROPN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	DNA	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	binding	_	VERB	_	Number=Sing	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_

1	Nef	_	PROPN	_	Number=Sing	_	_	_	_
2	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	other	_	ADJ	_	Degree=Pos	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	implicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	including	_	VERB	_	VerbForm=Ger	_	_	_	_
22	SP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	USF	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	URS	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	AT	_	PROPN	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_

1	Nef	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1-	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	effect	_	NOUN	_	Number=Sing	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	HIV	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	intact	_	ADJ	_	Degree=Pos	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	binding	_	NOUN	_	Number=Sing	_	_	_	_
35	site	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	defective	_	ADJ	_	Degree=Pos	_	_	_	_
6	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	underlie	_	VERB	_	VerbForm=Inf	_	_	_	_
14	Nef	_	PROPN	_	Number=Sing	_	_	_	_
15	's	_	PART	_	_	_	_	_	_
16	negative	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	effects	_	NOUN	_	Number=Plur	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	HIV	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	promoters	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	evidence	_	NOUN	_	Number=Sing	_	_	_	_
3	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Nef	_	PROPN	_	Number=Sing	_	_	_	_
6	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	interfering	_	VERB	_	VerbForm=Ger	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	signal	_	NOUN	_	Number=Sing	_	_	_	_
17	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	complex	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011543	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
9	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
10	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	kappa	_	VERB	_	Number=Sing	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	phosphatase	_	PROPN	_	Number=Sing	_	_	_	_
20	2A	_	NUM	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
23	sites	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	various	_	ADJ	_	Degree=Pos	_	_	_	_
9	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
11	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
16	degradation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	kappa	_	VERB	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	although	_	SCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	underlying	_	ADJ	_	Degree=Pos	_	_	_	_
29	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
30	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	serine	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	threonine	_	NOUN	_	Number=Sing	_	_	_	_
12	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	incubation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	low	_	ADJ	_	Degree=Pos	_	_	_	_
12	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	approximately	_	ADV	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	SYM	_	_	_	_	_	_
17	5	_	NUM	_	NumType=Card	_	_	_	_
18	nM	_	NOUN	_	Number=Plur	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	calyculin	_	NOUN	_	Number=Sing	_	_	_	_
22	A	_	NOUN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
25	acid	_	ADJ	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	potent	_	ADJ	_	Degree=Pos	_	_	_	_
28	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	protein	_	NOUN	_	Number=Sing	_	_	_	_
31	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
32	type	_	NOUN	_	Number=Sing	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	PP	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	SYM	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	type	_	NOUN	_	Number=Sing	_	_	_	_
41	2A	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	PP	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	SYM	_	_	_	_	_	_
45	2A	_	NOUN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
53	kappa	_	VERB	_	Number=Sing	_	_	_	_
54	B	_	PROPN	_	Number=Sing	_	_	_	_
55	alpha	_	NOUN	_	Number=Sing	_	_	_	_
56	even	_	ADV	_	_	_	_	_	_
57	in	_	ADP	_	_	_	_	_	_
58	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
59	absence	_	NOUN	_	Number=Sing	_	_	_	_
60	of	_	ADP	_	_	_	_	_	_
61	any	_	DET	_	_	_	_	_	_
62	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
63	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	action	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
6	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	RelA.p50	_	PROPN	_	Number=Sing	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	agents	_	NOUN	_	Number=Plur	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	block	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	induction	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
34	kappa	_	VERB	_	Number=Sing	_	_	_	_
35	B	_	PROPN	_	Number=Sing	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	tumor	_	NOUN	_	Number=Sing	_	_	_	_
40	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
41	factor	_	NOUN	_	Number=Sing	_	_	_	_
42	alpha	_	PROPN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	TNF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	alpha	_	NOUN	_	Number=Sing	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	phosphorylated	_	VERB	_	Number=Sing	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	kappa	_	VERB	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	calyculin	_	VERB	_	Number=Sing	_	_	_	_
11	A	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	TNF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	PP	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2A	_	PROPN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	vitro	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	existence	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	fundamental	_	ADJ	_	Degree=Pos	_	_	_	_
41	differences	_	NOUN	_	Number=Plur	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
47	kappa	_	VERB	_	Number=Sing	_	_	_	_
48	B	_	PROPN	_	Number=Sing	_	_	_	_
49	alpha	_	NOUN	_	Number=Sing	_	_	_	_
50	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	by	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	two	_	NUM	_	NumType=Card	_	_	_	_
54	different	_	ADJ	_	Degree=Pos	_	_	_	_
55	NF	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	kappa	_	NOUN	_	Number=Sing	_	_	_	_
58	B	_	NOUN	_	Number=Sing	_	_	_	_
59	inducers	_	NOUN	_	Number=Plur	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	kappa	_	VERB	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
18	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
24	degradation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
27	kappa	_	VERB	_	Number=Sing	_	_	_	_
28	B	_	PROPN	_	Number=Sing	_	_	_	_
29	alpha	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TNF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	calyculin	_	VERB	_	VerbForm=Inf	_	_	_	_
11	A	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	kappa	_	VERB	_	Number=Sing	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	degradation	_	NOUN	_	Number=Sing	_	_	_	_
19	exhibits	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	similar	_	ADJ	_	Degree=Pos	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	not	_	ADV	_	_	_	_	_	_
23	identical	_	ADJ	_	Degree=Pos	_	_	_	_
24	sensitivities	_	NOUN	_	Number=Plur	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
28	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	kappa	_	VERB	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	both	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	TNF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	inducible	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	PP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2A	_	NUM	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	opposing	_	VERB	_	VerbForm=Ger	_	_	_	_
30	kinases	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	may	_	AUX	_	VerbForm=Fin	_	_	_	_
33	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	target	_	VERB	_	VerbForm=Inf	_	_	_	_
36	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
37	kappa	_	VERB	_	Number=Sing	_	_	_	_
38	B	_	PROPN	_	Number=Sing	_	_	_	_
39	alpha	_	NOUN	_	Number=Sing	_	_	_	_
40	for	_	ADP	_	_	_	_	_	_
41	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	degradation	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011544	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	TNF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	release	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	protein	_	VERB	_	Number=Sing	_	_	_	_
18	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
19	kinase	_	NOUN	_	Number=Sing	_	_	_	_
20	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	protein	_	ADJ	_	Number=Sing	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	C	_	PROPN	_	Number=Sing	_	_	_	_
25	independent	_	ADJ	_	Degree=Pos	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
4	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	important	_	ADJ	_	Degree=Pos	_	_	_	_
15	mediator	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	septic	_	ADJ	_	Number=Sing	_	_	_	_
18	shock	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Endotoxin	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	LPS	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	signal	_	NOUN	_	Number=Sing	_	_	_	_
6	transduction	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	TNF	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	release	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	implicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	both	_	CCONJ	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	C	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	PKC	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	protein	_	VERB	_	Number=Sing	_	_	_	_
16	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
17	kinases	_	NOUN	_	Number=Plur	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	PTK	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	LPS	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	NF	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	TNF	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	alpha	_	NOUN	_	Number=Sing	_	_	_	_
33	production	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	hypothesized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	either	_	CCONJ	_	_	_	_	_	_
7	PKC	_	PROPN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	PTK	_	PROPN	_	Number=Sing	_	_	_	_
10	would	_	AUX	_	VerbForm=Fin	_	_	_	_
11	decrease	_	VERB	_	VerbForm=Inf	_	_	_	_
12	LPS	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	DNA	_	NOUN	_	Number=Sing	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	TNF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	release	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	MATERIALS	_	NOUN	_	Number=Plur	_	_	_	_
2	AND	_	CCONJ	_	_	_	_	_	_
3	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	PMA	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	50	_	NUM	_	NumType=Card	_	_	_	_
9	ng	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	ml	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	alone	_	ADJ	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	LPS	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	100	_	NUM	_	NumType=Card	_	_	_	_
18	ng	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	SYM	_	_	_	_	_	_
20	ml	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	without	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	nonspecific	_	ADJ	_	Degree=Pos	_	_	_	_
27	serine	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	threonine	_	NOUN	_	Number=Sing	_	_	_	_
30	protein	_	NOUN	_	Number=Sing	_	_	_	_
31	kinase	_	NOUN	_	Number=Sing	_	_	_	_
32	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
33	staurosporine	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	Stauro	_	PROPN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	specific	_	ADJ	_	Degree=Pos	_	_	_	_
40	pan-PKC	_	NOUN	_	Number=Sing	_	_	_	_
41	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
42	bisindolylmaleimide	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	Bis	_	PROPN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	or	_	CCONJ	_	_	_	_	_	_
48	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
49	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	PTK	_	PROPN	_	Number=Sing	_	_	_	_
52	genistein	_	NOUN	_	Number=Sing	_	_	_	_
53	(	_	PUNCT	_	_	_	_	_	_
54	Gen	_	PROPN	_	Number=Sing	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	release	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	culture	_	NOUN	_	Number=Sing	_	_	_	_
7	supernatants	_	NOUN	_	Number=Plur	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	ELISA	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	DNA	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
10	mobility	_	NOUN	_	Number=Sing	_	_	_	_
11	shift	_	NOUN	_	Number=Sing	_	_	_	_
12	assay	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	LPS	_	PROPN	_	Number=Sing	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	DNA	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	release	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Nonspecific	_	ADJ	_	Degree=Pos	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	kinase	_	NOUN	_	Number=Sing	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	release	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	while	_	SCONJ	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	PKC	_	PROPN	_	Number=Sing	_	_	_	_
19	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	Bis	_	PROPN	_	Number=Sing	_	_	_	_
22	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	no	_	DET	_	_	_	_	_	_
24	effect	_	NOUN	_	Number=Sing	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	LPS	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
32	DNA	_	NOUN	_	Number=Sing	_	_	_	_
33	binding	_	NOUN	_	Number=Sing	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	TNF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	release	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	PTK	_	NOUN	_	Number=Sing	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	Gen	_	PROPN	_	Number=Sing	_	_	_	_
5	attenuated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	LPS	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	TNF	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	production	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Direct	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	PKC	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	PMA	_	PROPN	_	Number=Sing	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	LPS	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	TNF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	release	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	independent	_	ADJ	_	Degree=Pos	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	PKC	_	PROPN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	evidence	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	PTK	_	PROPN	_	Number=Sing	_	_	_	_
9	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	LPS	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	TNF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	release	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	thus	_	ADV	_	_	_	_	_	_
30	could	_	AUX	_	VerbForm=Fin	_	_	_	_
31	be	_	AUX	_	VerbForm=Inf	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	potential	_	ADJ	_	Degree=Pos	_	_	_	_
34	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
35	target	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
38	states	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1999	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011545	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	characterization	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2-	_	NUM	_	_	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	critical	_	ADJ	_	Degree=Pos	_	_	_	_
11	early	_	ADJ	_	Degree=Pos	_	_	_	_
12	event	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	process	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Formation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	complex	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	essential	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	line	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	stably	_	ADV	_	_	_	_	_	_
8	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	trimer	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	element	_	NOUN	_	Number=Sing	_	_	_	_
19	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	lac	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	Z	_	PROPN	_	Number=Sing	_	_	_	_
25	reporter	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
29	screened	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1-	_	NUM	_	_	_	_	_	_
36	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
37	beta-galactosidase	_	NOUN	_	Number=Sing	_	_	_	_
38	activity	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	WIN	_	PROPN	_	Number=Sing	_	_	_	_
2	61058	_	NUM	_	NumType=Card	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	WIN	_	PROPN	_	Number=Sing	_	_	_	_
5	53071	_	NUM	_	NumType=Card	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	microM	_	ADJ	_	Degree=Pos	_	_	_	_
10	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	compounds	_	NOUN	_	Number=Plur	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	beta-galactosidase	_	NOUN	_	Number=Sing	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1-	_	NUM	_	_	_	_	_	_
7	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	line	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	stably	_	ADV	_	_	_	_	_	_
21	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	elements	_	NOUN	_	Number=Plur	_	_	_	_
28	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	reporter	_	NOUN	_	Number=Sing	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	for	_	ADP	_	_	_	_	_	_
34	sCD8	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	10	_	NUM	_	NumType=Card	_	_	_	_
3	microM	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	both	_	DET	_	_	_	_	_	_
6	compounds	_	NOUN	_	Number=Plur	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	lac	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	Z	_	NOUN	_	Number=Sing	_	_	_	_
25	transfectants	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	compounds	_	NOUN	_	Number=Plur	_	_	_	_
3	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	mixed	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
6	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
7	reaction	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	reversed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_
20	WIN	_	PROPN	_	Number=Sing	_	_	_	_
21	53071	_	NUM	_	NumType=Card	_	_	_	_
22	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	production	_	NOUN	_	Number=Sing	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	calcium	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
33	PMA	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	ionomycin	_	PROPN	_	Number=Sing	_	_	_	_
36	pathway	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Conversely	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	calcium	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	independent	_	ADJ	_	Degree=Pos	_	_	_	_
6	anti-CD28	_	NOUN	_	Number=Sing	_	_	_	_

1	Ab	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	PMA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	compounds	_	NOUN	_	Number=Plur	_	_	_	_
3	altered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	complex	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	causing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	retarded	_	ADJ	_	Degree=Pos	_	_	_	_
14	mobility	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	gels	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	functional	_	ADJ	_	Degree=Pos	_	_	_	_
4	criteria	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	believe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	two	_	NUM	_	NumType=Card	_	_	_	_
12	structurally	_	ADV	_	_	_	_	_	_
13	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	novel	_	NOUN	_	Number=Sing	_	_	_	_
16	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1-	_	NUM	_	_	_	_	_	_
21	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011546	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HIV	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	replication	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	combination	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	novel	_	NOUN	_	Number=Sing	_	_	_	_
12	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	AZT	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	small	_	ADJ	_	Degree=Pos	_	_	_	_
3	molecule	_	NOUN	_	Number=Sing	_	_	_	_
4	S9a	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	derived	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	tumor	_	NOUN	_	Number=Sing	_	_	_	_
11	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	Canventol	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	replacement	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	isopropylidine	_	NOUN	_	Number=Sing	_	_	_	_
29	group	_	NOUN	_	Number=Sing	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	phenyl	_	ADJ	_	Number=Sing	_	_	_	_
33	ring	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	S9a	_	PROPN	_	Number=Sing	_	_	_	_
2	at	_	ADP	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	100	_	NUM	_	NumType=Card	_	_	_	_
6	nM	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	as	_	ADV	_	_	_	_	_	_
11	potently	_	ADV	_	_	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	3'-	_	ADJ	_	NumType=Card	_	_	_	_
14	azido	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	3'-	_	NUM	_	NumType=Card	_	_	_	_
17	deoxythymidine	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	AZT	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	viral	_	ADJ	_	Degree=Pos	_	_	_	_
26	reverse	_	NOUN	_	Number=Sing	_	_	_	_
27	transcriptase	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	S9a	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	AZT	_	PROPN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	combination	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	noncytoxic	_	ADJ	_	Degree=Pos	_	_	_	_
11	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
12	strongly	_	ADV	_	_	_	_	_	_
13	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	HIV	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	replication	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	more	_	ADJ	_	Degree=Cmp	_	_	_	_
21	than	_	ADP	_	_	_	_	_	_
22	additive	_	ADJ	_	Degree=Pos	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	substantially	_	ADV	_	_	_	_	_	_
25	prolonged	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	appearance	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	virus	_	NOUN	_	Number=Sing	_	_	_	_
30	both	_	CCONJ	_	_	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	acutely	_	ADV	_	_	_	_	_	_
33	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	CD4	_	NOUN	_	Number=Sing	_	_	_	_
35	+	_	SYM	_	_	_	_	_	_
36	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	SupT	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	culture	_	NOUN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
45	blood	_	NOUN	_	Number=Sing	_	_	_	_
46	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	PBMCs	_	NOUN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
52	with	_	ADP	_	_	_	_	_	_
53	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
54	primary	_	ADJ	_	Degree=Pos	_	_	_	_
55	HIV	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	1	_	NUM	_	NumType=Card	_	_	_	_
58	isolate	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	S9a	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	TNF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	reporter	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	proposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	antiviral	_	ADJ	_	Degree=Pos	_	_	_	_
9	action	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	S9a	_	PROPN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	host	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	by	_	SCONJ	_	_	_	_	_	_
19	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
20	TNF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	via	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	Tat	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	tar	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	independent	_	ADJ	_	Degree=Pos	_	_	_	_
32	loop	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	which	_	PRON	_	PronType=Rel	_	_	_	_
35	decreases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	HIV	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	long	_	ADJ	_	Degree=Pos	_	_	_	_
46	terminal	_	NOUN	_	Number=Sing	_	_	_	_
47	repeat	_	NOUN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	LTR	_	PROPN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	S9a	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	superior	_	ADJ	_	Degree=Pos	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	generation	_	NOUN	_	Number=Sing	_	_	_	_
8	compound	_	NOUN	_	Number=Sing	_	_	_	_
9	Canventol	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	superior	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	natural	_	ADJ	_	Degree=Pos	_	_	_	_
17	compound	_	NOUN	_	Number=Sing	_	_	_	_
18	sarcophytol	_	NOUN	_	Number=Sing	_	_	_	_
19	A	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	further	_	ADJ	_	Degree=Pos	_	_	_	_
24	structure	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	potency	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
32	compounds	_	NOUN	_	Number=Plur	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	feasible	_	ADJ	_	Degree=Pos	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
6	approach	_	NOUN	_	Number=Sing	_	_	_	_
7	against	_	ADP	_	_	_	_	_	_
8	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	application	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	two	_	NUM	_	NumType=Card	_	_	_	_
13	drugs	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	one	_	NUM	_	NumType=Card	_	_	_	_
16	against	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	cellular	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	other	_	ADJ	_	Degree=Pos	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	viral	_	ADJ	_	Degree=Pos	_	_	_	_
24	target	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	which	_	PRON	_	PronType=Rel	_	_	_	_
27	may	_	AUX	_	VerbForm=Fin	_	_	_	_
28	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	approach	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	problem	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	frequent	_	ADJ	_	Degree=Pos	_	_	_	_
36	emergence	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
39	variants	_	NOUN	_	Number=Plur	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	combinations	_	NOUN	_	Number=Plur	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	drugs	_	NOUN	_	Number=Plur	_	_	_	_
44	that	_	PRON	_	PronType=Rel	_	_	_	_
45	target	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
46	only	_	ADV	_	_	_	_	_	_
47	HIV	_	ADJ	_	Degree=Pos	_	_	_	_
48	genes	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011547	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differentiation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	U	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	937	_	NUM	_	NumType=Card	_	_	_	_
6	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	etoposide	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	ICRF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	193	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	antitumour	_	ADJ	_	Degree=Pos	_	_	_	_
17	DNA	_	NOUN	_	Number=Sing	_	_	_	_
18	topoisomerase	_	NOUN	_	Number=Sing	_	_	_	_
19	II	_	NUM	_	NumType=Card	_	_	_	_
20	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	different	_	ADJ	_	Degree=Pos	_	_	_	_
23	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	action	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	action	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	U	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	937	_	NUM	_	NumType=Card	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	topoisomerase	_	NOUN	_	Number=Sing	_	_	_	_
18	II	_	NUM	_	NumType=Card	_	_	_	_
19	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	namely	_	VERB	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	epipodophyllotoxin	_	NOUN	_	Degree=Pos	_	_	_	_
24	etoposide	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	bisdioxopiperazine	_	NOUN	_	Number=Sing	_	_	_	_
28	ICRF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	193	_	NUM	_	NumType=Card	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	hour	_	NOUN	_	Number=Sing	_	_	_	_
3	pulse	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	treatment	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	3	_	NUM	_	NumType=Card	_	_	_	_
8	microM	_	NOUN	_	Degree=Pos	_	_	_	_
9	etoposide	_	NOUN	_	Number=Sing	_	_	_	_
10	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	topoisomerase	_	NOUN	_	Number=Sing	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	primary	_	ADJ	_	Degree=Pos	_	_	_	_
15	DNA	_	NOUN	_	Number=Sing	_	_	_	_
16	breakage	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	rapidly	_	ADV	_	_	_	_	_	_
21	followed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	upon	_	ADP	_	_	_	_	_	_
10	pulse	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	treatment	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	6	_	NUM	_	NumType=Card	_	_	_	_
15	microM	_	NOUN	_	Number=Sing	_	_	_	_
16	ICRF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	193	_	NUM	_	NumType=Card	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	continuous	_	ADJ	_	Degree=Pos	_	_	_	_
4	treatments	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	subcytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
7	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	etoposide	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	0.15	_	NUM	_	NumType=Card	_	_	_	_
12	microM	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	ICRF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	193	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	0.3	_	NUM	_	NumType=Card	_	_	_	_
20	microM	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	several	_	ADJ	_	Degree=Pos	_	_	_	_
24	similar	_	ADJ	_	Degree=Pos	_	_	_	_
25	effects	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	namely	_	ADV	_	_	_	_	_	_
28	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	at	_	ADP	_	_	_	_	_	_
36	G2	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	increase	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	mass	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	induction	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Under	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	conditions	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	etoposide	_	NOUN	_	Number=Sing	_	_	_	_
6	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	C	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	consisted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	early	_	ADJ	_	Degree=Pos	_	_	_	_
20	transient	_	ADJ	_	Degree=Pos	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	hours	_	NOUN	_	Number=Plur	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	6	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	membrane	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	bound	_	ADJ	_	Degree=Pos	_	_	_	_
34	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
35	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	later	_	ADJ	_	Degree=Cmp	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	hour	_	NOUN	_	Number=Sing	_	_	_	_
42	48	_	NUM	_	NumType=Card	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	total	_	ADJ	_	Degree=Pos	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	membrane	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	bound	_	ADJ	_	Degree=Pos	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
53	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	ICRF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	193	_	NUM	_	NumType=Card	_	_	_	_
7	only	_	ADV	_	_	_	_	_	_
8	provoked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	late	_	ADJ	_	Degree=Pos	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	hours	_	NOUN	_	Number=Plur	_	_	_	_
15	72	_	NUM	_	NumType=Card	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	96	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	total	_	ADJ	_	Degree=Pos	_	_	_	_
22	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	at	_	ADP	_	_	_	_	_	_
4	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	topoisomerase	_	ADJ	_	Number=Sing	_	_	_	_
11	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
12	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	great	_	ADJ	_	Degree=Pos	_	_	_	_
15	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	AP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	maximum	_	ADJ	_	Degree=Pos	_	_	_	_
25	value	_	NOUN	_	Number=Sing	_	_	_	_
26	at	_	ADP	_	_	_	_	_	_
27	hour	_	NOUN	_	Number=Sing	_	_	_	_
28	12	_	NUM	_	NumType=Card	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	etoposide	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	at	_	ADP	_	_	_	_	_	_
36	hour	_	NOUN	_	Number=Sing	_	_	_	_
37	48	_	NUM	_	NumType=Card	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	ICRF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	193	_	NUM	_	NumType=Card	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	EGR	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factors	_	NOUN	_	Number=Plur	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	little	_	ADV	_	Degree=Pos	_	_	_	_
23	affected	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	concluded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	topoisomerase	_	NOUN	_	Number=Sing	_	_	_	_
6	II	_	NUM	_	NumType=Card	_	_	_	_
7	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	independently	_	ADV	_	_	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	capacity	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	cause	_	VERB	_	VerbForm=Inf	_	_	_	_
22	DNA	_	PROPN	_	Number=Sing	_	_	_	_
23	strand	_	NOUN	_	Number=Sing	_	_	_	_
24	breaks	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	there	_	PRON	_	_	_	_	_	_
4	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	other	_	ADJ	_	Degree=Pos	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	such	_	ADJ	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	early	_	ADJ	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	C	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	probably	_	ADV	_	_	_	_	_	_
21	derived	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	production	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	primary	_	ADJ	_	Degree=Pos	_	_	_	_
27	DNA	_	NOUN	_	Number=Sing	_	_	_	_
28	breakage	_	NOUN	_	Number=Sing	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	some	_	DET	_	_	_	_	_	_
31	anti-topoisomerase	_	ADJ	_	Number=Sing	_	_	_	_
32	drugs	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011549	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Oct2	_	PROPN	_	Number=Sing	_	_	_	_
2	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	remote	_	ADJ	_	Degree=Pos	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	position	_	NOUN	_	Number=Sing	_	_	_	_
8	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	B	_	NUM	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	Oct2	_	PROPN	_	Number=Sing	_	_	_	_
17	could	_	AUX	_	VerbForm=Fin	_	_	_	_
18	efficiently	_	ADV	_	_	_	_	_	_
19	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	octamer	_	NOUN	_	Number=Sing	_	_	_	_
25	motif	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Oct2	_	PROPN	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	unable	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	multimerized	_	ADJ	_	Degree=Pos	_	_	_	_
9	octamer	_	NOUN	_	Number=Sing	_	_	_	_
10	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
11	element	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	however	_	ADV	_	_	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	variety	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Oct2	_	PROPN	_	Degree=Pos	_	_	_	_
8	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
9	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
12	splicing	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	capability	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	octamer	_	NOUN	_	Number=Sing	_	_	_	_
20	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	nonlymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	line	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	analyses	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	several	_	ADJ	_	Degree=Pos	_	_	_	_
6	Oct2	_	PROPN	_	Degree=Pos	_	_	_	_
7	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	remote	_	ADJ	_	Degree=Pos	_	_	_	_
13	position	_	NOUN	_	Number=Sing	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	B	_	ADJ	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	result	_	NOUN	_	Number=Sing	_	_	_	_
3	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	involvement	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	either	_	CCONJ	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	B	_	NUM	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	cofactor	_	NOUN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	modification	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	cofactor	_	NOUN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	Oct2	_	PROPN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	Oct2	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Mutational	_	ADJ	_	Degree=Pos	_	_	_	_
2	analyses	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	carboxy	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	terminal	_	NOUN	_	Number=Sing	_	_	_	_
9	domain	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Oct2	_	PROPN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	critical	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	domain	_	NOUN	_	Number=Sing	_	_	_	_
5	conferred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	enhancing	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	when	_	ADV	_	PronType=Int	_	_	_	_
9	fused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	Oct1	_	PROPN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	itself	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs|Reflex=Yes	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	unable	_	ADJ	_	Degree=Pos	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	remote	_	ADJ	_	Degree=Pos	_	_	_	_
25	position	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	glutamine	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	rich	_	ADJ	_	Degree=Pos	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	domain	_	NOUN	_	Number=Sing	_	_	_	_
7	present	_	VERB	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	amino	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
13	portion	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	Oct2	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	POU	_	PROPN	_	Number=Sing	_	_	_	_
19	domain	_	NOUN	_	Number=Sing	_	_	_	_
20	contribute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	only	_	ADV	_	_	_	_	_	_
22	marginally	_	ADV	_	_	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
26	function	_	NOUN	_	Number=Sing	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	distal	_	ADJ	_	Degree=Pos	_	_	_	_
30	position	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011551	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Effect	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	adenovirus	_	NOUN	_	Number=Sing	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	blood	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	adenovirus	_	NOUN	_	Number=Sing	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	Ad2	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	infection	_	NOUN	_	Number=Sing	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	regard	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	TNF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alpha	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	beta	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	bound	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	surface	_	NOUN	_	Number=Sing	_	_	_	_
11	without	_	SCONJ	_	_	_	_	_	_
12	being	_	AUX	_	VerbForm=Ger	_	_	_	_
13	internalized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	hand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	Ad2	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	internalized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	virus	_	NOUN	_	Number=Sing	_	_	_	_
3	replication	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	no	_	DET	_	_	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Ad2	_	NOUN	_	Number=Sing	_	_	_	_
10	early	_	ADJ	_	Degree=Pos	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	either	_	DET	_	_	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Ad2	_	NOUN	_	Number=Sing	_	_	_	_
2	infection	_	NOUN	_	Number=Sing	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	transient	_	ADJ	_	Degree=Pos	_	_	_	_
5	increase	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	beta	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	although	_	SCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
33	slightly	_	ADV	_	_	_	_	_	_
34	different	_	ADJ	_	Degree=Pos	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	production	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	both	_	DET	_	_	_	_	_	_
5	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	ELISA	_	PROPN	_	Number=Sing	_	_	_	_
10	tests	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	slight	_	ADJ	_	Degree=Pos	_	_	_	_
6	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	whereas	_	SCONJ	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	might	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	Ad2	_	PROPN	_	Number=Sing	_	_	_	_
12	virus	_	NOUN	_	Number=Sing	_	_	_	_
13	infection	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	nonpermissive	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	where	_	ADV	_	PronType=Rel	_	_	_	_
18	no	_	DET	_	_	_	_	_	_
19	viral	_	ADJ	_	Degree=Pos	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	products	_	NOUN	_	Number=Plur	_	_	_	_
22	could	_	AUX	_	VerbForm=Fin	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011552	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	early	_	ADJ	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	adherent	_	ADJ	_	Degree=Pos	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	kappa	_	VERB	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	like	_	ADP	_	Degree=Pos	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	group	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cDNAs	_	NOUN	_	Number=Plur	_	_	_	_
8	representing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	rapidly	_	ADV	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	following	_	VERB	_	VerbForm=Ger	_	_	_	_
15	adherence	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	MAD	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	3	_	X	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	317	_	NUM	_	NumType=Card	_	_	_	_
16	amino	_	NOUN	_	Number=Sing	_	_	_	_
17	acids	_	NOUN	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	one	_	NUM	_	NumType=Card	_	_	_	_
20	domain	_	NOUN	_	Number=Sing	_	_	_	_
21	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	five	_	NUM	_	NumType=Card	_	_	_	_
23	tandem	_	NOUN	_	Number=Sing	_	_	_	_
24	repeats	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	cdc10	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	ankyrin	_	NOUN	_	Number=Sing	_	_	_	_
30	motif	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	60	_	NUM	_	NumType=Card	_	_	_	_
35	%	_	SYM	_	Number=Sing	_	_	_	_
36	similar	_	ADJ	_	Degree=Pos	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	46	_	NUM	_	NumType=Card	_	_	_	_
39	%	_	SYM	_	Number=Sing	_	_	_	_
40	identical	_	ADJ	_	Degree=Pos	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	to	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	ankyrin	_	ADJ	_	Number=Sing	_	_	_	_
45	repeat	_	ADJ	_	Number=Sing	_	_	_	_
46	region	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	precursor	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	NF	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	kappa	_	NOUN	_	Number=Sing	_	_	_	_
54	B	_	NOUN	_	Number=Sing	_	_	_	_
55	/	_	PUNCT	_	_	_	_	_	_
56	KBF1	_	PROPN	_	Number=Sing	_	_	_	_
57	p50	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	C-terminus	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	putative	_	ADJ	_	Degree=Pos	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	C	_	PROPN	_	Number=Sing	_	_	_	_
9	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	MAD	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	3	_	NUM	_	NumType=Card	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	specifically	_	ADV	_	_	_	_	_	_
12	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	DNA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	complex	_	NOUN	_	Number=Sing	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	not	_	ADV	_	_	_	_	_	_
28	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	p50/p50	_	NUM	_	NumType=Card	_	_	_	_
32	KBF1	_	NOUN	_	Number=Sing	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	other	_	ADJ	_	Degree=Pos	_	_	_	_
37	DNA	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	binding	_	VERB	_	Number=Sing	_	_	_	_
40	proteins	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	MAD	_	NOUN	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	3	_	NUM	_	NumType=Card	_	_	_	_
5	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
6	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	kappa	_	VERB	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	like	_	ADP	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	likely	_	ADV	_	_	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	involved	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	regulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
24	responses	_	NOUN	_	Number=Plur	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	including	_	VERB	_	VerbForm=Ger	_	_	_	_
32	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
35	pathways	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
38	activation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011556	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
11	lines	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	anetholdithiolthione	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	redox	_	ADJ	_	Number=Sing	_	_	_	_
5	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
6	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Redox	_	NOUN	_	Number=Sing	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	PROPN	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	immuno	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
20	virus	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	effective	_	ADJ	_	Degree=Pos	_	_	_	_
14	strategy	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	acquired	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
18	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
19	therapy	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Anetholdithiolthione	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	ADT	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	5-[p-methoxyphenyl]-3H-1,2-dithiol-3-thione	_	NUM	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	protect	_	VERB	_	VerbForm=Inf	_	_	_	_
16	against	_	ADP	_	_	_	_	_	_
17	acetaminophen	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	CCl4	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	hepatotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	lipid	_	ADJ	_	Degree=Pos	_	_	_	_
26	peroxidation	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	radiation	_	NOUN	_	Number=Sing	_	_	_	_
29	injury	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	also	_	ADV	_	_	_	_	_	_
33	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
35	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	clinically	_	ADV	_	_	_	_	_	_
37	as	_	ADP	_	_	_	_	_	_
38	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	anti-choleretic	_	ADJ	_	Degree=Pos	_	_	_	_
40	agent	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	ADT	_	NOUN	_	Number=Sing	_	_	_	_
9	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	variety	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
23	such	_	ADJ	_	Degree=Pos	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
28	myristate	_	NOUN	_	Number=Sing	_	_	_	_
29	acetate	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	PMA	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	tumor	_	NOUN	_	Number=Sing	_	_	_	_
35	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
36	factor	_	NOUN	_	Number=Sing	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	TNF	_	PROPN	_	Number=Sing	_	_	_	_
40	alpha	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	PMA	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	TNF	_	PROPN	_	Number=Sing	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
17	T-cells	_	PROPN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	partially	_	ADV	_	_	_	_	_	_
20	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	ADT	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	0.1	_	NUM	_	NumType=Card	_	_	_	_
25	mM	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	ADT	_	NOUN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	0.1	_	NUM	_	NumType=Card	_	_	_	_
4	mM	_	NOUN	_	NumType=Card	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	H2O2	_	PROPN	_	Number=Sing	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	peroxide	_	NOUN	_	Degree=Pos	_	_	_	_
18	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	Wurzburg	_	NOUN	_	Number=Sing	_	_	_	_
21	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	ADT	_	PROPN	_	Number=Sing	_	_	_	_
4	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	Wurzburg	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	significantly	_	ADV	_	_	_	_	_	_
9	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
10	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	as	_	SCONJ	_	_	_	_	_	_
13	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
2	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	lipid	_	ADJ	_	Degree=Pos	_	_	_	_
4	peroxidation	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	Wurzburg	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	remarkably	_	ADV	_	_	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	ADT	_	NOUN	_	Number=Sing	_	_	_	_
13	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	ADT	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	pro-glutathione	_	ADJ	_	Degree=Pos	_	_	_	_
5	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	capable	_	ADJ	_	Degree=Pos	_	_	_	_
12	of	_	SCONJ	_	_	_	_	_	_
13	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011564	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Thrombopoietin	_	PROPN	_	Number=Sing	_	_	_	_
2	supports	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vitro	_	NOUN	_	Number=Sing	_	_	_	_
5	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
6	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
7	via	_	ADP	_	_	_	_	_	_
8	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	c-Mpl	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	line	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Thrombopoietin	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	TPO	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	acts	_	VERB	_	Number=Plur	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	megakaryopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	erythropoiesis	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	vitro	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vivo	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	isolated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	subline	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	UT	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	7/GMT	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	line	_	NOUN	_	Number=Sing	_	_	_	_
17	UT	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	7/GM	_	PROPN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	N.	_	PROPN	_	Number=Sing	_	_	_	_
22	Komatsu	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	et	_	X	_	_	_	_	_	_
25	al	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	Blood	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	89	_	NUM	_	NumType=Card	_	_	_	_
31	:	_	PUNCT	_	_	_	_	_	_
32	4021-4033	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	1997	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	small	_	ADJ	_	Degree=Pos	_	_	_	_
3	population	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	UT	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	7/GM	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	positively	_	ADV	_	_	_	_	_	_
10	stained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	hemoglobin	_	PROPN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	Hb	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	after	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	7	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	day	_	NOUN	_	Number=Sing	_	_	_	_
21	exposure	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	TPO	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	More	_	ADJ	_	Degree=Cmp	_	_	_	_
2	than	_	ADP	_	_	_	_	_	_
3	50	_	NUM	_	NumType=Card	_	_	_	_
4	%	_	SYM	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	TPO	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	UT	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	7/GMT	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	positively	_	ADV	_	_	_	_	_	_
14	stained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	Hb	_	PROPN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	UT	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	7/GMT	_	PROPN	_	NumType=Card	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	how	_	ADV	_	PronType=Int	_	_	_	_
10	TPO	_	PROPN	_	Number=Sing	_	_	_	_
11	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	hemoglobinization	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	TPO	_	PROPN	_	Number=Sing	_	_	_	_
2	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	TPO	_	NOUN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	EPO	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	competition	_	NOUN	_	Number=Sing	_	_	_	_
5	between	_	ADP	_	_	_	_	_	_
6	TPO	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	EPO	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	SCONJ	_	_	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	EPO	_	NOUN	_	Number=Sing	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TPO	_	PROPN	_	Number=Sing	_	_	_	_
6	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	direct	_	ADJ	_	Degree=Pos	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	hemoglobinization	_	NOUN	_	Number=Sing	_	_	_	_
12	via	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	UT	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	7/GMT	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Isoelectric	_	ADJ	_	Number=Sing	_	_	_	_
2	focusing	_	NOUN	_	VerbForm=Ger	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TPO	_	PROPN	_	Number=Sing	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	fetal	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	adult	_	NOUN	_	Number=Sing	_	_	_	_
10	Hb	_	NOUN	_	Number=Sing	_	_	_	_
11	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	whereas	_	SCONJ	_	_	_	_	_	_
14	EPO	_	NOUN	_	Number=Sing	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	embryonic	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	fetal	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	adult	_	NOUN	_	Number=Sing	_	_	_	_
22	Hb	_	PROPN	_	Number=Sing	_	_	_	_
23	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	TPO	_	PROPN	_	Number=Sing	_	_	_	_
8	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
11	action	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	erythropoiesis	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011566	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
4	sites	_	NOUN	_	Number=Plur	_	_	_	_
5	downstream	_	ADV	_	Degree=Pos	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	type	_	NOUN	_	Number=Sing	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	start	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	important	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	virus	_	NOUN	_	Number=Sing	_	_	_	_
20	infectivity	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	transcriptionally	_	ADV	_	_	_	_	_	_
3	active	_	ADJ	_	Degree=Pos	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	nucleosome	_	NOUN	_	Degree=Pos	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	free	_	ADJ	_	Degree=Pos	_	_	_	_
18	region	_	NOUN	_	Number=Sing	_	_	_	_
19	encompassing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
25	region	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	large	_	ADJ	_	Degree=Pos	_	_	_	_
29	region	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	255	_	NUM	_	NumType=Card	_	_	_	_
32	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
33	[	_	PUNCT	_	_	_	_	_	_
34	nt	_	X	_	_	_	_	_	_
35	]	_	PUNCT	_	_	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	downstream	_	ADV	_	Degree=Pos	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	transcription	_	NOUN	_	Number=Sing	_	_	_	_
41	start	_	NOUN	_	Number=Sing	_	_	_	_
42	site	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	new	_	ADJ	_	Degree=Pos	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	downstream	_	ADV	_	Degree=Pos	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	start	_	NOUN	_	Number=Sing	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	nt	_	SYM	_	_	_	_	_	_
19	465	_	NUM	_	NumType=Card	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	720	_	NUM	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	:	_	PUNCT	_	_	_	_	_	_
24	three	_	NUM	_	NumType=Card	_	_	_	_
25	AP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	sites	_	NOUN	_	Number=Plur	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	II	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	III	_	PROPN	_	NumType=Card	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	AP3	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	like	_	ADJ	_	Degree=Pos	_	_	_	_
42	motif	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	AP3	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	L	_	NOUN	_	Number=Sing	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
50	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
51	binding	_	NOUN	_	Number=Sing	_	_	_	_
52	factor	_	NOUN	_	Number=Sing	_	_	_	_
53	(	_	PUNCT	_	_	_	_	_	_
54	DBF	_	NOUN	_	Number=Sing	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	site	_	NOUN	_	Number=Sing	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	and	_	CCONJ	_	_	_	_	_	_
59	juxtaposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
60	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
61	sites	_	NOUN	_	Number=Plur	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	DBF	_	PROPN	_	Number=Sing	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	interferon	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	IRF	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	binding	_	VERB	_	Number=Sing	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	AP3	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	L	_	PROPN	_	Number=Sing	_	_	_	_
26	motif	_	NOUN	_	Number=Sing	_	_	_	_
27	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	specific	_	ADJ	_	Degree=Pos	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	AT	_	NOUN	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	that	_	PRON	_	PronType=Rel	_	_	_	_
3	abolish	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	each	_	DET	_	_	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	cognate	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	introduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	infectious	_	ADJ	_	Degree=Pos	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
22	clone	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	study	_	VERB	_	VerbForm=Inf	_	_	_	_
25	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	effect	_	NOUN	_	Number=Sing	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	HIV	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	replication	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Individual	_	ADJ	_	Degree=Pos	_	_	_	_
2	mutation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	DBF	_	PROPN	_	Number=Sing	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	AP3-L	_	NOUN	_	Number=Sing	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	as	_	ADV	_	_	_	_	_	_
10	well	_	ADV	_	Degree=Pos	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	double	_	ADJ	_	Degree=Pos	_	_	_	_
14	mutation	_	NOUN	_	Number=Sing	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	III	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	AP3-L	_	NOUN	_	Number=Sing	_	_	_	_
23	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
26	HIV	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	replication	_	NOUN	_	Number=Sing	_	_	_	_
30	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	wild	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	type	_	NOUN	_	Number=Sing	_	_	_	_
38	virus	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	proviruses	_	NOUN	_	Number=Plur	_	_	_	_
5	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
6	mutations	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
10	sites	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	totally	_	ADV	_	_	_	_	_	_
13	defective	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	terms	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	replication	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Virus	_	NOUN	_	Number=Sing	_	_	_	_
2	production	_	NOUN	_	Number=Sing	_	_	_	_
3	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	slightly	_	ADV	_	_	_	_	_	_
6	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
7	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	viruses	_	NOUN	_	Number=Plur	_	_	_	_
10	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	mutations	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	III	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	AP3	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	L	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	DBF	_	NOUN	_	Number=Sing	_	_	_	_
28	sites	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	AP3-L	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	DBF	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	sites	_	NOUN	_	Number=Plur	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	whereas	_	SCONJ	_	_	_	_	_	_
39	viruses	_	NOUN	_	Number=Plur	_	_	_	_
40	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	AP	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	I,II	_	NUM	_	NumType=Card	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	III	_	X	_	NumType=Card	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	AP3	_	NOUN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	L	_	NOUN	_	Number=Sing	_	_	_	_
55	sites	_	NOUN	_	Number=Plur	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	in	_	ADP	_	_	_	_	_	_
58	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
59	AP	_	NOUN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	1	_	NUM	_	NumType=Card	_	_	_	_
62	(	_	PUNCT	_	_	_	_	_	_
63	I,II	_	NUM	_	NumType=Card	_	_	_	_
64	,	_	PUNCT	_	_	_	_	_	_
65	III	_	NUM	_	NumType=Card	_	_	_	_
66	)	_	PUNCT	_	_	_	_	_	_
67	,	_	PUNCT	_	_	_	_	_	_
68	AP3	_	NOUN	_	Number=Sing	_	_	_	_
69	-	_	PUNCT	_	_	_	_	_	_
70	L	_	NOUN	_	Number=Sing	_	_	_	_
71	,	_	PUNCT	_	_	_	_	_	_
72	and	_	CCONJ	_	_	_	_	_	_
73	DBF	_	NOUN	_	Number=Sing	_	_	_	_
74	sites	_	NOUN	_	Number=Plur	_	_	_	_
75	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
76	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
77	severely	_	ADV	_	_	_	_	_	_
78	defective	_	ADJ	_	Degree=Pos	_	_	_	_
79	replicative	_	ADJ	_	Degree=Pos	_	_	_	_
80	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
81	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	RNA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	packaging	_	NOUN	_	Number=Sing	_	_	_	_
5	defect	_	NOUN	_	Number=Sing	_	_	_	_
6	could	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	any	_	DET	_	_	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	mutant	_	ADJ	_	Number=Sing	_	_	_	_
14	viruses	_	NOUN	_	Number=Plur	_	_	_	_
15	as	_	SCONJ	_	_	_	_	_	_
16	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	quantification	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	HIV	_	ADJ	_	Number=Sing	_	_	_	_
22	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
23	RNA	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Measurement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	HIV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	transient	_	ADJ	_	Degree=Pos	_	_	_	_
14	transfection	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	HIV	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	provirus	_	ADJ	_	Number=Sing	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	long	_	ADJ	_	Degree=Pos	_	_	_	_
25	terminal	_	NOUN	_	Number=Sing	_	_	_	_
26	repeat	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
29	constructs	_	NOUN	_	Number=Plur	_	_	_	_
30	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	positive	_	ADJ	_	Degree=Pos	_	_	_	_
33	correlation	_	NOUN	_	Number=Sing	_	_	_	_
34	between	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	transcriptional	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	replication	_	NOUN	_	Number=Sing	_	_	_	_
40	defects	_	NOUN	_	Number=Plur	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	most	_	ADJ	_	Degree=Sup	_	_	_	_
43	mutants	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011567	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	High	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	level	_	NOUN	_	Number=Sing	_	_	_	_
4	replication	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	interaction	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
20	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
6	interaction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	autologous	_	ADJ	_	Degree=Pos	_	_	_	_
12	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
13	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	TEC	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	prerequisite	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	high	_	ADJ	_	Degree=Pos	_	_	_	_
24	level	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
28	virus	_	NOUN	_	Number=Sing	_	_	_	_
29	type	_	NOUN	_	Number=Sing	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	HIV	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	replication	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	thymocytes	_	PROPN	_	Number=Plur	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	M.	_	PROPN	_	Number=Sing	_	_	_	_
41	Rothe	_	PROPN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	L.	_	PROPN	_	Number=Sing	_	_	_	_
44	Chene	_	PROPN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	M.Nugeyre	_	PROPN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	F.Barre	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	Sinoussi	_	PROPN	_	Number=Sing	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	N.Israel	_	PROPN	_	Number=Sing	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	J.Virol.72:5852-5861	_	PROPN	_	Number=Sing	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	1998	_	NUM	_	NumType=Card	_	_	_	_
58	)	_	PUNCT	_	_	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	replication	_	NOUN	_	Number=Sing	_	_	_	_
10	takes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	place	_	NOUN	_	Number=Sing	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	Rel	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	factors	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	first	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	provirus	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	SF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	strain	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	very	_	ADV	_	_	_	_	_	_
17	effectively	_	ADV	_	_	_	_	_	_
18	replicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	thymocytes	_	NOUN	_	Number=Sing	_	_	_	_
21	cocultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	TEC	_	PROPN	_	Number=Sing	_	_	_	_
24	whereas	_	SCONJ	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	provirus	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
30	sites	_	NOUN	_	Number=Plur	_	_	_	_
31	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	fails	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	evidence	_	NOUN	_	Number=Sing	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	several	_	ADJ	_	Degree=Pos	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	complexes	_	NOUN	_	Number=Plur	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	constitutively	_	ADV	_	_	_	_	_	_
12	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	either	_	CCONJ	_	_	_	_	_	_
19	freshly	_	ADV	_	_	_	_	_	_
20	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	thymus	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	maintained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	coculture	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	autologous	_	NOUN	_	Number=Sing	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
32	TEC	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	prevalent	_	ADJ	_	Degree=Pos	_	_	_	_
3	complex	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
7	p50-p65	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	tightly	_	ADV	_	_	_	_	_	_
7	correlated	_	ADJ	_	Degree=Pos	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	long	_	ADJ	_	Degree=Pos	_	_	_	_
15	terminal	_	NOUN	_	Number=Sing	_	_	_	_
16	repeat	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	LTR	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	HIV	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	LTR	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	mutated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
9	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
10	molecule	_	NOUN	_	Number=Sing	_	_	_	_
11	formally	_	ADV	_	_	_	_	_	_
12	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	LTR	_	PROPN	_	Number=Sing	_	_	_	_
15	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	members	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	Rel	_	PROPN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	family	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	DET	_	_	_	_	_	_
5	tumor	_	NOUN	_	Number=Sing	_	_	_	_
6	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	TNF	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	lesser	_	ADJ	_	Degree=Cmp	_	_	_	_
15	extent	_	NOUN	_	Number=Sing	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	within	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	coculture	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	activity	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	correlative	_	ADJ	_	Degree=Pos	_	_	_	_
38	LTR	_	NOUN	_	Number=Sing	_	_	_	_
39	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	7	_	NUM	_	NumType=Card	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	thymopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	secreted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	mainly	_	ADV	_	_	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	TEC	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
21	cofactor	_	NOUN	_	Number=Sing	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	elicited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	TNF	_	PROPN	_	Number=Sing	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	high	_	ADJ	_	Degree=Pos	_	_	_	_
16	level	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	replication	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	manner	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
32	microenvironment	_	NOUN	_	Number=Sing	_	_	_	_
33	which	_	PRON	_	PronType=Rel	_	_	_	_
34	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
37	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
38	:	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	7.	_	NUM	_	NumType=Card	_	_	_	_
11	Document	_	NOUN	_	Number=Sing	_	_	_	_
12	0030011571	_	NUM	_	NumType=Card	_	_	_	_
13	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
7	lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	toll	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	like	_	ADJ	_	Degree=Pos	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Apoptosis	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	generation	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	resolution	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
15	pathogens	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
3	pathogens	_	NOUN	_	Number=Plur	_	_	_	_
4	produce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	BLPs	_	NOUN	_	Number=Plur	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	trigger	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	innate	_	ADJ	_	Degree=Pos	_	_	_	_
14	immune	_	ADJ	_	Degree=Pos	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	BLPs	_	NOUN	_	Number=Plur	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
6	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	THP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	through	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	Toll	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	like	_	ADP	_	Degree=Pos	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	hTLR2	_	NOUN	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	BLPs	_	NOUN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	line	_	NOUN	_	Number=Sing	_	_	_	_
10	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	hTLR2	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	BLPs	_	NOUN	_	Number=Sing	_	_	_	_
5	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
13	activator	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
16	host	_	NOUN	_	Number=Sing	_	_	_	_
17	defense	_	NOUN	_	Number=Sing	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	respiratory	_	NOUN	_	Number=Sing	_	_	_	_
24	burst	_	NOUN	_	Number=Sing	_	_	_	_
25	through	_	ADP	_	_	_	_	_	_
26	hTLR2	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	hTLR2	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
7	link	_	NOUN	_	Number=Sing	_	_	_	_
8	between	_	ADP	_	_	_	_	_	_
9	microbial	_	ADJ	_	Degree=Pos	_	_	_	_
10	products	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	host	_	VERB	_	Number=Sing	_	_	_	_
16	defense	_	NOUN	_	Number=Sing	_	_	_	_
17	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011579	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	like	_	ADP	_	Degree=Pos	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	preferentially	_	ADV	_	_	_	_	_	_
14	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	6	_	NUM	_	NumType=Card	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	related	_	ADJ	_	Degree=Pos	_	_	_	_
23	motifs	_	NOUN	_	Number=Plur	_	_	_	_
24	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
25	activities	_	NOUN	_	Number=Plur	_	_	_	_
26	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	repressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	proto	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
5	c	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Rel	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	member	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	family	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	p50	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	p65	_	NUM	_	Number=Sing	_	_	_	_
27	subunits	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
6	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	kappa	_	VERB	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	sites	_	NOUN	_	Number=Plur	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
13	as	_	ADV	_	_	_	_	_	_
14	well	_	ADV	_	Degree=Pos	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	p50	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
7	DNA	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	specificities	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	affinities	_	NOUN	_	Number=Plur	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	various	_	ADJ	_	Degree=Pos	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	motifs	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	particular	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	c	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Rel	_	NOUN	_	Number=Sing	_	_	_	_
8	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
9	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	high	_	ADJ	_	Degree=Pos	_	_	_	_
12	affinity	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	6	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	6	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	beta	_	NOUN	_	Number=Sing	_	_	_	_
24	interferon	_	NOUN	_	Number=Sing	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	sites	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	spite	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
5	association	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	p50	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	vitro	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	however	_	ADV	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	vivo	_	NOUN	_	Number=Sing	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	not	_	ADV	_	_	_	_	_	_
29	p50	_	NUM	_	Number=Sing	_	_	_	_
30	epitopes	_	NOUN	_	Number=Plur	_	_	_	_
31	;	_	PUNCT	_	_	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	6	_	NUM	_	NumType=Card	_	_	_	_
39	kappa	_	NOUN	_	Number=Sing	_	_	_	_
40	B	_	NOUN	_	Number=Sing	_	_	_	_
41	binding	_	NOUN	_	Number=Sing	_	_	_	_
42	factor	_	NOUN	_	Number=Sing	_	_	_	_
43	II	_	NUM	_	NumType=Card	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
46	to	_	PART	_	_	_	_	_	_
47	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
50	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	preferentially	_	ADV	_	_	_	_	_	_
53	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
54	several	_	ADJ	_	Degree=Pos	_	_	_	_
55	IL	_	PROPN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	6	_	NUM	_	NumType=Card	_	_	_	_
58	kappa	_	NOUN	_	Number=Sing	_	_	_	_
59	B	_	NOUN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	related	_	ADJ	_	Degree=Pos	_	_	_	_
62	kappa	_	NOUN	_	Number=Sing	_	_	_	_
63	B	_	NOUN	_	Number=Sing	_	_	_	_
64	motifs	_	NOUN	_	Number=Plur	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	previously	_	ADV	_	_	_	_	_	_
6	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	6	_	NUM	_	NumType=Card	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	motif	_	NOUN	_	Number=Sing	_	_	_	_
15	functions	_	NOUN	_	Number=Plur	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	potent	_	ADJ	_	Degree=Pos	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1/tumor	_	NOUN	_	Number=Sing	_	_	_	_
22	necrosis	_	ADJ	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
26	element	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	nonlymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
32	activity	_	NOUN	_	Number=Sing	_	_	_	_
33	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
34	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	be	_	AUX	_	VerbForm=Inf	_	_	_	_
37	repressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	such	_	ADJ	_	Degree=Pos	_	_	_	_
42	as	_	ADP	_	_	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
45	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
46	line	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	present	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	evidence	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	II	_	NUM	_	NumType=Card	_	_	_	_
14	functions	_	NOUN	_	Number=Plur	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	repressor	_	NOUN	_	Number=Sing	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	6	_	NUM	_	NumType=Card	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	related	_	ADJ	_	Degree=Pos	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	motifs	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011583	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Monocyte	_	ADJ	_	Number=Sing	_	_	_	_
2	arrest	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	transmigration	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	inflamed	_	VERB	_	Degree=Pos	_	_	_	_
7	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	shear	_	ADJ	_	Degree=Pos	_	_	_	_
10	flow	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	adenovirus	_	ADJ	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	transfer	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Mobilization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
17	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
18	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
19	molecules	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	chemokines	_	NOUN	_	Number=Plur	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	contribute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	monocyte	_	VERB	_	VerbForm=Inf	_	_	_	_
26	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
27	critical	_	ADJ	_	Degree=Pos	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	atherogenesis	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	achieved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	pharmacological	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
13	approaches	_	NOUN	_	Number=Plur	_	_	_	_
14	;	_	PUNCT	_	_	_	_	_	_
15	however	_	ADV	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	monocyte	_	ADJ	_	Degree=Pos	_	_	_	_
18	interactions	_	NOUN	_	Number=Plur	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	shear	_	ADJ	_	Degree=Pos	_	_	_	_
24	flow	_	NOUN	_	Number=Sing	_	_	_	_
25	following	_	VERB	_	VerbForm=Ger	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	transfer	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
33	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
34	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	not	_	PART	_	_	_	_	_	_
39	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
40	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	using	_	VERB	_	VerbForm=Ger	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
15	adenovirus	_	NOUN	_	Number=Sing	_	_	_	_
16	prevented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	tumor	_	NOUN	_	Number=Sing	_	_	_	_
18	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	TNF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	degradation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
42	molecule	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	1	_	NUM	_	NumType=Card	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
52	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
53	molecule	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	1	_	NUM	_	NumType=Card	_	_	_	_
56	(	_	PUNCT	_	_	_	_	_	_
57	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	1	_	NUM	_	NumType=Card	_	_	_	_
60	)	_	PUNCT	_	_	_	_	_	_
61	,	_	PUNCT	_	_	_	_	_	_
62	and	_	CCONJ	_	_	_	_	_	_
63	E-selectin	_	ADJ	_	Degree=Pos	_	_	_	_
64	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
65	and	_	CCONJ	_	_	_	_	_	_
66	surface	_	NOUN	_	Number=Sing	_	_	_	_
67	protein	_	NOUN	_	Number=Sing	_	_	_	_
68	expression	_	NOUN	_	Number=Sing	_	_	_	_
69	and	_	CCONJ	_	_	_	_	_	_
70	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
71	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
72	of	_	ADP	_	_	_	_	_	_
73	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
74	for	_	ADP	_	_	_	_	_	_
75	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
76	chemokines	_	NOUN	_	Number=Plur	_	_	_	_
77	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
78	chemoattractant	_	NOUN	_	Number=Sing	_	_	_	_
79	protein	_	NOUN	_	Number=Sing	_	_	_	_
80	1	_	NUM	_	NumType=Card	_	_	_	_
81	(	_	PUNCT	_	_	_	_	_	_
82	MCP	_	NOUN	_	Number=Sing	_	_	_	_
83	-	_	PUNCT	_	_	_	_	_	_
84	1	_	NUM	_	NumType=Card	_	_	_	_
85	)	_	PUNCT	_	_	_	_	_	_
86	and	_	CCONJ	_	_	_	_	_	_
87	growth	_	NOUN	_	Number=Sing	_	_	_	_
88	-	_	PUNCT	_	_	_	_	_	_
89	related	_	ADJ	_	Degree=Pos	_	_	_	_
90	activity	_	NOUN	_	Number=Sing	_	_	_	_
91	-	_	PUNCT	_	_	_	_	_	_
92	alpha	_	NOUN	_	Number=Sing	_	_	_	_
93	(	_	PUNCT	_	_	_	_	_	_
94	GRO	_	PROPN	_	Number=Sing	_	_	_	_
95	-	_	PUNCT	_	_	_	_	_	_
96	alpha	_	NOUN	_	Number=Sing	_	_	_	_
97	)	_	PUNCT	_	_	_	_	_	_
98	by	_	ADP	_	_	_	_	_	_
99	TNF	_	PROPN	_	Number=Sing	_	_	_	_
100	-	_	PUNCT	_	_	_	_	_	_
101	alpha	_	NOUN	_	Number=Sing	_	_	_	_
102	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	reduction	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	endothelial	_	NOUN	_	Number=Sing	_	_	_	_
9	MCP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	secretion	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	GRO	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	immobilization	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Adhesion	_	NOUN	_	Number=Sing	_	_	_	_
2	assays	_	NOUN	_	Number=Plur	_	_	_	_
3	under	_	ADP	_	_	_	_	_	_
4	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
5	shear	_	NOUN	_	Degree=Pos	_	_	_	_
6	flow	_	NOUN	_	Number=Sing	_	_	_	_
7	conditions	_	NOUN	_	Number=Plur	_	_	_	_
8	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	firm	_	ADJ	_	Degree=Pos	_	_	_	_
11	arrest	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	spreading	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	transmigration	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	TNF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	markedly	_	ADV	_	_	_	_	_	_
28	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	alpha	_	NOUN	_	Number=Sing	_	_	_	_
33	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
4	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	peptide	_	NOUN	_	Degree=Pos	_	_	_	_
7	antagonists	_	NOUN	_	Number=Plur	_	_	_	_
8	inferred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	due	_	ADP	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Ig	_	PROPN	_	Number=Sing	_	_	_	_
18	integrin	_	PROPN	_	Number=Sing	_	_	_	_
19	ligand	_	NOUN	_	Number=Sing	_	_	_	_
20	as	_	ADV	_	_	_	_	_	_
21	well	_	ADV	_	Degree=Pos	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	chemokines	_	NOUN	_	Number=Plur	_	_	_	_
25	specifically	_	ADV	_	_	_	_	_	_
26	involved	_	ADJ	_	Degree=Pos	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	events	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	rolling	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	transfer	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	partly	_	ADV	_	_	_	_	_	_
17	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	P	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	selectin	_	NOUN	_	Number=Sing	_	_	_	_
22	;	_	PUNCT	_	_	_	_	_	_
23	however	_	ADV	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
26	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	be	_	AUX	_	VerbForm=Inf	_	_	_	_
29	unaffected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	E	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	selectin	_	NOUN	_	Number=Sing	_	_	_	_
37	induction	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	novel	_	NOUN	_	Number=Sing	_	_	_	_
7	evidence	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	PronType=Rel	_	_	_	_
9	selective	_	ADJ	_	Degree=Pos	_	_	_	_
10	modulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	adenoviral	_	ADJ	_	Degree=Pos	_	_	_	_
17	transfer	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	impairs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
27	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	products	_	NOUN	_	Number=Plur	_	_	_	_
30	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
33	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
34	arrest	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	emigration	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	shear	_	ADJ	_	Degree=Pos	_	_	_	_
39	flow	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	thus	_	ADV	_	_	_	_	_	_
42	for	_	ADP	_	_	_	_	_	_
43	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
44	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	atherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
47	plaques	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011588	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	downregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
11	myeloma	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	lines	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	belonging	_	VERB	_	VerbForm=Ger	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	Ets	_	NOUN	_	Number=Plur	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	family	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identical	_	ADJ	_	Degree=Pos	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	Spi	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	spleen	_	ADJ	_	Degree=Pos	_	_	_	_
16	focus	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
19	virus	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	murine	_	NOUN	_	Number=Sing	_	_	_	_
23	erythroleukemias	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	PU.	_	NOUN	_	Number=Sing	_	_	_	_
2	1	_	NUM	_	NumType=Card	_	_	_	_
3	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	early	_	ADJ	_	Degree=Pos	_	_	_	_
9	development	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
12	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
13	lineages	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	mature	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	preferentially	_	ADV	_	_	_	_	_	_
23	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
38	lineage	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	so	_	ADV	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	Pu	_	PROPN	_	Number=Sing	_	_	_	_
8	box	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	important	_	ADJ	_	Degree=Pos	_	_	_	_
12	tissue	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	element	_	NOUN	_	Number=Sing	_	_	_	_
18	present	_	VERB	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	number	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	lineages	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	PU.	_	NOUN	_	Number=Sing	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	development	_	NOUN	_	Number=Sing	_	_	_	_
17	using	_	VERB	_	VerbForm=Ger	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	panel	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	lines	_	NOUN	_	Number=Plur	_	_	_	_
25	representing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	different	_	ADJ	_	Degree=Pos	_	_	_	_
27	stages	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	maturation	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	early	_	ADJ	_	Degree=Pos	_	_	_	_
33	precursors	_	NOUN	_	Number=Plur	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	differentiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	plasma	_	NOUN	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
2	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
6	DNA	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	as	_	SCONJ	_	_	_	_	_	_
11	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
14	blot	_	NOUN	_	Number=Sing	_	_	_	_
15	analysis	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
18	mobility	_	NOUN	_	Number=Sing	_	_	_	_
19	shift	_	NOUN	_	Number=Sing	_	_	_	_
20	assay	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	respectively	_	ADV	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	evident	_	ADJ	_	Degree=Pos	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	lines	_	NOUN	_	Number=Plur	_	_	_	_
29	representing	_	VERB	_	VerbForm=Ger	_	_	_	_
30	pro-B	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	mature	_	ADJ	_	Degree=Pos	_	_	_	_
36	B	_	ADJ	_	Degree=Pos	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	could	_	AUX	_	VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	show	_	VERB	_	VerbForm=Inf	_	_	_	_
5	Pu	_	PROPN	_	Number=Sing	_	_	_	_
6	box	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	reporter	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	transient	_	ADJ	_	Degree=Pos	_	_	_	_
16	transfections	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	lines	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	number	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
9	myeloma	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	lines	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	representing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	differentiated	_	ADJ	_	Degree=Pos	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	plasma	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	like	_	ADP	_	_	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
24	DNA	_	NOUN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	Pu	_	NOUN	_	Number=Sing	_	_	_	_
33	box	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
36	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
37	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	absent	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	or	_	CCONJ	_	_	_	_	_	_
40	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
41	at	_	ADP	_	_	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	very	_	ADV	_	_	_	_	_	_
44	low	_	ADJ	_	Degree=Pos	_	_	_	_
45	level	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	lymphoblastoid	_	ADJ	_	Degree=Pos	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	exemplify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	intermediate	_	ADJ	_	Degree=Pos	_	_	_	_
10	stage	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
7	myeloma	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	lines	_	NOUN	_	Number=Plur	_	_	_	_
10	represent	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
13	examples	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	B	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	downregulated	_	VERB	_	Degree=Pos	_	_	_	_
19	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	apparently	_	ADV	_	_	_	_	_	_
23	contradict	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	observations	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	murine	_	NOUN	_	Number=Sing	_	_	_	_
28	system	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	which	_	PRON	_	PronType=Rel	_	_	_	_
31	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	expressed	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	active	_	ADJ	_	Degree=Pos	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	plasmacytoma	_	ADJ	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	lines	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	whether	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	lack	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
18	myeloma	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	lines	_	NOUN	_	Number=Plur	_	_	_	_
21	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	malignancy	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	defect	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	exemplifies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	normal	_	ADJ	_	Degree=Pos	_	_	_	_
34	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
35	regulation	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	terminally	_	ADV	_	_	_	_	_	_
38	differentiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	B	_	ADJ	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011591	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	v-src	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	PROPN	_	Number=Sing	_	_	_	_
15	B.	_	PROPN	_	Number=Sing	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	rapidly	_	ADV	_	_	_	_	_	_
23	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	activator	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	responds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	variety	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	signals	_	NOUN	_	Number=Plur	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	influences	_	NOUN	_	Number=Plur	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	many	_	ADJ	_	Degree=Pos	_	_	_	_
39	genes	_	NOUN	_	Number=Plur	_	_	_	_
40	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	immune	_	ADJ	_	Degree=Pos	_	_	_	_
44	response	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
3	kinases	_	NOUN	_	Number=Plur	_	_	_	_
4	transmit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	signals	_	NOUN	_	Number=Plur	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	immune	_	ADJ	_	Degree=Pos	_	_	_	_
10	receptors	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Very	_	ADV	_	_	_	_	_	_
2	little	_	ADJ	_	Degree=Pos	_	_	_	_
3	information	_	NOUN	_	Number=Sing	_	_	_	_
4	exists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	important	_	ADJ	_	Degree=Pos	_	_	_	_
9	classes	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
12	molecules	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	v-src	_	ADJ	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	complex	_	NOUN	_	Number=Sing	_	_	_	_
17	similar	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
23	ester	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	as	_	SCONJ	_	_	_	_	_	_
28	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
31	mobility	_	NOUN	_	Number=Sing	_	_	_	_
32	shift	_	NOUN	_	Number=Sing	_	_	_	_
33	assay	_	NOUN	_	Number=Sing	_	_	_	_
34	using	_	VERB	_	VerbForm=Ger	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	variety	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	kappa	_	NOUN	_	Number=Sing	_	_	_	_
39	B	_	NOUN	_	Number=Sing	_	_	_	_
40	sites	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	complex	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	herbimycin	_	NOUN	_	Number=Sing	_	_	_	_
12	A	_	PROPN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	v-src	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	complex	_	NOUN	_	Number=Sing	_	_	_	_
6	comprised	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	p50	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	p65	_	NOUN	_	Number=Sing	_	_	_	_
11	components	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	as	_	SCONJ	_	_	_	_	_	_
19	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	supershift	_	ADJ	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	immunoblot	_	ADJ	_	Number=Sing	_	_	_	_
24	analysis	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	functional	_	ADJ	_	Degree=Pos	_	_	_	_
4	correlate	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	finding	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	transient	_	ADJ	_	Degree=Pos	_	_	_	_
10	co-transfection	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	LTR	_	NOUN	_	Number=Sing	_	_	_	_
16	reporter	_	NOUN	_	Number=Sing	_	_	_	_
17	constructs	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	different	_	ADJ	_	Degree=Pos	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	v-src	_	PROPN	_	Number=Sing	_	_	_	_
27	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
36	manner	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	HIV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	LTR	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	v-src	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	more	_	ADV	_	_	_	_	_	_
15	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	mutations	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	proximal	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	rather	_	ADV	_	_	_	_	_	_
23	than	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	distal	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	element	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	implications	_	NOUN	_	Number=Plur	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	signaling	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	considered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011592	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Comparison	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
8	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	kappa	_	PROPN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	related	_	ADJ	_	Degree=Pos	_	_	_	_
14	sequences	_	NOUN	_	Number=Plur	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	modulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	B	_	ADJ	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
25	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
26	virus	_	NOUN	_	Number=Sing	_	_	_	_
27	type	_	NOUN	_	Number=Sing	_	_	_	_
28	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
29	tax	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	kappa	_	NOUN	_	Number=Sing	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	sequence	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	GGGACTTTCC	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	PROPN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	constitutively	_	ADV	_	_	_	_	_	_
20	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	functional	_	ADJ	_	Degree=Pos	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	DNA	_	PROPN	_	Number=Sing	_	_	_	_
26	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
27	form	_	NOUN	_	Number=Sing	_	_	_	_
28	only	_	ADV	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	B	_	ADJ	_	Number=Sing	_	_	_	_
31	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	apparently	_	ADV	_	_	_	_	_	_
5	indistinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	specificity	_	NOUN	_	Number=Sing	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	many	_	ADJ	_	Degree=Pos	_	_	_	_
13	other	_	ADJ	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	types	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	where	_	ADV	_	PronType=Rel	_	_	_	_
18	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	example	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	related	_	ADJ	_	Degree=Pos	_	_	_	_
8	sequences	_	NOUN	_	Number=Plur	_	_	_	_
9	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	important	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	few	_	ADJ	_	Degree=Pos	_	_	_	_
21	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	such	_	ADJ	_	Degree=Pos	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	chain	_	NOUN	_	Number=Sing	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	beta	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	interferon	_	NOUN	_	Degree=Pos	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	genes	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	constitutively	_	ADV	_	_	_	_	_	_
8	active	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	B	_	ADJ	_	Degree=Pos	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	other	_	ADJ	_	Degree=Pos	_	_	_	_
16	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
18	must	_	AUX	_	VerbForm=Fin	_	_	_	_
19	play	_	VERB	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	SCONJ	_	_	_	_	_	_
23	determining	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	patterns	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	five	_	NUM	_	NumType=Card	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	related	_	ADJ	_	Degree=Pos	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	elements	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	two	_	NUM	_	NumType=Card	_	_	_	_
21	different	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	types	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	S194	_	NUM	_	NumType=Card	_	_	_	_
6	plasma	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	each	_	DET	_	_	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	well	_	ADV	_	Degree=Pos	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	relative	_	ADJ	_	Degree=Pos	_	_	_	_
18	affinity	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	B	_	ADJ	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	NF	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	element	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	significantly	_	ADV	_	_	_	_	_	_
5	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	sites	_	NOUN	_	Number=Plur	_	_	_	_
10	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	S194	_	NUM	_	NumType=Card	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	either	_	CCONJ	_	_	_	_	_	_
5	EL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	X	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	S194	_	NUM	_	NumType=Card	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	both	_	CCONJ	_	_	_	_	_	_
17	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	affinity	_	NOUN	_	Number=Sing	_	_	_	_
20	sites	_	NOUN	_	Number=Plur	_	_	_	_
21	can	_	AUX	_	VerbForm=Fin	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	significantly	_	ADV	_	_	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	tax	_	NOUN	_	Number=Sing	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	product	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
33	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
34	virus	_	NOUN	_	Number=Sing	_	_	_	_
35	type	_	NOUN	_	Number=Sing	_	_	_	_
36	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	showing	_	VERB	_	VerbForm=Ger	_	_	_	_
39	that	_	SCONJ	_	_	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappa	_	NOUN	_	Number=Sing	_	_	_	_
43	B	_	NOUN	_	Number=Sing	_	_	_	_
44	activity	_	NOUN	_	Number=Sing	_	_	_	_
45	can	_	AUX	_	VerbForm=Fin	_	_	_	_
46	be	_	AUX	_	VerbForm=Inf	_	_	_	_
47	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	even	_	ADV	_	_	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
51	B	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	cell	_	NOUN	_	Number=Sing	_	_	_	_
54	line	_	NOUN	_	Number=Sing	_	_	_	_
55	that	_	PRON	_	PronType=Rel	_	_	_	_
56	constitutively	_	ADV	_	_	_	_	_	_
57	expresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
58	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
59	factor	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011593	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	differences	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	elements	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	interferon	_	NOUN	_	Number=Sing	_	_	_	_
21	promoters	_	NOUN	_	Number=Plur	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	tumor	_	NOUN	_	Number=Sing	_	_	_	_
24	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Three	_	NUM	_	NumType=Card	_	_	_	_
2	aspects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	involvement	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	tumor	_	NOUN	_	Number=Sing	_	_	_	_
8	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	TNF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
16	chain	_	NOUN	_	Number=Sing	_	_	_	_
17	reaction	_	NOUN	_	Number=Sing	_	_	_	_
18	amplification	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
21	U937	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	chronically	_	ADV	_	_	_	_	_	_
27	HIV	_	NOUN	_	Number=Sing	_	_	_	_
28	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	U937	_	NOUN	_	Number=Sing	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	line	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	U9	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	IIIB	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	PROPN	_	Number=Sing	_	_	_	_
4	RNA	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	undetectable	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	U937	_	NUM	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	whereas	_	SCONJ	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	low	_	ADJ	_	Degree=Pos	_	_	_	_
14	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	U9	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	IIIB	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Paramyxovirus	_	NOUN	_	Number=Sing	_	_	_	_
2	infection	_	NOUN	_	Number=Sing	_	_	_	_
3	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	10	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	fold	_	NOUN	_	Number=Sing	_	_	_	_
11	increase	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	steady	_	ADJ	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	state	_	NOUN	_	Number=Sing	_	_	_	_
17	level	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	TNF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	PROPN	_	Number=Sing	_	_	_	_
22	RNA	_	PROPN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	U9	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	IIIB	_	PROPN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	U937	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
34	that	_	SCONJ	_	_	_	_	_	_
35	HIV	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
42	levels	_	NOUN	_	Number=Plur	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	TNF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	alpha	_	NOUN	_	Number=Sing	_	_	_	_
47	than	_	SCONJ	_	_	_	_	_	_
48	did	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
49	normal	_	ADJ	_	Degree=Pos	_	_	_	_
50	cells	_	NOUN	_	Number=Plur	_	_	_	_
51	after	_	ADP	_	_	_	_	_	_
52	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
53	secondary	_	ADJ	_	Degree=Pos	_	_	_	_
54	virus	_	NOUN	_	Number=Sing	_	_	_	_
55	infection	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	transient	_	ADJ	_	Degree=Pos	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	assays	_	NOUN	_	Number=Plur	_	_	_	_
16	using	_	VERB	_	VerbForm=Ger	_	_	_	_
17	reporter	_	NOUN	_	Number=Sing	_	_	_	_
18	chloramphenicol	_	PROPN	_	Number=Sing	_	_	_	_
19	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
20	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
21	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	elements	_	NOUN	_	Number=Plur	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	HIV	_	PROPN	_	Number=Sing	_	_	_	_
28	long	_	ADJ	_	Degree=Pos	_	_	_	_
29	terminal	_	NOUN	_	Number=Sing	_	_	_	_
30	repeat	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	LTR	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	beta	_	NOUN	_	Number=Sing	_	_	_	_
37	interferon	_	NOUN	_	Number=Sing	_	_	_	_
38	promoter	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	U937	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	different	_	ADJ	_	Degree=Pos	_	_	_	_
14	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
15	promoters	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	TNF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
22	ester	_	NOUN	_	Number=Sing	_	_	_	_
23	varied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	type	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	promoter	_	ADJ	_	Degree=Pos	_	_	_	_
31	context	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	specific	_	ADJ	_	Degree=Pos	_	_	_	_
34	manner	_	NOUN	_	Number=Sing	_	_	_	_
35	;	_	PUNCT	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	levels	_	NOUN	_	Number=Plur	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	activity	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	NF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	kappa	_	NOUN	_	Number=Sing	_	_	_	_
45	B	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
48	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
49	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	directly	_	ADV	_	_	_	_	_	_
51	with	_	ADP	_	_	_	_	_	_
52	induction	_	NOUN	_	Number=Sing	_	_	_	_
53	of	_	ADP	_	_	_	_	_	_
54	NF	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	kappa	_	NOUN	_	Number=Sing	_	_	_	_
57	B	_	NOUN	_	Number=Sing	_	_	_	_
58	DNA	_	NOUN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	binding	_	NOUN	_	Number=Sing	_	_	_	_
61	activity	_	NOUN	_	Number=Sing	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	intact	_	NOUN	_	Number=Sing	_	_	_	_
4	beta	_	NOUN	_	Number=Sing	_	_	_	_
5	interferon	_	NOUN	_	Number=Sing	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	only	_	ADV	_	_	_	_	_	_
9	weakly	_	ADV	_	_	_	_	_	_
10	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
13	ester	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	TNF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	multimers	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	PRDII	_	PROPN	_	Number=Sing	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	binding	_	VERB	_	Number=Sing	_	_	_	_
29	domain	_	NOUN	_	Number=Sing	_	_	_	_
30	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	both	_	DET	_	_	_	_	_	_
34	agents	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	able	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	LTR	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	TNF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	HIV	_	PROPN	_	Number=Sing	_	_	_	_
30	LTR	_	NOUN	_	Number=Sing	_	_	_	_
31	above	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
34	level	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	activity	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	level	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	independent	_	ADJ	_	Degree=Pos	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	multiplication	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	since	_	SCONJ	_	_	_	_	_	_
20	TNF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	treatment	_	NOUN	_	Number=Sing	_	_	_	_
24	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	no	_	DET	_	_	_	_	_	_
26	effect	_	NOUN	_	Number=Sing	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	de	_	X	_	Number=Sing	_	_	_	_
32	novo	_	PROPN	_	Number=Sing	_	_	_	_
33	HIV	_	NOUN	_	Number=Sing	_	_	_	_
34	type	_	NOUN	_	Number=Sing	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	HIV	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	infection	_	NOUN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	viral	_	ADJ	_	Degree=Pos	_	_	_	_
44	RNA	_	NOUN	_	Number=Sing	_	_	_	_
45	production	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	U937	_	NOUN	_	Number=Sing	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	dramatically	_	ADV	_	_	_	_	_	_
11	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	spread	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	population	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	viral	_	ADJ	_	Degree=Pos	_	_	_	_
25	RNA	_	PROPN	_	Number=Sing	_	_	_	_
26	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	T	_	PROPN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	HIV	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	multiplication	_	NOUN	_	Number=Sing	_	_	_	_
37	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
38	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	TNF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	alpha	_	NOUN	_	Number=Sing	_	_	_	_
43	treatment	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011601	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Polymorphic	_	ADJ	_	Degree=Pos	_	_	_	_
2	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
3	within	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Atopy	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	which	_	PRON	_	PronType=Rel	_	_	_	_
4	predisposes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	individuals	_	NOUN	_	Number=Plur	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	develop	_	VERB	_	VerbForm=Inf	_	_	_	_
8	asthma	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	severe	_	ADJ	_	Degree=Pos	_	_	_	_
11	systemic	_	ADJ	_	Degree=Pos	_	_	_	_
12	anaphylaxis	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	atopic	_	ADJ	_	Degree=Pos	_	_	_	_
16	dermatitis	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	usually	_	ADV	_	_	_	_	_	_
20	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	dramatically	_	ADV	_	_	_	_	_	_
23	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	total	_	ADJ	_	Degree=Pos	_	_	_	_
25	serum	_	NOUN	_	Number=Sing	_	_	_	_
26	IgE	_	NOUN	_	Number=Sing	_	_	_	_
27	levels	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	be	_	AUX	_	VerbForm=Inf	_	_	_	_
33	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	major	_	ADJ	_	Degree=Pos	_	_	_	_
37	susceptibility	_	NOUN	_	Number=Sing	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
41	minor	_	ADJ	_	Degree=Pos	_	_	_	_
42	susceptibility	_	NOUN	_	Number=Sing	_	_	_	_
43	genes	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	recent	_	ADJ	_	Degree=Pos	_	_	_	_
3	sib	_	NUM	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	pair	_	NOUN	_	Number=Sing	_	_	_	_
6	analysis	_	NOUN	_	Number=Sing	_	_	_	_
7	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	tight	_	ADJ	_	Degree=Pos	_	_	_	_
10	linkage	_	NOUN	_	Number=Sing	_	_	_	_
11	between	_	ADP	_	_	_	_	_	_
12	markers	_	NOUN	_	Number=Plur	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	5q31.1	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	major	_	ADJ	_	Degree=Pos	_	_	_	_
18	susceptibility	_	NOUN	_	Number=Sing	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
21	total	_	ADJ	_	Degree=Pos	_	_	_	_
22	serum	_	NOUN	_	Number=Sing	_	_	_	_
23	IgE	_	NOUN	_	Number=Sing	_	_	_	_
24	levels	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Due	_	ADP	_	_	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
4	location	_	NOUN	_	Number=Sing	_	_	_	_
5	within	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	cluster	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	biologic	_	ADJ	_	Degree=Pos	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	Ig	_	PROPN	_	Number=Sing	_	_	_	_
14	class	_	NOUN	_	Number=Sing	_	_	_	_
15	switching	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	emerged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	one	_	NUM	_	NumType=Card	_	_	_	_
30	major	_	ADJ	_	Degree=Pos	_	_	_	_
31	candidate	_	NOUN	_	Number=Sing	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	atopy	_	NOUN	_	Degree=Pos	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	one	_	NUM	_	NumType=Card	_	_	_	_
3	model	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	polymorphisms	_	NOUN	_	Number=Plur	_	_	_	_
6	within	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	4	_	NUM	_	NumType=Card	_	_	_	_
10	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	elements	_	NOUN	_	Number=Plur	_	_	_	_
12	might	_	AUX	_	VerbForm=Fin	_	_	_	_
13	result	_	VERB	_	VerbForm=Inf	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	amplifying	_	VERB	_	VerbForm=Ger	_	_	_	_
21	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	class	_	NOUN	_	Number=Sing	_	_	_	_
26	switching	_	VERB	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	IgE	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	support	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	model	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	exists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
19	allelic	_	NOUN	_	Degree=Pos	_	_	_	_
20	forms	_	NOUN	_	Number=Plur	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	exhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	activities	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	4	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	positive	_	ADJ	_	Degree=Pos	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	particular	_	ADJ	_	Degree=Pos	_	_	_	_
3	allele	_	NOUN	_	Number=Sing	_	_	_	_
4	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	unusually	_	ADV	_	_	_	_	_	_
7	high	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
3	substitution	_	NOUN	_	Number=Sing	_	_	_	_
4	within	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	recently	_	ADV	_	_	_	_	_	_
7	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	OAP40	_	PROPN	_	Number=Sing	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	just	_	ADV	_	_	_	_	_	_
12	upstream	_	ADV	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	AT	_	ADP	_	_	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	P	_	NOUN	_	Number=Sing	_	_	_	_
21	sequence	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	largely	_	ADV	_	_	_	_	_	_
27	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	promotor	_	NOUN	_	Number=Sing	_	_	_	_
32	strength	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
35	particular	_	ADJ	_	Degree=Pos	_	_	_	_
36	allelic	_	ADJ	_	Degree=Pos	_	_	_	_
37	form	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	4	_	NUM	_	NumType=Card	_	_	_	_
43	promoter	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	EMSAs	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	substitution	_	NOUN	_	Number=Sing	_	_	_	_
6	results	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	markedly	_	ADV	_	_	_	_	_	_
10	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	affinity	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	sequence	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	complexes	_	NOUN	_	Number=Plur	_	_	_	_
17	exhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	AP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	specificity	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	identification	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	allelic	_	ADJ	_	Degree=Pos	_	_	_	_
5	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	DET	_	PronType=Rel	_	_	_	_
8	results	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	targets	_	NOUN	_	Number=Plur	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	comprehensive	_	ADJ	_	Degree=Pos	_	_	_	_
24	screening	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	atopic	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	nonatopic	_	ADJ	_	Degree=Pos	_	_	_	_
29	individuals	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	may	_	AUX	_	VerbForm=Fin	_	_	_	_
32	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	clue	_	NOUN	_	Number=Sing	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
37	predisposition	_	NOUN	_	Number=Sing	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	atopy	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011602	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Comparative	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	complex	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
13	activator	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	sequences	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	be	_	AUX	_	VerbForm=Inf	_	_	_	_
34	largely	_	ADV	_	_	_	_	_	_
35	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	T	_	PROPN	_	Number=Sing	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	specific	_	ADJ	_	Degree=Pos	_	_	_	_
42	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	IL	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	2	_	NUM	_	NumType=Card	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	NFAT	_	NOUN	_	Degree=Pos	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	could	_	AUX	_	VerbForm=Fin	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	B	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
5	complex	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	however	_	ADV	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	functional	_	ADJ	_	Degree=Pos	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	since	_	SCONJ	_	_	_	_	_	_
14	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
15	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	chloramphenicol	_	NOUN	_	Number=Sing	_	_	_	_
25	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	CAT	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	construct	_	VERB	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Competition	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	motif	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	anti-Jun	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	anti-Fos	_	NOUN	_	Degree=Pos	_	_	_	_
13	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
14	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
19	motif	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	both	_	CCONJ	_	_	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	B	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	Jun	_	PROPN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	Fos	_	PROPN	_	Number=Sing	_	_	_	_
32	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	critical	_	ADJ	_	Degree=Pos	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
36	complex	_	ADJ	_	Number=Sing	_	_	_	_
37	formation	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	both	_	DET	_	_	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	types	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	recombinant	_	PROPN	_	Number=Sing	_	_	_	_
3	Jun	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Fos	_	PROPN	_	Number=Sing	_	_	_	_
6	proteins	_	NOUN	_	Number=Plur	_	_	_	_
7	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
10	directly	_	ADV	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
14	motif	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	when	_	ADV	_	PronType=Int	_	_	_	_
4	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	T	_	PROPN	_	NumType=Card	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	extracts	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	full	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	length	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	not	_	ADV	_	_	_	_	_	_
19	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	Jun	_	PROPN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	Fos	_	PROPN	_	Number=Sing	_	_	_	_
24	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
25	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	able	_	ADJ	_	Degree=Pos	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	form	_	VERB	_	VerbForm=Inf	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
31	complex	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	presence	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	constitutively	_	ADV	_	_	_	_	_	_
39	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
41	factor	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	s	_	X	_	_	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	B	_	ADJ	_	Degree=Pos	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	T	_	PROPN	_	Number=Sing	_	_	_	_
49	cells	_	NOUN	_	Number=Plur	_	_	_	_
50	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
51	for	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	formation	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
57	complex	_	NOUN	_	Number=Sing	_	_	_	_
58	in	_	ADP	_	_	_	_	_	_
59	both	_	DET	_	_	_	_	_	_
60	cell	_	NOUN	_	Number=Sing	_	_	_	_
61	types	_	NOUN	_	Number=Plur	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
3	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
4	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
5	mutations	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	'	_	PUNCT	_	_	_	_	_	_
10	purine	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	rich	_	ADJ	_	Degree=Pos	_	_	_	_
13	part	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	form	_	VERB	_	VerbForm=Inf	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	complex	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	compete	_	VERB	_	VerbForm=Inf	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	wild	_	NOUN	_	Number=Sing	_	_	_	_
29	type	_	NOUN	_	Number=Sing	_	_	_	_
30	motif	_	NOUN	_	Number=Sing	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
33	complex	_	ADJ	_	Number=Sing	_	_	_	_
34	formation	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	both	_	CCONJ	_	_	_	_	_	_
37	T	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	B	_	ADJ	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	model	_	NOUN	_	Number=Sing	_	_	_	_
6	whereby	_	ADV	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	core	_	NOUN	_	Number=Sing	_	_	_	_
9	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
10	complex	_	NOUN	_	Number=Sing	_	_	_	_
11	consisting	_	VERB	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Jun	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	Fos	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	formed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	both	_	CCONJ	_	_	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	B	_	ADJ	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	but	_	CCONJ	_	_	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	additional	_	ADJ	_	Degree=Pos	_	_	_	_
34	factor	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	post-translational	_	ADJ	_	Degree=Pos	_	_	_	_
39	modification	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	factor	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	missing	_	VERB	_	Degree=Pos	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	B	_	ADJ	_	Degree=Pos	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	might	_	AUX	_	VerbForm=Fin	_	_	_	_
50	be	_	AUX	_	VerbForm=Inf	_	_	_	_
51	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	for	_	ADP	_	_	_	_	_	_
53	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
54	by	_	ADP	_	_	_	_	_	_
55	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011619	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Dimethyldithiocarbamate	_	ADJ	_	Degree=Pos	_	_	_	_
2	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vitro	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	primary	_	ADJ	_	Degree=Pos	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	CD4	_	NOUN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	Dithiocarbamates	_	PROPN	_	Number=Plur	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	DTC	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
8	group	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	industrial	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
13	chemicals	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	inhibit	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	enhance	_	VERB	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	no	_	DET	_	_	_	_	_	_
25	effect	_	NOUN	_	Number=Sing	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	immune	_	NOUN	_	Number=Sing	_	_	_	_
29	system	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
3	inconsistencies	_	NOUN	_	Number=Plur	_	_	_	_
4	reflect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	complexity	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	DTCs	_	NOUN	_	Number=Plur	_	_	_	_
10	biological	_	ADJ	_	Degree=Pos	_	_	_	_
11	activities	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	probably	_	ADV	_	_	_	_	_	_
15	due	_	ADP	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	part	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	differences	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	dose	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	route	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	exposure	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	animal	_	NOUN	_	Number=Sing	_	_	_	_
28	species	_	NOUN	_	Number=Plur	_	_	_	_
29	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	specific	_	ADJ	_	Degree=Pos	_	_	_	_
34	compound	_	NOUN	_	Number=Sing	_	_	_	_
35	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	herein	_	ADV	_	_	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	undertaken	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	immunotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	one	_	NUM	_	NumType=Card	_	_	_	_
13	member	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	family	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	dimethyldithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	DMDTC	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	0.1	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	SYM	_	_	_	_	_	_
6	0.5	_	NUM	_	NumType=Card	_	_	_	_
7	microM	_	NUM	_	Number=Sing	_	_	_	_
8	DMDTC	_	PROPN	_	Number=Sing	_	_	_	_
9	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	TNF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	primary	_	ADJ	_	Degree=Pos	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	CD4	_	NOUN	_	Number=Sing	_	_	_	_
24	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	loss	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	viability	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	DMDTC	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	retain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	other	_	ADJ	_	Degree=Pos	_	_	_	_
20	active	_	ADJ	_	Degree=Pos	_	_	_	_
21	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
22	pathways	_	NOUN	_	Number=Plur	_	_	_	_
23	throughout	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	exposure	_	NOUN	_	Number=Sing	_	_	_	_
26	duration	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	apparently	_	ADV	_	_	_	_	_	_
9	permanent	_	ADJ	_	Degree=Pos	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	DMDTC	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	regain	_	VERB	_	VerbForm=Inf	_	_	_	_
19	normal	_	ADJ	_	Degree=Pos	_	_	_	_
20	TNF	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	even	_	ADV	_	_	_	_	_	_
26	after	_	ADP	_	_	_	_	_	_
27	72	_	NUM	_	NumType=Card	_	_	_	_
28	h	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	culture	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	DMDTC	_	PROPN	_	Number=Sing	_	_	_	_
2	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	appear	_	VERB	_	VerbForm=Inf	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	directly	_	ADV	_	_	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	pre-incubation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	extracts	_	NOUN	_	Number=Plur	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	DMDTC	_	PROPN	_	Number=Sing	_	_	_	_
18	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	diminish	_	VERB	_	VerbForm=Inf	_	_	_	_
21	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	0.1	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	SYM	_	_	_	_	_	_
7	0.5	_	NUM	_	NumType=Card	_	_	_	_
8	microM	_	NUM	_	Number=Sing	_	_	_	_
9	DMDTC	_	PROPN	_	Number=Sing	_	_	_	_
10	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
11	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	production	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	decreases	_	NOUN	_	Number=Plur	_	_	_	_
18	surface	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	CD25	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	subunit	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	receptor	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	T	_	PROPN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
39	ester	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	DMDTC	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	potent	_	ADJ	_	Degree=Pos	_	_	_	_
9	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
10	compound	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	vitro	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011620	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Distinctive	_	ADJ	_	Degree=Pos	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	patterns	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	mammary	_	ADJ	_	Number=Sing	_	_	_	_
8	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	breast	_	NOUN	_	Number=Sing	_	_	_	_
12	cancers	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
2	microarrays	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	clustering	_	NOUN	_	Number=Sing	_	_	_	_
6	algorithm	_	NOUN	_	Number=Sing	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
11	patterns	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	mammary	_	ADJ	_	Number=Sing	_	_	_	_
18	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	growing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	culture	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	primary	_	ADJ	_	Degree=Pos	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	breast	_	NOUN	_	Number=Sing	_	_	_	_
28	tumors	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Clusters	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	coexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
4	genes	_	NOUN	_	Number=Plur	_	_	_	_
5	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	through	_	ADP	_	_	_	_	_	_
7	manipulations	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	mammary	_	ADJ	_	Degree=Pos	_	_	_	_
10	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vitro	_	NOUN	_	Number=Sing	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
17	patterns	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	variation	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	among	_	ADP	_	_	_	_	_	_
23	breast	_	NOUN	_	Number=Sing	_	_	_	_
24	tumor	_	NOUN	_	Number=Sing	_	_	_	_
25	samples	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	immunohistochemistry	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
6	against	_	ADP	_	_	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	particular	_	ADJ	_	Degree=Pos	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	cluster	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	identity	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	within	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	tumor	_	NOUN	_	Number=Sing	_	_	_	_
26	specimen	_	NOUN	_	Number=Sing	_	_	_	_
27	that	_	PRON	_	PronType=Rel	_	_	_	_
28	contributed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	pattern	_	NOUN	_	Number=Sing	_	_	_	_
34	could	_	AUX	_	VerbForm=Fin	_	_	_	_
35	be	_	AUX	_	VerbForm=Inf	_	_	_	_
36	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Clusters	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	genes	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	coherent	_	ADJ	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	patterns	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	cultured	_	VERB	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	breast	_	NOUN	_	Number=Sing	_	_	_	_
15	tumors	_	NOUN	_	Number=Plur	_	_	_	_
16	samples	_	NOUN	_	Number=Plur	_	_	_	_
17	could	_	AUX	_	VerbForm=Fin	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	related	_	ADJ	_	Degree=Pos	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	specific	_	ADJ	_	Degree=Pos	_	_	_	_
22	features	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	biological	_	ADJ	_	Degree=Pos	_	_	_	_
25	variation	_	NOUN	_	Number=Sing	_	_	_	_
26	among	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	samples	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	such	_	ADJ	_	Degree=Pos	_	_	_	_
3	clusters	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	have	_	VERB	_	VerbForm=Inf	_	_	_	_
8	patterns	_	NOUN	_	Number=Plur	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	correlated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	variation	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
16	rates	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	IFN	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	signal	_	NOUN	_	Number=Sing	_	_	_	_
26	transduction	_	NOUN	_	Number=Sing	_	_	_	_
27	pathway	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	respectively	_	ADV	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Clusters	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	genes	_	NOUN	_	Number=Plur	_	_	_	_
4	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	stromal	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	breast	_	NOUN	_	Number=Sing	_	_	_	_
13	tumors	_	NOUN	_	Number=Plur	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	analysis	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	feasibility	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	usefulness	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	systematic	_	ADJ	_	Degree=Pos	_	_	_	_
11	approach	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	SCONJ	_	_	_	_	_	_
13	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
14	variation	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	patterns	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	cancers	_	NOUN	_	Number=Plur	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	means	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	dissect	_	VERB	_	VerbForm=Inf	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	classify	_	VERB	_	VerbForm=Inf	_	_	_	_
29	solid	_	ADJ	_	Degree=Pos	_	_	_	_
30	tumors	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011626	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	correlate	_	VERB	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	syncytium	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
12	capacity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	8e51	_	NUM	_	NumType=Card	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	defective	_	ADJ	_	Degree=Pos	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	virus	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	double	_	ADJ	_	Degree=Pos	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	LTR	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
15	virus	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	HIV	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
25	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
31	viral	_	ADJ	_	Degree=Pos	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	present	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	characterisation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	subunits	_	NOUN	_	Number=Plur	_	_	_	_
13	engaged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	complexes	_	NOUN	_	Number=Plur	_	_	_	_
16	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	HIV	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	8e51	_	NUM	_	Number=Sing	_	_	_	_
29	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	that	_	PRON	_	PronType=Rel	_	_	_	_
32	harbour	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	defective	_	ADJ	_	Degree=Pos	_	_	_	_
35	HIV	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADV	_	_	_	_	_	_
2	least	_	ADV	_	Degree=Sup	_	_	_	_
3	four	_	NUM	_	NumType=Card	_	_	_	_
4	different	_	ADJ	_	Degree=Pos	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	NF	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	complexes	_	NOUN	_	Number=Plur	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	present	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	With	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	use	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	composition	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	each	_	DET	_	_	_	_	_	_
14	complex	_	NOUN	_	Number=Sing	_	_	_	_
15	using	_	VERB	_	VerbForm=Ger	_	_	_	_
16	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
17	mobility	_	NOUN	_	Number=Sing	_	_	_	_
18	shift	_	NOUN	_	Number=Sing	_	_	_	_
19	assays	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	presence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	several	_	ADJ	_	Degree=Pos	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	family	_	NOUN	_	Number=Sing	_	_	_	_
12	members	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	with	_	SCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transactivating	_	NOUN	_	Number=Sing	_	_	_	_
17	RelA	_	NOUN	_	Number=Sing	_	_	_	_
18	being	_	AUX	_	VerbForm=Ger	_	_	_	_
19	engaged	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
22	complexes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	importance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	complexes	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	viral	_	ADJ	_	Degree=Pos	_	_	_	_
10	functions	_	NOUN	_	Number=Plur	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	established	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	comparing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	level	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	DNA	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	complexes	_	NOUN	_	Number=Plur	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	syncytia	_	ADJ	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	8e51	_	NUM	_	NumType=Card	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	fact	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	8e51	_	NUM	_	NumType=Card	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	almost	_	ADV	_	_	_	_	_	_
9	lost	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	syncytia	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
14	capacity	_	NOUN	_	Number=Sing	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
19	at	_	ADV	_	_	_	_	_	_
20	least	_	ADV	_	Degree=Sup	_	_	_	_
21	10	_	NUM	_	NumType=Card	_	_	_	_
22	times	_	NOUN	_	Number=Plur	_	_	_	_
23	less	_	ADV	_	Degree=Cmp	_	_	_	_
24	active	_	ADJ	_	Degree=Pos	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	DNA	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	binding	_	VERB	_	Number=Sing	_	_	_	_
31	complex	_	NOUN	_	Number=Sing	_	_	_	_
32	than	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	actively	_	ADV	_	_	_	_	_	_
35	fusing	_	VERB	_	VerbForm=Ger	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	correlation	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	level	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	at	_	ADV	_	_	_	_	_	_
10	least	_	ADV	_	Degree=Sup	_	_	_	_
11	three	_	NUM	_	NumType=Card	_	_	_	_
12	other	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	change	_	VERB	_	VerbForm=Inf	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011633	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	triplex	_	NOUN	_	Number=Sing	_	_	_	_
3	formation	_	NOUN	_	Number=Sing	_	_	_	_
4	selectively	_	ADV	_	_	_	_	_	_
5	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
9	colony	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
4	colony	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	GM	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	CSF	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	hemopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
16	growth	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	GM	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	CSF	_	PROPN	_	Number=Sing	_	_	_	_
5	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	appear	_	VERB	_	VerbForm=Inf	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	essential	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	normal	_	ADJ	_	Degree=Pos	_	_	_	_
13	hemopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	GM	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	CSF	_	PROPN	_	Number=Sing	_	_	_	_
20	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
22	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	some	_	DET	_	_	_	_	_	_
28	diseases	_	NOUN	_	Number=Plur	_	_	_	_
29	such	_	ADJ	_	Degree=Pos	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
32	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
35	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	Rel	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	within	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	GM	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	CSF	_	NOUN	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	termed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	element	_	NOUN	_	Number=Sing	_	_	_	_
20	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	important	_	ADJ	_	Degree=Pos	_	_	_	_
24	for	_	SCONJ	_	_	_	_	_	_
25	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	reporter	_	NOUN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	assays	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	response	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	number	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	T	_	PROPN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	oligonucleotide	_	ADV	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	triple	_	ADJ	_	Number=Sing	_	_	_	_
7	helix	_	NOUN	_	Number=Sing	_	_	_	_
8	formation	_	NOUN	_	Number=Sing	_	_	_	_
9	across	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	sequence	_	NOUN	_	Number=Sing	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	potential	_	ADJ	_	Degree=Pos	_	_	_	_
16	tool	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
19	GM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	CSF	_	NOUN	_	Number=Sing	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	15	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	base	_	NOUN	_	Number=Sing	_	_	_	_
5	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	GM3	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	targeted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	purine	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	rich	_	ADJ	_	Degree=Pos	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	GM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	CSF	_	NOUN	_	Number=Sing	_	_	_	_
22	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	overlaps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
29	element	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	DNase	_	PROPN	_	Number=Sing	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	footprinting	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	GM3	_	PROPN	_	Number=Sing	_	_	_	_
12	formed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	collinear	_	NOUN	_	Number=Sing	_	_	_	_
18	triplex	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	double	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	DNA	_	NOUN	_	Number=Sing	_	_	_	_
25	target	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Triplex	_	ADJ	_	Number=Sing	_	_	_	_
2	formation	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	GM3	_	PROPN	_	Number=Sing	_	_	_	_
5	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	recombinant	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	GM	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	CSF	_	NOUN	_	Number=Sing	_	_	_	_
19	element	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	GM3	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	selective	_	ADJ	_	Degree=Pos	_	_	_	_
5	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
10	lymphotrophic	_	ADJ	_	Degree=Pos	_	_	_	_
11	virus	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	reporter	_	NOUN	_	Number=Sing	_	_	_	_
10	construct	_	NOUN	_	Number=Sing	_	_	_	_
11	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	GM	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	CSF	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	GM3	_	PROPN	_	Number=Sing	_	_	_	_
4	greatly	_	ADV	_	_	_	_	_	_
5	reduced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	concentration	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
10	GM	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	CSF	_	PROPN	_	Number=Sing	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	different	_	ADJ	_	Degree=Pos	_	_	_	_
17	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
26	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
27	3	_	NUM	_	NumType=Card	_	_	_	_
28	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
29	levels	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	same	_	ADJ	_	Degree=Pos	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	element	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	GM	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	CSF	_	PROPN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	central	_	ADJ	_	Degree=Pos	_	_	_	_
16	role	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
24	GM	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	CSF	_	PROPN	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Colinear	_	ADJ	_	Degree=Pos	_	_	_	_
2	triplex	_	NOUN	_	Number=Sing	_	_	_	_
3	formation	_	NOUN	_	Number=Sing	_	_	_	_
4	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	selective	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	repressor	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	GM	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	CSF	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	have	_	VERB	_	VerbForm=Inf	_	_	_	_
19	potential	_	ADJ	_	Degree=Pos	_	_	_	_
20	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
21	application	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	cases	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	undesirable	_	ADJ	_	Degree=Pos	_	_	_	_
26	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011637	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Association	_	NOUN	_	Number=Sing	_	_	_	_
2	between	_	ADP	_	_	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
6	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
7	molecule	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	integration	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	adult	_	NOUN	_	Number=Sing	_	_	_	_
22	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
23	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
11	molecule	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	adult	_	NOUN	_	Number=Sing	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	ATL	_	NOUN	_	_	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	high	_	ADJ	_	Degree=Pos	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	whereas	_	SCONJ	_	_	_	_	_	_
32	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	T-lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
37	not	_	PART	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	influence	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	molecules	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
18	blot	_	NOUN	_	Number=Sing	_	_	_	_
19	analysis	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	measure	_	VERB	_	VerbForm=Inf	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	level	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	Southern	_	ADJ	_	Degree=Pos	_	_	_	_
32	blot	_	NOUN	_	Number=Sing	_	_	_	_
33	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	integration	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	human	_	ADJ	_	Degree=Pos	_	_	_	_
40	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
43	virus	_	NOUN	_	Number=Sing	_	_	_	_
44	type	_	NOUN	_	Number=Sing	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	1	_	NUM	_	NumType=Card	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	provirus	_	NOUN	_	Number=Sing	_	_	_	_
52	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
53	done	_	VERB	_	Degree=Pos	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	ATL	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	generally	_	ADV	_	_	_	_	_	_
14	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
15	than	_	ADP	_	_	_	_	_	_
16	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	T-lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	ILT	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	mat	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	ATL16T	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	-)	_	PUNCT	_	_	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	although	_	SCONJ	_	_	_	_	_	_
14	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	ATL	_	PROPN	_	_	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	rather	_	ADV	_	_	_	_	_	_
21	low	_	ADJ	_	Degree=Pos	_	_	_	_
22	surface	_	NOUN	_	Number=Sing	_	_	_	_
23	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Southern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	only	_	ADV	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	four	_	NUM	_	NumType=Card	_	_	_	_
10	bands	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	ILT	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	mat	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	ATL16T	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	respectively	_	ADV	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	whereas	_	ADV	_	_	_	_	_	_
27	>	_	PUNCT	_	_	_	_	_	_

1	10	_	NUM	_	NumType=Card	_	_	_	_
2	bands	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	ATL	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
6	integration	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	provirus	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	genome	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	especially	_	ADV	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	number	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	integration	_	NOUN	_	Number=Sing	_	_	_	_
24	sites	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	one	_	NUM	_	NumType=Card	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	factors	_	NOUN	_	Number=Plur	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	induction	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	molecules	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011642	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_

1	B	_	X	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	Rel	_	VERB	_	Number=Sing	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
9	blood	_	NOUN	_	Number=Sing	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	anti-HLA	_	ADJ	_	Number=Sing	_	_	_	_
14	class	_	NOUN	_	Number=Sing	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
17	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
2	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
3	against	_	ADP	_	_	_	_	_	_
4	either	_	CCONJ	_	_	_	_	_	_
5	monomorphic	_	ADJ	_	Degree=Pos	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	polymorphic	_	ADJ	_	Degree=Pos	_	_	_	_
8	determinants	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	class	_	NOUN	_	Number=Sing	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	antigen	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	highly	_	ADV	_	_	_	_	_	_
18	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	lymphocytes	_	VERB	_	Number=Plur	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	Rel	_	NOUN	_	Number=Sing	_	_	_	_
31	complexes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
2	included	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	both	_	CCONJ	_	_	_	_	_	_
4	p50/p50	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	p50/p65	_	NUM	_	Number=Sing	_	_	_	_
7	dimers	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	recognized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	complexes	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	extracts	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	incubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	anti-class	_	NOUN	_	Number=Sing	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
15	antibody	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	mAb	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	1.5	_	NUM	_	NumType=Card	_	_	_	_
21	h	_	NOUN	_	NumType=Card	_	_	_	_
22	;	_	PUNCT	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	induction	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
27	at	_	ADP	_	_	_	_	_	_
28	5	_	NUM	_	NumType=Card	_	_	_	_
29	h	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
32	at	_	ADP	_	_	_	_	_	_
33	16	_	NUM	_	NumType=Card	_	_	_	_
34	h	_	NOUN	_	Number=Plur	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	no	_	ADV	_	_	_	_	_	_
37	longer	_	ADV	_	Degree=Cmp	_	_	_	_
38	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
39	at	_	ADP	_	_	_	_	_	_
40	40	_	NUM	_	NumType=Card	_	_	_	_
41	h	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mAb	_	NOUN	_	Number=Sing	_	_	_	_
3	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	X	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	Rel	_	VERB	_	Number=Sing	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	incubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	presence	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	3,4	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dichloroisocoumarin	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	kappa	_	VERB	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	degradation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
7	class	_	NOUN	_	Number=Sing	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	triggering	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	ADP	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	Rel	_	VERB	_	Number=Sing	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
8	blood	_	NOUN	_	Number=Sing	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	thereby	_	ADV	_	_	_	_	_	_
13	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011650	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	12	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NK	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	absence	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	early	_	ADJ	_	Degree=Pos	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	responses	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	12	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
15	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
21	production	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	only	_	ADV	_	_	_	_	_	_
25	partially	_	ADV	_	_	_	_	_	_
26	overlapping	_	VERB	_	Degree=Pos	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	may	_	AUX	_	VerbForm=Fin	_	_	_	_
30	depend	_	VERB	_	VerbForm=Inf	_	_	_	_
31	on	_	ADP	_	_	_	_	_	_
32	induced	_	VERB	_	Degree=Pos	_	_	_	_
33	differential	_	ADJ	_	Degree=Pos	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	specific	_	ADJ	_	Degree=Pos	_	_	_	_
37	sets	_	NOUN	_	Number=Plur	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	genes	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	reverse	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	PCR	_	NOUN	_	Number=Sing	_	_	_	_
6	differential	_	NOUN	_	Number=Sing	_	_	_	_
7	display	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	isolated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
13	species	_	NOUN	_	Number=Plur	_	_	_	_
14	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	not	_	ADV	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	12	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	NK	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
7	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	egr	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	fast	_	ADJ	_	Degree=Pos	_	_	_	_
20	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	NK	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	upon	_	ADP	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	but	_	CCONJ	_	_	_	_	_	_
32	not	_	ADV	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	12	_	NUM	_	NumType=Card	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	encoding	_	VERB	_	Number=Sing	_	_	_	_
9	members	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	AP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	family	_	NOUN	_	Number=Sing	_	_	_	_
18	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	junB	_	NOUN	_	Number=Sing	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	also	_	ADV	_	_	_	_	_	_
25	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	upon	_	ADP	_	_	_	_	_	_
27	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	NK	_	PROPN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	T	_	PROPN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	but	_	CCONJ	_	_	_	_	_	_
39	not	_	ADV	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	12	_	NUM	_	NumType=Card	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	whereas	_	SCONJ	_	_	_	_	_	_
45	expression	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	c	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	jun	_	NOUN	_	Number=Sing	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	junD	_	NOUN	_	Number=Sing	_	_	_	_
52	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
53	not	_	PART	_	_	_	_	_	_
54	modified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
55	by	_	ADP	_	_	_	_	_	_
56	either	_	CCONJ	_	_	_	_	_	_
57	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Accordingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	DNA	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	AP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	exclusively	_	ADV	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
14	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	both	_	CCONJ	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	12	_	NUM	_	NumType=Card	_	_	_	_
24	induce	_	VERB	_	_	_	_	_	_
25	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
26	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
27	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	NK	_	PROPN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	T	_	PROPN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	whereas	_	ADV	_	_	_	_	_	_
35	only	_	ADV	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	induces	_	VERB	_	Number=Plur	_	_	_	_
40	bcl	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	2	_	NUM	_	NumType=Card	_	_	_	_
43	expression	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	demonstration	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	12	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	mediated	_	VERB	_	Degree=Pos	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	NK	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	members	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	early	_	ADJ	_	Degree=Pos	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	genes	_	NOUN	_	Number=Plur	_	_	_	_
32	family	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	egr	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	junB	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	AP	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
48	activity	_	NOUN	_	Number=Sing	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	or	_	CCONJ	_	_	_	_	_	_
51	bcl	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	2	_	NUM	_	NumType=Card	_	_	_	_
54	expression	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	functional	_	ADJ	_	Degree=Pos	_	_	_	_
5	differences	_	NOUN	_	Number=Plur	_	_	_	_
6	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	12	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	may	_	AUX	_	VerbForm=Fin	_	_	_	_
20	depend	_	VERB	_	VerbForm=Inf	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	at	_	ADV	_	_	_	_	_	_
23	least	_	ADV	_	Degree=Sup	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	part	_	ADJ	_	Degree=Pos	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	differential	_	ADJ	_	Degree=Pos	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	regulation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011652	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	early	_	ADJ	_	Degree=Pos	_	_	_	_
7	stages	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
5	sets	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	genes	_	NOUN	_	Number=Plur	_	_	_	_
8	at	_	ADP	_	_	_	_	_	_
9	different	_	ADJ	_	Degree=Pos	_	_	_	_
10	stages	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	T-lymphocyte	_	ADJ	_	Number=Sing	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	level	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	number	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	recent	_	ADJ	_	Degree=Pos	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	interactions	_	NOUN	_	Number=Plur	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	new	_	ADJ	_	Degree=Pos	_	_	_	_
17	insights	_	NOUN	_	Number=Plur	_	_	_	_
18	into	_	ADP	_	_	_	_	_	_
19	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
20	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	assembly	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
8	order	_	NOUN	_	Number=Sing	_	_	_	_
9	nucleoprotein	_	NOUN	_	Number=Sing	_	_	_	_
10	complexes	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	other	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	interactions	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	enhance	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	functional	_	ADJ	_	Degree=Pos	_	_	_	_
21	specificity	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
24	regulators	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011659	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Oleic	_	ADJ	_	Number=Sing	_	_	_	_
2	acid	_	ADJ	_	Number=Sing	_	_	_	_
3	inhibits	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	:	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	direct	_	ADJ	_	Degree=Pos	_	_	_	_
3	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
4	antiatherogenic	_	ADJ	_	Number=Sing	_	_	_	_
5	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	nutritional	_	ADJ	_	Degree=Pos	_	_	_	_
9	component	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	mediterranean	_	ADJ	_	Degree=Pos	_	_	_	_
13	diet	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	oleic	_	ADJ	_	Number=Sing	_	_	_	_
3	acid	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	antiatherogenic	_	ADJ	_	Degree=Pos	_	_	_	_
9	effects	_	NOUN	_	Number=Plur	_	_	_	_
10	attributed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	Mediterranean	_	ADJ	_	Degree=Pos	_	_	_	_
14	diet	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	whether	_	SCONJ	_	_	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	fatty	_	NOUN	_	Number=Sing	_	_	_	_
21	acid	_	NOUN	_	Number=Sing	_	_	_	_
22	can	_	AUX	_	VerbForm=Fin	_	_	_	_
23	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
24	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	ie	_	X	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	concerted	_	ADJ	_	Degree=Pos	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	products	_	NOUN	_	Number=Plur	_	_	_	_
35	involved	_	ADJ	_	Degree=Pos	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	leukocyte	_	ADJ	_	Degree=Pos	_	_	_	_
38	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	early	_	ADJ	_	Degree=Pos	_	_	_	_
41	atherogenesis	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	incubated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	sodium	_	NOUN	_	Number=Sing	_	_	_	_
4	oleate	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
8	vein	_	NOUN	_	Number=Sing	_	_	_	_
9	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	0	_	NUM	_	NumType=Card	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	72	_	NUM	_	NumType=Card	_	_	_	_
15	hours	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	coincubation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	oleate	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
25	tumor	_	NOUN	_	Number=Sing	_	_	_	_
26	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1beta	_	PROPN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	4	_	NUM	_	NumType=Card	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	Escherichia	_	PROPN	_	Number=Sing	_	_	_	_
45	coli	_	NOUN	_	Number=Sing	_	_	_	_
46	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	LPS	_	NOUN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	or	_	CCONJ	_	_	_	_	_	_
52	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
53	12	_	NUM	_	NumType=Card	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	myristate	_	NOUN	_	Number=Sing	_	_	_	_
56	13	_	NUM	_	NumType=Card	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	acetate	_	NOUN	_	Number=Sing	_	_	_	_
59	for	_	ADP	_	_	_	_	_	_
60	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
61	further	_	ADJ	_	Degree=Cmp	_	_	_	_
62	6	_	NUM	_	NumType=Card	_	_	_	_
63	to	_	ADP	_	_	_	_	_	_
64	24	_	NUM	_	NumType=Card	_	_	_	_
65	hours	_	NOUN	_	Number=Plur	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
8	molecule	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	E-selectin	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
21	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
22	molecule	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	monitored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	surface	_	NOUN	_	Number=Sing	_	_	_	_
30	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
31	immunoassays	_	NOUN	_	Number=Plur	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	flow	_	NOUN	_	Number=Sing	_	_	_	_
34	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	steady	_	ADJ	_	Degree=Pos	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	state	_	NOUN	_	Number=Sing	_	_	_	_
40	levels	_	NOUN	_	Number=Plur	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
46	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
47	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	by	_	ADP	_	_	_	_	_	_
49	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
50	blot	_	NOUN	_	Number=Sing	_	_	_	_
51	analysis	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	10	_	NUM	_	NumType=Card	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	100	_	NUM	_	NumType=Card	_	_	_	_
5	micromol	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	L	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	>	_	SYM	_	_	_	_	_	_
10	24	_	NUM	_	NumType=Card	_	_	_	_
11	hours	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	oleate	_	NOUN	_	Number=Sing	_	_	_	_
14	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	all	_	DET	_	_	_	_	_	_
19	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
20	molecules	_	NOUN	_	Number=Plur	_	_	_	_
21	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	72	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	hour	_	NOUN	_	Number=Sing	_	_	_	_
6	incubation	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	oleate	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	further	_	ADJ	_	Degree=Pos	_	_	_	_
12	16	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	hour	_	NOUN	_	Number=Sing	_	_	_	_
15	incubation	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	oleate	_	NOUN	_	Number=Sing	_	_	_	_
18	plus	_	CCONJ	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	microg	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	mL	_	NOUN	_	Number=Sing	_	_	_	_
23	LPS	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	>	_	SYM	_	_	_	_	_	_
33	40	_	NUM	_	NumType=Card	_	_	_	_
34	%	_	SYM	_	Number=Sing	_	_	_	_
35	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	control	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Adhesion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	monocytoid	_	ADJ	_	Degree=Pos	_	_	_	_
4	U937	_	NUM	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	LPS	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	concomitantly	_	ADV	_	_	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Oleate	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	quantitatively	_	ADV	_	_	_	_	_	_
6	similar	_	ADJ	_	Degree=Pos	_	_	_	_
7	reduction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
13	levels	_	NOUN	_	Number=Plur	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
16	blot	_	NOUN	_	Number=Sing	_	_	_	_
17	analysis	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
27	mobility	_	NOUN	_	Number=Sing	_	_	_	_
28	shift	_	NOUN	_	Number=Sing	_	_	_	_
29	assays	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Incubation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	oleate	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	72	_	NUM	_	NumType=Card	_	_	_	_
9	hours	_	NOUN	_	Number=Plur	_	_	_	_
10	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	relative	_	ADJ	_	Degree=Pos	_	_	_	_
13	proportions	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	saturated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	palmitic	_	ADJ	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	stearic	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	acids	_	VERB	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	total	_	ADJ	_	Degree=Pos	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	lipids	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	proportions	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	oleate	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	total	_	ADJ	_	Degree=Pos	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	lipids	_	NOUN	_	Number=Plur	_	_	_	_
36	without	_	SCONJ	_	_	_	_	_	_
37	significantly	_	ADV	_	_	_	_	_	_
38	changing	_	VERB	_	VerbForm=Ger	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	relative	_	ADJ	_	Degree=Pos	_	_	_	_
41	proportions	_	NOUN	_	Number=Plur	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	polyunsaturated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
44	fatty	_	NOUN	_	Number=Sing	_	_	_	_
45	acids	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	less	_	ADV	_	Degree=Cmp	_	_	_	_
3	potent	_	ADJ	_	Degree=Pos	_	_	_	_
4	than	_	ADP	_	_	_	_	_	_
5	polyunsaturated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	fatty	_	NOUN	_	Number=Sing	_	_	_	_
7	acids	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
10	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	oleic	_	ADJ	_	Number=Sing	_	_	_	_
14	acid	_	NOUN	_	Number=Sing	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	prevention	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	atherogenesis	_	NOUN	_	Number=Sing	_	_	_	_
22	through	_	ADP	_	_	_	_	_	_
23	selective	_	ADJ	_	Degree=Pos	_	_	_	_
24	displacement	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	saturated	_	VERB	_	Degree=Pos	_	_	_	_
27	fatty	_	NOUN	_	Number=Sing	_	_	_	_
28	acids	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	membrane	_	NOUN	_	Number=Sing	_	_	_	_
32	phospholipids	_	NOUN	_	Number=Plur	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	consequent	_	ADJ	_	Degree=Pos	_	_	_	_
36	modulation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	for	_	ADP	_	_	_	_	_	_
41	molecules	_	NOUN	_	Number=Plur	_	_	_	_
42	involved	_	ADJ	_	Degree=Pos	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	monocyte	_	ADJ	_	Degree=Pos	_	_	_	_
45	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011660	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	zeta	_	NOUN	_	Number=Sing	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	globin	_	NOUN	_	Number=Sing	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	alpha	_	PROPN	_	Number=Sing	_	_	_	_
12	globin	_	PROPN	_	Number=Sing	_	_	_	_
13	regulatory	_	ADJ	_	Number=Sing	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	HS	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	40	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	:	_	PUNCT	_	_	_	_	_	_
21	functional	_	ADJ	_	Degree=Pos	_	_	_	_
22	role	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	DNA	_	NOUN	_	Number=Sing	_	_	_	_
29	complexes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	functional	_	ADJ	_	Degree=Pos	_	_	_	_
5	interaction	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
9	zeta	_	NOUN	_	Number=Sing	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	globin	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	alpha	_	PROPN	_	Number=Sing	_	_	_	_
16	globin	_	PROPN	_	Number=Sing	_	_	_	_
17	regulatory	_	ADJ	_	Number=Sing	_	_	_	_
18	element	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	HS	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	40	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	40	_	NUM	_	NumType=Card	_	_	_	_
26	kb	_	NOUN	_	Number=Sing	_	_	_	_
27	upstream	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	zeta	_	NOUN	_	Number=Sing	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	globin	_	NOUN	_	Degree=Pos	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	transient	_	ADJ	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	assay	_	VERB	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	HS	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	40	_	NUM	_	NumType=Card	_	_	_	_
12	behaved	_	ADJ	_	Degree=Pos	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	authentic	_	ADJ	_	Degree=Pos	_	_	_	_
16	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	high	_	ADJ	_	Degree=Pos	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	zeta	_	NOUN	_	Number=Sing	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	globin	_	NOUN	_	Degree=Pos	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	K562	_	NUM	_	NumType=Card	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	line	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	/	_	PUNCT	_	_	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	fetal	_	ADJ	_	Number=Sing	_	_	_	_
40	origin	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	sequences	_	NOUN	_	Number=Plur	_	_	_	_
3	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	-	_	SYM	_	_	_	_	_	_
6	559	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	-	_	SYM	_	_	_	_	_	_
9	88	_	NUM	_	NumType=Card	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	zeta	_	NOUN	_	Number=Sing	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	globin	_	NOUN	_	Degree=Pos	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	dispensable	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	enhancerless	_	ADJ	_	Degree=Pos	_	_	_	_
23	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	HS	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	40	_	NUM	_	NumType=Card	_	_	_	_
33	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	activity	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	zeta	_	NOUN	_	Number=Sing	_	_	_	_
40	2	_	NUM	_	NumType=Card	_	_	_	_
41	globin	_	NOUN	_	Degree=Pos	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Site	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	HS	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	40	_	NUM	_	NumType=Card	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	zeta	_	NOUN	_	Number=Sing	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	globin	_	NOUN	_	Degree=Pos	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	interaction	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	two	_	NUM	_	NumType=Card	_	_	_	_
23	GATA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	binding	_	VERB	_	Number=Sing	_	_	_	_
28	motifs	_	NOUN	_	Number=Plur	_	_	_	_
29	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	at	_	ADP	_	_	_	_	_	_
31	-	_	SYM	_	_	_	_	_	_
32	230	_	NUM	_	NumType=Card	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	-	_	SYM	_	_	_	_	_	_
35	104	_	NUM	_	NumType=Card	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	respectively	_	ADV	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	functional	_	ADJ	_	Degree=Pos	_	_	_	_
3	domains	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	HS	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	40	_	NUM	_	NumType=Card	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	mapped	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Bal	_	PROPN	_	Number=Sing	_	_	_	_
2	31	_	NUM	_	NumType=Card	_	_	_	_
3	deletion	_	NOUN	_	Number=Sing	_	_	_	_
4	mapping	_	NOUN	_	Number=Sing	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	one	_	NUM	_	NumType=Card	_	_	_	_
9	GATA	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	motif	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	one	_	NUM	_	NumType=Card	_	_	_	_
15	GT	_	NOUN	_	Number=Sing	_	_	_	_
16	motif	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	two	_	NUM	_	NumType=Card	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	E2	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	AP1	_	NOUN	_	Number=Sing	_	_	_	_
25	motifs	_	NOUN	_	Number=Plur	_	_	_	_
26	together	_	ADV	_	_	_	_	_	_
27	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	functional	_	ADJ	_	Degree=Pos	_	_	_	_
30	core	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	HS	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	SYM	_	_	_	_	_	_
34	40	_	NUM	_	NumType=Card	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	specific	_	ADJ	_	Degree=Pos	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	zeta	_	NOUN	_	Number=Sing	_	_	_	_
44	2	_	NUM	_	NumType=Card	_	_	_	_
45	globin	_	NOUN	_	Number=Sing	_	_	_	_
46	promoter	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Site	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
5	further	_	ADV	_	_	_	_	_	_
6	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
10	function	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	one	_	NUM	_	NumType=Card	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	E2	_	NUM	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	AP1	_	NOUN	_	Number=Sing	_	_	_	_
21	motifs	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	HS	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	40	_	NUM	_	NumType=Card	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	through	_	ADP	_	_	_	_	_	_
29	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	E2	_	PROPN	_	Number=Sing	_	_	_	_
35	but	_	CCONJ	_	_	_	_	_	_
36	not	_	ADV	_	_	_	_	_	_
37	AP1	_	NOUN	_	Number=Sing	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	factor	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	did	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
6	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	HS	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	40	_	NUM	_	NumType=Card	_	_	_	_
12	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	K562	_	NUM	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	adult	_	NOUN	_	Number=Sing	_	_	_	_
19	nucleated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	different	_	ADJ	_	Degree=Pos	_	_	_	_
24	nonerythroid	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	motifs	_	NOUN	_	Number=Plur	_	_	_	_
4	within	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	functional	_	ADJ	_	Degree=Pos	_	_	_	_
7	core	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HS	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	SYM	_	_	_	_	_	_
11	40	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	as	_	SCONJ	_	_	_	_	_	_
14	mapped	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	transient	_	ADJ	_	Degree=Pos	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	analysis	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	s	_	X	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	in	_	SCONJ	_	_	_	_	_	_
30	living	_	VERB	_	VerbForm=Ger	_	_	_	_
31	K562	_	NUM	_	NumType=Card	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	but	_	CCONJ	_	_	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	nonerythroid	_	ADJ	_	Degree=Pos	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	hand	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	only	_	ADV	_	_	_	_	_	_
7	one	_	NUM	_	NumType=Card	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	apparently	_	ADV	_	_	_	_	_	_
11	nonfunctional	_	ADJ	_	Degree=Pos	_	_	_	_
12	sequence	_	NOUN	_	Number=Sing	_	_	_	_
13	motifs	_	NOUN	_	Number=Plur	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	bound	_	ADJ	_	Degree=Pos	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	vivo	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	comparison	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	K562	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	nucleated	_	VERB	_	Degree=Pos	_	_	_	_
7	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	adult	_	ADJ	_	Degree=Pos	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	bone	_	NOUN	_	Number=Sing	_	_	_	_
12	marrow	_	NOUN	_	Number=Sing	_	_	_	_
13	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	similar	_	ADJ	_	Degree=Pos	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	nonidentical	_	ADJ	_	Degree=Pos	_	_	_	_
18	pattern	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	vivo	_	NOUN	_	Number=Sing	_	_	_	_
25	at	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	HS	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	40	_	NUM	_	NumType=Card	_	_	_	_
30	region	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	DET	_	_	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
10	zeta	_	NOUN	_	Number=Sing	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	globin	_	ADJ	_	Degree=Pos	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	fetal	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	adult	_	NOUN	_	Number=Sing	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	globin	_	NOUN	_	Degree=Pos	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	specific	_	ADJ	_	Degree=Pos	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
31	stage	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	specific	_	ADJ	_	Degree=Pos	_	_	_	_
34	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	DNA	_	NOUN	_	Number=Sing	_	_	_	_
38	complexes	_	NOUN	_	Number=Plur	_	_	_	_
39	which	_	PRON	_	PronType=Rel	_	_	_	_
40	form	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
41	at	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	HS	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	40	_	NUM	_	NumType=Card	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	globin	_	ADJ	_	Degree=Pos	_	_	_	_
52	promoters	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011668	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Neuronal	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	type	_	NOUN	_	Number=Sing	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	nitric	_	NOUN	_	Number=Sing	_	_	_	_
7	oxide	_	NOUN	_	Number=Sing	_	_	_	_
8	synthase	_	NOUN	_	Number=Sing	_	_	_	_
9	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	immunologic	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	II	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	nitric	_	ADJ	_	Number=Sing	_	_	_	_
21	oxide	_	NOUN	_	Number=Sing	_	_	_	_
22	synthase	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Nitric	_	PROPN	_	Number=Sing	_	_	_	_
2	oxide	_	NOUN	_	Number=Sing	_	_	_	_
3	subserves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
5	physiologic	_	ADJ	_	Degree=Pos	_	_	_	_
6	roles	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
10	system	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	NO	_	DET	_	_	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	at	_	ADV	_	_	_	_	_	_
6	least	_	ADV	_	Degree=Sup	_	_	_	_
7	three	_	NUM	_	NumType=Card	_	_	_	_
8	different	_	ADJ	_	Degree=Pos	_	_	_	_
9	NO	_	DET	_	_	_	_	_	_
10	synthase	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	NOS	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	neuronal	_	ADJ	_	Degree=Pos	_	_	_	_
17	NOS	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	nNOS	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	endothelial	_	NOUN	_	Number=Sing	_	_	_	_
23	NOS	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	immunologic	_	ADJ	_	Degree=Pos	_	_	_	_
27	NOS	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	iNOS	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	nNOS	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	predominant	_	ADJ	_	Degree=Pos	_	_	_	_
8	isoform	_	NOUN	_	Number=Sing	_	_	_	_
9	constitutively	_	ADV	_	_	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	glia	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	NO	_	ADV	_	_	_	_	_	_
2	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	nNOS	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	glia	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	NOS	_	PROPN	_	Number=Sing	_	_	_	_
20	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
21	enhance	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	basal	_	ADJ	_	Number=Sing	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Pyrrolidine	_	PROPN	_	Number=Sing	_	_	_	_
2	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	most	_	ADJ	_	Degree=Sup	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	;	_	PUNCT	_	_	_	_	_	_
16	however	_	ADV	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	also	_	ADV	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	potent	_	ADJ	_	Degree=Pos	_	_	_	_
26	scavenger	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	NO	_	DET	_	_	_	_	_	_
29	through	_	ADP	_	_	_	_	_	_
30	formation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	mononitrosyl	_	ADJ	_	Degree=Pos	_	_	_	_
33	iron	_	NOUN	_	Number=Sing	_	_	_	_
34	complexes	_	NOUN	_	Number=Plur	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	PDTC	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	tumor	_	NOUN	_	Number=Sing	_	_	_	_
13	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	TNF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Contrary	_	ADJ	_	Degree=Pos	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
10	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
13	tumor	_	NOUN	_	Number=Sing	_	_	_	_
14	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	astrocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	;	_	PUNCT	_	_	_	_	_	_
26	instead	_	ADV	_	_	_	_	_	_
27	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
28	itself	_	PRON	_	Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
29	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	astrocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
38	may	_	AUX	_	VerbForm=Fin	_	_	_	_
39	be	_	AUX	_	VerbForm=Inf	_	_	_	_
40	related	_	ADJ	_	Degree=Pos	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	scavenging	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	endogenously	_	ADV	_	_	_	_	_	_
45	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	NO	_	ADV	_	_	_	_	_	_
47	by	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
50	iron	_	NOUN	_	Number=Sing	_	_	_	_
51	complex	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	astrocytes	_	NOUN	_	Number=Sing	_	_	_	_
3	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	dramatically	_	ADV	_	_	_	_	_	_
6	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	iNOS	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	supporting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	physiologic	_	ADJ	_	Degree=Pos	_	_	_	_
19	relevance	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
22	NO	_	DET	_	_	_	_	_	_
23	regulation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	glia	_	NOUN	_	Number=Sing	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	mice	_	NOUN	_	Number=Plur	_	_	_	_
8	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
9	nNOS	_	NOUN	_	Number=Sing	_	_	_	_
10	responds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	more	_	ADV	_	_	_	_	_	_
12	rapidly	_	ADV	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	PDTC	_	NOUN	_	Number=Sing	_	_	_	_
15	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	astrocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	wild	_	ADJ	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	type	_	NOUN	_	Number=Sing	_	_	_	_
22	mice	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	nNOS	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	astrocytes	_	NOUN	_	Number=Sing	_	_	_	_
8	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	iNOS	_	ADJ	_	Degree=Pos	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	novel	_	NOUN	_	Number=Sing	_	_	_	_
20	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	nNOS	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	SCONJ	_	_	_	_	_	_
25	tonically	_	ADV	_	_	_	_	_	_
26	suppressing	_	VERB	_	VerbForm=Ger	_	_	_	_
27	central	_	ADJ	_	Degree=Pos	_	_	_	_
28	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
29	system	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	regulated	_	VERB	_	Degree=Pos	_	_	_	_
35	genes	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011669	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HIV	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	latency	_	NOUN	_	Number=Sing	_	_	_	_
7	reactivation	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	dehydroepiandrosterone	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	DHEA	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	analog	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	DHEA	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	initial	_	ADJ	_	Degree=Pos	_	_	_	_
3	infection	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	most	_	ADJ	_	Degree=Sup	_	_	_	_
17	individuals	_	NOUN	_	Number=Plur	_	_	_	_
18	usually	_	ADV	_	_	_	_	_	_
19	results	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	establishment	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	latent	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
28	infection	_	NOUN	_	Number=Sing	_	_	_	_
29	before	_	ADP	_	_	_	_	_	_
30	eventual	_	ADJ	_	Degree=Pos	_	_	_	_
31	progression	_	NOUN	_	Number=Sing	_	_	_	_
32	toward	_	ADP	_	_	_	_	_	_
33	acquired	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
35	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	can	_	AUX	_	VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	establish	_	VERB	_	VerbForm=Inf	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	latent	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
11	infection	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	some	_	DET	_	_	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	lines	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
20	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
21	virus	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	replication	_	NOUN	_	Number=Sing	_	_	_	_
16	can	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	antigens	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	tumor	_	NOUN	_	Number=Sing	_	_	_	_
28	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	[	_	PUNCT	_	_	_	_	_	_
32	TNF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	alpha	_	NOUN	_	Number=Sing	_	_	_	_
35	]	_	PUNCT	_	_	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	2	_	NUM	_	NumType=Card	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Various	_	ADJ	_	Degree=Pos	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	products	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	other	_	ADJ	_	Degree=Pos	_	_	_	_
6	viruses	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	HSV	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	EBV	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	CMV	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	HBV	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	HHV	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	6	_	X	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	can	_	AUX	_	VerbForm=Fin	_	_	_	_
26	also	_	ADV	_	_	_	_	_	_
27	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
28	HIV	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	long	_	ADJ	_	Degree=Pos	_	_	_	_
32	terminal	_	NOUN	_	Number=Sing	_	_	_	_
33	repeat	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	LTR	_	PROPN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	reporter	_	NOUN	_	Number=Sing	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	activity	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	basis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	observations	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
9	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	proposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	that	_	DET	_	_	_	_	_	_
13	reactivation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	latent	_	ADJ	_	Degree=Pos	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	harbored	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	chronically	_	ADV	_	_	_	_	_	_
22	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
30	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	important	_	ADJ	_	Degree=Pos	_	_	_	_
33	role	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	So	_	ADV	_	_	_	_	_	_
2	far	_	ADV	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	there	_	PRON	_	_	_	_	_	_
5	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	no	_	DET	_	_	_	_	_	_
7	drugs	_	NOUN	_	Number=Plur	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	therapy	_	NOUN	_	Number=Sing	_	_	_	_
10	available	_	ADJ	_	Degree=Pos	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
14	protection	_	NOUN	_	Number=Sing	_	_	_	_
15	against	_	ADP	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	latency	_	NOUN	_	Number=Sing	_	_	_	_
20	reactivation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	ACH	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	CEM	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	chronically	_	ADV	_	_	_	_	_	_
18	infected	_	VERB	_	Degree=Pos	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	low	_	ADJ	_	Degree=Pos	_	_	_	_
26	levels	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
29	virus	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	ACH	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	can	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	converted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	productive	_	ADJ	_	Degree=Pos	_	_	_	_
9	infection	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	13	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	acetate	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	TPA	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	TNF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	infection	_	NOUN	_	Number=Sing	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	HSV	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	ACH	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	line	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	good	_	ADJ	_	Degree=Pos	_	_	_	_
11	candidate	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	SCONJ	_	_	_	_	_	_
13	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	effects	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	drugs	_	NOUN	_	Number=Plur	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Previously	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	DHEA	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
10	analogs	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	DHEA	_	NOUN	_	Number=Sing	_	_	_	_
13	can	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	modest	_	ADJ	_	Degree=Pos	_	_	_	_
16	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	IIIB	_	NOUN	_	Number=Sing	_	_	_	_
22	replication	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
28	blood	_	NOUN	_	Number=Sing	_	_	_	_
29	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
30	cultures	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	0030011670	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	3q21	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	identification	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	intergenic	_	ADJ	_	Degree=Pos	_	_	_	_
12	fusion	_	NOUN	_	Number=Sing	_	_	_	_
13	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	ecotropic	_	ADJ	_	Degree=Pos	_	_	_	_
16	viral	_	ADJ	_	Degree=Pos	_	_	_	_
17	insertion	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	novel	_	NOUN	_	Degree=Pos	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	GR6	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
14	breakpoint	_	NOUN	_	Number=Sing	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	3q21	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	normally	_	ADV	_	_	_	_	_	_
22	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	early	_	ADJ	_	Degree=Pos	_	_	_	_
25	fetal	_	ADJ	_	Degree=Pos	_	_	_	_
26	development	_	NOUN	_	Number=Sing	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	adult	_	NOUN	_	Number=Sing	_	_	_	_
31	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
32	blood	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	GR6	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	UCSD	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	AML1	_	PROPN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
15	sample	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	both	_	DET	_	_	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Int	_	_	_	_
20	carry	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	t	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	;	_	PUNCT	_	_	_	_	_	_
26	3	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	q21	_	NUM	_	NumType=Card	_	_	_	_
30	;	_	PUNCT	_	_	_	_	_	_
31	q26	_	NUM	_	NumType=Card	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	UCSD	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	AML1	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	fusion	_	NOUN	_	Number=Sing	_	_	_	_
11	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
12	between	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	ecotropic	_	ADJ	_	Degree=Pos	_	_	_	_
15	viral	_	ADJ	_	Degree=Pos	_	_	_	_
16	insertion	_	NOUN	_	Number=Sing	_	_	_	_
17	site	_	NOUN	_	Number=Sing	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	EVI1	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	3q26	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	GR6	_	PROPN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	between	_	ADP	_	_	_	_	_	_
29	EVI1	_	PROPN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	Ribophorin	_	PROPN	_	Number=Sing	_	_	_	_
32	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
33	that	_	PRON	_	_	_	_	_	_
34	maps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	30	_	NUM	_	NumType=Card	_	_	_	_
36	kb	_	NOUN	_	Number=Sing	_	_	_	_
37	telomeric	_	NOUN	_	Number=Sing	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	GR6	_	PROPN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	3q21	_	NUM	_	NumType=Card	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	fusions	_	NOUN	_	Number=Plur	_	_	_	_
3	splice	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	'	_	PUNCT	_	_	_	_	_	_
7	ends	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	3q21	_	NUM	_	NumType=Card	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	into	_	ADP	_	_	_	_	_	_
13	exon	_	NOUN	_	Number=Sing	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	EVI1	_	PROPN	_	Degree=Pos	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	event	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	similar	_	ADJ	_	Degree=Pos	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	normal	_	ADJ	_	Degree=Pos	_	_	_	_
28	intergenic	_	ADJ	_	Degree=Pos	_	_	_	_
29	splicing	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	MDS1	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	EVI1	_	PROPN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
37	previously	_	ADV	_	_	_	_	_	_
38	documented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	leukemias	_	NOUN	_	Number=Plur	_	_	_	_
41	with	_	ADP	_	_	_	_	_	_
42	t	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	3	_	NUM	_	NumType=Card	_	_	_	_
45	;	_	PUNCT	_	_	_	_	_	_
46	21	_	NUM	_	NumType=Card	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	t	_	NOUN	_	Number=Sing	_	_	_	_
50	(	_	PUNCT	_	_	_	_	_	_
51	3	_	NUM	_	NumType=Card	_	_	_	_
52	;	_	PUNCT	_	_	_	_	_	_
53	12	_	NUM	_	NumType=Card	_	_	_	_
54	)	_	PUNCT	_	_	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	in	_	ADP	_	_	_	_	_	_
57	which	_	PRON	_	PronType=Rel	_	_	_	_
58	acute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
59	myelogenous	_	ADJ	_	Degree=Pos	_	_	_	_
60	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
61	1	_	NUM	_	NumType=Card	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	EVI1	_	NOUN	_	Number=Sing	_	_	_	_
64	fusions	_	NOUN	_	Number=Plur	_	_	_	_
65	and	_	CCONJ	_	_	_	_	_	_
66	ETV6	_	NOUN	_	Number=Sing	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	EVI1	_	NOUN	_	Number=Sing	_	_	_	_
69	fusions	_	NOUN	_	Number=Plur	_	_	_	_
70	,	_	PUNCT	_	_	_	_	_	_
71	respectively	_	ADV	_	_	_	_	_	_
72	,	_	PUNCT	_	_	_	_	_	_
73	occur	_	VERB	_	Number=Sing	_	_	_	_
74	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Ribophorin	_	PROPN	_	Number=Sing	_	_	_	_
3	I	_	PROPN	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	EVI1	_	PROPN	_	Number=Sing	_	_	_	_
6	fusion	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	particular	_	ADJ	_	Degree=Pos	_	_	_	_
9	may	_	AUX	_	VerbForm=Fin	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	common	_	ADJ	_	Degree=Pos	_	_	_	_
13	occurrence	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	t	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	3	_	NUM	_	NumType=Card	_	_	_	_
18	;	_	PUNCT	_	_	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011677	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Immortalization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CD4	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	CD8	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	+)	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
6	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	Tax	_	NOUN	_	Number=Sing	_	_	_	_
11	mutants	_	NOUN	_	Number=Plur	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	functional	_	ADJ	_	Degree=Pos	_	_	_	_
16	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
17	clone	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
4	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	trans	_	NOUN	_	Number=Plur	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	activator	_	NOUN	_	Number=Sing	_	_	_	_
17	Tax	_	NOUN	_	Number=Sing	_	_	_	_
18	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
20	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	have	_	VERB	_	VerbForm=Inf	_	_	_	_
23	transforming	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	culture	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	transgenic	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	mouse	_	NOUN	_	Number=Sing	_	_	_	_
33	models	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	viral	_	ADJ	_	Degree=Pos	_	_	_	_
9	long	_	ADJ	_	Degree=Pos	_	_	_	_
10	terminal	_	NOUN	_	Number=Sing	_	_	_	_
11	repeat	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	LTR	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	cyclic	_	ADJ	_	Degree=Pos	_	_	_	_
18	AMP	_	NOUN	_	Number=Sing	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	element	_	NOUN	_	Number=Sing	_	_	_	_
21	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	activating	_	NOUN	_	VerbForm=Ger	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	CREB	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	ATF	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	family	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	factors	_	NOUN	_	Number=Plur	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	Tax	_	NOUN	_	Number=Sing	_	_	_	_
38	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	expression	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
43	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
44	promoters	_	NOUN	_	Number=Plur	_	_	_	_
45	through	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	NF	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
50	pathway	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
53	activation	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Tax	_	NOUN	_	Number=Sing	_	_	_	_
3	mutants	_	NOUN	_	Number=Plur	_	_	_	_
4	M22	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	M47	_	PROPN	_	Number=Sing	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	previously	_	ADV	_	_	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	selectively	_	ADV	_	_	_	_	_	_
13	abrogate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	ability	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Tax	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	through	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	CREB	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	ATF	_	PROPN	_	Number=Sing	_	_	_	_
30	pathway	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	respectively	_	ADV	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	mutations	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	introduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	tax	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	ACH	_	PROPN	_	Number=Sing	_	_	_	_
12	functional	_	ADJ	_	Degree=Pos	_	_	_	_
13	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
14	clone	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	virus	_	NOUN	_	Number=Sing	_	_	_	_
22	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	mutant	_	NOUN	_	Number=Sing	_	_	_	_
26	ACH	_	NOUN	_	Number=Sing	_	_	_	_
27	clones	_	NOUN	_	Number=Plur	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	ability	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	immortalize	_	VERB	_	VerbForm=Inf	_	_	_	_
37	primary	_	ADJ	_	Degree=Pos	_	_	_	_
38	human	_	ADJ	_	Degree=Pos	_	_	_	_
39	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	virus	_	NOUN	_	Number=Sing	_	_	_	_
3	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	clone	_	NOUN	_	Number=Sing	_	_	_	_
7	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	M47	_	NOUN	_	Number=Sing	_	_	_	_
10	mutation	_	NOUN	_	Number=Sing	_	_	_	_
11	retained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	ability	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	immortalize	_	VERB	_	VerbForm=Inf	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	M22	_	PROPN	_	Number=Sing	_	_	_	_
21	mutant	_	NOUN	_	Number=Sing	_	_	_	_
22	lost	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	ability	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	immortalize	_	VERB	_	VerbForm=Inf	_	_	_	_
27	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	CREB	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	ATF	_	NOUN	_	Number=Sing	_	_	_	_
11	pathway	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	Tax	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	dispensable	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	whereas	_	SCONJ	_	_	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	pathway	_	NOUN	_	Number=Sing	_	_	_	_
35	may	_	AUX	_	VerbForm=Fin	_	_	_	_
36	be	_	AUX	_	VerbForm=Inf	_	_	_	_
37	critical	_	ADJ	_	Degree=Pos	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011679	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	long	_	ADJ	_	Degree=Pos	_	_	_	_
7	terminal	_	NOUN	_	Number=Sing	_	_	_	_
8	repeat	_	ADJ	_	Degree=Pos	_	_	_	_
9	quasispecies	_	NOUN	_	Number=Plur	_	_	_	_
10	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	basal	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	glial	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	generation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
5	diversity	_	NOUN	_	Number=Sing	_	_	_	_
6	during	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	course	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	infection	_	NOUN	_	Number=Sing	_	_	_	_
11	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	potential	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
16	all	_	DET	_	_	_	_	_	_
17	aspects	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	replication	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	including	_	VERB	_	VerbForm=Ger	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
29	genome	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	gain	_	VERB	_	VerbForm=Inf	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	better	_	ADJ	_	Degree=Cmp	_	_	_	_
5	understanding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	impact	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	long	_	ADJ	_	Degree=Pos	_	_	_	_
11	terminal	_	NOUN	_	Number=Sing	_	_	_	_
12	repeat	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	LTR	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	sequence	_	NOUN	_	Number=Sing	_	_	_	_
17	diversity	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	LTR	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	central	_	ADJ	_	Degree=Pos	_	_	_	_
29	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
30	system	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	CNS	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	immune	_	ADJ	_	Degree=Pos	_	_	_	_
36	system	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
39	amplified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
43	from	_	ADP	_	_	_	_	_	_
44	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
45	DNA	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	HIV	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	1	_	NUM	_	NumType=Card	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
52	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
53	blood	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Sequence	_	NOUN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	nineteen	_	NUM	_	NumType=Card	_	_	_	_
5	LTRs	_	PROPN	_	Number=Plur	_	_	_	_
6	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	adult	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	pediatric	_	ADJ	_	Degree=Pos	_	_	_	_
13	patients	_	NOUN	_	Number=Plur	_	_	_	_
14	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	average	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	33	_	NUM	_	NumType=Card	_	_	_	_
19	nucleotide	_	NOUN	_	Degree=Pos	_	_	_	_
20	changes	_	NOUN	_	Number=Plur	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	respect	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	sequence	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	LAI	_	PROPN	_	Number=Sing	_	_	_	_
30	LTR	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	within	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	455	_	NUM	_	NumType=Card	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	bp	_	PROPN	_	Number=Sing	_	_	_	_
37	U3	_	PROPN	_	Number=Sing	_	_	_	_
38	region	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	analyses	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	neuroglial	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	origin	_	NOUN	_	Number=Sing	_	_	_	_
11	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	some	_	DET	_	_	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
16	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
17	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	activities	_	NOUN	_	Number=Plur	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	varied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	significantly	_	ADV	_	_	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	LAI	_	PROPN	_	Number=Sing	_	_	_	_
25	LTR	_	PROPN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	U-373	_	NUM	_	Number=Sing	_	_	_	_
28	MG	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	astrocytoma	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	line	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	as	_	ADV	_	_	_	_	_	_
37	well	_	ADV	_	Degree=Pos	_	_	_	_
38	as	_	ADP	_	_	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	CD4	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	positive	_	ADJ	_	Degree=Pos	_	_	_	_
47	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
48	cell	_	NOUN	_	Number=Sing	_	_	_	_
49	line	_	NOUN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
3	which	_	PRON	_	PronType=Rel	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	highest	_	ADJ	_	Degree=Sup	_	_	_	_
7	activities	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	U	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	373	_	NUM	_	NumType=Card	_	_	_	_
12	MG	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	yielded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	high	_	ADJ	_	Degree=Pos	_	_	_	_
17	activities	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	generally	_	ADV	_	_	_	_	_	_
26	more	_	ADV	_	_	_	_	_	_
27	active	_	ADJ	_	Degree=Pos	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	when	_	ADV	_	PronType=Int	_	_	_	_
32	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	LAI	_	PROPN	_	Number=Sing	_	_	_	_
36	LTR	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Differences	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	LTR	_	PROPN	_	Number=Sing	_	_	_	_
4	sequence	_	NOUN	_	Number=Sing	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	differences	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	cis	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	sites	_	NOUN	_	Number=Plur	_	_	_	_
18	within	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	U3	_	PROPN	_	Number=Sing	_	_	_	_
21	region	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	LTR	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	as	_	SCONJ	_	_	_	_	_	_
27	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
30	mobility	_	NOUN	_	Number=Sing	_	_	_	_
31	shift	_	NOUN	_	Number=Sing	_	_	_	_
32	assays	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	particular	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	naturally	_	ADV	_	_	_	_	_	_
5	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	variation	_	NOUN	_	Number=Sing	_	_	_	_
8	impacted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	activating	_	NOUN	_	VerbForm=Ger	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	element	_	NOUN	_	Number=Sing	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	ATF	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	CREB	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	site	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	between	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	LEF	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	distal	_	ADJ	_	Degree=Pos	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
41	transcription	_	NOUN	_	Number=Sing	_	_	_	_
42	factor	_	NOUN	_	Number=Sing	_	_	_	_
43	binding	_	NOUN	_	VerbForm=Ger	_	_	_	_
44	sites	_	NOUN	_	Number=Plur	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	that	_	PRON	_	PronType=Rel	_	_	_	_
47	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
48	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	previous	_	ADJ	_	Degree=Pos	_	_	_	_
51	studies	_	NOUN	_	Number=Plur	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	HIV	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	1	_	NUM	_	NumType=Card	_	_	_	_
57	LTR	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	LTR	_	PROPN	_	Number=Sing	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	changes	_	NOUN	_	Number=Plur	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	significantly	_	ADV	_	_	_	_	_	_
10	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
11	basal	_	ADJ	_	Degree=Pos	_	_	_	_
12	LTR	_	NOUN	_	Number=Sing	_	_	_	_
13	function	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	turn	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	alter	_	ADP	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	course	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	viral	_	ADJ	_	Degree=Pos	_	_	_	_
30	replication	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	CNS	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	immune	_	ADJ	_	Degree=Pos	_	_	_	_
37	system	_	NOUN	_	Number=Sing	_	_	_	_
38	origin	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011683	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	GATA	_	NOUN	_	Number=Sing	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	associate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	novel	_	NOUN	_	Number=Sing	_	_	_	_
8	class	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	bodies	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	megakaryocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	distribution	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	GATA	_	NOUN	_	Number=Sing	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	murine	_	NOUN	_	Number=Sing	_	_	_	_
10	haemopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	indirect	_	ADJ	_	Degree=Pos	_	_	_	_
16	immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Specific	_	ADJ	_	Degree=Pos	_	_	_	_
2	bright	_	ADJ	_	Degree=Pos	_	_	_	_
3	foci	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	GATA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	fluorescence	_	NOUN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	erythroleukaemia	_	ADJ	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	primary	_	ADJ	_	Degree=Pos	_	_	_	_
16	murine	_	NOUN	_	Number=Sing	_	_	_	_
17	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	megakaryocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	addition	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	diffuse	_	VERB	_	VerbForm=Inf	_	_	_	_
25	nucleoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
26	localization	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	foci	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	preferentially	_	ADV	_	_	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	nucleoli	_	NOUN	_	Number=Plur	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	periphery	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
20	sites	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	active	_	ADJ	_	Degree=Pos	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	GATA	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	consensus	_	NOUN	_	Number=Sing	_	_	_	_
32	sites	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	beta	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	globin	_	NOUN	_	Number=Sing	_	_	_	_
38	loci	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Immunoelectron	_	PROPN	_	Degree=Pos	_	_	_	_
2	microscopy	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	presence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	intensely	_	ADV	_	_	_	_	_	_
8	labelled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	structures	_	NOUN	_	Number=Plur	_	_	_	_
10	likely	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	GATA	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	foci	_	NOUN	_	Number=Sing	_	_	_	_
18	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GATA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	bodies	_	NOUN	_	Number=Plur	_	_	_	_
7	differed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	previously	_	ADV	_	_	_	_	_	_
10	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	structures	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	there	_	PRON	_	_	_	_	_	_
15	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	no	_	DET	_	_	_	_	_	_
17	co-localization	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	antigens	_	NOUN	_	Number=Plur	_	_	_	_
21	involved	_	ADJ	_	Degree=Pos	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	RNA	_	PROPN	_	Number=Sing	_	_	_	_
24	processing	_	NOUN	_	Number=Sing	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	other	_	ADJ	_	Degree=Pos	_	_	_	_
27	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	Spl	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	c	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	Jun	_	PROPN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	TBP	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	haemopoietic	_	ADJ	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	E2	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	transcription	_	NOUN	_	Number=Sing	_	_	_	_
45	factors	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	GATA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	GATA	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	localized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	same	_	ADJ	_	Degree=Pos	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	bodies	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	lines	_	NOUN	_	Number=Plur	_	_	_	_
21	co-expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	GATA	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	GATA	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	-	_	SYM	_	_	_	_	_	_
34	3	_	NUM	_	NumType=Card	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	products	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	pattern	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	distribution	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	thus	_	ADV	_	_	_	_	_	_
8	far	_	ADV	_	Degree=Pos	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	unique	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	GATA	_	NOUN	_	Number=Sing	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	interaction	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	other	_	ADJ	_	Degree=Pos	_	_	_	_
25	components	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	bodies	_	NOUN	_	Number=Plur	_	_	_	_
30	via	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	GATA	_	PROPN	_	Number=Sing	_	_	_	_
33	zinc	_	NOUN	_	Number=Sing	_	_	_	_
34	finger	_	NOUN	_	Number=Sing	_	_	_	_
35	domain	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011685	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	sodium	_	NOUN	_	Number=Sing	_	_	_	_
9	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
12	[	_	PUNCT	_	_	_	_	_	_
13	see	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
14	comments	_	NOUN	_	Number=Plur	_	_	_	_
15	]	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	critical	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
23	cellular	_	NOUN	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	viral	_	ADJ	_	Degree=Pos	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	infection	_	NOUN	_	Number=Sing	_	_	_	_
32	including	_	VERB	_	VerbForm=Ger	_	_	_	_
33	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	6	_	NUM	_	NumType=Card	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
48	molecules	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	drugs	_	NOUN	_	Number=Plur	_	_	_	_
4	sodium	_	NOUN	_	Number=Sing	_	_	_	_
5	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	PROPN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	further	_	ADV	_	_	_	_	_	_
19	explains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	action	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	drugs	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	degradation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	kappa	_	VERB	_	Number=Sing	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	therefore	_	ADV	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	retained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Sodium	_	NOUN	_	Number=Sing	_	_	_	_
2	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	Ig	_	PROPN	_	Number=Sing	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
23	virus	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	long	_	ADJ	_	Degree=Pos	_	_	_	_
28	terminal	_	NOUN	_	Number=Sing	_	_	_	_
29	repeat	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	LTR	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	T	_	NOUN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011687	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Costimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
4	blood	_	NOUN	_	Number=Sing	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	correlates	_	VERB	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
10	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	Fos	_	NOUN	_	Number=Sing	_	_	_	_
14	content	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	AP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_
20	Endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	EC	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	act	_	VERB	_	Number=Sing	_	_	_	_
26	as	_	ADP	_	_	_	_	_	_
27	APC	_	NOUN	_	Number=Sing	_	_	_	_
28	for	_	SCONJ	_	_	_	_	_	_
29	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
30	PBL	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	vitro	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	may	_	AUX	_	VerbForm=Fin	_	_	_	_
36	have	_	VERB	_	VerbForm=Inf	_	_	_	_
37	important	_	ADJ	_	Degree=Pos	_	_	_	_
38	roles	_	NOUN	_	Number=Plur	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	vivo	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	allograft	_	NOUN	_	Number=Sing	_	_	_	_
46	rejection	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
49	hypersensitivity	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
7	vein	_	NOUN	_	Number=Sing	_	_	_	_
8	EC	_	PROPN	_	Number=Sing	_	_	_	_
9	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
10	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	signals	_	NOUN	_	Number=Plur	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	PHA	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	PBL	_	NOUN	_	Number=Sing	_	_	_	_
17	via	_	ADP	_	_	_	_	_	_
18	CD2	_	NOUN	_	Number=Sing	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	function	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	Ag	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	3	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	unidentified	_	ADJ	_	Degree=Pos	_	_	_	_
30	ligand	_	NOUN	_	Number=Sing	_	_	_	_
31	pair	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	three	_	NUM	_	NumType=Card	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	eight	_	NUM	_	NumType=Card	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	fold	_	VERB	_	Number=Sing	_	_	_	_
42	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	IL	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	2	_	NUM	_	NumType=Card	_	_	_	_
47	production	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	physiologic	_	ADJ	_	Degree=Pos	_	_	_	_
3	relevance	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	increase	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
12	advantage	_	NOUN	_	Number=Sing	_	_	_	_
13	provided	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	EC	_	PROPN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	PBL	_	PROPN	_	Number=Sing	_	_	_	_
18	suboptimally	_	ADV	_	_	_	_	_	_
19	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	mAb	_	NOUN	_	Number=Sing	_	_	_	_
22	OKT3	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	EC	_	PROPN	_	Number=Sing	_	_	_	_
6	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	result	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	PBL	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	EC	_	PROPN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	including	_	VERB	_	VerbForm=Ger	_	_	_	_
22	c	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	jun	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	two	_	NUM	_	NumType=Card	_	_	_	_
29	components	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	AP	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	others	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	PBL	_	PROPN	_	Number=Sing	_	_	_	_
2	constitutively	_	ADV	_	_	_	_	_	_
3	express	_	VERB	_	Degree=Pos	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	jun	_	NOUN	_	Number=Sing	_	_	_	_
7	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	level	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	c	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	jun	_	NOUN	_	Number=Sing	_	_	_	_
16	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	PHA	_	PROPN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	absence	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	presence	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	EC	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	fos	_	ADP	_	Number=Sing	_	_	_	_
7	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	absent	_	VERB	_	Degree=Pos	_	_	_	_
10	from	_	SCONJ	_	_	_	_	_	_
11	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	PHA	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	EC	_	PROPN	_	Number=Sing	_	_	_	_
2	alone	_	ADV	_	_	_	_	_	_
3	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
6	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
7	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	augment	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	level	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	c	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	fos	_	ADP	_	Number=Sing	_	_	_	_
16	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	PHA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	10	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	fold	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	largely	_	ADV	_	_	_	_	_	_
5	independent	_	ADJ	_	Degree=Pos	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	CD2	_	NOUN	_	Number=Sing	_	_	_	_
9	:	_	PUNCT	_	_	_	_	_	_
10	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	function	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	Ag	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	3	_	NUM	_	NumType=Card	_	_	_	_
17	pathway	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	reveals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
8	presence	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	SCONJ	_	_	_	_	_	_
13	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
14	PBL	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
32	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	immunoreactive	_	ADJ	_	Degree=Pos	_	_	_	_
34	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
35	but	_	CCONJ	_	_	_	_	_	_
36	not	_	PART	_	_	_	_	_	_
37	c	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	Fos	_	PROPN	_	Number=Sing	_	_	_	_
40	protein	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	PHA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	c	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	Jun	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	low	_	ADJ	_	Degree=Pos	_	_	_	_
18	levels	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Strikingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	EC	_	NOUN	_	Number=Sing	_	_	_	_
6	results	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
10	increase	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	up	_	ADP	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	15	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	fold	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	c	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	Fos	_	NOUN	_	Number=Sing	_	_	_	_
23	content	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	AP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_
29	Levels	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	other	_	ADJ	_	Degree=Pos	_	_	_	_
32	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
33	factors	_	NOUN	_	Number=Plur	_	_	_	_
34	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	regulation	_	NOUN	_	Number=Sing	_	_	_	_
40	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	not	_	PART	_	_	_	_	_	_
42	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	EC	_	PROPN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	although	_	SCONJ	_	_	_	_	_	_
47	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	DNA	_	PROPN	_	Number=Sing	_	_	_	_
50	complexes	_	NOUN	_	Number=Plur	_	_	_	_
51	migrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
52	at	_	ADP	_	_	_	_	_	_
53	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
54	slightly	_	ADV	_	_	_	_	_	_
55	different	_	ADJ	_	Degree=Pos	_	_	_	_
56	mobility	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	summary	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	changes	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	composition	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	AP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	key	_	ADJ	_	Degree=Pos	_	_	_	_
21	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
22	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	SCONJ	_	_	_	_	_	_
24	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	may	_	AUX	_	VerbForm=Fin	_	_	_	_
31	underlie	_	VERB	_	VerbForm=Inf	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	EC	_	PROPN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011690	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	c	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Rel	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	target	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	pentoxifylline	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
11	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	possible	_	ADJ	_	Degree=Pos	_	_	_	_
3	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
4	use	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	methyl	_	ADJ	_	Number=Sing	_	_	_	_
8	xanthine	_	NOUN	_	Number=Sing	_	_	_	_
9	derivative	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	pentoxifylline	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	PF	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	treatment	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	T	_	NUM	_	NumType=Card	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
24	diseases	_	NOUN	_	Number=Plur	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	being	_	AUX	_	VerbForm=Ger	_	_	_	_
27	noted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
30	interest	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	paper	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
9	consequences	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	PF	_	NOUN	_	Number=Sing	_	_	_	_
12	treatment	_	NOUN	_	Number=Sing	_	_	_	_
13	during	_	ADP	_	_	_	_	_	_
14	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Number=Sing	_	_	_	_

1	c	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Rel	_	NOUN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	PF	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	whereas	_	SCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	other	_	ADJ	_	Degree=Pos	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	family	_	NOUN	_	Number=Sing	_	_	_	_
19	members	_	NOUN	_	Number=Plur	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	significantly	_	ADV	_	_	_	_	_	_
23	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	AT	_	ADP	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	same	_	ADJ	_	Degree=Pos	_	_	_	_
13	signaling	_	NOUN	_	Number=Sing	_	_	_	_
14	requirements	_	NOUN	_	Number=Plur	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	c	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	Rel	_	NOUN	_	Number=Sing	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	PF	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Among	_	ADP	_	_	_	_	_	_
2	genes	_	NOUN	_	Number=Plur	_	_	_	_
3	that	_	PRON	_	PronType=Rel	_	_	_	_
4	respond	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	PF	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	whereas	_	SCONJ	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2R	_	PROPN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	chain	_	NOUN	_	Number=Sing	_	_	_	_
28	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
29	induction	_	NOUN	_	Number=Sing	_	_	_	_
30	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
31	not	_	PART	_	_	_	_	_	_
32	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	implicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	Rel	_	NOUN	_	Number=Sing	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Int	_	_	_	_
17	experimental	_	ADJ	_	Degree=Pos	_	_	_	_
18	support	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	transient	_	ADJ	_	Degree=Pos	_	_	_	_
23	transfection	_	NOUN	_	Number=Sing	_	_	_	_
24	experiments	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	observation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	c	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Rel	_	NOUN	_	Number=Sing	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	PF	_	PROPN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	B	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
3	selectivity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	PF	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	FK506	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
17	levels	_	NOUN	_	Number=Plur	_	_	_	_
18	may	_	AUX	_	VerbForm=Fin	_	_	_	_
19	prove	_	VERB	_	VerbForm=Inf	_	_	_	_
20	advantageous	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	SCONJ	_	_	_	_	_	_
22	manipulating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	responses	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	vivo	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011694	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Calcineurin	_	PROPN	_	Number=Sing	_	_	_	_
2	potentiates	_	VERB	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
9	colony	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	:	_	PUNCT	_	_	_	_	_	_
18	involvement	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	conserved	_	VERB	_	Degree=Pos	_	_	_	_
22	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
23	element	_	NOUN	_	Number=Sing	_	_	_	_
24	0	_	NUM	_	NumType=Card	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
4	colony	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	GM	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	CSF	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	_	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	12	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	myristate	_	NOUN	_	Number=Sing	_	_	_	_
32	acetate	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	PMA	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	calcium	_	NOUN	_	Number=Sing	_	_	_	_
38	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	A23187	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	human	_	ADJ	_	Degree=Pos	_	_	_	_
44	T	_	NOUN	_	Number=Sing	_	_	_	_
45	cell	_	NOUN	_	Number=Sing	_	_	_	_
46	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
47	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	GM	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	CSF	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
15	drugs	_	NOUN	_	Number=Plur	_	_	_	_
16	such	_	ADJ	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
19	A	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	CsA	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	FK506	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Earlier	_	ADJ	_	Degree=Cmp	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	CN	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	Ca2+/	_	NOUN	_	Number=Sing	_	_	_	_
21	calmodulin-dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	can	_	AUX	_	VerbForm=Fin	_	_	_	_
26	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	through	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	AT	_	ADP	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	binding	_	NOUN	_	Number=Sing	_	_	_	_
41	site	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	obtained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	evidence	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	DET	_	_	_	_	_	_
9	transfection	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	cDNAs	_	NOUN	_	Number=Plur	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	CN	_	PROPN	_	Number=Sing	_	_	_	_
15	A	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	catalytic	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	CN	_	PROPN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	subunits	_	NOUN	_	Number=Plur	_	_	_	_
26	also	_	ADV	_	_	_	_	_	_
27	augments	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	GM	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	CSF	_	NOUN	_	Number=Sing	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	recovers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	CsA	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	constitutively	_	ADV	_	_	_	_	_	_
3	active	_	ADJ	_	Degree=Pos	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	CN	_	PROPN	_	Number=Sing	_	_	_	_
8	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	subunit	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	lacks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	auto	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	calmodulin	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	domains	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	acts	_	VERB	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	synergy	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	PMA	_	PROPN	_	Number=Sing	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	GM	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	CSF	_	NOUN	_	Number=Sing	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	active	_	ADJ	_	Degree=Pos	_	_	_	_
7	CN	_	PROPN	_	Number=Sing	_	_	_	_
8	partially	_	ADV	_	_	_	_	_	_
9	replaces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	calcium	_	NOUN	_	Number=Sing	_	_	_	_
11	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	synergy	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	PMA	_	PROPN	_	Number=Sing	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
21	GM	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	CSF	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	multimerizing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	GM	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CSF	_	PROPN	_	Number=Sing	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	one	_	NUM	_	NumType=Card	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	target	_	NOUN	_	Number=Sing	_	_	_	_
20	sites	_	NOUN	_	Number=Plur	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	CN	_	PROPN	_	Number=Sing	_	_	_	_
24	action	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	conserved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
28	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
29	element	_	NOUN	_	Number=Sing	_	_	_	_
30	0	_	NUM	_	NumType=Card	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	CLE0	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	at	_	ADP	_	_	_	_	_	_
37	positions	_	NOUN	_	Number=Plur	_	_	_	_
38	between	_	ADP	_	_	_	_	_	_
39	-	_	SYM	_	_	_	_	_	_
40	54	_	NUM	_	NumType=Card	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	-	_	SYM	_	_	_	_	_	_
43	40	_	NUM	_	NumType=Card	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Mobility	_	NOUN	_	Number=Sing	_	_	_	_
2	shift	_	NOUN	_	Number=Sing	_	_	_	_
3	assays	_	NOUN	_	Number=Plur	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	CLE0	_	PROPN	_	Number=Sing	_	_	_	_
8	sequence	_	NOUN	_	Number=Sing	_	_	_	_
9	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	AP1	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	AT	_	ADP	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	like	_	ADJ	_	Degree=Pos	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	CLE0	_	PROPN	_	Number=Sing	_	_	_	_
31	gamma	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	CLE0	_	PROPN	_	Number=Sing	_	_	_	_
4	gamma	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	PMA	_	PROPN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	A23187	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	treatment	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	CsA	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CN	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	involved	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	coordinated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	GM	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	CSF	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	CLE0	_	NOUN	_	Number=Sing	_	_	_	_
26	sequence	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	GM	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	CSF	_	PROPN	_	Number=Sing	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	functional	_	ADJ	_	Degree=Pos	_	_	_	_
36	analogue	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	AT	_	ADP	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	binding	_	NOUN	_	Number=Sing	_	_	_	_
44	site	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	IL	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	2	_	NUM	_	NumType=Card	_	_	_	_
50	promoter	_	NOUN	_	Number=Sing	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	which	_	PRON	_	PronType=Rel	_	_	_	_
53	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
54	signals	_	VERB	_	Number=Plur	_	_	_	_
55	downstream	_	ADV	_	Degree=Pos	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	T	_	NOUN	_	Number=Sing	_	_	_	_
58	cell	_	NOUN	_	Number=Sing	_	_	_	_
59	activation	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011702	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Distinct	_	ADJ	_	Degree=Pos	_	_	_	_
2	signaling	_	VERB	_	Number=Sing	_	_	_	_
3	properties	_	NOUN	_	Number=Plur	_	_	_	_
4	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	functionally	_	ADV	_	_	_	_	_	_
6	different	_	ADJ	_	Degree=Pos	_	_	_	_
7	CD4	_	PROPN	_	Number=Sing	_	_	_	_
8	epitopes	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CD4	_	PROPN	_	Number=Sing	_	_	_	_
3	coreceptor	_	NOUN	_	Number=Sing	_	_	_	_
4	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	non-polymorphic	_	ADJ	_	Degree=Pos	_	_	_	_
7	regions	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	major	_	ADJ	_	Degree=Pos	_	_	_	_
10	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
11	complex	_	NOUN	_	Number=Sing	_	_	_	_
12	class	_	NOUN	_	Number=Sing	_	_	_	_
13	II	_	NUM	_	NumType=Card	_	_	_	_
14	molecules	_	NOUN	_	Number=Plur	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	antigen	_	ADJ	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	presenting	_	VERB	_	VerbForm=Ger	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	contributes	_	VERB	_	Number=Plur	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CD4	_	PROPN	_	Number=Sing	_	_	_	_
8	triggering	_	VERB	_	VerbForm=Ger	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	activating	_	NOUN	_	VerbForm=Ger	_	_	_	_
13	signals	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
17	model	_	NOUN	_	Number=Sing	_	_	_	_
18	using	_	VERB	_	VerbForm=Ger	_	_	_	_
19	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
20	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	mAb	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	recognize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	different	_	ADJ	_	Degree=Pos	_	_	_	_
27	CD4	_	NOUN	_	Number=Sing	_	_	_	_
28	epitopes	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	CD4	_	PROPN	_	Number=Sing	_	_	_	_
5	triggering	_	NOUN	_	Number=Sing	_	_	_	_
6	delivers	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	signals	_	NOUN	_	Number=Plur	_	_	_	_
8	capable	_	ADJ	_	Degree=Pos	_	_	_	_
9	of	_	SCONJ	_	_	_	_	_	_
10	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	AT	_	ADP	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	different	_	ADJ	_	Degree=Pos	_	_	_	_
3	anti-CD4	_	PROPN	_	Number=Sing	_	_	_	_
4	mAb	_	NOUN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	HIV	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	gp120	_	NOUN	_	Number=Sing	_	_	_	_
10	could	_	AUX	_	VerbForm=Fin	_	_	_	_
11	all	_	ADV	_	_	_	_	_	_
12	trigger	_	VERB	_	VerbForm=Inf	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
18	kinases	_	NOUN	_	Number=Plur	_	_	_	_
19	p56lck	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	p59fyn	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	Shc	_	PROPN	_	Number=Sing	_	_	_	_
27	adaptor	_	NOUN	_	Number=Sing	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	which	_	PRON	_	PronType=Rel	_	_	_	_
31	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	signals	_	NOUN	_	Number=Plur	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	Ras	_	PROPN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
37	differed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	significantly	_	ADV	_	_	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
41	ability	_	NOUN	_	Number=Sing	_	_	_	_
42	to	_	PART	_	_	_	_	_	_
43	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
44	NF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	AT	_	ADP	_	_	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Lack	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	full	_	ADJ	_	Degree=Pos	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	AT	_	NOUN	_	Number=Sing	_	_	_	_
9	could	_	AUX	_	VerbForm=Fin	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	dramatically	_	ADV	_	_	_	_	_	_
15	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	capacity	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
19	calcium	_	NOUN	_	Number=Sing	_	_	_	_
20	flux	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	could	_	AUX	_	VerbForm=Fin	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	complemented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	calcium	_	NOUN	_	Number=Sing	_	_	_	_
28	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	functionally	_	ADV	_	_	_	_	_	_
5	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
6	epitopes	_	NOUN	_	Number=Plur	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	CD4	_	PROPN	_	Number=Sing	_	_	_	_
10	coreceptor	_	NOUN	_	Number=Sing	_	_	_	_
11	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	Ras	_	PROPN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	kinase	_	NOUN	_	Number=Sing	_	_	_	_
20	C	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	calcium	_	NOUN	_	Number=Sing	_	_	_	_
23	pathways	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011707	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	replication	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	Tat	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	activated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	interferon	_	NOUN	_	Degree=Pos	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	:	_	PUNCT	_	_	_	_	_	_
19	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
24	virus	_	NOUN	_	Number=Sing	_	_	_	_
25	type	_	NOUN	_	Number=Sing	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	feasibility	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	SCONJ	_	_	_	_	_	_
7	using	_	VERB	_	VerbForm=Ger	_	_	_	_
8	interferon	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	IFN	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	transfer	_	NOUN	_	Number=Sing	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	novel	_	NOUN	_	Number=Sing	_	_	_	_
17	approach	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	anti-human	_	ADJ	_	Degree=Pos	_	_	_	_
20	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
21	virus	_	NOUN	_	Number=Sing	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	therapy	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
32	study	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	limit	_	VERB	_	VerbForm=Inf	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	long	_	ADJ	_	Degree=Pos	_	_	_	_
11	terminal	_	NOUN	_	Number=Sing	_	_	_	_
12	repeat	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	LTR	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	IFNA2	_	PROPN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	new	_	ADJ	_	Degree=Pos	_	_	_	_
21	approved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	nomenclature	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	IFN	_	PROPN	_	Number=Sing	_	_	_	_
25	genes	_	NOUN	_	Number=Plur	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	throughout	_	ADP	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	article	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	HIV	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	HIV	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	LTR	_	NOUN	_	Number=Sing	_	_	_	_
47	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
48	modified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	elements	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	HIV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	LTR	_	PROPN	_	Number=Sing	_	_	_	_
15	significantly	_	ADV	_	_	_	_	_	_
16	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	Tat	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	mediated	_	VERB	_	Degree=Pos	_	_	_	_
20	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
23	lines	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	as	_	ADV	_	_	_	_	_	_
26	well	_	ADV	_	Degree=Pos	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
31	line	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	U937	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Replacement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	elements	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	HIV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	LTR	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	DNA	_	PROPN	_	Number=Sing	_	_	_	_
18	fragment	_	NOUN	_	Number=Sing	_	_	_	_
19	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	5'-	_	NOUN	_	_	_	_	_	_
23	flanking	_	VERB	_	Number=Sing	_	_	_	_
24	region	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	IFN	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	15	_	NUM	_	NumType=Card	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	ISG15	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	IFN	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	response	_	NOUN	_	Number=Sing	_	_	_	_
41	element	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	partially	_	ADV	_	_	_	_	_	_
44	restored	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	Tat	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
48	activation	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	LTR	_	NOUN	_	Number=Sing	_	_	_	_
51	in	_	ADP	_	_	_	_	_	_
52	T	_	PROPN	_	Number=Sing	_	_	_	_
53	cells	_	NOUN	_	Number=Plur	_	_	_	_
54	as	_	ADV	_	_	_	_	_	_
55	well	_	ADV	_	Degree=Pos	_	_	_	_
56	as	_	ADP	_	_	_	_	_	_
57	in	_	ADP	_	_	_	_	_	_
58	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Insertion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	chimeric	_	ADJ	_	Degree=Pos	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	ISG15	_	PROPN	_	Number=Sing	_	_	_	_
8	LTR	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	upstream	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	IFNA2	_	PROPN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	high	_	ADJ	_	Degree=Pos	_	_	_	_
18	levels	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	IFN	_	PROPN	_	Number=Sing	_	_	_	_
21	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	Tat	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	while	_	SCONJ	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
32	not	_	PART	_	_	_	_	_	_
33	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	tumor	_	NOUN	_	VerbForm=Inf	_	_	_	_
36	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
37	factor	_	NOUN	_	Number=Sing	_	_	_	_
38	alpha	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	activation	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	ISG15-LTR-IFN	_	PROPN	_	Degree=Pos	_	_	_	_
2	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	inserted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	into	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	retrovirus	_	NOUN	_	Number=Sing	_	_	_	_
8	vector	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	transduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	into	_	ADP	_	_	_	_	_	_
12	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	U937	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	transfected	_	VERB	_	Degree=Pos	_	_	_	_
3	clones	_	NOUN	_	Number=Plur	_	_	_	_
4	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	low	_	ADJ	_	Degree=Pos	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IFN	_	PROPN	_	Number=Sing	_	_	_	_
9	A	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	IFNA	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	constitutively	_	ADV	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	abilities	_	NOUN	_	Number=Plur	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	express	_	VERB	_	VerbForm=Inf	_	_	_	_
20	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	upon	_	ADP	_	_	_	_	_	_
29	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
34	myristate	_	NOUN	_	Number=Sing	_	_	_	_
35	acetate	_	NOUN	_	Number=Sing	_	_	_	_
36	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	retained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Enhancement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IFNA	_	PROPN	_	Number=Sing	_	_	_	_
4	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
5	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	upon	_	ADP	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	infection	_	NOUN	_	Number=Sing	_	_	_	_
11	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	significant	_	ADJ	_	Degree=Pos	_	_	_	_
14	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	replication	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	period	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	at	_	ADV	_	_	_	_	_	_
25	least	_	ADV	_	Degree=Sup	_	_	_	_
26	30	_	NUM	_	NumType=Card	_	_	_	_
27	days	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Virus	_	NOUN	_	Number=Sing	_	_	_	_
2	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	IFNA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	able	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	U937	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	efficiently	_	ADV	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	U937	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	IFNA	_	PROPN	_	Degree=Pos	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	targeting	_	VERB	_	VerbForm=Ger	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	HIV	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	attainable	_	ADJ	_	Degree=Pos	_	_	_	_
18	goal	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	that	_	DET	_	_	_	_	_	_
21	autocrine	_	NOUN	_	Number=Sing	_	_	_	_
22	IFN	_	PROPN	_	Number=Sing	_	_	_	_
23	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
24	results	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	long	_	ADJ	_	Degree=Pos	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	lasting	_	ADJ	_	Degree=Pos	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	permanent	_	ADJ	_	Degree=Pos	_	_	_	_
32	suppression	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	HIV	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	replication	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011711	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	thyrotropin	_	NOUN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	autoimmune	_	VERB	_	Degree=Pos	_	_	_	_
10	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
11	disease	_	NOUN	_	Number=Sing	_	_	_	_
12	:	_	PUNCT	_	_	_	_	_	_
13	coregulation	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	parameters	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
18	function	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	inverse	_	ADJ	_	Degree=Pos	_	_	_	_
21	relation	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	major	_	ADJ	_	Degree=Pos	_	_	_	_
24	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
25	complex	_	NOUN	_	Number=Sing	_	_	_	_
26	classes	_	NOUN	_	Number=Plur	_	_	_	_
27	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	II	_	NUM	_	NumType=Card	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	TSH	_	NOUN	_	Number=Sing	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	TSH	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	R	_	X	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
12	probe	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	TSH	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	R	_	NOUN	_	Number=Sing	_	_	_	_
19	transcript	_	NOUN	_	Number=Sing	_	_	_	_
20	levels	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	13	_	NUM	_	NumType=Card	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
25	fragments	_	NOUN	_	Number=Plur	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
28	blot	_	NOUN	_	Number=Sing	_	_	_	_
29	analysis	_	NOUN	_	Number=Sing	_	_	_	_
30	;	_	PUNCT	_	_	_	_	_	_
31	7	_	NUM	_	NumType=Card	_	_	_	_
32	Graves	_	PROPN	_	Number=Plur	_	_	_	_
33	'	_	PART	_	_	_	_	_	_
34	disease	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	Hashimoto	_	PROPN	_	Number=Sing	_	_	_	_
38	's	_	PART	_	_	_	_	_	_
39	disease	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	3	_	NUM	_	NumType=Card	_	_	_	_
42	endemic	_	ADJ	_	Degree=Pos	_	_	_	_
43	goiter	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
48	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
49	gland	_	NOUN	_	Number=Sing	_	_	_	_
50	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
51	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	TSH	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	R	_	NOUN	_	_	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	variable	_	ADJ	_	Degree=Pos	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	displayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	close	_	ADJ	_	Degree=Pos	_	_	_	_
13	correlation	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
19	peroxidase	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	r	_	NOUN	_	Number=Sing	_	_	_	_
22	=	_	SYM	_	_	_	_	_	_
23	0.703	_	NUM	_	NumType=Card	_	_	_	_
24	;	_	PUNCT	_	_	_	_	_	_
25	P	_	NOUN	_	Number=Sing	_	_	_	_
26	<	_	PUNCT	_	_	_	_	_	_
27	0.05	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	thyroglobulin	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	r	_	NOUN	_	Number=Sing	_	_	_	_
33	=	_	SYM	_	_	_	_	_	_
34	0.817	_	NUM	_	NumType=Card	_	_	_	_
35	;	_	PUNCT	_	_	_	_	_	_
36	P	_	NOUN	_	Number=Sing	_	_	_	_
37	<	_	PUNCT	_	_	_	_	_	_
38	0.01	_	NUM	_	NumType=Card	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
44	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
45	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	r	_	NOUN	_	Number=Sing	_	_	_	_
48	=	_	SYM	_	_	_	_	_	_
49	0.935	_	NUM	_	NumType=Card	_	_	_	_
50	;	_	PUNCT	_	_	_	_	_	_
51	P	_	NOUN	_	Number=Sing	_	_	_	_
52	<	_	PUNCT	_	_	_	_	_	_
53	0.001	_	NUM	_	NumType=Card	_	_	_	_
54	)	_	PUNCT	_	_	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	but	_	CCONJ	_	_	_	_	_	_
57	not	_	PART	_	_	_	_	_	_
58	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Overall	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	TSH	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	R	_	NOUN	_	Number=Sing	_	_	_	_
6	transcript	_	NOUN	_	Number=Sing	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	low	_	ADJ	_	Degree=Pos	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	absent	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	thyroids	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	which	_	DET	_	PronType=Rel	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	major	_	ADJ	_	Degree=Pos	_	_	_	_
21	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
22	complex	_	NOUN	_	Number=Sing	_	_	_	_
23	class	_	NOUN	_	Number=Sing	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	II	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	MHC	_	PROPN	_	Number=Sing	_	_	_	_
29	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	II	_	NUM	_	NumType=Card	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
34	high	_	ADJ	_	Degree=Pos	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	thus	_	ADV	_	_	_	_	_	_
37	establishing	_	VERB	_	VerbForm=Ger	_	_	_	_
38	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	inverse	_	ADJ	_	Degree=Pos	_	_	_	_
40	relation	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	MHC	_	PROPN	_	Number=Sing	_	_	_	_
43	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	r	_	NOUN	_	Number=Sing	_	_	_	_
46	=	_	SYM	_	_	_	_	_	_
47	-	_	SYM	_	_	_	_	_	_
48	0.791	_	NUM	_	NumType=Card	_	_	_	_
49	;	_	PUNCT	_	_	_	_	_	_
50	P	_	NOUN	_	Number=Sing	_	_	_	_
51	<	_	PUNCT	_	_	_	_	_	_
52	0.01	_	NUM	_	NumType=Card	_	_	_	_
53	;	_	PUNCT	_	_	_	_	_	_
54	MHC	_	PROPN	_	Number=Sing	_	_	_	_
55	II	_	NUM	_	NumType=Card	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	r	_	NOUN	_	Number=Sing	_	_	_	_
58	=	_	SYM	_	_	_	_	_	_
59	-	_	SYM	_	_	_	_	_	_
60	0.784	_	NUM	_	NumType=Card	_	_	_	_
61	;	_	PUNCT	_	_	_	_	_	_
62	P	_	NOUN	_	Number=Sing	_	_	_	_
63	<	_	PUNCT	_	_	_	_	_	_
64	0.01	_	NUM	_	NumType=Card	_	_	_	_
65	)	_	PUNCT	_	_	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	situ	_	NOUN	_	Number=Sing	_	_	_	_
3	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	apart	_	ADV	_	_	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	themselves	_	PRON	_	Number=Plur|Person=3|PronType=Prs	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	source	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	MHC	_	PROPN	_	Number=Sing	_	_	_	_
18	II	_	NUM	_	NumType=Card	_	_	_	_
19	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	gamma	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Interferon	_	PROPN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	only	_	ADV	_	_	_	_	_	_
7	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	Hashimoto	_	PROPN	_	Number=Sing	_	_	_	_
11	's	_	PART	_	_	_	_	_	_
12	goiter	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	next	_	ADV	_	_	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	lymphocyte	_	VERB	_	Number=Sing	_	_	_	_
8	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	active	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	events	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	thyrocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	inverse	_	ADJ	_	Degree=Pos	_	_	_	_
21	relation	_	NOUN	_	Number=Sing	_	_	_	_
22	between	_	ADP	_	_	_	_	_	_
23	functional	_	ADJ	_	Degree=Pos	_	_	_	_
24	parameters	_	NOUN	_	Number=Plur	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	TSH	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	R	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
31	peroxidase	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	thyroglobulin	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	immunological	_	ADJ	_	Degree=Pos	_	_	_	_
40	markers	_	NOUN	_	Number=Plur	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	MHC	_	PROPN	_	Number=Sing	_	_	_	_
43	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	II	_	NUM	_	NumType=Card	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011714	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	vitro	_	ADJ	_	Number=Sing	_	_	_	_
4	globin	_	PROPN	_	Degree=Pos	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	switching	_	VERB	_	Number=Sing	_	_	_	_
7	model	_	NOUN	_	Number=Sing	_	_	_	_
8	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	differentiated	_	VERB	_	Degree=Pos	_	_	_	_
11	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
12	stem	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	mouse	_	NOUN	_	Number=Sing	_	_	_	_
4	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
5	stem	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	ES	_	X	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	study	_	VERB	_	VerbForm=Inf	_	_	_	_
12	globin	_	ADJ	_	Degree=Pos	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	switching	_	VERB	_	VerbForm=Ger	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	vitro	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	ES	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	embryoid	_	ADJ	_	Degree=Pos	_	_	_	_
8	bodies	_	NOUN	_	Number=Plur	_	_	_	_
9	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	full	_	ADJ	_	Degree=Pos	_	_	_	_
12	complement	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	mouse	_	NOUN	_	Number=Sing	_	_	_	_
15	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
16	globin	_	ADJ	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	correct	_	ADJ	_	Degree=Pos	_	_	_	_
21	temporal	_	ADJ	_	Degree=Pos	_	_	_	_
22	order	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	further	_	ADJ	_	Degree=Pos	_	_	_	_
27	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	switch	_	NOUN	_	Number=Sing	_	_	_	_
31	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	fetal	_	NOUN	_	Number=Sing	_	_	_	_
35	/	_	PUNCT	_	_	_	_	_	_
36	adult	_	NOUN	_	Number=Sing	_	_	_	_
37	genes	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	E1	_	PROPN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	coordinately	_	ADV	_	_	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	globin	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	embryoid	_	ADJ	_	Degree=Pos	_	_	_	_
25	bodies	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	experiments	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	ES	_	PROPN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	system	_	NOUN	_	Number=Sing	_	_	_	_
11	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	good	_	ADJ	_	Degree=Pos	_	_	_	_
14	model	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	study	_	VERB	_	VerbForm=Inf	_	_	_	_
17	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
18	development	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	beta-globin	_	ADJ	_	Degree=Pos	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
13	control	_	NOUN	_	Number=Sing	_	_	_	_
14	region	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	DCR	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	introduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	into	_	ADP	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	system	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	globin	_	ADJ	_	Degree=Pos	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	contrast	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	beta	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	globin	_	NOUN	_	Degree=Pos	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	not	_	PART	_	_	_	_	_	_
42	deregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	presence	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	DCR	_	PROPN	_	Number=Sing	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
51	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	strictly	_	ADV	_	_	_	_	_	_
53	as	_	ADP	_	_	_	_	_	_
54	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
55	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
56	gene	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	globin	_	NOUN	_	Degree=Pos	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	competition	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	other	_	ADJ	_	Degree=Pos	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	beta-globin	_	NOUN	_	Number=Sing	_	_	_	_
23	locus	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011715	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	LAZ3	_	NOUN	_	Number=Sing	_	_	_	_
4	/	_	PUNCT	_	_	_	_	_	_
5	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
8	center	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	FC	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	B	_	ADJ	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
16	lymph	_	NOUN	_	Number=Sing	_	_	_	_
17	nodes	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	FC	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	non-Hodgkin	_	ADJ	_	Degree=Pos	_	_	_	_
23	lymphomas	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
2	translocation	_	NOUN	_	Number=Sing	_	_	_	_
3	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	LAZ3	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
18	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	tumorigenesis	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	non-Hodgkin	_	ADJ	_	Degree=Pos	_	_	_	_
24	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	NHL	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	pattern	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	LAZ3	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	BCL6	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	situ	_	NOUN	_	Number=Sing	_	_	_	_
14	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
17	oligonucleotide	_	ADJ	_	Number=Sing	_	_	_	_
18	probes	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	frozen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	tissue	_	NOUN	_	Number=Sing	_	_	_	_
22	sections	_	NOUN	_	Number=Plur	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	five	_	NUM	_	NumType=Card	_	_	_	_
25	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
26	lymph	_	NOUN	_	Number=Sing	_	_	_	_
27	nodes	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	38	_	NUM	_	NumType=Card	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	non	_	X	_	_	_	_	_	_
34	-B	_	NOUN	_	Number=Sing	_	_	_	_
35	NHL	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	LAZ3	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	BCL6	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
14	blot	_	NOUN	_	Number=Sing	_	_	_	_
15	analysis	_	NOUN	_	Number=Sing	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	tissues	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	LAZ3	_	NOUN	_	Number=Sing	_	_	_	_
3	/	_	PUNCT	_	_	_	_	_	_
4	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
5	transcript	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	variety	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	tissues	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	including	_	VERB	_	VerbForm=Ger	_	_	_	_
15	skeletal	_	ADJ	_	Degree=Pos	_	_	_	_
16	muscle	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
19	blood	_	NOUN	_	Number=Sing	_	_	_	_
20	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	weakly	_	ADV	_	Degree=Pos	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	normal	_	ADJ	_	Degree=Pos	_	_	_	_
26	lymph	_	NOUN	_	Number=Sing	_	_	_	_
27	nodes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	tumor	_	NOUN	_	Number=Sing	_	_	_	_
4	samples	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	LAZ3	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	68	_	NUM	_	NumType=Card	_	_	_	_
15	%	_	SYM	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	all	_	DET	_	_	_	_	_	_
18	B	_	NOUN	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	NHL	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	none	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	non-B	_	ADJ	_	Degree=Pos	_	_	_	_
26	lymphomas	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	cases	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	mixed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	small	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	large	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	lymphomas	_	NOUN	_	Number=Plur	_	_	_	_
12	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	LAZ3	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	confined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	neoplastic	_	ADJ	_	Degree=Pos	_	_	_	_
21	follicles	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	follicular	_	ADJ	_	Degree=Pos	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	pattern	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	all	_	DET	_	_	_	_	_	_
10	non-malignant	_	ADJ	_	Degree=Pos	_	_	_	_
11	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
12	lymph	_	NOUN	_	Number=Sing	_	_	_	_
13	nodes	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Hence	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	LAZ3	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
9	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	correlate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	malignancy	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	reflects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	origin	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	B	_	ADJ	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	germinal	_	ADJ	_	Degree=Pos	_	_	_	_
25	centers	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011725	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	PROPN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	C	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	zeta	_	PROPN	_	Number=Sing	_	_	_	_
6	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
15	virus	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
4	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	persistence	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	major	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	reservoir	_	NOUN	_	Number=Sing	_	_	_	_
17	such	_	ADJ	_	Degree=Pos	_	_	_	_
18	as	_	SCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
21	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	HIV	_	PROPN	_	Number=Sing	_	_	_	_
16	long	_	ADJ	_	Degree=Pos	_	_	_	_
17	terminal	_	NOUN	_	Number=Sing	_	_	_	_
18	repeat	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	selectively	_	ADV	_	_	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	following	_	VERB	_	VerbForm=Ger	_	_	_	_
24	HIV	_	NOUN	_	Number=Sing	_	_	_	_
25	infection	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	little	_	ADJ	_	Degree=Pos	_	_	_	_
3	information	_	NOUN	_	Number=Sing	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	to	_	SCONJ	_	_	_	_	_	_
6	what	_	DET	_	PronType=Int	_	_	_	_
7	signal	_	NOUN	_	Number=Sing	_	_	_	_
8	transduction	_	NOUN	_	Number=Sing	_	_	_	_
9	pathways	_	NOUN	_	Number=Plur	_	_	_	_
10	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	available	_	ADJ	_	Degree=Pos	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
24	previous	_	ADJ	_	Degree=Pos	_	_	_	_
25	work	_	NOUN	_	Number=Sing	_	_	_	_
26	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	classical	_	ADJ	_	Degree=Pos	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	C	_	PROPN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	PKC	_	PROPN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	isoenzymes	_	NOUN	_	Number=Plur	_	_	_	_
36	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	not	_	PART	_	_	_	_	_	_
38	involved	_	ADJ	_	Degree=Pos	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	HIV	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
44	NF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	kappa	_	NOUN	_	Number=Sing	_	_	_	_
47	B	_	NOUN	_	Number=Sing	_	_	_	_
48	activation	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	focused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	atypical	_	ADJ	_	Degree=Pos	_	_	_	_
10	PKC	_	NOUN	_	Number=Sing	_	_	_	_
11	isoenzymes	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	PKC	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	zeta	_	NOUN	_	Number=Sing	_	_	_	_
4	belongs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	family	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	important	_	ADJ	_	Degree=Pos	_	_	_	_
15	step	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	other	_	ADJ	_	Degree=Pos	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	systems	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Immunoblotting	_	VERB	_	Degree=Pos	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	U937	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	PKC	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	zeta	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	present	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	can	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	downmodulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	antisense	_	ADJ	_	Number=Sing	_	_	_	_
25	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	AO	_	NOUN	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	HIV	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	selectively	_	ADV	_	_	_	_	_	_
12	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	AO	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	PKC	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	zeta	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	negative	_	ADJ	_	Degree=Pos	_	_	_	_
8	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
9	molecule	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	PKC	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	zeta	_	PROPN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	PKC	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	zeta	_	NOUN	_	Number=Sing	_	_	_	_
18	mut	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	PROPN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	reporter	_	NOUN	_	Number=Sing	_	_	_	_
28	genes	_	NOUN	_	Number=Plur	_	_	_	_
29	selectively	_	ADV	_	_	_	_	_	_
30	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	HIV	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	not	_	ADV	_	_	_	_	_	_
36	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
37	myristate	_	NOUN	_	Number=Sing	_	_	_	_
38	acetate	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	or	_	CCONJ	_	_	_	_	_	_
41	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	activation	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	NF	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	kappa	_	NOUN	_	Number=Sing	_	_	_	_
49	B.	_	PROPN	_	Number=Sing	_	_	_	_
50	That	_	SCONJ	_	_	_	_	_	_
51	PKC	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	zeta	_	NOUN	_	Number=Sing	_	_	_	_
54	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
55	specific	_	ADJ	_	Degree=Pos	_	_	_	_
56	in	_	SCONJ	_	_	_	_	_	_
57	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
58	NF	_	PROPN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	kappa	_	PROPN	_	Number=Sing	_	_	_	_
61	B	_	PROPN	_	Number=Sing	_	_	_	_
62	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
63	concluded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
64	from	_	ADP	_	_	_	_	_	_
65	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
66	inability	_	NOUN	_	Number=Sing	_	_	_	_
67	of	_	ADP	_	_	_	_	_	_
68	PKC	_	PROPN	_	Number=Sing	_	_	_	_
69	-	_	PUNCT	_	_	_	_	_	_
70	zeta	_	NOUN	_	Number=Sing	_	_	_	_
71	(	_	PUNCT	_	_	_	_	_	_
72	mut	_	NOUN	_	Number=Sing	_	_	_	_
73	)	_	PUNCT	_	_	_	_	_	_
74	to	_	PART	_	_	_	_	_	_
75	interfere	_	VERB	_	VerbForm=Inf	_	_	_	_
76	with	_	ADP	_	_	_	_	_	_
77	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
78	basal	_	NOUN	_	Number=Sing	_	_	_	_
79	or	_	CCONJ	_	_	_	_	_	_
80	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
81	myristate	_	NOUN	_	Number=Sing	_	_	_	_
82	acetate	_	NOUN	_	Number=Sing	_	_	_	_
83	-	_	PUNCT	_	_	_	_	_	_
84	inducible	_	ADJ	_	Number=Sing	_	_	_	_
85	CREB	_	NOUN	_	Number=Sing	_	_	_	_
86	-	_	PUNCT	_	_	_	_	_	_
87	or	_	CCONJ	_	_	_	_	_	_
88	AP1	_	NOUN	_	Number=Sing	_	_	_	_
89	-	_	PUNCT	_	_	_	_	_	_
90	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
91	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
92	activity	_	NOUN	_	Number=Sing	_	_	_	_
93	.	_	PUNCT	_	_	_	_	_	_

1	Lastly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	selective	_	ADJ	_	Degree=Pos	_	_	_	_
7	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	p24	_	NOUN	_	Number=Sing	_	_	_	_
10	production	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
17	when	_	ADV	_	PronType=Int	_	_	_	_
18	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	AO	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	PKC	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	zeta	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Altogether	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	atypical	_	ADJ	_	Degree=Pos	_	_	_	_
8	PKC	_	PROPN	_	Number=Sing	_	_	_	_
9	isoenzymes	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	including	_	VERB	_	VerbForm=Ger	_	_	_	_
12	PKC	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	zeta	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	signal	_	NOUN	_	Number=Sing	_	_	_	_
20	transduction	_	NOUN	_	Number=Sing	_	_	_	_
21	pathways	_	NOUN	_	Number=Plur	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	HIV	_	NOUN	_	Number=Sing	_	_	_	_
25	infection	_	NOUN	_	Number=Sing	_	_	_	_
26	results	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	human	_	ADJ	_	Degree=Pos	_	_	_	_
37	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011727	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	kappa	_	VERB	_	Number=Sing	_	_	_	_
5	B	_	PROPN	_	Number=Sing	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	p105	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
13	persistently	_	ADV	_	_	_	_	_	_
14	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	persistence	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	partially	_	ADV	_	_	_	_	_	_
18	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Persistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	HIV	_	NOUN	_	Number=Sing	_	_	_	_
3	infection	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	U937	_	NUM	_	Number=Sing	_	_	_	_
6	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	results	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Whether	_	SCONJ	_	_	_	_	_	_
2	virus	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	favors	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	continuous	_	ADJ	_	Degree=Pos	_	_	_	_
16	viral	_	ADJ	_	Degree=Pos	_	_	_	_
17	replication	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
20	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	delineate	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
7	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	HIV	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
25	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	focused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	regulation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	I	_	PRON	_	Number=Sing	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	molecules	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	First	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	infection	_	NOUN	_	Number=Sing	_	_	_	_
9	results	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	not	_	ADV	_	_	_	_	_	_
19	only	_	ADV	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	also	_	ADV	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	HIV	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	kappa	_	VERB	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	secondary	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	degradation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	parallels	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	kappa	_	VERB	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
10	secondary	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	kappa	_	VERB	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	i.e.	_	X	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	RNA	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Another	_	DET	_	_	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	kappa	_	VERB	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	function	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	p105	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	modified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	p105	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	p50	_	NUM	_	NumType=Card	_	_	_	_
23	steady	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	state	_	NOUN	_	Number=Sing	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	levels	_	NOUN	_	Number=Plur	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	result	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
38	processing	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	p105	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p105	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	PROPN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	motif	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	existence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	triple	_	ADJ	_	Degree=Pos	_	_	_	_
9	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	loop	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
15	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	p105	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	p50	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	MAD3	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	end	_	NOUN	_	Number=Sing	_	_	_	_
28	result	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
31	NF	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	activation	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	viral	_	ADJ	_	Degree=Pos	_	_	_	_
38	persistence	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	infection	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
10	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	useful	_	ADJ	_	Degree=Pos	_	_	_	_
13	model	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	study	_	VERB	_	VerbForm=Inf	_	_	_	_
18	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
19	modifications	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	different	_	ADJ	_	Degree=Pos	_	_	_	_
22	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
23	kappa	_	VERB	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	molecules	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011731	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	5	_	NUM	_	NumType=Card	_	_	_	_
4	'	_	PUNCT	_	_	_	_	_	_
5	end	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Organizational	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	mapping	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	C--	_	PUNCT	_	_	_	_	_	_
9	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
10	elements	_	NOUN	_	Number=Plur	_	_	_	_
11	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	platelets	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Platelet	_	NOUN	_	Number=Sing	_	_	_	_
2	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
3	receptors	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	acutely	_	ADV	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	reversibly	_	ADV	_	_	_	_	_	_
8	upregulated	_	VERB	_	Degree=Pos	_	_	_	_
9	after	_	ADP	_	_	_	_	_	_
10	acute	_	ADJ	_	Degree=Pos	_	_	_	_
11	myocardial	_	ADJ	_	Degree=Pos	_	_	_	_
12	infarction	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	if	_	SCONJ	_	_	_	_	_	_
4	platelet	_	NOUN	_	Number=Sing	_	_	_	_
5	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
6	receptors	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	under	_	ADP	_	_	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	control	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	isolated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	characterized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
18	DNA	_	PROPN	_	Number=Sing	_	_	_	_
19	clones	_	NOUN	_	Number=Plur	_	_	_	_
20	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	5	_	NUM	_	NumType=Card	_	_	_	_
23	'	_	PUNCT	_	_	_	_	_	_
24	flanking	_	VERB	_	Number=Sing	_	_	_	_
25	region	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	exon	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	intron	_	ADJ	_	Number=Sing	_	_	_	_
5	structure	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	'	_	PUNCT	_	_	_	_	_	_
10	portion	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	initially	_	ADV	_	_	_	_	_	_
19	by	_	SCONJ	_	_	_	_	_	_
20	comparing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
23	sequence	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	5	_	NUM	_	NumType=Card	_	_	_	_
27	'	_	PUNCT	_	_	_	_	_	_
28	flanking	_	VERB	_	VerbForm=Ger	_	_	_	_
29	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
30	clone	_	NOUN	_	Number=Sing	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	novel	_	NOUN	_	Number=Sing	_	_	_	_
36	human	_	ADJ	_	Degree=Pos	_	_	_	_
37	uterine	_	NOUN	_	Number=Sing	_	_	_	_
38	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
39	receptor	_	NOUN	_	Number=Sing	_	_	_	_
40	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
41	that	_	PRON	_	PronType=Rel	_	_	_	_
42	extended	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
45	141	_	NUM	_	NumType=Card	_	_	_	_
46	bp	_	NOUN	_	Number=Sing	_	_	_	_
47	further	_	ADV	_	Degree=Pos	_	_	_	_
48	upstream	_	NOUN	_	Number=Sing	_	_	_	_
49	than	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	previously	_	ADV	_	_	_	_	_	_
52	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
53	human	_	ADJ	_	Degree=Pos	_	_	_	_
54	placental	_	NOUN	_	Degree=Pos	_	_	_	_
55	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	major	_	ADJ	_	Degree=Pos	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	initiation	_	NOUN	_	Number=Sing	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	three	_	NUM	_	NumType=Card	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	tissues	_	NOUN	_	Number=Plur	_	_	_	_
12	approximately	_	ADV	_	_	_	_	_	_
13	560	_	NUM	_	NumType=Card	_	_	_	_
14	bp	_	NOUN	_	Number=Sing	_	_	_	_
15	upstream	_	NOUN	_	Number=Sing	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	translation	_	NOUN	_	Number=Sing	_	_	_	_
19	initiation	_	NOUN	_	Number=Sing	_	_	_	_
20	codon	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	380	_	NUM	_	NumType=Card	_	_	_	_
23	bp	_	PROPN	_	Number=Sing	_	_	_	_
24	upstream	_	NOUN	_	Number=Sing	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	any	_	DET	_	_	_	_	_	_
27	previously	_	ADV	_	_	_	_	_	_
28	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	initiation	_	NOUN	_	Number=Sing	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	neither	_	CCONJ	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	TATA	_	PROPN	_	Number=Sing	_	_	_	_
9	nor	_	CCONJ	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	CAAT	_	NOUN	_	Number=Sing	_	_	_	_
12	consensus	_	NOUN	_	Number=Sing	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Promoter	_	NOUN	_	Number=Sing	_	_	_	_
2	function	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	'	_	PUNCT	_	_	_	_	_	_
7	flanking	_	VERB	_	Number=Sing	_	_	_	_
8	region	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	evaluated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	transfection	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
25	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	CAT	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	chimera	_	NOUN	_	Number=Sing	_	_	_	_
30	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
31	into	_	ADP	_	_	_	_	_	_
32	platelet	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	like	_	ADP	_	_	_	_	_	_
35	K562	_	NUM	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Thromboxane	_	PROPN	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	as	_	SCONJ	_	_	_	_	_	_
7	assessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	CAT	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	relatively	_	ADV	_	_	_	_	_	_
14	weak	_	ADJ	_	Degree=Pos	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	significantly	_	ADV	_	_	_	_	_	_
18	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
21	ester	_	NOUN	_	Number=Sing	_	_	_	_
22	treatment	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	5	_	NUM	_	NumType=Card	_	_	_	_
5	'	_	PUNCT	_	_	_	_	_	_
6	deletion	_	NOUN	_	Number=Sing	_	_	_	_
7	constructs	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	K562	_	NUM	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	gel	_	NOUN	_	Number=Sing	_	_	_	_
14	mobility	_	NOUN	_	Number=Sing	_	_	_	_
15	shift	_	NOUN	_	Number=Sing	_	_	_	_
16	localized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	major	_	ADJ	_	Degree=Pos	_	_	_	_
19	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
20	ester	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
23	motifs	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	cluster	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	activator	_	NOUN	_	Number=Sing	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	AP	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
44	consensus	_	NOUN	_	Number=Sing	_	_	_	_
45	sites	_	NOUN	_	Number=Plur	_	_	_	_
46	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	approximately	_	ADV	_	_	_	_	_	_
48	1.8	_	NUM	_	NumType=Card	_	_	_	_
49	kb	_	NUM	_	Number=Sing	_	_	_	_
50	5	_	NUM	_	NumType=Card	_	_	_	_
51	'	_	NOUN	_	Number=Plur	_	_	_	_
52	from	_	ADP	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	transcription	_	NOUN	_	Number=Sing	_	_	_	_
55	initiation	_	NOUN	_	Number=Sing	_	_	_	_
56	site	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	structure	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	organization	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	5	_	NUM	_	NumType=Card	_	_	_	_
15	'	_	PUNCT	_	_	_	_	_	_
16	end	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	can	_	AUX	_	VerbForm=Fin	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	kinase	_	NOUN	_	Number=Sing	_	_	_	_
37	C	_	PROPN	_	Number=Sing	_	_	_	_
38	via	_	ADP	_	_	_	_	_	_
39	induction	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	AP	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	2	_	NUM	_	NumType=Card	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	like	_	ADJ	_	Degree=Pos	_	_	_	_
47	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
48	factor	_	NOUN	_	Number=Sing	_	_	_	_
49	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	upstream	_	VERB	_	Degree=Pos	_	_	_	_
52	promoter	_	NOUN	_	Number=Sing	_	_	_	_
53	elements	_	NOUN	_	Number=Plur	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	strongly	_	ADV	_	_	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	previously	_	ADV	_	_	_	_	_	_
10	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	platelet	_	NOUN	_	Number=Sing	_	_	_	_
14	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
15	receptors	_	NOUN	_	Number=Plur	_	_	_	_
16	after	_	SCONJ	_	_	_	_	_	_
17	acute	_	ADJ	_	Degree=Pos	_	_	_	_
18	myocardial	_	ADJ	_	Degree=Pos	_	_	_	_
19	infarction	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	thromboxane	_	NOUN	_	Number=Sing	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	platelet	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011736	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Toremifene	_	PROPN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	some	_	DET	_	_	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Toremifene	_	PROPN	_	Number=Sing	_	_	_	_
2	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	varied	_	ADJ	_	Degree=Pos	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
14	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	short	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	term	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	vitro	_	NOUN	_	Number=Sing	_	_	_	_
8	exposure	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	therapeutical	_	ADJ	_	Degree=Pos	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
14	changes	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	P	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	steroid	_	NOUN	_	Number=Sing	_	_	_	_
21	receptors	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	p53	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	take	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	place	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	view	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	use	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	antiestrogens	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	cancer	_	NOUN	_	Number=Sing	_	_	_	_
11	therapy	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	prevention	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	there	_	PRON	_	_	_	_	_	_
16	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	obvious	_	ADJ	_	Degree=Pos	_	_	_	_
18	merit	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	long	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	term	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	vivo	_	NOUN	_	Number=Sing	_	_	_	_
25	studies	_	NOUN	_	Number=Plur	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	conducted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011738	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Role	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HIV	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	Nef	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	pathways	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	CD4	_	PROPN	_	Number=Sing	_	_	_	_
13	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HIV	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	Nef	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	pathways	_	NOUN	_	Number=Plur	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	using	_	VERB	_	VerbForm=Ger	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
25	CD4	_	PROPN	_	Number=Sing	_	_	_	_
26	+	_	SYM	_	_	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	line	_	NOUN	_	Number=Sing	_	_	_	_
29	stably	_	ADV	_	_	_	_	_	_
30	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	Nef	_	NOUN	_	Number=Sing	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	vector	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Secretion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	surface	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2R	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	DNA	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	binding	_	VERB	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	PROPN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	AP	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	Fos	_	PROPN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	Jun	_	PROPN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	complex	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	response	_	NOUN	_	Number=Sing	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
42	myristate	_	NOUN	_	Number=Sing	_	_	_	_
43	acetate	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	TNF	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	alpha	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	or	_	CCONJ	_	_	_	_	_	_
50	immobilized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
52	to	_	ADP	_	_	_	_	_	_
53	CD3	_	PROPN	_	Number=Sing	_	_	_	_
54	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
55	monitored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	parameters	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	modified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	Nef	_	PROPN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	whereas	_	SCONJ	_	_	_	_	_	_
14	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	same	_	ADJ	_	Degree=Pos	_	_	_	_
18	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
19	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	partial	_	ADJ	_	Degree=Pos	_	_	_	_
22	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	LTR	_	NOUN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	Nef	_	PROPN	_	Number=Sing	_	_	_	_
28	+	_	SYM	_	_	_	_	_	_

1	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	through	_	ADP	_	_	_	_	_	_
7	Nef	_	PROPN	_	Number=Sing	_	_	_	_
8	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	Thr	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	15	_	NUM	_	NumType=Card	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	GTP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	because	_	SCONJ	_	_	_	_	_	_
19	mutations	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	critical	_	ADJ	_	Degree=Pos	_	_	_	_
22	sites	_	NOUN	_	Number=Plur	_	_	_	_
23	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
26	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
27	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	truncated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
4	LTRs	_	PROPN	_	Number=Plur	_	_	_	_
5	confirmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	LTR	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	PROPN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	through	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	region	_	NOUN	_	Number=Sing	_	_	_	_
26	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	negative	_	ADJ	_	Degree=Pos	_	_	_	_
29	responding	_	NOUN	_	Number=Sing	_	_	_	_
30	elements	_	NOUN	_	Number=Plur	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	NREs	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Nef	_	PROPN	_	Number=Sing	_	_	_	_
6	downmodulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	LTR	_	PROPN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	without	_	SCONJ	_	_	_	_	_	_
10	significantly	_	ADV	_	_	_	_	_	_
11	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	capacity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	immunological	_	ADJ	_	Degree=Pos	_	_	_	_
21	activations	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011740	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Apoptosis	_	PROPN	_	Number=Sing	_	_	_	_
2	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	protease	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	preceded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	protease	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	cultured	_	VERB	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	preceded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	bcl	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	key	_	ADJ	_	Degree=Pos	_	_	_	_
30	negative	_	ADJ	_	Degree=Pos	_	_	_	_
31	regulator	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	death	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	high	_	ADJ	_	Degree=Pos	_	_	_	_
6	level	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	bcl	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	protects	_	NOUN	_	Number=Plur	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vitro	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	vivo	_	NOUN	_	Number=Sing	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	viral	_	ADJ	_	Degree=Pos	_	_	_	_
21	protease	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	prevents	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	death	_	NOUN	_	Number=Sing	_	_	_	_
26	following	_	VERB	_	VerbForm=Ger	_	_	_	_
27	HIV	_	NOUN	_	Number=Sing	_	_	_	_
28	infection	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	while	_	SCONJ	_	_	_	_	_	_
34	reducing	_	VERB	_	VerbForm=Ger	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	yields	_	NOUN	_	Number=Plur	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	viral	_	ADJ	_	Degree=Pos	_	_	_	_
39	structural	_	ADJ	_	Degree=Pos	_	_	_	_
40	proteins	_	NOUN	_	Number=Plur	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	infectivity	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	tumor	_	NOUN	_	Number=Sing	_	_	_	_
46	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
47	factor	_	NOUN	_	Number=Sing	_	_	_	_
48	alpha	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	present	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	model	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	replication	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	viral	_	ADJ	_	Degree=Pos	_	_	_	_
12	protease	_	NOUN	_	Number=Sing	_	_	_	_
13	depletes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	bcl	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
25	stress	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	kappa	_	PROPN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
36	factor	_	NOUN	_	Number=Sing	_	_	_	_
37	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	HIV	_	NOUN	_	Number=Sing	_	_	_	_
40	transcription	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	ultimately	_	ADV	_	_	_	_	_	_
44	to	_	PART	_	_	_	_	_	_
45	cell	_	VERB	_	VerbForm=Inf	_	_	_	_
46	death	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	bcl	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	cleaved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	protease	_	NOUN	_	Number=Sing	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	phenylalanine	_	NOUN	_	Number=Sing	_	_	_	_
12	112	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	alanine	_	NOUN	_	Number=Sing	_	_	_	_
15	113	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	new	_	ADJ	_	Degree=Pos	_	_	_	_
6	option	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	therapy	_	NOUN	_	Number=Sing	_	_	_	_
11	;	_	PUNCT	_	_	_	_	_	_
12	bcl	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	muteins	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	noncleavable	_	ADJ	_	Degree=Pos	_	_	_	_
19	alterations	_	NOUN	_	Number=Plur	_	_	_	_
20	surrounding	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	HIV	_	PROPN	_	Number=Sing	_	_	_	_
23	protease	_	NOUN	_	Number=Sing	_	_	_	_
24	cleavage	_	NOUN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011742	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differentiation	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	carboxylesterase	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Carboxylesterases	_	NOUN	_	Number=Plur	_	_	_	_
2	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	important	_	ADJ	_	Degree=Pos	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	defense	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	clearance	_	NOUN	_	Number=Sing	_	_	_	_
10	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
16	system	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	During	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
4	process	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	THP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	transient	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	carboxylesterase	_	NOUN	_	Number=Sing	_	_	_	_
25	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	means	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
30	blots	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	PMA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	THP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	could	_	AUX	_	VerbForm=Fin	_	_	_	_
11	detect	_	VERB	_	VerbForm=Inf	_	_	_	_
12	three	_	NUM	_	NumType=Card	_	_	_	_
13	major	_	ADJ	_	Degree=Pos	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	initiation	_	NOUN	_	Number=Sing	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	as	_	SCONJ	_	_	_	_	_	_
18	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	Nuclease	_	PROPN	_	Number=Sing	_	_	_	_
21	Protection	_	PROPN	_	Number=Sing	_	_	_	_
22	Assay	_	PROPN	_	Number=Sing	_	_	_	_
23	carried	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	out	_	ADV	_	_	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	two	_	NUM	_	NumType=Card	_	_	_	_
27	overlapping	_	ADJ	_	Degree=Pos	_	_	_	_
28	antisense	_	ADJ	_	Degree=Pos	_	_	_	_
29	RNA	_	PROPN	_	Number=Sing	_	_	_	_
30	probes	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	recently	_	ADV	_	_	_	_	_	_
4	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	carboxylesterase	_	NOUN	_	Number=Sing	_	_	_	_
7	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
8	sequence	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	basal	_	ADJ	_	Degree=Pos	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	CHO	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	spanning	_	VERB	_	VerbForm=Ger	_	_	_	_
13	base	_	NOUN	_	Number=Sing	_	_	_	_
14	pairs	_	NOUN	_	Number=Plur	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	-	_	SYM	_	_	_	_	_	_
19	275	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	several	_	ADJ	_	Degree=Pos	_	_	_	_
24	putative	_	ADJ	_	Degree=Pos	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	sites	_	NOUN	_	Number=Plur	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	factors	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	bound	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
35	factors	_	NOUN	_	Number=Plur	_	_	_	_
36	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	IRBP	_	PROPN	_	Number=Sing	_	_	_	_
39	but	_	CCONJ	_	_	_	_	_	_
40	not	_	ADV	_	_	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	C/EBPs	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	carboxylesterase	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	THP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	starts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
18	initiation	_	NOUN	_	Number=Sing	_	_	_	_
19	sites	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	IRBP	_	PROPN	_	Number=Sing	_	_	_	_
25	may	_	AUX	_	VerbForm=Fin	_	_	_	_
26	be	_	AUX	_	VerbForm=Inf	_	_	_	_
27	critical	_	ADJ	_	Degree=Pos	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	for	_	SCONJ	_	_	_	_	_	_
30	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
38	human	_	ADJ	_	Degree=Pos	_	_	_	_
39	carboxylesterase	_	NOUN	_	Number=Sing	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011747	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Engagement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	natural	_	ADJ	_	Degree=Pos	_	_	_	_
4	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
5	programs	_	NOUN	_	Number=Plur	_	_	_	_
6	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	AP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	NKL	_	PROPN	_	Number=Sing	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	NK	_	PROPN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	line	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	NK	_	PROPN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	fast	_	ADJ	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
9	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	target	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	lysis	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	such	_	ADJ	_	Degree=Pos	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	multiplex	_	ADJ	_	Degree=Pos	_	_	_	_
8	messenger	_	NOUN	_	Number=Sing	_	_	_	_
9	assays	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	here	_	ADV	_	PronType=Dem	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	natural	_	ADJ	_	Degree=Pos	_	_	_	_
16	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
17	exerted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	NKL	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
27	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	very	_	ADV	_	_	_	_	_	_
30	early	_	ADJ	_	Degree=Pos	_	_	_	_
31	activator	_	NOUN	_	Number=Sing	_	_	_	_
32	protein	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	AP	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	factor	_	NOUN	_	Number=Sing	_	_	_	_
40	genes	_	NOUN	_	Number=Plur	_	_	_	_
41	such	_	ADJ	_	Degree=Pos	_	_	_	_
42	as	_	ADP	_	_	_	_	_	_
43	JunB	_	PROPN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	FosB	_	NOUN	_	Number=Sing	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	activities	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Jun	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	Fos	_	PROPN	_	Number=Sing	_	_	_	_
12	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
17	mobility	_	NOUN	_	Number=Sing	_	_	_	_
18	shift	_	NOUN	_	Number=Sing	_	_	_	_
19	assays	_	NOUN	_	Number=Plur	_	_	_	_
20	during	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	course	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	natural	_	ADJ	_	Degree=Pos	_	_	_	_
25	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Interaction	_	NOUN	_	Number=Sing	_	_	_	_
2	between	_	ADP	_	_	_	_	_	_
3	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	like	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcript-2/leukocyte	_	NOUN	_	Number=Sing	_	_	_	_

1	Ig	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	like	_	ADP	_	Degree=Pos	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	NKL	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	HLA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	B27	_	NOUN	_	Number=Sing	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	target	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	impairment	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	NKL	_	PROPN	_	Number=Sing	_	_	_	_
22	natural	_	ADJ	_	Degree=Pos	_	_	_	_
23	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	absence	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	JunB	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	FosB	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	c-Fos	_	NOUN	_	Number=Sing	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	as	_	ADV	_	_	_	_	_	_
40	well	_	ADV	_	Degree=Pos	_	_	_	_
41	as	_	ADP	_	_	_	_	_	_
42	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	absence	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
46	DNA	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	binding	_	NOUN	_	Number=Sing	_	_	_	_
49	activity	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	thus	_	ADV	_	_	_	_	_	_
4	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	despite	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	rapidity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NK	_	PROPN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	lysis	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	AP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	during	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	early	_	ADJ	_	Degree=Pos	_	_	_	_
27	stage	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	NK	_	PROPN	_	Number=Sing	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	cytolytic	_	NOUN	_	Number=Sing	_	_	_	_
32	programs	_	NOUN	_	Number=Plur	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
35	engagement	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	NK	_	PROPN	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
40	receptors	_	NOUN	_	Number=Plur	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	MHC	_	PROPN	_	Number=Sing	_	_	_	_
43	class	_	NOUN	_	Number=Sing	_	_	_	_
44	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
45	molecules	_	NOUN	_	Number=Plur	_	_	_	_
46	impairs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	very	_	ADV	_	_	_	_	_	_
49	early	_	ADJ	_	Degree=Pos	_	_	_	_
50	activation	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	AP	_	NOUN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	1	_	NUM	_	NumType=Card	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_
56	Document	_	NOUN	_	Number=Sing	_	_	_	_
57	0030011751	_	NUM	_	NumType=Card	_	_	_	_
58	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Octamer	_	PROPN	_	Number=Sing	_	_	_	_
2	independent	_	ADJ	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	kappa	_	PROPN	_	Number=Sing	_	_	_	_
9	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
10	germline	_	NOUN	_	Number=Sing	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	analyses	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
5	V	_	PROPN	_	Number=Sing	_	_	_	_
6	region	_	NOUN	_	Number=Sing	_	_	_	_
7	promoters	_	NOUN	_	Number=Plur	_	_	_	_
8	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	led	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	discovery	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	common	_	ADJ	_	Degree=Pos	_	_	_	_
16	octamer	_	NOUN	_	Number=Sing	_	_	_	_
17	motif	_	NOUN	_	Number=Sing	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	functionally	_	ADV	_	_	_	_	_	_
21	important	_	ADJ	_	Degree=Pos	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	tissue	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	developmentally	_	ADV	_	_	_	_	_	_
29	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
34	genes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	germline	_	NOUN	_	Number=Sing	_	_	_	_
3	promoters	_	NOUN	_	Number=Plur	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	Ko	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	upstream	_	ADP	_	_	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	J	_	PROPN	_	Number=Sing	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	segments	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	locus	_	NOUN	_	Number=Sing	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	octamer	_	NOUN	_	Number=Sing	_	_	_	_
23	motif	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	single	_	ADJ	_	Degree=Pos	_	_	_	_
28	base	_	NOUN	_	Number=Sing	_	_	_	_
29	pair	_	NOUN	_	Number=Sing	_	_	_	_
30	mutation	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	referred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	as	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	variant	_	ADJ	_	Degree=Pos	_	_	_	_
37	octamer	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	which	_	PRON	_	PronType=Rel	_	_	_	_
40	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
42	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	previously	_	ADV	_	_	_	_	_	_
44	to	_	PART	_	_	_	_	_	_
45	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
46	Oct	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	1	_	NUM	_	NumType=Card	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	Oct	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	2	_	NUM	_	NumType=Card	_	_	_	_
53	transcription	_	NOUN	_	Number=Sing	_	_	_	_
54	factors	_	NOUN	_	Number=Plur	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	vitro	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	elucidate	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	variant	_	ADJ	_	Degree=Pos	_	_	_	_
9	octamer	_	NOUN	_	Number=Sing	_	_	_	_
10	motif	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	regulation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	germline	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	unrearranged	_	ADJ	_	Degree=Pos	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	locus	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
24	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	quantitated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	relative	_	ADJ	_	Degree=Pos	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	affinity	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	Oct	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	Oct	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	SYM	_	_	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	variant	_	ADJ	_	Degree=Pos	_	_	_	_
41	octamer	_	NOUN	_	Number=Sing	_	_	_	_
42	motif	_	NOUN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	determined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	functional	_	ADJ	_	Degree=Pos	_	_	_	_
47	role	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
50	octamer	_	NOUN	_	Number=Sing	_	_	_	_
51	motif	_	NOUN	_	Number=Sing	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
54	activation	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	although	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	variant	_	ADJ	_	Degree=Pos	_	_	_	_
8	octamer	_	NOUN	_	Number=Sing	_	_	_	_
9	motif	_	NOUN	_	Number=Sing	_	_	_	_
10	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	Oct	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	Oct	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	vitro	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	5	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
24	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
25	affinity	_	NOUN	_	Number=Sing	_	_	_	_
26	than	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	consensus	_	NOUN	_	Number=Sing	_	_	_	_
29	octamer	_	NOUN	_	Number=Sing	_	_	_	_
30	motif	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	mutation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	variant	_	ADJ	_	Degree=Pos	_	_	_	_
36	octamer	_	NOUN	_	Number=Sing	_	_	_	_
37	motif	_	NOUN	_	Number=Sing	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	either	_	CCONJ	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	consensus	_	NOUN	_	Number=Sing	_	_	_	_
42	octamer	_	NOUN	_	Number=Sing	_	_	_	_
43	or	_	CCONJ	_	_	_	_	_	_
44	non-octamer	_	ADJ	_	Number=Sing	_	_	_	_
45	motif	_	NOUN	_	Number=Sing	_	_	_	_
46	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
47	no	_	DET	_	_	_	_	_	_
48	effect	_	NOUN	_	Number=Sing	_	_	_	_
49	on	_	ADP	_	_	_	_	_	_
50	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
51	activation	_	NOUN	_	Number=Sing	_	_	_	_
52	from	_	ADP	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	germline	_	NOUN	_	Number=Sing	_	_	_	_
55	promoter	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	significant	_	ADJ	_	Degree=Pos	_	_	_	_
5	differences	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	germline	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	V	_	NOUN	_	Number=Sing	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	promoters	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	kappa	_	PROPN	_	Number=Sing	_	_	_	_
16	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	germline	_	NOUN	_	Number=Sing	_	_	_	_
7	promoters	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	V	_	NOUN	_	Number=Sing	_	_	_	_
10	region	_	NOUN	_	Number=Sing	_	_	_	_
11	promoters	_	NOUN	_	Number=Plur	_	_	_	_
12	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	dependence	_	NOUN	_	Number=Sing	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	octamer	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	respond	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	differently	_	ADV	_	_	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	important	_	ADJ	_	Degree=Pos	_	_	_	_
5	implications	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	germline	_	NOUN	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	as	_	ADV	_	_	_	_	_	_
12	well	_	ADV	_	Degree=Pos	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	V-J	_	PROPN	_	Number=Sing	_	_	_	_
19	recombination	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	kappa	_	PROPN	_	Number=Sing	_	_	_	_
23	light	_	NOUN	_	Number=Sing	_	_	_	_
24	chain	_	NOUN	_	Number=Sing	_	_	_	_
25	locus	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011752	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Recombinant	_	ADJ	_	Number=Sing	_	_	_	_
2	NFAT1	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	mediates	_	VERB	_	Number=Plur	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	several	_	ADJ	_	Degree=Pos	_	_	_	_
18	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
6	family	_	NOUN	_	Number=Sing	_	_	_	_
7	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	key	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	during	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	immune	_	ADJ	_	Degree=Pos	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	new	_	ADJ	_	Degree=Pos	_	_	_	_
6	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	NFAT1	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	previously	_	ADV	_	_	_	_	_	_
14	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	predominant	_	ADJ	_	Degree=Pos	_	_	_	_
21	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
22	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	murine	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	recombinant	_	ADJ	_	Number=Sing	_	_	_	_
9	NFAT1	_	PROPN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	as	_	SCONJ	_	_	_	_	_	_
14	expected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	calmodulin	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
21	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
22	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	function	_	NOUN	_	Number=Sing	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
32	agent	_	NOUN	_	Number=Sing	_	_	_	_
33	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
34	A	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	CsA	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Transactivation	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	recombinant	_	ADJ	_	Number=Sing	_	_	_	_
4	NFAT1	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	dual	_	ADJ	_	Degree=Pos	_	_	_	_
11	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
16	12	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	myristate	_	NOUN	_	Number=Sing	_	_	_	_
19	13	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	acetate	_	NOUN	_	Number=Sing	_	_	_	_
22	;	_	PUNCT	_	_	_	_	_	_
23	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	potentiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	coexpression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	constitutively	_	ADV	_	_	_	_	_	_
31	active	_	ADJ	_	Degree=Pos	_	_	_	_
32	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	CsA	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Immunocytochemical	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
6	NFAT1	_	NOUN	_	Number=Sing	_	_	_	_
7	localizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	transiently	_	ADV	_	_	_	_	_	_
13	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	translocates	_	VERB	_	Number=Plur	_	_	_	_
18	into	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	CsA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
26	manner	_	NOUN	_	Number=Sing	_	_	_	_
27	following	_	VERB	_	VerbForm=Ger	_	_	_	_
28	ionomycin	_	ADJ	_	Number=Sing	_	_	_	_
29	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	COS	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	however	_	ADV	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	NFAT1	_	PROPN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	capable	_	ADJ	_	Degree=Pos	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	correctly	_	ADV	_	_	_	_	_	_
21	:	_	PUNCT	_	_	_	_	_	_

1	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	s	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	subcellular	_	ADJ	_	Degree=Pos	_	_	_	_
4	localization	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	function	_	NOUN	_	Number=Sing	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	COS	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
21	12	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	myristate	_	NOUN	_	Number=Sing	_	_	_	_
24	13	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	acetate	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
2	NFAT1	_	PROPN	_	Number=Sing	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	tumor	_	NOUN	_	Number=Sing	_	_	_	_
17	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
25	colony	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	promoters	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	T	_	PROPN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
35	that	_	SCONJ	_	_	_	_	_	_
36	NFAT1	_	PROPN	_	Number=Sing	_	_	_	_
37	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	CsA	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
43	transcription	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
46	genes	_	NOUN	_	Number=Plur	_	_	_	_
47	during	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	immune	_	ADJ	_	Degree=Pos	_	_	_	_
50	response	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011759	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	bovine	_	VERB	_	Number=Sing	_	_	_	_
7	colostrum	_	NOUN	_	Number=Sing	_	_	_	_
8	blocks	_	NOUN	_	Number=Plur	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	bovine	_	VERB	_	Number=Sing	_	_	_	_
5	colostrum	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	colostrum	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	CIF	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	inhibits	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	IL2	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	production	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	helper	_	VERB	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	by	_	SCONJ	_	_	_	_	_	_
26	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	IL2	_	NOUN	_	Number=Sing	_	_	_	_
31	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	CIF	_	NOUN	_	Number=Sing	_	_	_	_
5	blocks	_	NOUN	_	Number=Plur	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	level	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IL2	_	PROPN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	introduced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	reporter	_	NOUN	_	Number=Sing	_	_	_	_
16	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
17	into	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	transient	_	ADJ	_	Degree=Pos	_	_	_	_
27	transfection	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
2	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	under	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	control	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	either	_	CCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	IL2	_	NOUN	_	Number=Sing	_	_	_	_
14	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	segments	_	NOUN	_	Number=Plur	_	_	_	_
19	-326	_	NUM	_	NumType=Card	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	+	_	SYM	_	_	_	_	_	_
22	45	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	three	_	NUM	_	NumType=Card	_	_	_	_
26	repeats	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
30	element	_	NOUN	_	Number=Sing	_	_	_	_
31	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	within	_	ADP	_	_	_	_	_	_
33	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	segments	_	NOUN	_	Number=Plur	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	255	_	NUM	_	NumType=Card	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	-	_	SYM	_	_	_	_	_	_
40	285	_	NUM	_	NumType=Card	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
11	myristate	_	NOUN	_	Number=Sing	_	_	_	_
12	acetate	_	NOUN	_	Number=Sing	_	_	_	_
13	plus	_	CCONJ	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	calcium	_	NOUN	_	Number=Sing	_	_	_	_
16	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	CIF	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	either	_	CCONJ	_	_	_	_	_	_
6	construct	_	NOUN	_	Number=Sing	_	_	_	_
7	as	_	SCONJ	_	_	_	_	_	_
8	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	cyclosporine	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	block	_	VERB	_	VerbForm=Inf	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
20	element	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	CIF	_	PROPN	_	Number=Sing	_	_	_	_
2	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
5	several	_	ADJ	_	Degree=Pos	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	elements	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	system	_	NOUN	_	Number=Sing	_	_	_	_
8	distinguishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	CIF	_	PROPN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	other	_	ADJ	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	NumType=Card	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
15	activities	_	NOUN	_	Number=Plur	_	_	_	_
16	present	_	VERB	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	colostrum	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	particular	_	ADJ	_	Degree=Pos	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	TGF	_	PROPN	_	Number=Sing	_	_	_	_
24	beta	_	NOUN	_	Number=Sing	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	TGF	_	PROPN	_	Number=Sing	_	_	_	_
28	beta	_	NOUN	_	Number=Sing	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Stably	_	ADV	_	_	_	_	_	_
2	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_

1	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	behaved	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	similarly	_	ADV	_	_	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	transiently	_	ADV	_	_	_	_	_	_
8	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	ones	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	respect	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	CIF	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	cyclosporine	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	luc	_	NOUN	_	Number=Sing	_	_	_	_
5	assay	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	useful	_	ADJ	_	Degree=Pos	_	_	_	_
9	technique	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
15	measurement	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	CIF	_	NOUN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	other	_	ADJ	_	Degree=Pos	_	_	_	_
20	immunosuppressants	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	similar	_	ADJ	_	Degree=Pos	_	_	_	_
24	mode	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	action	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011762	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Phenylarsine	_	PROPN	_	Number=Sing	_	_	_	_
2	oxide	_	NOUN	_	Number=Sing	_	_	_	_
3	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
4	ex	_	NOUN	_	Number=Sing	_	_	_	_
5	vivo	_	NUM	_	Number=Sing	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Phenylarsine	_	PROPN	_	Number=Sing	_	_	_	_
2	oxide	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	PAO	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	tyrosine	_	ADJ	_	Number=Sing	_	_	_	_
15	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
20	release	_	NOUN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
24	blood	_	NOUN	_	Number=Sing	_	_	_	_
25	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	PBMCs	_	NOUN	_	Number=Plur	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	as	_	SCONJ	_	_	_	_	_	_
31	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	electrochemistry	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	replication	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	favored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	under	_	ADP	_	_	_	_	_	_
19	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
20	stress	_	NOUN	_	Number=Sing	_	_	_	_
21	conditions	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	ex	_	NOUN	_	Number=Sing	_	_	_	_
24	vivo	_	NOUN	_	Degree=Pos	_	_	_	_
25	experiments	_	NOUN	_	Number=Plur	_	_	_	_
26	using	_	VERB	_	VerbForm=Ger	_	_	_	_
27	uninfected	_	ADJ	_	Degree=Pos	_	_	_	_
28	PBMCs	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	primary	_	ADJ	_	Degree=Pos	_	_	_	_
31	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	latently	_	ADV	_	_	_	_	_	_
35	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
37	U1	_	PROPN	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	line	_	NOUN	_	Number=Sing	_	_	_	_
40	show	_	VERB	_	Number=Sing	_	_	_	_
41	that	_	SCONJ	_	_	_	_	_	_
42	HIV	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	replication	_	NOUN	_	Number=Sing	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	reactivation	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	monitored	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	by	_	ADP	_	_	_	_	_	_
51	p24	_	NUM	_	Number=Sing	_	_	_	_
52	antigen	_	NOUN	_	Degree=Pos	_	_	_	_
53	measurement	_	NOUN	_	Number=Sing	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
56	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
57	by	_	ADP	_	_	_	_	_	_
58	PAO	_	NOUN	_	Number=Sing	_	_	_	_
59	in	_	ADP	_	_	_	_	_	_
60	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
61	time	_	NOUN	_	Number=Sing	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	and	_	CCONJ	_	_	_	_	_	_
64	concentration	_	NOUN	_	Number=Sing	_	_	_	_
65	-	_	PUNCT	_	_	_	_	_	_
66	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
67	manner	_	NOUN	_	Number=Sing	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	when	_	ADV	_	PronType=Int	_	_	_	_
16	uninfected	_	ADJ	_	Degree=Pos	_	_	_	_
17	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	either	_	CCONJ	_	_	_	_	_	_
22	tumor	_	NOUN	_	Number=Sing	_	_	_	_
23	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	TNF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
32	12	_	NUM	_	NumType=Card	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	myristate	_	NOUN	_	Number=Sing	_	_	_	_
35	13	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	acetate	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	PMA	_	PROPN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	or	_	CCONJ	_	_	_	_	_	_
42	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	LPS	_	NOUN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011776	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tissue	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	gammac	_	PROPN	_	Number=Sing	_	_	_	_
8	chain	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	upon	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	Ets	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	GA	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	binding	_	VERB	_	Number=Sing	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	gammac	_	NOUN	_	Number=Sing	_	_	_	_
3	chain	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	subunit	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	receptors	_	NOUN	_	Number=Plur	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	7	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	9	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	15	_	NUM	_	NumType=Card	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	which	_	PRON	_	PronType=Rel	_	_	_	_
41	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
45	lineages	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	defect	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	gammac	_	NOUN	_	Number=Sing	_	_	_	_
5	leads	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	X	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	severe	_	ADJ	_	Degree=Pos	_	_	_	_
12	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
14	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	block	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	better	_	ADV	_	Degree=Cmp	_	_	_	_
5	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	gammac	_	NOUN	_	Number=Sing	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	define	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
14	tissue	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	region	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	progressive	_	ADJ	_	Degree=Pos	_	_	_	_
21	5'-	_	NUM	_	_	_	_	_	_
22	deletion	_	NOUN	_	Number=Sing	_	_	_	_
23	constructs	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	segment	_	NOUN	_	Number=Sing	_	_	_	_
27	extending	_	VERB	_	VerbForm=Ger	_	_	_	_
28	1053	_	NUM	_	NumType=Card	_	_	_	_
29	base	_	NOUN	_	Number=Sing	_	_	_	_
30	pairs	_	NOUN	_	Number=Plur	_	_	_	_
31	upstream	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	major	_	ADJ	_	Degree=Pos	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	start	_	NOUN	_	Number=Sing	_	_	_	_
37	site	_	NOUN	_	Number=Sing	_	_	_	_
38	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
39	generated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	for	_	ADP	_	_	_	_	_	_
43	promoter	_	NOUN	_	Degree=Pos	_	_	_	_
44	activity	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	various	_	ADJ	_	Degree=Pos	_	_	_	_
47	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	nonhematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
50	cell	_	NOUN	_	Number=Sing	_	_	_	_
51	types	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1053/+34	_	NUM	_	NumType=Card	_	_	_	_
4	construct	_	NOUN	_	Number=Sing	_	_	_	_
5	allowed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	only	_	ADV	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
13	origin	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	tissue	_	NOUN	_	Number=Sing	_	_	_	_
17	specificity	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	conserved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	all	_	DET	_	_	_	_	_	_
22	other	_	ADJ	_	Degree=Pos	_	_	_	_
23	constructs	_	NOUN	_	Number=Plur	_	_	_	_
24	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	downstream	_	NOUN	_	Degree=Pos	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	90	_	NUM	_	NumType=Card	_	_	_	_
7	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	critical	_	ADJ	_	Degree=Pos	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	basal	_	ADJ	_	Degree=Pos	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	two	_	NUM	_	NumType=Card	_	_	_	_
4	potential	_	ADJ	_	Degree=Pos	_	_	_	_
5	Ets	_	NOUN	_	Number=Plur	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	murine	_	NOUN	_	Number=Sing	_	_	_	_
12	gammac	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	one	_	NUM	_	NumType=Card	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Int	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	essential	_	ADJ	_	Degree=Pos	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	functional	_	ADJ	_	Degree=Pos	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	as	_	SCONJ	_	_	_	_	_	_
27	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	mutational	_	ADJ	_	Degree=Pos	_	_	_	_
30	analysis	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	functional	_	ADJ	_	Degree=Pos	_	_	_	_
3	Ets	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
10	Ets	_	NOUN	_	Number=Sing	_	_	_	_
11	family	_	NOUN	_	Number=Sing	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	principally	_	ADV	_	_	_	_	_	_
15	GA	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	Elf	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	could	_	AUX	_	VerbForm=Fin	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	transactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	GABPalpha	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	beta	_	NOUN	_	Number=Sing	_	_	_	_
32	synergistically	_	ADV	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	as	_	SCONJ	_	_	_	_	_	_
7	already	_	ADV	_	_	_	_	_	_
8	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	IL2Rbeta	_	PROPN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	GA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	essential	_	ADJ	_	Degree=Pos	_	_	_	_
21	component	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	gammac	_	ADJ	_	Number=Sing	_	_	_	_
24	basal	_	ADJ	_	Degree=Pos	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	GABP	_	NOUN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
10	lineage	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	interaction	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	other	_	ADJ	_	Degree=Pos	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	may	_	AUX	_	VerbForm=Fin	_	_	_	_
19	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	tissue	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	gammac	_	ADJ	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011779	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
8	molecule	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
18	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
19	virus	_	NOUN	_	Number=Sing	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	Tax	_	NOUN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Recruitment	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	extravasation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	through	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	blood	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	brain	_	NOUN	_	Number=Sing	_	_	_	_
12	barrier	_	NOUN	_	Number=Sing	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	favored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
17	molecule	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
20	interactions	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	SCONJ	_	_	_	_	_	_
22	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	common	_	ADJ	_	Degree=Pos	_	_	_	_
4	pathological	_	ADJ	_	Degree=Pos	_	_	_	_
5	finding	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
9	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	type	_	NOUN	_	Number=Sing	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	diseases	_	NOUN	_	Number=Plur	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	infiltration	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1-infected	_	VERB	_	Degree=Pos	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	into	_	ADP	_	_	_	_	_	_
31	various	_	ADJ	_	Degree=Pos	_	_	_	_
32	organs	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
35	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	looked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	profile	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
42	molecules	_	NOUN	_	Number=Plur	_	_	_	_
43	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	by	_	ADP	_	_	_	_	_	_
45	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	T	_	NOUN	_	Number=Sing	_	_	_	_
51	cells	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Flow	_	PROPN	_	Number=Sing	_	_	_	_
2	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	expressing	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
10	high	_	ADJ	_	Degree=Pos	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
16	molecule	_	NOUN	_	Number=Sing	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	[	_	PUNCT	_	_	_	_	_	_
23	CD106	_	NOUN	_	Number=Sing	_	_	_	_
24	]	_	PUNCT	_	_	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	110	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kDa	_	NOUN	_	Number=Sing	_	_	_	_
31	member	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	first	_	ADV	_	_	_	_	_	_
39	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	on	_	ADP	_	_	_	_	_	_
41	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	with	_	ADP	_	_	_	_	_	_
45	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
46	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
3	molecule	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	one	_	NUM	_	NumType=Card	_	_	_	_
13	patient	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	myelopathy	_	NOUN	_	Degree=Pos	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	tropical	_	ADJ	_	Degree=Pos	_	_	_	_
23	spastic	_	ADJ	_	Degree=Pos	_	_	_	_
24	paraparesis	_	NOUN	_	Number=Sing	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	T	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	one	_	NUM	_	NumType=Card	_	_	_	_
34	normal	_	ADJ	_	Degree=Pos	_	_	_	_
35	blood	_	NOUN	_	Number=Sing	_	_	_	_
36	donor	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	viral	_	ADJ	_	Degree=Pos	_	_	_	_
6	trans	_	NOUN	_	Number=Plur	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	activator	_	NOUN	_	Number=Sing	_	_	_	_
9	Tax	_	NOUN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	first	_	ADV	_	_	_	_	_	_
20	indicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	detection	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
27	molecule	_	NOUN	_	Number=Sing	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
30	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
31	clones	_	NOUN	_	Number=Plur	_	_	_	_
32	stably	_	ADV	_	_	_	_	_	_
33	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	tax	_	NOUN	_	Number=Sing	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Tax	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	next	_	ADV	_	_	_	_	_	_
13	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	JPX	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	9	_	NUM	_	NumType=Card	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	subclone	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	tax	_	NOUN	_	Number=Sing	_	_	_	_
29	sequences	_	NOUN	_	Number=Plur	_	_	_	_
30	under	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	control	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	deletion	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	mutation	_	NOUN	_	Number=Sing	_	_	_	_
6	analyses	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	performed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	chloramphenicol	_	NOUN	_	Number=Sing	_	_	_	_
16	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
17	constructs	_	NOUN	_	Number=Plur	_	_	_	_
18	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	Tax	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	trans	_	NOUN	_	Number=Plur	_	_	_	_
23	activating	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	via	_	ADP	_	_	_	_	_	_
30	two	_	NUM	_	NumType=Card	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	sites	_	NOUN	_	Number=Plur	_	_	_	_
35	present	_	VERB	_	Degree=Pos	_	_	_	_
36	at	_	ADP	_	_	_	_	_	_
37	bp	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	72	_	NUM	_	NumType=Card	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	-	_	SYM	_	_	_	_	_	_
42	57	_	NUM	_	NumType=Card	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	gene	_	NOUN	_	Number=Sing	_	_	_	_
49	promoter	_	NOUN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	with	_	SCONJ	_	_	_	_	_	_
52	both	_	DET	_	_	_	_	_	_
53	of	_	ADP	_	_	_	_	_	_
54	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
55	being	_	AUX	_	VerbForm=Ger	_	_	_	_
56	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
57	for	_	ADP	_	_	_	_	_	_
58	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
59	Tax	_	NOUN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
62	expression	_	NOUN	_	Number=Sing	_	_	_	_
63	of	_	ADP	_	_	_	_	_	_
64	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
65	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
66	molecule	_	NOUN	_	Number=Sing	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	gel	_	NOUN	_	Number=Sing	_	_	_	_
4	mobility	_	NOUN	_	Number=Sing	_	_	_	_
5	shift	_	NOUN	_	Number=Sing	_	_	_	_
6	assays	_	NOUN	_	Number=Plur	_	_	_	_
7	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	translocation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	specifically	_	ADV	_	_	_	_	_	_
14	bound	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	motifs	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	confirming	_	VERB	_	VerbForm=Ger	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	on	_	ADP	_	_	_	_	_	_
31	Tax	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
40	manner	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Collectively	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	therefore	_	ADV	_	_	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	exclusive	_	ADJ	_	Degree=Pos	_	_	_	_
10	Tax	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	may	_	AUX	_	VerbForm=Fin	_	_	_	_
22	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	pivotal	_	ADJ	_	Degree=Pos	_	_	_	_
25	event	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	progression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	diseases	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011783	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Rel	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	control	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	process	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	eliminate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	unwanted	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	wide	_	ADJ	_	Degree=Pos	_	_	_	_
14	variety	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	organisms	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Various	_	ADJ	_	Degree=Pos	_	_	_	_
2	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	signals	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	often	_	ADV	_	_	_	_	_	_
6	converging	_	VERB	_	VerbForm=Ger	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	common	_	ADJ	_	Degree=Pos	_	_	_	_
9	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	pathways	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
14	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	type	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	specific	_	ADJ	_	Degree=Pos	_	_	_	_
22	fashion	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	work	_	NOUN	_	Number=Sing	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	several	_	ADJ	_	Degree=Pos	_	_	_	_
5	laboratories	_	NOUN	_	Number=Plur	_	_	_	_
6	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	Rel	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	many	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	types	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	most	_	ADJ	_	Degree=Sup	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	Rel	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	survival	_	NOUN	_	Number=Sing	_	_	_	_
17	signals	_	NOUN	_	Number=Plur	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	protect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
23	;	_	PUNCT	_	_	_	_	_	_
24	however	_	ADV	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	under	_	ADP	_	_	_	_	_	_
27	some	_	DET	_	_	_	_	_	_
28	circumstances	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
33	factors	_	NOUN	_	Number=Plur	_	_	_	_
34	may	_	AUX	_	VerbForm=Fin	_	_	_	_
35	also	_	ADV	_	_	_	_	_	_
36	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
37	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011790	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Reactive	_	ADJ	_	Degree=Pos	_	_	_	_
2	oxygen	_	ADJ	_	Degree=Pos	_	_	_	_
3	species	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	diseases	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	paper	_	NOUN	_	Number=Sing	_	_	_	_
3	aims	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	review	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	free	_	ADJ	_	Degree=Pos	_	_	_	_
10	radical	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	tissue	_	NOUN	_	Number=Sing	_	_	_	_
14	damage	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
17	defence	_	NOUN	_	Number=Sing	_	_	_	_
18	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	diseases	_	NOUN	_	Number=Plur	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	involve	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	pathogenic	_	ADJ	_	Degree=Pos	_	_	_	_
25	processes	_	NOUN	_	Number=Plur	_	_	_	_
26	similar	_	ADJ	_	Degree=Pos	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	periodontal	_	ADJ	_	Degree=Pos	_	_	_	_
30	diseases	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	clearly	_	ADV	_	_	_	_	_	_
5	defined	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	free	_	ADJ	_	Degree=Pos	_	_	_	_
11	radicals	_	NOUN	_	Number=Plur	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
14	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
15	species	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	ROS	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	periodontitis	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	little	_	ADJ	_	Degree=Pos	_	_	_	_
24	research	_	NOUN	_	Number=Sing	_	_	_	_
25	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
27	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	area	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	paper	_	NOUN	_	Number=Sing	_	_	_	_
3	reviews	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	considerable	_	ADJ	_	Degree=Pos	_	_	_	_
6	data	_	NOUN	_	Number=Sing	_	_	_	_
7	available	_	ADJ	_	Degree=Pos	_	_	_	_
8	relating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	ROS	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
13	defence	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	diseases	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	attempts	_	NOUN	_	Number=Plur	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	draw	_	VERB	_	VerbForm=Inf	_	_	_	_
21	parallels	_	NOUN	_	Number=Plur	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	periodontitis	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	effort	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
30	more	_	ADJ	_	Degree=Cmp	_	_	_	_
31	periodontal	_	ADJ	_	Degree=Pos	_	_	_	_
32	research	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
35	important	_	ADJ	_	Degree=Pos	_	_	_	_
36	area	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	recent	_	ADJ	_	Degree=Pos	_	_	_	_
3	discovery	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	reviewed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	several	_	ADJ	_	Degree=Pos	_	_	_	_
22	potential	_	ADJ	_	Degree=Pos	_	_	_	_
23	pathways	_	NOUN	_	Number=Plur	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	periodontal	_	ADJ	_	Degree=Pos	_	_	_	_
29	tissue	_	NOUN	_	Number=Sing	_	_	_	_
30	damage	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappa	_	NOUN	_	Number=Sing	_	_	_	_
37	B1	_	NOUN	_	Number=Sing	_	_	_	_
38	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Emphasis	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	placed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
9	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	periodontitis	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	principally	_	ADV	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	6	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	8	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	beta-interferon	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	link	_	NOUN	_	Number=Sing	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	production	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	such	_	ADJ	_	Degree=Pos	_	_	_	_
8	important	_	ADJ	_	Degree=Pos	_	_	_	_
9	mediators	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	AO	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	thiols	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	GSH	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	hypothesised	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	that	_	SCONJ	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	antagonists	_	NOUN	_	Number=Plur	_	_	_	_
40	may	_	AUX	_	VerbForm=Fin	_	_	_	_
41	offer	_	VERB	_	VerbForm=Inf	_	_	_	_
42	important	_	ADJ	_	Degree=Pos	_	_	_	_
43	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
44	benefits	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011791	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	interferon	_	NOUN	_	Number=Sing	_	_	_	_
4	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	family	_	NOUN	_	Number=Sing	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	ICSAT	_	PROPN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	Pip	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	LSIRF	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	negatively	_	ADV	_	_	_	_	_	_
18	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	interferon	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	genes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	novel	_	NOUN	_	Number=Sing	_	_	_	_
6	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
7	clone	_	NOUN	_	Number=Sing	_	_	_	_
8	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
9	interferon	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	IFN	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	consensus	_	NOUN	_	Number=Sing	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	adult	_	NOUN	_	Number=Sing	_	_	_	_
20	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
21	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	ICSAT	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	;	_	PUNCT	_	_	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	protein	_	NOUN	_	Number=Sing	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	human	_	ADJ	_	Degree=Pos	_	_	_	_
37	homolog	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	recently	_	ADV	_	_	_	_	_	_
41	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	Pip	_	NOUN	_	Number=Sing	_	_	_	_
43	/	_	PUNCT	_	_	_	_	_	_
44	LSIRF	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	ICSAT	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	structurally	_	ADV	_	_	_	_	_	_
4	most	_	ADV	_	_	_	_	_	_
5	closely	_	ADV	_	_	_	_	_	_
6	related	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	previously	_	ADV	_	_	_	_	_	_
10	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	ICSBP	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	member	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	IFN	_	PROPN	_	Number=Sing	_	_	_	_
18	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	IRF	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	family	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	proteins	_	NOUN	_	Number=Plur	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	interferon	_	VERB	_	VerbForm=Inf	_	_	_	_
30	consensus	_	NOUN	_	Number=Sing	_	_	_	_
31	sequences	_	NOUN	_	Number=Plur	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	ICSs	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	many	_	ADJ	_	Degree=Pos	_	_	_	_
38	promoters	_	NOUN	_	Number=Plur	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	IFN	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	regulated	_	VERB	_	Degree=Pos	_	_	_	_
44	genes	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Among	_	ADP	_	_	_	_	_	_
2	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	ICSAT	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	abundantly	_	ADV	_	_	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
13	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	type	_	NOUN	_	Number=Sing	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	tax	_	NOUN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	expressed	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
12	myristake	_	NOUN	_	Number=Sing	_	_	_	_
13	acetate	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	A23187	_	NOUN	_	Number=Sing	_	_	_	_
16	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	ICSAT	_	ADJ	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	otherwise	_	ADV	_	_	_	_	_	_
29	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	not	_	PART	_	_	_	_	_	_
31	express	_	VERB	_	VerbForm=Inf	_	_	_	_
32	ICSAT	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	ICSAT	_	PROPN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	four	_	NUM	_	NumType=Card	_	_	_	_
8	different	_	ADJ	_	Degree=Pos	_	_	_	_
9	ICSs	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	tested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	relative	_	ADJ	_	Degree=Pos	_	_	_	_
15	differences	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
18	affinities	_	NOUN	_	Number=Plur	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	ICSs	_	NOUN	_	Number=Plur	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	determined	_	ADJ	_	Degree=Pos	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	study	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	functional	_	ADJ	_	Degree=Pos	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	ICSAT	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	performed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
12	experiments	_	NOUN	_	Number=Plur	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	embryonal	_	ADJ	_	Degree=Pos	_	_	_	_
17	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	line	_	NOUN	_	Number=Sing	_	_	_	_
20	N	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	Tera2	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	ICSAT	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	possess	_	VERB	_	VerbForm=Inf	_	_	_	_
6	repressive	_	ADJ	_	Degree=Pos	_	_	_	_
7	function	_	NOUN	_	Number=Sing	_	_	_	_
8	over	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	IFN	_	PROPN	_	Number=Sing	_	_	_	_
15	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	IRF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Such	_	ADJ	_	_	_	_	_	_
2	repressive	_	ADJ	_	Degree=Pos	_	_	_	_
3	function	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	similar	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
8	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	IRF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	ICSBP	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	ICSAT	_	PROPN	_	Number=Sing	_	_	_	_
8	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	different	_	ADJ	_	Degree=Pos	_	_	_	_
11	repressive	_	ADJ	_	Degree=Pos	_	_	_	_
12	effect	_	NOUN	_	Number=Sing	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IRF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	ICSBP	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	some	_	DET	_	_	_	_	_	_
23	IFN	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
26	reporter	_	NOUN	_	Number=Sing	_	_	_	_
27	constructs	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	novel	_	NOUN	_	Number=Sing	_	_	_	_
7	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	"	_	PUNCT	_	_	_	_	_	_
13	differential	_	ADJ	_	Degree=Pos	_	_	_	_
14	repression	_	NOUN	_	Number=Sing	_	_	_	_
15	"	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
20	members	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	repressor	_	NOUN	_	Number=Sing	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	different	_	ADJ	_	Degree=Pos	_	_	_	_
26	repressive	_	ADJ	_	Degree=Pos	_	_	_	_
27	effects	_	NOUN	_	Number=Plur	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	IFN	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
33	genes	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011794	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	during	_	ADP	_	_	_	_	_	_
4	myelopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	coordinated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	production	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	all	_	DET	_	_	_	_	_	_
6	blood	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	common	_	ADJ	_	Degree=Pos	_	_	_	_
11	stem	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	highly	_	ADV	_	_	_	_	_	_
16	regulated	_	ADJ	_	Degree=Pos	_	_	_	_
17	process	_	NOUN	_	Number=Sing	_	_	_	_
18	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
19	successive	_	ADJ	_	Degree=Pos	_	_	_	_
20	stages	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	commitment	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	From	_	ADP	_	_	_	_	_	_
2	analyses	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	mice	_	NOUN	_	Number=Plur	_	_	_	_
5	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	characterizations	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	chromosome	_	NOUN	_	Degree=Pos	_	_	_	_
16	breakpoints	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	leukemias	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	become	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	evident	_	ADJ	_	Degree=Pos	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	factors	_	NOUN	_	Number=Plur	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	important	_	ADJ	_	Degree=Pos	_	_	_	_
30	regulators	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	During	_	ADP	_	_	_	_	_	_
2	myelopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	development	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	lineages	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	several	_	ADJ	_	Degree=Pos	_	_	_	_
18	families	_	NOUN	_	Number=Plur	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	active	_	ADJ	_	Degree=Pos	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	including	_	VERB	_	VerbForm=Ger	_	_	_	_
23	AML1	_	PROPN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	CBF	_	PROPN	_	Number=Sing	_	_	_	_
26	beta	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	Ets	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	c-Myb	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	HOX	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	MZF	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Few	_	NOUN	_	Degree=Pos	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	exclusively	_	ADV	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	;	_	PUNCT	_	_	_	_	_	_
12	instead	_	ADV	_	_	_	_	_	_
13	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
14	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
17	cooperatively	_	ADV	_	_	_	_	_	_
18	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	discuss	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	recent	_	ADJ	_	Degree=Pos	_	_	_	_
5	advances	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	myelopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011795	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Rel	_	PROPN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	viral	_	ADJ	_	Degree=Pos	_	_	_	_
13	oncogenesis	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	viral	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Rel	_	PROPN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	consists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
11	polypeptide	_	NOUN	_	Degree=Pos	_	_	_	_
12	subunits	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	subject	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	complex	_	ADJ	_	VerbForm=Inf	_	_	_	_
19	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
20	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	involve	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	interactions	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	ubiquitination	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
33	degradation	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	nucleocytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
37	translocation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	sophisticated	_	ADJ	_	Degree=Pos	_	_	_	_
3	control	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Rel	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	surprising	_	ADJ	_	Degree=Pos	_	_	_	_
15	since	_	SCONJ	_	_	_	_	_	_
16	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	involved	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	wide	_	ADJ	_	Degree=Pos	_	_	_	_
24	array	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
27	responses	_	NOUN	_	Number=Plur	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
30	cues	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	growth	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	development	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	pathogen	_	NOUN	_	Degree=Pos	_	_	_	_
42	invasion	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	unexpected	_	ADJ	_	Degree=Pos	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	versatile	_	ADJ	_	Degree=Pos	_	_	_	_
10	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	homeostatic	_	ADJ	_	Number=Sing	_	_	_	_
12	switch	_	NOUN	_	Number=Sing	_	_	_	_
13	would	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	variety	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	viral	_	ADJ	_	Degree=Pos	_	_	_	_
21	pathogens	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	evolved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	utilize	_	VERB	_	VerbForm=Inf	_	_	_	_
29	various	_	ADJ	_	Degree=Pos	_	_	_	_
30	aspects	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	Rel	_	NOUN	_	Number=Sing	_	_	_	_
33	/	_	PUNCT	_	_	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappa	_	NOUN	_	Number=Sing	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	activity	_	NOUN	_	Number=Sing	_	_	_	_
39	to	_	PART	_	_	_	_	_	_
40	facilitate	_	VERB	_	VerbForm=Inf	_	_	_	_
41	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
42	replication	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	cell	_	NOUN	_	Number=Sing	_	_	_	_
45	survival	_	NOUN	_	Number=Sing	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	possibly	_	ADV	_	_	_	_	_	_
48	evasion	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	immune	_	ADJ	_	Number=Sing	_	_	_	_
51	responses	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	review	_	NOUN	_	Number=Sing	_	_	_	_
3	will	_	AUX	_	VerbForm=Fin	_	_	_	_
4	cover	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	utilized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
13	oncogenic	_	ADJ	_	Degree=Pos	_	_	_	_
14	viruses	_	NOUN	_	Number=Plur	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Rel	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	factors	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	role	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	Rel	_	PROPN	_	Number=Sing	_	_	_	_
33	/	_	PUNCT	_	_	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappa	_	NOUN	_	Number=Sing	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	regulation	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	viral	_	ADJ	_	Degree=Pos	_	_	_	_
43	gene	_	NOUN	_	Number=Sing	_	_	_	_
44	expression	_	NOUN	_	Number=Sing	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	replication	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011800	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cyclooxygenase	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	trifluoromethyl	_	NOUN	_	Number=Sing	_	_	_	_
11	derivatives	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	triflusal	_	ADJ	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	deacetylated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
20	metabolite	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	hydroxy-4	_	NUM	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	trifluoromethylbenzoic	_	ADJ	_	Degree=Pos	_	_	_	_
27	acid	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
3	potential	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	drugs	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	block	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cyclooxygenase	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	emphasized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	trifluoromethyl	_	NOUN	_	Degree=Pos	_	_	_	_
6	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
7	derivatives	_	NOUN	_	Number=Plur	_	_	_	_
8	[	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	acetoxy-4	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	trifluoromethyl-benzoic	_	ADJ	_	Degree=Pos	_	_	_	_
14	acid	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	triflusal	_	ADJ	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	deacetylated	_	ADJ	_	Degree=Pos	_	_	_	_
21	metabolite	_	NOUN	_	Number=Sing	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	hydroxy-4-trifluoromethylbenzoic	_	ADJ	_	Degree=Pos	_	_	_	_
25	acid	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	HTB	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	]	_	PUNCT	_	_	_	_	_	_
30	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	sodium	_	NOUN	_	Number=Sing	_	_	_	_
36	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
37	as	_	ADP	_	_	_	_	_	_
38	cyclooxygenase	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	2	_	NUM	_	NumType=Card	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	COX	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	2	_	NUM	_	NumType=Card	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
49	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
50	that	_	SCONJ	_	_	_	_	_	_
51	in	_	ADP	_	_	_	_	_	_
52	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
53	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
56	human	_	ADJ	_	Degree=Pos	_	_	_	_
57	blood	_	NOUN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	triflusal	_	NOUN	_	Number=Sing	_	_	_	_
60	,	_	PUNCT	_	_	_	_	_	_
61	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	and	_	CCONJ	_	_	_	_	_	_
64	HTB	_	PROPN	_	Number=Sing	_	_	_	_
65	,	_	PUNCT	_	_	_	_	_	_
66	but	_	CCONJ	_	_	_	_	_	_
67	not	_	ADV	_	_	_	_	_	_
68	sodium	_	NOUN	_	Number=Sing	_	_	_	_
69	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
70	,	_	PUNCT	_	_	_	_	_	_
71	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
72	COX	_	PROPN	_	Number=Sing	_	_	_	_
73	-	_	PUNCT	_	_	_	_	_	_
74	2	_	NUM	_	NumType=Card	_	_	_	_
75	-	_	PUNCT	_	_	_	_	_	_
76	mediated	_	VERB	_	Degree=Pos	_	_	_	_
77	prostaglandin	_	NOUN	_	Number=Sing	_	_	_	_
78	E2	_	NOUN	_	Number=Sing	_	_	_	_
79	(	_	PUNCT	_	_	_	_	_	_
80	PGE2	_	NOUN	_	Number=Sing	_	_	_	_
81	)	_	PUNCT	_	_	_	_	_	_
82	production	_	NOUN	_	Number=Sing	_	_	_	_
83	(	_	PUNCT	_	_	_	_	_	_
84	IC50	_	NOUN	_	Number=Sing	_	_	_	_
85	=	_	SYM	_	_	_	_	_	_
86	0.16	_	NUM	_	NumType=Card	_	_	_	_
87	,	_	PUNCT	_	_	_	_	_	_
88	0.18	_	NUM	_	NumType=Card	_	_	_	_
89	,	_	PUNCT	_	_	_	_	_	_
90	0.39	_	NUM	_	NumType=Card	_	_	_	_
91	,	_	PUNCT	_	_	_	_	_	_
92	and	_	CCONJ	_	_	_	_	_	_
93	>	_	SYM	_	_	_	_	_	_
94	10	_	NUM	_	NumType=Card	_	_	_	_
95	mM	_	NOUN	_	Number=Sing	_	_	_	_
96	,	_	PUNCT	_	_	_	_	_	_
97	respectively	_	ADV	_	_	_	_	_	_
98	)	_	PUNCT	_	_	_	_	_	_
99	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	only	_	ADV	_	_	_	_	_	_
4	triflusal	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	aspirin	_	PROPN	_	Number=Sing	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	COX	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	test	_	VERB	_	VerbForm=Inf	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
5	discrepancy	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	realized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	HTB	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	triflusal	_	PROPN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	neither	_	CCONJ	_	_	_	_	_	_
16	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
17	nor	_	CCONJ	_	_	_	_	_	_
18	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	concentration	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
25	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	COX	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	protein	_	NOUN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
34	human	_	ADJ	_	Degree=Pos	_	_	_	_
35	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	observation	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	further	_	ADV	_	_	_	_	_	_
5	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	rat	_	NOUN	_	Number=Sing	_	_	_	_
9	air	_	NOUN	_	Number=Sing	_	_	_	_
10	pouch	_	NOUN	_	Number=Sing	_	_	_	_
11	model	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vivo	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	triflusal	_	ADJ	_	Degree=Pos	_	_	_	_
21	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	ID50	_	NUM	_	Number=Sing	_	_	_	_
26	=	_	SYM	_	_	_	_	_	_
27	18.9	_	NUM	_	NumType=Card	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	11.4	_	NUM	_	NumType=Card	_	_	_	_
30	mg	_	NUM	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	kg	_	NOUN	_	Number=Sing	_	_	_	_
33	p.o.	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	respectively	_	ADV	_	_	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	but	_	CCONJ	_	_	_	_	_	_
38	only	_	ADV	_	_	_	_	_	_
39	triflusal	_	ADJ	_	Degree=Pos	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	animals	_	NOUN	_	Number=Plur	_	_	_	_
43	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
44	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
45	decrease	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	COX	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	2	_	NUM	_	NumType=Card	_	_	_	_
50	expression	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	different	_	ADJ	_	Degree=Pos	_	_	_	_
3	behavior	_	NOUN	_	Number=Sing	_	_	_	_
4	may	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	at	_	ADV	_	_	_	_	_	_
8	least	_	ADV	_	Degree=Sup	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	part	_	ADJ	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	due	_	ADP	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	ability	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	HTB	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	triflusal	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	block	_	VERB	_	VerbForm=Inf	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
35	extent	_	NOUN	_	Number=Sing	_	_	_	_
36	than	_	ADP	_	_	_	_	_	_
37	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	sodium	_	NOUN	_	Number=Sing	_	_	_	_
40	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	addition	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	COX	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
14	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	triflusal	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	able	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	block	_	VERB	_	VerbForm=Inf	_	_	_	_
21	through	_	ADP	_	_	_	_	_	_
22	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	metabolite	_	NOUN	_	Number=Sing	_	_	_	_
24	HTB	_	PROPN	_	Number=Sing	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	new	_	ADJ	_	Degree=Pos	_	_	_	_
29	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	hence	_	ADV	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	resumption	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	PGE2	_	NOUN	_	Number=Sing	_	_	_	_
37	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Triflusal	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	HTB	_	PROPN	_	Number=Sing	_	_	_	_
4	may	_	AUX	_	VerbForm=Fin	_	_	_	_
5	exert	_	VERB	_	VerbForm=Inf	_	_	_	_
6	beneficial	_	ADJ	_	Degree=Pos	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	processes	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	de	_	PROPN	_	Number=Sing	_	_	_	_
13	novo	_	PROPN	_	Number=Sing	_	_	_	_
14	COX	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	involved	_	ADJ	_	Degree=Pos	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	broader	_	ADJ	_	Degree=Pos	_	_	_	_
25	sense	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	pathological	_	ADJ	_	Degree=Pos	_	_	_	_
29	situations	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	which	_	DET	_	PronType=Rel	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	under	_	ADP	_	_	_	_	_	_
34	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
38	control	_	NOUN	_	Number=Sing	_	_	_	_
39	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	up	_	ADV	_	_	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011804	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
6	development	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	function	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	development	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	function	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	tightly	_	ADV	_	_	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	signal	_	ADJ	_	Number=Sing	_	_	_	_
13	transduction	_	NOUN	_	Number=Sing	_	_	_	_
14	pathways	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	surface	_	NOUN	_	Number=Sing	_	_	_	_
21	receptors	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
24	signaling	_	NOUN	_	Number=Sing	_	_	_	_
25	molecules	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factors	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	ADP	_	_	_	_	_	_
2	1988	_	NUM	_	NumType=Card	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	several	_	ADJ	_	Degree=Pos	_	_	_	_
5	families	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	functionally	_	ADV	_	_	_	_	_	_
8	important	_	ADJ	_	Degree=Pos	_	_	_	_
9	T	_	NOUN	_	NumType=Card	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
15	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	These	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
2	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	Ikaros	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	LKLF	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	GATA3	_	PROPN	_	Number=Sing	_	_	_	_
10	zinc	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	finger	_	NOUN	_	Number=Sing	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	;	_	PUNCT	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	Ets	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	CREB	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	ATF	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B/Rel	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factors	_	NOUN	_	Number=Plur	_	_	_	_
31	;	_	PUNCT	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	Stat	_	PROPN	_	Number=Sing	_	_	_	_
34	proteins	_	NOUN	_	Number=Plur	_	_	_	_
35	;	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	HMG	_	NOUN	_	Number=Sing	_	_	_	_
38	box	_	NOUN	_	Number=Sing	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	factors	_	NOUN	_	Number=Plur	_	_	_	_
41	such	_	ADJ	_	Degree=Pos	_	_	_	_
42	as	_	ADP	_	_	_	_	_	_
43	LEF1	_	PROPN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	TCF1	_	PROPN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	Sox4	_	PROPN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	review	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	summarize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
8	current	_	ADJ	_	Degree=Pos	_	_	_	_
9	understanding	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
13	regulation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	development	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	function	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	particular	_	ADJ	_	Degree=Pos	_	_	_	_
22	emphasis	_	NOUN	_	Number=Sing	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	results	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	recent	_	ADJ	_	Degree=Pos	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	targeting	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
32	experiments	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	SCONJ	_	_	_	_	_	_
4	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
6	understanding	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
10	pathways	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	development	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	function	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
20	results	_	NOUN	_	Number=Plur	_	_	_	_
21	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	novel	_	NOUN	_	Number=Sing	_	_	_	_
24	targets	_	NOUN	_	Number=Plur	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	pharmacological	_	ADJ	_	Degree=Pos	_	_	_	_
29	manipulation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	immunity	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011812	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	product	_	NOUN	_	Number=Sing	_	_	_	_
8	related	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	p50/p105	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	participates	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
19	through	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	Rel	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	related	_	ADJ	_	Degree=Pos	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	inducible	_	ADJ	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	early	_	ADJ	_	Degree=Pos	_	_	_	_
23	activation	_	NOUN	_	Degree=Pos	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
28	blood	_	NOUN	_	Number=Sing	_	_	_	_
29	T	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	open	_	ADJ	_	Degree=Pos	_	_	_	_
6	reading	_	NOUN	_	Number=Sing	_	_	_	_
7	frame	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	900	_	NUM	_	NumType=Card	_	_	_	_
10	amino	_	ADJ	_	Degree=Pos	_	_	_	_
11	acids	_	NOUN	_	Number=Plur	_	_	_	_
12	capable	_	ADJ	_	Degree=Pos	_	_	_	_
13	of	_	SCONJ	_	_	_	_	_	_
14	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	97	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kDa	_	NOUN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	most	_	ADV	_	_	_	_	_	_
5	similar	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	105	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kDa	_	NOUN	_	Number=Sing	_	_	_	_
11	precursor	_	NOUN	_	Number=Sing	_	_	_	_
12	polypeptide	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	p50-NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B.	_	PROPN	_	Number=Sing	_	_	_	_
18	Like	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	105	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kDa	_	NOUN	_	Number=Sing	_	_	_	_
23	precursor	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
26	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	amino	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	terminal	_	NOUN	_	Number=Sing	_	_	_	_

1	Rel	_	ADV	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	related	_	ADJ	_	Degree=Pos	_	_	_	_
4	domain	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	about	_	ADV	_	_	_	_	_	_
7	300	_	NUM	_	NumType=Card	_	_	_	_
8	amino	_	PROPN	_	Number=Sing	_	_	_	_
9	acids	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	carboxy	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	terminal	_	NOUN	_	Number=Sing	_	_	_	_
15	domain	_	NOUN	_	Number=Sing	_	_	_	_
16	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	six	_	NUM	_	NumType=Card	_	_	_	_
18	full	_	ADJ	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	cycle	_	NOUN	_	Number=Sing	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	ankyrin	_	NOUN	_	Number=Sing	_	_	_	_
23	repeats	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	downstream	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	Rel	_	PROPN	_	Number=Sing	_	_	_	_
12	domain	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	excluding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	repeats	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	sites	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	refer	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	p50B	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	analogy	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	p50-NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	full	_	ADJ	_	Degree=Pos	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	length	_	NOUN	_	Number=Sing	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	p97	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	p50B	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	able	_	ADJ	_	Degree=Pos	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	form	_	VERB	_	VerbForm=Inf	_	_	_	_
6	heteromeric	_	ADJ	_	Degree=Pos	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	complexes	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	RelB	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	as	_	ADV	_	_	_	_	_	_
16	well	_	ADV	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	p65	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	p50	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	two	_	NUM	_	NumType=Card	_	_	_	_
25	subunits	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B.	_	PROPN	_	Number=Sing	_	_	_	_
31	Transient	_	ADJ	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	transfection	_	NOUN	_	Number=Sing	_	_	_	_
34	experiments	_	NOUN	_	Number=Plur	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	embryonal	_	ADJ	_	Degree=Pos	_	_	_	_
37	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	functional	_	ADJ	_	Degree=Pos	_	_	_	_
42	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
43	between	_	ADP	_	_	_	_	_	_
44	p50B	_	NOUN	_	Number=Sing	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	RelB	_	NOUN	_	Number=Sing	_	_	_	_
47	or	_	CCONJ	_	_	_	_	_	_
48	p65	_	NUM	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
53	reporter	_	NOUN	_	Number=Sing	_	_	_	_
54	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
55	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
56	on	_	ADP	_	_	_	_	_	_
57	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
58	kappa	_	NOUN	_	Number=Sing	_	_	_	_
59	B	_	NOUN	_	Number=Sing	_	_	_	_
60	site	_	NOUN	_	Number=Sing	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	imply	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	existence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	complex	_	ADJ	_	Degree=Pos	_	_	_	_
9	family	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	like	_	ADP	_	Degree=Pos	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011814	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	MEK1	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	signal	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	kinases	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	TCR	_	NOUN	_	Number=Sing	_	_	_	_
2	engagement	_	NOUN	_	Number=Sing	_	_	_	_
3	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	Raf	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Active	_	ADJ	_	Degree=Pos	_	_	_	_
2	Raf	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	phosphorylates	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	MAP	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	kinase	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
19	signal	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	kinase	_	NOUN	_	Number=Sing	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	MEK1	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	turn	_	NOUN	_	Number=Sing	_	_	_	_
32	phosphorylates	_	NOUN	_	Number=Plur	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	MAP	_	NOUN	_	Number=Sing	_	_	_	_
37	kinases	_	NOUN	_	Number=Plur	_	_	_	_
38	/	_	PUNCT	_	_	_	_	_	_
39	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
40	signal	_	NOUN	_	Number=Sing	_	_	_	_
41	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	kinases	_	NOUN	_	Number=Plur	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	ERK1	_	PROPN	_	Number=Sing	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	ERK2	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Raf	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	sought	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
7	whether	_	SCONJ	_	_	_	_	_	_
8	MEK1	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	ERK	_	NOUN	_	Number=Sing	_	_	_	_
11	activities	_	NOUN	_	Number=Plur	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	stimulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	constitutively	_	ADV	_	_	_	_	_	_
4	active	_	ADJ	_	Degree=Pos	_	_	_	_
5	Raf	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	MEK1	_	PROPN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	calcium	_	NOUN	_	Number=Sing	_	_	_	_
29	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	PMA	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	together	_	ADV	_	_	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	calcium	_	NOUN	_	Number=Sing	_	_	_	_
38	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	expression	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	each	_	DET	_	_	_	_	_	_
43	protein	_	NOUN	_	Number=Sing	_	_	_	_
44	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
45	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
46	to	_	PART	_	_	_	_	_	_
47	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
48	NF	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	AT	_	ADP	_	_	_	_	_	_
51	activity	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	MEK1	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	interfering	_	VERB	_	VerbForm=Ger	_	_	_	_
6	mutants	_	NOUN	_	Number=Plur	_	_	_	_
7	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	ability	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	constitutively	_	ADV	_	_	_	_	_	_
24	active	_	ADJ	_	Degree=Pos	_	_	_	_
25	Ras	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	Raf	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	costimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	AT	_	ADP	_	_	_	_	_	_
35	activity	_	NOUN	_	Number=Sing	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	calcium	_	NOUN	_	Number=Sing	_	_	_	_
39	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	MAP	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	MKP	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	blocks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	ERK	_	PROPN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	AT	_	ADP	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	calcium	_	NOUN	_	Number=Sing	_	_	_	_
35	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	PMA	_	PROPN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	addition	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	MKP	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	neutralized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
49	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
50	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	by	_	ADP	_	_	_	_	_	_
52	active	_	ADJ	_	Degree=Pos	_	_	_	_
53	Raf	_	NOUN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	1	_	NUM	_	NumType=Card	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	MEK1	_	PROPN	_	Number=Sing	_	_	_	_
58	expression	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	MAP	_	NOUN	_	Number=Sing	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	signal	_	NOUN	_	Number=Sing	_	_	_	_
8	transduction	_	NOUN	_	Number=Sing	_	_	_	_
9	pathway	_	NOUN	_	Number=Sing	_	_	_	_
10	consisting	_	VERB	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Raf	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	MEK1	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	ERK1	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	ERK2	_	PROPN	_	Number=Sing	_	_	_	_
22	functions	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	T	_	NOUN	_	Number=Sing	_	_	_	_
34	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011815	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Function	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	immune	_	NOUN	_	Number=Sing	_	_	_	_
12	system	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Nevertheless	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
4	properties	_	NOUN	_	Number=Plur	_	_	_	_
5	seem	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	most	_	ADV	_	_	_	_	_	_
9	extensively	_	ADV	_	_	_	_	_	_
10	exploited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	immune	_	NOUN	_	Number=Sing	_	_	_	_
16	system	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Among	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	properties	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	PROPN	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	's	_	PART	_	_	_	_	_	_
10	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
11	posttranslational	_	ADJ	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	many	_	ADJ	_	Degree=Pos	_	_	_	_
17	pathogenic	_	ADJ	_	Degree=Pos	_	_	_	_
18	signals	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	direct	_	ADJ	_	Degree=Pos	_	_	_	_
22	participation	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	signaling	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	potency	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	great	_	ADJ	_	Degree=Pos	_	_	_	_
38	variety	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	genes	_	NOUN	_	Number=Plur	_	_	_	_
41	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
42	immunologically	_	ADV	_	_	_	_	_	_
43	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
44	proteins	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vertebrates	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	five	_	NUM	_	NumType=Card	_	_	_	_
5	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	subunits	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	currently	_	ADV	_	_	_	_	_	_
11	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	which	_	PRON	_	PronType=Int	_	_	_	_
13	might	_	AUX	_	VerbForm=Fin	_	_	_	_
14	extensively	_	ADV	_	_	_	_	_	_
15	heterodimerize	_	VERB	_	VerbForm=Inf	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	thereby	_	ADV	_	_	_	_	_	_
18	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
19	complexes	_	NOUN	_	Number=Plur	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	DNA	_	PROPN	_	Number=Sing	_	_	_	_
26	sequence	_	NOUN	_	Number=Sing	_	_	_	_
27	specificity	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	type	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	stage	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	specific	_	ADJ	_	Degree=Pos	_	_	_	_
38	distribution	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	binding	_	VERB	_	Number=Sing	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	dimers	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	tightly	_	ADV	_	_	_	_	_	_
13	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	accessory	_	ADJ	_	Degree=Pos	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
19	kappa	_	VERB	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	subunits	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	there	_	PRON	_	_	_	_	_	_
25	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	also	_	ADV	_	_	_	_	_	_
27	five	_	NUM	_	NumType=Card	_	_	_	_
28	different	_	ADJ	_	Degree=Pos	_	_	_	_
29	species	_	NOUN	_	Number=Plur	_	_	_	_
30	currently	_	ADV	_	_	_	_	_	_
31	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	vertebrates	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
2	kappa	_	VERB	_	Number=Sing	_	_	_	_
3	B	_	PROPN	_	Number=Sing	_	_	_	_
4	proteins	_	NOUN	_	Number=Plur	_	_	_	_
5	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	uptake	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	complexes	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	exception	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	3	_	NUM	_	NumType=Card	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	addition	_	NOUN	_	Number=Sing	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	function	_	VERB	_	VerbForm=Inf	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	subunit	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	th	_	DET	_	Number=Sing	_	_	_	_
21	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Other	_	ADJ	_	Degree=Pos	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	kappa	_	VERB	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	rather	_	ADV	_	_	_	_	_	_
8	involved	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	SCONJ	_	_	_	_	_	_
10	terminating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	PROPN	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	's	_	PART	_	_	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	events	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	kappa	_	VERB	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	i.e.	_	X	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	complex	_	ADJ	_	Degree=Pos	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	involve	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
6	reactions	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	seem	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	'	_	PART	_	_	_	_	_	_
16	redox	_	NOUN	_	Number=Sing	_	_	_	_
17	status	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Interference	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	beneficial	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	SCONJ	_	_	_	_	_	_
16	suppressing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	toxic	_	ADJ	_	Degree=Pos	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	septic	_	NOUN	_	Number=Sing	_	_	_	_
20	shock	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	graft	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	vs	_	NOUN	_	Abbr=Yes	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	host	_	NOUN	_	Number=Sing	_	_	_	_
27	reactions	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	acute	_	ADJ	_	Degree=Pos	_	_	_	_
30	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	reactions	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	acute	_	ADJ	_	Degree=Pos	_	_	_	_
34	phase	_	NOUN	_	Number=Sing	_	_	_	_
35	response	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	radiation	_	NOUN	_	Number=Sing	_	_	_	_
39	damage	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	protease	_	NOUN	_	Number=Sing	_	_	_	_
14	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	pharmacological	_	ADJ	_	Degree=Pos	_	_	_	_
19	basis	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	SCONJ	_	_	_	_	_	_
21	interfering	_	VERB	_	VerbForm=Ger	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
24	acute	_	NOUN	_	Degree=Pos	_	_	_	_
25	processes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011816	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
4	system	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	isolate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
9	negative	_	ADJ	_	Degree=Pos	_	_	_	_
10	effector	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	DNA	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	binding	_	VERB	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Oct	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	SYM	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	interactions	_	NOUN	_	Number=Plur	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factors	_	NOUN	_	Number=Plur	_	_	_	_
10	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	important	_	ADJ	_	Degree=Pos	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	eukaryotic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	isolate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
4	clones	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	dominantly	_	ADV	_	_	_	_	_	_
7	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	DNA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	Oct	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	chosen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	representative	_	ADJ	_	Degree=Pos	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
25	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	developed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	novel	_	NOUN	_	Number=Sing	_	_	_	_
29	screening	_	NOUN	_	Number=Sing	_	_	_	_
30	system	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	employs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	Escherichia	_	PROPN	_	Number=Sing	_	_	_	_
5	coli	_	NOUN	_	Number=Sing	_	_	_	_
6	tester	_	NOUN	_	Number=Sing	_	_	_	_
7	strain	_	NOUN	_	Number=Sing	_	_	_	_
8	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	lac	_	NOUN	_	Number=Sing	_	_	_	_
12	operon	_	NOUN	_	Number=Sing	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	reporter	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	lac	_	NOUN	_	Number=Sing	_	_	_	_
21	operator	_	NOUN	_	Number=Sing	_	_	_	_
22	sequence	_	NOUN	_	Number=Sing	_	_	_	_
23	replaced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	octamer	_	NOUN	_	Number=Sing	_	_	_	_
27	sequence	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Oct	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	tester	_	NOUN	_	Number=Sing	_	_	_	_
8	strain	_	NOUN	_	Number=Sing	_	_	_	_
9	represses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	reporter	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	changes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	Lac	_	PROPN	_	Number=Sing	_	_	_	_
25	+	_	SYM	_	_	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	Lac	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Introduction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	library	_	NOUN	_	Number=Sing	_	_	_	_
7	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
12	line	_	NOUN	_	Number=Sing	_	_	_	_
13	into	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	Oct	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	harboring	_	VERB	_	VerbForm=Ger	_	_	_	_
20	tester	_	NOUN	_	Number=Sing	_	_	_	_
21	strain	_	NOUN	_	Number=Sing	_	_	_	_
22	allowed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	selection	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	three	_	NUM	_	NumType=Card	_	_	_	_
26	Lac	_	NOUN	_	Number=Sing	_	_	_	_
27	+	_	SYM	_	_	_	_	_	_
28	clones	_	NOUN	_	Number=Plur	_	_	_	_
29	out	_	ADP	_	_	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	x	_	SYM	_	_	_	_	_	_
33	10	_	NUM	_	NumType=Card	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	5	_	NUM	_	NumType=Card	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	transformants	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	hT86	_	NOUN	_	NumType=Card	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	putative	_	ADJ	_	Degree=Pos	_	_	_	_
10	zinc	_	NOUN	_	Number=Sing	_	_	_	_
11	finger	_	NOUN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	derepress	_	VERB	_	VerbForm=Inf	_	_	_	_
17	beta	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	galactosidase	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	Oct	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	harboring	_	VERB	_	VerbForm=Ger	_	_	_	_
28	tester	_	NOUN	_	Number=Sing	_	_	_	_
29	strain	_	NOUN	_	Number=Sing	_	_	_	_
30	at	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
33	level	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	gel	_	NOUN	_	Number=Sing	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	hT86	_	NOUN	_	NumType=Card	_	_	_	_
8	attenuated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	intensity	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	retarded	_	ADJ	_	Degree=Pos	_	_	_	_
14	band	_	NOUN	_	Number=Sing	_	_	_	_
15	composed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	octamer	_	NOUN	_	Number=Sing	_	_	_	_
19	probe	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	Oct	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
28	negative	_	ADJ	_	Degree=Pos	_	_	_	_
29	effect	_	NOUN	_	Number=Sing	_	_	_	_
30	on	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	DNA	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	binding	_	VERB	_	Number=Sing	_	_	_	_
35	activity	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	Oct	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	SYM	_	_	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	strategy	_	NOUN	_	Number=Sing	_	_	_	_
3	described	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	here	_	ADV	_	PronType=Dem	_	_	_	_
5	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	new	_	ADJ	_	Degree=Pos	_	_	_	_
8	approach	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	SCONJ	_	_	_	_	_	_
10	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	interactions	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	govern	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	complex	_	ADJ	_	Degree=Pos	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011827	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tpl	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
11	lines	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	triggering	_	VERB	_	VerbForm=Ger	_	_	_	_
14	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
15	signaling	_	NOUN	_	Number=Sing	_	_	_	_
16	pathways	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	ADV	_	PronType=Rel	_	_	_	_
18	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Tpl	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
25	lines	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	Tpl	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
21	signaling	_	VERB	_	Number=Sing	_	_	_	_
22	molecules	_	NOUN	_	Number=Plur	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
37	/	_	PUNCT	_	_	_	_	_	_
38	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
39	pathways	_	NOUN	_	Number=Plur	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	promoted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	combinations	_	NOUN	_	Number=Plur	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
47	molecules	_	NOUN	_	Number=Plur	_	_	_	_
48	that	_	PRON	_	PronType=Rel	_	_	_	_
49	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
50	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
51	pathways	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	therefore	_	ADV	_	_	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	signals	_	NOUN	_	Number=Plur	_	_	_	_
8	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	convergence	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	MAPK	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
20	pathway	_	NOUN	_	Number=Sing	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	Tpl	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	depend	_	VERB	_	VerbForm=Inf	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	signals	_	NOUN	_	Number=Plur	_	_	_	_
23	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	Raf1	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	only	_	ADV	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	Tpl	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	fully	_	ADV	_	_	_	_	_	_
19	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
23	negative	_	ADJ	_	Degree=Pos	_	_	_	_
24	mutant	_	NOUN	_	Number=Sing	_	_	_	_
25	MEK1S218/222A	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	MEK1	_	PROPN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	MEK2	_	PROPN	_	Number=Sing	_	_	_	_
31	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
32	PD098059	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	findings	_	NOUN	_	Number=Plur	_	_	_	_
12	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	Tpl	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	either	_	CCONJ	_	_	_	_	_	_
24	independent	_	ADJ	_	Degree=Pos	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	only	_	ADV	_	_	_	_	_	_
27	partially	_	ADV	_	_	_	_	_	_
28	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	MEK1	_	PROPN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	MEK2	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
5	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	under	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	control	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	not	_	ADV	_	_	_	_	_	_
21	only	_	ADV	_	_	_	_	_	_
22	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	also	_	ADV	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	MEK	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Experiments	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	COS	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	EL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	4	_	NUM	_	NumType=Card	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	confirmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	hypotheses	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	Tpl	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	Tpl	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	fully	_	ADV	_	_	_	_	_	_
23	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
27	negative	_	ADJ	_	Degree=Pos	_	_	_	_
28	mutant	_	NOUN	_	Number=Sing	_	_	_	_
29	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
30	delta418	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
33	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
34	only	_	ADV	_	_	_	_	_	_
35	partially	_	ADV	_	_	_	_	_	_
36	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
40	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
41	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	Tpl	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2-	_	PUNCT	_	_	_	_	_	_
8	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
9	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	under	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	control	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	combination	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	independent	_	ADJ	_	Degree=Pos	_	_	_	_
24	pathways	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	pathways	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	fully	_	ADV	_	_	_	_	_	_
5	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	or	_	CCONJ	_	_	_	_	_	_
11	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	X	_	PROPN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	L	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011829	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	GCS	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	profoundly	_	ADV	_	_	_	_	_	_
6	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
7	several	_	ADJ	_	Degree=Pos	_	_	_	_
8	aspects	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	immunity	_	NOUN	_	Number=Sing	_	_	_	_
13	largely	_	ADV	_	_	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	at	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
24	levels	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	GCS	_	NOUN	_	Number=Plur	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	act	_	VERB	_	VerbForm=Inf	_	_	_	_
7	indirectly	_	ADV	_	_	_	_	_	_
8	by	_	SCONJ	_	_	_	_	_	_
9	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
11	growth	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	turn	_	NOUN	_	Number=Sing	_	_	_	_
20	blocks	_	NOUN	_	Number=Plur	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	immunity	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	SCONJ	_	_	_	_	_	_
2	exerting	_	VERB	_	VerbForm=Ger	_	_	_	_
3	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
4	antiproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	GCS	_	PROPN	_	Number=Sing	_	_	_	_
8	diffuse	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	into	_	ADP	_	_	_	_	_	_
10	target	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	where	_	ADV	_	PronType=Rel	_	_	_	_
13	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
14	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	turn	_	NOUN	_	Number=Sing	_	_	_	_
22	translocates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
26	where	_	ADV	_	PronType=Rel	_	_	_	_
27	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
28	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	through	_	ADP	_	_	_	_	_	_
34	direct	_	ADJ	_	Degree=Pos	_	_	_	_
35	binding	_	NOUN	_	Number=Sing	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
39	response	_	NOUN	_	Number=Sing	_	_	_	_
40	elements	_	NOUN	_	Number=Plur	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	GRE	_	PROPN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	which	_	PRON	_	PronType=Rel	_	_	_	_
46	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
47	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	promoter	_	ADJ	_	Degree=Pos	_	_	_	_
51	region	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
54	genes	_	NOUN	_	Number=Plur	_	_	_	_
55	or	_	CCONJ	_	_	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	alternatively	_	ADV	_	_	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	through	_	ADP	_	_	_	_	_	_
60	antagonism	_	NOUN	_	Number=Sing	_	_	_	_
61	of	_	ADP	_	_	_	_	_	_
62	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
63	action	_	NOUN	_	Number=Sing	_	_	_	_
64	of	_	ADP	_	_	_	_	_	_
65	transcription	_	NOUN	_	Number=Sing	_	_	_	_
66	factors	_	NOUN	_	Number=Plur	_	_	_	_
67	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
68	for	_	ADP	_	_	_	_	_	_
69	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
70	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
71	activation	_	NOUN	_	Number=Sing	_	_	_	_
72	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
5	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	GCS	_	PROPN	_	Number=Sing	_	_	_	_
12	up	_	ADP	_	_	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	regulate	_	VERB	_	Degree=Pos	_	_	_	_
15	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
23	effects	_	NOUN	_	Number=Plur	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	target	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	review	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	summarize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	current	_	ADJ	_	Degree=Pos	_	_	_	_
9	state	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	knowledge	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	action	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	GCS	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	including	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	steroid	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	rebound	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	ensues	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	upon	_	ADP	_	_	_	_	_	_
32	GCS	_	NOUN	_	Number=Sing	_	_	_	_
33	withdrawal	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011833	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Selenium	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	PROPN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	HIV	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	LTR	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	eukaryotic	_	ADJ	_	Degree=Pos	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	PROPN	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	involved	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	various	_	ADJ	_	Degree=Pos	_	_	_	_
17	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	as	_	ADV	_	_	_	_	_	_
20	well	_	ADV	_	Degree=Pos	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	HIV	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	replication	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	prooxidants	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	several	_	ADJ	_	Degree=Pos	_	_	_	_
13	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
14	eliciting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
16	stress	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	such	_	ADJ	_	Degree=Pos	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	UV	_	PROPN	_	Number=Sing	_	_	_	_
25	irradiation	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	other	_	ADJ	_	Degree=Pos	_	_	_	_
28	mediators	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Various	_	ADJ	_	Degree=Pos	_	_	_	_
2	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
3	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	effects	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	selenium	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	integral	_	ADJ	_	Degree=Pos	_	_	_	_
15	component	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
18	peroxidase	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	GPX	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	selenium	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	deprived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	ESb	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	L	_	X	_	Number=Sing	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	supplementation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	selenium	_	NOUN	_	Number=Sing	_	_	_	_
16	led	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
20	increase	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	GPX	_	NOUN	_	Number=Sing	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	TNF	_	PROPN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	significantly	_	ADV	_	_	_	_	_	_
18	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	under	_	ADP	_	_	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	conditions	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Likewise	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	reporter	_	NOUN	_	Number=Sing	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	using	_	VERB	_	VerbForm=Ger	_	_	_	_
7	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
8	constructs	_	NOUN	_	Number=Plur	_	_	_	_
9	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	HIV	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	long	_	ADJ	_	Degree=Pos	_	_	_	_
16	terminal	_	NOUN	_	Number=Sing	_	_	_	_
17	repeat	_	NOUN	_	Number=Sing	_	_	_	_
18	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	dose	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	selenium	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	selenium	_	NOUN	_	Number=Sing	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	PROPN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	since	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	selenium	_	ADJ	_	Number=Sing	_	_	_	_
6	supplementation	_	NOUN	_	Number=Sing	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Degree=Pos	_	_	_	_
19	target	_	NOUN	_	Number=Sing	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_
26	Document	_	NOUN	_	Number=Sing	_	_	_	_
27	0030011840	_	NUM	_	NumType=Card	_	_	_	_
28	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Soluble	_	ADJ	_	Degree=Pos	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	T-lymphocytes	_	PROPN	_	Number=Plur	_	_	_	_
7	modulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
13	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
14	TGF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	beta	_	NOUN	_	Number=Sing	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	glial	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Coordination	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	immune	_	ADJ	_	Degree=Pos	_	_	_	_
5	response	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	injury	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	disease	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	brain	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	postulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
17	bi-directional	_	ADJ	_	Degree=Pos	_	_	_	_
18	discourse	_	NOUN	_	Number=Sing	_	_	_	_
19	between	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	immune	_	NOUN	_	Number=Sing	_	_	_	_
22	system	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	central	_	ADJ	_	Degree=Pos	_	_	_	_
26	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
27	system	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	cross	_	NOUN	_	Number=Sing	_	_	_	_
3	communication	_	NOUN	_	Number=Sing	_	_	_	_
4	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
6	mediators	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	including	_	VERB	_	VerbForm=Ger	_	_	_	_
9	various	_	ADJ	_	Degree=Pos	_	_	_	_
10	growth	_	NOUN	_	Number=Sing	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	neuropeptides	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	supernatant	_	NOUN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	T-lymphocytes	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	able	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	potent	_	NOUN	_	Degree=Pos	_	_	_	_
22	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	TGF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	beta	_	NOUN	_	Number=Sing	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	glial	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
3	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
4	invokes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
6	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
7	distinct	_	VERB	_	Degree=Pos	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	kinase	_	NOUN	_	Number=Sing	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	protease	_	NOUN	_	Number=Sing	_	_	_	_
13	pathways	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TGF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	loss	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	80	_	NUM	_	NumType=Card	_	_	_	_
18	kDA	_	NOUN	_	Number=Sing	_	_	_	_
19	glial	_	ADJ	_	Degree=Pos	_	_	_	_
20	labile	_	NOUN	_	Number=Sing	_	_	_	_
21	repressor	_	NOUN	_	Number=Sing	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	GLRP	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
29	region	_	NOUN	_	Number=Sing	_	_	_	_
30	within	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	TFG	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	beta	_	NOUN	_	Number=Sing	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	GLRP	_	PROPN	_	Number=Sing	_	_	_	_
3	shares	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	some	_	DET	_	_	_	_	_	_
5	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	AP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	family	_	NOUN	_	Number=Sing	_	_	_	_
26	members	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	along	_	ADP	_	_	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	previous	_	ADJ	_	Degree=Pos	_	_	_	_
6	observations	_	NOUN	_	Number=Plur	_	_	_	_
7	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	potent	_	ADJ	_	Number=Sing	_	_	_	_
10	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	TGF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	beta	_	NOUN	_	Number=Sing	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	support	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	model	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	feedback	_	NOUN	_	Number=Sing	_	_	_	_
24	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
25	between	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	T-lymphocytes	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	astrocytes	_	NOUN	_	Number=Plur	_	_	_	_
31	via	_	ADP	_	_	_	_	_	_
32	TGF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	beta	_	NOUN	_	Number=Sing	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	immune	_	ADJ	_	Degree=Pos	_	_	_	_
40	response	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011843	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Distinct	_	ADJ	_	Degree=Pos	_	_	_	_
2	DNase	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	TAL	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lines	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	tal	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	frequently	_	ADV	_	_	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
12	acute	_	ADJ	_	Degree=Pos	_	_	_	_
13	lymphoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
14	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	ALL	_	DET	_	_	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	mast	_	ADJ	_	Degree=Pos	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	lineages	_	NOUN	_	Number=Plur	_	_	_	_
33	during	_	ADP	_	_	_	_	_	_
34	normal	_	ADJ	_	Degree=Pos	_	_	_	_
35	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	gain	_	VERB	_	VerbForm=Inf	_	_	_	_
3	further	_	ADJ	_	Degree=Pos	_	_	_	_
4	insight	_	NOUN	_	Number=Sing	_	_	_	_
5	into	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
8	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	tal	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	tal	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	chromatin	_	NOUN	_	Degree=Pos	_	_	_	_
22	structure	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	lines	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
32	lines	_	NOUN	_	Number=Plur	_	_	_	_
33	either	_	ADV	_	_	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	without	_	ADP	_	_	_	_	_	_
37	tal	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Tal	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	monoallelic	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
15	line	_	NOUN	_	Number=Sing	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	expresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	tal	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	absence	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
26	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
27	alteration	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	locus	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Methylation	_	PROPN	_	Number=Sing	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	tal	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	15	_	NUM	_	NumType=Card	_	_	_	_
9	'	_	PUNCT	_	_	_	_	_	_
10	GC	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	rich	_	ADJ	_	Degree=Pos	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	behaves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	like	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	CpG	_	PROPN	_	Number=Sing	_	_	_	_
18	island	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	hypomethylated	_	VERB	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	normal	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	methylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	de	_	PROPN	_	Number=Sing	_	_	_	_
28	novo	_	NOUN	_	Number=Sing	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	transcriptionally	_	ADV	_	_	_	_	_	_
31	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
32	alleles	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	lines	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Five	_	NUM	_	NumType=Card	_	_	_	_
2	major	_	ADJ	_	Degree=Pos	_	_	_	_
3	DNase	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HS	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	mapped	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	tal	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	locus	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	HS	_	INTJ	_	Number=Sing	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	IV	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	V	_	PROPN	_	Number=Sing	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	exclusively	_	ADV	_	_	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	lines	_	NOUN	_	Number=Plur	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	tal	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	promoters	_	NOUN	_	Number=Plur	_	_	_	_
26	1a	_	PROPN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	1b	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	HS	_	PROPN	_	Number=Sing	_	_	_	_
2	II	_	PROPN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	weak	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	absent	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	Hela	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	greatly	_	ADV	_	_	_	_	_	_
16	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
23	region	_	NOUN	_	Number=Sing	_	_	_	_
24	might	_	AUX	_	VerbForm=Fin	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	cis-activation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	tal	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	1b	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	line	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	HS	_	PROPN	_	Number=Sing	_	_	_	_
2	III	_	PROPN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	weak	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	HEL	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	greatly	_	ADV	_	_	_	_	_	_
12	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	DU528	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
18	line	_	NOUN	_	Number=Sing	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	bears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	t	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	1;14	_	NUM	_	NumType=Card	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	initiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	tal	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	within	_	ADP	_	_	_	_	_	_
33	exon	_	PROPN	_	Number=Sing	_	_	_	_
34	4	_	NUM	_	NumType=Card	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	elements	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	use	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	different	_	ADJ	_	Degree=Pos	_	_	_	_
16	tal	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	promoters	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011846	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	tax	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
7	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	c-sis	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	platelet	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	growth	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	-B	_	NOUN	_	_	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	through	_	ADP	_	_	_	_	_	_
26	interactions	_	NOUN	_	Number=Plur	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	zinc	_	NOUN	_	Number=Sing	_	_	_	_
30	finger	_	NOUN	_	Number=Sing	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	factors	_	NOUN	_	Number=Plur	_	_	_	_
33	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	NGFI	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	A/Egr	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	up	_	ADP	_	_	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	c-sis	_	NOUN	_	Number=Plur	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	platelet	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	B	_	NOUN	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	proto	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	Tax	_	NOUN	_	Number=Sing	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
31	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
32	virus	_	NOUN	_	Number=Sing	_	_	_	_
33	type	_	NOUN	_	Number=Sing	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
37	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	as	_	ADP	_	_	_	_	_	_
39	one	_	NUM	_	NumType=Card	_	_	_	_
40	possible	_	ADJ	_	Degree=Pos	_	_	_	_
41	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
44	transformation	_	NOUN	_	Number=Sing	_	_	_	_
45	by	_	ADP	_	_	_	_	_	_
46	human	_	ADJ	_	Degree=Pos	_	_	_	_
47	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
48	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
49	virus	_	NOUN	_	Number=Sing	_	_	_	_
50	type	_	NOUN	_	Number=Sing	_	_	_	_
51	1	_	NUM	_	NumType=Card	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	previous	_	ADJ	_	Degree=Pos	_	_	_	_
3	work	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	essential	_	ADJ	_	Degree=Pos	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	c-sis	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	Tax	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
22	element	_	NOUN	_	Number=Sing	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	TRE1	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	Tax	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	Sp3	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	NGFI	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	A	_	PROPN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	Egr	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	primary	_	ADJ	_	Degree=Pos	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	TRE1	_	PROPN	_	Number=Sing	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	Tax	_	NOUN	_	Number=Sing	_	_	_	_
28	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	work	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	s	_	X	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	whereby	_	ADV	_	_	_	_	_	_
15	Tax	_	NOUN	_	Number=Sing	_	_	_	_
16	transactivates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	c-sis	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	proto	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	Tax	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	able	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	significantly	_	ADV	_	_	_	_	_	_
12	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	template	_	NOUN	_	Number=Sing	_	_	_	_
19	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	257	_	NUM	_	NumType=Card	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	+	_	SYM	_	_	_	_	_	_
25	74	_	NUM	_	NumType=Card	_	_	_	_
26	region	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	c-sis	_	NOUN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	PROPN	_	Number=Sing	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	Tax	_	NOUN	_	Number=Sing	_	_	_	_
9	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	NGFI	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	A	_	PROPN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	Egr	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	using	_	VERB	_	VerbForm=Ger	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	TRE1	_	NOUN	_	Number=Sing	_	_	_	_
28	probe	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Tax	_	NOUN	_	Number=Sing	_	_	_	_
4	mutants	_	NOUN	_	Number=Plur	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	mutants	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	IEXC29S	_	PROPN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	IEXL320G	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	unable	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	significantly	_	ADV	_	_	_	_	_	_
18	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	c-sis	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	PDGF	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	co-immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	Tax	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	able	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	stably	_	ADV	_	_	_	_	_	_
12	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	NGFI	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	A/Egr	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	co-immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	Tax	_	NOUN	_	Number=Sing	_	_	_	_
9	mutant	_	NOUN	_	Number=Sing	_	_	_	_
10	IEXC29S	_	PROPN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	unable	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	NGFI-A	_	PROPN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	Egr	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	whereas	_	SCONJ	_	_	_	_	_	_
23	Tax	_	NOUN	_	Number=Sing	_	_	_	_
24	mutant	_	NOUN	_	Number=Sing	_	_	_	_
25	IEXL320G	_	PROPN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	able	_	ADJ	_	Degree=Pos	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	NGFI	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	A/Egr	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011848	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	IRF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	pathway	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	DNA	_	NOUN	_	Number=Sing	_	_	_	_
10	damage	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	particularly	_	ADV	_	_	_	_	_	_
4	susceptible	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	DNA	_	NOUN	_	Number=Sing	_	_	_	_
7	damage	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	form	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	'	_	PUNCT	_	_	_	_	_	_
22	altruistic	_	ADJ	_	Degree=Pos	_	_	_	_
23	suicide	_	NOUN	_	Number=Sing	_	_	_	_
24	'	_	PUNCT	_	_	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	counter	_	VERB	_	VerbForm=Inf	_	_	_	_
27	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	intrinsic	_	ADJ	_	Degree=Pos	_	_	_	_
29	high	_	ADJ	_	Degree=Pos	_	_	_	_
30	potential	_	NOUN	_	Number=Sing	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	mutation	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
35	expansion	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	tumour	_	NOUN	_	Number=Sing	_	_	_	_
3	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
4	p53	_	NOUN	_	Number=Sing	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	type	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	yet	_	ADV	_	_	_	_	_	_
21	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	p53	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	independent	_	ADJ	_	Degree=Pos	_	_	_	_
26	pathway	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	s	_	X	_	_	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	same	_	ADJ	_	Degree=Pos	_	_	_	_
35	event	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	mitogen	_	ADJ	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	mature	_	ADJ	_	Degree=Pos	_	_	_	_
41	T	_	NOUN	_	Number=Sing	_	_	_	_
42	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	DNA	_	NOUN	_	Number=Sing	_	_	_	_
5	damage	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	antioncogenic	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	interferon	_	NOUN	_	Number=Sing	_	_	_	_
21	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	IRF	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	different	_	ADJ	_	Degree=Pos	_	_	_	_
4	anti-onco	_	X	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	genic	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	p53	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	IRF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
20	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
21	pathways	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	T	_	PROPN	_	Number=Sing	_	_	_	_
24	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	beta	_	NOUN	_	Number=Sing	_	_	_	_
13	converting	_	VERB	_	VerbForm=Ger	_	_	_	_
14	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	ICE	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
22	homologue	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	Caenorhabditis	_	PROPN	_	Number=Sing	_	_	_	_
26	elegans	_	NOUN	_	Number=Plur	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	death	_	NOUN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	ced-3	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	IRF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
2	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IRF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	results	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	ICE	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	radiation	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011851	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Effects	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CD45	_	PROPN	_	Number=Sing	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	PROPN	_	Number=Sing	_	_	_	_
8	B.	_	PROPN	_	Number=Sing	_	_	_	_
9	Implications	_	NOUN	_	Number=Plur	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	replication	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	replication	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	through	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	TCR	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	anti-CD45	_	ADJ	_	Number=Sing	_	_	_	_
4	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
5	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	infected	_	VERB	_	Degree=Pos	_	_	_	_
12	individuals	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	interrelationships	_	NOUN	_	Number=Plur	_	_	_	_
8	between	_	ADP	_	_	_	_	_	_
9	CD45	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	HIV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	further	_	ADV	_	_	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	measured	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	LTR	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	lines	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
19	against	_	ADP	_	_	_	_	_	_
20	CD45	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	lacked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	CD45	_	NOUN	_	Number=Sing	_	_	_	_
30	on	_	ADP	_	_	_	_	_	_
31	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
32	surfaces	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	First	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	anti-CD45	_	PROPN	_	Number=Sing	_	_	_	_
4	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
5	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
8	basal	_	ADJ	_	Degree=Pos	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	LTR	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Second	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	lack	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	CD45	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	signal	_	VERB	_	VerbForm=Inf	_	_	_	_
13	via	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	TCR	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	supported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
19	levels	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	viral	_	ADJ	_	Degree=Pos	_	_	_	_
22	replication	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	due	_	ADP	_	_	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	presence	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	active	_	ADJ	_	Degree=Pos	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	complexes	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	CD45	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	displayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	CD45	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	surfaces	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CD45	_	PROPN	_	Number=Sing	_	_	_	_
4	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	active	_	ADJ	_	Degree=Pos	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	physiology	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	replication	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_
23	Document	_	NOUN	_	Number=Sing	_	_	_	_
24	0030011855	_	NUM	_	NumType=Card	_	_	_	_
25	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Astrocytes	_	NOUN	_	Number=Plur	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	glioblastoma	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	express	_	VERB	_	Degree=Pos	_	_	_	_
6	novel	_	NOUN	_	Number=Sing	_	_	_	_
7	octamer	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	DNA	_	PROPN	_	Number=Sing	_	_	_	_
10	binding	_	VERB	_	Number=Sing	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	distinct	_	VERB	_	Number=Sing	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
16	Oct	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	Oct	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	proteins	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	'	_	PUNCT	_	_	_	_	_	_
3	octamer	_	NOUN	_	Number=Sing	_	_	_	_
4	'	_	PUNCT	_	_	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	ATGCAAAT	_	PROPN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	complement	_	NOUN	_	Number=Sing	_	_	_	_
11	ATTTGCAT	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	key	_	ADJ	_	Degree=Pos	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	regulation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	as	_	ADV	_	_	_	_	_	_
29	well	_	ADV	_	Degree=Pos	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	number	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	housekeeping	_	NOUN	_	Number=Sing	_	_	_	_
35	genes	_	NOUN	_	Number=Plur	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	all	_	DET	_	_	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	types	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	octamer	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	Oct	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2A	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	variants	_	NOUN	_	Number=Plur	_	_	_	_
14	thereof	_	NOUN	_	_	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	while	_	SCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	Oct	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	control	_	VERB	_	VerbForm=Inf	_	_	_	_
38	general	_	ADJ	_	Degree=Pos	_	_	_	_
39	octamer	_	NOUN	_	Number=Sing	_	_	_	_
40	site	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
43	transcription	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Various	_	ADJ	_	Degree=Pos	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	genes	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	example	_	NOUN	_	Number=Sing	_	_	_	_
7	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	MHC	_	PROPN	_	Number=Sing	_	_	_	_
12	class	_	NOUN	_	Number=Sing	_	_	_	_
13	II	_	NUM	_	Number=Sing	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	octamer	_	NOUN	_	Number=Sing	_	_	_	_
19	sequence	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	both	_	CCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	immune	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
34	systems	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	prompted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	us	_	PRON	_	Case=Acc|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	octamer	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	latter	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
4	mobility	_	NOUN	_	Number=Sing	_	_	_	_
5	shift	_	NOUN	_	Number=Sing	_	_	_	_
6	assay	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	at	_	ADV	_	_	_	_	_	_
9	least	_	ADV	_	Degree=Sup	_	_	_	_
10	six	_	NUM	_	NumType=Card	_	_	_	_
11	novel	_	NOUN	_	Number=Sing	_	_	_	_
12	octamer	_	NOUN	_	Number=Sing	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	extracts	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	cultured	_	VERB	_	Degree=Pos	_	_	_	_
22	mouse	_	NOUN	_	Number=Sing	_	_	_	_
23	astrocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	proteins	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	differentially	_	ADV	_	_	_	_	_	_
5	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	glioblastoma	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	neuroblastoma	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	lines	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
3	system	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	N	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Oct	_	X	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	bound	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	octamer	_	NOUN	_	Number=Sing	_	_	_	_
16	DNA	_	PROPN	_	Number=Sing	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	manner	_	NOUN	_	Number=Sing	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	indistinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	Oct	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	Oct	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2A	_	PROPN	_	Number=Sing	_	_	_	_
33	proteins	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	relationship	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	N	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Oct	_	PROPN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	Oct	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	Oct	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2A	_	PROPN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	clipping	_	NOUN	_	Number=Sing	_	_	_	_
22	bandshift	_	NOUN	_	Number=Sing	_	_	_	_
23	assays	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	reactivity	_	NOUN	_	Number=Sing	_	_	_	_
28	towards	_	ADP	_	_	_	_	_	_
29	antisera	_	NOUN	_	Number=Sing	_	_	_	_
30	raised	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	against	_	ADP	_	_	_	_	_	_
32	recombinant	_	ADJ	_	Number=Sing	_	_	_	_
33	Oct	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	Oct	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2A	_	NUM	_	Number=Sing	_	_	_	_
40	proteins	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	basis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	assays	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	all	_	DET	_	_	_	_	_	_
9	N	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	Oct	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
22	Oct	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	specific	_	ADJ	_	Degree=Pos	_	_	_	_
30	Oct	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2A	_	PROPN	_	Number=Sing	_	_	_	_
33	proteins	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	melanoma	_	NOUN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	N	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Oct	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	transfected	_	VERB	_	Degree=Pos	_	_	_	_
16	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	neither	_	CCONJ	_	_	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	nor	_	CCONJ	_	_	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
26	repressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	upon	_	ADP	_	_	_	_	_	_
28	contransfection	_	NOUN	_	Number=Sing	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	Oct	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2A	_	PROPN	_	Number=Sing	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	vector	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	speculate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	N	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Oct	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	other	_	ADJ	_	Degree=Pos	_	_	_	_
12	N	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	Oct	_	PROPN	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	role	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
28	system	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011857	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CD40	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	functional	_	ADJ	_	Degree=Pos	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	antigen	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	B7	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	independent	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	molecule	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	normal	_	ADJ	_	Degree=Pos	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	lung	_	NOUN	_	Number=Sing	_	_	_	_
19	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	CD40	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	important	_	ADJ	_	Degree=Pos	_	_	_	_
5	signaling	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_

1	Ag	_	NOUN	_	Number=Sing	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	certain	_	ADJ	_	Degree=Pos	_	_	_	_
5	bone	_	NOUN	_	Number=Sing	_	_	_	_
6	marrow	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CD40	_	PROPN	_	Number=Sing	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	mesenchymal	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	including	_	VERB	_	VerbForm=Ger	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Little	_	ADV	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	about	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	CD40	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	current	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	investigates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	_	_	_	_	_
8	CD40	_	PROPN	_	Number=Sing	_	_	_	_
9	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	lung	_	ADJ	_	Number=Sing	_	_	_	_
12	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	structure	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	interaction	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	hemopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Communication	_	NOUN	_	Number=Sing	_	_	_	_
2	between	_	ADP	_	_	_	_	_	_
3	resident	_	NOUN	_	Number=Sing	_	_	_	_
4	tissue	_	NOUN	_	Number=Sing	_	_	_	_
5	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	normal	_	ADJ	_	Degree=Pos	_	_	_	_
13	wound	_	NOUN	_	Number=Sing	_	_	_	_
14	healing	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	can	_	AUX	_	VerbForm=Fin	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	pathologic	_	ADJ	_	Degree=Pos	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	tissue	_	NOUN	_	Number=Sing	_	_	_	_
24	fibrosis	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
2	through	_	ADP	_	_	_	_	_	_
3	CD40	_	PROPN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	soluble	_	ADJ	_	Number=Sing	_	_	_	_
6	CD40	_	PROPN	_	Number=Sing	_	_	_	_
7	ligand	_	NOUN	_	Number=Sing	_	_	_	_
8	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	fibroblast	_	NOUN	_	Degree=Pos	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	as	_	SCONJ	_	_	_	_	_	_
13	evidenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	induction	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	proinflammatory	_	ADJ	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	chemoattractant	_	ADJ	_	Number=Sing	_	_	_	_
29	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	6	_	NUM	_	NumType=Card	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	8	_	NUM	_	NumType=Card	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	IFN	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	gamma-primed	_	ADJ	_	Degree=Pos	_	_	_	_
4	lung	_	ADJ	_	Number=Sing	_	_	_	_
5	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
6	costimulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
9	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
10	utilizing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	CD40	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	well	_	ADV	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
20	molecules	_	NOUN	_	Number=Plur	_	_	_	_
21	B7-1	_	PROPN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	B7	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Data	_	NOUN	_	Number=Sing	_	_	_	_
2	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	herein	_	ADV	_	_	_	_	_	_
4	support	_	VERB	_	Number=Sing	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	cognate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	interactions	_	NOUN	_	Number=Plur	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	tissue	_	NOUN	_	Number=Sing	_	_	_	_
12	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	infiltrating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	via	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	CD40	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	CD40L	_	NOUN	_	Number=Sing	_	_	_	_
23	pathway	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	augment	_	NOUN	_	Number=Sing	_	_	_	_
26	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	may	_	AUX	_	VerbForm=Fin	_	_	_	_
29	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
30	fibrogenesis	_	NOUN	_	Number=Sing	_	_	_	_
31	by	_	SCONJ	_	_	_	_	_	_
32	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
33	both	_	DET	_	_	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	types	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011858	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	PRON	_	PronType=Rel	_	_	_	_
4	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	class	_	NOUN	_	Number=Sing	_	_	_	_
7	II	_	NUM	_	NumType=Card	_	_	_	_
8	major	_	ADJ	_	Degree=Pos	_	_	_	_
9	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
10	complex	_	NOUN	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	DPA	_	PROPN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	member	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	subfamily	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	zinc	_	NOUN	_	Number=Sing	_	_	_	_
21	finger	_	NOUN	_	Number=Sing	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	Drosophila	_	PROPN	_	Number=Sing	_	_	_	_
27	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
28	control	_	NOUN	_	Number=Sing	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	sequence	_	NOUN	_	Number=Sing	_	_	_	_
5	element	_	NOUN	_	Number=Sing	_	_	_	_
6	termed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	J	_	NOUN	_	Number=Sing	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	regulated	_	VERB	_	Degree=Pos	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	class	_	NOUN	_	Number=Sing	_	_	_	_
17	II	_	NUM	_	NumType=Card	_	_	_	_
18	major	_	ADJ	_	Degree=Pos	_	_	_	_
19	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
20	complex	_	NOUN	_	Degree=Pos	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	recently	_	ADV	_	_	_	_	_	_
24	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	study	_	VERB	_	VerbForm=Inf	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	element	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	class	_	NOUN	_	Number=Sing	_	_	_	_
10	II	_	NUM	_	NumType=Card	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	further	_	ADV	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
17	library	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	screened	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	oligonucleotide	_	ADJ	_	Number=Sing	_	_	_	_
22	probes	_	NOUN	_	Number=Plur	_	_	_	_
23	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	both	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	S	_	NOUN	_	Number=Sing	_	_	_	_
27	element	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	nearby	_	ADJ	_	Degree=Pos	_	_	_	_
31	J	_	PROPN	_	Number=Sing	_	_	_	_
32	element	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	human	_	ADJ	_	Degree=Pos	_	_	_	_
36	DPA	_	NOUN	_	Number=Sing	_	_	_	_
37	gene	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	clones	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	procedure	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	one	_	NUM	_	NumType=Card	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Int	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	clone	_	NOUN	_	Number=Sing	_	_	_	_
15	18	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	here	_	ADV	_	PronType=Dem	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	predicted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
8	688	_	NUM	_	NumType=Card	_	_	_	_
9	amino	_	NOUN	_	Number=Sing	_	_	_	_
10	acid	_	NOUN	_	Number=Sing	_	_	_	_
11	residues	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	including	_	VERB	_	VerbForm=Ger	_	_	_	_
14	11	_	NUM	_	NumType=Card	_	_	_	_
15	zinc	_	NOUN	_	Number=Sing	_	_	_	_
16	finger	_	NOUN	_	Number=Sing	_	_	_	_
17	motifs	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	C2H2	_	NOUN	_	Number=Sing	_	_	_	_
21	type	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	C	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	terminal	_	NOUN	_	Number=Sing	_	_	_	_
27	region	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	Kruppel	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	like	_	ADP	_	_	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	conservation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	H/C	_	PROPN	_	Number=Sing	_	_	_	_
40	link	_	NOUN	_	Number=Sing	_	_	_	_
41	sequence	_	NOUN	_	Number=Sing	_	_	_	_
42	connecting	_	VERB	_	VerbForm=Ger	_	_	_	_
43	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	160	_	NUM	_	NumType=Card	_	_	_	_
3	N-	_	PUNCT	_	Number=Sing	_	_	_	_
4	terminal	_	NOUN	_	Number=Sing	_	_	_	_
5	amino	_	NOUN	_	Number=Sing	_	_	_	_
6	acids	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nonfinger	_	ADJ	_	Number=Sing	_	_	_	_
10	region	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	clone	_	NOUN	_	Number=Sing	_	_	_	_
13	18	_	NUM	_	NumType=Card	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	highly	_	ADV	_	_	_	_	_	_
16	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	similar	_	ADJ	_	Degree=Pos	_	_	_	_
19	regions	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	several	_	ADJ	_	Degree=Pos	_	_	_	_
22	other	_	ADJ	_	Degree=Pos	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	mouse	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	Drosophila	_	NOUN	_	Number=Sing	_	_	_	_
29	sequences	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	defining	_	VERB	_	VerbForm=Ger	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	subfamily	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	Kruppel	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	like	_	ADJ	_	_	_	_	_	_
38	zinc	_	NOUN	_	Number=Sing	_	_	_	_
39	finger	_	NOUN	_	Number=Sing	_	_	_	_
40	proteins	_	NOUN	_	Number=Plur	_	_	_	_
41	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	TAB	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	tramtrack	_	NOUN	_	Number=Sing	_	_	_	_
45	[	_	PUNCT	_	_	_	_	_	_
46	ttk	_	NOUN	_	Number=Sing	_	_	_	_
47	]	_	PUNCT	_	_	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	box	_	NOUN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	here	_	ADV	_	PronType=Dem	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	Drosophila	_	PROPN	_	Number=Sing	_	_	_	_
5	sequences	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	ttk	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
12	control	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	while	_	SCONJ	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	second	_	NOUN	_	Degree=Pos|NumType=Ord	_	_	_	_
18	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	zinc	_	NOUN	_	Number=Sing	_	_	_	_
23	finger	_	NOUN	_	Number=Sing	_	_	_	_
24	region	_	NOUN	_	Number=Sing	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	structure	_	NOUN	_	Number=Sing	_	_	_	_
29	important	_	ADJ	_	Degree=Pos	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	oocyte	_	NOUN	_	Number=Sing	_	_	_	_
32	development	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	acidic	_	ADJ	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	domain	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	N	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	terminal	_	NOUN	_	Number=Sing	_	_	_	_
12	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	clone	_	NOUN	_	Number=Sing	_	_	_	_
16	18	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	zinc	_	NOUN	_	Number=Sing	_	_	_	_
20	fingers	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	require	_	VERB	_	VerbForm=Inf	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	S	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	J	_	NOUN	_	Number=Sing	_	_	_	_
11	elements	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	separated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	10	_	NUM	_	NumType=Card	_	_	_	_
18	bp	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Antisense	_	ADJ	_	Degree=Pos	_	_	_	_
2	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	clone	_	VERB	_	VerbForm=Inf	_	_	_	_
5	18	_	NUM	_	NumType=Card	_	_	_	_
6	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	reporter	_	NOUN	_	Number=Sing	_	_	_	_
12	construct	_	NOUN	_	Number=Sing	_	_	_	_
13	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	DPA	_	PROPN	_	Number=Sing	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	functional	_	ADJ	_	Degree=Pos	_	_	_	_
21	importance	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
27	class	_	NOUN	_	Number=Sing	_	_	_	_
28	II	_	NUM	_	NumType=Card	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011859	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Alpha	_	PROPN	_	Number=Sing	_	_	_	_
2	4	_	NUM	_	NumType=Card	_	_	_	_
3	beta	_	NOUN	_	Number=Sing	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	CD49d	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	CD29	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	integrin	_	NOUN	_	Degree=Pos	_	_	_	_
11	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
21	induction	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	absence	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	altered	_	VERB	_	Degree=Pos	_	_	_	_
27	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	anti-CD3	_	ADJ	_	Number=Sing	_	_	_	_
30	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	integrin	_	PROPN	_	Number=Sing	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	4	_	NUM	_	NumType=Card	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	costimulus	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	secretion	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2R	_	NUM	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	purified	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
30	blood	_	NOUN	_	Number=Sing	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
13	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
17	molecule	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	when	_	ADV	_	PronType=Int	_	_	_	_
22	co-immobilized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
25	mAb	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	significantly	_	ADV	_	_	_	_	_	_
28	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	induction	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	factors	_	NOUN	_	Number=Plur	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	AT	_	ADP	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	AP	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	NF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kappa	_	PROPN	_	Number=Sing	_	_	_	_
46	B	_	PROPN	_	Number=Sing	_	_	_	_
47	as	_	SCONJ	_	_	_	_	_	_
48	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	by	_	ADP	_	_	_	_	_	_
50	electromobility	_	NOUN	_	Number=Sing	_	_	_	_
51	shift	_	NOUN	_	Number=Sing	_	_	_	_
52	assays	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	alpha	_	PROPN	_	Number=Sing	_	_	_	_
2	4	_	NUM	_	NumType=Card	_	_	_	_
3	beta	_	NOUN	_	Number=Sing	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	ligation	_	NOUN	_	Number=Sing	_	_	_	_
6	alone	_	ADV	_	_	_	_	_	_
7	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	no	_	DET	_	_	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	requirements	_	NOUN	_	Number=Plur	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	reflected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	requirements	_	NOUN	_	Number=Plur	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	secretion	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
16	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	including	_	VERB	_	VerbForm=Ger	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	TNF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	IFN	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	gamma	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
33	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	CSF	_	PROPN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	freshly	_	ADV	_	_	_	_	_	_
5	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vitro-cultured	_	VERB	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	require	_	VERB	_	VerbForm=Inf	_	_	_	_
16	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
19	secretion	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
24	alone	_	ADV	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Comparison	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	dose	_	NOUN	_	Number=Sing	_	_	_	_
5	response	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	anti-CD3	_	PROPN	_	Degree=Pos	_	_	_	_
8	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
9	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	half	_	ADJ	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	achieved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	using	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	same	_	ADJ	_	Degree=Pos	_	_	_	_
24	dose	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	anti-CD3	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	both	_	DET	_	_	_	_	_	_
29	freshly	_	ADV	_	_	_	_	_	_
30	isolated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	T	_	NOUN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	dose	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	OKT3	_	PROPN	_	Number=Sing	_	_	_	_
7	required	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	achieve	_	VERB	_	VerbForm=Inf	_	_	_	_
10	half	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	same	_	ADJ	_	Degree=Pos	_	_	_	_
17	using	_	VERB	_	VerbForm=Ger	_	_	_	_
18	PMA	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	different	_	ADJ	_	Degree=Pos	_	_	_	_
21	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	beta	_	NOUN	_	Number=Sing	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	ligands	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	alpha	_	DET	_	Number=Sing	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	ligands	_	NOUN	_	Number=Plur	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	due	_	ADP	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	stabilization	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	interaction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	substrate	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	rather	_	ADV	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	alpha	_	PROPN	_	Number=Sing	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	beta	_	NOUN	_	Number=Sing	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	freshly	_	ADV	_	_	_	_	_	_
13	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	delivers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
19	signal	_	NOUN	_	Number=Sing	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	synergizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	early	_	ADV	_	Degree=Pos	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	signals	_	NOUN	_	Number=Plur	_	_	_	_
25	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	TCR	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	CD3	_	PROPN	_	Number=Sing	_	_	_	_
30	ligation	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
33	DNA	_	PROPN	_	Number=Sing	_	_	_	_
34	binding	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	factors	_	NOUN	_	Number=Plur	_	_	_	_
39	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	for	_	ADP	_	_	_	_	_	_
41	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
42	gene	_	NOUN	_	Number=Sing	_	_	_	_
43	induction	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011865	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	beta-amyloid	_	ADJ	_	Number=Sing	_	_	_	_
10	peptides	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	interferon	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	gamma	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	murine	_	ADJ	_	Number=Sing	_	_	_	_
17	microglia	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	body	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	evidence	_	NOUN	_	Number=Sing	_	_	_	_
6	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	amyloid	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	beta	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	peptides	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	microglia	_	NOUN	_	Number=Sing	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	crucially	_	ADV	_	_	_	_	_	_
20	involved	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	Alzheimer	_	PROPN	_	Number=Sing	_	_	_	_
26	's	_	PART	_	_	_	_	_	_
27	disease	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	effort	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	further	_	ADV	_	_	_	_	_	_
6	elucidate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	biological	_	ADJ	_	Degree=Pos	_	_	_	_
9	effects	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	beta	_	NOUN	_	Number=Sing	_	_	_	_
13	towards	_	ADP	_	_	_	_	_	_
14	microglia	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	ability	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	beta	_	NOUN	_	Number=Sing	_	_	_	_
23	peptides	_	NOUN	_	Number=Plur	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	N9	_	PROPN	_	Number=Sing	_	_	_	_
37	murine	_	NOUN	_	Number=Sing	_	_	_	_
38	microglial	_	ADJ	_	Degree=Pos	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	line	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Co	_	X	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	microglia	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	suboptimal	_	ADJ	_	Degree=Pos	_	_	_	_
8	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	25	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	35	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	100	_	NUM	_	NumType=Card	_	_	_	_
19	U	_	PROPN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	ml	_	NOUN	_	Number=Sing	_	_	_	_
22	IFN	_	PROPN	_	Number=Sing	_	_	_	_
23	gamma	_	NOUN	_	Number=Sing	_	_	_	_
24	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	detection	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	specific	_	ADJ	_	Degree=Pos	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	DNA	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	binding	_	VERB	_	Number=Sing	_	_	_	_
38	activity	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
41	extracts	_	NOUN	_	Number=Plur	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	as	_	SCONJ	_	_	_	_	_	_
44	determined	_	VERB	_	Degree=Pos	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	gel	_	NOUN	_	Number=Sing	_	_	_	_
47	mobility	_	NOUN	_	Number=Sing	_	_	_	_
48	shift	_	NOUN	_	Number=Sing	_	_	_	_
49	assays	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	response	_	NOUN	_	Number=Sing	_	_	_	_
3	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	at	_	ADV	_	_	_	_	_	_
5	least	_	ADV	_	Degree=Sup	_	_	_	_
6	120	_	NUM	_	NumType=Card	_	_	_	_
7	min	_	NOUN	_	Number=Plur	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	evident	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	supershift	_	ADJ	_	Degree=Pos	_	_	_	_
13	experiments	_	NOUN	_	Number=Plur	_	_	_	_
14	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	complex	_	NOUN	_	Number=Sing	_	_	_	_
22	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	both	_	CCONJ	_	_	_	_	_	_
24	RelA	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	p50	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Accordingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	immunoblot	_	ADJ	_	Degree=Pos	_	_	_	_
4	experiments	_	NOUN	_	Number=Plur	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	amongst	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	Rel	_	NOUN	_	Number=Sing	_	_	_	_
4	proteins	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	RelA	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	p50	_	NOUN	_	Number=Sing	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	mobilized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
14	following	_	VERB	_	VerbForm=Ger	_	_	_	_
15	microglial	_	ADJ	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	beta	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	25	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	35	_	NUM	_	NumType=Card	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	plus	_	CCONJ	_	_	_	_	_	_
27	IFN	_	PROPN	_	Number=Sing	_	_	_	_
28	gamma	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Higher	_	ADJ	_	Degree=Cmp	_	_	_	_
2	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	25	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	SYM	_	_	_	_	_	_
9	35	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	effective	_	ADJ	_	Degree=Pos	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	themselves	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs|Reflex=Yes	_	_	_	_
15	in	_	SCONJ	_	_	_	_	_	_
16	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	both	_	CCONJ	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	N9	_	PROPN	_	Number=Sing	_	_	_	_
27	microglial	_	ADJ	_	Degree=Pos	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	line	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	rat	_	NOUN	_	Number=Sing	_	_	_	_
33	primary	_	ADJ	_	Degree=Pos	_	_	_	_
34	microglia	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	as	_	ADV	_	_	_	_	_	_
37	well	_	ADV	_	Degree=Pos	_	_	_	_
38	as	_	ADP	_	_	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	human	_	ADJ	_	Degree=Pos	_	_	_	_
41	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	purposes	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	comparison	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	microglia	_	NOUN	_	Number=Sing	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
12	LPS	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	known	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	inducer	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	expected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	LPS	_	PROPN	_	Number=Sing	_	_	_	_
5	strongly	_	ADV	_	_	_	_	_	_
6	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	formation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	DNA	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	activities	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	one	_	NUM	_	NumType=Card	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	RelA	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	p50	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	LPS	_	NOUN	_	Number=Sing	_	_	_	_
3	response	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	more	_	ADV	_	_	_	_	_	_
7	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	as	_	SCONJ	_	_	_	_	_	_
10	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	already	_	ADV	_	_	_	_	_	_
13	evident	_	ADJ	_	Degree=Pos	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	40	_	NUM	_	NumType=Card	_	_	_	_
16	min	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	sustained	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	up	_	ADP	_	_	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	3	_	NUM	_	NumType=Card	_	_	_	_
24	h	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Collectively	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	findings	_	NOUN	_	Number=Plur	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	might	_	AUX	_	VerbForm=Fin	_	_	_	_
13	constitute	_	VERB	_	VerbForm=Inf	_	_	_	_
14	one	_	NUM	_	NumType=Card	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
18	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	genes	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	microglia	_	NOUN	_	Number=Sing	_	_	_	_
30	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	beta	_	NOUN	_	Number=Sing	_	_	_	_
34	peptides	_	NOUN	_	Number=Plur	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	IFN	_	PROPN	_	Number=Sing	_	_	_	_
37	gamma	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	or	_	CCONJ	_	_	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	LPS	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011866	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Multiple	_	ADJ	_	Degree=Pos	_	_	_	_
2	prolactin	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	G1	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	S	_	PROPN	_	Number=Sing	_	_	_	_
10	phase	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	interferon	_	NOUN	_	Number=Sing	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	interferon	_	NOUN	_	Number=Sing	_	_	_	_
3	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	IRF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	early	_	ADJ	_	Degree=Pos	_	_	_	_
19	G1	_	NOUN	_	Number=Sing	_	_	_	_
20	phase	_	NOUN	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	S	_	NOUN	_	Number=Sing	_	_	_	_
25	phase	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	inducible	_	ADJ	_	Number=Sing	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	PRL	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	rat	_	NOUN	_	Number=Sing	_	_	_	_
32	Nb2	_	NOUN	_	Number=Sing	_	_	_	_
33	T	_	NOUN	_	Number=Sing	_	_	_	_
34	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	PRL	_	NOUN	_	Number=Sing	_	_	_	_
8	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IRF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
18	cloned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	rat	_	NOUN	_	Number=Sing	_	_	_	_
21	IRF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	functionally	_	ADV	_	_	_	_	_	_
27	characterized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	IRF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	promoter	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	into	_	ADP	_	_	_	_	_	_
4	Nb2	_	PROPN	_	Number=Sing	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	1.7	_	NUM	_	NumType=Card	_	_	_	_
9	kilobases	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	kb	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	IRF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	5	_	NUM	_	NumType=Card	_	_	_	_
18	'-	_	PUNCT	_	_	_	_	_	_
19	flanking	_	VERB	_	VerbForm=Ger	_	_	_	_
20	DNA	_	PROPN	_	Number=Sing	_	_	_	_
21	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
25	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
26	transferase	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	CAT	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	reporter	_	NOUN	_	Number=Sing	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	mediated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	30	_	NUM	_	NumType=Card	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	fold	_	NOUN	_	Number=Sing	_	_	_	_
37	induction	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	CAT	_	NOUN	_	Number=Sing	_	_	_	_
40	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
41	activity	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	response	_	NOUN	_	Number=Sing	_	_	_	_
44	to	_	ADP	_	_	_	_	_	_
45	24	_	NUM	_	NumType=Card	_	_	_	_
46	h	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	PRL	_	NOUN	_	Number=Sing	_	_	_	_
49	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	mutants	_	NOUN	_	Number=Plur	_	_	_	_
3	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	1.3	_	NUM	_	NumType=Card	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	0.6	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	0.2	_	NUM	_	NumType=Card	_	_	_	_
10	kb	_	NUM	_	Number=Sing	_	_	_	_
11	5	_	NUM	_	NumType=Card	_	_	_	_
12	'-	_	PUNCT	_	_	_	_	_	_
13	flanking	_	NOUN	_	Number=Sing	_	_	_	_
14	DNA	_	PROPN	_	Number=Sing	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	incrementally	_	ADV	_	_	_	_	_	_
17	less	_	ADV	_	Degree=Cmp	_	_	_	_
18	transcriptionally	_	ADV	_	_	_	_	_	_
19	active	_	ADJ	_	Degree=Pos	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	although	_	SCONJ	_	_	_	_	_	_
22	0.2	_	NUM	_	NumType=Card	_	_	_	_
23	kb	_	NOUN	_	Number=Sing	_	_	_	_
24	still	_	ADV	_	_	_	_	_	_
25	mediated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	12	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	fold	_	NOUN	_	Number=Sing	_	_	_	_
30	induction	_	NOUN	_	Number=Sing	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	PRL	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1.7	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	0.2	_	NUM	_	NumType=Card	_	_	_	_
9	kb	_	NOUN	_	Number=Sing	_	_	_	_
10	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
14	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	PRL	_	NOUN	_	Number=Sing	_	_	_	_
22	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
30	PRL	_	NOUN	_	Number=Sing	_	_	_	_
31	response	_	NOUN	_	Number=Sing	_	_	_	_
32	elements	_	NOUN	_	Number=Plur	_	_	_	_
33	may	_	AUX	_	VerbForm=Fin	_	_	_	_
34	require	_	VERB	_	VerbForm=Inf	_	_	_	_
35	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	interaction	_	NOUN	_	Number=Sing	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	promoter	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
41	elements	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	assaying	_	VERB	_	VerbForm=Ger	_	_	_	_
3	CAT	_	NOUN	_	Number=Sing	_	_	_	_
4	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	across	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	24	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	h	_	NOUN	_	Number=Sing	_	_	_	_
11	PRL	_	NOUN	_	Number=Sing	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	time	_	NOUN	_	Number=Sing	_	_	_	_
14	course	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	able	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	assign	_	VERB	_	VerbForm=Inf	_	_	_	_
21	G1	_	PROPN	_	Number=Sing	_	_	_	_
22	vs	_	ADP	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	S	_	PART	_	_	_	_	_	_
2	phase	_	NOUN	_	Number=Sing	_	_	_	_
3	PRL	_	NOUN	_	Number=Sing	_	_	_	_
4	responses	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	IRF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	different	_	ADJ	_	Degree=Pos	_	_	_	_
13	regions	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	IRF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	5	_	NUM	_	NumType=Card	_	_	_	_
20	'-	_	PUNCT	_	_	_	_	_	_
21	flanking	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	DNA	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	0.2	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kb	_	NOUN	_	Number=Sing	_	_	_	_
5	IRF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	CAT	_	NOUN	_	Number=Sing	_	_	_	_
8	construct	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	PRL	_	NOUN	_	Number=Sing	_	_	_	_
13	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
14	during	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	G1	_	NOUN	_	Number=Sing	_	_	_	_
17	phase	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	cycle	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	1.7	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kb	_	NOUN	_	Number=Sing	_	_	_	_
8	IRF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CAT	_	NOUN	_	Number=Sing	_	_	_	_
11	construct	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	inducible	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	PRL	_	NOUN	_	Number=Sing	_	_	_	_
16	during	_	ADP	_	_	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	G1	_	PROPN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	S	_	DET	_	Number=Sing	_	_	_	_
21	phase	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	cycle	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Hence	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	PRL	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	IRF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	separate	_	ADJ	_	Degree=Pos	_	_	_	_
21	PRL	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
24	elements	_	NOUN	_	Number=Plur	_	_	_	_
25	:	_	PUNCT	_	_	_	_	_	_
26	elements	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
30	0.2	_	NUM	_	NumType=Card	_	_	_	_
31	kb	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	IRF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	promoter	_	NOUN	_	Number=Sing	_	_	_	_
38	region	_	NOUN	_	Number=Sing	_	_	_	_
39	act	_	NOUN	_	Number=Sing	_	_	_	_
40	during	_	ADP	_	_	_	_	_	_
41	early	_	ADJ	_	Degree=Pos	_	_	_	_
42	activation	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	elements	_	NOUN	_	Number=Plur	_	_	_	_
46	between	_	ADP	_	_	_	_	_	_
47	0.2	_	NUM	_	NumType=Card	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	1.7	_	NUM	_	NumType=Card	_	_	_	_
50	kb	_	NUM	_	Number=Sing	_	_	_	_
51	act	_	NOUN	_	Number=Sing	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	concert	_	NOUN	_	Number=Sing	_	_	_	_
54	with	_	ADP	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
57	0.2	_	NUM	_	NumType=Card	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	kb	_	NOUN	_	Number=Sing	_	_	_	_
60	region	_	NOUN	_	Number=Sing	_	_	_	_
61	during	_	ADP	_	_	_	_	_	_
62	S	_	PROPN	_	Number=Sing	_	_	_	_
63	phase	_	NOUN	_	Number=Sing	_	_	_	_
64	progression	_	NOUN	_	Number=Sing	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011874	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	women	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	breast	_	NOUN	_	Number=Sing	_	_	_	_
8	cancer	_	NOUN	_	Number=Sing	_	_	_	_
9	exhibit	_	NOUN	_	Number=Sing	_	_	_	_
10	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	several	_	ADJ	_	Degree=Pos	_	_	_	_
15	signaling	_	ADJ	_	Number=Sing	_	_	_	_
16	molecules	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
4	molecules	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
7	blood	_	NOUN	_	Number=Sing	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	women	_	NOUN	_	Number=Plur	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	breast	_	NOUN	_	Number=Sing	_	_	_	_
15	cancer	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	6	_	NUM	_	NumType=Card	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	14	_	NUM	_	NumType=Card	_	_	_	_
5	patients	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	displayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
12	ability	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	translocate	_	VERB	_	VerbForm=Inf	_	_	_	_
15	NFeB	_	PROPN	_	Number=Sing	_	_	_	_
16	p65	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	Rel	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	A	_	X	_	_	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	following	_	VERB	_	VerbForm=Ger	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	observation	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	made	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	despite	_	ADP	_	_	_	_	_	_
6	normal	_	ADJ	_	Degree=Pos	_	_	_	_
7	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	Rel	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	detected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	abnormally	_	ADV	_	_	_	_	_	_
5	low	_	ADJ	_	Degree=Pos	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	signaling	_	VERB	_	Number=Sing	_	_	_	_
10	molecules	_	NOUN	_	Number=Plur	_	_	_	_
11	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	TCR	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	zeta	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	ZAP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	70	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	p56lck	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	4	_	NUM	_	NumType=Card	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	14	_	NUM	_	NumType=Card	_	_	_	_
28	breast	_	NOUN	_	Number=Sing	_	_	_	_
29	cancer	_	NOUN	_	Number=Sing	_	_	_	_
30	patients	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	i.e.	_	X	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	defects	_	NOUN	_	Number=Plur	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
37	signaling	_	VERB	_	Number=Sing	_	_	_	_
38	molecules	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	6	_	NUM	_	NumType=Card	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	14	_	NUM	_	NumType=Card	_	_	_	_
8	patients	_	NOUN	_	Number=Plur	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	dual	_	ADJ	_	Degree=Pos	_	_	_	_
17	specificity	_	NOUN	_	Number=Sing	_	_	_	_
18	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	map	_	NOUN	_	Number=Sing	_	_	_	_
21	kinase	_	NOUN	_	Number=Sing	_	_	_	_
22	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	MKP	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	MKP	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	inactivates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	MAP	_	NOUN	_	Number=Sing	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	therefore	_	ADV	_	_	_	_	_	_
9	may	_	AUX	_	VerbForm=Fin	_	_	_	_
10	interfere	_	VERB	_	VerbForm=Inf	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	c	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	jun	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	more	_	ADV	_	Degree=Cmp	_	_	_	_
6	signaling	_	ADJ	_	Degree=Pos	_	_	_	_
7	molecules	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	9	_	NUM	_	NumType=Card	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	14	_	NUM	_	NumType=Card	_	_	_	_
14	patients	_	NOUN	_	Number=Plur	_	_	_	_
15	;	_	PUNCT	_	_	_	_	_	_
16	however	_	ADV	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	only	_	ADV	_	_	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	patients	_	NOUN	_	Number=Plur	_	_	_	_
21	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	T	_	PART	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	all	_	DET	_	_	_	_	_	_
27	5	_	NUM	_	NumType=Card	_	_	_	_
28	defects	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	implications	_	NOUN	_	Number=Plur	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	detection	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	potentially	_	ADV	_	_	_	_	_	_
10	dysfunctional	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	patients	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	cancer	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	example	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	only	_	ADV	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	signaling	_	NOUN	_	Number=Sing	_	_	_	_
10	molecule	_	NOUN	_	Number=Sing	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	allow	_	VERB	_	VerbForm=Inf	_	_	_	_
13	patients	_	NOUN	_	Number=Plur	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	significant	_	ADJ	_	Degree=Pos	_	_	_	_
16	defects	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
19	signaling	_	VERB	_	Number=Sing	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	go	_	VERB	_	VerbForm=Inf	_	_	_	_
22	unnoticed	_	ADJ	_	Degree=Pos	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	despite	_	ADP	_	_	_	_	_	_
4	impaired	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	Rel	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	translocation	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	capable	_	ADJ	_	Degree=Pos	_	_	_	_
14	of	_	SCONJ	_	_	_	_	_	_
15	transcribing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_
20	Impairments	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	translocation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	Rel	_	NOUN	_	Number=Sing	_	_	_	_
26	-B	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
29	further	_	ADV	_	_	_	_	_	_
30	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	NFKB	_	PROPN	_	Number=Sing	_	_	_	_
34	family	_	NOUN	_	Number=Sing	_	_	_	_
35	members	_	NOUN	_	Number=Plur	_	_	_	_
36	Rel	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	A	_	PROPN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	Rel	_	PROPN	_	Number=Sing	_	_	_	_
41	-B	_	PROPN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
44	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
45	not	_	PART	_	_	_	_	_	_
46	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
47	for	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	transcription	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	IL	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	2	_	NUM	_	NumType=Card	_	_	_	_
54	in	_	ADP	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
57	T	_	NOUN	_	Number=Sing	_	_	_	_
58	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
59	of	_	ADP	_	_	_	_	_	_
60	patients	_	NOUN	_	Number=Plur	_	_	_	_
61	with	_	ADP	_	_	_	_	_	_
62	breast	_	NOUN	_	Number=Sing	_	_	_	_
63	cancer	_	NOUN	_	Number=Sing	_	_	_	_
64	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011876	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Potent	_	ADJ	_	Degree=Pos	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	replication	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	antiinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	alkaloid	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	cepharanthine	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	chronically	_	ADV	_	_	_	_	_	_
17	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Cepharanthine	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	biscoclaurine	_	NOUN	_	Number=Sing	_	_	_	_
5	alkaloid	_	NOUN	_	Number=Sing	_	_	_	_
6	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	Stephania	_	PROPN	_	Number=Sing	_	_	_	_
9	cepharantha	_	PROPN	_	Number=Sing	_	_	_	_
10	Hayata	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	have	_	VERB	_	VerbForm=Inf	_	_	_	_
17	antiinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	antiallergic	_	ADJ	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	immunomodulatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	activities	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	vivo	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	several	_	ADJ	_	Degree=Pos	_	_	_	_
3	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
7	stresses	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	involved	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	HIV	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	infection	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
23	effects	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	cepharanthine	_	NOUN	_	Number=Sing	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	tumor	_	NOUN	_	Number=Sing	_	_	_	_
28	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	TNF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	alpha	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
39	12	_	NUM	_	NumType=Card	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	myristate	_	NOUN	_	Number=Sing	_	_	_	_
42	13	_	NUM	_	NumType=Card	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	acetate	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	PMA	_	PROPN	_	Number=Sing	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	HIV	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	1	_	NUM	_	NumType=Card	_	_	_	_
53	replication	_	NOUN	_	Number=Sing	_	_	_	_
54	in	_	ADP	_	_	_	_	_	_
55	chronically	_	ADV	_	_	_	_	_	_
56	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
57	cell	_	NOUN	_	Number=Sing	_	_	_	_
58	lines	_	NOUN	_	Number=Plur	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	chronically	_	ADV	_	_	_	_	_	_
3	HIV	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	lines	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	U1	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	ACH	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	lymphocytic	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	TNF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	PMA	_	PROPN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	presence	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	various	_	ADJ	_	Degree=Pos	_	_	_	_
39	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	compound	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	replication	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	p24	_	NUM	_	Number=Sing	_	_	_	_
9	antigen	_	NOUN	_	Number=Sing	_	_	_	_
10	level	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	cepharanthine	_	NOUN	_	Number=Sing	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	HIV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	long	_	ADJ	_	Degree=Pos	_	_	_	_
11	terminal	_	NOUN	_	Number=Sing	_	_	_	_
12	repeat	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	LTR	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	also	_	ADV	_	_	_	_	_	_
32	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Cepharanthine	_	PROPN	_	Number=Sing	_	_	_	_
2	dose	_	AUX	_	Number=Sing	_	_	_	_
3	dependently	_	ADV	_	_	_	_	_	_
4	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	HIV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	replication	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	TNF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	PMA	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	U1	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	ACH	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	50	_	NUM	_	NumType=Card	_	_	_	_
3	%	_	SYM	_	Number=Sing	_	_	_	_
4	effective	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
7	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	0.016	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	2.2	_	NUM	_	NumType=Card	_	_	_	_
12	microg	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	ml	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	PMA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	U1	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	respectively	_	ADV	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Cepharanthine	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	LTR	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	cepharanthine	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	highly	_	ADV	_	_	_	_	_	_
9	potent	_	ADJ	_	Degree=Pos	_	_	_	_
10	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	replication	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	chronically	_	ADV	_	_	_	_	_	_
19	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	line	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	ADP	_	_	_	_	_	_
2	biscoclaurine	_	NOUN	_	Number=Sing	_	_	_	_
3	alkaloids	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	cepharanthine	_	NOUN	_	Number=Sing	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	major	_	ADJ	_	Degree=Pos	_	_	_	_
10	component	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	widely	_	ADV	_	_	_	_	_	_
14	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	treatment	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	patients	_	NOUN	_	Number=Plur	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	various	_	ADJ	_	Degree=Pos	_	_	_	_
22	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	diseases	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	Japan	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	cepharanthine	_	NOUN	_	Number=Sing	_	_	_	_
28	should	_	AUX	_	VerbForm=Fin	_	_	_	_
29	be	_	AUX	_	VerbForm=Inf	_	_	_	_
30	further	_	ADV	_	_	_	_	_	_
31	pursued	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	chemotherapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
35	potential	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	HIV	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	patients	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011877	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Stat	_	PROPN	_	Number=Sing	_	_	_	_
4	5b	_	NUM	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
7	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
8	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	ability	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	ErbB	_	PROPN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
16	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Self	_	NOUN	_	Number=Sing	_	_	_	_
2	renewal	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	normal	_	ADJ	_	Degree=Pos	_	_	_	_
5	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
6	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	c-ErbB	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	whereas	_	SCONJ	_	_	_	_	_	_
17	other	_	ADJ	_	Degree=Pos	_	_	_	_
18	receptors	_	NOUN	_	Number=Plur	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	c	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	Kit	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	Epo	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	R	_	X	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
29	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
30	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	address	_	VERB	_	VerbForm=Inf	_	_	_	_
3	possible	_	ADJ	_	Degree=Pos	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	could	_	AUX	_	VerbForm=Fin	_	_	_	_
7	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	selective	_	ADJ	_	Degree=Pos	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	c-ErbB	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	ability	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
20	receptors	_	NOUN	_	Number=Plur	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	different	_	ADJ	_	Degree=Pos	_	_	_	_
25	members	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	Stat	_	PROPN	_	Number=Sing	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	family	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Ligand	_	NOUN	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c-ErbB	_	NOUN	_	Number=Sing	_	_	_	_
5	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
8	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	DNA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	reporter	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	Stat	_	PROPN	_	Number=Sing	_	_	_	_
20	5b	_	NUM	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	ligand	_	ADJ	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	c	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Kit	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	unable	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
14	any	_	DET	_	_	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
17	effects	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	same	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	DNA	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Stat	_	PROPN	_	Number=Sing	_	_	_	_
13	5b	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
19	reporter	_	NOUN	_	Number=Sing	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
3	findings	_	NOUN	_	Number=Plur	_	_	_	_
4	correlate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	perfectly	_	ADV	_	_	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	selective	_	ADJ	_	Degree=Pos	_	_	_	_
9	ability	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	c	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	ErbB	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	cause	_	VERB	_	VerbForm=Inf	_	_	_	_
16	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	self	_	NOUN	_	Number=Sing	_	_	_	_
18	renewal	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
21	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011879	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	TR2	_	NOUN	_	Number=Sing	_	_	_	_
5	orphan	_	NOUN	_	Degree=Pos	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	element	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	initiation	_	NOUN	_	Number=Sing	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	simian	_	ADJ	_	Degree=Pos	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	40	_	NUM	_	NumType=Card	_	_	_	_
19	major	_	ADJ	_	Degree=Pos	_	_	_	_
20	late	_	ADJ	_	Degree=Pos	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	[	_	PUNCT	_	_	_	_	_	_
23	published	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	erratum	_	NOUN	_	Number=Sing	_	_	_	_
25	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	J	_	PROPN	_	Number=Sing	_	_	_	_
28	Biol	_	PROPN	_	Number=Sing	_	_	_	_
29	Chem	_	PROPN	_	Number=Sing	_	_	_	_
30	1995	_	NUM	_	NumType=Card	_	_	_	_
31	Nov	_	PROPN	_	Number=Sing	_	_	_	_
32	3;270	_	NUM	_	NumType=Card	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	44):26721	_	NUM	_	NumType=Card	_	_	_	_
35	]	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	DNA	_	NOUN	_	Number=Sing	_	_	_	_
3	response	_	NOUN	_	Number=Sing	_	_	_	_
4	element	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	TR2RE	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	SV40	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	TR2	_	PROPN	_	Number=Sing	_	_	_	_
13	orphan	_	NOUN	_	Number=Sing	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	member	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	steroid	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
23	hormone	_	NOUN	_	Number=Sing	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
29	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	simian	_	ADJ	_	Degree=Pos	_	_	_	_
33	virus	_	NOUN	_	Number=Sing	_	_	_	_
34	40	_	NUM	_	NumType=Card	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	SV40	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	+55	_	NUM	_	NumType=Card	_	_	_	_
39	region	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	nucleotide	_	NOUN	_	Number=Sing	_	_	_	_
42	numbers	_	NOUN	_	Number=Plur	_	_	_	_
43	368-389	_	NUM	_	NumType=Card	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	5'-	_	NUM	_	NumType=Card	_	_	_	_
46	GTTAAGGTTCGTAGGTCATGGA	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	3	_	NUM	_	NumType=Card	_	_	_	_
49	'	_	PUNCT	_	_	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	using	_	VERB	_	VerbForm=Ger	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	vitro	_	NOUN	_	Number=Sing	_	_	_	_
9	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	TR2	_	PROPN	_	Number=Sing	_	_	_	_
11	orphan	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
16	mass	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	67	_	NUM	_	NumType=Card	_	_	_	_
19	kilodaltons	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	high	_	ADJ	_	Degree=Pos	_	_	_	_
27	affinity	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
30	constant	_	ADJ	_	Degree=Pos	_	_	_	_
31	=	_	SYM	_	_	_	_	_	_
32	9	_	NUM	_	NumType=Card	_	_	_	_
33	nM	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
37	DNA	_	PROPN	_	Number=Sing	_	_	_	_
38	sequence	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	swap	_	NOUN	_	Number=Sing	_	_	_	_
4	experiments	_	NOUN	_	Number=Plur	_	_	_	_
5	using	_	VERB	_	VerbForm=Ger	_	_	_	_
6	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
7	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	transferase	_	NOUN	_	Number=Sing	_	_	_	_
10	assay	_	NOUN	_	Number=Sing	_	_	_	_
11	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	androgen	_	NOUN	_	Number=Sing	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	activities	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	SV40	_	NOUN	_	Number=Sing	_	_	_	_
21	early	_	ADJ	_	Degree=Pos	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	via	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	interaction	_	NOUN	_	Number=Sing	_	_	_	_
26	between	_	ADP	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	TR2RE	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	SV40	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	chimeric	_	ADJ	_	Degree=Pos	_	_	_	_
34	receptor	_	NOUN	_	Number=Sing	_	_	_	_
35	AR	_	NOUN	_	Number=Sing	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	TR2	_	NOUN	_	Number=Sing	_	_	_	_
38	/	_	PUNCT	_	_	_	_	_	_
39	AR	_	NOUN	_	Number=Sing	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	DNA	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	binding	_	VERB	_	Number=Sing	_	_	_	_
45	domain	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	TR2	_	PROPN	_	Number=Sing	_	_	_	_
49	orphan	_	NOUN	_	Number=Sing	_	_	_	_
50	receptor	_	NOUN	_	Number=Sing	_	_	_	_
51	flanked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
52	by	_	ADP	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	N	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	terminal	_	NOUN	_	Number=Sing	_	_	_	_
57	and	_	CCONJ	_	_	_	_	_	_
58	androgen	_	ADJ	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	binding	_	VERB	_	Number=Sing	_	_	_	_
61	domains	_	NOUN	_	Number=Plur	_	_	_	_
62	of	_	ADP	_	_	_	_	_	_
63	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
64	androgen	_	NOUN	_	Degree=Pos	_	_	_	_
65	receptor	_	NOUN	_	Number=Sing	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	TR2RE	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	SV40	_	NOUN	_	Number=Sing	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	function	_	VERB	_	VerbForm=Inf	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	repressor	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	activities	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	SV40	_	NOUN	_	Number=Sing	_	_	_	_
21	early	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	late	_	ADJ	_	Degree=Pos	_	_	_	_
24	promoters	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	TR2RE	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	SV40	_	NOUN	_	Number=Sing	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
14	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	natural	_	ADJ	_	Degree=Pos	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	element	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	TR2	_	PROPN	_	Number=Sing	_	_	_	_
22	orphan	_	NOUN	_	Number=Sing	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	may	_	AUX	_	VerbForm=Fin	_	_	_	_
26	function	_	VERB	_	VerbForm=Inf	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	repressor	_	NOUN	_	Number=Sing	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	SV40	_	NOUN	_	Number=Sing	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011880	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	T	_	DET	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	priming	_	NOUN	_	Number=Sing	_	_	_	_
4	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	SCONJ	_	_	_	_	_	_
11	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	repetitive	_	ADJ	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	priming	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	many	_	ADJ	_	Degree=Pos	_	_	_	_
15	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	such	_	ADJ	_	Degree=Pos	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	not	_	ADV	_	_	_	_	_	_
25	others	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	such	_	ADJ	_	Degree=Pos	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2	_	X	_	_	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_
33	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
34	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
35	underlying	_	VERB	_	Degree=Pos	_	_	_	_
36	selective	_	ADJ	_	Degree=Pos	_	_	_	_
37	expression	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	T	_	PROPN	_	Number=Sing	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
44	poorly	_	ADV	_	_	_	_	_	_
45	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	priming	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CD4	_	PROPN	_	Number=Sing	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	selectively	_	ADV	_	_	_	_	_	_
11	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	relative	_	ADV	_	_	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
26	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
27	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	proteins	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	vivo	_	PROPN	_	Number=Sing	_	_	_	_
6	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	priming	_	VERB	_	Number=Sing	_	_	_	_
9	markedly	_	ADV	_	_	_	_	_	_
10	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	engagement	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	P0	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	P1	_	NOUN	_	Number=Sing	_	_	_	_
21	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	binding	_	VERB	_	Number=Sing	_	_	_	_
24	elements	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	4	_	NUM	_	NumType=Card	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	each	_	DET	_	_	_	_	_	_
4	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
5	P	_	NOUN	_	Number=Sing	_	_	_	_
6	element	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	essential	_	ADJ	_	Degree=Pos	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	primed	_	ADJ	_	Degree=Pos	_	_	_	_
3	CD4	_	PROPN	_	Number=Sing	_	_	_	_

1	T	_	NUM	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	more	_	ADJ	_	Degree=Cmp	_	_	_	_
5	NFAT1	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	support	_	VERB	_	VerbForm=Inf	_	_	_	_
8	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
9	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	than	_	ADP	_	_	_	_	_	_
14	unprimed	_	ADJ	_	Degree=Pos	_	_	_	_
15	CD4	_	PROPN	_	Number=Sing	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	while	_	SCONJ	_	_	_	_	_	_
20	activator	_	NOUN	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	activator	_	NOUN	_	Number=Sing	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	both	_	DET	_	_	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	types	_	NOUN	_	Number=Plur	_	_	_	_
35	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	similar	_	ADJ	_	Degree=Pos	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	wild	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	NFAT1	_	PROPN	_	Number=Sing	_	_	_	_
8	substantially	_	ADV	_	_	_	_	_	_
9	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	unprimed	_	ADJ	_	Degree=Pos	_	_	_	_
17	CD4	_	PROPN	_	Number=Sing	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	NFAT1	_	NOUN	_	Number=Sing	_	_	_	_
23	may	_	AUX	_	VerbForm=Fin	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	limiting	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	4	_	NUM	_	NumType=Card	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	type	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	form	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NFAT1	_	PROPN	_	Number=Sing	_	_	_	_
8	acts	_	NOUN	_	Number=Plur	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	negative	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	reducing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	4	_	NUM	_	NumType=Card	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	primed	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
23	CD4	_	PROPN	_	Number=Sing	_	_	_	_
24	T	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	confirming	_	VERB	_	VerbForm=Ger	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	importance	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
32	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	4	_	NUM	_	NumType=Card	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	effector	_	NOUN	_	Number=Sing	_	_	_	_
42	T	_	NOUN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	NFAT1	_	PROPN	_	Number=Sing	_	_	_	_
2	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	major	_	ADJ	_	Degree=Pos	_	_	_	_
7	NFAT	_	ADJ	_	Number=Sing	_	_	_	_
8	family	_	NOUN	_	Number=Sing	_	_	_	_
9	member	_	NOUN	_	Number=Sing	_	_	_	_
10	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	initial	_	ADJ	_	Degree=Pos	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	4	_	NUM	_	NumType=Card	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	primed	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
22	CD4	_	PROPN	_	Number=Sing	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011881	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Host	_	ADJ	_	Number=Sing	_	_	_	_
2	defense	_	NOUN	_	Number=Sing	_	_	_	_
3	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
4	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	microbial	_	ADJ	_	Degree=Pos	_	_	_	_
7	lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	toll	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	like	_	ADJ	_	Degree=Pos	_	_	_	_
12	receptors	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	generation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	immunity	_	NOUN	_	Number=Sing	_	_	_	_
8	against	_	ADP	_	_	_	_	_	_
9	many	_	ADJ	_	Degree=Pos	_	_	_	_
10	infectious	_	ADJ	_	Degree=Pos	_	_	_	_
11	pathogens	_	NOUN	_	Number=Plur	_	_	_	_
12	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	12	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	SYM	_	_	_	_	_	_
22	12	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	key	_	ADJ	_	Degree=Pos	_	_	_	_
27	signal	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	innate	_	ADJ	_	Degree=Pos	_	_	_	_
31	immune	_	NOUN	_	Number=Sing	_	_	_	_
32	system	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Yet	_	CCONJ	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	many	_	ADJ	_	Degree=Pos	_	_	_	_
5	pathogens	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	molecules	_	NOUN	_	Number=Plur	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	12	_	NUM	_	NumType=Card	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
23	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	so	_	ADV	_	_	_	_	_	_
25	remain	_	VERB	_	VerbForm=Inf	_	_	_	_
26	undefined	_	ADJ	_	Degree=Pos	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	microbial	_	ADJ	_	Degree=Pos	_	_	_	_
7	lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	potent	_	ADJ	_	Degree=Pos	_	_	_	_
10	stimulators	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	12	_	NUM	_	NumType=Card	_	_	_	_
15	production	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	induction	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	Toll	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	like	_	ADJ	_	Degree=Pos	_	_	_	_
29	receptors	_	NOUN	_	Number=Plur	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	TLRs	_	NOUN	_	Number=Plur	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
3	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	TLR	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
10	nitric	_	ADJ	_	Degree=Pos	_	_	_	_
11	oxide	_	NOUN	_	Number=Sing	_	_	_	_
12	synthase	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	production	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	nitric	_	ADJ	_	Number=Sing	_	_	_	_
18	oxide	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	powerful	_	ADJ	_	Degree=Pos	_	_	_	_
22	microbicidal	_	ADJ	_	Degree=Pos	_	_	_	_
23	pathway	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TLRs	_	NOUN	_	Number=Plur	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	microbial	_	ADJ	_	Degree=Pos	_	_	_	_
6	lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	innate	_	ADJ	_	Degree=Pos	_	_	_	_
10	defense	_	NOUN	_	Number=Sing	_	_	_	_
11	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
12	against	_	ADP	_	_	_	_	_	_
13	infectious	_	ADJ	_	Degree=Pos	_	_	_	_
14	pathogens	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011883	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	10	_	NUM	_	NumType=Card	_	_	_	_
7	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	suppress	_	NOUN	_	Number=Sing	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	different	_	ADJ	_	Degree=Pos	_	_	_	_
13	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	previous	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	10	_	NUM	_	NumType=Card	_	_	_	_
16	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
17	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	LPS	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
26	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	beta	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	6	_	NUM	_	NumType=Card	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	8	_	NUM	_	NumType=Card	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	tumor	_	NOUN	_	Number=Sing	_	_	_	_
43	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
44	factor	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	TNF	_	PROPN	_	Number=Sing	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	alpha	_	NOUN	_	Number=Sing	_	_	_	_
50	by	_	ADP	_	_	_	_	_	_
51	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
52	gene	_	NOUN	_	Number=Sing	_	_	_	_
53	transcription	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	now	_	ADV	_	_	_	_	_	_
12	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
17	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	LPS	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	TNF	_	PROPN	_	Number=Sing	_	_	_	_
22	alpha	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	10	_	NUM	_	NumType=Card	_	_	_	_
27	inhibits	_	VERB	_	Number=Plur	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	transcription	_	NOUN	_	Number=Sing	_	_	_	_
43	factor	_	NOUN	_	Number=Sing	_	_	_	_
44	involved	_	ADJ	_	Degree=Pos	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
50	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
51	genes	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	including	_	VERB	_	VerbForm=Ger	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	AP	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	AP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	GR	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	CREB	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	Oct	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	Sp	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	not	_	PART	_	_	_	_	_	_
34	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	10	_	NUM	_	NumType=Card	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	selective	_	ADJ	_	Degree=Pos	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	10	_	NUM	_	NumType=Card	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	kappa	_	PROPN	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	rapidly	_	ADV	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	dose	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
21	manner	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	correlates	_	VERB	_	Number=Plur	_	_	_	_
24	well	_	ADV	_	Degree=Pos	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	10	_	NUM	_	NumType=Card	_	_	_	_
29	's	_	PART	_	_	_	_	_	_
30	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
31	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
32	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
33	activity	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	terms	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	both	_	CCONJ	_	_	_	_	_	_
38	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	dose	_	NOUN	_	Number=Sing	_	_	_	_
41	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	compounds	_	NOUN	_	Number=Plur	_	_	_	_
4	such	_	ADJ	_	Degree=Pos	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	tosylphenylalanyl	_	ADJ	_	Degree=Pos	_	_	_	_
7	chloromethyl	_	NOUN	_	Number=Sing	_	_	_	_
8	ketone	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	pyrrolidinedithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	selectively	_	ADV	_	_	_	_	_	_
16	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	block	_	NOUN	_	Number=Sing	_	_	_	_
22	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	LPS	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	kappa	_	PROPN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	important	_	ADJ	_	Degree=Pos	_	_	_	_
18	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	10	_	NUM	_	NumType=Card	_	_	_	_
23	suppression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	another	_	DET	_	_	_	_	_	_
6	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	little	_	ADJ	_	Degree=Pos	_	_	_	_
17	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
18	effect	_	NOUN	_	Number=Sing	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	LPS	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	examination	_	NOUN	_	Number=Sing	_	_	_	_
3	reveals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	unlike	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	enhances	_	NOUN	_	Number=Plur	_	_	_	_
15	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
16	degradation	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
21	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	10	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	inhibit	_	NOUN	_	Number=Sing	_	_	_	_
13	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	different	_	ADJ	_	Degree=Pos	_	_	_	_
17	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011885	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
4	genes	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cis	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
14	DNA	_	NOUN	_	Number=Sing	_	_	_	_
15	elements	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	respond	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	signals	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	initiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	recognition	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	antigen	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	antigen	_	NOUN	_	Number=Sing	_	_	_	_
14	presenting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	exert	_	VERB	_	VerbForm=Inf	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	effector	_	NOUN	_	Number=Sing	_	_	_	_
20	functions	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	immune	_	ADJ	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	responses	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	types	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	helper	_	NOUN	_	Number=Sing	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	Th	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	clones	_	NOUN	_	Number=Plur	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	Th1	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	Th2	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	basis	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	different	_	ADJ	_	Degree=Pos	_	_	_	_
23	patterns	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	secretion	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	determine	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	outcome	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	antigenic	_	ADJ	_	Degree=Pos	_	_	_	_
8	response	_	NOUN	_	Number=Sing	_	_	_	_
9	toward	_	ADP	_	_	_	_	_	_
10	humoral	_	ADJ	_	Number=Sing	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	immunity	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
3	genes	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	coordinately	_	ADV	_	_	_	_	_	_
6	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	upon	_	ADP	_	_	_	_	_	_
8	antigen	_	ADJ	_	Degree=Pos	_	_	_	_
9	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
17	common	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	all	_	DET	_	_	_	_	_	_
20	as	_	ADV	_	_	_	_	_	_
21	well	_	ADV	_	Degree=Pos	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	unique	_	ADJ	_	Degree=Pos	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	each	_	DET	_	_	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	most	_	ADJ	_	Degree=Sup	_	_	_	_
3	lymphokine	_	NOUN	_	Degree=Pos	_	_	_	_
4	genes	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	combination	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
10	esters	_	NOUN	_	Number=Plur	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
13	12	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	myristate	_	NOUN	_	Number=Sing	_	_	_	_
16	13	_	NUM	_	NumType=Card	_	_	_	_
17	acetate	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	PMA	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	calcium	_	NOUN	_	Number=Sing	_	_	_	_
23	ionophores	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	A23187	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
32	induction	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Yet	_	CCONJ	_	_	_	_	_	_
2	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
3	ester	_	NOUN	_	Number=Sing	_	_	_	_
4	alone	_	ADJ	_	_	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	calcium	_	NOUN	_	Number=Sing	_	_	_	_
7	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
8	alone	_	ADV	_	_	_	_	_	_
9	produce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	several	_	ADJ	_	Degree=Pos	_	_	_	_
11	lymphokines	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	production	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
8	colony	_	NOUN	_	Number=Sing	_	_	_	_
9	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	GM	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	CSF	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	completely	_	ADV	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	two	_	NUM	_	NumType=Card	_	_	_	_
22	signals	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	cis	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	spanning	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	GM	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	CSF	_	PROPN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	positions	_	NOUN	_	Number=Plur	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	95	_	NUM	_	NumType=Card	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	+	_	SYM	_	_	_	_	_	_
23	27	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	reporter	_	NOUN	_	VerbForm=Inf	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	transient	_	ADJ	_	Degree=Pos	_	_	_	_
33	transfection	_	NOUN	_	Number=Sing	_	_	_	_
34	assays	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	three	_	NUM	_	NumType=Card	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	referred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	GM2	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	GC	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	box	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
22	element	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	CLE0	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	GM2	_	PROPN	_	Number=Sing	_	_	_	_
2	defines	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	s	_	X	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	PMA	_	PROPN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	GM2	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	similar	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kB	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	GC	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	box	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	constitutively	_	ADV	_	_	_	_	_	_
10	bound	_	ADJ	_	Degree=Pos	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	CLEO	_	PROPN	_	Number=Sing	_	_	_	_
2	defines	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	s	_	X	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
12	optimum	_	ADJ	_	Degree=Pos	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	PMA	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	A23187	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Viral	_	ADJ	_	Degree=Pos	_	_	_	_
2	trans	_	NOUN	_	Number=Plur	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	activators	_	NOUN	_	Number=Plur	_	_	_	_
5	such	_	ADJ	_	Degree=Pos	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	Tax	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	E2	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	bovine	_	VERB	_	Number=Sing	_	_	_	_
25	papilloma	_	NOUN	_	Number=Sing	_	_	_	_
26	virus	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	BPV	_	PROPN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	other	_	ADJ	_	Degree=Pos	_	_	_	_
33	agents	_	NOUN	_	Number=Plur	_	_	_	_
34	which	_	PRON	_	PronType=Rel	_	_	_	_
35	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
37	gene	_	NOUN	_	Number=Sing	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	by	_	SCONJ	_	_	_	_	_	_
40	bypassing	_	VERB	_	VerbForm=Ger	_	_	_	_
41	T	_	NOUN	_	Number=Sing	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	receptor	_	NOUN	_	Number=Sing	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	TCR	_	NOUN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	mediated	_	VERB	_	Degree=Pos	_	_	_	_
48	signaling	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	trans	_	NOUN	_	Number=Plur	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	domain	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	E2	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	Tax	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	interchangeable	_	ADJ	_	Degree=Pos	_	_	_	_
12	although	_	SCONJ	_	_	_	_	_	_
13	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
14	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	no	_	DET	_	_	_	_	_	_
16	obvious	_	ADJ	_	Degree=Pos	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	homology	_	NOUN	_	Number=Sing	_	_	_	_
19	between	_	ADP	_	_	_	_	_	_
20	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	viral	_	ADJ	_	Degree=Pos	_	_	_	_
3	trans	_	NOUN	_	Number=Plur	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	activators	_	NOUN	_	Number=Plur	_	_	_	_
6	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	target	_	VERB	_	VerbForm=Inf	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	DNA	_	PROPN	_	Number=Sing	_	_	_	_
11	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	such	_	ADJ	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kB	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	cis	_	VERB	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	DNA	_	PROPN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
28	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	without	_	ADP	_	_	_	_	_	_
32	TCR	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
35	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011887	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cloning	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	ARE	_	PROPN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	AU	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	motif	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	display	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	procedure	_	NOUN	_	Number=Sing	_	_	_	_
3	suitable	_	ADJ	_	Degree=Pos	_	_	_	_
4	for	_	SCONJ	_	_	_	_	_	_
5	cloning	_	VERB	_	VerbForm=Ger	_	_	_	_
6	labile	_	NOUN	_	Number=Sing	_	_	_	_
7	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	AU	_	NOUN	_	Number=Sing	_	_	_	_
11	motifs	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	presented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	AU	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	DD	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	motifs	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	sequences	_	NOUN	_	Number=Plur	_	_	_	_
6	within	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	so	_	ADV	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	AU	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	rich	_	ADJ	_	Degree=Pos	_	_	_	_
14	elements	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	AREs	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	often	_	ADV	_	_	_	_	_	_
19	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	3	_	NUM	_	NumType=Card	_	_	_	_
22	'	_	PUNCT	_	_	_	_	_	_
23	untranslated	_	ADJ	_	Degree=Pos	_	_	_	_
24	regions	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	such	_	ADJ	_	Degree=Pos	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	proto	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	transcription	_	NOUN	_	Number=Sing	_	_	_	_
37	factors	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	AU	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	DD	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	AU	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	motif	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	differential	_	ADJ	_	Number=Sing	_	_	_	_
12	display	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	permits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	identification	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	ARE	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	differentially	_	ADV	_	_	_	_	_	_
23	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	after	_	ADP	_	_	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	applied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
7	blood	_	NOUN	_	Number=Sing	_	_	_	_
8	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	clone	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	isolate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	59	_	NUM	_	NumType=Card	_	_	_	_
17	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
18	fragments	_	NOUN	_	Number=Plur	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Fourteen	_	NUM	_	NumType=Card	_	_	_	_
2	percent	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	isolated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
5	fragments	_	NOUN	_	Number=Plur	_	_	_	_
6	belong	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	already	_	ADV	_	_	_	_	_	_
9	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	certainly	_	ADV	_	_	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	transduction	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factors	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	remaining	_	ADJ	_	Degree=Pos	_	_	_	_
3	86	_	NUM	_	NumType=Card	_	_	_	_
4	%	_	SYM	_	Number=Sing	_	_	_	_
5	correspond	_	ADJ	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	92	_	NUM	_	NumType=Card	_	_	_	_
12	%	_	SYM	_	Number=Sing	_	_	_	_
13	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
15	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	differentially	_	ADV	_	_	_	_	_	_
19	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	efficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	system	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	notion	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	numerous	_	ADJ	_	Degree=Pos	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	falling	_	VERB	_	VerbForm=Ger	_	_	_	_
17	into	_	ADP	_	_	_	_	_	_
18	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
19	categories	_	NOUN	_	Number=Plur	_	_	_	_
20	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	unidentified	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
25	can	_	AUX	_	VerbForm=Fin	_	_	_	_
26	be	_	AUX	_	VerbForm=Inf	_	_	_	_
27	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	method	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1998	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011889	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Role	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	ascorbate	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	tumour	_	NOUN	_	Number=Sing	_	_	_	_
13	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	product	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	ascorbate	_	ADJ	_	Degree=Pos	_	_	_	_
6	oxidation	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	ascorbate	_	NOUN	_	Number=Sing	_	_	_	_
10	free	_	ADJ	_	Degree=Pos	_	_	_	_
11	radical	_	ADJ	_	Degree=Pos	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	AFR	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	biological	_	ADJ	_	Degree=Pos	_	_	_	_
19	systems	_	NOUN	_	Number=Plur	_	_	_	_
20	mainly	_	ADV	_	_	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	oxidant	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	through	_	ADP	_	_	_	_	_	_
27	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	role	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	plasma	_	NOUN	_	Number=Sing	_	_	_	_
32	membrane	_	NOUN	_	Number=Sing	_	_	_	_
33	redox	_	NOUN	_	Number=Sing	_	_	_	_
34	system	_	NOUN	_	Number=Sing	_	_	_	_
35	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	different	_	ADJ	_	Degree=Pos	_	_	_	_
37	effects	_	NOUN	_	Number=Plur	_	_	_	_
38	on	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	ascorbate	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	AFR	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	dehydroascorbate	_	ADJ	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	DHA	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
27	T-cells	_	PROPN	_	Number=Sing	_	_	_	_
28	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	tumour	_	NOUN	_	Number=Sing	_	_	_	_
31	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
32	factor	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	alpha	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	TNF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	alpha	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
7	mobility	_	NOUN	_	Number=Sing	_	_	_	_
8	shift	_	NOUN	_	Number=Sing	_	_	_	_
9	assays	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	ascorbate	_	NOUN	_	Number=Sing	_	_	_	_
13	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	TNF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	ascorbate	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
7	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
8	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
9	IkBalpha	_	PROPN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	degradation	_	NOUN	_	Number=Sing	_	_	_	_
12	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	completely	_	ADV	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	capacity	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	DNA	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	potentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	HIV	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	long	_	ADJ	_	Degree=Pos	_	_	_	_
40	terminal	_	NOUN	_	Number=Sing	_	_	_	_
41	repeat	_	NOUN	_	Number=Sing	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	TNF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	alpha	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
50	cells	_	NOUN	_	Number=Plur	_	_	_	_
51	but	_	CCONJ	_	_	_	_	_	_
52	not	_	PART	_	_	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	cells	_	NOUN	_	Number=Plur	_	_	_	_
55	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
56	with	_	ADP	_	_	_	_	_	_
57	PMA	_	PROPN	_	Number=Sing	_	_	_	_
58	plus	_	CCONJ	_	_	_	_	_	_
59	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	AFR	_	PROPN	_	Number=Sing	_	_	_	_
2	behaves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	like	_	ADP	_	_	_	_	_	_
4	ascorbate	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	while	_	SCONJ	_	_	_	_	_	_
7	DHA	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	ascorbate	_	ADJ	_	Degree=Pos	_	_	_	_
10	phosphate	_	NOUN	_	Number=Sing	_	_	_	_
11	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	new	_	ADJ	_	Degree=Pos	_	_	_	_
5	evidence	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	possible	_	ADJ	_	Degree=Pos	_	_	_	_
9	relationship	_	NOUN	_	Number=Sing	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	electron	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	transport	_	NOUN	_	Number=Sing	_	_	_	_
18	system	_	NOUN	_	Number=Sing	_	_	_	_
19	at	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	plasma	_	NOUN	_	Number=Sing	_	_	_	_
22	membrane	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	ascorbate	_	NOUN	_	Number=Sing	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	free	_	ADJ	_	Degree=Pos	_	_	_	_
28	radical	_	ADJ	_	Degree=Pos	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	redox	_	ADJ	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011891	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	interferon	_	NOUN	_	Number=Sing	_	_	_	_
4	beta	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	vitro	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	novel	_	NOUN	_	Number=Sing	_	_	_	_
18	TH	_	NOUN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	interferon	_	NOUN	_	Number=Sing	_	_	_	_
4	beta	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	beta	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	element	_	NOUN	_	Number=Sing	_	_	_	_
12	consists	_	VERB	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
15	enhanson	_	NOUN	_	Number=Sing	_	_	_	_
16	domains	_	NOUN	_	Number=Plur	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	targets	_	NOUN	_	Number=Plur	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	involved	_	ADJ	_	Degree=Pos	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	DNA	_	NOUN	_	Number=Sing	_	_	_	_
8	interactions	_	NOUN	_	Number=Plur	_	_	_	_
9	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
10	IFN	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	beta	_	NOUN	_	Number=Sing	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	positive	_	ADJ	_	Degree=Pos	_	_	_	_
16	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	domain	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	PRD	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	II	_	NUM	_	NumType=Card	_	_	_	_
22	binding	_	VERB	_	Number=Sing	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	purified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
28	ester	_	NOUN	_	Number=Sing	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
31	T-cells	_	PROPN	_	Number=Plur	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	from	_	ADP	_	_	_	_	_	_
34	IFN	_	ADJ	_	Number=Sing	_	_	_	_
35	primed	_	ADJ	_	Degree=Pos	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
38	/	_	PUNCT	_	_	_	_	_	_
39	polyinosinic	_	ADJ	_	Degree=Pos	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	polycytidylic	_	ADJ	_	Degree=Pos	_	_	_	_
42	acid	_	NOUN	_	Number=Sing	_	_	_	_
43	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
45	S3	_	PROPN	_	Number=Sing	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	From	_	ADP	_	_	_	_	_	_

1	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	major	_	ADJ	_	Degree=Pos	_	_	_	_
6	proteins	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	52	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	45	_	NUM	_	NumType=Card	_	_	_	_
11	kilodaltons	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	kD	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	copurified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	DNA	_	NOUN	_	Number=Sing	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whereas	_	SCONJ	_	_	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	four	_	NUM	_	NumType=Card	_	_	_	_
26	proteins	_	NOUN	_	Number=Plur	_	_	_	_
27	--	_	PUNCT	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	major	_	ADJ	_	Degree=Pos	_	_	_	_
30	protein	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	52	_	NUM	_	NumType=Card	_	_	_	_
33	kD	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	three	_	NUM	_	NumType=Card	_	_	_	_
36	minor	_	ADJ	_	Degree=Pos	_	_	_	_
37	proteins	_	NOUN	_	Number=Plur	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	82	_	NUM	_	NumType=Card	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	67	_	NUM	_	NumType=Card	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	43	_	NUM	_	NumType=Card	_	_	_	_
45	-	_	SYM	_	_	_	_	_	_
46	47	_	NUM	_	NumType=Card	_	_	_	_
47	kD	_	NOUN	_	Number=Plur	_	_	_	_
48	--	_	PUNCT	_	_	_	_	_	_
49	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
50	purified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Also	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	purified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	interacted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	AAGTGA	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	tetrahexamer	_	NOUN	_	Number=Sing	_	_	_	_
23	sequence	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	PRDI	_	PROPN	_	Number=Sing	_	_	_	_
27	domain	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	immunologically	_	ADV	_	_	_	_	_	_
5	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	IRF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1/ISGF2	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Uninduced	_	PROPN	_	Number=Sing	_	_	_	_
2	or	_	CCONJ	_	_	_	_	_	_
3	Sendai	_	PROPN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
7	extracts	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vitro	_	NOUN	_	Number=Sing	_	_	_	_
15	using	_	VERB	_	VerbForm=Ger	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	series	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	IFN	_	PROPN	_	Number=Sing	_	_	_	_
20	beta	_	NOUN	_	Number=Sing	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	deletions	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Deletions	_	NOUN	_	Number=Plur	_	_	_	_
2	upstream	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	PRDII	_	PROPN	_	Number=Sing	_	_	_	_
6	element	_	NOUN	_	Number=Sing	_	_	_	_
7	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	uninduced	_	ADJ	_	Degree=Pos	_	_	_	_
12	extract	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	predominantly	_	ADV	_	_	_	_	_	_
16	negative	_	ADJ	_	Degree=Pos	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	2	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	SYM	_	_	_	_	_	_
4	4	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	fold	_	NOUN	_	Number=Sing	_	_	_	_
7	increase	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	IFN	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	Sendai	_	PROPN	_	Number=Sing	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	extracts	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	deletion	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	PRDI	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	PRDII	_	NOUN	_	Number=Sing	_	_	_	_
28	elements	_	NOUN	_	Number=Plur	_	_	_	_
29	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	level	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	PRDII	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	tetrahexamer	_	NOUN	_	Number=Sing	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	added	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	extract	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	fold	_	NOUN	_	Number=Sing	_	_	_	_
19	increase	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	possible	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	IFN	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	beta	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	vitro	_	NOUN	_	Number=Sing	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	additional	_	ADJ	_	Degree=Pos	_	_	_	_
20	proteins	_	NOUN	_	Number=Plur	_	_	_	_
21	may	_	AUX	_	VerbForm=Fin	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	fully	_	ADV	_	_	_	_	_	_
26	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	IFN	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	beta	_	NOUN	_	Number=Sing	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011893	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cross	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
4	CD40	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	B	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	rapidly	_	ADV	_	_	_	_	_	_
9	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B.	_	VERB	_	_	_	_	_	_
15	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	surface	_	NOUN	_	Number=Sing	_	_	_	_
21	molecule	_	NOUN	_	Number=Sing	_	_	_	_
22	CD40	_	NOUN	_	Number=Sing	_	_	_	_
23	functions	_	NOUN	_	Number=Plur	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	B	_	NOUN	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	responses	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Cross	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
4	CD40	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	B	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	homotypic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	6	_	NUM	_	NumType=Card	_	_	_	_
18	production	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	combination	_	NOUN	_	Number=Sing	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	Ig	_	PROPN	_	Number=Sing	_	_	_	_
29	isotype	_	NOUN	_	Number=Sing	_	_	_	_
30	switching	_	VERB	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Tyrosine	_	PROPN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	shortly	_	ADV	_	_	_	_	_	_
7	after	_	ADP	_	_	_	_	_	_
8	engagement	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Little	_	ADV	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	about	_	SCONJ	_	_	_	_	_	_
5	how	_	ADV	_	PronType=Int	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	very	_	ADV	_	_	_	_	_	_
8	early	_	ADJ	_	Degree=Pos	_	_	_	_
9	events	_	NOUN	_	Number=Plur	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	CD40	_	PROPN	_	Number=Sing	_	_	_	_
13	cross	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
16	link	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
19	responses	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	PROPN	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	PROPN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	like	_	ADP	_	Degree=Pos	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factors	_	NOUN	_	Number=Plur	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	after	_	ADP	_	_	_	_	_	_
28	cross	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
31	CD40	_	NOUN	_	Number=Sing	_	_	_	_
32	on	_	SCONJ	_	_	_	_	_	_
33	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
34	human	_	ADJ	_	Degree=Pos	_	_	_	_
35	tonsillar	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	on	_	ADP	_	_	_	_	_	_
40	B	_	NOUN	_	Degree=Pos	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	lines	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	pathway	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	complexes	_	NOUN	_	Number=Plur	_	_	_	_
3	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
6	mobility	_	NOUN	_	Number=Sing	_	_	_	_
7	shift	_	NOUN	_	Number=Sing	_	_	_	_
8	assays	_	NOUN	_	Number=Plur	_	_	_	_
9	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	p50	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	p65	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	RelA	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	c	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	Rel	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	most	_	ADV	_	_	_	_	_	_
23	likely	_	ADJ	_	Degree=Pos	_	_	_	_
24	other	_	ADJ	_	Degree=Pos	_	_	_	_
25	components	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	transient	_	ADJ	_	Degree=Pos	_	_	_	_
4	transfection	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	cross	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
13	CD40	_	PROPN	_	Number=Sing	_	_	_	_
14	supports	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	define	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	system	_	NOUN	_	Number=Sing	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	intermediate	_	ADJ	_	Degree=Pos	_	_	_	_
13	event	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	CD40	_	PROPN	_	Number=Sing	_	_	_	_
16	signaling	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	CD40	_	PROPN	_	Number=Sing	_	_	_	_
22	pathway	_	NOUN	_	Number=Sing	_	_	_	_
23	can	_	AUX	_	VerbForm=Fin	_	_	_	_
24	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	B	_	ADJ	_	Degree=Pos	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	associated	_	VERB	_	Degree=Pos	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappa	_	NOUN	_	Number=Sing	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	consensus	_	NOUN	_	Number=Sing	_	_	_	_
39	sites	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011895	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Intranuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	delivery	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	functional	_	ADJ	_	Degree=Pos	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	70	_	NUM	_	NumType=Card	_	_	_	_
11	kDa	_	NOUN	_	Number=Sing	_	_	_	_
12	heat	_	NOUN	_	Number=Sing	_	_	_	_
13	shock	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	70	_	NUM	_	NumType=Card	_	_	_	_
3	kDa	_	NOUN	_	Number=Sing	_	_	_	_
4	heat	_	NOUN	_	Number=Sing	_	_	_	_
5	shock	_	NOUN	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	Hsp70	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	highly	_	ADV	_	_	_	_	_	_
13	conserved	_	ADJ	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	involved	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	SCONJ	_	_	_	_	_	_
19	chaperoning	_	VERB	_	VerbForm=Ger	_	_	_	_
20	proteins	_	NOUN	_	Number=Plur	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	various	_	ADJ	_	Degree=Pos	_	_	_	_
23	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
24	organelles	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	when	_	ADV	_	PronType=Int	_	_	_	_
6	added	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	exogenously	_	ADV	_	_	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	Hsp70	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	readily	_	ADV	_	_	_	_	_	_
14	imported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	into	_	ADP	_	_	_	_	_	_
16	both	_	CCONJ	_	_	_	_	_	_
17	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	compartments	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	type	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	fashion	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	exploited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	ability	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Hsp70	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	deliver	_	VERB	_	VerbForm=Inf	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	key	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
16	regulator	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	responses	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	fusion	_	NOUN	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	composed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	C	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	terminal	_	NOUN	_	Number=Sing	_	_	_	_
13	Hsp70	_	NOUN	_	Number=Sing	_	_	_	_
14	peptide	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	p50	_	NOUN	_	Number=Sing	_	_	_	_
18	subunit	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	directed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	into	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	could	_	AUX	_	VerbForm=Fin	_	_	_	_
32	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
33	DNA	_	PROPN	_	Number=Sing	_	_	_	_
34	specifically	_	ADV	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	Igkappa	_	PROPN	_	Number=Sing	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
42	production	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Hsp70	_	NOUN	_	Number=Sing	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	vehicle	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	intracytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	intranuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	delivery	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	DNA	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	thereby	_	ADV	_	_	_	_	_	_
27	control	_	VERB	_	VerbForm=Inf	_	_	_	_
28	immune	_	ADJ	_	Number=Sing	_	_	_	_
29	responses	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011899	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	negative	_	ADJ	_	Degree=Pos	_	_	_	_
3	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	glucocorticosteroid	_	ADJ	_	Degree=Pos	_	_	_	_
8	response	_	NOUN	_	Number=Sing	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	nGRE	_	X	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1beta	_	NOUN	_	Number=Sing	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	beta	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1beta	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	one	_	NUM	_	NumType=Card	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	most	_	ADV	_	_	_	_	_	_
15	important	_	ADJ	_	Degree=Pos	_	_	_	_
16	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	mediators	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	inflammatory	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	immunological	_	ADJ	_	Degree=Pos	_	_	_	_
23	diseases	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1beta	_	PROPN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	several	_	ADJ	_	Degree=Pos	_	_	_	_
15	years	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	few	_	ADJ	_	Degree=Pos	_	_	_	_
20	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	elements	_	NOUN	_	Number=Plur	_	_	_	_
22	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	discovered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	region	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	little	_	ADV	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	about	_	ADP	_	_	_	_	_	_
7	negative	_	ADJ	_	Degree=Pos	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1beta	_	PROPN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	level	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	play	_	VERB	_	VerbForm=Inf	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	important	_	ADJ	_	Degree=Pos	_	_	_	_
24	role	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
29	effects	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	negative	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	between	_	ADP	_	_	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	685	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	-	_	SYM	_	_	_	_	_	_
17	395	_	NUM	_	NumType=Card	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Within	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	19	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	bp	_	NOUN	_	Number=Sing	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	570	_	NUM	_	NumType=Card	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	552	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	DNase	_	NOUN	_	Number=Sing	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	footprinting	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	electromobility	_	NOUN	_	Number=Sing	_	_	_	_
28	shift	_	NOUN	_	Number=Sing	_	_	_	_
29	assay	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	consensus	_	NOUN	_	Number=Sing	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	negative	_	ADJ	_	Degree=Pos	_	_	_	_
7	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
8	response	_	NOUN	_	Number=Sing	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	nGRE	_	X	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	activator	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	noted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	within	_	ADP	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	footprint	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	2.5	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	fold	_	NOUN	_	Number=Sing	_	_	_	_
8	increase	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	when	_	ADV	_	PronType=Int	_	_	_	_
13	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	19	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	bp	_	NOUN	_	Number=Sing	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	deleted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	reporter	_	NOUN	_	Number=Sing	_	_	_	_
24	constructs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1beta	_	PROPN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	CAT	_	PROPN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1beta	_	PROPN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	SV40	_	PROPN	_	Number=Sing	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	/	_	PUNCT	_	_	_	_	_	_
38	CAT	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Dexamethasone	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	-	_	SYM	_	_	_	_	_	_
6	8	_	NUM	_	NumType=Card	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	M	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	repressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	chloramphenicol	_	NOUN	_	Number=Sing	_	_	_	_
12	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	CAT	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	75	_	NUM	_	NumType=Card	_	_	_	_
19	%	_	SYM	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	wild	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	type	_	NOUN	_	Number=Sing	_	_	_	_
25	fragment	_	NOUN	_	Number=Sing	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	not	_	ADV	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	deletion	_	NOUN	_	Number=Sing	_	_	_	_
31	mutant	_	NOUN	_	Number=Sing	_	_	_	_
32	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	19	_	NUM	_	NumType=Card	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	bp	_	NOUN	_	Number=Sing	_	_	_	_
37	site	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	about	_	ADV	_	_	_	_	_	_
5	150	_	NUM	_	NumType=Card	_	_	_	_
6	kD	_	NOUN	_	Number=Plur	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	bound	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	negative	_	ADJ	_	Degree=Pos	_	_	_	_
12	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	sequence	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	UV	_	PROPN	_	Number=Sing	_	_	_	_
18	cross	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	linking	_	VERB	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
5	description	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	negative	_	ADJ	_	Degree=Pos	_	_	_	_
9	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	region	_	NOUN	_	Number=Sing	_	_	_	_
11	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011900	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differences	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
4	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Response	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	signals	_	NOUN	_	Number=Plur	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	T	_	NUM	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	high	_	ADJ	_	Degree=Pos	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	replication	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	one	_	NUM	_	NumType=Card	_	_	_	_
17	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
18	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	conversion	_	NOUN	_	Number=Sing	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	latent	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	active	_	ADJ	_	Degree=Pos	_	_	_	_
26	viral	_	ADJ	_	Degree=Pos	_	_	_	_
27	infection	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	HIV	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	sequences	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	respond	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	signaling	_	NOUN	_	Number=Sing	_	_	_	_
13	events	_	NOUN	_	Number=Plur	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	long	_	ADJ	_	Degree=Pos	_	_	_	_
19	terminal	_	NOUN	_	Number=Sing	_	_	_	_
20	repeat	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	LTR	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	comprise	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
28	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	which	_	PRON	_	PronType=Rel	_	_	_	_
31	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	two	_	NUM	_	NumType=Card	_	_	_	_
33	conserved	_	VERB	_	Degree=Pos	_	_	_	_
34	binding	_	VERB	_	Number=Sing	_	_	_	_
35	sites	_	NOUN	_	Number=Plur	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
39	factor	_	NOUN	_	Number=Sing	_	_	_	_
40	kappa	_	NOUN	_	Number=Sing	_	_	_	_
41	B	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	NF	_	PROPN	_	Number=Sing	_	_	_	_
44	kappa	_	PROPN	_	Number=Sing	_	_	_	_
45	B	_	NOUN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	corresponding	_	VERB	_	Degree=Pos	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
8	retrovirus	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	HIV	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	conserved	_	NOUN	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	divergent	_	ADJ	_	Degree=Pos	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	HIV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	LTR	_	PROPN	_	Number=Sing	_	_	_	_
9	responds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	better	_	ADV	_	Degree=Cmp	_	_	_	_
11	than	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	LTR	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	signals	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	qualitative	_	ADJ	_	Degree=Pos	_	_	_	_
3	differences	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	T	_	DET	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	reproduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	only	_	ADV	_	_	_	_	_	_
15	when	_	ADV	_	PronType=Int	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	placed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	upstream	_	ADP	_	_	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	but	_	CCONJ	_	_	_	_	_	_
32	also	_	ADV	_	_	_	_	_	_
33	when	_	ADV	_	PronType=Int	_	_	_	_
34	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
35	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
36	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
37	switched	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	between	_	ADP	_	_	_	_	_	_
39	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
40	respective	_	ADJ	_	Degree=Pos	_	_	_	_
41	LTR	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	both	_	DET	_	_	_	_	_	_
13	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	sites	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	only	_	ADV	_	_	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	single	_	ADJ	_	Degree=Pos	_	_	_	_
27	conserved	_	VERB	_	Degree=Pos	_	_	_	_
28	site	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	HIV	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
35	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Instead	_	ADV	_	_	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	kappa	_	PROPN	_	Number=Sing	_	_	_	_
5	B	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	activator	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	binds	_	NOUN	_	Number=Plur	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	divergent	_	ADJ	_	Degree=Pos	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	HIV	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	differentially	_	ADV	_	_	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	T	_	NUM	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	signals	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	difference	_	NOUN	_	Number=Sing	_	_	_	_
23	may	_	AUX	_	VerbForm=Fin	_	_	_	_
24	account	_	VERB	_	VerbForm=Inf	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	longer	_	ADJ	_	Degree=Cmp	_	_	_	_
28	period	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	viral	_	ADJ	_	Degree=Pos	_	_	_	_
31	latency	_	NOUN	_	Number=Sing	_	_	_	_
32	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	HIV	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	than	_	ADP	_	_	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	HIV	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	infection	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011907	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Involvement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
6	p50/p65	_	NOUN	_	Number=Sing	_	_	_	_
7	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	pro-interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1beta	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	two	_	NUM	_	NumType=Card	_	_	_	_
19	subregions	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
23	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
24	element	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	-	_	SYM	_	_	_	_	_	_
5	3134	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	2729	_	NUM	_	NumType=Card	_	_	_	_
9	bp	_	NOUN	_	Number=Sing	_	_	_	_
10	upstream	_	NOUN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	pro-interleukin	_	NOUN	_	Number=Sing	_	_	_	_
19	1beta	_	PROPN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	proIL	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1beta	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	LPS	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
33	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
34	element	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	influence	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	sequences	_	NOUN	_	Number=Plur	_	_	_	_
10	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	between	_	ADP	_	_	_	_	_	_
12	-	_	SYM	_	_	_	_	_	_
13	3134	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	-	_	SYM	_	_	_	_	_	_
16	2987	_	NUM	_	NumType=Card	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	proIL	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1beta	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	LPS	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	Raw	_	PROPN	_	Number=Sing	_	_	_	_
32	264.7	_	NUM	_	NumType=Card	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
35	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	detail	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	transient	_	ADJ	_	Degree=Pos	_	_	_	_
6	transfection	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	fos	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CAT	_	NOUN	_	Number=Sing	_	_	_	_
11	constructs	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	serial	_	ADJ	_	Degree=Pos	_	_	_	_
15	5'-	_	NUM	_	_	_	_	_	_
16	deletion	_	NOUN	_	Number=Sing	_	_	_	_
17	mutations	_	NOUN	_	Number=Plur	_	_	_	_
18	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	region	_	NOUN	_	Number=Sing	_	_	_	_
22	between	_	ADP	_	_	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	3134	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	-	_	SYM	_	_	_	_	_	_
27	3059	_	NUM	_	NumType=Card	_	_	_	_
28	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	induction	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	transcription	_	NOUN	_	Number=Sing	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	LPS	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	shift	_	NOUN	_	Number=Sing	_	_	_	_
3	assay	_	NOUN	_	Number=Sing	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
7	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
8	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	partial	_	ADJ	_	Degree=Pos	_	_	_	_
11	sequences	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	latter	_	ADJ	_	Degree=Pos	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	extracts	_	NOUN	_	Number=Plur	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	sites	_	NOUN	_	Number=Plur	_	_	_	_
27	between	_	ADP	_	_	_	_	_	_
28	-	_	SYM	_	_	_	_	_	_
29	3110	_	NUM	_	NumType=Card	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	-	_	SYM	_	_	_	_	_	_
32	3090	_	NUM	_	NumType=Card	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	between	_	ADP	_	_	_	_	_	_
35	-	_	SYM	_	_	_	_	_	_
36	3079	_	NUM	_	NumType=Card	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	-	_	SYM	_	_	_	_	_	_
39	3059	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	specific	_	ADJ	_	Degree=Pos	_	_	_	_
3	bindings	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	time	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	LPS	_	NOUN	_	Number=Sing	_	_	_	_
8	dose	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	supershift	_	NOUN	_	Number=Sing	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	using	_	VERB	_	VerbForm=Ger	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
9	against	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	both	_	DET	_	_	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	complexes	_	NOUN	_	Number=Plur	_	_	_	_
17	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	components	_	NOUN	_	Number=Plur	_	_	_	_
23	p50	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	p65	_	NUM	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	not	_	PART	_	_	_	_	_	_
30	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
31	other	_	ADJ	_	Degree=Pos	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
35	proteins	_	NOUN	_	Number=Plur	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	p52	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	c	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	Rel	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	Rel	_	NOUN	_	Number=Sing	_	_	_	_
44	B	_	NOUN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	AP	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	1	_	NUM	_	NumType=Card	_	_	_	_
50	proteins	_	NOUN	_	Number=Plur	_	_	_	_
51	(	_	PUNCT	_	_	_	_	_	_
52	c	_	NOUN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	Fos	_	PROPN	_	Number=Sing	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	C	_	PROPN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	Jun	_	PROPN	_	Number=Sing	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	,	_	PUNCT	_	_	_	_	_	_
61	CREB	_	PROPN	_	Number=Sing	_	_	_	_
62	or	_	CCONJ	_	_	_	_	_	_
63	C	_	PROPN	_	Number=Sing	_	_	_	_
64	/	_	PUNCT	_	_	_	_	_	_
65	EBPbeta	_	PROPN	_	Number=Sing	_	_	_	_
66	(	_	PUNCT	_	_	_	_	_	_
67	NF	_	PROPN	_	Number=Sing	_	_	_	_
68	-	_	PUNCT	_	_	_	_	_	_
69	IL6	_	NOUN	_	Number=Sing	_	_	_	_
70	)	_	PUNCT	_	_	_	_	_	_
71	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	either	_	DET	_	_	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	putative	_	ADJ	_	Degree=Pos	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	LPS	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	sites	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	between	_	ADP	_	_	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	3134	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	-	_	SYM	_	_	_	_	_	_
21	3059	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	critical	_	ADJ	_	Degree=Pos	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	proIL	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1beta	_	NOUN	_	Number=Sing	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1999	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011914	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	ATc	_	PROPN	_	Number=Sing	_	_	_	_
9	positively	_	ADV	_	_	_	_	_	_
10	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	replication	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Clinical	_	ADJ	_	Degree=Pos	_	_	_	_
2	deterioration	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	infection	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	levels	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	viral	_	ADJ	_	Degree=Pos	_	_	_	_
22	replication	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	burden	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
28	blood	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
31	organs	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	ensuing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	critical	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	replication	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	AT	_	ADP	_	_	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	replication	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	therefore	_	ADV	_	_	_	_	_	_
24	compelling	_	ADJ	_	Degree=Pos	_	_	_	_
25	given	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	tight	_	ADJ	_	Degree=Pos	_	_	_	_
28	correlation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	HIV	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
34	induction	_	NOUN	_	Number=Sing	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	T	_	NOUN	_	Number=Sing	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	activation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	certain	_	ADJ	_	Degree=Pos	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	AT	_	ADP	_	_	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	Rel	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	family	_	NOUN	_	Number=Sing	_	_	_	_
12	members	_	NOUN	_	Number=Plur	_	_	_	_
13	productively	_	ADV	_	_	_	_	_	_
14	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	elements	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	synergize	_	VERB	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	Tat	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	HIV	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
37	HIV	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	replication	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	T	_	PROPN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	link	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	critical	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	commitment	_	NOUN	_	Number=Sing	_	_	_	_
11	directly	_	ADV	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	HIV	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	replication	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011921	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	into	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
9	phenylarsine	_	NOUN	_	Number=Sing	_	_	_	_
10	oxide	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	aging	_	NOUN	_	Number=Sing	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	evidence	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	IkappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	degradation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	Factor	_	NOUN	_	Number=Sing	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	critical	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulator	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	several	_	ADJ	_	Degree=Pos	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	involved	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	immune	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
20	responses	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	variety	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	including	_	VERB	_	VerbForm=Ger	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	translocation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	active	_	ADJ	_	Degree=Pos	_	_	_	_
23	p65-50	_	NUM	_	NumType=Card	_	_	_	_
24	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	albeit	_	SCONJ	_	_	_	_	_	_
30	at	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
33	level	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	T	_	PROPN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	from	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	elderly	_	NOUN	_	Degree=Pos	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	DET	_	_	_	_	_	_
5	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	PAO	_	NOUN	_	Number=Sing	_	_	_	_
8	results	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	PROPN	_	Number=Sing	_	_	_	_
19	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	role	_	NOUN	_	Number=Sing	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	PAO	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
30	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
37	via	_	ADP	_	_	_	_	_	_
38	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
39	pathway	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	human	_	ADJ	_	Degree=Pos	_	_	_	_
42	T	_	NOUN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	aging	_	NOUN	_	Number=Sing	_	_	_	_
7	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	DMP	_	NOUN	_	Number=Sing	_	_	_	_
4	prior	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	treatment	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	PAO	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	TNF	_	PROPN	_	Number=Sing	_	_	_	_
11	abolishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	PAO	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	both	_	DET	_	_	_	_	_	_
23	young	_	ADJ	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	old	_	ADJ	_	Degree=Pos	_	_	_	_
26	donors	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	alike	_	ADJ	_	Degree=Pos	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	failure	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	degrade	_	VERB	_	VerbForm=Inf	_	_	_	_
10	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	cytosols	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	pretreated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	PAO	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	due	_	ADP	_	_	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	interference	_	NOUN	_	Number=Sing	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	alpha	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	not	_	ADV	_	_	_	_	_	_
38	due	_	ADP	_	_	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
41	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
42	effect	_	NOUN	_	Number=Sing	_	_	_	_
43	on	_	ADP	_	_	_	_	_	_
44	proteasomal	_	ADJ	_	Degree=Pos	_	_	_	_
45	degradation	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	collectively	_	ADV	_	_	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	PAO	_	PROPN	_	Number=Sing	_	_	_	_
7	interferes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	regulated	_	VERB	_	Degree=Pos	_	_	_	_
14	degradation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	TNF	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	without	_	SCONJ	_	_	_	_	_	_
25	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	chymotryptic	_	ADJ	_	Degree=Pos	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	independent	_	ADJ	_	Degree=Pos	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	age	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011923	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Defining	_	VERB	_	VerbForm=Ger	_	_	_	_
2	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
3	targets	_	NOUN	_	Number=Plur	_	_	_	_
4	by	_	SCONJ	_	_	_	_	_	_
5	using	_	VERB	_	VerbForm=Ger	_	_	_	_
6	adenovirus	_	NOUN	_	Number=Sing	_	_	_	_
7	:	_	PUNCT	_	_	_	_	_	_
8	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	destructive	_	ADJ	_	Degree=Pos	_	_	_	_
17	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	rheumatoid	_	ADJ	_	Degree=Pos	_	_	_	_
20	synovium	_	NOUN	_	Number=Sing	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	spares	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	mediators	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	rheumatoid	_	NOUN	_	Number=Sing	_	_	_	_
15	arthritis	_	NOUN	_	Number=Sing	_	_	_	_
16	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	long	_	ADV	_	Degree=Pos	_	_	_	_
18	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	subject	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	controversy	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	adenoviral	_	ADJ	_	Degree=Pos	_	_	_	_
5	technique	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
16	subunit	_	NOUN	_	Number=Sing	_	_	_	_
17	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	advantage	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	_	_	_	_	_
24	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
25	can	_	AUX	_	VerbForm=Fin	_	_	_	_
26	be	_	AUX	_	VerbForm=Inf	_	_	_	_
27	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	diseased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	tissue	_	NOUN	_	Number=Sing	_	_	_	_
32	itself	_	PRON	_	Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	>90	_	NUM	_	NumType=Card	_	_	_	_
36	%	_	SYM	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
40	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	T	_	NOUN	_	Number=Sing	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	spontaneous	_	ADJ	_	Degree=Pos	_	_	_	_
6	production	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	tumor	_	NOUN	_	Number=Sing	_	_	_	_
9	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	other	_	ADJ	_	Degree=Pos	_	_	_	_
14	pro-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	rheumatoid	_	ADJ	_	Degree=Pos	_	_	_	_
24	synovial	_	ADJ	_	Degree=Pos	_	_	_	_
25	tissue	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	contrast	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	main	_	ADJ	_	Degree=Pos	_	_	_	_
32	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
33	mediators	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	like	_	ADP	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	10	_	NUM	_	NumType=Card	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	-	_	SYM	_	_	_	_	_	_
41	11	_	NUM	_	NumType=Card	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	IL	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	receptor	_	NOUN	_	Number=Sing	_	_	_	_
49	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Of	_	ADP	_	_	_	_	_	_
2	even	_	ADV	_	_	_	_	_	_
3	more	_	ADJ	_	Degree=Cmp	_	_	_	_
4	interest	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
7	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	production	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	matrix	_	NOUN	_	Number=Sing	_	_	_	_
13	metalloproteinases	_	NOUN	_	Number=Plur	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	3	_	NUM	_	NumType=Card	_	_	_	_
17	while	_	SCONJ	_	_	_	_	_	_
18	not	_	ADV	_	_	_	_	_	_
19	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	tissue	_	NOUN	_	Number=Sing	_	_	_	_
22	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	rheumatoid	_	NOUN	_	Number=Sing	_	_	_	_
8	joint	_	NOUN	_	Number=Sing	_	_	_	_
9	thus	_	ADV	_	_	_	_	_	_
10	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	very	_	ADV	_	_	_	_	_	_
13	beneficial	_	ADJ	_	Degree=Pos	_	_	_	_
14	profile	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	reducing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	both	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
20	response	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	tissue	_	NOUN	_	Number=Sing	_	_	_	_
24	destruction	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	adenoviral	_	ADJ	_	Degree=Pos	_	_	_	_
3	technique	_	NOUN	_	Number=Sing	_	_	_	_
4	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	here	_	ADV	_	PronType=Dem	_	_	_	_
6	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	widespread	_	ADJ	_	Degree=Pos	_	_	_	_
8	applicability	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	allowing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
12	testing	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	effects	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	SCONJ	_	_	_	_	_	_
17	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	potential	_	ADJ	_	Degree=Pos	_	_	_	_
20	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
21	target	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	either	_	CCONJ	_	_	_	_	_	_
24	cultures	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	normal	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	diseased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	tissue	_	NOUN	_	Number=Sing	_	_	_	_
33	itself	_	PRON	_	Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011927	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	control	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
5	replication	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Barr	_	PROPN	_	Number=Sing	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	B	_	ADJ	_	Number=Sing	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	Review	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Uncontrolled	_	VERB	_	Degree=Pos	_	_	_	_
2	replication	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	harmful	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	host	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	disadvantageous	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Most	_	ADJ	_	Degree=Sup	_	_	_	_
2	viruses	_	NOUN	_	Number=Plur	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	compete	_	VERB	_	VerbForm=Inf	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	various	_	ADJ	_	Degree=Pos	_	_	_	_
9	immune	_	ADJ	_	Number=Sing	_	_	_	_
10	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	become	_	VERB	_	VerbForm=Inf	_	_	_	_
13	eliminated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	course	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	infection	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	only	_	ADV	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	time	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	infection	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	eradication	_	NOUN	_	Number=Sing	_	_	_	_
10	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	for	_	SCONJ	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	viruses	_	NOUN	_	Number=Plur	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	proliferate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	few	_	ADJ	_	Degree=Pos	_	_	_	_
3	viruses	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	like	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Herpesviruses	_	NOUN	_	Number=Plur	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	papillomaviruses	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	however	_	ADV	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	developed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	sophisticated	_	ADJ	_	Degree=Pos	_	_	_	_
18	strategy	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	SCONJ	_	_	_	_	_	_
20	persisting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	lifelong	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	usually	_	ADV	_	_	_	_	_	_
24	asymptomatically	_	ADV	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	host	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	hiding	_	VERB	_	VerbForm=Ger	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	immune	_	NOUN	_	Degree=Pos	_	_	_	_
33	system	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
36	infectious	_	ADJ	_	Degree=Pos	_	_	_	_
37	progeny	_	NOUN	_	Number=Sing	_	_	_	_
38	at	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	same	_	ADJ	_	Degree=Pos	_	_	_	_
41	time	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	strategy	_	NOUN	_	Number=Sing	_	_	_	_
3	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	separation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	latency	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	replication	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	either	_	CCONJ	_	_	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	time	_	NOUN	_	Number=Sing	_	_	_	_
17	due	_	ADP	_	_	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	spatial	_	ADJ	_	Degree=Pos	_	_	_	_
26	separation	_	NOUN	_	Number=Sing	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	result	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	different	_	ADJ	_	Degree=Pos	_	_	_	_
32	host	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	types	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	true	_	ADJ	_	Degree=Pos	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	Barr	_	PROPN	_	Number=Sing	_	_	_	_
9	virus	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	EBV	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	B	_	ADJ	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	pivotal	_	ADJ	_	Degree=Pos	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	life	_	NOUN	_	Number=Sing	_	_	_	_
13	cycle	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	former	_	ADJ	_	Degree=Pos	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	become	_	VERB	_	VerbForm=Inf	_	_	_	_
5	latently	_	ADV	_	_	_	_	_	_
6	infected	_	VERB	_	Degree=Pos	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	reservoir	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	vivo	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	whereas	_	SCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	latter	_	ADJ	_	Degree=Pos	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	permissive	_	ADJ	_	Degree=Pos	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
28	replication	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	replication	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	EBV	_	PROPN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	vivo	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	primarily	_	ADV	_	_	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	host	_	ADJ	_	Number=Sing	_	_	_	_
13	immune	_	ADJ	_	Degree=Pos	_	_	_	_
14	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
15	selecting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	permissive	_	ADJ	_	Degree=Pos	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	viral	_	ADJ	_	Degree=Pos	_	_	_	_
24	replication	_	NOUN	_	Number=Sing	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	result	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	particular	_	ADJ	_	Degree=Pos	_	_	_	_
31	set	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	factors	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	early	_	ADJ	_	Degree=Pos	_	_	_	_
12	genes	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	addition	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	lytic	_	ADJ	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	latent	_	ADJ	_	Degree=Pos	_	_	_	_
21	cycle	_	NOUN	_	Number=Sing	_	_	_	_
22	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	negatively	_	ADV	_	_	_	_	_	_
25	interfere	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	each	_	DET	_	_	_	_	_	_
28	other	_	ADJ	_	Degree=Pos	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	thus	_	ADV	_	_	_	_	_	_
31	link	_	NOUN	_	Number=Sing	_	_	_	_
32	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	viral	_	ADJ	_	Degree=Pos	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
37	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Disturbance	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	both	_	CCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	immune	_	ADJ	_	Degree=Pos	_	_	_	_
6	surveillance	_	NOUN	_	Number=Sing	_	_	_	_
7	as	_	ADV	_	_	_	_	_	_
8	well	_	ADV	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	viral	_	ADJ	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	result	_	VERB	_	VerbForm=Inf	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	EBV	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	disease	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011933	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	directs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	colony	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
19	colony	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	CBF	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	AML1	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
6	colony	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	colony	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	[	_	PUNCT	_	_	_	_	_	_
18	CSF	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	X	_	NumType=Card	_	_	_	_
21	]	_	PUNCT	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	different	_	ADJ	_	Degree=Pos	_	_	_	_
27	promoters	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	placental	_	ADJ	_	Degree=Pos	_	_	_	_
33	trophoblasts	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	CSF	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	tissue	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	B-	_	PUNCT	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	specific	_	ADJ	_	Degree=Pos	_	_	_	_
41	transcription	_	NOUN	_	Number=Sing	_	_	_	_
42	factor	_	NOUN	_	Number=Sing	_	_	_	_
43	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	D.-E.Zhang	_	PROPN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	C.J.Hetherington	_	PROPN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	H.-M.Chen	_	PROPN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	D.G.	_	PROPN	_	Number=Sing	_	_	_	_
53	Tenen	_	PROPN	_	Number=Sing	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	Mol.Cell	_	PROPN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Biol.14:373-381	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	1994	_	NUM	_	NumType=Card	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	tissue	_	NOUN	_	Number=Sing	_	_	_	_
7	specificity	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	sequences	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	region	_	NOUN	_	Number=Sing	_	_	_	_
19	II	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	bp	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	88	_	NUM	_	NumType=Card	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	59	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	lies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	10	_	NUM	_	NumType=Card	_	_	_	_
32	bp	_	NOUN	_	Number=Sing	_	_	_	_
33	upstream	_	NOUN	_	Number=Sing	_	_	_	_
34	from	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	binding	_	NOUN	_	Number=Sing	_	_	_	_
39	site	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	DNase	_	PROPN	_	Number=Sing	_	_	_	_
5	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	II	_	PROPN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	protected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	preferentially	_	ADV	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	confirmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	II	_	PROPN	_	NumType=Card	_	_	_	_
9	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	specifically	_	ADV	_	_	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	gel	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	complexes	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	Mono	_	PROPN	_	Number=Sing	_	_	_	_
7	A	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	Mono	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	formed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	separate	_	ADJ	_	Degree=Pos	_	_	_	_
16	sequence	_	NOUN	_	Number=Sing	_	_	_	_
17	elements	_	NOUN	_	Number=Plur	_	_	_	_
18	within	_	ADP	_	_	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	region	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Competition	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	supershift	_	NOUN	_	Number=Sing	_	_	_	_
4	experiments	_	NOUN	_	Number=Plur	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	Mono	_	PROPN	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	member	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	polyomavirus	_	PROPN	_	Number=Sing	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	core	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	CBF	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	family	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	includes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	AML1	_	PROPN	_	Number=Sing	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	product	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	while	_	SCONJ	_	_	_	_	_	_
40	Mono	_	PROPN	_	Number=Sing	_	_	_	_
41	A	_	PROPN	_	Number=Sing	_	_	_	_
42	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
45	complex	_	NOUN	_	Number=Sing	_	_	_	_
46	preferentially	_	ADV	_	_	_	_	_	_
47	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
50	cells	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Promoter	_	NOUN	_	Number=Sing	_	_	_	_
2	constructs	_	NOUN	_	Number=Plur	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	mutations	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	elements	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	no	_	ADV	_	_	_	_	_	_
11	longer	_	ADV	_	Degree=Cmp	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	specifically	_	ADV	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	multimerized	_	ADJ	_	Degree=Pos	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	II	_	NUM	_	NumType=Card	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	elements	_	NOUN	_	Number=Plur	_	_	_	_
8	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
14	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	not	_	ADV	_	_	_	_	_	_
22	other	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	types	_	NOUN	_	Number=Plur	_	_	_	_
25	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	B-	_	PUNCT	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	Mono	_	PROPN	_	Number=Sing	_	_	_	_
18	A	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	Mono	_	PROPN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	complexes	_	NOUN	_	Number=Plur	_	_	_	_
24	act	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	concert	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
29	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	specific	_	ADJ	_	Degree=Pos	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	CSF	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	receptor	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011936	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	cooperates	_	VERB	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	TNF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	latently	_	ADV	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	acutely	_	ADV	_	_	_	_	_	_
18	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
24	lineage	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	elevated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	HIV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	individuals	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	disease	_	NOUN	_	Number=Sing	_	_	_	_
19	progression	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	effects	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	10	_	NUM	_	NumType=Card	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	10	_	NUM	_	NumType=Card	_	_	_	_
5	alone	_	ADV	_	_	_	_	_	_
6	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	replication	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	presence	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	TNF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	10	_	NUM	_	NumType=Card	_	_	_	_
25	markedly	_	ADV	_	_	_	_	_	_
26	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	virion	_	NOUN	_	Number=Sing	_	_	_	_
28	production	_	NOUN	_	Number=Sing	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	chronically	_	ADV	_	_	_	_	_	_
32	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	line	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	U1	_	PROPN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	acutely	_	ADV	_	_	_	_	_	_
42	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Neutralizing	_	VERB	_	VerbForm=Ger	_	_	_	_
2	mAbs	_	NOUN	_	Number=Plur	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	10	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	PROPN	_	Number=Sing	_	_	_	_
11	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	both	_	DET	_	_	_	_	_	_
14	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	essential	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	generate	_	VERB	_	VerbForm=Inf	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
27	increase	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	virus	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	distinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
9	functionally	_	ADV	_	_	_	_	_	_
10	since	_	ADP	_	_	_	_	_	_
11	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	TNF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	attenuated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
19	cooperativity	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	while	_	SCONJ	_	_	_	_	_	_
22	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	10	_	NUM	_	NumType=Card	_	_	_	_
27	potentiated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
29	cooperativity	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	that	_	SCONJ	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	10	_	NUM	_	NumType=Card	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	TNF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	alpha	_	PROPN	_	Number=Sing	_	_	_	_
40	play	_	VERB	_	Number=Sing	_	_	_	_
41	different	_	ADJ	_	Degree=Pos	_	_	_	_
42	roles	_	NOUN	_	Number=Plur	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	virus	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	as	_	ADV	_	_	_	_	_	_
5	well	_	ADV	_	Degree=Pos	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	Ab	_	PROPN	_	Number=Sing	_	_	_	_
8	blocking	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	cytokine	_	ADJ	_	Number=Sing	_	_	_	_
11	secretion	_	NOUN	_	Number=Sing	_	_	_	_
12	studies	_	NOUN	_	Number=Plur	_	_	_	_
13	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	either	_	CCONJ	_	_	_	_	_	_
19	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
20	TNF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	10	_	NUM	_	NumType=Card	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	involved	_	ADJ	_	Degree=Pos	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	cooperativity	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	nor	_	CCONJ	_	_	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	up	_	ADJ	_	Degree=Pos	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	regulation	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	TNF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	alpha	_	NOUN	_	Number=Sing	_	_	_	_
44	receptors	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	combination	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	activating	_	VERB	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	AP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	activities	_	NOUN	_	Number=Plur	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	cooperated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
36	HIV	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	steady	_	ADJ	_	Degree=Pos	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	state	_	NOUN	_	Number=Sing	_	_	_	_
42	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
43	levels	_	NOUN	_	Number=Plur	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	enhance	_	VERB	_	Number=Sing	_	_	_	_
46	long	_	ADJ	_	Degree=Pos	_	_	_	_
47	terminal	_	NOUN	_	Number=Sing	_	_	_	_
48	repeat	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	transcription	_	NOUN	_	Number=Sing	_	_	_	_
52	through	_	ADP	_	_	_	_	_	_
53	activation	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	NF	_	PROPN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	kappa	_	NOUN	_	Number=Sing	_	_	_	_
59	B	_	NOUN	_	Number=Sing	_	_	_	_
60	binding	_	NOUN	_	Number=Sing	_	_	_	_
61	sites	_	NOUN	_	Number=Plur	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
64	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
65	IL	_	PROPN	_	Number=Sing	_	_	_	_
66	-	_	PUNCT	_	_	_	_	_	_
67	10	_	NUM	_	NumType=Card	_	_	_	_
68	effect	_	NOUN	_	Number=Sing	_	_	_	_
69	occurs	_	NOUN	_	Number=Plur	_	_	_	_
70	at	_	ADV	_	_	_	_	_	_
71	least	_	ADV	_	Degree=Sup	_	_	_	_
72	in	_	ADP	_	_	_	_	_	_
73	part	_	NOUN	_	Number=Sing	_	_	_	_
74	at	_	ADP	_	_	_	_	_	_
75	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
76	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
77	level	_	NOUN	_	Number=Sing	_	_	_	_
78	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	10	_	NUM	_	NumType=Card	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	addition	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	down	_	ADV	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
17	immune	_	ADJ	_	Number=Sing	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	may	_	AUX	_	VerbForm=Fin	_	_	_	_
25	also	_	ADV	_	_	_	_	_	_
26	play	_	VERB	_	VerbForm=Inf	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	role	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	TNF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	alpha	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	mediated	_	VERB	_	Degree=Pos	_	_	_	_
35	activation	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	HIV	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	replication	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
44	/	_	PUNCT	_	_	_	_	_	_
45	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
46	lineage	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011937	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	repression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
11	D3	_	NOUN	_	Number=Sing	_	_	_	_
12	:	_	PUNCT	_	_	_	_	_	_
13	direct	_	ADJ	_	Degree=Pos	_	_	_	_
14	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	complex	_	ADJ	_	Degree=Pos	_	_	_	_
22	formation	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	hormone	_	NOUN	_	Number=Sing	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	T-lymphocyte	_	PROPN	_	Number=Sing	_	_	_	_
2	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	1,25	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
9	D3	_	NOUN	_	Number=Sing	_	_	_	_
10	[	_	PUNCT	_	_	_	_	_	_
11	1,25	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	OH	_	INTJ	_	_	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	2D3	_	NUM	_	NumType=Card	_	_	_	_
16	]	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	active	_	ADJ	_	Degree=Pos	_	_	_	_
20	metabolite	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
23	D3	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	decrease	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	gamma	_	NOUN	_	Number=Sing	_	_	_	_
41	interferon	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
47	colony	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
50	factor	_	NOUN	_	Number=Sing	_	_	_	_
51	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
52	levels	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	1,25	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	OH	_	INTJ	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	2D3	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	VERB	_	Degree=Pos	_	_	_	_
12	repression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	cycloheximide	_	ADJ	_	Degree=Pos	_	_	_	_
18	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	direct	_	ADJ	_	Degree=Pos	_	_	_	_
26	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
27	repressive	_	ADJ	_	Degree=Pos	_	_	_	_
28	effect	_	NOUN	_	Number=Sing	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
37	D3	_	PROPN	_	Number=Sing	_	_	_	_
38	receptor	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	VDR	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	vitamin	_	ADJ	_	Number=Sing	_	_	_	_
5	D3	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	mediated	_	VERB	_	Degree=Pos	_	_	_	_
8	repression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	SCONJ	_	_	_	_	_	_
16	cotransfecting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	reporter	_	NOUN	_	Number=Sing	_	_	_	_
26	constructs	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	VDR	_	PROPN	_	Number=Sing	_	_	_	_
30	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
31	vector	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	DNA	_	PROPN	_	Number=Sing	_	_	_	_
35	binding	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	delineated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	element	_	NOUN	_	Number=Sing	_	_	_	_
5	conferring	_	VERB	_	VerbForm=Ger	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	DNA	_	PROPN	_	Number=Sing	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vitro	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	1,25	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	OH	_	INTJ	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	2D3	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	VERB	_	Degree=Pos	_	_	_	_
22	repression	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	vivo	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	short	_	ADJ	_	Degree=Pos	_	_	_	_
28	40	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	bp	_	NOUN	_	Number=Sing	_	_	_	_
31	region	_	NOUN	_	Number=Sing	_	_	_	_
32	encompassing	_	VERB	_	VerbForm=Ger	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	important	_	ADJ	_	Degree=Pos	_	_	_	_
35	positive	_	ADJ	_	Degree=Pos	_	_	_	_
36	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
37	element	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	AT	_	ADP	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	1	_	NUM	_	NumType=Card	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	which	_	PRON	_	PronType=Rel	_	_	_	_
46	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
47	bound	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	by	_	ADP	_	_	_	_	_	_
49	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
50	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	specific	_	ADJ	_	Degree=Pos	_	_	_	_
53	transcription	_	NOUN	_	Number=Sing	_	_	_	_
54	factor	_	NOUN	_	Number=Sing	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	as	_	ADV	_	_	_	_	_	_
59	well	_	ADV	_	Degree=Pos	_	_	_	_
60	as	_	ADP	_	_	_	_	_	_
61	by	_	ADP	_	_	_	_	_	_
62	AP	_	NOUN	_	Number=Sing	_	_	_	_
63	-	_	PUNCT	_	_	_	_	_	_
64	1	_	NUM	_	NumType=Card	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	VDR	_	PROPN	_	Number=Sing	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	mutants	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	unable	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	either	_	CCONJ	_	_	_	_	_	_
10	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	element	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	vitro	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	repress	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	vivo	_	NOUN	_	Number=Sing	_	_	_	_
20	;	_	PUNCT	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	VDR	_	PROPN	_	Number=Sing	_	_	_	_
23	DNA	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	binding	_	VERB	_	Number=Sing	_	_	_	_
26	domain	_	NOUN	_	Number=Sing	_	_	_	_
27	alone	_	ADV	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	however	_	ADV	_	_	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	bound	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	element	_	NOUN	_	Number=Sing	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	also	_	ADV	_	_	_	_	_	_
36	could	_	AUX	_	VerbForm=Fin	_	_	_	_
37	not	_	PART	_	_	_	_	_	_
38	repress	_	VERB	_	VerbForm=Inf	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	expression	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	VDR	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	repression	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	combining	_	VERB	_	VerbForm=Ger	_	_	_	_
3	partially	_	ADV	_	_	_	_	_	_
4	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	vitro	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	loss	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	bound	_	ADJ	_	Degree=Pos	_	_	_	_
16	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	AP	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	DNA	_	PROPN	_	Number=Sing	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	upon	_	ADP	_	_	_	_	_	_
25	inclusion	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	VDR	_	NOUN	_	Number=Sing	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	VDR	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
32	X	_	SYM	_	_	_	_	_	_
33	receptor	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Order	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	addition	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	off	_	ADP	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	rate	_	NOUN	_	Number=Sing	_	_	_	_
8	experiments	_	NOUN	_	Number=Plur	_	_	_	_
9	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	VDR	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
15	X	_	PROPN	_	_	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
18	blocks	_	NOUN	_	Number=Plur	_	_	_	_
19	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	AP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	complex	_	ADJ	_	Degree=Pos	_	_	_	_
25	formation	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	then	_	ADV	_	PronType=Dem	_	_	_	_
28	stably	_	ADV	_	_	_	_	_	_
29	associates	_	VERB	_	Number=Plur	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	AT	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	element	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	direct	_	ADJ	_	Degree=Pos	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	hormone	_	NOUN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	activators	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	may	_	AUX	_	VerbForm=Fin	_	_	_	_
19	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	mechanistic	_	ADJ	_	Degree=Pos	_	_	_	_
22	explanation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	SCONJ	_	_	_	_	_	_
24	how	_	ADV	_	PronType=Int	_	_	_	_
25	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
26	derivatives	_	NOUN	_	Number=Plur	_	_	_	_
27	can	_	AUX	_	VerbForm=Fin	_	_	_	_
28	act	_	VERB	_	VerbForm=Inf	_	_	_	_
29	as	_	ADP	_	_	_	_	_	_
30	potent	_	ADJ	_	Degree=Pos	_	_	_	_
31	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
32	agents	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011940	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Leukotriene	_	PROPN	_	Number=Sing	_	_	_	_

1	B4	_	PROPN	_	Number=Sing	_	_	_	_
2	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	c	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	fos	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	c	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	jun	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	leukotriene	_	NOUN	_	Number=Sing	_	_	_	_
8	B4	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	LTB4	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	potent	_	ADJ	_	Degree=Pos	_	_	_	_
15	lipid	_	ADJ	_	Degree=Pos	_	_	_	_
16	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	mediator	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	proto	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	oncogenes	_	NOUN	_	Number=Sing	_	_	_	_
27	c	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	jun	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	c	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	fos	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	looked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	modulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
13	specifically	_	ADV	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	AP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	element	_	NOUN	_	Number=Sing	_	_	_	_
20	after	_	ADP	_	_	_	_	_	_
21	LTB4	_	PROPN	_	Number=Sing	_	_	_	_
22	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	LTB4	_	PROPN	_	Number=Sing	_	_	_	_
2	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	c	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	fos	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	time	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	concentration	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	manner	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
3	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	constitutively	_	ADV	_	_	_	_	_	_
8	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	peripheral	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	blood	_	NOUN	_	Number=Sing	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	relatively	_	ADV	_	_	_	_	_	_
17	high	_	ADJ	_	Degree=Pos	_	_	_	_
18	levels	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	also	_	ADV	_	_	_	_	_	_
22	slightly	_	ADV	_	_	_	_	_	_
23	augmented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	LTB4	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	although	_	SCONJ	_	_	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	much	_	ADV	_	_	_	_	_	_
31	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
32	extent	_	NOUN	_	Number=Sing	_	_	_	_
33	than	_	ADP	_	_	_	_	_	_
34	c	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	fos	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	also	_	ADV	_	_	_	_	_	_
11	slightly	_	ADV	_	_	_	_	_	_
12	different	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
16	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
17	reaching	_	VERB	_	VerbForm=Ger	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	peak	_	NOUN	_	Number=Sing	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	15	_	NUM	_	NumType=Card	_	_	_	_
22	min	_	NOUN	_	Number=Plur	_	_	_	_
23	after	_	ADP	_	_	_	_	_	_
24	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	c	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	jun	_	NOUN	_	Number=Sing	_	_	_	_
29	at	_	ADP	_	_	_	_	_	_
30	30	_	NUM	_	NumType=Card	_	_	_	_
31	min	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	messages	_	NOUN	_	Number=Plur	_	_	_	_
3	rapidly	_	ADV	_	_	_	_	_	_
4	declined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	thereafter	_	ADV	_	_	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	Stability	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	LTB4	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	as	_	SCONJ	_	_	_	_	_	_
15	assessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	after	_	ADP	_	_	_	_	_	_
17	actinomycin	_	NOUN	_	Number=Sing	_	_	_	_
18	D	_	NOUN	_	Number=Sing	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	vitro	_	NOUN	_	Number=Sing	_	_	_	_
6	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	LTB4	_	PROPN	_	Number=Sing	_	_	_	_
9	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	c	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	fos	_	ADP	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	7	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	fold	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	c	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	jun	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	1.4-	_	NUM	_	NumType=Card	_	_	_	_
28	fold	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Resting	_	VERB	_	VerbForm=Ger	_	_	_	_
2	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	LTB4	_	PROPN	_	Number=Sing	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
22	AP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	LTB4	_	PROPN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	different	_	ADJ	_	Degree=Pos	_	_	_	_
12	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	yield	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	function	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factors	_	NOUN	_	Number=Plur	_	_	_	_
25	such	_	ADJ	_	Degree=Pos	_	_	_	_
26	as	_	ADP	_	_	_	_	_	_
27	AP	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	binding	_	NOUN	_	Number=Sing	_	_	_	_
32	proto	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
35	products	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011942	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Reactive	_	ADJ	_	Degree=Pos	_	_	_	_
2	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
3	intermediates	_	NOUN	_	Number=Plur	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	apparently	_	ADV	_	_	_	_	_	_
6	widely	_	ADV	_	_	_	_	_	_
7	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	messengers	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	HIV	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Hydrogen	_	ADJ	_	Degree=Pos	_	_	_	_
2	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	oxygen	_	ADJ	_	Degree=Pos	_	_	_	_
5	radicals	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	agents	_	NOUN	_	Number=Plur	_	_	_	_
8	commonly	_	ADV	_	_	_	_	_	_
9	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	during	_	ADP	_	_	_	_	_	_
11	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	processes	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	micromolar	_	ADJ	_	Degree=Pos	_	_	_	_
9	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	replication	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	line	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	potently	_	ADV	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	rapidly	_	ADV	_	_	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	H2O2	_	ADJ	_	Number=Sing	_	_	_	_
22	treatment	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
28	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
29	form	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	N-acetyl-L	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	cysteine	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	NAC	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	well	_	ADV	_	Degree=Pos	_	_	_	_
10	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	counteracts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	effects	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
18	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
19	intermediates	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	ROI	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	living	_	VERB	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	NAC	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	thiol	_	NOUN	_	Number=Sing	_	_	_	_
5	compounds	_	NOUN	_	Number=Plur	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	double	_	ADJ	_	Degree=Pos	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	RNA	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	calcium	_	NOUN	_	Number=Sing	_	_	_	_
24	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	TNF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	active	_	ADJ	_	Degree=Pos	_	_	_	_
31	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
32	ester	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	lectin	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
5	agents	_	NOUN	_	Number=Plur	_	_	_	_
6	thought	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
15	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
16	pathways	_	NOUN	_	Number=Plur	_	_	_	_
17	might	_	AUX	_	VerbForm=Fin	_	_	_	_
18	all	_	ADV	_	_	_	_	_	_
19	act	_	VERB	_	VerbForm=Inf	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	common	_	ADJ	_	Degree=Pos	_	_	_	_
23	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
24	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	ROI	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	ROI	_	PROPN	_	Number=Sing	_	_	_	_
2	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	messengers	_	NOUN	_	Number=Plur	_	_	_	_
7	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	directly	_	ADV	_	_	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	indirectly	_	ADV	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	release	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
16	subunit	_	NOUN	_	Number=Sing	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	PROPN	_	Number=Sing	_	_	_	_
24	B.	_	PROPN	_	Number=Sing	_	_	_	_
25	Document	_	NOUN	_	Number=Sing	_	_	_	_
26	0030011945	_	NUM	_	NumType=Card	_	_	_	_
27	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	early	_	ADJ	_	Degree=Pos	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	product	_	NOUN	_	Number=Sing	_	_	_	_
7	Egr	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	beta-chain	_	NOUN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	through	_	ADP	_	_	_	_	_	_
20	noncanonical	_	ADJ	_	Degree=Pos	_	_	_	_
21	Egr	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	sites	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	beta-chain	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	Rbeta	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	essential	_	ADJ	_	Degree=Pos	_	_	_	_
19	component	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	receptors	_	NOUN	_	Number=Plur	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	15	_	NUM	_	NumType=Card	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2Rbeta	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	constitutively	_	ADV	_	_	_	_	_	_
7	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	can	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	further	_	ADV	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	number	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	including	_	VERB	_	VerbForm=Ger	_	_	_	_
24	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
25	12	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	myristate	_	NOUN	_	Number=Sing	_	_	_	_
28	13	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	acetate	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	PMA	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	now	_	ADV	_	_	_	_	_	_
4	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	between	_	ADP	_	_	_	_	_	_
14	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	170	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	-	_	SYM	_	_	_	_	_	_
19	139	_	NUM	_	NumType=Card	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2Rbeta	_	PROPN	_	Number=Sing	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	Sp3	_	PROPN	_	Number=Sing	_	_	_	_
5	bound	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	'	_	PUNCT	_	_	_	_	_	_
10	portion	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	whereas	_	SCONJ	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	PMA	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	PIF	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	mainly	_	ADV	_	_	_	_	_	_
25	bound	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	3	_	NUM	_	NumType=Card	_	_	_	_
29	'	_	NOUN	_	_	_	_	_	_
30	portion	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	bound	_	ADJ	_	Degree=Pos	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	Sp	_	NOUN	_	Number=Sing	_	_	_	_
36	binding	_	VERB	_	Number=Sing	_	_	_	_
37	motifs	_	NOUN	_	Number=Plur	_	_	_	_
38	as	_	ADV	_	_	_	_	_	_
39	well	_	ADV	_	Degree=Pos	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	PIF	_	NOUN	_	Number=Sing	_	_	_	_
9	DNA	_	NOUN	_	Number=Sing	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	rapidly	_	ADV	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	de	_	PROPN	_	Number=Sing	_	_	_	_
18	novo	_	PROPN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	sustained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	at	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	high	_	ADJ	_	Degree=Pos	_	_	_	_
28	level	_	NOUN	_	Number=Sing	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	at	_	ADV	_	_	_	_	_	_
31	least	_	ADV	_	Degree=Sup	_	_	_	_
32	23	_	NUM	_	NumType=Card	_	_	_	_
33	h	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	PIF	_	PROPN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	constitutively	_	ADV	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
10	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
11	virus	_	NOUN	_	Number=Sing	_	_	_	_
12	type	_	NOUN	_	Number=Sing	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	MT	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	paper	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	PIF	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	Egr	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	recognition	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	anti-Egr	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	antisera	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	gel	_	NOUN	_	Number=Sing	_	_	_	_
24	mobility	_	NOUN	_	Number=Sing	_	_	_	_
25	shift	_	NOUN	_	Number=Sing	_	_	_	_
26	assays	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	even	_	ADV	_	_	_	_	_	_
29	though	_	SCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2Rbeta	_	PROPN	_	Number=Sing	_	_	_	_
34	DNA	_	PROPN	_	Number=Sing	_	_	_	_
35	binding	_	VERB	_	Number=Sing	_	_	_	_
36	motif	_	NOUN	_	Number=Sing	_	_	_	_
37	differed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	substantially	_	ADV	_	_	_	_	_	_
39	from	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	canonical	_	ADJ	_	Degree=Pos	_	_	_	_
42	Egr	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	binding	_	NOUN	_	Number=Sing	_	_	_	_
46	site	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	Egr	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	bound	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	Sp	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	both	_	CCONJ	_	_	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2Rbeta	_	PROPN	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	HeLaS3	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	transfection	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	Egr	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	could	_	AUX	_	VerbForm=Fin	_	_	_	_
28	drive	_	VERB	_	VerbForm=Inf	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	reporter	_	NOUN	_	Number=Sing	_	_	_	_
33	construct	_	NOUN	_	Number=Sing	_	_	_	_
34	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
35	both	_	DET	_	_	_	_	_	_
36	sites	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Egr	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	could	_	AUX	_	VerbForm=Fin	_	_	_	_
9	form	_	VERB	_	VerbForm=Inf	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	complex	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	correlated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	production	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Egr	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	upon	_	ADP	_	_	_	_	_	_
27	PMA	_	PROPN	_	Number=Sing	_	_	_	_
28	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Egr	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	physically	_	ADV	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	functionally	_	ADV	_	_	_	_	_	_
11	cooperate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2Rbeta	_	PROPN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011947	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Processing	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	precursor	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	HIV	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	protease	_	NOUN	_	Number=Sing	_	_	_	_
16	during	_	ADP	_	_	_	_	_	_
17	acute	_	ADJ	_	Degree=Pos	_	_	_	_
18	infection	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	_	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	genome	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	part	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	latently	_	ADV	_	_	_	_	_	_
30	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	two	_	NUM	_	NumType=Card	_	_	_	_
19	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
20	sites	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	HIV	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	long	_	ADJ	_	Degree=Pos	_	_	_	_
27	terminal	_	NOUN	_	Number=Sing	_	_	_	_
28	repeat	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	consists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	DNA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	subunits	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	relative	_	ADJ	_	Degree=Pos	_	_	_	_
12	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
13	mass	_	ADJ	_	Degree=Pos	_	_	_	_
14	50,000	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	50	_	NUM	_	NumType=Card	_	_	_	_
17	K	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	two	_	NUM	_	NumType=Card	_	_	_	_
22	65	_	NUM	_	NumType=Card	_	_	_	_
23	K	_	NUM	_	Number=Sing	_	_	_	_
24	subunits	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	mature	_	ADJ	_	Degree=Pos	_	_	_	_
9	B	_	ADJ	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	present	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	other	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	types	_	NOUN	_	Number=Plur	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
22	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	External	_	ADJ	_	Degree=Pos	_	_	_	_
2	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	including	_	VERB	_	VerbForm=Ger	_	_	_	_
5	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	result	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	translocation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	active	_	ADJ	_	Degree=Pos	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B.	_	PROPN	_	_	_	_	_	_
21	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	cloning	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	complementary	_	ADJ	_	Degree=Pos	_	_	_	_
26	DNA	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	50K	_	NUM	_	NumType=Card	_	_	_	_
30	subunit	_	NOUN	_	Number=Sing	_	_	_	_
31	helped	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	exclusively	_	ADV	_	_	_	_	_	_
36	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
37	105	_	NUM	_	NumType=Card	_	_	_	_
38	K	_	NUM	_	Number=Sing	_	_	_	_
39	precursor	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	p105	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	V.B.	_	PROPN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	P.K.	_	PROPN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	A.I.	_	PROPN	_	Number=Sing	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	manuscript	_	NOUN	_	Number=Sing	_	_	_	_
51	submitted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	active	_	ADJ	_	Degree=Pos	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	might	_	AUX	_	VerbForm=Fin	_	_	_	_
10	therefore	_	ADV	_	_	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	extent	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	processing	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	p105	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	HIV	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	active	_	ADJ	_	Degree=Pos	_	_	_	_
7	NF	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	effect	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	infection	_	NOUN	_	Number=Sing	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	processing	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	105	_	NUM	_	NumType=Card	_	_	_	_
31	K	_	NUM	_	Number=Sing	_	_	_	_
32	precursor	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	HIV	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	protease	_	NOUN	_	Number=Sing	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	process	_	VERB	_	VerbForm=Inf	_	_	_	_
12	p105	_	NUM	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	active	_	ADJ	_	Degree=Pos	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	NF	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011949	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	specific	_	ADJ	_	Degree=Pos	_	_	_	_
3	differences	_	NOUN	_	Number=Plur	_	_	_	_
4	visualized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	fluorescence	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	situ	_	NOUN	_	Number=Sing	_	_	_	_
9	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
10	pattern	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	interphase	_	NOUN	_	Degree=Pos	_	_	_	_
13	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	different	_	ADJ	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	types	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Application	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	"	_	PUNCT	_	_	_	_	_	_
5	formamide	_	NOUN	_	Number=Sing	_	_	_	_
6	free	_	ADJ	_	Degree=Pos	_	_	_	_
7	"	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	thus	_	ADV	_	_	_	_	_	_
10	"	_	PUNCT	_	_	_	_	_	_
11	material	_	NOUN	_	Number=Sing	_	_	_	_
12	preserving	_	NOUN	_	Number=Sing	_	_	_	_
13	"	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	situ	_	NOUN	_	Number=Sing	_	_	_	_
16	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
17	technique	_	NOUN	_	Number=Sing	_	_	_	_
18	using	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	myf3	_	ADJ	_	Degree=Pos	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	following	_	VERB	_	VerbForm=Ger	_	_	_	_
28	results	_	NOUN	_	Number=Plur	_	_	_	_
29	:	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	rhabdomyosarcoma	_	NOUN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	high	_	ADJ	_	Degree=Pos	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	myf3	_	NOUN	_	Degree=Pos	_	_	_	_
12	show	_	NOUN	_	Number=Sing	_	_	_	_
13	intensive	_	ADJ	_	Degree=Pos	_	_	_	_
14	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
15	signals	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	interphase	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	RNase	_	NOUN	_	Number=Sing	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	prior	_	ADJ	_	Degree=Pos	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
6	considerably	_	ADV	_	_	_	_	_	_
7	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	size	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
12	signals	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	comparison	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	no	_	DET	_	_	_	_	_	_
12	need	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	exists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	show	_	VERB	_	VerbForm=Inf	_	_	_	_
22	barely	_	ADV	_	_	_	_	_	_
23	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
24	signals	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Correspondingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	RNase	_	PROPN	_	Number=Sing	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	no	_	DET	_	_	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
10	pattern	_	NOUN	_	Number=Sing	_	_	_	_
11	at	_	ADV	_	_	_	_	_	_
12	all	_	ADV	_	_	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	efficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
18	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
19	accessibility	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	corresponding	_	VERB	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011953	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Protease	_	NOUN	_	Number=Sing	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	extracts	_	NOUN	_	Number=Plur	_	_	_	_
6	distinguishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	class	_	NOUN	_	Number=Sing	_	_	_	_
9	II	_	NUM	_	NumType=Card	_	_	_	_
10	MHC	_	PROPN	_	Number=Sing	_	_	_	_
11	X1	_	NOUN	_	Number=Sing	_	_	_	_
12	box	_	NOUN	_	Number=Sing	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	wild	_	ADJ	_	Degree=Pos	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	class	_	NOUN	_	Number=Sing	_	_	_	_
23	II	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	X	_	NOUN	_	Number=Sing	_	_	_	_
3	box	_	NOUN	_	Number=Sing	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	critical	_	ADJ	_	Degree=Pos	_	_	_	_
7	for	_	SCONJ	_	_	_	_	_	_
8	directing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	class	_	NOUN	_	Number=Sing	_	_	_	_
13	II	_	NUM	_	NumType=Card	_	_	_	_
14	major	_	ADJ	_	Degree=Pos	_	_	_	_
15	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
16	complex	_	ADJ	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	B	_	ADJ	_	Degree=Pos	_	_	_	_
20	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	several	_	ADJ	_	Degree=Pos	_	_	_	_
3	class	_	NOUN	_	Number=Sing	_	_	_	_
4	II	_	NUM	_	NumType=Card	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	DNA	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	only	_	ADV	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	X	_	NOUN	_	Number=Sing	_	_	_	_
18	box	_	NOUN	_	Number=Sing	_	_	_	_
19	region	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	RFX	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
27	correlation	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	class	_	NOUN	_	Number=Sing	_	_	_	_
30	II	_	NUM	_	NumType=Card	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	being	_	AUX	_	VerbForm=Ger	_	_	_	_
34	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	some	_	DET	_	_	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	lines	_	NOUN	_	Number=Plur	_	_	_	_
40	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	from	_	ADP	_	_	_	_	_	_
42	patients	_	NOUN	_	Number=Sing	_	_	_	_
43	with	_	ADP	_	_	_	_	_	_
44	class	_	NOUN	_	Number=Sing	_	_	_	_
45	II	_	NUM	_	NumType=Card	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
48	congenital	_	ADJ	_	Degree=Pos	_	_	_	_
49	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	evaluate	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	X	_	PROPN	_	Number=Sing	_	_	_	_
8	box	_	NOUN	_	Number=Sing	_	_	_	_
9	DNA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	class	_	NOUN	_	Number=Sing	_	_	_	_
15	II	_	NUM	_	NumType=Card	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	role	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	X	_	NOUN	_	Number=Sing	_	_	_	_
24	box	_	NOUN	_	Number=Sing	_	_	_	_
25	region	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	both	_	DET	_	_	_	_	_	_
30	class	_	NOUN	_	Number=Sing	_	_	_	_
31	II	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	positive	_	ADJ	_	Degree=Pos	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	negative	_	ADJ	_	Degree=Pos	_	_	_	_
37	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	wild	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	Raji	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	two	_	NUM	_	NumType=Card	_	_	_	_
14	class	_	NOUN	_	Number=Sing	_	_	_	_
15	II	_	NUM	_	NumType=Card	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	mutant	_	NOUN	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	SJO	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	RJ2.2.5	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	class	_	NOUN	_	Number=Sing	_	_	_	_
30	II	_	NUM	_	NumType=Card	_	_	_	_
31	negative	_	ADJ	_	Degree=Pos	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	line	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	wild	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	neither	_	DET	_	_	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	class	_	NOUN	_	Number=Sing	_	_	_	_
14	II	_	NUM	_	NumType=Card	_	_	_	_
15	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	lines	_	NOUN	_	Number=Plur	_	_	_	_
18	could	_	AUX	_	VerbForm=Fin	_	_	_	_
19	use	_	VERB	_	VerbForm=Inf	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	X	_	NOUN	_	Number=Sing	_	_	_	_
22	box	_	NOUN	_	Number=Sing	_	_	_	_
23	region	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	direct	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	transiently	_	ADV	_	_	_	_	_	_
31	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	reporter	_	NOUN	_	Number=Sing	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
36	that	_	SCONJ	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	X	_	NOUN	_	Number=Sing	_	_	_	_
39	box	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
42	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
43	pathway	_	NOUN	_	Number=Sing	_	_	_	_
44	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	defective	_	ADJ	_	Degree=Pos	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	X1	_	PROPN	_	Number=Sing	_	_	_	_
7	box	_	NOUN	_	Number=Sing	_	_	_	_
8	DNA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	RFX	_	PROPN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	present	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	wild	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	type	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	mutant	_	NOUN	_	Number=Sing	_	_	_	_
29	RJ2.2.5	_	NOUN	_	Number=Sing	_	_	_	_
30	but	_	CCONJ	_	_	_	_	_	_
31	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
32	absent	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	SJO	_	PROPN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	X1	_	PROPN	_	Number=Sing	_	_	_	_
5	box	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	activities	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	all	_	DET	_	_	_	_	_	_
13	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	lines	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	different	_	ADJ	_	Degree=Pos	_	_	_	_
6	X1	_	NOUN	_	Number=Sing	_	_	_	_
7	box	_	NOUN	_	Number=Sing	_	_	_	_
8	activities	_	NOUN	_	Number=Plur	_	_	_	_
9	represented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	multimeric	_	ADJ	_	Degree=Pos	_	_	_	_
16	forms	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	same	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	s	_	X	_	_	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	protease	_	NOUN	_	Number=Sing	_	_	_	_
26	treatment	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	crude	_	ADJ	_	Degree=Pos	_	_	_	_
30	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
31	extracts	_	NOUN	_	Number=Plur	_	_	_	_
32	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	DNA	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	binding	_	VERB	_	Number=Sing	_	_	_	_
37	assays	_	NOUN	_	Number=Plur	_	_	_	_
38	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
39	carried	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	out	_	ADP	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	that	_	SCONJ	_	_	_	_	_	_
44	B	_	NOUN	_	Number=Sing	_	_	_	_
45	cell	_	NOUN	_	Number=Sing	_	_	_	_
46	extracts	_	NOUN	_	Number=Plur	_	_	_	_
47	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
48	at	_	ADV	_	_	_	_	_	_
49	least	_	ADV	_	Degree=Sup	_	_	_	_
50	two	_	NUM	_	NumType=Card	_	_	_	_
51	X1	_	NUM	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	specific	_	ADJ	_	Degree=Pos	_	_	_	_
54	factors	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	cleaved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	products	_	NOUN	_	Number=Plur	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	band	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	pk	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	RFX	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	similar	_	ADJ	_	Degree=Pos	_	_	_	_
3	comparison	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	protease	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	extracts	_	NOUN	_	Number=Plur	_	_	_	_
9	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	presence	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	band	_	NOUN	_	Number=Sing	_	_	_	_
19	1pk	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	despite	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	absence	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	native	_	ADJ	_	Degree=Pos	_	_	_	_
27	RFX	_	NOUN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	protease	_	NOUN	_	Number=Sing	_	_	_	_
5	treatment	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	analysis	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	SJO	_	PROPN	_	Number=Sing	_	_	_	_
10	extracts	_	NOUN	_	Number=Plur	_	_	_	_
11	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	no	_	DET	_	_	_	_	_	_
13	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	band	_	NOUN	_	Number=Sing	_	_	_	_
18	1pk	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
6	X1	_	NOUN	_	Number=Sing	_	_	_	_
7	box-specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	DNA	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	activities	_	NOUN	_	Number=Plur	_	_	_	_
12	exist	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	all	_	DET	_	_	_	_	_	_
15	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	but	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	presence	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	actively	_	ADV	_	_	_	_	_	_
24	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
25	RFX	_	NOUN	_	Number=Sing	_	_	_	_
26	species	_	NOUN	_	Number=Plur	_	_	_	_
27	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	class	_	NOUN	_	Number=Sing	_	_	_	_
30	II	_	NUM	_	NumType=Card	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011958	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Number=Sing	_	_	_	_
2	RNA	_	PROPN	_	Number=Sing	_	_	_	_
3	display	_	NOUN	_	Number=Sing	_	_	_	_
4	identifies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	novel	_	NOUN	_	Number=Sing	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
11	D	_	PROPN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
3	further	_	VERB	_	Degree=Cmp	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	function	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
9	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
10	D	_	NOUN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	VDR	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	developed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	stable	_	ADJ	_	Degree=Pos	_	_	_	_
20	transfectant	_	ADJ	_	Degree=Pos	_	_	_	_
21	variants	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
25	D	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	line	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	U937	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	which	_	PRON	_	PronType=Rel	_	_	_	_
34	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	either	_	CCONJ	_	_	_	_	_	_
36	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	numbers	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	VDR	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	changes	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	variable	_	ADJ	_	Degree=Pos	_	_	_	_
15	VDR	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Initial	_	ADJ	_	Degree=Pos	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	50	_	NUM	_	NumType=Card	_	_	_	_
7	%	_	SYM	_	Number=Sing	_	_	_	_
8	decrease	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	VDR	_	NOUN	_	Number=Sing	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	fold	_	NOUN	_	Number=Sing	_	_	_	_
19	increase	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	similar	_	ADJ	_	Degree=Pos	_	_	_	_
26	rise	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	c-myc	_	ADJ	_	Number=Sing	_	_	_	_
29	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	carried	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	out	_	ADP	_	_	_	_	_	_
6	using	_	VERB	_	VerbForm=Ger	_	_	_	_
7	differential	_	NOUN	_	Number=Sing	_	_	_	_
8	RNA	_	PROPN	_	Number=Sing	_	_	_	_
9	display	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	DD	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Sequence	_	NOUN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	DD	_	NOUN	_	Number=Sing	_	_	_	_
5	products	_	NOUN	_	Number=Plur	_	_	_	_
6	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	cDNAs	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	identity	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	products	_	NOUN	_	Number=Plur	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	catalytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	sub	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	unit	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	DNA	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	kinase	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	DNA	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	PK	_	PROPN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	CS	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	peroxisomal	_	ADJ	_	Degree=Pos	_	_	_	_
38	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
39	17beta-hydroxysteroid	_	NUM	_	NumType=Card	_	_	_	_
40	dehydrogenase	_	NOUN	_	Number=Sing	_	_	_	_
41	type	_	NOUN	_	Number=Sing	_	_	_	_
42	IV	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	17beta	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	HSD	_	NOUN	_	Number=Sing	_	_	_	_
47	IV	_	NOUN	_	Number=Sing	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	confirmed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	both	_	DET	_	_	_	_	_	_
8	mRNAs	_	PROPN	_	Number=Plur	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	numbers	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	VDR	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Down	_	ADP	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	regulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	17beta-HSD	_	NOUN	_	Number=Sing	_	_	_	_

1	IV	_	NOUN	_	Number=Sing	_	_	_	_
2	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	estradiol	_	NOUN	_	Number=Sing	_	_	_	_
9	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	U937	_	NUM	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	link	_	NOUN	_	Number=Sing	_	_	_	_
17	between	_	ADP	_	_	_	_	_	_
18	estrogenic	_	ADJ	_	Degree=Pos	_	_	_	_
19	pathways	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	Northern	_	ADJ	_	Number=Sing	_	_	_	_
3	analyses	_	NOUN	_	Number=Plur	_	_	_	_
4	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	there	_	PRON	_	_	_	_	_	_
7	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	no	_	DET	_	_	_	_	_	_
9	significant	_	ADJ	_	Degree=Pos	_	_	_	_
10	change	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	17beta	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	HSD	_	NOUN	_	Number=Sing	_	_	_	_
15	IV	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	DNA	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	PK	_	PROPN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	CS	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
24	levels	_	NOUN	_	Number=Plur	_	_	_	_
25	following	_	VERB	_	VerbForm=Ger	_	_	_	_
26	treatment	_	NOUN	_	Number=Sing	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	1,25	_	NUM	_	NumType=Card	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	OH	_	INTJ	_	_	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	2D3	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	although	_	SCONJ	_	_	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	both	_	DET	_	_	_	_	_	_
38	genes	_	NOUN	_	Number=Plur	_	_	_	_
39	varied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	changes	_	NOUN	_	Number=Plur	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	cell	_	NOUN	_	Number=Sing	_	_	_	_
44	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	addition	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	hormone	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	trans	_	NOUN	_	Number=Plur	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	activator	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	VDR	_	PROPN	_	Number=Sing	_	_	_	_
22	may	_	AUX	_	VerbForm=Fin	_	_	_	_
23	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	ligand	_	ADJ	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	independent	_	ADJ	_	Degree=Pos	_	_	_	_
30	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011959	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Mapping	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	repression	_	NOUN	_	Number=Sing	_	_	_	_
6	domain	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	oct	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2A	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	Oct	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2a	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	B	_	ADJ	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	via	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	octamer	_	NOUN	_	Number=Sing	_	_	_	_
22	motif	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Structure	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	function	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	various	_	ADJ	_	Degree=Pos	_	_	_	_
7	Oct	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2a	_	NUM	_	Number=Sing	_	_	_	_
10	effector	_	NOUN	_	Number=Sing	_	_	_	_
11	regions	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	context	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	GAL4	_	PROPN	_	Number=Sing	_	_	_	_
18	DNA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	domain	_	NOUN	_	Number=Sing	_	_	_	_
22	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	Oct	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2a	_	PROPN	_	Number=Sing	_	_	_	_
27	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	two	_	NUM	_	NumType=Card	_	_	_	_
29	functionally	_	ADV	_	_	_	_	_	_
30	different	_	ADJ	_	Degree=Pos	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	domains	_	NOUN	_	Number=Plur	_	_	_	_
33	at	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	N	_	PROPN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	C	_	PROPN	_	Number=Sing	_	_	_	_
39	termini	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	both	_	DET	_	_	_	_	_	_
6	domains	_	NOUN	_	Number=Plur	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	strongly	_	ADV	_	_	_	_	_	_
9	potentiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	interactions	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
14	B	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	coactivators	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	repression	_	NOUN	_	Number=Sing	_	_	_	_
8	domain	_	NOUN	_	Number=Sing	_	_	_	_
9	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	within	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	N	_	PROPN	_	Number=Sing	_	_	_	_
13	terminus	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	Oct	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2a	_	PROPN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	amino	_	PROPN	_	Number=Sing	_	_	_	_
20	acids	_	NOUN	_	Number=Plur	_	_	_	_
21	2-99	_	NUM	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	domain	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	transferred	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	potent	_	NOUN	_	Degree=Pos	_	_	_	_
9	activator	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	strongly	_	ADV	_	_	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	present	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	deletion	_	NOUN	_	Number=Sing	_	_	_	_
8	analysis	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	N-terminal	_	ADJ	_	Number=Sing	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	Oct	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2a	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
21	repression	_	NOUN	_	Number=Sing	_	_	_	_
22	domain	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	stretch	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	23	_	NUM	_	NumType=Card	_	_	_	_
7	amino	_	ADJ	_	Degree=Pos	_	_	_	_
8	acids	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	rich	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	serine	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	threonine	_	NOUN	_	Number=Sing	_	_	_	_
15	residues	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	most	_	ADJ	_	Degree=Sup	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	repression	_	NOUN	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	repression	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	strongly	_	ADV	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
13	present	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	reporter	_	NOUN	_	Number=Sing	_	_	_	_
17	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
18	as	_	ADV	_	_	_	_	_	_
19	well	_	ADV	_	Degree=Pos	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	line	_	NOUN	_	Number=Sing	_	_	_	_
25	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	possibility	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	Oct	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2a	_	PROPN	_	Number=Sing	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	act	_	VERB	_	VerbForm=Inf	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	activator	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	repressor	_	NOUN	_	Number=Sing	_	_	_	_
17	may	_	AUX	_	VerbForm=Fin	_	_	_	_
18	have	_	VERB	_	VerbForm=Inf	_	_	_	_
19	important	_	ADJ	_	Degree=Pos	_	_	_	_
20	consequences	_	NOUN	_	Number=Plur	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	function	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	Oct	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2a	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	B	_	ADJ	_	Degree=Pos	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	other	_	ADJ	_	Degree=Pos	_	_	_	_
34	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
35	processes	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011964	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	tumour	_	NOUN	_	Number=Sing	_	_	_	_
3	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	surface	_	NOUN	_	Number=Sing	_	_	_	_
6	antigen	_	NOUN	_	Number=Sing	_	_	_	_
7	A6H	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	CD4	_	NOUN	_	Number=Sing	_	_	_	_
13	+	_	SYM	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	CD8	_	NOUN	_	Number=Sing	_	_	_	_
17	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	A6H	_	NOUN	_	Number=Sing	_	_	_	_
3	monoclonal	_	ADJ	_	Number=Sing	_	_	_	_
4	antibody	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	mAb	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	120,000-140,000	_	NUM	_	NumType=Card	_	_	_	_
11	MW	_	PROPN	_	Number=Sing	_	_	_	_
12	antigen	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	similar	_	ADJ	_	Degree=Pos	_	_	_	_
18	densities	_	NOUN	_	Number=Plur	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	85	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	SYM	_	_	_	_	_	_
22	90	_	NUM	_	NumType=Card	_	_	_	_
23	%	_	SYM	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	CD4	_	NOUN	_	Number=Sing	_	_	_	_
27	+	_	SYM	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	CD8	_	NOUN	_	Number=Sing	_	_	_	_
30	+	_	SYM	_	_	_	_	_	_

1	T	_	X	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	renal	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	carcinomas	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	A6H	_	PROPN	_	Number=Sing	_	_	_	_
6	mAb	_	NOUN	_	Number=Sing	_	_	_	_
7	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	report	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	A6H	_	PROPN	_	Number=Sing	_	_	_	_
10	costimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
15	production	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	CD4	_	NOUN	_	Number=Sing	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	Unexpectedly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CD8	_	NOUN	_	Number=Sing	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_

1	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
2	subpopulation	_	NOUN	_	Number=Sing	_	_	_	_
3	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	CD4	_	PROPN	_	Number=Sing	_	_	_	_
2	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	costimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	A6H	_	PROPN	_	Number=Sing	_	_	_	_
7	mAb	_	NOUN	_	Number=Sing	_	_	_	_
8	upregulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	CD80	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	CD86	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	CD71	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	R	_	PROPN	_	Number=Sing	_	_	_	_
24	alpha	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2R	_	PROPN	_	Number=Sing	_	_	_	_
29	beta	_	PROPN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2R	_	NUM	_	Number=Sing	_	_	_	_
34	gamma	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	while	_	SCONJ	_	_	_	_	_	_
37	no	_	DET	_	_	_	_	_	_
38	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
39	up	_	ADP	_	_	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	regulation	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
44	cell	_	NOUN	_	Number=Sing	_	_	_	_
45	surface	_	NOUN	_	Number=Sing	_	_	_	_
46	molecules	_	NOUN	_	Number=Plur	_	_	_	_
47	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
48	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	CD8	_	NOUN	_	Number=Sing	_	_	_	_
51	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	nature	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	A6H	_	PROPN	_	Number=Sing	_	_	_	_
10	mAb	_	NOUN	_	Number=Sing	_	_	_	_
11	costimulus	_	NOUN	_	Number=Sing	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	OCT	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	AP	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappa	_	NOUN	_	Number=Sing	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	which	_	PRON	_	PronType=Rel	_	_	_	_
37	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	to	_	PART	_	_	_	_	_	_
40	be	_	AUX	_	VerbForm=Inf	_	_	_	_
41	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
42	regulators	_	NOUN	_	Number=Plur	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	several	_	ADJ	_	Degree=Pos	_	_	_	_
45	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
48	receptor	_	NOUN	_	Number=Sing	_	_	_	_
49	genes	_	NOUN	_	Number=Plur	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	including	_	VERB	_	VerbForm=Ger	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	IL	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	2	_	NUM	_	NumType=Card	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	IL	_	PROPN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	2R	_	NUM	_	Number=Sing	_	_	_	_
60	genes	_	NOUN	_	Number=Plur	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	Co	_	X	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	ligation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	A6H	_	PROPN	_	Number=Sing	_	_	_	_
7	antigen	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	CD3	_	PROPN	_	Number=Sing	_	_	_	_
11	complex	_	NOUN	_	Number=Sing	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	CD4	_	PROPN	_	Number=Sing	_	_	_	_
23	+	_	SYM	_	_	_	_	_	_

1	T	_	X	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	whereas	_	SCONJ	_	_	_	_	_	_
5	no	_	DET	_	_	_	_	_	_
6	increase	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	octamer	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	Oct	_	X	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	T	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
29	alone	_	ADV	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	AP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	A6H	_	NOUN	_	Number=Sing	_	_	_	_
13	costimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	CD8	_	NOUN	_	Number=Sing	_	_	_	_
15	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	both	_	DET	_	_	_	_	_	_
6	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
7	steps	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	CD8	_	PROPN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_

1	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	as	_	ADV	_	_	_	_	_	_
4	well	_	ADV	_	Degree=Pos	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	later	_	ADJ	_	Degree=Cmp	_	_	_	_
8	phases	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	unresponsive	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	A6H	_	NOUN	_	Number=Sing	_	_	_	_
13	ligation	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	differences	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	A6H	_	NOUN	_	Number=Sing	_	_	_	_
6	molecule	_	NOUN	_	Number=Sing	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
9	regulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	A6H	_	NOUN	_	Number=Sing	_	_	_	_
13	transduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	pathway	_	NOUN	_	Number=Sing	_	_	_	_
19	may	_	AUX	_	VerbForm=Fin	_	_	_	_
20	exist	_	VERB	_	VerbForm=Inf	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	CD4	_	PROPN	_	Number=Sing	_	_	_	_
23	+	_	SYM	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	CD8	_	PROPN	_	Number=Sing	_	_	_	_
26	+	_	SYM	_	_	_	_	_	_

1	T	_	NUM	_	NumType=Card	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	subpopulations	_	NOUN	_	Number=Plur	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011965	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	chain	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	:	_	PUNCT	_	_	_	_	_	_
18	potential	_	ADJ	_	Degree=Pos	_	_	_	_
19	role	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	physical	_	ADJ	_	Degree=Pos	_	_	_	_
22	interactions	_	NOUN	_	Number=Plur	_	_	_	_
23	between	_	ADP	_	_	_	_	_	_
24	Elf	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	HMG	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	Y	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappa	_	PROPN	_	Number=Sing	_	_	_	_
39	B	_	PROPN	_	Number=Sing	_	_	_	_
40	family	_	NOUN	_	Number=Sing	_	_	_	_
41	proteins	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	alpha-chain	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2R	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	rapidly	_	ADV	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	potently	_	ADV	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
25	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Previously	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
5	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	299	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	228	_	NUM	_	NumType=Card	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	PROPN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	CArG	_	PROPN	_	Number=Sing	_	_	_	_
21	motifs	_	NOUN	_	Number=Plur	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	characterization	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
9	essential	_	ADJ	_	Degree=Pos	_	_	_	_
10	positive	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	between	_	ADP	_	_	_	_	_	_
15	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	137	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	-	_	SYM	_	_	_	_	_	_
20	64	_	NUM	_	NumType=Card	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	Elf	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	HMG	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	Y	_	NOUN	_	_	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	element	_	NOUN	_	Number=Sing	_	_	_	_
3	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	paralleling	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	specificity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	Elf	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2R	_	NOUN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	when	_	ADV	_	PronType=Int	_	_	_	_
12	either	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	Elf	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	HMG	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	Y	_	X	_	_	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	site	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	mutated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Coexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	both	_	DET	_	_	_	_	_	_
4	proteins	_	NOUN	_	Number=Plur	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	137	_	NUM	_	NumType=Card	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	-	_	SYM	_	_	_	_	_	_
13	64	_	NUM	_	NumType=Card	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	COS	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	7	_	NUM	_	NumType=Card	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Elf	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	physically	_	ADV	_	_	_	_	_	_
5	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	HMG	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	p50	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	c	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	Rel	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	vitro	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	interactions	_	NOUN	_	Number=Plur	_	_	_	_
30	might	_	AUX	_	VerbForm=Fin	_	_	_	_
31	functionally	_	ADV	_	_	_	_	_	_
32	coordinate	_	VERB	_	VerbForm=Inf	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	actions	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	upstream	_	ADJ	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
40	positive	_	ADJ	_	Degree=Pos	_	_	_	_
41	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
42	elements	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
5	report	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	physical	_	ADJ	_	Degree=Pos	_	_	_	_
9	interaction	_	NOUN	_	Number=Sing	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	Ets	_	NOUN	_	Number=Sing	_	_	_	_
13	family	_	NOUN	_	Number=Sing	_	_	_	_
14	member	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	PROPN	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	family	_	NOUN	_	Number=Sing	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	significant	_	ADJ	_	Degree=Pos	_	_	_	_
5	new	_	ADJ	_	Degree=Pos	_	_	_	_
6	insights	_	NOUN	_	Number=Plur	_	_	_	_
7	into	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	DNA	_	NOUN	_	Number=Sing	_	_	_	_
16	interactions	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	type	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2R	_	NUM	_	Number=Sing	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	also	_	ADV	_	_	_	_	_	_
34	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	implications	_	NOUN	_	Number=Plur	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	other	_	ADJ	_	Degree=Pos	_	_	_	_
38	genes	_	NOUN	_	Number=Plur	_	_	_	_
39	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	Elf	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	1	_	NUM	_	NumType=Card	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	NF	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	kappa	_	PROPN	_	Number=Sing	_	_	_	_
48	B	_	PROPN	_	Number=Sing	_	_	_	_
49	family	_	NOUN	_	Number=Sing	_	_	_	_
50	proteins	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011968	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	LMP	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	SCONJ	_	_	_	_	_	_
10	targeting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
13	molecule	_	NOUN	_	Number=Sing	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	kappa	_	VERB	_	Number=Sing	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	alpha	_	PROPN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	LMP	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	Barr	_	PROPN	_	Number=Sing	_	_	_	_
9	virus	_	NOUN	_	Number=Sing	_	_	_	_
10	membrane	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	during	_	ADP	_	_	_	_	_	_
14	latent	_	ADJ	_	Degree=Pos	_	_	_	_
15	infection	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	oncogenic	_	ADJ	_	Degree=Pos	_	_	_	_
19	properties	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	as	_	SCONJ	_	_	_	_	_	_
22	judged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	ability	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	transform	_	VERB	_	VerbForm=Inf	_	_	_	_
28	B	_	ADJ	_	Degree=Pos	_	_	_	_
29	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	rodent	_	ADJ	_	Degree=Pos	_	_	_	_
32	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	LMP	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	bcl2	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	protects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	as	_	ADV	_	_	_	_	_	_
19	well	_	ADV	_	Degree=Pos	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
24	other	_	ADJ	_	Degree=Pos	_	_	_	_
25	proteins	_	NOUN	_	Number=Plur	_	_	_	_
26	involved	_	ADJ	_	Degree=Pos	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	cell	_	VERB	_	Number=Sing	_	_	_	_
29	regulation	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	growth	_	NOUN	_	Number=Sing	_	_	_	_
32	control	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	LMP	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	upregulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	plausible	_	ADJ	_	Degree=Pos	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	LMP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	modifies	_	VERB	_	Number=Plur	_	_	_	_
23	signal	_	NOUN	_	Number=Sing	_	_	_	_
24	transduction	_	NOUN	_	Number=Sing	_	_	_	_
25	pathways	_	NOUN	_	Number=Plur	_	_	_	_
26	that	_	DET	_	PronType=Rel	_	_	_	_
27	result	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	one	_	NUM	_	NumType=Card	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	more	_	ADJ	_	Degree=Cmp	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	factors	_	NOUN	_	Number=Plur	_	_	_	_
37	that	_	PRON	_	PronType=Rel	_	_	_	_
38	ultimately	_	ADV	_	_	_	_	_	_
39	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	transcription	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	oncogenic	_	ADJ	_	Degree=Pos	_	_	_	_
43	genes	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	involved	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	growth	_	NOUN	_	Number=Sing	_	_	_	_
20	control	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	be	_	AUX	_	VerbForm=Inf	_	_	_	_
27	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	LMP	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	s	_	X	_	_	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	DNA	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	functional	_	ADJ	_	Degree=Pos	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	present	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	B	_	ADJ	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	stably	_	ADV	_	_	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	transiently	_	ADV	_	_	_	_	_	_
25	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	LMP	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
2	kappa	_	VERB	_	Number=Sing	_	_	_	_
3	B	_	PROPN	_	Number=Sing	_	_	_	_
4	alpha	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	selectively	_	ADV	_	_	_	_	_	_
7	modified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	LMP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	phosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
3	form	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	kappa	_	VERB	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	turnover	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	degradation	_	NOUN	_	Number=Sing	_	_	_	_
15	correlate	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	NF	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	translocation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	including	_	VERB	_	VerbForm=Ger	_	_	_	_
17	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
18	encoding	_	NOUN	_	Number=Sing	_	_	_	_
19	p105	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	kappa	_	VERB	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	MAD3	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	LMP	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	B	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	lines	_	NOUN	_	Number=Plur	_	_	_	_
18	by	_	SCONJ	_	_	_	_	_	_
19	targeting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	kappa	_	VERB	_	Number=Sing	_	_	_	_
22	B	_	PROPN	_	Number=Sing	_	_	_	_
23	alpha	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	pathways	_	NOUN	_	Number=Plur	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	LMP	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	result	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	posttranslational	_	ADJ	_	Degree=Pos	_	_	_	_
14	modifications	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	kappa	_	PROPN	_	Number=Sing	_	_	_	_
18	B	_	PROPN	_	Number=Sing	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	will	_	AUX	_	VerbForm=Fin	_	_	_	_
21	aid	_	VERB	_	VerbForm=Inf	_	_	_	_
22	in	_	SCONJ	_	_	_	_	_	_
23	determining	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	role	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	virus	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	host	_	NOUN	_	Number=Sing	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	protein	_	NOUN	_	Number=Sing	_	_	_	_
33	interaction	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	Barr	_	PROPN	_	Number=Sing	_	_	_	_
38	virus	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	oncogenesis	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011975	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
2	colony	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	72	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kDa	_	NOUN	_	Number=Sing	_	_	_	_
11	isoform	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	STAT3	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
2	colony	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	G	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	CSF	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	signaling	_	NOUN	_	Number=Sing	_	_	_	_
12	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	STATs	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	serve	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	dual	_	ADJ	_	Degree=Pos	_	_	_	_
22	function	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	signal	_	NOUN	_	Number=Sing	_	_	_	_
25	transduction	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	G-CSF	_	PROPN	_	Number=Sing	_	_	_	_
6	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
9	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	like	_	ADP	_	Degree=Pos	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	immature	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	mature	_	ADJ	_	Degree=Pos	_	_	_	_
17	normal	_	ADJ	_	Degree=Pos	_	_	_	_
18	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	StatG	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	StatG	_	VERB	_	Number=Sing	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	normal	_	ADJ	_	Degree=Pos	_	_	_	_
4	immature	_	ADJ	_	Degree=Pos	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	i.e.	_	X	_	_	_	_	_	_
10	adult	_	NOUN	_	Number=Sing	_	_	_	_
11	CD34	_	NOUN	_	Number=Sing	_	_	_	_
12	+	_	SYM	_	_	_	_	_	_
13	bone	_	NOUN	_	NumType=Card	_	_	_	_
14	marrow	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Stat3beta	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	investigation	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	undertaken	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	composition	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	StatG	_	PROPN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	mature	_	ADJ	_	Degree=Pos	_	_	_	_
13	normal	_	ADJ	_	Degree=Pos	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	i.e.	_	X	_	_	_	_	_	_
19	polymorphonuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	neutrophilic	_	ADJ	_	Degree=Pos	_	_	_	_
21	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	PMN	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	major	_	ADJ	_	Degree=Pos	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	extracts	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	PMN	_	PROPN	_	Number=Sing	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	G	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	CSF	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	high	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	affinity	_	NOUN	_	Number=Sing	_	_	_	_
23	serum	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
26	element	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	hSIE	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	72	_	NUM	_	NumType=Card	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kDa	_	NOUN	_	Number=Sing	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	that	_	PRON	_	PronType=Rel	_	_	_	_
37	cross	_	VERB	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	reacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
42	monoclonal	_	ADJ	_	Number=Sing	_	_	_	_
43	antibody	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	which	_	PRON	_	PronType=Rel	_	_	_	_
46	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
47	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
48	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	Stat3gamma	_	PROPN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Stat3gamma	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	derived	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	Stat3alpha	_	PROPN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	limited	_	ADJ	_	Degree=Pos	_	_	_	_
8	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	lacks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	carboxyl	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
15	portion	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	Stat3alpha	_	PROPN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Stat3alpha	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	involved	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
13	findings	_	NOUN	_	Number=Plur	_	_	_	_
14	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	possibility	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	Stat3gamma	_	PROPN	_	Number=Sing	_	_	_	_
19	may	_	AUX	_	VerbForm=Fin	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	transcriptionally	_	ADV	_	_	_	_	_	_
22	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	may	_	AUX	_	VerbForm=Fin	_	_	_	_
25	compete	_	VERB	_	VerbForm=Inf	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	Stat3alpha	_	PROPN	_	Number=Sing	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	sites	_	NOUN	_	Number=Plur	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
34	terminally	_	ADV	_	_	_	_	_	_
35	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
36	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011978	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	independent	_	ADJ	_	Degree=Pos	_	_	_	_
7	suppression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	ascorbic	_	ADJ	_	Degree=Pos	_	_	_	_
13	acid	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Ascorbic	_	ADJ	_	Number=Sing	_	_	_	_
2	acid	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	ascorbate	_	NOUN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	vitamin	_	VERB	_	Number=Sing	_	_	_	_
7	C	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	latently	_	ADV	_	_	_	_	_	_
20	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	T	_	ADJ	_	Number=Sing	_	_	_	_
22	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	following	_	VERB	_	VerbForm=Ger	_	_	_	_
25	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	tumor	_	NOUN	_	Number=Sing	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	PMA	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
35	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	TNF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	alpha	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	assess	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	via	_	ADP	_	_	_	_	_	_
9	modulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	PROPN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
22	carried	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	out	_	ADP	_	_	_	_	_	_
24	gel	_	NOUN	_	Number=Sing	_	_	_	_
25	shift	_	NOUN	_	Number=Sing	_	_	_	_
26	analysis	_	NOUN	_	Number=Sing	_	_	_	_
27	on	_	ADP	_	_	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	extracts	_	NOUN	_	Number=Plur	_	_	_	_
30	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	under	_	ADP	_	_	_	_	_	_
32	different	_	ADJ	_	Degree=Pos	_	_	_	_
33	conditions	_	NOUN	_	Number=Plur	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	presence	_	NOUN	_	Number=Sing	_	_	_	_
40	or	_	CCONJ	_	_	_	_	_	_
41	absence	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	ascorbate	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	N	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	acetylcysteine	_	NOUN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	NAC	_	PROPN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	or	_	CCONJ	_	_	_	_	_	_
53	zidovudine	_	NOUN	_	Number=Sing	_	_	_	_
54	(	_	PUNCT	_	_	_	_	_	_
55	AZT	_	PROPN	_	Number=Sing	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	ACH	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	T	_	NUM	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	NAC	_	PROPN	_	Number=Sing	_	_	_	_
10	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	PMA	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	hydrogen	_	NOUN	_	Degree=Pos	_	_	_	_
22	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	strong	_	ADJ	_	Degree=Pos	_	_	_	_
29	suppression	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	activation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	neither	_	CCONJ	_	_	_	_	_	_
5	ascorbate	_	NOUN	_	Number=Sing	_	_	_	_
6	nor	_	CCONJ	_	_	_	_	_	_
7	AZT	_	PROPN	_	Number=Sing	_	_	_	_
8	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	under	_	ADP	_	_	_	_	_	_
15	all	_	DET	_	_	_	_	_	_
16	three	_	NUM	_	NumType=Card	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	conditions	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	ACH	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	line	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Ascorbate	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	AZT	_	PROPN	_	Number=Sing	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	no	_	DET	_	_	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	following	_	VERB	_	VerbForm=Ger	_	_	_	_
15	TNF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	PMA	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	U1	_	PROPN	_	Number=Sing	_	_	_	_
26	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
7	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	ascorbate	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	via	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	unlike	_	SCONJ	_	_	_	_	_	_
24	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
25	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	other	_	ADJ	_	Degree=Pos	_	_	_	_
28	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011989	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	naive	_	ADJ	_	Degree=Pos	_	_	_	_
5	T-helper	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	Th	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	into	_	ADP	_	_	_	_	_	_
11	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	secreting	_	VERB	_	Number=Sing	_	_	_	_
14	effector	_	NOUN	_	Number=Sing	_	_	_	_

1	Th	_	DET	_	_	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	exposure	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
7	signals	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	including	_	VERB	_	VerbForm=Ger	_	_	_	_
10	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
11	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-4	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	4	_	X	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	major	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	process	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	SCONJ	_	_	_	_	_	_
15	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	secreting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	Th2	_	DET	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	tightly	_	ADV	_	_	_	_	_	_
12	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	level	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	coordinated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factors	_	NOUN	_	Number=Plur	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	elements	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
32	promoter	_	NOUN	_	Number=Sing	_	_	_	_
33	region	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	family	_	NOUN	_	Number=Sing	_	_	_	_
11	members	_	NOUN	_	Number=Plur	_	_	_	_
12	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	critical	_	ADJ	_	Degree=Pos	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	SCONJ	_	_	_	_	_	_
17	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	4	_	NUM	_	NumType=Card	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	interact	_	NOUN	_	Number=Sing	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	up	_	ADP	_	_	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	five	_	NUM	_	NumType=Card	_	_	_	_
28	sequences	_	NOUN	_	Number=Plur	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	P0	_	NOUN	_	Number=Sing	_	_	_	_
32	through	_	ADP	_	_	_	_	_	_
33	P4	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	4	_	NUM	_	NumType=Card	_	_	_	_
40	promoter	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	induces	_	NOUN	_	Number=Plur	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	although	_	SCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	4	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	signal	_	NOUN	_	Number=Sing	_	_	_	_
31	transducer	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	activator	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	6	_	NUM	_	NumType=Card	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
42	for	_	ADP	_	_	_	_	_	_
43	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
44	effect	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
6	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	three	_	NUM	_	NumType=Card	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	sites	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
20	mobility	_	NOUN	_	Number=Sing	_	_	_	_
21	shift	_	NOUN	_	Number=Sing	_	_	_	_
22	assays	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	sites	_	NOUN	_	Number=Plur	_	_	_	_
3	overlap	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	P1	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	P2	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	P4	_	NOUN	_	Number=Sing	_	_	_	_
11	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
12	elements	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
7	in	_	SCONJ	_	_	_	_	_	_
8	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
19	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	different	_	ADJ	_	Degree=Pos	_	_	_	_
24	intact	_	NOUN	_	Degree=Pos	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	4	_	NUM	_	NumType=Card	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	constructs	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
32	assays	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	whereas	_	SCONJ	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	multimerized	_	ADJ	_	Degree=Pos	_	_	_	_
8	response	_	NOUN	_	Number=Sing	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	germline	_	NOUN	_	Number=Sing	_	_	_	_
13	IgE	_	PROPN	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	highly	_	ADV	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	intact	_	ADJ	_	Number=Sing	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	4	_	NUM	_	NumType=Card	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
37	repressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	under	_	ADP	_	_	_	_	_	_
39	similar	_	ADJ	_	Degree=Pos	_	_	_	_
40	conditions	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	function	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Stat6	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	highly	_	ADV	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	promoter	_	NOUN	_	VerbForm=Ger	_	_	_	_
13	context	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	indirect	_	ADJ	_	Degree=Pos	_	_	_	_
27	manner	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030011993	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Paradoxical	_	ADJ	_	Degree=Pos	_	_	_	_
2	priming	_	NOUN	_	Number=Sing	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	10	_	NUM	_	NumType=Card	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	production	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	well	_	ADV	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	known	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
9	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	vitro	_	ADP	_	Number=Sing	_	_	_	_
7	experimental	_	ADJ	_	Degree=Pos	_	_	_	_
8	studies	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	10	_	NUM	_	NumType=Card	_	_	_	_
14	primed	_	ADJ	_	Degree=Pos	_	_	_	_
15	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	production	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	tumor	_	NOUN	_	Number=Sing	_	_	_	_
24	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	TNF	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	upon	_	ADP	_	_	_	_	_	_
30	further	_	ADJ	_	Degree=Pos	_	_	_	_
31	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	LPS	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Monocytes	_	NOUN	_	Number=Plur	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
4	blood	_	NOUN	_	Number=Sing	_	_	_	_
5	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	whole	_	ADJ	_	Degree=Pos	_	_	_	_
13	blood	_	NOUN	_	Number=Sing	_	_	_	_
14	maintained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	20	_	NUM	_	NumType=Card	_	_	_	_
17	h	_	NOUN	_	Number=Sing	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	37	_	NUM	_	NumType=Card	_	_	_	_
20	degrees	_	NOUN	_	Number=Plur	_	_	_	_
21	C	_	PROPN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	presence	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	10	_	NUM	_	NumType=Card	_	_	_	_
31	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	capacity	_	NOUN	_	Number=Sing	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
37	TNF	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	response	_	NOUN	_	Number=Sing	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	LPS	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	LPS	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	6	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	spontaneous	_	ADJ	_	Degree=Pos	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1ra	_	PROPN	_	Number=Sing	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	first	_	ADV	_	_	_	_	_	_
6	cultured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	20	_	NUM	_	NumType=Card	_	_	_	_
9	h	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	presence	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	10	_	NUM	_	NumType=Card	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	Teflon	_	PROPN	_	Number=Sing	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
21	adherence	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	washed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	remove	_	VERB	_	VerbForm=Inf	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	10	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	then	_	ADV	_	PronType=Dem	_	_	_	_
31	further	_	ADV	_	Degree=Pos	_	_	_	_
32	cultured	_	VERB	_	Degree=Pos	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	plastic	_	ADJ	_	Degree=Pos	_	_	_	_
35	dishes	_	NOUN	_	Number=Plur	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	additional	_	ADJ	_	Degree=Pos	_	_	_	_
39	20	_	NUM	_	NumType=Card	_	_	_	_
40	h	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	presence	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	LPS	_	PROPN	_	Number=Sing	_	_	_	_
46	or	_	CCONJ	_	_	_	_	_	_
47	IL	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	1beta	_	PROPN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
52	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
53	release	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	TNF	_	PROPN	_	Number=Sing	_	_	_	_
56	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
57	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	case	_	NOUN	_	Number=Sing	_	_	_	_
6	when	_	ADV	_	PronType=Int	_	_	_	_
7	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	pre-cultured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	plastic	_	ADJ	_	Degree=Pos	_	_	_	_
12	multidishes	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	presence	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	10	_	NUM	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	LPS	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	when	_	ADV	_	PronType=Int	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	pre-treatment	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	10	_	NUM	_	NumType=Card	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	plastic	_	ADJ	_	Degree=Pos	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	whereas	_	SCONJ	_	_	_	_	_	_
24	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	case	_	NOUN	_	Number=Sing	_	_	_	_
29	when	_	ADV	_	PronType=Int	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	pre-cultured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	10	_	NUM	_	NumType=Card	_	_	_	_
37	on	_	ADP	_	_	_	_	_	_
38	Teflon	_	PROPN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	NFkappaB	_	ADJ	_	Number=Sing	_	_	_	_
4	translocation	_	NOUN	_	Number=Sing	_	_	_	_
5	following	_	VERB	_	VerbForm=Ger	_	_	_	_
6	LPS	_	PROPN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
10	after	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	10	_	NUM	_	NumType=Card	_	_	_	_
14	pre-treatment	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	Teflon	_	PROPN	_	Number=Sing	_	_	_	_
17	than	_	ADP	_	_	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	plastic	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	frequency	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CD16	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	CD68	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	+	_	SYM	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	among	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	CD14	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	+	_	SYM	_	_	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	presence	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	10	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	independently	_	ADV	_	_	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	pre-culture	_	ADJ	_	Degree=Pos	_	_	_	_
35	conditions	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Altogether	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	up	_	ADP	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
18	production	_	NOUN	_	Number=Sing	_	_	_	_
19	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	prevention	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
25	adherence	_	NOUN	_	Number=Sing	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	red	_	ADJ	_	Degree=Pos	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	whole	_	ADJ	_	Degree=Pos	_	_	_	_
32	blood	_	NOUN	_	Number=Sing	_	_	_	_
33	assays	_	NOUN	_	Number=Plur	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	cultures	_	NOUN	_	Number=Plur	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
39	on	_	ADP	_	_	_	_	_	_
40	Teflon	_	PROPN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	adherence	_	NOUN	_	Number=Sing	_	_	_	_
6	parameter	_	NOUN	_	Number=Sing	_	_	_	_
7	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	no	_	DET	_	_	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	10	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	modulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	some	_	DET	_	_	_	_	_	_
20	monocyte	_	ADJ	_	Degree=Pos	_	_	_	_
21	surface	_	NOUN	_	Number=Sing	_	_	_	_
22	markers	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012016	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Sequence	_	NOUN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	cultured	_	VERB	_	Degree=Pos	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	FOSB	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	G0S3	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	G0S3	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	member	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	set	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	putative	_	ADJ	_	Degree=Pos	_	_	_	_
10	G0	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	G1	_	NOUN	_	Number=Sing	_	_	_	_
13	switch	_	NOUN	_	Number=Sing	_	_	_	_
14	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	G0S	_	NOUN	_	Number=Sing	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	SCONJ	_	_	_	_	_	_
22	screening	_	VERB	_	VerbForm=Ger	_	_	_	_
23	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
24	libraries	_	NOUN	_	Number=Plur	_	_	_	_
25	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	blood	_	NOUN	_	Number=Sing	_	_	_	_
29	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	hr	_	NOUN	_	Number=Sing	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	lectin	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	high	_	ADJ	_	Degree=Pos	_	_	_	_
5	homology	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	murine	_	NOUN	_	Number=Sing	_	_	_	_
9	FOSB	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	component	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	AP1	_	NOUN	_	Number=Sing	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	regulator	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Comparison	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
6	sequences	_	NOUN	_	Number=Plur	_	_	_	_
7	reveals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	4	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	exon	_	NOUN	_	Number=Sing	_	_	_	_
12	structure	_	NOUN	_	Number=Sing	_	_	_	_
13	characteristic	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	FOS	_	PROPN	_	Number=Sing	_	_	_	_
17	family	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Freshly	_	ADV	_	_	_	_	_	_
2	isolated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	high	_	ADJ	_	Degree=Pos	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	FOSB	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	G0S3	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	FOS	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	G0S7	_	NOUN	_	Number=Sing	_	_	_	_
15	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	decline	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	rapidly	_	ADV	_	_	_	_	_	_
20	during	_	ADP	_	_	_	_	_	_
21	incubation	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	culture	_	NOUN	_	Number=Sing	_	_	_	_
24	medium	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	high	_	ADJ	_	Degree=Pos	_	_	_	_
9	initial	_	ADJ	_	Degree=Pos	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	caused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	isolation	_	NOUN	_	Number=Sing	_	_	_	_
16	procedure	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	reflect	_	VERB	_	VerbForm=Inf	_	_	_	_
22	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	preincubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	day	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	FOS	_	NOUN	_	Number=Sing	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	reach	_	VERB	_	VerbForm=Inf	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	maximum	_	ADJ	_	Degree=Pos	_	_	_	_
15	20	_	NUM	_	NumType=Card	_	_	_	_
16	min	_	NOUN	_	Number=Plur	_	_	_	_
17	after	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	addition	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	lectin	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	decline	_	VERB	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	control	_	VERB	_	Number=Sing	_	_	_	_
26	levels	_	NOUN	_	Number=Plur	_	_	_	_
27	over	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	next	_	ADJ	_	Degree=Pos	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	hr	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Levels	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	FOSB	_	NOUN	_	Number=Sing	_	_	_	_
4	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
5	reach	_	VERB	_	Number=Sing	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	maximum	_	ADJ	_	Degree=Pos	_	_	_	_
8	40	_	NUM	_	NumType=Card	_	_	_	_
9	min	_	NOUN	_	Number=Plur	_	_	_	_
10	after	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	addition	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	lectin	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	decline	_	VERB	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	control	_	VERB	_	Number=Sing	_	_	_	_
19	levels	_	NOUN	_	Number=Plur	_	_	_	_
20	over	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	next	_	ADJ	_	Degree=Pos	_	_	_	_
23	6	_	NUM	_	NumType=Card	_	_	_	_
24	hr	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	freshly	_	ADV	_	_	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	FOS	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	FOSB	_	NOUN	_	Number=Sing	_	_	_	_
10	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
11	increase	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	dramatically	_	ADV	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
19	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
20	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	preincubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	cycloheximide	_	ADJ	_	Degree=Pos	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	especially	_	ADV	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	case	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	FOSB	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	differences	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	FOS	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	FOSB	_	NOUN	_	Number=Sing	_	_	_	_
9	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	different	_	ADJ	_	Degree=Pos	_	_	_	_
11	roles	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	regulation	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Regions	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	low	_	ADJ	_	Degree=Pos	_	_	_	_
4	base	_	NOUN	_	Number=Sing	_	_	_	_
5	order	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	stem	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	loop	_	NOUN	_	Number=Sing	_	_	_	_
11	potential	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	region	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	where	_	ADV	_	PronType=Int	_	_	_	_
4	base	_	NOUN	_	Number=Sing	_	_	_	_
5	order	_	NOUN	_	Number=Sing	_	_	_	_
6	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	adapted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	purposes	_	NOUN	_	Number=Plur	_	_	_	_
11	other	_	ADJ	_	Degree=Pos	_	_	_	_
12	than	_	ADP	_	_	_	_	_	_
13	stem	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	loop	_	NOUN	_	Number=Sing	_	_	_	_
16	stability	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	e.g.	_	X	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	gene	_	VERB	_	Number=Sing	_	_	_	_
24	regulation	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Regions	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	low	_	ADJ	_	Degree=Pos	_	_	_	_
4	potential	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	68.5	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kb	_	NOUN	_	Number=Sing	_	_	_	_
10	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
11	segment	_	NOUN	_	Number=Sing	_	_	_	_
12	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	FOSB	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	potential	_	NOUN	_	Number=Sing	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	help	_	VERB	_	VerbForm=Inf	_	_	_	_
22	locate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	uncharted	_	ADJ	_	Degree=Pos	_	_	_	_
26	DNA	_	PROPN	_	Number=Sing	_	_	_	_
27	sequences	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012020	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	ferritin	_	ADJ	_	Degree=Pos	_	_	_	_
6	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	chain	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	:	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	CCAAT	_	PROPN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	Y	_	PROPN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	heme	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	Friend	_	NOUN	_	Number=Sing	_	_	_	_
28	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	during	_	ADP	_	_	_	_	_	_
32	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
37	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ferritin	_	NOUN	_	Number=Sing	_	_	_	_
3	H-chain	_	NOUN	_	Degree=Pos	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	heme	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	Friend	_	NOUN	_	Number=Sing	_	_	_	_
14	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	FLCs	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	during	_	ADP	_	_	_	_	_	_
21	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
26	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	majority	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	lines	_	NOUN	_	Number=Plur	_	_	_	_
7	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	ferritin	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	exerted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	mostly	_	ADV	_	_	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	translational	_	ADJ	_	Degree=Pos	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	SCONJ	_	_	_	_	_	_
4	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
5	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	must	_	AUX	_	VerbForm=Fin	_	_	_	_
10	incorporate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	high	_	ADJ	_	Degree=Pos	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	iron	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	sustain	_	VERB	_	VerbForm=Inf	_	_	_	_
17	hemoglobin	_	NOUN	_	Number=Sing	_	_	_	_
18	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	involved	_	ADJ	_	Degree=Pos	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	iron	_	ADJ	_	Degree=Pos	_	_	_	_
29	storage	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
32	regulation	_	NOUN	_	Number=Sing	_	_	_	_
33	seemed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	to	_	PART	_	_	_	_	_	_
35	be	_	AUX	_	VerbForm=Inf	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
38	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	minimum	_	ADJ	_	Degree=Pos	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	ferritin	_	NOUN	_	Number=Sing	_	_	_	_
11	H	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	able	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	confer	_	VERB	_	VerbForm=Inf	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	regulation	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	heme	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	FLCs	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	reporter	_	NOUN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	77	_	NUM	_	NumType=Card	_	_	_	_
32	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
33	upstream	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	TATA	_	NOUN	_	Number=Sing	_	_	_	_
37	box	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	cis	_	NOUN	_	Number=Sing	_	_	_	_
3	element	_	NOUN	_	Number=Sing	_	_	_	_
4	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	complex	_	NOUN	_	Number=Sing	_	_	_	_
8	referred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	HRF	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	heme	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	greatly	_	ADV	_	_	_	_	_	_
22	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	both	_	CCONJ	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	heme	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	FLCs	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	during	_	ADP	_	_	_	_	_	_
31	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
36	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CCAAT	_	ADJ	_	Number=Sing	_	_	_	_
3	element	_	NOUN	_	Number=Sing	_	_	_	_
4	present	_	VERB	_	VerbForm=Inf	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	reverse	_	NOUN	_	Number=Sing	_	_	_	_
7	orientation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	promoter	_	ADJ	_	Number=Sing	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	ferritin	_	NOUN	_	Number=Sing	_	_	_	_
15	H-chain	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	since	_	SCONJ	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	single	_	ADJ	_	Degree=Pos	_	_	_	_
29	point	_	NOUN	_	Number=Sing	_	_	_	_
30	mutation	_	NOUN	_	Number=Sing	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	able	_	ADJ	_	Degree=Pos	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	abolish	_	VERB	_	VerbForm=Inf	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	binding	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	HRF	_	PROPN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
42	activity	_	NOUN	_	Number=Sing	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	competition	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	supershift	_	NOUN	_	Number=Sing	_	_	_	_
6	assays	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	HRF	_	PROPN	_	Number=Sing	_	_	_	_
13	as	_	SCONJ	_	_	_	_	_	_
14	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	at	_	ADV	_	_	_	_	_	_
16	least	_	ADV	_	Degree=Sup	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	Y.	_	PROPN	_	Number=Sing	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	Y	_	PROPN	_	Number=Sing	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	formed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	three	_	NUM	_	NumType=Card	_	_	_	_
31	subunits	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	A	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	B	_	PROPN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	C	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	all	_	DET	_	_	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	which	_	PRON	_	PronType=Int	_	_	_	_
43	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
44	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
45	for	_	ADP	_	_	_	_	_	_
46	DNA	_	PROPN	_	Number=Sing	_	_	_	_
47	binding	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	transdominant	_	ADJ	_	Degree=Pos	_	_	_	_
5	negative	_	ADJ	_	Degree=Pos	_	_	_	_
6	mutant	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	YA	_	PROPN	_	Number=Sing	_	_	_	_
12	subunit	_	NOUN	_	Number=Sing	_	_	_	_
13	abolishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	heme	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	Y	_	ADV	_	Number=Sing	_	_	_	_
25	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	essential	_	ADJ	_	Degree=Pos	_	_	_	_
28	role	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	differential	_	ADJ	_	Degree=Pos	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	YA	_	PROPN	_	Number=Sing	_	_	_	_
13	subunit	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	heme	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	control	_	VERB	_	Number=Sing	_	_	_	_
20	FLCs	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	during	_	ADP	_	_	_	_	_	_
23	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
28	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012022	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
2	control	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	triggering	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	HLA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	DR	_	PROPN	_	Number=Sing	_	_	_	_
17	antigens	_	NOUN	_	Number=Plur	_	_	_	_
18	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	B	_	ADJ	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	following	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	triggering	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	HLA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	DR	_	PROPN	_	Number=Sing	_	_	_	_
16	antigens	_	NOUN	_	Number=Plur	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	mAb	_	PROPN	_	Number=Sing	_	_	_	_
19	L243	_	PROPN	_	Number=Sing	_	_	_	_
20	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
22	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	at	_	ADP	_	_	_	_	_	_
24	various	_	ADJ	_	Degree=Pos	_	_	_	_
25	times	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	Raji	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	strong	_	ADJ	_	Degree=Pos	_	_	_	_
8	increase	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	DNA	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	after	_	ADP	_	_	_	_	_	_
17	triggering	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	HLA	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	DR	_	PROPN	_	Number=Sing	_	_	_	_
22	antigens	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	TNF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	alpha-activity	_	NOUN	_	Number=Sing	_	_	_	_
5	neutralizing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	authors	_	NOUN	_	Number=Plur	_	_	_	_
10	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	PROPN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	depend	_	VERB	_	VerbForm=Inf	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	at	_	ADP	_	_	_	_	_	_
25	later	_	ADJ	_	Degree=Cmp	_	_	_	_
26	time	_	NOUN	_	Number=Sing	_	_	_	_
27	point	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	autocrine	_	ADJ	_	Degree=Pos	_	_	_	_
32	effect	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	TNF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	following	_	VERB	_	VerbForm=Ger	_	_	_	_
39	triggering	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	HLA	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	DR	_	NOUN	_	Number=Sing	_	_	_	_
44	antigens	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	TNF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	independent	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	early	_	ADJ	_	Degree=Pos	_	_	_	_
16	time	_	NOUN	_	Number=Sing	_	_	_	_
17	point	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	triggering	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	epitopes	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	HLA	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	DR	_	NOUN	_	Number=Sing	_	_	_	_
24	antigens	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	fact	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	mAb	_	PROPN	_	Number=Sing	_	_	_	_
5	L243	_	PROPN	_	Number=Sing	_	_	_	_
6	but	_	CCONJ	_	_	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	staphylococcal	_	ADJ	_	Degree=Pos	_	_	_	_
10	superantigens	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	staphylococcal	_	ADJ	_	Degree=Pos	_	_	_	_
13	exotoxin	_	NOUN	_	Number=Sing	_	_	_	_
14	toxic	_	ADJ	_	Degree=Pos	_	_	_	_
15	shock	_	NOUN	_	Number=Sing	_	_	_	_
16	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
17	toxin	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	staphylococcal	_	ADJ	_	Degree=Pos	_	_	_	_
22	enterotoxin	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	binding	_	NOUN	_	Number=Sing	_	_	_	_
32	activity	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012023	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tissue	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	ecto	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	5	_	NUM	_	NumType=Card	_	_	_	_
10	'-	_	PUNCT	_	_	_	_	_	_
11	nucleotidase	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Role	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	camp	_	NOUN	_	Number=Sing	_	_	_	_
5	response	_	NOUN	_	Number=Sing	_	_	_	_
6	element	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
10	repression	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	'	_	PUNCT	_	_	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	ecto	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	5'-	_	NUM	_	_	_	_	_	_
13	nucleotidase	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	low	_	ADJ	_	Degree=Pos	_	_	_	_
16	K	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	m	_	NOUN	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	5	_	NUM	_	NumType=Card	_	_	_	_
21	'-	_	PUNCT	_	Number=Plur	_	_	_	_
22	NT	_	PART	_	_	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	established	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	969	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	base	_	NOUN	_	Number=Sing	_	_	_	_
32	pair	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	bp	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	fragment	_	NOUN	_	Number=Sing	_	_	_	_
37	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	specific	_	ADJ	_	Degree=Pos	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	CAT	_	NOUN	_	Number=Sing	_	_	_	_
45	reporter	_	NOUN	_	Number=Sing	_	_	_	_
46	gene	_	NOUN	_	Number=Sing	_	_	_	_
47	that	_	PRON	_	PronType=Rel	_	_	_	_
48	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	with	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	expression	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
54	ecto-5	_	NOUN	_	Number=Sing	_	_	_	_
55	'-	_	PUNCT	_	_	_	_	_	_
56	NT	_	PART	_	_	_	_	_	_
57	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
58	and	_	CCONJ	_	_	_	_	_	_
59	enzymatic	_	ADJ	_	Degree=Pos	_	_	_	_
60	activity	_	NOUN	_	Number=Sing	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	768	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	bp	_	NOUN	_	Number=Sing	_	_	_	_
5	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
6	negative	_	ADJ	_	Degree=Pos	_	_	_	_
7	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	region	_	NOUN	_	Number=Sing	_	_	_	_
9	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	conferred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	negative	_	ADJ	_	Degree=Pos	_	_	_	_
18	regulation	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
22	system	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	244	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	bp	_	NOUN	_	Number=Sing	_	_	_	_
28	deoxycytidine	_	NOUN	_	Number=Sing	_	_	_	_
29	kinase	_	NOUN	_	Number=Sing	_	_	_	_
30	core	_	NOUN	_	Number=Sing	_	_	_	_
31	promoter	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	DNase	_	PROPN	_	Number=Sing	_	_	_	_

1	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
2	footprinting	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	several	_	ADJ	_	Degree=Pos	_	_	_	_
5	protected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	areas	_	NOUN	_	Number=Plur	_	_	_	_
7	including	_	VERB	_	VerbForm=Ger	_	_	_	_
8	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	AP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	element	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	CRE	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	binding	_	VERB	_	Number=Sing	_	_	_	_
24	sites	_	NOUN	_	Number=Plur	_	_	_	_
25	within	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	201	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	bp	_	NOUN	_	Number=Sing	_	_	_	_
30	core	_	NOUN	_	Number=Sing	_	_	_	_
31	promoter	_	NOUN	_	Number=Sing	_	_	_	_
32	region	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	NRE	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2a	_	PROPN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	TCF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	/	_	PUNCT	_	_	_	_	_	_
44	LEF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	Sp1/NF	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	AT	_	ADP	_	_	_	_	_	_
52	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
53	sites	_	NOUN	_	Number=Plur	_	_	_	_
54	in	_	ADP	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
57	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
58	region	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	CRE	_	NOUN	_	Number=Sing	_	_	_	_
4	site	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	essential	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	SCONJ	_	_	_	_	_	_
8	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	negative	_	ADJ	_	Degree=Pos	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	mutation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	AP	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	site	_	NOUN	_	Number=Sing	_	_	_	_
34	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	activity	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	both	_	DET	_	_	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	lines	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	CRE	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	ATF	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	ATF	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
4	12	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	myristate	_	NOUN	_	Number=Sing	_	_	_	_
7	13	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	acetate	_	NOUN	_	Number=Sing	_	_	_	_
10	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	core	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	969	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	bp	_	NOUN	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	fragments	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
27	increase	_	NOUN	_	Number=Sing	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	abrogated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	mutations	_	NOUN	_	Number=Plur	_	_	_	_
32	at	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	CRE	_	NOUN	_	Number=Sing	_	_	_	_
35	site	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	summary	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	tissue	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	5'	_	NOUN	_	NumType=Card	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	ecto	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	5	_	NUM	_	NumType=Card	_	_	_	_
19	'-	_	PUNCT	_	_	_	_	_	_
20	NT	_	PART	_	_	_	_	_	_
21	core	_	NOUN	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	presence	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	functional	_	ADJ	_	Degree=Pos	_	_	_	_
30	CRE	_	NOUN	_	Number=Sing	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	within	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	basal	_	ADJ	_	Degree=Pos	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
38	suppressive	_	ADJ	_	Degree=Pos	_	_	_	_
39	activity	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012031	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	new	_	ADJ	_	Degree=Pos	_	_	_	_
5	isoform	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	family	_	NOUN	_	Number=Sing	_	_	_	_
19	member	_	NOUN	_	Number=Sing	_	_	_	_
20	NFATc	_	PROPN	_	Number=Sing	_	_	_	_
21	[	_	PUNCT	_	_	_	_	_	_
22	published	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	erratum	_	NOUN	_	Number=Sing	_	_	_	_
24	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	J	_	PROPN	_	Number=Sing	_	_	_	_
27	Biol	_	PROPN	_	Number=Sing	_	_	_	_
28	Chem	_	PROPN	_	Number=Sing	_	_	_	_
29	1996	_	NUM	_	NumType=Card	_	_	_	_
30	Dec	_	PROPN	_	Number=Sing	_	_	_	_
31	27;271	_	NUM	_	NumType=Card	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	52	_	NUM	_	NumType=Card	_	_	_	_
34	):33705	_	NUM	_	NumType=Card	_	_	_	_
35	]	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
3	A	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	CsA	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	FK506	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	key	_	ADJ	_	Degree=Pos	_	_	_	_
23	role	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	cytokine	_	ADJ	_	Degree=Pos	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	T	_	PROPN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	recently	_	ADV	_	_	_	_	_	_
6	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	several	_	ADJ	_	Degree=Pos	_	_	_	_
12	non-T	_	ADJ	_	Degree=Pos	_	_	_	_
13	immune	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	NFAT	_	ADJ	_	Degree=Pos	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	family	_	NOUN	_	Number=Sing	_	_	_	_
20	members	_	NOUN	_	Number=Plur	_	_	_	_
21	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	date	_	NOUN	_	Number=Sing	_	_	_	_
24	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	only	_	ADV	_	_	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	T	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
4	NFAT	_	ADJ	_	Number=Sing	_	_	_	_
5	function	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	demonstrate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	specificity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
21	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	here	_	ADV	_	PronType=Dem	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	isolation	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	characterization	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
30	clone	_	NOUN	_	Number=Sing	_	_	_	_
31	from	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	Raji	_	PROPN	_	Number=Sing	_	_	_	_
34	B	_	PROPN	_	Number=Sing	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	line	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
3	clone	_	NOUN	_	Number=Sing	_	_	_	_
4	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	new	_	ADJ	_	Degree=Pos	_	_	_	_
7	isoform	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	NFATc.beta	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	NFAT	_	PROPN	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	family	_	NOUN	_	Number=Sing	_	_	_	_
16	member	_	NOUN	_	Number=Sing	_	_	_	_
17	NFATc	_	PROPN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	here	_	ADV	_	PronType=Dem	_	_	_	_
21	NFATc.alpha	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	amino	_	NOUN	_	Number=Sing	_	_	_	_
3	acid	_	NOUN	_	Number=Sing	_	_	_	_
4	sequence	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NFATc.	_	PROPN	_	Number=Sing	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	differs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NFATc.	_	PROPN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
17	NH2	_	NUM	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	terminal	_	NOUN	_	Number=Sing	_	_	_	_
20	29	_	NUM	_	NumType=Card	_	_	_	_
21	residues	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	additional	_	ADJ	_	Degree=Pos	_	_	_	_
26	region	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	142	_	NUM	_	NumType=Card	_	_	_	_
29	residues	_	NOUN	_	Number=Plur	_	_	_	_
30	at	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	COOH	_	PROPN	_	Number=Sing	_	_	_	_
33	terminus	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	using	_	VERB	_	VerbForm=Ger	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	probe	_	NOUN	_	Number=Sing	_	_	_	_
6	encompassing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	common	_	ADJ	_	Degree=Pos	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	both	_	DET	_	_	_	_	_	_
12	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
13	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	two	_	NUM	_	NumType=Card	_	_	_	_
15	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
16	species	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	2.7	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	4.5	_	NUM	_	NumType=Card	_	_	_	_
21	kilobase	_	NOUN	_	Number=Sing	_	_	_	_
22	pairs	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	while	_	SCONJ	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	NFATc.beta-specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	probe	_	NOUN	_	Number=Sing	_	_	_	_
28	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	only	_	ADV	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	4.5	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kilobase	_	NOUN	_	Number=Sing	_	_	_	_
34	pair	_	NOUN	_	Number=Sing	_	_	_	_
35	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
36	which	_	PRON	_	PronType=Rel	_	_	_	_
37	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
38	preferentially	_	ADV	_	_	_	_	_	_
39	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	spleen	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NFATc.beta	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	capable	_	ADJ	_	Degree=Pos	_	_	_	_
7	of	_	SCONJ	_	_	_	_	_	_
8	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	interleukin	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	reporter	_	NOUN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	CsA	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
27	manner	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	NFATc.beta	_	PROPN	_	Number=Sing	_	_	_	_
4	neither	_	CCONJ	_	_	_	_	_	_
5	bound	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	kappa3	_	NOUN	_	Number=Sing	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	tumor	_	NOUN	_	Number=Sing	_	_	_	_
20	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	nor	_	CCONJ	_	_	_	_	_	_
26	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	tumor	_	NOUN	_	Number=Sing	_	_	_	_
29	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	alpha	_	NOUN	_	Number=Sing	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
36	assays	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	different	_	ADJ	_	Degree=Pos	_	_	_	_
6	members	_	NOUN	_	Number=Plur	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NFAT	_	ADJ	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	family	_	NOUN	_	Number=Sing	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
15	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	different	_	ADJ	_	Degree=Pos	_	_	_	_
19	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012032	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
2	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
3	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
13	mediators	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	cultured	_	VERB	_	Degree=Pos	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	dermal	_	ADJ	_	Degree=Pos	_	_	_	_
18	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
2	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	LPS	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	immune	_	ADJ	_	Number=Sing	_	_	_	_
9	responses	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	including	_	VERB	_	VerbForm=Ger	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	play	_	VERB	_	VerbForm=Inf	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	important	_	ADJ	_	Degree=Pos	_	_	_	_
25	role	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	Gram	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	negative	_	ADJ	_	Degree=Pos	_	_	_	_
33	bacteria	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
37	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
13	release	_	NOUN	_	Number=Sing	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	LPS	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	critical	_	ADJ	_	Degree=Pos	_	_	_	_
22	step	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	endotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
25	effects	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	involvement	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	tumor	_	NOUN	_	Number=Sing	_	_	_	_
19	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	TNF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	signal	_	NOUN	_	Number=Sing	_	_	_	_
27	transducer	_	NOUN	_	Number=Sing	_	_	_	_
28	molecules	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	LPS	_	NOUN	_	Number=Sing	_	_	_	_
31	signaling	_	VERB	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	human	_	ADJ	_	Degree=Pos	_	_	_	_
34	dermal	_	ADJ	_	Number=Sing	_	_	_	_
35	microvessel	_	NOUN	_	Number=Sing	_	_	_	_
36	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	HDMEC	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	THP	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	PROPN	_	Number=Sing	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HDMEC	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	THP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	like	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	signaling	_	NOUN	_	Number=Sing	_	_	_	_
22	cascade	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	transient	_	ADJ	_	Degree=Pos	_	_	_	_
3	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
4	experiments	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
7	negative	_	ADJ	_	Degree=Pos	_	_	_	_
8	mutants	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	signaling	_	NOUN	_	Number=Sing	_	_	_	_
15	pathway	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	including	_	VERB	_	VerbForm=Ger	_	_	_	_
18	MyD88	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	IRAK	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	IRAK2	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	TRAF6	_	PROPN	_	Number=Sing	_	_	_	_
26	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	both	_	CCONJ	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	LPS	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
41	activity	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
14	negative	_	ADJ	_	Degree=Pos	_	_	_	_
15	mutant	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	involved	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	TNF	_	PROPN	_	Number=Sing	_	_	_	_
23	signaling	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
11	reporter	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	TLR2	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	TLR4	_	PROPN	_	Number=Sing	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	surface	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	HDMEC	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	THP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	signal	_	ADJ	_	Number=Sing	_	_	_	_
7	transduction	_	NOUN	_	Number=Sing	_	_	_	_
8	molecule	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	LPS	_	NOUN	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	complex	_	NOUN	_	Number=Sing	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	belong	_	VERB	_	VerbForm=Inf	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	toll	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	like	_	ADJ	_	Degree=Pos	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	TLR	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	super	_	ADV	_	_	_	_	_	_
31	family	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	LPS	_	PROPN	_	Number=Sing	_	_	_	_
36	signaling	_	NOUN	_	Number=Sing	_	_	_	_
37	cascade	_	NOUN	_	Number=Sing	_	_	_	_
38	uses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	analogous	_	ADJ	_	Degree=Pos	_	_	_	_
41	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
42	framework	_	NOUN	_	Number=Sing	_	_	_	_
43	for	_	ADP	_	_	_	_	_	_
44	signaling	_	NOUN	_	Number=Sing	_	_	_	_
45	as	_	ADP	_	_	_	_	_	_
46	IL	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	1	_	NUM	_	NumType=Card	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
51	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
54	cells	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012035	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	toll	_	NOUN	_	Number=Sing	_	_	_	_
4	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
5	pathway	_	NOUN	_	Number=Sing	_	_	_	_
6	:	_	PUNCT	_	_	_	_	_	_
7	divergence	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	JNK	_	PROPN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	SAPK	_	PROPN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	upstream	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	tumor	_	NOUN	_	Number=Sing	_	_	_	_
20	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	6	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	TRAF6	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	homologue	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Drosophila	_	PROPN	_	Number=Sing	_	_	_	_
6	Toll	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	hToll	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	recently	_	ADV	_	_	_	_	_	_
13	cloned	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1R	_	NUM	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
30	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	adaptive	_	ADJ	_	Degree=Pos	_	_	_	_
36	immunity	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	hToll	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	sequential	_	ADJ	_	Degree=Pos	_	_	_	_
10	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	adapter	_	NOUN	_	Number=Sing	_	_	_	_
14	molecule	_	NOUN	_	Number=Sing	_	_	_	_
15	MyD88	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1R	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	TRAF6	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	kinase	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	NIK	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	both	_	ADV	_	_	_	_	_	_
30	involved	_	ADJ	_	Degree=Pos	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
33	steps	_	NOUN	_	Number=Plur	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
38	activation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Conversely	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
5	negative	_	ADJ	_	Degree=Pos	_	_	_	_
6	version	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	TRAF6	_	PROPN	_	Number=Sing	_	_	_	_
9	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	block	_	VERB	_	VerbForm=Inf	_	_	_	_
12	hToll	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	stress	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	kinase	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	c	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	Jun	_	PROPN	_	Number=Sing	_	_	_	_
26	NH2	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
29	kinases	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	thus	_	ADV	_	_	_	_	_	_
32	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	early	_	ADJ	_	Degree=Pos	_	_	_	_
35	divergence	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	two	_	NUM	_	NumType=Card	_	_	_	_
39	pathways	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012037	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	specific	_	ADJ	_	Degree=Pos	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	Bruton	_	PROPN	_	Number=Sing	_	_	_	_
7	's	_	PART	_	_	_	_	_	_
8	agammaglobulinemia	_	NOUN	_	Number=Sing	_	_	_	_
9	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
10	kinase	_	NOUN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	Btk	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	Spi-1	_	NUM	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	family	_	NOUN	_	Number=Sing	_	_	_	_
26	members	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Bruton	_	PROPN	_	Number=Sing	_	_	_	_
2	's	_	PART	_	_	_	_	_	_
3	agammaglobulinemia	_	PROPN	_	Number=Sing	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	Btk	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
12	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	involved	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	disease	_	NOUN	_	Number=Sing	_	_	_	_
19	X	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	agammaglobulinemia	_	PROPN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	XLA	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	all	_	DET	_	_	_	_	_	_
7	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	exception	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	plasma	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	pattern	_	NOUN	_	Number=Sing	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	280	_	NUM	_	NumType=Card	_	_	_	_
8	bp	_	NOUN	_	Number=Sing	_	_	_	_
9	upstream	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	major	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	start	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	footprinting	_	VERB	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	within	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	part	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	two	_	NUM	_	NumType=Card	_	_	_	_
13	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	VerbForm=Ger	_	_	_	_
15	sites	_	NOUN	_	Number=Plur	_	_	_	_
16	as	_	ADV	_	_	_	_	_	_
17	well	_	ADV	_	Degree=Pos	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	PU	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	box	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	Spi-1	_	NUM	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
7	as	_	ADV	_	_	_	_	_	_
8	well	_	ADV	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	closely	_	ADV	_	_	_	_	_	_
12	related	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	Spi-B	_	NOUN	_	Number=Sing	_	_	_	_
15	bound	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	PU	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	box	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	erythroleukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	line	_	NOUN	_	Number=Sing	_	_	_	_
6	K562	_	NOUN	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	due	_	ADP	_	_	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	absence	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Spi-B	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	only	_	ADV	_	_	_	_	_	_
16	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
17	bound	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	Btk	_	NOUN	_	Number=Sing	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	either	_	DET	_	_	_	_	_	_
4	site	_	NOUN	_	Number=Sing	_	_	_	_
5	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	transient	_	ADJ	_	Degree=Pos	_	_	_	_
10	transfection	_	NOUN	_	Number=Sing	_	_	_	_
11	experiments	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	mutation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	PU	_	PROPN	_	Number=Sing	_	_	_	_
7	box	_	NOUN	_	Number=Sing	_	_	_	_
8	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	no	_	DET	_	_	_	_	_	_
10	effect	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
14	line	_	NOUN	_	Number=Sing	_	_	_	_
15	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	where	_	ADV	_	PronType=Rel	_	_	_	_
18	none	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	Spi	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	family	_	NOUN	_	Number=Sing	_	_	_	_
25	members	_	NOUN	_	Number=Plur	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	Spi-B	_	NOUN	_	Number=Sing	_	_	_	_
4	as	_	ADV	_	_	_	_	_	_
5	well	_	ADV	_	Degree=Pos	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	able	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	Btk	_	PROPN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	fetal	_	ADJ	_	Number=Sing	_	_	_	_
3	liver	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
6	-/-	_	PUNCT	_	_	_	_	_	_
7	mice	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	lack	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	Btk	_	PROPN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	two	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	threefold	_	NOUN	_	Number=Sing	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	not	_	ADV	_	_	_	_	_	_
27	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Collectively	_	ADV	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Btk	_	PROPN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	action	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	family	_	NOUN	_	Number=Sing	_	_	_	_
24	members	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012047	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	neuroblastoma	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	lines	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	eukaryotic	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	B	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
6	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	constitutively	_	ADV	_	_	_	_	_	_
9	present	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	whereas	_	SCONJ	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	many	_	ADJ	_	Degree=Pos	_	_	_	_
17	other	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	types	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	translocates	_	NOUN	_	Number=Plur	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	result	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	transduction	_	NOUN	_	Number=Sing	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	tumor	_	NOUN	_	Number=Sing	_	_	_	_
37	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
38	factor	_	NOUN	_	Number=Sing	_	_	_	_
39	alpha	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	TNF	_	PROPN	_	Number=Sing	_	_	_	_
42	alpha	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
46	ester	_	NOUN	_	Number=Sing	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	other	_	ADJ	_	Degree=Pos	_	_	_	_
50	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
51	signals	_	NOUN	_	Number=Plur	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	neuroblastoma	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	models	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	neural	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	present	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	translocated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	into	_	ADP	_	_	_	_	_	_
27	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	result	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	TNF	_	ADJ	_	Number=Sing	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	treatment	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	TNF	_	PROPN	_	Number=Sing	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	transcriptionally	_	ADV	_	_	_	_	_	_
12	functional	_	ADJ	_	Degree=Pos	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	correlated	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	reagents	_	NOUN	_	Number=Plur	_	_	_	_
4	such	_	ADJ	_	Degree=Pos	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	nerve	_	ADJ	_	Degree=Pos	_	_	_	_
7	growth	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	NGF	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
15	ester	_	NOUN	_	Number=Sing	_	_	_	_
16	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
17	12	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	myristate	_	NOUN	_	Number=Sing	_	_	_	_
20	13	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	acetate	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	PMA	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	phenotypical	_	ADJ	_	Degree=Pos	_	_	_	_
30	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	SH	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	SY5Y	_	NOUN	_	Number=Sing	_	_	_	_
36	neuroblastoma	_	NOUN	_	Number=Sing	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	line	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	NF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	kappa	_	NOUN	_	Number=Sing	_	_	_	_
44	B	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	but	_	CCONJ	_	_	_	_	_	_
47	only	_	ADV	_	_	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
50	particular	_	ADJ	_	Degree=Pos	_	_	_	_
51	cell	_	NOUN	_	Number=Sing	_	_	_	_
52	line	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	NGF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
6	rat	_	NOUN	_	Number=Sing	_	_	_	_
7	pheochromocytoma	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	line	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	PC12	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	PMA	_	PROPN	_	Number=Sing	_	_	_	_
14	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	PROPN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	whereas	_	SCONJ	_	_	_	_	_	_
21	NGF	_	PROPN	_	Number=Sing	_	_	_	_
22	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	neuroblastoma	_	NOUN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	lines	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	such	_	ADJ	_	Degree=Pos	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	SK	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	N	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	Be	_	PROPN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	2	_	X	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	lack	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	PMA	_	PROPN	_	Number=Sing	_	_	_	_
22	induction	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	lack	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	activation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	moreover	_	ADV	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	SK	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	N-Be	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	2	_	X	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	kinase	_	NOUN	_	Number=Sing	_	_	_	_
17	C	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	PKC	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	enzymatic	_	ADJ	_	Degree=Pos	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	much	_	ADV	_	_	_	_	_	_
25	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
26	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	control	_	NOUN	_	Number=Sing	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	line	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	that	_	SCONJ	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	low	_	ADJ	_	Degree=Pos	_	_	_	_
38	PKC	_	NOUN	_	Number=Sing	_	_	_	_
39	enzymatic	_	ADJ	_	Number=Sing	_	_	_	_
40	activity	_	NOUN	_	Number=Sing	_	_	_	_
41	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
42	due	_	ADP	_	_	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	low	_	ADJ	_	Degree=Pos	_	_	_	_
45	PKC	_	PROPN	_	Number=Sing	_	_	_	_
46	protein	_	NOUN	_	Number=Sing	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
10	acid	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	morphological	_	ADJ	_	Degree=Pos	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	all	_	DET	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	neuroblastoma	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	lines	_	NOUN	_	Number=Plur	_	_	_	_
22	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	present	_	ADJ	_	Degree=Pos	_	_	_	_
26	study	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	neuroblastoma	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	proved	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	induction	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	neuroblastoma	_	NOUN	_	Number=Sing	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012050	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Specific	_	ADJ	_	Degree=Pos	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	subunits	_	NOUN	_	Number=Plur	_	_	_	_
7	act	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	concert	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	Tat	_	PROPN	_	Number=Sing	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	complex	_	NOUN	_	Number=Sing	_	_	_	_
9	which	_	DET	_	PronType=Rel	_	_	_	_
10	functions	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	concert	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	tat	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	gene	_	VERB	_	Number=Sing	_	_	_	_
19	product	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
24	virus	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	HIV	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	members	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	family	_	NOUN	_	Number=Sing	_	_	_	_
13	contribute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	effect	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	abilities	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	different	_	ADJ	_	Degree=Pos	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	subunits	_	NOUN	_	Number=Plur	_	_	_	_
30	to	_	PART	_	_	_	_	_	_
31	act	_	VERB	_	VerbForm=Inf	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	Tat	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	HIV	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
43	T-leukemia	_	PROPN	_	Number=Sing	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	p49(100	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	DNA	_	PROPN	_	Number=Sing	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	subunit	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	together	_	ADV	_	_	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	p65	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	can	_	AUX	_	VerbForm=Fin	_	_	_	_
17	act	_	VERB	_	VerbForm=Inf	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	concert	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	Tat	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	HIV	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	CAT	_	NOUN	_	Number=Sing	_	_	_	_
32	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Little	_	ADJ	_	Degree=Pos	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	50	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kDa	_	NOUN	_	Number=Sing	_	_	_	_
9	forms	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	p105	_	NUM	_	Number=Sing	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	rel	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	combination	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	p65	_	NOUN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	full	_	ADJ	_	Degree=Pos	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	length	_	NOUN	_	Number=Sing	_	_	_	_
27	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	not	_	PART	_	_	_	_	_	_
32	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	HIV	_	PROPN	_	Number=Sing	_	_	_	_
35	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	combination	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	p49(100	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	p65	_	NUM	_	Number=Sing	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	can	_	AUX	_	VerbForm=Fin	_	_	_	_
17	act	_	VERB	_	VerbForm=Inf	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	concert	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	tat	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	gene	_	VERB	_	Number=Sing	_	_	_	_
26	product	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	HIV	_	NOUN	_	Number=Sing	_	_	_	_
33	RNA	_	PROPN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012057	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cobalt	_	NOUN	_	Number=Sing	_	_	_	_
2	chloride	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	signaling	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
8	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	adherence	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	sickle	_	ADJ	_	Degree=Pos	_	_	_	_
15	red	_	ADJ	_	Degree=Pos	_	_	_	_
16	blood	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	transendothelial	_	ADJ	_	Degree=Pos	_	_	_	_
20	migration	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	like	_	ADP	_	_	_	_	_	_
25	HL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	60	_	NUM	_	NumType=Card	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	PAF	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	receptor	_	NOUN	_	Number=Sing	_	_	_	_
35	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	response	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	sickle	_	ADJ	_	Degree=Pos	_	_	_	_
7	red	_	ADJ	_	Degree=Pos	_	_	_	_
8	blood	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	SS	_	PROPN	_	Number=Sing	_	_	_	_
12	RBC	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	exhibit	_	NOUN	_	Number=Sing	_	_	_	_
17	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	adherence	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
22	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	while	_	SCONJ	_	_	_	_	_	_
25	diapedesis	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	through	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	blood	_	NOUN	_	Number=Sing	_	_	_	_
31	vessel	_	NOUN	_	Number=Sing	_	_	_	_
32	increases	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	signaling	_	NOUN	_	Number=Sing	_	_	_	_
6	pathway	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	s	_	X	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	poorly	_	ADV	_	_	_	_	_	_
15	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	utilized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	CoCl2	_	PROPN	_	Number=Sing	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	mimetic	_	ADJ	_	Degree=Pos	_	_	_	_
7	molecule	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	study	_	VERB	_	VerbForm=Inf	_	_	_	_
12	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
13	signaling	_	NOUN	_	Number=Sing	_	_	_	_
14	pathways	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
7	vein	_	NOUN	_	Number=Sing	_	_	_	_
8	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	HUVEC	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	CoCl2	_	NOUN	_	Number=Sing	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	mM	_	NOUN	_	NumType=Card	_	_	_	_
18	concentration	_	NOUN	_	Number=Sing	_	_	_	_
19	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	surface	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	subset	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	CAMs	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	transcription	_	NOUN	_	Number=Sing	_	_	_	_
37	factor	_	NOUN	_	Number=Sing	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
44	extracts	_	NOUN	_	Number=Plur	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	HUVEC	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CoCl2	_	PROPN	_	Number=Sing	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	time	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
10	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	MAP	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	kinase	_	NOUN	_	Number=Sing	_	_	_	_
20	isoform	_	NOUN	_	Number=Sing	_	_	_	_
21	ERK2	_	NOUN	_	Number=Sing	_	_	_	_
22	without	_	SCONJ	_	_	_	_	_	_
23	significantly	_	ADV	_	_	_	_	_	_
24	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	ERK1	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
28	ERK2	_	PROPN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	preferred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	substrate	_	NOUN	_	Number=Sing	_	_	_	_
33	for	_	ADP	_	_	_	_	_	_
34	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
35	kinase	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
39	pathway	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	MAP	_	NOUN	_	Number=Sing	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	PD98059	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	platelet	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	activating	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	PAF	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	CV3988	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	CoCl2	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	led	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	SS	_	NOUN	_	Number=Sing	_	_	_	_
11	RBC	_	PROPN	_	Number=Sing	_	_	_	_
12	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	inhibitable	_	ADJ	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	antibody	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CoCl2	_	PROPN	_	Number=Sing	_	_	_	_
4	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	threefold	_	VERB	_	Degree=Pos	_	_	_	_
10	increase	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	rate	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	transendothelial	_	ADJ	_	Degree=Pos	_	_	_	_
16	migration	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	like	_	ADP	_	_	_	_	_	_
21	HL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	60	_	NUM	_	NumType=Card	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	twentyfold	_	NOUN	_	Number=Sing	_	_	_	_
28	increase	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	platelet	_	NOUN	_	Number=Sing	_	_	_	_
33	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
36	molecules	_	NOUN	_	Number=Plur	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	PECAM	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transendothelial	_	ADJ	_	Degree=Pos	_	_	_	_
3	migration	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	antibody	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	PECAM	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	PECAM	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	transendothelial	_	ADJ	_	Degree=Pos	_	_	_	_
9	migration	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	CoCl2	_	PROPN	_	Number=Sing	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	GF109203X	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
30	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	Calyculin	_	PROPN	_	Number=Sing	_	_	_	_
33	A	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CoCl2	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
9	signals	_	NOUN	_	Number=Plur	_	_	_	_
10	directing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	HUVEC	_	PROPN	_	Number=Sing	_	_	_	_
19	involve	_	VERB	_	Degree=Pos	_	_	_	_
20	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	MAP	_	NOUN	_	Number=Sing	_	_	_	_
24	kinase	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	while	_	SCONJ	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	PECAM	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	as	_	ADP	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	result	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	activation	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	PKC	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	PAF	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	CoCl2	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	increase	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	SS	_	NOUN	_	Number=Sing	_	_	_	_
22	RBC	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	PECAM	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
32	transendothelial	_	NOUN	_	Number=Sing	_	_	_	_
33	migration	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012061	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tap	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	cellular	_	NOUN	_	Degree=Pos	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	tip	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
13	saimiri	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
17	aggregation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Tip	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
4	saimiri	_	NOUN	_	Number=Sing	_	_	_	_
5	associates	_	VERB	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	Lck	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	down	_	ADV	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	regulates	_	VERB	_	Number=Plur	_	_	_	_
12	Lck	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	VERB	_	Degree=Pos	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
6	Tip	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	Tap	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	yeast	_	ADJ	_	Number=Sing	_	_	_	_
16	two	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
19	screen	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Tap	_	NOUN	_	Number=Sing	_	_	_	_
2	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	Tip	_	NOUN	_	Number=Sing	_	_	_	_
5	following	_	VERB	_	VerbForm=Ger	_	_	_	_
6	transient	_	ADJ	_	Degree=Pos	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	COS	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	stable	_	ADJ	_	Degree=Pos	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	Jurkat	_	NOUN	_	Number=Sing	_	_	_	_
19	-T	_	NOUN	_	_	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Tip	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Tap	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
8	-T	_	PUNCT	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	aggregation	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Aggregation	_	NOUN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	likely	_	ADV	_	_	_	_	_	_
4	caused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	up	_	ADJ	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	surface	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
14	molecules	_	NOUN	_	Number=Plur	_	_	_	_
15	including	_	VERB	_	VerbForm=Ger	_	_	_	_
16	integrin	_	PROPN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	L	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	selectin	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	3	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	H-CAM	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	aggregated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	approximately	_	ADV	_	_	_	_	_	_
13	40	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
16	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	parental	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_

1	Tap	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	likely	_	ADV	_	_	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	important	_	ADJ	_	Degree=Pos	_	_	_	_
8	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
9	mediator	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Tip	_	NOUN	_	Number=Sing	_	_	_	_
12	function	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	transformation	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
19	saimiri	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012064	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	type	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	tumor	_	NOUN	_	Number=Sing	_	_	_	_
11	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	B	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	ATF	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2/JUN	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	tumor	_	NOUN	_	Number=Sing	_	_	_	_
4	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	alpha	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	one	_	NUM	_	NumType=Card	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	earliest	_	ADJ	_	Degree=Sup	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	transcribed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	after	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	through	_	ADP	_	_	_	_	_	_
28	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
29	antigen	_	NOUN	_	Number=Sing	_	_	_	_
30	receptor	_	NOUN	_	Number=Sing	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	via	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	CD	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	40	_	NUM	_	NumType=Card	_	_	_	_
37	pathway	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	both	_	DET	_	_	_	_	_	_
3	cases	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	immunosuppressants	_	NOUN	_	Number=Plur	_	_	_	_
18	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
19	A	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	FK506	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	role	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	NFAT	_	ADJ	_	Number=Sing	_	_	_	_
30	family	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	regulation	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	B	_	ADJ	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	molecules	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
11	bind	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	element	_	NOUN	_	Number=Sing	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	association	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	ATF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	Jun	_	PROPN	_	Number=Sing	_	_	_	_
29	proteins	_	NOUN	_	Number=Plur	_	_	_	_
30	bound	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	immediately	_	ADV	_	_	_	_	_	_
34	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
35	cyclic	_	ADJ	_	Number=Sing	_	_	_	_
36	AMP	_	NOUN	_	Number=Sing	_	_	_	_
37	response	_	NOUN	_	Number=Sing	_	_	_	_
38	element	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	CRE	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	site	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	using	_	VERB	_	VerbForm=Ger	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	murine	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	A20	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	TNF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	type	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	specific	_	ADJ	_	Degree=Pos	_	_	_	_
31	manner	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	A20	_	PROPN	_	Number=Sing	_	_	_	_
3	B	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
16	bound	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	element	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Instead	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	ATF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	Jun	_	PROPN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	bind	_	VERB	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	composite	_	ADJ	_	Degree=Pos	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	3/CRE	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
18	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	newly	_	ADV	_	_	_	_	_	_
22	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
24	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	centered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	at	_	ADP	_	_	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	76	_	NUM	_	NumType=Card	_	_	_	_
30	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
31	relative	_	ADV	_	_	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	TNF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	start	_	NOUN	_	Number=Sing	_	_	_	_
39	site	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	new	_	ADJ	_	Degree=Pos	_	_	_	_
3	site	_	NOUN	_	Number=Sing	_	_	_	_
4	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	critical	_	ADJ	_	Degree=Pos	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	calcium	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	cyclosporin	_	VERB	_	Number=Sing	_	_	_	_
15	A	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	TNF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	both	_	CCONJ	_	_	_	_	_	_
25	A20	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	Ar	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	5	_	NUM	_	NumType=Card	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	quantitative	_	ADJ	_	Degree=Pos	_	_	_	_
7	DNase	_	NOUN	_	Number=Sing	_	_	_	_
8	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	using	_	VERB	_	VerbForm=Ger	_	_	_	_
16	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	amounts	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	recombinant	_	ADJ	_	Number=Sing	_	_	_	_
20	NFATp	_	PROPN	_	Number=Sing	_	_	_	_
21	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	76	_	NUM	_	NumType=Card	_	_	_	_
26	site	_	NOUN	_	Number=Sing	_	_	_	_
27	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	NFATp	_	VERB	_	Number=Sing	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
33	affinity	_	NOUN	_	Number=Sing	_	_	_	_
34	than	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	kappa	_	PROPN	_	Number=Sing	_	_	_	_
37	3	_	NUM	_	NumType=Card	_	_	_	_
38	site	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	unrecognized	_	ADJ	_	Degree=Pos	_	_	_	_
5	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
8	sites	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	also	_	ADV	_	_	_	_	_	_
18	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	analysis	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	through	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	differential	_	ADJ	_	Degree=Pos	_	_	_	_
6	use	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	same	_	ADJ	_	Degree=Pos	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	element	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	composite	_	ADJ	_	Number=Sing	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	3/CRE	_	NOUN	_	Number=Sing	_	_	_	_
17	site	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	TNF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	type	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	specific	_	ADJ	_	Degree=Pos	_	_	_	_
33	manner	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	response	_	NOUN	_	Number=Sing	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	same	_	ADJ	_	Degree=Pos	_	_	_	_
39	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
40	signal	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012069	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
5	germline	_	NOUN	_	Number=Sing	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	:	_	PUNCT	_	_	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	activator	_	NOUN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Germline	_	NOUN	_	Number=Sing	_	_	_	_
2	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
3	initiate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	promoters	_	NOUN	_	Number=Plur	_	_	_	_
6	upstream	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
10	switch	_	NOUN	_	Number=Sing	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	target	_	VERB	_	VerbForm=Inf	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	appropriate	_	ADJ	_	Degree=Pos	_	_	_	_
20	switch	_	NOUN	_	Number=Sing	_	_	_	_
21	region	_	NOUN	_	Number=Sing	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	recombination	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	switching	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Different	_	ADJ	_	Degree=Pos	_	_	_	_
2	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
3	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	appropriate	_	ADJ	_	Degree=Pos	_	_	_	_
8	germline	_	NOUN	_	Number=Sing	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
3	sites	_	NOUN	_	Number=Plur	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	B-	_	PUNCT	_	NumType=Card	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	activator	_	NOUN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	BSAP	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	upstream	_	ADP	_	_	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	several	_	ADJ	_	Degree=Pos	_	_	_	_
19	switch	_	NOUN	_	Number=Sing	_	_	_	_
20	regions	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
24	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
25	chain	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	cluster	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	BSAP	_	PROPN	_	Number=Sing	_	_	_	_
30	might	_	AUX	_	VerbForm=Fin	_	_	_	_
31	play	_	VERB	_	VerbForm=Inf	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	role	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	regulation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	germline	_	NOUN	_	Number=Sing	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	isotype	_	NOUN	_	Number=Sing	_	_	_	_
42	switching	_	VERB	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	BSAP	_	PROPN	_	Number=Sing	_	_	_	_
5	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
15	germline	_	NOUN	_	Number=Sing	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	BSAP	_	PROPN	_	Number=Sing	_	_	_	_
6	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	CD40	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
21	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
25	germline	_	NOUN	_	Number=Sing	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	BSAP	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	unique	_	ADJ	_	Degree=Pos	_	_	_	_
4	among	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
11	germline	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	because	_	SCONJ	_	_	_	_	_	_
15	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	B	_	DET	_	NumType=Card	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	at	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	merging	_	NOUN	_	Number=Sing	_	_	_	_
26	point	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	two	_	NUM	_	NumType=Card	_	_	_	_
29	signalling	_	NOUN	_	Number=Sing	_	_	_	_
30	pathways	_	NOUN	_	Number=Plur	_	_	_	_
31	that	_	PRON	_	PronType=Rel	_	_	_	_
32	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	critical	_	ADJ	_	Degree=Pos	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	IgE	_	PROPN	_	Number=Sing	_	_	_	_
36	switching	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012079	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	delta	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	globin	_	ADJ	_	Degree=Pos	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	primary	_	ADJ	_	Degree=Pos	_	_	_	_
12	adult	_	NOUN	_	Number=Sing	_	_	_	_
13	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Restoration	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CCAAT	_	NOUN	_	Number=Sing	_	_	_	_
5	box	_	NOUN	_	Number=Sing	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	insertion	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
11	Kruppel	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	like	_	ADJ	_	Degree=Pos	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	binding	_	VERB	_	Number=Sing	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	delta	_	PROPN	_	Number=Sing	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	several	_	ADJ	_	Degree=Pos	_	_	_	_
29	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	lines	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	extended	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	using	_	VERB	_	VerbForm=Ger	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	novel	_	NOUN	_	Number=Sing	_	_	_	_
8	primary	_	ADJ	_	Degree=Pos	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	adult	_	NOUN	_	Number=Sing	_	_	_	_
11	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	hAEC	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	system	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
19	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
20	effects	_	NOUN	_	Number=Plur	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	late	_	ADJ	_	Degree=Pos	_	_	_	_
24	erythroblast	_	NOUN	_	Number=Sing	_	_	_	_
25	stage	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Restoration	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CCAAT	_	PROPN	_	Number=Sing	_	_	_	_
5	box	_	NOUN	_	Number=Sing	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	70	_	NUM	_	NumType=Card	_	_	_	_
9	bp	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	insertion	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	site	_	NOUN	_	Number=Sing	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	-	_	SYM	_	_	_	_	_	_
20	85	_	NUM	_	NumType=Card	_	_	_	_
21	bp	_	PROPN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	95	_	NUM	_	NumType=Card	_	_	_	_
25	bp	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	significantly	_	ADV	_	_	_	_	_	_
30	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	delta	_	NOUN	_	Number=Sing	_	_	_	_
32	globin	_	NOUN	_	Degree=Pos	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	hAEC	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	CCAAT	_	PROPN	_	Number=Sing	_	_	_	_
8	box	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	CCAAC	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	lack	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	EKLF	_	NOUN	_	Number=Sing	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	delta	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	globin	_	PROPN	_	Degree=Pos	_	_	_	_
24	contribute	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	low	_	ADJ	_	Degree=Pos	_	_	_	_
28	level	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	hAEC	_	NOUN	_	Number=Sing	_	_	_	_
34	model	_	NOUN	_	Number=Sing	_	_	_	_
35	as	_	ADV	_	_	_	_	_	_
36	well	_	ADV	_	Degree=Pos	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012083	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	functional	_	ADJ	_	Degree=Pos	_	_	_	_
5	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
6	D	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	all	_	DET	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	trans	_	NOUN	_	Number=Plur	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
14	acid	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	M2	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
24	blast	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Different	_	ADJ	_	Degree=Pos	_	_	_	_
2	types	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	acute	_	ADJ	_	Degree=Pos	_	_	_	_
5	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
6	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
7	blast	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vitro	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	all	_	DET	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	trans	_	NOUN	_	Number=Plur	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
21	acid	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
27	D3	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	VD	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	M0	_	NUM	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	M1	_	NUM	_	Number=Sing	_	_	_	_
4	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	agents	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	whereas	_	ADV	_	_	_	_	_	_

1	M3	_	NUM	_	NumType=Card	_	_	_	_
2	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	undergo	_	VERB	_	VerbForm=Inf	_	_	_	_
8	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
10	after	_	ADP	_	_	_	_	_	_
11	ATRA	_	NOUN	_	Number=Sing	_	_	_	_
12	treatment	_	NOUN	_	Number=Sing	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	VD	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	M2	_	NUM	_	NumType=Card	_	_	_	_
2	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
3	blast	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	behave	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	differently	_	ADV	_	_	_	_	_	_
7	because	_	SCONJ	_	_	_	_	_	_
8	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
9	undergo	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	inducers	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	gain	_	VERB	_	VerbForm=Inf	_	_	_	_
3	some	_	DET	_	_	_	_	_	_
4	insight	_	NOUN	_	Number=Sing	_	_	_	_
5	into	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	maturation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	M2	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	type	_	NOUN	_	Number=Sing	_	_	_	_
12	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
19	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
20	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
21	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	VD	_	PROPN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	spontaneous	_	ADJ	_	Degree=Pos	_	_	_	_

1	M2	_	NUM	_	NumType=Card	_	_	_	_
2	blast	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	as	_	ADV	_	_	_	_	_	_
5	well	_	ADV	_	Degree=Pos	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	Kasumi	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	acute	_	ADJ	_	Degree=Pos	_	_	_	_
15	myeloid	_	ADJ	_	Number=Sing	_	_	_	_
16	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
17	M2	_	NUM	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	type	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	line	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
6	as	_	ADV	_	_	_	_	_	_
7	well	_	ADV	_	Degree=Pos	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	VD	_	PROPN	_	Number=Sing	_	_	_	_
10	efficiently	_	ADV	_	_	_	_	_	_
11	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	abundance	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	VD	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	VDR	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	VDR	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	functionally	_	ADV	_	_	_	_	_	_
4	active	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	Kasumi	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	because	_	SCONJ	_	_	_	_	_	_
14	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
15	efficiently	_	ADV	_	_	_	_	_	_
16	heterodimerizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
19	X	_	PROPN	_	_	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	DR3	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	type	_	NOUN	_	Number=Sing	_	_	_	_
28	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
29	D	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
32	element	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	vitamin	_	ADJ	_	Number=Sing	_	_	_	_
41	D	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
44	element	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	reporter	_	NOUN	_	Number=Sing	_	_	_	_
48	gene	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	findings	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	VD	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
14	treatment	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	Kasumi	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
25	program	_	NOUN	_	Number=Sing	_	_	_	_
26	underlying	_	VERB	_	Degree=Pos	_	_	_	_
27	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
28	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
7	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	abundance	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	functional	_	ADJ	_	Degree=Pos	_	_	_	_
14	VDR	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	still	_	ADV	_	_	_	_	_	_
17	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
21	data	_	NOUN	_	Number=Sing	_	_	_	_
22	clearly	_	ADV	_	_	_	_	_	_
23	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	M2	_	PROPN	_	NumType=Card	_	_	_	_
27	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	context	_	NOUN	_	Number=Sing	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	only	_	ADV	_	_	_	_	_	_
32	permissive	_	ADJ	_	Degree=Pos	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
35	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012084	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	type	_	NOUN	_	Number=Sing	_	_	_	_
3	specificity	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	requirements	_	NOUN	_	Number=Plur	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	new	_	ADJ	_	Degree=Pos	_	_	_	_
24	method	_	NOUN	_	Number=Sing	_	_	_	_
25	using	_	VERB	_	VerbForm=Ger	_	_	_	_
26	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
27	mice	_	NOUN	_	Number=Plur	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	assay	_	VERB	_	VerbForm=Inf	_	_	_	_
30	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
31	activity	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	individual	_	ADJ	_	Degree=Pos	_	_	_	_
35	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
36	factor	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	T-cells	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	considered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	important	_	ADJ	_	Degree=Pos	_	_	_	_
22	regulator	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	early	_	ADJ	_	Degree=Pos	_	_	_	_
25	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	developed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	system	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	monitor	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	single	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	level	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	whole	_	ADJ	_	Degree=Pos	_	_	_	_
22	animals	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	system	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	use	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	oligomerized	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
11	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	motif	_	NOUN	_	Number=Sing	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	directs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	SV40	_	NOUN	_	Number=Sing	_	_	_	_
21	T-antigen	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
24	mice	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	report	_	NOUN	_	Number=Sing	_	_	_	_
3	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	demonstration	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	multimerized	_	ADJ	_	Degree=Pos	_	_	_	_
10	short	_	ADJ	_	Degree=Pos	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	motif	_	NOUN	_	Number=Sing	_	_	_	_
13	can	_	AUX	_	VerbForm=Fin	_	_	_	_
14	function	_	VERB	_	VerbForm=Inf	_	_	_	_
15	appropriately	_	ADV	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
18	mice	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	previously	_	ADV	_	_	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	confined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T-lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	upon	_	ADP	_	_	_	_	_	_
16	release	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
19	calcium	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	targeting	_	VERB	_	VerbForm=Ger	_	_	_	_
3	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1-	_	NUM	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
11	mice	_	NOUN	_	Number=Plur	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	discovered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	new	_	ADJ	_	Degree=Pos	_	_	_	_
15	sites	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Besides	_	ADP	_	_	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	T-lymphocytes	_	PROPN	_	Number=Sing	_	_	_	_
4	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	could	_	AUX	_	VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T-lymphocyte	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	depleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	spleen	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	B-	_	NOUN	_	_	_	_	_	_
21	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	requires	_	VERB	_	Number=Plur	_	_	_	_
24	agents	_	NOUN	_	Number=Plur	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	both	_	DET	_	_	_	_	_	_
27	release	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
29	calcium	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	protein	_	NOUN	_	Number=Sing	_	_	_	_
33	kinase	_	NOUN	_	Number=Sing	_	_	_	_
34	C	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	difference	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	time	_	NOUN	_	Number=Sing	_	_	_	_
6	course	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	appearance	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	between	_	ADP	_	_	_	_	_	_
15	T-lymphocytes	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	non-T	_	NOUN	_	Degree=Pos	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	revealed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	small	_	ADJ	_	Degree=Pos	_	_	_	_
8	population	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	dermis	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	some	_	DET	_	_	_	_	_	_
16	mice	_	NOUN	_	Number=Plur	_	_	_	_
17	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	developed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	skin	_	NOUN	_	Number=Sing	_	_	_	_
20	lesions	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	tissue	_	NOUN	_	Number=Sing	_	_	_	_
5	pattern	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	resembles	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	pattern	_	NOUN	_	Number=Sing	_	_	_	_
18	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	HIV	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	LTR	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	tat	_	NOUN	_	Number=Sing	_	_	_	_
25	transgenic	_	PROPN	_	Number=Sing	_	_	_	_
26	mice	_	NOUN	_	Number=Plur	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	Vogel	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	J.	_	PROPN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	Hinrichs	_	PROPN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	S.	_	PROPN	_	Number=Sing	_	_	_	_
35	H.	_	PROPN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	Reynolds	_	PROPN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	R.	_	PROPN	_	Number=Sing	_	_	_	_
40	K.	_	PROPN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	Luciw	_	PROPN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	P.	_	PROPN	_	Number=Sing	_	_	_	_
45	A.	_	PROPN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	Jay	_	PROPN	_	Number=Sing	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	G.	_	PROPN	_	Number=Sing	_	_	_	_
51	(	_	PUNCT	_	_	_	_	_	_
52	1988	_	NUM	_	NumType=Card	_	_	_	_
53	)	_	PUNCT	_	_	_	_	_	_
54	Nature	_	PROPN	_	Number=Sing	_	_	_	_
55	335	_	NUM	_	NumType=Card	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	606-611	_	NUM	_	NumType=Card	_	_	_	_
58	)	_	PUNCT	_	_	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	similarity	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	fact	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
17	functional	_	ADJ	_	Degree=Pos	_	_	_	_
18	sequences	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	HIV	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	LTR	_	PROPN	_	Number=Sing	_	_	_	_
23	suggest	_	VERB	_	VerbForm=Inf	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	role	_	NOUN	_	Number=Sing	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	dermal	_	ADJ	_	Degree=Pos	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	HIV	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	LTR	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012086	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
3	octamer	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	binding	_	VERB	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	s	_	X	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
3	genes	_	NOUN	_	Number=Plur	_	_	_	_
4	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	conserved	_	VERB	_	Degree=Pos	_	_	_	_
7	octanucleotide	_	NOUN	_	Number=Sing	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	ATGCAAAT	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	normal	_	ADJ	_	Degree=Pos	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Proteins	_	NOUN	_	Number=Plur	_	_	_	_
2	that	_	PRON	_	PronType=Rel	_	_	_	_
3	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	octamer	_	NOUN	_	Number=Sing	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	purified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	cDNAs	_	NOUN	_	Number=Plur	_	_	_	_
12	encoding	_	VERB	_	Number=Sing	_	_	_	_
13	octamer	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Some	_	DET	_	_	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	proteins	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	referred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	as	_	ADP	_	_	_	_	_	_
9	OTF	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	X	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	whereas	_	SCONJ	_	_	_	_	_	_
18	at	_	ADV	_	_	_	_	_	_
19	least	_	ADV	_	Degree=Sup	_	_	_	_
20	one	_	NUM	_	NumType=Card	_	_	_	_
21	other	_	ADJ	_	Degree=Pos	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	possibly	_	ADV	_	_	_	_	_	_
25	more	_	ADV	_	_	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	referred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	as	_	ADP	_	_	_	_	_	_
30	OTF	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	ubiquitously	_	ADV	_	_	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	all	_	DET	_	_	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	types	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	exact	_	ADJ	_	Degree=Pos	_	_	_	_
3	role	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	different	_	ADJ	_	Degree=Pos	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	directing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	tissue	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	pre-B	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	lines	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	extremely	_	ADV	_	_	_	_	_	_
13	low	_	ADJ	_	Degree=Pos	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	OTF	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	yet	_	CCONJ	_	_	_	_	_	_
20	still	_	ADV	_	_	_	_	_	_
21	express	_	ADJ	_	Degree=Pos	_	_	_	_
22	high	_	ADJ	_	Degree=Pos	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	steady	_	ADJ	_	Degree=Pos	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	state	_	NOUN	_	Number=Sing	_	_	_	_
28	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
29	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	chain	_	NOUN	_	Number=Sing	_	_	_	_
32	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	vivo	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	efficiently	_	ADV	_	_	_	_	_	_
37	transcribe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	vitro	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Addition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	highly	_	ADV	_	_	_	_	_	_
5	enriched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	preparation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	OTF	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	made	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	one	_	NUM	_	NumType=Card	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
16	pre	_	X	_	_	_	_	_	_
17	-B	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	specifically	_	ADV	_	_	_	_	_	_
24	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vitro	_	NOUN	_	Number=Sing	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	OFT	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	have	_	VERB	_	VerbForm=Inf	_	_	_	_
9	approximately	_	ADV	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	same	_	ADJ	_	Degree=Pos	_	_	_	_
12	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
13	ability	_	NOUN	_	Number=Sing	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	OTF	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	when	_	ADV	_	PronType=Int	_	_	_	_
19	normalized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	OTF	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	without	_	ADP	_	_	_	_	_	_
10	OTF	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	that	_	DET	_	_	_	_	_	_
23	OTF	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	alone	_	ADJ	_	_	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	B	_	NUM	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	specific	_	ADJ	_	Degree=Pos	_	_	_	_
37	regulation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012093	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	alpha	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Tocopheryl	_	PROPN	_	Number=Sing	_	_	_	_
4	succinate	_	NOUN	_	Number=Sing	_	_	_	_
5	inhibits	_	VERB	_	Number=Plur	_	_	_	_
6	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	endothelial	_	VERB	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	suppressing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	adherence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	endothelium	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	early	_	ADJ	_	Degree=Pos	_	_	_	_
11	event	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	atherogenesis	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	considered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	antiatherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
10	potential	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	effects	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	tocopherol	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	TCP	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	acetate	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	succinate	_	ADJ	_	Degree=Pos	_	_	_	_
28	esters	_	NOUN	_	Number=Plur	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
31	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	cytokine	_	VERB	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	human	_	ADJ	_	Degree=Pos	_	_	_	_
37	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
38	vein	_	NOUN	_	Number=Sing	_	_	_	_
39	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	HUVEC	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	TCP	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	tocopherol	_	NOUN	_	Number=Sing	_	_	_	_
11	acetate	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	TCP	_	NOUN	_	Number=Sing	_	_	_	_
14	acetate	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	tocopheryl	_	NOUN	_	Number=Sing	_	_	_	_
21	succinate	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	TCP	_	NOUN	_	Number=Sing	_	_	_	_
24	succinate	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	before	_	ADP	_	_	_	_	_	_
27	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	tumor	_	NOUN	_	Number=Sing	_	_	_	_
30	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	TNF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	;	_	PUNCT	_	_	_	_	_	_
39	10	_	NUM	_	NumType=Card	_	_	_	_
40	U/ml	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	6	_	NUM	_	NumType=Card	_	_	_	_
43	h	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	or	_	CCONJ	_	_	_	_	_	_
46	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	1	_	NUM	_	NumType=Card	_	_	_	_
49	beta	_	NOUN	_	Number=Sing	_	_	_	_
50	(	_	PUNCT	_	_	_	_	_	_
51	IL	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	1	_	NUM	_	NumType=Card	_	_	_	_
54	beta	_	NOUN	_	Number=Sing	_	_	_	_
55	;	_	PUNCT	_	_	_	_	_	_
56	10	_	NUM	_	NumType=Card	_	_	_	_
57	U/ml	_	NOUN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	6	_	NUM	_	NumType=Card	_	_	_	_
60	h	_	NOUN	_	_	_	_	_	_
61	)	_	PUNCT	_	_	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	Cytokine	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	surface	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
11	molecule	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	CD106	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	E-selectin	_	PROPN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	ELAM	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	CD62E	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	but	_	CCONJ	_	_	_	_	_	_
32	not	_	ADV	_	_	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
35	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
36	molecule	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	CD54	_	NOUN	_	Number=Sing	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
48	time	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	dose	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	dependently	_	ADV	_	_	_	_	_	_
54	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
55	by	_	ADP	_	_	_	_	_	_
56	TCP	_	NOUN	_	Number=Sing	_	_	_	_
57	succinate	_	NOUN	_	Number=Sing	_	_	_	_
58	but	_	CCONJ	_	_	_	_	_	_
59	not	_	ADV	_	_	_	_	_	_
60	by	_	ADP	_	_	_	_	_	_
61	TCP	_	NOUN	_	Number=Sing	_	_	_	_
62	or	_	CCONJ	_	_	_	_	_	_
63	TCP	_	NOUN	_	Number=Sing	_	_	_	_
64	acetate	_	NOUN	_	Number=Sing	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	TCP	_	NOUN	_	Number=Sing	_	_	_	_
2	succinate	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	200	_	NUM	_	NumType=Card	_	_	_	_
5	microM	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	24	_	NUM	_	NumType=Card	_	_	_	_
8	h	_	NOUN	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	E-selectin	_	NOUN	_	Degree=Pos	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	mean	_	NOUN	_	Number=Sing	_	_	_	_
24	fluorescence	_	NOUN	_	Number=Sing	_	_	_	_
25	intensity	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	151	_	NUM	_	NumType=Card	_	_	_	_
28	+/-	_	SYM	_	_	_	_	_	_
29	28	_	NUM	_	NumType=Card	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	12	_	NUM	_	NumType=Card	_	_	_	_
32	+/-	_	SYM	_	_	_	_	_	_
33	4	_	NUM	_	NumType=Card	_	_	_	_
34	channels	_	NOUN	_	Number=Plur	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	from	_	ADP	_	_	_	_	_	_
37	225	_	NUM	_	NumType=Card	_	_	_	_
38	+/-	_	SYM	_	_	_	_	_	_
39	38	_	NUM	_	NumType=Card	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	79	_	NUM	_	NumType=Card	_	_	_	_
42	+/-	_	SYM	_	_	_	_	_	_
43	21	_	NUM	_	NumType=Card	_	_	_	_
44	channels	_	NOUN	_	Number=Plur	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	respectively	_	ADV	_	_	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Succinate	_	PROPN	_	Number=Sing	_	_	_	_
2	alone	_	ADV	_	_	_	_	_	_
3	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	no	_	DET	_	_	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	Decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
3	molecule	_	NOUN	_	Degree=Pos	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	reduction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	TCP	_	NOUN	_	Number=Sing	_	_	_	_
2	succinate	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	20	_	NUM	_	NumType=Card	_	_	_	_
5	microM	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	72	_	NUM	_	NumType=Card	_	_	_	_
8	h	_	NOUN	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	ADV	_	_	_	_	_	_
13	TCP	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	200	_	NUM	_	NumType=Card	_	_	_	_
16	microM	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	72	_	NUM	_	NumType=Card	_	_	_	_
19	h	_	NOUN	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	U	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	SYM	_	_	_	_	_	_
25	937	_	NUM	_	NumType=Card	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	TNF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	10	_	NUM	_	NumType=Card	_	_	_	_
36	U/ml	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	6	_	NUM	_	NumType=Card	_	_	_	_
39	h	_	NOUN	_	_	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	HUVEC	_	PROPN	_	Number=Sing	_	_	_	_
42	by	_	ADP	_	_	_	_	_	_
43	30	_	NUM	_	NumType=Card	_	_	_	_
44	%	_	SYM	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	P	_	NOUN	_	Number=Sing	_	_	_	_
47	<	_	PUNCT	_	_	_	_	_	_
48	0.025	_	NUM	_	NumType=Card	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	to	_	ADP	_	_	_	_	_	_
52	IL	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	1	_	NUM	_	NumType=Card	_	_	_	_
55	beta-stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
56	HUVEC	_	PROPN	_	Number=Sing	_	_	_	_
57	by	_	ADP	_	_	_	_	_	_
58	56	_	NUM	_	NumType=Card	_	_	_	_
59	%	_	SYM	_	Number=Sing	_	_	_	_
60	(	_	PUNCT	_	_	_	_	_	_
61	P	_	NOUN	_	Number=Sing	_	_	_	_
62	<	_	PUNCT	_	_	_	_	_	_
63	0.010	_	NUM	_	NumType=Card	_	_	_	_
64	)	_	PUNCT	_	_	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	HUVEC	_	PROPN	_	Number=Sing	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	decrease	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	after	_	ADP	_	_	_	_	_	_
32	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	HUVEC	_	NOUN	_	Number=Sing	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	TCP	_	NOUN	_	Number=Sing	_	_	_	_
37	succinate	_	NOUN	_	Number=Sing	_	_	_	_
38	but	_	CCONJ	_	_	_	_	_	_
39	not	_	ADV	_	_	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	TCP	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	TCP	_	NOUN	_	Number=Sing	_	_	_	_
44	acetate	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	or	_	CCONJ	_	_	_	_	_	_
47	succinate	_	VERB	_	Number=Sing	_	_	_	_
48	alone	_	ADV	_	_	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
9	E	_	PROPN	_	Number=Sing	_	_	_	_
10	derivative	_	ADJ	_	Number=Sing	_	_	_	_
11	TCP	_	NOUN	_	Number=Sing	_	_	_	_
12	succinate	_	NOUN	_	Number=Sing	_	_	_	_
13	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	cytokine	_	VERB	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	by	_	SCONJ	_	_	_	_	_	_
24	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	further	_	ADV	_	Degree=Pos	_	_	_	_
34	emphasizing	_	VERB	_	VerbForm=Ger	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	antiatherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
37	potential	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	lipid	_	ADJ	_	Degree=Pos	_	_	_	_
40	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
41	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012098	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Lineage	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	stage	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	runt	_	NOUN	_	Number=Sing	_	_	_	_
10	box	_	NOUN	_	Number=Sing	_	_	_	_
11	polypeptides	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	primitive	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	definitive	_	ADJ	_	Degree=Pos	_	_	_	_
16	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Translocations	_	NOUN	_	Number=Plur	_	_	_	_
2	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	CBFA2	_	NOUN	_	Number=Sing	_	_	_	_
6	locus	_	NOUN	_	Number=Sing	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	originally	_	ADV	_	_	_	_	_	_
5	named	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	AML1	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	homologue	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	Drosophila	_	PROPN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	runt	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	_	_	_	_	_
18	controls	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	early	_	ADJ	_	Degree=Pos	_	_	_	_
20	events	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	fly	_	VERB	_	Number=Sing	_	_	_	_
23	embryogenesis	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	clarify	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
7	runt	_	NOUN	_	Number=Sing	_	_	_	_
8	products	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	normal	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
13	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	pattern	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	mouse	_	NOUN	_	Number=Sing	_	_	_	_
24	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
25	tissues	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	adult	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	during	_	ADP	_	_	_	_	_	_
31	ontogeny	_	NOUN	_	Number=Sing	_	_	_	_
32	using	_	VERB	_	VerbForm=Ger	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	anti-runt	_	NOUN	_	Number=Sing	_	_	_	_
35	box	_	NOUN	_	Number=Sing	_	_	_	_
36	antiserum	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	adult	_	NOUN	_	Number=Sing	_	_	_	_
4	bone	_	NOUN	_	Number=Sing	_	_	_	_
5	marrow	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	runt	_	NOUN	_	Number=Sing	_	_	_	_
12	polypeptides	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	SCONJ	_	_	_	_	_	_
14	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	B	_	NOUN	_	Degree=Pos	_	_	_	_
20	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Within	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
4	lineage	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	runt	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	clearly	_	ADV	_	_	_	_	_	_
12	present	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	early	_	ADJ	_	Degree=Pos	_	_	_	_
18	blood	_	NOUN	_	Number=Sing	_	_	_	_
19	islands	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	fetal	_	NOUN	_	Number=Sing	_	_	_	_
24	liver	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	absent	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	adult	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	Western	_	ADJ	_	Degree=Pos	_	_	_	_
5	blotting	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	fetal	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	adult	_	NOUN	_	Number=Sing	_	_	_	_
10	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
11	populations	_	NOUN	_	Number=Plur	_	_	_	_
12	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	several	_	ADJ	_	Degree=Pos	_	_	_	_
14	runt	_	NOUN	_	Number=Sing	_	_	_	_
15	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADV	_	_	_	_	_	_
2	least	_	ADV	_	Degree=Sup	_	_	_	_
3	one	_	NUM	_	NumType=Card	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
6	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	myeloid	_	VERB	_	Degree=Pos	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012099	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Some	_	DET	_	_	_	_	_	_
2	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
3	inhibit	_	VERB	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	co	_	X	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	ordinate	_	ADJ	_	Degree=Pos	_	_	_	_
10	fashion	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	tumor	_	NOUN	_	Number=Sing	_	_	_	_
16	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	beta	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	6	_	NUM	_	NumType=Card	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
32	blood	_	NOUN	_	Number=Sing	_	_	_	_
33	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Some	_	DET	_	_	_	_	_	_
2	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	including	_	VERB	_	VerbForm=Ger	_	_	_	_
5	butylated	_	ADJ	_	Number=Sing	_	_	_	_
6	hydroxyanisole	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	BHA	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	tetrahydropapaveroline	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	THP	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	nordihydroguiauretic	_	ADJ	_	Degree=Pos	_	_	_	_
17	acid	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	10,11	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dihydroxyaporphine	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	DHA	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	potent	_	ADJ	_	Degree=Pos	_	_	_	_
32	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	production	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	tumor	_	NOUN	_	Number=Sing	_	_	_	_
38	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
39	factor	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	TNF	_	PROPN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	alpha	_	PROPN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	IL	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	1	_	NUM	_	NumType=Card	_	_	_	_
49	beta	_	NOUN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	IL	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	6	_	NUM	_	NumType=Card	_	_	_	_
55	by	_	ADP	_	_	_	_	_	_
56	human	_	ADJ	_	Degree=Pos	_	_	_	_
57	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
58	blood	_	NOUN	_	Number=Sing	_	_	_	_
59	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
60	cells	_	NOUN	_	Number=Plur	_	_	_	_
61	(	_	PUNCT	_	_	_	_	_	_
62	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
63	)	_	PUNCT	_	_	_	_	_	_
64	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
65	by	_	ADP	_	_	_	_	_	_
66	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
67	(	_	PUNCT	_	_	_	_	_	_
68	LPS	_	NOUN	_	Number=Sing	_	_	_	_
69	)	_	PUNCT	_	_	_	_	_	_
70	(	_	PUNCT	_	_	_	_	_	_
71	IC50s	_	NOUN	_	Number=Plur	_	_	_	_
72	in	_	ADP	_	_	_	_	_	_
73	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
74	low	_	ADJ	_	Degree=Pos	_	_	_	_
75	micromolar	_	NOUN	_	Degree=Pos	_	_	_	_
76	range	_	NOUN	_	Number=Sing	_	_	_	_
77	)	_	PUNCT	_	_	_	_	_	_
78	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
4	production	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	selective	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	due	_	ADP	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	general	_	ADJ	_	Degree=Pos	_	_	_	_
13	effects	_	NOUN	_	Number=Plur	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
4	production	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	when	_	ADV	_	PronType=Int	_	_	_	_
11	other	_	ADJ	_	Degree=Pos	_	_	_	_
12	inducers	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	staphylococci	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	silica	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	zymosan	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Much	_	ADV	_	_	_	_	_	_
2	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
3	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	other	_	ADJ	_	Degree=Pos	_	_	_	_
6	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
7	--	_	PUNCT	_	_	_	_	_	_
8	including	_	VERB	_	VerbForm=Ger	_	_	_	_
9	ascorbic	_	ADJ	_	Degree=Pos	_	_	_	_
10	acid	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	trolox	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	tocopherol	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	butylated	_	ADJ	_	Degree=Pos	_	_	_	_
19	hydroxytoluene	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	5	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	lipoxygenase	_	NOUN	_	Number=Sing	_	_	_	_
26	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
27	zileuton	_	NOUN	_	Number=Sing	_	_	_	_
28	--	_	PUNCT	_	_	_	_	_	_
29	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	not	_	PART	_	_	_	_	_	_
31	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	production	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
36	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	active	_	ADJ	_	Degree=Pos	_	_	_	_
3	compounds	_	NOUN	_	Number=Plur	_	_	_	_
4	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	6	_	NUM	_	NumType=Card	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	showing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	selectivity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	effect	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
7	production	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	low	_	ADJ	_	Degree=Pos	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
16	messenger	_	NOUN	_	Number=Sing	_	_	_	_
17	RNAs	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	run	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	experiments	_	NOUN	_	Number=Plur	_	_	_	_
6	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	THP	_	DET	_	Number=Sing	_	_	_	_
9	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	beta	_	NOUN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	THP	_	NOUN	_	Number=Sing	_	_	_	_
2	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	concentration	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	AP	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	extracts	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
23	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	presence	_	NOUN	_	Number=Sing	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	absence	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	LPS	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	THP	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	DHA	_	PROPN	_	Number=Sing	_	_	_	_
4	markedly	_	ADV	_	_	_	_	_	_
5	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	TNF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	beta	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	circulation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	mice	_	NOUN	_	Number=Plur	_	_	_	_
22	following	_	VERB	_	VerbForm=Ger	_	_	_	_
23	LPS	_	NOUN	_	Number=Sing	_	_	_	_
24	injection	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
3	vary	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	widely	_	ADV	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	potency	_	NOUN	_	Number=Sing	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	pro-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Coordinate	_	ADJ	_	Degree=Pos	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	genes	_	NOUN	_	Number=Plur	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
11	could	_	AUX	_	VerbForm=Fin	_	_	_	_
12	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	strategy	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	therapy	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	diseases	_	NOUN	_	Number=Plur	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	septic	_	ADJ	_	Number=Sing	_	_	_	_
25	shock	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012103	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	prevented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
18	phospholipase	_	NOUN	_	Number=Sing	_	_	_	_
19	A2	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
5	induces	_	VERB	_	Number=Plur	_	_	_	_
6	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	85	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kDa	_	NOUN	_	Number=Sing	_	_	_	_
14	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
15	phospholipase	_	NOUN	_	Number=Sing	_	_	_	_
16	A2	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
3	releases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	arachidonic	_	NOUN	_	Degree=Pos	_	_	_	_
5	acid	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	lyso	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	phospholipids	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	membranes	_	NOUN	_	Number=Plur	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	metabolized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	eicosanoids	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	platelet	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	activating	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	lipid	_	ADJ	_	Degree=Pos	_	_	_	_
3	mediators	_	NOUN	_	Number=Plur	_	_	_	_
4	increase	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	function	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
19	phospholipase	_	NOUN	_	Number=Sing	_	_	_	_

1	A2	_	ADP	_	_	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	signal	_	NOUN	_	Number=Sing	_	_	_	_
4	transduction	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	previously	_	ADV	_	_	_	_	_	_
5	that	_	DET	_	_	_	_	_	_
6	trifluoromethylketone	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
10	phospholipase	_	NOUN	_	Number=Sing	_	_	_	_

1	A2	_	ADV	_	_	_	_	_	_
2	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1beta	_	NOUN	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	steady	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	state	_	NOUN	_	Number=Sing	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
19	blood	_	NOUN	_	Number=Sing	_	_	_	_
20	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	subcellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Int	_	_	_	_
12	trifluoromethylketones	_	NOUN	_	Number=Plur	_	_	_	_
13	interfere	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
5	reduced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	initial	_	ADJ	_	Degree=Pos	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1beta	_	NOUN	_	Number=Sing	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	rate	_	NOUN	_	Number=Sing	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	prevention	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	degradation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Consequently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	translocation	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	DNA	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Trifluoromethylketones	_	NOUN	_	Number=Plur	_	_	_	_
2	ameliorate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
4	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	vivo	_	NOUN	_	Number=Sing	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
5	potency	_	NOUN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	reside	_	VERB	_	VerbForm=Inf	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	retention	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
19	thereby	_	ADV	_	_	_	_	_	_
20	abrogating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	interleukin	_	ADJ	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1beta	_	NOUN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012104	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
2	activators	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	replication	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	lines	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	work	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	activators	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	LTR	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	PRON	_	_	_	_	_	_
7	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	replication	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
6	negative	_	ADJ	_	Degree=Pos	_	_	_	_
7	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	LIP	_	NOUN	_	Number=Sing	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	U1	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
26	proteins	_	NOUN	_	Number=Plur	_	_	_	_
27	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	provirus	_	NOUN	_	Number=Sing	_	_	_	_
31	induction	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	U1	_	PROPN	_	Number=Sing	_	_	_	_
2	lines	_	NOUN	_	Number=Plur	_	_	_	_
3	overexpressing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
5	activator	_	NOUN	_	Number=Sing	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	more	_	ADJ	_	_	_	_	_	_
13	viral	_	ADJ	_	Degree=Pos	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	particles	_	NOUN	_	Number=Plur	_	_	_	_
18	following	_	VERB	_	VerbForm=Ger	_	_	_	_
19	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	than	_	ADP	_	_	_	_	_	_
22	control	_	NOUN	_	Number=Sing	_	_	_	_
23	lines	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
28	proteins	_	NOUN	_	Number=Plur	_	_	_	_
29	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	limiting	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	virus	_	NOUN	_	Number=Sing	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	harboring	_	VERB	_	Number=Sing	_	_	_	_
5	mutations	_	NOUN	_	Number=Plur	_	_	_	_
6	within	_	ADP	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
9	sites	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	crippled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	ability	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	U937	_	PROPN	_	Number=Sing	_	_	_	_
19	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
25	sites	_	NOUN	_	Number=Plur	_	_	_	_
26	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	replication	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	regulators	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012109	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	BHRF1	_	PROPN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
7	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	type	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	development	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	resistance	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	host	_	VERB	_	VerbForm=Inf	_	_	_	_
7	defense	_	NOUN	_	Number=Sing	_	_	_	_
8	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
9	such	_	ADJ	_	Degree=Pos	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	tumor	_	NOUN	_	Number=Sing	_	_	_	_
12	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TNF	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	Fas	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
22	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	virus	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	may	_	AUX	_	VerbForm=Fin	_	_	_	_
31	be	_	AUX	_	VerbForm=Inf	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	critical	_	ADJ	_	Degree=Pos	_	_	_	_
34	component	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	development	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	disease	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	find	_	VERB	_	VerbForm=Inf	_	_	_	_
3	genes	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	protect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	cloning	_	ADJ	_	Number=Sing	_	_	_	_
15	strategy	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	BHRF1	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	Barr	_	PROPN	_	Number=Sing	_	_	_	_
24	virus	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	EBV	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	early	_	ADJ	_	Degree=Pos	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	cycle	_	NOUN	_	Number=Sing	_	_	_	_
33	protein	_	NOUN	_	Number=Sing	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	distant	_	ADJ	_	Degree=Pos	_	_	_	_
36	homology	_	NOUN	_	Number=Sing	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	2	_	NUM	_	NumType=Card	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	as	_	ADP	_	_	_	_	_	_
43	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	anti-apoptosis	_	ADJ	_	Degree=Pos	_	_	_	_
45	protein	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	BHRF1	_	PROPN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	MCF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Fas	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	conferred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	nearly	_	ADV	_	_	_	_	_	_
11	complete	_	ADJ	_	Degree=Pos	_	_	_	_
12	resistance	_	NOUN	_	Number=Sing	_	_	_	_
13	against	_	ADP	_	_	_	_	_	_
14	both	_	CCONJ	_	_	_	_	_	_
15	anti-Fas	_	ADJ	_	Degree=Pos	_	_	_	_
16	antibody	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	TNF	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
21	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	BHRF1	_	PROPN	_	Number=Sing	_	_	_	_
5	protected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	killing	_	NOUN	_	Number=Sing	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	protect	_	VERB	_	VerbForm=Inf	_	_	_	_
17	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
18	from	_	SCONJ	_	_	_	_	_	_
19	killing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	killer	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	BHRF1	_	PROPN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	protect	_	VERB	_	VerbForm=Inf	_	_	_	_
7	MCF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Fas	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	various	_	ADJ	_	Degree=Pos	_	_	_	_
16	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	identical	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	xL	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	action	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	BHRF1	_	PROPN	_	Number=Sing	_	_	_	_
9	resembled	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	xL	_	NOUN	_	Number=Sing	_	_	_	_
19	as	_	SCONJ	_	_	_	_	_	_
20	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
21	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	TNF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	anti-Fas	_	ADJ	_	Degree=Pos	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	two	_	NUM	_	NumType=Card	_	_	_	_
31	enzymes	_	NOUN	_	Number=Plur	_	_	_	_
32	participating	_	VERB	_	VerbForm=Ger	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
36	pathway	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
39	phospholipase	_	NOUN	_	Number=Sing	_	_	_	_

1	A2	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	caspase	_	NOUN	_	Number=Sing	_	_	_	_
4	-3	_	NUM	_	NumType=Card	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	CPP32	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	interfere	_	VERB	_	VerbForm=Inf	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	like	_	ADP	_	Degree=Pos	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	putative	_	ADJ	_	Degree=Pos	_	_	_	_
3	function	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	BHRF1	_	PROPN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	EBV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	epithelial	_	NOUN	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	be	_	VERB	_	VerbForm=Inf	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	protect	_	VERB	_	VerbForm=Inf	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	TNF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	anti-Fas	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	death	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	order	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	maximize	_	VERB	_	VerbForm=Inf	_	_	_	_
35	virus	_	NOUN	_	Number=Sing	_	_	_	_
36	production	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Surprisingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	neither	_	CCONJ	_	_	_	_	_	_
6	BHRF1	_	PROPN	_	Number=Sing	_	_	_	_
7	nor	_	CCONJ	_	_	_	_	_	_
8	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	line	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	BJAB	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	protected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	anti-Fas	_	NOUN	_	Degree=Pos	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
27	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
28	even	_	ADV	_	_	_	_	_	_
29	though	_	SCONJ	_	_	_	_	_	_
30	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
31	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	survival	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	serum	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	starved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	protective	_	ADJ	_	Degree=Pos	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	BHRF1	_	PROPN	_	Number=Sing	_	_	_	_
8	against	_	ADP	_	_	_	_	_	_
9	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
10	resembles	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	that	_	PRON	_	_	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	in	_	SCONJ	_	_	_	_	_	_
17	being	_	AUX	_	VerbForm=Ger	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	type	_	NOUN	_	Number=Sing	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
26	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012117	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	suppression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	programmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	death	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	B	_	ADJ	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	tissue	_	NOUN	_	Number=Sing	_	_	_	_
13	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	metalloproteinases	_	NOUN	_	Number=Plur	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_
19	Cellular	_	ADJ	_	Degree=Pos	_	_	_	_
20	pathways	_	NOUN	_	Number=Plur	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	induction	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	programmed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	death	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	PCD	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
32	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	little	_	ADV	_	Number=Sing	_	_	_	_
36	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	about	_	ADP	_	_	_	_	_	_
39	specific	_	ADJ	_	Degree=Pos	_	_	_	_
40	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
41	matrix	_	NOUN	_	Number=Sing	_	_	_	_
42	processes	_	NOUN	_	Number=Plur	_	_	_	_
43	that	_	PRON	_	PronType=Rel	_	_	_	_
44	may	_	AUX	_	VerbForm=Fin	_	_	_	_
45	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
46	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
47	along	_	ADP	_	_	_	_	_	_
48	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
49	pathways	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	series	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Burkitt	_	PROPN	_	Number=Sing	_	_	_	_
9	's	_	PART	_	_	_	_	_	_
10	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	BL	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	lines	_	NOUN	_	Number=Plur	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	assayed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	tissue	_	NOUN	_	Number=Sing	_	_	_	_
23	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	metalloproteinases	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	TIMP	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1.	_	NUM	_	NumType=Card	_	_	_	_
31	Results	_	NOUN	_	Number=Plur	_	_	_	_
32	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	that	_	SCONJ	_	_	_	_	_	_
34	TIMP	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1-	_	NUM	_	_	_	_	_	_
37	positive	_	ADJ	_	Degree=Pos	_	_	_	_
38	BL	_	NOUN	_	Number=Sing	_	_	_	_
39	lines	_	NOUN	_	Number=Plur	_	_	_	_
40	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
41	resistance	_	NOUN	_	Number=Sing	_	_	_	_
42	to	_	ADP	_	_	_	_	_	_
43	cold	_	ADJ	_	Degree=Pos	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	shock	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	recombinant	_	ADJ	_	Number=Sing	_	_	_	_
4	TIMP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	not	_	ADV	_	_	_	_	_	_
10	TIMP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	synthetic	_	ADJ	_	Degree=Pos	_	_	_	_
16	metalloproteinase	_	NOUN	_	Number=Sing	_	_	_	_
17	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	BB	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	94	_	NUM	_	NumType=Card	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	resistance	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	both	_	CCONJ	_	_	_	_	_	_
31	CD95	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	independent	_	ADJ	_	Degree=Pos	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	cold	_	ADJ	_	Degree=Pos	_	_	_	_
39	shock	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	serum	_	NOUN	_	Number=Sing	_	_	_	_
42	deprivation	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	gamma	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	radiation	_	NOUN	_	Number=Sing	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	pathways	_	NOUN	_	Number=Plur	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	TIMP	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	1	_	NUM	_	NumType=Card	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	negative	_	ADJ	_	Degree=Pos	_	_	_	_
56	BL	_	NOUN	_	Number=Sing	_	_	_	_
57	lines	_	NOUN	_	Number=Plur	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	TIMP	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	suppression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	PCD	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	due	_	ADP	_	_	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	metalloproteinase	_	NOUN	_	Number=Sing	_	_	_	_
12	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	reduction	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	alkylation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	TIMP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	abolish	_	VERB	_	VerbForm=Inf	_	_	_	_
26	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Retroviral	_	ADJ	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TIMP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	not	_	ADV	_	_	_	_	_	_
8	only	_	ADV	_	_	_	_	_	_
9	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	survival	_	NOUN	_	Number=Sing	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	continued	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	DNA	_	PROPN	_	Number=Sing	_	_	_	_
18	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	up	_	ADP	_	_	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	5	_	NUM	_	NumType=Card	_	_	_	_
23	d	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	absence	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	serum	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	while	_	SCONJ	_	_	_	_	_	_
31	controls	_	NOUN	_	Number=Plur	_	_	_	_
32	underwent	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	resistance	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	reversed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	anti-TIMP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	TIMP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	active	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
23	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	TIMP	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	XL	_	PROPN	_	Number=Sing	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	as	_	ADV	_	_	_	_	_	_
19	well	_	ADV	_	Degree=Pos	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	NF	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	as	_	ADP	_	_	_	_	_	_
27	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	controls	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TIMP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	suppresses	_	NOUN	_	Number=Plur	_	_	_	_
9	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	B	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	novel	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	TIMP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	tissue	_	NOUN	_	Number=Sing	_	_	_	_
24	homeostasis	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012126	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cooperation	_	NOUN	_	Number=Sing	_	_	_	_
2	between	_	ADP	_	_	_	_	_	_
3	core	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	elements	_	NOUN	_	Number=Plur	_	_	_	_
10	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	tissue	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Tissue	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	3	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	via	_	ADP	_	_	_	_	_	_
17	cis	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	elements	_	NOUN	_	Number=Plur	_	_	_	_
21	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	within	_	ADP	_	_	_	_	_	_
23	315	_	NUM	_	NumType=Card	_	_	_	_
24	base	_	NOUN	_	Number=Sing	_	_	_	_
25	pairs	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	start	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	achieved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	part	_	NOUN	_	Number=Sing	_	_	_	_
6	through	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	positive	_	ADJ	_	Degree=Pos	_	_	_	_
9	activities	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	AP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	Elf	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	sites	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	3	_	NUM	_	NumType=Card	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	contribution	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	other	_	ADJ	_	Degree=Pos	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	assessed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	transient	_	ADJ	_	Degree=Pos	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	assay	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	3	_	NUM	_	NumType=Card	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	constructs	_	NOUN	_	Number=Plur	_	_	_	_
26	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	focusing	_	VERB	_	VerbForm=Ger	_	_	_	_
33	initially	_	ADV	_	_	_	_	_	_
34	on	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	core	_	NOUN	_	Number=Sing	_	_	_	_
37	binding	_	NOUN	_	Number=Sing	_	_	_	_
38	factor	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	CBF	_	PROPN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	site	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	which	_	PRON	_	PronType=Rel	_	_	_	_
45	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
46	footprinted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	vivo	_	NOUN	_	Number=Sing	_	_	_	_
49	upon	_	ADP	_	_	_	_	_	_
50	T	_	PROPN	_	Number=Sing	_	_	_	_
51	cell	_	NOUN	_	Number=Sing	_	_	_	_
52	activation	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Activity	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CBF	_	PROPN	_	Number=Sing	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	critically	_	ADV	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
15	activator	_	NOUN	_	Number=Sing	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	Act	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	Act	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	CBF	_	NOUN	_	Number=Sing	_	_	_	_
8	sites	_	NOUN	_	Number=Plur	_	_	_	_
9	form	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	functional	_	ADJ	_	Degree=Pos	_	_	_	_
12	unit	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	AC	_	NOUN	_	Number=Sing	_	_	_	_
15	unit	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	dual	_	ADJ	_	Degree=Pos	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	AC	_	NOUN	_	Number=Sing	_	_	_	_
3	unit	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
8	basal	_	ADJ	_	Degree=Pos	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	promoters	_	NOUN	_	Number=Plur	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	further	_	ADV	_	_	_	_	_	_
5	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	already	_	ADV	_	_	_	_	_	_
6	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	NIP	_	PROPN	_	Number=Sing	_	_	_	_
8	repressor	_	NOUN	_	Number=Sing	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	evidence	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	presented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
17	repressor	_	NOUN	_	Number=Sing	_	_	_	_
18	region	_	NOUN	_	Number=Sing	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	restricts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	promoter	_	NOUN	_	Degree=Pos	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	positive	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	mapped	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	3	_	NUM	_	NumType=Card	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	between	_	ADP	_	_	_	_	_	_
18	nucleotide	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	180	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	-	_	SYM	_	_	_	_	_	_
23	210	_	NUM	_	NumType=Card	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	T	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	results	_	NOUN	_	Number=Plur	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	T	_	DET	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	specified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	single	_	ADJ	_	Degree=Pos	_	_	_	_
22	tissue	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	element	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	instead	_	ADV	_	_	_	_	_	_
29	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
31	interacting	_	NOUN	_	VerbForm=Ger	_	_	_	_
32	elements	_	NOUN	_	Number=Plur	_	_	_	_
33	that	_	PRON	_	PronType=Rel	_	_	_	_
34	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	both	_	DET	_	_	_	_	_	_
36	specific	_	ADJ	_	Degree=Pos	_	_	_	_
37	positive	_	ADJ	_	Degree=Pos	_	_	_	_
38	regulation	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	T	_	PROPN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	specific	_	ADJ	_	Degree=Pos	_	_	_	_
44	negative	_	ADJ	_	Degree=Pos	_	_	_	_
45	regulation	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012127	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Relief	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cyclin	_	NOUN	_	Number=Sing	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	during	_	ADP	_	_	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	via	_	ADP	_	_	_	_	_	_
13	CD2	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	CD28	_	PROPN	_	Number=Sing	_	_	_	_
16	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
17	molecules	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Cyclin	_	PROPN	_	Number=Sing	_	_	_	_
2	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	cycle	_	NOUN	_	Number=Sing	_	_	_	_
7	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
13	signals	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	underlined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	normal	_	ADJ	_	Degree=Pos	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	analysed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	vivo	_	NOUN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	DNA	_	NOUN	_	Number=Sing	_	_	_	_
22	interactions	_	NOUN	_	Number=Plur	_	_	_	_
23	at	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	Cyclin	_	PROPN	_	Number=Sing	_	_	_	_
26	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	locus	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	primary	_	ADJ	_	Degree=Pos	_	_	_	_
30	T	_	NOUN	_	Number=Sing	_	_	_	_
31	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	T	_	NOUN	_	Number=Sing	_	_	_	_
5	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	combination	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
11	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
12	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	CD2	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	CD28	_	PROPN	_	Number=Sing	_	_	_	_
17	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
18	molecules	_	NOUN	_	Number=Plur	_	_	_	_
19	gives	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	rise	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	long	_	ADJ	_	Degree=Pos	_	_	_	_
24	lasting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	absence	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	accessory	_	ADJ	_	Degree=Pos	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Cyclin	_	PROPN	_	Number=Sing	_	_	_	_
2	A	_	PROPN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	after	_	ADP	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	days	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	anti	_	PROPN	_	_	_	_	_	_
12	CD2	_	PROPN	_	Number=Sing	_	_	_	_
13	+	_	SYM	_	_	_	_	_	_
14	CD28	_	PROPN	_	Number=Sing	_	_	_	_
15	whereas	_	SCONJ	_	_	_	_	_	_
16	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	anti	_	X	_	_	_	_	_	_
19	CD2	_	PROPN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	anti	_	PROPN	_	_	_	_	_	_
22	CD28	_	PROPN	_	Number=Sing	_	_	_	_
23	alone	_	ADV	_	_	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	effective	_	ADJ	_	Degree=Pos	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	PROPN	_	Number=Sing	_	_	_	_
3	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
4	DMS	_	PROPN	_	Number=Sing	_	_	_	_
5	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
6	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	upstream	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	major	_	ADJ	_	Degree=Pos	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	initiation	_	NOUN	_	Number=Sing	_	_	_	_
13	sites	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	presence	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	at	_	ADV	_	_	_	_	_	_
19	least	_	ADV	_	Degree=Sup	_	_	_	_
20	three	_	NUM	_	NumType=Card	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	sites	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	two	_	NUM	_	NumType=Card	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	constitutively	_	ADV	_	_	_	_	_	_
30	occupied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vitro	_	NOUN	_	Number=Sing	_	_	_	_
5	respectively	_	ADV	_	_	_	_	_	_
6	ATF	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Y	_	PROPN	_	Number=Sing	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	third	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	site	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	occupied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	quiescent	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	anti	_	X	_	_	_	_	_	_
15	CD2	_	PROPN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	anti	_	PROPN	_	_	_	_	_	_
18	CD28	_	PROPN	_	Number=Sing	_	_	_	_
19	alone	_	ADV	_	_	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
3	combination	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	anti	_	PROPN	_	_	_	_	_	_
6	CD2	_	PROPN	_	Number=Sing	_	_	_	_
7	+	_	SYM	_	_	_	_	_	_
8	anti	_	PROPN	_	_	_	_	_	_
9	CD28	_	PROPN	_	Number=Sing	_	_	_	_
10	released	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	footprint	_	NOUN	_	Number=Sing	_	_	_	_
13	as	_	SCONJ	_	_	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	committed	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	theses	_	NOUN	_	Number=Plur|PronType=Dem	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	extracts	_	NOUN	_	Number=Plur	_	_	_	_
8	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	quiescent	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	complex	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
18	element	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	whereas	_	SCONJ	_	_	_	_	_	_
21	extracts	_	NOUN	_	Number=Plur	_	_	_	_
22	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	anti	_	NOUN	_	_	_	_	_	_
28	CD2	_	NOUN	_	Number=Sing	_	_	_	_
29	+	_	SYM	_	_	_	_	_	_
30	anti	_	PROPN	_	_	_	_	_	_
31	CD28	_	PROPN	_	Number=Sing	_	_	_	_
32	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	do	_	VERB	_	VerbForm=Inf	_	_	_	_
35	so	_	ADV	_	_	_	_	_	_
36	after	_	SCONJ	_	_	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	entered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
41	state	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012134	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_

1	Ig	_	ADJ	_	_	_	_	_	_
2	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
3	chain	_	NOUN	_	Number=Sing	_	_	_	_
4	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
5	only	_	ADV	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	ubiquitously	_	ADV	_	_	_	_	_	_
11	active	_	ADJ	_	Degree=Pos	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
3	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
4	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
8	intron	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
12	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
13	chain	_	NOUN	_	Number=Sing	_	_	_	_
14	constant	_	ADJ	_	Degree=Pos	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	major	_	ADJ	_	Degree=Pos	_	_	_	_
19	determinant	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	B	_	NOUN	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
29	genes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Like	_	ADP	_	_	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	Ig	_	PROPN	_	Number=Sing	_	_	_	_
7	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
8	chain	_	NOUN	_	Number=Sing	_	_	_	_
9	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
10	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	several	_	ADJ	_	Degree=Pos	_	_	_	_
12	short	_	ADJ	_	Degree=Pos	_	_	_	_
13	sequence	_	NOUN	_	Number=Sing	_	_	_	_
14	motifs	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	factors	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Each	_	DET	_	_	_	_	_	_
2	binding	_	VERB	_	Number=Sing	_	_	_	_
3	site	_	NOUN	_	Number=Sing	_	_	_	_
4	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	overall	_	ADJ	_	Degree=Pos	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	however	_	ADV	_	_	_	_	_	_
14	no	_	DET	_	_	_	_	_	_
15	single	_	ADJ	_	Degree=Pos	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	absolutely	_	ADV	_	_	_	_	_	_
19	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	better	_	ADJ	_	Degree=Cmp	_	_	_	_
4	understanding	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Ig	_	PROPN	_	Number=Sing	_	_	_	_
8	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
9	chain	_	NOUN	_	Number=Sing	_	_	_	_
10	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
11	components	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	individual	_	ADJ	_	Degree=Pos	_	_	_	_
19	sequence	_	NOUN	_	Number=Sing	_	_	_	_
20	elements	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	E3	_	PROPN	_	Number=Sing	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	motif	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	CATGTGGC	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	active	_	ADJ	_	Degree=Pos	_	_	_	_
7	form	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	B	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	non-B	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	where	_	ADV	_	PronType=Rel	_	_	_	_
17	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
18	can	_	AUX	_	VerbForm=Fin	_	_	_	_
19	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	vitro	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vivo	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	despite	_	ADP	_	_	_	_	_	_
4	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
5	ability	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	transfected	_	VERB	_	Degree=Pos	_	_	_	_
12	reporter	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	apparently	_	ADV	_	_	_	_	_	_
19	unable	_	ADJ	_	Degree=Pos	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_

1	Ig	_	ADJ	_	_	_	_	_	_
2	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
3	chain	_	NOUN	_	Number=Sing	_	_	_	_
4	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	non-lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	previous	_	ADJ	_	Degree=Pos	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	others	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	characteristic	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vivo	_	ADJ	_	Number=Sing	_	_	_	_
11	footprint	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	NF	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	muE3	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	B	_	ADJ	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	non	_	X	_	_	_	_	_	_
30	-B	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	From	_	ADP	_	_	_	_	_	_
2	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	other	_	ADJ	_	Degree=Pos	_	_	_	_
5	findings	_	NOUN	_	Number=Plur	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	picture	_	NOUN	_	Number=Sing	_	_	_	_
8	emerges	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	there	_	PRON	_	_	_	_	_	_
11	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	at	_	ADV	_	_	_	_	_	_
13	least	_	ADV	_	Degree=Sup	_	_	_	_
14	three	_	NUM	_	NumType=Card	_	_	_	_
15	categories	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	:	_	PUNCT	_	_	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	a	_	X	_	_	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	specific	_	ADJ	_	Degree=Pos	_	_	_	_
36	factors	_	NOUN	_	Number=Plur	_	_	_	_
37	such	_	ADJ	_	Degree=Pos	_	_	_	_
38	as	_	ADP	_	_	_	_	_	_
39	Oct	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2A	_	PROPN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	Oct	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	2B	_	NOUN	_	Number=Sing	_	_	_	_
46	that	_	PRON	_	PronType=Rel	_	_	_	_
47	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
48	not	_	PART	_	_	_	_	_	_
49	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	most	_	ADJ	_	Degree=Sup	_	_	_	_
52	other	_	ADJ	_	Degree=Pos	_	_	_	_
53	cell	_	NOUN	_	Number=Sing	_	_	_	_
54	types	_	NOUN	_	Number=Plur	_	_	_	_
55	:	_	PUNCT	_	_	_	_	_	_
56	(	_	PUNCT	_	_	_	_	_	_
57	b	_	X	_	_	_	_	_	_
58	)	_	PUNCT	_	_	_	_	_	_
59	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
60	factors	_	NOUN	_	Number=Plur	_	_	_	_
61	such	_	ADJ	_	Degree=Pos	_	_	_	_
62	as	_	ADP	_	_	_	_	_	_
63	NF	_	PROPN	_	Number=Sing	_	_	_	_
64	-	_	PUNCT	_	_	_	_	_	_
65	kappa	_	NOUN	_	Number=Sing	_	_	_	_
66	B	_	NOUN	_	Number=Sing	_	_	_	_
67	that	_	PRON	_	PronType=Rel	_	_	_	_
68	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
69	constitutively	_	ADV	_	_	_	_	_	_
70	active	_	ADJ	_	Degree=Pos	_	_	_	_
71	in	_	ADP	_	_	_	_	_	_
72	B	_	ADJ	_	Number=Sing	_	_	_	_
73	cells	_	NOUN	_	Number=Plur	_	_	_	_
74	but	_	CCONJ	_	_	_	_	_	_
75	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
76	sequestered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
77	in	_	ADP	_	_	_	_	_	_
78	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
79	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
80	form	_	NOUN	_	Number=Sing	_	_	_	_
81	in	_	ADP	_	_	_	_	_	_
82	other	_	ADJ	_	Degree=Pos	_	_	_	_
83	cells	_	NOUN	_	Number=Plur	_	_	_	_
84	;	_	PUNCT	_	_	_	_	_	_
85	(	_	PUNCT	_	_	_	_	_	_
86	c	_	NOUN	_	_	_	_	_	_
87	)	_	PUNCT	_	_	_	_	_	_
88	ubiquitously	_	ADV	_	_	_	_	_	_
89	active	_	ADJ	_	Degree=Pos	_	_	_	_
90	factors	_	NOUN	_	Number=Plur	_	_	_	_
91	,	_	PUNCT	_	_	_	_	_	_
92	exemplified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
93	by	_	ADP	_	_	_	_	_	_
94	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
95	one	_	NUM	_	NumType=Card	_	_	_	_
96	binding	_	NOUN	_	Number=Sing	_	_	_	_
97	to	_	ADP	_	_	_	_	_	_
98	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
99	E3	_	NUM	_	Number=Sing	_	_	_	_
100	sequence	_	NOUN	_	Number=Sing	_	_	_	_
101	motif	_	NOUN	_	Number=Sing	_	_	_	_
102	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	present	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	active	_	ADJ	_	Degree=Pos	_	_	_	_
8	form	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	variety	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	types	_	NOUN	_	Number=Plur	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	apparently	_	ADV	_	_	_	_	_	_
18	unable	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_

1	Ig	_	ADJ	_	_	_	_	_	_
2	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
3	chain	_	NOUN	_	Number=Sing	_	_	_	_
4	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	non-B	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	perhaps	_	ADV	_	_	_	_	_	_
10	due	_	ADP	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	non-permissive	_	ADJ	_	Degree=Pos	_	_	_	_
14	chromatin	_	NOUN	_	Degree=Pos	_	_	_	_
15	structure	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	Ig	_	PROPN	_	Number=Sing	_	_	_	_
19	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
20	chain	_	NOUN	_	Number=Sing	_	_	_	_
21	locus	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012135	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Direct	_	ADJ	_	Degree=Pos	_	_	_	_
2	interaction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	GATA	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	:	_	PUNCT	_	_	_	_	_	_
13	functional	_	ADJ	_	Degree=Pos	_	_	_	_
14	antagonism	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Malignant	_	ADJ	_	Degree=Pos	_	_	_	_
2	transformation	_	NOUN	_	Number=Sing	_	_	_	_
3	usually	_	ADV	_	_	_	_	_	_
4	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	precise	_	ADJ	_	Degree=Pos	_	_	_	_
11	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
12	involved	_	VERB	_	Degree=Pos	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_

1	Ets	_	NOUN	_	Number=Sing	_	_	_	_
2	family	_	NOUN	_	Number=Sing	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	development	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	some	_	DET	_	_	_	_	_	_
12	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
15	lineages	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	PU.	_	NOUN	_	Number=Sing	_	_	_	_
2	1	_	NUM	_	NumType=Card	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	act	_	VERB	_	VerbForm=Inf	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
16	precursors	_	NOUN	_	Number=Plur	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
19	insertion	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	transgenesis	_	NOUN	_	Number=Sing	_	_	_	_
22	causes	_	VERB	_	Number=Plur	_	_	_	_
23	erythroleukemias	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	mice	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Restoration	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
4	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	mouse	_	NOUN	_	Number=Sing	_	_	_	_
8	erythroleukemia	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	MEL	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	decline	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	level	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
25	can	_	AUX	_	VerbForm=Fin	_	_	_	_
26	block	_	VERB	_	VerbForm=Inf	_	_	_	_
27	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
28	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	investigate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
9	interferes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
5	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	directly	_	ADV	_	_	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	GATA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	zinc	_	NOUN	_	Number=Sing	_	_	_	_
14	finger	_	NOUN	_	Number=Sing	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
20	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Interaction	_	NOUN	_	Number=Sing	_	_	_	_
2	between	_	ADP	_	_	_	_	_	_
3	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	GATA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	intact	_	VERB	_	Degree=Pos	_	_	_	_
10	DNA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	domains	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	both	_	DET	_	_	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
2	represses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	GATA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1-	_	NUM	_	_	_	_	_	_
6	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
7	domains	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	repression	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	both	_	DET	_	_	_	_	_	_
16	domains	_	NOUN	_	Number=Plur	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	also	_	ADV	_	_	_	_	_	_
19	needed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	block	_	VERB	_	VerbForm=Inf	_	_	_	_
22	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	MEL	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	Xenopus	_	PROPN	_	Number=Sing	_	_	_	_
11	embryos	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	block	_	VERB	_	VerbForm=Inf	_	_	_	_
16	erythropoiesis	_	NOUN	_	Number=Sing	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	development	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	introduction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
6	GATA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	MEL	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	Xenopus	_	NOUN	_	Number=Sing	_	_	_	_
15	embryos	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	explants	_	NOUN	_	Number=Plur	_	_	_	_
18	relieves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	block	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	erythroid	_	VERB	_	Degree=Pos	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	imposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	stoichiometry	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	directly	_	ADV	_	_	_	_	_	_
9	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	opposing	_	ADJ	_	VerbForm=Ger	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
18	determinant	_	NOUN	_	Number=Sing	_	_	_	_
19	governing	_	NOUN	_	Number=Sing	_	_	_	_
20	processes	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	normal	_	ADJ	_	Degree=Pos	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	malignant	_	ADJ	_	Degree=Pos	_	_	_	_
26	transformation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012137	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
4	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
5	binding	_	VERB	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	CD40	_	PROPN	_	Number=Sing	_	_	_	_
9	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
10	domain	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	signal	_	NOUN	_	Number=Sing	_	_	_	_
5	transducing	_	NOUN	_	Number=Sing	_	_	_	_
6	adaptor	_	NOUN	_	Number=Sing	_	_	_	_
7	molecule	_	NOUN	_	Number=Sing	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	CD40	_	NOUN	_	Number=Sing	_	_	_	_
13	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
14	domain	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	phosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	predominantly	_	ADV	_	_	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	serine	_	NOUN	_	Number=Sing	_	_	_	_
12	residues	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	when	_	ADV	_	PronType=Int	_	_	_	_
15	transiently	_	ADV	_	_	_	_	_	_
16	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	293	_	NUM	_	NumType=Card	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
3	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	related	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	signaling	_	NOUN	_	Number=Sing	_	_	_	_
10	events	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
16	under	_	ADP	_	_	_	_	_	_
17	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
18	circumstances	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	since	_	SCONJ	_	_	_	_	_	_
21	two	_	NUM	_	NumType=Card	_	_	_	_
22	nonfunctional	_	ADJ	_	Degree=Pos	_	_	_	_
23	mutants	_	NOUN	_	Number=Plur	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	significantly	_	ADV	_	_	_	_	_	_
30	less	_	ADJ	_	Degree=Cmp	_	_	_	_
31	than	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	wild	_	NOUN	_	Degree=Pos	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	type	_	NOUN	_	Number=Sing	_	_	_	_
36	protein	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	status	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
8	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	significant	_	ADJ	_	Degree=Pos	_	_	_	_
10	effects	_	NOUN	_	Number=Plur	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	ability	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	CD40	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	as	_	SCONJ	_	_	_	_	_	_
23	evidenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
26	observations	_	NOUN	_	Number=Plur	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	CD40	_	PROPN	_	Number=Sing	_	_	_	_
30	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
31	domain	_	NOUN	_	Number=Sing	_	_	_	_
32	interacted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	preferentially	_	ADV	_	_	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	underphosphorylated	_	ADJ	_	Degree=Pos	_	_	_	_
36	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	that	_	DET	_	_	_	_	_	_
39	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
40	treatment	_	NOUN	_	Number=Sing	_	_	_	_
41	significantly	_	ADV	_	_	_	_	_	_
42	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	binding	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	TRAF2	_	NOUN	_	Number=Sing	_	_	_	_
47	to	_	ADP	_	_	_	_	_	_
48	CD40	_	PROPN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	TRAF2	_	PROPN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	likely	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	play	_	VERB	_	VerbForm=Inf	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	important	_	ADJ	_	Degree=Pos	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	SCONJ	_	_	_	_	_	_
19	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	signaling	_	VERB	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	virtue	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	ability	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	CD40	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	TRAF2	_	PROPN	_	Number=Sing	_	_	_	_
32	interaction	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1999	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012151	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
2	pathways	_	NOUN	_	Number=Plur	_	_	_	_
3	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	TNF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	families	_	NOUN	_	Number=Plur	_	_	_	_
13	target	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	common	_	ADJ	_	Degree=Pos	_	_	_	_
16	cis	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	element	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IFN	_	PROPN	_	Number=Sing	_	_	_	_
22	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	CD40	_	PROPN	_	Number=Sing	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	B	_	ADJ	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	strongly	_	ADV	_	_	_	_	_	_
8	influenced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	presence	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	basis	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	interplay	_	NOUN	_	Number=Sing	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
12	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	clearly	_	ADV	_	_	_	_	_	_
16	delineated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	IFN	_	PROPN	_	Number=Sing	_	_	_	_
2	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	IRF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	either	_	CCONJ	_	_	_	_	_	_
17	CD40	_	NOUN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	different	_	ADJ	_	Degree=Pos	_	_	_	_
7	sets	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	signals	_	NOUN	_	Number=Plur	_	_	_	_
10	target	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	common	_	ADJ	_	Degree=Pos	_	_	_	_
13	cis	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	IRF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	gamma	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	GAS	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Targeting	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	IRF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	GAS	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	confined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	via	_	ADP	_	_	_	_	_	_
14	CD40	_	PROPN	_	Number=Sing	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	extends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	mimic	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	CD40	_	NOUN	_	Number=Sing	_	_	_	_
24	signaling	_	VERB	_	Number=Sing	_	_	_	_
25	cascade	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	like	_	ADP	_	_	_	_	_	_
28	TNF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	alpha	_	PROPN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	EBV	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	STATs	_	NOUN	_	Number=Plur	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	IRF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	GAS	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	complex	_	NOUN	_	Number=Sing	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	CD40	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	TNF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	EBV	_	PROPN	_	Number=Sing	_	_	_	_
28	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	Rel	_	NOUN	_	Number=Sing	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	specifically	_	ADV	_	_	_	_	_	_
33	p50	_	NUM	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	p65	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	system	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	simultaneous	_	ADJ	_	Degree=Pos	_	_	_	_
6	exposure	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	CD40L	_	PROPN	_	Number=Sing	_	_	_	_
9	together	_	ADV	_	_	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	either	_	CCONJ	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	IFN	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	gamma	_	NOUN	_	Number=Sing	_	_	_	_
19	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	novel	_	NOUN	_	Number=Sing	_	_	_	_
27	Rel	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	STAT	_	NOUN	_	Number=Sing	_	_	_	_
30	complexes	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Given	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	importance	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	IRF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	variety	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	biologic	_	ADJ	_	Degree=Pos	_	_	_	_
13	functions	_	NOUN	_	Number=Plur	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
20	findings	_	NOUN	_	Number=Plur	_	_	_	_
21	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	notion	_	NOUN	_	Number=Sing	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	modulation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	IRF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	levels	_	NOUN	_	Number=Plur	_	_	_	_
31	may	_	AUX	_	VerbForm=Fin	_	_	_	_
32	be	_	AUX	_	VerbForm=Inf	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	critical	_	ADJ	_	Degree=Pos	_	_	_	_
35	control	_	NOUN	_	Number=Sing	_	_	_	_
36	point	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	B	_	ADJ	_	Number=Sing	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012160	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Signal	_	ADJ	_	Number=Sing	_	_	_	_
2	transduction	_	NOUN	_	Number=Sing	_	_	_	_
3	pathways	_	NOUN	_	Number=Plur	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	following	_	VERB	_	VerbForm=Ger	_	_	_	_
9	infection	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	Chlamydia	_	PROPN	_	Number=Sing	_	_	_	_
12	pneumoniae	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Chlamydia	_	PROPN	_	Number=Sing	_	_	_	_
2	pneumoniae	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	respiratory	_	ADJ	_	Degree=Pos	_	_	_	_
7	pathogen	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
4	presence	_	NOUN	_	Number=Sing	_	_	_	_
5	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	atherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
10	lesions	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	characterized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	C.	_	PROPN	_	Number=Sing	_	_	_	_
8	pneumoniae	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
22	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
23	molecules	_	NOUN	_	Number=Plur	_	_	_	_
24	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
27	rolling	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	transmigration	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	mAbs	_	NOUN	_	Number=Plur	_	_	_	_
7	against	_	ADP	_	_	_	_	_	_
8	endothelial	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
13	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
14	molecules	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	beta1	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	beta2	_	NOUN	_	Number=Sing	_	_	_	_
19	integrins	_	NOUN	_	Number=Plur	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	different	_	ADJ	_	Degree=Pos	_	_	_	_
6	signal	_	NOUN	_	Number=Sing	_	_	_	_
7	transduction	_	NOUN	_	Number=Sing	_	_	_	_
8	pathways	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	C.	_	PROPN	_	Number=Sing	_	_	_	_
11	pneumoniae	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	:	_	PUNCT	_	_	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
21	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	up	_	ADP	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	regulation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	p42/p44	_	NUM	_	Number=Sing	_	_	_	_
29	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	protein	_	NOUN	_	Number=Sing	_	_	_	_
33	kinase	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	/	_	PUNCT	_	_	_	_	_	_
41	translocation	_	NOUN	_	Number=Sing	_	_	_	_
42	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
43	within	_	ADP	_	_	_	_	_	_
44	10	_	NUM	_	NumType=Card	_	_	_	_
45	-	_	SYM	_	_	_	_	_	_
46	15	_	NUM	_	NumType=Card	_	_	_	_
47	min	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	surface	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	E	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	selectin	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	noted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	within	_	ADP	_	_	_	_	_	_
22	hours	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	C.	_	PROPN	_	Number=Sing	_	_	_	_
4	pneumoniae	_	PROPN	_	Number=Sing	_	_	_	_
5	triggers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	cascade	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	events	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	could	_	AUX	_	VerbForm=Fin	_	_	_	_
12	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	thrombosis	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	turn	_	NOUN	_	Number=Sing	_	_	_	_
25	may	_	AUX	_	VerbForm=Fin	_	_	_	_
26	result	_	VERB	_	VerbForm=Inf	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	may	_	AUX	_	VerbForm=Fin	_	_	_	_
30	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
31	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012161	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	functional	_	ADJ	_	Degree=Pos	_	_	_	_
3	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	signaling	_	NOUN	_	Number=Sing	_	_	_	_
6	pathway	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	p95vav	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
5	antigen	_	NOUN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	TCR	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
14	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
15	kinases	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	numerous	_	ADJ	_	Degree=Pos	_	_	_	_
22	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
23	substrates	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	substrate	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	p95vav	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Int	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	exclusively	_	ADV	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	trophoblast	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	number	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	structural	_	ADJ	_	Degree=Pos	_	_	_	_
7	motifs	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	including	_	VERB	_	VerbForm=Ger	_	_	_	_
10	Src	_	PROPN	_	Number=Sing	_	_	_	_
11	homology	_	NOUN	_	Number=Sing	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	Src	_	PROPN	_	Number=Sing	_	_	_	_
15	homology	_	NOUN	_	Number=Sing	_	_	_	_
16	3	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	pleckstrin	_	VERB	_	Number=Sing	_	_	_	_
20	homology	_	NOUN	_	Number=Sing	_	_	_	_
21	domains	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	putative	_	ADJ	_	Degree=Pos	_	_	_	_
25	guanine	_	NOUN	_	Number=Sing	_	_	_	_
26	nucleotide	_	ADJ	_	Number=Sing	_	_	_	_
27	exchange	_	NOUN	_	Number=Sing	_	_	_	_
28	domain	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p95vav	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	TCR	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	mediated	_	VERB	_	Degree=Pos	_	_	_	_
9	signaling	_	NOUN	_	Number=Sing	_	_	_	_
10	processes	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	p95vav	_	NOUN	_	Number=Sing	_	_	_	_
9	alone	_	ADJ	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	factors	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	including	_	VERB	_	VerbForm=Ger	_	_	_	_
23	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	involved	_	ADJ	_	Degree=Pos	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	p95vav	_	PROPN	_	Number=Sing	_	_	_	_
4	synergizes	_	VERB	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	TCR	_	NOUN	_	Number=Sing	_	_	_	_
7	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	interleukin	_	ADJ	_	Number=Sing	_	_	_	_
14	-2	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	NFAT	_	ADJ	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	G	_	NUM	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	p95vav	_	ADJ	_	Number=Sing	_	_	_	_
19	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	effect	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	TCR	_	NOUN	_	Number=Sing	_	_	_	_
30	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
31	pathways	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	removal	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	67	_	NUM	_	NumType=Card	_	_	_	_
7	amino	_	ADJ	_	Degree=Pos	_	_	_	_
8	acids	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	p95vav	_	NOUN	_	Number=Sing	_	_	_	_
11	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
14	potential	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	NIH	_	PROPN	_	Number=Sing	_	_	_	_
17	3T3	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	region	_	NOUN	_	Number=Sing	_	_	_	_
22	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	function	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	T	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	p95vav	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	mimicked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	Ras	_	PROPN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	though	_	SCONJ	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	function	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	upon	_	ADP	_	_	_	_	_	_
24	Ras	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	Raf	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	activating	_	NOUN	_	Degree=Pos	_	_	_	_
5	function	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	p95vav	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	FK506	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	also	_	ADV	_	_	_	_	_	_
18	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	dissect	_	VERB	_	VerbForm=Inf	_	_	_	_
4	p95vav	_	NOUN	_	Number=Sing	_	_	_	_
5	involvement	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	TCR	_	PROPN	_	Number=Sing	_	_	_	_
8	signaling	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	various	_	ADJ	_	Degree=Pos	_	_	_	_
13	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
14	mutants	_	NOUN	_	Number=Plur	_	_	_	_
15	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	TCR	_	NOUN	_	Number=Sing	_	_	_	_
18	signaling	_	NOUN	_	Number=Sing	_	_	_	_
19	function	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	TCR	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	intact	_	ADJ	_	Degree=Pos	_	_	_	_
28	TCR	_	NOUN	_	Number=Sing	_	_	_	_
29	signaling	_	NOUN	_	Number=Sing	_	_	_	_
30	pathway	_	NOUN	_	Number=Sing	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	for	_	ADP	_	_	_	_	_	_
34	p95vav	_	NOUN	_	Number=Sing	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	function	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	p95vav	_	NOUN	_	Number=Sing	_	_	_	_
6	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	appear	_	VERB	_	VerbForm=Inf	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
11	TCR	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
16	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	increases	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
21	free	_	ADJ	_	Degree=Pos	_	_	_	_
22	calcium	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	p95vav	_	PROPN	_	Number=Sing	_	_	_	_
9	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	important	_	ADJ	_	Degree=Pos	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	yet	_	ADV	_	_	_	_	_	_
16	unidentified	_	ADJ	_	Degree=Pos	_	_	_	_
17	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
18	position	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	TCR	_	NOUN	_	Number=Sing	_	_	_	_
22	signaling	_	NOUN	_	Number=Sing	_	_	_	_
23	cascade	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012169	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	immune	_	ADJ	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	disease	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	large	_	ADJ	_	Degree=Pos	_	_	_	_
3	amount	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	detailed	_	ADJ	_	Degree=Pos	_	_	_	_
6	information	_	NOUN	_	Number=Sing	_	_	_	_
7	about	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
20	response	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	PROPN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	emerged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	recently	_	ADV	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	small	_	ADJ	_	Degree=Pos	_	_	_	_
3	molecules	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	antisense	_	ADJ	_	Degree=Pos	_	_	_	_
7	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	gene	_	VERB	_	Number=Sing	_	_	_	_
11	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
12	agents	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	b	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
22	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Despite	_	ADP	_	_	_	_	_	_
2	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	there	_	PRON	_	_	_	_	_	_
5	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	still	_	ADV	_	_	_	_	_	_
7	significant	_	ADJ	_	Degree=Pos	_	_	_	_
8	gaps	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
11	understanding	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	process	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	consequences	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	characterization	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	selectively	_	ADV	_	_	_	_	_	_
10	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	CD4	_	PROPN	_	Number=Sing	_	_	_	_
15	+	_	SYM	_	_	_	_	_	_

1	T	_	DET	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	subsets	_	NOUN	_	Number=Plur	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	very	_	ADV	_	_	_	_	_	_
8	early	_	ADJ	_	Degree=Pos	_	_	_	_
9	stage	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Three	_	NUM	_	NumType=Card	_	_	_	_
2	interacting	_	ADJ	_	VerbForm=Ger	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	recently	_	ADV	_	_	_	_	_	_
6	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
7	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	subset	_	NOUN	_	VerbForm=Inf	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	4	_	NUM	_	NumType=Card	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	elements	_	NOUN	_	Number=Plur	_	_	_	_
5	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	however	_	ADV	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	relative	_	ADJ	_	Degree=Pos	_	_	_	_
17	importance	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
20	recently	_	ADV	_	_	_	_	_	_
21	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	yet	_	ADV	_	_	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	be	_	AUX	_	VerbForm=Inf	_	_	_	_
27	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012174	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Separation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	oxidant	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	redox	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	steps	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	signal	_	NOUN	_	Number=Sing	_	_	_	_
18	transduction	_	NOUN	_	Number=Sing	_	_	_	_
19	pathway	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	PROPN	_	Number=Plur	_	_	_	_
2	presented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	overall	_	ADJ	_	Degree=Pos	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	signal	_	NOUN	_	Number=Sing	_	_	_	_
12	transduction	_	NOUN	_	Number=Sing	_	_	_	_
13	begins	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	parallel	_	ADJ	_	Degree=Pos	_	_	_	_
17	series	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	stimuli	_	ADJ	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	specific	_	ADJ	_	Degree=Pos	_	_	_	_
22	pathways	_	NOUN	_	Number=Plur	_	_	_	_
23	through	_	ADP	_	_	_	_	_	_
24	which	_	DET	_	PronType=Rel	_	_	_	_
25	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	tumor	_	NOUN	_	Number=Sing	_	_	_	_
28	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	oxidants	_	NOUN	_	Number=Plur	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	hydrogen	_	NOUN	_	Number=Sing	_	_	_	_
36	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	mitomycin	_	NOUN	_	Number=Sing	_	_	_	_
39	C	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
44	ester	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
47	12	_	NUM	_	NumType=Card	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	myristate	_	NOUN	_	Number=Sing	_	_	_	_
50	13	_	NUM	_	NumType=Card	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	acetate	_	NOUN	_	Number=Sing	_	_	_	_
53	)	_	PUNCT	_	_	_	_	_	_
54	individually	_	ADV	_	_	_	_	_	_
55	initiate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
56	signaling	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	initial	_	ADJ	_	Degree=Pos	_	_	_	_
3	pathways	_	NOUN	_	Number=Plur	_	_	_	_
4	culminate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	common	_	ADJ	_	Degree=Pos	_	_	_	_
8	pathway	_	NOUN	_	Number=Sing	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	all	_	DET	_	_	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
15	agents	_	NOUN	_	Number=Plur	_	_	_	_
16	ultimately	_	ADV	_	_	_	_	_	_
17	signal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	distinguish	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	stimuli	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	pathways	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	SCONJ	_	_	_	_	_	_
9	showing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
13	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
14	trigger	_	VERB	_	Number=Sing	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	only	_	ADV	_	_	_	_	_	_
22	one	_	NUM	_	NumType=Card	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	two	_	NUM	_	NumType=Card	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
27	lines	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	Wurzburg	_	PROPN	_	Number=Sing	_	_	_	_
30	but	_	CCONJ	_	_	_	_	_	_
31	not	_	ADV	_	_	_	_	_	_
32	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	whereas	_	SCONJ	_	_	_	_	_	_
36	tumor	_	NOUN	_	Number=Sing	_	_	_	_
37	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
38	factor	_	NOUN	_	Number=Sing	_	_	_	_
39	alpha	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
42	12	_	NUM	_	NumType=Card	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	myristate	_	NOUN	_	Number=Sing	_	_	_	_
45	13	_	NUM	_	NumType=Card	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	acetate	_	NOUN	_	Number=Sing	_	_	_	_
48	readily	_	ADV	_	_	_	_	_	_
49	stimulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
50	in	_	ADP	_	_	_	_	_	_
51	both	_	DET	_	_	_	_	_	_
52	lines	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	common	_	ADJ	_	Degree=Pos	_	_	_	_
5	pathway	_	NOUN	_	Number=Sing	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	simplest	_	ADJ	_	Degree=Sup	_	_	_	_
9	way	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	accounting	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	common	_	ADJ	_	Degree=Pos	_	_	_	_
15	requirements	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	properties	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	signaling	_	NOUN	_	Number=Sing	_	_	_	_
21	pathway	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	redox	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	s	_	X	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	common	_	ADJ	_	Degree=Pos	_	_	_	_
14	pathway	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	account	_	VERB	_	VerbForm=Inf	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	previously	_	ADV	_	_	_	_	_	_
20	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	redox	_	NOUN	_	Degree=Pos	_	_	_	_
22	regulation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	which	_	PRON	_	PronType=Rel	_	_	_	_
35	oxidants	_	NOUN	_	Number=Plur	_	_	_	_
36	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
37	n't	_	PART	_	_	_	_	_	_
38	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappa	_	PROPN	_	Number=Sing	_	_	_	_
42	B	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	;	_	PUNCT	_	_	_	_	_	_
45	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
46	put	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
47	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
48	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	common	_	ADJ	_	Degree=Pos	_	_	_	_
52	pathway	_	NOUN	_	Number=Sing	_	_	_	_
53	by	_	SCONJ	_	_	_	_	_	_
54	showing	_	VERB	_	VerbForm=Ger	_	_	_	_
55	that	_	DET	_	_	_	_	_	_
56	kinase	_	NOUN	_	Number=Sing	_	_	_	_
57	activity	_	NOUN	_	Number=Sing	_	_	_	_
58	(	_	PUNCT	_	_	_	_	_	_
59	inhibitable	_	ADJ	_	Degree=Pos	_	_	_	_
60	by	_	ADP	_	_	_	_	_	_
61	herbimycin	_	NOUN	_	Number=Sing	_	_	_	_
62	A	_	NOUN	_	Number=Sing	_	_	_	_
63	and	_	CCONJ	_	_	_	_	_	_
64	tyrphostin	_	PROPN	_	Number=Sing	_	_	_	_
65	47	_	NUM	_	NumType=Card	_	_	_	_
66	)	_	PUNCT	_	_	_	_	_	_
67	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
68	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
69	for	_	ADP	_	_	_	_	_	_
70	NF	_	PROPN	_	Number=Sing	_	_	_	_
71	-	_	PUNCT	_	_	_	_	_	_
72	kappa	_	NOUN	_	Number=Sing	_	_	_	_
73	B	_	NOUN	_	Number=Sing	_	_	_	_
74	activation	_	NOUN	_	Number=Sing	_	_	_	_
75	by	_	ADP	_	_	_	_	_	_
76	all	_	DET	_	_	_	_	_	_
77	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
78	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
79	in	_	ADP	_	_	_	_	_	_
80	both	_	DET	_	_	_	_	_	_
81	cell	_	NOUN	_	Number=Sing	_	_	_	_
82	lines	_	NOUN	_	Number=Plur	_	_	_	_
83	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	internal	_	ADJ	_	Degree=Pos	_	_	_	_
3	sites	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	oxidant	_	ADJ	_	Number=Sing	_	_	_	_
6	production	_	NOUN	_	Number=Sing	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
9	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	play	_	VERB	_	VerbForm=Inf	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	key	_	ADJ	_	Degree=Pos	_	_	_	_
14	role	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	since	_	SCONJ	_	_	_	_	_	_
29	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
30	kinase	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
33	activities	_	NOUN	_	Number=Plur	_	_	_	_
34	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	be	_	AUX	_	VerbForm=Inf	_	_	_	_
38	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	oxidants	_	NOUN	_	Number=Plur	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
43	findings	_	NOUN	_	Number=Plur	_	_	_	_
44	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
45	that	_	SCONJ	_	_	_	_	_	_
46	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
47	redox	_	NOUN	_	Number=Sing	_	_	_	_
48	status	_	NOUN	_	Number=Sing	_	_	_	_
49	controls	_	NOUN	_	Number=Sing	_	_	_	_
50	NF	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	kappa	_	NOUN	_	Number=Sing	_	_	_	_
53	B	_	NOUN	_	Number=Sing	_	_	_	_
54	activation	_	NOUN	_	Number=Sing	_	_	_	_
55	by	_	SCONJ	_	_	_	_	_	_
56	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
57	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
58	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
59	event	_	NOUN	_	Number=Sing	_	_	_	_
60	(	_	PUNCT	_	_	_	_	_	_
61	s	_	X	_	_	_	_	_	_
62	)	_	PUNCT	_	_	_	_	_	_
63	within	_	ADP	_	_	_	_	_	_
64	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
65	common	_	ADJ	_	Degree=Pos	_	_	_	_
66	step	_	NOUN	_	Number=Sing	_	_	_	_
67	of	_	ADP	_	_	_	_	_	_
68	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
69	NF	_	PROPN	_	Number=Sing	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	kappa	_	NOUN	_	Number=Sing	_	_	_	_
72	B	_	NOUN	_	Number=Sing	_	_	_	_
73	signal	_	NOUN	_	Number=Sing	_	_	_	_
74	transduction	_	NOUN	_	Number=Sing	_	_	_	_
75	pathway	_	NOUN	_	Number=Sing	_	_	_	_
76	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012180	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CD30	_	PROPN	_	Number=Sing	_	_	_	_
2	ligation	_	NOUN	_	Number=Sing	_	_	_	_
3	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	lines	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	CD30	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	recently	_	ADV	_	_	_	_	_	_
5	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	member	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	nerve	_	ADJ	_	Degree=Pos	_	_	_	_
14	growth	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	following	_	VERB	_	VerbForm=Ger	_	_	_	_
9	incubation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	L540	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	Hodgkin	_	PROPN	_	Number=Sing	_	_	_	_
15	's	_	PART	_	_	_	_	_	_
16	disease	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	like	_	ADP	_	Degree=Pos	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	CD30	_	NOUN	_	Number=Sing	_	_	_	_
7	+	_	SYM	_	_	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	agonistic	_	ADJ	_	Degree=Pos	_	_	_	_
13	anti-CD30	_	ADJ	_	Number=Sing	_	_	_	_
14	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
15	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	mAb	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	M44	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	M67	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	two	_	NUM	_	NumType=Card	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	DNA	_	NOUN	_	Number=Sing	_	_	_	_
33	binding	_	NOUN	_	Number=Sing	_	_	_	_
34	activities	_	NOUN	_	Number=Plur	_	_	_	_
35	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
39	extracts	_	NOUN	_	Number=Plur	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	as	_	SCONJ	_	_	_	_	_	_
42	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	gel	_	NOUN	_	Number=Sing	_	_	_	_
45	retardation	_	NOUN	_	Number=Sing	_	_	_	_
46	assays	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	mAb	_	NOUN	_	Number=Sing	_	_	_	_
6	towards	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	as	_	SCONJ	_	_	_	_	_	_
16	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
17	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	within	_	ADP	_	_	_	_	_	_
19	20	_	NUM	_	NumType=Card	_	_	_	_
20	min	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	sustained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	up	_	ADP	_	_	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	6	_	NUM	_	NumType=Card	_	_	_	_
29	h	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	comparison	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	isotype	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	matched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	antibody	_	NOUN	_	Number=Sing	_	_	_	_
9	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	no	_	DET	_	_	_	_	_	_
11	effect	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	helper	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	Th	_	NOUN	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	clones	_	NOUN	_	Number=Plur	_	_	_	_
11	functionally	_	ADV	_	_	_	_	_	_
12	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	being	_	AUX	_	VerbForm=Ger	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	0	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	type	_	NOUN	_	Number=Sing	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	28	_	NUM	_	NumType=Card	_	_	_	_
27	%	_	SYM	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	<	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	%	_	SYM	_	Number=Sing	_	_	_	_
32	und	_	NUM	_	_	_	_	_	_
33	93	_	NUM	_	NumType=Card	_	_	_	_
34	%	_	SYM	_	Number=Sing	_	_	_	_
35	CD30	_	NOUN	_	Number=Sing	_	_	_	_
36	+	_	SYM	_	_	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	respectively	_	ADV	_	_	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	extent	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	CD30	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	NF	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	kappa	_	NOUN	_	Number=Sing	_	_	_	_
50	B	_	NOUN	_	Number=Sing	_	_	_	_
51	activation	_	NOUN	_	Number=Sing	_	_	_	_
52	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
53	with	_	ADP	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	proportion	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	CD30	_	NOUN	_	Number=Sing	_	_	_	_
58	+	_	SYM	_	_	_	_	_	_
59	cells	_	NOUN	_	Number=Plur	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	all	_	DET	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	complexes	_	NOUN	_	Number=Plur	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	following	_	VERB	_	VerbForm=Ger	_	_	_	_
15	CD30	_	PROPN	_	Number=Sing	_	_	_	_
16	engagement	_	NOUN	_	Number=Sing	_	_	_	_
17	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
21	p50	_	NUM	_	Number=Sing	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B1	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	p65	_	NOUN	_	Number=Sing	_	_	_	_
28	RelA	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	possibly	_	ADV	_	_	_	_	_	_
32	other	_	ADJ	_	Degree=Pos	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	factors	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Collectively	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	translocation	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	rank	_	NOUN	_	Number=Sing	_	_	_	_
17	among	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	short	_	ADJ	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	term	_	NOUN	_	Number=Sing	_	_	_	_
22	cellular	_	ADJ	_	Number=Sing	_	_	_	_
23	responses	_	NOUN	_	Number=Plur	_	_	_	_
24	elicited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	following	_	VERB	_	VerbForm=Ger	_	_	_	_
26	CD30	_	PROPN	_	Number=Sing	_	_	_	_
27	ligation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012181	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Downregulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Wilms	_	PROPN	_	Number=Sing	_	_	_	_
4	'	_	PART	_	_	_	_	_	_
5	tumor	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	WT1	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	prerequisite	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	K562	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Wilms	_	PROPN	_	Number=Plur	_	_	_	_
3	'	_	PART	_	_	_	_	_	_
4	tumor	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	WT1	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	zinc	_	NOUN	_	Number=Sing	_	_	_	_
16	finger	_	NOUN	_	Number=Sing	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	high	_	ADJ	_	Degree=Pos	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	WT1	_	PROPN	_	Number=Sing	_	_	_	_
6	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	range	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	acute	_	ADJ	_	Degree=Pos	_	_	_	_
14	leukemias	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	WT1	_	PROPN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	downregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	during	_	ADP	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	some	_	DET	_	_	_	_	_	_
25	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	lines	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	WT1	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	some	_	DET	_	_	_	_	_	_
6	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	resistance	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	high	_	ADJ	_	Degree=Pos	_	_	_	_
7	WT1	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	incompatible	_	ADJ	_	Degree=Pos	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	each	_	DET	_	_	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	four	_	NUM	_	NumType=Card	_	_	_	_
9	different	_	ADJ	_	Degree=Pos	_	_	_	_
10	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	WT1	_	PROPN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	constitutively	_	ADV	_	_	_	_	_	_
15	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	line	_	NOUN	_	Number=Sing	_	_	_	_
21	K562	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	K562	_	NUM	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
5	WT1	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	downregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	along	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	pathways	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	forced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	four	_	NUM	_	NumType=Card	_	_	_	_
12	different	_	ADJ	_	Degree=Pos	_	_	_	_
13	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	WT1	_	PROPN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	K562	_	PROPN	_	Number=Sing	_	_	_	_
18	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	as	_	SCONJ	_	_	_	_	_	_
26	judged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	hemoglobin	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	response	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	hemin	_	NOUN	_	Number=Sing	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	expression	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	surface	_	NOUN	_	Number=Sing	_	_	_	_
42	markers	_	NOUN	_	Number=Plur	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	response	_	NOUN	_	Number=Sing	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	13	_	NUM	_	NumType=Card	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	acetate	_	NOUN	_	Number=Sing	_	_	_	_
51	(	_	PUNCT	_	_	_	_	_	_
52	TPA	_	NOUN	_	Number=Sing	_	_	_	_
53	)	_	PUNCT	_	_	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	downregulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	WT1	_	PROPN	_	Number=Sing	_	_	_	_
7	during	_	ADP	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	K562	_	NUM	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	prerequisite	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012183	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	critical	_	ADJ	_	Degree=Pos	_	_	_	_
3	role	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	p75	_	NUM	_	NumType=Card	_	_	_	_
7	tumor	_	NOUN	_	Number=Sing	_	_	_	_
8	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	p75TNF	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	R	_	X	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	organ	_	ADJ	_	Degree=Pos	_	_	_	_
18	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
19	independent	_	ADJ	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	TNF	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	lymphotoxin	_	PROPN	_	Number=Sing	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	p55TNF	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	R.	_	PROPN	_	Number=Sing	_	_	_	_
31	Despite	_	ADP	_	_	_	_	_	_
32	overwhelming	_	ADJ	_	Degree=Pos	_	_	_	_
33	evidence	_	NOUN	_	Number=Sing	_	_	_	_
34	that	_	PRON	_	_	_	_	_	_
35	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	production	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	p75	_	NUM	_	NumType=Card	_	_	_	_
40	tumor	_	NOUN	_	Number=Sing	_	_	_	_
41	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
42	factor	_	NOUN	_	Number=Sing	_	_	_	_
43	receptor	_	NOUN	_	Number=Sing	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	p75TNF	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	R	_	NOUN	_	Number=Sing	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	accompanies	_	VERB	_	Number=Plur	_	_	_	_
50	development	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	specific	_	ADJ	_	Degree=Pos	_	_	_	_
53	human	_	ADJ	_	Degree=Pos	_	_	_	_
54	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
55	pathologies	_	NOUN	_	Number=Plur	_	_	_	_
56	such	_	ADJ	_	Degree=Pos	_	_	_	_
57	as	_	ADP	_	_	_	_	_	_
58	multi-organ	_	ADJ	_	Degree=Pos	_	_	_	_
59	failure	_	NOUN	_	Number=Sing	_	_	_	_
60	during	_	ADP	_	_	_	_	_	_
61	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
64	liver	_	NOUN	_	Number=Sing	_	_	_	_
65	disease	_	NOUN	_	Number=Sing	_	_	_	_
66	,	_	PUNCT	_	_	_	_	_	_
67	pancreatitis	_	NOUN	_	Number=Sing	_	_	_	_
68	,	_	PUNCT	_	_	_	_	_	_
69	respiratory	_	ADJ	_	Degree=Pos	_	_	_	_
70	distress	_	NOUN	_	Number=Sing	_	_	_	_
71	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
72	,	_	PUNCT	_	_	_	_	_	_
73	or	_	CCONJ	_	_	_	_	_	_
74	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
75	,	_	PUNCT	_	_	_	_	_	_
76	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
77	function	_	NOUN	_	Number=Sing	_	_	_	_
78	of	_	ADP	_	_	_	_	_	_
79	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
80	receptor	_	NOUN	_	Number=Sing	_	_	_	_
81	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
82	poorly	_	ADV	_	_	_	_	_	_
83	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
84	in	_	ADP	_	_	_	_	_	_
85	vivo	_	NOUN	_	Number=Sing	_	_	_	_
86	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	disease	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	p75TNF	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	R	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
21	mice	_	NOUN	_	Number=Plur	_	_	_	_
22	results	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	severe	_	ADJ	_	Degree=Pos	_	_	_	_
26	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
28	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
29	mainly	_	ADV	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	pancreas	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	liver	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	kidney	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	lung	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	by	_	ADP	_	_	_	_	_	_
43	constitutively	_	ADV	_	_	_	_	_	_
44	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	NF	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
48	activity	_	NOUN	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
52	blood	_	NOUN	_	Number=Sing	_	_	_	_
53	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
54	cell	_	NOUN	_	Number=Sing	_	_	_	_
55	compartment	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	process	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	evolve	_	VERB	_	VerbForm=Inf	_	_	_	_
7	independently	_	ADV	_	_	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	presence	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	lymphotoxin	_	PROPN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	p55TNF	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	R	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	although	_	SCONJ	_	_	_	_	_	_
24	coexpression	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	TNF	_	NOUN	_	Number=Sing	_	_	_	_
29	transgene	_	NOUN	_	Number=Sing	_	_	_	_
30	accelerated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	pathology	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	establish	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	independent	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	p75TNF	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	R	_	NOUN	_	Number=Sing	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	disease	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	implicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	direct	_	ADJ	_	Degree=Pos	_	_	_	_
23	involvement	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	wide	_	ADJ	_	Degree=Pos	_	_	_	_
30	range	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	human	_	ADJ	_	Degree=Pos	_	_	_	_
33	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
34	pathologies	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012196	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	Ets	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	related	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	Elf	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	elements	_	NOUN	_	Number=Plur	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
27	trans	_	NOUN	_	Number=Plur	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	T	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	structurally	_	ADV	_	_	_	_	_	_
17	related	_	ADJ	_	Degree=Pos	_	_	_	_
18	retroviruses	_	NOUN	_	Number=Plur	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	both	_	DET	_	_	_	_	_	_
21	cause	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	humans	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	both	_	DET	_	_	_	_	_	_
3	viruses	_	NOUN	_	Number=Plur	_	_	_	_
4	establish	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	latency	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	quiescent	_	ADJ	_	Degree=Pos	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	blood	_	NOUN	_	Number=Sing	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	asymptomatic	_	ADJ	_	Degree=Pos	_	_	_	_
18	phase	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	infection	_	NOUN	_	Number=Sing	_	_	_	_
24	may	_	AUX	_	VerbForm=Fin	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	more	_	ADV	_	_	_	_	_	_
27	prolonged	_	ADJ	_	Degree=Pos	_	_	_	_
28	than	_	ADP	_	_	_	_	_	_
29	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	HIV	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	latent	_	ADJ	_	Degree=Pos	_	_	_	_
3	phases	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	both	_	CCONJ	_	_	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	infection	_	NOUN	_	Number=Sing	_	_	_	_
14	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	disrupted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	process	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	host	_	ADJ	_	Number=Sing	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	factors	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	case	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	addition	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	novel	_	NOUN	_	Number=Sing	_	_	_	_
10	Ets	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	related	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	Elf	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	specifically	_	ADV	_	_	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	two	_	NUM	_	NumType=Card	_	_	_	_
24	purine	_	ADJ	_	Degree=Pos	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	rich	_	ADJ	_	Degree=Pos	_	_	_	_
27	motifs	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	HIV	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Mutagenesis	_	PROPN	_	Number=Sing	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	Elf	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	sites	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	induction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	following	_	VERB	_	VerbForm=Ger	_	_	_	_
21	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_

1	Elf	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	only	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	present	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	extracts	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
21	mobility	_	NOUN	_	Number=Sing	_	_	_	_
22	shift	_	NOUN	_	Number=Sing	_	_	_	_
23	assays	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Elf	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	novel	_	NOUN	_	Number=Sing	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	receptor	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
23	trans	_	NOUN	_	Number=Plur	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	HIV	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	may	_	AUX	_	VerbForm=Fin	_	_	_	_
4	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
5	differences	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
9	spectra	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	diseases	_	NOUN	_	Number=Plur	_	_	_	_
12	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	HIV	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	may	_	AUX	_	VerbForm=Fin	_	_	_	_
23	also	_	ADV	_	_	_	_	_	_
24	have	_	VERB	_	VerbForm=Inf	_	_	_	_
25	implications	_	NOUN	_	Number=Plur	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	design	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	therapeutic	_	ADJ	_	Number=Sing	_	_	_	_
31	approaches	_	NOUN	_	Number=Plur	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	HIV	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	infection	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012198	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	T	_	NUM	_	NumType=Card	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	locus	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	cooperatively	_	ADV	_	_	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	Oct	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	NFAT	_	ADJ	_	Number=Sing	_	_	_	_
20	elements	_	NOUN	_	Number=Plur	_	_	_	_
21	within	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	DNase	_	NOUN	_	Number=Sing	_	_	_	_
24	I	_	PRON	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
27	site	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-3	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	primarily	_	ADV	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
11	14	_	NUM	_	NumType=Card	_	_	_	_
12	kb	_	NOUN	_	Number=Sing	_	_	_	_
13	upstream	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	3	_	NUM	_	NumType=Card	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	responded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	T	_	PROPN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	signaling	_	NOUN	_	Number=Sing	_	_	_	_
29	pathways	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	3	_	NUM	_	NumType=Card	_	_	_	_
5	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
6	spanned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
9	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
10	A	_	NOUN	_	Definite=Ind|PronType=Art	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
13	DNase	_	NOUN	_	Number=Sing	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
17	site	_	NOUN	_	Number=Sing	_	_	_	_
18	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	only	_	ADV	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Four	_	NUM	_	NumType=Card	_	_	_	_
2	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	like	_	ADJ	_	Degree=Pos	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	exist	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	within	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	most	_	ADV	_	_	_	_	_	_
4	active	_	ADJ	_	Degree=Pos	_	_	_	_
5	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	like	_	ADJ	_	Degree=Pos	_	_	_	_
8	elements	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	center	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	DNase	_	PROPN	_	Number=Sing	_	_	_	_
17	I	_	PRON	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	NFAT	_	NOUN	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	like	_	ADJ	_	Degree=Pos	_	_	_	_
7	elements	_	NOUN	_	Number=Plur	_	_	_	_
8	encompassed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	overlapping	_	ADJ	_	Degree=Pos	_	_	_	_
10	Oct	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	c-binding	_	NOUN	_	Number=Sing	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	functioned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	highly	_	ADV	_	_	_	_	_	_
23	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
24	manner	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	T	_	PROPN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	3	_	NUM	_	NumType=Card	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	partly	_	ADV	_	_	_	_	_	_
18	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	through	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
24	between	_	ADP	_	_	_	_	_	_
25	Oct	_	PROPN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
28	family	_	NOUN	_	Number=Sing	_	_	_	_
29	proteins	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012203	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	allosteric	_	ADJ	_	Degree=Pos	_	_	_	_
3	drug	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	o,o	_	NOUN	_	Number=Sing	_	_	_	_
6	'-	_	PUNCT	_	_	_	_	_	_
7	bismyristoyl	_	ADJ	_	Degree=Pos	_	_	_	_
8	thiamine	_	NOUN	_	Number=Sing	_	_	_	_
9	disulfide	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	replication	_	NOUN	_	Number=Sing	_	_	_	_
16	through	_	ADP	_	_	_	_	_	_
17	prevention	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	translocation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	HIV	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	Tat	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B.	_	PROPN	_	Number=Sing	_	_	_	_
32	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	efficacy	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	o,o	_	PROPN	_	Number=Sing	_	_	_	_
36	'-	_	PUNCT	_	_	_	_	_	_
37	bismyristoyl	_	ADJ	_	Number=Sing	_	_	_	_
38	thiamine	_	NOUN	_	Number=Sing	_	_	_	_
39	disulfide	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	BMT	_	PROPN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
44	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	detail	_	NOUN	_	Number=Sing	_	_	_	_
47	against	_	ADP	_	_	_	_	_	_
48	HIV	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	1	_	NUM	_	NumType=Card	_	_	_	_
51	laboratory	_	NOUN	_	Number=Sing	_	_	_	_
52	isolates	_	NOUN	_	Number=Plur	_	_	_	_
53	(	_	PUNCT	_	_	_	_	_	_
54	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	IIIB	_	PROPN	_	Number=Sing	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	JRFL	_	PROPN	_	Number=Sing	_	_	_	_
59	,	_	PUNCT	_	_	_	_	_	_
60	and	_	CCONJ	_	_	_	_	_	_
61	MN	_	PROPN	_	Number=Sing	_	_	_	_
62	)	_	PUNCT	_	_	_	_	_	_
63	,	_	PUNCT	_	_	_	_	_	_
64	primary	_	ADJ	_	Degree=Pos	_	_	_	_
65	isolates	_	NOUN	_	Number=Plur	_	_	_	_
66	(	_	PUNCT	_	_	_	_	_	_
67	KMT	_	PROPN	_	Number=Sing	_	_	_	_
68	and	_	CCONJ	_	_	_	_	_	_
69	KMO	_	PROPN	_	Number=Sing	_	_	_	_
70	)	_	PUNCT	_	_	_	_	_	_
71	,	_	PUNCT	_	_	_	_	_	_
72	and	_	CCONJ	_	_	_	_	_	_
73	simian	_	ADJ	_	Degree=Pos	_	_	_	_
74	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
75	virus	_	NOUN	_	Number=Sing	_	_	_	_
76	(	_	PUNCT	_	_	_	_	_	_
77	SIVmac251	_	X	_	Number=Sing	_	_	_	_
78	)	_	PUNCT	_	_	_	_	_	_
79	in	_	ADP	_	_	_	_	_	_
80	vitro	_	NOUN	_	Number=Sing	_	_	_	_
81	.	_	PUNCT	_	_	_	_	_	_

1	BMT	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	replication	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	laboratory	_	ADJ	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	primary	_	ADJ	_	Degree=Pos	_	_	_	_
14	isolates	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	vitro	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	BMT	_	PROPN	_	Number=Sing	_	_	_	_
5	exhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	antiviral	_	ADJ	_	Degree=Pos	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	against	_	ADP	_	_	_	_	_	_
9	SIVmac251	_	PROPN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Minimizing	_	VERB	_	VerbForm=Ger	_	_	_	_
2	energy	_	NOUN	_	Number=Sing	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	BMT	_	NOUN	_	Number=Sing	_	_	_	_
6	structure	_	NOUN	_	Number=Sing	_	_	_	_
7	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	trans	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	disulfide	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	thiamine	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	holo	_	NOUN	_	Number=Sing	_	_	_	_
17	drug	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	disulfide	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	TDS	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	protodrug	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	allosterically	_	ADV	_	_	_	_	_	_
27	transited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
31	twisted	_	ADJ	_	Degree=Pos	_	_	_	_
32	disulfide	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	BMT	_	PROPN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	allo	_	NOUN	_	_	_	_	_	_
37	drug	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	o,o	_	ADJ	_	Number=Sing	_	_	_	_
41	'-	_	PUNCT	_	_	_	_	_	_
42	bismyristoyl	_	ADJ	_	Number=Sing	_	_	_	_
43	esterification	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	TDS	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	BMT	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	translocation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	TAT	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	KB	_	PROPN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	suppression	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	HIV	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	replication	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012206	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	lymphoblastoid	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	low	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dose	_	NOUN	_	Number=Sing	_	_	_	_
15	ionizing	_	VERB	_	Number=Sing	_	_	_	_
16	radiation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	pleiotropic	_	ADJ	_	Degree=Pos	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	involved	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	regulation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	several	_	ADJ	_	Degree=Pos	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	reports	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	ionizing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	radiation	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	dose	_	NOUN	_	Number=Sing	_	_	_	_
10	range	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	2-50	_	NUM	_	NumType=Card	_	_	_	_
13	Gy	_	NOUN	_	Number=Sing	_	_	_	_
14	results	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	KG	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
28	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
35	precursor	_	NOUN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	;	_	PUNCT	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	precise	_	ADJ	_	Number=Sing	_	_	_	_
40	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
41	involved	_	ADJ	_	Degree=Pos	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	significance	_	NOUN	_	Number=Sing	_	_	_	_
45	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
46	not	_	PART	_	_	_	_	_	_
47	yet	_	ADV	_	_	_	_	_	_
48	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	even	_	ADV	_	_	_	_	_	_
7	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
8	doses	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	ionizing	_	VERB	_	Number=Sing	_	_	_	_
11	radiation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	0.25	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	2.0	_	NUM	_	NumType=Card	_	_	_	_
16	Gy	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	capable	_	ADJ	_	Degree=Pos	_	_	_	_
20	of	_	SCONJ	_	_	_	_	_	_
21	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	EBV	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	244B	_	NUM	_	NumType=Card	_	_	_	_
33	human	_	ADJ	_	Degree=Pos	_	_	_	_
34	lymphoblastoid	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	dose	_	NOUN	_	Number=Sing	_	_	_	_
7	range	_	NOUN	_	Number=Sing	_	_	_	_
8	where	_	ADV	_	PronType=Rel	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	viability	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	very	_	ADV	_	_	_	_	_	_
16	high	_	ADJ	_	Degree=Pos	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	exposure	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	137Cs	_	NOUN	_	Number=Plur	_	_	_	_
5	gamma	_	NOUN	_	Number=Sing	_	_	_	_
6	rays	_	NOUN	_	Number=Plur	_	_	_	_
7	at	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	dose	_	NOUN	_	Number=Sing	_	_	_	_
10	rate	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	1.17	_	NUM	_	NumType=Card	_	_	_	_
13	Gy	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	min	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	maximum	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	at	_	ADP	_	_	_	_	_	_
29	8	_	NUM	_	NumType=Card	_	_	_	_
30	h	_	NOUN	_	Number=Sing	_	_	_	_
31	after	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	0.5	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	Gy	_	NOUN	_	Number=Sing	_	_	_	_
36	exposure	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Time	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	course	_	NOUN	_	Number=Sing	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
8	time	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	0.5	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	SYM	_	_	_	_	_	_
21	Gy	_	NOUN	_	Number=Sing	_	_	_	_
22	exposures	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	each	_	DET	_	_	_	_	_	_
5	time	_	NOUN	_	Number=Sing	_	_	_	_
6	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	maximum	_	ADJ	_	Degree=Pos	_	_	_	_
17	after	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	0.5	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	Gy	_	NOUN	_	Number=Sing	_	_	_	_
22	exposure	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	p50	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	p65	_	NUM	_	Number=Sing	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	subunits	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	differentially	_	ADV	_	_	_	_	_	_
20	after	_	ADP	_	_	_	_	_	_
21	exposures	_	NOUN	_	Number=Plur	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	1.0	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	2.0	_	NUM	_	NumType=Card	_	_	_	_
26	Gy.	_	PROPN	_	Number=Sing	_	_	_	_
27	Document	_	NOUN	_	Number=Sing	_	_	_	_
28	0030012208	_	NUM	_	NumType=Card	_	_	_	_
29	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	stabilizes	_	VERB	_	Number=Plur	_	_	_	_
5	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-10	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	10	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	protects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	animals	_	NOUN	_	Number=Plur	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	lethal	_	ADJ	_	Degree=Pos	_	_	_	_
11	endotoxemia	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	beneficial	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	mediated	_	VERB	_	Degree=Pos	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	part	_	ADJ	_	Degree=Pos	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
15	production	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	including	_	VERB	_	VerbForm=Ger	_	_	_	_
18	tumor	_	NOUN	_	Number=Sing	_	_	_	_
19	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	TNF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	10	_	NUM	_	NumType=Card	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	through	_	ADP	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
26	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	signals	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	upon	_	ADP	_	_	_	_	_	_
13	degradation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
18	peptide	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	hypothesized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	10	_	NUM	_	NumType=Card	_	_	_	_
7	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	resultant	_	ADJ	_	Degree=Pos	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	production	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	stabilization	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	purpose	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	effect	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	10	_	NUM	_	NumType=Card	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	LPS	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
24	TNF	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	production	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	IkappaB	_	ADJ	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	degradation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Monocytes	_	NOUN	_	Number=Plur	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	donors	_	NOUN	_	Number=Plur	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	Cells	_	NOUN	_	Number=Plur	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	LPS	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	100	_	NUM	_	NumType=Card	_	_	_	_
10	ng	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	mL	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	without	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	IL	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	10	_	NUM	_	NumType=Card	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	10	_	NUM	_	NumType=Card	_	_	_	_
23	ng	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	SYM	_	_	_	_	_	_
25	mL	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Following	_	VERB	_	VerbForm=Ger	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	measured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	supernatants	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	ELISA	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
21	mobility	_	NOUN	_	Number=Sing	_	_	_	_
22	shift	_	NOUN	_	Number=Sing	_	_	_	_
23	assay	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	IkappaB	_	ADJ	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	levels	_	NOUN	_	Number=Plur	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	Western	_	ADJ	_	Degree=Pos	_	_	_	_
32	blot	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	after	_	ADP	_	_	_	_	_	_
5	LPS	_	NOUN	_	Number=Sing	_	_	_	_
6	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	798+/-67	_	NUM	_	NumType=Card	_	_	_	_
17	pg/mL	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	p	_	NOUN	_	Number=Sing	_	_	_	_
20	<	_	PUNCT	_	_	_	_	_	_
21	.001	_	NUM	_	NumType=Card	_	_	_	_
22	versus	_	ADP	_	_	_	_	_	_
23	control	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	attenuated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	LPS	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	297+/-54	_	NUM	_	NumType=Card	_	_	_	_
14	;	_	PUNCT	_	_	_	_	_	_
15	p	_	NOUN	_	Number=Sing	_	_	_	_
16	<	_	PUNCT	_	_	_	_	_	_
17	.001	_	NUM	_	NumType=Card	_	_	_	_
18	versus	_	ADP	_	_	_	_	_	_
19	LPS	_	PROPN	_	Number=Sing	_	_	_	_
20	alone	_	ADV	_	_	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	LPS	_	NOUN	_	Number=Sing	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	IkappaB	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	DNA	_	NOUN	_	Number=Sing	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
5	prevented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	LPS	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	decreases	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	attenuated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	preserving	_	VERB	_	VerbForm=Ger	_	_	_	_
14	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	levels	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	reduction	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	TNF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	release	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012212	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	alveolar	_	NOUN	_	Number=Sing	_	_	_	_
3	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	markedly	_	ADV	_	_	_	_	_	_
6	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	REF	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	AP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	DNA	_	PROPN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	many	_	ADJ	_	Degree=Pos	_	_	_	_
3	functions	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	alveolar	_	NOUN	_	Degree=Pos	_	_	_	_
7	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	altered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	precursor	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	blood	_	NOUN	_	Number=Sing	_	_	_	_
18	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	reason	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	s	_	X	_	_	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
30	functional	_	ADJ	_	Degree=Pos	_	_	_	_
31	changes	_	NOUN	_	Number=Plur	_	_	_	_
32	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	not	_	PART	_	_	_	_	_	_
34	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
35	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	recently	_	ADV	_	_	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	alveolar	_	NOUN	_	Degree=Pos	_	_	_	_
7	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
8	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	express	_	VERB	_	VerbForm=Inf	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	DNA	_	PROPN	_	Number=Sing	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	Monick	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	M.	_	PROPN	_	Number=Sing	_	_	_	_
21	M.	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	Carter	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	A.	_	PROPN	_	Number=Sing	_	_	_	_
26	B.	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	Gudmundsson	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	G.	_	PROPN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	Geist	_	PROPN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	L.	_	PROPN	_	Number=Sing	_	_	_	_
35	J.	_	PROPN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	Hunninghake	_	PROPN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	G.	_	PROPN	_	Number=Sing	_	_	_	_
41	W.	_	PROPN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	1998	_	NUM	_	NumType=Card	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_

1	Am.	_	PROPN	_	Number=Sing	_	_	_	_
2	J.	_	PROPN	_	Number=Sing	_	_	_	_
3	Physiol.	_	PROPN	_	Number=Sing	_	_	_	_
4	275	_	NUM	_	NumType=Card	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	L389	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	L397	_	NOUN	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	why	_	ADV	_	PronType=Int	_	_	_	_
4	alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
5	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
6	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	express	_	VERB	_	VerbForm=Inf	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	DNA	_	NOUN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	first	_	ADV	_	_	_	_	_	_
18	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	there	_	PRON	_	_	_	_	_	_
21	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	decrease	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	FOS	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	JUN	_	PROPN	_	Number=Sing	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	that	_	PRON	_	PronType=Rel	_	_	_	_
34	make	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	up	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	AP	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	complex	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	however	_	ADV	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	significant	_	ADJ	_	Degree=Pos	_	_	_	_
8	difference	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	amounts	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	REF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	AP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	DNA	_	NOUN	_	Number=Sing	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	by	_	SCONJ	_	_	_	_	_	_
29	altering	_	VERB	_	VerbForm=Ger	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	redox	_	NOUN	_	Number=Sing	_	_	_	_
32	status	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	FOS	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	JUN	_	PROPN	_	Number=Sing	_	_	_	_
37	proteins	_	NOUN	_	Number=Plur	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
42	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
43	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	with	_	ADP	_	_	_	_	_	_
45	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	vitro	_	ADJ	_	Number=Sing	_	_	_	_
6	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	like	_	ADJ	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	amounts	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	REF	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	addition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	REF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	alveolar	_	VERB	_	Degree=Pos	_	_	_	_
13	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	increase	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	AP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	DNA	_	PROPN	_	Number=Sing	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	strongly	_	ADV	_	_	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	process	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	into	_	ADP	_	_	_	_	_	_
13	alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
14	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	loss	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	REF	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	AP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	observation	_	NOUN	_	Number=Sing	_	_	_	_
3	may	_	AUX	_	VerbForm=Fin	_	_	_	_
4	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	part	_	ADJ	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	some	_	DET	_	_	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	functional	_	ADJ	_	Degree=Pos	_	_	_	_
13	differences	_	NOUN	_	Number=Plur	_	_	_	_
14	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	alveolar	_	ADJ	_	Degree=Pos	_	_	_	_
17	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
18	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012213	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Control	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	cycle	_	NOUN	_	Number=Sing	_	_	_	_
5	entry	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	B	_	ADJ	_	Number=Sing	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	Barr	_	PROPN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Infection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Barr	_	PROPN	_	Number=Sing	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	EBV	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	results	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	cycle	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	growth	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	interpret	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	EBV	_	PROPN	_	Number=Sing	_	_	_	_
8	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	assayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	many	_	ADJ	_	Degree=Pos	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	control	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	G0	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	G1	_	NOUN	_	Number=Sing	_	_	_	_
25	phases	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	cycle	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	regulation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	EBV	_	PROPN	_	Number=Sing	_	_	_	_
3	infection	_	NOUN	_	Number=Sing	_	_	_	_
4	most	_	ADJ	_	Degree=Sup	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	changes	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	including	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	early	_	ADJ	_	Degree=Pos	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
15	D2	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	EBV	_	PROPN	_	Number=Sing	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	alteration	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	E2F	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	4	_	NUM	_	NumType=Card	_	_	_	_
33	profile	_	NOUN	_	Number=Sing	_	_	_	_
34	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
35	partly	_	ADV	_	_	_	_	_	_
36	independent	_	ADJ	_	Degree=Pos	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	viral	_	ADJ	_	Degree=Pos	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	expression	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	presumably	_	ADV	_	_	_	_	_	_
43	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	response	_	NOUN	_	Number=Sing	_	_	_	_
46	to	_	ADP	_	_	_	_	_	_
47	signal	_	VERB	_	VerbForm=Inf	_	_	_	_
48	transduction	_	NOUN	_	Number=Sing	_	_	_	_
49	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	when	_	ADV	_	PronType=Int	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	virus	_	NOUN	_	Number=Sing	_	_	_	_
53	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
54	to	_	ADP	_	_	_	_	_	_
55	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
56	receptor	_	NOUN	_	Number=Sing	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	CD21	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	comparing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
8	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	including	_	VERB	_	VerbForm=Ger	_	_	_	_
11	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
13	several	_	ADJ	_	Degree=Pos	_	_	_	_
14	members	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	BCL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	family	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	relative	_	ADJ	_	Degree=Pos	_	_	_	_
27	resistance	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	EBV	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	immortalized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	lines	_	NOUN	_	Number=Plur	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
38	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	low	_	ADJ	_	Degree=Pos	_	_	_	_
41	serum	_	NOUN	_	Number=Sing	_	_	_	_
42	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
43	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	to	_	PART	_	_	_	_	_	_
45	correlate	_	VERB	_	VerbForm=Inf	_	_	_	_
46	with	_	ADP	_	_	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	both	_	CCONJ	_	_	_	_	_	_
50	BCL	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	2	_	NUM	_	NumType=Card	_	_	_	_
53	and	_	CCONJ	_	_	_	_	_	_
54	A20	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	A20	_	NOUN	_	Number=Sing	_	_	_	_
2	can	_	AUX	_	VerbForm=Fin	_	_	_	_
3	be	_	AUX	_	VerbForm=Inf	_	_	_	_
4	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	EBV	_	PROPN	_	Number=Sing	_	_	_	_
22	LMP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Quantitative	_	ADJ	_	Degree=Pos	_	_	_	_
2	assays	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	direct	_	ADJ	_	Degree=Pos	_	_	_	_
6	temporal	_	ADJ	_	Degree=Pos	_	_	_	_
7	relationship	_	NOUN	_	Number=Sing	_	_	_	_
8	between	_	ADP	_	_	_	_	_	_
9	LMP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	levels	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	active	_	ADJ	_	Degree=Pos	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	during	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	time	_	NOUN	_	Number=Sing	_	_	_	_
22	course	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	infection	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012215	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
4	early	_	ADJ	_	Degree=Pos	_	_	_	_
5	response	_	NOUN	_	Number=Sing	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
9	colony	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	normal	_	ADJ	_	Degree=Pos	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	group	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	coordinately	_	ADV	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	protooncogenes	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	cytoskeletal	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
12	matrix	_	NOUN	_	Number=Sing	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	termed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
18	early	_	ADJ	_	Degree=Pos	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	induction	_	NOUN	_	Number=Sing	_	_	_	_
25	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
27	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	growth	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	CSF	_	PROPN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	M	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	CSF	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	proliferate	_	VERB	_	VerbForm=Inf	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	response	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	M	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	CSF	_	NOUN	_	Number=Sing	_	_	_	_
31	but	_	CCONJ	_	_	_	_	_	_
32	require	_	VERB	_	VerbForm=Inf	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	factor	_	NOUN	_	Number=Sing	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Normal	_	ADJ	_	Degree=Pos	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	carefully	_	ADV	_	_	_	_	_	_
8	washed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	incubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	36	_	NUM	_	NumType=Card	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	48	_	NUM	_	NumType=Card	_	_	_	_
16	h	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	fetal	_	ADJ	_	Number=Sing	_	_	_	_
19	bovine	_	NOUN	_	Number=Sing	_	_	_	_
20	serum	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	medium	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	end	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	incubation	_	NOUN	_	Number=Sing	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	resting	_	VERB	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	M	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	CSF	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	RNA	_	PROPN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	analysis	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
25	blotting	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	RNA	_	PROPN	_	Number=Sing	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	control	_	NOUN	_	Number=Sing	_	_	_	_
4	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	low	_	ADV	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	undetectable	_	ADJ	_	Degree=Pos	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	c	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	jun	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	actin	_	NOUN	_	Number=Sing	_	_	_	_
21	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Within	_	ADP	_	_	_	_	_	_
2	15	_	NUM	_	NumType=Card	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	30	_	NUM	_	NumType=Card	_	_	_	_
5	min	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	addition	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	M	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	CSF	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	however	_	ADV	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	there	_	PRON	_	_	_	_	_	_
16	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
19	coordinate	_	ADJ	_	Degree=Pos	_	_	_	_
20	induction	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	c-jun	_	NOUN	_	Degree=Pos	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	very	_	ADV	_	_	_	_	_	_
7	transient	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	60	_	NUM	_	NumType=Card	_	_	_	_
14	min	_	NOUN	_	Number=Plur	_	_	_	_
15	after	_	ADP	_	_	_	_	_	_
16	M	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	CSF	_	NOUN	_	Number=Sing	_	_	_	_
19	addition	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	actin	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	more	_	ADV	_	_	_	_	_	_
14	sustained	_	ADJ	_	Degree=Pos	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	at	_	ADP	_	_	_	_	_	_
25	24	_	NUM	_	NumType=Card	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	48	_	NUM	_	NumType=Card	_	_	_	_
28	h	_	NOUN	_	Number=Plur	_	_	_	_
29	after	_	ADP	_	_	_	_	_	_
30	M	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	CSF	_	NOUN	_	Number=Sing	_	_	_	_
33	addition	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	myelomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	hck	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	simultaneously	_	ADV	_	_	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	other	_	ADJ	_	Degree=Pos	_	_	_	_
18	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
19	early	_	ADJ	_	Degree=Pos	_	_	_	_
20	response	_	NOUN	_	Number=Sing	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
4	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
5	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
6	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	block	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	any	_	DET	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	fact	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	super	_	ADV	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	c	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	jun	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	hck	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	run	_	NOUN	_	Number=Sing	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	hck	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	actin	_	NOUN	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	normal	_	ADJ	_	Degree=Pos	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	M	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	CSF	_	NOUN	_	Number=Sing	_	_	_	_
10	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
12	early	_	ADJ	_	Degree=Pos	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	without	_	SCONJ	_	_	_	_	_	_
16	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	genes	_	NOUN	_	Number=Plur	_	_	_	_
3	may	_	AUX	_	VerbForm=Fin	_	_	_	_
4	then	_	ADV	_	PronType=Dem	_	_	_	_
5	play	_	VERB	_	VerbForm=Inf	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	altering	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	physiologic	_	ADJ	_	Degree=Pos	_	_	_	_
12	status	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	CSF	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012216	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	active	_	ADJ	_	Degree=Pos	_	_	_	_
3	v-abl	_	NOUN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	blocks	_	NOUN	_	Number=Plur	_	_	_	_
8	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
9	light	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	chain	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Lymphoid	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	Abelson	_	PROPN	_	Number=Sing	_	_	_	_
6	murine	_	PROPN	_	Number=Sing	_	_	_	_
7	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	provided	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	one	_	NUM	_	NumType=Card	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	classic	_	ADJ	_	Degree=Pos	_	_	_	_
15	models	_	NOUN	_	Number=Plur	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	study	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	early	_	ADJ	_	Degree=Pos	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	development	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
26	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Most	_	ADJ	_	Degree=Sup	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	rearranged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
8	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	chain	_	NOUN	_	Number=Sing	_	_	_	_
11	locus	_	NOUN	_	Number=Sing	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	light	_	NOUN	_	Degree=Pos	_	_	_	_
16	chain	_	NOUN	_	Number=Sing	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	active	_	ADJ	_	Degree=Pos	_	_	_	_
23	v-abl	_	NOUN	_	Number=Sing	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	interferes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
29	step	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	test	_	VERB	_	VerbForm=Inf	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	light	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	chain	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	structure	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	temperature	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
21	mutants	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	Abelson	_	PROPN	_	Number=Sing	_	_	_	_
25	virus	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	derivatives	_	NOUN	_	Number=Plur	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	survive	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	at	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	nonpermissive	_	ADJ	_	Degree=Pos	_	_	_	_
34	temperature	_	NOUN	_	Number=Sing	_	_	_	_
35	because	_	SCONJ	_	_	_	_	_	_
36	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
37	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	human	_	ADJ	_	Degree=Pos	_	_	_	_
40	BCL	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	2	_	NUM	_	NumType=Card	_	_	_	_
43	gene	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	DET	_	_	_	_	_	_
5	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	v-abl	_	ADJ	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	triggers	_	VERB	_	Number=Plur	_	_	_	_
13	high	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	frequency	_	NOUN	_	Number=Sing	_	_	_	_
16	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	lambda	_	NOUN	_	Number=Sing	_	_	_	_
21	light	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	chain	_	NOUN	_	Number=Sing	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	events	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	increases	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	RAG	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	RAG	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	RNAs	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	increases	_	NOUN	_	Number=Plur	_	_	_	_
3	occur	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	absence	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	v-abl	_	ADJ	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	documented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	accompanying	_	NOUN	_	Degree=Pos	_	_	_	_
6	paper	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	Klug	_	PROPN	_	Number=Sing	_	_	_	_
9	et	_	X	_	_	_	_	_	_
10	al.	_	X	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
13	issue	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	active	_	ADJ	_	Degree=Pos	_	_	_	_
18	v-abl	_	NOUN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	also	_	ADV	_	_	_	_	_	_
21	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	rel	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	kappa	_	NOUN	_	Number=Sing	_	_	_	_
37	intron	_	NOUN	_	Number=Sing	_	_	_	_
38	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	data	_	NOUN	_	Number=Sing	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	v-abl	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	specifically	_	ADV	_	_	_	_	_	_
10	interferes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	light	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	chain	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	SCONJ	_	_	_	_	_	_
18	suppressing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	at	_	ADV	_	_	_	_	_	_
20	least	_	ADV	_	Degree=Sup	_	_	_	_
21	two	_	NUM	_	NumType=Card	_	_	_	_
22	pathways	_	NOUN	_	Number=Plur	_	_	_	_
23	essential	_	ADJ	_	Degree=Pos	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	stage	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	that	_	SCONJ	_	_	_	_	_	_
35	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
36	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	important	_	ADJ	_	Degree=Pos	_	_	_	_
39	in	_	SCONJ	_	_	_	_	_	_
40	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
41	RAG	_	NOUN	_	Number=Sing	_	_	_	_
42	gene	_	NOUN	_	Number=Sing	_	_	_	_
43	expression	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012219	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
2	downregulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IgH	_	NOUN	_	Number=Sing	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	'	_	PUNCT	_	_	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	plasmacytoma	_	NOUN	_	Number=Sing	_	_	_	_
15	x	_	NOUN	_	_	_	_	_	_
16	fibroblast	_	ADJ	_	Degree=Pos	_	_	_	_
17	environment	_	NOUN	_	Number=Sing	_	_	_	_
18	:	_	PUNCT	_	_	_	_	_	_
19	implications	_	NOUN	_	Number=Plur	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	dysregulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	translocated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	c-myc	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
4	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
5	chain	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	IgH	_	ADJ	_	Degree=Pos	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	B	_	NUM	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	intronic	_	ADJ	_	Degree=Pos	_	_	_	_
22	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	additional	_	ADJ	_	Degree=Pos	_	_	_	_
25	B	_	NOUN	_	Degree=Pos	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	specific	_	ADJ	_	Degree=Pos	_	_	_	_
29	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
30	elements	_	NOUN	_	Number=Plur	_	_	_	_
31	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	recently	_	ADV	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	3	_	NUM	_	NumType=Card	_	_	_	_
36	'	_	PUNCT	_	_	_	_	_	_
37	end	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	IgH	_	PROPN	_	Number=Sing	_	_	_	_
41	locus	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	latter	_	ADJ	_	Degree=Pos	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IgH	_	PROPN	_	Number=Sing	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	'	_	PUNCT	_	_	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	particular	_	ADJ	_	Degree=Pos	_	_	_	_
16	interest	_	NOUN	_	Number=Sing	_	_	_	_
17	:	_	PUNCT	_	_	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	1	_	X	_	_	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	B	_	DET	_	NumType=Card	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	specific	_	ADJ	_	Degree=Pos	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	active	_	ADJ	_	Degree=Pos	_	_	_	_
29	only	_	ADV	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	late	_	ADJ	_	Degree=Pos	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	development	_	NOUN	_	Number=Sing	_	_	_	_
35	;	_	PUNCT	_	_	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	2	_	X	_	_	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	rodent	_	ADJ	_	Degree=Pos	_	_	_	_
41	plasmacytomas	_	NOUN	_	Number=Plur	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	some	_	DET	_	_	_	_	_	_
45	human	_	ADJ	_	Degree=Pos	_	_	_	_
46	Burkitt	_	NOUN	_	Number=Sing	_	_	_	_
47	's	_	PART	_	_	_	_	_	_
48	lymphomas	_	NOUN	_	Number=Plur	_	_	_	_
49	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
50	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
51	part	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
54	locus	_	NOUN	_	Number=Sing	_	_	_	_
55	control	_	NOUN	_	Number=Sing	_	_	_	_
56	region	_	NOUN	_	Number=Sing	_	_	_	_
57	(	_	PUNCT	_	_	_	_	_	_
58	LCR	_	NOUN	_	Number=Sing	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	that	_	PRON	_	PronType=Rel	_	_	_	_
61	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
62	involved	_	ADJ	_	Degree=Pos	_	_	_	_
63	in	_	ADP	_	_	_	_	_	_
64	deregulation	_	NOUN	_	Number=Sing	_	_	_	_
65	of	_	ADP	_	_	_	_	_	_
66	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
67	c-myc	_	PROPN	_	Number=Sing	_	_	_	_
68	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
69	as	_	ADP	_	_	_	_	_	_
70	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
71	result	_	NOUN	_	Number=Sing	_	_	_	_
72	of	_	ADP	_	_	_	_	_	_
73	translocation	_	NOUN	_	Number=Sing	_	_	_	_
74	into	_	ADP	_	_	_	_	_	_
75	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
76	IgH	_	PROPN	_	Number=Sing	_	_	_	_
77	locus	_	NOUN	_	Number=Sing	_	_	_	_
78	;	_	PUNCT	_	_	_	_	_	_
79	and	_	CCONJ	_	_	_	_	_	_
80	(	_	PUNCT	_	_	_	_	_	_
81	3	_	X	_	_	_	_	_	_
82	)	_	PUNCT	_	_	_	_	_	_
83	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
84	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
85	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
86	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
87	in	_	ADP	_	_	_	_	_	_
88	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
89	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
90	that	_	PRON	_	PronType=Rel	_	_	_	_
91	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
92	Ig	_	NOUN	_	Degree=Pos	_	_	_	_
93	gene	_	NOUN	_	Number=Sing	_	_	_	_
94	class	_	NOUN	_	Number=Sing	_	_	_	_
95	switch	_	NOUN	_	Number=Sing	_	_	_	_
96	recombination	_	NOUN	_	Number=Sing	_	_	_	_
97	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	somatic	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
8	approach	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	genetically	_	ADV	_	_	_	_	_	_
11	analyse	_	VERB	_	VerbForm=Inf	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	IgH	_	PROPN	_	Number=Sing	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	'	_	PUNCT	_	_	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	mouse	_	NOUN	_	Number=Sing	_	_	_	_
3	MPC11	_	NUM	_	Number=Sing	_	_	_	_
4	plasmacytoma	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	IgH	_	PROPN	_	Degree=Pos	_	_	_	_
11	3	_	NUM	_	NumType=Card	_	_	_	_
12	'	_	PUNCT	_	_	_	_	_	_
13	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	active	_	ADJ	_	Degree=Pos	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	fused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	Ig	_	PROPN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	extinguished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	at	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	level	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	MPC11	_	NOUN	_	Number=Sing	_	_	_	_
8	plasmacytoma	_	NOUN	_	Number=Sing	_	_	_	_
9	x	_	NOUN	_	_	_	_	_	_
10	fibroblast	_	NOUN	_	Number=Sing	_	_	_	_
11	environment	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IgH	_	PROPN	_	Number=Sing	_	_	_	_
15	3	_	NUM	_	NumType=Card	_	_	_	_
16	'	_	PUNCT	_	_	_	_	_	_
17	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	transcriptionally	_	ADV	_	_	_	_	_	_
20	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	DET	_	_	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	several	_	ADJ	_	Degree=Pos	_	_	_	_
9	B	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	essential	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	IgH	_	NOUN	_	Degree=Pos	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	'	_	PUNCT	_	_	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	lacking	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	which	_	PRON	_	PronType=Int	_	_	_	_
28	may	_	AUX	_	VerbForm=Fin	_	_	_	_
29	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	'	_	PUNCT	_	_	_	_	_	_
32	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
33	inactivity	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	although	_	SCONJ	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	binding	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	repressors	_	NOUN	_	Number=Plur	_	_	_	_
40	can	_	AUX	_	VerbForm=Fin	_	_	_	_
41	not	_	PART	_	_	_	_	_	_
42	be	_	AUX	_	VerbForm=Inf	_	_	_	_
43	excluded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	high	_	ADJ	_	Degree=Pos	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	level	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	c-myc	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	characteristic	_	ADJ	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	parental	_	ADJ	_	Number=Sing	_	_	_	_
14	MPC11	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	t	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	12	_	NUM	_	NumType=Card	_	_	_	_
21	;	_	PUNCT	_	_	_	_	_	_
22	15	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	translocation	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	down	_	ADV	_	_	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	hybrids	_	NOUN	_	Number=Plur	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	unfused	_	ADJ	_	Degree=Pos	_	_	_	_
37	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IgH	_	PROPN	_	Number=Sing	_	_	_	_
7	3	_	NUM	_	NumType=Card	_	_	_	_
8	'	_	PUNCT	_	_	_	_	_	_
9	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	multifactorial	_	ADJ	_	Degree=Pos	_	_	_	_
13	process	_	NOUN	_	Number=Sing	_	_	_	_
14	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	several	_	ADJ	_	Degree=Pos	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012224	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	critical	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	CD14	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	CD14	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	membrane	_	NOUN	_	Number=Sing	_	_	_	_
5	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	specifically	_	ADV	_	_	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	markedly	_	ADV	_	_	_	_	_	_
18	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	during	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	process	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	study	_	VERB	_	VerbForm=Inf	_	_	_	_
5	CD14	_	PROPN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	CD14	_	PROPN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	partial	_	ADJ	_	Degree=Pos	_	_	_	_
18	EcoRI	_	PROPN	_	Number=Sing	_	_	_	_
19	digested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
21	5	_	NUM	_	NumType=Card	_	_	_	_
22	library	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	5.5	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kilobase	_	NOUN	_	Number=Sing	_	_	_	_
5	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
6	clone	_	NOUN	_	Number=Sing	_	_	_	_
7	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	full	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	length	_	NOUN	_	Number=Sing	_	_	_	_
12	CD14	_	PROPN	_	Number=Sing	_	_	_	_
13	coding	_	NOUN	_	Number=Sing	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	4.2	_	NUM	_	NumType=Card	_	_	_	_
17	kilobases	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	5	_	NUM	_	NumType=Card	_	_	_	_
20	'-	_	PUNCT	_	_	_	_	_	_
21	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
22	sequence	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	major	_	ADJ	_	Degree=Pos	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	one	_	NUM	_	NumType=Card	_	_	_	_
5	minor	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	start	_	NOUN	_	Number=Sing	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	101	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	130	_	NUM	_	NumType=Card	_	_	_	_
14	base	_	NOUN	_	Number=Sing	_	_	_	_
15	pairs	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	bp	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	upstream	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	respectively	_	ADV	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	translation	_	NOUN	_	Number=Sing	_	_	_	_
27	start	_	NOUN	_	Number=Sing	_	_	_	_
28	ATG	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	fragment	_	NOUN	_	Number=Sing	_	_	_	_
4	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	128	_	NUM	_	NumType=Card	_	_	_	_
6	bp	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
9	sequence	_	NOUN	_	Number=Sing	_	_	_	_
10	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	strong	_	ADJ	_	Degree=Pos	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	CD14	_	PROPN	_	Number=Sing	_	_	_	_
21	positive	_	ADJ	_	Degree=Pos	_	_	_	_
22	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	line	_	NOUN	_	Number=Sing	_	_	_	_
25	Mono	_	PROPN	_	Number=Sing	_	_	_	_
26	Mac	_	PROPN	_	Number=Sing	_	_	_	_
27	6	_	NUM	_	NumType=Card	_	_	_	_
28	as	_	SCONJ	_	_	_	_	_	_
29	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	nonmonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	lines	_	NOUN	_	Number=Plur	_	_	_	_
35	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	REX	_	PROPN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Four	_	NUM	_	NumType=Card	_	_	_	_
2	regions	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	fragment	_	NOUN	_	Number=Sing	_	_	_	_
7	interact	_	VERB	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	bound	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	three	_	NUM	_	NumType=Card	_	_	_	_
8	different	_	ADJ	_	Degree=Pos	_	_	_	_
9	regions	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	CD14	_	PROPN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	major	_	ADJ	_	Degree=Pos	_	_	_	_
5	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	-	_	SYM	_	_	_	_	_	_
10	110	_	NUM	_	NumType=Card	_	_	_	_
11	bp	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	tissue	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
22	results	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	together	_	ADV	_	_	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
27	experiments	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	that	_	SCONJ	_	_	_	_	_	_
31	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
32	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	critical	_	ADJ	_	Degree=Pos	_	_	_	_
35	role	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	tissue	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	specific	_	ADJ	_	Degree=Pos	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	CD14	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	CD14	_	PROPN	_	Number=Sing	_	_	_	_
2	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
3	site	_	NOUN	_	Number=Sing	_	_	_	_
4	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
5	bound	_	VERB	_	Degree=Pos	_	_	_	_
6	preferentially	_	ADV	_	_	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	105	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kDa	_	NOUN	_	Number=Sing	_	_	_	_
12	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
13	species	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	present	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
20	relative	_	ADJ	_	Degree=Pos	_	_	_	_
21	levels	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
24	than	_	ADP	_	_	_	_	_	_
25	non-monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	modification	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	such	_	ADJ	_	Degree=Pos	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	may	_	AUX	_	VerbForm=Fin	_	_	_	_
39	explain	_	VERB	_	VerbForm=Inf	_	_	_	_
40	how	_	ADV	_	PronType=Int	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
43	site	_	NOUN	_	Number=Sing	_	_	_	_
44	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
46	specific	_	ADJ	_	Degree=Pos	_	_	_	_
47	promoter	_	NOUN	_	Number=Sing	_	_	_	_
48	activity	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012226	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Redox	_	NOUN	_	Number=Sing	_	_	_	_
2	signals	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Accumulating	_	VERB	_	VerbForm=Ger	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	number	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	laboratories	_	NOUN	_	Number=Plur	_	_	_	_
8	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	recently	_	ADV	_	_	_	_	_	_
10	indicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	alterations	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	redox	_	NOUN	_	Number=Sing	_	_	_	_
25	homeostasis	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	may	_	AUX	_	VerbForm=Fin	_	_	_	_
29	play	_	VERB	_	VerbForm=Inf	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	important	_	ADJ	_	Degree=Pos	_	_	_	_
32	role	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
35	immune	_	ADJ	_	Degree=Pos	_	_	_	_
36	function	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
7	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
9	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	number	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	responses	_	NOUN	_	Number=Plur	_	_	_	_
22	including	_	VERB	_	VerbForm=Ger	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	6	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	8	_	NUM	_	NumType=Card	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	several	_	ADJ	_	Degree=Pos	_	_	_	_
37	T	_	NUM	_	NumType=Card	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	surface	_	NOUN	_	Number=Sing	_	_	_	_
40	receptors	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Diminished	_	ADJ	_	Degree=Pos	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	aging	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	might	_	AUX	_	VerbForm=Fin	_	_	_	_
26	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
27	during	_	ADP	_	_	_	_	_	_
28	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
29	senescence	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	aberrancies	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	immunopathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	diseases	_	NOUN	_	Number=Plur	_	_	_	_
18	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
19	immune	_	ADJ	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	processes	_	NOUN	_	Number=Plur	_	_	_	_
23	such	_	ADJ	_	Degree=Pos	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	atherosclerosis	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	HIV	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	infection	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
8	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
9	species	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	ROS	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	integratory	_	ADJ	_	Degree=Pos	_	_	_	_
16	secondary	_	ADJ	_	Degree=Pos	_	_	_	_
17	messenger	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	divergent	_	ADJ	_	Degree=Pos	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	signals	_	NOUN	_	Number=Plur	_	_	_	_
23	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
25	complicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	fact	_	NOUN	_	Number=Sing	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	various	_	ADJ	_	Degree=Pos	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	lines	_	NOUN	_	Number=Plur	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
36	blood	_	NOUN	_	Number=Sing	_	_	_	_
37	T	_	NOUN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	markedly	_	ADV	_	_	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	levels	_	NOUN	_	Number=Plur	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	NF	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
48	activation	_	NOUN	_	Number=Sing	_	_	_	_
49	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	by	_	ADP	_	_	_	_	_	_
51	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
52	stress	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	proposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	pathways	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	indirect	_	ADJ	_	Degree=Pos	_	_	_	_
15	evidence	_	NOUN	_	Number=Sing	_	_	_	_
16	provided	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	experiments	_	NOUN	_	Number=Plur	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
24	active	_	ADJ	_	Degree=Pos	_	_	_	_
25	NF	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	formation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	complete	_	ADJ	_	Degree=Pos	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	at	_	ADV	_	_	_	_	_	_
10	least	_	ADV	_	Degree=Sup	_	_	_	_
11	two	_	NUM	_	NumType=Card	_	_	_	_
12	signals	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	one	_	NUM	_	NumType=Card	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	increase	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
21	calcium	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	one	_	NUM	_	NumType=Card	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	enzymatic	_	ADJ	_	Degree=Pos	_	_	_	_
27	processes	_	NOUN	_	Number=Plur	_	_	_	_
28	including	_	VERB	_	VerbForm=Ger	_	_	_	_
29	kinases	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Similarly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
4	evidence	_	NOUN	_	Number=Sing	_	_	_	_
5	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	full	_	ADJ	_	Degree=Pos	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	dual	_	ADJ	_	Degree=Pos	_	_	_	_
15	signals	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	H2O2	_	NOUN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	ROS	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	signals	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	functional	_	ADJ	_	Degree=Pos	_	_	_	_
15	responses	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
18	two	_	NUM	_	NumType=Card	_	_	_	_
19	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	reviewed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	response	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	redox	_	NOUN	_	Number=Sing	_	_	_	_
32	changes	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	T	_	PROPN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Data	_	NOUN	_	Number=Sing	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	presented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	suggest	_	VERB	_	VerbForm=Inf	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	redox	_	NOUN	_	Number=Sing	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	immune	_	ADJ	_	VerbForm=Inf	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	related	_	ADJ	_	Degree=Pos	_	_	_	_
23	diseases	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	aging	_	VERB	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012227	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	PGG	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	glucan	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	1,3	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	glucan	_	ADJ	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
18	burst	_	NOUN	_	Number=Sing	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	microbicidal	_	ADJ	_	Degree=Pos	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	like	_	ADJ	_	Degree=Pos	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	human	_	ADJ	_	Degree=Pos	_	_	_	_
36	PMN	_	NOUN	_	Number=Sing	_	_	_	_
37	:	_	PUNCT	_	_	_	_	_	_
38	evidence	_	NOUN	_	Number=Sing	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	glycosphingolipid	_	ADJ	_	Degree=Pos	_	_	_	_
42	beta	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	1,3	_	NUM	_	NumType=Card	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	glucan	_	ADJ	_	Degree=Pos	_	_	_	_
49	receptor	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	PGG	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Glucan	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	soluble	_	ADJ	_	Number=Sing	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	1,6	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	branched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	1,3	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	glucose	_	NOUN	_	Number=Sing	_	_	_	_
22	homopolymer	_	NOUN	_	Number=Sing	_	_	_	_
23	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	wall	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	yeast	_	NOUN	_	Number=Sing	_	_	_	_
31	Saccharomyces	_	PROPN	_	Number=Plur	_	_	_	_
32	cerevisiae	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	immunomodulator	_	NOUN	_	Number=Sing	_	_	_	_
37	which	_	PRON	_	PronType=Rel	_	_	_	_
38	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	leukocyte	_	ADJ	_	Number=Sing	_	_	_	_
40	anti	_	X	_	_	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	infective	_	ADJ	_	Degree=Pos	_	_	_	_
43	activity	_	NOUN	_	Number=Sing	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	enhances	_	VERB	_	Number=Plur	_	_	_	_
46	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	megakaryocyte	_	NOUN	_	Degree=Pos	_	_	_	_
49	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
50	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Incubation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	whole	_	ADJ	_	Degree=Pos	_	_	_	_
5	blood	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	PGG	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Glucan	_	PROPN	_	Degree=Pos	_	_	_	_
10	significantly	_	ADV	_	_	_	_	_	_
11	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
14	burst	_	NOUN	_	Number=Sing	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	subsequently	_	ADV	_	_	_	_	_	_
18	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	blood	_	NOUN	_	Number=Sing	_	_	_	_
20	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	particulate	_	ADJ	_	Degree=Pos	_	_	_	_
26	activators	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	dose	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
32	manner	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	leukocyte	_	ADJ	_	Number=Sing	_	_	_	_
37	microbicidal	_	ADJ	_	Degree=Pos	_	_	_	_
38	activity	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	evidence	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
6	production	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	under	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	conditions	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	PGG	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Glucan	_	PROPN	_	Number=Sing	_	_	_	_
10	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	like	_	ADP	_	Degree=Pos	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	purified	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	3H-PGG	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	Glucan	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	membranes	_	NOUN	_	Number=Plur	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	concentration	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	saturable	_	ADJ	_	Degree=Pos	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	high	_	ADJ	_	Degree=Pos	_	_	_	_
22	affinity	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	Kd	_	PROPN	_	Number=Sing	_	_	_	_
25	approximately	_	ADV	_	_	_	_	_	_
26	6	_	NUM	_	NumType=Card	_	_	_	_
27	nM	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
3	antibody	_	NOUN	_	Number=Sing	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	glycosphingolipid	_	ADJ	_	Degree=Pos	_	_	_	_
8	lactosylceramide	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	able	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	like	_	ADJ	_	Degree=Pos	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	PGG	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	Glucan	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	ligand	_	NOUN	_	Number=Sing	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	data	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	including	_	VERB	_	VerbForm=Ger	_	_	_	_
33	polysaccharide	_	NOUN	_	Degree=Pos	_	_	_	_
34	specificity	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	that	_	SCONJ	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	PGG	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	Glucan	_	ADJ	_	Degree=Pos	_	_	_	_
42	binding	_	NOUN	_	Number=Sing	_	_	_	_
43	moiety	_	NOUN	_	Number=Sing	_	_	_	_
44	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
45	lactosylceramide	_	ADJ	_	Degree=Pos	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	PGG	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Glucan	_	ADJ	_	Degree=Pos	_	_	_	_
8	enhances	_	VERB	_	Number=Plur	_	_	_	_
9	neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
10	anti-microbial	_	ADJ	_	Degree=Pos	_	_	_	_
11	functions	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	interaction	_	NOUN	_	Number=Sing	_	_	_	_
15	between	_	ADP	_	_	_	_	_	_
16	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	beta	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	glucan	_	ADJ	_	Degree=Pos	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	glycosphingolipid	_	ADJ	_	Degree=Pos	_	_	_	_
28	lactosylceramide	_	NOUN	_	Number=Sing	_	_	_	_
29	present	_	NOUN	_	Number=Sing	_	_	_	_
30	at	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	surface	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012228	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cloning	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	novel	_	NOUN	_	Number=Sing	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Chicken	_	NOUN	_	Number=Sing	_	_	_	_
2	NF	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	M	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	either	_	CCONJ	_	_	_	_	_	_
12	c	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	Myb	_	NOUN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	v-Myb	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	active	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	combinatorial	_	ADJ	_	Degree=Pos	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	specific	_	ADJ	_	Degree=Pos	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	types	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	such	_	ADJ	_	Degree=Pos	_	_	_	_
37	as	_	ADP	_	_	_	_	_	_
38	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
39	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	humans	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	similar	_	ADJ	_	Degree=Pos	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
10	members	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	CCAAT	_	PROPN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	C	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	EBP	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	family	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
27	regulators	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	especially	_	ADV	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	homolog	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	chicken	_	NOUN	_	Number=Sing	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	M	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	beta	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	NF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	IL6	_	NOUN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	IL6	_	PROPN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	variety	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	nonmyeloid	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	types	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	strongly	_	ADV	_	_	_	_	_	_
20	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	making	_	VERB	_	VerbForm=Ger	_	_	_	_
28	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	unlikely	_	ADJ	_	Degree=Pos	_	_	_	_
31	candidate	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	have	_	VERB	_	VerbForm=Inf	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	exclusive	_	ADJ	_	Degree=Pos	_	_	_	_
36	role	_	NOUN	_	Number=Sing	_	_	_	_
37	as	_	ADP	_	_	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	combinatorial	_	ADJ	_	Degree=Pos	_	_	_	_
40	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
41	switch	_	NOUN	_	Number=Sing	_	_	_	_
42	during	_	ADP	_	_	_	_	_	_
43	myelopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	human	_	ADJ	_	Degree=Pos	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	reverse	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	PCR	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	approach	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	set	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	primers	_	NOUN	_	Number=Plur	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	DNA	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	binding	_	VERB	_	Number=Sing	_	_	_	_
22	domains	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	highly	_	ADV	_	_	_	_	_	_
25	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
26	members	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
30	family	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
33	regulators	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
36	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
37	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	novel	_	NOUN	_	Number=Sing	_	_	_	_
40	human	_	ADJ	_	Degree=Pos	_	_	_	_
41	gene	_	NOUN	_	Number=Sing	_	_	_	_
42	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	member	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
48	gene	_	NOUN	_	Number=Sing	_	_	_	_
49	family	_	NOUN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
52	as	_	ADP	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	human	_	ADJ	_	Degree=Pos	_	_	_	_
55	homolog	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	CRP1	_	PROPN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	1.2	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kb	_	NOUN	_	Number=Sing	_	_	_	_
5	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
6	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
7	full	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	length	_	NOUN	_	Number=Sing	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	promyelocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	late	_	ADJ	_	Degree=Pos	_	_	_	_
21	myeloblast	_	ADV	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	lambda	_	NOUN	_	Number=Sing	_	_	_	_
25	gt11	_	NOUN	_	Number=Sing	_	_	_	_
26	library	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
8	clones	_	NOUN	_	Number=Plur	_	_	_	_
9	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	presence	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	two	_	NUM	_	NumType=Card	_	_	_	_
14	exons	_	NOUN	_	Number=Plur	_	_	_	_
15	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
21	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
22	mass	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	32	_	NUM	_	NumType=Card	_	_	_	_
25	kDa	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	pI	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	9.5	_	NUM	_	NumType=Card	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Primer	_	ADJ	_	Number=Sing	_	_	_	_
2	extension	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
8	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
9	detected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	single	_	ADJ	_	Degree=Pos	_	_	_	_
12	major	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	start	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	approximately	_	ADV	_	_	_	_	_	_
17	200	_	NUM	_	NumType=Card	_	_	_	_
18	bp	_	NOUN	_	Number=Sing	_	_	_	_
19	upstream	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	start	_	NOUN	_	Number=Sing	_	_	_	_
23	codon	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	putative	_	ADJ	_	Degree=Pos	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	area	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	similar	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	several	_	ADJ	_	Degree=Pos	_	_	_	_
11	other	_	ADJ	_	Degree=Pos	_	_	_	_
12	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	SCONJ	_	_	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
21	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	no	_	DET	_	_	_	_	_	_
23	TATAAA	_	NOUN	_	Number=Sing	_	_	_	_
24	box	_	NOUN	_	Number=Sing	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	number	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	purine	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	rich	_	ADJ	_	Degree=Pos	_	_	_	_
33	stretches	_	NOUN	_	Number=Plur	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
36	sites	_	NOUN	_	Number=Plur	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	factors	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	Ets	_	NOUN	_	Number=Sing	_	_	_	_
43	family	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
46	regulators	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	analyses	_	NOUN	_	Number=Plur	_	_	_	_
4	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	highly	_	ADV	_	_	_	_	_	_
7	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	pattern	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	strongest	_	ADJ	_	Degree=Sup	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	promyelocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	late	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	myeloblast	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	like	_	ADJ	_	Degree=Pos	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	lines	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	using	_	VERB	_	VerbForm=Ger	_	_	_	_
7	rabbit	_	NOUN	_	Number=Sing	_	_	_	_
8	anti-C/EBP	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
11	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
12	raised	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	against	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	N	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	terminal	_	ADJ	_	Number=Sing	_	_	_	_
18	portion	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	amino	_	PROPN	_	Number=Sing	_	_	_	_
25	acids	_	NOUN	_	Number=Plur	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	115	_	NUM	_	NumType=Card	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
35	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	32	_	NUM	_	NumType=Card	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kDa	_	NOUN	_	Number=Sing	_	_	_	_
40	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
41	phosphoprotein	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	strong	_	ADJ	_	Degree=Pos	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	double	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	consensus	_	NOUN	_	Number=Sing	_	_	_	_
19	C	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	EBP	_	NOUN	_	Number=Sing	_	_	_	_
22	sites	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
7	sense	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	antisense	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	constructs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	together	_	ADV	_	_	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
15	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
16	reporter	_	NOUN	_	Number=Sing	_	_	_	_
17	vectors	_	NOUN	_	Number=Plur	_	_	_	_
18	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	c-mim	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	myeloperoxidase	_	NOUN	_	Number=Sing	_	_	_	_
28	promoters	_	NOUN	_	Number=Plur	_	_	_	_
29	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	role	_	NOUN	_	Number=Sing	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
36	transcription	_	NOUN	_	Number=Sing	_	_	_	_
37	factor	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	regulation	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	subset	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	cell	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	specific	_	ADJ	_	Degree=Pos	_	_	_	_
50	genes	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	tranfection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	promyelocyte	_	NOUN	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	line	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	NB4	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	plasmid	_	NOUN	_	_	_	_	_	_
18	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	growth	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	sevenfold	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	while	_	SCONJ	_	_	_	_	_	_
25	antisense	_	ADJ	_	Number=Sing	_	_	_	_
26	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
29	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	fivefold	_	VERB	_	Degree=Pos	_	_	_	_
32	decrease	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
35	growth	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012232	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	Ets	_	NOUN	_	Number=Plur	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	related	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	Elf	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	product	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	Rb	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	phosphoprotein	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	cycle	_	NOUN	_	Number=Sing	_	_	_	_
16	progression	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Elf	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_

1	Ets	_	NOUN	_	Number=Sing	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	Elf	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	motif	_	NOUN	_	Number=Sing	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	highly	_	ADV	_	_	_	_	_	_
19	related	_	ADJ	_	Degree=Pos	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	Rb	_	PROPN	_	Number=Sing	_	_	_	_
23	binding	_	VERB	_	Number=Sing	_	_	_	_
24	sites	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	several	_	ADJ	_	Degree=Pos	_	_	_	_
27	viral	_	ADJ	_	Degree=Pos	_	_	_	_
28	oncoproteins	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	binds	_	NOUN	_	Number=Plur	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	pocket	_	NOUN	_	Number=Sing	_	_	_	_
34	region	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	Rb	_	PROPN	_	Number=Sing	_	_	_	_
37	both	_	CCONJ	_	_	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	vitro	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	vivo	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Elf	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	binds	_	NOUN	_	Number=Plur	_	_	_	_
5	exclusively	_	ADV	_	_	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	underphosphorylated	_	ADJ	_	Degree=Pos	_	_	_	_
9	form	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Rb	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	fails	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	Rb	_	PROPN	_	Number=Sing	_	_	_	_
18	mutants	_	NOUN	_	Number=Plur	_	_	_	_
19	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	patients	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Co-	_	PUNCT	_	_	_	_	_	_
2	immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	association	_	NOUN	_	Number=Sing	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	Elf	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Rb	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	SCONJ	_	_	_	_	_	_
14	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	normal	_	ADJ	_	Degree=Pos	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Rb	_	NOUN	_	Number=Sing	_	_	_	_
10	results	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	release	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	Elf	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	temporally	_	ADV	_	_	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	Elf	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	defective	_	ADJ	_	Degree=Pos	_	_	_	_
7	form	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Rb	_	PROPN	_	Number=Sing	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	Elf	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Rb	_	PROPN	_	Number=Sing	_	_	_	_
6	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	specifically	_	ADV	_	_	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	lineage	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	Ets	_	NOUN	_	Number=Sing	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	regulated	_	VERB	_	Degree=Pos	_	_	_	_
3	interaction	_	NOUN	_	Number=Sing	_	_	_	_
4	may	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	important	_	ADJ	_	Degree=Pos	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	coordination	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	lineage	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	effector	_	NOUN	_	Number=Sing	_	_	_	_
15	functions	_	NOUN	_	Number=Plur	_	_	_	_
16	such	_	ADJ	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
19	production	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	cycle	_	NOUN	_	Number=Sing	_	_	_	_
23	progression	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012238	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	cytomegalovirus	_	NOUN	_	Number=Sing	_	_	_	_
3	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	8	_	NUM	_	NumType=Card	_	_	_	_
7	production	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	line	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	THP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	through	_	SCONJ	_	_	_	_	_	_
20	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	concurrently	_	ADV	_	_	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	AP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
33	sites	_	NOUN	_	Number=Plur	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	8	_	NUM	_	NumType=Card	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Cytomegalovirus	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	CMV	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	infection	_	NOUN	_	Number=Sing	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	8	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	8	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	line	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	THP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	8	_	NUM	_	NumType=Card	_	_	_	_
34	secretion	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	functional	_	ADJ	_	Degree=Pos	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	8	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	both	_	DET	_	_	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	binding	_	VERB	_	Number=Sing	_	_	_	_
24	elements	_	NOUN	_	Number=Plur	_	_	_	_
25	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	involved	_	ADJ	_	Degree=Pos	_	_	_	_
27	in	_	SCONJ	_	_	_	_	_	_
28	conferring	_	VERB	_	VerbForm=Ger	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	CMV	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
4	mobility	_	NOUN	_	Number=Sing	_	_	_	_
5	shift	_	NOUN	_	Number=Sing	_	_	_	_
6	assays	_	NOUN	_	Number=Plur	_	_	_	_
7	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	CMV	_	PROPN	_	Number=Sing	_	_	_	_
10	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	formation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	complexes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CMV	_	PROPN	_	Number=Sing	_	_	_	_
6	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	factors	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	8	_	NUM	_	NumType=Card	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012240	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	independent	_	ADJ	_	Degree=Pos	_	_	_	_
6	cis	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
9	sequences	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	HIV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	LTR	_	PROPN	_	Number=Sing	_	_	_	_
15	responsive	_	ADJ	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	rate	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	initiation	_	NOUN	_	Number=Sing	_	_	_	_
6	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	long	_	ADJ	_	Degree=Pos	_	_	_	_
10	terminal	_	NOUN	_	Number=Sing	_	_	_	_
11	repeat	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	LTR	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	increases	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
24	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	T	_	PROPN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	HIV	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	LTR	_	NOUN	_	Number=Sing	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	governed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	independent	_	ADJ	_	Degree=Pos	_	_	_	_
19	sequences	_	NOUN	_	Number=Plur	_	_	_	_
20	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	5'	_	NUM	_	_	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	initiation	_	NOUN	_	Number=Sing	_	_	_	_
28	sequences	_	NOUN	_	Number=Plur	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	either	_	CCONJ	_	_	_	_	_	_
32	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	kappa	_	PROPN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	rate	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	LTR	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	treatment	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	either	_	CCONJ	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
18	ester	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	tumor	_	NOUN	_	Number=Sing	_	_	_	_
21	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	if	_	SCONJ	_	_	_	_	_	_
25	either	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	binding	_	NOUN	_	Number=Sing	_	_	_	_
35	sites	_	NOUN	_	Number=Plur	_	_	_	_
36	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	deleted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	but	_	CCONJ	_	_	_	_	_	_
40	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	to	_	PART	_	_	_	_	_	_
42	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
45	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
46	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
47	if	_	SCONJ	_	_	_	_	_	_
48	both	_	DET	_	_	_	_	_	_
49	sequences	_	NOUN	_	Number=Plur	_	_	_	_
50	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
51	absent	_	ADJ	_	Degree=Pos	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	HIV	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	mutant	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	kappa	_	PROPN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	deletion	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	able	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	although	_	SCONJ	_	_	_	_	_	_
22	at	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	much	_	ADV	_	_	_	_	_	_
25	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	growth	_	NOUN	_	Number=Sing	_	_	_	_
27	rate	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	while	_	SCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	deletion	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	alone	_	ADV	_	_	_	_	_	_
37	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	viral	_	ADJ	_	Degree=Pos	_	_	_	_
40	growth	_	NOUN	_	Number=Sing	_	_	_	_
41	rate	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Neither	_	DET	_	_	_	_	_	_
2	deletion	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	nor	_	CCONJ	_	_	_	_	_	_
8	deletion	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	viral	_	ADJ	_	Degree=Pos	_	_	_	_
17	replication	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
20	ester	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012241	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Control	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	I	_	PRON	_	Number=Sing	_	_	_	_
11	kappa	_	VERB	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	PROPN	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	maintained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
13	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
14	state	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	kappa	_	VERB	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	kappa	_	VERB	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	alpha	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	kappa	_	VERB	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	purified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	through	_	ADP	_	_	_	_	_	_
30	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	association	_	NOUN	_	Number=Sing	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	p65	_	NOUN	_	Number=Sing	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	c	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	Rel	_	NOUN	_	Number=Sing	_	_	_	_
39	subunits	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	third	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
9	NF	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	VERB	_	Number=Sing	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	large	_	ADJ	_	Degree=Pos	_	_	_	_
6	variety	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	inducers	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	kappa	_	VERB	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	VERB	_	Number=Sing	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	beta	_	NOUN	_	Number=Sing	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	proteolytically	_	ADV	_	_	_	_	_	_
21	degraded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	translocation	_	NOUN	_	Number=Sing	_	_	_	_
30	into	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	E29.1	_	NUM	_	NumType=Card	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	hybridoma	_	NOUN	_	Number=Sing	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	kappa	_	VERB	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	alpha	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	VERB	_	Number=Sing	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	beta	_	NOUN	_	Number=Sing	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	equally	_	ADV	_	_	_	_	_	_
21	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	p65	_	NUM	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
27	kappa	_	VERB	_	Number=Sing	_	_	_	_
28	B	_	PROPN	_	Number=Sing	_	_	_	_
29	beta	_	NOUN	_	Number=Sing	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	degraded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	response	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	TNF	_	PROPN	_	Number=Sing	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	contrast	_	NOUN	_	Number=Sing	_	_	_	_
39	to	_	SCONJ	_	_	_	_	_	_
40	what	_	PRON	_	PronType=Int	_	_	_	_
41	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
43	originally	_	ADV	_	_	_	_	_	_
44	published	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	unlike	_	SCONJ	_	_	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	kappa	_	VERB	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	kappa	_	VERB	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	beta	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	constitutively	_	ADV	_	_	_	_	_	_
19	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	resynthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	as	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	hypophosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
25	form	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	absence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	slow	_	ADJ	_	Degree=Pos	_	_	_	_
5	migrating	_	NOUN	_	VerbForm=Ger	_	_	_	_
6	forms	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	kappa	_	VERB	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	following	_	VERB	_	VerbForm=Ger	_	_	_	_
13	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
14	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
18	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	necessarily	_	ADV	_	_	_	_	_	_
21	constitute	_	VERB	_	VerbForm=Inf	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	signal	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	event	_	NOUN	_	Number=Sing	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	targets	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	molecule	_	NOUN	_	Number=Sing	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012248	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Lipopolysaccharide	_	NOUN	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	tissue	_	NOUN	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	p65	_	NOUN	_	Number=Sing	_	_	_	_
19	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	like	_	ADJ	_	Degree=Pos	_	_	_	_
26	site	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Exposure	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	bacterial	_	VERB	_	Degree=Pos	_	_	_	_
7	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	LPS	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	Rel	_	NOUN	_	Number=Sing	_	_	_	_
19	family	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
27	induction	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	products	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	including	_	VERB	_	VerbForm=Ger	_	_	_	_
34	tissue	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	TF	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	TF	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	primary	_	ADJ	_	Degree=Pos	_	_	_	_
5	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
6	initiator	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	coagulation	_	NOUN	_	Number=Sing	_	_	_	_
10	protease	_	NOUN	_	Number=Sing	_	_	_	_
11	cascades	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	characterization	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	complex	_	NOUN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	bound	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	kappa	_	PROPN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	like	_	ADJ	_	Degree=Pos	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	5'-	_	PROPN	_	_	_	_	_	_
25	CGGAGTTTCC	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	3	_	NUM	_	NumType=Card	_	_	_	_
28	'	_	PUNCT	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	5'-	_	NOUN	_	_	_	_	_	_
33	flanking	_	VERB	_	Number=Sing	_	_	_	_
34	region	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	human	_	ADJ	_	Degree=Pos	_	_	_	_
38	TF	_	NOUN	_	Number=Sing	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	complex	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	LPS	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	preceded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	TF	_	PROPN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	TF	_	PROPN	_	Number=Sing	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	bound	_	VERB	_	Degree=Pos	_	_	_	_
11	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	p65	_	NUM	_	Number=Sing	_	_	_	_
15	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	not	_	ADV	_	_	_	_	_	_
18	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
19	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	p50	_	NUM	_	Number=Sing	_	_	_	_
22	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Base	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	pair	_	NOUN	_	Number=Sing	_	_	_	_
4	substitutions	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	TF	_	PROPN	_	Number=Sing	_	_	_	_
8	site	_	NOUN	_	Number=Sing	_	_	_	_
9	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	presence	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	cytosine	_	NOUN	_	Number=Sing	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	position	_	NOUN	_	Number=Sing	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	precluded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	fact	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	under	_	ADP	_	_	_	_	_	_
5	low	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	ionic	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	strength	_	NOUN	_	Number=Sing	_	_	_	_
10	conditions	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	TF	_	NOUN	_	Number=Sing	_	_	_	_
14	complex	_	NOUN	_	Number=Sing	_	_	_	_
15	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	migrate	_	VERB	_	VerbForm=Inf	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	p50/p65	_	NUM	_	Number=Sing	_	_	_	_
21	dimers	_	NOUN	_	Number=Plur	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	instead	_	ADV	_	_	_	_	_	_
24	comigrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	p65	_	NOUN	_	Number=Sing	_	_	_	_
29	dimers	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Antibodies	_	NOUN	_	Number=Plur	_	_	_	_
2	against	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	Rel	_	PROPN	_	Number=Sing	_	_	_	_
10	proteins	_	PROPN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	UV	_	PROPN	_	Number=Sing	_	_	_	_
13	cross	_	VERB	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
16	studies	_	NOUN	_	Number=Plur	_	_	_	_
17	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	presence	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	c	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	Rel	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	p65	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	absence	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	p50	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	TF	_	PROPN	_	Number=Sing	_	_	_	_
34	complex	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	further	_	ADV	_	_	_	_	_	_
37	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	that	_	SCONJ	_	_	_	_	_	_
39	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
40	/	_	PUNCT	_	_	_	_	_	_
41	p65	_	NOUN	_	Number=Sing	_	_	_	_
42	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
43	selectively	_	ADV	_	_	_	_	_	_
44	bound	_	ADJ	_	Degree=Pos	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	TF	_	PROPN	_	Number=Sing	_	_	_	_
48	kappa	_	PROPN	_	Number=Sing	_	_	_	_
49	B	_	NOUN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	like	_	ADJ	_	Degree=Pos	_	_	_	_
52	site	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	TF	_	PROPN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	conferred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	LPS	_	PROPN	_	Number=Sing	_	_	_	_
10	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	transactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	p65	_	NUM	_	NumType=Card	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	p65	_	NOUN	_	Number=Sing	_	_	_	_
13	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	novel	_	NOUN	_	Number=Sing	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	like	_	ADJ	_	Degree=Pos	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	LPS	_	PROPN	_	Number=Sing	_	_	_	_
24	induction	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	TF	_	PROPN	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012250	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	thiol	_	ADJ	_	Number=Sing	_	_	_	_
3	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
4	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	IgE	_	PROPN	_	Number=Sing	_	_	_	_
6	isotype	_	NOUN	_	Number=Sing	_	_	_	_
7	switching	_	VERB	_	VerbForm=Ger	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	site	_	NOUN	_	Number=Sing	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	present	_	ADJ	_	Degree=Pos	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	promoter	_	ADJ	_	Number=Sing	_	_	_	_
19	region	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	germline	_	NOUN	_	Number=Sing	_	_	_	_
23	Cepsilon	_	PROPN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	but	_	CCONJ	_	_	_	_	_	_
27	there	_	PRON	_	_	_	_	_	_
28	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	little	_	ADJ	_	Degree=Pos	_	_	_	_
30	information	_	NOUN	_	Number=Sing	_	_	_	_
31	on	_	SCONJ	_	_	_	_	_	_
32	whether	_	SCONJ	_	_	_	_	_	_
33	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
34	factor	_	NOUN	_	Number=Sing	_	_	_	_
35	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	involved	_	ADJ	_	Degree=Pos	_	_	_	_
37	in	_	SCONJ	_	_	_	_	_	_
38	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
39	IgE	_	PROPN	_	Number=Sing	_	_	_	_
40	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	human	_	ADJ	_	Degree=Pos	_	_	_	_
43	B	_	NOUN	_	Number=Sing	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Accordingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	germline	_	NOUN	_	Number=Sing	_	_	_	_
13	Cepsilon	_	NOUN	_	Number=Sing	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	SCONJ	_	_	_	_	_	_
16	using	_	VERB	_	VerbForm=Ger	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	Burkitt	_	NOUN	_	Number=Sing	_	_	_	_
20	's	_	PART	_	_	_	_	_	_
21	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	lines	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	DND39	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	DG75	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	both	_	DET	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	n-acetyl	_	PROPN	_	Number=Sing	_	_	_	_
7	-L	_	PUNCT	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	cysteine	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	NAC	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	potent	_	ADJ	_	Number=Sing	_	_	_	_
16	thiol	_	ADJ	_	Number=Sing	_	_	_	_
17	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	triggering	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	4	_	NUM	_	NumType=Card	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	anti-CD40	_	NUM	_	Number=Sing	_	_	_	_
37	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
38	antibody	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	4	_	NUM	_	NumType=Card	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	signal	_	NOUN	_	Number=Sing	_	_	_	_
7	transducers	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	activators	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	STAT	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	addition	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	NAC	_	NOUN	_	Number=Sing	_	_	_	_
24	treatment	_	NOUN	_	Number=Sing	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	transfection	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	decoy	_	NOUN	_	Number=Sing	_	_	_	_
30	oligodeoxynucleotides	_	NOUN	_	Number=Plur	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	STAT6	_	NOUN	_	Number=Sing	_	_	_	_
37	only	_	ADV	_	_	_	_	_	_
38	partly	_	ADV	_	_	_	_	_	_
39	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	4	_	NUM	_	NumType=Card	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	germline	_	NOUN	_	Number=Sing	_	_	_	_
46	Cepsilon	_	NOUN	_	Number=Sing	_	_	_	_
47	transcription	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	decoy	_	NOUN	_	Number=Sing	_	_	_	_
6	oligodeoxynucleotides	_	NOUN	_	Number=Plur	_	_	_	_
7	together	_	ADV	_	_	_	_	_	_
8	almost	_	ADV	_	_	_	_	_	_
9	completely	_	ADV	_	_	_	_	_	_
10	abrogated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	germline	_	NOUN	_	Number=Sing	_	_	_	_
17	Cepsilon	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Of	_	ADP	_	_	_	_	_	_
2	note	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	CD40	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	germline	_	NOUN	_	Number=Sing	_	_	_	_
15	Cepsilon	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	markedly	_	ADV	_	_	_	_	_	_
19	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	NAC	_	PROPN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	decoy	_	NOUN	_	Number=Sing	_	_	_	_
26	oligodeoxynucleotide	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NAC	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	deletional	_	ADJ	_	Degree=Pos	_	_	_	_
10	switch	_	NOUN	_	Number=Sing	_	_	_	_
11	recombination	_	NOUN	_	Number=Sing	_	_	_	_
12	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	isotype	_	NOUN	_	Number=Sing	_	_	_	_
15	switch	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	IgE	_	PROPN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	NAC	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	generation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Smu	_	PROPN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	Sepsilon	_	NOUN	_	Number=Sing	_	_	_	_
9	switch	_	NOUN	_	Number=Sing	_	_	_	_
10	fragments	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	normal	_	ADJ	_	Degree=Pos	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	costimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	4	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	anti-CD40	_	NUM	_	Number=Sing	_	_	_	_
23	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
24	antibody	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	abolished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	CD40	_	PROPN	_	Number=Sing	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	promoted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	CD23	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	coordination	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	STAT6	_	NOUN	_	Number=Sing	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	germline	_	NOUN	_	Number=Sing	_	_	_	_
19	Cepsilon	_	NOUN	_	Number=Sing	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	CD40	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	may	_	AUX	_	VerbForm=Fin	_	_	_	_
36	be	_	AUX	_	VerbForm=Inf	_	_	_	_
37	important	_	ADJ	_	Degree=Pos	_	_	_	_
38	in	_	SCONJ	_	_	_	_	_	_
39	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
40	both	_	CCONJ	_	_	_	_	_	_
41	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	germline	_	NOUN	_	Number=Sing	_	_	_	_
44	Cepsilon	_	NOUN	_	Number=Sing	_	_	_	_
45	transcription	_	NOUN	_	Number=Sing	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	class	_	NOUN	_	Number=Sing	_	_	_	_
48	switching	_	VERB	_	Number=Sing	_	_	_	_
49	to	_	ADP	_	_	_	_	_	_
50	IgE	_	PROPN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012253	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
3	pathways	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	5	_	NUM	_	NumType=Card	_	_	_	_
8	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	allergen	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
15	clones	_	NOUN	_	Number=Plur	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	GC	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	long	_	ADV	_	Degree=Pos	_	_	_	_
7	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
8	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	most	_	ADV	_	_	_	_	_	_
12	effective	_	ADJ	_	Degree=Pos	_	_	_	_
13	agents	_	NOUN	_	Number=Plur	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	treatment	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	allergic	_	ADJ	_	Degree=Pos	_	_	_	_
19	diseases	_	NOUN	_	Number=Plur	_	_	_	_
20	accompanied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	eosinophilia	_	NOUN	_	Number=Sing	_	_	_	_
23	such	_	ADJ	_	Degree=Pos	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
26	asthma	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	atopic	_	ADJ	_	Number=Sing	_	_	_	_
29	dermatitis	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	development	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	chronic	_	ADJ	_	Number=Sing	_	_	_	_
5	eosinophilic	_	ADJ	_	Degree=Pos	_	_	_	_
6	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	5	_	NUM	_	NumType=Card	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	SYM	_	_	_	_	_	_
16	5	_	NUM	_	NumType=Card	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	selective	_	ADJ	_	Degree=Pos	_	_	_	_
21	eosinophil	_	ADJ	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	activating	_	ADJ	_	VerbForm=Ger	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	helper	_	NOUN	_	Number=Sing	_	_	_	_
29	T	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	delineate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	5	_	NUM	_	NumType=Card	_	_	_	_
11	synthesis	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	established	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	allergen	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	CD4	_	NOUN	_	Number=Sing	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	clones	_	NOUN	_	Number=Plur	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	asthmatic	_	ADJ	_	Degree=Pos	_	_	_	_
7	patients	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	GC	_	PROPN	_	Number=Sing	_	_	_	_
2	efficiently	_	ADV	_	_	_	_	_	_
3	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	5	_	NUM	_	NumType=Card	_	_	_	_
7	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
10	clones	_	NOUN	_	Number=Plur	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	via	_	ADP	_	_	_	_	_	_
13	either	_	CCONJ	_	_	_	_	_	_
14	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	TCR	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2R	_	NUM	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	upon	_	ADP	_	_	_	_	_	_
8	TCR	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2R	_	PROPN	_	Number=Sing	_	_	_	_
13	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	totally	_	ADV	_	_	_	_	_	_
16	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	5	_	NUM	_	NumType=Card	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	construct	_	VERB	_	Number=Sing	_	_	_	_
12	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
15	clones	_	NOUN	_	Number=Plur	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	either	_	CCONJ	_	_	_	_	_	_
20	TCR	_	NOUN	_	Number=Sing	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2R	_	NUM	_	Number=Sing	_	_	_	_
25	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	clearly	_	ADV	_	_	_	_	_	_
29	downregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
34	that	_	SCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	approximately	_	ADV	_	_	_	_	_	_
37	500	_	NUM	_	NumType=Card	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	bp	_	NOUN	_	Number=Sing	_	_	_	_
40	human	_	ADJ	_	Degree=Pos	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	5	_	NUM	_	NumType=Card	_	_	_	_
44	gene	_	NOUN	_	Number=Sing	_	_	_	_
45	segment	_	NOUN	_	Number=Sing	_	_	_	_
46	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	5	_	NUM	_	NumType=Card	_	_	_	_
48	'	_	PUNCT	_	_	_	_	_	_
49	upstream	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	coding	_	NOUN	_	Number=Sing	_	_	_	_
53	region	_	NOUN	_	Number=Sing	_	_	_	_
54	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
55	activation	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
58	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
59	elements	_	NOUN	_	Number=Plur	_	_	_	_
60	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
61	for	_	ADP	_	_	_	_	_	_
62	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
63	regulation	_	NOUN	_	Number=Sing	_	_	_	_
64	by	_	ADP	_	_	_	_	_	_
65	GC	_	PROPN	_	Number=Sing	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	PROPN	_	Number=Sing	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	AP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	among	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	possible	_	ADJ	_	Degree=Pos	_	_	_	_
19	targets	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	GC	_	NOUN	_	Number=Sing	_	_	_	_
22	actions	_	NOUN	_	Number=Plur	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	TCR	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	AT	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	significantly	_	ADV	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	showing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	GC	_	PROPN	_	Number=Sing	_	_	_	_
6	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	5	_	NUM	_	NumType=Card	_	_	_	_
10	production	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	CD4	_	NOUN	_	Number=Sing	_	_	_	_
14	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
7	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	TCR	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2R	_	NUM	_	Number=Sing	_	_	_	_
14	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	underscore	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	efficacy	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	GC	_	PROPN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	treatment	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	allergic	_	ADJ	_	Degree=Pos	_	_	_	_
26	diseases	_	NOUN	_	Number=Plur	_	_	_	_
27	via	_	ADP	_	_	_	_	_	_
28	suppression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	5	_	NUM	_	NumType=Card	_	_	_	_
34	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012258	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	IL6	_	PROPN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	CREB	_	PROPN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	ATF	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	SP1	_	NOUN	_	Number=Sing	_	_	_	_
20	proteins	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	U937	_	PROPN	_	Number=Sing	_	_	_	_
23	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	IL6	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	important	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
8	regulator	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	activated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
14	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	IL6	_	PROPN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	only	_	ADJ	_	Degree=Pos	_	_	_	_
25	CCAAT	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	binding	_	VERB	_	Number=Sing	_	_	_	_
30	protein	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	C	_	NOUN	_	Number=Sing	_	_	_	_
33	/	_	PUNCT	_	_	_	_	_	_
34	EBP	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	family	_	NOUN	_	Number=Sing	_	_	_	_
37	member	_	NOUN	_	Number=Sing	_	_	_	_
38	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
39	steady	_	ADJ	_	Degree=Pos	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	state	_	NOUN	_	Number=Sing	_	_	_	_
42	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
43	levels	_	NOUN	_	Number=Plur	_	_	_	_
44	increase	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
45	upon	_	ADP	_	_	_	_	_	_
46	activation	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	1	_	NUM	_	NumType=Card	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	IL6	_	PROPN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	at	_	ADV	_	_	_	_	_	_
16	least	_	ADV	_	Degree=Sup	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	part	_	NOUN	_	Degree=Pos	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	induction	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	IL6	_	PROPN	_	Number=Sing	_	_	_	_
26	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
27	following	_	VERB	_	VerbForm=Ger	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	U937	_	NUM	_	Number=Sing	_	_	_	_
31	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	104	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	bp	_	NOUN	_	Number=Sing	_	_	_	_
8	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	region	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	IL6	_	PROPN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	basal	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	induction	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	U937	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
5	sites	_	NOUN	_	Number=Plur	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
9	response	_	NOUN	_	Number=Sing	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	CREB	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	ATF	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
25	families	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Each	_	DET	_	_	_	_	_	_
2	site	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	functionally	_	ADV	_	_	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	independently	_	ADV	_	_	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	IL6	_	PROPN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	U937	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012260	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
4	sequences	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	MCF13	_	PROPN	_	Number=Sing	_	_	_	_
11	murine	_	NOUN	_	Number=Sing	_	_	_	_
12	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	long	_	ADJ	_	Degree=Pos	_	_	_	_
15	terminal	_	NOUN	_	Number=Sing	_	_	_	_
16	repeat	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	downstream	_	ADV	_	Degree=Pos	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	DEN	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	long	_	ADJ	_	Degree=Pos	_	_	_	_
13	terminal	_	NOUN	_	Number=Sing	_	_	_	_
14	repeat	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	mink	_	NOUN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	focus	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
22	murine	_	NOUN	_	Number=Sing	_	_	_	_
23	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
24	virus	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	important	_	ADJ	_	Degree=Pos	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	viral	_	ADJ	_	Degree=Pos	_	_	_	_
29	pathogenicity	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Another	_	DET	_	_	_	_	_	_
2	important	_	ADJ	_	Degree=Pos	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	DEN	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
8	control	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
18	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	critical	_	ADJ	_	Degree=Pos	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012261	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
2	specific	_	ADJ	_	Degree=Pos	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	adenovirus	_	NOUN	_	Degree=Pos	_	_	_	_
8	early	_	ADJ	_	Degree=Pos	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	binding	_	VERB	_	Number=Sing	_	_	_	_
20	motifs	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	primary	_	ADJ	_	Degree=Pos	_	_	_	_
3	site	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	infection	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	adenoviruses	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	viral	_	ADJ	_	Degree=Pos	_	_	_	_
7	control	_	NOUN	_	Number=Sing	_	_	_	_
8	elements	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	adenoviral	_	ADJ	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Sing	_	_	_	_
20	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
23	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	adenovirus	_	NOUN	_	Number=Sing	_	_	_	_
3	early	_	ADJ	_	Degree=Pos	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	ES	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	products	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	involved	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	maintenance	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	viral	_	ADJ	_	Degree=Pos	_	_	_	_
18	persistence	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	SCONJ	_	_	_	_	_	_
20	complexing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	class	_	NOUN	_	Number=Sing	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	MHC	_	AUX	_	Number=Sing	_	_	_	_
26	antigens	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	thus	_	ADV	_	_	_	_	_	_
29	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
30	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	surface	_	NOUN	_	Number=Sing	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	resultant	_	ADJ	_	Degree=Pos	_	_	_	_
37	decrease	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	host	_	ADJ	_	Number=Sing	_	_	_	_
40	immunologic	_	ADJ	_	Degree=Pos	_	_	_	_
41	destruction	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	different	_	ADJ	_	Degree=Pos	_	_	_	_
5	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	involved	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	E3	_	PROPN	_	Number=Sing	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	as	_	SCONJ	_	_	_	_	_	_
15	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	transfection	_	NOUN	_	Number=Sing	_	_	_	_
25	analysis	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	E3	_	NOUN	_	Number=Sing	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	both	_	DET	_	_	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	types	_	NOUN	_	Number=Plur	_	_	_	_
34	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	detected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	novel	_	NOUN	_	Number=Sing	_	_	_	_
6	domains	_	NOUN	_	Number=Plur	_	_	_	_
7	referred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	L1	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	L2	_	PROPN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	variety	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
18	but	_	CCONJ	_	_	_	_	_	_
19	not	_	ADV	_	_	_	_	_	_
20	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
21	extracts	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Each	_	DET	_	_	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	domains	_	NOUN	_	Number=Plur	_	_	_	_
5	possessed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	strong	_	ADJ	_	Degree=Pos	_	_	_	_
7	homology	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	motifs	_	NOUN	_	Number=Plur	_	_	_	_
10	previously	_	ADV	_	_	_	_	_	_
11	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B.	_	PROPN	_	Number=Sing	_	_	_	_
21	Transfections	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	E3	_	NOUN	_	Number=Sing	_	_	_	_
24	constructs	_	NOUN	_	Number=Plur	_	_	_	_
25	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	chloramphenicol	_	PROPN	_	Number=Sing	_	_	_	_
29	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
30	gene	_	NOUN	_	Number=Sing	_	_	_	_
31	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	that	_	SCONJ	_	_	_	_	_	_
33	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	distal	_	ADJ	_	Number=Sing	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kappa	_	NOUN	_	Number=Sing	_	_	_	_
40	B	_	NOUN	_	Number=Sing	_	_	_	_
41	motif	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	L2	_	X	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
46	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
47	effects	_	NOUN	_	Number=Plur	_	_	_	_
48	on	_	ADP	_	_	_	_	_	_
49	promoter	_	NOUN	_	Number=Sing	_	_	_	_
50	expression	_	NOUN	_	Number=Sing	_	_	_	_
51	in	_	ADP	_	_	_	_	_	_
52	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
53	cells	_	NOUN	_	Number=Plur	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	but	_	CCONJ	_	_	_	_	_	_
56	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
57	in	_	ADP	_	_	_	_	_	_
58	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
59	decreases	_	NOUN	_	Number=Plur	_	_	_	_
60	in	_	ADP	_	_	_	_	_	_
61	expression	_	NOUN	_	Number=Sing	_	_	_	_
62	by	_	ADP	_	_	_	_	_	_
63	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
64	cells	_	NOUN	_	Number=Plur	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
7	NF	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	motif	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	L1	_	X	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
17	effects	_	NOUN	_	Number=Plur	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	but	_	CCONJ	_	_	_	_	_	_
29	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	small	_	ADJ	_	Degree=Pos	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	reproducible	_	ADJ	_	Degree=Pos	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	increase	_	VERB	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	expression	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	when	_	ADV	_	PronType=Int	_	_	_	_
45	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	to	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	L2	_	NOUN	_	Number=Sing	_	_	_	_
49	mutation	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Reversing	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	position	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
6	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	L1	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	L2	_	PROPN	_	Number=Sing	_	_	_	_
12	domains	_	NOUN	_	Number=Plur	_	_	_	_
13	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	primary	_	ADJ	_	Degree=Pos	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
20	motifs	_	NOUN	_	Number=Plur	_	_	_	_
21	rather	_	ADV	_	_	_	_	_	_
22	than	_	ADP	_	_	_	_	_	_
23	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	position	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	E3	_	NOUN	_	Number=Sing	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	critical	_	ADJ	_	Degree=Pos	_	_	_	_
31	for	_	SCONJ	_	_	_	_	_	_
32	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	0030012262	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Megakaryocyte	_	NOUN	_	Number=Sing	_	_	_	_
3	/	_	PUNCT	_	_	_	_	_	_
4	Platelet	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	alpha2beta1	_	PROPN	_	Number=Sing	_	_	_	_
11	integrin	_	NOUN	_	Degree=Pos	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	two	_	NUM	_	NumType=Card	_	_	_	_
15	tandem	_	NOUN	_	Number=Sing	_	_	_	_
16	AP1	_	NOUN	_	Number=Sing	_	_	_	_
17	sites	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	mitogen	_	ADJ	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	kinase	_	NOUN	_	Number=Sing	_	_	_	_
25	signaling	_	VERB	_	Number=Sing	_	_	_	_
26	cascade	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	alpha2beta1	_	PROPN	_	Number=Sing	_	_	_	_
3	integrin	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	collagen	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	platelets	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	megakaryocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	normal	_	ADJ	_	Degree=Pos	_	_	_	_
17	platelet	_	NOUN	_	Number=Sing	_	_	_	_
18	function	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	alpha2	_	NOUN	_	Number=Sing	_	_	_	_
6	integrin	_	VERB	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	undergoing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	core	_	NOUN	_	Number=Sing	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	between	_	ADP	_	_	_	_	_	_
18	bp	_	PROPN	_	Number=Sing	_	_	_	_
19	-30	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	-	_	SYM	_	_	_	_	_	_
22	92	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	silencer	_	NOUN	_	Number=Sing	_	_	_	_
26	between	_	ADP	_	_	_	_	_	_
27	bp	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	92	_	NUM	_	NumType=Card	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	-	_	SYM	_	_	_	_	_	_
32	351	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
36	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	distal	_	NOUN	_	Degree=Pos	_	_	_	_
40	5	_	NUM	_	NumType=Card	_	_	_	_
41	'	_	PUNCT	_	_	_	_	_	_
42	flank	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	now	_	ADV	_	_	_	_	_	_
4	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	229	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	bp	_	PROPN	_	Number=Sing	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	distal	_	ADJ	_	Degree=Pos	_	_	_	_
13	5	_	NUM	_	NumType=Card	_	_	_	_
14	'	_	PUNCT	_	_	_	_	_	_
15	flank	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	alpha2	_	NOUN	_	Number=Sing	_	_	_	_
19	integrin	_	NOUN	_	Number=Sing	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	high	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	level	_	NOUN	_	Number=Sing	_	_	_	_
26	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
32	features	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	tandem	_	NOUN	_	Number=Sing	_	_	_	_
3	AP1	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
5	sites	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	dyad	_	ADJ	_	Degree=Pos	_	_	_	_
8	symmetry	_	NOUN	_	Number=Sing	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	DNA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	complex	_	ADJ	_	Number=Sing	_	_	_	_
20	formation	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	members	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	c-fos	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	c	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	jun	_	NOUN	_	Number=Sing	_	_	_	_
30	family	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	requirement	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	AP1	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
20	pathway	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	SCONJ	_	_	_	_	_	_
22	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	alpha2	_	NOUN	_	Number=Sing	_	_	_	_
24	integrin	_	PROPN	_	Degree=Pos	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	MAP	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	cascade	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	PD98059	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	MAPK	_	PROPN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	alpha2	_	NOUN	_	Number=Sing	_	_	_	_
24	integrin	_	NOUN	_	Number=Sing	_	_	_	_
25	subunit	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	become	_	VERB	_	VerbForm=Inf	_	_	_	_
31	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	model	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
7	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	which	_	DET	_	PronType=Rel	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	alpha2	_	NOUN	_	Number=Sing	_	_	_	_
14	integrin	_	VERB	_	Degree=Pos	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
18	via	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	MAP	_	NOUN	_	Number=Sing	_	_	_	_
21	kinase	_	NOUN	_	Number=Sing	_	_	_	_
22	pathway	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
25	two	_	NUM	_	NumType=Card	_	_	_	_
26	tandem	_	NOUN	_	Number=Sing	_	_	_	_
27	AP1	_	NOUN	_	Number=Sing	_	_	_	_
28	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
29	sites	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	alpha2	_	NOUN	_	Number=Sing	_	_	_	_
33	integrin	_	NOUN	_	Number=Sing	_	_	_	_
34	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012269	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
2	NF	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	granulopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
13	lethality	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	VERB	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
21	mice	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	belonging	_	VERB	_	VerbForm=Ger	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	family	_	NOUN	_	Number=Sing	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	VERB	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	mainly	_	ADV	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	kappa	_	VERB	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	alpha	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
27	kappa	_	VERB	_	Number=Sing	_	_	_	_
28	B	_	PROPN	_	Number=Sing	_	_	_	_
29	beta	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Apparently	_	ADV	_	_	_	_	_	_
2	normal	_	ADJ	_	Degree=Pos	_	_	_	_
3	at	_	ADP	_	_	_	_	_	_
4	birth	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	kappa	_	VERB	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	-/-	_	PUNCT	_	_	_	_	_	_
11	mice	_	NOUN	_	Number=Plur	_	_	_	_
12	exhibit	_	VERB	_	Number=Sing	_	_	_	_
13	severe	_	ADJ	_	Degree=Pos	_	_	_	_
14	runting	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	skin	_	NOUN	_	Number=Sing	_	_	_	_
17	defects	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	extensive	_	ADJ	_	Degree=Pos	_	_	_	_
21	granulopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
22	postnatally	_	ADV	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	typically	_	ADV	_	_	_	_	_	_
25	dying	_	VERB	_	VerbForm=Ger	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	8	_	NUM	_	NumType=Card	_	_	_	_
28	days	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
2	tissues	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	mice	_	NOUN	_	Number=Plur	_	_	_	_
6	display	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	NF	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	some	_	DET	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	not	_	ADV	_	_	_	_	_	_
23	all	_	DET	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	genes	_	NOUN	_	Number=Plur	_	_	_	_
26	thought	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	be	_	AUX	_	VerbForm=Inf	_	_	_	_
29	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	PROPN	_	Number=Sing	_	_	_	_
34	B.	_	PROPN	_	Number=Sing	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	elevation	_	NOUN	_	Number=Sing	_	_	_	_
40	results	_	NOUN	_	Number=Plur	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
43	phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
44	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
45	because	_	SCONJ	_	_	_	_	_	_
46	mice	_	NOUN	_	Number=Plur	_	_	_	_
47	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
48	both	_	CCONJ	_	_	_	_	_	_
49	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
50	kappa	_	VERB	_	Number=Sing	_	_	_	_
51	B	_	PROPN	_	Number=Sing	_	_	_	_
52	alpha	_	NOUN	_	Number=Sing	_	_	_	_
53	and	_	CCONJ	_	_	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	p50	_	PROPN	_	Number=Sing	_	_	_	_
56	subunit	_	NOUN	_	Number=Sing	_	_	_	_
57	of	_	ADP	_	_	_	_	_	_
58	NF	_	PROPN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	kappa	_	NOUN	_	Number=Sing	_	_	_	_
61	B	_	PROPN	_	Number=Sing	_	_	_	_
62	show	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
63	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
64	dramatically	_	ADV	_	_	_	_	_	_
65	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
66	onset	_	NOUN	_	Number=Sing	_	_	_	_
67	of	_	ADP	_	_	_	_	_	_
68	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
69	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	kappa	_	VERB	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	-/-	_	PUNCT	_	_	_	_	_	_
12	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
13	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
14	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
16	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
17	NF	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	as	_	ADV	_	_	_	_	_	_
23	well	_	ADV	_	Degree=Pos	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	normal	_	ADJ	_	Degree=Pos	_	_	_	_
26	signal	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	that	_	PRON	_	PronType=Rel	_	_	_	_
35	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
39	kappa	_	VERB	_	Number=Sing	_	_	_	_
40	B	_	PROPN	_	Number=Sing	_	_	_	_
41	beta	_	NOUN	_	Number=Sing	_	_	_	_
42	degradation	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	kappa	_	VERB	_	Number=Sing	_	_	_	_
7	b	_	NOUN	_	Number=Sing	_	_	_	_
8	beta	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	not	_	ADV	_	_	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	kappa	_	VERB	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	signal	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	kappa	_	VERB	_	Number=Sing	_	_	_	_
5	B	_	PROPN	_	Number=Sing	_	_	_	_
6	alpha	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	postinduction	_	NOUN	_	Number=Sing	_	_	_	_
12	repression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	define	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
5	roles	_	NOUN	_	Number=Plur	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	forms	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	kappa	_	VERB	_	Number=Sing	_	_	_	_
13	B	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	necessity	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	stringent	_	ADJ	_	Degree=Pos	_	_	_	_
20	control	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	PROPN	_	Number=Sing	_	_	_	_
25	B.	_	PROPN	_	Number=Sing	_	_	_	_
26	Document	_	NOUN	_	Number=Sing	_	_	_	_
27	0030012274	_	NUM	_	NumType=Card	_	_	_	_
28	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	evolutionarily	_	ADV	_	_	_	_	_	_
3	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	sequence	_	NOUN	_	Number=Sing	_	_	_	_
5	upstream	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	Ig	_	PROPN	_	Number=Sing	_	_	_	_
10	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
11	chain	_	NOUN	_	Number=Sing	_	_	_	_
12	S	_	PART	_	_	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	3	_	NUM	_	NumType=Card	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	:	_	PUNCT	_	_	_	_	_	_
21	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	CD40	_	PROPN	_	Number=Sing	_	_	_	_
25	ligand	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	4	_	NUM	_	NumType=Card	_	_	_	_
30	via	_	ADP	_	_	_	_	_	_
31	cooperative	_	ADJ	_	Number=Sing	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappa	_	NOUN	_	Number=Sing	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	STAT	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	6	_	NUM	_	NumType=Card	_	_	_	_
40	binding	_	NOUN	_	Number=Sing	_	_	_	_
41	sites	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Germline	_	NOUN	_	Number=Sing	_	_	_	_
2	C	_	PROPN	_	Number=Sing	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
9	event	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	process	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	switch	_	VERB	_	VerbForm=Inf	_	_	_	_
17	DNA	_	NOUN	_	Number=Sing	_	_	_	_
18	recombination	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	IgG	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	regulation	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	human	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	poorly	_	ADV	_	_	_	_	_	_
30	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	took	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	advantage	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
6	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
7	model	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	germinal	_	ADJ	_	Degree=Pos	_	_	_	_
10	center	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	IgM	_	PROPN	_	Number=Sing	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_

1	IgD	_	PROPN	_	Number=Sing	_	_	_	_
2	+	_	SYM	_	_	_	_	_	_
3	CL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	01	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	define	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	gamma	_	NOUN	_	Number=Sing	_	_	_	_
16	3	_	NUM	_	NumType=Card	_	_	_	_
17	evolutionarily	_	ADV	_	_	_	_	_	_
18	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	sequence	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	ECS	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	germline	_	NOUN	_	Number=Sing	_	_	_	_
26	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	C	_	NOUN	_	Number=Sing	_	_	_	_
32	gamma	_	NOUN	_	Number=Sing	_	_	_	_
33	3	_	NUM	_	NumType=Card	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	3	_	NUM	_	NumType=Card	_	_	_	_
5	ECS	_	PROPN	_	Number=Sing	_	_	_	_
6	lies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	upstream	_	NOUN	_	_	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	major	_	ADJ	_	Degree=Pos	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	gamma	_	VERB	_	Number=Sing	_	_	_	_
13	3	_	NUM	_	NumType=Card	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	initiation	_	NOUN	_	Number=Sing	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	displays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	more	_	ADJ	_	Degree=Cmp	_	_	_	_
20	than	_	ADP	_	_	_	_	_	_
21	90	_	NUM	_	NumType=Card	_	_	_	_
22	%	_	SYM	_	Number=Sing	_	_	_	_
23	identity	_	NOUN	_	Number=Sing	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
29	gamma	_	NOUN	_	Number=Sing	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
33	gamma	_	PROPN	_	Number=Sing	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
38	gamma	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	4	_	NUM	_	NumType=Card	_	_	_	_
40	regions	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Reporter	_	NOUN	_	Number=Sing	_	_	_	_
2	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	vectors	_	NOUN	_	Number=Plur	_	_	_	_
5	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	ECS	_	PROPN	_	Number=Sing	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	transfect	_	VERB	_	VerbForm=Inf	_	_	_	_
15	CL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	01	_	NUM	_	NumType=Card	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
23	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	undergo	_	VERB	_	VerbForm=Inf	_	_	_	_
26	Smu	_	PROPN	_	Number=Sing	_	_	_	_
27	-->S	_	NOUN	_	_	_	_	_	_
28	gamma	_	NOUN	_	Number=Sing	_	_	_	_
29	3	_	NUM	_	NumType=Card	_	_	_	_
30	DNA	_	NOUN	_	Number=Sing	_	_	_	_
31	recombination	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	upon	_	ADP	_	_	_	_	_	_
34	engagement	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	CD40	_	NOUN	_	Number=Sing	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	CD40	_	PROPN	_	Number=Sing	_	_	_	_
39	ligand	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	CD40L	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	exposure	_	NOUN	_	Number=Sing	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	IL	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	4	_	NUM	_	NumType=Card	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	CL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	01	_	NUM	_	NumType=Card	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	CD40:CD40L	_	NOUN	_	Number=Sing	_	_	_	_
10	engagement	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	exposure	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	synergistically	_	ADV	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	gamma	_	NOUN	_	Number=Sing	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	ECS	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
24	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
25	reporter	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	mutational	_	ADJ	_	Degree=Pos	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	tandem	_	NOUN	_	Number=Sing	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	Rel	_	NOUN	_	Number=Sing	_	_	_	_
14	binding	_	VERB	_	Number=Sing	_	_	_	_
15	motif	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	critical	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	gamma	_	NOUN	_	Number=Sing	_	_	_	_
21	3	_	NUM	_	NumType=Card	_	_	_	_
22	ECS	_	PROPN	_	Number=Sing	_	_	_	_
23	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	both	_	CCONJ	_	_	_	_	_	_
26	CD40L	_	PROPN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	4	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	while	_	SCONJ	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	STAT	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	6	_	NUM	_	NumType=Card	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	binding	_	NOUN	_	Number=Sing	_	_	_	_
39	site	_	NOUN	_	Number=Sing	_	_	_	_
40	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	additionally	_	ADV	_	_	_	_	_	_
42	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	for	_	ADP	_	_	_	_	_	_
44	IL	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	4	_	NUM	_	NumType=Card	_	_	_	_
47	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	p50/p65	_	NOUN	_	NumType=Card	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	STAT	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	effectively	_	ADV	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	CD40L	_	PROPN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	4	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	respectively	_	ADV	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	specific	_	ADJ	_	Degree=Pos	_	_	_	_
30	DNA	_	NOUN	_	Number=Sing	_	_	_	_
31	motifs	_	NOUN	_	Number=Plur	_	_	_	_
32	within	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	ECS	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	partially	_	ADV	_	_	_	_	_	_
3	overlapping	_	VERB	_	VerbForm=Ger	_	_	_	_
4	CD40L	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
10	elements	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	functionally	_	ADV	_	_	_	_	_	_
13	cooperative	_	ADJ	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	disruption	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	one	_	NUM	_	NumType=Card	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
21	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	gamma	_	NOUN	_	Number=Sing	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	ECS	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	cis	_	NOUN	_	Number=Sing	_	_	_	_
13	elements	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	critically	_	ADV	_	_	_	_	_	_
16	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	CD40L	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	C	_	NOUN	_	Number=Sing	_	_	_	_
30	gamma	_	NOUN	_	Number=Sing	_	_	_	_
31	3	_	NUM	_	NumType=Card	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012283	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	control	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	5	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	helper	_	NOUN	_	Number=Sing	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	:	_	PUNCT	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	5	_	NUM	_	NumType=Card	_	_	_	_
18	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	independently	_	ADV	_	_	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	4	_	NUM	_	NumType=Card	_	_	_	_
30	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	fundamentally	_	ADV	_	_	_	_	_	_
8	involved	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	eosinophilic	_	ADJ	_	Degree=Pos	_	_	_	_
11	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Control	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	production	_	NOUN	_	Number=Sing	_	_	_	_
7	may	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	effective	_	ADJ	_	Degree=Pos	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	management	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	allergic	_	ADJ	_	Degree=Pos	_	_	_	_
15	diseases	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	OBJECTIVE	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	aimed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	find	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	5	_	NUM	_	NumType=Card	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	selectively	_	ADV	_	_	_	_	_	_
17	control	_	VERB	_	VerbForm=Inf	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	5	_	NUM	_	NumType=Card	_	_	_	_
21	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Allergen	_	ADJ	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_

1	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
2	clones	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
5	hybridomas	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	established	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
11	blood	_	NOUN	_	Number=Sing	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	patients	_	NOUN	_	Number=Plur	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	asthma	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	regulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	5	_	NUM	_	NumType=Card	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	transient	_	ADJ	_	Degree=Pos	_	_	_	_
32	transfection	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
35	mobility	_	NOUN	_	Number=Sing	_	_	_	_
36	shift	_	NOUN	_	Number=Sing	_	_	_	_
37	analysis	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	construct	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	pIL	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	SYM	_	_	_	_	_	_
16	5	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	-	_	SYM	_	_	_	_	_	_
19	511	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	Luc	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	5	_	NUM	_	NumType=Card	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
33	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
34	clones	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	but	_	CCONJ	_	_	_	_	_	_
37	not	_	ADV	_	_	_	_	_	_
38	IL	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	5	_	NUM	_	NumType=Card	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	nonproducing	_	NOUN	_	Number=Sing	_	_	_	_
43	clones	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	pIL	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	5(-	_	SYM	_	_	_	_	_	_
4	511	_	NUM	_	NumType=Card	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	Luc	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
11	hybridomas	_	NOUN	_	Number=Plur	_	_	_	_
12	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	fusion	_	NOUN	_	Number=Sing	_	_	_	_
15	between	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	5	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
22	clones	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	5	_	NUM	_	NumType=Card	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	nonexpressing	_	ADJ	_	Degree=Pos	_	_	_	_
31	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
32	line	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	not	_	ADV	_	_	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	hybridomas	_	NOUN	_	Number=Plur	_	_	_	_
38	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	from	_	ADP	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	5	_	NUM	_	NumType=Card	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	nonproducing	_	NUM	_	Number=Sing	_	_	_	_
45	T-	_	PUNCT	_	_	_	_	_	_
46	cell	_	NOUN	_	Number=Sing	_	_	_	_
47	clones	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	5	_	NUM	_	NumType=Card	_	_	_	_
4	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	only	_	ADV	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	AT	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	AP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	TcR	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	although	_	SCONJ	_	_	_	_	_	_
26	there	_	PRON	_	_	_	_	_	_
27	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	no	_	DET	_	_	_	_	_	_
29	significant	_	ADJ	_	Degree=Pos	_	_	_	_
30	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	binding	_	VERB	_	Number=Sing	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSION	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	helper	_	NOUN	_	Number=Sing	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	level	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	unique	_	ADJ	_	Degree=Pos	_	_	_	_
3	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	distinct	_	VERB	_	Number=Sing	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
8	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	control	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	5	_	NUM	_	NumType=Card	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Selective	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	5	_	NUM	_	NumType=Card	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	may	_	AUX	_	VerbForm=Fin	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	useful	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	SCONJ	_	_	_	_	_	_
13	treating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	eosinophlic	_	ADJ	_	Degree=Pos	_	_	_	_
15	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012284	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Monochloramine	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibits	_	VERB	_	Number=Plur	_	_	_	_
3	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
4	ester	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
7	neutrophil	_	NOUN	_	Degree=Pos	_	_	_	_
8	respiratory	_	NOUN	_	Number=Sing	_	_	_	_
9	burst	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	SCONJ	_	_	_	_	_	_
20	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	kinase	_	NOUN	_	Number=Sing	_	_	_	_
24	C	_	NOUN	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Monochloramine	_	NOUN	_	Number=Sing	_	_	_	_
2	derivatives	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	long	_	ADV	_	Degree=Pos	_	_	_	_
5	lived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
7	oxidants	_	NOUN	_	Number=Plur	_	_	_	_
8	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	respiratory	_	NOUN	_	Number=Sing	_	_	_	_
14	burst	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	chemically	_	ADV	_	_	_	_	_	_
5	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	monochloramine	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	NH2Cl	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	C	_	PROPN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	PKC	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	PKC	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	responses	_	NOUN	_	Number=Plur	_	_	_	_
23	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	elicited	_	ADJ	_	Degree=Pos	_	_	_	_
27	rat	_	NOUN	_	Number=Sing	_	_	_	_
28	peritoneal	_	ADJ	_	Degree=Pos	_	_	_	_
29	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	Jurkat	_	ADJ	_	Number=Sing	_	_	_	_
33	T	_	NOUN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
2	pretreated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	NH2Cl	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	30	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	50	_	NUM	_	NumType=Card	_	_	_	_
9	microM	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	decrease	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	respiratory	_	ADJ	_	Number=Sing	_	_	_	_
18	burst	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
23	12	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	myristate	_	NOUN	_	Number=Sing	_	_	_	_
26	13	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	acetate	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	PMA	_	PROPN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	which	_	PRON	_	PronType=Rel	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	potent	_	ADJ	_	Degree=Pos	_	_	_	_
37	PKC	_	NOUN	_	Number=Sing	_	_	_	_
38	activator	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	however	_	ADV	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	viable	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	complete	_	ADJ	_	Degree=Pos	_	_	_	_
12	respiratory	_	ADJ	_	Number=Sing	_	_	_	_
13	burst	_	NOUN	_	Number=Sing	_	_	_	_
14	upon	_	ADP	_	_	_	_	_	_
15	arachidonic	_	ADJ	_	Number=Sing	_	_	_	_
16	acid	_	NOUN	_	Number=Sing	_	_	_	_
17	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	respiratory	_	NOUN	_	Number=Sing	_	_	_	_
23	burst	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	PKC	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	independent	_	ADJ	_	Degree=Pos	_	_	_	_
29	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NH2Cl	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
6	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	decrease	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	PKC	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	PMA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	47	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kDa	_	NOUN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	corresponds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	NADPH	_	PROPN	_	Number=Sing	_	_	_	_
33	oxidase	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	p47	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	phox	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	pretreated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	NH2Cl	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	20	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	SYM	_	_	_	_	_	_
10	70	_	NUM	_	NumType=Card	_	_	_	_
11	microM	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	decrease	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	chain	_	NOUN	_	Number=Sing	_	_	_	_
27	following	_	VERB	_	VerbForm=Ger	_	_	_	_
28	PMA	_	PROPN	_	Number=Sing	_	_	_	_
29	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	decrease	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	PKC	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	also	_	ADV	_	_	_	_	_	_
21	without	_	ADP	_	_	_	_	_	_
22	loss	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	viability	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	NH2Cl	_	PROPN	_	Number=Sing	_	_	_	_
6	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	PKC	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	responses	_	NOUN	_	Number=Plur	_	_	_	_
12	through	_	ADP	_	_	_	_	_	_
13	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
17	PKC	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012289	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
10	blood	_	NOUN	_	Number=Sing	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	According	_	VERB	_	VerbForm=Ger	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	current	_	ADJ	_	Degree=Pos	_	_	_	_
4	models	_	NOUN	_	Number=Plur	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
7	capacity	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	I	_	PRON	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	would	_	AUX	_	VerbForm=Fin	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	retention	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	Rel	_	NOUN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
29	proteins	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	lines	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	when	_	ADV	_	PronType=Int	_	_	_	_
23	overexpressed	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	transient	_	ADJ	_	Degree=Pos	_	_	_	_
26	transfection	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	gain	_	VERB	_	VerbForm=Inf	_	_	_	_
3	better	_	ADJ	_	Degree=Cmp	_	_	_	_
4	insight	_	NOUN	_	Number=Sing	_	_	_	_
5	into	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	potential	_	ADJ	_	Degree=Pos	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	I	_	PRON	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
22	context	_	NOUN	_	Number=Sing	_	_	_	_
23	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
24	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	analysed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	presence	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	human	_	ADJ	_	Degree=Pos	_	_	_	_
33	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
34	blood	_	NOUN	_	Number=Sing	_	_	_	_
35	T	_	NOUN	_	Number=Sing	_	_	_	_
36	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	PBL	_	PROPN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	localization	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	PBL	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	different	_	ADJ	_	Degree=Pos	_	_	_	_
19	techniques	_	NOUN	_	Number=Plur	_	_	_	_
20	:	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	indirect	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	electron	_	ADJ	_	Degree=Pos	_	_	_	_
8	microscopy	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Low	_	ADJ	_	Degree=Pos	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	I	_	PRON	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	whereas	_	SCONJ	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	superinduction	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	after	_	ADP	_	_	_	_	_	_
24	PMA	_	NOUN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	pool	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	I	_	PRON	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
16	stability	_	NOUN	_	Number=Sing	_	_	_	_
17	than	_	ADP	_	_	_	_	_	_
18	cytosolic	_	PROPN	_	Number=Sing	_	_	_	_
19	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	partially	_	ADV	_	_	_	_	_	_
30	independent	_	ADJ	_	Degree=Pos	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	resynthesis	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	protein	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Unexpectedly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	presence	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	I	_	PRON	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	DNA	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	due	_	ADP	_	_	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	presence	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	IkappaBbeta	_	PROPN	_	Number=Sing	_	_	_	_
35	at	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
38	level	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Immunoprecipitation	_	NOUN	_	Number=Sing	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	demonstrate	_	VERB	_	VerbForm=Inf	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	association	_	NOUN	_	Number=Sing	_	_	_	_
8	between	_	ADP	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	I	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	in	_	SCONJ	_	_	_	_	_	_
6	resting	_	VERB	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	PMA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	PBL	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	B	_	PROPN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	present	_	ADJ	_	Degree=Pos	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	apparently	_	ADV	_	_	_	_	_	_
30	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
31	form	_	NOUN	_	Number=Sing	_	_	_	_
32	unable	_	ADJ	_	Degree=Pos	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	disrupt	_	VERB	_	VerbForm=Inf	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
38	binding	_	NOUN	_	Number=Sing	_	_	_	_
39	from	_	ADP	_	_	_	_	_	_
40	DNA	_	PROPN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012290	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tolerance	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
4	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	predominance	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	p50	_	NOUN	_	NumType=Card	_	_	_	_
15	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	line	_	NOUN	_	Number=Sing	_	_	_	_
8	Mono	_	PROPN	_	Number=Sing	_	_	_	_
9	Mac	_	PROPN	_	Number=Sing	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	LPS	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	transient	_	ADJ	_	Degree=Pos	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
24	like	_	ADP	_	_	_	_	_	_
25	tumor	_	NOUN	_	Number=Sing	_	_	_	_
26	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	TNF	_	PROPN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	such	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	precultured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	days	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	low	_	ADJ	_	Degree=Pos	_	_	_	_
12	dose	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	LPS	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	20	_	NUM	_	NumType=Card	_	_	_	_
17	ng	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	ml	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	high	_	ADJ	_	Degree=Pos	_	_	_	_
27	dose	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	LPS	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	microgram	_	NOUN	_	Number=Sing	_	_	_	_
33	/	_	PUNCT	_	_	_	_	_	_
34	ml	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	expression	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	TNF	_	PROPN	_	Number=Sing	_	_	_	_
41	gene	_	NOUN	_	Number=Sing	_	_	_	_
42	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
43	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	i.e.	_	X	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
49	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	run	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	analysis	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	such	_	ADJ	_	Degree=Pos	_	_	_	_
9	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	only	_	ADV	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	low	_	ADJ	_	Degree=Pos	_	_	_	_
15	degree	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
22	operates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	at	_	ADP	_	_	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	upstream	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	level	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CD14	_	PROPN	_	Number=Sing	_	_	_	_
3	LPS	_	PROPN	_	Number=Sing	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	however	_	ADV	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	up	_	ADP	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	down	_	ADV	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	LPS	_	NOUN	_	Number=Plur	_	_	_	_
24	can	_	AUX	_	VerbForm=Fin	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	fact	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	still	_	ADV	_	_	_	_	_	_
30	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	as	_	SCONJ	_	_	_	_	_	_
37	evidenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	transcription	_	NOUN	_	Number=Sing	_	_	_	_
43	factor	_	NOUN	_	Number=Sing	_	_	_	_
44	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
45	factor	_	NOUN	_	Number=Sing	_	_	_	_
46	kappa	_	NOUN	_	Number=Sing	_	_	_	_
47	B	_	PROPN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	NF	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	kappa	_	NOUN	_	Number=Sing	_	_	_	_
52	B	_	NOUN	_	Number=Sing	_	_	_	_
53	)	_	PUNCT	_	_	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Resolution	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	complex	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	gel	_	NOUN	_	Number=Sing	_	_	_	_
11	shift	_	NOUN	_	Number=Sing	_	_	_	_
12	analysis	_	NOUN	_	Number=Sing	_	_	_	_
13	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	mobilized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	naive	_	ADJ	_	Degree=Pos	_	_	_	_
22	Mono	_	PROPN	_	Number=Sing	_	_	_	_
23	Mac	_	PROPN	_	Number=Sing	_	_	_	_
24	6	_	NUM	_	NumType=Card	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	consists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	mainly	_	ADV	_	_	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	p50-p65	_	NUM	_	NumType=Card	_	_	_	_
31	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	while	_	SCONJ	_	_	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	p50	_	NOUN	_	Number=Sing	_	_	_	_
40	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
41	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	predominant	_	ADJ	_	Degree=Pos	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	increase	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	p50	_	NUM	_	NumType=Card	_	_	_	_
5	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
6	coincides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	increase	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	p105	_	NUM	_	NumType=Card	_	_	_	_
12	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	suggestive	_	ADJ	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	up	_	ADP	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	regulation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	p50	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Reporter	_	NOUN	_	Number=Sing	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	reveals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	complex	_	NOUN	_	Number=Sing	_	_	_	_
12	mobilized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	functionally	_	ADV	_	_	_	_	_	_
18	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
28	constructs	_	NOUN	_	Number=Plur	_	_	_	_
29	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
33	virus	_	NOUN	_	Number=Sing	_	_	_	_
34	long	_	ADJ	_	Degree=Pos	_	_	_	_
35	terminal	_	NOUN	_	Number=Sing	_	_	_	_
36	repeat	_	NOUN	_	Number=Sing	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	TNF	_	PROPN	_	Number=Sing	_	_	_	_
40	5'-	_	NUM	_	NumType=Card	_	_	_	_
41	region	_	NOUN	_	Number=Sing	_	_	_	_
42	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
43	only	_	ADV	_	_	_	_	_	_
44	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
45	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
46	after	_	ADP	_	_	_	_	_	_
47	LPS	_	NOUN	_	Number=Sing	_	_	_	_
48	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	Mono	_	PROPN	_	Number=Sing	_	_	_	_
4	Mac	_	PROPN	_	Number=Sing	_	_	_	_
5	6	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	primary	_	ADJ	_	Degree=Pos	_	_	_	_
9	blood	_	NOUN	_	Number=Sing	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	when	_	ADV	_	PronType=Int	_	_	_	_
13	precultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	low	_	ADJ	_	Degree=Pos	_	_	_	_
17	dose	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	LPS	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	also	_	ADV	_	_	_	_	_	_
22	become	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
26	little	_	ADJ	_	Degree=Pos	_	_	_	_
27	TNF	_	NOUN	_	Number=Sing	_	_	_	_
28	after	_	ADP	_	_	_	_	_	_
29	LPS	_	NOUN	_	Number=Sing	_	_	_	_
30	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
3	blood	_	NOUN	_	Number=Sing	_	_	_	_
4	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	up	_	ADP	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	regulate	_	VERB	_	Degree=Pos	_	_	_	_
9	CD14	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
13	mobilize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	predominance	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	p50	_	NOUN	_	Number=Sing	_	_	_	_
23	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	LPS	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	post	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	involve	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	altered	_	VERB	_	Degree=Pos	_	_	_	_
22	composition	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	complex	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012299	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	NFAT1	_	PROPN	_	Number=Sing	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	P0	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	4	_	NUM	_	NumType=Card	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	4	_	NUM	_	NumType=Card	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	T	_	PROPN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	atopic	_	ADJ	_	Number=Sing	_	_	_	_
35	patients	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Allergen	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	atopic	_	ADJ	_	Number=Sing	_	_	_	_
5	patients	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	polarized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	producing	_	NOUN	_	Number=Sing	_	_	_	_

1	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
5	IgE	_	ADJ	_	Number=Sing	_	_	_	_
6	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	B	_	ADJ	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	basis	_	NOUN	_	Number=Sing	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	atopy	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	fully	_	ADV	_	_	_	_	_	_
16	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	general	_	ADJ	_	Degree=Pos	_	_	_	_
8	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	family	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	NFAT1	_	PROPN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	NFAT2	_	PROPN	_	Number=Sing	_	_	_	_
29	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	most	_	ADV	_	_	_	_	_	_
31	prominent	_	ADJ	_	Degree=Pos	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
34	T	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	unique	_	ADJ	_	Degree=Pos	_	_	_	_
5	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NFAT1	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	control	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	mouse	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	series	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
6	mobility	_	NOUN	_	Number=Sing	_	_	_	_
7	shift	_	NOUN	_	Number=Sing	_	_	_	_
8	assays	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	extracts	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	highly	_	ADV	_	_	_	_	_	_
14	polarized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	Th2	_	DET	_	Number=Sing	_	_	_	_
16	clones	_	NOUN	_	Number=Plur	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	atopics	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	clones	_	NOUN	_	Number=Plur	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	controls	_	NOUN	_	Number=Sing	_	_	_	_
24	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
25	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	DNA	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	binding	_	VERB	_	Number=Sing	_	_	_	_
29	activities	_	NOUN	_	Number=Plur	_	_	_	_
30	at	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	two	_	NUM	_	NumType=Card	_	_	_	_
33	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	binding	_	NOUN	_	Number=Sing	_	_	_	_
36	elements	_	NOUN	_	Number=Plur	_	_	_	_
37	P0	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	P1	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
43	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
44	human	_	ADJ	_	Degree=Pos	_	_	_	_
45	IL	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	4	_	NUM	_	NumType=Card	_	_	_	_
48	promoter	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	most	_	ADV	_	_	_	_	_	_
4	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
5	P0	_	NOUN	_	Number=Sing	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	complexes	_	NOUN	_	Number=Plur	_	_	_	_
12	devoid	_	ADJ	_	Degree=Pos	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NFAT2	_	PROPN	_	Number=Sing	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	readily	_	ADV	_	_	_	_	_	_
17	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	Th1	_	PROPN	_	Number=Sing	_	_	_	_
21	clones	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	hardly	_	ADV	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	Th2	_	NOUN	_	Number=Sing	_	_	_	_
30	clones	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	Th1	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Th2	_	DET	_	Number=Sing	_	_	_	_
9	clones	_	NOUN	_	Number=Plur	_	_	_	_
10	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	complexes	_	NOUN	_	Number=Plur	_	_	_	_
14	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	strongly	_	ADV	_	_	_	_	_	_
16	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	P1	_	NOUN	_	Number=Sing	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	consisting	_	VERB	_	VerbForm=Ger	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NFAT2	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	P0	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	compatible	_	ADJ	_	Degree=Pos	_	_	_	_
30	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
31	activity	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	without	_	ADP	_	_	_	_	_	_
34	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
35	differences	_	NOUN	_	Number=Plur	_	_	_	_
36	between	_	ADP	_	_	_	_	_	_
37	Th1	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	Th2	_	DET	_	Number=Sing	_	_	_	_
40	clones	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Like	_	ADP	_	_	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	clones	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	P0	_	NOUN	_	Number=Sing	_	_	_	_
10	complex	_	ADJ	_	Number=Sing	_	_	_	_
11	formation	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
18	level	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
21	blood	_	NOUN	_	Number=Sing	_	_	_	_
22	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	three	_	NUM	_	NumType=Card	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	five	_	NUM	_	NumType=Card	_	_	_	_
31	severe	_	ADJ	_	Degree=Pos	_	_	_	_
32	atopic	_	ADJ	_	Degree=Pos	_	_	_	_
33	dermatitis	_	NOUN	_	Number=Sing	_	_	_	_
34	patients	_	NOUN	_	Number=Plur	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	strongly	_	ADV	_	_	_	_	_	_
37	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	serum	_	NOUN	_	Number=Sing	_	_	_	_
39	IgE	_	NOUN	_	Number=Sing	_	_	_	_
40	levels	_	NOUN	_	Number=Plur	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	but	_	CCONJ	_	_	_	_	_	_
43	not	_	PART	_	_	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	control	_	NOUN	_	Number=Sing	_	_	_	_
46	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	high	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	level	_	NOUN	_	Number=Sing	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	atopic	_	PROPN	_	Number=Sing	_	_	_	_

1	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	selective	_	ADJ	_	Degree=Pos	_	_	_	_
7	reduction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	suppressive	_	ADJ	_	Degree=Pos	_	_	_	_
10	NFAT1	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	P0	_	NOUN	_	Number=Sing	_	_	_	_
18	element	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	some	_	DET	_	_	_	_	_	_
22	patients	_	NOUN	_	Number=Plur	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	multifactorial	_	ADJ	_	Degree=Pos	_	_	_	_
26	disease	_	NOUN	_	Number=Sing	_	_	_	_
27	may	_	AUX	_	VerbForm=Fin	_	_	_	_
28	have	_	VERB	_	VerbForm=Inf	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	putative	_	ADJ	_	Degree=Pos	_	_	_	_
31	systemic	_	ADJ	_	Degree=Pos	_	_	_	_
32	disorder	_	NOUN	_	Number=Sing	_	_	_	_
33	at	_	ADP	_	_	_	_	_	_
34	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
35	level	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012307	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Platelet	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	activating	_	ADJ	_	VerbForm=Ger	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	phospholipid	_	ADJ	_	Degree=Pos	_	_	_	_
7	turnover	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	calcium	_	NOUN	_	Number=Sing	_	_	_	_
10	flux	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	arachidonic	_	ADJ	_	Number=Sing	_	_	_	_
13	acid	_	ADJ	_	Number=Sing	_	_	_	_
14	liberation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	eicosanoid	_	ADJ	_	Degree=Pos	_	_	_	_
17	generation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	oncogene	_	ADJ	_	Degree=Pos	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	line	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Platelet	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	potent	_	ADJ	_	Degree=Pos	_	_	_	_
8	mediator	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	actions	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	platelet	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	activating	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	centered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	mainly	_	ADV	_	_	_	_	_	_
13	around	_	ADP	_	_	_	_	_	_
14	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	platelets	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	begin	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	uncover	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	influence	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	platelet	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Employing	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	EBV	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	line	_	NOUN	_	Number=Sing	_	_	_	_
10	SKW6.4	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	platelet	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	significantly	_	ADV	_	_	_	_	_	_
20	alters	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	membrane	_	NOUN	_	Number=Sing	_	_	_	_
22	phospholipid	_	ADJ	_	Degree=Pos	_	_	_	_
23	metabolism	_	NOUN	_	Number=Sing	_	_	_	_
24	indicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	incorporation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	32P	_	NUM	_	Number=Sing	_	_	_	_
30	into	_	ADP	_	_	_	_	_	_
31	phosphatidylcholine	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	phosphatidylinositol	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	phosphatidic	_	ADJ	_	Degree=Pos	_	_	_	_
37	acid	_	NOUN	_	Number=Sing	_	_	_	_
38	but	_	CCONJ	_	_	_	_	_	_
39	not	_	PART	_	_	_	_	_	_
40	significantly	_	ADV	_	_	_	_	_	_
41	into	_	ADP	_	_	_	_	_	_
42	phosphatidylethanolamine	_	NOUN	_	Number=Sing	_	_	_	_
43	at	_	ADP	_	_	_	_	_	_
44	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
45	ranging	_	VERB	_	VerbForm=Ger	_	_	_	_
46	from	_	ADP	_	_	_	_	_	_
47	10	_	NUM	_	NumType=Card	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	-	_	SYM	_	_	_	_	_	_
50	9	_	NUM	_	NumType=Card	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	to	_	ADP	_	_	_	_	_	_
53	10	_	NUM	_	NumType=Card	_	_	_	_
54	(-6	_	NUM	_	NumType=Card	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	M.	_	PROPN	_	Number=Sing	_	_	_	_
57	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
58	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
59	precursor	_	NOUN	_	Number=Sing	_	_	_	_
60	,	_	PUNCT	_	_	_	_	_	_
61	lyso	_	ADJ	_	Number=Sing	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	platelet	_	NOUN	_	Number=Sing	_	_	_	_
64	-	_	PUNCT	_	_	_	_	_	_
65	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
66	factor	_	NOUN	_	Number=Sing	_	_	_	_
67	,	_	PUNCT	_	_	_	_	_	_
68	at	_	ADP	_	_	_	_	_	_
69	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
70	concentration	_	NOUN	_	Number=Sing	_	_	_	_
71	as	_	ADV	_	_	_	_	_	_
72	high	_	ADJ	_	Degree=Pos	_	_	_	_
73	as	_	ADP	_	_	_	_	_	_
74	10	_	NUM	_	NumType=Card	_	_	_	_
75	(	_	PUNCT	_	_	_	_	_	_
76	-	_	SYM	_	_	_	_	_	_
77	7	_	NUM	_	NumType=Card	_	_	_	_
78	)	_	PUNCT	_	_	_	_	_	_
79	M	_	NUM	_	Number=Sing	_	_	_	_
80	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
81	no	_	DET	_	_	_	_	_	_
82	effect	_	NOUN	_	Number=Sing	_	_	_	_
83	on	_	ADP	_	_	_	_	_	_
84	any	_	DET	_	_	_	_	_	_
85	of	_	ADP	_	_	_	_	_	_
86	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
87	membrane	_	NOUN	_	Number=Sing	_	_	_	_
88	phospholipids	_	NOUN	_	Number=Plur	_	_	_	_
89	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	platelet	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	10	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	-	_	SYM	_	_	_	_	_	_
13	12	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	10	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	-6	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	M	_	NUM	_	NumType=Card	_	_	_	_
21	induced	_	VERB	_	_	_	_	_	_
22	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	significant	_	ADJ	_	Degree=Pos	_	_	_	_
25	elevation	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
28	calcium	_	NOUN	_	Number=Sing	_	_	_	_
29	levels	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	whereas	_	SCONJ	_	_	_	_	_	_
32	lyso	_	ADJ	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	platelet	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	activating	_	ADJ	_	VerbForm=Ger	_	_	_	_
37	factor	_	NOUN	_	Number=Sing	_	_	_	_
38	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
39	again	_	ADV	_	_	_	_	_	_
40	ineffective	_	ADJ	_	Degree=Pos	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	impact	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	platelet	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	B	_	VERB	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	by	_	SCONJ	_	_	_	_	_	_
16	measuring	_	VERB	_	VerbForm=Ger	_	_	_	_
17	platelet	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	activating	_	ADJ	_	VerbForm=Ger	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	arachidonic	_	ADJ	_	Number=Sing	_	_	_	_
23	acid	_	NOUN	_	Number=Sing	_	_	_	_
24	release	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	5	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	hydroxyeicosatetraenoic	_	ADJ	_	Degree=Pos	_	_	_	_
29	acid	_	NOUN	_	Number=Sing	_	_	_	_
30	production	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	platelet	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	activating	_	ADJ	_	VerbForm=Ger	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	capable	_	ADJ	_	Degree=Pos	_	_	_	_
9	of	_	SCONJ	_	_	_	_	_	_
10	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	proto	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	oncogenes	_	NOUN	_	Number=Sing	_	_	_	_
18	c	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	fos	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	explored	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	possible	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	hydroxyeicosatetraenoic	_	ADJ	_	Degree=Pos	_	_	_	_
11	acid	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	regulator	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	arachidonic	_	ADJ	_	Degree=Pos	_	_	_	_
17	acid	_	ADJ	_	Number=Sing	_	_	_	_
18	liberation	_	NOUN	_	Number=Sing	_	_	_	_
19	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
22	5	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	lipoxygenase	_	NOUN	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	modulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	platelet	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	arachidonic	_	ADJ	_	Degree=Pos	_	_	_	_
33	acid	_	NOUN	_	Number=Sing	_	_	_	_
34	release	_	NOUN	_	Number=Sing	_	_	_	_
35	perhaps	_	ADV	_	_	_	_	_	_
36	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
37	at	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	level	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	phospholipase	_	NOUN	_	Number=Sing	_	_	_	_
42	A2	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	summary	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	platelet	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	here	_	ADV	_	PronType=Dem	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	have	_	VERB	_	VerbForm=Inf	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	direct	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	profound	_	ADJ	_	Degree=Pos	_	_	_	_
17	effect	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	pure	_	ADJ	_	Degree=Pos	_	_	_	_
21	B	_	NOUN	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012308	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	redox	_	NOUN	_	Number=Sing	_	_	_	_
12	imbalance	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	implicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
9	thiols	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	regulation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
25	molecules	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	designed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
7	whether	_	SCONJ	_	_	_	_	_	_
8	changes	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	GSH	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	oxidized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	GSSG	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	can	_	AUX	_	VerbForm=Fin	_	_	_	_
23	alter	_	VERB	_	VerbForm=Inf	_	_	_	_
24	neutrophil	_	NOUN	_	Degree=Pos	_	_	_	_
25	adhesivity	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	define	_	VERB	_	VerbForm=Inf	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
31	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
32	that	_	PRON	_	PronType=Rel	_	_	_	_
33	underlies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
35	GSSG	_	NOUN	_	Number=Sing	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	GSH	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
41	response	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
5	vein	_	NOUN	_	Number=Sing	_	_	_	_
6	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HUVEC	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	monolayers	_	NOUN	_	Number=Plur	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	6	_	NUM	_	NumType=Card	_	_	_	_
14	hours	_	NOUN	_	Number=Plur	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	0.2	_	NUM	_	NumType=Card	_	_	_	_
17	mmol	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	L	_	NOUN	_	Number=Sing	_	_	_	_
20	diamide	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	mmol	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	L	_	NOUN	_	Number=Sing	_	_	_	_
26	buthionine	_	NOUN	_	Number=Sing	_	_	_	_
27	sulfoximine	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	BSO	_	PROPN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	GSH	_	NOUN	_	Number=Sing	_	_	_	_
33	levels	_	NOUN	_	Number=Plur	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	ratio	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	GSSG	_	NOUN	_	Number=Sing	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	GSH	_	NOUN	_	Number=Sing	_	_	_	_
42	without	_	ADP	_	_	_	_	_	_
43	cell	_	NOUN	_	Number=Sing	_	_	_	_
44	toxicity	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	redox	_	NOUN	_	Degree=Pos	_	_	_	_
3	changes	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	similar	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	anoxia	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	reoxygenation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Diamide	_	ADJ	_	Number=Sing	_	_	_	_
2	plus	_	CCONJ	_	_	_	_	_	_
3	BSO	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	thiol	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	disulfide	_	NOUN	_	Degree=Pos	_	_	_	_
9	imbalance	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	biphasic	_	ADJ	_	Degree=Pos	_	_	_	_
15	increase	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
18	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	peak	_	NOUN	_	Number=Sing	_	_	_	_
23	responses	_	NOUN	_	Number=Plur	_	_	_	_
24	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	at	_	ADP	_	_	_	_	_	_
26	15	_	NUM	_	NumType=Card	_	_	_	_
27	minutes	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	phase	_	NOUN	_	Number=Sing	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	240	_	NUM	_	NumType=Card	_	_	_	_
34	minutes	_	NOUN	_	Number=Plur	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	phase	_	NOUN	_	Number=Sing	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	N	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Acetylcysteine	_	PROPN	_	Number=Sing	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	attenuated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
7	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	both	_	DET	_	_	_	_	_	_
10	phases	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	GSH	_	PROPN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
21	responses	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	phase	_	NOUN	_	Number=Sing	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	inversely	_	ADV	_	_	_	_	_	_
8	correlated	_	ADJ	_	Degree=Pos	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	GSH	_	NOUN	_	Number=Sing	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	GSSG	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	GSH	_	NOUN	_	Number=Sing	_	_	_	_
19	ratio	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whereas	_	SCONJ	_	_	_	_	_	_
22	phase	_	NOUN	_	Number=Sing	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	neutrophil	_	NOUN	_	Degree=Pos	_	_	_	_
25	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	positively	_	ADV	_	_	_	_	_	_
28	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	GSSG	_	NOUN	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	GSH	_	NOUN	_	Number=Sing	_	_	_	_
33	ratio	_	NOUN	_	Number=Sing	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	not	_	ADV	_	_	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	GSH	_	NOUN	_	Number=Sing	_	_	_	_
38	levels	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
3	molecule	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	P-selectin	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
11	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
12	attenuated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	neutrophil	_	ADJ	_	Number=Sing	_	_	_	_
16	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	both	_	CCONJ	_	_	_	_	_	_
19	phases	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whereas	_	SCONJ	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	anti-E	_	ADJ	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	selectin	_	ADJ	_	Number=Sing	_	_	_	_
26	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
27	antibody	_	NOUN	_	Number=Sing	_	_	_	_
28	also	_	ADV	_	_	_	_	_	_
29	attenuated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	phase	_	NOUN	_	Number=Sing	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	response	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	actinomycin	_	NOUN	_	Number=Sing	_	_	_	_
4	D	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	competing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	ds	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	activator	_	NOUN	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	cognate	_	NOUN	_	Number=Sing	_	_	_	_
25	DNA	_	PROPN	_	Number=Sing	_	_	_	_
26	sequences	_	NOUN	_	Number=Plur	_	_	_	_
27	significantly	_	ADV	_	_	_	_	_	_
28	attenuated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	phase	_	NOUN	_	Number=Sing	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	response	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	which	_	PRON	_	PronType=Rel	_	_	_	_
35	implicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	role	_	NOUN	_	Number=Sing	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	de	_	PROPN	_	Number=Sing	_	_	_	_
40	novo	_	PROPN	_	Number=Sing	_	_	_	_
41	protein	_	NOUN	_	Number=Sing	_	_	_	_
42	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Surface	_	NOUN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
5	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
6	molecule	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	P	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	selectin	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	E-selectin	_	NOUN	_	Number=Sing	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	HUVECs	_	NOUN	_	Number=Sing	_	_	_	_
18	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	phase	_	NOUN	_	Number=Sing	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
26	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
27	responses	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	changes	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	GSSG	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	GSH	_	NOUN	_	Number=Sing	_	_	_	_
12	cause	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	independent	_	ADJ	_	Degree=Pos	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	surface	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	different	_	ADJ	_	Degree=Pos	_	_	_	_
24	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
27	molecules	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	phase	_	NOUN	_	Number=Sing	_	_	_	_
36	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
39	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
40	response	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012311	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Alpha	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	tocopherol	_	NOUN	_	Number=Sing	_	_	_	_
4	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
5	agonist	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	cultured	_	VERB	_	VerbForm=Inf	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	proposed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	anti-atherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
8	agents	_	NOUN	_	Number=Plur	_	_	_	_
9	;	_	PUNCT	_	_	_	_	_	_
10	however	_	ADV	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
14	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
15	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	beneficial	_	ADJ	_	Degree=Pos	_	_	_	_
17	effects	_	NOUN	_	Number=Plur	_	_	_	_
18	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	poorly	_	ADV	_	_	_	_	_	_
20	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	tocopherol	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	tcp	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	one	_	NUM	_	NumType=Card	_	_	_	_
17	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	event	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	atherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
21	plaque	_	NOUN	_	Number=Sing	_	_	_	_
22	development	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
25	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	stimulated	_	VERB	_	VerbForm=Inf	_	_	_	_
28	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	ECs	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
3	vein	_	NOUN	_	Number=Sing	_	_	_	_
4	ECs	_	PROPN	_	Number=Sing	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	pretreated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	tcp	_	NOUN	_	Number=Sing	_	_	_	_
11	before	_	ADP	_	_	_	_	_	_
12	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	agonists	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
18	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	10	_	NUM	_	NumType=Card	_	_	_	_
25	ng	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	ml	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	LPS	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	10	_	NUM	_	NumType=Card	_	_	_	_
33	ng	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	ml	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	thrombin	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	30	_	NUM	_	NumType=Card	_	_	_	_
41	U/ml	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	or	_	CCONJ	_	_	_	_	_	_
45	PMA	_	PROPN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	10	_	NUM	_	NumType=Card	_	_	_	_
48	nM	_	NOUN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Agonist	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	not	_	ADV	_	_	_	_	_	_
10	basal	_	ADJ	_	Degree=Pos	_	_	_	_
11	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	time	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	concentration	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	manner	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	tcp	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IC50	_	PROPN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	tcp	_	NOUN	_	Number=Sing	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	45	_	NUM	_	NumType=Card	_	_	_	_
17	microM	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	decrease	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	steady	_	ADJ	_	Degree=Pos	_	_	_	_
9	state	_	NOUN	_	Number=Sing	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	E	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	selectin	_	NOUN	_	Number=Sing	_	_	_	_
15	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	surface	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	E	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	selectin	_	NOUN	_	Number=Sing	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	ability	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
33	antibody	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	E	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	selectin	_	NOUN	_	Number=Sing	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
40	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
45	system	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Probucol	_	NOUN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	50	_	NUM	_	NumType=Card	_	_	_	_
4	microM	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	N-acetylcysteine	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	20	_	NUM	_	NumType=Card	_	_	_	_
10	mM	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	agonist	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
20	;	_	PUNCT	_	_	_	_	_	_
21	whereas	_	ADV	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	several	_	ADJ	_	Degree=Pos	_	_	_	_
24	other	_	ADJ	_	Degree=Pos	_	_	_	_
25	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
26	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	no	_	DET	_	_	_	_	_	_
28	significant	_	ADJ	_	Degree=Pos	_	_	_	_
29	effect	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	PROPN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	C	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	PKC	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	appear	_	VERB	_	VerbForm=Inf	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	play	_	VERB	_	VerbForm=Inf	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	tcp	_	NOUN	_	Number=Sing	_	_	_	_
19	effect	_	NOUN	_	Number=Sing	_	_	_	_
20	since	_	SCONJ	_	_	_	_	_	_
21	no	_	DET	_	_	_	_	_	_
22	suppression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	PKC	_	NOUN	_	Number=Sing	_	_	_	_
27	substrates	_	NOUN	_	Number=Plur	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	PROPN	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	E	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	selectin	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	EC	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	show	_	VERB	_	VerbForm=Inf	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	tcp	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	decrease	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	after	_	ADP	_	_	_	_	_	_
22	cytokine	_	ADJ	_	Number=Sing	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	hypothesized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	tcp	_	NOUN	_	Number=Sing	_	_	_	_
9	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	anti-atherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
13	molecule	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	SCONJ	_	_	_	_	_	_
15	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
16	generation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	oxidized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	LDL	_	NOUN	_	Number=Sing	_	_	_	_
20	--	_	PUNCT	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	putative	_	ADJ	_	Degree=Pos	_	_	_	_
23	triggering	_	VERB	_	VerbForm=Ger	_	_	_	_
24	molecule	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	atherosclerotic	_	ADJ	_	Degree=Pos	_	_	_	_
28	process	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	point	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	novel	_	NOUN	_	Number=Sing	_	_	_	_
7	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
8	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	action	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	tcp	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012317	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CD14	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
4	translocation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
14	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	require	_	VERB	_	VerbForm=Inf	_	_	_	_
17	tyrosine	_	ADJ	_	Degree=Pos	_	_	_	_
18	kinase	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	During	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	course	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	serious	_	ADJ	_	Degree=Pos	_	_	_	_
6	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
7	infections	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	LPS	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
19	receptors	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	generation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	mediators	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	systemic	_	ADJ	_	Degree=Pos	_	_	_	_
30	symptoms	_	NOUN	_	Number=Plur	_	_	_	_
31	including	_	VERB	_	VerbForm=Ger	_	_	_	_
32	hemodynamic	_	ADJ	_	Degree=Pos	_	_	_	_
33	instability	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	shock	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	CD14	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	glycosylphosphatidylinositol	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	antigen	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	functions	_	NOUN	_	Number=Plur	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	LPS	_	NOUN	_	Number=Sing	_	_	_	_
13	signaling	_	NOUN	_	Number=Sing	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	critical	_	ADJ	_	Degree=Pos	_	_	_	_
3	issue	_	NOUN	_	Number=Sing	_	_	_	_
4	concerns	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	CD14	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	no	_	DET	_	_	_	_	_	_
14	transmembrane	_	NOUN	_	Number=Sing	_	_	_	_
15	domain	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	transduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	signal	_	NOUN	_	Number=Sing	_	_	_	_
20	following	_	VERB	_	VerbForm=Ger	_	_	_	_
21	LPS	_	PROPN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	investigators	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	hypothesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	CD14	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	signaling	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	effected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	through	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
19	kinase	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	TK	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	multicomponent	_	ADJ	_	Degree=Pos	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	model	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	LPS	_	NOUN	_	Number=Sing	_	_	_	_
31	signaling	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Wild	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	type	_	VERB	_	Number=Sing	_	_	_	_
4	Chinese	_	ADJ	_	Degree=Pos	_	_	_	_
5	hamster	_	NOUN	_	Number=Sing	_	_	_	_
6	ovary	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	CHO	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	K1	_	NUM	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	can	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	release	_	VERB	_	VerbForm=Inf	_	_	_	_
20	arachidonate	_	NOUN	_	Number=Sing	_	_	_	_
21	following	_	VERB	_	VerbForm=Ger	_	_	_	_
22	transfection	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	CD14	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	CHO	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	CD14	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	translocation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cytosolic	_	ADJ	_	Number=Sing	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	number	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	LPS	_	NOUN	_	Number=Plur	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
18	responses	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	sought	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
5	if	_	SCONJ	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	pathway	_	NOUN	_	Number=Sing	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	present	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	CHO	_	PROPN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	CD14	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	elucidate	_	VERB	_	VerbForm=Inf	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	relationship	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	CD14	_	PROPN	_	Number=Sing	_	_	_	_
29	receptor	_	NOUN	_	Number=Sing	_	_	_	_
30	system	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	translocation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	CHO	_	PROPN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	CD14	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	resembled	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	same	_	ADJ	_	Degree=Pos	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	murine	_	NOUN	_	Number=Sing	_	_	_	_
22	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	like	_	ADP	_	Degree=Pos	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	line	_	NOUN	_	Number=Sing	_	_	_	_
27	RAW	_	NOUN	_	Number=Sing	_	_	_	_
28	264.7	_	NUM	_	NumType=Card	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
3	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	corticosteroids	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	suppress	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	arachidonate	_	NOUN	_	Number=Sing	_	_	_	_
10	release	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	no	_	DET	_	_	_	_	_	_
20	effect	_	NOUN	_	Number=Sing	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	translocation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	CHO	_	PROPN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	CD14	_	PROPN	_	Number=Sing	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	RAW	_	PROPN	_	Number=Sing	_	_	_	_
34	264.7	_	NUM	_	NumType=Card	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
38	that	_	SCONJ	_	_	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappa	_	NOUN	_	Number=Sing	_	_	_	_
42	B	_	NOUN	_	Number=Sing	_	_	_	_
43	translocation	_	NOUN	_	Number=Sing	_	_	_	_
44	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
46	early	_	ADJ	_	Degree=Pos	_	_	_	_
47	event	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	TK	_	PROPN	_	Number=Sing	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	consistently	_	ADV	_	_	_	_	_	_
6	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	immunoblotting	_	ADJ	_	VerbForm=Ger	_	_	_	_
9	extracts	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	RAW	_	PROPN	_	Number=Sing	_	_	_	_
13	264.7	_	NUM	_	NumType=Card	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	LPS	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	phosphotyrosine	_	NOUN	_	Number=Sing	_	_	_	_
20	residues	_	NOUN	_	Number=Plur	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	similarly	_	ADV	_	_	_	_	_	_
26	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	CHO	_	PROPN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	CD14	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	TK	_	PROPN	_	Number=Sing	_	_	_	_
5	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
6	herbimycin	_	VERB	_	Number=Sing	_	_	_	_
7	A	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	genistein	_	PROPN	_	Number=Sing	_	_	_	_
10	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
13	translocation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	CHO	_	PROPN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	CD14	_	PROPN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	RAW	_	PROPN	_	Number=Sing	_	_	_	_
25	264.7	_	NUM	_	NumType=Card	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	although	_	SCONJ	_	_	_	_	_	_
29	both	_	DET	_	_	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
32	agents	_	NOUN	_	Number=Plur	_	_	_	_
33	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	LPS	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	TK	_	NOUN	_	Number=Sing	_	_	_	_
38	activity	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	RAW	_	PROPN	_	Number=Sing	_	_	_	_
41	264.7	_	NUM	_	NumType=Card	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	imply	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TK	_	PROPN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	obligatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	CD14	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	mediated	_	VERB	_	Degree=Pos	_	_	_	_
14	signal	_	NOUN	_	Number=Sing	_	_	_	_
15	transduction	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	LPS	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012318	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Itk	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	T	_	NUM	_	NumType=Card	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
9	kinase	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	CD2	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	line	_	NOUN	_	Number=Sing	_	_	_	_
28	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	functional	_	ADJ	_	Degree=Pos	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Itk	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	member	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
14	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	Tec	_	PROPN	_	Number=Sing	_	_	_	_
17	family	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	either	_	CCONJ	_	_	_	_	_	_
4	CD2	_	NOUN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	T	_	NUM	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	TCR	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	CD3	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	Tcells	_	NOUN	_	Number=Plur	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
18	antibody	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	cross	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
26	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	Itk	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	which	_	PRON	_	PronType=Rel	_	_	_	_
31	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
32	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
33	as	_	ADV	_	_	_	_	_	_
34	early	_	ADV	_	Degree=Pos	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	min	_	NOUN	_	Number=Plur	_	_	_	_
38	after	_	ADP	_	_	_	_	_	_
39	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
3	kinase	_	NOUN	_	Number=Sing	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	anti-Itk	_	ADJ	_	Degree=Pos	_	_	_	_
8	immunoprecipitate	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	significantly	_	ADV	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	upon	_	ADP	_	_	_	_	_	_
13	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	stimulations	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-2	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	X	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	cross	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	linking	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	CD2	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	TCR	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	CD3	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	CD28	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	significantly	_	ADV	_	_	_	_	_	_
27	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	transient	_	ADJ	_	Degree=Pos	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	Itk	_	NOUN	_	Number=Sing	_	_	_	_
34	mutant	_	NOUN	_	Number=Sing	_	_	_	_
35	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	kinase	_	NOUN	_	Number=Sing	_	_	_	_
38	activity	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	reduction	_	NOUN	_	Number=Sing	_	_	_	_
3	paralleled	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	decrease	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
8	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
11	wild	_	ADJ	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	type	_	VERB	_	Number=Sing	_	_	_	_
14	Itk	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CD2	_	NOUN	_	Number=Sing	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	TCR	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	CD3	_	PROPN	_	Number=Sing	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	which	_	PRON	_	PronType=Rel	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	included	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	impaired	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	Itk	_	PROPN	_	Number=Sing	_	_	_	_
13	mutant	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Itk	_	PROPN	_	Number=Sing	_	_	_	_
6	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	critical	_	ADJ	_	Degree=Pos	_	_	_	_
18	involvement	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Itk	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	initial	_	ADJ	_	Degree=Pos	_	_	_	_
24	stage	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	T	_	PROPN	_	Number=Sing	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
31	signals	_	NOUN	_	Number=Plur	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	TCR	_	NOUN	_	Number=Sing	_	_	_	_
35	/	_	PUNCT	_	_	_	_	_	_
36	CD3	_	PROPN	_	Number=Sing	_	_	_	_
37	complex	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	CD2	_	PROPN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	CD28	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012321	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Involvement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
5	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
15	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	chain	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	addition	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	highly	_	ADV	_	_	_	_	_	_
11	conserved	_	ADJ	_	Degree=Pos	_	_	_	_
12	octamer	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	OCTA	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
18	motif	_	NOUN	_	Number=Sing	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	important	_	ADJ	_	Degree=Pos	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
29	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	chain	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	IgH	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
38	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	effect	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	SCONJ	_	_	_	_	_	_
43	mutating	_	VERB	_	VerbForm=Ger	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	binding	_	NOUN	_	Number=Sing	_	_	_	_
46	site	_	NOUN	_	Number=Sing	_	_	_	_
47	for	_	ADP	_	_	_	_	_	_
48	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
49	putative	_	ADJ	_	Degree=Pos	_	_	_	_
50	additional	_	ADJ	_	Degree=Pos	_	_	_	_
51	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	specific	_	ADJ	_	Degree=Pos	_	_	_	_
54	transcription	_	NOUN	_	Number=Sing	_	_	_	_
55	factor	_	NOUN	_	Number=Sing	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
58	NF	_	PROPN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	microB	_	NOUN	_	Number=Sing	_	_	_	_
61	,	_	PUNCT	_	_	_	_	_	_
62	in	_	ADP	_	_	_	_	_	_
63	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
64	murine	_	NOUN	_	Number=Sing	_	_	_	_
65	IgH	_	NOUN	_	Number=Sing	_	_	_	_
66	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	microB	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	critical	_	ADJ	_	Degree=Pos	_	_	_	_
14	role	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	IgH	_	PROPN	_	Number=Sing	_	_	_	_
18	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	because	_	SCONJ	_	_	_	_	_	_
21	mutation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	microB	_	PROPN	_	Number=Sing	_	_	_	_
25	DNA	_	PROPN	_	Number=Sing	_	_	_	_
26	motif	_	NOUN	_	Number=Sing	_	_	_	_
27	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	IgH	_	PROPN	_	Number=Sing	_	_	_	_
33	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	lineage	_	NOUN	_	Number=Sing	_	_	_	_
42	but	_	CCONJ	_	_	_	_	_	_
43	not	_	ADV	_	_	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	nonlymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	even	_	ADV	_	_	_	_	_	_
8	stronger	_	ADJ	_	Degree=Cmp	_	_	_	_
9	than	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	effect	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	mutation	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	OCTA	_	PROPN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	mutation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	microB	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	OCTA	_	PROPN	_	Number=Sing	_	_	_	_
10	sites	_	NOUN	_	Number=Plur	_	_	_	_
11	further	_	ADV	_	_	_	_	_	_
12	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	alteration	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	either	_	CCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	microB	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	E3	_	PROPN	_	Number=Sing	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	70	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	base	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	pair	_	NOUN	_	Number=Sing	_	_	_	_
18	fragment	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IgH	_	PROPN	_	Number=Sing	_	_	_	_
22	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	lacks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	site	_	NOUN	_	Number=Sing	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	OCTA	_	PROPN	_	Number=Sing	_	_	_	_
30	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
32	activity	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	completely	_	ADV	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Nevertheless	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	multimer	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	microB	_	NOUN	_	Number=Sing	_	_	_	_
8	motif	_	NOUN	_	Number=Sing	_	_	_	_
9	alone	_	ADV	_	_	_	_	_	_
10	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	no	_	DET	_	_	_	_	_	_
12	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	DNase	_	PROPN	_	Number=Sing	_	_	_	_
2	footprinting	_	VERB	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	corroborated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	functional	_	ADJ	_	Degree=Pos	_	_	_	_
7	data	_	NOUN	_	Number=Sing	_	_	_	_
8	showing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	binds	_	NOUN	_	Number=Plur	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	microB	_	NOUN	_	Number=Sing	_	_	_	_
19	DNA	_	PROPN	_	Number=Sing	_	_	_	_
20	motif	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	microB	_	NOUN	_	Number=Sing	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	new	_	ADJ	_	Degree=Pos	_	_	_	_
11	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	important	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IgH	_	ADJ	_	Degree=Pos	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	interaction	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	another	_	DET	_	_	_	_	_	_
28	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
29	element	_	NOUN	_	Number=Sing	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	essential	_	ADJ	_	Degree=Pos	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	activity	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012328	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	during	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	immune	_	ADJ	_	Degree=Pos	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Cytokine	_	ADJ	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	immune	_	ADJ	_	Degree=Pos	_	_	_	_
5	system	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	regulation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	immune	_	ADJ	_	Degree=Pos	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	encounter	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	antigen	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	naive	_	ADJ	_	Degree=Pos	_	_	_	_
8	CD4	_	NOUN	_	Number=Sing	_	_	_	_
9	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	helper	_	VERB	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	Th	_	X	_	_	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	differentiate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	into	_	ADP	_	_	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	effector	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	types	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	effector	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
9	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
13	profiles	_	NOUN	_	Number=Plur	_	_	_	_
14	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	produce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	IFN	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	gamma	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	whereas	_	ADV	_	_	_	_	_	_

1	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	produce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	5	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	6	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	10	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	13	_	NUM	_	NumType=Card	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	many	_	ADJ	_	Degree=Pos	_	_	_	_
3	pathological	_	ADJ	_	Degree=Pos	_	_	_	_
4	situations	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	balance	_	NOUN	_	Number=Sing	_	_	_	_
8	between	_	ADP	_	_	_	_	_	_
9	Th1	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	Th2	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	immune	_	ADJ	_	Number=Sing	_	_	_	_
13	responses	_	NOUN	_	Number=Plur	_	_	_	_
14	determines	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	outcome	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
19	immunologically	_	ADV	_	_	_	_	_	_
20	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
21	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
22	syndromes	_	NOUN	_	Number=Plur	_	_	_	_
23	including	_	VERB	_	VerbForm=Ger	_	_	_	_
24	infectious	_	ADJ	_	Degree=Pos	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	autoimmune	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	allergic	_	ADJ	_	Degree=Pos	_	_	_	_
30	diseases	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
5	basis	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	tissue	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Th1	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	Th2	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	like	_	ADJ	_	Degree=Pos	_	_	_	_
18	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
19	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	remained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	elusive	_	ADJ	_	Degree=Pos	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	review	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	evaluate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	possible	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	vivo	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	different	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	T	_	PROPN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	immune	_	ADJ	_	Degree=Pos	_	_	_	_
25	response	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012330	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	P	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	regulatory	_	ADJ	_	Number=Sing	_	_	_	_
16	P	_	NOUN	_	Number=Sing	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	5'-	_	NUM	_	NumType=Card	_	_	_	_
20	CGAAAATTTCC	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	3	_	NUM	_	NumType=Card	_	_	_	_
23	'	_	NOUN	_	_	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	4	_	NUM	_	NumType=Card	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	:	_	PUNCT	_	_	_	_	_	_
33	relationship	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	PROPN	_	Number=Sing	_	_	_	_
38	B	_	PROPN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	AT	_	PROPN	_	_	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	P	_	NOUN	_	Number=Sing	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	4	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	as	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
23	element	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
26	12	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	myristate	_	NOUN	_	Number=Sing	_	_	_	_
29	13	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	acetate	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	calcium	_	NOUN	_	Number=Sing	_	_	_	_
34	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	A23187	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
40	T	_	NOUN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	shares	_	NOUN	_	Number=Plur	_	_	_	_
44	sequence	_	NOUN	_	Number=Sing	_	_	_	_
45	similarity	_	NOUN	_	Number=Sing	_	_	_	_
46	with	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	NF	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	kappa	_	NOUN	_	Number=Sing	_	_	_	_
51	B	_	NOUN	_	Number=Sing	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	NF	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	AT	_	ADP	_	_	_	_	_	_
57	binding	_	NOUN	_	Number=Sing	_	_	_	_
58	sites	_	NOUN	_	Number=Plur	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	P	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	P	_	NOUN	_	Number=Sing	_	_	_	_
16	sequence	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	related	_	ADJ	_	Degree=Pos	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	PROPN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	AT	_	PROPN	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	P65	_	NUM	_	Number=Sing	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	P65/P50	_	NUM	_	NumType=Card	_	_	_	_
9	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	bound	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	P	_	NOUN	_	Number=Sing	_	_	_	_
15	sequence	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
18	mobility	_	NOUN	_	Number=Sing	_	_	_	_
19	shift	_	NOUN	_	Number=Sing	_	_	_	_
20	assays	_	NOUN	_	Number=Plur	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	EMSA	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	through	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	P	_	NOUN	_	Number=Sing	_	_	_	_
30	sequence	_	NOUN	_	Number=Sing	_	_	_	_
31	when	_	ADV	_	PronType=Int	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
34	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	cotransfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	P	_	NOUN	_	Number=Sing	_	_	_	_
38	sequence	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	reporter	_	NOUN	_	Number=Sing	_	_	_	_
42	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
45	T	_	PROPN	_	Number=Sing	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	EMSAs	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	P	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	unlabeled	_	ADJ	_	Degree=Pos	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	AT	_	ADP	_	_	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	unlabeled	_	ADJ	_	Degree=Pos	_	_	_	_
24	AP1	_	NOUN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	site	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	AT	_	PROPN	_	_	_	_	_	_
32	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	activity	_	NOUN	_	Number=Sing	_	_	_	_
35	that	_	PRON	_	PronType=Rel	_	_	_	_
36	bound	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	P	_	NOUN	_	Number=Sing	_	_	_	_
40	sequence	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	specificity	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	AT	_	NOUN	_	Number=Sing	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	similar	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	P	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	only	_	ADV	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	small	_	ADJ	_	Degree=Pos	_	_	_	_
24	amount	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	P65	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	P	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	crude	_	ADJ	_	Degree=Pos	_	_	_	_
36	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
37	extracts	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	component	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	s	_	X	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	AT	_	PROPN	_	_	_	_	_	_
14	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	potential	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	reconstitute	_	VERB	_	VerbForm=Inf	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	P	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	whereas	_	SCONJ	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	PROPN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	alone	_	ADV	_	_	_	_	_	_
29	can	_	AUX	_	VerbForm=Fin	_	_	_	_
30	not	_	PART	_	_	_	_	_	_
31	account	_	VERB	_	VerbForm=Inf	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	P	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	crude	_	ADJ	_	Degree=Pos	_	_	_	_
39	extracts	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Unlike	_	ADP	_	_	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	AT	_	ADP	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	P	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	contain	_	VERB	_	VerbForm=Inf	_	_	_	_
13	AP1	_	NOUN	_	Number=Sing	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	component	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012342	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	early	_	ADJ	_	Degree=Pos	_	_	_	_
4	growth	_	NOUN	_	Number=Sing	_	_	_	_
5	response	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	pp90rsk	_	NOUN	_	Number=Sing	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	work	_	NOUN	_	Number=Sing	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
7	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	early	_	ADJ	_	Degree=Pos	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	EGR	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	during	_	ADP	_	_	_	_	_	_
23	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	U	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	SYM	_	_	_	_	_	_
28	937	_	NUM	_	NumType=Card	_	_	_	_
29	myeloid	_	ADJ	_	Number=Sing	_	_	_	_
30	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Differentiation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	U	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	SYM	_	_	_	_	_	_
5	937	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	13	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	acetate	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	TPA	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	activator	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	serine	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	threonine	_	NOUN	_	Number=Sing	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	kinase	_	NOUN	_	Number=Sing	_	_	_	_
26	C	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	EGR	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	promoter	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	reporter	_	NOUN	_	Number=Sing	_	_	_	_
40	constructs	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	EGR	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	six	_	NUM	_	NumType=Card	_	_	_	_
8	CC	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	A/T	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	6GG	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	CArG	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	motifs	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	5'-	_	NUM	_	Number=Plur	_	_	_	_
4	most	_	ADV	_	_	_	_	_	_
5	distal	_	ADJ	_	Degree=Pos	_	_	_	_
6	CArG	_	NOUN	_	Number=Sing	_	_	_	_
7	sequences	_	NOUN	_	Number=Plur	_	_	_	_
8	conferred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	TPA	_	NOUN	_	Number=Sing	_	_	_	_
10	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	there	_	PRON	_	_	_	_	_	_
5	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	little	_	ADJ	_	Degree=Pos	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	TPA	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	EGR	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	TPA	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	resistant	_	ADJ	_	Number=Sing	_	_	_	_
20	U	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	937	_	NUM	_	NumType=Card	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	variant	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	TUR	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	both	_	CCONJ	_	_	_	_	_	_
4	U-937	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	TUR	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
10	acid	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	serine	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	threonine	_	NOUN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	2A	_	NUM	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	induction	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
30	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	EGR	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	through	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	5'-	_	NUM	_	_	_	_	_	_
39	most	_	ADJ	_	Degree=Sup	_	_	_	_
40	CArG	_	ADJ	_	Number=Sing	_	_	_	_
41	element	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	findings	_	NOUN	_	Number=Plur	_	_	_	_
4	supported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	involvement	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	serine	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	threonine	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	EGR	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
23	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	40S	_	NOUN	_	Number=Plur	_	_	_	_
28	ribosomal	_	ADJ	_	Number=Sing	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	S6	_	PROPN	_	Number=Sing	_	_	_	_
31	serine	_	NOUN	_	Number=Sing	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	threonine	_	NOUN	_	Number=Sing	_	_	_	_
34	kinases	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	pp70S6K	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	pp90rsk	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	both	_	DET	_	_	_	_	_	_
3	kinases	_	NOUN	_	Number=Plur	_	_	_	_
4	participate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	in	_	SCONJ	_	_	_	_	_	_
6	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	growth	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	there	_	PRON	_	_	_	_	_	_
11	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	no	_	DET	_	_	_	_	_	_
13	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	pp70S6K	_	NOUN	_	Number=Sing	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	TPA	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
22	acid	_	ADJ	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
26	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	pp70S6K	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	no	_	DET	_	_	_	_	_	_
13	effect	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	EGR	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	pp90rsk	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	peptide	_	NOUN	_	Number=Sing	_	_	_	_
13	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	S6	_	PROPN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	kinase	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	TPA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	U-937	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	not	_	ADV	_	_	_	_	_	_
30	TUR	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Okadaic	_	ADJ	_	Number=Sing	_	_	_	_
2	acid	_	NOUN	_	Number=Sing	_	_	_	_
3	treatment	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	both	_	DET	_	_	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	types	_	NOUN	_	Number=Plur	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	pp90rsk	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012356	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
3	virus	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	Tat	_	PROPN	_	Number=Sing	_	_	_	_
7	upregulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	secretion	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Dysregulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
4	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	play	_	VERB	_	VerbForm=Inf	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	important	_	ADJ	_	Degree=Pos	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	Tat	_	NOUN	_	Number=Sing	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	_	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
29	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	chloramphenicol	_	NOUN	_	Number=Sing	_	_	_	_
36	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
37	constructs	_	NOUN	_	Number=Plur	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	secreting	_	VERB	_	VerbForm=Ger	_	_	_	_
44	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
45	T	_	PROPN	_	Number=Sing	_	_	_	_
46	cells	_	NOUN	_	Number=Plur	_	_	_	_
47	as	_	ADP	_	_	_	_	_	_
48	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
49	model	_	NOUN	_	Number=Sing	_	_	_	_
50	system	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HIV	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_

1	Tat	_	PROPN	_	Number=Sing	_	_	_	_
2	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	five	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	eightfold	_	NOUN	_	VerbForm=Inf	_	_	_	_
8	increase	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
24	myristate	_	NOUN	_	Number=Sing	_	_	_	_
25	acetate	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	secretion	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	more	_	ADJ	_	Degree=Cmp	_	_	_	_
8	than	_	ADP	_	_	_	_	_	_
9	twofold	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	primary	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
22	HIV	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	Tat	_	NOUN	_	Number=Sing	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
4	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	Tat	_	PROPN	_	Number=Sing	_	_	_	_
7	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
9	effect	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	primarily	_	ADV	_	_	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	level	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	at	_	ADP	_	_	_	_	_	_
8	positions	_	NOUN	_	Number=Plur	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	206	_	NUM	_	NumType=Card	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	-	_	SYM	_	_	_	_	_	_
13	195	_	NUM	_	NumType=Card	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	not	_	ADV	_	_	_	_	_	_
24	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	Tat	_	NOUN	_	Number=Sing	_	_	_	_
28	effect	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Tat	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	increase	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	could	_	AUX	_	VerbForm=Fin	_	_	_	_
13	selectively	_	ADV	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	antisense	_	NOUN	_	Degree=Pos	_	_	_	_
18	tat	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	unlike	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	analogous	_	ADJ	_	Degree=Pos	_	_	_	_
24	effect	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
28	lymphotropic	_	ADJ	_	Degree=Pos	_	_	_	_
29	virus	_	NOUN	_	Number=Sing	_	_	_	_
30	type	_	NOUN	_	Number=Sing	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	Tax	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
36	A	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	increase	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	might	_	AUX	_	VerbForm=Fin	_	_	_	_
10	facilitate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	virus	_	NOUN	_	Number=Sing	_	_	_	_
12	spread	_	VERB	_	Number=Sing	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	might	_	AUX	_	VerbForm=Fin	_	_	_	_
5	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	hypergammaglobulinemia	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	together	_	ADV	_	_	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	other	_	ADJ	_	Degree=Pos	_	_	_	_
14	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
15	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	dysregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	T-helper	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	dysfunctions	_	NOUN	_	Number=Plur	_	_	_	_
24	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
27	patients	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012358	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Pyrrolidine	_	PROPN	_	Number=Sing	_	_	_	_
2	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	potent	_	ADJ	_	Degree=Pos	_	_	_	_
6	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	NF	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	prevents	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
26	HL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	60	_	NUM	_	NumType=Card	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	pyrrolidine	_	NOUN	_	Number=Sing	_	_	_	_
7	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	potently	_	ADV	_	_	_	_	_	_
14	blocks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	induction	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	variety	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	agents	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
6	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	line	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	HL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	60	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	10	_	NUM	_	NumType=Card	_	_	_	_
16	micrograms	_	NOUN	_	Number=Plur	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	mL	_	NOUN	_	Number=Sing	_	_	_	_
19	etoposide	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	microM	_	NOUN	_	Number=Sing	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	beta	_	NOUN	_	Number=Sing	_	_	_	_
26	-D	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	arabinofuranosylcytosine	_	NOUN	_	Number=Sing	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	within	_	ADP	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	hr	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	subsequently	_	ADV	_	_	_	_	_	_
40	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
42	within	_	ADP	_	_	_	_	_	_
43	3	_	NUM	_	NumType=Card	_	_	_	_
44	-	_	SYM	_	_	_	_	_	_
45	4	_	NUM	_	NumType=Card	_	_	_	_
46	hr	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	simultaneous	_	ADJ	_	Degree=Pos	_	_	_	_
3	addition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	50	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	SYM	_	_	_	_	_	_
7	500	_	NUM	_	NumType=Card	_	_	_	_
8	microM	_	NUM	_	Number=Sing	_	_	_	_
9	PDTC	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	agents	_	NOUN	_	Number=Plur	_	_	_	_
13	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	completely	_	ADV	_	_	_	_	_	_
21	abrogated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	morphologically	_	ADV	_	_	_	_	_	_
24	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
25	changes	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	internucleosomal	_	ADJ	_	Degree=Pos	_	_	_	_
28	DNA	_	NOUN	_	Number=Sing	_	_	_	_
29	fragmentation	_	NOUN	_	Number=Sing	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	up	_	ADP	_	_	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	6	_	NUM	_	NumType=Card	_	_	_	_
34	hr	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
4	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	endonuclease	_	NOUN	_	Degree=Pos	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	whole	_	ADJ	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	lysates	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	etoposide	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	concentration	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	10	_	NUM	_	NumType=Card	_	_	_	_
27	microM	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	PDTC	_	PROPN	_	Number=Sing	_	_	_	_
3	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	metal	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	ion	_	ADJ	_	Number=Sing	_	_	_	_
10	chelating	_	NOUN	_	Number=Sing	_	_	_	_
11	activities	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	effects	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	N-acetyl	_	PROPN	_	Number=Sing	_	_	_	_
19	-L	_	PUNCT	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	NAC	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	o-phenanthroline	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	OP	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	metal	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	ion	_	NOUN	_	Number=Sing	_	_	_	_
37	chelator	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	on	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	induction	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	60	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	100	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	500	_	NUM	_	NumType=Card	_	_	_	_
13	microM	_	NOUN	_	Number=Sing	_	_	_	_
14	OP	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	hr	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	not	_	ADV	_	_	_	_	_	_
21	10	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	SYM	_	_	_	_	_	_
23	60	_	NUM	_	NumType=Card	_	_	_	_
24	mM	_	NUM	_	NumType=Card	_	_	_	_
25	NAC	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
29	occurrence	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
32	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	etoposide	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	PROPN	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	important	_	ADJ	_	Degree=Pos	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
19	process	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012360	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	development	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	functionally	_	ADV	_	_	_	_	_	_
5	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	work	_	NOUN	_	Number=Sing	_	_	_	_
3	reviewed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	article	_	NOUN	_	Number=Sing	_	_	_	_
7	separates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	development	_	NOUN	_	Number=Sing	_	_	_	_
11	into	_	ADP	_	_	_	_	_	_
12	four	_	NUM	_	NumType=Card	_	_	_	_
13	phases	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	First	_	ADV	_	_	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	expansion	_	NOUN	_	Number=Sing	_	_	_	_
5	phase	_	NOUN	_	Number=Sing	_	_	_	_
6	prior	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	TCR	_	NOUN	_	Number=Sing	_	_	_	_
9	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	programming	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	at	_	ADV	_	_	_	_	_	_
20	least	_	ADV	_	Degree=Sup	_	_	_	_
21	some	_	DET	_	_	_	_	_	_
22	response	_	NOUN	_	Number=Sing	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	phase	_	NOUN	_	Number=Sing	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	some	_	DET	_	_	_	_	_	_
7	extent	_	NOUN	_	Number=Sing	_	_	_	_
8	outside	_	ADP	_	_	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	thymus	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	profound	_	ADJ	_	Degree=Pos	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	deficit	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	nude	_	ADJ	_	Degree=Pos	_	_	_	_
10	mice	_	NOUN	_	Number=Plur	_	_	_	_
11	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	thymus	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	far	_	ADV	_	Degree=Pos	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	most	_	ADV	_	_	_	_	_	_
20	potent	_	ADJ	_	Degree=Pos	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	for	_	SCONJ	_	_	_	_	_	_
23	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	expansion	_	NOUN	_	Number=Sing	_	_	_	_
26	per	_	ADP	_	_	_	_	_	_
27	se	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	even	_	ADV	_	_	_	_	_	_
30	if	_	SCONJ	_	_	_	_	_	_
31	other	_	ADJ	_	Degree=Pos	_	_	_	_
32	sites	_	NOUN	_	Number=Plur	_	_	_	_
33	can	_	AUX	_	VerbForm=Fin	_	_	_	_
34	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
35	some	_	DET	_	_	_	_	_	_
36	response	_	NOUN	_	Number=Sing	_	_	_	_
37	acquisition	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Second	_	ADV	_	_	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	phase	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	TCR	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	details	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	selects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	particular	_	ADJ	_	Degree=Pos	_	_	_	_
10	loci	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	still	_	ADV	_	_	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	TCR	_	NOUN	_	Number=Sing	_	_	_	_
9	gamma	_	NOUN	_	Number=Sing	_	_	_	_
10	loci	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	gamma	_	NOUN	_	Number=Sing	_	_	_	_
14	delta	_	NOUN	_	Number=Sing	_	_	_	_
15	lineage	_	NOUN	_	Number=Sing	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	always	_	ADV	_	_	_	_	_	_
19	take	_	VERB	_	VerbForm=Inf	_	_	_	_
20	place	_	NOUN	_	Number=Sing	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
24	stage	_	NOUN	_	Number=Sing	_	_	_	_
25	strictly	_	ADV	_	_	_	_	_	_
26	equivalent	_	ADJ	_	Degree=Pos	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	TCR	_	NOUN	_	Number=Sing	_	_	_	_
32	beta	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	alpha	_	NOUN	_	Number=Sing	_	_	_	_
36	beta	_	NOUN	_	Number=Sing	_	_	_	_
37	lineage	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
41	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	not	_	PART	_	_	_	_	_	_
43	clear	_	ADJ	_	Degree=Pos	_	_	_	_
44	just	_	ADV	_	_	_	_	_	_
45	how	_	ADV	_	PronType=Int	_	_	_	_
46	early	_	ADV	_	Degree=Pos	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	two	_	NUM	_	NumType=Card	_	_	_	_
49	lineages	_	NOUN	_	Number=Plur	_	_	_	_
50	diverge	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	TCR	_	NOUN	_	Number=Sing	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	lineage	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	however	_	ADV	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	final	_	ADJ	_	Degree=Pos	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	rearrangement	_	NOUN	_	Number=Sing	_	_	_	_
14	events	_	NOUN	_	Number=Plur	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
19	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	interruption	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
25	response	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	loss	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	conventional	_	ADJ	_	Degree=Pos	_	_	_	_
5	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	probably	_	ADV	_	_	_	_	_	_
8	caused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	alterations	_	NOUN	_	Number=Plur	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	level	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	signaling	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	may	_	AUX	_	VerbForm=Fin	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	manifestation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
25	state	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	precondition	_	NOUN	_	Number=Sing	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	selection	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Third	_	ADV	_	_	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	complex	_	ADJ	_	Degree=Pos	_	_	_	_
5	process	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	selection	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Whereas	_	SCONJ	_	_	_	_	_	_
2	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	can	_	AUX	_	VerbForm=Fin	_	_	_	_
6	undergo	_	VERB	_	VerbForm=Inf	_	_	_	_
7	forms	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	positive	_	ADJ	_	Degree=Pos	_	_	_	_
10	selection	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	antigen	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
17	expansion	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	negative	_	ADJ	_	Degree=Pos	_	_	_	_
21	selection	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	abortive	_	ADJ	_	Degree=Pos	_	_	_	_
25	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
26	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	anergy	_	NOUN	_	Number=Sing	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	death	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	neither	_	CCONJ	_	_	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	exactly	_	ADV	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	same	_	ADJ	_	Degree=Pos	_	_	_	_
38	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
39	that	_	PRON	_	PronType=Rel	_	_	_	_
40	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
44	cortex	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Negative	_	ADJ	_	Degree=Pos	_	_	_	_
2	selection	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cortex	_	NOUN	_	Number=Sing	_	_	_	_
6	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	suicidal	_	ADJ	_	Degree=Pos	_	_	_	_
11	inversion	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	antigen	_	ADJ	_	Number=Sing	_	_	_	_
14	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	instead	_	ADV	_	_	_	_	_	_
17	of	_	SCONJ	_	_	_	_	_	_
18	turning	_	VERB	_	VerbForm=Ger	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	destroys	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
30	own	_	ADJ	_	Degree=Pos	_	_	_	_
31	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	genes	_	NOUN	_	Number=Plur	_	_	_	_
3	that	_	PRON	_	PronType=Rel	_	_	_	_
4	need	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	yet	_	ADV	_	_	_	_	_	_
14	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	but	_	CCONJ	_	_	_	_	_	_
17	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	unquestionably	_	ADV	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	form	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	interesting	_	ADJ	_	Degree=Pos	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	humans	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	rats	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	cortical	_	ADJ	_	Degree=Pos	_	_	_	_
11	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	undergoing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	negative	_	ADJ	_	Degree=Pos	_	_	_	_
14	selection	_	NOUN	_	Number=Sing	_	_	_	_
15	can	_	AUX	_	VerbForm=Fin	_	_	_	_
16	still	_	ADV	_	_	_	_	_	_
17	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2R	_	PROPN	_	NumType=Card	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	even	_	ADV	_	_	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	rescued	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	vitro	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	if	_	SCONJ	_	_	_	_	_	_
31	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	provided	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Perhaps	_	ADV	_	_	_	_	_	_
2	murine	_	VERB	_	Number=Sing	_	_	_	_
3	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	denied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	form	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	rescue	_	NOUN	_	Number=Sing	_	_	_	_
10	because	_	SCONJ	_	_	_	_	_	_
11	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
12	shut	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	off	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2R	_	NUM	_	NumType=Card	_	_	_	_
17	beta	_	NOUN	_	Number=Sing	_	_	_	_
18	chain	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	earlier	_	ADJ	_	Degree=Cmp	_	_	_	_
23	stage	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	because	_	SCONJ	_	_	_	_	_	_
26	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
27	may	_	AUX	_	VerbForm=Fin	_	_	_	_
28	be	_	AUX	_	VerbForm=Inf	_	_	_	_
29	uncommonly	_	ADV	_	_	_	_	_	_
30	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	cf.	_	PROPN	_	Number=Sing	_	_	_	_
36	Sentman	_	PROPN	_	Number=Sing	_	_	_	_
37	et	_	X	_	_	_	_	_	_
38	al	_	X	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_

1	1991	_	NUM	_	NumType=Card	_	_	_	_
2	;	_	PUNCT	_	_	_	_	_	_
3	Strasser	_	PROPN	_	Number=Sing	_	_	_	_
4	et	_	X	_	_	_	_	_	_
5	al	_	PROPN	_	Number=Sing	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	1991	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Even	_	ADV	_	_	_	_	_	_
2	so	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	medullary	_	ADJ	_	Degree=Pos	_	_	_	_
5	thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	at	_	ADV	_	_	_	_	_	_
8	least	_	ADV	_	Degree=Sup	_	_	_	_
9	partially	_	ADV	_	_	_	_	_	_
10	susceptible	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	negative	_	ADJ	_	Degree=Pos	_	_	_	_
13	selection	_	NOUN	_	Number=Sing	_	_	_	_
14	even	_	ADV	_	_	_	_	_	_
15	as	_	SCONJ	_	_	_	_	_	_
16	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
17	continue	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	mature	_	VERB	_	VerbForm=Inf	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012361	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	LPS	_	NOUN	_	Number=Sing	_	_	_	_
2	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
7	:	_	PUNCT	_	_	_	_	_	_
8	three	_	NUM	_	NumType=Card	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	'	_	PUNCT	_	_	_	_	_	_
11	cytosins	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	DNA	_	PROPN	_	Number=Sing	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	motif	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	detection	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	upregulated	_	ADJ	_	Degree=Pos	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	p50	_	NOUN	_	Number=Sing	_	_	_	_
28	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	LPS	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	repeatedly	_	ADV	_	_	_	_	_	_
11	then	_	ADV	_	PronType=Dem	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	initially	_	ADV	_	_	_	_	_	_
14	high	_	ADJ	_	Degree=Pos	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	TNF	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	tumor	_	NOUN	_	Number=Sing	_	_	_	_
21	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	only	_	ADV	_	_	_	_	_	_
27	very	_	ADV	_	_	_	_	_	_
28	low	_	ADJ	_	Degree=Pos	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	i.e.	_	X	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	LPS	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	still	_	ADV	_	_	_	_	_	_
4	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	CD14	_	PROPN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	still	_	ADV	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	mobilize	_	VERB	_	VerbForm=Inf	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	into	_	ADP	_	_	_	_	_	_
21	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	binding	_	VERB	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	employing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	605	_	NUM	_	NumType=Card	_	_	_	_
10	motif	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	TNF	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	GGGGCTGTCCC	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	line	_	NOUN	_	Number=Sing	_	_	_	_
30	Mono	_	PROPN	_	Number=Sing	_	_	_	_
31	Mac	_	PROPN	_	Number=Sing	_	_	_	_
32	6	_	NUM	_	NumType=Card	_	_	_	_
33	there	_	PRON	_	_	_	_	_	_
34	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	predominance	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	p50p50	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappa	_	NOUN	_	Number=Sing	_	_	_	_
43	B	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	now	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	mutant	_	ADJ	_	Number=Sing	_	_	_	_
7	motif	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	exchanges	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	terminal	_	NOUN	_	Number=Sing	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	'	_	PUNCT	_	_	_	_	_	_
14	C	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	G	_	NOUN	_	Number=Sing	_	_	_	_
18	fails	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	p50	_	NOUN	_	Number=Sing	_	_	_	_
23	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	upregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	LPS	_	NOUN	_	Number=Sing	_	_	_	_
29	toler	_	NOUN	_	Number=Sing	_	_	_	_
30	ant	_	CCONJ	_	_	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	Mono	_	PROPN	_	Number=Sing	_	_	_	_
33	Mac	_	PROPN	_	Number=Sing	_	_	_	_
34	6	_	NUM	_	NumType=Card	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	same	_	ADJ	_	Degree=Pos	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	true	_	ADJ	_	Degree=Pos	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	extracts	_	NOUN	_	Number=Plur	_	_	_	_
8	taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	murine	_	NOUN	_	Number=Sing	_	_	_	_
12	P388D1	_	NOUN	_	Number=Sing	_	_	_	_
13	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	line	_	NOUN	_	Number=Sing	_	_	_	_
16	when	_	ADV	_	PronType=Int	_	_	_	_
17	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	-	_	SYM	_	_	_	_	_	_
21	516	_	NUM	_	NumType=Card	_	_	_	_
22	motif	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	murine	_	NOUN	_	Number=Sing	_	_	_	_
26	TNF	_	NOUN	_	Number=Sing	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	GGGGGCTTTCCC	_	PROPN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	wild	_	NOUN	_	Number=Sing	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	motif	_	NOUN	_	Number=Sing	_	_	_	_
6	gives	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	p50p50	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	again	_	ADV	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	upregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	whereas	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	mutant	_	NOUN	_	Number=Sing	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	3	_	NUM	_	NumType=Card	_	_	_	_
24	'	_	NOUN	_	_	_	_	_	_
25	G	_	NOUN	_	Number=Sing	_	_	_	_
26	shows	_	NOUN	_	Number=Plur	_	_	_	_
27	hardly	_	ADV	_	_	_	_	_	_
28	any	_	DET	_	_	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	p50p50	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Conversely	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	murine	_	NOUN	_	Number=Sing	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	light	_	NOUN	_	Number=Sing	_	_	_	_
7	chain	_	NOUN	_	Number=Sing	_	_	_	_
8	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
9	motif	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	GGGGACTTTCCG	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	efficiently	_	ADV	_	_	_	_	_	_
16	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	p50p50	_	NOUN	_	Number=Sing	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
22	murine	_	NOUN	_	Number=Sing	_	_	_	_
23	P388	_	NUM	_	Number=Sing	_	_	_	_
24	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	however	_	ADV	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	readily	_	ADV	_	_	_	_	_	_
7	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	when	_	ADV	_	PronType=Int	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	3'	_	NOUN	_	Number=Sing	_	_	_	_
11	G	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	replaced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	C.	_	NOUN	_	Number=Sing	_	_	_	_
17	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
18	data	_	NOUN	_	Number=Sing	_	_	_	_
19	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	detection	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	upregulated	_	ADJ	_	Degree=Pos	_	_	_	_
25	p50	_	NUM	_	Number=Sing	_	_	_	_
26	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	LPS	_	NOUN	_	Number=Sing	_	_	_	_
29	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
33	on	_	ADP	_	_	_	_	_	_
34	subtle	_	ADJ	_	Degree=Pos	_	_	_	_
35	differences	_	NOUN	_	Number=Plur	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	sequence	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	DNA	_	PROPN	_	Number=Sing	_	_	_	_
42	binding	_	VERB	_	Number=Sing	_	_	_	_
43	motif	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012364	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	disposition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	sulphamethoxazole	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
7	metabolites	_	NOUN	_	Number=Plur	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	implications	_	NOUN	_	Number=Plur	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	hypersensitivity	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	1	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	Bioactivation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	sulphamethoxazole	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	SMX	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	chemically	_	ADV	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
13	metabolites	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	conjugation	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	involved	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	SMX	_	PROPN	_	Number=Sing	_	_	_	_
25	hypersensitivity	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	therefore	_	ADV	_	_	_	_	_	_
4	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	metabolism	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	disposition	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	conjugation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	SMX	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	metabolites	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	vitro	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	2	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	Flow	_	ADJ	_	Number=Sing	_	_	_	_
4	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
5	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	N	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	hydroxy	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	SMX	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	NHOH	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	nitroso	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	SMX	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	NO	_	INTJ	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	metabolites	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	SMX	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	but	_	CCONJ	_	_	_	_	_	_
28	not	_	ADV	_	_	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	SMX	_	NOUN	_	Number=Sing	_	_	_	_
31	itself	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs|Reflex=Yes	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	surface	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	viable	_	ADJ	_	Degree=Pos	_	_	_	_
38	white	_	ADJ	_	Degree=Pos	_	_	_	_
39	blood	_	NOUN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Cellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	haptenation	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	SMX	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	NO	_	DET	_	_	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
11	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	GSH	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	3	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	SMX	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	NHOH	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	SMX	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	NO	_	DET	_	_	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	rapidly	_	ADV	_	_	_	_	_	_
12	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	back	_	ADV	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	parent	_	NOUN	_	Number=Sing	_	_	_	_
17	compound	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	CYS	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	GSH	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
28	blood	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	plasma	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
34	that	_	SCONJ	_	_	_	_	_	_
35	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
36	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	important	_	ADJ	_	Degree=Pos	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
41	bioinactivation	_	NOUN	_	Number=Sing	_	_	_	_
42	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	4	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	Fluorescence	_	PROPN	_	Number=Sing	_	_	_	_
4	HPLC	_	PROPN	_	Number=Sing	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	SMX	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	NHOH	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	SMX	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	NO	_	DET	_	_	_	_	_	_
14	depleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	CYS	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	GSH	_	PROPN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	buffer	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	lesser	_	ADJ	_	Degree=Cmp	_	_	_	_
25	extent	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	plasma	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	5	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	Neutrophil	_	ADJ	_	Number=Sing	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	neutrophil	_	NOUN	_	Degree=Pos	_	_	_	_
9	function	_	NOUN	_	Number=Sing	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
14	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	SMX	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	NHOH	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	SMX	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	NO	_	INTJ	_	_	_	_	_	_
23	than	_	ADP	_	_	_	_	_	_
24	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
25	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	loss	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	membrane	_	NOUN	_	Number=Sing	_	_	_	_
29	viability	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	with	_	SCONJ	_	_	_	_	_	_
32	SMX	_	PROPN	_	Number=Sing	_	_	_	_
33	having	_	VERB	_	VerbForm=Ger	_	_	_	_
34	no	_	DET	_	_	_	_	_	_
35	effect	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	significantly	_	ADV	_	_	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	P<0.05	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	more	_	ADV	_	_	_	_	_	_
8	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	direct	_	ADJ	_	Degree=Pos	_	_	_	_
12	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
13	effects	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	SMX	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	NO	_	INTJ	_	_	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	6	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	Partitioning	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	SMX	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	NHOH	_	PROPN	_	Number=Sing	_	_	_	_
8	into	_	ADP	_	_	_	_	_	_
9	red	_	ADJ	_	Degree=Pos	_	_	_	_
10	blood	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	significantly	_	ADV	_	_	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	P<0.05	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	hydroxylamine	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	dapsone	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	7	_	X	_	_	_	_	_	_
2	.	_	PUNCT	_	_	_	_	_	_
3	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	balance	_	NOUN	_	Number=Sing	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	oxidation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	SMX	_	PROPN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	toxic	_	ADJ	_	Degree=Pos	_	_	_	_
16	metabolites	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	reduction	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	important	_	ADJ	_	Degree=Pos	_	_	_	_
23	protective	_	ADJ	_	Degree=Pos	_	_	_	_
24	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
25	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	If	_	SCONJ	_	_	_	_	_	_
2	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	imbalance	_	NOUN	_	Number=Sing	_	_	_	_
4	exists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	haptenation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	toxic	_	ADJ	_	Degree=Pos	_	_	_	_
10	metabolites	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	bodily	_	VERB	_	Degree=Pos	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	including	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	surface	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	viable	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	can	_	AUX	_	VerbForm=Fin	_	_	_	_
21	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	may	_	AUX	_	VerbForm=Fin	_	_	_	_
25	result	_	VERB	_	VerbForm=Inf	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	drug	_	NOUN	_	Number=Sing	_	_	_	_
28	hypersensitivity	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012370	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Mn	_	PROPN	_	Number=Sing	_	_	_	_
4	SOD	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	without	_	ADP	_	_	_	_	_	_
9	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	mutant	_	ADJ	_	Number=Sing	_	_	_	_
15	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Endotoxin	_	PROPN	_	Number=Sing	_	_	_	_
2	selectively	_	ADV	_	_	_	_	_	_
3	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	monocyte	_	NOUN	_	Number=Sing	_	_	_	_

1	Mn	_	X	_	Number=Sing	_	_	_	_
2	superoxide	_	NOUN	_	Number=Sing	_	_	_	_
3	dismutase	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	SOD	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	without	_	SCONJ	_	_	_	_	_	_
8	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Cu	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	Zn	_	NOUN	_	Number=Sing	_	_	_	_
14	SOD	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	catalase	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
20	peroxidase	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	little	_	ADV	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	about	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	structure	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	relationship	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
18	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	Mn	_	NOUN	_	Number=Sing	_	_	_	_
20	SOD	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	mutant	_	ADJ	_	Number=Sing	_	_	_	_
9	Escherichia	_	PROPN	_	Number=Sing	_	_	_	_
10	coli	_	NOUN	_	Number=Sing	_	_	_	_
11	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
12	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
13	myristoyl	_	NOUN	_	Degree=Pos	_	_	_	_
14	fatty	_	NOUN	_	Number=Sing	_	_	_	_
15	acid	_	NOUN	_	Number=Sing	_	_	_	_
16	at	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	3	_	NUM	_	NumType=Card	_	_	_	_
19	'	_	PUNCT	_	_	_	_	_	_
20	R-3-	_	PUNCT	_	_	_	_	_	_
21	hydroxymyristate	_	ADJ	_	Degree=Pos	_	_	_	_
22	position	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	lipid	_	NOUN	_	Number=Sing	_	_	_	_
26	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	moiety	_	NOUN	_	Number=Sing	_	_	_	_
28	retained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
30	full	_	ADJ	_	Degree=Pos	_	_	_	_
31	capacity	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	coagulate	_	VERB	_	VerbForm=Inf	_	_	_	_
34	Limulus	_	PROPN	_	Number=Sing	_	_	_	_
35	amoebocyte	_	NOUN	_	Number=Sing	_	_	_	_
36	lysate	_	NOUN	_	Number=Sing	_	_	_	_
37	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	wild	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	type	_	NOUN	_	Number=Sing	_	_	_	_
43	E.	_	PROPN	_	Number=Sing	_	_	_	_
44	coli	_	NOUN	_	Number=Sing	_	_	_	_
45	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	markedly	_	ADV	_	_	_	_	_	_
48	stimulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	activation	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	human	_	ADJ	_	Degree=Pos	_	_	_	_
53	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
54	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
55	factor	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
58	and	_	CCONJ	_	_	_	_	_	_
59	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
60	induction	_	NOUN	_	Number=Sing	_	_	_	_
61	of	_	ADP	_	_	_	_	_	_
62	Mn	_	PROPN	_	Number=Sing	_	_	_	_
63	SOD	_	NOUN	_	Number=Sing	_	_	_	_
64	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
65	and	_	CCONJ	_	_	_	_	_	_
66	enzyme	_	NOUN	_	Degree=Pos	_	_	_	_
67	activity	_	NOUN	_	Number=Sing	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	contrast	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	wild	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
13	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
16	significant	_	ADJ	_	Degree=Pos	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	tumor	_	NOUN	_	Number=Sing	_	_	_	_
20	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
26	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
40	translocation	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	protein	_	NOUN	_	Number=Sing	_	_	_	_
46	kinase	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	1	_	X	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	lipid	_	VERB	_	VerbForm=Inf	_	_	_	_
8	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	myristoyl	_	PROPN	_	Degree=Pos	_	_	_	_
10	fatty	_	NOUN	_	Number=Sing	_	_	_	_
11	acid	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	although	_	SCONJ	_	_	_	_	_	_
14	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	important	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	induction	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	not	_	PART	_	_	_	_	_	_
30	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	induction	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	Mn	_	PROPN	_	Number=Sing	_	_	_	_
36	SOD	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	_	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	mediated	_	VERB	_	Degree=Pos	_	_	_	_
43	induction	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	Mn	_	NOUN	_	Number=Sing	_	_	_	_
46	SOD	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
49	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
50	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
51	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	at	_	ADV	_	_	_	_	_	_
54	least	_	ADV	_	Degree=Sup	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	part	_	ADJ	_	Degree=Pos	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	through	_	ADP	_	_	_	_	_	_
59	different	_	ADJ	_	Degree=Pos	_	_	_	_
60	signal	_	NOUN	_	Number=Sing	_	_	_	_
61	transduction	_	NOUN	_	Number=Sing	_	_	_	_
62	pathways	_	NOUN	_	Number=Plur	_	_	_	_
63	,	_	PUNCT	_	_	_	_	_	_
64	and	_	CCONJ	_	_	_	_	_	_
65	3	_	NUM	_	_	_	_	_	_
66	)	_	PUNCT	_	_	_	_	_	_
67	failure	_	NOUN	_	Number=Sing	_	_	_	_
68	of	_	ADP	_	_	_	_	_	_
69	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
70	mutant	_	ADJ	_	Number=Sing	_	_	_	_
71	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
72	to	_	PART	_	_	_	_	_	_
73	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
74	tumor	_	NOUN	_	Number=Sing	_	_	_	_
75	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
76	factor	_	NOUN	_	Number=Sing	_	_	_	_
77	-	_	PUNCT	_	_	_	_	_	_
78	alpha	_	NOUN	_	Number=Sing	_	_	_	_
79	production	_	NOUN	_	Number=Sing	_	_	_	_
80	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
81	,	_	PUNCT	_	_	_	_	_	_
82	at	_	ADV	_	_	_	_	_	_
83	least	_	ADV	_	Degree=Sup	_	_	_	_
84	in	_	ADP	_	_	_	_	_	_
85	part	_	ADJ	_	Number=Sing	_	_	_	_
86	,	_	PUNCT	_	_	_	_	_	_
87	due	_	ADP	_	_	_	_	_	_
88	to	_	ADP	_	_	_	_	_	_
89	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
90	inability	_	NOUN	_	Number=Sing	_	_	_	_
91	to	_	PART	_	_	_	_	_	_
92	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
93	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
94	-	_	PUNCT	_	_	_	_	_	_
95	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
96	protein	_	NOUN	_	Number=Sing	_	_	_	_
97	kinase	_	NOUN	_	Number=Sing	_	_	_	_
98	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012371	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Of	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	GATA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	proteins	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	only	_	ADV	_	_	_	_	_	_
9	GATA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	selectively	_	ADV	_	_	_	_	_	_
13	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	5	_	NUM	_	NumType=Card	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	5	_	NUM	_	NumType=Card	_	_	_	_
25	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
30	GATA	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	proteins	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-5	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	support	_	VERB	_	VerbForm=Inf	_	_	_	_
16	B	_	DET	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	growth	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	eosinophilic	_	ADJ	_	Degree=Pos	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	ATL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	16T	_	NUM	_	NumType=Card	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	5	_	NUM	_	NumType=Card	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	region	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	within	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	5	_	NUM	_	NumType=Card	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	that	_	PRON	_	PronType=Rel	_	_	_	_
29	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	5	_	NUM	_	NumType=Card	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	cis	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	acting	_	VERB	_	Number=Sing	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	core	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	motif	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	A/T	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	GATA	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	A	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	G	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	GATA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
26	family	_	NOUN	_	Number=Sing	_	_	_	_
27	proteins	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	thus	_	ADV	_	_	_	_	_	_
30	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	involvement	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
35	family	_	NOUN	_	Number=Sing	_	_	_	_
36	members	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cloning	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	GATA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	hGATA	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	4	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	show	_	VERB	_	VerbForm=Inf	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	hGATA	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	selectively	_	ADV	_	_	_	_	_	_
26	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	70	_	NUM	_	NumType=Card	_	_	_	_
31	GATA	_	NOUN	_	Number=Sing	_	_	_	_
32	site	_	NOUN	_	Number=Sing	_	_	_	_
33	within	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	5	_	NUM	_	NumType=Card	_	_	_	_
38	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
39	promoter	_	NOUN	_	Number=Sing	_	_	_	_
40	region	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	promoter	_	NOUN	_	Number=Sing	_	_	_	_
3	deletion	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	mutation	_	NOUN	_	Number=Sing	_	_	_	_
6	analyses	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	established	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	positive	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	both	_	CCONJ	_	_	_	_	_	_
6	hGATA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	PMA	_	PROPN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	A23187	_	NOUN	_	Number=Sing	_	_	_	_
13	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	5	_	NUM	_	NumType=Card	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	requirement	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	another	_	DET	_	_	_	_	_	_
5	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	element	_	NOUN	_	Number=Sing	_	_	_	_
7	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	CLE0	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	which	_	PRON	_	PronType=Rel	_	_	_	_
11	lies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	downstream	_	ADV	_	_	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	70	_	NUM	_	NumType=Card	_	_	_	_
17	GATA	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	also	_	ADV	_	_	_	_	_	_
22	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	ATL	_	DET	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	16T	_	NUM	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	express	_	VERB	_	Degree=Pos	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	three	_	NUM	_	NumType=Card	_	_	_	_
9	GATA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	hGATA	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	hGATA	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	hGATA	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	each	_	DET	_	_	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
30	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	potential	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	consensus	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	A/T	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	GATA	_	PROPN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	G	_	NOUN	_	Number=Sing	_	_	_	_
44	/	_	PUNCT	_	_	_	_	_	_
45	A	_	X	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	motif	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	using	_	VERB	_	VerbForm=Ger	_	_	_	_
4	ATL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	16T	_	NUM	_	NumType=Card	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	extract	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	GATA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	only	_	ADJ	_	Degree=Pos	_	_	_	_
19	GATA	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	DET	_	PronType=Rel	_	_	_	_
24	forms	_	VERB	_	Number=Plur	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	DNA	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	complex	_	NOUN	_	Number=Sing	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	70	_	NUM	_	NumType=Card	_	_	_	_
34	GATA	_	NOUN	_	Number=Sing	_	_	_	_
35	site	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assay	_	VERB	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	extracts	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	COS	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	GATA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	binding	_	VERB	_	Number=Sing	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	GATA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	4	_	NUM	_	NumType=Card	_	_	_	_
21	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	highest	_	ADJ	_	Degree=Sup	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	affinity	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	70	_	NUM	_	NumType=Card	_	_	_	_
30	GATA	_	NOUN	_	Number=Sing	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	among	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	three	_	NUM	_	NumType=Card	_	_	_	_
35	GATA	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	binding	_	NOUN	_	Number=Sing	_	_	_	_
38	proteins	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
4	ability	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	among	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	three	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	GATA	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	highest	_	ADJ	_	Degree=Sup	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	selective	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	GATA	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	5	_	NUM	_	NumType=Card	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	circumstance	_	NOUN	_	Number=Sing	_	_	_	_
24	where	_	ADV	_	PronType=Rel	_	_	_	_
25	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
26	members	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	GATA	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	binding	_	NOUN	_	Number=Sing	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012376	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	anthracycline	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	erythroleukemic	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Aclacinomycin	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	ACLA	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	doxorubicin	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	DOX	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	subtoxic	_	ADJ	_	Degree=Pos	_	_	_	_
14	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
17	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	line	_	NOUN	_	Number=Sing	_	_	_	_
25	K562	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	hemoglobinization	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
12	gamma	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	globin	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	porphobilinogen	_	NOUN	_	Number=Sing	_	_	_	_
17	deaminase	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	PBGD	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	heme	_	NOUN	_	Number=Sing	_	_	_	_
26	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	run	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	assays	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	ACLA	_	PROPN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	including	_	VERB	_	VerbForm=Ger	_	_	_	_
23	gamma	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	globin	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	PBGD	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
30	receptor	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	GATA	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	transcription	_	NOUN	_	Number=Sing	_	_	_	_
37	factor	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	DOX	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	rate	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	unchanged	_	VERB	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	comparison	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	control	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
7	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	actinomycin	_	NOUN	_	Number=Sing	_	_	_	_
10	D	_	PROPN	_	Number=Sing	_	_	_	_
11	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	DOX	_	PROPN	_	Number=Sing	_	_	_	_
14	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	stability	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	PBGD	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	GATA	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	whereas	_	SCONJ	_	_	_	_	_	_
27	ACLA	_	PROPN	_	Number=Sing	_	_	_	_
28	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	not	_	PART	_	_	_	_	_	_
30	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	half	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	lives	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
37	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	increase	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	steady	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	state	_	NOUN	_	Number=Sing	_	_	_	_
10	level	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	anthracycline	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
22	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	ACLA	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
33	stabilization	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	DOX	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
41	on	_	ADP	_	_	_	_	_	_
42	de	_	X	_	Number=Sing	_	_	_	_
43	novo	_	X	_	Number=Sing	_	_	_	_
44	protein	_	NOUN	_	Number=Sing	_	_	_	_
45	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	GATA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	level	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	ACLA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	not	_	ADV	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	DOX	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	anthracyclines	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	although	_	SCONJ	_	_	_	_	_	_
6	closely	_	ADV	_	_	_	_	_	_
7	related	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	structures	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	act	_	VERB	_	VerbForm=Inf	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	inducers	_	NOUN	_	Number=Plur	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
20	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Indeed	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	transcriptionally	_	ADV	_	_	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	ACLA	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	mainly	_	ADV	_	_	_	_	_	_
16	posttranscriptionally	_	ADV	_	_	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	DOX	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012381	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	specific	_	ADJ	_	Degree=Pos	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	megakaryoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
9	disorders	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Currently	_	ADV	_	_	_	_	_	_
2	available	_	ADJ	_	Degree=Pos	_	_	_	_
3	data	_	NOUN	_	Number=Sing	_	_	_	_
4	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
10	pathways	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	closely	_	ADV	_	_	_	_	_	_
13	related	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	each	_	DET	_	_	_	_	_	_
16	other	_	ADJ	_	Degree=Pos	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	there	_	PRON	_	_	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	exist	_	VERB	_	VerbForm=Inf	_	_	_	_
22	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	common	_	ADJ	_	Degree=Pos	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
27	two	_	NUM	_	NumType=Card	_	_	_	_
28	lineages	_	NOUN	_	Number=Plur	_	_	_	_
29	may	_	AUX	_	VerbForm=Fin	_	_	_	_
30	exist	_	VERB	_	VerbForm=Inf	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Acute	_	ADJ	_	Degree=Pos	_	_	_	_
2	megakaryoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	AML	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	M7	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	transient	_	ADJ	_	Degree=Pos	_	_	_	_
11	myeloproliferative	_	ADJ	_	Degree=Pos	_	_	_	_
12	disorder	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	Down	_	PROPN	_	Number=Sing	_	_	_	_
15	's	_	PART	_	_	_	_	_	_
16	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	TMD	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
24	growth	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
27	blast	_	ADJ	_	Degree=Pos	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
32	markers	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	blast	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	lineage	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factors	_	NOUN	_	Number=Plur	_	_	_	_
10	such	_	ADJ	_	Degree=Pos	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	GATA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	common	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
18	lineages	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	frequently	_	ADV	_	_	_	_	_	_
21	express	_	ADJ	_	Degree=Pos	_	_	_	_
22	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	mRNAs	_	NOUN	_	Number=Plur	_	_	_	_
26	such	_	ADJ	_	Degree=Pos	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	gamma	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	globin	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
33	delta	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	aminolevulinate	_	ADJ	_	Degree=Pos	_	_	_	_
36	synthase	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	ALAS	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	E	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
44	that	_	SCONJ	_	_	_	_	_	_
45	most	_	ADJ	_	Degree=Sup	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	blasts	_	NOUN	_	Number=Plur	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	M7	_	PROPN	_	Number=Sing	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	TMD	_	NOUN	_	Number=Sing	_	_	_	_
53	cases	_	NOUN	_	Number=Plur	_	_	_	_
54	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
55	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
58	phenotypes	_	NOUN	_	Number=Plur	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	blasts	_	VERB	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	M7	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	TMD	_	NOUN	_	Number=Sing	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	correspond	_	VERB	_	VerbForm=Inf	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	lineages	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012383	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Replication	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	autocrine	_	ADJ	_	Degree=Pos	_	_	_	_
18	secretion	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	tumor	_	NOUN	_	Number=Sing	_	_	_	_
21	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	through	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	control	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	TNF	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	controls	_	VERB	_	Number=Sing	_	_	_	_
10	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	major	_	ADJ	_	Degree=Pos	_	_	_	_
16	inducer	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
20	virus	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	replication	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	chronically	_	ADV	_	_	_	_	_	_
29	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	cultures	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	by	_	SCONJ	_	_	_	_	_	_
19	using	_	VERB	_	VerbForm=Ger	_	_	_	_
20	neutralizing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	anti-TNF	_	ADJ	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	TNF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	alpha	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Primary	_	ADJ	_	Degree=Pos	_	_	_	_
2	resting	_	NOUN	_	Number=Sing	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	supported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	replication	_	NOUN	_	Number=Sing	_	_	_	_
11	after	_	ADP	_	_	_	_	_	_
12	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Addition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	neutralizing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	anti-TNF	_	ADJ	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
8	drastically	_	ADV	_	_	_	_	_	_
9	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	p24	_	NUM	_	Number=Sing	_	_	_	_
11	antigen	_	NOUN	_	Number=Sing	_	_	_	_
12	release	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	prevented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	CD4	_	NOUN	_	Number=Sing	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	depletion	_	NOUN	_	Number=Sing	_	_	_	_
19	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	infection	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Anti-TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	alpha	_	NOUN	_	Number=Sing	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	prevented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	NF	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	good	_	ADJ	_	Degree=Pos	_	_	_	_
22	correlation	_	NOUN	_	Number=Sing	_	_	_	_
23	between	_	ADP	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	HIV	_	NOUN	_	Number=Sing	_	_	_	_
30	replication	_	NOUN	_	Number=Sing	_	_	_	_
31	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
32	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	supplementing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cultures	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	high	_	ADJ	_	Degree=Pos	_	_	_	_
8	doses	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	reverted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	anti-TNF	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	HIV	_	NOUN	_	Number=Sing	_	_	_	_
29	p24	_	NUM	_	Number=Sing	_	_	_	_
30	antigen	_	NOUN	_	Number=Sing	_	_	_	_
31	release	_	NOUN	_	Number=Sing	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	same	_	ADJ	_	Degree=Pos	_	_	_	_
41	cultures	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	anti-TNF	_	ADJ	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	alpha	_	PROPN	_	Number=Sing	_	_	_	_
6	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	HIV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	long	_	ADJ	_	Degree=Pos	_	_	_	_
11	terminal	_	NOUN	_	Number=Sing	_	_	_	_
12	repeat	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	LTR	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	reporter	_	NOUN	_	Number=Sing	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	primary	_	ADJ	_	Degree=Pos	_	_	_	_
25	T	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	response	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	either	_	CCONJ	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	presence	_	NOUN	_	Number=Sing	_	_	_	_
36	or	_	CCONJ	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	absence	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	HIV	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	Tat	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	autocrine	_	ADJ	_	Number=Sing	_	_	_	_
9	TNF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	secretion	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	SCONJ	_	_	_	_	_	_
14	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	replication	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	primary	_	ADJ	_	Degree=Pos	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	because	_	ADP	_	_	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	ability	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	maintain	_	VERB	_	VerbForm=Inf	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	T	_	PROPN	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012384	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	tumor	_	NOUN	_	Number=Sing	_	_	_	_
10	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
17	cloning	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	sequencing	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	characterization	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
25	assignment	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Lipopolysaccharide	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	LPS	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	potent	_	ADJ	_	Degree=Pos	_	_	_	_
8	stimulator	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	causing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	secretion	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	tumor	_	NOUN	_	Number=Sing	_	_	_	_
18	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	TNF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	other	_	ADJ	_	Degree=Pos	_	_	_	_
28	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
29	mediators	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Given	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	deleterious	_	ADJ	_	Degree=Pos	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	host	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	TNF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	postulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	TNF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	must	_	AUX	_	VerbForm=Fin	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	tightly	_	ADV	_	_	_	_	_	_
26	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nature	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	s	_	X	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	control	_	VERB	_	Number=Sing	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	humans	_	NOUN	_	Number=Plur	_	_	_	_
19	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	obscure	_	ADJ	_	Degree=Pos	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	although	_	SCONJ	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
26	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
28	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	previous	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	pertaining	_	VERB	_	VerbForm=Ger	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	macrophage	_	VERB	_	Number=Sing	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	LPS	_	NOUN	_	Number=Sing	_	_	_	_
10	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	novel	_	NOUN	_	Number=Sing	_	_	_	_
13	DNA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	domain	_	NOUN	_	Number=Sing	_	_	_	_
17	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	-	_	SYM	_	_	_	_	_	_
20	550	_	NUM	_	NumType=Card	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	-	_	SYM	_	_	_	_	_	_
23	487	_	NUM	_	NumType=Card	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	TNF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	that	_	PRON	_	PronType=Rel	_	_	_	_
32	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
34	activity	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	but	_	CCONJ	_	_	_	_	_	_
37	lacks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	any	_	DET	_	_	_	_	_	_
39	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	binding	_	NOUN	_	Number=Sing	_	_	_	_
45	sites	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	DNA	_	PROPN	_	Number=Sing	_	_	_	_
6	fragment	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	isolate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	purify	_	VERB	_	VerbForm=Inf	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	60	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kDa	_	NOUN	_	Number=Sing	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	fragment	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	obtained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	amino	_	ADJ	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	terminal	_	NOUN	_	Number=Sing	_	_	_	_
26	sequence	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	design	_	VERB	_	VerbForm=Inf	_	_	_	_
33	degenerate	_	ADJ	_	Degree=Pos	_	_	_	_
34	probes	_	NOUN	_	Number=Plur	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	screen	_	VERB	_	VerbForm=Inf	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
39	library	_	NOUN	_	Number=Sing	_	_	_	_
40	from	_	ADP	_	_	_	_	_	_
41	THP	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	1	_	NUM	_	NumType=Card	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
4	clone	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	1.8	_	NUM	_	NumType=Card	_	_	_	_
7	kb	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	isolated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	fully	_	ADV	_	_	_	_	_	_
13	sequenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
5	clone	_	NOUN	_	Number=Sing	_	_	_	_
6	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	LPS	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	THP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	;	_	PUNCT	_	_	_	_	_	_
21	hence	_	ADV	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	name	_	NOUN	_	Number=Sing	_	_	_	_
25	LPS	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	TNF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	LITAF	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	LITAF	_	ADJ	_	Degree=Pos	_	_	_	_
4	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	THP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	reduction	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	TNF	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	high	_	ADJ	_	Degree=Pos	_	_	_	_
5	level	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	LITAF	_	ADJ	_	Degree=Pos	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	predominantly	_	ADV	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	placenta	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
19	blood	_	NOUN	_	Number=Sing	_	_	_	_
20	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	lymph	_	NOUN	_	Number=Sing	_	_	_	_
23	nodes	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	spleen	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
4	localization	_	NOUN	_	Number=Sing	_	_	_	_
5	using	_	VERB	_	VerbForm=Ger	_	_	_	_
6	fluorescence	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	situ	_	NOUN	_	Number=Sing	_	_	_	_
9	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
10	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	LITAF	_	PROPN	_	Number=Sing	_	_	_	_
13	mapped	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	chromosome	_	VERB	_	Number=Sing	_	_	_	_
16	16p12	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	16p13.3	_	NUM	_	NumType=Card	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	findings	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	LITAF	_	PROPN	_	Number=Sing	_	_	_	_
8	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	TNF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	proposes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	new	_	ADJ	_	Degree=Pos	_	_	_	_
26	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	control	_	VERB	_	VerbForm=Inf	_	_	_	_
29	TNF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	alpha	_	NOUN	_	Number=Sing	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012388	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	BCL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	6	_	NUM	_	NumType=Card	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	POZ	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	zinc	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	finger	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	sequence	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
19	repressor	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Approximately	_	ADV	_	_	_	_	_	_
2	40	_	NUM	_	NumType=Card	_	_	_	_
3	%	_	SYM	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	diffuse	_	ADJ	_	Degree=Pos	_	_	_	_
6	large	_	ADJ	_	Degree=Pos	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
13	translocations	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	deregulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	SCONJ	_	_	_	_	_	_
23	juxtaposing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
25	promoters	_	NOUN	_	Number=Plur	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	BCL	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	6	_	NUM	_	NumType=Card	_	_	_	_
31	coding	_	NOUN	_	Number=Sing	_	_	_	_
32	domain	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	95	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kDa	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	six	_	NUM	_	NumType=Card	_	_	_	_
12	C	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	terminal	_	NOUN	_	Number=Sing	_	_	_	_
15	zinc	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	finger	_	NOUN	_	Number=Sing	_	_	_	_
18	motifs	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	N	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	terminal	_	NOUN	_	Number=Sing	_	_	_	_
24	POZ	_	NOUN	_	Number=Sing	_	_	_	_
25	domain	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
30	may	_	AUX	_	VerbForm=Fin	_	_	_	_
31	function	_	VERB	_	VerbForm=Inf	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
9	ability	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
12	recombinant	_	ADJ	_	Number=Sing	_	_	_	_
13	BCL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	vitro	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	here	_	ADV	_	PronType=Dem	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	BCL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	6	_	NUM	_	NumType=Card	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	present	_	ADJ	_	Degree=Pos	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	DNA	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	binding	_	VERB	_	Number=Sing	_	_	_	_
32	complexes	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
35	extracts	_	NOUN	_	Number=Plur	_	_	_	_
36	from	_	ADP	_	_	_	_	_	_
37	various	_	ADJ	_	Degree=Pos	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	lines	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	transient	_	ADJ	_	Degree=Pos	_	_	_	_
3	transfectin	_	NOUN	_	Number=Sing	_	_	_	_
4	experiments	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	repress	_	VERB	_	VerbForm=Inf	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	promoters	_	NOUN	_	Number=Plur	_	_	_	_
12	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	DNA	_	PROPN	_	Number=Sing	_	_	_	_
16	target	_	NOUN	_	Number=Sing	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	upon	_	ADP	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	DNA	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	presence	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	intact	_	NOUN	_	Degree=Pos	_	_	_	_
34	N	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
37	half	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	protein	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	part	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
9	molecule	_	NOUN	_	Number=Sing	_	_	_	_
10	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	autonomous	_	ADJ	_	Degree=Pos	_	_	_	_
13	transrepressor	_	NOUN	_	Number=Sing	_	_	_	_
14	domain	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	that	_	DET	_	_	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	noncontiguous	_	ADJ	_	Degree=Pos	_	_	_	_
19	regions	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	including	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	POZ	_	NOUN	_	Number=Sing	_	_	_	_
24	motif	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	mediate	_	ADJ	_	Degree=Pos	_	_	_	_
27	maximum	_	ADJ	_	Degree=Pos	_	_	_	_
28	transrepressive	_	ADJ	_	Degree=Pos	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	BCL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	6	_	NUM	_	NumType=Card	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	function	_	VERB	_	VerbForm=Inf	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	repressor	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	implications	_	NOUN	_	Number=Plur	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	role	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	BCL6	_	PROPN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	normal	_	ADJ	_	Degree=Pos	_	_	_	_
29	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
30	development	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	lymphomagenesis	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012390	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	c	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	fos	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	during	_	ADP	_	_	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	cycle	_	NOUN	_	Number=Sing	_	_	_	_
18	progression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	HL60	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	products	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	c-fos	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	p62c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	fos	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	p39c	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	jun	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	members	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	AP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	family	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	play	_	VERB	_	VerbForm=Inf	_	_	_	_
35	important	_	ADJ	_	Degree=Pos	_	_	_	_
36	roles	_	NOUN	_	Number=Plur	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	regulation	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	gene	_	NOUN	_	Number=Sing	_	_	_	_
42	expression	_	NOUN	_	Number=Sing	_	_	_	_
43	during	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	cell	_	NOUN	_	Number=Sing	_	_	_	_
46	cycle	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Most	_	ADJ	_	Degree=Sup	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	relation	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	cycle	_	NOUN	_	Number=Sing	_	_	_	_
15	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
21	level	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	therefore	_	ADV	_	_	_	_	_	_
25	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	give	_	VERB	_	VerbForm=Inf	_	_	_	_
28	direct	_	ADJ	_	Degree=Pos	_	_	_	_
29	information	_	NOUN	_	Number=Sing	_	_	_	_
30	about	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	presence	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	proteins	_	NOUN	_	Number=Plur	_	_	_	_
36	during	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	cycle	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	Western	_	ADJ	_	Degree=Pos	_	_	_	_
5	blotting	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	presence	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	during	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	cycles	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	two	_	NUM	_	NumType=Card	_	_	_	_
19	different	_	ADJ	_	Degree=Pos	_	_	_	_
20	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
21	systems	_	NOUN	_	Number=Plur	_	_	_	_
22	:	_	PUNCT	_	_	_	_	_	_

1	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	continuously	_	ADV	_	_	_	_	_	_
3	growing	_	VERB	_	VerbForm=Ger	_	_	_	_
4	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
5	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	line	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	HL60	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	normal	_	ADJ	_	Degree=Pos	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	into	_	ADP	_	_	_	_	_	_
16	cycle	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	phyto	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	hemagglutinin	_	PROPN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	PHA	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	normal	_	ADJ	_	Degree=Pos	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
29	blood	_	NOUN	_	Number=Sing	_	_	_	_
30	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	PBL	_	NOUN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	AP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	consists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	dimers	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	Fos	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	Jun	_	PROPN	_	Number=Sing	_	_	_	_
19	family	_	NOUN	_	Number=Sing	_	_	_	_
20	proteins	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	also	_	ADV	_	_	_	_	_	_
24	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	using	_	VERB	_	VerbForm=Ger	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	gel	_	NOUN	_	Number=Sing	_	_	_	_
28	shift	_	NOUN	_	Number=Sing	_	_	_	_
29	assay	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	p62c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	fos	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	p39c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	jun	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	throughout	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	cycle	_	NOUN	_	Number=Sing	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	HL60	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	PHA	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	PBL	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
35	postulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	that	_	SCONJ	_	_	_	_	_	_
37	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
38	proteins	_	NOUN	_	Number=Plur	_	_	_	_
39	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	throughout	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	cell	_	NOUN	_	Number=Sing	_	_	_	_
44	cycle	_	NOUN	_	Number=Sing	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	not	_	PART	_	_	_	_	_	_
47	transiently	_	ADV	_	_	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	G0	_	NOUN	_	Number=Sing	_	_	_	_
51	to	_	ADP	_	_	_	_	_	_
52	G1	_	PROPN	_	Number=Sing	_	_	_	_
53	transition	_	NOUN	_	Number=Sing	_	_	_	_
54	as	_	SCONJ	_	_	_	_	_	_
55	previous	_	ADJ	_	Degree=Pos	_	_	_	_
56	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
57	studies	_	NOUN	_	Number=Plur	_	_	_	_
58	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
59	indicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	uncoupling	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	AP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	p62c	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	fos	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	p39c	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	jun	_	NOUN	_	Number=Sing	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	more	_	ADV	_	_	_	_	_	_
27	strongly	_	ADV	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	G1	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	G2/M	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	phase	_	NOUN	_	Number=Sing	_	_	_	_
36	enriched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	samples	_	NOUN	_	Number=Plur	_	_	_	_
38	than	_	ADP	_	_	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	S	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	phase	_	NOUN	_	Number=Sing	_	_	_	_
44	enriched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	samples	_	NOUN	_	Number=Plur	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	HL60	_	NOUN	_	Number=Sing	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	while	_	SCONJ	_	_	_	_	_	_
51	levels	_	NOUN	_	Number=Plur	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
54	p62c	_	NOUN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	fos	_	NOUN	_	Number=Sing	_	_	_	_
57	and	_	CCONJ	_	_	_	_	_	_
58	p39c	_	NOUN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	jun	_	NOUN	_	Number=Sing	_	_	_	_
61	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
62	constant	_	ADJ	_	Degree=Pos	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	Nuclei	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
4	PBL	_	NOUN	_	Number=Sing	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	different	_	ADJ	_	Degree=Pos	_	_	_	_
7	donors	_	NOUN	_	Number=Plur	_	_	_	_
8	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	p62c	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	fos	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	p39c	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	jun	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	AP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	majority	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	samples	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Following	_	VERB	_	VerbForm=Ger	_	_	_	_
2	PHA	_	PROPN	_	Number=Sing	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	PBL	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	increase	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	delayed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	respect	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	augmentation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	p39c	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	jun	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
6	p62c	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	fos	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	p39c	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	jun	_	NOUN	_	Number=Sing	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	present	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	HL60	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	PHA	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	PBL	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
5	p62c	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	fos	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
12	PBL	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	although	_	SCONJ	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	some	_	DET	_	_	_	_	_	_
17	cases	_	NOUN	_	Number=Plur	_	_	_	_
18	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
19	p39c	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	jun	_	NOUN	_	Number=Sing	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	subcellular	_	ADJ	_	Degree=Pos	_	_	_	_
28	compartmentalization	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
31	proteinsmay	_	NOUN	_	Number=Plur	_	_	_	_
32	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
33	under	_	ADP	_	_	_	_	_	_
34	certain	_	ADJ	_	Degree=Pos	_	_	_	_
35	circumstances	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012393	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	signaling	_	VERB	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	mitogen	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	kinase	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
15	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
16	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	HePTP	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
7	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	counterbalance	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
17	kinases	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
22	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	many	_	ADJ	_	Degree=Pos	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	which	_	PRON	_	PronType=Int	_	_	_	_
27	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	high	_	ADJ	_	Degree=Pos	_	_	_	_
30	degree	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	substrate	_	ADJ	_	Degree=Pos	_	_	_	_
33	specificity	_	NOUN	_	Number=Sing	_	_	_	_
34	because	_	ADP	_	_	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	physical	_	ADJ	_	Degree=Pos	_	_	_	_
37	association	_	NOUN	_	Number=Sing	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
40	targets	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	HePTP	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	results	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	suppression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	as	_	SCONJ	_	_	_	_	_	_
19	measured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	T	_	NUM	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	antigen	_	NOUN	_	Number=Sing	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factors	_	NOUN	_	Number=Plur	_	_	_	_
31	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	5	_	NUM	_	NumType=Card	_	_	_	_
35	'	_	PUNCT	_	_	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	gene	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Efforts	_	NOUN	_	Number=Plur	_	_	_	_
2	to	_	PART	_	_	_	_	_	_
3	pinpoint	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	exact	_	ADJ	_	Degree=Pos	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	action	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	specificity	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	HePTP	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	signaling	_	NOUN	_	Number=Sing	_	_	_	_
16	cascade	_	NOUN	_	Number=Sing	_	_	_	_
17	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	HePTP	_	PROPN	_	Number=Sing	_	_	_	_
20	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	directly	_	ADV	_	_	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	MAP	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	kinases	_	NOUN	_	Number=Plur	_	_	_	_
32	Erk1	_	PROPN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	2	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	consequently	_	ADV	_	_	_	_	_	_
37	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	duration	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
44	catalytic	_	ADJ	_	Degree=Pos	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	intact	_	NOUN	_	Number=Sing	_	_	_	_
48	T	_	NOUN	_	Number=Sing	_	_	_	_
49	cells	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	HePTP	_	PROPN	_	Number=Sing	_	_	_	_
5	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	no	_	DET	_	_	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	N	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	terminal	_	NOUN	_	Number=Sing	_	_	_	_
12	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	on	_	ADP	_	_	_	_	_	_
16	events	_	NOUN	_	Number=Plur	_	_	_	_
17	upstream	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	MAP	_	NOUN	_	Number=Sing	_	_	_	_
21	kinases	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	specificity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HePTP	_	PROPN	_	Number=Sing	_	_	_	_
5	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
8	physical	_	ADJ	_	Degree=Pos	_	_	_	_
9	association	_	NOUN	_	Number=Sing	_	_	_	_
10	through	_	ADP	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	noncatalytic	_	ADJ	_	Degree=Pos	_	_	_	_
13	N	_	NOUN	_	Number=Sing	_	_	_	_
14	terminus	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	Erk	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	another	_	DET	_	_	_	_	_	_
19	MAP	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	p38	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	not	_	ADV	_	_	_	_	_	_
26	Jnk	_	NOUN	_	Number=Sing	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	other	_	ADJ	_	Degree=Pos	_	_	_	_
29	proteins	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	HePTP	_	PROPN	_	Number=Sing	_	_	_	_
5	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	negative	_	ADJ	_	Degree=Pos	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	antigen	_	ADJ	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	signaling	_	VERB	_	Number=Sing	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	specifically	_	ADV	_	_	_	_	_	_
15	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	MAP	_	NOUN	_	Number=Sing	_	_	_	_
17	kinases	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	at	_	ADP	_	_	_	_	_	_
23	early	_	ADJ	_	Degree=Pos	_	_	_	_
24	time	_	NOUN	_	Number=Sing	_	_	_	_
25	points	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	T	_	NOUN	_	Number=Sing	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	before	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
38	dual	_	ADJ	_	Degree=Pos	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	specific	_	ADJ	_	Degree=Pos	_	_	_	_
41	MAP	_	NOUN	_	Number=Sing	_	_	_	_
42	kinase	_	NOUN	_	Number=Sing	_	_	_	_
43	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012394	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	through	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	inducer	_	NOUN	_	Number=Sing	_	_	_	_
10	molecule	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	CD69	_	PROPN	_	Number=Sing	_	_	_	_
13	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	AP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	AP	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	ascribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	early	_	ADJ	_	Degree=Pos	_	_	_	_
16	events	_	NOUN	_	Number=Plur	_	_	_	_
17	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	AP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
14	blood	_	NOUN	_	Number=Sing	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	inducer	_	NOUN	_	Number=Sing	_	_	_	_
22	molecule	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	AIM	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	CD69	_	PROPN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	pathway	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Phorbol	_	NOUN	_	Number=Sing	_	_	_	_
2	esters	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
7	AIM	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	CD69	_	PROPN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	surface	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	as	_	ADV	_	_	_	_	_	_
15	well	_	ADV	_	Degree=Pos	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	for	_	SCONJ	_	_	_	_	_	_
18	triggering	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	conjunction	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	anti-AIM	_	ADJ	_	Number=Sing	_	_	_	_
28	mAb	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Mobility	_	NOUN	_	Number=Sing	_	_	_	_
2	shift	_	NOUN	_	Number=Sing	_	_	_	_
3	assays	_	NOUN	_	Number=Plur	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	addition	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	anti-AIM	_	ADJ	_	Degree=Pos	_	_	_	_
9	mAb	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	PMA	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	markedly	_	ADV	_	_	_	_	_	_
17	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	AP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	cognate	_	NOUN	_	Number=Sing	_	_	_	_
28	sequence	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
32	ester	_	NOUN	_	Number=Sing	_	_	_	_
33	response	_	NOUN	_	Number=Sing	_	_	_	_
34	element	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	anti-AIM	_	ADJ	_	Number=Sing	_	_	_	_
5	mAb	_	NOUN	_	Number=Sing	_	_	_	_
6	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
9	any	_	DET	_	_	_	_	_	_
10	change	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	also	_	ADV	_	_	_	_	_	_
28	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	protein	_	NOUN	_	Number=Sing	_	_	_	_
31	kinase	_	NOUN	_	Number=Sing	_	_	_	_
32	C.	_	PROPN	_	Number=Sing	_	_	_	_
33	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	increase	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	AP	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	binding	_	NOUN	_	Number=Sing	_	_	_	_
41	activity	_	NOUN	_	Number=Sing	_	_	_	_
42	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
43	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	by	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	transcription	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	c	_	NOUN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	fos	_	NOUN	_	Number=Sing	_	_	_	_
55	but	_	CCONJ	_	_	_	_	_	_
56	not	_	ADV	_	_	_	_	_	_
57	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
58	of	_	ADP	_	_	_	_	_	_
59	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Blockade	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	complexes	_	NOUN	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	anti-Fos	_	NOUN	_	Number=Sing	_	_	_	_
11	mAb	_	PROPN	_	Number=Sing	_	_	_	_
12	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	direct	_	ADJ	_	Degree=Pos	_	_	_	_
15	participation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	c	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	Fos	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	AP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	complexes	_	NOUN	_	Number=Plur	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	anti-AIM	_	ADJ	_	Number=Sing	_	_	_	_
29	mAb	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Most	_	ADJ	_	Degree=Sup	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	could	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	eliminated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	when	_	ADV	_	PronType=Int	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	anti-AIM	_	NOUN	_	Number=Sing	_	_	_	_
14	mAb	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	added	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	culture	_	NOUN	_	Number=Sing	_	_	_	_
20	medium	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	presence	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	de	_	PROPN	_	Number=Sing	_	_	_	_
30	novo	_	PROPN	_	Number=Sing	_	_	_	_
31	protein	_	VERB	_	Number=Sing	_	_	_	_
32	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	induction	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	AP	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	binding	_	NOUN	_	Number=Sing	_	_	_	_
44	activity	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	evidence	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	DET	_	_	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
11	blood	_	NOUN	_	Number=Sing	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	through	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	AIM	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	pathway	_	NOUN	_	Number=Sing	_	_	_	_
19	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	AP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	SYM	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	pathway	_	NOUN	_	Number=Sing	_	_	_	_
5	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
9	step	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	initiation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	early	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	events	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012399	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	critical	_	ADJ	_	Degree=Pos	_	_	_	_
3	role	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Ets	_	NOUN	_	Number=Plur	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	related	_	ADJ	_	Degree=Pos	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	SCONJ	_	_	_	_	_	_
14	maintaining	_	VERB	_	VerbForm=Ger	_	_	_	_
15	CTL	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	mouse	_	NOUN	_	Number=Sing	_	_	_	_
22	perforin	_	NOUN	_	Degree=Pos	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	designed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	potential	_	ADJ	_	Degree=Pos	_	_	_	_
9	cis	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	elements	_	NOUN	_	Number=Plur	_	_	_	_
12	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	mouse	_	NOUN	_	Number=Sing	_	_	_	_
19	perforin	_	NOUN	_	Degree=Pos	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	DNase	_	NOUN	_	Number=Sing	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
4	site	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	DHS	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	mapping	_	NOUN	_	Number=Sing	_	_	_	_
9	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	perforin	_	NOUN	_	Number=Sing	_	_	_	_
13	locus	_	NOUN	_	Number=Sing	_	_	_	_
14	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	six	_	NUM	_	NumType=Card	_	_	_	_
16	DHS	_	NOUN	_	Number=Plur	_	_	_	_
17	within	_	ADP	_	_	_	_	_	_
18	7.0	_	NUM	_	NumType=Card	_	_	_	_
19	kb	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	5	_	NUM	_	NumType=Card	_	_	_	_
23	'	_	PUNCT	_	_	_	_	_	_
24	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
25	sequence	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	-	_	SYM	_	_	_	_	_	_
28	7.0	_	NUM	_	NumType=Card	_	_	_	_
29	kb	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	two	_	NUM	_	NumType=Card	_	_	_	_
33	DHS	_	NOUN	_	Number=Plur	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	intron	_	NOUN	_	Number=Sing	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	six	_	NUM	_	NumType=Card	_	_	_	_
3	5'	_	NUM	_	Number=Plur	_	_	_	_
4	upstream	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	one	_	NUM	_	NumType=Card	_	_	_	_
7	intronic	_	ADJ	_	Degree=Pos	_	_	_	_
8	DHS	_	NOUN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	only	_	ADV	_	_	_	_	_	_
13	perforin	_	NOUN	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Chloramphenicol	_	PROPN	_	Number=Sing	_	_	_	_
2	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	CAT	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	activities	_	NOUN	_	Number=Plur	_	_	_	_
7	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	5	_	NUM	_	NumType=Card	_	_	_	_
10	'	_	PUNCT	_	_	_	_	_	_
11	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	preferentially	_	ADV	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	perforin	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	lines	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	construct	_	NOUN	_	Number=Sing	_	_	_	_
3	termed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	PFP5a	_	NOUN	_	Number=Sing	_	_	_	_
5	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	795	_	NUM	_	NumType=Card	_	_	_	_
8	bp	_	PROPN	_	Number=Sing	_	_	_	_
9	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	highest	_	ADJ	_	Degree=Sup	_	_	_	_
12	CAT	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	PFP9a20	_	NOUN	_	Number=Sing	_	_	_	_
17	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	only	_	ADV	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	73	_	NUM	_	NumType=Card	_	_	_	_
21	bp	_	NOUN	_	Number=Sing	_	_	_	_
22	also	_	ADV	_	_	_	_	_	_
23	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	significantly	_	ADV	_	_	_	_	_	_
25	high	_	ADJ	_	Degree=Pos	_	_	_	_
26	CAT	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	CTLL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	R8	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	PFP9a20	_	PROPN	_	Number=Sing	_	_	_	_
6	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	potential	_	ADJ	_	Degree=Pos	_	_	_	_
9	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	sites	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	GC	_	NOUN	_	Number=Sing	_	_	_	_
14	box	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	GT	_	NOUN	_	Number=Sing	_	_	_	_
17	box	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	one	_	NUM	_	NumType=Card	_	_	_	_
21	Ets	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	EBS	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	each	_	DET	_	_	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cis	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	elements	_	NOUN	_	Number=Plur	_	_	_	_
13	bound	_	VERB	_	Degree=Pos	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	single	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	point	_	NOUN	_	Number=Sing	_	_	_	_
5	mutation	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	introduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	each	_	DET	_	_	_	_	_	_
10	GC	_	NOUN	_	Number=Sing	_	_	_	_
11	box	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	EBS	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	GT	_	NOUN	_	Number=Sing	_	_	_	_
17	box	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	PFP9a20	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	at	_	ADV	_	_	_	_	_	_
22	least	_	ADV	_	Degree=Sup	_	_	_	_
23	3	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
26	less	_	ADJ	_	Degree=Cmp	_	_	_	_
27	CAT	_	NOUN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	CTLL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	R8	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	confirm	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	importance	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	three	_	NUM	_	NumType=Card	_	_	_	_
8	cis	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	elements	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	perforin	_	NOUN	_	Degree=Pos	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	point	_	NOUN	_	Number=Sing	_	_	_	_
19	mutation	_	NOUN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	introduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	again	_	ADV	_	_	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	each	_	DET	_	_	_	_	_	_
25	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
26	GC	_	NOUN	_	Number=Sing	_	_	_	_
27	box	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	EBS	_	PROPN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	GT	_	NOUN	_	Number=Sing	_	_	_	_
33	box	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	PFP5a	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	point	_	NOUN	_	Number=Sing	_	_	_	_
3	mutations	_	NOUN	_	Number=Plur	_	_	_	_
4	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	2.5	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	fold	_	VERB	_	Number=Sing	_	_	_	_
13	reduction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	CAT	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	combination	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	three	_	NUM	_	NumType=Card	_	_	_	_
10	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
11	cis	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	acting	_	VERB	_	Number=Sing	_	_	_	_
14	elements	_	NOUN	_	Number=Plur	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	constitute	_	VERB	_	VerbForm=Inf	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
19	region	_	NOUN	_	Number=Sing	_	_	_	_
20	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	CTL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	perforin	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012400	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
2	acid	_	ADJ	_	Number=Sing	_	_	_	_
3	downmodulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	GATA1	_	ADJ	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	adult	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	progenitor	_	ADJ	_	Number=Sing	_	_	_	_
14	culture	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	trans	_	NOUN	_	Number=Plur	_	_	_	_
4	retinoic	_	PROPN	_	Number=Sing	_	_	_	_
5	acid	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	RA	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	important	_	ADJ	_	Degree=Pos	_	_	_	_
12	morphogen	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vertebrate	_	ADJ	_	Degree=Pos	_	_	_	_
15	development	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	constituent	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	adult	_	NOUN	_	Number=Sing	_	_	_	_
23	blood	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	also	_	ADV	_	_	_	_	_	_
27	involved	_	ADJ	_	Degree=Pos	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	control	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	growth	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	acute	_	ADJ	_	Degree=Pos	_	_	_	_
38	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
39	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	RA	_	PROPN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	normal	_	ADJ	_	Degree=Pos	_	_	_	_
10	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	SCONJ	_	_	_	_	_	_
12	using	_	VERB	_	VerbForm=Ger	_	_	_	_
13	early	_	ADJ	_	Degree=Pos	_	_	_	_
14	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
15	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	HPC	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	stringently	_	ADV	_	_	_	_	_	_
21	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	adult	_	NOUN	_	Number=Sing	_	_	_	_
24	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
25	blood	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	clonogenetic	_	ADJ	_	Degree=Pos	_	_	_	_
3	fetal	_	NOUN	_	Degree=Pos	_	_	_	_
4	calf	_	NOUN	_	Number=Sing	_	_	_	_
5	serum	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	supplemented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	FCS	_	NOUN	_	Number=Sing	_	_	_	_
10	+	_	SYM	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	nonsupplemented	_	ADJ	_	Degree=Pos	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	FCS	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	culture	_	NOUN	_	Number=Sing	_	_	_	_
20	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	saturating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	3	_	NUM	_	NumType=Card	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	3	_	NUM	_	NumType=Card	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
36	colony	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
39	factor	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	GM	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	CSF	_	PROPN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	Ep	_	NOUN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	(	_	PUNCT	_	_	_	_	_	_
51	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
52	with	_	ADP	_	_	_	_	_	_
53	c-kit	_	NOUN	_	Number=Sing	_	_	_	_
54	ligand	_	NOUN	_	Number=Sing	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	FCS	_	PROPN	_	Number=Sing	_	_	_	_
57	(	_	PUNCT	_	_	_	_	_	_
58	-)-	_	PUNCT	_	_	_	_	_	_
59	culture	_	NOUN	_	Number=Sing	_	_	_	_
60	conditions	_	NOUN	_	Number=Plur	_	_	_	_
61	)	_	PUNCT	_	_	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	RA	_	PROPN	_	Number=Sing	_	_	_	_
64	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
65	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
66	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
67	dose	_	NOUN	_	Number=Sing	_	_	_	_
68	-	_	PUNCT	_	_	_	_	_	_
69	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
70	shift	_	NOUN	_	Number=Sing	_	_	_	_
71	from	_	ADP	_	_	_	_	_	_
72	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
73	to	_	ADP	_	_	_	_	_	_
74	granulomonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
75	colony	_	NOUN	_	Number=Sing	_	_	_	_
76	formation	_	NOUN	_	Number=Sing	_	_	_	_
77	,	_	PUNCT	_	_	_	_	_	_
78	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
79	latter	_	ADJ	_	Degree=Pos	_	_	_	_
80	colonies	_	NOUN	_	Number=Plur	_	_	_	_
81	being	_	AUX	_	VerbForm=Ger	_	_	_	_
82	essentially	_	ADV	_	_	_	_	_	_
83	represented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
84	by	_	ADP	_	_	_	_	_	_
85	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
86	clones	_	NOUN	_	Number=Plur	_	_	_	_
87	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	shift	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	apparently	_	ADV	_	_	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	caused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
10	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	because	_	SCONJ	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	FCS	_	NOUN	_	Number=Sing	_	_	_	_
15	+	_	SYM	_	_	_	_	_	_

1	culture	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	total	_	ADJ	_	Degree=Pos	_	_	_	_
5	number	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	colonies	_	NOUN	_	Number=Plur	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	significantly	_	ADV	_	_	_	_	_	_
11	modified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	RA	_	PROPN	_	Number=Sing	_	_	_	_
14	addition	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	FCS	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	liquid-suspension	_	NOUN	_	Number=Sing	_	_	_	_
5	culture	_	NOUN	_	Number=Sing	_	_	_	_
6	supplemented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	saturating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	Ep	_	NOUN	_	Number=Sing	_	_	_	_
10	level	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	low	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dose	_	NOUN	_	Number=Sing	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	3/GM-CSF	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	adult	_	NOUN	_	Number=Sing	_	_	_	_
20	HPC	_	NOUN	_	Number=Sing	_	_	_	_
21	undergo	_	VERB	_	_	_	_	_	_
22	unilineage	_	NOUN	_	Number=Sing	_	_	_	_
23	erythropoietic	_	ADJ	_	Degree=Pos	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	:	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	again	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	high	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dose	_	NOUN	_	Number=Sing	_	_	_	_
9	RA	_	NOUN	_	Number=Sing	_	_	_	_
10	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	shift	_	NOUN	_	Number=Sing	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	pathway	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	RA	_	PROPN	_	Number=Sing	_	_	_	_
4	time	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	pulse	_	NOUN	_	Degree=Pos	_	_	_	_
9	treatment	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	semisolid	_	ADJ	_	Degree=Pos	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	liquid	_	ADJ	_	Degree=Pos	_	_	_	_
14	culture	_	NOUN	_	Number=Sing	_	_	_	_
15	show	_	VERB	_	Number=Sing	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	early	_	ADJ	_	Degree=Pos	_	_	_	_
18	RA	_	PROPN	_	Number=Sing	_	_	_	_
19	addition	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	most	_	ADV	_	_	_	_	_	_
22	effective	_	ADJ	_	Degree=Pos	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	thus	_	ADV	_	_	_	_	_	_
25	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
26	that	_	DET	_	_	_	_	_	_
27	early	_	ADJ	_	Degree=Pos	_	_	_	_
28	but	_	CCONJ	_	_	_	_	_	_
29	not	_	ADV	_	_	_	_	_	_
30	late	_	ADJ	_	Degree=Pos	_	_	_	_
31	HPC	_	PROPN	_	Number=Sing	_	_	_	_
32	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
36	action	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	then	_	ADV	_	PronType=Dem	_	_	_	_
3	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	master	_	NOUN	_	Number=Sing	_	_	_	_
9	GATA1	_	PROPN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	finger	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	normal	_	ADJ	_	Degree=Pos	_	_	_	_
21	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
22	development	_	NOUN	_	Number=Sing	_	_	_	_
23	;	_	PUNCT	_	_	_	_	_	_
24	addition	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	RA	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	HPC	_	NOUN	_	Number=Sing	_	_	_	_
29	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	into	_	ADP	_	_	_	_	_	_
31	unilineage	_	ADJ	_	Degree=Pos	_	_	_	_
32	erythropoietic	_	ADJ	_	Degree=Pos	_	_	_	_
33	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	liquid	_	ADJ	_	Degree=Pos	_	_	_	_
36	culture	_	NOUN	_	Number=Sing	_	_	_	_
37	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	virtually	_	ADV	_	_	_	_	_	_
40	complete	_	ADJ	_	Degree=Pos	_	_	_	_
41	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	GATA1	_	NOUN	_	Number=Sing	_	_	_	_
44	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
45	induction	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	RA	_	PROPN	_	Number=Sing	_	_	_	_
6	directly	_	ADV	_	_	_	_	_	_
7	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	program	_	NOUN	_	Number=Sing	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	level	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	early	_	ADJ	_	Degree=Pos	_	_	_	_
17	adult	_	NOUN	_	Number=Sing	_	_	_	_
18	HPC	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	may	_	AUX	_	VerbForm=Fin	_	_	_	_
22	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	shift	_	NOUN	_	Number=Sing	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
31	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
32	pathway	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	correlated	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	GATA1	_	NOUN	_	Number=Sing	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	early	_	ADJ	_	Degree=Pos	_	_	_	_
13	stages	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	erythropoietic	_	ADJ	_	Degree=Pos	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012410	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	STAT	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	related	_	ADJ	_	Degree=Pos	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	constitutively	_	ADV	_	_	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
11	blood	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	acute	_	ADJ	_	Degree=Pos	_	_	_	_
15	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
16	patients	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	signal	_	ADJ	_	Number=Sing	_	_	_	_
3	transduction	_	NOUN	_	Number=Sing	_	_	_	_
4	pathway	_	NOUN	_	Number=Sing	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	many	_	ADJ	_	Degree=Pos	_	_	_	_
8	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
9	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	recently	_	ADV	_	_	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	elaborated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	JAK	_	PROPN	_	Number=Sing	_	_	_	_
3	kinases	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	signal	_	NOUN	_	Number=Sing	_	_	_	_
7	transducers	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	activators	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	STAT	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
18	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	essential	_	ADJ	_	Degree=Pos	_	_	_	_
22	components	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	presence	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	constitutively	_	ADV	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	STAT	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
16	blood	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	patients	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	acute	_	ADJ	_	Degree=Pos	_	_	_	_
22	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
4	probes	_	NOUN	_	Number=Plur	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	-casein	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	IRF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	promoters	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	ISRE	_	PROPN	_	Number=Sing	_	_	_	_
18	probe	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	detect	_	VERB	_	VerbForm=Inf	_	_	_	_
21	STAT	_	NOUN	_	Number=Sing	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	extracts	_	NOUN	_	Number=Plur	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	acute	_	ADJ	_	Degree=Pos	_	_	_	_
28	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	bandshift	_	NOUN	_	Number=Sing	_	_	_	_
32	assays	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Specific	_	ADJ	_	Degree=Pos	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	complex	_	ADJ	_	Number=Sing	_	_	_	_
5	formation	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	probes	_	NOUN	_	Number=Plur	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	casein	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	IRF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	promoters	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	not	_	ADV	_	_	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	ISRE	_	PROPN	_	Number=Sing	_	_	_	_
28	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
29	probe	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	when	_	ADV	_	PronType=Int	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	extracts	_	NOUN	_	Number=Plur	_	_	_	_
34	from	_	ADP	_	_	_	_	_	_
35	acute	_	ADJ	_	Degree=Pos	_	_	_	_
36	lymphoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
37	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	ALL	_	DET	_	_	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	acute	_	ADJ	_	Degree=Pos	_	_	_	_
43	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
44	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	AML	_	NOUN	_	Number=Sing	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
49	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	nonradioactive	_	ADJ	_	Degree=Pos	_	_	_	_
4	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	competitors	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	show	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	specificity	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	complex	_	ADJ	_	Degree=Pos	_	_	_	_
14	formation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Specific	_	ADJ	_	Degree=Pos	_	_	_	_
2	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
3	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	against	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	individual	_	ADJ	_	Degree=Pos	_	_	_	_
7	STAT	_	NOUN	_	Number=Sing	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	supershift	_	NOUN	_	Number=Sing	_	_	_	_
13	experiments	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	related	_	ADJ	_	Degree=Pos	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	ALL	_	DET	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	related	_	ADJ	_	Degree=Pos	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	present	_	ADJ	_	Degree=Pos	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	extracts	_	NOUN	_	Number=Plur	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	AML	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	treated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
9	before	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	extracted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
20	factors	_	NOUN	_	Number=Plur	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	constitutively	_	ADV	_	_	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	vivo	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	likely	_	ADJ	_	Degree=Pos	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	STAT	_	PROPN	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	part	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	events	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	leukemogenesis	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012413	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	death	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	glucocorticoids	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	one	_	NUM	_	NumType=Card	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	earliest	_	ADJ	_	Degree=Sup	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	most	_	ADV	_	_	_	_	_	_
18	thoroughly	_	ADV	_	_	_	_	_	_
19	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	models	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	exact	_	ADJ	_	Degree=Pos	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
8	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
13	many	_	ADJ	_	Degree=Pos	_	_	_	_
14	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
17	changes	_	NOUN	_	Number=Plur	_	_	_	_
18	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
20	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	response	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
5	degradation	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	endonucleases	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
11	process	_	NOUN	_	Number=Sing	_	_	_	_
12	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	closely	_	ADV	_	_	_	_	_	_
15	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	as	_	ADV	_	_	_	_	_	_
18	well	_	ADV	_	Degree=Pos	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	involvement	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	several	_	ADJ	_	Degree=Pos	_	_	_	_
24	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	lysis	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
6	importance	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	treatment	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
17	neoplasms	_	NOUN	_	Number=Plur	_	_	_	_
18	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	recently	_	ADV	_	_	_	_	_	_
20	received	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	attention	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012420	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	degradation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	Fos	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	not	_	ADV	_	_	_	_	_	_
10	v-Fos	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	signal	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	c	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	Jun	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	proto	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
5	products	_	NOUN	_	Number=Plur	_	_	_	_
6	c-Fos	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	Jun	_	PROPN	_	Number=Sing	_	_	_	_
11	heterodimerize	_	NOUN	_	Number=Sing	_	_	_	_
12	through	_	ADP	_	_	_	_	_	_
13	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	leucine	_	NOUN	_	Number=Sing	_	_	_	_
15	zippers	_	NOUN	_	Number=Plur	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	form	_	VERB	_	VerbForm=Inf	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	AP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
3	activity	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
16	events	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	stability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	Fos	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	also	_	ADV	_	_	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	signal	_	NOUN	_	Number=Sing	_	_	_	_
16	transduction	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	transient	_	ADJ	_	Degree=Pos	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	vitro	_	ADJ	_	Number=Sing	_	_	_	_
7	degradation	_	NOUN	_	Number=Sing	_	_	_	_
8	experiments	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	stability	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	c	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	Fos	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	when	_	ADV	_	PronType=Int	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	dimerized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	phosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
25	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
6	ester	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	target	_	VERB	_	VerbForm=Inf	_	_	_	_
13	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	degradation	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	c-Fos	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	transiently	_	ADV	_	_	_	_	_	_
23	stabilized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	after	_	ADP	_	_	_	_	_	_
25	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	growth	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	v-Fos	_	NOUN	_	Number=Sing	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	retroviral	_	ADJ	_	Degree=Pos	_	_	_	_
6	counterpart	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	Fos	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	susceptible	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	degradation	_	NOUN	_	Number=Sing	_	_	_	_
17	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012427	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	antagonism	_	NOUN	_	Number=Sing	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
5	D3	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
8	acid	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	CD14	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	CD23	_	PROPN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	U	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	SYM	_	_	_	_	_	_
23	937	_	NUM	_	NumType=Card	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	1,25	_	NUM	_	NumType=Card	_	_	_	_
2	alpha-Dihydroxicholecalciferol	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	retinoic	_	PROPN	_	Degree=Pos	_	_	_	_
8	acid	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	RA	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	important	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulators	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	several	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	types	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	paper	_	NOUN	_	Number=Sing	_	_	_	_
3	describes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	how	_	ADV	_	PronType=Int	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
12	Ag	_	PROPN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	CD14	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	low	_	ADJ	_	Degree=Pos	_	_	_	_
19	affinity	_	NOUN	_	Number=Sing	_	_	_	_

1	Fc	_	PROPN	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	IgE	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	CD23	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	inversely	_	ADV	_	_	_	_	_	_
10	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	RA	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	U	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	937	_	NUM	_	NumType=Card	_	_	_	_
25	monoblasts	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	PMA	_	PROPN	_	Number=Sing	_	_	_	_
2	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	CD14	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	CD23	_	PROPN	_	Number=Sing	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Exposure	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	VitD3	_	PROPN	_	Number=Sing	_	_	_	_
4	rapidly	_	ADV	_	_	_	_	_	_
5	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	de	_	X	_	Number=Sing	_	_	_	_
8	novo	_	X	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	CD14	_	PROPN	_	Number=Sing	_	_	_	_
12	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
5	completely	_	ADV	_	_	_	_	_	_
6	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	CD14	_	PROPN	_	Number=Sing	_	_	_	_
12	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	ongoing	_	ADJ	_	Degree=Pos	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	CD14	_	PROPN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	VitD3	_	NOUN	_	Number=Sing	_	_	_	_
7	concomitantly	_	ADV	_	_	_	_	_	_
8	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	basal	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	PMA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	RA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	inducible	_	ADJ	_	Number=Sing	_	_	_	_
19	CD23	_	PROPN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	dose	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	manner	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	U	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	937	_	NUM	_	NumType=Card	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	RA	_	PROPN	_	Number=Sing	_	_	_	_
11	strongly	_	ADV	_	_	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	CD23	_	NOUN	_	Number=Sing	_	_	_	_
17	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whereas	_	SCONJ	_	_	_	_	_	_
22	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
23	completely	_	ADV	_	_	_	_	_	_
24	lacked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
26	CD14	_	NOUN	_	Number=Sing	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	surface	_	NOUN	_	Number=Sing	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	VitD3	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	PMA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	CD14	_	PROPN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	temporal	_	ADJ	_	Degree=Pos	_	_	_	_
18	consequence	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	RA	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	there	_	PRON	_	_	_	_	_	_
6	exists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	functional	_	ADJ	_	Degree=Pos	_	_	_	_
9	antagonism	_	NOUN	_	Number=Sing	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	VitD3	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	RA	_	PROPN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	have	_	VERB	_	VerbForm=Inf	_	_	_	_
17	important	_	ADJ	_	Degree=Pos	_	_	_	_
18	implications	_	NOUN	_	Number=Plur	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	regulation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	certain	_	ADJ	_	Degree=Pos	_	_	_	_
24	immune	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	responses	_	NOUN	_	Number=Plur	_	_	_	_
28	through	_	ADP	_	_	_	_	_	_
29	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
30	inverse	_	ADJ	_	Degree=Pos	_	_	_	_
31	effects	_	NOUN	_	Number=Plur	_	_	_	_
32	on	_	ADP	_	_	_	_	_	_
33	CD14	_	PROPN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	CD23	_	PROPN	_	Number=Sing	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	expression	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012433	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
2	blood	_	NOUN	_	Number=Sing	_	_	_	_
3	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	patients	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	diabetic	_	ADJ	_	Degree=Pos	_	_	_	_
10	nephropathy	_	NOUN	_	Number=Sing	_	_	_	_
11	show	_	NOUN	_	Number=Sing	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	stress	_	NOUN	_	Number=Sing	_	_	_	_
19	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
3	stress	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	development	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	late	_	ADJ	_	Degree=Pos	_	_	_	_
22	diabetic	_	ADJ	_	Degree=Pos	_	_	_	_
23	complications	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
5	stress	_	NOUN	_	Number=Sing	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	evident	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	patients	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	diabetic	_	ADJ	_	Degree=Pos	_	_	_	_
17	nephropathy	_	NOUN	_	Number=Sing	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
22	Mobility	_	NOUN	_	Number=Sing	_	_	_	_
23	Shift	_	PROPN	_	Number=Sing	_	_	_	_
24	Assay	_	PROPN	_	Number=Sing	_	_	_	_
25	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	semiquantitative	_	ADJ	_	Degree=Pos	_	_	_	_
27	detection	_	NOUN	_	Number=Sing	_	_	_	_
28	system	_	NOUN	_	Number=Sing	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	enabled	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	us	_	PRON	_	Case=Acc|Number=Plur|Person=1|PronType=Prs	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	ex	_	NOUN	_	Number=Sing	_	_	_	_
40	vivo	_	NOUN	_	Number=Sing	_	_	_	_
41	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
43	blood	_	NOUN	_	Number=Sing	_	_	_	_
44	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	33	_	NUM	_	NumType=Card	_	_	_	_
4	patients	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	diabetes	_	NOUN	_	Number=Sing	_	_	_	_
7	mellitus	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	Type	_	NOUN	_	Number=Sing	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Type	_	NOUN	_	Number=Sing	_	_	_	_
13	II	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Patients	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	diabetic	_	ADJ	_	Degree=Pos	_	_	_	_
4	nephropathy	_	NOUN	_	Number=Sing	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	Electrophoretic	_	ADJ	_	Number=Sing	_	_	_	_
14	Mobility	_	NOUN	_	Number=Sing	_	_	_	_
15	Shift	_	PROPN	_	Number=Sing	_	_	_	_
16	Assays	_	PROPN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	stronger	_	ADJ	_	Degree=Cmp	_	_	_	_
19	immunohistological	_	ADJ	_	Degree=Pos	_	_	_	_
20	staining	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaBp65	_	NOUN	_	NumType=Card	_	_	_	_
26	than	_	ADP	_	_	_	_	_	_
27	patients	_	NOUN	_	Number=Plur	_	_	_	_
28	without	_	ADP	_	_	_	_	_	_
29	renal	_	ADJ	_	Degree=Pos	_	_	_	_
30	complications	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	degree	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	albuminuria	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	r	_	NOUN	_	Number=Sing	_	_	_	_
14	=	_	SYM	_	_	_	_	_	_
15	0.316	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	thrombomodulin	_	ADJ	_	Degree=Pos	_	_	_	_
20	plasma	_	NOUN	_	Number=Sing	_	_	_	_
21	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	r	_	NOUN	_	_	_	_	_	_
24	=	_	SYM	_	_	_	_	_	_
25	0.33	_	NUM	_	NumType=Card	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	indicative	_	ADJ	_	Degree=Pos	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	albuminuria	_	NOUN	_	Number=Sing	_	_	_	_
31	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
33	dysfunction	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	3	_	NUM	_	NumType=Card	_	_	_	_
4	day	_	NOUN	_	Number=Sing	_	_	_	_
5	intervention	_	NOUN	_	Number=Sing	_	_	_	_
6	study	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	600	_	NUM	_	NumType=Card	_	_	_	_
10	mg	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
14	thioctic	_	ADJ	_	Number=Sing	_	_	_	_
15	acid	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	lipoic	_	NOUN	_	Number=Sing	_	_	_	_
20	acid	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	per	_	ADP	_	_	_	_	_	_
23	day	_	NOUN	_	Number=Sing	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	given	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	nine	_	NUM	_	NumType=Card	_	_	_	_
28	patients	_	NOUN	_	Number=Plur	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	diabetic	_	ADJ	_	Degree=Pos	_	_	_	_
31	nephropathy	_	NOUN	_	Number=Sing	_	_	_	_
32	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
33	stress	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	plasma	_	NOUN	_	Number=Sing	_	_	_	_
36	samples	_	NOUN	_	Number=Plur	_	_	_	_
37	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
38	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	by	_	ADP	_	_	_	_	_	_
40	48	_	NUM	_	NumType=Card	_	_	_	_
41	%	_	SYM	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	NF	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
46	binding	_	NOUN	_	Number=Sing	_	_	_	_
47	activity	_	NOUN	_	Number=Sing	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	ex	_	NOUN	_	Number=Sing	_	_	_	_
50	vivo	_	NOUN	_	Number=Sing	_	_	_	_
51	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
52	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
53	blood	_	NOUN	_	Number=Sing	_	_	_	_
54	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
55	cells	_	NOUN	_	Number=Plur	_	_	_	_
56	by	_	ADP	_	_	_	_	_	_
57	38	_	NUM	_	NumType=Card	_	_	_	_
58	%	_	SYM	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	ex	_	NOUN	_	Number=Sing	_	_	_	_
14	vivo	_	NOUN	_	Number=Sing	_	_	_	_
15	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
17	blood	_	NOUN	_	Number=Sing	_	_	_	_
18	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	patients	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	diabetes	_	NOUN	_	Number=Plur	_	_	_	_
24	mellitus	_	NOUN	_	Number=Sing	_	_	_	_
25	correlates	_	VERB	_	Number=Plur	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	degree	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	diabetic	_	ADJ	_	Degree=Pos	_	_	_	_
31	nephropathy	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	at	_	ADV	_	_	_	_	_	_
7	least	_	ADV	_	Degree=Sup	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	part	_	ADJ	_	Degree=Pos	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
13	stress	_	NOUN	_	Number=Sing	_	_	_	_
14	since	_	ADP	_	_	_	_	_	_
15	thioctic	_	ADJ	_	Degree=Pos	_	_	_	_
16	acid	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	lipoic	_	ADJ	_	Number=Sing	_	_	_	_
21	acid	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	NF	_	NUM	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012434	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
2	stress	_	NOUN	_	Number=Sing	_	_	_	_
3	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	activities	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Effects	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
4	stress	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	signal	_	NOUN	_	Number=Sing	_	_	_	_
10	transduction	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	quiescent	_	ADJ	_	Degree=Pos	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	blood	_	NOUN	_	Number=Sing	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	subjected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	:	_	PUNCT	_	_	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	i	_	X	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	acute	_	VERB	_	Degree=Pos	_	_	_	_
15	exposure	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	hydrogen	_	NOUN	_	Degree=Pos	_	_	_	_
18	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
19	;	_	PUNCT	_	_	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	ii	_	X	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
24	exposure	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	hydrogen	_	NOUN	_	Degree=Pos	_	_	_	_
27	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
28	;	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	iii	_	X	_	_	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	acute	_	ADJ	_	Degree=Pos	_	_	_	_
34	exposure	_	NOUN	_	Number=Sing	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	ionizing	_	VERB	_	VerbForm=Ger	_	_	_	_
37	radiation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	then	_	ADV	_	PronType=Dem	_	_	_	_
5	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	6	_	NUM	_	NumType=Card	_	_	_	_
8	h	_	NOUN	_	Number=Plur	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	activities	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
10	mobility	_	NOUN	_	Number=Sing	_	_	_	_
11	shift	_	NOUN	_	Number=Sing	_	_	_	_
12	assay	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	three	_	NUM	_	NumType=Card	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	:	_	PUNCT	_	_	_	_	_	_

1	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	AP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	all	_	DET	_	_	_	_	_	_
16	three	_	NUM	_	NumType=Card	_	_	_	_
17	modes	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
20	stress	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	exhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	lipid	_	ADJ	_	Degree=Pos	_	_	_	_
5	peroxidation	_	NOUN	_	Number=Sing	_	_	_	_
6	only	_	ADV	_	_	_	_	_	_
7	upon	_	ADP	_	_	_	_	_	_
8	exposure	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	lowest	_	ADJ	_	Degree=Sup	_	_	_	_
12	level	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	hydrogen	_	NOUN	_	Number=Sing	_	_	_	_
15	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
16	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	20	_	NUM	_	NumType=Card	_	_	_	_
19	microM	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	three	_	NUM	_	NumType=Card	_	_	_	_
3	modes	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
6	stress	_	NOUN	_	Number=Sing	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	catalase	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	only	_	ADJ	_	Degree=Pos	_	_	_	_
3	exception	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	hydrogen	_	NOUN	_	Number=Sing	_	_	_	_
6	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
7	at	_	ADP	_	_	_	_	_	_
8	20	_	NUM	_	NumType=Card	_	_	_	_
9	microM	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
15	catalase	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	i	_	X	_	_	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	suppression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	functions	_	NOUN	_	Number=Plur	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	potentially	_	ADV	_	_	_	_	_	_
16	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	marker	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	exposure	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
24	stress	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	effects	_	NOUN	_	Number=Plur	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
31	;	_	PUNCT	_	_	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	ii	_	X	_	_	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	lipid	_	ADJ	_	Degree=Pos	_	_	_	_
36	peroxidation	_	NOUN	_	Number=Sing	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	only	_	ADV	_	_	_	_	_	_
39	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	human	_	ADJ	_	Degree=Pos	_	_	_	_
42	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
43	upon	_	ADP	_	_	_	_	_	_
44	exposure	_	NOUN	_	Number=Sing	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	weak	_	ADJ	_	Degree=Pos	_	_	_	_
47	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
48	stress	_	NOUN	_	Number=Sing	_	_	_	_
49	which	_	PRON	_	PronType=Rel	_	_	_	_
50	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
51	not	_	PART	_	_	_	_	_	_
52	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
53	catalase	_	NOUN	_	Degree=Pos	_	_	_	_
54	activity	_	NOUN	_	Number=Sing	_	_	_	_
55	;	_	PUNCT	_	_	_	_	_	_
56	(	_	PUNCT	_	_	_	_	_	_
57	iii	_	X	_	_	_	_	_	_
58	)	_	PUNCT	_	_	_	_	_	_
59	therefore	_	ADV	_	_	_	_	_	_
60	,	_	PUNCT	_	_	_	_	_	_
61	transcription	_	NOUN	_	Number=Sing	_	_	_	_
62	factor	_	NOUN	_	Number=Sing	_	_	_	_
63	DNA	_	PROPN	_	Number=Sing	_	_	_	_
64	-	_	PUNCT	_	_	_	_	_	_
65	binding	_	NOUN	_	Number=Sing	_	_	_	_
66	activities	_	NOUN	_	Number=Plur	_	_	_	_
67	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
68	more	_	ADV	_	_	_	_	_	_
69	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
70	to	_	ADP	_	_	_	_	_	_
71	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
72	stress	_	NOUN	_	Number=Sing	_	_	_	_
73	than	_	ADP	_	_	_	_	_	_
74	lipid	_	ADJ	_	Degree=Pos	_	_	_	_
75	peroxidation	_	NOUN	_	Number=Sing	_	_	_	_
76	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012440	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	during	_	ADP	_	_	_	_	_	_
8	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
9	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Cells	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
7	lineage	_	NOUN	_	Number=Sing	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	targets	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	infection	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
7	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	lines	_	NOUN	_	Number=Plur	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
15	esters	_	NOUN	_	Number=Plur	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	tumour	_	NOUN	_	Number=Sing	_	_	_	_
18	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	TNF	_	PROPN	_	Number=Sing	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
31	factor	_	NOUN	_	Number=Sing	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	parallel	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	such	_	ADJ	_	Degree=Pos	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	monitored	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	using	_	VERB	_	VerbForm=Ger	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	HIV	_	ADJ	_	Number=Sing	_	_	_	_
14	long	_	ADJ	_	Degree=Pos	_	_	_	_
15	terminal	_	NOUN	_	Number=Sing	_	_	_	_
16	repeat	_	ADJ	_	Degree=Pos	_	_	_	_
17	reporter	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	construct	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	such	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	under	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	influence	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Also	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	promonocyte	_	NOUN	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	line	_	NOUN	_	Number=Sing	_	_	_	_
8	chronically	_	ADV	_	_	_	_	_	_
9	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
27	ester	_	NOUN	_	Number=Sing	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	TNF	_	PROPN	_	Number=Sing	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	lines	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
10	esters	_	NOUN	_	Number=Plur	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Such	_	DET	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	process	_	NOUN	_	Number=Sing	_	_	_	_
4	may	_	AUX	_	VerbForm=Fin	_	_	_	_
5	have	_	VERB	_	VerbForm=Inf	_	_	_	_
6	fundamental	_	ADJ	_	Degree=Pos	_	_	_	_
7	implications	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
10	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	vivo	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	important	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	disease	_	NOUN	_	Number=Sing	_	_	_	_
19	progression	_	NOUN	_	Number=Sing	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	opportunistic	_	ADJ	_	Degree=Pos	_	_	_	_
23	infections	_	NOUN	_	Number=Plur	_	_	_	_
24	directly	_	ADV	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	indirectly	_	ADV	_	_	_	_	_	_
27	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
28	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012441	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Hypoxia	_	PROPN	_	Number=Sing	_	_	_	_
2	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	through	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	kappa	_	VERB	_	Number=Sing	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
20	residues	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	response	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	stress	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	such	_	ADJ	_	Degree=Pos	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	wide	_	ADJ	_	Degree=Pos	_	_	_	_
30	variety	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	early	_	ADJ	_	Degree=Pos	_	_	_	_
33	response	_	NOUN	_	Number=Sing	_	_	_	_
34	genes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	exposure	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	0.02	_	NUM	_	NumType=Card	_	_	_	_
15	%	_	SYM	_	Number=Sing	_	_	_	_
16	O2	_	NUM	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	results	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	kappa	_	VERB	_	Number=Sing	_	_	_	_
22	B	_	PROPN	_	Number=Sing	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	degradation	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	DNA	_	NOUN	_	Number=Sing	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	activity	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	reporter	_	NOUN	_	Number=Sing	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	construct	_	NOUN	_	Number=Sing	_	_	_	_
42	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
43	two	_	NUM	_	NumType=Card	_	_	_	_
44	NF	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	kappa	_	NOUN	_	Number=Sing	_	_	_	_
47	B	_	NOUN	_	Number=Sing	_	_	_	_
48	DNA	_	NOUN	_	Number=Sing	_	_	_	_
49	binding	_	NOUN	_	Number=Sing	_	_	_	_
50	sites	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
12	negative	_	ADJ	_	Degree=Pos	_	_	_	_
13	allele	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	c	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	Raf	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	Raf	_	NOUN	_	Number=Sing	_	_	_	_
22	301	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
26	kappa	_	VERB	_	Number=Sing	_	_	_	_
27	B	_	PROPN	_	Number=Sing	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	degradation	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	PROPN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	binding	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	kappa	_	NOUN	_	Number=Sing	_	_	_	_
41	B	_	NOUN	_	Number=Sing	_	_	_	_
42	reporter	_	NOUN	_	Number=Sing	_	_	_	_
43	constructs	_	VERB	_	Number=Plur	_	_	_	_
44	by	_	ADP	_	_	_	_	_	_
45	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	demonstrate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	direct	_	ADJ	_	Degree=Pos	_	_	_	_
5	link	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	changes	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	pattern	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	kappa	_	VERB	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
25	immunoprecipitated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
27	kappa	_	VERB	_	Number=Sing	_	_	_	_
28	B	_	PROPN	_	Number=Sing	_	_	_	_
29	alpha	_	NOUN	_	Number=Sing	_	_	_	_
30	after	_	ADP	_	_	_	_	_	_
31	varying	_	VERB	_	VerbForm=Ger	_	_	_	_
32	times	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	hypoxic	_	ADJ	_	Degree=Pos	_	_	_	_
35	exposure	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	that	_	SCONJ	_	_	_	_	_	_
39	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
40	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
41	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
42	status	_	NOUN	_	Number=Sing	_	_	_	_
43	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	during	_	ADP	_	_	_	_	_	_
45	hypoxic	_	ADJ	_	Degree=Pos	_	_	_	_
46	exposure	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transfer	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
7	phosphoryl	_	NOUN	_	Number=Sing	_	_	_	_
8	groups	_	NOUN	_	Number=Plur	_	_	_	_
9	onto	_	ADP	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	kappa	_	VERB	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	alpha	_	PROPN	_	Number=Sing	_	_	_	_
14	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	VERB	_	Number=Sing	_	_	_	_
17	B	_	PROPN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	degradation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	PROPN	_	Number=Sing	_	_	_	_
24	B	_	PROPN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	comparison	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	other	_	ADJ	_	Degree=Pos	_	_	_	_
5	activators	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	such	_	ADJ	_	Degree=Pos	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
14	myristate	_	NOUN	_	Number=Sing	_	_	_	_
15	acetate	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	tumor	_	NOUN	_	Number=Sing	_	_	_	_
18	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
22	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	detect	_	VERB	_	VerbForm=Inf	_	_	_	_
25	changes	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
29	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
30	status	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
33	kappa	_	VERB	_	Number=Sing	_	_	_	_
34	B	_	PROPN	_	Number=Sing	_	_	_	_
35	alpha	_	NOUN	_	Number=Sing	_	_	_	_
36	following	_	VERB	_	VerbForm=Ger	_	_	_	_
37	treatment	_	NOUN	_	Number=Sing	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	either	_	DET	_	_	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
42	agents	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	kappa	_	VERB	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	during	_	ADP	_	_	_	_	_	_
13	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	important	_	ADJ	_	Degree=Pos	_	_	_	_
17	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
18	step	_	NOUN	_	Number=Sing	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	precedes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
22	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	degradation	_	NOUN	_	Number=Sing	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	PROPN	_	Number=Sing	_	_	_	_
29	B.	_	PROPN	_	Number=Sing	_	_	_	_
30	Document	_	NOUN	_	Number=Sing	_	_	_	_
31	0030012443	_	NUM	_	NumType=Card	_	_	_	_
32	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	polymorphism	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	PRON	_	PronType=Rel	_	_	_	_
4	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	OCT	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	severe	_	ADJ	_	Degree=Pos	_	_	_	_
18	malaria	_	NOUN	_	Number=Sing	_	_	_	_
19	[	_	PUNCT	_	_	_	_	_	_
20	see	_	VERB	_	VerbForm=Inf	_	_	_	_
21	comments	_	NOUN	_	Number=Plur	_	_	_	_
22	]	_	PUNCT	_	_	_	_	_	_

1	Genetic	_	ADJ	_	Degree=Pos	_	_	_	_
2	variation	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	regions	_	NOUN	_	Number=Plur	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	postulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	influence	_	NOUN	_	VerbForm=Inf	_	_	_	_
11	susceptibility	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	infection	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
18	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	such	_	ADJ	_	Degree=Pos	_	_	_	_
22	polymorphisms	_	NOUN	_	Number=Plur	_	_	_	_
23	might	_	AUX	_	VerbForm=Fin	_	_	_	_
24	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	regulation	_	NOUN	_	Number=Sing	_	_	_	_
27	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Through	_	ADP	_	_	_	_	_	_
2	systematic	_	ADJ	_	Degree=Pos	_	_	_	_
3	DNA	_	PROPN	_	Number=Sing	_	_	_	_
4	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
10	tumour	_	NOUN	_	Number=Sing	_	_	_	_
11	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	region	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	single	_	ADJ	_	Degree=Pos	_	_	_	_
24	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
25	polymorphism	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	SNP	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	causes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	helix	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	turn	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	helix	_	NOUN	_	Number=Sing	_	_	_	_
37	transcription	_	NOUN	_	Number=Sing	_	_	_	_
38	factor	_	NOUN	_	Number=Sing	_	_	_	_
39	OCT	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	SYM	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	to	_	PART	_	_	_	_	_	_
43	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
44	to	_	ADP	_	_	_	_	_	_
45	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
46	novel	_	NOUN	_	Number=Sing	_	_	_	_
47	region	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	complex	_	ADJ	_	Degree=Pos	_	_	_	_
50	protein	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	DNA	_	NOUN	_	Number=Sing	_	_	_	_
53	interactions	_	NOUN	_	Number=Plur	_	_	_	_
54	and	_	CCONJ	_	_	_	_	_	_
55	alters	_	VERB	_	Number=Plur	_	_	_	_
56	gene	_	NOUN	_	Number=Sing	_	_	_	_
57	expression	_	NOUN	_	Number=Sing	_	_	_	_
58	in	_	ADP	_	_	_	_	_	_
59	human	_	ADJ	_	Degree=Pos	_	_	_	_
60	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	OCT	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	genotype	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	approximately	_	ADV	_	_	_	_	_	_
12	5	_	NUM	_	NumType=Card	_	_	_	_
13	%	_	SYM	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	Africans	_	PROPN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	fourfold	_	NOUN	_	Number=Sing	_	_	_	_
21	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	susceptibility	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	cerebral	_	ADJ	_	Degree=Pos	_	_	_	_
25	malaria	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	large	_	ADJ	_	Degree=Pos	_	_	_	_
28	case	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	control	_	NOUN	_	Number=Sing	_	_	_	_
31	studies	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	West	_	PROPN	_	Number=Sing	_	_	_	_
34	African	_	PROPN	_	Degree=Pos	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	East	_	ADJ	_	Number=Sing	_	_	_	_
37	African	_	ADJ	_	Degree=Pos	_	_	_	_
38	populations	_	NOUN	_	Number=Plur	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	after	_	ADP	_	_	_	_	_	_
41	correction	_	NOUN	_	Number=Sing	_	_	_	_
42	for	_	ADP	_	_	_	_	_	_
43	other	_	ADJ	_	Degree=Pos	_	_	_	_
44	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	TNF	_	NOUN	_	Number=Sing	_	_	_	_
46	polymorphisms	_	NOUN	_	Number=Plur	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	HLA	_	PROPN	_	Number=Sing	_	_	_	_
50	alleles	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012448	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	C5a	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	8	_	NUM	_	NumType=Card	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	C5a	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	potent	_	NOUN	_	Number=Sing	_	_	_	_
5	peptide	_	NOUN	_	Number=Sing	_	_	_	_
6	chemoattractant	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	8	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	8	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	secretion	_	NOUN	_	Number=Sing	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
20	blood	_	NOUN	_	Number=Sing	_	_	_	_
21	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Experiments	_	NOUN	_	Number=Plur	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	conducted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	C5a	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	8	_	NUM	_	NumType=Card	_	_	_	_
15	production	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	14	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	fold	_	VERB	_	VerbForm=Inf	_	_	_	_
22	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
23	than	_	ADP	_	_	_	_	_	_
24	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	hours	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	8	_	NUM	_	NumType=Card	_	_	_	_
4	secretion	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	8	_	NUM	_	NumType=Card	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	DNA	_	NOUN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	within	_	ADP	_	_	_	_	_	_
28	30	_	NUM	_	NumType=Card	_	_	_	_
29	minutes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	AP	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	but	_	CCONJ	_	_	_	_	_	_
5	not	_	ADV	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	C5a-stimulated	_	PROPN	_	Tense=Past|VerbForm=Part	_	_	_	_
19	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
20	;	_	PUNCT	_	_	_	_	_	_
21	however	_	ADV	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	maximal	_	NOUN	_	Number=Sing	_	_	_	_
28	at	_	ADP	_	_	_	_	_	_
29	4	_	NUM	_	NumType=Card	_	_	_	_
30	hours	_	NOUN	_	Number=Plur	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	less	_	ADV	_	Degree=Cmp	_	_	_	_
35	important	_	ADJ	_	Degree=Pos	_	_	_	_
36	role	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
40	production	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	8	_	NUM	_	NumType=Card	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	correlation	_	NOUN	_	Number=Sing	_	_	_	_
3	between	_	ADP	_	_	_	_	_	_
4	C5a-induced	_	ADJ	_	Degree=Pos	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	8	_	NUM	_	NumType=Card	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	RAW264.7	_	PROPN	_	Number=Sing	_	_	_	_
19	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	using	_	VERB	_	VerbForm=Ger	_	_	_	_
22	reporter	_	NOUN	_	Number=Sing	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	sequence	_	NOUN	_	Number=Sing	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	8	_	NUM	_	NumType=Card	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	regions	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	C5a	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	reporter	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	SCONJ	_	_	_	_	_	_
10	introducing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	mutations	_	NOUN	_	Number=Plur	_	_	_	_
12	into	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	sites	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	coexpression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
22	negative	_	ADJ	_	Degree=Pos	_	_	_	_
23	IkappaBalpha	_	NOUN	_	Number=Sing	_	_	_	_
24	construct	_	NOUN	_	Number=Sing	_	_	_	_
25	resistant	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	agonist	_	VERB	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Pertussis	_	PROPN	_	Number=Sing	_	_	_	_
2	toxin	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	ADP	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	ribosylates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Gi	_	NOUN	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	couple	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	C5a	_	PROPN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
21	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	C5a-induced	_	VERB	_	Degree=Pos	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	8	_	NUM	_	NumType=Card	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	little	_	ADJ	_	Degree=Pos	_	_	_	_
31	effect	_	NOUN	_	Number=Sing	_	_	_	_
32	on	_	ADP	_	_	_	_	_	_
33	C5a	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	calcium	_	NOUN	_	Number=Sing	_	_	_	_
37	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	RAW264.7	_	PROPN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	C5a	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	8	_	NUM	_	NumType=Card	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	primarily	_	ADV	_	_	_	_	_	_
27	through	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	pertussis	_	ADJ	_	Number=Sing	_	_	_	_
30	toxin	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	insensitive	_	ADJ	_	Degree=Pos	_	_	_	_
33	pathway	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012461	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	occupation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	MHC	_	PROPN	_	Number=Sing	_	_	_	_
7	class	_	NOUN	_	Number=Sing	_	_	_	_
8	II	_	NUM	_	Number=Sing	_	_	_	_
9	promoters	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	independent	_	ADJ	_	Degree=Pos	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	cooperative	_	ADJ	_	Degree=Pos	_	_	_	_
15	stabilization	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	bound	_	ADJ	_	Degree=Pos	_	_	_	_
21	multi-protein	_	ADJ	_	Number=Sing	_	_	_	_
22	complexes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Precise	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	MHC	_	PROPN	_	Number=Sing	_	_	_	_
5	class	_	NOUN	_	Number=Sing	_	_	_	_
6	II	_	PROPN	_	NumType=Card	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	control	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	immune	_	ADJ	_	Degree=Pos	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
3	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
4	behaves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	master	_	NOUN	_	Number=Sing	_	_	_	_
8	controller	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
13	MHC	_	PROPN	_	Number=Sing	_	_	_	_
14	class	_	NOUN	_	Number=Sing	_	_	_	_
15	II	_	NUM	_	NumType=Card	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
21	s	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	exact	_	ADJ	_	_	_	_	_	_
23	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	action	_	NOUN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	MHC	_	PROPN	_	Number=Sing	_	_	_	_
4	class	_	NOUN	_	Number=Sing	_	_	_	_
5	II	_	NUM	_	NumType=Card	_	_	_	_
6	promoters	_	NOUN	_	Number=Plur	_	_	_	_
7	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	at	_	ADV	_	_	_	_	_	_
11	least	_	ADV	_	Degree=Sup	_	_	_	_
12	three	_	NUM	_	NumType=Card	_	_	_	_
13	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
14	multi-protein	_	ADJ	_	Number=Sing	_	_	_	_
15	complexes	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	RFX	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	X2BP	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	Y	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	stability	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	results	_	NOUN	_	Number=Plur	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	cooperative	_	ADJ	_	Degree=Pos	_	_	_	_
13	interactions	_	NOUN	_	Number=Plur	_	_	_	_
14	between	_	ADP	_	_	_	_	_	_
15	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	MHC	_	PROPN	_	Number=Sing	_	_	_	_
10	class	_	NOUN	_	Number=Sing	_	_	_	_
11	II	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	triggers	_	VERB	_	Number=Plur	_	_	_	_
15	occupation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	promoters	_	NOUN	_	Number=Plur	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	complexes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	observation	_	NOUN	_	Number=Sing	_	_	_	_
3	raised	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	possibility	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	effect	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	occupation	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	effect	_	NOUN	_	Number=Sing	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	cooperative	_	ADJ	_	Degree=Pos	_	_	_	_
22	stabilization	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	DNA	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	bound	_	ADJ	_	Degree=Pos	_	_	_	_
28	multi-protein	_	ADJ	_	Number=Sing	_	_	_	_
29	complexes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	however	_	ADV	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	presence	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
11	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	stability	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	order	_	NOUN	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	complex	_	NOUN	_	Number=Sing	_	_	_	_
23	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	DNA	_	NOUN	_	Number=Sing	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	RFX	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	X2BP	_	PROPN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	Y	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	occupancy	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	such	_	ADJ	_	Degree=Pos	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	effect	_	NOUN	_	Number=Sing	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	chromatin	_	ADJ	_	Number=Sing	_	_	_	_
18	structure	_	NOUN	_	Number=Sing	_	_	_	_
19	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	accessibility	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	MHC	_	PROPN	_	Number=Sing	_	_	_	_
25	class	_	NOUN	_	Number=Sing	_	_	_	_
26	II	_	NUM	_	NumType=Card	_	_	_	_
27	promoters	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	facilitate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	occupation	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	undissociable	_	ADJ	_	Degree=Pos	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
14	potential	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	since	_	SCONJ	_	_	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	normal	_	ADJ	_	Degree=Pos	_	_	_	_
25	occupation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	MHC	_	PROPN	_	Number=Sing	_	_	_	_
28	class	_	NOUN	_	Number=Sing	_	_	_	_
29	II	_	NUM	_	Number=Sing	_	_	_	_
30	promoters	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	B	_	ADJ	_	Number=Sing	_	_	_	_
33	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012465	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	bacterial	_	ADJ	_	Number=Sing	_	_	_	_
10	LPS	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	interferon	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	gamma	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	GM	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	CSF	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	necessity	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	overcome	_	VERB	_	VerbForm=Inf	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	action	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
29	proteases	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	actively	_	ADV	_	_	_	_	_	_
8	transcribe	_	VERB	_	VerbForm=Inf	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	number	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	early	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	particular	_	ADJ	_	Degree=Pos	_	_	_	_
19	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
20	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
21	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	chemokines	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	high	_	ADJ	_	Degree=Pos	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	affinity	_	NOUN	_	Number=Sing	_	_	_	_
30	surface	_	NOUN	_	Number=Sing	_	_	_	_
31	receptor	_	NOUN	_	Number=Sing	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	IgG	_	PROPN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	FcgammaRI	_	PROPN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	little	_	ADV	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	date	_	NOUN	_	Number=Sing	_	_	_	_
7	about	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	regulation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	several	_	ADJ	_	Degree=Pos	_	_	_	_
17	indications	_	NOUN	_	Number=Plur	_	_	_	_
18	point	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factors	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	such	_	ADJ	_	Degree=Pos	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	members	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	STAT	_	NOUN	_	Number=Sing	_	_	_	_
37	families	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	whether	_	SCONJ	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	become	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	activated	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	under	_	ADP	_	_	_	_	_	_
14	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	conditions	_	NOUN	_	Number=Plur	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Unexpectedly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	conventional	_	ADJ	_	Degree=Pos	_	_	_	_
7	procedures	_	NOUN	_	Number=Plur	_	_	_	_
8	employed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	prepare	_	VERB	_	VerbForm=Inf	_	_	_	_
11	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
12	extracts	_	NOUN	_	Number=Plur	_	_	_	_
13	cause	_	VERB	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	release	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	activities	_	NOUN	_	Number=Plur	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	normally	_	ADV	_	_	_	_	_	_
22	stored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
25	granules	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	degradation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	various	_	ADJ	_	Degree=Pos	_	_	_	_
33	NF	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	Rel	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	STAT	_	NOUN	_	Number=Sing	_	_	_	_
40	proteins	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	circumvent	_	VERB	_	VerbForm=Inf	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	problem	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	developed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
10	procedure	_	NOUN	_	Number=Sing	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	allowed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	us	_	PRON	_	Case=Acc|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	show	_	VERB	_	VerbForm=Inf	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	LPS	_	PROPN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
23	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	DNA	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	activity	_	NOUN	_	Number=Sing	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	essentially	_	ADV	_	_	_	_	_	_
34	consists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	p50	_	NOUN	_	Number=Sing	_	_	_	_
37	/	_	PUNCT	_	_	_	_	_	_
38	RelA	_	NOUN	_	Number=Sing	_	_	_	_
39	dimers	_	NOUN	_	Number=Plur	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	that	_	SCONJ	_	_	_	_	_	_
43	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
44	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	binding	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
49	homodimers	_	NOUN	_	Number=Plur	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	IFNgamma	_	PROPN	_	Number=Sing	_	_	_	_
53	response	_	NOUN	_	Number=Sing	_	_	_	_
54	region	_	NOUN	_	Number=Sing	_	_	_	_
55	of	_	ADP	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	FcgammaRI	_	PROPN	_	Number=Sing	_	_	_	_
58	promoter	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
7	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	GM	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	CSF	_	NOUN	_	Number=Sing	_	_	_	_
12	results	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	formation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	DNA	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Collectively	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	current	_	ADJ	_	Degree=Pos	_	_	_	_
5	findings	_	NOUN	_	Number=Plur	_	_	_	_
6	open	_	ADJ	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	new	_	ADJ	_	Degree=Pos	_	_	_	_
8	perspectives	_	NOUN	_	Number=Plur	_	_	_	_
9	about	_	ADP	_	_	_	_	_	_
10	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	likely	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	procedure	_	NOUN	_	Number=Sing	_	_	_	_
6	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	herein	_	ADV	_	_	_	_	_	_
8	could	_	AUX	_	VerbForm=Fin	_	_	_	_
9	prove	_	VERB	_	VerbForm=Inf	_	_	_	_
10	useful	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	other	_	ADJ	_	Degree=Pos	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	types	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	high	_	ADJ	_	Degree=Pos	_	_	_	_
18	levels	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
21	proteases	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012472	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	HS2	_	PROPN	_	Number=Sing	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	genome	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	hypersensitive	_	ADJ	_	Degree=Pos	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	HS2	_	PROPN	_	Number=Sing	_	_	_	_
13	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
14	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
20	beta	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	like	_	ADP	_	Degree=Pos	_	_	_	_
23	globin	_	PROPN	_	Degree=Pos	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	10	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	SYM	_	_	_	_	_	_
27	50	_	NUM	_	NumType=Card	_	_	_	_
28	kilobases	_	NOUN	_	Number=Plur	_	_	_	_
29	away	_	ADV	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HS2	_	NOUN	_	Number=Sing	_	_	_	_
5	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
6	function	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	employs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	RNA	_	PROPN	_	Number=Sing	_	_	_	_
6	protection	_	NOUN	_	Number=Sing	_	_	_	_
7	assays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	status	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	HS2	_	NOUN	_	Number=Sing	_	_	_	_
16	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
20	chloramphenicol	_	NOUN	_	Number=Sing	_	_	_	_
21	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	CAT	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
3	K562	_	NUM	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	HS2	_	NOUN	_	Number=Sing	_	_	_	_
9	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	active	_	ADJ	_	Degree=Pos	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	HS2	_	PROPN	_	Number=Sing	_	_	_	_
15	sequence	_	NOUN	_	Number=Sing	_	_	_	_
16	directs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	long	_	ADJ	_	Degree=Pos	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	initiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	apparently	_	ADV	_	_	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	within	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	elongated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	through	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	intervening	_	VERB	_	VerbForm=Ger	_	_	_	_
36	DNA	_	NOUN	_	Number=Sing	_	_	_	_
37	into	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	cis	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	CAT	_	NOUN	_	Number=Sing	_	_	_	_
43	gene	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	nonerythroid	_	ADJ	_	Degree=Pos	_	_	_	_
3	HL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	60	_	NUM	_	NumType=Card	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	HS2	_	NOUN	_	Number=Sing	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	long	_	ADJ	_	Degree=Pos	_	_	_	_
16	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
17	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Splitting	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	HS2	_	PROPN	_	Number=Sing	_	_	_	_
4	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
5	between	_	ADP	_	_	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	tandem	_	NOUN	_	Number=Sing	_	_	_	_
8	Ap1	_	NOUN	_	Number=Sing	_	_	_	_
9	sites	_	NOUN	_	Number=Plur	_	_	_	_
10	abolishes	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	group	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	long	_	ADJ	_	Degree=Pos	_	_	_	_
18	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
19	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	results	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	loss	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
26	function	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	silencing	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	cis	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	CAT	_	NOUN	_	Number=Sing	_	_	_	_
36	gene	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	SCONJ	_	_	_	_	_	_
2	directing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	RNA	_	PROPN	_	Number=Sing	_	_	_	_
7	through	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	intervening	_	VERB	_	VerbForm=Ger	_	_	_	_
10	DNA	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	tracking	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	HS2	_	PROPN	_	Number=Sing	_	_	_	_
23	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
24	may	_	AUX	_	VerbForm=Fin	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	i	_	X	_	_	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	open	_	VERB	_	VerbForm=Inf	_	_	_	_
29	up	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	chromatin	_	ADJ	_	Degree=Pos	_	_	_	_
32	structure	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	domain	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	ii	_	X	_	_	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	deliver	_	VERB	_	VerbForm=Inf	_	_	_	_
42	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
43	binding	_	VERB	_	Number=Sing	_	_	_	_
44	proteins	_	NOUN	_	Number=Plur	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	promoter	_	NOUN	_	Number=Sing	_	_	_	_
48	sequence	_	NOUN	_	Number=Sing	_	_	_	_
49	where	_	ADV	_	PronType=Rel	_	_	_	_
50	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
51	may	_	AUX	_	VerbForm=Fin	_	_	_	_
52	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	transcription	_	NOUN	_	Number=Sing	_	_	_	_
55	of	_	ADP	_	_	_	_	_	_
56	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
57	gene	_	NOUN	_	Number=Sing	_	_	_	_
58	at	_	ADP	_	_	_	_	_	_
59	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
60	cap	_	NOUN	_	Number=Sing	_	_	_	_
61	site	_	NOUN	_	Number=Sing	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012485	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Low	_	ADJ	_	Degree=Pos	_	_	_	_
2	CD3	_	PROPN	_	Number=Sing	_	_	_	_
3	+	_	SYM	_	_	_	_	_	_
4	CD28-induced	_	VERB	_	NumType=Card	_	_	_	_
5	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	production	_	NOUN	_	Number=Sing	_	_	_	_
9	correlates	_	VERB	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
13	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
14	intermediate	_	ADJ	_	Degree=Pos	_	_	_	_
15	formation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	capacity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	secrete	_	VERB	_	VerbForm=Inf	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	_	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
19	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	variable	_	ADJ	_	Degree=Pos	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	analysed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	production	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	neonatal	_	ADJ	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	adult	_	NOUN	_	Number=Sing	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	using	_	VERB	_	VerbForm=Ger	_	_	_	_
15	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
16	activator	_	NOUN	_	Number=Sing	_	_	_	_
17	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
18	ester	_	NOUN	_	Number=Sing	_	_	_	_
19	+	_	SYM	_	_	_	_	_	_
20	calcium	_	NOUN	_	Number=Sing	_	_	_	_
21	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	PDBu	_	PROPN	_	Number=Sing	_	_	_	_
24	+	_	SYM	_	_	_	_	_	_
25	iono	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	receptor	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
31	anti-CD3/anti-CD3	_	X	_	Number=Sing	_	_	_	_
32	+	_	SYM	_	_	_	_	_	_
33	anti-CD28	_	ADJ	_	NumType=Card	_	_	_	_
34	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	PDBu	_	PROPN	_	Number=Sing	_	_	_	_
2	+	_	CCONJ	_	_	_	_	_	_
3	iono	_	PROPN	_	Number=Sing	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	equally	_	ADV	_	_	_	_	_	_
6	high	_	ADJ	_	Degree=Pos	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	both	_	DET	_	_	_	_	_	_
13	groups	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	when	_	ADV	_	PronType=Int	_	_	_	_
17	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	plate	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	bound	_	ADJ	_	Degree=Pos	_	_	_	_
22	anti-CD3	_	ADJ	_	Number=Sing	_	_	_	_
23	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
24	antibody	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	mAb	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	secretion	_	NOUN	_	Number=Sing	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
38	undetectable	_	ADJ	_	Degree=Pos	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	adult	_	ADJ	_	Degree=Pos	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	low	_	ADJ	_	Degree=Pos	_	_	_	_
44	amounts	_	NOUN	_	Number=Plur	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	IL	_	NOUN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	2	_	NUM	_	NumType=Card	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	mean	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
51	331	_	NUM	_	NumType=Card	_	_	_	_
52	+/-	_	SYM	_	_	_	_	_	_
53	86	_	NUM	_	NumType=Card	_	_	_	_
54	pg	_	NOUN	_	Number=Sing	_	_	_	_
55	/	_	SYM	_	_	_	_	_	_
56	ml	_	NOUN	_	Number=Sing	_	_	_	_
57	)	_	PUNCT	_	_	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	anti-CD28	_	PROPN	_	Number=Sing	_	_	_	_
5	mAb	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	markedly	_	ADV	_	_	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	both	_	DET	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	types	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
30	T	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	clearly	_	ADV	_	_	_	_	_	_
34	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
35	than	_	ADP	_	_	_	_	_	_
36	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	adult	_	NOUN	_	Degree=Pos	_	_	_	_
39	T	_	NOUN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	respective	_	ADJ	_	Degree=Pos	_	_	_	_
43	mean	_	NOUN	_	Number=Sing	_	_	_	_
44	values	_	NOUN	_	Number=Plur	_	_	_	_
45	:	_	PUNCT	_	_	_	_	_	_
46	385	_	NUM	_	NumType=Card	_	_	_	_
47	+/-	_	SYM	_	_	_	_	_	_
48	109	_	NUM	_	NumType=Card	_	_	_	_
49	pg	_	NOUN	_	Number=Sing	_	_	_	_
50	/	_	PUNCT	_	_	_	_	_	_
51	ml	_	NOUN	_	Number=Sing	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	4494	_	NUM	_	NumType=Card	_	_	_	_
54	+/-	_	SYM	_	_	_	_	_	_
55	1199	_	NUM	_	NumType=Card	_	_	_	_
56	pg	_	NOUN	_	Number=Sing	_	_	_	_
57	/	_	SYM	_	_	_	_	_	_
58	ml	_	NOUN	_	Number=Sing	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	critical	_	ADJ	_	Degree=Pos	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	control	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	next	_	ADV	_	_	_	_	_	_
18	analysed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	translocation	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	adult	_	ADJ	_	Number=Sing	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	using	_	VERB	_	VerbForm=Ger	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
31	mobility	_	NOUN	_	Number=Sing	_	_	_	_
32	shift	_	NOUN	_	Number=Sing	_	_	_	_
33	assay	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	because	_	SCONJ	_	_	_	_	_	_
37	induction	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
40	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
41	intermediates	_	NOUN	_	Number=Plur	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	ROI	_	PROPN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
46	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
47	for	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	activation	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	NF	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	kappa	_	NOUN	_	Number=Sing	_	_	_	_
54	B	_	NOUN	_	Number=Sing	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
57	also	_	ADV	_	_	_	_	_	_
58	analysed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
59	levels	_	NOUN	_	Number=Plur	_	_	_	_
60	of	_	ADP	_	_	_	_	_	_
61	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
62	ROI	_	NOUN	_	Number=Sing	_	_	_	_
63	in	_	ADP	_	_	_	_	_	_
64	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
65	cells	_	NOUN	_	Number=Plur	_	_	_	_
66	using	_	VERB	_	VerbForm=Ger	_	_	_	_
67	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
68	ROI	_	NOUN	_	Number=Sing	_	_	_	_
69	-	_	PUNCT	_	_	_	_	_	_
70	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
71	fluorochrome	_	NOUN	_	Number=Sing	_	_	_	_
72	DCFH	_	PROPN	_	Number=Sing	_	_	_	_
73	-	_	PUNCT	_	_	_	_	_	_
74	DA	_	PROPN	_	Number=Sing	_	_	_	_
75	and	_	CCONJ	_	_	_	_	_	_
76	flow	_	VERB	_	Number=Sing	_	_	_	_
77	cytometry	_	NOUN	_	Number=Sing	_	_	_	_
78	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	ROI	_	NOUN	_	Number=Sing	_	_	_	_
12	formation	_	NOUN	_	Number=Sing	_	_	_	_
13	after	_	ADP	_	_	_	_	_	_
14	anti-CD3	_	PROPN	_	Degree=Pos	_	_	_	_
15	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	low	_	ADJ	_	Degree=Pos	_	_	_	_
18	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	adult	_	NOUN	_	Degree=Pos	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	although	_	SCONJ	_	_	_	_	_	_
26	addition	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	anti-CD28	_	ADJ	_	Number=Sing	_	_	_	_
29	mAb	_	NOUN	_	Number=Sing	_	_	_	_
30	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	induction	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	ROI	_	NOUN	_	Number=Sing	_	_	_	_
39	formation	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	levels	_	NOUN	_	Number=Plur	_	_	_	_
42	similar	_	ADJ	_	Degree=Pos	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	adults	_	NOUN	_	Number=Plur	_	_	_	_
47	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
48	not	_	PART	_	_	_	_	_	_
49	achieved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	PDBu	_	PROPN	_	Number=Sing	_	_	_	_
3	+	_	SYM	_	_	_	_	_	_
4	iono	_	PROPN	_	Number=Sing	_	_	_	_
5	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	similar	_	ADJ	_	Degree=Pos	_	_	_	_
11	ROI	_	NOUN	_	Number=Sing	_	_	_	_
12	formation	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	secretion	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	production	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	anti-CD3	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	anti-CD3	_	X	_	Number=Sing	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_
21	anti-CD28-mediated	_	ADJ	_	Degree=Pos	_	_	_	_
22	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	activators	_	NOUN	_	Number=Plur	_	_	_	_
27	can	_	AUX	_	VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	effectively	_	ADV	_	_	_	_	_	_
30	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	ROI	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappa	_	NOUN	_	Number=Sing	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	signalling	_	NOUN	_	Number=Sing	_	_	_	_
39	pathway	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
42	T	_	NOUN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012490	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Control	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NFATx1	_	PROPN	_	Number=Sing	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	translocation	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
12	domain	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	cis	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	elements	_	NOUN	_	Number=Plur	_	_	_	_
23	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	promoters	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	several	_	ADJ	_	Degree=Pos	_	_	_	_
29	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	NFATx1	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	which	_	PRON	_	PronType=Rel	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	preferentially	_	ADV	_	_	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	thymus	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
12	blood	_	NOUN	_	Number=Sing	_	_	_	_
13	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	one	_	NUM	_	NumType=Card	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	four	_	NUM	_	NumType=Card	_	_	_	_
19	members	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	NFAT	_	ADJ	_	Number=Sing	_	_	_	_
23	family	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	factors	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	performed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	domain	_	NOUN	_	Number=Sing	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NFATx1	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	SCONJ	_	_	_	_	_	_
9	examining	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	effects	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	deletion	_	NOUN	_	Number=Sing	_	_	_	_
14	mutations	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	NFATx1	_	PROPN	_	Number=Sing	_	_	_	_
5	DNA	_	NOUN	_	Number=Sing	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	interaction	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	polypeptides	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	central	_	ADJ	_	Degree=Pos	_	_	_	_
20	Rel	_	NOUN	_	Number=Sing	_	_	_	_
21	similarity	_	NOUN	_	Number=Sing	_	_	_	_
22	region	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	that	_	DET	_	_	_	_	_	_
25	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	deletions	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	either	_	CCONJ	_	_	_	_	_	_
33	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	N	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	terminal	_	NOUN	_	Number=Sing	_	_	_	_
37	domain	_	NOUN	_	Number=Sing	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
40	C	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	terminal	_	NOUN	_	Number=Sing	_	_	_	_
43	domain	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	presence	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	intrinsic	_	ADJ	_	Degree=Pos	_	_	_	_
50	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
51	activation	_	NOUN	_	Number=Sing	_	_	_	_
52	motifs	_	NOUN	_	Number=Plur	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	both	_	CCONJ	_	_	_	_	_	_
55	regions	_	NOUN	_	Number=Plur	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	potent	_	ADJ	_	Degree=Pos	_	_	_	_
6	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	within	_	ADP	_	_	_	_	_	_
9	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	N	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	terminal	_	NOUN	_	Number=Sing	_	_	_	_
13	domain	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	calcium	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	calmodulin	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
6	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	N	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	terminal	_	ADJ	_	Number=Sing	_	_	_	_
12	domain	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NFATx1	_	NOUN	_	Number=Sing	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
17	docking	_	NOUN	_	Number=Sing	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	reduction	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	size	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	indicative	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	NFATx1	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	mapped	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	less	_	ADJ	_	Degree=Cmp	_	_	_	_
9	than	_	ADP	_	_	_	_	_	_
10	60	_	NUM	_	NumType=Card	_	_	_	_
11	residues	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	motifs	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	conserved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	all	_	DET	_	_	_	_	_	_
20	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	deletion	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	NFATx1	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	mapped	_	VERB	_	Degree=Pos	_	_	_	_
12	60	_	NUM	_	NumType=Card	_	_	_	_
13	residues	_	NOUN	_	Number=Plur	_	_	_	_
14	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	translocation	_	NOUN	_	Number=Sing	_	_	_	_
19	independent	_	ADJ	_	Degree=Pos	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	calcium	_	NOUN	_	Number=Sing	_	_	_	_
22	signaling	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	model	_	NOUN	_	Number=Sing	_	_	_	_
6	proposing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	N-terminal	_	ADJ	_	Degree=Pos	_	_	_	_
10	domain	_	NOUN	_	Number=Sing	_	_	_	_
11	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	calcium	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
15	dependence	_	NOUN	_	Number=Sing	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	NFATx1	_	NOUN	_	Number=Sing	_	_	_	_
18	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	by	_	SCONJ	_	_	_	_	_	_
21	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
24	localization	_	NOUN	_	Number=Sing	_	_	_	_
25	through	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	module	_	NOUN	_	Number=Sing	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	associates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	target	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
39	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
40	activity	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012492	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Precise	_	ADJ	_	Degree=Pos	_	_	_	_
2	alignment	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	sites	_	NOUN	_	Number=Plur	_	_	_	_
5	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	mu	_	PRON	_	Number=Sing	_	_	_	_
8	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	B	_	ADJ	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
6	mu	_	X	_	_	_	_	_	_
7	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	chain	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	intronic	_	ADJ	_	Degree=Pos	_	_	_	_
12	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	defined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
5	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
6	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	muA	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	muE3	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	muB	_	NOUN	_	Number=Sing	_	_	_	_
14	sites	_	NOUN	_	Number=Plur	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	transactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	combination	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	ETS	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	domain	_	NOUN	_	Number=Sing	_	_	_	_
25	proteins	_	NOUN	_	Number=Plur	_	_	_	_
26	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	Ets	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	nonlymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	core	_	NOUN	_	Number=Sing	_	_	_	_
3	GGAAs	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	muA	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	muB	_	NOUN	_	Number=Sing	_	_	_	_
9	sites	_	NOUN	_	Number=Plur	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	separated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	30	_	NUM	_	NumType=Card	_	_	_	_
14	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	ETS	_	NOUN	_	Number=Sing	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
23	sites	_	NOUN	_	Number=Plur	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	same	_	ADJ	_	Degree=Pos	_	_	_	_
27	side	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	DNA	_	PROPN	_	Number=Sing	_	_	_	_
31	helix	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	necessity	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	appropriate	_	ADJ	_	Degree=Pos	_	_	_	_
7	spatial	_	ADJ	_	Degree=Pos	_	_	_	_
8	alignment	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	elements	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	using	_	VERB	_	VerbForm=Ger	_	_	_	_
14	mutated	_	ADJ	_	Degree=Pos	_	_	_	_
15	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	spacings	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	4	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	10	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	bp	_	NOUN	_	Number=Sing	_	_	_	_
8	insertion	_	NOUN	_	Number=Sing	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	muE3	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	muB	_	NOUN	_	Number=Sing	_	_	_	_
13	inactivated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	mu	_	NOUN	_	Number=Sing	_	_	_	_
16	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	S194	_	NUM	_	NumType=Card	_	_	_	_
19	plasma	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vitro	_	NOUN	_	Number=Sing	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	Ets	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	muE3	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	binding	_	NOUN	_	Number=Sing	_	_	_	_
40	protein	_	NOUN	_	Number=Sing	_	_	_	_
41	TFE3	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	alone	_	ADJ	_	_	_	_	_	_
44	or	_	CCONJ	_	_	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	pairwise	_	ADJ	_	Number=Sing	_	_	_	_
47	combinations	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Circular	_	ADJ	_	Degree=Pos	_	_	_	_
2	permutation	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	phasing	_	NOUN	_	Number=Sing	_	_	_	_
5	analyses	_	NOUN	_	Number=Plur	_	_	_	_
6	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	PU.	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	ADV	_	_	_	_	_	_
13	TFE3	_	NUM	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	Ets	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	bends	_	NOUN	_	Number=Plur	_	_	_	_
19	mu	_	NOUN	_	Number=Sing	_	_	_	_
20	enhancer	_	VERB	_	Number=Sing	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	toward	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	major	_	ADJ	_	Degree=Pos	_	_	_	_
25	groove	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	requirement	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	precise	_	ADJ	_	Degree=Pos	_	_	_	_
8	spacing	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	muA	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	muB	_	NOUN	_	Number=Sing	_	_	_	_
14	elements	_	NOUN	_	Number=Plur	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	due	_	ADP	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	part	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	DNA	_	PROPN	_	Number=Sing	_	_	_	_
23	bend	_	NOUN	_	Number=Sing	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012495	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
5	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
6	IX	_	PROPN	_	Number=Sing	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	oncogenic	_	ADJ	_	Degree=Pos	_	_	_	_
11	Ets	_	NOUN	_	Number=Plur	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	Fli-1	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Glycoprotein	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	GP	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	IX	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	subunit	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	von	_	NOUN	_	Number=Sing	_	_	_	_
12	Willebrand	_	PROPN	_	Number=Sing	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	GPIb-V	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	IX	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	platelets	_	NOUN	_	Number=Plur	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	subendothelium	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	damaged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	blood	_	NOUN	_	Number=Sing	_	_	_	_
30	vessels	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	characterization	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	GPIX	_	PROPN	_	Number=Sing	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	functional	_	ADJ	_	Degree=Pos	_	_	_	_
10	Ets	_	PROPN	_	Number=Plur	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	when	_	ADV	_	PronType=Int	_	_	_	_
15	disrupted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	Ets	_	NOUN	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	s	_	X	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	regulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	GPIX	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	transient	_	ADJ	_	Degree=Pos	_	_	_	_
6	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	several	_	ADJ	_	Degree=Pos	_	_	_	_
9	GPIX	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	reporter	_	NOUN	_	Number=Sing	_	_	_	_
13	constructs	_	VERB	_	Number=Plur	_	_	_	_
14	into	_	ADP	_	_	_	_	_	_
15	293T	_	ADJ	_	NumType=Card	_	_	_	_
16	kidney	_	NOUN	_	Number=Sing	_	_	_	_
17	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	Fli	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	vector	_	NOUN	_	Number=Sing	_	_	_	_
25	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	oncogenic	_	ADJ	_	Degree=Pos	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	Fli	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	can	_	AUX	_	VerbForm=Fin	_	_	_	_
34	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	GPIX	_	PROPN	_	Number=Sing	_	_	_	_
37	promoter	_	NOUN	_	Number=Sing	_	_	_	_
38	when	_	ADV	_	PronType=Int	_	_	_	_
39	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	intact	_	NOUN	_	Degree=Pos	_	_	_	_
41	GPIX	_	NOUN	_	Number=Sing	_	_	_	_
42	Ets	_	NOUN	_	Number=Sing	_	_	_	_
43	site	_	NOUN	_	Number=Sing	_	_	_	_
44	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	present	_	ADJ	_	Degree=Pos	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	Fli	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	GPIX	_	PROPN	_	Number=Sing	_	_	_	_
11	Ets	_	NOUN	_	Number=Plur	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	antibody	_	ADJ	_	Number=Sing	_	_	_	_
17	supershift	_	NOUN	_	Number=Sing	_	_	_	_
18	experiments	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	extracts	_	NOUN	_	Number=Plur	_	_	_	_
22	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	erythroleukemia	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Comparative	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Fli	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	able	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	GPIbalpha	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	lesser	_	ADJ	_	Degree=Cmp	_	_	_	_
20	extent	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	GPIIb	_	NOUN	_	Number=Sing	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Immunoblot	_	PROPN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	Fli	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	lysates	_	NOUN	_	Number=Plur	_	_	_	_
10	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	platelets	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Fli-1	_	PROPN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	immunohistochemically	_	ADV	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	megakaryocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	CD34	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	+	_	SYM	_	_	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	megakaryocyte	_	NOUN	_	Degree=Pos	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	thrombopoietin	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Fli	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	likely	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	lineage	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	specific	_	ADJ	_	Degree=Pos	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	during	_	ADP	_	_	_	_	_	_
17	megakaryocytopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012500	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Aspirin	_	PROPN	_	Number=Sing	_	_	_	_
2	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
7	molecule	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	E-selectin	_	VERB	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	tumor	_	NOUN	_	Number=Sing	_	_	_	_
19	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	TNF	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	PROPN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappa	_	NOUN	_	Number=Sing	_	_	_	_
43	B	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	salicylates	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	degradation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	kappa	_	VERB	_	Number=Sing	_	_	_	_
22	B	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
25	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	potential	_	ADJ	_	Degree=Pos	_	_	_	_
28	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	pathway	_	NOUN	_	Number=Sing	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	acetylsalicylate	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	human	_	ADJ	_	Degree=Pos	_	_	_	_
39	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
40	vein	_	NOUN	_	Number=Sing	_	_	_	_
41	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	AND	_	CCONJ	_	_	_	_	_	_
3	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	analyses	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	dose	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
9	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	NF	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
23	ranging	_	VERB	_	VerbForm=Ger	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	10	_	NUM	_	NumType=Card	_	_	_	_
28	mmol	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	L.	_	PROPN	_	Number=Sing	_	_	_	_
31	Induction	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	E-selectin	_	ADJ	_	Degree=Pos	_	_	_	_
38	surface	_	NOUN	_	Number=Sing	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	TNF	_	PROPN	_	Number=Sing	_	_	_	_
42	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
43	dose	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	dependently	_	ADV	_	_	_	_	_	_
46	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	by	_	ADP	_	_	_	_	_	_
48	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
49	over	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	same	_	ADJ	_	Degree=Pos	_	_	_	_
52	range	_	NOUN	_	Number=Sing	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	while	_	SCONJ	_	_	_	_	_	_
55	induction	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	intercellular	_	ADJ	_	Degree=Pos	_	_	_	_
58	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
59	molecule	_	NOUN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	1	_	NUM	_	NumType=Card	_	_	_	_
62	(	_	PUNCT	_	_	_	_	_	_
63	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
64	-	_	PUNCT	_	_	_	_	_	_
65	1	_	NUM	_	NumType=Card	_	_	_	_
66	)	_	PUNCT	_	_	_	_	_	_
67	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
68	hardly	_	ADV	_	_	_	_	_	_
69	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	Aspirin	_	PROPN	_	Number=Sing	_	_	_	_
2	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
5	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	since	_	SCONJ	_	_	_	_	_	_
11	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
12	dose	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependently	_	ADV	_	_	_	_	_	_
15	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	TNF	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	functional	_	ADJ	_	Degree=Pos	_	_	_	_
4	consequence	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	U937	_	NUM	_	Number=Sing	_	_	_	_
9	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	markedly	_	ADV	_	_	_	_	_	_
17	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
20	due	_	ADP	_	_	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	suppression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	E-selectin	_	ADJ	_	Number=Sing	_	_	_	_
29	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	related	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	cyclooxygenase	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	since	_	SCONJ	_	_	_	_	_	_
16	indomethacin	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	ineffective	_	ADJ	_	Degree=Pos	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	induction	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	E-selectin	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
25	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
26	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	TNF	_	PROPN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	thereby	_	ADV	_	_	_	_	_	_
35	providing	_	VERB	_	VerbForm=Ger	_	_	_	_
36	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	additional	_	ADJ	_	Degree=Pos	_	_	_	_
38	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
41	effects	_	NOUN	_	Number=Plur	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	aspirin	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012501	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	early	_	ADJ	_	Degree=Pos	_	_	_	_
5	growth	_	NOUN	_	Number=Sing	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	egr	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	X	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	immune	_	ADJ	_	Degree=Pos	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
5	early	_	ADJ	_	Degree=Pos	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	immune	_	ADJ	_	Number=Sing	_	_	_	_
12	system	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	critical	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	SCONJ	_	_	_	_	_	_
16	determining	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	ultimate	_	ADJ	_	Degree=Pos	_	_	_	_
19	outcome	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	exposure	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	antigen	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	importance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	many	_	ADJ	_	Degree=Pos	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	genes	_	NOUN	_	Number=Plur	_	_	_	_
8	relates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	products	_	NOUN	_	Number=Plur	_	_	_	_
16	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	dictating	_	ADJ	_	VerbForm=Ger	_	_	_	_
19	patterns	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	function	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	related	_	ADJ	_	Degree=Pos	_	_	_	_
28	genes	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	several	_	ADJ	_	Degree=Pos	_	_	_	_
4	systems	_	NOUN	_	Number=Plur	_	_	_	_
5	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
9	early	_	ADJ	_	Degree=Pos	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	egr	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	particular	_	ADJ	_	Degree=Pos	_	_	_	_
19	importance	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	immune	_	NOUN	_	Number=Sing	_	_	_	_
23	system	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	egr	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	highly	_	ADV	_	_	_	_	_	_
14	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
18	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
19	signals	_	NOUN	_	Number=Plur	_	_	_	_
20	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	antigen	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	immune	_	NOUN	_	Number=Sing	_	_	_	_
30	system	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	important	_	ADJ	_	Degree=Pos	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	egr	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	in	_	SCONJ	_	_	_	_	_	_
11	determining	_	VERB	_	VerbForm=Ger	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	pathway	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	precursors	_	NOUN	_	Number=Plur	_	_	_	_
19	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
21	recently	_	ADV	_	_	_	_	_	_
22	elaborated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	potential	_	ADJ	_	Degree=Pos	_	_	_	_
4	targets	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	zinc	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	finger	_	NOUN	_	Number=Sing	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	egr	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	CD44	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	tumor	_	NOUN	_	Number=Sing	_	_	_	_
33	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
34	factor	_	NOUN	_	Number=Sing	_	_	_	_
35	genes	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	egr	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	immune	_	ADJ	_	Degree=Pos	_	_	_	_
12	response	_	NOUN	_	Number=Sing	_	_	_	_
13	will	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	context	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	recent	_	ADJ	_	Degree=Pos	_	_	_	_
22	studies	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012506	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	T-cell	_	ADV	_	Number=Sing	_	_	_	_
2	functional	_	ADJ	_	Degree=Pos	_	_	_	_
3	regions	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	3	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	almost	_	ADV	_	_	_	_	_	_
15	exclusively	_	ADV	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	post	_	NOUN	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
13	level	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	treatment	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	phytohemaglutinin	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	PHA	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
19	ester	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	PMA	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	initiation	_	NOUN	_	Number=Sing	_	_	_	_
26	from	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	3	_	NUM	_	NumType=Card	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	define	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	regions	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	generated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	series	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	reporter	_	NOUN	_	Number=Sing	_	_	_	_
19	constructs	_	NOUN	_	Number=Plur	_	_	_	_
20	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	different	_	ADJ	_	Degree=Pos	_	_	_	_
22	regions	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	3	_	NUM	_	NumType=Card	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	5	_	NUM	_	NumType=Card	_	_	_	_
30	'	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	3	_	NUM	_	NumType=Card	_	_	_	_
33	'	_	PUNCT	_	_	_	_	_	_
34	flanking	_	NOUN	_	Number=Sing	_	_	_	_
35	sequences	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	positive	_	ADJ	_	Degree=Pos	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	negative	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	elements	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
12	5	_	NUM	_	NumType=Card	_	_	_	_
13	'	_	PUNCT	_	_	_	_	_	_
14	flanking	_	VERB	_	Number=Sing	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	promoter	_	NOUN	_	Number=Sing	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	-	_	SYM	_	_	_	_	_	_
6	173	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	-	_	SYM	_	_	_	_	_	_
9	60	_	NUM	_	NumType=Card	_	_	_	_
10	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	strongest	_	ADJ	_	Degree=Sup	_	_	_	_
13	activating	_	NOUN	_	Degree=Pos	_	_	_	_
14	elements	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	could	_	AUX	_	VerbForm=Fin	_	_	_	_
8	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
11	positive	_	ADJ	_	Degree=Pos	_	_	_	_
12	activator	_	NOUN	_	Number=Sing	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	function	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	CK	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1/CK	_	NUM	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	elements	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	present	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	many	_	ADJ	_	Degree=Pos	_	_	_	_
22	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
28	acted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	as	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	repressor	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	basal	_	ADJ	_	Degree=Pos	_	_	_	_
34	level	_	NOUN	_	Number=Sing	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	when	_	ADV	_	PronType=Int	_	_	_	_
37	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	upstream	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	but	_	CCONJ	_	_	_	_	_	_
44	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
45	also	_	ADV	_	_	_	_	_	_
46	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
47	by	_	ADP	_	_	_	_	_	_
48	PMA	_	NOUN	_	Number=Sing	_	_	_	_
49	/	_	PUNCT	_	_	_	_	_	_
50	PHA	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012512	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Negative	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
12	:	_	PUNCT	_	_	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	65	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kDa	_	NOUN	_	Number=Sing	_	_	_	_
19	plus	_	CCONJ	_	_	_	_	_	_
20	50	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kDa	_	NOUN	_	Number=Sing	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	dimer	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	can	_	AUX	_	VerbForm=Fin	_	_	_	_
5	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	reservoir	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	viral	_	ADJ	_	Degree=Pos	_	_	_	_
10	production	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	vivo	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
19	virus	_	NOUN	_	Number=Sing	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	HIV	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	_	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	can	_	AUX	_	VerbForm=Fin	_	_	_	_
29	be	_	AUX	_	VerbForm=Inf	_	_	_	_
30	either	_	CCONJ	_	_	_	_	_	_
31	latent	_	ADJ	_	Degree=Pos	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	productive	_	ADJ	_	Degree=Pos	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	differences	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
9	molecularly	_	ADV	_	_	_	_	_	_
10	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	THP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	there	_	PRON	_	_	_	_	_	_
12	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	absence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	binding	_	VERB	_	Number=Sing	_	_	_	_
20	complex	_	ADJ	_	Number=Sing	_	_	_	_
21	formation	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	HIV	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
30	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	markedly	_	ADV	_	_	_	_	_	_
33	less	_	ADV	_	Degree=Cmp	_	_	_	_
34	viral	_	ADJ	_	Degree=Pos	_	_	_	_
35	RNA	_	NOUN	_	Number=Sing	_	_	_	_
36	production	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	absence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	HIV	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
20	;	_	PUNCT	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	65	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kDa	_	NOUN	_	Number=Sing	_	_	_	_
25	plus	_	CCONJ	_	_	_	_	_	_
26	50	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kDa	_	NOUN	_	Number=Sing	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
34	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
35	preferentially	_	ADV	_	_	_	_	_	_
36	lost	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Adding	_	VERB	_	VerbForm=Ger	_	_	_	_
2	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	extracts	_	NOUN	_	Number=Plur	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	overcomes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
18	lack	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	extracts	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	sodium	_	NOUN	_	Number=Sing	_	_	_	_
11	deoxycholate	_	NOUN	_	Number=Sing	_	_	_	_
12	restored	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	ability	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	form	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	presence	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	activity	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	treatment	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	extracts	_	NOUN	_	Number=Plur	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
16	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	viral	_	ADJ	_	Degree=Pos	_	_	_	_
18	production	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	NF	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Antiserum	_	PROPN	_	Number=Sing	_	_	_	_
2	specific	_	ADJ	_	Degree=Pos	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	ADV	_	_	_	_	_	_
13	c-rel	_	ADV	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	antiserum	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	disrupted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
20	complex	_	ADJ	_	Number=Sing	_	_	_	_
21	formation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	both	_	CCONJ	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	complexes	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	needed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
15	viral	_	ADJ	_	Degree=Pos	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	65	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kDa	_	NOUN	_	Number=Sing	_	_	_	_
7	plus	_	CCONJ	_	_	_	_	_	_
8	50	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kDa	_	NOUN	_	Number=Sing	_	_	_	_
11	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	HIV	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
18	can	_	AUX	_	VerbForm=Fin	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	negatively	_	ADV	_	_	_	_	_	_
21	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	providing	_	VERB	_	VerbForm=Ger	_	_	_	_
26	one	_	NUM	_	NumType=Card	_	_	_	_
27	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
28	restricting	_	VERB	_	VerbForm=Ger	_	_	_	_
29	HIV	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012516	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cooperation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	sites	_	NOUN	_	Number=Plur	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	rel	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	4	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	up	_	ADP	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	regulation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	human	_	ADJ	_	Degree=Pos	_	_	_	_
26	IgE	_	PROPN	_	Number=Sing	_	_	_	_
27	germline	_	NOUN	_	Number=Sing	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Ig	_	ADJ	_	_	_	_	_	_
2	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
3	chain	_	NOUN	_	Number=Sing	_	_	_	_
4	class	_	NOUN	_	Number=Sing	_	_	_	_
5	switching	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	directed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
10	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	unrearranged	_	ADJ	_	Degree=Pos	_	_	_	_
14	CH	_	NOUN	_	Number=Sing	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Subsequently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	such	_	ADJ	_	Degree=Pos	_	_	_	_
4	primed	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	can	_	AUX	_	VerbForm=Fin	_	_	_	_
7	undergo	_	VERB	_	VerbForm=Inf	_	_	_	_
8	switch	_	NOUN	_	Number=Sing	_	_	_	_
9	recombination	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	express	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	new	_	ADJ	_	Degree=Pos	_	_	_	_
15	isotype	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	case	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	IgE	_	PROPN	_	Number=Sing	_	_	_	_
6	class	_	NOUN	_	Number=Sing	_	_	_	_
7	switching	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4	_	NUM	_	NumType=Card	_	_	_	_
12	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IgE	_	PROPN	_	Number=Sing	_	_	_	_
15	germline	_	NOUN	_	Number=Sing	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	SCONJ	_	_	_	_	_	_
18	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	interaction	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	4STAT	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
34	DNA	_	NOUN	_	Number=Sing	_	_	_	_
35	element	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
39	region	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	describes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	characterization	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	additional	_	ADJ	_	Degree=Pos	_	_	_	_
9	cis	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	acting	_	VERB	_	Number=Sing	_	_	_	_
12	elements	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	members	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	rel	_	NOUN	_	Number=Sing	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	family	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	4	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	independent	_	ADJ	_	Degree=Pos	_	_	_	_
34	fashion	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	nucleoprotein	_	NOUN	_	Number=Sing	_	_	_	_
9	complex	_	NOUN	_	Number=Sing	_	_	_	_
10	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	kappa	_	PROPN	_	Number=Sing	_	_	_	_
18	B1	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	classical	_	ADJ	_	Degree=Pos	_	_	_	_
23	p50/p65	_	NOUN	_	Number=Sing	_	_	_	_
24	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	complex	_	NOUN	_	Number=Sing	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
6	site	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B2	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	p50	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	relB	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	IgE	_	PROPN	_	Number=Sing	_	_	_	_
2	germline	_	NOUN	_	Number=Sing	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	reporter	_	NOUN	_	Number=Sing	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	constructs	_	NOUN	_	Number=Plur	_	_	_	_
7	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
8	point	_	NOUN	_	Number=Sing	_	_	_	_
9	mutations	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B2	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	largely	_	ADV	_	_	_	_	_	_
18	unresponsive	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	4	_	NUM	_	NumType=Card	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	transient	_	ADJ	_	Degree=Pos	_	_	_	_
26	transfection	_	NOUN	_	Number=Sing	_	_	_	_
27	experiments	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	while	_	SCONJ	_	_	_	_	_	_
30	plasmids	_	VERB	_	Number=Plur	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	similar	_	ADJ	_	Degree=Pos	_	_	_	_
33	mutations	_	NOUN	_	Number=Plur	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B1	_	PROPN	_	Number=Sing	_	_	_	_
39	site	_	NOUN	_	Number=Sing	_	_	_	_
40	responded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	to	_	ADP	_	_	_	_	_	_
42	cytokine	_	VERB	_	Number=Sing	_	_	_	_
43	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
44	better	_	ADV	_	Degree=Cmp	_	_	_	_
45	than	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	wild	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	type	_	NOUN	_	Number=Sing	_	_	_	_
50	promoter	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_

1	B2	_	ADJ	_	_	_	_	_	_
2	effect	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	presence	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	demonstrating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B2	_	NOUN	_	Number=Sing	_	_	_	_
20	motif	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
26	for	_	SCONJ	_	_	_	_	_	_
27	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
28	cytokine	_	VERB	_	Number=Sing	_	_	_	_
29	up	_	ADP	_	_	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	regulation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	combination	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	rel	_	NOUN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	element	_	NOUN	_	Number=Sing	_	_	_	_
20	conferred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	4	_	NUM	_	NumType=Card	_	_	_	_
24	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
28	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	while	_	SCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	individual	_	ADJ	_	Degree=Pos	_	_	_	_
34	sites	_	NOUN	_	Number=Plur	_	_	_	_
35	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	no	_	DET	_	_	_	_	_	_
37	effect	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	available	_	ADJ	_	Degree=Pos	_	_	_	_
3	data	_	NOUN	_	Number=Sing	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B2	_	PROPN	_	Number=Sing	_	_	_	_
2	nucleoprotein	_	NOUN	_	Number=Sing	_	_	_	_
3	complex	_	NOUN	_	Number=Sing	_	_	_	_
4	may	_	AUX	_	VerbForm=Fin	_	_	_	_
5	cooperate	_	VERB	_	VerbForm=Inf	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	DNA	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	bound	_	ADJ	_	Degree=Pos	_	_	_	_
10	STAT6	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	achieve	_	VERB	_	VerbForm=Inf	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	4	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	IgE	_	NOUN	_	Number=Sing	_	_	_	_
23	germline	_	NOUN	_	Degree=Pos	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012522	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Retinoic	_	ADJ	_	Number=Sing	_	_	_	_
2	acid	_	ADJ	_	Number=Sing	_	_	_	_
3	inhibits	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	CD40	_	PROPN	_	Number=Sing	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_
6	interleukin-4-mediated	_	ADJ	_	Degree=Pos	_	_	_	_

1	IgE	_	NOUN	_	Number=Sing	_	_	_	_
2	production	_	NOUN	_	Number=Sing	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vitro	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	elucidate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	retinoic	_	PROPN	_	Number=Sing	_	_	_	_
7	acid	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	RA	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	anti-CD40	_	NUM	_	Number=Sing	_	_	_	_
13	+	_	SYM	_	_	_	_	_	_
14	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	4	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	effect	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	10	_	NUM	_	NumType=Card	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	-	_	SYM	_	_	_	_	_	_
35	12	_	NUM	_	NumType=Card	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	10	_	NUM	_	NumType=Card	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	-	_	SYM	_	_	_	_	_	_
41	6	_	NUM	_	NumType=Card	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	mol	_	NOUN	_	Number=Sing	_	_	_	_
44	/	_	PUNCT	_	_	_	_	_	_
45	L	_	PROPN	_	Number=Sing	_	_	_	_
46	RA	_	PROPN	_	Number=Sing	_	_	_	_
47	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
48	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	anti-CD40	_	NOUN	_	Number=Sing	_	_	_	_
51	(	_	PUNCT	_	_	_	_	_	_
52	1	_	NUM	_	NumType=Card	_	_	_	_
53	microgram	_	NOUN	_	Number=Sing	_	_	_	_
54	/	_	PUNCT	_	_	_	_	_	_
55	mL	_	NOUN	_	Number=Sing	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	+	_	SYM	_	_	_	_	_	_
58	IL	_	PROPN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	4	_	NUM	_	NumType=Card	_	_	_	_
61	(	_	PUNCT	_	_	_	_	_	_
62	5	_	NUM	_	NumType=Card	_	_	_	_
63	ng	_	NOUN	_	Number=Sing	_	_	_	_
64	/	_	PUNCT	_	_	_	_	_	_
65	mL	_	NOUN	_	Number=Sing	_	_	_	_
66	)	_	PUNCT	_	_	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	mediated	_	VERB	_	Degree=Pos	_	_	_	_
69	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
70	and	_	CCONJ	_	_	_	_	_	_
71	Ig	_	NOUN	_	Degree=Pos	_	_	_	_
72	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
73	by	_	ADP	_	_	_	_	_	_
74	human	_	ADJ	_	Degree=Pos	_	_	_	_
75	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
76	blood	_	NOUN	_	Number=Sing	_	_	_	_
77	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
78	cells	_	NOUN	_	Number=Plur	_	_	_	_
79	(	_	PUNCT	_	_	_	_	_	_
80	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
81	)	_	PUNCT	_	_	_	_	_	_
82	and	_	CCONJ	_	_	_	_	_	_
83	B	_	ADJ	_	Degree=Pos	_	_	_	_
84	cells	_	NOUN	_	Number=Plur	_	_	_	_
85	in	_	ADP	_	_	_	_	_	_
86	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
87	donors	_	NOUN	_	Number=Plur	_	_	_	_
88	.	_	PUNCT	_	_	_	_	_	_

1	Anti-CD40	_	PROPN	_	Number=Sing	_	_	_	_
2	+	_	SYM	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	4	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	mediated	_	VERB	_	Degree=Pos	_	_	_	_
8	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	RA	_	PROPN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	dose	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	manner	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
27	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	62	_	NUM	_	NumType=Card	_	_	_	_
30	%	_	SYM	_	Number=Sing	_	_	_	_
31	+/-	_	SYM	_	_	_	_	_	_
32	5	_	NUM	_	NumType=Card	_	_	_	_
33	%	_	SYM	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	55	_	NUM	_	NumType=Card	_	_	_	_
38	%	_	SYM	_	Number=Sing	_	_	_	_
39	+/-	_	SYM	_	_	_	_	_	_
40	4.4	_	NUM	_	NumType=Card	_	_	_	_
41	%	_	SYM	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	B	_	ADJ	_	Number=Sing	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	by	_	ADP	_	_	_	_	_	_
46	all	_	DET	_	_	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	trans	_	NOUN	_	Number=Sing	_	_	_	_
49	RA	_	NOUN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	58	_	NUM	_	NumType=Card	_	_	_	_
53	%	_	SYM	_	Number=Sing	_	_	_	_
54	+/-	_	SYM	_	_	_	_	_	_
55	6.7	_	NUM	_	NumType=Card	_	_	_	_
56	%	_	SYM	_	Number=Sing	_	_	_	_
57	and	_	CCONJ	_	_	_	_	_	_
58	51	_	NUM	_	NumType=Card	_	_	_	_
59	%	_	SYM	_	Number=Sing	_	_	_	_
60	+/-	_	SYM	_	_	_	_	_	_
61	4.7	_	NUM	_	NumType=Card	_	_	_	_
62	%	_	SYM	_	Number=Sing	_	_	_	_
63	,	_	PUNCT	_	_	_	_	_	_
64	respectively	_	ADV	_	_	_	_	_	_
65	by	_	ADP	_	_	_	_	_	_
66	13	_	NUM	_	NumType=Card	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	cis	_	NOUN	_	Number=Sing	_	_	_	_
69	RA	_	NOUN	_	Number=Sing	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	IgE	_	PROPN	_	Number=Sing	_	_	_	_
2	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	even	_	ADV	_	_	_	_	_	_
5	more	_	ADV	_	_	_	_	_	_
6	markedly	_	ADV	_	_	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	RA	_	PROPN	_	Number=Sing	_	_	_	_
10	starting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	>	_	PUNCT	_	_	_	_	_	_
15	10	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	14	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	mol	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	L	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	B	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	>	_	PUNCT	_	_	_	_	_	_
28	10	_	NUM	_	NumType=Card	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	-	_	SYM	_	_	_	_	_	_
31	10	_	NUM	_	NumType=Card	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	mol	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	L	_	NOUN	_	Number=Sing	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Maximal	_	ADJ	_	Degree=Pos	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	IgE	_	NOUN	_	Number=Sing	_	_	_	_
5	production	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	B	_	ADJ	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	10	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	8	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	mol	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	L	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	all	_	DET	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	trans	_	NOUN	_	Number=Sing	_	_	_	_
23	RA	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	94	_	NUM	_	NumType=Card	_	_	_	_
26	%	_	SYM	_	Number=Sing	_	_	_	_
27	+/-	_	SYM	_	_	_	_	_	_
28	1.8	_	NUM	_	NumType=Card	_	_	_	_
29	%	_	SYM	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	96	_	NUM	_	NumType=Card	_	_	_	_
33	%	_	SYM	_	Number=Sing	_	_	_	_
34	+/-	_	SYM	_	_	_	_	_	_
35	3.2	_	NUM	_	NumType=Card	_	_	_	_
36	%	_	SYM	_	Number=Sing	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	13	_	NUM	_	NumType=Card	_	_	_	_
39	-	_	SYM	_	_	_	_	_	_
40	cis	_	NOUN	_	Number=Sing	_	_	_	_
41	RA	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Low	_	ADJ	_	Degree=Pos	_	_	_	_
2	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	RA	_	PROPN	_	Number=Sing	_	_	_	_
5	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
6	IgE	_	PROPN	_	Number=Sing	_	_	_	_
7	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	10	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	mol	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	L	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	neither	_	CCONJ	_	_	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
24	nor	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	production	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	IgA	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	IgG	_	PROPN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	IgM	_	PROPN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Elucidation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	involved	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IgE	_	PROPN	_	Number=Sing	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
15	germline	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	RA	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	whereas	_	SCONJ	_	_	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	interferon	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	gamma	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	IFN	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	gamma	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	presence	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	RA	_	PROPN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	whether	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	RA	_	PROPN	_	Number=Sing	_	_	_	_
6	effect	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	RA	_	PROPN	_	Number=Sing	_	_	_	_
11	receptors	_	NOUN	_	Number=Plur	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	gamma	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
24	acid	_	NOUN	_	Number=Sing	_	_	_	_
25	receptors	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	RAR	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	reverse	_	NOUN	_	Number=Sing	_	_	_	_
33	transcriptase	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
36	chain	_	NOUN	_	Number=Sing	_	_	_	_
37	reaction	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	RT	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	PCR	_	NOUN	_	Number=Sing	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	peripheral	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	express	_	VERB	_	Degree=Pos	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	RA	_	PROPN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	beta	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	gamma	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	retinoids	_	NOUN	_	Number=Plur	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	different	_	ADJ	_	Degree=Pos	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	specificity	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	CD336	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	CD437	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	CD2019	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	CD367	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	dose	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
21	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	IgE	_	ADJ	_	Number=Sing	_	_	_	_
24	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	all	_	DET	_	_	_	_	_	_
29	four	_	NUM	_	NumType=Card	_	_	_	_
30	derivates	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	but	_	CCONJ	_	_	_	_	_	_
33	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
34	most	_	ADV	_	_	_	_	_	_
35	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	RA	_	NOUN	_	Number=Sing	_	_	_	_
39	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	alpha	_	NOUN	_	Number=Sing	_	_	_	_
42	receptor	_	NOUN	_	Number=Sing	_	_	_	_
43	with	_	ADP	_	_	_	_	_	_
44	high	_	ADJ	_	Degree=Pos	_	_	_	_
45	specificity	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	RA	_	PROPN	_	Number=Sing	_	_	_	_
9	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	IgE	_	PROPN	_	Number=Sing	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	anti-CD40	_	NOUN	_	Number=Sing	_	_	_	_
14	+	_	SYM	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	4	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	vitro	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1998	_	NUM	_	NumType=Card	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	American	_	PROPN	_	Degree=Pos	_	_	_	_
6	Society	_	PROPN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Hematology	_	PROPN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012523	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interferons	_	PROPN	_	Number=Plur	_	_	_	_
2	inhibit	_	VERB	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	STAT6	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
8	4	_	NUM	_	NumType=Card	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
14	SOCS	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Interferons	_	PROPN	_	Number=Plur	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IFNs	_	PROPN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	inhibit	_	NOUN	_	Number=Sing	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	IFNs	_	PROPN	_	Number=Plur	_	_	_	_
8	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	activates	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	SCONJ	_	_	_	_	_	_
8	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
10	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	homodimerization	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	translocation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	latent	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	STAT6	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	signal	_	NOUN	_	Number=Sing	_	_	_	_
26	transducer	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	activator	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	transcription	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	6	_	NUM	_	NumType=Card	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	STAT6	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
4	elements	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	characteristically	_	ADV	_	_	_	_	_	_
7	present	_	ADJ	_	Degree=Pos	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	promoters	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	4	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	essential	_	ADJ	_	Degree=Pos	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	4	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	ability	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	type	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	II	_	NUM	_	NumType=Card	_	_	_	_
25	IFNs	_	NOUN	_	Number=Plur	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	STAT6	_	NOUN	_	Number=Sing	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	4	_	NUM	_	NumType=Card	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	primary	_	ADJ	_	Degree=Pos	_	_	_	_
37	human	_	ADJ	_	Degree=Pos	_	_	_	_
38	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	IFN	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
24	colony	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
32	colony	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	6	_	NUM	_	NumType=Card	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	or	_	CCONJ	_	_	_	_	_	_
42	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
43	growth	_	NOUN	_	Number=Sing	_	_	_	_
44	factor	_	NOUN	_	Number=Sing	_	_	_	_
45	beta	_	NOUN	_	Number=Sing	_	_	_	_
46	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	activation	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	STAT6	_	NOUN	_	Number=Sing	_	_	_	_
50	by	_	ADP	_	_	_	_	_	_
51	IL	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	4	_	NUM	_	NumType=Card	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
8	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	translocation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	evident	_	ADJ	_	Degree=Pos	_	_	_	_
18	unless	_	SCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	preincubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	IFN	_	PROPN	_	Number=Sing	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	at	_	ADV	_	_	_	_	_	_
27	least	_	ADV	_	Degree=Sup	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	hr	_	NOUN	_	Number=Sing	_	_	_	_
30	before	_	ADP	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	4	_	NUM	_	NumType=Card	_	_	_	_
34	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	could	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	cotreatment	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	actinomycin	_	NOUN	_	Number=Sing	_	_	_	_
13	D	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	temporally	_	ADV	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	JAK	_	PROPN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	STAT	_	NOUN	_	Number=Sing	_	_	_	_
24	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	SOCS	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Forced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	SOCS	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	RAW264	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	markedly	_	ADV	_	_	_	_	_	_
16	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	trans	_	NOUN	_	Number=Plur	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
27	reporter	_	NOUN	_	Number=Sing	_	_	_	_
28	as	_	ADV	_	_	_	_	_	_
29	well	_	ADV	_	Degree=Pos	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	6	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	IFN	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	gamma	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	reporter	_	NOUN	_	Number=Sing	_	_	_	_
42	gene	_	NOUN	_	Number=Sing	_	_	_	_
43	activity	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IFNs	_	PROPN	_	Number=Sing	_	_	_	_
6	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	4	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	at	_	ADV	_	_	_	_	_	_
23	least	_	ADV	_	Degree=Sup	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	part	_	ADJ	_	Degree=Pos	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	by	_	SCONJ	_	_	_	_	_	_
28	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	SOCS	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_
35	Document	_	NOUN	_	Number=Sing	_	_	_	_
36	0030012536	_	NUM	_	NumType=Card	_	_	_	_
37	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IkB	_	PROPN	_	Number=Sing	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	PKC	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	Ca	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	+)-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	signal	_	NOUN	_	Number=Sing	_	_	_	_
16	transduction	_	NOUN	_	Number=Sing	_	_	_	_
17	pathways	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Ca	_	PROPN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	+)-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
8	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	target	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	FK506	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	CsA	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	synergizes	_	VERB	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	PKC	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	T	_	PROPN	_	Number=Sing	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	lines	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	whether	_	SCONJ	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	synergy	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	present	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	other	_	ADJ	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	types	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	s	_	X	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
22	two	_	NUM	_	NumType=Card	_	_	_	_
23	pathways	_	NOUN	_	Number=Plur	_	_	_	_
24	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	synergy	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	present	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	other	_	ADJ	_	Degree=Pos	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	types	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	line	_	NOUN	_	Number=Sing	_	_	_	_
16	U937	_	NOUN	_	Number=Sing	_	_	_	_
17	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B.	_	PROPN	_	Number=Sing	_	_	_	_
27	Having	_	AUX	_	VerbForm=Ger	_	_	_	_
28	previously	_	ADV	_	_	_	_	_	_
29	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	that	_	SCONJ	_	_	_	_	_	_
31	Ca	_	PROPN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	+)-	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	PKC	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
39	pathways	_	NOUN	_	Number=Plur	_	_	_	_
40	synergize	_	VERB	_	Number=Sing	_	_	_	_
41	by	_	SCONJ	_	_	_	_	_	_
42	accelerating	_	VERB	_	VerbForm=Ger	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	degradation	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	IkB	_	PROPN	_	Number=Sing	_	_	_	_
47	alpha	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
50	focused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
51	on	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	regulation	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	IkB	_	PROPN	_	Number=Sing	_	_	_	_
56	alpha	_	NOUN	_	Number=Sing	_	_	_	_
57	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	PKC	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	pathways	_	NOUN	_	Number=Plur	_	_	_	_
6	sequentially	_	ADV	_	_	_	_	_	_
7	result	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	incomplete	_	ADJ	_	Degree=Pos	_	_	_	_
15	degradation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	IkB	_	NOUN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	T	_	PROPN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	lines	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	co-activation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	Ca	_	PROPN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	+)-	_	SYM	_	_	_	_	_	_
30	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
31	pathways	_	NOUN	_	Number=Plur	_	_	_	_
32	accelerates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	rate	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	IkB	_	NOUN	_	Number=Sing	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	results	_	NOUN	_	Number=Plur	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
43	complete	_	ADJ	_	Degree=Pos	_	_	_	_
44	degradation	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Ca	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	+)-	_	SYM	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	pathways	_	NOUN	_	Number=Plur	_	_	_	_
9	alone	_	ADV	_	_	_	_	_	_
10	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	result	_	VERB	_	VerbForm=Inf	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	degradation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	IkB	_	PROPN	_	Number=Sing	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
25	T	_	PROPN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	U937	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	selective	_	ADJ	_	Degree=Pos	_	_	_	_
8	PKC	_	PROPN	_	Number=Sing	_	_	_	_
9	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
10	GF109203X	_	PROPN	_	Number=Sing	_	_	_	_
11	abrogates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	PMA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	IkB	_	NOUN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	degradation	_	NOUN	_	Number=Sing	_	_	_	_
21	irrespective	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	Ca	_	PROPN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	+)-	_	SYM	_	_	_	_	_	_
29	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
30	pathways	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	but	_	CCONJ	_	_	_	_	_	_
33	not	_	ADV	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	degradation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	IkB	_	PROPN	_	Number=Sing	_	_	_	_
40	alpha	_	NOUN	_	Number=Sing	_	_	_	_
41	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	by	_	ADP	_	_	_	_	_	_
43	TNF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	alpha	_	PROPN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
48	PKC	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	independent	_	ADJ	_	Degree=Pos	_	_	_	_
51	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Contrary	_	ADJ	_	Degree=Pos	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	interaction	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	PKC	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	Ca	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	+)-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	pathways	_	NOUN	_	Number=Plur	_	_	_	_
14	synergize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	level	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	IkB	_	PROPN	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	but	_	CCONJ	_	_	_	_	_	_
29	at	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	level	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	degradation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Ca	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	+)-	_	SYM	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	pathways	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	including	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
15	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	regulation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappa	_	NOUN	_	Number=Sing	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	specific	_	ADJ	_	Degree=Pos	_	_	_	_
30	fashion	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	synergize	_	NOUN	_	Number=Sing	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	PKC	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	independent	_	ADJ	_	Degree=Pos	_	_	_	_
40	pathways	_	NOUN	_	Number=Plur	_	_	_	_
41	at	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	level	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	IkB	_	PROPN	_	Number=Sing	_	_	_	_
46	alpha	_	NOUN	_	Number=Sing	_	_	_	_
47	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	degradation	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012539	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	C	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
8	effector	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	aim	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	present	_	ADJ	_	Degree=Pos	_	_	_	_
6	study	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	kinase	_	NOUN	_	Number=Sing	_	_	_	_
15	C	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	PKC	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	downstream	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	in	_	SCONJ	_	_	_	_	_	_
25	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
26	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	_	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	PKC	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	effector	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Data	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	presented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	using	_	VERB	_	VerbForm=Ger	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	potent	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	selective	_	ADJ	_	Degree=Pos	_	_	_	_
10	PKC	_	NOUN	_	Number=Sing	_	_	_	_
11	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
12	Ro	_	NOUN	_	Number=Sing	_	_	_	_
13	31-8425	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	transient	_	ADJ	_	Degree=Pos	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	constitutively	_	ADV	_	_	_	_	_	_
20	active	_	ADJ	_	Degree=Pos	_	_	_	_
21	ras	_	NOUN	_	Number=Sing	_	_	_	_
22	mutant	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	clearly	_	ADV	_	_	_	_	_	_
26	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	PKC	_	PROPN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	not	_	PART	_	_	_	_	_	_
31	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	p21ras	_	NOUN	_	Number=Plur	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	induction	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	AT	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	AP	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
46	activity	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	expression	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	IL	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	2	_	NUM	_	NumType=Card	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	human	_	ADJ	_	Degree=Pos	_	_	_	_
57	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
58	T	_	NOUN	_	Number=Sing	_	_	_	_
59	cells	_	NOUN	_	Number=Plur	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Reporter	_	NOUN	_	Number=Sing	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	signaling	_	NOUN	_	Number=Sing	_	_	_	_
3	pathways	_	NOUN	_	Number=Plur	_	_	_	_
4	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
5	PKC	_	PROPN	_	Number=Sing	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	calcium	_	NOUN	_	Number=Sing	_	_	_	_
9	mobilization	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	ras	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	combine	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
18	components	_	NOUN	_	Number=Plur	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	production	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	during	_	ADP	_	_	_	_	_	_
26	T	_	NOUN	_	Number=Sing	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012541	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Involvement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	pathways	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	8	_	NUM	_	NumType=Card	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	polymorphonuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	Mycoplasma	_	PROPN	_	Number=Sing	_	_	_	_
25	fermentans	_	NOUN	_	Number=Plur	_	_	_	_
26	membrane	_	NOUN	_	Number=Sing	_	_	_	_
27	lipoproteins	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-8	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	8	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	belongs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	CXC	_	PROPN	_	Number=Sing	_	_	_	_
19	subfamily	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	wide	_	ADJ	_	Degree=Pos	_	_	_	_
26	variety	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	including	_	VERB	_	VerbForm=Ger	_	_	_	_
32	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	polymorphonuclear	_	ADJ	_	Degree=Pos	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	PMN	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	8	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	secreted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	notably	_	ADV	_	_	_	_	_	_
13	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
14	products	_	NOUN	_	Number=Plur	_	_	_	_
15	such	_	ADJ	_	Degree=Pos	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	LPS	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	little	_	ADV	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	about	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	which	_	PRON	_	PronType=Rel	_	_	_	_
31	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
32	agents	_	NOUN	_	Number=Plur	_	_	_	_
33	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	8	_	NUM	_	NumType=Card	_	_	_	_
37	induction	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	Mycoplasma	_	PROPN	_	Number=Sing	_	_	_	_
9	fermentans	_	VERB	_	Number=Plur	_	_	_	_
10	lipid	_	VERB	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	membrane	_	NOUN	_	Number=Sing	_	_	_	_
14	proteins	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	LAMPf	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	production	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	high	_	ADJ	_	Degree=Pos	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	8	_	NUM	_	NumType=Card	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	THP	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	human	_	ADJ	_	Degree=Pos	_	_	_	_
34	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	PMN	_	NOUN	_	Number=Sing	_	_	_	_
39	at	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	same	_	ADJ	_	Degree=Pos	_	_	_	_
42	extent	_	NOUN	_	Number=Sing	_	_	_	_
43	as	_	ADP	_	_	_	_	_	_
44	LPS	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	either	_	CCONJ	_	_	_	_	_	_
12	LPS	_	NOUN	_	Number=Plur	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	LAMPf	_	NOUN	_	Number=Sing	_	_	_	_
15	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	series	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	common	_	ADJ	_	Degree=Pos	_	_	_	_
21	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
22	signaling	_	NOUN	_	Number=Sing	_	_	_	_
23	events	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	including	_	VERB	_	VerbForm=Ger	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
31	kinase	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	mitogen	_	ADJ	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	protein	_	NOUN	_	Number=Sing	_	_	_	_
38	kinase	_	NOUN	_	Number=Sing	_	_	_	_
39	cascades	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	PD	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	98059	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	SB203580	_	NUM	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	potent	_	ADJ	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	selective	_	ADJ	_	Degree=Pos	_	_	_	_
13	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	MEK1	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	kinase	_	NOUN	_	Number=Sing	_	_	_	_
19	upstream	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	ERK1	_	PROPN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	p38	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	respectively	_	ADV	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
31	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	that	_	SCONJ	_	_	_	_	_	_
34	both	_	CCONJ	_	_	_	_	_	_
35	ERK1	_	PROPN	_	Number=Sing	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	p38	_	NOUN	_	Number=Sing	_	_	_	_
40	cascades	_	NOUN	_	Number=Plur	_	_	_	_
41	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	key	_	ADJ	_	Degree=Pos	_	_	_	_
44	role	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	production	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	IL	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	8	_	NUM	_	NumType=Card	_	_	_	_
52	by	_	ADP	_	_	_	_	_	_
53	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
54	and	_	CCONJ	_	_	_	_	_	_
55	PMN	_	NOUN	_	Number=Sing	_	_	_	_
56	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
57	with	_	ADP	_	_	_	_	_	_
58	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
59	fractions	_	NOUN	_	Number=Plur	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012543	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	10	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
6	growth	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	beta	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	polymorphisms	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	allergies	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	asthma	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-10	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	10	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
9	growth	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	TGF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	beta	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	B	_	NOUN	_	Degree=Pos	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	IgE	_	NOUN	_	Number=Sing	_	_	_	_
26	production	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	mast	_	ADJ	_	Degree=Pos	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
35	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	therefore	_	ADV	_	_	_	_	_	_
5	candidate	_	NOUN	_	Number=Sing	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	could	_	AUX	_	VerbForm=Fin	_	_	_	_
9	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	development	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	asthma	_	NOUN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	allergies	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	polymorphic	_	ADJ	_	Degree=Pos	_	_	_	_
7	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
8	within	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	10	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	TGF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	beta	_	NOUN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	promoters	_	NOUN	_	Number=Plur	_	_	_	_
19	would	_	AUX	_	VerbForm=Fin	_	_	_	_
20	link	_	VERB	_	VerbForm=Inf	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	allergies	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	asthma	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	families	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	asthmatic	_	ADJ	_	Degree=Pos	_	_	_	_
8	proband	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	base	_	NOUN	_	Number=Sing	_	_	_	_
13	exchanges	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	single	_	ADJ	_	Degree=Pos	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	stranded	_	VERB	_	Degree=Pos	_	_	_	_
18	conformational	_	ADJ	_	Degree=Pos	_	_	_	_
19	polymorphism	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	SSCP	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	presence	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	polymorphism	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	promoter	_	ADJ	_	Number=Sing	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	10	_	NUM	_	NumType=Card	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	four	_	NUM	_	NumType=Card	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	TGF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	beta	_	NOUN	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	promoters	_	NOUN	_	Number=Plur	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	3	_	NUM	_	NumType=Card	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	TGF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	beta1	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	TGF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	beta2	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	10	_	NUM	_	NumType=Card	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	polymorphism	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	C	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	exchange	_	NOUN	_	Number=Sing	_	_	_	_
15	571	_	NUM	_	NumType=Card	_	_	_	_
16	base	_	NOUN	_	Number=Sing	_	_	_	_
17	pairs	_	NOUN	_	Number=Plur	_	_	_	_
18	upstream	_	NOUN	_	Number=Sing	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	translation	_	NOUN	_	Number=Sing	_	_	_	_
22	start	_	NOUN	_	Number=Sing	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	present	_	ADJ	_	Degree=Pos	_	_	_	_
27	between	_	ADP	_	_	_	_	_	_
28	consensus	_	NOUN	_	Number=Sing	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	sequences	_	NOUN	_	Number=Plur	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	total	_	ADJ	_	Degree=Pos	_	_	_	_
36	serum	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	polymorphism	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	total	_	ADJ	_	Degree=Pos	_	_	_	_
8	serum	_	NOUN	_	Number=Sing	_	_	_	_
9	IgE	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	subjects	_	NOUN	_	Number=Plur	_	_	_	_
12	heterozygotic	_	NOUN	_	Degree=Pos	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	homozygotic	_	ADJ	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	base	_	NOUN	_	Number=Sing	_	_	_	_
18	exchange	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	p	_	NOUN	_	Number=Sing	_	_	_	_
21	<	_	PUNCT	_	_	_	_	_	_
22	0.009	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	base	_	NOUN	_	Number=Sing	_	_	_	_
3	exchange	_	NOUN	_	Number=Sing	_	_	_	_
4	at	_	ADP	_	_	_	_	_	_
5	-	_	SYM	_	_	_	_	_	_
6	509	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	initiation	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	TGF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	beta	_	NOUN	_	Number=Sing	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	also	_	ADV	_	_	_	_	_	_
21	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	total	_	ADJ	_	Degree=Pos	_	_	_	_
25	IgE	_	PROPN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	p	_	NOUN	_	Number=Sing	_	_	_	_
28	<	_	PUNCT	_	_	_	_	_	_
29	0.01	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	polymorphism	_	NOUN	_	Number=Sing	_	_	_	_
3	represented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	C	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	-T	_	PUNCT	_	Number=Sing	_	_	_	_
9	base	_	NOUN	_	Number=Sing	_	_	_	_
10	exchange	_	NOUN	_	Number=Sing	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	YY1	_	PROPN	_	Number=Sing	_	_	_	_
15	consensus	_	NOUN	_	Number=Sing	_	_	_	_
16	sequence	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	present	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	region	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	negative	_	ADJ	_	Degree=Pos	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	regulation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012546	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NFAT4	_	PROPN	_	Number=Sing	_	_	_	_
5	opposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	JNK	_	PROPN	_	Number=Sing	_	_	_	_
9	signal	_	NOUN	_	Number=Sing	_	_	_	_
10	transduction	_	NOUN	_	Number=Sing	_	_	_	_
11	pathway	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	group	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	retained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	quiescent	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	NFAT	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	part	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	induced	_	VERB	_	VerbForm=Ger	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	import	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	process	_	NOUN	_	Number=Sing	_	_	_	_
3	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	calcium	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
10	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
14	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	c-Jun	_	NOUN	_	Number=Sing	_	_	_	_
3	amino	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	terminal	_	NOUN	_	Number=Sing	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	JNK	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	phosphorylates	_	VERB	_	Number=Sing	_	_	_	_
11	NFAT4	_	NOUN	_	Number=Sing	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	two	_	NUM	_	NumType=Card	_	_	_	_
14	sites	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Mutational	_	ADJ	_	Degree=Pos	_	_	_	_
2	removal	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	JNK	_	PROPN	_	Number=Sing	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	localization	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NFAT4	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	JNK	_	PROPN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	exclusion	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NFAT4	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NFAT4	_	PROPN	_	Number=Sing	_	_	_	_
10	promoted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	opposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	JNK	_	PROPN	_	Number=Sing	_	_	_	_
18	signal	_	NOUN	_	Number=Sing	_	_	_	_
19	transduction	_	NOUN	_	Number=Sing	_	_	_	_
20	pathway	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012547	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	8	_	NUM	_	NumType=Card	_	_	_	_
7	production	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	eosinophil	_	ADJ	_	Number=Sing	_	_	_	_
10	granule	_	NOUN	_	Number=Sing	_	_	_	_
11	major	_	ADJ	_	Degree=Pos	_	_	_	_
12	basic	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	evaluated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	ability	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	eosinophil	_	NOUN	_	Number=Sing	_	_	_	_
7	granule	_	NOUN	_	Number=Sing	_	_	_	_
8	major	_	ADJ	_	Degree=Pos	_	_	_	_
9	basic	_	ADJ	_	Degree=Pos	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	MBP	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	8	_	NUM	_	NumType=Card	_	_	_	_
22	production	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	MBP	_	NOUN	_	Number=Sing	_	_	_	_
2	over	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	concentration	_	NOUN	_	Number=Sing	_	_	_	_
5	range	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	0.1	_	NUM	_	NumType=Card	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	microM	_	NOUN	_	Number=Sing	_	_	_	_
11	stimulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	release	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	up	_	ADP	_	_	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	approximately	_	ADV	_	_	_	_	_	_
18	8	_	NUM	_	NumType=Card	_	_	_	_
19	ng	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	ml	_	NOUN	_	Number=Sing	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	8	_	NUM	_	NumType=Card	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Incubation	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	microM	_	NOUN	_	Number=Sing	_	_	_	_
5	MBP	_	NOUN	_	Number=Sing	_	_	_	_
6	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	PRON	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	after	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	h	_	NOUN	_	Number=Sing	_	_	_	_
13	lag	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	level	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	8	_	NUM	_	NumType=Card	_	_	_	_
21	release	_	NOUN	_	Number=Sing	_	_	_	_
22	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	time	_	NOUN	_	Number=Sing	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	approximately	_	ADV	_	_	_	_	_	_
27	10	_	NUM	_	NumType=Card	_	_	_	_
28	h	_	NOUN	_	NumType=Card	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	microM	_	NOUN	_	Number=Sing	_	_	_	_
5	concentration	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	eosinophil	_	ADJ	_	Number=Sing	_	_	_	_
8	cationic	_	ADJ	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	eosinophil	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	neurotoxin	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	eosinophil	_	ADJ	_	Number=Sing	_	_	_	_
18	peroxidase	_	NOUN	_	Number=Sing	_	_	_	_
19	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	significant	_	ADJ	_	Degree=Pos	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	8	_	NUM	_	NumType=Card	_	_	_	_
28	production	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	MBP	_	NOUN	_	Number=Sing	_	_	_	_
2	stimulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	fold	_	NOUN	_	Number=Sing	_	_	_	_
6	increases	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	8	_	NUM	_	NumType=Card	_	_	_	_
11	messenger	_	NOUN	_	Number=Sing	_	_	_	_
12	RNA	_	PROPN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	after	_	ADP	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	h	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	incubation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	actinomycin	_	NOUN	_	Number=Sing	_	_	_	_
31	D.	_	PROPN	_	Number=Sing	_	_	_	_
32	However	_	ADV	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	MBP	_	NOUN	_	Number=Sing	_	_	_	_
37	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	not	_	PART	_	_	_	_	_	_
39	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
40	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	increase	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	binding	_	NOUN	_	Number=Sing	_	_	_	_
45	activity	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
48	factor	_	NOUN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	NF	_	PROPN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
54	or	_	CCONJ	_	_	_	_	_	_
55	activator	_	NOUN	_	Number=Sing	_	_	_	_
56	protein	_	NOUN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	1	_	NUM	_	NumType=Card	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	No	_	DET	_	_	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	same	_	ADJ	_	Degree=Pos	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	extracts	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	MBP	_	NOUN	_	Number=Sing	_	_	_	_
7	prolonged	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	stability	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	8	_	NUM	_	NumType=Card	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	MBP	_	NOUN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	transient	_	ADJ	_	Degree=Pos	_	_	_	_
5	increases	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
10	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	MIP	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	MIP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1beta	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	release	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	either	_	CCONJ	_	_	_	_	_	_
30	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	MBP	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	selective	_	ADJ	_	Degree=Pos	_	_	_	_
8	among	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	eosinophil	_	ADJ	_	Number=Sing	_	_	_	_
11	granule	_	NOUN	_	Number=Sing	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	neutrophil	_	ADJ	_	Number=Sing	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	8	_	NUM	_	NumType=Card	_	_	_	_
21	release	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	further	_	ADV	_	Degree=Cmp	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
27	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	neutrophil	_	ADJ	_	Number=Sing	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	8	_	NUM	_	NumType=Card	_	_	_	_
33	release	_	NOUN	_	Number=Sing	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	MBP	_	PROPN	_	Number=Sing	_	_	_	_
36	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	both	_	CCONJ	_	_	_	_	_	_
38	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	posttranscriptional	_	ADJ	_	Degree=Pos	_	_	_	_
41	regulation	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	postulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	MBP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	release	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	8	_	NUM	_	NumType=Card	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	pathophysiology	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	acute	_	ADJ	_	Degree=Pos	_	_	_	_
21	asthma	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	other	_	ADJ	_	Degree=Pos	_	_	_	_
24	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	lung	_	NOUN	_	Number=Sing	_	_	_	_
26	diseases	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012555	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	NFATc	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	natural	_	ADJ	_	Degree=Pos	_	_	_	_
20	killer	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	:	_	PUNCT	_	_	_	_	_	_
23	regulation	_	NOUN	_	Number=Sing	_	_	_	_
24	upon	_	ADP	_	_	_	_	_	_
25	CD16	_	PROPN	_	Number=Sing	_	_	_	_
26	ligand	_	NOUN	_	Number=Sing	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	putative	_	ADJ	_	Degree=Pos	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	couple	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	signal	_	NOUN	_	Number=Sing	_	_	_	_
8	transduction	_	NOUN	_	Number=Sing	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	surface	_	NOUN	_	Number=Sing	_	_	_	_
11	receptors	_	NOUN	_	Number=Plur	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
17	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	natural	_	ADJ	_	Degree=Pos	_	_	_	_
20	killer	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	NK	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
28	elucidated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
18	A	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	CsA	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	several	_	ADJ	_	Degree=Pos	_	_	_	_
31	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	mediates	_	VERB	_	Degree=Pos	_	_	_	_
34	CD16	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	cytokine	_	ADJ	_	Degree=Pos	_	_	_	_
40	genes	_	NOUN	_	Number=Plur	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	human	_	ADJ	_	Degree=Pos	_	_	_	_
43	NK	_	PROPN	_	Number=Sing	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	CD16	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	Fc	_	PROPN	_	Number=Sing	_	_	_	_
4	gamma	_	NOUN	_	Number=Sing	_	_	_	_
5	RIIIA	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
12	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	NK	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	via	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	CsA	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	Ca	_	PROPN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	+)-	_	SYM	_	_	_	_	_	_
27	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NK	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	CD16	_	PROPN	_	Number=Sing	_	_	_	_
7	ligands	_	NOUN	_	Number=Plur	_	_	_	_
8	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	like	_	ADJ	_	_	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	extracts	_	NOUN	_	Number=Plur	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	as	_	SCONJ	_	_	_	_	_	_
24	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
27	mobility	_	NOUN	_	Number=Sing	_	_	_	_
28	shift	_	NOUN	_	Number=Sing	_	_	_	_
29	assays	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	fast	_	ADJ	_	Degree=Pos	_	_	_	_
5	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
6	after	_	ADP	_	_	_	_	_	_
7	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	via	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	CsA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	Ca	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	+)-	_	SYM	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	require	_	VERB	_	VerbForm=Inf	_	_	_	_
25	de	_	PROPN	_	Number=Sing	_	_	_	_
26	novo	_	PROPN	_	Number=Sing	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	NK	_	PROPN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	present	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cytosol	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	nonstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	migrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
17	upon	_	ADP	_	_	_	_	_	_
18	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	can	_	AUX	_	VerbForm=Fin	_	_	_	_
22	associate	_	VERB	_	VerbForm=Inf	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	AP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
3	molecules	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	NFATp	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	NFATc	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	mediate	_	ADJ	_	VerbForm=Inf	_	_	_	_
14	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	supershift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	using	_	VERB	_	VerbForm=Ger	_	_	_	_
7	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	NFATc	_	ADJ	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
14	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	NK	_	PROPN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	early	_	ADV	_	Degree=Pos	_	_	_	_
20	after	_	ADP	_	_	_	_	_	_
21	CD16	_	PROPN	_	Number=Sing	_	_	_	_
22	ligand	_	NOUN	_	Number=Sing	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	primarily	_	ADV	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	if	_	SCONJ	_	_	_	_	_	_
28	not	_	ADV	_	_	_	_	_	_
29	exclusively	_	ADV	_	_	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	NFATp	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	Western	_	ADJ	_	Degree=Pos	_	_	_	_
35	blot	_	NOUN	_	Number=Sing	_	_	_	_
36	analysis	_	NOUN	_	Number=Sing	_	_	_	_
37	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	that	_	SCONJ	_	_	_	_	_	_
39	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
40	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	same	_	ADJ	_	Degree=Pos	_	_	_	_
43	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
44	mobility	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	approximately	_	ADV	_	_	_	_	_	_
47	120	_	NUM	_	NumType=Card	_	_	_	_
48	kD	_	NOUN	_	Number=Plur	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	as	_	ADP	_	_	_	_	_	_
51	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	T	_	PROPN	_	Number=Sing	_	_	_	_
54	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	NK	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	express	_	VERB	_	VerbForm=Inf	_	_	_	_
6	NFATc	_	PROPN	_	Number=Sing	_	_	_	_
7	constitutively	_	ADV	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	NFATc	_	PROPN	_	Degree=Pos	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	within	_	ADP	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	h	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	CD16	_	PROPN	_	Number=Sing	_	_	_	_
25	ligands	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	supershift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	using	_	VERB	_	VerbForm=Ger	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	available	_	ADJ	_	Degree=Pos	_	_	_	_
8	mAb	_	NOUN	_	Number=Sing	_	_	_	_
9	recognizing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	NFATc	_	PROPN	_	Number=Sing	_	_	_	_
14	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	no	_	DET	_	_	_	_	_	_
16	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
17	NFATc	_	PROPN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
23	extracts	_	NOUN	_	Number=Plur	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	CD16	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
29	ester	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	at	_	ADP	_	_	_	_	_	_
34	any	_	DET	_	_	_	_	_	_
35	time	_	NOUN	_	Number=Sing	_	_	_	_
36	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	up	_	ADP	_	_	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	4	_	NUM	_	NumType=Card	_	_	_	_
41	h	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	direct	_	ADJ	_	Degree=Pos	_	_	_	_
7	evidence	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	CsA	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	NFATc	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	NK	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	expression	_	NOUN	_	Number=Sing	_	_	_	_
35	can	_	AUX	_	VerbForm=Fin	_	_	_	_
36	be	_	AUX	_	VerbForm=Inf	_	_	_	_
37	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	primary	_	ADJ	_	Degree=Pos	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	single	_	ADJ	_	Degree=Pos	_	_	_	_
44	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	case	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	CD16	_	NOUN	_	Number=Sing	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	NK	_	PROPN	_	Number=Sing	_	_	_	_
55	cells	_	NOUN	_	Number=Plur	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	results	_	NOUN	_	Number=Plur	_	_	_	_
58	in	_	ADP	_	_	_	_	_	_
59	early	_	ADJ	_	Degree=Pos	_	_	_	_
60	activation	_	NOUN	_	Number=Sing	_	_	_	_
61	of	_	ADP	_	_	_	_	_	_
62	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
63	and	_	CCONJ	_	_	_	_	_	_
64	subsequently	_	ADV	_	_	_	_	_	_
65	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
66	expression	_	NOUN	_	Number=Sing	_	_	_	_
67	of	_	ADP	_	_	_	_	_	_
68	NFATc	_	ADJ	_	Number=Sing	_	_	_	_
69	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012565	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_
5	C	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	zeta	_	NOUN	_	Number=Sing	_	_	_	_
8	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	function	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	C	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	zeta	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	PKC	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	zeta	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	member	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
20	ester	_	NOUN	_	Number=Sing	_	_	_	_
21	nonresponsive	_	ADJ	_	Degree=Pos	_	_	_	_
22	atypical	_	ADJ	_	Degree=Pos	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	kinase	_	NOUN	_	Number=Sing	_	_	_	_
25	C	_	PROPN	_	Number=Sing	_	_	_	_
26	subfamily	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	modulating	_	VERB	_	Number=Sing	_	_	_	_
30	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
31	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
32	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
36	U937	_	NOUN	_	Number=Sing	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	U937	_	NUM	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	stably	_	ADV	_	_	_	_	_	_
5	overexpressing	_	VERB	_	VerbForm=Ger	_	_	_	_
6	PKC	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	zeta	_	NOUN	_	Number=Sing	_	_	_	_
9	displayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	longer	_	ADJ	_	Degree=Cmp	_	_	_	_
12	doubling	_	NOUN	_	Degree=Pos	_	_	_	_
13	time	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
16	saturation	_	NOUN	_	Number=Sing	_	_	_	_
17	density	_	NOUN	_	Number=Sing	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	confluency	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	increase	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	adherence	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	plastic	_	ADJ	_	Degree=Pos	_	_	_	_
28	as	_	SCONJ	_	_	_	_	_	_
29	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	control	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	PKC	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	zeta	_	NOUN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	more	_	ADV	_	_	_	_	_	_
8	differentiated	_	ADJ	_	Degree=Pos	_	_	_	_
9	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
10	as	_	SCONJ	_	_	_	_	_	_
11	assessed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	changes	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	morphology	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	surface	_	NOUN	_	Number=Sing	_	_	_	_
18	antigen	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	lysosomal	_	ADJ	_	Degree=Pos	_	_	_	_
23	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
24	activities	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	parental	_	ADJ	_	Degree=Pos	_	_	_	_
30	U937	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	exposure	_	NOUN	_	Number=Sing	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
39	esters	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	parental	_	ADJ	_	VerbForm=Inf	_	_	_	_
5	U937	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	PKC	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	zeta	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	constitutively	_	ADV	_	_	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	c	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	jun	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	low	_	ADJ	_	Degree=Pos	_	_	_	_
23	mobility	_	NOUN	_	Number=Sing	_	_	_	_
24	AP	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	binding	_	NOUN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	PKC	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	zeta	_	NOUN	_	Number=Sing	_	_	_	_
6	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
7	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	differs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	significantly	_	ADV	_	_	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	maturation	_	NOUN	_	Number=Sing	_	_	_	_
18	occurring	_	VERB	_	VerbForm=Ger	_	_	_	_
19	upon	_	ADP	_	_	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	other	_	ADJ	_	Degree=Pos	_	_	_	_
23	PKC	_	PROPN	_	Number=Sing	_	_	_	_
24	subfamilies	_	NOUN	_	Number=Plur	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
28	ester	_	NOUN	_	Number=Sing	_	_	_	_
29	treatment	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
6	protooncogene	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	increase	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	PKC	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	zeta	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	potential	_	ADJ	_	Degree=Pos	_	_	_	_
24	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
25	for	_	SCONJ	_	_	_	_	_	_
26	explaining	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
30	status	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012569	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	line	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
18	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Numerous	_	ADJ	_	Degree=Pos	_	_	_	_
2	genes	_	NOUN	_	Number=Plur	_	_	_	_
3	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	during	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	immune	_	NOUN	_	Number=Sing	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
9	response	_	NOUN	_	Number=Sing	_	_	_	_
10	as	_	ADV	_	_	_	_	_	_
11	well	_	ADV	_	Degree=Pos	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
15	process	_	NOUN	_	Number=Sing	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
4	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	kappaB	_	VERB	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	resides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
16	form	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	various	_	ADJ	_	Degree=Pos	_	_	_	_
5	agents	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	kappaB	_	VERB	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	proteolyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	ADJ	_	Number=Sing	_	_	_	_
15	translocates	_	VERB	_	Number=Plur	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	where	_	ADV	_	PronType=Rel	_	_	_	_
21	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
22	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	target	_	NOUN	_	Number=Sing	_	_	_	_
25	genes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transduction	_	NOUN	_	Number=Sing	_	_	_	_
3	pathways	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	kappaB	_	VERB	_	Degree=Pos	_	_	_	_
9	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
10	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	poorly	_	ADV	_	_	_	_	_	_
12	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	mutant	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	70	_	NUM	_	NumType=Card	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	Z3	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	1.3	_	NUM	_	NumType=Card	_	_	_	_
19	E2	_	NUM	_	Number=Sing	_	_	_	_
20	murine	_	NOUN	_	Number=Sing	_	_	_	_
21	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	response	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	several	_	ADJ	_	Degree=Pos	_	_	_	_
36	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	upon	_	ADP	_	_	_	_	_	_
5	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	Taxol	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
12	myristate	_	NOUN	_	Number=Sing	_	_	_	_
13	acetate	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	double	_	ADJ	_	Degree=Pos	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	RNA	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
26	kappaB	_	VERB	_	Number=Sing	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	not	_	PART	_	_	_	_	_	_
30	degraded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	result	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	absence	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
41	on	_	ADP	_	_	_	_	_	_
42	serines	_	NOUN	_	Number=Sing	_	_	_	_
43	32	_	NUM	_	NumType=Card	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	36	_	NUM	_	NumType=Card	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Neither	_	CCONJ	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	mutation	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	kappaB	_	VERB	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	nor	_	CCONJ	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	mutation	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	p50	_	NUM	_	Number=Sing	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	relA	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	major	_	ADJ	_	Degree=Pos	_	_	_	_
19	subunits	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	line	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	accounts	_	NOUN	_	Number=Plur	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
32	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
33	defect	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADV	_	_	_	_	_	_
2	well	_	ADV	_	Degree=Pos	_	_	_	_
3	as	_	ADP	_	_	_	_	_	_
4	culminating	_	VERB	_	VerbForm=Ger	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
8	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	kappaB	_	VERB	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	serines	_	NOUN	_	Number=Plur	_	_	_	_
15	32	_	NUM	_	NumType=Card	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	36	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	all	_	DET	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	1.3	_	NUM	_	NumType=Card	_	_	_	_
27	E2	_	NUM	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	exhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	antioxidant	_	NOUN	_	Number=Sing	_	_	_	_
35	pyrrolidine	_	NOUN	_	Number=Sing	_	_	_	_
36	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	PDTC	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	stimuli	_	NOUN	_	_	_	_	_	_
5	such	_	ADJ	_	Degree=Pos	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	hyperosmotic	_	ADJ	_	Degree=Pos	_	_	_	_
8	shock	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
11	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	use	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	PDTC	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	insensitive	_	ADJ	_	Degree=Pos	_	_	_	_
18	pathways	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	induce	_	VERB	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	kappaB	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	degradation	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	1.3E2	_	NUM	_	NumType=Card	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	redox	_	NOUN	_	Number=Sing	_	_	_	_
5	status	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	1.3	_	NUM	_	NumType=Card	_	_	_	_
8	E2	_	NUM	_	Number=Sing	_	_	_	_
9	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	reveal	_	VERB	_	VerbForm=Inf	_	_	_	_
12	any	_	DET	_	_	_	_	_	_
13	difference	_	NOUN	_	Number=Sing	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	wild	_	ADJ	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	70Z	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	3	_	NUM	_	NumType=Card	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
8	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
9	virus	_	NOUN	_	Number=Sing	_	_	_	_
10	type	_	NOUN	_	Number=Sing	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	Tax	_	NOUN	_	Number=Sing	_	_	_	_
20	trans	_	NOUN	_	Number=Plur	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	activator	_	NOUN	_	Number=Sing	_	_	_	_
23	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	1.3E2	_	NUM	_	NumType=Card	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	that	_	SCONJ	_	_	_	_	_	_
33	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
34	viral	_	ADJ	_	Degree=Pos	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	not	_	PART	_	_	_	_	_	_
38	operate	_	VERB	_	VerbForm=Inf	_	_	_	_
39	via	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	defective	_	ADJ	_	Degree=Pos	_	_	_	_
42	pathway	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	other	_	ADJ	_	Degree=Pos	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	kappaB	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	molecules	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	kappaB	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	recently	_	ADV	_	_	_	_	_	_
18	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
20	kappaB	_	VERB	_	Number=Sing	_	_	_	_
21	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	degraded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	1.3	_	NUM	_	NumType=Card	_	_	_	_
29	E2	_	NUM	_	NumType=Card	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	line	_	NOUN	_	Number=Sing	_	_	_	_
32	following	_	VERB	_	VerbForm=Ger	_	_	_	_
33	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	1.3	_	NUM	_	NumType=Card	_	_	_	_
6	E2	_	NUM	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	transduction	_	NOUN	_	Number=Sing	_	_	_	_
11	mutant	_	NOUN	_	Number=Sing	_	_	_	_
12	exhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	defect	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	step	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	several	_	ADJ	_	Degree=Pos	_	_	_	_
23	different	_	ADJ	_	Degree=Pos	_	_	_	_
24	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	common	_	ADJ	_	Degree=Pos	_	_	_	_
9	step	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	signaling	_	NOUN	_	Number=Sing	_	_	_	_
13	pathways	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	trigger	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	kappaB	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	kappaB	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	beta	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
26	kappaB	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
28	degradation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012570	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	RP1	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	new	_	ADJ	_	Degree=Pos	_	_	_	_
5	member	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	adenomatous	_	ADJ	_	Degree=Pos	_	_	_	_
9	polyposis	_	ADJ	_	Number=Sing	_	_	_	_
10	coli	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
13	EB1	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	like	_	ADJ	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	family	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	differentially	_	ADV	_	_	_	_	_	_
21	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Cross	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	linking	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	CD3	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	CD28	_	PROPN	_	Number=Sing	_	_	_	_
9	molecules	_	NOUN	_	Number=Plur	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	one	_	NUM	_	NumType=Card	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	most	_	ADV	_	_	_	_	_	_
18	effective	_	ADJ	_	Degree=Pos	_	_	_	_
19	signals	_	NOUN	_	Number=Plur	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	T	_	ADJ	_	Number=Sing	_	_	_	_
22	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	triggering	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
29	effector	_	NOUN	_	Number=Sing	_	_	_	_
30	function	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
3	genes	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	after	_	ADP	_	_	_	_	_	_
11	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	simultaneous	_	ADJ	_	Degree=Pos	_	_	_	_
24	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	CD3	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	CD28	_	PROPN	_	Number=Sing	_	_	_	_
30	trigger	_	NOUN	_	Number=Sing	_	_	_	_
31	molecules	_	NOUN	_	Number=Plur	_	_	_	_
32	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
33	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	differential	_	ADJ	_	Degree=Pos	_	_	_	_
37	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
38	display	_	NOUN	_	Number=Sing	_	_	_	_
39	analysis	_	NOUN	_	Number=Sing	_	_	_	_
40	into	_	ADP	_	_	_	_	_	_
41	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
44	compared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	with	_	ADP	_	_	_	_	_	_
46	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
47	from	_	ADP	_	_	_	_	_	_
48	CD28	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	or	_	CCONJ	_	_	_	_	_	_
51	CD3	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
54	or	_	CCONJ	_	_	_	_	_	_
55	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
56	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	subsequently	_	ADV	_	_	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
8	blot	_	PROPN	_	Number=Sing	_	_	_	_
9	analysis	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
5	fragments	_	NOUN	_	Number=Plur	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	specifically	_	ADV	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	CD3	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	CD28	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	designated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	RP1	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	predictive	_	ADJ	_	Degree=Pos	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	coding	_	NOUN	_	Number=Sing	_	_	_	_
6	region	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	RP1	_	NOUN	_	Number=Sing	_	_	_	_
9	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	significant	_	ADJ	_	Degree=Pos	_	_	_	_
12	homology	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	members	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	recently	_	ADV	_	_	_	_	_	_
18	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	adenomatous	_	ADJ	_	Degree=Pos	_	_	_	_
20	polyposis	_	PROPN	_	Number=Sing	_	_	_	_
21	coli	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	APC	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
28	EB1	_	PROPN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	family	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	which	_	PRON	_	PronType=Rel	_	_	_	_
33	codes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	yet	_	ADV	_	_	_	_	_	_
36	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
37	protein	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	s	_	X	_	_	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Bacterially	_	ADV	_	_	_	_	_	_
2	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	RP1	_	NOUN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	wild	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	type	_	NOUN	_	Number=Sing	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	mutated	_	VERB	_	VerbForm=Inf	_	_	_	_
16	APC	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
3	up	_	ADP	_	_	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	RP1	_	NOUN	_	Number=Sing	_	_	_	_
8	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	properly	_	ADV	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	might	_	AUX	_	VerbForm=Fin	_	_	_	_
19	belong	_	VERB	_	VerbForm=Inf	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	early	_	ADJ	_	Degree=Pos	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	family	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	controls	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	signal	_	NOUN	_	Number=Sing	_	_	_	_
32	transduction	_	NOUN	_	Number=Sing	_	_	_	_
33	cascade	_	NOUN	_	Number=Sing	_	_	_	_
34	downstream	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	TCR	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	level	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	RP1	_	PROPN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	spectrum	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	tumor	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	lines	_	NOUN	_	Number=Plur	_	_	_	_
22	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
26	status	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	members	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	EB1	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	like	_	ADJ	_	Degree=Pos	_	_	_	_
37	gene	_	NOUN	_	Number=Sing	_	_	_	_
38	family	_	NOUN	_	Number=Sing	_	_	_	_
39	may	_	AUX	_	VerbForm=Fin	_	_	_	_
40	not	_	PART	_	_	_	_	_	_
41	only	_	ADV	_	_	_	_	_	_
42	be	_	AUX	_	VerbForm=Inf	_	_	_	_
43	involved	_	ADJ	_	Degree=Pos	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	tumorigenesis	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	colorectal	_	ADJ	_	Degree=Pos	_	_	_	_
49	cancers	_	NOUN	_	Number=Plur	_	_	_	_
50	but	_	CCONJ	_	_	_	_	_	_
51	may	_	AUX	_	VerbForm=Fin	_	_	_	_
52	also	_	ADV	_	_	_	_	_	_
53	play	_	VERB	_	VerbForm=Inf	_	_	_	_
54	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
55	role	_	NOUN	_	Number=Sing	_	_	_	_
56	in	_	ADP	_	_	_	_	_	_
57	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
58	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
59	control	_	NOUN	_	Number=Sing	_	_	_	_
60	of	_	ADP	_	_	_	_	_	_
61	normal	_	ADJ	_	Degree=Pos	_	_	_	_
62	cells	_	NOUN	_	Number=Plur	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012571	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Non	_	X	_	_	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	steroidal	_	ADJ	_	Degree=Pos	_	_	_	_
4	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	drugs	_	NOUN	_	Number=Plur	_	_	_	_
6	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	induce	_	VERB	_	Degree=Pos	_	_	_	_
13	HSP70	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	non-steroidal	_	ADJ	_	Degree=Pos	_	_	_	_
8	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	drugs	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	NSAIDs	_	NOUN	_	Number=Plur	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	activate	_	VERB	_	Degree=Pos	_	_	_	_
14	heat	_	NOUN	_	Number=Sing	_	_	_	_
15	shock	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	HSF1	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	latent	_	ADJ	_	Degree=Pos	_	_	_	_
24	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
25	form	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	DNA	_	PROPN	_	Number=Sing	_	_	_	_
31	binding	_	NOUN	_	Number=Sing	_	_	_	_
32	state	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	HSF1	_	PROPN	_	Number=Sing	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	function	_	VERB	_	VerbForm=Inf	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	activator	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	heat	_	NOUN	_	Number=Sing	_	_	_	_
11	shock	_	NOUN	_	Number=Sing	_	_	_	_
12	genes	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	repressor	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	non	_	ADJ	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	heat	_	NOUN	_	Number=Sing	_	_	_	_
20	shock	_	NOUN	_	Number=Sing	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	such	_	ADJ	_	Degree=Pos	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	IL1B	_	PROPN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	c-	_	NOUN	_	Number=Sing	_	_	_	_
27	fos	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
30	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	potential	_	ADJ	_	Degree=Pos	_	_	_	_
34	role	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	HSF1	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	effects	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	NSAIDs	_	NOUN	_	Number=Sing	_	_	_	_
42	on	_	ADP	_	_	_	_	_	_
43	gene	_	NOUN	_	Number=Sing	_	_	_	_
44	expression	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
47	human	_	ADJ	_	Degree=Pos	_	_	_	_
48	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
49	cell	_	NOUN	_	Number=Sing	_	_	_	_
50	line	_	NOUN	_	Number=Sing	_	_	_	_
51	THP	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	1	_	NUM	_	NumType=Card	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	members	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	NSAIDs	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	sodium	_	NOUN	_	Number=Sing	_	_	_	_
11	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	sulindac	_	NOUN	_	Number=Sing	_	_	_	_
14	repress	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	IL1B	_	PROPN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	similar	_	ADJ	_	Degree=Pos	_	_	_	_
20	degree	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	heat	_	NOUN	_	Number=Sing	_	_	_	_
23	shock	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	HSF1	_	NOUN	_	Number=Sing	_	_	_	_
26	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	sodium	_	NOUN	_	Number=Sing	_	_	_	_
5	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	additional	_	ADJ	_	Degree=Pos	_	_	_	_
8	NSAIDs	_	NOUN	_	Number=Plur	_	_	_	_
9	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	HSF1	_	PROPN	_	Number=Sing	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	other	_	ADJ	_	Degree=Pos	_	_	_	_
21	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	TNF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	alpha	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1beta	_	PROPN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	6	_	NUM	_	NumType=Card	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	8	_	NUM	_	NumType=Card	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	10	_	NUM	_	NumType=Card	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	by	_	ADP	_	_	_	_	_	_
50	exposure	_	NOUN	_	Number=Sing	_	_	_	_
51	to	_	ADP	_	_	_	_	_	_
52	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
53	pro-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
54	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
55	(	_	PUNCT	_	_	_	_	_	_
56	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	LPS	_	PROPN	_	Number=Sing	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	At	_	ADV	_	_	_	_	_	_
2	least	_	ADV	_	Degree=Sup	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	case	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IL1B	_	PROPN	_	Number=Sing	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	repression	_	NOUN	_	Number=Sing	_	_	_	_
12	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	seem	_	VERB	_	VerbForm=Inf	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
17	another	_	DET	_	_	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	NSAIDs	_	PROPN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
28	as	_	SCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	IL1B	_	PROPN	_	Number=Sing	_	_	_	_
31	promoter	_	NOUN	_	Number=Sing	_	_	_	_
32	fragment	_	NOUN	_	Number=Sing	_	_	_	_
33	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
36	studies	_	NOUN	_	Number=Plur	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	not	_	PART	_	_	_	_	_	_
39	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
40	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
43	specifically	_	ADV	_	_	_	_	_	_
44	to	_	ADP	_	_	_	_	_	_
45	HSF1	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Exposure	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	NSAIDs	_	PROPN	_	Number=Sing	_	_	_	_
4	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	complex	_	ADJ	_	Degree=Pos	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	HSP	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	while	_	SCONJ	_	_	_	_	_	_
14	sulindac	_	NOUN	_	Number=Sing	_	_	_	_
15	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	stress	_	NOUN	_	Number=Sing	_	_	_	_
18	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
19	HSP70B	_	NOUN	_	Number=Sing	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	sodium	_	NOUN	_	Number=Sing	_	_	_	_
23	salicylate	_	NOUN	_	Number=Sing	_	_	_	_
24	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	only	_	ADV	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	subset	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	NSAIDs	_	PROPN	_	Number=Plur	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	HSP70	_	ADJ	_	Number=Sing	_	_	_	_
12	mRNA	_	ADJ	_	Number=Sing	_	_	_	_
13	species	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	reflect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	properties	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	HSF1	_	NOUN	_	Number=Sing	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	at	_	ADV	_	_	_	_	_	_
14	least	_	ADV	_	Degree=Sup	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	DNA	_	PROPN	_	Number=Sing	_	_	_	_
17	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
18	forms	_	NOUN	_	Number=Plur	_	_	_	_
19	only	_	ADV	_	_	_	_	_	_
20	one	_	NUM	_	NumType=Card	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Int	_	_	_	_
23	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	heat	_	NOUN	_	Number=Sing	_	_	_	_
25	shock	_	NOUN	_	Number=Sing	_	_	_	_
26	promoters	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	individual	_	ADJ	_	Degree=Pos	_	_	_	_
31	NSAID	_	ADJ	_	Number=Sing	_	_	_	_
32	family	_	NOUN	_	Number=Sing	_	_	_	_
33	members	_	NOUN	_	Number=Plur	_	_	_	_
34	may	_	AUX	_	VerbForm=Fin	_	_	_	_
35	differentially	_	ADV	_	_	_	_	_	_
36	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
37	one	_	NUM	_	NumType=Card	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	other	_	ADJ	_	Degree=Pos	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
42	forms	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Overall	_	ADV	_	_	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	exposure	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	NSAIDs	_	PROPN	_	Number=Sing	_	_	_	_
7	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	profound	_	ADJ	_	Degree=Pos	_	_	_	_
11	switch	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	suppression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	involved	_	ADJ	_	Degree=Pos	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	induction	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	stress	_	NOUN	_	Number=Sing	_	_	_	_
31	genes	_	NOUN	_	Number=Plur	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	HSF1	_	NOUN	_	Number=Sing	_	_	_	_
34	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	play	_	VERB	_	VerbForm=Inf	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
39	role	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
42	effects	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1999	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012572	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Modulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	novel	_	NOUN	_	Number=Sing	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	selective	_	ADJ	_	Degree=Pos	_	_	_	_
12	CCAAT	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	VERB	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
20	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
3	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	newly	_	ADV	_	_	_	_	_	_
7	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	coding	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	CCAAT	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	may	_	AUX	_	VerbForm=Fin	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	involved	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	regulation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
26	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
8	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	markedly	_	ADV	_	_	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	NB4	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	promyelocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
19	line	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	because	_	SCONJ	_	_	_	_	_	_
23	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	9	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	cis	_	NOUN	_	Number=Sing	_	_	_	_
30	retinoic	_	ADJ	_	Number=Sing	_	_	_	_
31	acid	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	9	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	cis	_	NOUN	_	Number=Sing	_	_	_	_
36	RA	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
40	towards	_	ADP	_	_	_	_	_	_
41	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Accumulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
4	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
5	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
6	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	as	_	ADV	_	_	_	_	_	_
8	early	_	ADV	_	Degree=Pos	_	_	_	_
9	as	_	ADP	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	hour	_	NOUN	_	Number=Sing	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	exposure	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NB4	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	9-cis	_	PROPN	_	Number=Sing	_	_	_	_
19	RA	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	5	_	NUM	_	NumType=Card	_	_	_	_
22	x	_	SYM	_	_	_	_	_	_
23	10	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	7	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	mol	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	L	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	;	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	at	_	ADP	_	_	_	_	_	_
35	48	_	NUM	_	NumType=Card	_	_	_	_
36	hours	_	NOUN	_	Number=Plur	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	levels	_	NOUN	_	Number=Plur	_	_	_	_
39	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	5.1-	_	NUM	_	NumType=Card	_	_	_	_
43	fold	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Dose	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	response	_	NOUN	_	Number=Sing	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	10	_	NUM	_	NumType=Card	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	-	_	SYM	_	_	_	_	_	_
10	7	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	10	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	-	_	SYM	_	_	_	_	_	_
16	6	_	NUM	_	NumType=Card	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	mol	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	L	_	PROPN	_	Number=Sing	_	_	_	_
21	9-cis	_	PROPN	_	Number=Sing	_	_	_	_
22	RA	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	12	_	NUM	_	NumType=Card	_	_	_	_
25	hours	_	NOUN	_	Number=Plur	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	peak	_	NOUN	_	Number=Sing	_	_	_	_
30	levels	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
33	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
34	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
35	;	_	PUNCT	_	_	_	_	_	_
36	but	_	CCONJ	_	_	_	_	_	_
37	even	_	ADV	_	_	_	_	_	_
38	10	_	NUM	_	NumType=Card	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	-	_	SYM	_	_	_	_	_	_
41	10	_	NUM	_	NumType=Card	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	mol	_	NOUN	_	Number=Sing	_	_	_	_
44	/	_	PUNCT	_	_	_	_	_	_
45	L	_	SYM	_	Number=Sing	_	_	_	_
46	9-cis	_	PROPN	_	Number=Sing	_	_	_	_
47	RA	_	PROPN	_	Number=Sing	_	_	_	_
48	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	levels	_	NOUN	_	Number=Plur	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
52	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	NB4	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	pulse	_	VERB	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	30	_	NUM	_	NumType=Card	_	_	_	_
8	minutes	_	NOUN	_	Number=Plur	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	all	_	DET	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	trans	_	NOUN	_	Number=Sing	_	_	_	_
14	retinoic	_	PROPN	_	Degree=Pos	_	_	_	_
15	acid	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	washed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	3	_	NUM	_	NumType=Card	_	_	_	_
26	days	_	NOUN	_	Number=Plur	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	either	_	CCONJ	_	_	_	_	_	_
30	dimethylsulfoxide	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	DMSO	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	hexamethylene	_	ADJ	_	Number=Sing	_	_	_	_
36	bisacetamide	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	HMBA	_	PROPN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	prominent	_	ADJ	_	Degree=Pos	_	_	_	_
43	increase	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	levels	_	NOUN	_	Number=Plur	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
48	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
49	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
52	increase	_	NOUN	_	Number=Sing	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
55	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	but	_	CCONJ	_	_	_	_	_	_
58	exposure	_	NOUN	_	Number=Sing	_	_	_	_
59	to	_	ADP	_	_	_	_	_	_
60	either	_	CCONJ	_	_	_	_	_	_
61	DMSO	_	PROPN	_	Number=Sing	_	_	_	_
62	or	_	CCONJ	_	_	_	_	_	_
63	HMBA	_	PROPN	_	Number=Sing	_	_	_	_
64	alone	_	ADV	_	_	_	_	_	_
65	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
66	no	_	DET	_	_	_	_	_	_
67	effect	_	NOUN	_	Number=Sing	_	_	_	_
68	on	_	ADP	_	_	_	_	_	_
69	base	_	NOUN	_	Number=Sing	_	_	_	_
70	levels	_	NOUN	_	Number=Plur	_	_	_	_
71	of	_	ADP	_	_	_	_	_	_
72	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
73	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
74	and	_	CCONJ	_	_	_	_	_	_
75	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
76	not	_	PART	_	_	_	_	_	_
77	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
78	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
79	.	_	PUNCT	_	_	_	_	_	_

1	Macrophage	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NB4	_	PROPN	_	Number=Sing	_	_	_	_
6	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	C	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	EBP	_	PROPN	_	Number=Sing	_	_	_	_
12	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	run	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	off	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	half	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	life	_	NOUN	_	Number=Sing	_	_	_	_
10	studies	_	NOUN	_	Number=Plur	_	_	_	_
11	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
16	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
17	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	9-cis	_	PROPN	_	Number=Sing	_	_	_	_
20	RA	_	PROPN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	due	_	ADP	_	_	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
5	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
6	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
7	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
8	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	require	_	VERB	_	VerbForm=Inf	_	_	_	_
11	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	new	_	ADJ	_	Degree=Pos	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	because	_	SCONJ	_	_	_	_	_	_
17	9	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	cis	_	NOUN	_	Number=Sing	_	_	_	_
20	RA	_	PROPN	_	Number=Sing	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
23	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
24	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
25	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	absence	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	new	_	ADJ	_	Degree=Pos	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	ATRA	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
7	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	NB4	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	as	_	SCONJ	_	_	_	_	_	_
14	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	Western	_	ADJ	_	Degree=Pos	_	_	_	_
17	blotting	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	increase	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
8	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	9-cis	_	PROPN	_	NumType=Card	_	_	_	_
11	RA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	mediated	_	VERB	_	Degree=Pos	_	_	_	_
14	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	DMSO	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	HL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	60	_	NUM	_	NumType=Card	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	down	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
30	pathway	_	NOUN	_	Number=Sing	_	_	_	_
31	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
32	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	initial	_	ADJ	_	Degree=Pos	_	_	_	_
36	reduction	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
39	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
40	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
41	levels	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	summary	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	discovered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
11	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
12	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	markedly	_	ADV	_	_	_	_	_	_
15	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	as	_	SCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	NB4	_	NOUN	_	Number=Sing	_	_	_	_
19	promyelocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	retinoids	_	NOUN	_	Number=Plur	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	towards	_	ADP	_	_	_	_	_	_
27	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
5	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
6	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	transcriptionally	_	ADV	_	_	_	_	_	_
10	mediated	_	VERB	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	absence	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	additional	_	ADJ	_	Degree=Pos	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	suspect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
6	epsilon	_	NOUN	_	Number=Sing	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
10	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
13	acid	_	ADJ	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	directly	_	ADV	_	_	_	_	_	_
20	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	retinoids	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012573	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Signalling	_	VERB	_	VerbForm=Ger	_	_	_	_
2	via	_	ADP	_	_	_	_	_	_
3	CD28	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	naive	_	ADJ	_	Degree=Pos	_	_	_	_
7	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Accessory	_	ADJ	_	Degree=Pos	_	_	_	_
2	molecules	_	NOUN	_	Number=Plur	_	_	_	_
3	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	development	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	antigenic	_	ADJ	_	Degree=Pos	_	_	_	_
17	challenge	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CD28	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	SCONJ	_	_	_	_	_	_
9	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	'	_	PUNCT	_	_	_	_	_	_
12	naive	_	ADJ	_	Degree=Pos	_	_	_	_
13	'	_	PUNCT	_	_	_	_	_	_
14	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	response	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	anti-CD2	_	ADJ	_	Degree=Pos	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	compare	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CD28	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	adult	_	NOUN	_	Number=Sing	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	pair	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
20	anti-CD2	_	ADJ	_	Degree=Pos	_	_	_	_
21	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	presence	_	NOUN	_	Number=Sing	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	absence	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	anti-CD28	_	ADJ	_	Number=Sing	_	_	_	_
29	MoAb	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	With	_	ADP	_	_	_	_	_	_
2	anti-CD2	_	PROPN	_	Number=Sing	_	_	_	_
3	alone	_	ADV	_	_	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	proliferated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	slightly	_	ADV	_	_	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	no	_	DET	_	_	_	_	_	_
13	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	whereas	_	SCONJ	_	_	_	_	_	_
19	adult	_	NOUN	_	Number=Sing	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	proliferated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	vigorously	_	ADV	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	significant	_	ADJ	_	Degree=Pos	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	production	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Costimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	anti-CD28	_	PROPN	_	Number=Sing	_	_	_	_

1	MoAb	_	PROPN	_	Number=Sing	_	_	_	_
2	greatly	_	ADV	_	_	_	_	_	_
3	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	levels	_	NOUN	_	Number=Plur	_	_	_	_
13	equivalent	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	adult	_	NOUN	_	Degree=Pos	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whereas	_	SCONJ	_	_	_	_	_	_
22	adult	_	NOUN	_	Degree=Pos	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	only	_	ADV	_	_	_	_	_	_
27	slight	_	ADJ	_	Degree=Pos	_	_	_	_
28	increases	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	secretion	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	presence	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	anti-CD28	_	PROPN	_	Number=Sing	_	_	_	_
13	MoAb	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	neonatal	_	ADJ	_	Number=Sing	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	production	_	NOUN	_	Number=Sing	_	_	_	_
22	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
24	than	_	ADP	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	adults	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	enhancement	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	neonates	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	similar	_	ADJ	_	Degree=Pos	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	adult	_	NOUN	_	VerbForm=Inf	_	_	_	_
17	levels	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Anti-CD28	_	PROPN	_	Number=Sing	_	_	_	_

1	MoAb	_	PROPN	_	Number=Sing	_	_	_	_
2	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	neonates	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	albeit	_	SCONJ	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	levels	_	VERB	_	Number=Plur	_	_	_	_
14	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
15	than	_	ADP	_	_	_	_	_	_
16	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	adults	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
4	governing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	diminished	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
7	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
8	response	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	neonatal	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	anti-CD2	_	PROPN	_	VerbForm=Inf	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	therefore	_	ADV	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	due	_	ADP	_	_	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	kappa	_	NOUN	_	Number=Sing	_	_	_	_
23	B	_	NOUN	_	Number=Sing	_	_	_	_
24	induction	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	production	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	anti-CD28	_	PROPN	_	Number=Sing	_	_	_	_

1	MoAb	_	PROPN	_	Number=Sing	_	_	_	_
2	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
3	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	all	_	DET	_	_	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	above	_	ADJ	_	Degree=Pos	_	_	_	_
8	signals	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	kappa	_	PROPN	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	levels	_	NOUN	_	Number=Plur	_	_	_	_
18	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
20	than	_	ADP	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	adults	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	need	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	further	_	ADJ	_	Degree=Pos	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	requirements	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	neonate	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012579	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	c	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	Rel	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	p65	_	NUM	_	Number=Sing	_	_	_	_
6	subunits	_	NOUN	_	Number=Plur	_	_	_	_
7	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
18	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	colony	_	NOUN	_	Number=Sing	_	_	_	_
21	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	involved	_	ADJ	_	Degree=Pos	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
27	ester	_	NOUN	_	Number=Sing	_	_	_	_
28	response	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	5637	_	NUM	_	NumType=Card	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	clarify	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	complex	_	ADJ	_	Number=Sing	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	GM	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	CSF	_	PROPN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	extensively	_	ADV	_	_	_	_	_	_
19	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
26	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	role	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
36	like	_	ADP	_	_	_	_	_	_
37	site	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	5637	_	NUM	_	NumType=Card	_	_	_	_
41	non-lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	line	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	which	_	PRON	_	PronType=Rel	_	_	_	_
46	derives	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
47	from	_	ADP	_	_	_	_	_	_
48	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
49	bladder	_	NOUN	_	Number=Sing	_	_	_	_
50	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	constitutively	_	ADV	_	Number=Sing	_	_	_	_
53	produces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
54	GM	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	CSF	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	named	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	active	_	ADJ	_	Degree=Pos	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	GM	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	CSF	_	PROPN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	tumor	_	NOUN	_	Number=Sing	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	PMA	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	transient	_	ADJ	_	Degree=Pos	_	_	_	_
28	transfection	_	NOUN	_	Number=Sing	_	_	_	_
29	experiments	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	heterodimeric	_	ADJ	_	Degree=Pos	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	complex	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	subunits	_	NOUN	_	Number=Plur	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	c	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	Rel	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	p65	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	identical	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	one	_	NOUN	_	Number=Sing	_	_	_	_
26	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	using	_	VERB	_	VerbForm=Ger	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	HIV	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	LTR	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	site	_	NOUN	_	Number=Sing	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	recognition	_	NOUN	_	Number=Sing	_	_	_	_
37	sequence	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	different	_	ADJ	_	Degree=Pos	_	_	_	_
40	from	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	one	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	c	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	Rel	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	p50	_	NOUN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	with	_	ADP	_	_	_	_	_	_
52	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
53	extracts	_	NOUN	_	Number=Plur	_	_	_	_
54	from	_	ADP	_	_	_	_	_	_
55	Mo	_	PROPN	_	Number=Sing	_	_	_	_
56	T-lymphoid	_	PROPN	_	Number=Sing	_	_	_	_
57	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	II	_	NUM	_	NumType=Card	_	_	_	_
60	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
61	cells	_	NOUN	_	Number=Plur	_	_	_	_
62	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012580	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Ubiquitin	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	processing	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	activator	_	NOUN	_	Number=Sing	_	_	_	_
12	precursor	_	NOUN	_	Number=Sing	_	_	_	_
13	p105	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Reconstitution	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	free	_	ADJ	_	Degree=Pos	_	_	_	_
7	system	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	identification	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	ubiquitin	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	carrier	_	NOUN	_	Number=Sing	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	E2	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	novel	_	NOUN	_	Number=Sing	_	_	_	_
22	ubiquitin	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	ligase	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	E3	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	involved	_	ADJ	_	Degree=Pos	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	conjugation	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	most	_	ADJ	_	Degree=Sup	_	_	_	_
3	cases	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	PROPN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
15	consisting	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	subunits	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	p50	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	p65	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	encoded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	two	_	NUM	_	NumType=Card	_	_	_	_
29	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	Rel	_	PROPN	_	Number=Sing	_	_	_	_
34	family	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	p50	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	translated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	precursor	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	105	_	NUM	_	NumType=Card	_	_	_	_
9	kDa	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	C-	_	NOUN	_	Number=Sing	_	_	_	_
3	terminal	_	ADJ	_	Number=Sing	_	_	_	_
4	domain	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	precursor	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	rapidly	_	ADV	_	_	_	_	_	_
10	degraded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	mature	_	ADJ	_	Degree=Pos	_	_	_	_
15	p50	_	NUM	_	Number=Sing	_	_	_	_
16	subunit	_	NOUN	_	Number=Sing	_	_	_	_
17	consisted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	N	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	terminal	_	ADJ	_	Number=Sing	_	_	_	_
23	region	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	molecule	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	generation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	p50	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	ubiquitin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	proteasome	_	NOUN	_	Degree=Pos	_	_	_	_
10	system	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	involved	_	ADJ	_	Degree=Pos	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	process	_	NOUN	_	Number=Sing	_	_	_	_
16	;	_	PUNCT	_	_	_	_	_	_
17	however	_	ADV	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	enzymes	_	NOUN	_	Number=Plur	_	_	_	_
22	involved	_	ADJ	_	Degree=Pos	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	limited	_	ADJ	_	Degree=Pos	_	_	_	_
28	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	which	_	DET	_	PronType=Rel	_	_	_	_
32	half	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	molecule	_	NOUN	_	Number=Sing	_	_	_	_
36	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	spared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
41	obscure	_	ADJ	_	Degree=Pos	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Palombella	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	colleagues	_	NOUN	_	Number=Plur	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	Palombella	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	V.J.	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	Rando	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	O.J.	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	Goldberg	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	A.L.	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	Maniatis	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	T.	_	PROPN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	1994	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	Cell	_	NOUN	_	Number=Sing	_	_	_	_
25	78	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	773-785	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	ubiquitin	_	NOUN	_	Number=Sing	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	processing	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	cell	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	free	_	ADJ	_	Degree=Pos	_	_	_	_
43	system	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
46	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	artificially	_	ADV	_	_	_	_	_	_
49	constructed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	60	_	NUM	_	NumType=Card	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	kDa	_	NOUN	_	Number=Sing	_	_	_	_
54	precursor	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	They	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	proteasome	_	NOUN	_	Degree=Pos	_	_	_	_
7	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
8	block	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	processing	_	NOUN	_	Number=Sing	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vitro	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	vivo	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	reconstitution	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	free	_	ADJ	_	Degree=Pos	_	_	_	_
13	processing	_	NOUN	_	Number=Sing	_	_	_	_
14	system	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	directly	_	ADV	_	_	_	_	_	_
18	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	a	_	X	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	ubiquitin	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	proteasome	_	NOUN	_	Degree=Pos	_	_	_	_
27	system	_	NOUN	_	Number=Sing	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	involved	_	ADJ	_	Degree=Pos	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	processing	_	VERB	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	intact	_	NOUN	_	Number=Sing	_	_	_	_
35	p105	_	NOUN	_	Number=Sing	_	_	_	_
36	precursor	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	b	_	X	_	_	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	conjugation	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	ubiquitin	_	NOUN	_	Number=Sing	_	_	_	_
44	to	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	precursor	_	NOUN	_	Number=Sing	_	_	_	_
47	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
48	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
49	essential	_	ADJ	_	Degree=Pos	_	_	_	_
50	intermediate	_	ADJ	_	Degree=Pos	_	_	_	_
51	step	_	NOUN	_	Number=Sing	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	processing	_	NOUN	_	Number=Sing	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	(	_	PUNCT	_	_	_	_	_	_
57	c	_	X	_	_	_	_	_	_
58	)	_	PUNCT	_	_	_	_	_	_
59	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
60	recently	_	ADV	_	_	_	_	_	_
61	discovered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
62	novel	_	NOUN	_	Number=Sing	_	_	_	_
63	species	_	NOUN	_	Number=Plur	_	_	_	_
64	of	_	ADP	_	_	_	_	_	_
65	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
66	ubiquitin	_	NOUN	_	Number=Sing	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	carrier	_	NOUN	_	Number=Sing	_	_	_	_
69	protein	_	NOUN	_	Number=Sing	_	_	_	_
70	,	_	PUNCT	_	_	_	_	_	_
71	E2	_	PROPN	_	Number=Sing	_	_	_	_
72	-	_	PUNCT	_	_	_	_	_	_
73	F1	_	NOUN	_	Number=Sing	_	_	_	_
74	,	_	PUNCT	_	_	_	_	_	_
75	that	_	PRON	_	PronType=Rel	_	_	_	_
76	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
77	involved	_	ADJ	_	Degree=Pos	_	_	_	_
78	in	_	ADP	_	_	_	_	_	_
79	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
80	conjugation	_	NOUN	_	Number=Sing	_	_	_	_
81	and	_	CCONJ	_	_	_	_	_	_
82	degradation	_	NOUN	_	Number=Sing	_	_	_	_
83	of	_	ADP	_	_	_	_	_	_
84	p53	_	NOUN	_	Number=Sing	_	_	_	_
85	,	_	PUNCT	_	_	_	_	_	_
86	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
87	also	_	ADV	_	_	_	_	_	_
88	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
89	for	_	ADP	_	_	_	_	_	_
90	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
91	limited	_	ADJ	_	Degree=Pos	_	_	_	_
92	processing	_	NOUN	_	Number=Sing	_	_	_	_
93	of	_	ADP	_	_	_	_	_	_
94	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
95	p105	_	NOUN	_	Number=Sing	_	_	_	_
96	precursor	_	NOUN	_	Number=Sing	_	_	_	_
97	,	_	PUNCT	_	_	_	_	_	_
98	and	_	CCONJ	_	_	_	_	_	_
99	(	_	PUNCT	_	_	_	_	_	_
100	d	_	X	_	Number=Sing	_	_	_	_
101	)	_	PUNCT	_	_	_	_	_	_
102	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
103	novel	_	NOUN	_	Number=Sing	_	_	_	_
104	,	_	PUNCT	_	_	_	_	_	_
105	approximately	_	ADV	_	_	_	_	_	_
106	320	_	NUM	_	NumType=Card	_	_	_	_
107	-	_	PUNCT	_	_	_	_	_	_
108	kDa	_	NOUN	_	Number=Sing	_	_	_	_
109	species	_	NOUN	_	Number=Plur	_	_	_	_
110	of	_	ADP	_	_	_	_	_	_
111	ubiquitin	_	NOUN	_	Number=Sing	_	_	_	_
112	-	_	PUNCT	_	_	_	_	_	_
113	protein	_	NOUN	_	Number=Sing	_	_	_	_
114	ligase	_	NOUN	_	Number=Sing	_	_	_	_
115	,	_	PUNCT	_	_	_	_	_	_
116	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
117	involved	_	ADJ	_	Degree=Pos	_	_	_	_
118	in	_	ADP	_	_	_	_	_	_
119	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
120	process	_	NOUN	_	Number=Sing	_	_	_	_
121	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	distinct	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	E6	_	PROPN	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	p53-conjugating	_	NOUN	_	Degree=Pos	_	_	_	_
13	ligase	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	E3	_	PROPN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	"	_	PUNCT	_	_	_	_	_	_
22	N	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	end	_	NOUN	_	Number=Sing	_	_	_	_
25	rule	_	NOUN	_	Number=Sing	_	_	_	_
26	"	_	PUNCT	_	_	_	_	_	_
27	ligase	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012586	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
6	directs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	tissue	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	specific	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
14	colony	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
3	colony	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	M	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CSF	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	tissue	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	fashion	_	NOUN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	two	_	NUM	_	NumType=Card	_	_	_	_
23	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
24	promoters	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	placenta	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	order	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	further	_	ADV	_	_	_	_	_	_
5	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	commitment	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	multipotential	_	ADJ	_	Degree=Pos	_	_	_	_
18	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
24	lineage	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
27	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	investigation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	factors	_	NOUN	_	Number=Plur	_	_	_	_
34	which	_	PRON	_	PronType=Rel	_	_	_	_
35	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	M	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	CSF	_	NOUN	_	Number=Sing	_	_	_	_
40	receptor	_	NOUN	_	Number=Sing	_	_	_	_
41	very	_	ADV	_	_	_	_	_	_
42	early	_	ADV	_	Degree=Pos	_	_	_	_
43	during	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
46	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
47	process	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
8	M	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	CSF	_	PROPN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	directs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	reporter	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	tissue	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	specific	_	ADJ	_	Degree=Pos	_	_	_	_
22	fashion	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	ADP	_	_	_	_	_	_
2	one	_	NUM	_	NumType=Card	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	few	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	monocyte	_	ADJ	_	Degree=Pos	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	B-cell	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_

1	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	whether	_	SCONJ	_	_	_	_	_	_
8	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
9	binds	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	M	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	CSF	_	NOUN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	both	_	DET	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	vitro	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	extracts	_	NOUN	_	Number=Plur	_	_	_	_
16	bind	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	M	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	CSF	_	PROPN	_	Number=Sing	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	just	_	ADV	_	_	_	_	_	_
29	upstream	_	ADV	_	Number=Sing	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	major	_	ADJ	_	Degree=Pos	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	initiation	_	NOUN	_	Number=Sing	_	_	_	_
35	site	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	site	_	NOUN	_	Number=Sing	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	eliminate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	PU.	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	binding	_	VERB	_	Degree=Pos	_	_	_	_
10	decrease	_	NOUN	_	Number=Sing	_	_	_	_
11	M	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	CSF	_	NOUN	_	Number=Sing	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	significantly	_	ADV	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	lines	_	NOUN	_	Number=Plur	_	_	_	_
22	only	_	ADV	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	PU.	_	PROPN	_	Number=Sing	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	transactivates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	M	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	CSF	_	NOUN	_	Number=Sing	_	_	_	_
10	receptor	_	NOUN	_	Number=Sing	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	nonmacrophage	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	PU.	_	PROPN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	major	_	ADJ	_	Degree=Pos	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	development	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	SCONJ	_	_	_	_	_	_
18	directing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	key	_	ADJ	_	Degree=Pos	_	_	_	_
27	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
28	growth	_	NOUN	_	Number=Sing	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012588	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	severe	_	ADJ	_	Degree=Pos	_	_	_	_
3	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	females	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	tiny	_	ADJ	_	Degree=Pos	_	_	_	_
8	ring	_	NOUN	_	Number=Sing	_	_	_	_
9	X	_	NOUN	_	_	_	_	_	_
10	chromosomes	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	inability	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
17	chromosomes	_	NOUN	_	Number=Plur	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	undergo	_	VERB	_	VerbForm=Inf	_	_	_	_
20	X	_	ADP	_	_	_	_	_	_
21	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Mental	_	ADJ	_	Degree=Pos	_	_	_	_
2	retardation	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	constellation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	congenital	_	ADJ	_	Degree=Pos	_	_	_	_
8	malformations	_	NOUN	_	Number=Plur	_	_	_	_
9	not	_	ADV	_	_	_	_	_	_
10	usually	_	ADV	_	_	_	_	_	_
11	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	Turner	_	PROPN	_	Number=Sing	_	_	_	_
14	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	some	_	DET	_	_	_	_	_	_
19	females	_	NOUN	_	Number=Plur	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	mosaic	_	NOUN	_	Number=Sing	_	_	_	_
23	45	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	X	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	46	_	NUM	_	NumType=Card	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	X	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	r	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	X	_	NOUN	_	Number=Sing	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	karyotype	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	females	_	NOUN	_	Number=Plur	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	XIST	_	NOUN	_	Number=Sing	_	_	_	_
9	locus	_	NOUN	_	Number=Sing	_	_	_	_
10	on	_	ADP	_	_	_	_	_	_
11	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	tiny	_	ADJ	_	Degree=Pos	_	_	_	_
13	ring	_	NOUN	_	Number=Sing	_	_	_	_
14	X	_	NOUN	_	_	_	_	_	_
15	chromosomes	_	NOUN	_	Number=Plur	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	either	_	CCONJ	_	_	_	_	_	_
18	not	_	PART	_	_	_	_	_	_
19	present	_	ADJ	_	Degree=Pos	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	XIST	_	NOUN	_	Number=Sing	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	well	_	ADV	_	Degree=Pos	_	_	_	_
6	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	X	_	NOUN	_	Number=Sing	_	_	_	_
12	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	female	_	ADJ	_	Degree=Pos	_	_	_	_
15	somatic	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	spermatogonia	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	nonexpression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	locus	_	NOUN	_	Number=Sing	_	_	_	_
24	even	_	ADV	_	_	_	_	_	_
25	when	_	ADV	_	PronType=Int	_	_	_	_
26	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	present	_	ADJ	_	Degree=Pos	_	_	_	_
29	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	that	_	SCONJ	_	_	_	_	_	_
31	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
32	chromosomes	_	NOUN	_	Number=Plur	_	_	_	_
33	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	transcriptionally	_	ADV	_	_	_	_	_	_
35	active	_	ADJ	_	Degree=Pos	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	ring	_	NOUN	_	Number=Sing	_	_	_	_
8	X	_	SYM	_	_	_	_	_	_
9	chromosomes	_	NOUN	_	Number=Plur	_	_	_	_
10	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
11	XIST	_	PROPN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	XISTE	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	three	_	NUM	_	NumType=Card	_	_	_	_
20	females	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	severe	_	ADJ	_	Degree=Pos	_	_	_	_
23	phenotypes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	tiny	_	ADJ	_	Degree=Pos	_	_	_	_
4	ring	_	NOUN	_	Number=Sing	_	_	_	_
5	X	_	NOUN	_	_	_	_	_	_
6	chromosomes	_	NOUN	_	Number=Plur	_	_	_	_
7	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	antibody	_	NOUN	_	Number=Sing	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	acetylated	_	ADJ	_	Degree=Pos	_	_	_	_
15	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	histone	_	NOUN	_	Number=Sing	_	_	_	_
18	H4	_	NUM	_	Number=Sing	_	_	_	_
19	marking	_	NOUN	_	VerbForm=Ger	_	_	_	_
20	transcribed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	chromatin	_	NOUN	_	Number=Sing	_	_	_	_
22	domains	_	NOUN	_	Number=Plur	_	_	_	_
23	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	labeled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	at	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	level	_	NOUN	_	Number=Sing	_	_	_	_
28	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
29	with	_	SCONJ	_	_	_	_	_	_
30	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	being	_	AUX	_	VerbForm=Ger	_	_	_	_
32	active	_	ADJ	_	Degree=Pos	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	tow	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	XISTE	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	ring	_	NOUN	_	Number=Sing	_	_	_	_
10	chromosomes	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
13	whether	_	SCONJ	_	_	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	normally	_	ADV	_	_	_	_	_	_
18	silent	_	ADJ	_	Degree=Pos	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	inactive	_	ADJ	_	Number=Sing	_	_	_	_
22	X	_	NOUN	_	Number=Sing	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
27	chromosomes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Analyses	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	TIMP	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	ZXDA	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	ZXDB	_	ADJ	_	Number=Sing	_	_	_	_
13	loci	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
17	short	_	ADJ	_	Degree=Pos	_	_	_	_
18	arm	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	AR	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	PHKA1	_	NOUN	_	Number=Sing	_	_	_	_
24	loci	_	NOUN	_	Number=Sing	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	long	_	ADJ	_	Degree=Pos	_	_	_	_
28	arm	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	well	_	ADV	_	Degree=Pos	_	_	_	_
32	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	from	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	tiny	_	ADJ	_	Degree=Pos	_	_	_	_
36	ring	_	NOUN	_	Number=Sing	_	_	_	_
37	X	_	NOUN	_	_	_	_	_	_
38	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
39	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
40	XIST	_	NOUN	_	Number=Sing	_	_	_	_
41	DNA	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	ring	_	NOUN	_	Number=Sing	_	_	_	_
5	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	XIST	_	NOUN	_	Tense=Past|VerbForm=Part	_	_	_	_
9	DNA	_	NOUN	_	Number=Sing	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	transcribe	_	VERB	_	VerbForm=Inf	_	_	_	_
14	it	_	PRON	_	Case=Acc|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
15	show	_	VERB	_	VerbForm=Inf	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	AR	_	NOUN	_	Number=Sing	_	_	_	_
19	allele	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	along	_	ADP	_	_	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	one	_	NUM	_	NumType=Card	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	normal	_	ADJ	_	Degree=Pos	_	_	_	_
29	X	_	NOUN	_	_	_	_	_	_
30	allele	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	0030012605	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Various	_	ADJ	_	Degree=Pos	_	_	_	_
2	modes	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	basic	_	ADJ	_	Degree=Pos	_	_	_	_
5	helix	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	loop	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	helix	_	NOUN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	regulation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	murine	_	ADJ	_	Number=Sing	_	_	_	_
16	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	lines	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcriptionally	_	ADV	_	_	_	_	_	_
3	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	regions	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	lymphomagenic	_	PROPN	_	Number=Sing	_	_	_	_
8	Akv	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	SL3	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	murine	_	NOUN	_	Number=Sing	_	_	_	_
14	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
15	retroviruses	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	MLVs	_	NOUN	_	Number=Plur	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	two	_	NUM	_	NumType=Card	_	_	_	_
21	types	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	E	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	box	_	NOUN	_	Number=Sing	_	_	_	_
26	consensus	_	NOUN	_	Number=Sing	_	_	_	_
27	motifs	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	CAGATG	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	type	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	EA	_	PROPN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	S	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	region	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	E	_	PROPN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	gre	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	tandem	_	NOUN	_	Number=Sing	_	_	_	_
30	repeat	_	VERB	_	Number=Sing	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
33	properties	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	requirements	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	individual	_	ADJ	_	Degree=Pos	_	_	_	_
9	E-boxes	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	MLV	_	NOUN	_	Number=Sing	_	_	_	_
12	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
13	regulation	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	only	_	ADV	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	E(gre	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	complexes	_	NOUN	_	Number=Plur	_	_	_	_
14	included	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	ALF1	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	HEB	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	E2A	_	PROPN	_	Number=Sing	_	_	_	_
20	basic	_	ADJ	_	Degree=Pos	_	_	_	_
21	helix	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	loop	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	helix	_	NOUN	_	Number=Sing	_	_	_	_
26	proteins	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Ectopic	_	PROPN	_	Degree=Pos	_	_	_	_
2	ALF1	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	E2A	_	NOUN	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	intact	_	NOUN	_	Number=Sing	_	_	_	_
8	E	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	gre	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	motifs	_	NOUN	_	Number=Plur	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	ALF1	_	DET	_	_	_	_	_	_
2	transactivated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Akv	_	PROPN	_	Number=Sing	_	_	_	_
6	MLV	_	NOUN	_	Number=Sing	_	_	_	_
7	through	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	E(gre	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	motifs	_	NOUN	_	Number=Plur	_	_	_	_
13	equally	_	ADV	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	whereas	_	SCONJ	_	_	_	_	_	_
16	E2A	_	PROPN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	required	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
23	E	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	gre	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	motif	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	T-	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	B-cell	_	NOUN	_	Number=Sing	_	_	_	_
5	lines	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	E	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	gre	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	motifs	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	major	_	ADJ	_	Degree=Pos	_	_	_	_
16	importance	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	Akv	_	ADJ	_	Number=Sing	_	_	_	_
19	MLV	_	PROPN	_	Number=Sing	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	while	_	SCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	EA	_	PROPN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	S	_	PROPN	_	Number=Sing	_	_	_	_
28	motif	_	NOUN	_	Number=Sing	_	_	_	_
29	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	some	_	DET	_	_	_	_	_	_
31	effect	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	neither	_	CCONJ	_	_	_	_	_	_
5	E	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	gre	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	nor	_	CCONJ	_	_	_	_	_	_
10	EA	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	S	_	PROPN	_	Number=Sing	_	_	_	_
13	motifs	_	NOUN	_	Number=Plur	_	_	_	_
14	contributed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	pronouncedly	_	ADV	_	_	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	Akv	_	VERB	_	Number=Sing	_	_	_	_
18	MLV	_	NOUN	_	Number=Sing	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	NIH	_	PROPN	_	Number=Sing	_	_	_	_
22	3T3	_	NUM	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
25	DNA	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	binding	_	VERB	_	Number=Sing	_	_	_	_
28	ALF1	_	NOUN	_	Number=Sing	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	HEB	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	E2A	_	NOUN	_	Number=Sing	_	_	_	_
33	proteins	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Id1	_	PROPN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	repress	_	VERB	_	VerbForm=Inf	_	_	_	_
8	ALF1	_	PROPN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	vitro	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vivo	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
4	Id1	_	PROPN	_	Number=Sing	_	_	_	_
5	repressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	E	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	gre	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	EA	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	S	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	MLV	_	NOUN	_	Number=Sing	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	lines	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	E	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	gre	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	motifs	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	interacting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	basic	_	ADJ	_	Degree=Pos	_	_	_	_
12	helix	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	loop	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	helix	_	NOUN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	important	_	ADJ	_	Degree=Pos	_	_	_	_
20	determinants	_	NOUN	_	Number=Plur	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	MLV	_	NOUN	_	Number=Sing	_	_	_	_
23	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	lines	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012607	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	4	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	type	_	NOUN	_	Number=Sing	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	II	_	NUM	_	NumType=Card	_	_	_	_
19	interferons	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Th2	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	4	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	4	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	13	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	13	_	NUM	_	NumType=Card	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	induce	_	VERB	_	Degree=Pos	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
30	subset	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	human	_	ADJ	_	Degree=Pos	_	_	_	_
35	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	including	_	VERB	_	VerbForm=Ger	_	_	_	_
38	FcepsilonRIIb	_	PROPN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	CD23	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	15	_	NUM	_	NumType=Card	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	lipoxygenase	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	IL	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	1	_	NUM	_	NumType=Card	_	_	_	_
50	receptor	_	NOUN	_	Number=Sing	_	_	_	_
51	antagonist	_	PROPN	_	Number=Sing	_	_	_	_
52	(	_	PUNCT	_	_	_	_	_	_
53	IL	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	1ra	_	PROPN	_	Number=Sing	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	and	_	CCONJ	_	_	_	_	_	_
59	type	_	NOUN	_	Number=Sing	_	_	_	_
60	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
61	and	_	CCONJ	_	_	_	_	_	_
62	type	_	NOUN	_	Number=Sing	_	_	_	_
63	II	_	NUM	_	NumType=Card	_	_	_	_
64	IL	_	PROPN	_	Number=Sing	_	_	_	_
65	-	_	PUNCT	_	_	_	_	_	_
66	1	_	NUM	_	NumType=Card	_	_	_	_
67	receptors	_	NOUN	_	Number=Plur	_	_	_	_
68	(	_	PUNCT	_	_	_	_	_	_
69	IL	_	PROPN	_	Number=Sing	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	1R	_	NUM	_	NumType=Card	_	_	_	_
72	)	_	PUNCT	_	_	_	_	_	_
73	.	_	PUNCT	_	_	_	_	_	_

1	Type	_	NOUN	_	Number=Sing	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	interferons	_	VERB	_	Number=Plur	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	IFN	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	type	_	NOUN	_	Number=Sing	_	_	_	_
15	II	_	NUM	_	NumType=Card	_	_	_	_
16	interferon	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	IFN	_	ADJ	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	gamma	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	inhibit	_	VERB	_	Number=Sing	_	_	_	_
23	induction	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	4	_	NUM	_	NumType=Card	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	13	_	NUM	_	NumType=Card	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	IFNs	_	PROPN	_	Number=Plur	_	_	_	_
8	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	overview	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	discuss	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	signal	_	NOUN	_	Number=Sing	_	_	_	_
17	transducer	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	activator	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	6	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	in	_	SCONJ	_	_	_	_	_	_
26	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	4	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	13	_	NUM	_	NumType=Card	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	gene	_	NOUN	_	Number=Sing	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	discuss	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	recent	_	ADJ	_	Degree=Pos	_	_	_	_
6	findings	_	NOUN	_	Number=Plur	_	_	_	_
7	that	_	DET	_	PronType=Rel	_	_	_	_
8	type	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	type	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	II	_	NUM	_	NumType=Card	_	_	_	_
13	IFNs	_	PROPN	_	Number=Plur	_	_	_	_
14	suppress	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	4/IL	_	NUM	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	13	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	SCONJ	_	_	_	_	_	_
25	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
27	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
30	translocation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	STAT6	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	type	_	NOUN	_	Number=Sing	_	_	_	_
5	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	type	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	II	_	NUM	_	NumType=Card	_	_	_	_
9	IFNs	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	4/IL	_	NUM	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	13	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	STAT6	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	dose	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	time	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	not	_	PART	_	_	_	_	_	_
32	unique	_	ADJ	_	Degree=Pos	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	because	_	SCONJ	_	_	_	_	_	_
36	IFNs	_	NOUN	_	Number=Plur	_	_	_	_
37	induce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	same	_	ADJ	_	Degree=Pos	_	_	_	_
40	effects	_	NOUN	_	Number=Plur	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	evident	_	ADJ	_	Degree=Pos	_	_	_	_
8	unless	_	SCONJ	_	_	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	preincubated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	IFN	_	PROPN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	at	_	ADV	_	_	_	_	_	_
16	least	_	ADV	_	Degree=Sup	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	h	_	NOUN	_	Number=Sing	_	_	_	_
19	before	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	4	_	NUM	_	NumType=Card	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	can	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	actinomycin	_	NOUN	_	Number=Sing	_	_	_	_
9	D	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	requirement	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	de	_	PROPN	_	Number=Sing	_	_	_	_
16	novo	_	PROPN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	model	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	which	_	DET	_	PronType=Rel	_	_	_	_
7	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	IFN	_	PROPN	_	Number=Sing	_	_	_	_
12	activates	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	de	_	VERB	_	Number=Sing	_	_	_	_
14	novo	_	PROPN	_	Number=Sing	_	_	_	_
15	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	possibly	_	ADV	_	_	_	_	_	_
22	one	_	NUM	_	NumType=Card	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	more	_	ADJ	_	Degree=Cmp	_	_	_	_
25	members	_	NOUN	_	Number=Plur	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	SOCS	_	NOUN	_	Number=Plur	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	SSI	_	NOUN	_	Number=Sing	_	_	_	_
31	/	_	PUNCT	_	_	_	_	_	_
32	CIS	_	PROPN	_	Number=Sing	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	family	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	capable	_	ADJ	_	Degree=Pos	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	suppressing	_	VERB	_	VerbForm=Ger	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
42	by	_	ADP	_	_	_	_	_	_
43	IL	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	4	_	NUM	_	NumType=Card	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	IL	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	13	_	NUM	_	NumType=Card	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	essential	_	ADJ	_	Degree=Pos	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	4/IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	13-induced	_	ADJ	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	ability	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	IFN	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	beta	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	IFN	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	gamma	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
29	STAT6	_	PROPN	_	Number=Sing	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	explanation	_	NOUN	_	Number=Sing	_	_	_	_
34	for	_	ADP	_	_	_	_	_	_
35	how	_	ADV	_	PronType=Int	_	_	_	_
36	IFNs	_	PROPN	_	Number=Plur	_	_	_	_
37	can	_	AUX	_	VerbForm=Fin	_	_	_	_
38	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	4/IL	_	NUM	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	13	_	NUM	_	NumType=Card	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
46	gene	_	NOUN	_	Number=Sing	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012611	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Positive	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	negative	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	2	_	NUM	_	NumType=Card	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	_	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
12	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	process	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
24	expansion	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	displays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	both	_	CCONJ	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	:	_	PUNCT	_	_	_	_	_	_
15	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	only	_	ADV	_	_	_	_	_	_
18	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	CD4	_	PROPN	_	Number=Sing	_	_	_	_
21	+	_	SYM	_	_	_	_	_	_

1	T	_	NUM	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	after	_	ADP	_	_	_	_	_	_
4	antigenic	_	ADJ	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
7	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	cis	_	NOUN	_	Number=Plur	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
5	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	sites	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	after	_	ADP	_	_	_	_	_	_
18	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	analysed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	function	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
12	cis	_	NOUN	_	Number=Plur	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	context	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	native	_	ADJ	_	Degree=Pos	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	sequence	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	276	_	NUM	_	NumType=Card	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	261	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	distal	_	ADJ	_	Degree=Pos	_	_	_	_
20	octamer	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	256	_	NUM	_	NumType=Card	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	248	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
31	octamer	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	-	_	SYM	_	_	_	_	_	_
34	75	_	NUM	_	NumType=Card	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	-	_	SYM	_	_	_	_	_	_
37	66	_	NUM	_	NumType=Card	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	sites	_	NOUN	_	Number=Plur	_	_	_	_
40	not	_	ADV	_	_	_	_	_	_
41	only	_	ADV	_	_	_	_	_	_
42	act	_	VERB	_	VerbForm=Inf	_	_	_	_
43	as	_	ADP	_	_	_	_	_	_
44	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	IL	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	2	_	NUM	_	NumType=Card	_	_	_	_
49	gene	_	NOUN	_	Number=Sing	_	_	_	_
50	transcription	_	NOUN	_	Number=Sing	_	_	_	_
51	in	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	presence	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
56	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	but	_	CCONJ	_	_	_	_	_	_
59	also	_	ADV	_	_	_	_	_	_
60	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
61	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
62	silencing	_	NOUN	_	Degree=Pos	_	_	_	_
63	effect	_	NOUN	_	Number=Sing	_	_	_	_
64	on	_	ADP	_	_	_	_	_	_
65	IL	_	PROPN	_	Number=Sing	_	_	_	_
66	-	_	PUNCT	_	_	_	_	_	_
67	2	_	NUM	_	NumType=Card	_	_	_	_
68	gene	_	NOUN	_	Number=Sing	_	_	_	_
69	expression	_	NOUN	_	Number=Sing	_	_	_	_
70	in	_	ADP	_	_	_	_	_	_
71	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
72	cells	_	NOUN	_	Number=Plur	_	_	_	_
73	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	sites	_	NOUN	_	Number=Plur	_	_	_	_
4	display	_	VERB	_	_	_	_	_	_
5	disparate	_	ADJ	_	Degree=Pos	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	different	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lines	_	NOUN	_	Number=Plur	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	distal	_	ADJ	_	Degree=Pos	_	_	_	_
22	purine	_	NOUN	_	Number=Sing	_	_	_	_
23	box	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	291	_	NUM	_	NumType=Card	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	-	_	SYM	_	_	_	_	_	_
29	277	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
34	purine	_	NOUN	_	Number=Sing	_	_	_	_
35	box	_	NOUN	_	Number=Sing	_	_	_	_
36	sites	_	NOUN	_	Number=Plur	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	-	_	SYM	_	_	_	_	_	_
39	145	_	NUM	_	NumType=Card	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	-	_	SYM	_	_	_	_	_	_
42	128	_	NUM	_	NumType=Card	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	AP	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	186	_	NUM	_	NumType=Card	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	176	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	206	_	NUM	_	NumType=Card	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	-	_	SYM	_	_	_	_	_	_
24	195	_	NUM	_	NumType=Card	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	different	_	ADJ	_	Degree=Pos	_	_	_	_
29	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	EL4	_	PROPN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	AP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	mediated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	response	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	PMA	_	PROPN	_	Number=Sing	_	_	_	_
11	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
12	while	_	SCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	PROPN	_	Number=Sing	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	responded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	complex	_	ADJ	_	Degree=Pos	_	_	_	_
16	process	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
19	cis	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	sites	_	NOUN	_	Number=Plur	_	_	_	_
24	interact	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	exert	_	VERB	_	VerbForm=Inf	_	_	_	_
27	different	_	ADJ	_	Degree=Pos	_	_	_	_
28	effects	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	T	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	representative	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
35	stages	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012613	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	elements	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	requirements	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	primary	_	ADJ	_	Degree=Pos	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Prior	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	several	_	ADJ	_	Degree=Pos	_	_	_	_
6	elements	_	NOUN	_	Number=Plur	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	contribute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	sites	_	NOUN	_	Number=Plur	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
5	corresponding	_	ADJ	_	Degree=Pos	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	:	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	AP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	OCT	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	SYM	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	AT	_	ADP	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	latter	_	ADJ	_	Degree=Pos	_	_	_	_
3	"	_	PUNCT	_	_	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	"	_	PUNCT	_	_	_	_	_	_
11	likely	_	ADV	_	_	_	_	_	_
12	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	tissue	_	NOUN	_	Number=Sing	_	_	_	_
16	specificity	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	primary	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	blood	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	verify	_	VERB	_	VerbForm=Inf	_	_	_	_
22	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	presence	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	physiologic	_	NOUN	_	Degree=Pos	_	_	_	_
27	setting	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	signals	_	NOUN	_	Number=Plur	_	_	_	_
33	that	_	PRON	_	PronType=Rel	_	_	_	_
34	stimulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	activity	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	upon	_	ADP	_	_	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	not	_	ADV	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	growth	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	signaling	_	NOUN	_	Number=Sing	_	_	_	_
5	requirements	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	protein	_	VERB	_	VerbForm=Inf	_	_	_	_
10	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
11	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
12	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	considerably	_	ADV	_	_	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Only	_	ADV	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	activities	_	NOUN	_	Number=Plur	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	AT	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	require	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	two	_	NUM	_	NumType=Card	_	_	_	_
15	signals	_	NOUN	_	Number=Plur	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	i.e.	_	X	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	PMA	_	PROPN	_	Number=Sing	_	_	_	_
23	plus	_	CCONJ	_	_	_	_	_	_
24	either	_	CCONJ	_	_	_	_	_	_
25	lectin	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	antibody	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	CD3	_	PROPN	_	Number=Sing	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	CD28	_	PROPN	_	Number=Sing	_	_	_	_
33	surface	_	NOUN	_	Number=Sing	_	_	_	_
34	molecules	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Other	_	ADJ	_	Degree=Pos	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	lectin	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	antibody	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	PMA	_	NOUN	_	Number=Sing	_	_	_	_
14	alone	_	ADV	_	_	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	After	_	ADP	_	_	_	_	_	_
2	appropriate	_	ADJ	_	Degree=Pos	_	_	_	_
3	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	both	_	CCONJ	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	AT	_	ADP	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	peculiarly	_	ADV	_	_	_	_	_	_
15	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
20	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
21	anisomycin	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	correlate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	AT	_	ADP	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	gel	_	NOUN	_	Number=Sing	_	_	_	_
16	shift	_	NOUN	_	Number=Sing	_	_	_	_
17	assays	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	two	_	NUM	_	NumType=Card	_	_	_	_
21	signals	_	NOUN	_	Number=Plur	_	_	_	_
22	requirements	_	NOUN	_	Number=Plur	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012617	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cytokine	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	modulating	_	VERB	_	Number=Sing	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	tepoxalin	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	new	_	ADJ	_	Degree=Pos	_	_	_	_
10	potential	_	ADJ	_	Degree=Pos	_	_	_	_
11	antirheumatic	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Tepoxalin	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	new	_	ADJ	_	Degree=Pos	_	_	_	_
5	dual	_	ADJ	_	Degree=Pos	_	_	_	_
6	cyclooxygenase	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	lipoxygenase	_	NOUN	_	Number=Sing	_	_	_	_
11	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	compound	_	NOUN	_	Number=Sing	_	_	_	_
13	currently	_	ADV	_	_	_	_	_	_
14	under	_	ADP	_	_	_	_	_	_
15	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
16	investigation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	possess	_	VERB	_	VerbForm=Inf	_	_	_	_
7	anti-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	variety	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	animal	_	NOUN	_	Number=Sing	_	_	_	_
14	models	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	more	_	ADV	_	_	_	_	_	_
17	recently	_	ADV	_	_	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	signal	_	NOUN	_	Number=Sing	_	_	_	_
25	transduction	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	current	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	conducted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	evaluate	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	modulating	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	tepoxalin	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	role	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	iron	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	effects	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
4	blood	_	NOUN	_	Number=Sing	_	_	_	_
5	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	OKT3	_	PROPN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	PMA	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	tepoxalin	_	NOUN	_	Number=Sing	_	_	_	_
17	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	IC50	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	6	_	NUM	_	NumType=Card	_	_	_	_
25	microM	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	production	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	LTB4	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	IC50	_	NUM	_	Number=Sing	_	_	_	_
11	=	_	SYM	_	_	_	_	_	_
12	0.5	_	NUM	_	NumType=Card	_	_	_	_
13	microM	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	6	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	TNF	_	PROPN	_	Number=Sing	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	IC50	_	PROPN	_	Number=Sing	_	_	_	_
30	=	_	PUNCT	_	_	_	_	_	_
31	10	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	SYM	_	_	_	_	_	_
33	12	_	NUM	_	NumType=Card	_	_	_	_
34	microM	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	Add	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	back	_	NOUN	_	Number=Sing	_	_	_	_
4	experiments	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	either	_	CCONJ	_	_	_	_	_	_
7	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	6	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	LTB4	_	PROPN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	conditioned	_	VERB	_	Degree=Pos	_	_	_	_
21	media	_	NOUN	_	Number=Sing	_	_	_	_
22	failed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	restore	_	VERB	_	VerbForm=Inf	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
27	response	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	presence	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	tepoxalin	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	concurrent	_	ADJ	_	Degree=Pos	_	_	_	_
5	addition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	iron	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	form	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	ferrous	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	ferric	_	NOUN	_	Number=Sing	_	_	_	_
16	chloride	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	iron	_	ADJ	_	Degree=Pos	_	_	_	_
20	salts	_	NOUN	_	Number=Plur	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	reversed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
27	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	tepoxalin	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Tepoxalin	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	kappa	_	PROPN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	several	_	ADJ	_	Degree=Pos	_	_	_	_
18	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Tepoxalin	_	PROPN	_	Number=Sing	_	_	_	_
2	's	_	PART	_	_	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	kappa	_	PROPN	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	reversed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	addition	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	iron	_	ADJ	_	Number=Sing	_	_	_	_
16	salts	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	action	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	tepoxalin	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
11	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	PBMC	_	PROPN	_	Number=Sing	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	at	_	ADV	_	_	_	_	_	_
17	least	_	ADV	_	Degree=Sup	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	part	_	NOUN	_	Number=Sing	_	_	_	_
20	due	_	ADP	_	_	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	ability	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	reduce	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	amount	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	available	_	ADJ	_	Degree=Pos	_	_	_	_
30	iron	_	NOUN	_	Number=Sing	_	_	_	_
31	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
41	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
44	production	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012618	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Role	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	X2	_	PROPN	_	Number=Sing	_	_	_	_
5	box	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	DRA	_	PROPN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	function	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	evolutionary	_	ADJ	_	Degree=Pos	_	_	_	_
8	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	X2	_	PROPN	_	Number=Sing	_	_	_	_
10	box	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	HLA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	DRA	_	PROPN	_	Number=Sing	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	major	_	ADJ	_	Degree=Pos	_	_	_	_
24	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
25	complex	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	MHC	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	in	_	SCONJ	_	_	_	_	_	_
30	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	B	_	ADJ	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	X2	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	members	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1/ATF	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	CREB	_	NOUN	_	Number=Sing	_	_	_	_
15	families	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	X2	_	NOUN	_	Number=Sing	_	_	_	_
24	box	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	5'-	_	NUM	_	NumType=Card	_	_	_	_
27	TGCGTCA	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	3	_	NUM	_	NumType=Card	_	_	_	_
30	'	_	PUNCT	_	_	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	from	_	ADP	_	_	_	_	_	_
33	positions	_	NOUN	_	Number=Plur	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	97	_	NUM	_	NumType=Card	_	_	_	_
36	to	_	ADP	_	_	_	_	_	_
37	-	_	SYM	_	_	_	_	_	_
38	91	_	NUM	_	NumType=Card	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	DRA	_	PROPN	_	Number=Sing	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	In	_	SCONJ	_	_	_	_	_	_
2	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
3	Raji	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	little	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	no	_	DET	_	_	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	X2	_	PROPN	_	Number=Sing	_	_	_	_
13	box	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	sharp	_	ADJ	_	Degree=Pos	_	_	_	_
3	contrast	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	B	_	ADJ	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
12	ester	_	NOUN	_	Number=Sing	_	_	_	_
13	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	13	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	acetate	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	TPA	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	strong	_	ADJ	_	Degree=Pos	_	_	_	_
23	interactions	_	NOUN	_	Number=Plur	_	_	_	_
24	between	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	X2	_	PROPN	_	Number=Sing	_	_	_	_
27	box	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	X2	_	PROPN	_	Number=Sing	_	_	_	_
32	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
33	c	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	Fos	_	NOUN	_	Number=Sing	_	_	_	_
36	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	transient	_	ADJ	_	Degree=Pos	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	RNA	_	PROPN	_	Number=Sing	_	_	_	_
8	analyses	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	kinase	_	NOUN	_	Number=Sing	_	_	_	_
15	C	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	PKC	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	rates	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	from	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	wild	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	type	_	NOUN	_	Number=Sing	_	_	_	_
29	DRA	_	NOUN	_	Number=Sing	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	but	_	CCONJ	_	_	_	_	_	_
32	not	_	ADV	_	_	_	_	_	_
33	from	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	DRA	_	NOUN	_	Number=Sing	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
38	clustered	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
39	point	_	NOUN	_	Number=Sing	_	_	_	_
40	mutations	_	NOUN	_	Number=Plur	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	X2	_	NOUN	_	Number=Sing	_	_	_	_
44	box	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	co-expression	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
7	negative	_	ADJ	_	Degree=Pos	_	_	_	_
8	c-Fos	_	NOUN	_	Number=Sing	_	_	_	_
9	abolished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	TPA	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	DRA	_	PROPN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	interactions	_	NOUN	_	Number=Plur	_	_	_	_
27	between	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	X2	_	PROPN	_	Number=Sing	_	_	_	_
30	box	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	X2	_	PROPN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	which	_	PRON	_	PronType=Rel	_	_	_	_
37	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	c-Fos	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012624	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	genes	_	NOUN	_	Number=Plur	_	_	_	_
6	after	_	SCONJ	_	_	_	_	_	_
7	influenza	_	VERB	_	VerbForm=Ger	_	_	_	_
8	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	virus	_	NOUN	_	Number=Sing	_	_	_	_
10	infection	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Infection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	influenza	_	NOUN	_	Number=Sing	_	_	_	_
7	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	broad	_	ADJ	_	Degree=Pos	_	_	_	_
12	range	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	attracting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	chemokines	_	NOUN	_	Number=Plur	_	_	_	_
21	before	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	undergo	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	underlying	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	corresponding	_	VERB	_	Degree=Pos	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	transcriptionally	_	ADV	_	_	_	_	_	_
11	initiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	infection	_	NOUN	_	Number=Sing	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	still	_	ADV	_	_	_	_	_	_
17	poorly	_	ADV	_	_	_	_	_	_
18	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_
6	B	_	PROPN	_	Number=Sing	_	_	_	_
7	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	play	_	VERB	_	VerbForm=Inf	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	important	_	ADJ	_	Degree=Pos	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	regulation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	many	_	ADJ	_	Degree=Pos	_	_	_	_
18	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
19	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	can	_	AUX	_	VerbForm=Fin	_	_	_	_
24	not	_	PART	_	_	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	only	_	ADJ	_	Degree=Pos	_	_	_	_
28	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	since	_	SCONJ	_	_	_	_	_	_
31	several	_	ADJ	_	Degree=Pos	_	_	_	_
32	cytokine	_	ADJ	_	Degree=Pos	_	_	_	_
33	genes	_	NOUN	_	Number=Plur	_	_	_	_
34	lack	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	respective	_	ADJ	_	Degree=Pos	_	_	_	_
36	binding	_	VERB	_	Number=Sing	_	_	_	_
37	sites	_	NOUN	_	Number=Plur	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
40	promoter	_	NOUN	_	Number=Sing	_	_	_	_
41	regions	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	additionally	_	ADV	_	_	_	_	_	_
5	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	possible	_	ADJ	_	Degree=Pos	_	_	_	_
11	importance	_	NOUN	_	Number=Sing	_	_	_	_
12	such	_	ADJ	_	Degree=Pos	_	_	_	_
13	as	_	ADP	_	_	_	_	_	_
14	CREB	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	CTF	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	OTF	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	OTF	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	explore	_	VERB	_	VerbForm=Inf	_	_	_	_
3	long	_	ADJ	_	Degree=Pos	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	term	_	NOUN	_	Number=Sing	_	_	_	_
6	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	may	_	AUX	_	VerbForm=Fin	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	important	_	ADJ	_	Degree=Pos	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	substitute	_	VERB	_	VerbForm=Inf	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	metabolized	_	VERB	_	Degree=Pos	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	proteins	_	NOUN	_	Number=Plur	_	_	_	_
32	after	_	ADP	_	_	_	_	_	_
33	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	differential	_	ADJ	_	Degree=Pos	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	:	_	PUNCT	_	_	_	_	_	_

1	CREB	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CTF	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	OTF	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	OFT	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	strongly	_	ADV	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	hours	_	NOUN	_	Number=Plur	_	_	_	_
26	after	_	SCONJ	_	_	_	_	_	_
27	influenza	_	NOUN	_	VerbForm=Ger	_	_	_	_
28	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	virus	_	NOUN	_	Number=Sing	_	_	_	_
30	infection	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	line	_	NOUN	_	Number=Sing	_	_	_	_
36	Mono	_	PROPN	_	Number=Sing	_	_	_	_
37	Mac	_	PROPN	_	Number=Sing	_	_	_	_
38	6	_	NUM	_	NumType=Card	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	while	_	SCONJ	_	_	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	freshly	_	ADV	_	_	_	_	_	_
43	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	human	_	ADJ	_	Degree=Pos	_	_	_	_
45	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
46	no	_	DET	_	_	_	_	_	_
47	significant	_	ADJ	_	Degree=Pos	_	_	_	_
48	changes	_	NOUN	_	Number=Plur	_	_	_	_
49	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
50	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	die	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	CREB	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	CTF	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	OTF	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	rather	_	ADV	_	_	_	_	_	_
23	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	8	_	NUM	_	NumType=Card	_	_	_	_
25	hours	_	NOUN	_	Number=Plur	_	_	_	_
26	after	_	ADP	_	_	_	_	_	_
27	infection	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	long	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	term	_	NOUN	_	Number=Sing	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	non-proliferating	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	minor	_	ADJ	_	Degree=Pos	_	_	_	_
22	importance	_	NOUN	_	Number=Sing	_	_	_	_
23	after	_	ADP	_	_	_	_	_	_
24	influenza	_	NOUN	_	Number=Sing	_	_	_	_
25	infection	_	NOUN	_	Number=Sing	_	_	_	_
26	since	_	SCONJ	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	apoptosisprone	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
32	availability	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	proteins	_	NOUN	_	Number=Plur	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012626	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	specific	_	ADJ	_	Degree=Pos	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	helix	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	loop	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	helix	_	NOUN	_	Number=Sing	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	encoded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	E2A	_	PROPN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	E2A	_	PROPN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	helix	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	loop	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	helix	_	NOUN	_	Number=Sing	_	_	_	_
14	family	_	NOUN	_	Number=Sing	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	specific	_	ADJ	_	Degree=Pos	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	part	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	dimeric	_	ADJ	_	Degree=Pos	_	_	_	_
28	complexes	_	NOUN	_	Number=Plur	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	E	_	NOUN	_	Number=Sing	_	_	_	_
33	box	_	NOUN	_	Number=Sing	_	_	_	_
34	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
35	elements	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	E2A	_	PROPN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	wide	_	ADJ	_	Degree=Pos	_	_	_	_
18	range	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	types	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	now	_	ADV	_	_	_	_	_	_
4	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	mouse	_	NOUN	_	Number=Sing	_	_	_	_
9	E2A	_	PROPN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	level	_	NOUN	_	Number=Sing	_	_	_	_
15	using	_	VERB	_	VerbForm=Ger	_	_	_	_
16	polyclonal	_	ADJ	_	Degree=Pos	_	_	_	_
17	antisera	_	NOUN	_	Number=Sing	_	_	_	_
18	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	against	_	ADP	_	_	_	_	_	_
20	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
21	portions	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	E2A	_	PROPN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	probe	_	VERB	_	VerbForm=Inf	_	_	_	_
28	blots	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
31	extracts	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	73	_	NUM	_	NumType=Card	_	_	_	_
3	kDa	_	NOUN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	analysis	_	NOUN	_	Number=Sing	_	_	_	_
10	:	_	PUNCT	_	_	_	_	_	_
11	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	highly	_	ADV	_	_	_	_	_	_
15	enriched	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lines	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	B	_	ADJ	_	Number=Sing	_	_	_	_
21	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
22	origin	_	NOUN	_	Number=Sing	_	_	_	_
23	as	_	SCONJ	_	_	_	_	_	_
24	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	pancreatic	_	ADJ	_	Degree=Pos	_	_	_	_
27	beta	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	fibroblast	_	ADJ	_	Degree=Pos	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	detection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	selectively	_	ADV	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	extracts	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	presence	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	E	_	NOUN	_	Number=Sing	_	_	_	_
19	box	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	LEF1	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	BCF1	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	;	_	PUNCT	_	_	_	_	_	_
30	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
31	binding	_	NOUN	_	Number=Sing	_	_	_	_
32	activity	_	NOUN	_	Number=Sing	_	_	_	_
33	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
34	previously	_	ADV	_	_	_	_	_	_
35	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	be	_	AUX	_	VerbForm=Inf	_	_	_	_
38	efficiently	_	ADV	_	_	_	_	_	_
39	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	antiserum	_	NOUN	_	Number=Sing	_	_	_	_
42	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	against	_	ADP	_	_	_	_	_	_
44	E2A	_	NOUN	_	Number=Sing	_	_	_	_
45	gene	_	NOUN	_	Number=Sing	_	_	_	_
46	products	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Transfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	full	_	ADJ	_	Degree=Pos	_	_	_	_
6	length	_	NOUN	_	Number=Sing	_	_	_	_
7	E2A	_	PROPN	_	Number=Sing	_	_	_	_
8	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
9	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	appearance	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	co-migrating	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	73	_	NUM	_	NumType=Card	_	_	_	_
18	kDa	_	NOUN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	SDS	_	NOUN	_	Number=Sing	_	_	_	_
22	gel	_	NOUN	_	Number=Sing	_	_	_	_
23	electrophoresis	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	co-migrating	_	VERB	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	LEF1	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	BCF1	_	NOUN	_	Number=Sing	_	_	_	_
30	on	_	ADP	_	_	_	_	_	_
31	mobility	_	NOUN	_	Number=Sing	_	_	_	_
32	shift	_	NOUN	_	Number=Sing	_	_	_	_
33	analysis	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	view	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	DNA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	LEF1	_	PROPN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	BCF1	_	PROPN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	E2A	_	NOUN	_	Number=Sing	_	_	_	_
22	proteins	_	NOUN	_	Number=Plur	_	_	_	_
23	;	_	PUNCT	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	selective	_	ADJ	_	Degree=Pos	_	_	_	_
26	appearance	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
29	putative	_	ADJ	_	Degree=Pos	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	specific	_	ADJ	_	Degree=Pos	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	factor	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	B	_	ADJ	_	Number=Sing	_	_	_	_
37	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	to	_	PART	_	_	_	_	_	_
41	be	_	AUX	_	VerbForm=Inf	_	_	_	_
42	attributable	_	ADJ	_	Degree=Pos	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	at	_	ADV	_	_	_	_	_	_
45	least	_	ADV	_	Degree=Sup	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	part	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	to	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
52	E2A	_	PROPN	_	Number=Sing	_	_	_	_
53	protein	_	NOUN	_	Number=Sing	_	_	_	_
54	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
57	cells	_	NOUN	_	Number=Plur	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012630	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inducible	_	ADJ	_	Degree=Pos	_	_	_	_
2	nitric	_	NOUN	_	Number=Sing	_	_	_	_
3	oxide	_	NOUN	_	Number=Sing	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
7	feedback	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
11	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Inducible	_	ADJ	_	Degree=Pos	_	_	_	_
2	nitric	_	ADJ	_	Number=Sing	_	_	_	_
3	oxide	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	iNO	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	sites	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
13	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	resident	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	nonresident	_	ADJ	_	Degree=Pos	_	_	_	_
18	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
19	wall	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
24	role	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	process	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	not	_	PART	_	_	_	_	_	_
31	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	novel	_	NOUN	_	Number=Sing	_	_	_	_
10	function	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	iNO	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	terminate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
17	processes	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	find	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	iNO	_	PROPN	_	Number=Sing	_	_	_	_
5	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	murine	_	NOUN	_	Number=Sing	_	_	_	_
8	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	like	_	ADP	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	RAW264.7	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	can	_	AUX	_	VerbForm=Fin	_	_	_	_
16	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
17	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	separated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	mixed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	endothelial	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	RAW264.7	_	NOUN	_	Number=Sing	_	_	_	_
31	coculture	_	NOUN	_	Number=Sing	_	_	_	_
32	system	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	iNO	_	PROPN	_	Number=Sing	_	_	_	_
3	production	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	endothelial	_	NOUN	_	Number=Sing	_	_	_	_
6	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	simultaneously	_	ADV	_	_	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
15	LPS	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	murine	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	IFN	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	gamma	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	iNO	_	PROPN	_	Number=Sing	_	_	_	_
4	synthase	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	iNOS	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	N	_	PROPN	_	Number=Sing	_	_	_	_
11	omega	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	monomethyl	_	PROPN	_	Number=Sing	_	_	_	_
14	-L	_	PUNCT	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	arginine	_	VERB	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	endothelial	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	RAW264.7	_	NOUN	_	Number=Sing	_	_	_	_
21	cocultures	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	murine	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	IFN	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	gamma	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	LPS	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	iNO	_	NOUN	_	Number=Sing	_	_	_	_
36	production	_	NOUN	_	Number=Sing	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	86	_	NUM	_	NumType=Card	_	_	_	_
39	%	_	SYM	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	augmented	_	VERB	_	Degree=Pos	_	_	_	_
42	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	iNOS	_	ADJ	_	Degree=Pos	_	_	_	_
47	expression	_	NOUN	_	Number=Sing	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	endothelial	_	NOUN	_	Number=Sing	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	RAW264.7	_	PROPN	_	Number=Sing	_	_	_	_
52	cells	_	NOUN	_	Number=Plur	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	respectively	_	ADV	_	_	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
58	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
59	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
60	to	_	ADP	_	_	_	_	_	_
61	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
62	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
63	cell	_	NOUN	_	Number=Sing	_	_	_	_
64	surface	_	NOUN	_	Number=Sing	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	transfection	_	NOUN	_	Number=Sing	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	using	_	VERB	_	VerbForm=Ger	_	_	_	_
5	various	_	ADJ	_	Degree=Pos	_	_	_	_
6	VCAM	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	constructs	_	NOUN	_	Number=Plur	_	_	_	_
11	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	that	_	SCONJ	_	_	_	_	_	_
13	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
14	effects	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	iNO	_	NOUN	_	Number=Sing	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	part	_	ADJ	_	Degree=Pos	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
31	effects	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	iNO	_	NOUN	_	Number=Sing	_	_	_	_
34	on	_	ADP	_	_	_	_	_	_
35	kappa	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	cis	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	acting	_	VERB	_	Number=Sing	_	_	_	_
40	elements	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Immunofluorescence	_	NOUN	_	Number=Sing	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	using	_	VERB	_	VerbForm=Ger	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	Ab	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	RelA	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	p65	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	subunit	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	iNO	_	PROPN	_	Number=Sing	_	_	_	_
22	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	iNO	_	PROPN	_	Number=Sing	_	_	_	_
6	attenuates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	iNOS	_	ADJ	_	Degree=Pos	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	inhibits	_	VERB	_	Degree=Pos	_	_	_	_
13	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
14	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	endothelial	_	VERB	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	endogenously	_	ADV	_	_	_	_	_	_
23	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	iNO	_	NOUN	_	_	_	_	_	_
25	may	_	AUX	_	VerbForm=Fin	_	_	_	_
26	be	_	AUX	_	VerbForm=Inf	_	_	_	_
27	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	important	_	ADJ	_	Degree=Pos	_	_	_	_
29	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
30	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
33	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012632	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	cytomegalovirus	_	NOUN	_	Number=Sing	_	_	_	_
3	binding	_	VERB	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	immunoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	continue	_	VERB	_	VerbForm=Inf	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	investigation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
8	events	_	NOUN	_	Number=Plur	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	occur	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	following	_	VERB	_	VerbForm=Ger	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	CMV	_	PROPN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	HCMV	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	infection	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	focused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	regulation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	following	_	VERB	_	VerbForm=Ger	_	_	_	_
28	viral	_	ADJ	_	Degree=Pos	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	First	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	viral	_	ADJ	_	Degree=Pos	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	number	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	immunoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1beta	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	A20	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	p105/p50	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	unactivated	_	ADJ	_	Degree=Pos	_	_	_	_
32	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	that	_	DET	_	_	_	_	_	_
35	neutralizing	_	VERB	_	VerbForm=Ger	_	_	_	_
36	Abs	_	NOUN	_	Number=Sing	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	major	_	ADJ	_	Degree=Pos	_	_	_	_
40	HCMV	_	PROPN	_	Number=Sing	_	_	_	_
41	glycoproteins	_	NOUN	_	Number=Plur	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	gB	_	PROPN	_	Number=Sing	_	_	_	_
44	(	_	PUNCT	_	_	_	_	_	_
45	UL55	_	NOUN	_	Number=Sing	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	gH	_	PROPN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	UL75	_	NOUN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
54	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
55	induction	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
58	genes	_	NOUN	_	Number=Plur	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Next	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	viral	_	ADJ	_	Degree=Pos	_	_	_	_
8	ligands	_	NOUN	_	Number=Plur	_	_	_	_
9	directly	_	ADV	_	_	_	_	_	_
10	up	_	ADP	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	monocyte	_	ADJ	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	upon	_	ADP	_	_	_	_	_	_
17	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	appropriate	_	ADJ	_	Degree=Pos	_	_	_	_
22	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
23	receptors	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	then	_	ADV	_	PronType=Dem	_	_	_	_
3	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	if	_	SCONJ	_	_	_	_	_	_
5	HCMV	_	PROPN	_	Number=Sing	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	translation	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	secretion	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	HCMV	_	PROPN	_	Number=Sing	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
9	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	release	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1beta	_	PROPN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	induced	_	VERB	_	Degree=Pos	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	products	_	NOUN	_	Number=Plur	_	_	_	_
6	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	NF	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	sites	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	regions	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	next	_	ADV	_	_	_	_	_	_
18	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	whether	_	SCONJ	_	_	_	_	_	_
20	there	_	PRON	_	_	_	_	_	_
21	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	up	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	regulation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
28	NF	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	levels	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	fact	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	translocated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
17	following	_	VERB	_	VerbForm=Ger	_	_	_	_
18	viral	_	ADJ	_	Degree=Pos	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	viral	_	ADJ	_	Degree=Pos	_	_	_	_
23	ligand	_	NOUN	_	Number=Sing	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Changes	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	changes	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	translocation	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Lastly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	p38	_	PROPN	_	Number=Sing	_	_	_	_
7	kinase	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	played	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	central	_	ADJ	_	Degree=Pos	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1beta	_	PROPN	_	Number=Sing	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	rapidly	_	ADV	_	_	_	_	_	_
23	up	_	ADV	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	following	_	VERB	_	VerbForm=Ger	_	_	_	_
27	infection	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
5	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	HCMV	_	PROPN	_	Number=Sing	_	_	_	_
8	initiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	signal	_	ADJ	_	Number=Sing	_	_	_	_
11	transduction	_	NOUN	_	Number=Sing	_	_	_	_
12	pathway	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	monocyte	_	NOUN	_	VerbForm=Inf	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	pinpoints	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	potential	_	ADJ	_	Degree=Pos	_	_	_	_
22	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
23	whereby	_	ADV	_	_	_	_	_	_
24	HCMV	_	PROPN	_	Number=Sing	_	_	_	_
25	infection	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
28	can	_	AUX	_	VerbForm=Fin	_	_	_	_
29	result	_	VERB	_	VerbForm=Inf	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	profound	_	ADJ	_	Degree=Pos	_	_	_	_
32	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	especially	_	ADV	_	_	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
37	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	type	_	NOUN	_	Number=Sing	_	_	_	_
40	conditions	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012642	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	that	_	SCONJ	_	_	_	_	_	_
3	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	rate	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	limiting	_	VERB	_	VerbForm=Ger	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Cyclosporine	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	CsA	_	NOUN	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
9	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
10	drug	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	probe	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	dissect	_	VERB	_	VerbForm=Inf	_	_	_	_
16	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
17	signaling	_	NOUN	_	Number=Sing	_	_	_	_
18	pathways	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	CsA	_	PROPN	_	Number=Sing	_	_	_	_
5	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	lymphocyte	_	ADJ	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	SCONJ	_	_	_	_	_	_
10	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	CN	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
3	use	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	CsA	_	PROPN	_	Number=Sing	_	_	_	_
6	treatment	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibits	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	50	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	SYM	_	_	_	_	_	_
10	75	_	NUM	_	NumType=Card	_	_	_	_
11	%	_	SYM	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	CN	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	circulating	_	VERB	_	VerbForm=Ger	_	_	_	_
17	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	modeled	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	degree	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CN	_	PROPN	_	Number=Sing	_	_	_	_
7	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	primary	_	ADJ	_	Degree=Pos	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vitro	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	order	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	study	_	VERB	_	VerbForm=Inf	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	effect	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	partial	_	ADJ	_	Degree=Pos	_	_	_	_
22	CN	_	PROPN	_	Number=Sing	_	_	_	_
23	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
27	signaling	_	NOUN	_	Number=Sing	_	_	_	_
28	events	_	NOUN	_	Number=Plur	_	_	_	_
29	that	_	PRON	_	PronType=Rel	_	_	_	_
30	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	CsA	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	calcium	_	NOUN	_	Number=Sing	_	_	_	_
9	ionophore	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	degree	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	reduction	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	CN	_	PROPN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	similar	_	ADJ	_	Degree=Pos	_	_	_	_
23	degree	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	each	_	DET	_	_	_	_	_	_
28	event	_	NOUN	_	Number=Sing	_	_	_	_
29	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	:	_	PUNCT	_	_	_	_	_	_
31	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
34	factor	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	T	_	NOUN	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	proteins	_	NOUN	_	Number=Plur	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
42	DNA	_	NOUN	_	Number=Sing	_	_	_	_
43	binding	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	activation	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
48	transfected	_	VERB	_	Degree=Pos	_	_	_	_
49	reporter	_	NOUN	_	Number=Sing	_	_	_	_
50	gene	_	NOUN	_	Number=Sing	_	_	_	_
51	construct	_	NOUN	_	Number=Sing	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	IFN	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	gamma	_	NOUN	_	Number=Sing	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	IL	_	PROPN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	2	_	NUM	_	NumType=Card	_	_	_	_
60	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
61	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	and	_	CCONJ	_	_	_	_	_	_
64	IFN	_	PROPN	_	Number=Sing	_	_	_	_
65	-	_	PUNCT	_	_	_	_	_	_
66	gamma	_	NOUN	_	Number=Sing	_	_	_	_
67	production	_	NOUN	_	Number=Sing	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	degree	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CN	_	PROPN	_	Number=Sing	_	_	_	_
7	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	reflected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	similar	_	ADJ	_	Degree=Pos	_	_	_	_
13	degree	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	reduction	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
18	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	IFN	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	gamma	_	NOUN	_	Number=Sing	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	allogeneic	_	ADJ	_	Degree=Pos	_	_	_	_
27	mixed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	lymphocyte	_	ADJ	_	Number=Sing	_	_	_	_
29	cultures	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	CN	_	PROPN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	rate	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	limiting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	primary	_	ADJ	_	Degree=Pos	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	reduction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CN	_	PROPN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	CsA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	patients	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	similar	_	ADJ	_	Degree=Pos	_	_	_	_
19	degree	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	reduction	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	lymphocyte	_	ADJ	_	Degree=Pos	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	accounts	_	NOUN	_	Number=Plur	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	immunosuppression	_	NOUN	_	Number=Sing	_	_	_	_
32	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012646	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	E1	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	YY1	_	NOUN	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	newly	_	ADV	_	_	_	_	_	_
16	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	element	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
21	exon	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	DR	_	NOUN	_	Number=Sing	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	unrecognized	_	ADJ	_	Degree=Pos	_	_	_	_
4	element	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	downstream	_	ADV	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	start	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
17	exon	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	DR	_	PROPN	_	Number=Sing	_	_	_	_
21	alpha	_	PROPN	_	Number=Sing	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	defined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	enhances	_	VERB	_	Number=Plur	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	up	_	ADP	_	_	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	eightfold	_	NOUN	_	VerbForm=Inf	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	position	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
39	manner	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	abolished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	extract	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	decreased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	DR	_	PROPN	_	Number=Sing	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	basal	_	ADJ	_	Degree=Pos	_	_	_	_
32	level	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Significant	_	ADJ	_	Degree=Pos	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	homology	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	element	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	DNA	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	DR	_	PROPN	_	Number=Sing	_	_	_	_
15	beta	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	DP	_	PROPN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	beta	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	DQ	_	NOUN	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	always	_	ADV	_	_	_	_	_	_
29	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	downstream	_	ADV	_	_	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
34	start	_	NOUN	_	Number=Sing	_	_	_	_
35	site	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	DR	_	PROPN	_	Number=Sing	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	DP	_	PROPN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	element	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	DQ	_	NOUN	_	Number=Sing	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	E1	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	YY1	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	previously	_	ADV	_	_	_	_	_	_
5	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	Ig	_	PROPN	_	Number=Sing	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	3	_	NUM	_	NumType=Card	_	_	_	_
14	'	_	PUNCT	_	_	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	Ig	_	PROPN	_	Number=Sing	_	_	_	_
19	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
20	chain	_	NOUN	_	Number=Sing	_	_	_	_
21	mu	_	NOUN	_	Number=Sing	_	_	_	_
22	E1	_	NOUN	_	Number=Sing	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	thus	_	ADV	_	_	_	_	_	_
26	also	_	ADV	_	_	_	_	_	_
27	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	be	_	AUX	_	VerbForm=Inf	_	_	_	_
30	quite	_	ADV	_	_	_	_	_	_
31	important	_	ADJ	_	Degree=Pos	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	regulation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	MHC	_	PROPN	_	Number=Sing	_	_	_	_
37	class	_	NOUN	_	Number=Sing	_	_	_	_
38	II	_	NUM	_	NumType=Card	_	_	_	_
39	gene	_	NOUN	_	Number=Sing	_	_	_	_
40	expression	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012648	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	elements	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	repress	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	adult	_	NOUN	_	Number=Sing	_	_	_	_
11	beta	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	like	_	ADP	_	Degree=Pos	_	_	_	_
14	globin	_	ADJ	_	Degree=Pos	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	primitive	_	ADJ	_	Degree=Pos	_	_	_	_
19	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
20	environment	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	investigations	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	focused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	on	_	SCONJ	_	_	_	_	_	_
6	localizing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	cis	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	elements	_	NOUN	_	Number=Plur	_	_	_	_
10	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	down	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	adult	_	NOUN	_	Number=Sing	_	_	_	_
18	beta	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	like	_	ADP	_	Degree=Pos	_	_	_	_
21	globin	_	ADJ	_	Degree=Pos	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	delta	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	beta	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	immature	_	NOUN	_	Degree=Pos	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	primitive	_	ADJ	_	Degree=Pos	_	_	_	_
33	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
34	tissues	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	after	_	ADP	_	_	_	_	_	_
6	transfection	_	NOUN	_	Number=Sing	_	_	_	_
7	into	_	ADP	_	_	_	_	_	_
8	K562	_	NUM	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	erythroleukemia	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	line	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	fetal	_	ADJ	_	Number=Sing	_	_	_	_
20	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	sequences	_	NOUN	_	Number=Plur	_	_	_	_
4	included	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	delta	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	beta	_	NOUN	_	Number=Sing	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	'	_	PUNCT	_	_	_	_	_	_
10	flanking	_	VERB	_	VerbForm=Ger	_	_	_	_
11	regions	_	NOUN	_	Number=Plur	_	_	_	_
12	extending	_	VERB	_	VerbForm=Ger	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	approximately	_	ADV	_	_	_	_	_	_
15	-	_	SYM	_	_	_	_	_	_
16	500	_	NUM	_	NumType=Card	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	+	_	SYM	_	_	_	_	_	_
19	50	_	NUM	_	NumType=Card	_	_	_	_
20	bp	_	PROPN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	regions	_	NOUN	_	Number=Plur	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	delta	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	beta	_	NOUN	_	Number=Sing	_	_	_	_
30	5	_	NUM	_	NumType=Card	_	_	_	_
31	'	_	PUNCT	_	_	_	_	_	_
32	flanking	_	VERB	_	VerbForm=Ger	_	_	_	_
33	regions	_	NOUN	_	Number=Plur	_	_	_	_
34	extending	_	VERB	_	VerbForm=Ger	_	_	_	_
35	from	_	ADP	_	_	_	_	_	_
36	approximately	_	ADV	_	_	_	_	_	_
37	-	_	SYM	_	_	_	_	_	_
38	250	_	NUM	_	NumType=Card	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	+	_	SYM	_	_	_	_	_	_
41	50	_	NUM	_	NumType=Card	_	_	_	_
42	bp	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	chimeric	_	ADJ	_	Degree=Pos	_	_	_	_
46	promoter	_	NOUN	_	Number=Sing	_	_	_	_
47	constructions	_	NOUN	_	Number=Plur	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	which	_	PRON	_	PronType=Rel	_	_	_	_
50	consisted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
53	distal	_	ADJ	_	Degree=Pos	_	_	_	_
54	delta	_	NOUN	_	Number=Sing	_	_	_	_
55	or	_	CCONJ	_	_	_	_	_	_
56	beta	_	NOUN	_	Number=Sing	_	_	_	_
57	fragment	_	NOUN	_	Number=Sing	_	_	_	_
58	fused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
59	to	_	ADP	_	_	_	_	_	_
60	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
61	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
62	beta	_	NOUN	_	Number=Sing	_	_	_	_
63	or	_	CCONJ	_	_	_	_	_	_
64	delta	_	NOUN	_	Number=Sing	_	_	_	_
65	sequence	_	NOUN	_	Number=Sing	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	CAT	_	NOUN	_	Number=Sing	_	_	_	_
3	reporter	_	NOUN	_	Number=Sing	_	_	_	_
4	constructions	_	NOUN	_	Number=Plur	_	_	_	_
5	no	_	DET	_	_	_	_	_	_
6	appreciable	_	ADJ	_	Degree=Pos	_	_	_	_
7	level	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	CAT	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	supported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	beta	_	NOUN	_	Number=Sing	_	_	_	_
16	globin	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	only	_	ADV	_	_	_	_	_	_
21	low	_	ADJ	_	Degree=Pos	_	_	_	_
22	level	_	NOUN	_	Number=Sing	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	delta	_	PROPN	_	Number=Sing	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Truncation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	beta	_	NOUN	_	Number=Sing	_	_	_	_
5	globin	_	NOUN	_	Number=Sing	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	3	_	NUM	_	NumType=Card	_	_	_	_
13	fold	_	NOUN	_	Number=Sing	_	_	_	_
14	increase	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	deletion	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
8	portion	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	delta	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	10	_	NUM	_	NumType=Card	_	_	_	_
17	fold	_	NOUN	_	Number=Sing	_	_	_	_
18	decrease	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Coupling	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	upstream	_	ADJ	_	Number=Sing	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	globin	_	NOUN	_	Number=Sing	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	approximately	_	ADV	_	_	_	_	_	_
10	-	_	SYM	_	_	_	_	_	_
11	500	_	NUM	_	NumType=Card	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	250	_	NUM	_	NumType=Card	_	_	_	_
15	bp	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	delta	_	NOUN	_	Number=Sing	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	fragment	_	NOUN	_	Number=Sing	_	_	_	_
22	led	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	complete	_	ADJ	_	Degree=Pos	_	_	_	_
25	extinction	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	negative	_	ADJ	_	Degree=Pos	_	_	_	_
34	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
35	effect	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	beta	_	NOUN	_	Number=Sing	_	_	_	_
39	globin	_	NOUN	_	Degree=Pos	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
42	element	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	s	_	X	_	_	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Fusion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
5	portion	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	delta	_	PROPN	_	Number=Sing	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	beta	_	NOUN	_	Number=Sing	_	_	_	_
14	globin	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	yielded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	modest	_	ADJ	_	Degree=Pos	_	_	_	_
19	increase	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	strength	_	NOUN	_	Number=Sing	_	_	_	_
23	relative	_	ADV	_	_	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	beta	_	NOUN	_	Number=Sing	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	presence	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	positive	_	ADJ	_	Degree=Pos	_	_	_	_
37	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
38	element	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	s	_	X	_	_	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	upstream	_	ADJ	_	Number=Sing	_	_	_	_
45	delta	_	PROPN	_	Number=Sing	_	_	_	_
46	globin	_	PROPN	_	Number=Sing	_	_	_	_
47	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
48	region	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Site	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	repressor	_	NOUN	_	Number=Sing	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	BP1	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	BP2	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
18	portion	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	beta	_	NOUN	_	Number=Sing	_	_	_	_
22	globin	_	NOUN	_	Degree=Pos	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	flanking	_	VERB	_	Number=Sing	_	_	_	_
25	region	_	NOUN	_	Number=Sing	_	_	_	_
26	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	4	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	SYM	_	_	_	_	_	_
31	6	_	NUM	_	NumType=Card	_	_	_	_
32	fold	_	NOUN	_	Number=Sing	_	_	_	_
33	increase	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	promoter	_	NOUN	_	Number=Sing	_	_	_	_
36	activity	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	DNase	_	NOUN	_	Number=Sing	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	footprinting	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	upstream	_	ADJ	_	Number=Sing	_	_	_	_
7	delta	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	globin	_	PROPN	_	Number=Sing	_	_	_	_
10	region	_	NOUN	_	Number=Sing	_	_	_	_
11	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	protected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	sequences	_	NOUN	_	Number=Plur	_	_	_	_
14	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	consensus	_	NOUN	_	Number=Sing	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	GATA	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	BP2	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	confirm	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	sequences	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	region	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	adult	_	NOUN	_	Number=Sing	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	globin	_	ADJ	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
23	suppression	_	NOUN	_	Number=Sing	_	_	_	_
24	early	_	ADV	_	Degree=Pos	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	development	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	then	_	ADV	_	PronType=Dem	_	_	_	_
29	may	_	AUX	_	VerbForm=Fin	_	_	_	_
30	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
31	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	at	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	later	_	ADJ	_	Degree=Cmp	_	_	_	_
36	stage	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012649	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	7	_	NUM	_	NumType=Card	_	_	_	_
8	induce	_	NOUN	_	Number=Sing	_	_	_	_
9	heterodimerization	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
12	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
16	blood	_	NOUN	_	Number=Sing	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	lymphoblasts	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Despite	_	ADP	_	_	_	_	_	_
2	differences	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	responses	_	NOUN	_	Number=Plur	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	7	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
22	modulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	T	_	NOUN	_	NumType=Card	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	functions	_	NOUN	_	Number=Plur	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	signal	_	NOUN	_	Number=Sing	_	_	_	_
30	transducers	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	activators	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	STAT	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	proteins	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	contribution	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	isoforms	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	STAT5	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	STAT5A	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	STAT5B	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	7	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
31	blood	_	NOUN	_	Number=Sing	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	lymphoblasts	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	assembly	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	STAT5A	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	STAT5B	_	NOUN	_	Number=Sing	_	_	_	_
9	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	complexes	_	NOUN	_	Number=Plur	_	_	_	_
11	capable	_	ADJ	_	Degree=Pos	_	_	_	_
12	of	_	SCONJ	_	_	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	interferon	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	gamma	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	sequence	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	GAS	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
27	complexes	_	NOUN	_	Number=Plur	_	_	_	_
28	rapidly	_	ADV	_	_	_	_	_	_
29	translocated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	within	_	ADP	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	min	_	NOUN	_	Number=Plur	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	into	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	or	_	CCONJ	_	_	_	_	_	_
44	IL	_	PROPN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	7	_	NUM	_	NumType=Card	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	cells	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	translocation	_	NOUN	_	Number=Sing	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	delayed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	7	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	as	_	SCONJ	_	_	_	_	_	_
15	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	7	_	NUM	_	NumType=Card	_	_	_	_
8	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	equivalent	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	ability	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
15	tyrosine	_	ADJ	_	Degree=Pos	_	_	_	_
16	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	STAT5A	_	PROPN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	STAT5B	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	facilitate	_	VERB	_	VerbForm=Inf	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
27	STATs	_	NOUN	_	Number=Plur	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	immobilized	_	VERB	_	Degree=Pos	_	_	_	_
31	GAS	_	NOUN	_	Number=Sing	_	_	_	_
32	element	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	7	_	NUM	_	NumType=Card	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
11	amounts	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	STAT5A	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	STAT5B	_	NOUN	_	Number=Sing	_	_	_	_
16	heterodimerization	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
6	association	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	STAT3	_	PROPN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	each	_	DET	_	_	_	_	_	_
11	STAT5	_	NOUN	_	Number=Sing	_	_	_	_
12	isomer	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	7	_	NUM	_	NumType=Card	_	_	_	_
12	induce	_	NOUN	_	Number=Sing	_	_	_	_
13	assembly	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	STAT	_	PROPN	_	Number=Sing	_	_	_	_
16	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	similar	_	ADJ	_	Degree=Pos	_	_	_	_
20	manner	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	that	_	DET	_	_	_	_	_	_
23	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
24	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
25	responses	_	NOUN	_	Number=Plur	_	_	_	_
26	may	_	AUX	_	VerbForm=Fin	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	driven	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	induction	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	similar	_	ADJ	_	Degree=Pos	_	_	_	_
33	sets	_	NOUN	_	Number=Plur	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	genes	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012651	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
17	line	_	NOUN	_	Number=Sing	_	_	_	_
18	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	under	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	control	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
21	proteins	_	NOUN	_	Number=Plur	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	viral	_	ADJ	_	Degree=Pos	_	_	_	_
27	long	_	ADJ	_	Degree=Pos	_	_	_	_
28	terminal	_	NOUN	_	Number=Sing	_	_	_	_
29	repeat	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	LTR	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Among	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	binding	_	VERB	_	Number=Sing	_	_	_	_
6	regions	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	HIV	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	LTR	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
18	region	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	at	_	ADV	_	_	_	_	_	_
5	least	_	ADV	_	Degree=Sup	_	_	_	_
6	one	_	NUM	_	NumType=Card	_	_	_	_
7	inducible	_	ADJ	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	C1	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	one	_	NUM	_	NumType=Card	_	_	_	_
13	constitutive	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	C2	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	can	_	AUX	_	VerbForm=Fin	_	_	_	_
19	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
7	surface	_	NOUN	_	Number=Sing	_	_	_	_
8	charge	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	since	_	SCONJ	_	_	_	_	_	_
11	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	separable	_	ADJ	_	Degree=Pos	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	anion	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	exchange	_	NOUN	_	Number=Sing	_	_	_	_
18	chromatography	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Bivalent	_	ADJ	_	Degree=Pos	_	_	_	_
2	cations	_	NOUN	_	Number=Plur	_	_	_	_
3	such	_	ADJ	_	Degree=Pos	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	Mg2	_	NOUN	_	Number=Sing	_	_	_	_
6	+	_	SYM	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Zn2	_	NOUN	_	Number=Sing	_	_	_	_
9	+	_	CCONJ	_	_	_	_	_	_
10	differentially	_	ADV	_	_	_	_	_	_
11	affect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	domain	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	C1	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	C2	_	PROPN	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	similar	_	ADJ	_	Degree=Pos	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	subunit	_	NOUN	_	Number=Sing	_	_	_	_
23	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
3	C1	_	PROPN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	partially	_	ADV	_	_	_	_	_	_
7	purified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	three	_	NUM	_	NumType=Card	_	_	_	_
10	chromatographic	_	ADJ	_	Degree=Pos	_	_	_	_
11	steps	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	u.v.	_	PROPN	_	Number=Sing	_	_	_	_
16	cross	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	47	_	NUM	_	NumType=Card	_	_	_	_
22	kDa	_	NOUN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012652	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cyclosporin	_	VERB	_	Number=Sing	_	_	_	_
2	A	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
5	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
16	acid	_	ADJ	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
19	serine	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	threonine	_	ADJ	_	Number=Sing	_	_	_	_
22	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	through	_	ADP	_	_	_	_	_	_
14	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	TCR	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	accessory	_	ADJ	_	Degree=Pos	_	_	_	_
22	receptors	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	recently	_	ADV	_	_	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
7	acid	_	ADJ	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
10	Ser	_	NOUN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	Thr	_	NOUN	_	Number=Sing	_	_	_	_
13	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	involved	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
19	A	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	insensitive	_	ADJ	_	Degree=Pos	_	_	_	_
22	pathway	_	NOUN	_	Number=Sing	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	selectively	_	ADV	_	_	_	_	_	_
25	transmits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
27	signals	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	whether	_	SCONJ	_	_	_	_	_	_
8	activities	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	both	_	DET	_	_	_	_	_	_
3	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
5	blood	_	NOUN	_	Number=Sing	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	tumorigenic	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	lines	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	at	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	level	_	NOUN	_	Number=Sing	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
28	acid	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	active	_	ADJ	_	Degree=Pos	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	differentially	_	ADV	_	_	_	_	_	_
13	influenced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	:	_	PUNCT	_	_	_	_	_	_
15	upon	_	ADP	_	_	_	_	_	_
16	down	_	ADP	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	modulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
21	acid	_	ADJ	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
24	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	octamer	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	PROPN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	NF	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	T	_	PROPN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	proteins	_	NOUN	_	Number=Plur	_	_	_	_
42	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
43	abrogated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	while	_	SCONJ	_	_	_	_	_	_
46	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
47	by	_	ADP	_	_	_	_	_	_
48	AP	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	1	_	NUM	_	NumType=Card	_	_	_	_
51	proteins	_	NOUN	_	Number=Plur	_	_	_	_
52	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
53	even	_	ADV	_	_	_	_	_	_
54	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012653	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	TCL1	_	NOUN	_	Number=Sing	_	_	_	_
2	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	preleukemic	_	ADJ	_	Degree=Pos	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	case	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	ataxia	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	telangiectasia	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	TCL1	_	NOUN	_	Number=Sing	_	_	_	_
3	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
7	14q32.1	_	NUM	_	NumType=Card	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	involved	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
12	translocations	_	NOUN	_	Number=Plur	_	_	_	_
13	[	_	PUNCT	_	_	_	_	_	_
14	t	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	14	_	NUM	_	NumType=Card	_	_	_	_
17	;	_	PUNCT	_	_	_	_	_	_
18	14	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	q11	_	NUM	_	NumType=Card	_	_	_	_
22	;	_	PUNCT	_	_	_	_	_	_
23	q32.1	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	t(7;14	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	q35;q32.1	_	NUM	_	NumType=Card	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	]	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	inversions	_	NOUN	_	Number=Plur	_	_	_	_
34	[	_	PUNCT	_	_	_	_	_	_
35	inv14	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	q11;q32.1	_	NUM	_	NumType=Card	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	]	_	PUNCT	_	_	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	TCR	_	NOUN	_	Number=Sing	_	_	_	_
42	alpha	_	NOUN	_	Number=Sing	_	_	_	_
43	/	_	PUNCT	_	_	_	_	_	_
44	beta	_	NOUN	_	Number=Sing	_	_	_	_
45	loci	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
48	leukemias	_	NOUN	_	Number=Plur	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	such	_	ADJ	_	Degree=Pos	_	_	_	_
51	as	_	ADP	_	_	_	_	_	_
52	T-prolymphocytic	_	ADJ	_	Number=Sing	_	_	_	_
53	(	_	PUNCT	_	_	_	_	_	_
54	T	_	NOUN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	PLL	_	NOUN	_	Number=Sing	_	_	_	_
57	)	_	PUNCT	_	_	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	involved	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	T-	_	PUNCT	_	_	_	_	_	_
7	acute	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
11	leukemias	_	NOUN	_	Number=Plur	_	_	_	_
12	arising	_	VERB	_	VerbForm=Ger	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	cases	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	ataxia	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	telangiectasia	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	AT	_	ADP	_	_	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
25	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
3	rearrangements	_	NOUN	_	Number=Plur	_	_	_	_
4	occur	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	clonally	_	ADV	_	_	_	_	_	_
9	expanded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	AT	_	ADP	_	_	_	_	_	_
14	patients	_	NOUN	_	Number=Sing	_	_	_	_
15	before	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	appearance	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	overt	_	ADJ	_	Degree=Pos	_	_	_	_
21	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	TCL1	_	NOUN	_	Number=Sing	_	_	_	_
8	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	protein	_	VERB	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
13	blood	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	PBLs	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	four	_	NUM	_	NumType=Card	_	_	_	_
20	AT	_	ADP	_	_	_	_	_	_
21	cases	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
25	controls	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	TCL1	_	PROPN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	overexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	PBLs	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	AT	_	ADP	_	_	_	_	_	_
15	patient	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	large	_	ADJ	_	Degree=Pos	_	_	_	_
19	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
20	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
21	population	_	NOUN	_	Number=Sing	_	_	_	_
22	exhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	t	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	14	_	NUM	_	NumType=Card	_	_	_	_
27	;	_	PUNCT	_	_	_	_	_	_
28	14	_	NUM	_	NumType=Card	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	translocation	_	NOUN	_	Number=Sing	_	_	_	_
31	but	_	CCONJ	_	_	_	_	_	_
32	not	_	PART	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	other	_	ADJ	_	Degree=Pos	_	_	_	_
39	cases	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Fluorescence	_	NOUN	_	Number=Sing	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	situ	_	NOUN	_	Number=Sing	_	_	_	_
4	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	TCL1	_	PROPN	_	Number=Sing	_	_	_	_
8	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
9	locus	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	lymphocyte	_	VERB	_	Number=Sing	_	_	_	_
12	metaphases	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	AT	_	ADP	_	Number=Sing	_	_	_	_
16	patient	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
20	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
21	expansion	_	NOUN	_	Number=Sing	_	_	_	_
22	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	that	_	SCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	breakpoint	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	t	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	14	_	NUM	_	NumType=Card	_	_	_	_
31	;	_	PUNCT	_	_	_	_	_	_
32	14	_	NUM	_	NumType=Card	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	translocation	_	NOUN	_	Number=Sing	_	_	_	_
35	lies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	within	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	TCL1	_	PROPN	_	Number=Sing	_	_	_	_
39	locus	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	by	_	ADP	_	_	_	_	_	_
44	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
45	inverted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	duplication	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	distal	_	ADJ	_	Degree=Pos	_	_	_	_
50	part	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
53	14	_	NUM	_	NumType=Card	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TCL1	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	preleukemic	_	ADJ	_	Degree=Pos	_	_	_	_
10	clonal	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	consequence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	chromosome	_	NOUN	_	Degree=Pos	_	_	_	_
17	translocation	_	NOUN	_	Number=Sing	_	_	_	_
18	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
19	sequences	_	NOUN	_	Number=Plur	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	TCR	_	NOUN	_	Number=Sing	_	_	_	_
23	locus	_	NOUN	_	Number=Sing	_	_	_	_
24	at	_	ADP	_	_	_	_	_	_
25	14q11	_	NUM	_	NumType=Card	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Deregulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TCL1	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	event	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	initiation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	malignancy	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	types	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	leukemias	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	represents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	potential	_	ADJ	_	Degree=Pos	_	_	_	_
22	tool	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
25	evaluation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012656	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Arrested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	development	_	NOUN	_	Number=Sing	_	_	_	_
3	:	_	PUNCT	_	_	_	_	_	_
4	understanding	_	NOUN	_	Number=Sing	_	_	_	_
5	v-abl	_	NOUN	_	Number=Sing	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
4	kinase	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	v-abl	_	NOUN	_	Number=Sing	_	_	_	_
9	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
10	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
12	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	subvert	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	normal	_	ADJ	_	Degree=Pos	_	_	_	_
17	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
18	messenger	_	NOUN	_	Number=Sing	_	_	_	_
19	systems	_	NOUN	_	Number=Plur	_	_	_	_
20	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	growth	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Transformation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	bone	_	NOUN	_	Number=Sing	_	_	_	_
4	marrow	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Abelson	_	PROPN	_	Number=Sing	_	_	_	_
8	murine	_	NOUN	_	Number=Sing	_	_	_	_
9	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	results	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	appearance	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	B	_	ADJ	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lineage	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	arrested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	pre	_	NUM	_	_	_	_	_	_
24	-B	_	NOUN	_	Number=Sing	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	stage	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	reports	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
8	high	_	ADJ	_	Degree=Pos	_	_	_	_
9	v-abl	_	ADJ	_	Degree=Pos	_	_	_	_
10	kinase	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	DNA	_	NOUN	_	Number=Sing	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	low	_	ADJ	_	Degree=Pos	_	_	_	_
24	level	_	NOUN	_	Number=Sing	_	_	_	_
25	RAG	_	NOUN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	v-abl	_	NOUN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	inhibiting	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	B	_	ADJ	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	SCONJ	_	_	_	_	_	_
15	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
16	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
17	two	_	NUM	_	NumType=Card	_	_	_	_
18	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
19	elements	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	maturation	_	NOUN	_	Number=Sing	_	_	_	_
23	pathway	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012657	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	family	_	NOUN	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	NFAT1	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	NFATc	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	NFAT3	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	NFAT4	_	NOUN	_	Number=Sing	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	NFATx	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	NFATc3	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	play	_	VERB	_	VerbForm=Inf	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	key	_	ADJ	_	Degree=Pos	_	_	_	_
29	role	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
35	genes	_	NOUN	_	Number=Plur	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	other	_	ADJ	_	Degree=Pos	_	_	_	_
38	genes	_	NOUN	_	Number=Plur	_	_	_	_
39	during	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	immune	_	ADJ	_	Degree=Pos	_	_	_	_
42	response	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	defined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	NFAT1	_	PROPN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	NFAT1	_	PROPN	_	Number=Sing	_	_	_	_
2	possesses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	two	_	NUM	_	NumType=Card	_	_	_	_
4	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
5	domains	_	NOUN	_	Number=Plur	_	_	_	_
6	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
7	sequences	_	NOUN	_	Number=Plur	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	conserved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	other	_	ADJ	_	Degree=Pos	_	_	_	_
14	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	family	_	NOUN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	conserved	_	VERB	_	Degree=Pos	_	_	_	_
22	DNA	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	binding	_	VERB	_	Number=Sing	_	_	_	_
25	domain	_	NOUN	_	Number=Sing	_	_	_	_
26	that	_	PRON	_	PronType=Rel	_	_	_	_
27	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	SCONJ	_	_	_	_	_	_
31	cooperating	_	VERB	_	VerbForm=Ger	_	_	_	_
32	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	factors	_	NOUN	_	Number=Plur	_	_	_	_
35	even	_	ADV	_	_	_	_	_	_
36	when	_	ADV	_	PronType=Int	_	_	_	_
37	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	absence	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	other	_	ADJ	_	Degree=Pos	_	_	_	_
45	regions	_	NOUN	_	Number=Plur	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	protein	_	NOUN	_	Number=Sing	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	NH2	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	terminal	_	NOUN	_	Number=Sing	_	_	_	_
8	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
9	domain	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	that	_	PRON	_	PronType=Rel	_	_	_	_
18	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	several	_	ADJ	_	Degree=Pos	_	_	_	_
20	conserved	_	VERB	_	Degree=Pos	_	_	_	_
21	sequence	_	NOUN	_	Number=Sing	_	_	_	_
22	motifs	_	NOUN	_	Number=Plur	_	_	_	_
23	represented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	only	_	ADV	_	_	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
28	family	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	emphasize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	at	_	ADP	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	predict	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	significant	_	ADJ	_	Degree=Pos	_	_	_	_
19	differences	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	architecture	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	cooperative	_	ADJ	_	Degree=Pos	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	complexes	_	NOUN	_	Number=Plur	_	_	_	_
27	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
28	different	_	ADJ	_	Degree=Pos	_	_	_	_
29	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	family	_	NOUN	_	Number=Sing	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012661	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	cultures	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	cyclic	_	ADJ	_	Number=Sing	_	_	_	_
17	AMP	_	NOUN	_	Number=Sing	_	_	_	_
18	signaling	_	NOUN	_	Number=Sing	_	_	_	_
19	pathway	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	cascade	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
14	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
17	into	_	ADP	_	_	_	_	_	_
18	effector	_	NOUN	_	Number=Sing	_	_	_	_
19	phenotypes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	belonging	_	VERB	_	VerbForm=Ger	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	signal	_	NOUN	_	Number=Sing	_	_	_	_
10	transducer	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	activator	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	STAT	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	family	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	PHA	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	T	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	cross	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	linking	_	NOUN	_	VerbForm=Ger	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	surface	_	NOUN	_	Number=Sing	_	_	_	_
39	CD3	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	STAT	_	NOUN	_	Number=Sing	_	_	_	_
10	DNA	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	sustained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	several	_	ADJ	_	Degree=Pos	_	_	_	_
20	days	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	predominantly	_	ADV	_	_	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
32	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	actinomycin	_	NOUN	_	Number=Sing	_	_	_	_
37	D.	_	PROPN	_	Number=Sing	_	_	_	_
38	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	Stat3	_	PROPN	_	Number=Sing	_	_	_	_
42	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	protein	_	NOUN	_	Number=Sing	_	_	_	_
45	levels	_	NOUN	_	Number=Plur	_	_	_	_
46	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
47	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	respectively	_	ADV	_	_	_	_	_	_
50	4	_	NUM	_	NumType=Card	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	24	_	NUM	_	NumType=Card	_	_	_	_
53	h	_	NOUN	_	Number=Plur	_	_	_	_
54	after	_	ADP	_	_	_	_	_	_
55	activation	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
5	signal	_	NOUN	_	Number=Sing	_	_	_	_
6	transduction	_	NOUN	_	Number=Sing	_	_	_	_
7	pathway	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	skews	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	toward	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	Th2	_	ADJ	_	Degree=Pos	_	_	_	_
16	pattern	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	preferential	_	ADJ	_	Degree=Pos	_	_	_	_
22	suppression	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
2	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	components	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	4	_	NUM	_	NumType=Card	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	chain	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	CD69	_	PROPN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	induction	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	activator	_	NOUN	_	Number=Sing	_	_	_	_
33	protein	_	NOUN	_	Number=Sing	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	factors	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
2	signaling	_	VERB	_	Number=Sing	_	_	_	_
3	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
5	at	_	ADP	_	_	_	_	_	_
6	several	_	ADJ	_	Degree=Pos	_	_	_	_
7	different	_	ADJ	_	Degree=Pos	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	including	_	VERB	_	VerbForm=Ger	_	_	_	_
11	suppression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	DNA	_	NOUN	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	down	_	ADP	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	regulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Stat1	_	PROPN	_	Number=Sing	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
24	levels	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	STAT	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
12	pathway	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	functional	_	ADJ	_	Degree=Pos	_	_	_	_
19	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	activated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
28	Janus	_	PROPN	_	Number=Sing	_	_	_	_
29	kinase	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	STAT	_	PROPN	_	Number=Sing	_	_	_	_
32	signaling	_	NOUN	_	Number=Sing	_	_	_	_
33	pathway	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012663	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Neutrophil	_	PROPN	_	Number=Sing	_	_	_	_
2	maturation	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	retinoic	_	ADJ	_	Number=Sing	_	_	_	_
8	acid	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Neutrophil	_	PROPN	_	Number=Sing	_	_	_	_
2	maturation	_	NOUN	_	Number=Sing	_	_	_	_
3	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	well	_	ADV	_	Degree=Pos	_	_	_	_
6	defined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	morphological	_	ADJ	_	Degree=Pos	_	_	_	_
8	stages	_	NOUN	_	Number=Plur	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	correlate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	acquisition	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
16	markers	_	NOUN	_	Number=Plur	_	_	_	_
17	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
20	function	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	variety	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	play	_	VERB	_	VerbForm=Inf	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
13	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
14	maturation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	including	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
19	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	derivative	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
23	acid	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
2	acid	_	NOUN	_	Number=Sing	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	directly	_	ADV	_	_	_	_	_	_
5	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	via	_	ADP	_	_	_	_	_	_
9	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	receptors	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	can	_	AUX	_	VerbForm=Fin	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	turn	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	activate	_	ADJ	_	VerbForm=Inf	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	target	_	NOUN	_	Number=Sing	_	_	_	_
25	genes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
5	acid	_	NOUN	_	Number=Sing	_	_	_	_
6	during	_	ADP	_	_	_	_	_	_
7	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
8	maturation	_	NOUN	_	Number=Sing	_	_	_	_
9	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	variety	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	sources	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	present	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	review	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
11	acid	_	ADJ	_	Number=Sing	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	action	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	major	_	ADJ	_	Degree=Pos	_	_	_	_
17	evidence	_	NOUN	_	Number=Sing	_	_	_	_
18	showing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	normal	_	ADJ	_	Degree=Pos	_	_	_	_
21	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
22	signaling	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	neutrophil	_	NOUN	_	Degree=Pos	_	_	_	_
27	maturation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012665	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	Ca2	_	PROPN	_	Number=Sing	_	_	_	_
14	+/	_	SYM	_	_	_	_	_	_
15	calmodulin	_	NOUN	_	Number=Sing	_	_	_	_
16	kinase	_	NOUN	_	Number=Sing	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	IV	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	Gr.	_	PROPN	_	Number=Sing	_	_	_	_
21	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	Ca2+/calmodulin-dependent	_	PROPN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	kinase	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	CaMK	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	type	_	NOUN	_	Number=Sing	_	_	_	_
29	IV	_	NOUN	_	Number=Sing	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	Gr	_	NOUN	_	Number=Sing	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	selectively	_	ADV	_	_	_	_	_	_
34	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	T	_	PROPN	_	Number=Sing	_	_	_	_
37	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	after	_	SCONJ	_	_	_	_	_	_
42	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
43	via	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	T	_	PROPN	_	Number=Sing	_	_	_	_
46	cell	_	NOUN	_	Number=Sing	_	_	_	_
47	antigen	_	NOUN	_	Number=Sing	_	_	_	_
48	receptor	_	NOUN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	TCR	_	NOUN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
54	that	_	SCONJ	_	_	_	_	_	_
55	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
56	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
57	some	_	DET	_	_	_	_	_	_
58	of	_	ADP	_	_	_	_	_	_
59	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
60	Ca	_	NOUN	_	Number=Sing	_	_	_	_
61	(	_	PUNCT	_	_	_	_	_	_
62	2	_	NUM	_	NumType=Card	_	_	_	_
63	+)-	_	SYM	_	_	_	_	_	_
64	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
65	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
66	events	_	NOUN	_	Number=Plur	_	_	_	_
67	that	_	PRON	_	PronType=Rel	_	_	_	_
68	follow	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
69	TCR	_	NOUN	_	Number=Sing	_	_	_	_
70	engagement	_	NOUN	_	Number=Sing	_	_	_	_
71	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CaMKIV	_	PROPN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	Gr	_	PROPN	_	Number=Sing	_	_	_	_
8	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	AP	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	alone	_	ADJ	_	_	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	synergy	_	NOUN	_	Number=Sing	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	T	_	PROPN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	p21ras	_	NOUN	_	Number=Plur	_	_	_	_
32	oncoprotein	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	CaMKIV	_	PROPN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_

1	Gr	_	PROPN	_	Number=Sing	_	_	_	_
2	signaling	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	c	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	fos	_	NOUN	_	Number=Sing	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	independent	_	ADJ	_	Degree=Pos	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	p21ras	_	NOUN	_	Number=Sing	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	AP	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	integral	_	ADJ	_	Degree=Pos	_	_	_	_
7	component	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	complex	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	for	_	ADP	_	_	_	_	_	_
26	interleukin	_	NOUN	_	Degree=Pos	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	T	_	PROPN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	CaMKIV	_	PROPN	_	Number=Sing	_	_	_	_
5	/	_	PUNCT	_	_	_	_	_	_
6	Gr	_	NOUN	_	Number=Sing	_	_	_	_
7	reconstitutes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	capacity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
13	component	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	direct	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
21	sites	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	non-T	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	central	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	CaMKIV	_	PROPN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	Gr	_	PROPN	_	Number=Sing	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	Ca	_	PROPN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	+)-	_	SYM	_	_	_	_	_	_
17	regulated	_	VERB	_	Degree=Pos	_	_	_	_
18	activator	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	T	_	PROPN	_	Number=Sing	_	_	_	_
24	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012670	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transactivation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
11	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
12	virus	_	NOUN	_	Number=Sing	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	type	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	II	_	NUM	_	NumType=Card	_	_	_	_
18	Tax	_	NOUN	_	Number=Sing	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
15	lines	_	NOUN	_	Number=Plur	_	_	_	_
16	constitutively	_	ADV	_	_	_	_	_	_
17	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
18	high	_	ADJ	_	Degree=Pos	_	_	_	_
19	levels	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	lines	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
24	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
26	regions	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	involved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	activation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
42	gene	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	constructs	_	NOUN	_	Number=Plur	_	_	_	_
6	drive	_	VERB	_	VerbForm=Inf	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	chloramphenicol	_	PROPN	_	Number=Sing	_	_	_	_
11	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	CAT	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	reporter	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	I-positive	_	ADJ	_	Degree=Pos	_	_	_	_
21	MT	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	which	_	PRON	_	PronType=Rel	_	_	_	_
27	constitutively	_	ADV	_	_	_	_	_	_
28	produce	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	Tax	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	II	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	specifically	_	ADV	_	_	_	_	_	_
19	activated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	uninfected	_	ADJ	_	Degree=Pos	_	_	_	_
30	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	line	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
3	Tax	_	NOUN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	deficient	_	ADJ	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	genes	_	NOUN	_	Number=Plur	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	pathway	_	NOUN	_	Number=Sing	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	unable	_	ADJ	_	Degree=Pos	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
24	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
30	promoter	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	CAT	_	NOUN	_	Number=Sing	_	_	_	_
33	constructs	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	but	_	CCONJ	_	_	_	_	_	_
36	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
37	rescued	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
40	provision	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	p65/p50	_	NUM	_	NumType=Card	_	_	_	_
43	NF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	two	_	NUM	_	NumType=Card	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	like	_	ADJ	_	Degree=Pos	_	_	_	_
11	sites	_	NOUN	_	Number=Plur	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	positions	_	NOUN	_	Number=Plur	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1,065	_	NUM	_	NumType=Card	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	1,056	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	+	_	SYM	_	_	_	_	_	_
21	646	_	NUM	_	NumType=Card	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	+	_	SYM	_	_	_	_	_	_
24	655	_	NUM	_	NumType=Card	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	specifically	_	ADV	_	_	_	_	_	_
27	formed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	complex	_	NOUN	_	Number=Sing	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
36	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
37	extract	_	NOUN	_	Number=Sing	_	_	_	_
38	from	_	ADP	_	_	_	_	_	_
39	MT	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	that	_	SCONJ	_	_	_	_	_	_
45	NF	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
48	bound	_	NOUN	_	Degree=Pos	_	_	_	_
49	with	_	ADP	_	_	_	_	_	_
50	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
51	affinity	_	NOUN	_	Number=Sing	_	_	_	_
52	to	_	ADP	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	3	_	NUM	_	NumType=Card	_	_	_	_
55	'	_	PUNCT	_	_	_	_	_	_
56	NF	_	PROPN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
59	binding	_	NOUN	_	Number=Sing	_	_	_	_
60	site	_	NOUN	_	Number=Sing	_	_	_	_
61	than	_	ADP	_	_	_	_	_	_
62	to	_	ADP	_	_	_	_	_	_
63	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
64	5	_	NUM	_	NumType=Card	_	_	_	_
65	'	_	PUNCT	_	_	_	_	_	_
66	NF	_	PROPN	_	Number=Sing	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
69	site	_	NOUN	_	Number=Sing	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	deletion	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	either	_	CCONJ	_	_	_	_	_	_
6	5	_	NUM	_	NumType=Card	_	_	_	_
7	'	_	NOUN	_	Number=Plur	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	'	_	PUNCT	_	Number=Plur	_	_	_	_
11	NF	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
14	sites	_	NOUN	_	Number=Plur	_	_	_	_
15	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	MT	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
36	NF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	Tax	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	general	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	Tax	_	NOUN	_	Number=Sing	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	pathway	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	productively	_	ADV	_	_	_	_	_	_
11	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	may	_	AUX	_	VerbForm=Fin	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	important	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	hypercalcemia	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	osteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	bone	_	NOUN	_	Number=Sing	_	_	_	_
22	lesions	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	neutrophilia	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	elevation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	C	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	fever	_	NOUN	_	Number=Sing	_	_	_	_
35	frequently	_	ADV	_	_	_	_	_	_
36	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	patients	_	NOUN	_	Number=Sing	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	I-induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	adult	_	NOUN	_	Number=Sing	_	_	_	_
44	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
45	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
46	/	_	PUNCT	_	_	_	_	_	_
47	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012679	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	12	_	NUM	_	NumType=Card	_	_	_	_
4	induces	_	NOUN	_	Number=Plur	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	IRF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	_	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	NK	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	12	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	critical	_	ADJ	_	Degree=Pos	_	_	_	_
7	immunoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	immune	_	ADJ	_	Number=Sing	_	_	_	_
15	responses	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	naive	_	ADJ	_	Degree=Pos	_	_	_	_
21	CD4	_	NOUN	_	Number=Sing	_	_	_	_
22	+	_	SYM	_	_	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	;	_	PUNCT	_	_	_	_	_	_
28	however	_	ADV	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	relatively	_	ADV	_	_	_	_	_	_
31	few	_	ADJ	_	Degree=Pos	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	12	_	NUM	_	NumType=Card	_	_	_	_
35	target	_	NOUN	_	Number=Sing	_	_	_	_
36	genes	_	NOUN	_	Number=Plur	_	_	_	_
37	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
38	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
39	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	better	_	ADV	_	Degree=Cmp	_	_	_	_
3	clarify	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	basis	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	12	_	NUM	_	NumType=Card	_	_	_	_
11	action	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	set	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	out	_	ADP	_	_	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	up	_	ADP	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	12	_	NUM	_	NumType=Card	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	first	_	ADV	_	_	_	_	_	_
28	by	_	SCONJ	_	_	_	_	_	_
29	contrasting	_	VERB	_	VerbForm=Ger	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	12	_	NUM	_	NumType=Card	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	IFN	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
40	genes	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	several	_	ADJ	_	Degree=Pos	_	_	_	_
4	genes	_	NOUN	_	Number=Plur	_	_	_	_
5	up	_	ADP	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	12	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	namely	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	MIP	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1alpha	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	MIP	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1beta	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1RA	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	IFN	_	PROPN	_	Number=Sing	_	_	_	_
29	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	IRF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	IRF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	IFNs	_	NOUN	_	Number=Plur	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	essential	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	Th1	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	responses	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	12	_	NUM	_	NumType=Card	_	_	_	_
7	directly	_	ADV	_	_	_	_	_	_
8	up	_	ADV	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	IRF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	same	_	ADJ	_	Degree=Pos	_	_	_	_
17	extent	_	NOUN	_	Number=Sing	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	IFN	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	normal	_	ADJ	_	Degree=Pos	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	NK	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	12	_	NUM	_	NumType=Card	_	_	_	_
7	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	direct	_	ADJ	_	Degree=Pos	_	_	_	_
10	effect	_	NOUN	_	Number=Sing	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	IRF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	effect	_	NOUN	_	Number=Sing	_	_	_	_
18	not	_	ADV	_	_	_	_	_	_
19	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	indirectly	_	ADV	_	_	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	induction	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	IFN	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	gamma	_	NOUN	_	Number=Sing	_	_	_	_
28	production	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	12	_	NUM	_	NumType=Card	_	_	_	_
10	synergistically	_	ADV	_	_	_	_	_	_
11	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	IRF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	whereas	_	SCONJ	_	_	_	_	_	_
17	IFN	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	12	_	NUM	_	NumType=Card	_	_	_	_
24	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	participation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	STAT4	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IRF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	two	_	NUM	_	NumType=Card	_	_	_	_
16	ways	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	First	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	STAT4	_	PROPN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	12	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	IRF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	reporter	_	NOUN	_	Number=Sing	_	_	_	_
20	construct	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	second	_	ADV	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	STAT4	_	PROPN	_	Number=Sing	_	_	_	_
26	binding	_	VERB	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	IRF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	promoter	_	NOUN	_	Number=Sing	_	_	_	_
33	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
34	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	using	_	VERB	_	VerbForm=Ger	_	_	_	_
36	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	12	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	no	_	DET	_	_	_	_	_	_
9	up	_	ADP	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IRF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	4	_	NUM	_	NumType=Card	_	_	_	_
30	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	not	_	PART	_	_	_	_	_	_
32	block	_	VERB	_	VerbForm=Inf	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	12	_	NUM	_	NumType=Card	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
38	up	_	ADP	_	_	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	regulation	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	IRF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IRF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	contributor	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	12	_	NUM	_	NumType=Card	_	_	_	_
15	signaling	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	speculate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	defective	_	ADJ	_	Degree=Pos	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	12	_	NUM	_	NumType=Card	_	_	_	_
26	responses	_	NOUN	_	Number=Plur	_	_	_	_
27	seen	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	IRF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1-/-	_	PUNCT	_	_	_	_	_	_
32	mice	_	NOUN	_	Number=Plur	_	_	_	_
33	might	_	AUX	_	VerbForm=Fin	_	_	_	_
34	be	_	AUX	_	VerbForm=Inf	_	_	_	_
35	attributable	_	ADJ	_	Degree=Pos	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	part	_	ADJ	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	absence	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
45	transcription	_	NOUN	_	Number=Sing	_	_	_	_
46	factor	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012688	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	USF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	related	_	ADJ	_	Degree=Pos	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	HIV	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	TF1	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	HIV	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	TF1	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	about	_	ADP	_	_	_	_	_	_
14	60	_	NUM	_	NumType=Card	_	_	_	_
15	bp	_	NOUN	_	Number=Sing	_	_	_	_
16	upstream	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
24	virus	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	HIV	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
34	purified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	from	_	ADP	_	_	_	_	_	_
36	human	_	ADJ	_	Degree=Pos	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	TF1	_	PROPN	_	Number=Sing	_	_	_	_
4	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
7	weight	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	39,000	_	NUM	_	NumType=Card	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HIV	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	TF1	_	NOUN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	HIV	_	PROPN	_	Number=Sing	_	_	_	_
9	long	_	ADJ	_	Degree=Pos	_	_	_	_
10	terminal	_	NOUN	_	Number=Sing	_	_	_	_
11	repeat	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	LTR	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	vitro	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	HIV	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	TF1	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	HIV	_	PROPN	_	Number=Sing	_	_	_	_
10	LTR	_	PROPN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	similar	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	recognized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
19	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	USF	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	adenovirus	_	NOUN	_	Degree=Pos	_	_	_	_
27	major	_	ADJ	_	Degree=Pos	_	_	_	_
28	late	_	ADJ	_	Degree=Pos	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	binding	_	VERB	_	Number=Sing	_	_	_	_
4	properties	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	HIV	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	TF1	_	PROPN	_	Number=Sing	_	_	_	_
9	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	HIV	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	TF1	_	PROPN	_	Number=Sing	_	_	_	_
14	might	_	AUX	_	VerbForm=Fin	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	identical	_	ADJ	_	Degree=Pos	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	related	_	ADJ	_	Degree=Pos	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	USF	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	treatment	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	HIV	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	TF1	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
11	greatly	_	ADV	_	_	_	_	_	_
12	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	DNA	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	HIV	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	TF1	_	PROPN	_	Number=Sing	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	essential	_	ADJ	_	Degree=Pos	_	_	_	_
28	for	_	ADP	_	_	_	_	_	_
29	DNA	_	PROPN	_	Number=Sing	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	disruption	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	HIV	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	TF1	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	60	_	NUM	_	NumType=Card	_	_	_	_
13	%	_	SYM	_	Number=Sing	_	_	_	_
14	decrease	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	level	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	HIV	_	NOUN	_	Number=Sing	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	vivo	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	HIV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	TF1	_	PROPN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	involved	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	HIV	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1.	_	NUM	_	NumType=Card	_	_	_	_
17	Document	_	NOUN	_	Number=Sing	_	_	_	_
18	0030012693	_	NUM	_	NumType=Card	_	_	_	_
19	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	essential	_	ADJ	_	Degree=Pos	_	_	_	_
3	role	_	NOUN	_	Number=Sing	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	CD34	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	+	_	SYM	_	_	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	bone	_	VERB	_	NumType=Card	_	_	_	_
15	marrow	_	NOUN	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	survival	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	T	_	NUM	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	maturation	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
25	virus	_	NOUN	_	Number=Sing	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	role	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	SCONJ	_	_	_	_	_	_
32	alternatively	_	ADV	_	_	_	_	_	_
33	mediating	_	VERB	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	protecting	_	VERB	_	VerbForm=Ger	_	_	_	_
36	against	_	ADP	_	_	_	_	_	_
37	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	variety	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	types	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	CD34	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	+	_	SYM	_	_	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	bone	_	VERB	_	Degree=Pos	_	_	_	_
16	marrow	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
21	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	evidence	_	NOUN	_	Number=Sing	_	_	_	_
4	here	_	ADV	_	PronType=Dem	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	virtually	_	ADV	_	_	_	_	_	_
7	all	_	DET	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	CD34	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	+	_	SYM	_	_	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	bone	_	VERB	_	Degree=Pos	_	_	_	_
14	marrow	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	express	_	VERB	_	Degree=Pos	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	can	_	AUX	_	VerbForm=Fin	_	_	_	_
22	be	_	AUX	_	VerbForm=Inf	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	exposure	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
28	12	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	myristate	_	NOUN	_	Number=Sing	_	_	_	_
31	13	_	NUM	_	NumType=Card	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	acetate	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	variety	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	eg	_	NOUN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	tumor	_	NOUN	_	Number=Sing	_	_	_	_
43	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
44	factor	_	NOUN	_	Number=Sing	_	_	_	_
45	alpha	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	3	_	NUM	_	NumType=Card	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	granulocyte	_	ADJ	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
55	colony	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
58	factor	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	CD34	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	+	_	SYM	_	_	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	bone	_	VERB	_	Degree=Pos	_	_	_	_
20	marrow	_	NOUN	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	clonogenic	_	NOUN	_	Number=Sing	_	_	_	_
23	function	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	survival	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	offer	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	insight	_	NOUN	_	Number=Sing	_	_	_	_
5	into	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	new	_	ADJ	_	Degree=Pos	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	SCONJ	_	_	_	_	_	_
14	maintaining	_	VERB	_	VerbForm=Ger	_	_	_	_
15	survival	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	function	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
20	stem	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	proposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	strategies	_	NOUN	_	Number=Plur	_	_	_	_
29	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
30	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
35	activation	_	NOUN	_	Number=Sing	_	_	_	_
36	as	_	ADP	_	_	_	_	_	_
37	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	adjunct	_	NOUN	_	Number=Sing	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	cancer	_	NOUN	_	Number=Sing	_	_	_	_
41	chemotherapy	_	NOUN	_	Number=Sing	_	_	_	_
42	should	_	AUX	_	VerbForm=Fin	_	_	_	_
43	be	_	AUX	_	VerbForm=Inf	_	_	_	_
44	approached	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	with	_	ADP	_	_	_	_	_	_
46	caution	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012698	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	x	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	L	_	X	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
13	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	type	_	NOUN	_	Number=Sing	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	Tax	_	NOUN	_	Number=Sing	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
26	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
27	transfectants	_	NOUN	_	Number=Plur	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	Tax	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	play	_	VERB	_	VerbForm=Inf	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	pivotal	_	ADJ	_	Degree=Pos	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	recently	_	ADV	_	_	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Tax	_	NOUN	_	Number=Sing	_	_	_	_
10	protected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	mouse	_	NOUN	_	Number=Sing	_	_	_	_
13	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
14	line	_	NOUN	_	Number=Sing	_	_	_	_
15	CTLL	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	against	_	ADP	_	_	_	_	_	_
19	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	_	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	deprivation	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	converted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	growth	_	NOUN	_	Number=Sing	_	_	_	_
35	from	_	SCONJ	_	_	_	_	_	_
36	being	_	AUX	_	VerbForm=Ger	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
41	to	_	SCONJ	_	_	_	_	_	_
42	being	_	AUX	_	VerbForm=Ger	_	_	_	_
43	IL	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	2	_	NUM	_	NumType=Card	_	_	_	_
46	independent	_	ADJ	_	Degree=Pos	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	bcl	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	xl	_	NOUN	_	Number=Sing	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	bcl	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	bcl	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	xs	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	bak	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	bad	_	ADJ	_	Degree=Pos	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	bax	_	NOUN	_	Number=Sing	_	_	_	_
30	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
31	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	apoptosis	_	ADJ	_	Number=Sing	_	_	_	_
34	resistance	_	NOUN	_	Number=Sing	_	_	_	_
35	after	_	ADP	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	deprivation	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	CTLL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	2	_	NUM	_	NumType=Card	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	that	_	PRON	_	PronType=Rel	_	_	_	_
46	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
47	Tax	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	transfection	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	bcl	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	x	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	transactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	wild	_	ADJ	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	type	_	NOUN	_	Number=Sing	_	_	_	_
17	Tax	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
7	Tax	_	PROPN	_	Number=Sing	_	_	_	_
8	retaining	_	VERB	_	VerbForm=Ger	_	_	_	_
9	transactivating	_	NOUN	_	Number=Sing	_	_	_	_
10	ability	_	NOUN	_	Number=Sing	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	or	_	CCONJ	_	_	_	_	_	_
3	substitution	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	putative	_	ADJ	_	Degree=Pos	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	bcl	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	x	_	NOUN	_	_	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	significantly	_	ADV	_	_	_	_	_	_
20	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	Tax	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	like	_	ADJ	_	Degree=Pos	_	_	_	_
7	element	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	able	_	ADJ	_	Degree=Pos	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	form	_	VERB	_	VerbForm=Inf	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	complex	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	family	_	NOUN	_	Number=Sing	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	vitro	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Tax	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	bcl	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	x	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	diminished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	mutant	_	ADJ	_	Number=Sing	_	_	_	_
19	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	specifically	_	ADV	_	_	_	_	_	_
23	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	x	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	L	_	X	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	Tax	_	NOUN	_	Number=Sing	_	_	_	_
17	through	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	pathway	_	NOUN	_	Number=Sing	_	_	_	_
23	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	CTLL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	after	_	ADP	_	_	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	deprivation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012699	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Reactivation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	Kaposi	_	PROPN	_	Number=Sing	_	_	_	_
4	's	_	PART	_	_	_	_	_	_
5	sarcoma	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
9	infection	_	NOUN	_	Number=Sing	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	latency	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	ORF	_	PROPN	_	Number=Sing	_	_	_	_
17	50	_	NUM	_	NumType=Card	_	_	_	_
18	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	homolog	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	EBV	_	PROPN	_	Number=Sing	_	_	_	_
25	R	_	NOUN	_	Number=Sing	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Kaposi	_	PROPN	_	Number=Sing	_	_	_	_
2	's	_	PART	_	_	_	_	_	_
3	sarcoma	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	KS	_	PROPN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	KSHV	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	herpesvirus	_	NOUN	_	Number=Sing	_	_	_	_
17	8	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	lymphotropic	_	ADJ	_	Degree=Pos	_	_	_	_
22	virus	_	NOUN	_	Number=Sing	_	_	_	_
23	strongly	_	ADV	_	_	_	_	_	_
24	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	several	_	ADJ	_	Degree=Pos	_	_	_	_
27	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	related	_	ADJ	_	Degree=Pos	_	_	_	_
30	neoplasms	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	primary	_	ADJ	_	Degree=Pos	_	_	_	_
3	reservoir	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	infection	_	NOUN	_	Number=Sing	_	_	_	_
6	consists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	latently	_	ADV	_	_	_	_	_	_
9	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	possibly	_	ADV	_	_	_	_	_	_
14	other	_	ADJ	_	Degree=Pos	_	_	_	_
15	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Viral	_	ADJ	_	Degree=Pos	_	_	_	_
2	reactivation	_	NOUN	_	Number=Sing	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	latency	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	spread	_	VERB	_	Number=Sing	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
10	reservoir	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	presumably	_	ADV	_	_	_	_	_	_
13	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	development	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	nonlymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
18	tumors	_	NOUN	_	Number=Plur	_	_	_	_
19	like	_	ADP	_	_	_	_	_	_
20	KS	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	DET	_	_	_	_	_	_
5	deregulated	_	VERB	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	single	_	ADJ	_	Degree=Pos	_	_	_	_
10	viral	_	ADJ	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	ORF	_	PROPN	_	Number=Sing	_	_	_	_
14	50	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	which	_	PRON	_	PronType=Rel	_	_	_	_
17	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	transactivator	_	NOUN	_	Number=Sing	_	_	_	_
20	able	_	ADJ	_	Degree=Pos	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	selectively	_	ADV	_	_	_	_	_	_
23	upregulate	_	VERB	_	Degree=Pos	_	_	_	_
24	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	early	_	ADJ	_	Degree=Pos	_	_	_	_
27	viral	_	ADJ	_	Degree=Pos	_	_	_	_
28	genes	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	suffices	_	NOUN	_	Number=Plur	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	disrupt	_	VERB	_	VerbForm=Inf	_	_	_	_
33	latency	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	lytic	_	ADJ	_	Degree=Pos	_	_	_	_
38	gene	_	NOUN	_	Number=Sing	_	_	_	_
39	cascade	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	latently	_	ADV	_	_	_	_	_	_
42	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	B	_	ADJ	_	Number=Sing	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	identification	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	opens	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	way	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	studies	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	physiologic	_	ADJ	_	Degree=Pos	_	_	_	_
14	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
15	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
16	reactvation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	KSHV	_	NOUN	_	Number=Sing	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	latency	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1998	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012709	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	Barr	_	PROPN	_	Number=Sing	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_

1	B	_	NOUN	_	Number=Sing	_	_	_	_
2	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	chi	_	NOUN	_	Number=Sing	_	_	_	_
10	B.	_	VERB	_	Number=Sing	_	_	_	_
11	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	mainly	_	ADV	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	T	_	PROPN	_	Number=Sing	_	_	_	_
28	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	predominant	_	ADJ	_	Degree=Pos	_	_	_	_
32	producers	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_
38	However	_	ADV	_	_	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	B	_	PROPN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	can	_	AUX	_	VerbForm=Fin	_	_	_	_
43	also	_	ADV	_	_	_	_	_	_
44	synthesize	_	VERB	_	VerbForm=Inf	_	_	_	_
45	IL	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	2	_	NUM	_	NumType=Card	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	control	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	Barr	_	PROPN	_	Number=Sing	_	_	_	_
19	virus	_	PROPN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	EBV	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	clones	_	NOUN	_	Number=Plur	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	capable	_	ADJ	_	Degree=Pos	_	_	_	_
31	of	_	SCONJ	_	_	_	_	_	_
32	secreting	_	VERB	_	VerbForm=Ger	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	at	_	ADP	_	_	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	low	_	ADJ	_	Degree=Pos	_	_	_	_
39	level	_	NOUN	_	Number=Sing	_	_	_	_
40	after	_	ADP	_	_	_	_	_	_
41	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
42	with	_	ADP	_	_	_	_	_	_
43	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
44	12	_	NUM	_	NumType=Card	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	myristate	_	NOUN	_	Number=Sing	_	_	_	_
47	13	_	NUM	_	NumType=Card	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	acetate	_	NOUN	_	Number=Sing	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
53	+	_	SYM	_	_	_	_	_	_
54	ionophore	_	ADJ	_	Number=Sing	_	_	_	_
55	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	transfections	_	NOUN	_	Number=Plur	_	_	_	_
3	using	_	VERB	_	VerbForm=Ger	_	_	_	_
4	reporter	_	NOUN	_	Number=Sing	_	_	_	_
5	constructs	_	VERB	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	multiples	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	[	_	PUNCT	_	_	_	_	_	_
20	distal	_	ADJ	_	Degree=Pos	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	AT	_	ADP	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	proximal	_	ADJ	_	Number=Sing	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	AT	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	AP	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1/Octamer	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	UPS	_	NOUN	_	Number=Plur	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	or	_	CCONJ	_	_	_	_	_	_
41	NF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	chi	_	PROPN	_	Number=Sing	_	_	_	_
44	B	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	TCEd	_	ADJ	_	Number=Sing	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	sites	_	NOUN	_	Number=Plur	_	_	_	_
49	]	_	PUNCT	_	_	_	_	_	_
50	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
51	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	EBV	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	B	_	PROPN	_	Number=Sing	_	_	_	_
6	clones	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	chi	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	exerted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	strongest	_	ADJ	_	Degree=Sup	_	_	_	_
15	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	;	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	AT	_	ADP	_	_	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	sites	_	NOUN	_	Number=Plur	_	_	_	_
24	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	either	_	CCONJ	_	_	_	_	_	_
26	no	_	DET	_	_	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	only	_	ADV	_	_	_	_	_	_
29	weak	_	ADJ	_	Degree=Pos	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
34	T	_	PROPN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	bearing	_	VERB	_	VerbForm=Ger	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	defective	_	ADJ	_	Degree=Pos	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	chi	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	completely	_	ADV	_	_	_	_	_	_
16	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	EBV	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	B	_	ADJ	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	while	_	SCONJ	_	_	_	_	_	_
25	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
26	still	_	ADV	_	_	_	_	_	_
27	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
31	T	_	PROPN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	seven	_	NUM	_	NumType=Card	_	_	_	_
3	EBV	_	PROPN	_	Number=Sing	_	_	_	_
4	-B	_	NOUN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	clones	_	NOUN	_	Number=Plur	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	differing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	capacity	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	secrete	_	VERB	_	VerbForm=Inf	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	well	_	ADV	_	Degree=Pos	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	status	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	secretion	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Similarly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
6	virus	_	NOUN	_	Number=Sing	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	through	_	ADP	_	_	_	_	_	_
14	chi	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	active	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
29	EBV	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	non-IL	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	2	_	NUM	_	NumType=Card	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	using	_	VERB	_	VerbForm=Ger	_	_	_	_
6	protein	_	NOUN	_	Number=Sing	_	_	_	_
7	extracts	_	NOUN	_	Number=Plur	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	EBV	_	PROPN	_	Number=Sing	_	_	_	_
10	-B	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	chi	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	PROPN	_	Number=Sing	_	_	_	_
21	probe	_	NOUN	_	Number=Sing	_	_	_	_
22	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
25	generation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	chi	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	complexes	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	secreting	_	VERB	_	Degree=Pos	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	consisting	_	VERB	_	VerbForm=Ger	_	_	_	_
38	mainly	_	ADV	_	_	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	heterodimeric	_	ADJ	_	Degree=Pos	_	_	_	_
41	p50	_	NOUN	_	Number=Sing	_	_	_	_
42	/	_	PUNCT	_	_	_	_	_	_
43	p65	_	NOUN	_	Number=Sing	_	_	_	_
44	complexes	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	weaker	_	NOUN	_	Number=Sing	_	_	_	_
3	chi	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	complex	_	ADJ	_	Degree=Pos	_	_	_	_
6	formation	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	faster	_	ADJ	_	Degree=Cmp	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	migrating	_	NOUN	_	Number=Sing	_	_	_	_
11	complexes	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	non-IL	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	secreting	_	VERB	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	chi	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	indispensable	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	EBV	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	B	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	whereas	_	SCONJ	_	_	_	_	_	_
33	other	_	ADJ	_	Degree=Pos	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	factors	_	NOUN	_	Number=Plur	_	_	_	_
36	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
37	to	_	PART	_	_	_	_	_	_
38	be	_	AUX	_	VerbForm=Inf	_	_	_	_
39	less	_	ADV	_	Degree=Cmp	_	_	_	_
40	important	_	ADJ	_	Degree=Pos	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	IL	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	2	_	NUM	_	NumType=Card	_	_	_	_
45	expression	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012712	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Prostaglandin	_	PROPN	_	Number=Sing	_	_	_	_

1	E2	_	PROPN	_	Number=Sing	_	_	_	_
2	Up	_	ADP	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	long	_	ADJ	_	Degree=Pos	_	_	_	_
9	terminal	_	NOUN	_	Number=Sing	_	_	_	_
10	repeat	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	via	_	ADP	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	independent	_	ADJ	_	Degree=Pos	_	_	_	_
27	signaling	_	NOUN	_	Number=Sing	_	_	_	_
28	pathways	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Replication	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	highly	_	ADV	_	_	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	state	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	modulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	interactions	_	NOUN	_	Number=Plur	_	_	_	_
31	between	_	ADP	_	_	_	_	_	_
32	viral	_	ADJ	_	Degree=Pos	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	host	_	VERB	_	Number=Sing	_	_	_	_
35	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
36	factors	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Prostaglandin	_	PROPN	_	Number=Sing	_	_	_	_
2	E2	_	NUM	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	PGE2	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	pleiotropic	_	ADJ	_	Degree=Pos	_	_	_	_
9	immunomodulatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	molecule	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	levels	_	NOUN	_	Number=Plur	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	infection	_	NOUN	_	Number=Sing	_	_	_	_
22	as	_	ADV	_	_	_	_	_	_
23	well	_	ADV	_	Degree=Pos	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	during	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	course	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	other	_	ADJ	_	Degree=Pos	_	_	_	_
30	pathogenic	_	ADJ	_	Degree=Pos	_	_	_	_
31	infections	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	1G5	_	NUM	_	NumType=Card	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	stably	_	ADV	_	_	_	_	_	_
12	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	HIV	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	long	_	ADJ	_	Degree=Pos	_	_	_	_
23	terminal	_	NOUN	_	Number=Sing	_	_	_	_
24	repeat	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	LTR	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
30	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
31	that	_	SCONJ	_	_	_	_	_	_
32	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
33	markedly	_	ADV	_	_	_	_	_	_
34	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	HIV	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	LTR	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	reporter	_	NOUN	_	Number=Sing	_	_	_	_
42	gene	_	NOUN	_	Number=Sing	_	_	_	_
43	activity	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Experiments	_	NOUN	_	Number=Plur	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	conducted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
7	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
8	messengers	_	NOUN	_	Number=Plur	_	_	_	_
9	involved	_	ADJ	_	Degree=Pos	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
12	PGE2	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	up	_	ADP	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	effect	_	NOUN	_	Number=Sing	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	element	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	HIV	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	present	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	evidence	_	NOUN	_	Number=Sing	_	_	_	_
8	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	that	_	DET	_	_	_	_	_	_
10	signal	_	NOUN	_	Number=Sing	_	_	_	_
11	transduction	_	NOUN	_	Number=Sing	_	_	_	_
12	pathways	_	NOUN	_	Number=Plur	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
16	necessitate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	participation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	cyclic	_	ADJ	_	Degree=Pos	_	_	_	_
21	AMP	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	kinase	_	NOUN	_	Number=Sing	_	_	_	_
25	A	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
29	+	_	SYM	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Experiments	_	NOUN	_	Number=Plur	_	_	_	_
2	conducted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	different	_	ADJ	_	Degree=Pos	_	_	_	_
5	HIV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	LTR	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	vectors	_	NOUN	_	Number=Plur	_	_	_	_
12	suggested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	mediated	_	VERB	_	Degree=Pos	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	effect	_	NOUN	_	Number=Sing	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
25	transduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	via	_	ADP	_	_	_	_	_	_
27	both	_	CCONJ	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	independent	_	ADJ	_	Degree=Pos	_	_	_	_
36	signaling	_	NOUN	_	Number=Sing	_	_	_	_
37	pathways	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	involvement	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
13	effect	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	further	_	ADV	_	_	_	_	_	_
21	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	using	_	VERB	_	VerbForm=Ger	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
28	encoding	_	NOUN	_	Number=Sing	_	_	_	_
29	vector	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
33	mobility	_	NOUN	_	Number=Sing	_	_	_	_
34	shift	_	NOUN	_	Number=Sing	_	_	_	_
35	assays	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Results	_	NOUN	_	Number=Plur	_	_	_	_
2	from	_	ADP	_	_	_	_	_	_
3	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
4	blot	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	flow	_	VERB	_	Number=Sing	_	_	_	_
7	cytometric	_	ADJ	_	Degree=Pos	_	_	_	_
8	analyses	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	as	_	ADV	_	_	_	_	_	_
11	well	_	ADV	_	Degree=Pos	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	use	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	selective	_	ADJ	_	Degree=Pos	_	_	_	_
18	antagonist	_	NOUN	_	Number=Sing	_	_	_	_
19	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
22	modulation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	HIV	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	LTR	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	reporter	_	NOUN	_	Number=Sing	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	activity	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	studied	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	T	_	PROPN	_	Number=Sing	_	_	_	_
36	lymphoid	_	PROPN	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	transduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	via	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	EP4	_	PROPN	_	Number=Sing	_	_	_	_
43	receptor	_	NOUN	_	Number=Sing	_	_	_	_
44	subtype	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	secretion	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	infection	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	activators	_	NOUN	_	Number=Plur	_	_	_	_
17	could	_	AUX	_	VerbForm=Fin	_	_	_	_
18	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
19	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
20	events	_	NOUN	_	Number=Plur	_	_	_	_
21	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
26	DNA	_	NOUN	_	Number=Sing	_	_	_	_
27	present	_	VERB	_	VerbForm=Inf	_	_	_	_
28	into	_	ADP	_	_	_	_	_	_
29	T	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	latently	_	ADV	_	_	_	_	_	_
32	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	HIV	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_
38	Document	_	NOUN	_	Number=Sing	_	_	_	_
39	0030012716	_	NUM	_	NumType=Card	_	_	_	_
40	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Suppression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	signals	_	NOUN	_	Number=Plur	_	_	_	_
4	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	constitutively	_	ADV	_	_	_	_	_	_
17	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	Tax	_	NOUN	_	Number=Sing	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	short	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	term	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	Tax	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
13	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	type	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	pleiotropic	_	ADJ	_	Degree=Pos	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	PROPN	_	Number=Sing	_	_	_	_
34	B.	_	PROPN	_	Number=Sing	_	_	_	_
35	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	findings	_	NOUN	_	Number=Plur	_	_	_	_
38	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	transient	_	ADJ	_	Degree=Pos	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	assays	_	NOUN	_	Number=Plur	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
45	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
46	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
48	of	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	transcription	_	NOUN	_	Number=Sing	_	_	_	_
51	factor	_	NOUN	_	Number=Sing	_	_	_	_
52	NF	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	kappa	_	NOUN	_	Number=Sing	_	_	_	_
55	B	_	NOUN	_	Number=Sing	_	_	_	_
56	in	_	ADP	_	_	_	_	_	_
57	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
58	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
59	of	_	ADP	_	_	_	_	_	_
60	Namalwa	_	PROPN	_	Number=Sing	_	_	_	_
61	B	_	PROPN	_	Number=Sing	_	_	_	_
62	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
63	cells	_	NOUN	_	Number=Plur	_	_	_	_
64	,	_	PUNCT	_	_	_	_	_	_
65	which	_	PRON	_	PronType=Rel	_	_	_	_
66	constitutively	_	ADV	_	_	_	_	_	_
67	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
68	Tax	_	NOUN	_	Number=Sing	_	_	_	_
69	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
15	following	_	VERB	_	VerbForm=Ger	_	_	_	_
16	long	_	ADJ	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	term	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	Tax	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
24	T	_	PROPN	_	Number=Sing	_	_	_	_
25	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	both	_	DET	_	_	_	_	_	_
5	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	PROPN	_	Number=Sing	_	_	_	_
13	B	_	PROPN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	constitutively	_	ADV	_	_	_	_	_	_
21	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	Tax	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	such	_	ADJ	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	Fos	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	Jun	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	depending	_	VERB	_	VerbForm=Ger	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
7	environment	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	short	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	long	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	term	_	NOUN	_	Number=Sing	_	_	_	_
16	effects	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	Tax	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	can	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	quite	_	ADV	_	_	_	_	_	_
23	different	_	ADJ	_	Degree=Pos	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Consequently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	one	_	NUM	_	NumType=Card	_	_	_	_
4	function	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Tax	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	might	_	AUX	_	VerbForm=Fin	_	_	_	_
15	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	suppression	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	as	_	SCONJ	_	_	_	_	_	_
24	opposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
30	signal	_	NOUN	_	Number=Sing	_	_	_	_
31	pathways	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	lines	_	NOUN	_	Number=Plur	_	_	_	_
4	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	here	_	ADV	_	PronType=Dem	_	_	_	_
6	should	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	useful	_	ADJ	_	Degree=Pos	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	delineation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
14	pathways	_	NOUN	_	Number=Plur	_	_	_	_
15	utilized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	selective	_	ADJ	_	Degree=Pos	_	_	_	_
19	regulation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012719	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Upregulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	bcl	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	Barr	_	PROPN	_	Number=Sing	_	_	_	_
11	virus	_	NOUN	_	Number=Sing	_	_	_	_
12	latent	_	ADJ	_	Degree=Pos	_	_	_	_
13	membrane	_	NOUN	_	Number=Sing	_	_	_	_
14	protein	_	NOUN	_	Number=Sing	_	_	_	_
15	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
16	:	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	B-cell	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	response	_	NOUN	_	Number=Sing	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	delayed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	relative	_	ADV	_	_	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	activation	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	induction	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	surface	_	NOUN	_	Number=Sing	_	_	_	_
38	markers	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	ability	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	Barr	_	PROPN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	latent	_	ADJ	_	Degree=Pos	_	_	_	_
10	membrane	_	NOUN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	survival	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	B	_	ADJ	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	through	_	ADP	_	_	_	_	_	_
22	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	bcl	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
29	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
30	first	_	ADV	_	_	_	_	_	_
31	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	experiments	_	NOUN	_	Number=Plur	_	_	_	_
34	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	transfection	_	NOUN	_	Number=Sing	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	selection	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	stable	_	ADJ	_	Number=Sing	_	_	_	_
42	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
43	+	_	SYM	_	_	_	_	_	_
44	clones	_	NOUN	_	Number=Plur	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	S.	_	PROPN	_	Number=Sing	_	_	_	_
47	Henderson	_	PROPN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	M.	_	PROPN	_	Number=Sing	_	_	_	_
50	Rowe	_	PROPN	_	Number=Sing	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	C.Gregory	_	PROPN	_	Number=Sing	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	F.	_	PROPN	_	Number=Sing	_	_	_	_
55	Wang	_	PROPN	_	Number=Sing	_	_	_	_
56	,	_	PUNCT	_	_	_	_	_	_
57	E.Kieff	_	PROPN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	and	_	CCONJ	_	_	_	_	_	_
60	A.Rickinson	_	PROPN	_	Number=Sing	_	_	_	_
61	,	_	PUNCT	_	_	_	_	_	_
62	Cell	_	NOUN	_	Number=Sing	_	_	_	_
63	65:1107-1115	_	NUM	_	NumType=Card	_	_	_	_
64	,	_	PUNCT	_	_	_	_	_	_
65	1991	_	NUM	_	NumType=Card	_	_	_	_
66	)	_	PUNCT	_	_	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	possible	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	ascertain	_	VERB	_	VerbForm=Inf	_	_	_	_
9	whether	_	SCONJ	_	_	_	_	_	_
10	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	consequence	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	artifact	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	selection	_	NOUN	_	Number=Sing	_	_	_	_
27	procedure	_	NOUN	_	Number=Sing	_	_	_	_
28	whereby	_	ADV	_	_	_	_	_	_
29	rare	_	ADJ	_	Degree=Pos	_	_	_	_
30	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	2	_	NUM	_	NumType=Card	_	_	_	_
33	+	_	SYM	_	_	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	already	_	ADV	_	_	_	_	_	_
36	present	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	starting	_	NOUN	_	Number=Sing	_	_	_	_
40	population	_	NOUN	_	Number=Sing	_	_	_	_
41	might	_	AUX	_	VerbForm=Fin	_	_	_	_
42	best	_	ADV	_	Degree=Sup	_	_	_	_
43	be	_	AUX	_	VerbForm=Inf	_	_	_	_
44	able	_	ADJ	_	Degree=Pos	_	_	_	_
45	to	_	PART	_	_	_	_	_	_
46	tolerate	_	VERB	_	VerbForm=Inf	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	potentially	_	ADV	_	_	_	_	_	_
49	toxic	_	ADJ	_	Degree=Pos	_	_	_	_
50	effects	_	NOUN	_	Number=Plur	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	reexamined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	issue	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	SCONJ	_	_	_	_	_	_
7	using	_	VERB	_	VerbForm=Ger	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	different	_	ADJ	_	Degree=Pos	_	_	_	_
10	experimental	_	ADJ	_	Degree=Pos	_	_	_	_
11	approaches	_	NOUN	_	Number=Plur	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	allowed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	effects	_	NOUN	_	Number=Plur	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	monitored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	immediately	_	ADV	_	_	_	_	_	_
22	following	_	VERB	_	VerbForm=Ger	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	viral	_	ADJ	_	Degree=Pos	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	absence	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	selective	_	ADJ	_	Degree=Pos	_	_	_	_
34	pressures	_	NOUN	_	Number=Plur	_	_	_	_
35	;	_	PUNCT	_	_	_	_	_	_
36	activation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappa	_	NOUN	_	Number=Sing	_	_	_	_
42	B	_	NOUN	_	Number=Sing	_	_	_	_
43	transcription	_	NOUN	_	Number=Sing	_	_	_	_
44	factor	_	NOUN	_	Number=Sing	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	cell	_	NOUN	_	Number=Sing	_	_	_	_
50	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
51	molecule	_	NOUN	_	Number=Sing	_	_	_	_
52	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	1	_	NUM	_	NumType=Card	_	_	_	_
55	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
56	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
57	as	_	ADP	_	_	_	_	_	_
58	early	_	ADJ	_	Degree=Pos	_	_	_	_
59	indices	_	NOUN	_	Number=Plur	_	_	_	_
60	of	_	ADP	_	_	_	_	_	_
61	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
62	function	_	NOUN	_	Number=Sing	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
4	approach	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	stable	_	ADJ	_	Number=Sing	_	_	_	_
7	clones	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	B	_	NOUN	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	lines	_	NOUN	_	Number=Plur	_	_	_	_
14	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	under	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	control	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
24	metallothionein	_	NOUN	_	Number=Sing	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	to	_	PART	_	_	_	_	_	_
29	express	_	VERB	_	VerbForm=Inf	_	_	_	_
30	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	all	_	DET	_	_	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NK	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	within	_	ADP	_	_	_	_	_	_
15	24	_	NUM	_	NumType=Card	_	_	_	_
16	h	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	followed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	48	_	NUM	_	NumType=Card	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	72	_	NUM	_	NumType=Card	_	_	_	_
24	h	_	NOUN	_	Number=Plur	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
4	approach	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	tested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	generality	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
12	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	transiently	_	ADV	_	_	_	_	_	_
15	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	strong	_	ADJ	_	Degree=Pos	_	_	_	_
20	constitutively	_	ADV	_	_	_	_	_	_
21	active	_	ADJ	_	Degree=Pos	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	range	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	different	_	ADJ	_	Degree=Pos	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	types	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	six	_	NUM	_	NumType=Card	_	_	_	_
3	B	_	NOUN	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	lines	_	NOUN	_	Number=Plur	_	_	_	_
7	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	showed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	followed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	five	_	NUM	_	NumType=Card	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	six	_	NUM	_	NumType=Card	_	_	_	_
28	lines	_	NOUN	_	Number=Plur	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	ICAM	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	same	_	ADJ	_	Degree=Pos	_	_	_	_
4	experiments	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	all	_	DET	_	_	_	_	_	_
7	three	_	NUM	_	NumType=Card	_	_	_	_
8	non-B	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	lines	_	NOUN	_	Number=Plur	_	_	_	_
12	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	never	_	ADV	_	_	_	_	_	_
25	any	_	DET	_	_	_	_	_	_
26	effect	_	NOUN	_	Number=Sing	_	_	_	_
27	upon	_	ADP	_	_	_	_	_	_
28	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	part	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	panoply	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
16	changes	_	NOUN	_	Number=Plur	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	effect	_	NOUN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	type	_	NOUN	_	Number=Sing	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	whilst	_	SCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	essential	_	ADJ	_	Degree=Pos	_	_	_	_
15	component	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
18	signal	_	NOUN	_	Number=Sing	_	_	_	_
19	transduction	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	other	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	factors	_	NOUN	_	Number=Plur	_	_	_	_
26	may	_	AUX	_	VerbForm=Fin	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	effect	_	VERB	_	VerbForm=Inf	_	_	_	_
31	some	_	DET	_	_	_	_	_	_
32	functions	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	viral	_	ADJ	_	Degree=Pos	_	_	_	_
36	protein	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012722	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HIV	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	replication	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
17	derivatives	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
5	DNA	_	NOUN	_	Number=Sing	_	_	_	_
6	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	binding	_	NOUN	_	Degree=Pos	_	_	_	_
9	sites	_	NOUN	_	Number=Plur	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	PROPN	_	Number=Sing	_	_	_	_
17	B.	_	PROPN	_	Number=Sing	_	_	_	_
18	HIV	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	individuals	_	NOUN	_	Number=Plur	_	_	_	_
24	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	average	_	ADJ	_	Degree=Pos	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	abnormally	_	ADV	_	_	_	_	_	_
30	high	_	ADJ	_	Degree=Pos	_	_	_	_
31	levels	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	tumour	_	NOUN	_	Number=Sing	_	_	_	_
34	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	alpha	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	TNF	_	PROPN	_	Number=Sing	_	_	_	_
39	alpha	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	abnormally	_	ADV	_	_	_	_	_	_
43	low	_	ADJ	_	Degree=Pos	_	_	_	_
44	plasma	_	NOUN	_	Number=Sing	_	_	_	_
45	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
46	levels	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	related	_	ADJ	_	Degree=Pos	_	_	_	_
10	thiols	_	NOUN	_	Number=Plur	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	replication	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	experiments	_	NOUN	_	Number=Plur	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	report	_	NOUN	_	Number=Sing	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	N-acetylcysteine	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	NAC	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	raise	_	VERB	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
17	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	GSH	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	level	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
24	HIV	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	replication	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	persistently	_	ADV	_	_	_	_	_	_
30	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	Molt	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	4	_	NUM	_	NumType=Card	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	U937	_	NOUN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	replication	_	NOUN	_	Number=Sing	_	_	_	_
9	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	directly	_	ADV	_	_	_	_	_	_
14	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	GSH	_	NOUN	_	Number=Sing	_	_	_	_
17	levels	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Cysteine	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	NAC	_	PROPN	_	Number=Sing	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	as	_	SCONJ	_	_	_	_	_	_
12	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
15	mobility	_	NOUN	_	Number=Sing	_	_	_	_
16	shift	_	NOUN	_	Number=Sing	_	_	_	_
17	assays	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
20	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	transferase	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	CAT	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	under	_	ADP	_	_	_	_	_	_
29	control	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	binding	_	NOUN	_	VerbForm=Ger	_	_	_	_
36	sites	_	NOUN	_	Number=Plur	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	uninfected	_	ADJ	_	Degree=Pos	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
6	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	HIV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	individuals	_	NOUN	_	Number=Plur	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	cause	_	VERB	_	VerbForm=Inf	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	over	_	ADP	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	genes	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
30	HIV	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	replication	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	NAC	_	PROPN	_	Number=Sing	_	_	_	_
2	may	_	AUX	_	VerbForm=Fin	_	_	_	_
3	be	_	AUX	_	VerbForm=Inf	_	_	_	_
4	considered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	treatment	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	individuals	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012723	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HIV	_	NOUN	_	Number=Sing	_	_	_	_
4	replication	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
10	inhibitory	_	NOUN	_	Degree=Pos	_	_	_	_
11	factor	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
8	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	LIF	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
16	virus	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	replication	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	MNP	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	LIF	_	PROPN	_	Number=Sing	_	_	_	_
2	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	dose	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	increase	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	p24	_	NUM	_	Number=Sing	_	_	_	_
10	antigen	_	NOUN	_	Number=Sing	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	chronically	_	ADV	_	_	_	_	_	_
15	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	line	_	NOUN	_	Number=Sing	_	_	_	_
19	U1	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	time	_	NOUN	_	Number=Sing	_	_	_	_
5	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	LIF	_	PROPN	_	Number=Sing	_	_	_	_
9	effects	_	NOUN	_	Number=Plur	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	similar	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	6	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	tumor	_	NOUN	_	Number=Sing	_	_	_	_
27	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	TNF	_	PROPN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	other	_	ADJ	_	Degree=Pos	_	_	_	_
34	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
35	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
38	HIV	_	NOUN	_	Number=Sing	_	_	_	_
39	replication	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	line	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	characterize	_	VERB	_	VerbForm=Inf	_	_	_	_
3	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
4	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	LIF	_	NOUN	_	Number=Sing	_	_	_	_
8	effects	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	DNA	_	PROPN	_	Number=Sing	_	_	_	_
19	binding	_	VERB	_	Number=Sing	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kB	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	signal	_	NOUN	_	Number=Sing	_	_	_	_
30	transduction	_	NOUN	_	Number=Sing	_	_	_	_
31	pathways	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	potential	_	ADJ	_	Degree=Pos	_	_	_	_
35	interactions	_	NOUN	_	Number=Plur	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	other	_	ADJ	_	Degree=Pos	_	_	_	_
38	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
39	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	LIF	_	PROPN	_	Number=Sing	_	_	_	_
2	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	steady	_	ADJ	_	Degree=Pos	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	state	_	NOUN	_	Number=Sing	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	2.0	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	4.3	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	9.2	_	NUM	_	NumType=Card	_	_	_	_
17	kB	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	24	_	NUM	_	NumType=Card	_	_	_	_
6	h	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	persisted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	until	_	ADP	_	_	_	_	_	_
10	72	_	NUM	_	NumType=Card	_	_	_	_
11	h	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	DNA	_	PROPN	_	Number=Sing	_	_	_	_
3	binding	_	VERB	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kB	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	central	_	ADJ	_	Degree=Pos	_	_	_	_
11	mediator	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	cytokine	_	ADJ	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kB	_	NOUN	_	Number=Sing	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
9	U1	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	as	_	SCONJ	_	_	_	_	_	_
12	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	parent	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	line	_	NOUN	_	Number=Sing	_	_	_	_
18	U937	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	both	_	DET	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	LIF	_	PROPN	_	Number=Sing	_	_	_	_
6	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	NF	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kB	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kB	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	replication	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	at	_	ADV	_	_	_	_	_	_
13	least	_	ADV	_	Degree=Sup	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	part	_	ADJ	_	Degree=Pos	_	_	_	_
16	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
19	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
20	intermediates	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
3	radical	_	ADJ	_	Degree=Pos	_	_	_	_
4	scavenger	_	NOUN	_	Number=Sing	_	_	_	_
5	N	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	acetyl	_	PROPN	_	Number=Sing	_	_	_	_
8	-L	_	PUNCT	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	cysteine	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	nitric	_	ADJ	_	Degree=Pos	_	_	_	_
18	oxide	_	NOUN	_	Number=Sing	_	_	_	_
19	synthase	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	LIF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	replication	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	LIF	_	PROPN	_	Number=Sing	_	_	_	_
2	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	production	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	but	_	CCONJ	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	effects	_	NOUN	_	Number=Plur	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	HIV	_	NOUN	_	Number=Sing	_	_	_	_
15	replication	_	NOUN	_	Number=Sing	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	not	_	PART	_	_	_	_	_	_
18	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	TNF	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	6	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	LIF	_	PROPN	_	Number=Sing	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	replication	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	0030012733	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	PROPN	_	Number=Sing	_	_	_	_
14	p50	_	NUM	_	Number=Sing	_	_	_	_
15	subunit	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	underlies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	self	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	perpetuation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
25	virus	_	NOUN	_	Number=Sing	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
3	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
4	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	translocation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	U937	_	PROPN	_	Number=Sing	_	_	_	_
17	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	chronically	_	ADV	_	_	_	_	_	_
20	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
24	virus	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	HIV	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
29	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	p105	_	NUM	_	Number=Sing	_	_	_	_
12	precursor	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	PROPN	_	Number=Sing	_	_	_	_
19	p50	_	PROPN	_	Number=Sing	_	_	_	_
20	subunit	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Deletions	_	NOUN	_	Number=Plur	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	through	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B-	_	NOUN	_	Number=Sing	_	_	_	_
17	but	_	CCONJ	_	_	_	_	_	_
18	not	_	ADV	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	motif	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	bona	_	NOUN	_	Number=Sing	_	_	_	_
29	fide	_	NOUN	_	Number=Sing	_	_	_	_
30	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
31	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
4	extracts	_	NOUN	_	Number=Plur	_	_	_	_
5	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	transient	_	ADJ	_	Degree=Pos	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
14	ester	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	permanent	_	ADJ	_	Degree=Pos	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	translocation	_	NOUN	_	Number=Sing	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	HIV	_	PROPN	_	Number=Sing	_	_	_	_
26	infection	_	NOUN	_	Number=Sing	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
30	on	_	ADP	_	_	_	_	_	_
31	PKC	_	PROPN	_	Number=Sing	_	_	_	_
32	isoenzymes	_	NOUN	_	Number=Plur	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	beta	_	PROPN	_	Number=Sing	_	_	_	_
36	as	_	SCONJ	_	_	_	_	_	_
37	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	use	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
43	specific	_	ADJ	_	Degree=Pos	_	_	_	_
44	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	GF	_	PROPN	_	Number=Sing	_	_	_	_
47	109203X	_	NUM	_	NumType=Card	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	during	_	ADP	_	_	_	_	_	_
6	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
7	HIV	_	NOUN	_	Number=Sing	_	_	_	_
8	infection	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	U937	_	NUM	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	continuous	_	ADJ	_	Degree=Pos	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	p50	_	NOUN	_	NumType=Card	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	p65	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	translocation	_	NOUN	_	Number=Sing	_	_	_	_
24	results	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	p105	_	NOUN	_	Number=Sing	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
31	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappa	_	NOUN	_	Number=Sing	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	ready	_	ADJ	_	Degree=Pos	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	further	_	ADJ	_	Degree=Pos	_	_	_	_
41	translocation	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	HIV	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	mediated	_	VERB	_	Degree=Pos	_	_	_	_
5	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
6	results	_	NOUN	_	Number=Plur	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	self	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	perpetuating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	loop	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	production	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012734	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	murine	_	NOUN	_	Number=Sing	_	_	_	_
5	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
8	kinase	_	NOUN	_	Number=Sing	_	_	_	_
9	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	p27Kip1	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
7	p27Kip1	_	NOUN	_	Number=Sing	_	_	_	_
8	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	important	_	ADJ	_	Degree=Pos	_	_	_	_
11	role	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	SCONJ	_	_	_	_	_	_
13	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	cycle	_	NOUN	_	Number=Sing	_	_	_	_
17	progression	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	p27Kip1	_	NOUN	_	Number=Sing	_	_	_	_
2	directly	_	ADV	_	_	_	_	_	_
3	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	catalytic	_	ADJ	_	Degree=Pos	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	cdks	_	NOUN	_	Number=Plur	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	complexes	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	interferes	_	VERB	_	Number=Plur	_	_	_	_
22	physically	_	ADV	_	_	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	cdks	_	NOUN	_	Number=Plur	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	CAK	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	level	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	p27Kip1	_	NOUN	_	Number=Sing	_	_	_	_
8	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	SCONJ	_	_	_	_	_	_
12	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	Go	_	VERB	_	Number=Sing	_	_	_	_
14	T-cells	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	rapidly	_	ADV	_	_	_	_	_	_
17	declined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	following	_	VERB	_	VerbForm=Ger	_	_	_	_
19	anti-CD3	_	ADJ	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	here	_	ADV	_	PronType=Dem	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	cloning	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	p27Kip1	_	NOUN	_	Degree=Pos	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	murine	_	ADJ	_	Number=Sing	_	_	_	_
11	genomic	_	ADJ	_	Degree=Pos	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	functional	_	ADJ	_	Degree=Pos	_	_	_	_
16	analysis	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	p27Kip1	_	NOUN	_	Degree=Pos	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	consists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	at	_	ADV	_	_	_	_	_	_
6	least	_	ADV	_	Degree=Sup	_	_	_	_
7	three	_	NUM	_	NumType=Card	_	_	_	_
8	exons	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	spans	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	more	_	ADJ	_	Degree=Cmp	_	_	_	_
12	than	_	ADP	_	_	_	_	_	_
13	5.6	_	NUM	_	NumType=Card	_	_	_	_
14	kb	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Primer	_	ADJ	_	Number=Sing	_	_	_	_
2	extension	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	nuclease	_	NOUN	_	Number=Sing	_	_	_	_
5	S1	_	NOUN	_	Number=Sing	_	_	_	_
6	protection	_	NOUN	_	Number=Sing	_	_	_	_
7	analysis	_	NOUN	_	Number=Sing	_	_	_	_
8	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	major	_	ADJ	_	Degree=Pos	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	initiation	_	NOUN	_	Number=Sing	_	_	_	_
13	sites	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	promoter	_	NOUN	_	Number=Sing	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	lacked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	TATA	_	NOUN	_	Number=Sing	_	_	_	_
7	box	_	NOUN	_	Number=Sing	_	_	_	_
8	but	_	CCONJ	_	_	_	_	_	_
9	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	potential	_	ADJ	_	Degree=Pos	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
16	factors	_	NOUN	_	Number=Plur	_	_	_	_
17	including	_	VERB	_	VerbForm=Ger	_	_	_	_
18	two	_	NUM	_	NumType=Card	_	_	_	_
19	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	CRE	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	Myb	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	NFkB	_	PROPN	_	Number=Sing	_	_	_	_
26	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	at	_	ADP	_	_	_	_	_	_
28	positions	_	NOUN	_	Number=Plur	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	153	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	-	_	SYM	_	_	_	_	_	_
33	178	_	NUM	_	NumType=Card	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	-	_	SYM	_	_	_	_	_	_
36	286	_	NUM	_	NumType=Card	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	-	_	SYM	_	_	_	_	_	_
39	875	_	NUM	_	NumType=Card	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	-	_	SYM	_	_	_	_	_	_
43	1011	_	NUM	_	NumType=Card	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	respectively	_	ADV	_	_	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	analyze	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
6	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
7	p27Kip1	_	NOUN	_	Degree=Pos	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	characterized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	5'-	_	NOUN	_	_	_	_	_	_
15	flanking	_	VERB	_	Number=Sing	_	_	_	_
16	region	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	nt	_	PROPN	_	_	_	_	_	_
19	-	_	SYM	_	_	_	_	_	_
20	1609	_	NUM	_	NumType=Card	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	+	_	SYM	_	_	_	_	_	_
23	178	_	NUM	_	NumType=Card	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	326	_	NUM	_	NumType=Card	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	-	_	SYM	_	_	_	_	_	_
6	615	_	NUM	_	NumType=Card	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	positive	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	elements	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012736	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CTLA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4-	_	NUM	_	_	_	_	_	_
4	Mediated	_	ADJ	_	Degree=Pos	_	_	_	_
5	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	early	_	ADJ	_	Degree=Pos	_	_	_	_
8	events	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	CTLA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	engagement	_	NOUN	_	Number=Sing	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	mAbs	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	while	_	SCONJ	_	_	_	_	_	_
10	CD28	_	PROPN	_	Number=Sing	_	_	_	_
11	enhances	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
19	upon	_	ADP	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	CTLA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
15	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	naive	_	ADJ	_	Degree=Pos	_	_	_	_
22	CD4	_	NOUN	_	Number=Sing	_	_	_	_
23	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	using	_	VERB	_	VerbForm=Ger	_	_	_	_
4	Ab	_	PROPN	_	Number=Sing	_	_	_	_
5	cross	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	linking	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	CTLA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	ligation	_	NOUN	_	Number=Sing	_	_	_	_
5	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	CD3	_	PROPN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	CD28	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
15	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	SCONJ	_	_	_	_	_	_
17	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	to	_	PART	_	_	_	_	_	_
26	be	_	AUX	_	VerbForm=Inf	_	_	_	_
27	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	part	_	ADJ	_	Number=Sing	_	_	_	_
30	through	_	ADP	_	_	_	_	_	_
31	decreasing	_	VERB	_	VerbForm=Ger	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	AT	_	ADP	_	_	_	_	_	_
35	accumulation	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CTLA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	4	_	NUM	_	NumType=Card	_	_	_	_
6	ligation	_	NOUN	_	Number=Sing	_	_	_	_
7	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	appear	_	VERB	_	VerbForm=Inf	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	CD28	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
16	stabilization	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CTLA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	4	_	NUM	_	NumType=Card	_	_	_	_
6	engagement	_	NOUN	_	Number=Sing	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	progression	_	NOUN	_	Number=Sing	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	cycle	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	cyclin	_	NOUN	_	Number=Sing	_	_	_	_

1	D3	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
6	kinase	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	cdk	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	cdk6	_	NOUN	_	Number=Sing	_	_	_	_
14	when	_	ADV	_	PronType=Int	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	CD28	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	anti-CD3	_	NOUN	_	Number=Sing	_	_	_	_
27	alone	_	ADV	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CTLA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
9	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
10	events	_	NOUN	_	Number=Plur	_	_	_	_
11	early	_	ADV	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	both	_	CCONJ	_	_	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	at	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	level	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	independent	_	ADJ	_	Degree=Pos	_	_	_	_
32	events	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	cycle	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	not	_	PART	_	_	_	_	_	_
41	simply	_	ADV	_	_	_	_	_	_
42	oppose	_	VERB	_	VerbForm=Inf	_	_	_	_
43	CD28	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	mediated	_	VERB	_	Degree=Pos	_	_	_	_
46	costimulation	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012739	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	oriP	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	essential	_	ADJ	_	Degree=Pos	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	promoter	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Barr	_	PROPN	_	Number=Sing	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	immortalized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	lymphoblastoid	_	ADJ	_	Degree=Pos	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lines	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	During	_	ADP	_	_	_	_	_	_
2	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Barr	_	PROPN	_	Number=Sing	_	_	_	_
5	virus	_	NOUN	_	Number=Sing	_	_	_	_
6	latent	_	ADJ	_	Degree=Pos	_	_	_	_
7	infection	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	B	_	NOUN	_	Degree=Pos	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	vitro	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	six	_	NUM	_	NumType=Card	_	_	_	_
15	viral	_	ADJ	_	Degree=Pos	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	antigens	_	NOUN	_	Number=Plur	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	EBNAs	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	one	_	NUM	_	NumType=Card	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	two	_	NUM	_	NumType=Card	_	_	_	_
27	promoters	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	Cp	_	NOUN	_	Number=Sing	_	_	_	_
30	or	_	CCONJ	_	_	_	_	_	_
31	Wp	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
34	activities	_	NOUN	_	Number=Plur	_	_	_	_
35	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	mutually	_	ADV	_	_	_	_	_	_
37	exclusive	_	ADJ	_	Degree=Pos	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	infection	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	Wp	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	initially	_	ADV	_	_	_	_	_	_
7	active	_	ADJ	_	Degree=Pos	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	switch	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	Cp	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	duration	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	latency	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	region	_	NOUN	_	Number=Sing	_	_	_	_
7	upstream	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Cp	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	presence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	cis	_	NOUN	_	Number=Sing	_	_	_	_
17	elements	_	NOUN	_	Number=Plur	_	_	_	_
18	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
19	in	_	SCONJ	_	_	_	_	_	_
20	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	activities	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
26	gene	_	NOUN	_	Number=Sing	_	_	_	_
27	promoters	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	SCONJ	_	_	_	_	_	_
29	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	vitro	_	NOUN	_	Number=Sing	_	_	_	_
32	immortalized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	lymphoblastoid	_	NOUN	_	Degree=Pos	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	lines	_	NOUN	_	Number=Plur	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	LCLs	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	determined	_	VERB	_	Degree=Pos	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	oriP	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	origin	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	episomal	_	ADJ	_	Degree=Pos	_	_	_	_
11	maintenance	_	NOUN	_	Number=Sing	_	_	_	_
12	during	_	ADP	_	_	_	_	_	_
13	latency	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	essential	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	initiation	_	NOUN	_	Number=Sing	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	either	_	CCONJ	_	_	_	_	_	_
23	Cp	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	Wp	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	LCLs	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	as	_	ADV	_	_	_	_	_	_
30	well	_	ADV	_	Degree=Pos	_	_	_	_
31	as	_	ADP	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	some	_	DET	_	_	_	_	_	_
34	Burkitt	_	NOUN	_	Number=Sing	_	_	_	_
35	's	_	PART	_	_	_	_	_	_
36	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	lines	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	EBNA2	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	upstream	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Cp	_	NOUN	_	Number=Sing	_	_	_	_
12	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	ca	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	two	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	fivefold	_	VERB	_	VerbForm=Inf	_	_	_	_
5	reduction	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	Cp	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	LCLs	_	NOUN	_	Number=Sing	_	_	_	_
12	assayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	More	_	ADV	_	_	_	_	_	_
2	extensive	_	ADJ	_	Degree=Pos	_	_	_	_
3	deletion	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	sequences	_	NOUN	_	Number=Plur	_	_	_	_
6	upstream	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Cp	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	including	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	EBNA2	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	nearly	_	ADV	_	_	_	_	_	_
20	complete	_	ADJ	_	Degree=Pos	_	_	_	_
21	loss	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	Cp	_	NOUN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	loss	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	correlate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	deletion	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	two	_	NUM	_	NumType=Card	_	_	_	_
13	CCAAT	_	NOUN	_	Number=Sing	_	_	_	_
14	boxes	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
18	CCAAT	_	NOUN	_	Number=Sing	_	_	_	_
19	box	_	NOUN	_	Number=Sing	_	_	_	_
20	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	bp	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	61	_	NUM	_	NumType=Card	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	-	_	SYM	_	_	_	_	_	_
27	65	_	NUM	_	NumType=Card	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	distal	_	ADJ	_	Degree=Pos	_	_	_	_
31	CCAAT	_	PROPN	_	Number=Sing	_	_	_	_
32	box	_	NOUN	_	Number=Sing	_	_	_	_
33	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	at	_	ADP	_	_	_	_	_	_
35	bp	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	253	_	NUM	_	NumType=Card	_	_	_	_
38	to	_	ADP	_	_	_	_	_	_
39	-	_	SYM	_	_	_	_	_	_
40	257	_	NUM	_	NumType=Card	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	upstream	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	Cp.	_	PROPN	_	Number=Sing	_	_	_	_
45	Site	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
51	cis	_	NOUN	_	Number=Plur	_	_	_	_
52	elements	_	NOUN	_	Number=Plur	_	_	_	_
53	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
54	that	_	SCONJ	_	_	_	_	_	_
55	Cp	_	NOUN	_	Number=Sing	_	_	_	_
56	activity	_	NOUN	_	Number=Sing	_	_	_	_
57	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
58	highly	_	ADV	_	_	_	_	_	_
59	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
60	on	_	ADP	_	_	_	_	_	_
61	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
62	presence	_	NOUN	_	Number=Sing	_	_	_	_
63	of	_	ADP	_	_	_	_	_	_
64	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
65	properly	_	ADV	_	_	_	_	_	_
66	positioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
67	CCAAT	_	NOUN	_	Number=Sing	_	_	_	_
68	box	_	NOUN	_	Number=Sing	_	_	_	_
69	,	_	PUNCT	_	_	_	_	_	_
70	with	_	ADP	_	_	_	_	_	_
71	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
72	dependence	_	NOUN	_	Number=Sing	_	_	_	_
73	on	_	ADP	_	_	_	_	_	_
74	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
75	distal	_	ADJ	_	Degree=Pos	_	_	_	_
76	CCAAT	_	PROPN	_	Number=Sing	_	_	_	_
77	box	_	NOUN	_	Number=Sing	_	_	_	_
78	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
79	only	_	ADV	_	_	_	_	_	_
80	when	_	ADV	_	PronType=Int	_	_	_	_
81	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
82	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
83	CCAAT	_	NOUN	_	Number=Sing	_	_	_	_
84	box	_	NOUN	_	Number=Sing	_	_	_	_
85	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
86	deleted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
87	or	_	CCONJ	_	_	_	_	_	_
88	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
89	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
5	response	_	NOUN	_	Number=Sing	_	_	_	_
6	elements	_	NOUN	_	Number=Plur	_	_	_	_
7	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	at	_	ADP	_	_	_	_	_	_
9	ca.	_	NOUN	_	Number=Sing	_	_	_	_
10	bp	_	PROPN	_	Number=Sing	_	_	_	_
11	-850	_	PROPN	_	Number=Sing	_	_	_	_
12	upstream	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	Cp	_	NOUN	_	Number=Sing	_	_	_	_
15	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	not	_	PART	_	_	_	_	_	_
17	result	_	VERB	_	VerbForm=Inf	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	significant	_	ADJ	_	Degree=Pos	_	_	_	_
21	loss	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	general	_	ADJ	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	deletions	_	NOUN	_	Number=Plur	_	_	_	_
5	which	_	PRON	_	PronType=Rel	_	_	_	_
6	diminished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	Cp	_	NOUN	_	Number=Sing	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Wp	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	suppression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Wp	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
24	interference	_	NOUN	_	Number=Sing	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	Cp	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	identification	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	oriP	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	EBNA2	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	major	_	ADJ	_	Degree=Pos	_	_	_	_
14	positive	_	ADJ	_	Degree=Pos	_	_	_	_
15	cis	_	NOUN	_	Number=Sing	_	_	_	_
16	elements	_	NOUN	_	Number=Plur	_	_	_	_
17	involved	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	SCONJ	_	_	_	_	_	_
19	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	Cp	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	LCL	_	PROPN	_	Number=Sing	_	_	_	_
24	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	largely	_	ADV	_	_	_	_	_	_
31	autoregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	EBNA	_	PROPN	_	Number=Sing	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012741	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	AP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	insufficient	_	ADJ	_	Degree=Pos	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	requirement	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	CD28	_	PROPN	_	Number=Sing	_	_	_	_
23	up	_	ADP	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	regulation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	RE	_	ADP	_	_	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	AP	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	TCR	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	costimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	signals	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	superantigen	_	NOUN	_	Number=Sing	_	_	_	_
13	presented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	Raji	_	PROPN	_	Number=Sing	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	CD28	_	PROPN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	rCTLA4Ig	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	blocks	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	CD28	_	PROPN	_	Number=Sing	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	ligand	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	cultures	_	NOUN	_	Number=Plur	_	_	_	_
17	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	>	_	SYM	_	_	_	_	_	_
25	80	_	NUM	_	NumType=Card	_	_	_	_
26	%	_	SYM	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CTLA4Ig	_	PROPN	_	Number=Sing	_	_	_	_
4	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	significantly	_	ADV	_	_	_	_	_	_
7	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	either	_	CCONJ	_	_	_	_	_	_
12	NF	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	AP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	reporters	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	AP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	insufficient	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	RE	_	ADP	_	_	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	AP	_	NOUN	_	Number=Sing	_	_	_	_
8	reporter	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	CTLA4Ig	_	PROPN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	>	_	SYM	_	_	_	_	_	_
15	90	_	NUM	_	NumType=Card	_	_	_	_
16	%	_	SYM	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	requirement	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	CD28	_	PROPN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	due	_	ADP	_	_	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	RE	_	ADP	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	not	_	ADV	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	AP	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	sites	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	RE	_	ADP	_	_	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	AP	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	because	_	SCONJ	_	_	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
25	reporter	_	NOUN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	not	_	PART	_	_	_	_	_	_
28	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	addition	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	CTLA4Ig	_	PROPN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012745	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Anoxia	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	reoxygenation	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	respect	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	polymorphonuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
12	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Exposing	_	VERB	_	VerbForm=Ger	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
4	vein	_	NOUN	_	Number=Sing	_	_	_	_
5	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	anoxia	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	reoxygenation	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	A	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	R	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	results	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	increase	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	polymorphonuclear	_	ADJ	_	Degree=Pos	_	_	_	_
25	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	PMN	_	PROPN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	HUVECs	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	A/R	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	hyperadhesion	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	completely	_	ADV	_	_	_	_	_	_
8	prevented	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	previous	_	ADJ	_	Degree=Pos	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	24	_	NUM	_	NumType=Card	_	_	_	_
14	hours	_	NOUN	_	Number=Plur	_	_	_	_
15	earlier	_	ADV	_	Degree=Cmp	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	exposure	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	A	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	SYM	_	_	_	_	_	_
23	R	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	termed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	"	_	PUNCT	_	_	_	_	_	_
7	A	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	R	_	NOUN	_	Number=Sing	_	_	_	_
10	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_
12	"	_	PUNCT	_	_	_	_	_	_

1	Exposing	_	VERB	_	VerbForm=Ger	_	_	_	_
2	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	A/R	_	NOUN	_	Number=Sing	_	_	_	_
5	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	increase	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	HUVEC	_	PROPN	_	Number=Sing	_	_	_	_
19	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
20	within	_	ADP	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	hours	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Interfering	_	VERB	_	VerbForm=Ger	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	either	_	CCONJ	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
10	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	translocation	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	double	_	ADJ	_	Degree=Pos	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
19	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	sequence	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	development	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	A/R	_	NOUN	_	Number=Sing	_	_	_	_
31	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	ie	_	X	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	increase	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	A/R	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	PMN	_	PROPN	_	Number=Sing	_	_	_	_
42	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	HUVECs	_	PROPN	_	Number=Sing	_	_	_	_
45	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	same	_	ADJ	_	Degree=Pos	_	_	_	_
48	after	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
53	A/R	_	NOUN	_	Number=Sing	_	_	_	_
54	challenges	_	NOUN	_	Number=Plur	_	_	_	_
55	)	_	PUNCT	_	_	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	NO	_	DET	_	_	_	_	_	_
2	production	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	HUVECs	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	after	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
10	A/R	_	NOUN	_	Number=Sing	_	_	_	_
11	challenge	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	after	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
18	A/R	_	NOUN	_	Number=Sing	_	_	_	_
19	challenge	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NO	_	DET	_	_	_	_	_	_
4	synthase	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	NOS	_	X	_	_	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	during	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
11	A/R	_	NOUN	_	Number=Sing	_	_	_	_
12	challenge	_	NOUN	_	Number=Sing	_	_	_	_
13	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	development	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	A/R	_	NOUN	_	Number=Sing	_	_	_	_
18	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	respect	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	PMN	_	PROPN	_	Number=Sing	_	_	_	_
23	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	while	_	SCONJ	_	_	_	_	_	_
4	HUVECs	_	PROPN	_	Number=Sing	_	_	_	_
5	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	endothelial	_	NOUN	_	Number=Sing	_	_	_	_
7	NOS	_	PROPN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	no	_	DET	_	_	_	_	_	_
11	inducible	_	ADJ	_	Number=Sing	_	_	_	_
12	NOS	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	either	_	CCONJ	_	_	_	_	_	_
17	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	nontolerant	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	GTP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	cyclohydrolase	_	NOUN	_	Number=Sing	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
14	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	de	_	PROPN	_	Number=Sing	_	_	_	_
17	novo	_	PROPN	_	Number=Sing	_	_	_	_
18	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	important	_	ADJ	_	Degree=Pos	_	_	_	_
22	cofactor	_	NOUN	_	Number=Sing	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	NOS	_	NOUN	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	tetrahydrobiopterin	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	generation	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	NO	_	DET	_	_	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	A/R	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	generation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NO	_	INTJ	_	_	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	NO	_	DET	_	_	_	_	_	_
7	donor	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	effect	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	hyperadhesion	_	NOUN	_	Number=Sing	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	initial	_	ADJ	_	Degree=Pos	_	_	_	_
19	A/R	_	NOUN	_	Number=Sing	_	_	_	_
20	challenge	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	A/R	_	NOUN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
6	stress	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	naive	_	ADJ	_	Degree=Pos	_	_	_	_
9	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	ADV	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	A/R	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	tolerant	_	ADJ	_	Degree=Pos	_	_	_	_
17	HUVECs	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NOS	_	NOUN	_	Number=Sing	_	_	_	_
4	during	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	A/R	_	NOUN	_	Number=Sing	_	_	_	_
8	insult	_	NOUN	_	Number=Sing	_	_	_	_
9	results	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	generation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
16	stress	_	NOUN	_	Number=Sing	_	_	_	_
17	similar	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
20	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	after	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
24	A/R	_	NOUN	_	Number=Sing	_	_	_	_
25	challenge	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	findings	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	present	_	ADJ	_	Degree=Pos	_	_	_	_
9	study	_	NOUN	_	Number=Sing	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	consistent	_	ADJ	_	Degree=Pos	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	role	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	development	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	A/R	_	NOUN	_	Number=Sing	_	_	_	_
24	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	respect	_	NOUN	_	Number=Sing	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	PMN	_	PROPN	_	Number=Sing	_	_	_	_
30	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	perhaps	_	ADV	_	_	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
36	regulation	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	GTP	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	cyclohydrolase	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	NO	_	DET	_	_	_	_	_	_
4	production	_	NOUN	_	Number=Sing	_	_	_	_
5	during	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
8	A/R	_	NOUN	_	Number=Sing	_	_	_	_
9	insult	_	NOUN	_	Number=Sing	_	_	_	_
10	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	PMN	_	NOUN	_	Number=Sing	_	_	_	_
12	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
13	most	_	ADV	_	_	_	_	_	_
14	likely	_	ADJ	_	Degree=Pos	_	_	_	_
15	by	_	SCONJ	_	_	_	_	_	_
16	reducing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
19	oxidant	_	ADJ	_	Degree=Pos	_	_	_	_
20	stress	_	NOUN	_	Number=Sing	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	A/R	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012746	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Hypoxic	_	ADJ	_	Degree=Pos	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	8	_	NUM	_	NumType=Card	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	mediated	_	VERB	_	Degree=Pos	_	_	_	_
5	tissue	_	NOUN	_	Number=Sing	_	_	_	_
6	damage	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	important	_	ADJ	_	Degree=Pos	_	_	_	_
10	component	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	pathologic	_	ADJ	_	Degree=Pos	_	_	_	_
14	picture	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	ischemia	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	reperfusion	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
21	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	sought	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	PMNs	_	NOUN	_	Number=Plur	_	_	_	_
27	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	directed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	into	_	ADP	_	_	_	_	_	_
30	hypoxic	_	ADJ	_	Degree=Pos	_	_	_	_
31	tissue	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Incubation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	ECs	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	PO2	_	NOUN	_	Number=Sing	_	_	_	_
13	approximately	_	ADV	_	_	_	_	_	_
14	14	_	NUM	_	NumType=Card	_	_	_	_
15	-	_	SYM	_	_	_	_	_	_
16	18	_	NUM	_	NumType=Card	_	_	_	_
17	Torr	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	time	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
24	release	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	8	_	NUM	_	NumType=Card	_	_	_	_
29	antigen	_	NOUN	_	Number=Sing	_	_	_	_
30	into	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	conditioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	medium	_	NOUN	_	Number=Sing	_	_	_	_
34	;	_	PUNCT	_	_	_	_	_	_
35	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
36	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
37	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	by	_	ADP	_	_	_	_	_	_
39	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	chemotactic	_	ADJ	_	Degree=Pos	_	_	_	_
41	activity	_	NOUN	_	Number=Sing	_	_	_	_
42	for	_	ADP	_	_	_	_	_	_
43	PMNs	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	by	_	ADP	_	_	_	_	_	_
47	antibody	_	NOUN	_	Number=Sing	_	_	_	_
48	to	_	ADP	_	_	_	_	_	_
49	IL	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	8	_	NUM	_	NumType=Card	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Production	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	8	_	NUM	_	NumType=Card	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	hypoxic	_	ADJ	_	Degree=Pos	_	_	_	_
8	ECs	_	PROPN	_	Number=Sing	_	_	_	_
9	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	concomitantly	_	ADV	_	_	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	both	_	DET	_	_	_	_	_	_
13	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	8	_	NUM	_	NumType=Card	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
24	chain	_	NOUN	_	Number=Sing	_	_	_	_
25	reaction	_	NOUN	_	Number=Sing	_	_	_	_
26	analysis	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	IL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	8	_	NUM	_	NumType=Card	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	on	_	ADP	_	_	_	_	_	_
37	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
38	run	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	on	_	ADP	_	_	_	_	_	_
41	assays	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	hypoxic	_	PROPN	_	Degree=Pos	_	_	_	_
7	ECs	_	PROPN	_	Number=Sing	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	levels	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
16	chemotactic	_	ADJ	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	another	_	DET	_	_	_	_	_	_
22	member	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
26	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
29	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	8	_	NUM	_	NumType=Card	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	presence	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	extracts	_	NOUN	_	Number=Plur	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	hypoxic	_	ADJ	_	Degree=Pos	_	_	_	_
20	ECs	_	PROPN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kB	_	NOUN	_	Number=Sing	_	_	_	_
26	site	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	umbilical	_	ADJ	_	Degree=Pos	_	_	_	_
5	vein	_	NOUN	_	Number=Sing	_	_	_	_
6	segments	_	NOUN	_	Number=Plur	_	_	_	_
7	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
10	also	_	ADV	_	_	_	_	_	_
11	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	elaboration	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	8	_	NUM	_	NumType=Card	_	_	_	_
18	antigen	_	NOUN	_	Number=Sing	_	_	_	_
19	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	normoxic	_	ADJ	_	Degree=Pos	_	_	_	_
22	controls	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	mice	_	NOUN	_	Number=Plur	_	_	_	_
3	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	PO2	_	NOUN	_	Number=Sing	_	_	_	_
8	approximately	_	ADV	_	_	_	_	_	_
9	30	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	SYM	_	_	_	_	_	_
11	40	_	NUM	_	NumType=Card	_	_	_	_
12	Torr	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	there	_	PRON	_	_	_	_	_	_
16	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	pulmonary	_	ADJ	_	Degree=Pos	_	_	_	_
19	leukostasis	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	as	_	SCONJ	_	_	_	_	_	_
22	evidenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	myeloperoxidase	_	NOUN	_	Number=Sing	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	tissue	_	NOUN	_	Number=Sing	_	_	_	_
29	homogenates	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	parallel	_	ADJ	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	IP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	10	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	murine	_	NOUN	_	Number=Sing	_	_	_	_
15	homologue	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
19	family	_	NOUN	_	Number=Sing	_	_	_	_
20	related	_	ADJ	_	Degree=Pos	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	8	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	hypoxic	_	ADJ	_	Degree=Pos	_	_	_	_
30	lung	_	NOUN	_	Number=Sing	_	_	_	_
31	tissue	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	hypoxia	_	NOUN	_	Number=Sing	_	_	_	_
9	constitutes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	leukocyte	_	ADJ	_	Number=Sing	_	_	_	_
14	chemotaxis	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	tissue	_	NOUN	_	Number=Sing	_	_	_	_
17	leukostasis	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012747	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Coactivation	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	OCA	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	:	_	PUNCT	_	_	_	_	_	_
7	definition	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	critical	_	ADJ	_	Degree=Pos	_	_	_	_
10	regions	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	synergism	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	general	_	ADJ	_	Degree=Pos	_	_	_	_
15	cofactors	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Molecular	_	ADJ	_	Degree=Pos	_	_	_	_
2	dissection	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	B-cell	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
10	OCA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
16	regions	_	NOUN	_	Number=Plur	_	_	_	_
17	important	_	ADJ	_	Degree=Pos	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	respectively	_	ADV	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	recruitment	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
25	promoters	_	NOUN	_	Number=Plur	_	_	_	_
26	through	_	ADP	_	_	_	_	_	_
27	interaction	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	octamer	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	bound	_	ADJ	_	Degree=Pos	_	_	_	_
32	Oct	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
38	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
39	function	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	general	_	ADJ	_	Degree=Pos	_	_	_	_
5	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
6	requirements	_	NOUN	_	Number=Plur	_	_	_	_
7	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	selective	_	ADJ	_	Degree=Pos	_	_	_	_
10	removal	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	PC4	_	NOUN	_	Number=Sing	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	essential	_	ADJ	_	Degree=Pos	_	_	_	_
16	USA	_	PROPN	_	Number=Sing	_	_	_	_
17	fraction	_	NOUN	_	Number=Sing	_	_	_	_
18	severely	_	ADV	_	_	_	_	_	_
19	impairs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	Oct	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	OCA	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	function	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	free	_	ADJ	_	Degree=Pos	_	_	_	_
33	system	_	NOUN	_	Number=Sing	_	_	_	_
34	reconstituted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	partially	_	ADV	_	_	_	_	_	_
37	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	factors	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Full	_	ADJ	_	Degree=Pos	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	can	_	AUX	_	VerbForm=Fin	_	_	_	_
4	be	_	AUX	_	VerbForm=Inf	_	_	_	_
5	restored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	action	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	recombinant	_	ADJ	_	Number=Sing	_	_	_	_
12	PC4	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	PC4	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	depleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	USA	_	PROPN	_	Number=Sing	_	_	_	_
19	fraction	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	thus	_	ADV	_	_	_	_	_	_
22	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	joint	_	ADJ	_	Degree=Pos	_	_	_	_
25	requirement	_	NOUN	_	Number=Sing	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	PC4	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	another	_	DET	_	_	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	USA	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	component	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	s	_	X	_	_	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	for	_	ADP	_	_	_	_	_	_
39	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
40	function	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	Oct	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1/OCA	_	NOUN	_	Number=Sing	_	_	_	_
45	-B	_	NOUN	_	Number=Sing	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	reconstituted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	system	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	Indeed	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	USA	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	PC2	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	act	_	VERB	_	VerbForm=Inf	_	_	_	_
11	synergistically	_	ADV	_	_	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	PC4	_	PROPN	_	Number=Sing	_	_	_	_
14	in	_	SCONJ	_	_	_	_	_	_
15	reproducing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	function	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	intact	_	VERB	_	VerbForm=Ger	_	_	_	_
20	USA	_	PROPN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	assay	_	NOUN	_	Number=Sing	_	_	_	_
24	system	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	requirement	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	PC4	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	reconstituted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	system	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	OCA	_	PROPN	_	Number=Sing	_	_	_	_
13	-B	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
18	directly	_	ADV	_	_	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	PC4	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Surprisingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	however	_	ADV	_	_	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	removal	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	PC4	_	NOUN	_	Number=Sing	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	unfractionated	_	ADJ	_	Degree=Pos	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	extract	_	NOUN	_	Number=Sing	_	_	_	_
13	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	no	_	DET	_	_	_	_	_	_
15	detrimental	_	ADJ	_	Degree=Pos	_	_	_	_
16	effect	_	NOUN	_	Number=Sing	_	_	_	_
17	on	_	ADP	_	_	_	_	_	_
18	OCA	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	B/Oct	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	lead	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	general	_	ADJ	_	Degree=Pos	_	_	_	_
7	model	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	synergistic	_	ADJ	_	Degree=Pos	_	_	_	_
11	function	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	domains	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	Oct	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	OCA	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	B	_	PROPN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	action	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
32	USA	_	PROPN	_	Number=Sing	_	_	_	_
33	components	_	NOUN	_	Number=Plur	_	_	_	_
34	)	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	further	_	ADV	_	_	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	functional	_	ADJ	_	Degree=Pos	_	_	_	_
42	redundancy	_	NOUN	_	Number=Sing	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	general	_	ADJ	_	Degree=Pos	_	_	_	_
45	coactivators	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012752	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	c	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	jun	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	during	_	ADP	_	_	_	_	_	_
8	induction	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
14	acid	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	work	_	NOUN	_	Number=Sing	_	_	_	_
4	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	examined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	okadaic	_	PROPN	_	Number=Sing	_	_	_	_
10	acid	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	type	_	NOUN	_	Number=Sing	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	2A	_	NUM	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	regulation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	c	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	jun	_	NOUN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	during	_	ADP	_	_	_	_	_	_
31	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
32	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	U	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	SYM	_	_	_	_	_	_
36	937	_	NUM	_	NumType=Card	_	_	_	_
37	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
6	acid	_	NOUN	_	Number=Sing	_	_	_	_
7	treatment	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	differentiated	_	ADJ	_	Degree=Pos	_	_	_	_
15	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
16	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
17	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	a	_	X	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	growth	_	NOUN	_	Number=Sing	_	_	_	_
24	arrest	_	NOUN	_	Number=Sing	_	_	_	_
25	;	_	PUNCT	_	_	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	b	_	X	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	increases	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	Mac	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	surface	_	NOUN	_	Number=Sing	_	_	_	_
36	antigen	_	NOUN	_	Number=Sing	_	_	_	_
37	expression	_	NOUN	_	Number=Sing	_	_	_	_
38	;	_	PUNCT	_	_	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	c	_	NOUN	_	_	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	down	_	ADP	_	_	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	regulation	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
47	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
48	;	_	PUNCT	_	_	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	(	_	PUNCT	_	_	_	_	_	_
51	d	_	NOUN	_	Number=Sing	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	induction	_	NOUN	_	Number=Sing	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	tumor	_	NOUN	_	Number=Sing	_	_	_	_
56	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
57	factor	_	NOUN	_	Number=Sing	_	_	_	_
58	gene	_	NOUN	_	Number=Sing	_	_	_	_
59	expression	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
5	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	transient	_	ADJ	_	Degree=Pos	_	_	_	_
10	increases	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	c	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	jun	_	NOUN	_	Number=Sing	_	_	_	_
15	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
16	levels	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
21	at	_	ADP	_	_	_	_	_	_
22	6	_	NUM	_	NumType=Card	_	_	_	_
23	h	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	c	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	fos	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Run	_	VERB	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	on	_	ADP	_	_	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	c	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	jun	_	NOUN	_	Number=Sing	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	U	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	937	_	NUM	_	NumType=Card	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	rate	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	approximately	_	ADV	_	_	_	_	_	_
25	40	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	fold	_	NOUN	_	Number=Sing	_	_	_	_
28	following	_	VERB	_	VerbForm=Ger	_	_	_	_
29	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
30	acid	_	VERB	_	Degree=Pos	_	_	_	_
31	exposure	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	c	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	jun	_	NOUN	_	Number=Sing	_	_	_	_
4	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
5	levels	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	superinduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	both	_	CCONJ	_	_	_	_	_	_
13	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
14	acid	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	whereas	_	SCONJ	_	_	_	_	_	_
19	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
23	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	little	_	ADJ	_	Degree=Pos	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	if	_	SCONJ	_	_	_	_	_	_
27	any	_	DET	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	effect	_	NOUN	_	Number=Sing	_	_	_	_
30	on	_	ADP	_	_	_	_	_	_
31	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
32	acid	_	ADJ	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	c	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	jun	_	NOUN	_	Number=Sing	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	half	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	life	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	c	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	jun	_	NOUN	_	Number=Sing	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	similar	_	ADJ	_	Degree=Pos	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	45	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	50	_	NUM	_	NumType=Card	_	_	_	_
16	min	_	NOUN	_	Number=Plur	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	untreated	_	ADJ	_	Degree=Pos	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
23	acid	_	ADJ	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	treatment	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	both	_	DET	_	_	_	_	_	_
7	okadaic	_	ADJ	_	Degree=Pos	_	_	_	_
8	acid	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	stabilization	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	t	_	NOUN	_	Number=Sing	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	=	_	SYM	_	_	_	_	_	_
21	90	_	NUM	_	NumType=Card	_	_	_	_
22	min	_	NOUN	_	Number=Plur	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	c	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	jun	_	NOUN	_	Number=Sing	_	_	_	_
28	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	findings	_	NOUN	_	Number=Plur	_	_	_	_
6	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	c	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	jun	_	NOUN	_	Number=Sing	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	okadaic	_	ADJ	_	Number=Sing	_	_	_	_
17	acid	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	primarily	_	ADV	_	_	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
24	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	previous	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	c-jun	_	NOUN	_	Degree=Pos	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	autoinduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	Jun	_	PROPN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	AP	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
20	also	_	ADV	_	_	_	_	_	_
21	studied	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	c	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	jun	_	NOUN	_	Number=Sing	_	_	_	_
27	promoter	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	positions	_	NOUN	_	Number=Plur	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	132/+170	_	NUM	_	NumType=Card	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	reporter	_	NOUN	_	Number=Sing	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	constructs	_	VERB	_	Number=Plur	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	without	_	ADP	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	AP	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	element	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	0030012757	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Occurrence	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	silencer	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2	_	NUM	_	NumType=Card	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	naive	_	ADJ	_	Degree=Pos	_	_	_	_
13	but	_	CCONJ	_	_	_	_	_	_
14	not	_	ADV	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	memory	_	NOUN	_	Number=Sing	_	_	_	_
17	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	helper	_	VERB	_	Number=Sing	_	_	_	_
20	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	immune	_	NOUN	_	Number=Sing	_	_	_	_
4	system	_	NOUN	_	Number=Sing	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	naive	_	ADJ	_	Degree=Pos	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	antigen	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	key	_	ADJ	_	Degree=Pos	_	_	_	_
18	step	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	shaping	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	specificity	_	NOUN	_	Number=Sing	_	_	_	_
28	repertoire	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	maintenance	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	self	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	analysis	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	_	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	shows	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	that	_	DET	_	_	_	_	_	_
21	naive	_	ADJ	_	Degree=Pos	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	helper	_	NOUN	_	Number=Sing	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	cord	_	NOUN	_	Number=Sing	_	_	_	_
28	blood	_	NOUN	_	Number=Sing	_	_	_	_
29	CD4	_	NOUN	_	Number=Sing	_	_	_	_
30	+	_	SYM	_	_	_	_	_	_

1	T	_	X	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	adult	_	NOUN	_	Number=Sing	_	_	_	_
5	CD4	_	NOUN	_	Number=Sing	_	_	_	_
6	+	_	SYM	_	_	_	_	_	_
7	CD45RO	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	T	_	X	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
20	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
21	both	_	CCONJ	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	silencer	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	activator	_	NOUN	_	Number=Sing	_	_	_	_
27	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	purine	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	rich	_	ADJ	_	Degree=Pos	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	elements	_	NOUN	_	Number=Plur	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	AT	_	ADP	_	_	_	_	_	_
42	binding	_	NOUN	_	Number=Sing	_	_	_	_
43	sites	_	NOUN	_	Number=Plur	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	memory	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	either	_	CCONJ	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	vitro	_	NOUN	_	Number=Sing	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	helper	_	NOUN	_	Number=Sing	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	reverting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	resting	_	NOUN	_	Number=Sing	_	_	_	_
18	state	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	CD4	_	NOUN	_	Number=Sing	_	_	_	_
22	+	_	SYM	_	_	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	memory	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	clones	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	CD4+CD45RO	_	NOUN	_	Number=Sing	_	_	_	_
31	+	_	SYM	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	ex	_	NOUN	_	Number=Sing	_	_	_	_
5	vivo	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	no	_	ADV	_	_	_	_	_	_
8	longer	_	ADV	_	Degree=Cmp	_	_	_	_
9	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	silencer	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	solely	_	ADV	_	_	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transition	_	NOUN	_	Number=Sing	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	inactive	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	active	_	ADJ	_	Degree=Pos	_	_	_	_
18	functional	_	ADJ	_	Degree=Pos	_	_	_	_
19	state	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	positive	_	ADJ	_	Degree=Pos	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	binding	_	VERB	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	elements	_	NOUN	_	Number=Plur	_	_	_	_
30	as	_	ADV	_	_	_	_	_	_
31	well	_	ADV	_	Degree=Pos	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	cytoplasmic	_	ADJ	_	Number=Sing	_	_	_	_
35	or	_	CCONJ	_	_	_	_	_	_
36	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
37	location	_	NOUN	_	Number=Sing	_	_	_	_
38	:	_	PUNCT	_	_	_	_	_	_
39	in	_	SCONJ	_	_	_	_	_	_
40	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
41	memory	_	NOUN	_	Number=Sing	_	_	_	_
42	T	_	PROPN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	activator	_	NOUN	_	Number=Sing	_	_	_	_
46	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
47	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
53	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	whereas	_	SCONJ	_	_	_	_	_	_
56	in	_	ADP	_	_	_	_	_	_
57	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
58	cells	_	NOUN	_	Number=Plur	_	_	_	_
59	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
60	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
61	functional	_	ADJ	_	Degree=Pos	_	_	_	_
62	in	_	SCONJ	_	_	_	_	_	_
63	promoting	_	VERB	_	VerbForm=Ger	_	_	_	_
64	transcription	_	NOUN	_	Number=Sing	_	_	_	_
65	and	_	CCONJ	_	_	_	_	_	_
66	now	_	ADV	_	_	_	_	_	_
67	resides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
68	in	_	ADP	_	_	_	_	_	_
69	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
70	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
71	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	coding	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	main	_	ADJ	_	Degree=Pos	_	_	_	_
12	T	_	NOUN	_	NumType=Card	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	growth	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	changes	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	irreversibly	_	ADV	_	_	_	_	_	_
18	after	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
21	encounter	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	T	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	antigen	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	most	_	ADV	_	_	_	_	_	_
4	likely	_	ADJ	_	Degree=Pos	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	presence	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	silencer	_	NOUN	_	Number=Sing	_	_	_	_
11	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	more	_	ADV	_	_	_	_	_	_
15	stringent	_	ADJ	_	Degree=Pos	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	requirements	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	naive	_	ADJ	_	Degree=Pos	_	_	_	_
20	CD4	_	NOUN	_	Number=Sing	_	_	_	_
21	+	_	SYM	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012759	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Permanent	_	ADJ	_	Degree=Pos	_	_	_	_
2	occupancy	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	PROPN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	needed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
20	viral	_	ADJ	_	Degree=Pos	_	_	_	_
21	replication	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	work	_	NOUN	_	Number=Sing	_	_	_	_
3	aimed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	ascertain	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	role	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
12	elements	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	HIV	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	_	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
26	not	_	ADV	_	_	_	_	_	_
27	only	_	ADV	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	early	_	ADJ	_	Degree=Pos	_	_	_	_
30	initiation	_	NOUN	_	Number=Sing	_	_	_	_
31	but	_	CCONJ	_	_	_	_	_	_
32	also	_	ADV	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	long	_	ADJ	_	Degree=Pos	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	term	_	NOUN	_	Number=Sing	_	_	_	_
37	maintenance	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
40	transcription	_	NOUN	_	Number=Sing	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	cells	_	NOUN	_	Number=Plur	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
46	lineage	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	purpose	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	three	_	NUM	_	NumType=Card	_	_	_	_
8	main	_	ADJ	_	Degree=Pos	_	_	_	_
9	approaches	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	abruptly	_	ADV	_	_	_	_	_	_
6	terminate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	tumor	_	NOUN	_	Number=Sing	_	_	_	_
8	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
19	sequences	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	U1	_	PROPN	_	Number=Sing	_	_	_	_
22	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	using	_	VERB	_	VerbForm=Ger	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	short	_	ADJ	_	Degree=Pos	_	_	_	_
28	pulse	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
31	tumor	_	NOUN	_	Number=Sing	_	_	_	_
32	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
33	factor	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
5	decrease	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	NF	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	DNA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
17	long	_	ADJ	_	Degree=Pos	_	_	_	_
18	terminal	_	NOUN	_	Number=Sing	_	_	_	_
19	repeat	_	NOUN	_	Number=Sing	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	second	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	permanent	_	ADJ	_	Degree=Pos	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
11	translocation	_	NOUN	_	Number=Sing	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	HIV	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	replication	_	NOUN	_	Number=Sing	_	_	_	_
18	itself	_	PRON	_	Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	chronically	_	ADV	_	_	_	_	_	_
21	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	U937	_	NUM	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	using	_	VERB	_	VerbForm=Ger	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	proteasome	_	NOUN	_	Degree=Pos	_	_	_	_
29	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	Z	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	LLL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	H	_	NOUN	_	_	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADV	_	_	_	_	_	_
2	early	_	ADV	_	Degree=Pos	_	_	_	_
3	as	_	ADP	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	h	_	NOUN	_	Number=Sing	_	_	_	_
6	after	_	ADP	_	_	_	_	_	_
7	addition	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	culture	_	NOUN	_	Number=Sing	_	_	_	_
14	medium	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	there	_	PRON	_	_	_	_	_	_
17	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	both	_	DET	_	_	_	_	_	_
22	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	HIV	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	genome	_	NOUN	_	Number=Sing	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	third	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	approach	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	monitor	_	VERB	_	VerbForm=Inf	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	replication	_	NOUN	_	Number=Sing	_	_	_	_
9	competence	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	U937	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	infectious	_	ADJ	_	Degree=Pos	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	provirus	_	NOUN	_	Number=Sing	_	_	_	_
20	carrying	_	VERB	_	VerbForm=Ger	_	_	_	_
21	point	_	NOUN	_	Number=Sing	_	_	_	_
22	mutations	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
28	elements	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	both	_	DET	_	_	_	_	_	_
31	long	_	ADJ	_	Degree=Pos	_	_	_	_
32	terminal	_	NOUN	_	Number=Sing	_	_	_	_
33	repeats	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
4	wild	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	type	_	NOUN	_	Number=Sing	_	_	_	_
7	counterpart	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
10	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	provirus	_	NOUN	_	Number=Sing	_	_	_	_
12	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	profoundly	_	ADV	_	_	_	_	_	_
15	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	Z	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	LLL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	H-insensitive	_	ADJ	_	Degree=Pos	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	replicative	_	ADJ	_	Degree=Pos	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	U937	_	PROPN	_	Number=Sing	_	_	_	_
28	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	occupancy	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	viral	_	ADJ	_	Degree=Pos	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	p50	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	p65	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	ongoing	_	ADJ	_	Degree=Pos	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	integrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	HIV	_	NOUN	_	Number=Sing	_	_	_	_
30	provirus	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	even	_	ADV	_	_	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	chronically	_	ADV	_	_	_	_	_	_
38	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	permanently	_	ADV	_	_	_	_	_	_
41	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
42	functional	_	ADJ	_	Degree=Pos	_	_	_	_
43	HIV	_	NOUN	_	Number=Sing	_	_	_	_
44	Tat	_	NOUN	_	Number=Sing	_	_	_	_
45	protein	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	ability	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	HIV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	replication	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	intense	_	ADJ	_	Degree=Pos	_	_	_	_
20	self	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	perpetuated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	viral	_	ADJ	_	Degree=Pos	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
31	lineage	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012763	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Efficient	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	replication	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	simian	_	ADJ	_	Degree=Pos	_	_	_	_
7	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	absence	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	elements	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Ten	_	NUM	_	NumType=Card	_	_	_	_
2	mutants	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	simian	_	ADJ	_	Degree=Pos	_	_	_	_
6	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	SIV	_	PROPN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	SIVmac239	_	NUM	_	NumType=Card	_	_	_	_
12	bearing	_	VERB	_	Number=Sing	_	_	_	_
13	deletions	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	delta	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	substitutions	_	NOUN	_	Number=Plur	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	subst	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
31	binding	_	NOUN	_	Number=Sing	_	_	_	_
32	elements	_	NOUN	_	Number=Plur	_	_	_	_
33	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	created	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	replicative	_	ADJ	_	Degree=Pos	_	_	_	_
39	capacities	_	NOUN	_	Number=Plur	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	mutants	_	NOUN	_	Number=Plur	_	_	_	_
43	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
44	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	mutants	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	including	_	VERB	_	VerbForm=Ger	_	_	_	_
5	one	_	NUM	_	NumType=Card	_	_	_	_
6	extensively	_	ADV	_	_	_	_	_	_
7	mutagenized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	strain	_	NOUN	_	Number=Sing	_	_	_	_
9	entirely	_	ADV	_	_	_	_	_	_
10	missing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	four	_	NUM	_	NumType=Card	_	_	_	_
17	Spl	_	NOUN	_	Number=Sing	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	elements	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	replicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	wild	_	ADJ	_	Degree=Pos	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	type	_	NOUN	_	Number=Sing	_	_	_	_
26	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	wild	_	ADJ	_	Degree=Pos	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	type	_	NOUN	_	Number=Sing	_	_	_	_
33	level	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
36	blood	_	NOUN	_	Number=Sing	_	_	_	_
37	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	cultures	_	NOUN	_	Number=Plur	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	50	_	NUM	_	NumType=Card	_	_	_	_
42	to	_	ADP	_	_	_	_	_	_
43	100	_	NUM	_	NumType=Card	_	_	_	_
44	%	_	SYM	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	experiments	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	group	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	mutants	_	NOUN	_	Number=Plur	_	_	_	_
5	replicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	very	_	ADV	_	_	_	_	_	_
7	similarly	_	ADV	_	_	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	SIVmac239	_	PROPN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	yield	_	VERB	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	CEMxl74	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	2xNFKappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	>	_	PUNCT	_	_	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	=	_	PUNCT	_	_	_	_	_	_
22	SlVmac239	_	NUM	_	Number=Sing	_	_	_	_
23	approximately	_	ADV	_	_	_	_	_	_
24	deltaNFkappaB	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
25	approximately	_	ADV	_	_	_	_	_	_
26	deltaSpl234	_	NUM	_	NumType=Card	_	_	_	_
27	approximately	_	ADV	_	_	_	_	_	_
28	substNFkappaB	_	VERB	_	NumType=Card	_	_	_	_
29	approximately	_	ADV	_	_	_	_	_	_
30	substSpl2	_	VERB	_	NumType=Card	_	_	_	_
31	approximately	_	ADV	_	_	_	_	_	_
32	substSp23	_	NUM	_	NumType=Card	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	while	_	SCONJ	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
38	group	_	NOUN	_	Number=Sing	_	_	_	_
39	replicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
42	or	_	CCONJ	_	_	_	_	_	_
43	slightly	_	ADV	_	_	_	_	_	_
44	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
45	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	CEMxl74	_	PROPN	_	Number=Sing	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	SIVmac239	_	PROPN	_	Number=Sing	_	_	_	_
51	>	_	PUNCT	_	_	_	_	_	_
52	substSp34	_	X	_	Number=Sing	_	_	_	_
53	>	_	PUNCT	_	_	_	_	_	_
54	deltaNFkappaBdeltaSpl234	_	NUM	_	NumType=Card	_	_	_	_
55	approximately	_	ADV	_	_	_	_	_	_
56	deltaNFkappaBdeltaSp1	_	X	_	NumType=Card	_	_	_	_
57	>	_	PUNCT	_	_	_	_	_	_
58	substSpl234	_	NUM	_	NumType=Card	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Reversions	_	NOUN	_	Number=Plur	_	_	_	_
2	or	_	CCONJ	_	_	_	_	_	_
3	additional	_	ADJ	_	Degree=Pos	_	_	_	_
4	mutations	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	U3	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	R	_	PROPN	_	Number=Sing	_	_	_	_
13	regions	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	CEMxl74	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	SIVmac239	_	NUM	_	Number=Sing	_	_	_	_
24	mutants	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	when	_	ADV	_	PronType=Int	_	_	_	_
6	mutants	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	SIVmacMER	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	competent	_	ADJ	_	Degree=Pos	_	_	_	_
14	derivative	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	SIVmac239	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	tested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
22	blood	_	NOUN	_	Number=Sing	_	_	_	_
23	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	CEMx174	_	ADJ	_	Degree=Pos	_	_	_	_
27	cultures	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	growth	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	most	_	ADV	_	_	_	_	_	_
7	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	viruses	_	NOUN	_	Number=Plur	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	primary	_	ADJ	_	Degree=Pos	_	_	_	_
13	rhesus	_	NOUN	_	Number=Sing	_	_	_	_
14	monkey	_	NOUN	_	Number=Sing	_	_	_	_
15	alveolar	_	NOUN	_	Number=Sing	_	_	_	_
16	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	SIVmacMER	_	PROPN	_	Number=Sing	_	_	_	_
19	approximately	_	ADV	_	_	_	_	_	_
20	2xNFkappaB	_	NUM	_	NumType=Card	_	_	_	_
21	approximately	_	ADV	_	_	_	_	_	_
22	substNFkappaB	_	NUM	_	NumType=Card	_	_	_	_
23	>	_	PUNCT	_	_	_	_	_	_
24	deltaNFkappaB	_	X	_	Number=Sing	_	_	_	_
25	>	_	PUNCT	_	_	_	_	_	_
26	deltaNFkappaBdeltaSpl234	_	NUM	_	NumType=Card	_	_	_	_
27	approximately	_	ADV	_	_	_	_	_	_
28	deltaNFkappaBdeltaSpl	_	X	_	_	_	_	_	_
29	>	_	PUNCT	_	_	_	_	_	_
30	deltaSpl234	_	NUM	_	NumType=Card	_	_	_	_
31	approximately	_	ADV	_	_	_	_	_	_
32	substSpl2	_	VERB	_	NumType=Card	_	_	_	_
33	>	_	PUNCT	_	_	_	_	_	_
34	substSp23	_	VERB	_	_	_	_	_	_
35	approximately	_	ADV	_	_	_	_	_	_
36	substSp34	_	VERB	_	NumType=Card	_	_	_	_
37	approximately	_	ADV	_	_	_	_	_	_
38	substSpl234	_	NUM	_	NumType=Card	_	_	_	_
39	>	_	PUNCT	_	_	_	_	_	_
40	or	_	CCONJ	_	_	_	_	_	_
41	=	_	PUNCT	_	_	_	_	_	_
42	SIVmac239	_	NUM	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	changes	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	sites	_	NOUN	_	Number=Plur	_	_	_	_
9	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	most	_	ADV	_	_	_	_	_	_
12	dramatic	_	ADJ	_	Degree=Pos	_	_	_	_
13	effects	_	NOUN	_	Number=Plur	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	SIVmac	_	ADJ	_	Number=Sing	_	_	_	_
16	replication	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	primary	_	ADJ	_	Degree=Pos	_	_	_	_
19	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
20	cultures	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	long	_	ADJ	_	Degree=Pos	_	_	_	_
4	terminal	_	NOUN	_	Number=Sing	_	_	_	_
5	repeat	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	alkaline	_	ADJ	_	Number=Sing	_	_	_	_
10	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	transient	_	ADJ	_	Number=Sing	_	_	_	_
14	assays	_	NOUN	_	Number=Plur	_	_	_	_
15	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	unlike	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
21	virus	_	NOUN	_	Number=Sing	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	SIV	_	PROPN	_	Number=Sing	_	_	_	_
27	long	_	ADJ	_	Degree=Pos	_	_	_	_
28	terminal	_	NOUN	_	Number=Sing	_	_	_	_
29	repeat	_	NOUN	_	Number=Sing	_	_	_	_
30	possesses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
33	region	_	NOUN	_	Number=Sing	_	_	_	_
34	just	_	ADV	_	_	_	_	_	_
35	upstream	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	NF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
41	element	_	NOUN	_	Number=Sing	_	_	_	_
42	which	_	PRON	_	PronType=Rel	_	_	_	_
43	maintains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
44	significant	_	ADJ	_	Degree=Pos	_	_	_	_
45	levels	_	NOUN	_	Number=Plur	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	basal	_	ADJ	_	Degree=Pos	_	_	_	_
48	transcription	_	NOUN	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	absence	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	NF	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
58	sites	_	NOUN	_	Number=Plur	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	region	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	Tat	_	PROPN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	SIV	_	PROPN	_	Number=Sing	_	_	_	_
6	TATA	_	PROPN	_	Number=Sing	_	_	_	_
7	box	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	stronger	_	ADJ	_	Degree=Cmp	_	_	_	_
13	than	_	ADP	_	_	_	_	_	_
14	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	type	_	NOUN	_	Number=Sing	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	surprisingly	_	ADV	_	_	_	_	_	_
5	high	_	ADJ	_	Degree=Pos	_	_	_	_
6	replicative	_	ADJ	_	Degree=Pos	_	_	_	_
7	capacity	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	site	_	NOUN	_	Number=Sing	_	_	_	_
16	mutants	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	SIVmac	_	PROPN	_	Number=Sing	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	due	_	ADP	_	_	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	unique	_	ADJ	_	Degree=Pos	_	_	_	_
23	features	_	NOUN	_	Number=Plur	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
27	/	_	PUNCT	_	_	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	region	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012767	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	chain	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor.kappa	_	NOUN	_	Number=Sing	_	_	_	_

1	B	_	ADJ	_	Number=Sing	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	C	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Autocrine	_	ADJ	_	Degree=Pos	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	tumor	_	NOUN	_	Number=Sing	_	_	_	_
5	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	alpha	_	PROPN	_	Number=Sing	_	_	_	_
9	chain	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2R	_	NUM	_	Number=Sing	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	kinase	_	NOUN	_	Number=Sing	_	_	_	_
27	C	_	PROPN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	PKC	_	PROPN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	in	_	SCONJ	_	_	_	_	_	_
32	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
33	T	_	NOUN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
38	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	resting	_	VERB	_	Number=Sing	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
9	esters	_	NOUN	_	Number=Plur	_	_	_	_
10	strongly	_	ADV	_	_	_	_	_	_
11	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2R	_	NOUN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF.	_	PROPN	_	Number=Sing	_	_	_	_
24	kappa	_	PROPN	_	Number=Sing	_	_	_	_
25	B	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	due	_	ADP	_	_	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	translocation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	p65	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	c-Rel	_	PROPN	_	Number=Sing	_	_	_	_
12	NF.	_	PROPN	_	Number=Sing	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
18	stores	_	NOUN	_	Number=Plur	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	where	_	ADV	_	PronType=Rel	_	_	_	_
24	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
25	bound	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	kappa	_	PROPN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	sequence	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	2R	_	NOUN	_	Number=Sing	_	_	_	_
35	alpha	_	NOUN	_	Number=Sing	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	either	_	ADV	_	_	_	_	_	_
38	as	_	ADP	_	_	_	_	_	_
39	p50.p65	_	NUM	_	NumType=Card	_	_	_	_
40	or	_	CCONJ	_	_	_	_	_	_
41	as	_	ADP	_	_	_	_	_	_
42	p50.c	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	Rel	_	NOUN	_	Number=Sing	_	_	_	_
45	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	all	_	DET	_	_	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	events	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	largely	_	ADV	_	_	_	_	_	_
9	indirect	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	endogenously	_	ADV	_	_	_	_	_	_
14	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	tumor	_	NOUN	_	Number=Sing	_	_	_	_
16	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	TNF	_	PROPN	_	Number=Sing	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	as	_	SCONJ	_	_	_	_	_	_
25	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	strongly	_	ADV	_	_	_	_	_	_
28	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	neutralizing	_	VERB	_	VerbForm=Ger	_	_	_	_
32	anti-TNF	_	ADJ	_	Number=Sing	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
35	antibody	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
4	A	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	production	_	NOUN	_	Number=Sing	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	PKC	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	strongly	_	ADV	_	_	_	_	_	_
16	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2R	_	PROPN	_	Number=Sing	_	_	_	_
20	alpha	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	NF.	_	PROPN	_	Number=Sing	_	_	_	_
23	kappa	_	PROPN	_	Number=Sing	_	_	_	_
24	B	_	PROPN	_	Number=Sing	_	_	_	_
25	activation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	either	_	CCONJ	_	_	_	_	_	_
5	TNF	_	PROPN	_	Number=Sing	_	_	_	_
6	alpha	_	PROPN	_	Number=Sing	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	partially	_	ADV	_	_	_	_	_	_
12	recovered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
14	A	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2R	_	NOUN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	but	_	CCONJ	_	_	_	_	_	_
24	only	_	ADV	_	_	_	_	_	_
25	TNF	_	PROPN	_	Number=Sing	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	completely	_	ADV	_	_	_	_	_	_
28	recovered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	NF.	_	PROPN	_	Number=Sing	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	in	_	SCONJ	_	_	_	_	_	_
7	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
8	T	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	PKC	_	PROPN	_	Number=Sing	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	only	_	ADV	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	triggering	_	VERB	_	VerbForm=Ger	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	whereas	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	endogenously	_	ADV	_	_	_	_	_	_
22	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	TNF	_	PROPN	_	Number=Sing	_	_	_	_
24	alpha	_	PROPN	_	Number=Sing	_	_	_	_
25	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	essential	_	ADJ	_	Degree=Pos	_	_	_	_
28	role	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	quantitative	_	ADJ	_	Degree=Pos	_	_	_	_
32	control	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2R	_	PROPN	_	Number=Sing	_	_	_	_
40	alpha	_	PROPN	_	Number=Sing	_	_	_	_
41	chain	_	NOUN	_	Number=Sing	_	_	_	_
42	or	_	CCONJ	_	_	_	_	_	_
43	NF.	_	PROPN	_	Number=Sing	_	_	_	_
44	kappa	_	PROPN	_	Number=Sing	_	_	_	_
45	B	_	PROPN	_	Number=Sing	_	_	_	_
46	activation	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012769	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Octamer	_	NOUN	_	Number=Sing	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
6	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	murine	_	NOUN	_	Number=Sing	_	_	_	_
11	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	spi	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	spi	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	member	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	Ets	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	family	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	predominantly	_	ADV	_	_	_	_	_	_
19	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	B	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	many	_	ADJ	_	Degree=Pos	_	_	_	_
28	B	_	ADJ	_	Degree=Pos	_	_	_	_
29	cell	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	critical	_	ADJ	_	Degree=Pos	_	_	_	_
37	for	_	ADP	_	_	_	_	_	_
38	development	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	both	_	DET	_	_	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
43	lineages	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	previous	_	ADJ	_	Degree=Pos	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	Chen	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	H.M.	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	Ray	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	Gallet	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	D.	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	Zhang	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	P.	_	PROPN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	Hetherington	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	C.J.	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	Gonzalez	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	D.A.	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	Zhang	_	PROPN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	D.	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	E.	_	PROPN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	Moreau	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	Gachelin	_	PROPN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	F.	_	PROPN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	Tenen	_	PROPN	_	Number=Sing	_	_	_	_
41	,	_	PUNCT	_	_	_	_	_	_
42	D.G.	_	PROPN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	1995	_	NUM	_	NumType=Card	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_

1	Oncogene	_	PROPN	_	Number=Sing	_	_	_	_
2	11	_	NUM	_	NumType=Card	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	1549	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	SYM	_	_	_	_	_	_
6	1560	_	NUM	_	NumType=Card	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	directs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	type	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	reporter	_	NOUN	_	Number=Sing	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	lines	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
29	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	own	_	ADJ	_	Degree=Pos	_	_	_	_
32	promoter	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
36	loop	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	murine	_	PROPN	_	Number=Sing	_	_	_	_
7	PU.	_	NOUN	_	Number=Sing	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	specifically	_	ADV	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	highly	_	ADV	_	_	_	_	_	_
15	functional	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	B	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	lines	_	NOUN	_	Number=Plur	_	_	_	_
20	as	_	ADV	_	_	_	_	_	_
21	well	_	ADV	_	Degree=Pos	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Oct	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Oct	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
10	specifically	_	ADV	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	base	_	NOUN	_	Number=Sing	_	_	_	_
16	pair	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	55	_	NUM	_	NumType=Card	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	vitro	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	specifically	_	ADV	_	_	_	_	_	_
27	protected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	B	_	ADJ	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	vivo	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	sites	_	NOUN	_	Number=Plur	_	_	_	_
8	contribute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	promoter	_	VERB	_	VerbForm=Inf	_	_	_	_
11	activity	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	B	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	;	_	PUNCT	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	site	_	NOUN	_	Number=Sing	_	_	_	_
20	adjacent	_	VERB	_	VerbForm=Ger	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	octamer	_	NOUN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	PU.	_	PROPN	_	Number=Sing	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
10	OBF	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1/Bob1/OCA	_	NOUN	_	Number=Sing	_	_	_	_
13	-B	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	only	_	ADV	_	_	_	_	_	_
16	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	B	_	ADJ	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	OBF	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1/Bob1/OCA	_	NOUN	_	Number=Sing	_	_	_	_
31	-B	_	NOUN	_	Number=Sing	_	_	_	_
32	can	_	AUX	_	VerbForm=Fin	_	_	_	_
33	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	PU.1	_	PROPN	_	Number=Sing	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	B	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
17	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	octamer	_	NOUN	_	Number=Sing	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012770	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	interferon	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	gamma	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	IgG	_	PROPN	_	Number=Sing	_	_	_	_
14	Fc	_	PROPN	_	Number=Sing	_	_	_	_
15	receptor	_	NOUN	_	Number=Sing	_	_	_	_
16	type	_	NOUN	_	Number=Sing	_	_	_	_
17	IC	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	interferon	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	gamma	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	IgG	_	PROPN	_	Number=Sing	_	_	_	_
5	Fc	_	PROPN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	type	_	NOUN	_	Number=Sing	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	Fc	_	PROPN	_	Number=Sing	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	RI	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	dramatically	_	ADV	_	_	_	_	_	_
19	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	treatment	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	interferon	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	gamma	_	NOUN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	IFN	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	gamma	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	observed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	Fc	_	PROPN	_	Number=Sing	_	_	_	_
5	gamma	_	PROPN	_	Number=Sing	_	_	_	_
6	RI	_	PROPN	_	Number=Sing	_	_	_	_
7	transcript	_	NOUN	_	Number=Sing	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	monoblast	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	like	_	ADJ	_	Degree=Pos	_	_	_	_
13	U937	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	elevated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	within	_	ADP	_	_	_	_	_	_
18	3	_	NUM	_	NumType=Card	_	_	_	_
19	hr	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	peaked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	12	_	NUM	_	NumType=Card	_	_	_	_
23	hr	_	NOUN	_	Number=Sing	_	_	_	_
24	after	_	ADP	_	_	_	_	_	_
25	exposure	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	IFN	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	gamma	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	U937	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	IFN	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	9	_	NUM	_	NumType=Card	_	_	_	_
10	hr	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	presence	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
16	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	super	_	ADJ	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induction	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	Fc	_	PROPN	_	Number=Sing	_	_	_	_
23	gamma	_	NOUN	_	Number=Sing	_	_	_	_
24	RI	_	PROPN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	run	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	analysis	_	NOUN	_	Number=Sing	_	_	_	_
6	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	rate	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Fc	_	PROPN	_	Number=Sing	_	_	_	_
12	gamma	_	NOUN	_	Number=Sing	_	_	_	_
13	RI	_	PROPN	_	Number=Sing	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	IFN	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	gamma	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Genomic	_	ADJ	_	Degree=Pos	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	upstream	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	Fc	_	PROPN	_	Number=Sing	_	_	_	_
7	gamma	_	NOUN	_	Number=Sing	_	_	_	_
8	RIC	_	PROPN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	cloned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	subjected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	primer	_	ADJ	_	Degree=Pos	_	_	_	_
16	extension	_	NOUN	_	Number=Sing	_	_	_	_
17	analysis	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	single	_	ADJ	_	Degree=Pos	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	initiation	_	NOUN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	without	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	TATA	_	NOUN	_	Number=Sing	_	_	_	_
29	box	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	transfections	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	CAT	_	NOUN	_	Number=Sing	_	_	_	_
5	reporter	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	constructs	_	NOUN	_	Number=Plur	_	_	_	_
8	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	various	_	ADJ	_	Degree=Pos	_	_	_	_

1	Fc	_	PROPN	_	Number=Sing	_	_	_	_
2	gamma	_	NOUN	_	Number=Sing	_	_	_	_
3	RIC	_	NOUN	_	Number=Sing	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	sequences	_	NOUN	_	Number=Plur	_	_	_	_
6	into	_	ADP	_	_	_	_	_	_
7	U937	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	20	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	bp	_	NOUN	_	Number=Sing	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	surrounding	_	VERB	_	VerbForm=Ger	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	start	_	NOUN	_	Number=Sing	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	-	_	SYM	_	_	_	_	_	_
23	7	_	NUM	_	NumType=Card	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	+	_	SYM	_	_	_	_	_	_
26	13	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	capable	_	ADJ	_	Degree=Pos	_	_	_	_
30	of	_	SCONJ	_	_	_	_	_	_
31	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	initiation	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	that	_	SCONJ	_	_	_	_	_	_
36	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	IFN	_	ADJ	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	gamma	_	NOUN	_	Number=Sing	_	_	_	_
40	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
41	element	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	GIRE	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
46	present	_	ADJ	_	Degree=Pos	_	_	_	_
47	within	_	ADP	_	_	_	_	_	_
48	74	_	NUM	_	NumType=Card	_	_	_	_
49	bp	_	NOUN	_	Number=Sing	_	_	_	_
50	upstream	_	NOUN	_	Number=Sing	_	_	_	_
51	of	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	transcription	_	NOUN	_	Number=Sing	_	_	_	_
54	initiation	_	NOUN	_	Number=Sing	_	_	_	_
55	site	_	NOUN	_	Number=Sing	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	17	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	bp	_	NOUN	_	Number=Sing	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	between	_	ADP	_	_	_	_	_	_
7	positions	_	NOUN	_	Number=Plur	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	51	_	NUM	_	NumType=Card	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	35	_	NUM	_	NumType=Card	_	_	_	_
13	conferred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	IFN	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	gamma	_	NOUN	_	Number=Sing	_	_	_	_
17	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Double	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	stranded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	GIRE	_	PROPN	_	Number=Sing	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	but	_	CCONJ	_	_	_	_	_	_
8	not	_	ADV	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	scrambled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	specifically	_	ADV	_	_	_	_	_	_
15	bound	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	IFN	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	gamma	_	NOUN	_	Number=Sing	_	_	_	_
23	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	U937	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	shift	_	NOUN	_	Number=Sing	_	_	_	_
3	experiments	_	NOUN	_	Number=Plur	_	_	_	_
4	further	_	ADV	_	_	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	bound	_	ADJ	_	Degree=Pos	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	Fc	_	PROPN	_	Number=Sing	_	_	_	_
15	gamma	_	NOUN	_	Number=Sing	_	_	_	_
16	RIC	_	PROPN	_	Number=Sing	_	_	_	_
17	GIRE	_	PROPN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	IFN	_	ADJ	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	gamma	_	NOUN	_	Number=Sing	_	_	_	_
24	treatment	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	U937	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Fc	_	PROPN	_	Number=Sing	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	RIC	_	PROPN	_	Number=Sing	_	_	_	_
5	GIRE	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	IFN	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	gamma	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	GAS	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	guanylate	_	NOUN	_	Number=Sing	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	protein	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	X	_	NOUN	_	Number=Sing	_	_	_	_
26	box	_	NOUN	_	Number=Sing	_	_	_	_
27	elements	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	class	_	NOUN	_	Number=Sing	_	_	_	_
30	II	_	NUM	_	NumType=Card	_	_	_	_
31	MHC	_	NOUN	_	Number=Sing	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	Fc	_	PROPN	_	Number=Sing	_	_	_	_
10	gamma	_	NOUN	_	Number=Sing	_	_	_	_
11	RIC	_	PROPN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	IFN	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	gamma	_	NOUN	_	Number=Sing	_	_	_	_
17	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	17	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	bp	_	NOUN	_	Number=Sing	_	_	_	_
28	GAS	_	NOUN	_	Number=Sing	_	_	_	_
29	homology	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012790	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Central	_	ADJ	_	Degree=Pos	_	_	_	_
2	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
3	system	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	enhances	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	type	_	NOUN	_	Number=Sing	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	vitro	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	facilitates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	TAR	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	independent	_	ADJ	_	Degree=Pos	_	_	_	_
29	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	Tat	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Tat	_	NOUN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	potent	_	ADJ	_	Degree=Pos	_	_	_	_
18	activator	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	long	_	ADJ	_	Degree=Pos	_	_	_	_
21	terminal	_	NOUN	_	Number=Sing	_	_	_	_
22	repeat	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	While	_	SCONJ	_	_	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	most	_	ADJ	_	Degree=Sup	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	types	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	interaction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	Tat	_	NOUN	_	Number=Sing	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	unusual	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	TAR	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	astrocytic	_	ADJ	_	Degree=Pos	_	_	_	_
20	glial	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	support	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	TAR	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	independent	_	ADJ	_	Degree=Pos	_	_	_	_
26	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	HIV	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	Tat	_	PROPN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
3	pathway	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Tat	_	PROPN	_	Number=Sing	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	viral	_	ADJ	_	Degree=Pos	_	_	_	_
12	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	domain	_	NOUN	_	Number=Sing	_	_	_	_
18	capable	_	ADJ	_	Degree=Pos	_	_	_	_
19	of	_	SCONJ	_	_	_	_	_	_
20	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	prototypical	_	ADJ	_	Degree=Pos	_	_	_	_
23	form	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	NF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	present	_	VERB	_	Degree=Pos	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	many	_	ADJ	_	Degree=Pos	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	types	_	NOUN	_	Number=Plur	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	including	_	VERB	_	VerbForm=Ger	_	_	_	_
45	T	_	PROPN	_	Number=Sing	_	_	_	_
46	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Tat	_	PROPN	_	Number=Sing	_	_	_	_
2	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
3	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	domain	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	allow	_	VERB	_	VerbForm=Inf	_	_	_	_
13	replication	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	TAR	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	mutant	_	ADJ	_	Degree=Pos	_	_	_	_
19	HIV	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	astrocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	existence	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	present	_	VERB	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	glial	_	ADJ	_	Degree=Pos	_	_	_	_
18	astrocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	from	_	ADP	_	_	_	_	_	_
22	prototypical	_	ADJ	_	Degree=Pos	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	PROPN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	astrocyte	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	retained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	Tat	_	NOUN	_	Number=Sing	_	_	_	_
19	affinity	_	NOUN	_	Number=Sing	_	_	_	_
20	column	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	while	_	SCONJ	_	_	_	_	_	_
23	prototypical	_	ADJ	_	Degree=Pos	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
30	T	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	not	_	PART	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	astrocyte	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	HIV	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	long	_	ADJ	_	Degree=Pos	_	_	_	_
23	terminal	_	NOUN	_	Number=Sing	_	_	_	_
24	repeat	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	that	_	SCONJ	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
31	on	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	kappa	_	PROPN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	domain	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	TAR	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	independent	_	ADJ	_	Degree=Pos	_	_	_	_
6	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	reproduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	vitro	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	astrocyte	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	manner	_	NOUN	_	Number=Sing	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	importance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	central	_	ADJ	_	Degree=Pos	_	_	_	_
6	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
7	system	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	enriched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	HIV	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012807	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	YY1	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Oct1	_	PROPN	_	Number=Sing	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	novel	_	NOUN	_	Number=Sing	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	_	_	_	_	_
11	downregulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	5	_	NUM	_	NumType=Card	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	controls	_	NOUN	_	Number=Plur	_	_	_	_
7	development	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	eosinophilia	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	involved	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	allergic	_	ADJ	_	Degree=Pos	_	_	_	_
22	diseases	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	both	_	CCONJ	_	_	_	_	_	_
3	atopic	_	ADJ	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	nonatopic	_	ADJ	_	Degree=Pos	_	_	_	_
6	asthma	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	elevated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	5	_	NUM	_	NumType=Card	_	_	_	_
12	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
17	blood	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	airways	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	5	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	mainly	_	ADV	_	_	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	OBJECTIVE	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	focuses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	functional	_	ADJ	_	Degree=Pos	_	_	_	_
7	analysis	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	IL	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	5	_	NUM	_	NumType=Card	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	hIL	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	5	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	characterization	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	cis	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
26	elements	_	NOUN	_	Number=Plur	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	factors	_	NOUN	_	Number=Plur	_	_	_	_
30	involved	_	ADJ	_	Degree=Pos	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	suppression	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	5	_	NUM	_	NumType=Card	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	T	_	PROPN	_	Number=Sing	_	_	_	_
41	cells	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Methods	_	NOUN	_	Number=Plur	_	_	_	_
4	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	study	_	NOUN	_	Number=Sing	_	_	_	_
8	include	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	DNase	_	NOUN	_	Number=Sing	_	_	_	_
10	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
11	footprint	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	assays	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
15	mobility	_	NOUN	_	Number=Sing	_	_	_	_
16	shift	_	NOUN	_	Number=Sing	_	_	_	_
17	assays	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	functional	_	ADJ	_	Degree=Pos	_	_	_	_
21	analysis	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	mammalian	_	ADJ	_	Degree=Pos	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	transfection	_	NOUN	_	Number=Sing	_	_	_	_
26	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
27	deletion	_	NOUN	_	Number=Sing	_	_	_	_
28	analysis	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	site	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	mutagenesis	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	5	_	NUM	_	NumType=Card	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	VERB	_	Number=Sing	_	_	_	_
6	regions	_	NOUN	_	Number=Plur	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	BRs	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
14	hIL	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	5	_	NUM	_	NumType=Card	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	BRs	_	NOUN	_	Number=Sing	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	involved	_	ADJ	_	Degree=Pos	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	control	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	hIL	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	5	_	NUM	_	NumType=Card	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	regions	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	BR3	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	BR4	_	PROPN	_	Number=Sing	_	_	_	_
9	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	positions	_	NOUN	_	Number=Plur	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	102	_	NUM	_	NumType=Card	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	-	_	SYM	_	_	_	_	_	_
16	73	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	previously	_	ADV	_	_	_	_	_	_
21	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
22	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	regulators	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	5	_	NUM	_	NumType=Card	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	T	_	PROPN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	BR3	_	PROPN	_	Number=Sing	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	novel	_	NOUN	_	Number=Sing	_	_	_	_
10	negative	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	positions	_	NOUN	_	Number=Plur	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	90	_	NUM	_	NumType=Card	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	79	_	NUM	_	NumType=Card	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	hIL	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	5	_	NUM	_	NumType=Card	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	which	_	PRON	_	PronType=Rel	_	_	_	_
29	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	Oct1	_	PROPN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	octamer	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	like	_	ADP	_	Degree=Pos	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	YY1	_	PROPN	_	Number=Sing	_	_	_	_
38	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
39	factors	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Substitution	_	NOUN	_	Number=Sing	_	_	_	_
2	mutations	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	abolished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	BR3	_	PROPN	_	Number=Sing	_	_	_	_
13	sequence	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	significantly	_	ADV	_	_	_	_	_	_
16	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	hIL	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	SYM	_	_	_	_	_	_
19	5	_	NUM	_	NumType=Card	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSION	_	NOUN	_	Number=Sing	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	Oct1	_	PROPN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	YY1	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	octamer	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	like	_	ADJ	_	Degree=Pos	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	90/-79	_	NUM	_	NumType=Card	_	_	_	_
18	sequence	_	NOUN	_	Number=Sing	_	_	_	_
19	within	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	5	_	NUM	_	NumType=Card	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	involved	_	ADJ	_	Degree=Pos	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	suppression	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	5	_	NUM	_	NumType=Card	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	T	_	PROPN	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012808	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	BSAP	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	Pax	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	development	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	hierarchy	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	control	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	development	_	NOUN	_	Number=Sing	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	recently	_	ADV	_	_	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	mouse	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	manner	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	paired	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
7	box	_	NOUN	_	Number=Sing	_	_	_	_
8	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	Pax	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	5	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	BSAP	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
25	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	play	_	VERB	_	VerbForm=Inf	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	key	_	ADJ	_	Degree=Pos	_	_	_	_
30	role	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	early	_	ADJ	_	Degree=Pos	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	lymphopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Other	_	ADJ	_	Degree=Pos	_	_	_	_
2	experimental	_	ADJ	_	Degree=Pos	_	_	_	_
3	strategies	_	NOUN	_	Number=Plur	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	implicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	BSAP	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	control	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	isotype	_	NOUN	_	Number=Sing	_	_	_	_
15	switching	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
21	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	chain	_	NOUN	_	Number=Sing	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	at	_	ADP	_	_	_	_	_	_
26	late	_	ADJ	_	Degree=Pos	_	_	_	_
27	stages	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012809	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Elf	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Stat5	_	PROPN	_	Number=Sing	_	_	_	_
6	bind	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	critical	_	ADJ	_	Degree=Pos	_	_	_	_
10	element	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	new	_	ADJ	_	Degree=Pos	_	_	_	_
14	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	[	_	PUNCT	_	_	_	_	_	_
25	published	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	erratum	_	NOUN	_	Number=Sing	_	_	_	_
27	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	Mol	_	NOUN	_	Number=Sing	_	_	_	_
30	Cell	_	NOUN	_	Number=Sing	_	_	_	_
31	Biol	_	NOUN	_	Number=Sing	_	_	_	_
32	1997	_	NUM	_	NumType=Card	_	_	_	_
33	Apr	_	PROPN	_	Number=Sing	_	_	_	_
34	;	_	PUNCT	_	_	_	_	_	_
35	17	_	NUM	_	NumType=Card	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	4	_	NUM	_	NumType=Card	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	:	_	PUNCT	_	_	_	_	_	_
40	2351	_	NUM	_	NumType=Card	_	_	_	_
41	]	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	receptor	_	NOUN	_	Number=Sing	_	_	_	_
5	alpha-chain	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	2R	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	key	_	ADJ	_	Degree=Pos	_	_	_	_
16	regulator	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2R	_	PROPN	_	Number=Sing	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	rapidly	_	ADV	_	_	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	potently	_	ADV	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	mitogenic	_	ADJ	_	Degree=Pos	_	_	_	_
17	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	2	_	NUM	_	NumType=Card	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2R	_	NUM	_	Number=Sing	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	thereby	_	ADV	_	_	_	_	_	_
16	amplifying	_	VERB	_	VerbForm=Ger	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	own	_	ADJ	_	Degree=Pos	_	_	_	_
21	high	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	affinity	_	NOUN	_	Number=Sing	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2R	_	PROPN	_	Number=Sing	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	at	_	ADV	_	_	_	_	_	_
8	least	_	ADV	_	Degree=Sup	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	part	_	NOUN	_	Number=Sing	_	_	_	_
11	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	two	_	NUM	_	NumType=Card	_	_	_	_
14	positive	_	ADJ	_	Degree=Pos	_	_	_	_
15	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	regions	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	PRRI	_	PROPN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	PRRII	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	PRRI	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
5	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
6	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	276	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	244	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	SRE	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	CArG	_	NOUN	_	Number=Sing	_	_	_	_
26	motifs	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	PRRII	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	137	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	-	_	SYM	_	_	_	_	_	_
16	64	_	NUM	_	NumType=Card	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	specific	_	ADJ	_	Degree=Pos	_	_	_	_
24	Ets	_	NOUN	_	Number=Plur	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	Elf	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	HMG	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	Y	_	X	_	_	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	proteins	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	none	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
7	regions	_	NOUN	_	Number=Plur	_	_	_	_
8	account	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2R	_	NOUN	_	Number=Sing	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	find	_	VERB	_	VerbForm=Inf	_	_	_	_
3	new	_	ADJ	_	Degree=Pos	_	_	_	_
4	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
5	regions	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2R	_	NOUN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	8.5	_	NUM	_	NumType=Card	_	_	_	_
15	kb	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	5	_	NUM	_	NumType=Card	_	_	_	_
19	'	_	PUNCT	_	_	_	_	_	_
20	end	_	NOUN	_	Number=Sing	_	_	_	_
21	noncoding	_	NOUN	_	Number=Sing	_	_	_	_
22	sequence	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2R	_	NOUN	_	Number=Sing	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
32	sequenced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	86	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	nucleotide	_	NOUN	_	Degree=Pos	_	_	_	_
7	fragment	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	90	_	NUM	_	NumType=Card	_	_	_	_
11	%	_	SYM	_	Number=Sing	_	_	_	_
12	identical	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	recently	_	ADV	_	_	_	_	_	_
16	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	murine	_	ADJ	_	Number=Sing	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
23	element	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	mIL	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2rE	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	putative	_	ADJ	_	Degree=Pos	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2rE	_	NUM	_	NumType=Card	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	PRRIII	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	confers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	PRRIII	_	PROPN	_	Number=Sing	_	_	_	_
2	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	Stat	_	PROPN	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	overlaps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	EBS	_	PROPN	_	Number=Sing	_	_	_	_
13	motif	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	GASd	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	EBSd	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	essential	_	ADJ	_	Degree=Pos	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	PRRIII	_	PROPN	_	Number=Sing	_	_	_	_
11	/	_	PUNCT	_	_	_	_	_	_
12	CAT	_	NOUN	_	Number=Sing	_	_	_	_
13	reporter	_	NOUN	_	Number=Sing	_	_	_	_
14	constructs	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Stat5a	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	b	_	PROPN	_	Number=Sing	_	_	_	_
11	proteins	_	VERB	_	Number=Plur	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	GASd	_	NOUN	_	Number=Sing	_	_	_	_
16	element	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	confirm	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
5	relevance	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	findings	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
11	carried	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	out	_	ADP	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vivo	_	NOUN	_	Number=Sing	_	_	_	_
15	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
16	experiments	_	NOUN	_	Number=Plur	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2R	_	NOUN	_	Number=Sing	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	occupancy	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	GASd	_	NOUN	_	Number=Sing	_	_	_	_
33	element	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	major	_	ADJ	_	Degree=Pos	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	GASd	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	EBSd	_	NOUN	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2R	_	NOUN	_	Number=Sing	_	_	_	_
17	alpha	_	NOUN	_	Number=Sing	_	_	_	_
18	regulation	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	Elf	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	factor	_	NOUN	_	Number=Sing	_	_	_	_
30	can	_	AUX	_	VerbForm=Fin	_	_	_	_
31	serve	_	VERB	_	VerbForm=Inf	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
35	repressor	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012812	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulator	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	c-myb	_	ADJ	_	Degree=Pos	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Resting	_	VERB	_	VerbForm=Ger	_	_	_	_
2	T	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	express	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	very	_	ADV	_	_	_	_	_	_
6	low	_	ADJ	_	Degree=Pos	_	_	_	_
7	levels	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	c	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	Myb	_	NOUN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	During	_	ADP	_	_	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	c-myb	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	much	_	ADJ	_	Degree=Pos	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	increase	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	occurs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	at	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	level	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	c-myb	_	NOUN	_	Number=Sing	_	_	_	_
8	5	_	NUM	_	NumType=Card	_	_	_	_
9	'	_	PUNCT	_	_	_	_	_	_
10	flanking	_	NOUN	_	Number=Sing	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	c-myb	_	NOUN	_	Degree=Pos	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	during	_	ADP	_	_	_	_	_	_
17	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vivo	_	NOUN	_	Number=Sing	_	_	_	_
3	footprinting	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	ligation	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	PCR	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	performed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	correlate	_	VERB	_	VerbForm=Inf	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vivo	_	NOUN	_	Number=Sing	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	functional	_	ADJ	_	Degree=Pos	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	footprint	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	visible	_	ADJ	_	Degree=Pos	_	_	_	_
6	over	_	ADP	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	region	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	c-myb	_	NOUN	_	Number=Sing	_	_	_	_
12	5	_	NUM	_	NumType=Card	_	_	_	_
13	'	_	PUNCT	_	_	_	_	_	_
14	flanking	_	NOUN	_	Number=Sing	_	_	_	_
15	sequence	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	unactivated	_	ADJ	_	Degree=Pos	_	_	_	_
24	T	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assay	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	extract	_	NOUN	_	Number=Sing	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	new	_	ADJ	_	Degree=Pos	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	DNA	_	PROPN	_	Number=Sing	_	_	_	_
29	complex	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	referred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	as	_	ADP	_	_	_	_	_	_
34	CMAT	_	PROPN	_	Number=Sing	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	c-myb	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	T	_	NOUN	_	Number=Sing	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	;	_	PUNCT	_	_	_	_	_	_
42	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
43	complex	_	NOUN	_	Number=Sing	_	_	_	_
44	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
45	not	_	PART	_	_	_	_	_	_
46	present	_	ADJ	_	Degree=Pos	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	unactivated	_	ADJ	_	Degree=Pos	_	_	_	_
49	T	_	NOUN	_	Number=Sing	_	_	_	_
50	cells	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	site	_	NOUN	_	Number=Sing	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	some	_	DET	_	_	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	similarity	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	T	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
24	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	induction	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	two	_	NUM	_	NumType=Card	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	complexes	_	NOUN	_	Number=Plur	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
37	masses	_	NOUN	_	Number=Plur	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	two	_	NUM	_	NumType=Card	_	_	_	_
41	proteins	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	induction	_	NOUN	_	Number=Sing	_	_	_	_
7	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
11	EMSA	_	PROPN	_	Number=Sing	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	complex	_	NOUN	_	Number=Sing	_	_	_	_
14	appeared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	earlier	_	ADV	_	Degree=Cmp	_	_	_	_
16	than	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	CMAT	_	PROPN	_	Number=Sing	_	_	_	_
19	complex	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	migrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	more	_	ADV	_	_	_	_	_	_
6	slowly	_	ADV	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	sodium	_	NOUN	_	Number=Sing	_	_	_	_
10	dodecyl	_	NOUN	_	Number=Sing	_	_	_	_
11	sulfate	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	polyacrylamide	_	NOUN	_	Number=Sing	_	_	_	_
14	gel	_	NOUN	_	Number=Sing	_	_	_	_
15	than	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	CMAT	_	PROPN	_	Number=Sing	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	did	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	antibody	_	NOUN	_	Number=Sing	_	_	_	_
6	against	_	ADP	_	_	_	_	_	_
7	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
8	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	cross	_	VERB	_	VerbForm=Inf	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	react	_	VERB	_	VerbForm=Inf	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	CMAT	_	NOUN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	appearance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	CMAT	_	PROPN	_	Number=Sing	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	complex	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	both	_	CCONJ	_	_	_	_	_	_
12	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
13	A	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	rapamycin	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CMAT	_	PROPN	_	Number=Sing	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	novel	_	NOUN	_	Number=Sing	_	_	_	_
9	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	involved	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	c-myb	_	ADJ	_	Degree=Pos	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	during	_	ADP	_	_	_	_	_	_
19	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012813	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Unicellular	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	unilineage	_	ADJ	_	Degree=Pos	_	_	_	_
4	erythropoietic	_	ADJ	_	Degree=Pos	_	_	_	_
5	cultures	_	NOUN	_	Number=Plur	_	_	_	_
6	:	_	PUNCT	_	_	_	_	_	_
7	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
8	analysis	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	sibling	_	NOUN	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	level	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
6	control	_	NOUN	_	Number=Sing	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	hampered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	heterogeneity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	populations	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	ie	_	X	_	_	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	lack	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	lineage	_	NOUN	_	Number=Sing	_	_	_	_
25	specificity	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
28	stage	_	NOUN	_	Number=Sing	_	_	_	_
29	homogeneity	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	precursor	_	NOUN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	growing	_	VERB	_	VerbForm=Ger	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	culture	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	developed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	unicellular	_	ADJ	_	Degree=Pos	_	_	_	_
4	culture	_	NOUN	_	Number=Sing	_	_	_	_
5	systems	_	NOUN	_	Number=Plur	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	unilineage	_	ADJ	_	Degree=Pos	_	_	_	_
8	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	purified	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
11	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
12	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	daughter	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	analysis	_	NOUN	_	Number=Sing	_	_	_	_
19	at	_	ADP	_	_	_	_	_	_
20	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
23	level	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	culture	_	NOUN	_	Number=Sing	_	_	_	_
4	system	_	NOUN	_	Number=Sing	_	_	_	_
5	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	here	_	ADV	_	PronType=Dem	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	1	_	X	_	_	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	GF	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	stimulus	_	NOUN	_	Degree=Pos	_	_	_	_
18	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	cord	_	NOUN	_	Number=Sing	_	_	_	_
20	blood	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	CB	_	NOUN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	proliferate	_	VERB	_	VerbForm=Inf	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	differentiate	_	VERB	_	Degree=Pos	_	_	_	_
30	/	_	PUNCT	_	_	_	_	_	_
31	mature	_	ADJ	_	Degree=Pos	_	_	_	_
32	exclusively	_	ADV	_	_	_	_	_	_
33	along	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
36	lineage	_	NOUN	_	Number=Sing	_	_	_	_
37	;	_	PUNCT	_	_	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	2	_	X	_	_	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
42	erythropoietic	_	ADJ	_	Degree=Pos	_	_	_	_
43	wave	_	NOUN	_	Number=Sing	_	_	_	_
44	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
46	by	_	ADP	_	_	_	_	_	_
47	less	_	ADJ	_	Degree=Cmp	_	_	_	_
48	than	_	ADP	_	_	_	_	_	_
49	4	_	NUM	_	NumType=Card	_	_	_	_
50	%	_	SYM	_	Number=Sing	_	_	_	_
51	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
52	cells	_	NOUN	_	Number=Plur	_	_	_	_
53	;	_	PUNCT	_	_	_	_	_	_
54	(	_	PUNCT	_	_	_	_	_	_
55	3	_	X	_	_	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	asymmetric	_	ADJ	_	Degree=Pos	_	_	_	_
58	divisions	_	NOUN	_	Number=Plur	_	_	_	_
59	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
60	virtually	_	ADV	_	_	_	_	_	_
61	absent	_	ADJ	_	Degree=Pos	_	_	_	_
62	,	_	PUNCT	_	_	_	_	_	_
63	ie	_	X	_	_	_	_	_	_
64	,	_	PUNCT	_	_	_	_	_	_
65	nonresponsive	_	ADJ	_	Degree=Pos	_	_	_	_
66	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
67	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
68	with	_	ADP	_	_	_	_	_	_
69	no	_	DET	_	_	_	_	_	_
70	erythropoietic	_	ADJ	_	Degree=Pos	_	_	_	_
71	potential	_	NOUN	_	Number=Sing	_	_	_	_
72	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
73	forced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
74	into	_	ADP	_	_	_	_	_	_
75	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
76	;	_	PUNCT	_	_	_	_	_	_
77	(	_	PUNCT	_	_	_	_	_	_
78	4	_	X	_	_	_	_	_	_
79	)	_	PUNCT	_	_	_	_	_	_
80	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
81	system	_	NOUN	_	Number=Sing	_	_	_	_
82	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
83	cell	_	NOUN	_	Number=Sing	_	_	_	_
84	division	_	NOUN	_	Number=Sing	_	_	_	_
85	controlled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
86	(	_	PUNCT	_	_	_	_	_	_
87	cdc	_	NOUN	_	Number=Sing	_	_	_	_
88	)	_	PUNCT	_	_	_	_	_	_
89	,	_	PUNCT	_	_	_	_	_	_
90	ie	_	X	_	_	_	_	_	_
91	,	_	PUNCT	_	_	_	_	_	_
92	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
93	number	_	NOUN	_	Number=Sing	_	_	_	_
94	of	_	ADP	_	_	_	_	_	_
95	divisions	_	NOUN	_	Number=Plur	_	_	_	_
96	performed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
97	by	_	ADP	_	_	_	_	_	_
98	each	_	DET	_	_	_	_	_	_
99	cell	_	NOUN	_	Number=Sing	_	_	_	_
100	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
101	monitored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
102	.	_	PUNCT	_	_	_	_	_	_

1	Single	_	ADJ	_	Degree=Pos	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	reverse	_	NOUN	_	Number=Sing	_	_	_	_
5	transcriptase	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
8	chain	_	NOUN	_	Number=Sing	_	_	_	_
9	reaction	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	RT	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	PCR	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	analysis	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	applied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
20	culture	_	NOUN	_	Number=Sing	_	_	_	_
21	system	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
28	receptors	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	markers	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	transcription	_	NOUN	_	Number=Sing	_	_	_	_
36	factors	_	NOUN	_	Number=Plur	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	GATA	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	GATA	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	2	_	NUM	_	NumType=Card	_	_	_	_
47	,	_	PUNCT	_	_	_	_	_	_
48	p45	_	NOUN	_	Number=Sing	_	_	_	_
49	NF	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	E2	_	NUM	_	Number=Sing	_	_	_	_
52	,	_	PUNCT	_	_	_	_	_	_
53	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	and	_	CCONJ	_	_	_	_	_	_
56	SCL	_	PROPN	_	Number=Sing	_	_	_	_
57	/	_	PUNCT	_	_	_	_	_	_
58	Tal1	_	NOUN	_	Number=Sing	_	_	_	_
59	)	_	PUNCT	_	_	_	_	_	_
60	at	_	ADP	_	_	_	_	_	_
61	discrete	_	ADJ	_	Degree=Pos	_	_	_	_
62	stages	_	NOUN	_	Number=Plur	_	_	_	_
63	of	_	ADP	_	_	_	_	_	_
64	erythropoietic	_	ADJ	_	Degree=Pos	_	_	_	_
65	development	_	NOUN	_	Number=Sing	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	Freshly	_	ADV	_	_	_	_	_	_
2	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	CD34	_	PROPN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	+	_	SYM	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	CD34	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	c-kit	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	GATA	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	not	_	PART	_	_	_	_	_	_
22	express	_	VERB	_	VerbForm=Inf	_	_	_	_
23	CD36	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	EpoR	_	PROPN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	SCL	_	PROPN	_	Number=Sing	_	_	_	_
32	/	_	PUNCT	_	_	_	_	_	_
33	Tal1	_	PROPN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	E2	_	PROPN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	GATA	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	1	_	NUM	_	NumType=Card	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	or	_	CCONJ	_	_	_	_	_	_
46	glyocophorin	_	NOUN	_	Number=Sing	_	_	_	_
47	A	_	NOUN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	GPA	_	NOUN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	early	_	ADJ	_	Degree=Pos	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	intermediate	_	ADJ	_	Degree=Pos	_	_	_	_
5	stages	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
8	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
9	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
10	monitored	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	CD36	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	Tal1	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	NF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	E2	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	GATA	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	that	_	DET	_	PronType=Rel	_	_	_	_
29	preceeded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	EpoR	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	late	_	ADJ	_	Degree=Pos	_	_	_	_
3	stages	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
6	maturation	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	GPA	_	PROPN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	upregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	whereas	_	SCONJ	_	_	_	_	_	_
13	CD34	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	c-kit	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	PU.1	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	GATA	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	barely	_	ADV	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	competitive	_	ADJ	_	Degree=Pos	_	_	_	_
5	single	_	ADJ	_	Degree=Pos	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	RT	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	PCR	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	assay	_	VERB	_	VerbForm=Inf	_	_	_	_
15	CD34	_	PROPN	_	Number=Sing	_	_	_	_
16	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
17	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	sibling	_	VERB	_	VerbForm=Ger	_	_	_	_
20	CD34	_	PROPN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	+	_	SYM	_	_	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	CD38	_	PROPN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	-)	_	PUNCT	_	_	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	unilineage	_	ADJ	_	Degree=Pos	_	_	_	_
31	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
32	cultures	_	NOUN	_	Number=Plur	_	_	_	_
33	:	_	PUNCT	_	_	_	_	_	_
34	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
35	analysis	_	NOUN	_	Number=Sing	_	_	_	_
36	allowed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
37	us	_	PRON	_	Case=Acc|Number=Plur|Person=1|PronType=Prs	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	semiquantitate	_	VERB	_	VerbForm=Inf	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	gradual	_	ADJ	_	Degree=Pos	_	_	_	_
42	downmodulation	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	CD34	_	PROPN	_	Number=Sing	_	_	_	_
45	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
46	from	_	ADP	_	_	_	_	_	_
47	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
48	cells	_	NOUN	_	Number=Plur	_	_	_	_
49	through	_	ADP	_	_	_	_	_	_
50	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
51	differentiating	_	NOUN	_	Degree=Pos	_	_	_	_
52	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
53	progeny	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	concluded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	novel	_	NOUN	_	Number=Sing	_	_	_	_
7	culture	_	NOUN	_	Number=Sing	_	_	_	_
8	system	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	single	_	ADJ	_	Degree=Pos	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	RT	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	PCR	_	NOUN	_	Number=Sing	_	_	_	_
18	analysis	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	eliminate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	ambiguities	_	NOUN	_	Number=Plur	_	_	_	_
24	intrinsic	_	ADJ	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
27	studies	_	NOUN	_	Number=Plur	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	heterogeneous	_	ADJ	_	Degree=Pos	_	_	_	_
30	populations	_	NOUN	_	Number=Plur	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
33	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	precursors	_	NOUN	_	Number=Plur	_	_	_	_
36	growing	_	VERB	_	VerbForm=Ger	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	culture	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	particularly	_	ADV	_	_	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	initial	_	ADJ	_	Degree=Pos	_	_	_	_
44	stages	_	NOUN	_	Number=Plur	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	development	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012817	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	bcl	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	phosphorylated	_	VERB	_	Degree=Pos	_	_	_	_
9	CREB	_	NOUN	_	Number=Sing	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	rescue	_	NOUN	_	Number=Sing	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Engagement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	surface	_	NOUN	_	Number=Sing	_	_	_	_
4	immunoglobulin	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	mature	_	ADJ	_	Degree=Pos	_	_	_	_
7	B	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	rescue	_	VERB	_	VerbForm=Inf	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Levels	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	bcl	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	increase	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	cross	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	linking	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	surface	_	NOUN	_	Number=Sing	_	_	_	_
16	immunoglobulin	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	major	_	ADJ	_	Degree=Pos	_	_	_	_
6	positive	_	ADJ	_	Degree=Pos	_	_	_	_
7	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	region	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	control	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	bcl	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	B	_	ADJ	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	5'-	_	NOUN	_	Number=Sing	_	_	_	_
22	flanking	_	VERB	_	Number=Sing	_	_	_	_
23	region	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	positive	_	ADJ	_	Degree=Pos	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	can	_	AUX	_	VerbForm=Fin	_	_	_	_
5	be	_	AUX	_	VerbForm=Inf	_	_	_	_
6	divided	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	into	_	ADP	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	upstream	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
13	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	region	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
3	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
4	region	_	NOUN	_	Number=Sing	_	_	_	_
5	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	cyclic	_	ADJ	_	Degree=Pos	_	_	_	_
8	AMP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
11	element	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	CRE	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	antibody	_	ADJ	_	Number=Sing	_	_	_	_
5	supershift	_	NOUN	_	Number=Sing	_	_	_	_
6	experiments	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	UV	_	PROPN	_	Number=Sing	_	_	_	_
9	cross	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	linking	_	NOUN	_	Number=Sing	_	_	_	_
12	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	denaturing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	polyacrylamide	_	ADJ	_	Number=Sing	_	_	_	_
16	gel	_	NOUN	_	Number=Sing	_	_	_	_
17	electrophoresis	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	CREB	_	PROPN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	ATF	_	PROPN	_	Number=Sing	_	_	_	_
23	family	_	NOUN	_	Number=Sing	_	_	_	_
24	members	_	NOUN	_	Number=Plur	_	_	_	_
25	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	region	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	vitro	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CRE	_	NOUN	_	Number=Sing	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	that	_	DET	_	PronType=Rel	_	_	_	_
7	result	_	VERB	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	loss	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	CREB	_	NOUN	_	Number=Sing	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	loss	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	functional	_	ADJ	_	Degree=Pos	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	bcl	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	transient	_	ADJ	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	transfection	_	NOUN	_	Number=Sing	_	_	_	_
30	assays	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	presence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	active	_	ADJ	_	Degree=Pos	_	_	_	_
6	CRE	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	bcl	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	implies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	bcl	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	expression	_	NOUN	_	Number=Sing	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	signal	_	ADJ	_	Number=Sing	_	_	_	_
28	transduction	_	NOUN	_	Number=Sing	_	_	_	_
29	pathway	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	B	_	ADJ	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mature	_	ADJ	_	Degree=Pos	_	_	_	_
5	B-	_	NOUN	_	Number=Sing	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	line	_	NOUN	_	Number=Sing	_	_	_	_
8	BAL	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	17	_	NUM	_	NumType=Card	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	either	_	CCONJ	_	_	_	_	_	_
13	anti-immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
14	M	_	NOUN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
17	12	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	myristate	_	NOUN	_	Number=Sing	_	_	_	_
20	13	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	acetate	_	NOUN	_	Number=Sing	_	_	_	_
23	leads	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	increase	_	NOUN	_	Number=Sing	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	bcl	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	that	_	PRON	_	PronType=Rel	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	CRE	_	NOUN	_	Number=Sing	_	_	_	_
38	site	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	more	_	ADV	_	_	_	_	_	_
5	immature	_	ADJ	_	Degree=Pos	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	line	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	Ramos	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	with	_	SCONJ	_	_	_	_	_	_
14	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
15	esters	_	NOUN	_	Number=Plur	_	_	_	_
16	rescues	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	calcium	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	bcl	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	following	_	VERB	_	VerbForm=Ger	_	_	_	_
8	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
9	ester	_	NOUN	_	Number=Sing	_	_	_	_
10	treatment	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	CRE	_	NOUN	_	Number=Sing	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	stimuli	_	ADJ	_	Degree=Pos	_	_	_	_
3	result	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	CREB	_	NOUN	_	Number=Sing	_	_	_	_
8	at	_	ADP	_	_	_	_	_	_
9	serine	_	NOUN	_	Number=Sing	_	_	_	_
10	133	_	NUM	_	NumType=Card	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	CREB	_	PROPN	_	Number=Sing	_	_	_	_
5	that	_	DET	_	PronType=Rel	_	_	_	_
6	results	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	kinase	_	NOUN	_	Number=Sing	_	_	_	_
14	C	_	PROPN	_	Number=Sing	_	_	_	_
15	rather	_	ADV	_	_	_	_	_	_
16	than	_	ADP	_	_	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	protein	_	NOUN	_	Number=Sing	_	_	_	_
19	kinase	_	NOUN	_	Number=Sing	_	_	_	_
20	A	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	CRE	_	NOUN	_	Number=Sing	_	_	_	_
4	site	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	bcl	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	participation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
20	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	element	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	CREB	_	PROPN	_	Number=Sing	_	_	_	_
28	alters	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
30	interaction	_	NOUN	_	Number=Sing	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	upstream	_	ADJ	_	Degree=Pos	_	_	_	_
34	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
35	element	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	CRE	_	NOUN	_	Number=Sing	_	_	_	_
3	site	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	bcl	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	play	_	VERB	_	VerbForm=Inf	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	major	_	ADJ	_	Degree=Pos	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	bcl	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	during	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	mature	_	ADJ	_	Degree=Pos	_	_	_	_
29	B	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	during	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	rescue	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	immature	_	ADJ	_	Degree=Pos	_	_	_	_
37	B	_	NOUN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	from	_	ADP	_	_	_	_	_	_
40	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	possible	_	ADJ	_	Degree=Pos	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	CRE	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	bcl	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	other	_	ADJ	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	types	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	particularly	_	ADV	_	_	_	_	_	_
23	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	which	_	DET	_	PronType=Rel	_	_	_	_
26	protein	_	NOUN	_	Number=Sing	_	_	_	_
27	kinase	_	NOUN	_	Number=Sing	_	_	_	_
28	C	_	PROPN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	involved	_	ADJ	_	Degree=Pos	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012824	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	8	_	NUM	_	NumType=Card	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	tumor	_	NOUN	_	Number=Sing	_	_	_	_
16	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	evidence	_	NOUN	_	Number=Sing	_	_	_	_
21	for	_	ADP	_	_	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
24	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
25	activating	_	NOUN	_	Number=Sing	_	_	_	_
26	pathway	_	NOUN	_	Number=Sing	_	_	_	_
27	distinct	_	NOUN	_	Number=Sing	_	_	_	_
28	from	_	ADP	_	_	_	_	_	_
29	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
30	translocation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Tumor	_	NOUN	_	Number=Sing	_	_	_	_
2	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	pluripotent	_	ADJ	_	Degree=Pos	_	_	_	_
11	activator	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	SCONJ	_	_	_	_	_	_
15	inducing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
19	cascade	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	part	_	ADJ	_	Degree=Pos	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	CXC	_	PROPN	_	Number=Sing	_	_	_	_
15	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	8	_	NUM	_	NumType=Card	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	8	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	investigate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
13	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
14	oxygen	_	NOUN	_	Degree=Pos	_	_	_	_
15	species	_	NOUN	_	Number=Plur	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	ROS	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	8	_	NUM	_	NumType=Card	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	"	_	PUNCT	_	_	_	_	_	_
26	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	like	_	ADP	_	_	_	_	_	_
29	"	_	PUNCT	_	_	_	_	_	_
30	U937	_	PROPN	_	Number=Sing	_	_	_	_
31	histiocytic	_	ADJ	_	Degree=Pos	_	_	_	_
32	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
5	activator	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	8	_	NUM	_	NumType=Card	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	U937	_	PROPN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	50	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	fold	_	NOUN	_	Number=Sing	_	_	_	_
20	induction	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
23	within	_	ADP	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	hour	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	treatment	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	gene	_	NOUN	_	Number=Sing	_	_	_	_
3	transfection	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
10	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	presence	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	Rel	_	ADP	_	_	_	_	_	_
27	A	_	NOUN	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	binding	_	NOUN	_	Number=Sing	_	_	_	_
30	site	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	IL	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	8	_	NUM	_	NumType=Card	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
2	treatment	_	NOUN	_	Number=Sing	_	_	_	_
3	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
6	translocation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	65	_	NUM	_	NumType=Card	_	_	_	_
10	kD	_	NOUN	_	Number=Sing	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	activator	_	NOUN	_	Number=Sing	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	subunit	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	Rel	_	PROPN	_	Number=Sing	_	_	_	_
19	A	_	PROPN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
26	occurs	_	VERB	_	Number=Plur	_	_	_	_
27	before	_	ADP	_	_	_	_	_	_
28	changes	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
31	ROS	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	or	_	CCONJ	_	_	_	_	_	_
4	up	_	ADP	_	_	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	15	_	NUM	_	NumType=Card	_	_	_	_
7	minutes	_	NOUN	_	Number=Plur	_	_	_	_
8	posttreatment	_	NOUN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	relative	_	ADV	_	_	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	antioxidant	_	ADJ	_	Number=Sing	_	_	_	_
16	dimethyl	_	NOUN	_	Number=Sing	_	_	_	_
17	sulfoxide	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	DMSO	_	PROPN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	%	_	SYM	_	Number=Sing	_	_	_	_
24	[	_	PUNCT	_	_	_	_	_	_
25	vol	_	NOUN	_	Number=Sing	_	_	_	_
26	/	_	PUNCT	_	_	_	_	_	_
27	vol	_	NOUN	_	Number=Sing	_	_	_	_
28	]	_	PUNCT	_	_	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	blocks	_	NOUN	_	Number=Plur	_	_	_	_
31	80	_	NUM	_	NumType=Card	_	_	_	_
32	%	_	SYM	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	NF	_	ADJ	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
39	transcription	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Surprisingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	however	_	ADV	_	_	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	DMSO	_	PROPN	_	Number=Sing	_	_	_	_
6	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	no	_	DET	_	_	_	_	_	_
8	effect	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	inducible	_	ADJ	_	Number=Sing	_	_	_	_
11	Rel	_	NOUN	_	Number=Sing	_	_	_	_
12	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	selective	_	ADJ	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	seen	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	unrelated	_	ADJ	_	Degree=Pos	_	_	_	_
14	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	N	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	acetylcysteine	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	NAC	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	vitamin	_	NOUN	_	Number=Sing	_	_	_	_
24	C.	_	PROPN	_	Number=Sing	_	_	_	_
25	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	data	_	NOUN	_	Number=Sing	_	_	_	_
27	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
30	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	delayed	_	ADJ	_	Degree=Pos	_	_	_	_
33	ROS	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
36	signalling	_	NOUN	_	Number=Sing	_	_	_	_
37	pathway	_	NOUN	_	Number=Sing	_	_	_	_
38	that	_	PRON	_	PronType=Rel	_	_	_	_
39	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	NF	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
45	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
46	activation	_	NOUN	_	Number=Sing	_	_	_	_
47	and	_	CCONJ	_	_	_	_	_	_
48	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	separable	_	ADJ	_	Degree=Pos	_	_	_	_
50	from	_	ADP	_	_	_	_	_	_
51	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
52	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
53	for	_	ADP	_	_	_	_	_	_
54	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
55	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
56	translocation	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	definition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	pathway	_	NOUN	_	Number=Sing	_	_	_	_
6	will	_	AUX	_	VerbForm=Fin	_	_	_	_
7	yield	_	VERB	_	VerbForm=Inf	_	_	_	_
8	new	_	ADJ	_	Degree=Pos	_	_	_	_
9	insights	_	NOUN	_	Number=Plur	_	_	_	_
10	into	_	ADP	_	_	_	_	_	_
11	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
12	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	TNFalpha	_	PROPN	_	Number=Sing	_	_	_	_
15	signalling	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012826	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inducible	_	ADJ	_	Degree=Pos	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	elements	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	can	_	AUX	_	VerbForm=Fin	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
24	A	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	signal	_	ADJ	_	Degree=Pos	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
30	manner	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Cyclosporin	_	PROPN	_	Number=Sing	_	_	_	_
2	A	_	PROPN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	CsA	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	exert	_	VERB	_	VerbForm=Inf	_	_	_	_
10	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	immunosuppressive	_	ADJ	_	Degree=Pos	_	_	_	_
12	effects	_	NOUN	_	Number=Plur	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
20	set	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	lymphokine	_	NOUN	_	Number=Sing	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	upon	_	ADP	_	_	_	_	_	_
28	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	among	_	ADP	_	_	_	_	_	_
32	them	_	PRON	_	Case=Acc|Number=Plur|Person=3|PronType=Prs	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	gene	_	NOUN	_	Number=Sing	_	_	_	_
35	coding	_	NOUN	_	Number=Sing	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	partially	_	ADV	_	_	_	_	_	_
16	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	better	_	ADV	_	Degree=Cmp	_	_	_	_
3	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
6	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
7	underlying	_	VERB	_	VerbForm=Ger	_	_	_	_
8	suppression	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	CsA	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	effects	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
19	drug	_	NOUN	_	Number=Sing	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	factors	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	T	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	formation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
10	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
13	DNA	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	complexes	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	complex	_	NOUN	_	Number=Sing	_	_	_	_
22	within	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	HIV	_	PROPN	_	Number=Sing	_	_	_	_
25	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	complex	_	NOUN	_	Number=Sing	_	_	_	_
32	within	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
40	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	presence	_	NOUN	_	Number=Sing	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	CsA	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	kappa	_	NOUN	_	Number=Sing	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	HIV	_	PROPN	_	Number=Sing	_	_	_	_
10	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	only	_	ADV	_	_	_	_	_	_
14	if	_	SCONJ	_	_	_	_	_	_
15	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	via	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	mitogen	_	NOUN	_	Number=Sing	_	_	_	_
21	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
22	whereas	_	SCONJ	_	_	_	_	_	_
23	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
24	myristate	_	NOUN	_	Number=Sing	_	_	_	_
25	acetate	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	completely	_	ADV	_	_	_	_	_	_
31	insensitive	_	ADJ	_	Degree=Pos	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	drug	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	model	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	which	_	PRON	_	PronType=Rel	_	_	_	_
7	functionally	_	ADV	_	_	_	_	_	_
8	indistinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	complexes	_	NOUN	_	Number=Plur	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	via	_	ADP	_	_	_	_	_	_
16	two	_	NUM	_	NumType=Card	_	_	_	_
17	separate	_	ADJ	_	Degree=Pos	_	_	_	_
18	pathways	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	signal	_	ADJ	_	Number=Sing	_	_	_	_
21	transduction	_	NOUN	_	Number=Sing	_	_	_	_
22	distinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	CsA	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012828	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	GrpL	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	Grb2	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	related	_	ADJ	_	Degree=Pos	_	_	_	_
7	adaptor	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	SLP	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	76	_	NUM	_	NumType=Card	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	activation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Propagation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	signals	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	T	_	PROPN	_	Number=Sing	_	_	_	_
7	cell	_	NOUN	_	Number=Sing	_	_	_	_
8	antigen	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	TCR	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	number	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	adaptor	_	NOUN	_	Number=Sing	_	_	_	_
18	molecules	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	SH2	_	PROPN	_	Number=Sing	_	_	_	_
2	domain	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	76	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	SLP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	76	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	guanine	_	NOUN	_	Number=Sing	_	_	_	_
16	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
17	exchange	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	Vav	_	PROPN	_	Number=Sing	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	AT	_	ADP	_	_	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	for	_	ADP	_	_	_	_	_	_
40	normal	_	ADJ	_	Degree=Pos	_	_	_	_
41	T	_	NOUN	_	Number=Sing	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	development	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	cloning	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	characterization	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	novel	_	NOUN	_	Number=Sing	_	_	_	_
10	Grb2	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	like	_	ADJ	_	Degree=Pos	_	_	_	_
13	adaptor	_	NOUN	_	Number=Sing	_	_	_	_
14	molecule	_	NOUN	_	Number=Sing	_	_	_	_
15	designated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	Grb2	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	related	_	ADJ	_	Degree=Pos	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
24	system	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	GrpL	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	GrpL	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	restricted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
8	tissues	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	distinguished	_	ADJ	_	Degree=Pos	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	Grb2	_	PROPN	_	Number=Sing	_	_	_	_
16	by	_	SCONJ	_	_	_	_	_	_
17	having	_	VERB	_	VerbForm=Ger	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	proline	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	rich	_	ADJ	_	Degree=Pos	_	_	_	_
22	region	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	GrpL	_	PROPN	_	Number=Sing	_	_	_	_
2	can	_	AUX	_	VerbForm=Fin	_	_	_	_
3	be	_	AUX	_	VerbForm=Inf	_	_	_	_
4	coimmunoprecipitated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	SLP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	76	_	NUM	_	NumType=Card	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	Sos1	_	NOUN	_	Number=Sing	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	Sos2	_	PROPN	_	Number=Sing	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lysates	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	Grb2	_	PROPN	_	Number=Sing	_	_	_	_
5	can	_	AUX	_	VerbForm=Fin	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	coimmunoprecipitated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	Sos1	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	Sos2	_	PROPN	_	Number=Sing	_	_	_	_
12	but	_	CCONJ	_	_	_	_	_	_
13	not	_	ADV	_	_	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	SLP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	76	_	NUM	_	NumType=Card	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	LAT	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	pp36/38	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	detergent	_	ADJ	_	Degree=Pos	_	_	_	_
11	lysates	_	NOUN	_	Number=Plur	_	_	_	_
12	prepared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
15	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	Grb2	_	PROPN	_	Number=Sing	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	not	_	ADV	_	_	_	_	_	_
23	GrpL	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	presence	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
8	complexes	_	NOUN	_	Number=Plur	_	_	_	_
9	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
10	GrpL	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	Grb2	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	functional	_	ADJ	_	Degree=Pos	_	_	_	_
3	role	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	GrpL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	SLP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	76	_	NUM	_	NumType=Card	_	_	_	_
11	complex	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	ability	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	GrpL	_	PROPN	_	Number=Sing	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	act	_	VERB	_	VerbForm=Inf	_	_	_	_
21	alone	_	ADV	_	_	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	concert	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	SLP	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	76	_	NUM	_	NumType=Card	_	_	_	_
29	to	_	PART	_	_	_	_	_	_
30	augment	_	VERB	_	VerbForm=Inf	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	AT	_	ADP	_	_	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
37	T	_	PROPN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012829	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	initiated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
6	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
9	role	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	early	_	ADJ	_	Degree=Pos	_	_	_	_
12	tissue	_	NOUN	_	Number=Sing	_	_	_	_
13	damage	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	amebic	_	ADJ	_	Degree=Pos	_	_	_	_
16	infection	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	intestine	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	BACKGROUND	_	NOUN	_	Number=Sing	_	_	_	_
2	&	_	CCONJ	_	_	_	_	_	_
3	AIMS	_	NOUN	_	Number=Plur	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_
5	Entamoeba	_	PROPN	_	Number=Sing	_	_	_	_
6	histolytica	_	ADJ	_	Number=Sing	_	_	_	_
7	infection	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	intestine	_	NOUN	_	Number=Sing	_	_	_	_
11	can	_	AUX	_	VerbForm=Fin	_	_	_	_
12	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
13	severe	_	ADJ	_	Degree=Pos	_	_	_	_
14	gut	_	NOUN	_	Number=Sing	_	_	_	_
15	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	aims	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	study	_	NOUN	_	Number=Sing	_	_	_	_
6	were	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	assess	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	role	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	host	_	NOUN	_	Number=Sing	_	_	_	_
14	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	response	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	tissue	_	NOUN	_	Number=Sing	_	_	_	_
19	damage	_	NOUN	_	Number=Sing	_	_	_	_
20	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	amebiasis	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	role	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	intestinal	_	ADJ	_	Degree=Pos	_	_	_	_
29	epithelial	_	NOUN	_	Degree=Pos	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	SCONJ	_	_	_	_	_	_
32	initiating	_	VERB	_	VerbForm=Ger	_	_	_	_
33	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
34	response	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	METHODS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	E.	_	PROPN	_	Number=Sing	_	_	_	_
4	histolytica	_	ADJ	_	Number=Sing	_	_	_	_
5	infection	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	established	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	intestinal	_	ADJ	_	Degree=Pos	_	_	_	_
11	xenografts	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	severe	_	ADJ	_	Degree=Pos	_	_	_	_
14	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	immunodeficient	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	SCID	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	HU	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	INT	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	mice	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	intestinal	_	ADJ	_	Degree=Pos	_	_	_	_
3	epithelial	_	NOUN	_	Degree=Pos	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	responses	_	NOUN	_	Number=Plur	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	amebic	_	ADJ	_	Degree=Pos	_	_	_	_
9	infection	_	NOUN	_	Number=Sing	_	_	_	_
10	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	intraluminal	_	ADJ	_	Degree=Pos	_	_	_	_
15	administration	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	antisense	_	ADJ	_	Degree=Pos	_	_	_	_
19	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	p65	_	NOUN	_	Number=Sing	_	_	_	_
24	subunit	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	role	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	tissue	_	NOUN	_	Number=Sing	_	_	_	_
37	damage	_	NOUN	_	Number=Sing	_	_	_	_
38	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	with	_	ADP	_	_	_	_	_	_
40	amebiasis	_	NOUN	_	Number=Sing	_	_	_	_
41	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
42	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	by	_	SCONJ	_	_	_	_	_	_
44	depleting	_	VERB	_	VerbForm=Ger	_	_	_	_
45	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
46	from	_	ADP	_	_	_	_	_	_
47	SCID	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	HU	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	INT	_	PROPN	_	Number=Sing	_	_	_	_
52	mice	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	RESULTS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Administration	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	antisense	_	ADJ	_	Number=Sing	_	_	_	_
7	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
8	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	production	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	1beta	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
17	8	_	NUM	_	NumType=Card	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	intestinal	_	ADJ	_	Degree=Pos	_	_	_	_
20	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
25	influx	_	NOUN	_	Number=Sing	_	_	_	_
26	into	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	E.	_	PROPN	_	Number=Sing	_	_	_	_
29	histolytica	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	intestinal	_	ADJ	_	Degree=Pos	_	_	_	_
33	xenografts	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	gut	_	NOUN	_	Number=Sing	_	_	_	_
5	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	response	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	antisense	_	ADJ	_	Degree=Pos	_	_	_	_
10	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	depletion	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	SCID	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	HU	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	INT	_	PROPN	_	Number=Sing	_	_	_	_
22	mice	_	NOUN	_	Number=Plur	_	_	_	_
23	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	increase	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	intestinal	_	ADJ	_	Degree=Pos	_	_	_	_
28	permeability	_	NOUN	_	Number=Sing	_	_	_	_
29	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	amebic	_	ADJ	_	Degree=Pos	_	_	_	_
32	infection	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	CONCLUSIONS	_	NOUN	_	Number=Plur	_	_	_	_
2	:	_	PUNCT	_	_	_	_	_	_
3	Intestinal	_	ADJ	_	Degree=Pos	_	_	_	_
4	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	initiate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
9	response	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
15	tissue	_	NOUN	_	Number=Sing	_	_	_	_
16	damage	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	E.	_	PROPN	_	Number=Sing	_	_	_	_
21	histolytica	_	ADJ	_	Number=Sing	_	_	_	_
22	infection	_	NOUN	_	Number=Sing	_	_	_	_
23	;	_	PUNCT	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
26	cascade	_	NOUN	_	Number=Sing	_	_	_	_
27	can	_	AUX	_	VerbForm=Fin	_	_	_	_
28	be	_	AUX	_	VerbForm=Inf	_	_	_	_
29	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	by	_	SCONJ	_	_	_	_	_	_
31	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	genes	_	NOUN	_	Number=Plur	_	_	_	_
36	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	by	_	ADP	_	_	_	_	_	_
38	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
39	factor	_	NOUN	_	Number=Sing	_	_	_	_
40	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012841	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Functional	_	ADJ	_	Degree=Pos	_	_	_	_
2	Myc	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	Max	_	PROPN	_	Number=Sing	_	_	_	_
5	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	hybridomas	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	T	_	NUM	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	hybridomas	_	NOUN	_	Number=Plur	_	_	_	_
4	respond	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	signals	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	SCONJ	_	_	_	_	_	_
9	undergoing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	death	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	this	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	likely	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
20	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
21	events	_	NOUN	_	Number=Plur	_	_	_	_
22	related	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
25	induction	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	immature	_	ADJ	_	Degree=Pos	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	mature	_	ADJ	_	Degree=Pos	_	_	_	_
30	T	_	NOUN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	vivo	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	using	_	VERB	_	VerbForm=Ger	_	_	_	_
4	antisense	_	ADJ	_	Degree=Pos	_	_	_	_
5	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
6	implicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	c	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	Myc	_	PROPN	_	Number=Sing	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	activation	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	c	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	Myc	_	PROPN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	now	_	ADV	_	_	_	_	_	_
11	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	studies	_	NOUN	_	Number=Plur	_	_	_	_
14	using	_	VERB	_	VerbForm=Ger	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
17	negative	_	ADJ	_	Degree=Pos	_	_	_	_
18	form	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	heterodimeric	_	ADJ	_	Degree=Pos	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	partner	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	Max	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
29	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	here	_	ADV	_	PronType=Dem	_	_	_	_
31	inhibits	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	activation	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	coexpression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	reciprocally	_	ADV	_	_	_	_	_	_
7	mutant	_	NOUN	_	Number=Sing	_	_	_	_

1	Myc	_	PROPN	_	Number=Sing	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	capable	_	ADJ	_	Degree=Pos	_	_	_	_
4	of	_	SCONJ	_	_	_	_	_	_
5	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
6	functional	_	ADJ	_	Degree=Pos	_	_	_	_
7	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	mutant	_	NOUN	_	Number=Sing	_	_	_	_
11	Max	_	NOUN	_	Number=Sing	_	_	_	_
12	can	_	AUX	_	VerbForm=Fin	_	_	_	_
13	compensate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
17	negative	_	ADJ	_	Degree=Pos	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	restore	_	VERB	_	VerbForm=Inf	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	imply	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Myc	_	PROPN	_	Number=Sing	_	_	_	_
6	promotes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	obligatory	_	ADJ	_	Degree=Pos	_	_	_	_
13	heterodimerization	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	Max	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	therefore	_	ADV	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	by	_	SCONJ	_	_	_	_	_	_
21	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012842	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	heterodimerization	_	NOUN	_	Number=Sing	_	_	_	_
4	partner	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
7	hormone	_	NOUN	_	Number=Sing	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	Peroxisome	_	ADJ	_	Degree=Pos	_	_	_	_
2	proliferator	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	receptor	_	NOUN	_	Number=Sing	_	_	_	_
6	.	_	PUNCT	_	_	_	_	_	_

1	Retinoid	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	like	_	ADJ	_	Degree=Pos	_	_	_	_
4	receptors	_	NOUN	_	Number=Plur	_	_	_	_
5	play	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	central	_	ADJ	_	Degree=Pos	_	_	_	_
8	role	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	hormonal	_	ADJ	_	Degree=Pos	_	_	_	_
11	responses	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	forming	_	VERB	_	VerbForm=Ger	_	_	_	_
14	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	other	_	ADJ	_	Degree=Pos	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	hormone	_	NOUN	_	Number=Sing	_	_	_	_
19	receptors	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	peroxisome	_	ADJ	_	Degree=Pos	_	_	_	_
9	proliferator	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	receptor	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	PPAR	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	new	_	ADJ	_	Degree=Pos	_	_	_	_
19	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
20	hormone	_	NOUN	_	Number=Sing	_	_	_	_
21	receptor	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	THR	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	auxiliary	_	ADJ	_	Degree=Pos	_	_	_	_
26	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	heterodimerizing	_	VERB	_	Number=Sing	_	_	_	_
30	with	_	ADP	_	_	_	_	_	_
31	THR	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	solution	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
4	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	recognize	_	VERB	_	VerbForm=Inf	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	classical	_	ADJ	_	Degree=Pos	_	_	_	_
9	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
10	hormone	_	NOUN	_	Number=Sing	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	TRE	_	X	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	direct	_	ADJ	_	Degree=Pos	_	_	_	_
19	repeat	_	NOUN	_	Number=Sing	_	_	_	_
20	separated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	four	_	NUM	_	NumType=Card	_	_	_	_
23	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	DR+4	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	PPAR	_	NOUN	_	Number=Sing	_	_	_	_
29	behaves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
33	negative	_	ADJ	_	Degree=Pos	_	_	_	_
34	regulator	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
37	hormone	_	NOUN	_	Number=Sing	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	TH	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	action	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	TH	_	NOUN	_	_	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
7	positive	_	ADJ	_	Degree=Pos	_	_	_	_
8	effect	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	elicited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	selective	_	ADJ	_	Degree=Pos	_	_	_	_
13	interaction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	THR	_	NOUN	_	Number=Sing	_	_	_	_
17	beta-PPAR	_	NOUN	_	Number=Sing	_	_	_	_
18	but	_	CCONJ	_	_	_	_	_	_
19	not	_	ADV	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	THR	_	NOUN	_	Number=Sing	_	_	_	_
22	alpha-PPAR	_	NOUN	_	Number=Sing	_	_	_	_
23	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	novel	_	NOUN	_	Number=Sing	_	_	_	_
27	TRE	_	PROPN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	DR	_	NOUN	_	Number=Sing	_	_	_	_
30	+	_	SYM	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	critical	_	ADJ	_	Degree=Pos	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	THR	_	NOUN	_	Number=Sing	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	mapped	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	3	_	NUM	_	NumType=Card	_	_	_	_
11	amino	_	ADJ	_	Degree=Pos	_	_	_	_
12	acids	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	distal	_	NOUN	_	Number=Sing	_	_	_	_
16	box	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	DNA	_	PROPN	_	Number=Sing	_	_	_	_
20	binding	_	VERB	_	Number=Sing	_	_	_	_
21	domain	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Hence	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	PPAR	_	PROPN	_	Number=Sing	_	_	_	_
4	can	_	AUX	_	VerbForm=Fin	_	_	_	_
5	positively	_	ADV	_	_	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	negatively	_	ADV	_	_	_	_	_	_
8	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
9	TH	_	DET	_	_	_	_	_	_
10	action	_	NOUN	_	Number=Sing	_	_	_	_
11	depending	_	VERB	_	VerbForm=Ger	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	TRE	_	NOUN	_	Number=Sing	_	_	_	_
14	structure	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	THR	_	NOUN	_	Number=Sing	_	_	_	_
17	isotype	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012845	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Purification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	TCF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	C	_	PROPN	_	Number=Sing	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	context	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	manner	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	into	_	ADP	_	_	_	_	_	_
7	functionally	_	ADV	_	_	_	_	_	_
8	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
9	subpopulations	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	part	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	silencing	_	NOUN	_	Number=Sing	_	_	_	_
20	;	_	PUNCT	_	_	_	_	_	_
21	however	_	ADV	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	little	_	ADV	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	detail	_	NOUN	_	Number=Sing	_	_	_	_
28	about	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	that	_	PRON	_	PronType=Rel	_	_	_	_
32	influence	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
34	developmental	_	ADJ	_	Degree=Pos	_	_	_	_
35	process	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	new	_	ADJ	_	Degree=Pos	_	_	_	_
6	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	TCF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	alpha	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	genes	_	NOUN	_	Number=Plur	_	_	_	_
24	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	major	_	ADJ	_	Degree=Pos	_	_	_	_
27	component	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
32	receptor	_	NOUN	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	TCR	_	NOUN	_	Number=Sing	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	TCF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	alpha	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	originally	_	ADV	_	_	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	through	_	ADP	_	_	_	_	_	_
11	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	binding	_	NOUN	_	Degree=Pos	_	_	_	_
13	sites	_	NOUN	_	Number=Plur	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	TCR	_	PROPN	_	Number=Sing	_	_	_	_
28	alpha	_	NOUN	_	Number=Sing	_	_	_	_
29	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	promoters	_	NOUN	_	Number=Plur	_	_	_	_
33	for	_	ADP	_	_	_	_	_	_
34	several	_	ADJ	_	Degree=Pos	_	_	_	_
35	genes	_	NOUN	_	Number=Plur	_	_	_	_
36	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	at	_	ADP	_	_	_	_	_	_
38	significantly	_	ADV	_	_	_	_	_	_
39	earlier	_	ADJ	_	Degree=Cmp	_	_	_	_
40	stages	_	NOUN	_	Number=Plur	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
43	development	_	NOUN	_	Number=Sing	_	_	_	_
44	than	_	ADP	_	_	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	TCR	_	NOUN	_	Number=Sing	_	_	_	_
47	alpha	_	NOUN	_	Number=Sing	_	_	_	_
48	gene	_	NOUN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	e.g.	_	X	_	_	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	p56lck	_	NOUN	_	Number=Sing	_	_	_	_
53	and	_	CCONJ	_	_	_	_	_	_
54	CD3	_	PROPN	_	Number=Sing	_	_	_	_
55	delta	_	PROPN	_	Number=Sing	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Sequences	_	NOUN	_	Number=Plur	_	_	_	_
2	related	_	ADJ	_	Degree=Pos	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	TCF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	motif	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	5'-	_	NUM	_	_	_	_	_	_
13	GGCACCCTTTGA	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	3	_	NUM	_	NumType=Card	_	_	_	_
16	'	_	PUNCT	_	_	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	TCR	_	NOUN	_	Number=Sing	_	_	_	_
25	delta	_	PROPN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	possibly	_	ADV	_	_	_	_	_	_
29	TCR	_	NOUN	_	Number=Sing	_	_	_	_
30	beta	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Southwestern	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	gel	_	NOUN	_	Number=Sing	_	_	_	_
4	renaturation	_	NOUN	_	Number=Sing	_	_	_	_
5	experiments	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	use	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	fractions	_	NOUN	_	Number=Plur	_	_	_	_
13	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	TCF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	derived	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	from	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	family	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	57	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	53	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	SYM	_	_	_	_	_	_
31	kD	_	NOUN	_	Number=Sing	_	_	_	_
32	proteins	_	NOUN	_	Number=Plur	_	_	_	_
33	that	_	PRON	_	PronType=Rel	_	_	_	_
34	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	abundantly	_	ADV	_	_	_	_	_	_
36	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	mature	_	ADJ	_	Degree=Pos	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	immature	_	ADJ	_	Degree=Pos	_	_	_	_
41	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
42	lines	_	NOUN	_	Number=Plur	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	CCRF	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	CEM	_	NOUN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	not	_	PART	_	_	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	mature	_	ADJ	_	Degree=Pos	_	_	_	_
54	B	_	NOUN	_	Number=Sing	_	_	_	_
55	cells	_	NOUN	_	Number=Plur	_	_	_	_
56	(	_	PUNCT	_	_	_	_	_	_
57	JY	_	PROPN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	Namalwa	_	PROPN	_	Number=Sing	_	_	_	_
60	)	_	PUNCT	_	_	_	_	_	_
61	or	_	CCONJ	_	_	_	_	_	_
62	nonlymphoid	_	NOUN	_	Number=Sing	_	_	_	_
63	(	_	PUNCT	_	_	_	_	_	_
64	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
65	)	_	PUNCT	_	_	_	_	_	_
66	cell	_	NOUN	_	Number=Sing	_	_	_	_
67	lines	_	NOUN	_	Number=Plur	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	small	_	ADJ	_	Degree=Pos	_	_	_	_
3	95	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	bp	_	NOUN	_	Number=Sing	_	_	_	_
6	fragment	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	TCR	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	control	_	NOUN	_	Number=Sing	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	TCF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	juxtaposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	between	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	response	_	NOUN	_	Number=Sing	_	_	_	_
28	element	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	CRE	_	PROPN	_	Number=Sing	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	T	_	PROPN	_	Number=Sing	_	_	_	_
34	alpha	_	NOUN	_	Number=Sing	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	motif	_	NOUN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	binding	_	NOUN	_	Number=Sing	_	_	_	_
41	site	_	NOUN	_	Number=Sing	_	_	_	_
42	for	_	ADP	_	_	_	_	_	_
43	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
44	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
45	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	specific	_	ADJ	_	Degree=Pos	_	_	_	_
48	protein	_	NOUN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	TCF	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	2	_	NUM	_	NumType=Card	_	_	_	_
53	alpha	_	NOUN	_	Number=Sing	_	_	_	_
54	)	_	PUNCT	_	_	_	_	_	_
55	behaved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
56	as	_	ADP	_	_	_	_	_	_
57	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
58	potent	_	ADJ	_	Degree=Pos	_	_	_	_
59	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	specific	_	ADJ	_	Degree=Pos	_	_	_	_
62	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
63	in	_	ADP	_	_	_	_	_	_
64	vivo	_	NOUN	_	Number=Sing	_	_	_	_
65	.	_	PUNCT	_	_	_	_	_	_

1	Tandem	_	NOUN	_	Number=Sing	_	_	_	_
2	copies	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
6	functioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	synergistically	_	ADV	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	mature	_	ADJ	_	Degree=Pos	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	lines	_	NOUN	_	Number=Plur	_	_	_	_
17	as	_	ADV	_	_	_	_	_	_
18	well	_	ADV	_	Degree=Pos	_	_	_	_
19	as	_	SCONJ	_	_	_	_	_	_
20	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	immature	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	CCRF	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	CEM	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_

1	T	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	TCF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	diminished	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	disrupted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	synergism	_	NOUN	_	Number=Sing	_	_	_	_
17	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	vivo	_	NOUN	_	Number=Sing	_	_	_	_
20	between	_	ADP	_	_	_	_	_	_
21	tandem	_	NOUN	_	Number=Sing	_	_	_	_
22	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
23	repeats	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	TCF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	TCR	_	NOUN	_	Number=Sing	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	transcriptionally	_	ADV	_	_	_	_	_	_
18	active	_	ADJ	_	Degree=Pos	_	_	_	_
19	extracts	_	NOUN	_	Number=Plur	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	not	_	ADV	_	_	_	_	_	_
24	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	confirming	_	VERB	_	VerbForm=Ger	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	TCF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	alpha	_	NOUN	_	Number=Sing	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	specific	_	ADJ	_	Degree=Pos	_	_	_	_
38	transcription	_	NOUN	_	Number=Sing	_	_	_	_
39	factor	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Curiously	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	TCF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	element	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vivo	_	NOUN	_	Number=Sing	_	_	_	_
14	when	_	ADV	_	PronType=Int	_	_	_	_
15	removed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	from	_	ADP	_	_	_	_	_	_
17	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	neighboring	_	VERB	_	VerbForm=Ger	_	_	_	_
19	elements	_	NOUN	_	Number=Plur	_	_	_	_
20	on	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	TCR	_	PROPN	_	Number=Sing	_	_	_	_
23	alpha	_	NOUN	_	Number=Sing	_	_	_	_
24	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	positioned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	one	_	NUM	_	NumType=Card	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	more	_	ADJ	_	Degree=Cmp	_	_	_	_
31	copies	_	NOUN	_	Number=Plur	_	_	_	_
32	upstream	_	ADV	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
35	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	TCF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	depend	_	VERB	_	VerbForm=Inf	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	TCF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	T	_	PROPN	_	Number=Sing	_	_	_	_
22	alpha	_	NOUN	_	Number=Sing	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	CREB	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	factors	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	context	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
34	binding	_	NOUN	_	Number=Sing	_	_	_	_
35	site	_	NOUN	_	Number=Sing	_	_	_	_
36	within	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	TCR	_	NOUN	_	Number=Sing	_	_	_	_
39	alpha	_	NOUN	_	Number=Sing	_	_	_	_
40	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012850	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CIITA	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	modification	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	vivo	_	PROPN	_	Number=Sing	_	_	_	_
9	HLA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	DR	_	PROPN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	occupancy	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	normal	_	ADJ	_	Degree=Pos	_	_	_	_
16	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
17	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	IFN	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	gamma	_	NOUN	_	Number=Sing	_	_	_	_
24	:	_	PUNCT	_	_	_	_	_	_
25	similarities	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	distinctions	_	NOUN	_	Number=Plur	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	respect	_	NOUN	_	Number=Sing	_	_	_	_
30	to	_	ADP	_	_	_	_	_	_
31	HLA	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	DR	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	MHC	_	PROPN	_	Number=Sing	_	_	_	_
12	class	_	NOUN	_	Number=Sing	_	_	_	_
13	II	_	NUM	_	NumType=Card	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	primary	_	ADJ	_	Degree=Pos	_	_	_	_
18	cultures	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	thymic	_	ADJ	_	Degree=Pos	_	_	_	_
21	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	TEC	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
27	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
3	system	_	NOUN	_	Number=Sing	_	_	_	_
4	offers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	advantage	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	MHC	_	PROPN	_	Number=Sing	_	_	_	_
9	class	_	NOUN	_	Number=Sing	_	_	_	_
10	II	_	NUM	_	Number=Sing	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	"	_	PUNCT	_	_	_	_	_	_
17	physiologic	_	ADJ	_	Degree=Pos	_	_	_	_
18	"	_	PUNCT	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	lineage	_	NOUN	_	Number=Sing	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	result	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	within	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	thymus	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	selection	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	maturation	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	T	_	NOUN	_	Number=Sing	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	MHC	_	PROPN	_	Number=Sing	_	_	_	_
7	class	_	NOUN	_	Number=Sing	_	_	_	_
8	II	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	de	_	X	_	Number=Sing	_	_	_	_
16	novo	_	NOUN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
24	trans	_	NOUN	_	Number=Plur	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	activator	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
30	MHC	_	PROPN	_	Number=Sing	_	_	_	_
31	class	_	NOUN	_	Number=Sing	_	_	_	_
32	II	_	NUM	_	NumType=Card	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	anatomy	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	interaction	_	NOUN	_	Number=Sing	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	MHC	_	PROPN	_	Number=Sing	_	_	_	_
10	class	_	NOUN	_	Number=Sing	_	_	_	_
11	II	_	NUM	_	NumType=Card	_	_	_	_
12	DRA	_	NOUN	_	Number=Sing	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	corresponding	_	VERB	_	VerbForm=Ger	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	vivo	_	PROPN	_	Number=Sing	_	_	_	_
23	DNAse	_	PROPN	_	Number=Sing	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	footprint	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	DET	_	_	_	_	_	_
5	treatment	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	gamma	_	NOUN	_	Number=Sing	_	_	_	_
10	induces	_	VERB	_	Number=Plur	_	_	_	_
11	changes	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	occupancy	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	DRA	_	PROPN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
20	sequences	_	NOUN	_	Number=Plur	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
3	occupancy	_	NOUN	_	Number=Sing	_	_	_	_
4	displays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	strong	_	ADJ	_	Degree=Pos	_	_	_	_
6	similarities	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	one	_	NOUN	_	NumType=Card	_	_	_	_
10	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	MHC	_	PROPN	_	Number=Sing	_	_	_	_
14	class	_	NOUN	_	Number=Sing	_	_	_	_
15	II	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	represented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	both	_	CCONJ	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	Burkitt	_	PROPN	_	Number=Sing	_	_	_	_
26	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
27	line	_	NOUN	_	Number=Sing	_	_	_	_
28	Raji	_	PROPN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	normal	_	ADJ	_	Degree=Pos	_	_	_	_
31	tonsil	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	some	_	DET	_	_	_	_	_	_
4	peculiar	_	ADJ	_	Degree=Pos	_	_	_	_
5	differences	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	between	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	TEC	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	either	_	CCONJ	_	_	_	_	_	_
13	IFN	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	gamma	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	both	_	DET	_	_	_	_	_	_
6	common	_	ADJ	_	Degree=Pos	_	_	_	_
7	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	such	_	ADJ	_	Degree=Pos	_	_	_	_
10	as	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	one	_	NOUN	_	NumType=Card	_	_	_	_
13	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	CIITA	_	PROPN	_	Number=Sing	_	_	_	_
17	trans	_	NOUN	_	Number=Plur	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	activator	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
23	tissue	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	constraints	_	NOUN	_	Number=Plur	_	_	_	_
27	contribute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
31	control	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	IFN	_	ADJ	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	gamma	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	MHC	_	PROPN	_	Number=Sing	_	_	_	_
41	class	_	NOUN	_	Number=Sing	_	_	_	_
42	II	_	NUM	_	NumType=Card	_	_	_	_
43	gene	_	NOUN	_	Number=Sing	_	_	_	_
44	expression	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012854	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
4	repression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	arteritis	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	SCID	_	ADJ	_	Number=Sing	_	_	_	_
14	chimeras	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Giant	_	ADJ	_	Degree=Pos	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	arteritis	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	GCA	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	vasculitic	_	ADJ	_	Degree=Pos	_	_	_	_
10	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	PRON	_	PronType=Rel	_	_	_	_
12	preferentially	_	ADV	_	_	_	_	_	_
13	affects	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	medium	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	large	_	ADJ	_	Degree=Pos	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	sized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	arteries	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
2	therapy	_	NOUN	_	Number=Sing	_	_	_	_
3	resolves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
5	symptoms	_	NOUN	_	Number=Plur	_	_	_	_
6	within	_	ADP	_	_	_	_	_	_
7	hours	_	NOUN	_	Number=Plur	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	days	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	therapy	_	NOUN	_	Number=Sing	_	_	_	_
13	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	continued	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	over	_	ADP	_	_	_	_	_	_
18	several	_	ADJ	_	Degree=Pos	_	_	_	_
19	years	_	NOUN	_	Number=Plur	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
22	disease	_	NOUN	_	Number=Sing	_	_	_	_
23	relapses	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	whether	_	SCONJ	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	how	_	ADV	_	PronType=Int	_	_	_	_
8	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
9	affect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	function	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	infiltrate	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	why	_	ADV	_	PronType=Int	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	disease	_	NOUN	_	Number=Sing	_	_	_	_
20	persists	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	subclinically	_	ADV	_	_	_	_	_	_
22	despite	_	ADP	_	_	_	_	_	_
23	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
24	treatment	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	GCA	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	self	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	temporal	_	ADJ	_	Degree=Pos	_	_	_	_
8	arteries	_	NOUN	_	Number=Plur	_	_	_	_
9	engrafted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	into	_	ADP	_	_	_	_	_	_
11	SCID	_	PROPN	_	Number=Sing	_	_	_	_
12	mice	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	providing	_	VERB	_	VerbForm=Ger	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	model	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	which	_	PRON	_	PronType=Rel	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	action	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	limitations	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
27	therapy	_	NOUN	_	Number=Sing	_	_	_	_
28	can	_	AUX	_	VerbForm=Fin	_	_	_	_
29	be	_	AUX	_	VerbForm=Inf	_	_	_	_
30	examined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	vivo	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Administration	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	temporal	_	ADJ	_	Degree=Pos	_	_	_	_
6	artery	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	SCID	_	ADJ	_	Number=Sing	_	_	_	_
9	chimeras	_	NOUN	_	Number=Plur	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	wk	_	NOUN	_	Number=Sing	_	_	_	_
13	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	partial	_	ADJ	_	Degree=Pos	_	_	_	_
16	suppression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
22	function	_	NOUN	_	Number=Sing	_	_	_	_
23	as	_	SCONJ	_	_	_	_	_	_
24	indicated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	tissue	_	NOUN	_	Number=Sing	_	_	_	_
29	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	IL	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	IL	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1beta	_	PROPN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	6	_	NUM	_	NumType=Card	_	_	_	_
43	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	by	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	diminished	_	ADJ	_	Degree=Pos	_	_	_	_
49	expression	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	inducible	_	ADJ	_	Number=Sing	_	_	_	_
52	NO	_	DET	_	_	_	_	_	_
53	synthase	_	NOUN	_	Number=Sing	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	only	_	ADV	_	_	_	_	_	_
12	slightly	_	ADV	_	_	_	_	_	_
13	decreased	_	VERB	_	Degree=Pos	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	TGF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	beta1	_	NOUN	_	Number=Sing	_	_	_	_
21	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
22	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	correlated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	blockade	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	translocation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	xenotransplanted	_	VERB	_	Degree=Pos	_	_	_	_
21	tissue	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Dose	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	response	_	NOUN	_	Number=Sing	_	_	_	_
4	experiments	_	NOUN	_	Number=Plur	_	_	_	_
5	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	steroid	_	NOUN	_	Number=Sing	_	_	_	_
8	doses	_	NOUN	_	Number=Plur	_	_	_	_
9	currently	_	ADV	_	_	_	_	_	_
10	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
13	medicine	_	NOUN	_	Number=Sing	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	suboptimal	_	ADJ	_	Degree=Pos	_	_	_	_
16	in	_	SCONJ	_	_	_	_	_	_
17	repressing	_	VERB	_	VerbForm=Ger	_	_	_	_
18	NFkappaB	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
21	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
22	production	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
26	lesions	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Chronic	_	ADJ	_	Degree=Pos	_	_	_	_
2	steroid	_	NOUN	_	Number=Sing	_	_	_	_
3	therapy	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	able	_	ADJ	_	Degree=Pos	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	deplete	_	VERB	_	VerbForm=Inf	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	products	_	NOUN	_	Number=Plur	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IFN	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	gamma	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	whereas	_	SCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	tissue	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	infiltrating	_	VERB	_	VerbForm=Ger	_	_	_	_
27	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
28	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
29	only	_	ADV	_	_	_	_	_	_
30	partially	_	ADV	_	_	_	_	_	_
31	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1beta	_	PROPN	_	Number=Sing	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	abrogated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	;	_	PUNCT	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	contrast	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	TGF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	beta1	_	NOUN	_	Number=Sing	_	_	_	_
14	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
15	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	steroid	_	NOUN	_	Degree=Pos	_	_	_	_
18	resistant	_	ADJ	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	persistence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	TGF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	beta1	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	transcribing	_	VERB	_	Number=Sing	_	_	_	_
9	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	despite	_	ADP	_	_	_	_	_	_
12	paralysis	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	T	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	function	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	may	_	AUX	_	VerbForm=Fin	_	_	_	_
19	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	explanation	_	NOUN	_	Number=Sing	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	chronicity	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	disease	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	may	_	AUX	_	VerbForm=Fin	_	_	_	_
31	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	novel	_	NOUN	_	Number=Sing	_	_	_	_
34	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
35	target	_	NOUN	_	Number=Sing	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
38	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
39	vasculopathy	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012875	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	vacuolar	_	NOUN	_	Degree=Pos	_	_	_	_
6	H	_	NOUN	_	Number=Sing	_	_	_	_
7	(+)-	_	PUNCT	_	_	_	_	_	_
8	ATPase	_	NOUN	_	Number=Sing	_	_	_	_

1	B2	_	ADP	_	Number=Sing	_	_	_	_
2	subunit	_	NOUN	_	Number=Sing	_	_	_	_
3	gene	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	SCONJ	_	_	_	_	_	_
5	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
6	THP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Monocyte	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
4	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	model	_	NOUN	_	Number=Sing	_	_	_	_
10	system	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	SCONJ	_	_	_	_	_	_
12	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	vacuolar	_	NOUN	_	Number=Sing	_	_	_	_
19	H	_	NOUN	_	Number=Sing	_	_	_	_
20	(+	_	SYM	_	_	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	ATPase	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	V	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	ATPase	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
4	levels	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	various	_	ADJ	_	Degree=Pos	_	_	_	_
7	V	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	ATPase	_	NOUN	_	Number=Sing	_	_	_	_
10	subunits	_	NOUN	_	Number=Plur	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	both	_	DET	_	_	_	_	_	_
15	native	_	ADJ	_	Degree=Pos	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	line	_	NOUN	_	Number=Sing	_	_	_	_
21	THP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	post	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
33	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
34	could	_	AUX	_	VerbForm=Fin	_	_	_	_
35	account	_	VERB	_	VerbForm=Inf	_	_	_	_
36	for	_	ADP	_	_	_	_	_	_
37	increases	_	NOUN	_	Number=Plur	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	cell	_	NOUN	_	Number=Sing	_	_	_	_
40	V	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	AT	_	ADP	_	_	_	_	_	_
43	Pase	_	NOUN	_	Number=Sing	_	_	_	_
44	content	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	From	_	ADP	_	_	_	_	_	_
2	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
3	runoff	_	NOUN	_	Number=Sing	_	_	_	_
4	experiments	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	one	_	NUM	_	NumType=Card	_	_	_	_
10	subunit	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	particular	_	ADJ	_	Degree=Pos	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	B2	_	PROPN	_	Number=Sing	_	_	_	_
16	isoform	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	Mr	_	PROPN	_	Number=Sing	_	_	_	_
19	=	_	SYM	_	_	_	_	_	_
20	56,000	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	amplified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	primarily	_	ADV	_	_	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
28	means	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	begun	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	structure	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	B2	_	PROPN	_	Number=Sing	_	_	_	_
11	subunit	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	region	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Isolation	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	sequencing	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	exon	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	5	_	NUM	_	NumType=Card	_	_	_	_
10	'-	_	PUNCT	_	_	_	_	_	_
11	flanking	_	VERB	_	Number=Sing	_	_	_	_
12	region	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	TATA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	less	_	ADJ	_	Degree=Cmp	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	high	_	ADJ	_	Degree=Pos	_	_	_	_
25	G	_	NOUN	_	Number=Sing	_	_	_	_
26	+	_	SYM	_	_	_	_	_	_
27	C	_	NOUN	_	Number=Sing	_	_	_	_
28	content	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Primer	_	ADJ	_	Number=Sing	_	_	_	_
2	extension	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	ribonuclease	_	NOUN	_	Number=Sing	_	_	_	_
5	protection	_	NOUN	_	Number=Sing	_	_	_	_
6	analyses	_	NOUN	_	Number=Plur	_	_	_	_
7	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	single	_	ADJ	_	Degree=Pos	_	_	_	_
10	major	_	ADJ	_	Degree=Pos	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	start	_	NOUN	_	Number=Sing	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	transfected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
6	reporter	_	NOUN	_	Number=Sing	_	_	_	_
7	plasmids	_	NOUN	_	Number=Plur	_	_	_	_
8	into	_	ADP	_	_	_	_	_	_
9	THP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	define	_	VERB	_	VerbForm=Inf	_	_	_	_
15	sequences	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	mediate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
19	control	_	NOUN	_	Number=Sing	_	_	_	_
20	during	_	ADP	_	_	_	_	_	_
21	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	sequences	_	NOUN	_	Number=Plur	_	_	_	_
5	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	start	_	NOUN	_	Number=Sing	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	confer	_	VERB	_	VerbForm=Inf	_	_	_	_
15	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	THP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	DNase	_	NOUN	_	Number=Sing	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	footprinting	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	sequence	_	NOUN	_	Number=Sing	_	_	_	_
6	analysis	_	NOUN	_	Number=Sing	_	_	_	_
7	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	existence	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
12	AP2	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	5'-	_	NUM	_	Number=Sing	_	_	_	_
20	untranslated	_	ADJ	_	Degree=Pos	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
23	coding	_	NOUN	_	Number=Sing	_	_	_	_
24	regions	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012882	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	fas	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	ligand	_	NOUN	_	Degree=Pos	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	during	_	ADP	_	_	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	death	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	via	_	ADP	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	engagement	_	NOUN	_	Number=Sing	_	_	_	_
5	activates	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	important	_	ADJ	_	Degree=Pos	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	signaling	_	NOUN	_	Number=Sing	_	_	_	_
5	pathway	_	NOUN	_	Number=Sing	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	FasL	_	NOUN	_	Degree=Pos	_	_	_	_
21	transcription	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	involved	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
20	regulation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	many	_	ADJ	_	Degree=Pos	_	_	_	_
23	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
24	genes	_	NOUN	_	Number=Plur	_	_	_	_
25	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	also	_	ADV	_	_	_	_	_	_
31	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	role	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	T	_	PROPN	_	Number=Sing	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	FasL	_	ADJ	_	Number=Sing	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	T	_	NUM	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	hybridoma	_	NOUN	_	Number=Sing	_	_	_	_
12	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	FasL	_	ADJ	_	Degree=Pos	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
19	upon	_	ADP	_	_	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	receptor	_	NOUN	_	Number=Sing	_	_	_	_
23	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	FasL	_	NOUN	_	Number=Sing	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	contributes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	such	_	ADJ	_	Degree=Pos	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Co-	_	PUNCT	_	_	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p65	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	Rel	_	NOUN	_	Number=Sing	_	_	_	_
7	A	_	X	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	FasL	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	co-expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	IkappaB	_	PROPN	_	Number=Sing	_	_	_	_
21	dramatically	_	ADV	_	_	_	_	_	_
22	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	activity	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	AP	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	not	_	PART	_	_	_	_	_	_
12	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	FasL	_	NOUN	_	Number=Sing	_	_	_	_
18	promoter	_	NOUN	_	Number=Sing	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	define	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	SCONJ	_	_	_	_	_	_
11	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	FasL	_	ADJ	_	Degree=Pos	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	during	_	ADP	_	_	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012887	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	c	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	jun	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	jun	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	jun	_	NOUN	_	Number=Sing	_	_	_	_
11	D	_	PROPN	_	Number=Sing	_	_	_	_
12	proto	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	peripheral	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	blood	_	NOUN	_	Number=Sing	_	_	_	_
20	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	peripheral	_	NOUN	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	blood	_	NOUN	_	Number=Sing	_	_	_	_
10	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	express	_	VERB	_	Degree=Pos	_	_	_	_
12	constitutively	_	ADV	_	_	_	_	_	_
13	significant	_	ADJ	_	Degree=Pos	_	_	_	_
14	levels	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	proto	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	oncogenes	_	NOUN	_	Number=Sing	_	_	_	_
19	c	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	jun	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	jun	_	PROPN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	jun	_	PROPN	_	Number=Sing	_	_	_	_
27	D	_	NOUN	_	Number=Sing	_	_	_	_
28	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Upon	_	ADP	_	_	_	_	_	_
2	functional	_	ADJ	_	Degree=Pos	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	4	_	NUM	_	NumType=Card	_	_	_	_
8	beta-phorbol	_	NOUN	_	Number=Sing	_	_	_	_
9	12	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	myristate	_	NOUN	_	Number=Sing	_	_	_	_
12	13	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	acetate	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	PMA	_	PROPN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	levels	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	c	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	jun	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	jun	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	jun	_	NOUN	_	Number=Sing	_	_	_	_
30	D	_	NOUN	_	Number=Sing	_	_	_	_
31	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
32	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
33	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	three	_	NUM	_	NumType=Card	_	_	_	_
3	jun	_	NOUN	_	Number=Sing	_	_	_	_
4	genes	_	NOUN	_	Number=Plur	_	_	_	_
5	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	similar	_	ADJ	_	Degree=Pos	_	_	_	_
8	time	_	NOUN	_	Number=Sing	_	_	_	_
9	course	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	PMA	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
17	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
18	levels	_	NOUN	_	Number=Plur	_	_	_	_
19	being	_	AUX	_	VerbForm=Ger	_	_	_	_
20	reached	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	after	_	ADP	_	_	_	_	_	_
22	60	_	NUM	_	NumType=Card	_	_	_	_
23	min	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	induction	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	Number=Sing|PronType=Dem	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	c	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	jun	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	jun	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	jun	_	PROPN	_	Number=Sing	_	_	_	_
15	D	_	PROPN	_	Number=Sing	_	_	_	_
16	genes	_	NOUN	_	Number=Plur	_	_	_	_
17	might	_	AUX	_	VerbForm=Fin	_	_	_	_
18	be	_	AUX	_	VerbForm=Inf	_	_	_	_
19	involved	_	ADJ	_	Degree=Pos	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
22	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	in	_	SCONJ	_	_	_	_	_	_
26	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
27	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
28	functionality	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012888	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Oxidants	_	NOUN	_	Number=Plur	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	intestinal	_	ADJ	_	Degree=Pos	_	_	_	_
8	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	now	_	ADV	_	_	_	_	_	_
4	well	_	ADV	_	Degree=Pos	_	_	_	_
5	appreciated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	chronic	_	ADJ	_	Degree=Pos	_	_	_	_
8	gut	_	NOUN	_	Number=Sing	_	_	_	_
9	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
17	metabolites	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	nitrogen	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Some	_	DET	_	_	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	oxidants	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	variety	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	involved	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	immune	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	responses	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	example	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	certain	_	ADJ	_	Degree=Pos	_	_	_	_
5	oxidants	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	which	_	PRON	_	PronType=Rel	_	_	_	_
18	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	variety	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	different	_	ADJ	_	Degree=Pos	_	_	_	_
26	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
27	molecules	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	enzymes	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Oxidants	_	NOUN	_	Number=Plur	_	_	_	_
2	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	another	_	DET	_	_	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	activator	_	NOUN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	products	_	NOUN	_	Number=Plur	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	fos	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	jun	_	NOUN	_	Number=Sing	_	_	_	_
13	proto	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
16	family	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	important	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	SCONJ	_	_	_	_	_	_
24	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	growth	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	oxidants	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
8	intestinal	_	ADJ	_	Degree=Pos	_	_	_	_
9	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
19	/	_	PUNCT	_	_	_	_	_	_
20	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	product	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	believed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
29	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
30	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	antioxidant	_	ADJ	_	Degree=Pos	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
36	manner	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	observations	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	nontoxic	_	ADJ	_	Degree=Pos	_	_	_	_
9	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
12	metabolites	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	nitrogen	_	NOUN	_	Number=Sing	_	_	_	_
17	play	_	VERB	_	VerbForm=Inf	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	important	_	ADJ	_	Degree=Pos	_	_	_	_
20	role	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	SCONJ	_	_	_	_	_	_
22	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	genes	_	NOUN	_	Number=Plur	_	_	_	_
27	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	response	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	modulating	_	VERB	_	Number=Sing	_	_	_	_
35	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012895	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	tumor	_	NOUN	_	Number=Sing	_	_	_	_
3	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
10	ester	_	NOUN	_	Number=Sing	_	_	_	_
11	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	lines	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	minimal	_	ADJ	_	Degree=Pos	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	tumor	_	NOUN	_	Number=Sing	_	_	_	_
8	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
9	factor	_	NOUN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	alpha	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	induction	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
25	esters	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	PMA	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	B	_	ADJ	_	Degree=Pos	_	_	_	_
34	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
35	cell	_	NOUN	_	Number=Sing	_	_	_	_
36	lines	_	NOUN	_	Number=Plur	_	_	_	_
37	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
39	localized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	between	_	ADP	_	_	_	_	_	_
41	-	_	SYM	_	_	_	_	_	_
42	52	_	NUM	_	NumType=Card	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	+89	_	NUM	_	NumType=Card	_	_	_	_
45	nucleotides	_	NOUN	_	Number=Plur	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	nt	_	X	_	_	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	relative	_	ADV	_	_	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	gene	_	NOUN	_	Number=Sing	_	_	_	_
53	's	_	PART	_	_	_	_	_	_
54	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
55	start	_	NOUN	_	Number=Sing	_	_	_	_
56	site	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Comparison	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	sequences	_	NOUN	_	Number=Plur	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
7	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	virus	_	NOUN	_	Number=Sing	_	_	_	_
11	or	_	CCONJ	_	_	_	_	_	_
12	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	LPS	_	NOUN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	induction	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	reveal	_	VERB	_	_	_	_	_	_
21	significant	_	ADJ	_	Degree=Pos	_	_	_	_
22	differences	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	thus	_	ADV	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	sequence	_	NOUN	_	Number=Sing	_	_	_	_
29	requirements	_	NOUN	_	Number=Plur	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	PMA	_	NOUN	_	Number=Sing	_	_	_	_
32	induction	_	NOUN	_	Number=Sing	_	_	_	_
33	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
35	from	_	ADP	_	_	_	_	_	_
36	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
37	that	_	DET	_	PronType=Rel	_	_	_	_
38	mediate	_	ADJ	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	induction	_	NOUN	_	Number=Sing	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	virus	_	NOUN	_	Number=Sing	_	_	_	_
42	or	_	CCONJ	_	_	_	_	_	_
43	LPS	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	three	_	NUM	_	NumType=Card	_	_	_	_
3	sites	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	TNF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	specifically	_	ADV	_	_	_	_	_	_
22	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	factor	_	NOUN	_	Number=Sing	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
32	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
33	extracts	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	TNF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
39	induction	_	NOUN	_	Number=Sing	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	PMA	_	PROPN	_	Number=Sing	_	_	_	_
42	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
43	not	_	PART	_	_	_	_	_	_
44	correlate	_	VERB	_	VerbForm=Inf	_	_	_	_
45	with	_	ADP	_	_	_	_	_	_
46	NF	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	kappa	_	NOUN	_	Number=Sing	_	_	_	_
49	B	_	NOUN	_	Number=Sing	_	_	_	_
50	binding	_	NOUN	_	Number=Sing	_	_	_	_
51	activities	_	NOUN	_	Number=Plur	_	_	_	_
52	displayed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
53	by	_	ADP	_	_	_	_	_	_
54	different	_	ADJ	_	Degree=Pos	_	_	_	_
55	T	_	NOUN	_	Number=Sing	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	B	_	ADJ	_	Number=Sing	_	_	_	_
58	cell	_	NOUN	_	Number=Sing	_	_	_	_
59	lines	_	NOUN	_	Number=Plur	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	kappa	_	PROPN	_	Number=Sing	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	3	_	NUM	_	NumType=Card	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	each	_	DET	_	_	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	deleted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	TNF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	alpha	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	little	_	ADJ	_	Degree=Pos	_	_	_	_
20	effect	_	NOUN	_	Number=Sing	_	_	_	_
21	on	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	's	_	PART	_	_	_	_	_	_
25	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	PMA	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	TNF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	PMA	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	like	_	ADP	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	virus	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	LPS	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	primarily	_	ADV	_	_	_	_	_	_
22	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	kappa	_	PROPN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	rather	_	ADV	_	_	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
33	through	_	ADP	_	_	_	_	_	_
34	other	_	ADJ	_	Degree=Pos	_	_	_	_
35	sequences	_	NOUN	_	Number=Plur	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	protein	_	NOUN	_	Number=Sing	_	_	_	_
38	factors	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Surprisingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	multimers	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	can	_	AUX	_	VerbForm=Fin	_	_	_	_
11	confer	_	VERB	_	VerbForm=Inf	_	_	_	_
12	PMA	_	PROPN	_	Number=Sing	_	_	_	_
13	inducibility	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	Raji	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	not	_	ADV	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	T	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	HUT78	_	NOUN	_	NumType=Card	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	line	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	functional	_	ADJ	_	Degree=Pos	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	TNF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	that	_	DET	_	_	_	_	_	_
16	promoter	_	NOUN	_	Degree=Pos	_	_	_	_
17	context	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	type	_	NOUN	_	Number=Sing	_	_	_	_
21	specificity	_	NOUN	_	Number=Sing	_	_	_	_
22	influence	_	NOUN	_	Number=Sing	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	PMA	_	PROPN	_	Number=Sing	_	_	_	_
25	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
26	function	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	kappa	_	NOUN	_	Number=Sing	_	_	_	_
32	B	_	NOUN	_	Number=Sing	_	_	_	_
33	binding	_	NOUN	_	Number=Sing	_	_	_	_
34	sites	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012906	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CTCF	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulator	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	during	_	ADP	_	_	_	_	_	_
14	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	CTCF	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	repressor	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	CTCF	_	PROPN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	characterized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	some	_	DET	_	_	_	_	_	_
8	detail	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	there	_	PRON	_	_	_	_	_	_
11	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	very	_	ADV	_	_	_	_	_	_
13	little	_	ADJ	_	Degree=Pos	_	_	_	_
14	information	_	NOUN	_	Number=Sing	_	_	_	_
15	about	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	regulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	CTCF	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	CTCF	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
8	during	_	ADP	_	_	_	_	_	_
9	induced	_	VERB	_	Degree=Pos	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
14	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	:	_	PUNCT	_	_	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	i	_	X	_	_	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	CTCF	_	PROPN	_	Number=Sing	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	down	_	ADV	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	regulated	_	VERB	_	Degree=Pos	_	_	_	_
17	during	_	ADP	_	_	_	_	_	_
18	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	most	_	ADJ	_	Degree=Sup	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	lines	_	NOUN	_	Number=Plur	_	_	_	_
24	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	;	_	PUNCT	_	_	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	ii	_	X	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	CTCF	_	PROPN	_	Number=Sing	_	_	_	_
30	down	_	ADP	_	_	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	regulation	_	NOUN	_	Number=Sing	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	retarded	_	ADJ	_	Degree=Pos	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	less	_	ADV	_	Degree=Cmp	_	_	_	_
37	pronounced	_	ADJ	_	Degree=Pos	_	_	_	_
38	than	_	ADP	_	_	_	_	_	_
39	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	c-myc	_	NOUN	_	Number=Sing	_	_	_	_
42	;	_	PUNCT	_	_	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	iii	_	X	_	_	_	_	_	_
45	)	_	PUNCT	_	_	_	_	_	_
46	CTCF	_	PROPN	_	Number=Sing	_	_	_	_
47	protein	_	NOUN	_	Number=Sing	_	_	_	_
48	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
49	differentially	_	ADV	_	_	_	_	_	_
50	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
54	profiles	_	NOUN	_	Number=Plur	_	_	_	_
55	depend	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
56	on	_	ADP	_	_	_	_	_	_
57	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
58	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
59	pathway	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	concluded	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	CTCF	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	post	_	NOUN	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
16	levels	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012912	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	C/EB	_	PROPN	_	Number=Sing	_	_	_	_
2	Pbeta	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	GATA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	synergistically	_	ADV	_	_	_	_	_	_
8	regulate	_	VERB	_	Degree=Pos	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	eosinophil	_	NOUN	_	Number=Sing	_	_	_	_
13	granule	_	NOUN	_	Number=Sing	_	_	_	_
14	major	_	ADJ	_	Degree=Pos	_	_	_	_
15	basic	_	ADJ	_	Degree=Pos	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	:	_	PUNCT	_	_	_	_	_	_
19	implication	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	C	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	EBPbeta	_	PROPN	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	eosinophil	_	ADJ	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Eosinophil	_	PROPN	_	Number=Sing	_	_	_	_
2	granule	_	NOUN	_	Number=Sing	_	_	_	_
3	major	_	ADJ	_	Degree=Pos	_	_	_	_
4	basic	_	ADJ	_	Degree=Pos	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	MBP	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	exclusively	_	ADV	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	basophils	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
3	previous	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	major	_	ADJ	_	Degree=Pos	_	_	_	_
10	positive	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	role	_	NOUN	_	Number=Sing	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	GATA	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	negative	_	ADJ	_	Degree=Pos	_	_	_	_
20	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	GATA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	MBP	_	NOUN	_	Number=Sing	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	MBP	_	NOUN	_	Number=Sing	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	C/EBP	_	PROPN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	CCAAT	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	VERB	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	consensus	_	NOUN	_	Number=Sing	_	_	_	_
20	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	6	_	NUM	_	NumType=Card	_	_	_	_
23	bp	_	NOUN	_	Number=Sing	_	_	_	_
24	upstream	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	functional	_	ADJ	_	Degree=Pos	_	_	_	_
28	GATA	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	MBP	_	NOUN	_	Number=Sing	_	_	_	_
35	gene	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	line	_	NOUN	_	Number=Sing	_	_	_	_
5	HT93A	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	capable	_	ADJ	_	Degree=Pos	_	_	_	_
10	of	_	SCONJ	_	_	_	_	_	_
11	differentiating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	towards	_	ADP	_	_	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	eosinophil	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
18	lineages	_	NOUN	_	Number=Plur	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	response	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	retinoic	_	PROPN	_	Degree=Pos	_	_	_	_
23	acid	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	RA	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	C/EBPalpha	_	PROPN	_	Number=Sing	_	_	_	_
29	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	significantly	_	ADV	_	_	_	_	_	_
33	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	eosinophilic	_	ADJ	_	Degree=Pos	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	neutrophilic	_	ADJ	_	Degree=Pos	_	_	_	_
38	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	whereas	_	SCONJ	_	_	_	_	_	_
41	C	_	PROPN	_	Number=Sing	_	_	_	_
42	/	_	PUNCT	_	_	_	_	_	_
43	EBPbeta	_	PROPN	_	Number=Sing	_	_	_	_
44	expression	_	NOUN	_	Number=Sing	_	_	_	_
45	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
46	markedly	_	ADV	_	_	_	_	_	_
47	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EMSAs	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	recombinant	_	NOUN	_	Degree=Pos	_	_	_	_
11	C/EBPbeta	_	PROPN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	could	_	AUX	_	VerbForm=Fin	_	_	_	_
14	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	potential	_	ADJ	_	Degree=Pos	_	_	_	_
18	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	site	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	bp	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	90	_	NUM	_	NumType=Card	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	-	_	SYM	_	_	_	_	_	_
28	82	_	NUM	_	NumType=Card	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	MBP	_	NOUN	_	Number=Sing	_	_	_	_
33	promoter	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	both	_	CCONJ	_	_	_	_	_	_
8	C/EBPbeta	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	GATA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	can	_	AUX	_	VerbForm=Fin	_	_	_	_
14	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
15	simultaneously	_	ADV	_	_	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	GATA	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	binding	_	VERB	_	Number=Sing	_	_	_	_
24	sites	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	MBP	_	NOUN	_	Number=Sing	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	functionality	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	GATA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	sites	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
17	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	whether	_	SCONJ	_	_	_	_	_	_
19	C/EBPbeta	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	GATA	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	can	_	AUX	_	VerbForm=Fin	_	_	_	_
25	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	MBP	_	NOUN	_	Number=Sing	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	C/EBPbeta	_	PROPN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	GATA	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	negative	_	ADJ	_	Degree=Pos	_	_	_	_
37	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
38	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
39	line	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	C/EBPbeta	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	GATA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	vectors	_	NOUN	_	Number=Plur	_	_	_	_
10	produced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	5	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	fold	_	NOUN	_	Number=Sing	_	_	_	_
15	increase	_	NOUN	_	Number=Sing	_	_	_	_
16	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	C/EBPbeta	_	PROPN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	GATA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	expression	_	NOUN	_	Number=Sing	_	_	_	_
27	vectors	_	NOUN	_	Number=Plur	_	_	_	_
28	individually	_	ADV	_	_	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	GST	_	PROPN	_	Number=Sing	_	_	_	_
5	pull	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	down	_	ADP	_	Number=Sing	_	_	_	_
8	experiments	_	NOUN	_	Number=Plur	_	_	_	_
9	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	physical	_	ADJ	_	Degree=Pos	_	_	_	_
12	interaction	_	NOUN	_	Number=Sing	_	_	_	_
13	between	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	GATA	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	C/EBPbeta	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	FOG	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	riend	_	NOUN	_	Number=Sing	_	_	_	_
6	ATA	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	GATA	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	acts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	cofactor	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	GATA	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	binding	_	VERB	_	Number=Sing	_	_	_	_
24	proteins	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
28	activity	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	GATA	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	SYM	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	for	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	MBP	_	NOUN	_	Number=Sing	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	dose	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
42	manner	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
6	evidence	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	GATA	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	C/EBPbeta	_	PROPN	_	Number=Sing	_	_	_	_
14	synergistically	_	ADV	_	_	_	_	_	_
15	transactivate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	promoter	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	eosinophil	_	ADJ	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	granule	_	NOUN	_	Number=Sing	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	that	_	SCONJ	_	_	_	_	_	_
28	FOG	_	NOUN	_	Number=Sing	_	_	_	_
29	may	_	AUX	_	VerbForm=Fin	_	_	_	_
30	act	_	VERB	_	VerbForm=Inf	_	_	_	_
31	as	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	negative	_	ADJ	_	Degree=Pos	_	_	_	_
34	cofactor	_	NOUN	_	Number=Sing	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	eosinophil	_	ADJ	_	Number=Sing	_	_	_	_
38	lineage	_	NOUN	_	Number=Sing	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	unlike	_	ADP	_	_	_	_	_	_
41	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
42	positively	_	ADV	_	_	_	_	_	_
43	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
44	function	_	NOUN	_	Number=Sing	_	_	_	_
45	for	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	megakaryocyte	_	NOUN	_	Number=Sing	_	_	_	_
50	lineages	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012918	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	INTJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_

1	Nef	_	ADV	_	Number=Sing	_	_	_	_
2	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	depending	_	VERB	_	VerbForm=Ger	_	_	_	_
11	on	_	ADP	_	_	_	_	_	_
12	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
13	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
14	localization	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Nef	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	primate	_	ADJ	_	Degree=Pos	_	_	_	_
4	lentiviruses	_	NOUN	_	Number=Plur	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	viremia	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	progression	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	monkeys	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Negative	_	ADJ	_	Degree=Pos	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	positive	_	ADJ	_	Degree=Pos	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	no	_	DET	_	_	_	_	_	_
7	effects	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	Nef	_	PROPN	_	Number=Sing	_	_	_	_
10	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
13	reported	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	viral	_	ADJ	_	Degree=Pos	_	_	_	_
16	replication	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	reconcile	_	VERB	_	VerbForm=Inf	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	observations	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
10	CD8	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	Nef	_	NOUN	_	Number=Sing	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	opposite	_	ADJ	_	Degree=Pos	_	_	_	_
3	phenotypes	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Int	_	_	_	_
8	depended	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
12	localization	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	Nef	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
5	or	_	CCONJ	_	_	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	surface	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	chimera	_	NOUN	_	Number=Sing	_	_	_	_
13	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	early	_	ADJ	_	Degree=Pos	_	_	_	_
17	signaling	_	VERB	_	Number=Sing	_	_	_	_
18	events	_	NOUN	_	Number=Plur	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	antigen	_	NOUN	_	Number=Sing	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	died	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	only	_	ADV	_	_	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	mutated	_	VERB	_	Degree=Pos	_	_	_	_
13	nef	_	ADJ	_	Degree=Pos	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	truncated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
17	Nefs	_	PROPN	_	Number=Sing	_	_	_	_
18	survived	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	rendered	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	Nef	_	PROPN	_	Number=Sing	_	_	_	_
23	nonfunctional	_	ADJ	_	Degree=Pos	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	mutations	_	NOUN	_	Number=Plur	_	_	_	_
3	paralleled	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	other	_	ADJ	_	Degree=Pos	_	_	_	_
7	viral	_	ADJ	_	Degree=Pos	_	_	_	_
8	strains	_	NOUN	_	Number=Plur	_	_	_	_
9	passaged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	vitro	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Not	_	ADV	_	_	_	_	_	_
2	only	_	ADV	_	_	_	_	_	_
3	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	positional	_	ADJ	_	Degree=Pos	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	Nef	_	PROPN	_	Number=Sing	_	_	_	_
9	reconcile	_	VERB	_	Number=Sing	_	_	_	_
10	diverse	_	ADJ	_	Degree=Pos	_	_	_	_
11	phenotypes	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	Nef	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	N	_	ADJ	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	terminal	_	NOUN	_	Number=Sing	_	_	_	_
23	myristylation	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
27	also	_	ADV	_	_	_	_	_	_
28	explain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	effects	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	Nef	_	PROPN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	HIV	_	NOUN	_	Number=Sing	_	_	_	_
34	infection	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	progression	_	NOUN	_	Number=Sing	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	AIDS	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012929	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
10	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	kappa	_	VERB	_	Number=Sing	_	_	_	_
13	B	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	MAD	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	Mycobacterium	_	PROPN	_	Number=Sing	_	_	_	_
24	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	during	_	ADP	_	_	_	_	_	_
27	human	_	ADJ	_	Degree=Pos	_	_	_	_
28	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Blood	_	NOUN	_	Number=Sing	_	_	_	_
2	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	patients	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	active	_	ADJ	_	Degree=Pos	_	_	_	_
7	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
8	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	vivo	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	as	_	SCONJ	_	_	_	_	_	_
14	evidenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	increase	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	release	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
24	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	such	_	ADJ	_	Degree=Pos	_	_	_	_
27	as	_	ADP	_	_	_	_	_	_
28	TNF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	spontaneous	_	ADJ	_	Degree=Pos	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2R	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	patients	_	NOUN	_	Number=Plur	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	augmented	_	VERB	_	Degree=Pos	_	_	_	_
9	susceptibility	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	productive	_	ADJ	_	Degree=Pos	_	_	_	_
13	infection	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	vitro	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Mycobacterium	_	PROPN	_	Number=Sing	_	_	_	_
2	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
5	components	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	strong	_	ADJ	_	Degree=Pos	_	_	_	_
8	signals	_	NOUN	_	Number=Plur	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	production	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	basis	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	during	_	ADP	_	_	_	_	_	_
13	active	_	ADJ	_	Degree=Pos	_	_	_	_
14	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	M.	_	PROPN	_	Number=Sing	_	_	_	_
18	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
5	degradation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	kappa	_	VERB	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	alpha	_	PROPN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	major	_	ADJ	_	Degree=Pos	_	_	_	_
15	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
16	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	freshly	_	ADV	_	_	_	_	_	_
31	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	from	_	ADP	_	_	_	_	_	_
36	patients	_	NOUN	_	Number=Sing	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	tuberculosis	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	kappa	_	VERB	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	levels	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	from	_	ADP	_	_	_	_	_	_
15	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
16	subjects	_	NOUN	_	Number=Plur	_	_	_	_
17	or	_	CCONJ	_	_	_	_	_	_
18	from	_	ADP	_	_	_	_	_	_
19	patients	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	nontuberculous	_	ADJ	_	Degree=Pos	_	_	_	_
22	pulmonary	_	ADJ	_	Degree=Pos	_	_	_	_
23	conditions	_	NOUN	_	Number=Plur	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	intact	_	VERB	_	Degree=Pos	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
5	mobility	_	NOUN	_	Number=Sing	_	_	_	_
6	shift	_	NOUN	_	Number=Sing	_	_	_	_
7	assay	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	PROPN	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	tuberculous	_	ADJ	_	Degree=Pos	_	_	_	_
19	patients	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
5	kappa	_	VERB	_	Number=Sing	_	_	_	_
6	B	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha	_	PROPN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	up	_	ADV	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	patients	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	but	_	CCONJ	_	_	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	mononuclear	_	ADJ	_	Degree=Pos	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	from	_	ADP	_	_	_	_	_	_
39	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
40	subjects	_	NOUN	_	Number=Plur	_	_	_	_
41	or	_	CCONJ	_	_	_	_	_	_
42	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
43	with	_	ADP	_	_	_	_	_	_
44	nontuberculous	_	ADJ	_	Degree=Pos	_	_	_	_
45	lung	_	NOUN	_	Number=Sing	_	_	_	_
46	diseases	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	other	_	ADJ	_	Degree=Pos	_	_	_	_
8	adherence	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	early	_	ADJ	_	Degree=Pos	_	_	_	_
12	genes	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	such	_	ADJ	_	Degree=Pos	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	8	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	beta	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	up	_	ADP	_	_	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	PBMC	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	tuberculous	_	ADJ	_	Degree=Pos	_	_	_	_
34	patients	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Further	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	M.	_	PROPN	_	Number=Sing	_	_	_	_
4	tuberculosis	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
7	tuberculin	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	derivative	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	degradation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
27	kappa	_	VERB	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	derivative	_	NOUN	_	Number=Sing	_	_	_	_
37	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	NF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	kappa	_	NOUN	_	Number=Sing	_	_	_	_
44	B	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012933	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Mapping	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	interaction	_	NOUN	_	Number=Sing	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	defective	_	ADJ	_	Degree=Pos	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factor	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	class	_	NOUN	_	Number=Sing	_	_	_	_
14	II	_	NUM	_	NumType=Card	_	_	_	_
15	major	_	ADJ	_	Degree=Pos	_	_	_	_
16	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
17	complex	_	NOUN	_	Number=Sing	_	_	_	_
18	mutant	_	NOUN	_	Degree=Pos	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	line	_	NOUN	_	Number=Sing	_	_	_	_
21	clone	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	13	_	NUM	_	NumType=Card	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	divergent	_	ADJ	_	Number=Sing	_	_	_	_
27	X2	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	box	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	previously	_	ADV	_	_	_	_	_	_
4	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	mutant	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	PROPN	_	Number=Sing	_	_	_	_
8	lymphoblastoid	_	NOUN	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	Clone	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	13	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	expresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	HLA	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	DQ	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	absence	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	HLA	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	DR	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	DP	_	PROPN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	criteria	_	NOUN	_	Number=Plur	_	_	_	_
3	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	defect	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	line	_	NOUN	_	Number=Sing	_	_	_	_
11	influences	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	isotype	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Indeed	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	transient	_	ADJ	_	Degree=Pos	_	_	_	_
4	transfection	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	HLA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	DRA	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	DQB	_	NOUN	_	Number=Sing	_	_	_	_
11	reporter	_	NOUN	_	Number=Sing	_	_	_	_
12	constructs	_	NOUN	_	Number=Plur	_	_	_	_
13	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	operates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	via	_	ADP	_	_	_	_	_	_
20	cis	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	elements	_	NOUN	_	Number=Plur	_	_	_	_
23	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	between	_	ADP	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	141	_	NUM	_	NumType=Card	_	_	_	_
27	base	_	NOUN	_	Number=Sing	_	_	_	_
28	pairs	_	NOUN	_	Number=Plur	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	initiation	_	NOUN	_	Number=Sing	_	_	_	_
33	site	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	series	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
5	DRA	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	DQB	_	NOUN	_	Number=Sing	_	_	_	_
8	reporter	_	NOUN	_	Number=Sing	_	_	_	_
9	constructs	_	NOUN	_	Number=Plur	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	generated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	further	_	ADJ	_	Degree=Pos	_	_	_	_
14	map	_	NOUN	_	VerbForm=Inf	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
17	cis	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	elements	_	NOUN	_	Number=Plur	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
22	system	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Insertion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
4	spanning	_	VERB	_	VerbForm=Ger	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	DQB	_	PROPN	_	Number=Sing	_	_	_	_
7	X-box	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	but	_	CCONJ	_	_	_	_	_	_
10	not	_	ADV	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	DQB	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	W	_	ADJ	_	Number=Sing	_	_	_	_
15	region	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	DQB	_	PROPN	_	Number=Sing	_	_	_	_
19	Y	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	box	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	upstream	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	141	_	NUM	_	NumType=Card	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	DRA	_	PROPN	_	Number=Sing	_	_	_	_
30	reporter	_	NOUN	_	Number=Sing	_	_	_	_
31	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
32	rescued	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	expression	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	nearly	_	ADV	_	_	_	_	_	_
36	wild	_	ADJ	_	Degree=Pos	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	type	_	NOUN	_	Number=Sing	_	_	_	_
39	levels	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Substitution	_	NOUN	_	Number=Sing	_	_	_	_
2	promoters	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	then	_	ADV	_	PronType=Dem	_	_	_	_
5	generated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	where	_	ADV	_	PronType=Int	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	entire	_	ADJ	_	Degree=Pos	_	_	_	_
9	X	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	box	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	only	_	ADV	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	X1	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	X2	_	NUM	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	boxes	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	HLA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	DRA	_	PROPN	_	Number=Sing	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	replaced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	analogous	_	ADJ	_	Degree=Pos	_	_	_	_
31	regions	_	NOUN	_	Number=Plur	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	HLA	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	DQB	_	PROPN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	DQB	_	PROPN	_	Number=Sing	_	_	_	_
3	X2	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	box	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	able	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	restore	_	VERB	_	VerbForm=Inf	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	silent	_	ADJ	_	Degree=Pos	_	_	_	_
14	DRA	_	PROPN	_	Number=Sing	_	_	_	_
15	reporter	_	NOUN	_	Number=Sing	_	_	_	_
16	construct	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	replacement	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	DQB	_	PROPN	_	Number=Sing	_	_	_	_
7	X2	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	box	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	DRA	_	PROPN	_	Number=Sing	_	_	_	_
13	X2	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	box	_	NOUN	_	Number=Sing	_	_	_	_
16	markedly	_	ADV	_	_	_	_	_	_
17	diminished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	DQB	_	NOUN	_	Number=Sing	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	mutant	_	NOUN	_	Degree=Pos	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	None	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	hybrid	_	NOUN	_	Number=Sing	_	_	_	_
5	reporter	_	NOUN	_	Number=Sing	_	_	_	_
6	constructs	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	defective	_	ADJ	_	Degree=Pos	_	_	_	_
9	when	_	ADV	_	PronType=Int	_	_	_	_
10	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	into	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	wild	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	type	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	HLA	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	DR	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	DQ	_	NOUN	_	Number=Sing	_	_	_	_
23	positive	_	ADJ	_	Degree=Pos	_	_	_	_
24	parental	_	NOUN	_	Degree=Pos	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	line	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	Jijoye	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	divergent	_	ADJ	_	Degree=Pos	_	_	_	_
7	X2	_	NUM	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	box	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	class	_	NOUN	_	Number=Sing	_	_	_	_
13	II	_	NUM	_	NumType=Card	_	_	_	_
14	major	_	ADJ	_	Degree=Pos	_	_	_	_
15	histocompatibility	_	NOUN	_	Number=Sing	_	_	_	_
16	complex	_	NOUN	_	Number=Sing	_	_	_	_
17	promoters	_	NOUN	_	Number=Plur	_	_	_	_
18	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	important	_	ADJ	_	Degree=Pos	_	_	_	_
21	role	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	SCONJ	_	_	_	_	_	_
23	influencing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	differential	_	ADJ	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	class	_	NOUN	_	Number=Sing	_	_	_	_
30	II	_	NUM	_	NumType=Card	_	_	_	_
31	isotypes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012934	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Multiple	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	9	_	NUM	_	NumType=Card	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	T	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
3	elements	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
6	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
7	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	9	_	NUM	_	NumType=Card	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	9	_	NUM	_	NumType=Card	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
25	virus	_	NOUN	_	Number=Sing	_	_	_	_
26	type	_	NOUN	_	Number=Sing	_	_	_	_
27	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	cell	_	NOUN	_	Number=Sing	_	_	_	_
33	line	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	C5MJ2	_	NOUN	_	Number=Sing	_	_	_	_
36	,	_	PUNCT	_	_	_	_	_	_
37	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
38	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	9	_	NUM	_	NumType=Card	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	at	_	ADV	_	_	_	_	_	_
13	least	_	ADV	_	Degree=Sup	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	part	_	ADJ	_	Degree=Pos	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Transient	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
6	reporter	_	NOUN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	serially	_	ADV	_	_	_	_	_	_
11	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	sequences	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	5'-	_	NOUN	_	_	_	_	_	_
16	flanking	_	VERB	_	Number=Sing	_	_	_	_
17	region	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	9	_	NUM	_	NumType=Card	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	several	_	ADJ	_	Degree=Pos	_	_	_	_
27	positive	_	ADJ	_	Degree=Pos	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	negative	_	ADJ	_	Degree=Pos	_	_	_	_
30	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	elements	_	NOUN	_	Number=Plur	_	_	_	_
32	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	basal	_	ADJ	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
38	expression	_	NOUN	_	Number=Sing	_	_	_	_
39	of	_	ADP	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	9	_	NUM	_	NumType=Card	_	_	_	_
44	gene	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	C5MJ2	_	PROPN	_	Number=Sing	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	An	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	AP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	at	_	ADP	_	_	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	146	_	NUM	_	NumType=Card	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	-	_	SYM	_	_	_	_	_	_
11	140	_	NUM	_	NumType=Card	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	involved	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	9	_	NUM	_	NumType=Card	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	between	_	ADP	_	_	_	_	_	_
5	-	_	SYM	_	_	_	_	_	_
6	46	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	-	_	SYM	_	_	_	_	_	_
9	80	_	NUM	_	NumType=Card	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	as	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	minimum	_	ADJ	_	Degree=Pos	_	_	_	_
15	sequence	_	NOUN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	basal	_	ADJ	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	9	_	NUM	_	NumType=Card	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	C5MJ2	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Within	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	region	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	at	_	ADP	_	_	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	59	_	NUM	_	NumType=Card	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	50	_	NUM	_	NumType=Card	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
19	20	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	base	_	NOUN	_	Number=Sing	_	_	_	_
22	pair	_	NOUN	_	Number=Sing	_	_	_	_
23	upstream	_	NOUN	_	Degree=Pos	_	_	_	_
24	sequence	_	NOUN	_	Number=Sing	_	_	_	_
25	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
26	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	play	_	VERB	_	VerbForm=Inf	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	critical	_	ADJ	_	Degree=Pos	_	_	_	_
31	role	_	NOUN	_	Number=Sing	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	9	_	NUM	_	NumType=Card	_	_	_	_
37	promoter	_	NOUN	_	Number=Sing	_	_	_	_
38	activity	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	binding	_	NOUN	_	Number=Sing	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	c	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	Jun	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	potentially	_	ADV	_	_	_	_	_	_
18	novel	_	NOUN	_	Number=Sing	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	around	_	ADV	_	_	_	_	_	_
22	35	_	NUM	_	NumType=Card	_	_	_	_
23	kDa	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	can	_	AUX	_	VerbForm=Fin	_	_	_	_
26	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
29	important	_	ADJ	_	Degree=Pos	_	_	_	_
30	sequence	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Mutations	_	NOUN	_	Number=Plur	_	_	_	_
2	at	_	ADP	_	_	_	_	_	_
3	different	_	ADJ	_	Degree=Pos	_	_	_	_
4	sites	_	NOUN	_	Number=Plur	_	_	_	_
5	within	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	abolished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	as	_	ADV	_	_	_	_	_	_
15	well	_	ADV	_	Degree=Pos	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	DNA	_	PROPN	_	Number=Sing	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	different	_	ADJ	_	Degree=Pos	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	essential	_	ADJ	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	9	_	NUM	_	NumType=Card	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	T	_	PROPN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012935	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	AML1	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	CBFalpha2	_	X	_	Number=Sing	_	_	_	_
4	)	_	PUNCT	_	_	_	_	_	_
5	cooperates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	B	_	NOUN	_	Degree=Pos	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	activating	_	NOUN	_	Number=Sing	_	_	_	_
12	protein	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	BSAP	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	PAX5	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	activation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	BLK	_	PROPN	_	Number=Sing	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	promoter	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	AML1	_	PROPN	_	Number=Sing	_	_	_	_
2	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	critical	_	ADJ	_	Degree=Pos	_	_	_	_
5	role	_	NOUN	_	Number=Sing	_	_	_	_
6	during	_	ADP	_	_	_	_	_	_
7	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	chromosomal	_	ADJ	_	Degree=Pos	_	_	_	_
10	translocations	_	NOUN	_	Number=Plur	_	_	_	_
11	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
12	AML1	_	PROPN	_	Number=Plur	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	commonly	_	ADV	_	_	_	_	_	_
15	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	different	_	ADJ	_	Degree=Pos	_	_	_	_
18	forms	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	including	_	VERB	_	VerbForm=Ger	_	_	_	_
23	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
24	acute	_	ADJ	_	Degree=Pos	_	_	_	_
25	lymphoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
26	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	function	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	AML1	_	NOUN	_	Number=Sing	_	_	_	_
7	during	_	ADP	_	_	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
13	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
15	regions	_	NOUN	_	Number=Plur	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	B	_	ADJ	_	Degree=Pos	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	for	_	ADP	_	_	_	_	_	_
23	potential	_	ADJ	_	Degree=Pos	_	_	_	_
24	AML1	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	binding	_	VERB	_	Number=Sing	_	_	_	_
27	sites	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
30	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	putative	_	ADJ	_	Degree=Pos	_	_	_	_
33	AML1	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	binding	_	NOUN	_	Number=Sing	_	_	_	_
36	site	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	promoter	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	B	_	PROPN	_	Number=Sing	_	_	_	_
43	cell	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	specific	_	ADJ	_	Degree=Pos	_	_	_	_
46	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
47	kinase	_	NOUN	_	Number=Sing	_	_	_	_
48	gene	_	NOUN	_	Number=Sing	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	blk	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Gel	_	NOUN	_	Number=Sing	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assays	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	transient	_	ADJ	_	Degree=Pos	_	_	_	_
7	transfection	_	NOUN	_	Number=Sing	_	_	_	_
8	assays	_	NOUN	_	Number=Plur	_	_	_	_
9	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	AML1	_	PROPN	_	Number=Sing	_	_	_	_
12	binds	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	specifically	_	ADV	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
16	site	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	blk	_	NOUN	_	Number=Sing	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
23	binding	_	NOUN	_	Number=Sing	_	_	_	_
24	site	_	NOUN	_	Number=Sing	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	important	_	ADJ	_	Degree=Pos	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	blk	_	NOUN	_	Number=Sing	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vitro	_	ADJ	_	Number=Sing	_	_	_	_
5	binding	_	VERB	_	Number=Sing	_	_	_	_
6	analysis	_	NOUN	_	Number=Sing	_	_	_	_
7	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	AML1	_	PROPN	_	Number=Sing	_	_	_	_
11	runt	_	NOUN	_	Number=Sing	_	_	_	_
12	DNA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	binding	_	VERB	_	Number=Sing	_	_	_	_
15	domain	_	NOUN	_	Number=Sing	_	_	_	_
16	physically	_	ADV	_	_	_	_	_	_
17	interacts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	paired	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	binding	_	VERB	_	Number=Sing	_	_	_	_
24	domain	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	BSAP	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	B	_	NOUN	_	Degree=Pos	_	_	_	_
30	cell	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	specific	_	ADJ	_	Degree=Pos	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	factor	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	BSAP	_	PROPN	_	Number=Sing	_	_	_	_
2	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	previously	_	ADV	_	_	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	important	_	ADJ	_	Degree=Pos	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	B	_	ADJ	_	Degree=Pos	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	regulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	blk	_	NOUN	_	Degree=Pos	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Physical	_	ADJ	_	Degree=Pos	_	_	_	_
2	interaction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	AML1	_	NOUN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	BSAP	_	NOUN	_	Number=Sing	_	_	_	_
7	correlates	_	VERB	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	functional	_	ADJ	_	Degree=Pos	_	_	_	_
10	cooperativity	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	transfection	_	NOUN	_	Number=Sing	_	_	_	_
13	studies	_	NOUN	_	Number=Plur	_	_	_	_
14	where	_	ADV	_	PronType=Rel	_	_	_	_
15	AML1	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	BSAP	_	PROPN	_	Number=Sing	_	_	_	_
18	synergistically	_	ADV	_	_	_	_	_	_
19	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	blk	_	NOUN	_	Number=Sing	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	more	_	ADJ	_	Degree=Cmp	_	_	_	_
25	than	_	ADP	_	_	_	_	_	_
26	50	_	NUM	_	NumType=Card	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	fold	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	physical	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	functional	_	ADJ	_	Degree=Pos	_	_	_	_
7	interactions	_	NOUN	_	Number=Plur	_	_	_	_
8	between	_	ADP	_	_	_	_	_	_
9	AML1	_	PROPN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	BSAP	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	AML1	_	PROPN	_	Number=Sing	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	important	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	SCONJ	_	_	_	_	_	_
21	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	critical	_	ADJ	_	Degree=Pos	_	_	_	_
24	B	_	NOUN	_	Degree=Pos	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	blk	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012937	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	shortened	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	life	_	NOUN	_	Number=Sing	_	_	_	_
4	span	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
7	-/-	_	PUNCT	_	_	_	_	_	_
8	adult	_	NOUN	_	Number=Sing	_	_	_	_
9	erythrocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	due	_	ADP	_	_	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	deficiency	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	beta	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	globin	_	ADJ	_	Degree=Pos	_	_	_	_
19	chains	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	ameliorated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	gamma	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	globin	_	NOUN	_	Degree=Pos	_	_	_	_
28	chains	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	homologous	_	ADJ	_	Degree=Pos	_	_	_	_
3	recombination	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	both	_	CCONJ	_	_	_	_	_	_
6	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
7	alleles	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	murine	_	NOUN	_	Number=Sing	_	_	_	_
10	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
11	stem	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	ES	_	X	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	inactivated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
3	-/-	_	PUNCT	_	_	_	_	_	_
4	ES	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	capable	_	ADJ	_	Degree=Pos	_	_	_	_
8	of	_	SCONJ	_	_	_	_	_	_
9	undergoing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	vitro	_	ADJ	_	Number=Sing	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	form	_	VERB	_	VerbForm=Inf	_	_	_	_
15	definitive	_	ADJ	_	Degree=Pos	_	_	_	_
16	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
17	colonies	_	NOUN	_	Number=Plur	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	similar	_	ADJ	_	Degree=Pos	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	size	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	number	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
27	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	wild	_	ADJ	_	Degree=Pos	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	type	_	NOUN	_	Number=Sing	_	_	_	_
32	ES	_	PROPN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
5	-/-	_	PUNCT	_	_	_	_	_	_
6	colonies	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	poorly	_	ADV	_	_	_	_	_	_
9	hemoglobinized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	enucleated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	erythrocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	colonies	_	NOUN	_	Number=Plur	_	_	_	_
16	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	numerous	_	ADJ	_	Degree=Pos	_	_	_	_
18	Heinz	_	NOUN	_	Number=Sing	_	_	_	_
19	bodies	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Reverse	_	ADJ	_	_	_	_	_	_
2	transcriptase	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
5	chain	_	NOUN	_	Number=Sing	_	_	_	_
6	reaction	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	RT	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	PCR	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	analyses	_	NOUN	_	Number=Plur	_	_	_	_
13	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	adult	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
18	globin	_	NOUN	_	Degree=Pos	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	appropriately	_	ADV	_	_	_	_	_	_
22	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	exception	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	beta	_	NOUN	_	Number=Sing	_	_	_	_
29	h1	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	globin	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	which	_	PRON	_	PronType=Rel	_	_	_	_
34	continued	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	be	_	AUX	_	VerbForm=Inf	_	_	_	_
37	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	at	_	ADP	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	very	_	ADV	_	_	_	_	_	_
41	low	_	ADJ	_	Degree=Pos	_	_	_	_
42	level	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	ratio	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	adult	_	NOUN	_	Number=Sing	_	_	_	_
5	beta-globin	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	globin	_	VERB	_	Degree=Pos	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	mutant	_	ADJ	_	Number=Sing	_	_	_	_
14	ES	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	1/15	_	NUM	_	NumType=Card	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	wild	_	ADJ	_	Degree=Pos	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	type	_	NOUN	_	Number=Sing	_	_	_	_
24	ES	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
4	-/-	_	PUNCT	_	_	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	injected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	into	_	ADP	_	_	_	_	_	_
9	blastocysts	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
12	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	not	_	PART	_	_	_	_	_	_
14	contribute	_	VERB	_	VerbForm=Inf	_	_	_	_
15	at	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
18	level	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	mature	_	ADJ	_	Degree=Pos	_	_	_	_
22	erythrocyte	_	NOUN	_	Number=Sing	_	_	_	_
23	compartment	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	chimeric	_	ADJ	_	Degree=Pos	_	_	_	_
27	animals	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	on	_	ADP	_	_	_	_	_	_
31	analysis	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	glucose	_	ADJ	_	Number=Sing	_	_	_	_
34	phosphate	_	NOUN	_	Number=Sing	_	_	_	_
35	isomerase	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	GPI	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	1	_	NUM	_	NumType=Card	_	_	_	_
42	)	_	PUNCT	_	_	_	_	_	_
43	isozymes	_	NOUN	_	Number=Plur	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	hemoglobins	_	NOUN	_	Number=Plur	_	_	_	_
46	that	_	PRON	_	PronType=Rel	_	_	_	_
47	distinguish	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
48	ES	_	PROPN	_	Number=Sing	_	_	_	_
49	cell	_	NOUN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
52	erythrocytes	_	NOUN	_	Number=Plur	_	_	_	_
53	from	_	ADP	_	_	_	_	_	_
54	host	_	ADJ	_	Number=Sing	_	_	_	_
55	blastocyst	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
58	erythrocytes	_	NOUN	_	Number=Plur	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	semiquantitative	_	ADJ	_	Degree=Pos	_	_	_	_
5	RT	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	PCR	_	NOUN	_	Number=Sing	_	_	_	_
8	analysis	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	RNA	_	PROPN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	reticulocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	same	_	ADJ	_	Degree=Pos	_	_	_	_
16	chimeric	_	ADJ	_	Degree=Pos	_	_	_	_
17	animals	_	NOUN	_	Number=Plur	_	_	_	_
18	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	ES	_	PROPN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	reticulocytes	_	NOUN	_	Number=Plur	_	_	_	_
26	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	present	_	ADJ	_	Degree=Pos	_	_	_	_
28	at	_	ADP	_	_	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	level	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	6	_	NUM	_	NumType=Card	_	_	_	_
33	%	_	SYM	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	8	_	NUM	_	NumType=Card	_	_	_	_
36	%	_	SYM	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
6	-/-	_	PUNCT	_	_	_	_	_	_
7	erythrocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	adult	_	ADJ	_	Degree=Pos	_	_	_	_
10	animals	_	NOUN	_	Number=Plur	_	_	_	_
11	must	_	AUX	_	VerbForm=Fin	_	_	_	_
12	be	_	AUX	_	VerbForm=Inf	_	_	_	_
13	short	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	lived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	apparently	_	ADV	_	_	_	_	_	_
18	due	_	ADP	_	_	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	imbalance	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	beta	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	versus	_	ADP	_	_	_	_	_	_
26	alpha	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	globin	_	ADJ	_	Degree=Pos	_	_	_	_
29	chains	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	precipitation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	excess	_	ADJ	_	VerbForm=Ger	_	_	_	_
37	alpha	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	globin	_	ADJ	_	Degree=Pos	_	_	_	_
40	chains	_	NOUN	_	Number=Plur	_	_	_	_
41	to	_	PART	_	_	_	_	_	_
42	form	_	VERB	_	VerbForm=Inf	_	_	_	_
43	Heinz	_	PROPN	_	Number=Sing	_	_	_	_
44	bodies	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	short	_	ADJ	_	Degree=Pos	_	_	_	_
8	life	_	NOUN	_	Number=Sing	_	_	_	_
9	span	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	ameliorated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	introduction	_	NOUN	_	Number=Sing	_	_	_	_
14	into	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	EKLF	_	PROPN	_	Number=Sing	_	_	_	_
17	-/-	_	PUNCT	_	_	_	_	_	_
18	ES	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	LCR	_	NOUN	_	Number=Sing	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	gamma	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	globin	_	NOUN	_	Degree=Pos	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	as	_	SCONJ	_	_	_	_	_	_
31	evidenced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	presence	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	ES	_	PROPN	_	Number=Sing	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	reticulocytes	_	NOUN	_	Number=Plur	_	_	_	_
41	as	_	ADV	_	_	_	_	_	_
42	well	_	ADV	_	Degree=Pos	_	_	_	_
43	as	_	ADP	_	_	_	_	_	_
44	mature	_	ADJ	_	Degree=Pos	_	_	_	_
45	erythrocytes	_	NOUN	_	Number=Plur	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
48	blood	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	chimeric	_	ADJ	_	Degree=Pos	_	_	_	_
52	animals	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012942	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	vivo	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
13	phosphorylations	_	NOUN	_	Number=Plur	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	intact	_	NOUN	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	mechanistically	_	ADV	_	_	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	well	_	ADV	_	Degree=Pos	_	_	_	_
21	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	modifications	_	NOUN	_	Number=Plur	_	_	_	_
6	imposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	/	_	PUNCT	_	_	_	_	_	_
13	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
14	kappa	_	VERB	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	components	_	NOUN	_	Number=Plur	_	_	_	_
17	following	_	VERB	_	VerbForm=Ger	_	_	_	_
18	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	final	_	ADJ	_	Degree=Pos	_	_	_	_
24	step	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	induction	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	vivo	_	NOUN	_	Number=Sing	_	_	_	_
33	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	several	_	ADJ	_	Degree=Pos	_	_	_	_
37	members	_	NOUN	_	Number=Plur	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	NF	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	kappa	_	NOUN	_	Number=Sing	_	_	_	_
43	B	_	NOUN	_	Number=Sing	_	_	_	_
44	/	_	PUNCT	_	_	_	_	_	_
45	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
46	kappa	_	VERB	_	Number=Sing	_	_	_	_
47	B	_	NOUN	_	Number=Sing	_	_	_	_
48	protein	_	NOUN	_	Number=Sing	_	_	_	_
49	families	_	NOUN	_	Number=Plur	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	as	_	ADV	_	_	_	_	_	_
5	well	_	ADV	_	Degree=Pos	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	B	_	ADJ	_	Degree=Pos	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	TNF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	alpha	_	NOUN	_	Number=Sing	_	_	_	_
14	rapidly	_	ADV	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	translocation	_	NOUN	_	Number=Sing	_	_	_	_
18	primarily	_	ADV	_	_	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	p50-p65	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	NF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	precursors	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
9	kappa	_	VERB	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	alpha	_	PROPN	_	Number=Sing	_	_	_	_
12	became	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	strongly	_	ADV	_	_	_	_	_	_
14	phosphorylated	_	ADJ	_	Degree=Pos	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	same	_	ADJ	_	Degree=Pos	_	_	_	_
18	kinetics	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
6	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
7	after	_	ADP	_	_	_	_	_	_
8	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
13	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	revealed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	constitutively	_	ADV	_	_	_	_	_	_
21	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	p65	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
25	kappa	_	VERB	_	Number=Sing	_	_	_	_
26	B	_	PROPN	_	Number=Sing	_	_	_	_
27	alpha	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	accompanied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	processing	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	precursors	_	NOUN	_	Number=Plur	_	_	_	_
10	p100	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	p105	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	degradation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
18	kappa	_	VERB	_	Number=Sing	_	_	_	_
19	B	_	PROPN	_	Number=Sing	_	_	_	_
20	alpha	_	PROPN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	As	_	ADP	_	_	_	_	_	_
2	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vitro	_	NOUN	_	Number=Sing	_	_	_	_
5	model	_	NOUN	_	Number=Sing	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	p105	_	NOUN	_	Number=Sing	_	_	_	_
12	impedes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	ability	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	PROPN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	as	_	SCONJ	_	_	_	_	_	_
24	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	before	_	ADV	_	_	_	_	_	_
28	for	_	SCONJ	_	_	_	_	_	_
29	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
30	kappa	_	VERB	_	Number=Sing	_	_	_	_
31	B	_	PROPN	_	Number=Sing	_	_	_	_
32	alpha	_	PROPN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Surprisingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	even	_	ADV	_	_	_	_	_	_
4	p65	_	NUM	_	NumType=Card	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	but	_	CCONJ	_	_	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	c-rel	_	ADJ	_	Degree=Pos	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	vivo	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	TNF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	selectively	_	ADV	_	_	_	_	_	_
23	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	only	_	ADV	_	_	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	heteromers	_	NOUN	_	Number=Plur	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	that	_	SCONJ	_	_	_	_	_	_
33	modifications	_	NOUN	_	Number=Plur	_	_	_	_
34	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
35	not	_	ADV	_	_	_	_	_	_
36	only	_	ADV	_	_	_	_	_	_
37	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
38	kappa	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	B	_	NOUN	_	Number=Sing	_	_	_	_
40	molecules	_	NOUN	_	Number=Plur	_	_	_	_
41	but	_	CCONJ	_	_	_	_	_	_
42	also	_	ADV	_	_	_	_	_	_
43	NF	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	kappa	_	NOUN	_	Number=Sing	_	_	_	_
46	B	_	NOUN	_	Number=Sing	_	_	_	_
47	molecules	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	fact	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	cellular	_	ADJ	_	Number=Sing	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	binding	_	NOUN	_	Number=Sing	_	_	_	_
18	activity	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	p65-containing	_	ADJ	_	VerbForm=Ger	_	_	_	_
21	NF	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	vitro	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	hydrogen	_	NOUN	_	Number=Sing	_	_	_	_
10	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	translocation	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Rel	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	assumed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	triggered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
29	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
30	intermediates	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	also	_	ADV	_	_	_	_	_	_
33	coincided	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	incorporation	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	phosphate	_	NOUN	_	Number=Sing	_	_	_	_
38	into	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	same	_	ADJ	_	Degree=Pos	_	_	_	_
41	subunits	_	NOUN	_	Number=Plur	_	_	_	_
42	that	_	PRON	_	PronType=Rel	_	_	_	_
43	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
44	modified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
45	after	_	ADP	_	_	_	_	_	_
46	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
47	by	_	ADP	_	_	_	_	_	_
48	TNF	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	alpha	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
4	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	general	_	ADJ	_	Degree=Pos	_	_	_	_
9	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	vivo	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012944	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
4	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
5	proteins	_	NOUN	_	Number=Plur	_	_	_	_
6	that	_	PRON	_	PronType=Rel	_	_	_	_
7	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	negative	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	different	_	ADJ	_	Degree=Pos	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	independently	_	ADV	_	_	_	_	_	_
6	bound	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	neighboring	_	VERB	_	VerbForm=Ger	_	_	_	_
9	sequences	_	NOUN	_	Number=Plur	_	_	_	_
10	within	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	negative	_	ADJ	_	Degree=Pos	_	_	_	_
13	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	NRE	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
21	virus	_	NOUN	_	Number=Sing	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
34	extract	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	virus	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
40	human	_	ADJ	_	Degree=Pos	_	_	_	_
41	T	_	NOUN	_	Number=Sing	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	line	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	bound	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	novel	_	NOUN	_	Number=Sing	_	_	_	_
9	dyad	_	ADJ	_	Number=Sing	_	_	_	_
10	symmetrical	_	ADJ	_	Degree=Pos	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	sequence	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	well	_	ADV	_	Degree=Pos	_	_	_	_
5	conserved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	various	_	ADJ	_	Degree=Pos	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	isolates	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	partial	_	ADJ	_	Degree=Pos	_	_	_	_
14	homology	_	NOUN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	promoter	_	ADJ	_	Number=Sing	_	_	_	_
20	region	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	retinoblastoma	_	NOUN	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	DNA	_	NOUN	_	Number=Sing	_	_	_	_
3	binding	_	NOUN	_	Number=Sing	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	variety	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	virus	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	uninfected	_	ADJ	_	Degree=Pos	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	lines	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	means	_	NOUN	_	Number=Plur	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	gel	_	NOUN	_	Number=Sing	_	_	_	_
26	mobility	_	NOUN	_	Number=Sing	_	_	_	_
27	shift	_	NOUN	_	Number=Sing	_	_	_	_
28	assay	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	other	_	ADJ	_	Degree=Pos	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	bound	_	ADJ	_	Degree=Pos	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	putative	_	ADJ	_	Degree=Pos	_	_	_	_
8	AP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	recognition	_	NOUN	_	Number=Sing	_	_	_	_
12	sequence	_	NOUN	_	Number=Sing	_	_	_	_
13	predicted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	NRE	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	typical	_	ADJ	_	Degree=Pos	_	_	_	_
11	AP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	insertion	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
5	copies	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	former	_	ADJ	_	Degree=Pos	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	latter	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	into	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	heterologous	_	ADJ	_	Degree=Pos	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	reduced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	one	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	tenth	_	NOUN	_	Number=Sing	_	_	_	_
28	or	_	CCONJ	_	_	_	_	_	_
29	one	_	NUM	_	NumType=Card	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	third	_	ADJ	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	respectively	_	ADV	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	each	_	DET	_	_	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	may	_	AUX	_	VerbForm=Fin	_	_	_	_
6	function	_	VERB	_	VerbForm=Inf	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	novel	_	NOUN	_	Number=Sing	_	_	_	_
10	negative	_	ADJ	_	Degree=Pos	_	_	_	_
11	regulator	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012951	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	T	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	--	_	PUNCT	_	_	_	_	_	_
9	basic	_	ADJ	_	Degree=Pos	_	_	_	_
10	research	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
13	perspectives	_	NOUN	_	Number=Plur	_	_	_	_
14	for	_	ADP	_	_	_	_	_	_
15	gastroenterology	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Tissue	_	NOUN	_	Number=Sing	_	_	_	_
2	specific	_	ADJ	_	Degree=Pos	_	_	_	_
3	regulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factors	_	NOUN	_	Number=Plur	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	fascinating	_	ADJ	_	Degree=Pos	_	_	_	_
13	new	_	ADJ	_	Degree=Pos	_	_	_	_
14	field	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
17	immunology	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	review	_	NOUN	_	Number=Sing	_	_	_	_
3	summarizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	promoters	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	trans	_	NOUN	_	Number=Plur	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	acting	_	VERB	_	Number=Sing	_	_	_	_
17	factors	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	structural	_	ADJ	_	Degree=Pos	_	_	_	_
3	classes	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	basic	_	ADJ	_	Degree=Pos	_	_	_	_
11	methods	_	NOUN	_	Number=Plur	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	detection	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	analysis	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	factors	_	NOUN	_	Number=Plur	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	detailed	_	ADJ	_	Degree=Pos	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	most	_	ADV	_	_	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	trans	_	NOUN	_	Number=Plur	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	acting	_	VERB	_	Number=Sing	_	_	_	_
9	factors	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	T	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	e.g	_	X	_	_	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kB	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	AT	_	ADP	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	STAT	_	PROPN	_	Number=Sing	_	_	_	_
10	families	_	NOUN	_	Number=Plur	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	functional	_	ADJ	_	Degree=Pos	_	_	_	_
15	importance	_	NOUN	_	Number=Sing	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Several	_	ADJ	_	Degree=Pos	_	_	_	_
2	methods	_	NOUN	_	Number=Plur	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	down	_	ADP	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	regulation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	that	_	PRON	_	PronType=Dem	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	be	_	AUX	_	VerbForm=Inf	_	_	_	_
16	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	treatment	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	disease	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	regard	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
9	potential	_	ADJ	_	Degree=Pos	_	_	_	_
10	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
11	relevance	_	NOUN	_	Number=Sing	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	gastroenterology	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012957	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	E3	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcript	_	NOUN	_	Number=Sing	_	_	_	_
8	directly	_	ADV	_	_	_	_	_	_
9	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	retinoic	_	ADJ	_	Number=Sing	_	_	_	_
13	acid	_	NOUN	_	Number=Sing	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Retinoic	_	PROPN	_	Number=Sing	_	_	_	_
2	acid	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	RA	_	NOUN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	maturation	_	NOUN	_	Number=Sing	_	_	_	_
9	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
13	acid	_	NOUN	_	Number=Sing	_	_	_	_
14	receptor	_	NOUN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	RAR	_	PROPN	_	Number=Sing	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
22	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
25	development	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	differential	_	ADJ	_	Degree=Pos	_	_	_	_
5	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
6	analysis	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
10	library	_	NOUN	_	Number=Sing	_	_	_	_
11	constructed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	from	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	murine	_	NOUN	_	Number=Sing	_	_	_	_
15	RA	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	inducible	_	ADJ	_	Number=Sing	_	_	_	_
18	MPRO	_	NOUN	_	Number=Sing	_	_	_	_
19	promyelocyte	_	NOUN	_	Number=Sing	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	line	_	NOUN	_	Number=Sing	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
24	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	early	_	ADJ	_	Degree=Pos	_	_	_	_
27	genes	_	NOUN	_	Number=Plur	_	_	_	_
28	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	RA	_	PROPN	_	Number=Sing	_	_	_	_
31	during	_	ADP	_	_	_	_	_	_
32	granulocytic	_	ADJ	_	Degree=Pos	_	_	_	_
33	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	E3	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	one	_	NUM	_	NumType=Card	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	nine	_	NUM	_	NumType=Card	_	_	_	_
6	sequences	_	NOUN	_	Number=Plur	_	_	_	_
7	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	upregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	early	_	ADJ	_	Degree=Pos	_	_	_	_
16	manner	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	transcript	_	NOUN	_	Number=Sing	_	_	_	_
20	levels	_	NOUN	_	Number=Plur	_	_	_	_
21	peaking	_	VERB	_	VerbForm=Ger	_	_	_	_
22	after	_	ADP	_	_	_	_	_	_
23	60	_	NUM	_	NumType=Card	_	_	_	_
24	minutes	_	NOUN	_	Number=Plur	_	_	_	_
25	exposure	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	RA	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	E3	_	NUM	_	Number=Sing	_	_	_	_
2	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	RA	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	HL60	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	RA	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
18	subclone	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	HL60R	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	harbors	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	RAR	_	PROPN	_	Number=Sing	_	_	_	_
27	alpha	_	NOUN	_	Number=Sing	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	when	_	ADV	_	PronType=Int	_	_	_	_
4	HL60R	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	transduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	functional	_	ADJ	_	Degree=Pos	_	_	_	_
11	copy	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	RAR	_	PROPN	_	Number=Sing	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	RA	_	PROPN	_	Number=Sing	_	_	_	_
19	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	10	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	fold	_	NOUN	_	Number=Sing	_	_	_	_
24	increase	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	E3	_	NUM	_	Number=Sing	_	_	_	_
27	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
28	levels	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	E3	_	NOUN	_	Number=Sing	_	_	_	_
2	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	present	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	myeloid	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
15	lineages	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	absent	_	ADJ	_	Degree=Pos	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	nonhematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	encode	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	highly	_	ADV	_	_	_	_	_	_
26	hydrophobic	_	ADJ	_	Degree=Pos	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	potentially	_	ADV	_	_	_	_	_	_
29	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	polypeptide	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
33	function	_	NOUN	_	Number=Sing	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	significant	_	ADJ	_	Degree=Pos	_	_	_	_
36	homology	_	NOUN	_	Number=Sing	_	_	_	_
37	to	_	ADP	_	_	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	putative	_	ADJ	_	Degree=Pos	_	_	_	_
40	protein	_	NOUN	_	Number=Sing	_	_	_	_
41	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	murine	_	NOUN	_	Number=Sing	_	_	_	_
3	E3	_	PROPN	_	Number=Sing	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	harbors	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	single	_	ADJ	_	Degree=Pos	_	_	_	_
8	bipartite	_	ADJ	_	Degree=Pos	_	_	_	_
9	retinoic	_	ADJ	_	Number=Sing	_	_	_	_
10	acid	_	ADJ	_	Number=Sing	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	transient	_	ADJ	_	Degree=Pos	_	_	_	_
16	transfection	_	NOUN	_	Number=Sing	_	_	_	_
17	assays	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	conferred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	RA	_	NOUN	_	Number=Sing	_	_	_	_
20	sensitivity	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	E3	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
16	target	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	RAR	_	PROPN	_	Number=Sing	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	during	_	ADP	_	_	_	_	_	_
23	myelopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012963	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
2	through	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	lymphotoxin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	beta	_	NOUN	_	Number=Sing	_	_	_	_
7	receptor	_	NOUN	_	Number=Sing	_	_	_	_
8	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	HIV	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	replication	_	NOUN	_	Number=Sing	_	_	_	_
13	alone	_	ADJ	_	_	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	soluble	_	NOUN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	membrane	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	bound	_	ADJ	_	Degree=Pos	_	_	_	_
23	TNF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	alpha	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	level	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	ongoing	_	ADJ	_	Degree=Pos	_	_	_	_
5	HIV	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	replication	_	NOUN	_	Number=Sing	_	_	_	_
9	within	_	ADP	_	_	_	_	_	_
10	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	individual	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	critical	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	HIV	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Among	_	ADP	_	_	_	_	_	_
2	host	_	NOUN	_	Number=Sing	_	_	_	_
3	immune	_	ADJ	_	Number=Sing	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
8	TNF	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	previously	_	ADV	_	_	_	_	_	_
13	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
14	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
17	HIV	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	replication	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	various	_	ADJ	_	Degree=Pos	_	_	_	_
23	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	model	_	NOUN	_	Number=Sing	_	_	_	_
28	systems	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
7	through	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	TNF	_	PROPN	_	Number=Sing	_	_	_	_
10	receptor	_	PROPN	_	Number=Sing	_	_	_	_
11	family	_	NOUN	_	Number=Sing	_	_	_	_
12	member	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	lymphotoxin	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	beta	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	LT	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	beta	_	PROPN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	LT	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	betaR	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	also	_	ADV	_	_	_	_	_	_
31	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	HIV	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	replication	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	HIV	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	replication	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	cooperatively	_	ADV	_	_	_	_	_	_
9	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	when	_	ADV	_	PronType=Int	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
13	LT	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	betaR	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	TNF	_	PROPN	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	systems	_	NOUN	_	Number=Plur	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	simultaneously	_	ADV	_	_	_	_	_	_
22	engaged	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	ligands	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
6	coculture	_	NOUN	_	Number=Sing	_	_	_	_
7	cellular	_	ADJ	_	Number=Sing	_	_	_	_
8	assay	_	NOUN	_	Number=Sing	_	_	_	_
9	system	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	membrane	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	bound	_	ADJ	_	Degree=Pos	_	_	_	_
17	TNF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	LT	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	alpha1beta2	_	NOUN	_	Number=Sing	_	_	_	_
24	act	_	NOUN	_	Number=Sing	_	_	_	_
25	virtually	_	ADV	_	_	_	_	_	_
26	identically	_	ADV	_	_	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
29	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
30	forms	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	regulation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	HIV	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	replication	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cosignaling	_	VERB	_	VerbForm=Ger	_	_	_	_
4	via	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	LT	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	beta	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	TNF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	NOUN	_	Number=Sing	_	_	_	_
13	receptors	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	probably	_	ADV	_	_	_	_	_	_
16	involved	_	ADJ	_	Degree=Pos	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	modulation	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	HIV	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	replication	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	subsequent	_	ADJ	_	Degree=Pos	_	_	_	_
28	determination	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	HIV	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	1	_	NUM	_	NumType=Card	_	_	_	_
33	viral	_	ADJ	_	Degree=Pos	_	_	_	_
34	burden	_	NOUN	_	Number=Sing	_	_	_	_
35	in	_	ADP	_	_	_	_	_	_
36	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Intriguingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	surface	_	NOUN	_	Number=Sing	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	LT	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha1beta2	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	up	_	ADV	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	line	_	NOUN	_	Number=Sing	_	_	_	_
18	acutely	_	ADV	_	_	_	_	_	_
19	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	HIV	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	positive	_	ADJ	_	Degree=Pos	_	_	_	_
28	feedback	_	NOUN	_	Number=Sing	_	_	_	_
29	loop	_	NOUN	_	Number=Sing	_	_	_	_
30	between	_	ADP	_	_	_	_	_	_
31	HIV	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	infection	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	LT	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	alpha1beta2	_	NOUN	_	Number=Sing	_	_	_	_
39	expression	_	NOUN	_	Number=Sing	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	HIV	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	replication	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Given	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	critical	_	ADJ	_	Degree=Pos	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	LT	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	alpha1beta2	_	PROPN	_	Number=Sing	_	_	_	_
9	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
12	architecture	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
15	speculate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	LT	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha1beta2	_	NOUN	_	Number=Sing	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	involved	_	ADJ	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	HIV	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	abnormalities	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
31	organs	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012967	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Calcium	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	calmodulin-dependent	_	ADJ	_	Degree=Pos	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	kinase	_	NOUN	_	Number=Sing	_	_	_	_
6	II	_	NUM	_	NumType=Card	_	_	_	_
7	downregulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	both	_	CCONJ	_	_	_	_	_	_
9	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	protein	_	VERB	_	Number=Sing	_	_	_	_
12	kinase	_	NOUN	_	Number=Sing	_	_	_	_
13	C	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	VERB	_	Degree=Pos	_	_	_	_
16	pathways	_	NOUN	_	Number=Plur	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	cytokine	_	ADJ	_	Degree=Pos	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	human	_	ADJ	_	Degree=Pos	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Engagement	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	T	_	NOUN	_	Number=Sing	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	receptor	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	antigen	_	NOUN	_	Number=Sing	_	_	_	_
9	activates	_	NOUN	_	Number=Plur	_	_	_	_
10	phospholipase	_	NOUN	_	Number=Sing	_	_	_	_
11	C	_	NOUN	_	Number=Sing	_	_	_	_
12	resulting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	increase	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	free	_	ADJ	_	Degree=Pos	_	_	_	_
19	calcium	_	NOUN	_	Number=Sing	_	_	_	_
20	concentration	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	[	_	PUNCT	_	_	_	_	_	_
23	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
24	+	_	SYM	_	_	_	_	_	_
25	]	_	PUNCT	_	_	_	_	_	_
26	i	_	X	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	protein	_	NOUN	_	Number=Sing	_	_	_	_
32	kinase	_	NOUN	_	Number=Sing	_	_	_	_
33	C	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	PKC	_	PROPN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	[	_	PUNCT	_	_	_	_	_	_
3	Ca2	_	NOUN	_	Number=Sing	_	_	_	_
4	+	_	SYM	_	_	_	_	_	_
5	]	_	PUNCT	_	_	_	_	_	_
6	i	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	Ca2+/	_	PROPN	_	Number=Sing	_	_	_	_
9	calmodulin-dependent	_	ADJ	_	Degree=Pos	_	_	_	_
10	kinases	_	NOUN	_	Number=Plur	_	_	_	_
11	including	_	VERB	_	VerbForm=Ger	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	multifunctional	_	ADJ	_	Degree=Pos	_	_	_	_
14	Ca2+/	_	NOUN	_	Number=Sing	_	_	_	_
15	calmodulin-dependent	_	ADJ	_	Degree=Pos	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	kinase	_	NOUN	_	Number=Sing	_	_	_	_
18	II	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	CaM	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	K	_	PROPN	_	Number=Sing	_	_	_	_
23	II	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	as	_	ADV	_	_	_	_	_	_
27	well	_	ADV	_	Degree=Pos	_	_	_	_
28	as	_	ADP	_	_	_	_	_	_
29	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	type	_	NOUN	_	Number=Sing	_	_	_	_
33	2B	_	NOUN	_	Number=Sing	_	_	_	_
34	protein	_	NOUN	_	Number=Sing	_	_	_	_
35	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
6	as	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	key	_	ADJ	_	Degree=Pos	_	_	_	_
9	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	IL	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	4	_	NUM	_	NumType=Card	_	_	_	_
21	promoter	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	CaM	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	K	_	PROPN	_	Number=Sing	_	_	_	_
9	II	_	PROPN	_	NumType=Card	_	_	_	_
10	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	mutants	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	kinases	_	NOUN	_	Number=Plur	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	phosphatases	_	NOUN	_	Number=Plur	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	B*	_	PUNCT	_	Number=Sing	_	_	_	_
13	CaM	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	K	_	PROPN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	delta	_	PROPN	_	Number=Sing	_	_	_	_
18	CaM	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	AI	_	PROPN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	respectively	_	ADV	_	_	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	explore	_	VERB	_	VerbForm=Inf	_	_	_	_
26	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
27	relative	_	ADJ	_	Degree=Pos	_	_	_	_
28	role	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	cytokine	_	ADJ	_	Number=Sing	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	transcription	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
35	interactions	_	NOUN	_	Number=Plur	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	PKC	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
40	signaling	_	NOUN	_	Number=Sing	_	_	_	_
41	systems	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	gamma	_	NOUN	_	Number=Sing	_	_	_	_
2	B*CaM	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	K	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	delta	_	PROPN	_	Number=Sing	_	_	_	_
7	CaM	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	AI	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	exhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
14	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
15	Ca	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	2	_	NUM	_	NumType=Card	_	_	_	_
18	+)-	_	SYM	_	_	_	_	_	_
19	independent	_	ADJ	_	Degree=Pos	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	cotransfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	alone	_	ADJ	_	_	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	combination	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
32	T	_	PROPN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
37	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	intact	_	NOUN	_	Degree=Pos	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	2	_	NUM	_	NumType=Card	_	_	_	_
43	promoter	_	NOUN	_	Number=Sing	_	_	_	_
44	driving	_	VERB	_	VerbForm=Ger	_	_	_	_
45	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
46	expression	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
50	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
51	reporter	_	NOUN	_	Number=Sing	_	_	_	_
52	gene	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Cotransfection	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	B*	_	NOUN	_	Number=Sing	_	_	_	_
5	CaM	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	K	_	NOUN	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	construct	_	NOUN	_	Number=Sing	_	_	_	_
15	downregulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	ionomycin	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
26	myristate	_	NOUN	_	Number=Sing	_	_	_	_
27	acetate	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	PMA	_	PROPN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inhibitory	_	ADJ	_	Degree=Pos	_	_	_	_
3	effect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	CaM	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	K	_	PROPN	_	Number=Sing	_	_	_	_
8	II	_	NUM	_	NumType=Card	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
21	AP	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	AT	_	ADP	_	_	_	_	_	_
28	transactivating	_	NOUN	_	Number=Sing	_	_	_	_
29	pathways	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Under	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	same	_	ADJ	_	Degree=Pos	_	_	_	_
4	conditions	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	delta	_	PROPN	_	Number=Sing	_	_	_	_
7	CaM	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	AI	_	PROPN	_	Number=Sing	_	_	_	_
10	superinduced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	IL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	approximately	_	ADV	_	_	_	_	_	_
18	twofold	_	NOUN	_	Number=Sing	_	_	_	_
19	increase	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	both	_	DET	_	_	_	_	_	_
3	mutants	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	combination	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	gamma	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	*	_	PUNCT	_	_	_	_	_	_
12	CaM	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	K	_	PROPN	_	Number=Sing	_	_	_	_
15	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	delta	_	PROPN	_	Number=Sing	_	_	_	_
26	CaM	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	AI	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	when	_	ADV	_	PronType=Int	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	construct	_	NOUN	_	Number=Sing	_	_	_	_
8	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	also	_	ADV	_	_	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	gamma	_	NOUN	_	Number=Sing	_	_	_	_
2	B*	_	PUNCT	_	Number=Sing	_	_	_	_
3	CaM	_	PROPN	_	Number=Sing	_	_	_	_
4	-K	_	PROPN	_	Number=Sing	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	downregulated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	response	_	NOUN	_	Number=Sing	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	transfection	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	constitutively	_	ADV	_	_	_	_	_	_
20	active	_	ADJ	_	Degree=Pos	_	_	_	_
21	mutant	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	PKC	_	NOUN	_	Number=Sing	_	_	_	_
24	or	_	CCONJ	_	_	_	_	_	_
25	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	PMA	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CaM	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	K	_	PROPN	_	Number=Sing	_	_	_	_
8	II	_	PROPN	_	Number=Sing	_	_	_	_
9	may	_	AUX	_	VerbForm=Fin	_	_	_	_
10	exert	_	VERB	_	VerbForm=Inf	_	_	_	_
11	negative	_	ADJ	_	Degree=Pos	_	_	_	_
12	influences	_	NOUN	_	Number=Plur	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	cytokine	_	NOUN	_	Degree=Pos	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	T	_	NOUN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
24	preliminary	_	ADJ	_	Degree=Pos	_	_	_	_
25	evidence	_	NOUN	_	Number=Sing	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	negative	_	ADJ	_	Degree=Pos	_	_	_	_
28	cross	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	talk	_	NOUN	_	Number=Sing	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	PKC	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
39	signaling	_	NOUN	_	Number=Sing	_	_	_	_
40	systems	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012969	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	naive	_	ADJ	_	Degree=Pos	_	_	_	_
7	CD4	_	PROPN	_	Number=Sing	_	_	_	_
8	T	_	PROPN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	CD3	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	CD28	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	tropic	_	NOUN	_	Number=Sing	_	_	_	_
12	strain	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	HIV	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	LAI	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	replicate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	naive	_	ADJ	_	Degree=Pos	_	_	_	_
23	CD4	_	PROPN	_	Number=Sing	_	_	_	_
24	T	_	PROPN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	cross	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	linking	_	VERB	_	VerbForm=Ger	_	_	_	_
31	CD3	_	PROPN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	CD28	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	LAI	_	PROPN	_	Number=Sing	_	_	_	_
5	replicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	well	_	ADV	_	Degree=Pos	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	memory	_	NOUN	_	Number=Sing	_	_	_	_
9	CD4	_	PROPN	_	Number=Sing	_	_	_	_
10	T	_	PROPN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	same	_	ADJ	_	Degree=Pos	_	_	_	_
16	way	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Unlike	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	physiologically	_	ADV	_	_	_	_	_	_
4	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
5	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	PHA	_	NOUN	_	Number=Sing	_	_	_	_
8	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	productive	_	ADJ	_	Degree=Pos	_	_	_	_
10	LAI	_	NOUN	_	Number=Sing	_	_	_	_
11	replication	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	both	_	CCONJ	_	_	_	_	_	_
14	naive	_	ADJ	_	Degree=Pos	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	memory	_	NOUN	_	Number=Sing	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	conducted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	highly	_	ADV	_	_	_	_	_	_
7	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	FACS	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	subsets	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	CD4	_	PROPN	_	Number=Sing	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	identified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	both	_	CCONJ	_	_	_	_	_	_
23	CD45RA	_	PROPN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	CD62L	_	PROPN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Remixing	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	purified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	naive	_	ADJ	_	Degree=Pos	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
14	LAI	_	NOUN	_	Number=Sing	_	_	_	_
15	replication	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	memory	_	NOUN	_	Number=Sing	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	that	_	DET	_	_	_	_	_	_
22	memory	_	NOUN	_	Number=Sing	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	not	_	PART	_	_	_	_	_	_
27	restore	_	VERB	_	VerbForm=Inf	_	_	_	_
28	LAI	_	PROPN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	naive	_	ADJ	_	Degree=Pos	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	suppression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	productive	_	ADJ	_	Degree=Pos	_	_	_	_
5	LAI	_	NOUN	_	Number=Sing	_	_	_	_
6	replication	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	naive	_	ADJ	_	Degree=Pos	_	_	_	_
9	T	_	NOUN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	due	_	ADP	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	differential	_	ADJ	_	Degree=Pos	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	viral	_	ADJ	_	Degree=Pos	_	_	_	_
19	coreceptors	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	nor	_	CCONJ	_	_	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
24	due	_	ADP	_	_	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	important	_	ADJ	_	Degree=Pos	_	_	_	_
32	HIV	_	NOUN	_	Number=Sing	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	factors	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
37	factor	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	activator	_	NOUN	_	Number=Sing	_	_	_	_
42	protein	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	inherent	_	ADJ	_	Degree=Pos	_	_	_	_
3	resistance	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	naive	_	ADJ	_	Degree=Pos	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	productive	_	VERB	_	VerbForm=Inf	_	_	_	_
10	HIV	_	NOUN	_	Number=Sing	_	_	_	_
11	infection	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
17	advantage	_	NOUN	_	Number=Sing	_	_	_	_
18	as	_	SCONJ	_	_	_	_	_	_
19	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	here	_	ADV	_	PronType=Dem	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	sound	_	NOUN	_	Number=Sing	_	_	_	_
25	basis	_	NOUN	_	Number=Sing	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	proposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	clinical	_	ADJ	_	Degree=Pos	_	_	_	_
29	therapies	_	NOUN	_	Number=Plur	_	_	_	_
30	using	_	VERB	_	VerbForm=Ger	_	_	_	_
31	ex	_	NOUN	_	Number=Sing	_	_	_	_
32	vivo	_	NOUN	_	Number=Sing	_	_	_	_
33	expansion	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	reinfusion	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	CD4	_	NOUN	_	Number=Sing	_	_	_	_
38	T	_	NOUN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	from	_	ADP	_	_	_	_	_	_
41	HIV	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	adults	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012972	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	signal	_	NOUN	_	Number=Sing	_	_	_	_
5	transducer	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	STAT	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	signaling	_	NOUN	_	VerbForm=Ger	_	_	_	_
12	pathway	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	primary	_	ADJ	_	Degree=Pos	_	_	_	_
16	T	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Critical	_	ADJ	_	Degree=Pos	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	6	_	NUM	_	NumType=Card	_	_	_	_
7	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	T	_	NOUN	_	Number=Sing	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	initiated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	interaction	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	Ags	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	TCR	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	followed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
20	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
21	events	_	NOUN	_	Number=Plur	_	_	_	_
22	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	several	_	ADJ	_	Degree=Pos	_	_	_	_
27	genes	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	signal	_	NOUN	_	Number=Sing	_	_	_	_
5	transducer	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	activator	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	STAT	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	primary	_	ADJ	_	Degree=Pos	_	_	_	_
17	TCR	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	T	_	PROPN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	explored	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	purified	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
5	blood	_	NOUN	_	Number=Sing	_	_	_	_
6	T	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	STAT	_	NOUN	_	Number=Sing	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	approximately	_	ADV	_	_	_	_	_	_
15	3	_	NUM	_	NumType=Card	_	_	_	_
16	h	_	NOUN	_	Number=Plur	_	_	_	_
17	after	_	ADP	_	_	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	cross	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
24	Abs	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	STAT	_	NOUN	_	Number=Sing	_	_	_	_
3	proteins	_	NOUN	_	Number=Plur	_	_	_	_
4	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	by	_	SCONJ	_	_	_	_	_	_
7	using	_	VERB	_	VerbForm=Ger	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	IFN	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	GAS	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	related	_	ADJ	_	Degree=Pos	_	_	_	_
20	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
21	as	_	ADP	_	_	_	_	_	_
22	probes	_	NOUN	_	Number=Plur	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
25	mobility	_	NOUN	_	Number=Sing	_	_	_	_
26	shift	_	NOUN	_	Number=Sing	_	_	_	_
27	assay	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	extracts	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	anti-STAT	_	ADJ	_	Degree=Pos	_	_	_	_
8	Abs	_	NOUN	_	Number=Plur	_	_	_	_
9	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
12	contained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	STAT	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	3	_	NUM	_	NumType=Card	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	additional	_	ADJ	_	Degree=Pos	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	crossreactive	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	STAT	_	PROPN	_	Number=Sing	_	_	_	_
23	family	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	STAT	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	completely	_	ADV	_	_	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	pretreatment	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	either	_	CCONJ	_	_	_	_	_	_
13	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
16	A	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	thus	_	ADV	_	_	_	_	_	_
19	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	induction	_	NOUN	_	Number=Sing	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	due	_	ADP	_	_	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	secondary	_	ADJ	_	Degree=Pos	_	_	_	_
28	factor	_	NOUN	_	Number=Sing	_	_	_	_
29	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	by	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	T	_	NOUN	_	Number=Sing	_	_	_	_
34	cells	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	neutralizing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	anti-IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	6	_	NUM	_	NumType=Card	_	_	_	_
6	Abs	_	NOUN	_	Number=Plur	_	_	_	_
7	effectively	_	ADV	_	_	_	_	_	_
8	down	_	ADV	_	_	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	early	_	ADJ	_	Degree=Pos	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	STAT	_	PROPN	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	as	_	SCONJ	_	_	_	_	_	_
19	exogenously	_	ADV	_	_	_	_	_	_
20	added	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	6	_	NUM	_	NumType=Card	_	_	_	_
24	rapidly	_	ADV	_	_	_	_	_	_
25	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	DNA	_	PROPN	_	Number=Sing	_	_	_	_
27	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
28	similar	_	ADJ	_	Degree=Pos	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	TCR	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	bindings	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
36	can	_	AUX	_	VerbForm=Fin	_	_	_	_
37	be	_	AUX	_	VerbForm=Inf	_	_	_	_
38	concluded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	that	_	SCONJ	_	_	_	_	_	_
40	IL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	6	_	NUM	_	NumType=Card	_	_	_	_
43	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	factor	_	NOUN	_	Number=Sing	_	_	_	_
46	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
47	for	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	activation	_	NOUN	_	Number=Sing	_	_	_	_
50	of	_	ADP	_	_	_	_	_	_
51	STAT	_	PROPN	_	Number=Sing	_	_	_	_
52	proteins	_	NOUN	_	Number=Plur	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
55	primary	_	ADJ	_	Degree=Pos	_	_	_	_
56	T	_	NOUN	_	Number=Sing	_	_	_	_
57	cell	_	NOUN	_	Number=Sing	_	_	_	_
58	response	_	NOUN	_	Number=Sing	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012974	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Reversible	_	ADJ	_	Degree=Pos	_	_	_	_
2	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	monoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
6	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
7	U937	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	ML	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	9	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	myosin	_	ADJ	_	Number=Sing	_	_	_	_
18	light	_	NOUN	_	Number=Sing	_	_	_	_
19	chain	_	NOUN	_	Number=Sing	_	_	_	_
20	kinase	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	monoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	U937	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	differentiate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	into	_	ADP	_	_	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	various	_	ADJ	_	Degree=Pos	_	_	_	_
16	agents	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	1-(5	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	chloronaphthalene-1	_	NUM	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	sulfonyl	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1H-hexahydro-1,4-diazepine	_	NOUN	_	Number=Sing	_	_	_	_
13	hydrochloride	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	ML	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	9	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	myosin	_	ADJ	_	Number=Sing	_	_	_	_
24	light	_	NOUN	_	Number=Sing	_	_	_	_
25	chain	_	NOUN	_	Number=Sing	_	_	_	_
26	kinase	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	monocytoid	_	ADJ	_	Degree=Pos	_	_	_	_
32	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	lines	_	NOUN	_	Number=Plur	_	_	_	_
35	U937	_	NOUN	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	THP	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	but	_	CCONJ	_	_	_	_	_	_
41	not	_	ADV	_	_	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	myeloblastic	_	ADJ	_	Degree=Pos	_	_	_	_
44	leukemic	_	ADJ	_	Number=Sing	_	_	_	_
45	ML	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	cell	_	NOUN	_	Number=Sing	_	_	_	_
49	or	_	CCONJ	_	_	_	_	_	_
50	erythroleukemia	_	ADJ	_	Number=Sing	_	_	_	_
51	K562	_	NUM	_	Number=Sing	_	_	_	_
52	cells	_	NOUN	_	Number=Plur	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	further	_	ADV	_	_	_	_	_	_
8	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	effect	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	ML	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	9	_	NUM	_	NumType=Card	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	comparison	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	25	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dihydroxyvitamin	_	NOUN	_	Number=Sing	_	_	_	_
26	D3	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	VD3	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	typical	_	ADJ	_	Degree=Pos	_	_	_	_
32	inducer	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
35	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	ML	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	9	_	NUM	_	NumType=Card	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	nitroblue	_	ADJ	_	Number=Sing	_	_	_	_
6	tetrazolium	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	NBT	_	PROPN	_	Number=Sing	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	reducing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	U937	_	PROPN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	more	_	ADV	_	_	_	_	_	_
17	rapidly	_	ADV	_	_	_	_	_	_
18	than	_	ADP	_	_	_	_	_	_
19	VD3	_	NOUN	_	Number=Sing	_	_	_	_
20	:	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
3	marker	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	significantly	_	ADV	_	_	_	_	_	_
7	after	_	ADP	_	_	_	_	_	_
8	incubation	_	NOUN	_	Number=Sing	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	ML	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	9	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	VD3	_	NOUN	_	Number=Sing	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	4	_	NUM	_	NumType=Card	_	_	_	_
17	hours	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	day	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	respectively	_	ADV	_	_	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	ML	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	9	_	NUM	_	NumType=Card	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	alpha	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	naphthyl	_	ADJ	_	Number=Sing	_	_	_	_
9	acetate	_	NOUN	_	Number=Sing	_	_	_	_
10	esterase	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	ANAE	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	another	_	DET	_	_	_	_	_	_
17	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
18	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
19	marker	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	more	_	ADV	_	_	_	_	_	_
22	rapidly	_	ADV	_	_	_	_	_	_
23	than	_	ADP	_	_	_	_	_	_
24	VD3	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	maximum	_	ADJ	_	Degree=Pos	_	_	_	_
3	levels	_	NOUN	_	Number=Plur	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	markers	_	NOUN	_	Number=Plur	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	ML	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	9	_	NUM	_	NumType=Card	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
16	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	VD3	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	after	_	ADP	_	_	_	_	_	_
22	removal	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	ML	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	9	_	NUM	_	NumType=Card	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	medium	_	NOUN	_	Number=Sing	_	_	_	_
30	by	_	SCONJ	_	_	_	_	_	_
31	washing	_	VERB	_	VerbForm=Ger	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	expressions	_	NOUN	_	Number=Plur	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	theses	_	NOUN	_	Number=Plur|PronType=Dem	_	_	_	_
39	markers	_	NOUN	_	Number=Plur	_	_	_	_
40	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	within	_	ADP	_	_	_	_	_	_
42	4	_	NUM	_	NumType=Card	_	_	_	_
43	hours	_	NOUN	_	Number=Plur	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	reached	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	basal	_	ADJ	_	Degree=Pos	_	_	_	_
47	levels	_	NOUN	_	Number=Plur	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	1	_	NUM	_	NumType=Card	_	_	_	_
50	day	_	NOUN	_	Number=Sing	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
53	that	_	SCONJ	_	_	_	_	_	_
54	ML	_	NOUN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	9's	_	NOUN	_	Number=Plur	_	_	_	_
57	induction	_	NOUN	_	Number=Sing	_	_	_	_
58	of	_	ADP	_	_	_	_	_	_
59	expression	_	NOUN	_	Number=Sing	_	_	_	_
60	of	_	ADP	_	_	_	_	_	_
61	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
62	-	_	PUNCT	_	_	_	_	_	_
63	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
64	phenotypes	_	NOUN	_	Number=Plur	_	_	_	_
65	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
66	reversible	_	ADJ	_	Degree=Pos	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	growth	_	NOUN	_	Number=Sing	_	_	_	_
3	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	U937	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	ML	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	9	_	NUM	_	NumType=Card	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	also	_	ADV	_	_	_	_	_	_
13	reversible	_	ADJ	_	Degree=Pos	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	another	_	DET	_	_	_	_	_	_
7	line	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	monoblastic	_	ADJ	_	Degree=Pos	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	THP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	ML	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	9	_	NUM	_	NumType=Card	_	_	_	_
4	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	little	_	ADJ	_	Degree=Pos	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	no	_	DET	_	_	_	_	_	_
8	effect	_	NOUN	_	Number=Sing	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	morphology	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	U937	_	NUM	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	but	_	CCONJ	_	_	_	_	_	_
16	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
23	lineage	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	surface	_	NOUN	_	Number=Sing	_	_	_	_
27	antigen	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	CD14	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	some	_	DET	_	_	_	_	_	_
33	extent	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Irreversible	_	ADJ	_	Degree=Pos	_	_	_	_
2	terminal	_	NOUN	_	Degree=Pos	_	_	_	_
3	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
4	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	VD3	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	down	_	ADP	_	_	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	c-myc	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	upregulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	c	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	fos	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	ML	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	9	_	NUM	_	NumType=Card	_	_	_	_
33	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	not	_	PART	_	_	_	_	_	_
35	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	expression	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
40	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
41	appreciably	_	ADV	_	_	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	ML	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	9-induced	_	VERB	_	Degree=Pos	_	_	_	_
4	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	also	_	ADV	_	_	_	_	_	_
7	reversible	_	ADJ	_	Degree=Pos	_	_	_	_
8	when	_	ADV	_	PronType=Int	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	cultured	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	cultured	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	ML	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	9	_	NUM	_	NumType=Card	_	_	_	_
19	plus	_	CCONJ	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	anti-cancer	_	NOUN	_	Degree=Pos	_	_	_	_
22	drug	_	NOUN	_	Number=Sing	_	_	_	_
23	such	_	ADJ	_	Degree=Pos	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	beta	_	NOUN	_	Number=Sing	_	_	_	_
28	-D	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	arabino	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	furanosylcytosine	_	NOUN	_	Number=Sing	_	_	_	_
33	or	_	CCONJ	_	_	_	_	_	_
34	daunomycin	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	became	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	irreversible	_	ADJ	_	Degree=Pos	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	however	_	ADV	_	_	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	upon	_	ADP	_	_	_	_	_	_
8	simultaneous	_	ADJ	_	Degree=Pos	_	_	_	_
9	treatment	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
14	growth	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	beta	_	NOUN	_	Number=Sing	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	TGF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	beta	_	NOUN	_	Number=Sing	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	which	_	PRON	_	PronType=Rel	_	_	_	_
27	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	not	_	PART	_	_	_	_	_	_
29	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
30	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	U937	_	NUM	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	but	_	CCONJ	_	_	_	_	_	_
35	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
36	growth	_	NOUN	_	Number=Sing	_	_	_	_
37	arrest	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	G0	_	NOUN	_	Number=Sing	_	_	_	_
44	/	_	PUNCT	_	_	_	_	_	_
45	G1	_	NOUN	_	Number=Sing	_	_	_	_
46	phase	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	cell	_	NOUN	_	Number=Sing	_	_	_	_
50	cycle	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	ML	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	9	_	NUM	_	NumType=Card	_	_	_	_
8	should	_	AUX	_	VerbForm=Fin	_	_	_	_
9	be	_	AUX	_	VerbForm=Inf	_	_	_	_
10	useful	_	ADJ	_	Degree=Pos	_	_	_	_
11	for	_	SCONJ	_	_	_	_	_	_
12	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
17	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012976	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	GATA	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
6	cooperate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	promote	_	VERB	_	VerbForm=Inf	_	_	_	_
9	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	survival	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
14	bcl	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	xL	_	NOUN	_	Number=Sing	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	GATA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	essential	_	ADJ	_	Degree=Pos	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	normal	_	ADJ	_	Degree=Pos	_	_	_	_
11	erythropoiesis	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	examining	_	VERB	_	VerbForm=Ger	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	vitro	_	ADJ	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
7	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
8	stem	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
12	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	previously	_	ADV	_	_	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	absence	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	GATA	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	committed	_	VERB	_	Degree=Pos	_	_	_	_
24	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
25	precursors	_	NOUN	_	Number=Plur	_	_	_	_
26	fail	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	complete	_	VERB	_	Degree=Pos	_	_	_	_
29	maturation	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	instead	_	ADV	_	_	_	_	_	_
32	undergo	_	VERB	_	VerbForm=Inf	_	_	_	_
33	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
3	by	_	ADP	_	_	_	_	_	_
4	which	_	PRON	_	PronType=Rel	_	_	_	_
5	GATA	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	controls	_	NOUN	_	Number=Plur	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	survival	_	NOUN	_	Number=Sing	_	_	_	_
11	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	unknown	_	ADJ	_	Degree=Pos	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	GATA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	strongly	_	ADV	_	_	_	_	_	_
13	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	anti-apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	bcl	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	xL	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	not	_	ADV	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	related	_	ADJ	_	Degree=Pos	_	_	_	_
28	proteins	_	NOUN	_	Number=Plur	_	_	_	_
29	bcl	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	mcl	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	1	_	NUM	_	NumType=Card	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	bcl	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	xL	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	SCONJ	_	_	_	_	_	_
10	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
11	GATA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	survival	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	vitro	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	differentiated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
24	bcl	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	xL	_	NOUN	_	Number=Sing	_	_	_	_
27	-/-	_	PUNCT	_	_	_	_	_	_
28	embryonic	_	ADJ	_	Degree=Pos	_	_	_	_
29	stem	_	NOUN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	fail	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
32	to	_	PART	_	_	_	_	_	_
33	generate	_	VERB	_	VerbForm=Inf	_	_	_	_
34	viable	_	ADJ	_	Degree=Pos	_	_	_	_
35	mature	_	ADJ	_	Degree=Pos	_	_	_	_
36	definitive	_	ADJ	_	Degree=Pos	_	_	_	_
37	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
41	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
42	resembling	_	VERB	_	VerbForm=Ger	_	_	_	_
43	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	GATA	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	gene	_	NOUN	_	Number=Sing	_	_	_	_
49	disruption	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	which	_	PRON	_	PronType=Rel	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	also	_	ADV	_	_	_	_	_	_
12	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	survival	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	cooperates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	GATA	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	to	_	PART	_	_	_	_	_	_
24	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
25	bcl	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	xL	_	ADJ	_	Degree=Pos	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	maintain	_	VERB	_	VerbForm=Inf	_	_	_	_
33	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
34	cell	_	NOUN	_	Number=Sing	_	_	_	_
35	viability	_	NOUN	_	Number=Sing	_	_	_	_
36	during	_	ADP	_	_	_	_	_	_
37	terminal	_	NOUN	_	Number=Sing	_	_	_	_
38	maturation	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Together	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	data	_	NOUN	_	Number=Sing	_	_	_	_
5	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	bcl	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	xL	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	essential	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	normal	_	ADJ	_	Degree=Pos	_	_	_	_
14	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
15	development	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	suggest	_	VERB	_	VerbForm=Inf	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
20	hierarchy	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	bcl	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	xL	_	PROPN	_	Number=Sing	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	critical	_	ADJ	_	Degree=Pos	_	_	_	_
29	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
30	effector	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	GATA	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
39	signals	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012981	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Estrogen	_	NOUN	_	Number=Sing	_	_	_	_
2	receptor	_	NOUN	_	Number=Sing	_	_	_	_
3	diminishes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	DNA	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	activities	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	chicken	_	NOUN	_	Number=Sing	_	_	_	_
10	GATA	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	CACCC	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	binding	_	NOUN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	estrogen	_	NOUN	_	Number=Sing	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	ER	_	NOUN	_	Number=Sing	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	repressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
9	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	effect	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	ER	_	PROPN	_	Number=Sing	_	_	_	_
11	alpha	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	referred	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	throughout	_	ADP	_	_	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	ER	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	DNA	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	binding	_	VERB	_	Number=Sing	_	_	_	_
23	activities	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	factors	_	NOUN	_	Number=Plur	_	_	_	_
27	involved	_	ADJ	_	Degree=Pos	_	_	_	_
28	in	_	SCONJ	_	_	_	_	_	_
29	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	specific	_	ADJ	_	Degree=Pos	_	_	_	_
36	genes	_	NOUN	_	Number=Plur	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	particular	_	ADJ	_	Degree=Pos	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	histone	_	NOUN	_	Number=Sing	_	_	_	_
45	H5	_	NOUN	_	Number=Sing	_	_	_	_
46	gene	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	presence	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	rabbit	_	NOUN	_	Number=Sing	_	_	_	_
15	reticulocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	lysate	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	human	_	ADJ	_	Degree=Pos	_	_	_	_
19	ER	_	NOUN	_	Number=Sing	_	_	_	_
20	reduced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	activities	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	chicken	_	NOUN	_	Number=Sing	_	_	_	_
26	immature	_	NOUN	_	Degree=Pos	_	_	_	_
27	erythrocyte	_	NOUN	_	Number=Sing	_	_	_	_
28	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
29	extracted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	proteins	_	NOUN	_	Number=Plur	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	GATA	_	PROPN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	CACCC	_	NOUN	_	Number=Sing	_	_	_	_
35	sites	_	NOUN	_	Number=Plur	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	H5	_	NOUN	_	Number=Sing	_	_	_	_
39	promoter	_	NOUN	_	Number=Sing	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	activities	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	NF1	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	not	_	PART	_	_	_	_	_	_
13	affected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	ER	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	ER	_	NOUN	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	estrogen	_	NOUN	_	Degree=Pos	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	element	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	addition	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	rabbit	_	NOUN	_	Number=Sing	_	_	_	_
15	reticulocyte	_	NOUN	_	Number=Sing	_	_	_	_
16	lysate	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	lysate	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
6	for	_	SCONJ	_	_	_	_	_	_
7	ER	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	diminish	_	VERB	_	VerbForm=Inf	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	GATA	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	additional	_	ADJ	_	Degree=Pos	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	s	_	X	_	_	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	full	_	ADJ	_	Degree=Pos	_	_	_	_
14	ER	_	NOUN	_	Number=Sing	_	_	_	_
15	function	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	GATA	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	CACCC	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	critical	_	ADJ	_	Degree=Pos	_	_	_	_
12	for	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	developmentally	_	ADV	_	_	_	_	_	_
15	regulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	specific	_	ADJ	_	Degree=Pos	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	hypothesize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	DET	_	_	_	_	_	_
4	interference	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	activities	_	NOUN	_	Number=Plur	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	GATA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	CACCC	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	ER	_	NOUN	_	Number=Sing	_	_	_	_
26	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	regulation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
30	genes	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012984	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	requirements	_	NOUN	_	Number=Plur	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	U2	_	PROPN	_	Number=Sing	_	_	_	_
6	snRNA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	B	_	ADJ	_	Degree=Pos	_	_	_	_
13	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	U2	_	PROPN	_	Number=Sing	_	_	_	_
6	small	_	ADJ	_	Degree=Pos	_	_	_	_
7	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
8	RNA	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	snRNA	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	distal	_	ADJ	_	Degree=Pos	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	element	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	one	_	NUM	_	NumType=Card	_	_	_	_
29	octamer	_	NOUN	_	Number=Sing	_	_	_	_
30	motif	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	Oct	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	three	_	NUM	_	NumType=Card	_	_	_	_
36	Sp	_	NOUN	_	Number=Sing	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	binding	_	NOUN	_	Number=Sing	_	_	_	_
40	sites	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	study	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	requirement	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	B	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	different	_	ADJ	_	Degree=Pos	_	_	_	_
13	U2	_	PROPN	_	Number=Sing	_	_	_	_
14	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
15	constructions	_	NOUN	_	Number=Plur	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	into	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	line	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	BJA	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	B	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	U2	_	PROPN	_	Number=Sing	_	_	_	_
9	snRNA	_	PROPN	_	Number=Sing	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	also	_	ADV	_	_	_	_	_	_
16	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
19	comprising	_	VERB	_	VerbForm=Ger	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	Oct	_	PROPN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	at	_	ADV	_	_	_	_	_	_
25	least	_	ADV	_	Degree=Sup	_	_	_	_
26	one	_	NUM	_	NumType=Card	_	_	_	_
27	Sp	_	NOUN	_	Number=Sing	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	binding	_	NOUN	_	Number=Sing	_	_	_	_
31	site	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Deletion	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	all	_	DET	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	Sp	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	sites	_	NOUN	_	Number=Plur	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
13	reduces	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	80	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	90	_	NUM	_	NumType=Card	_	_	_	_
19	%	_	SYM	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	as	_	ADV	_	_	_	_	_	_
24	well	_	ADV	_	Degree=Pos	_	_	_	_
25	as	_	ADP	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	BJA	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	B	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	whereas	_	SCONJ	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	removal	_	NOUN	_	Number=Sing	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	octamer	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	binding	_	VERB	_	Number=Sing	_	_	_	_
40	site	_	NOUN	_	Number=Sing	_	_	_	_
41	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
42	transcription	_	NOUN	_	Number=Sing	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	levels	_	NOUN	_	Number=Plur	_	_	_	_
45	below	_	ADP	_	_	_	_	_	_
46	detection	_	NOUN	_	Number=Sing	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	both	_	DET	_	_	_	_	_	_
49	cell	_	NOUN	_	Number=Sing	_	_	_	_
50	types	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Enhancers	_	NOUN	_	Number=Plur	_	_	_	_
2	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	single	_	NOUN	_	Degree=Pos	_	_	_	_

1	Oct	_	PROPN	_	_	_	_	_	_
2	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	nevertheless	_	ADV	_	_	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	capacity	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	partially	_	ADV	_	_	_	_	_	_
10	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	U2	_	PROPN	_	Number=Sing	_	_	_	_
12	snRNA	_	PROPN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	both	_	CCONJ	_	_	_	_	_	_
16	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	which	_	PRON	_	PronType=Rel	_	_	_	_
21	only	_	ADV	_	_	_	_	_	_
22	OTF	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	BJA	_	PROPN	_	Number=Sing	_	_	_	_
31	-B	_	NOUN	_	Number=Sing	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	which	_	PRON	_	PronType=Rel	_	_	_	_
35	OTF	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	2	_	NUM	_	NumType=Card	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	predominantly	_	ADV	_	_	_	_	_	_
41	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	octamer	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	binding	_	NOUN	_	Number=Sing	_	_	_	_
45	factor	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	most	_	ADV	_	_	_	_	_	_
3	likely	_	ADJ	_	Degree=Pos	_	_	_	_
4	interpretation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
7	results	_	NOUN	_	Number=Plur	_	_	_	_
8	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	both	_	CCONJ	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	OTF	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	B-cell	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	OTF	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	can	_	AUX	_	VerbForm=Fin	_	_	_	_
33	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
34	U2	_	PROPN	_	Number=Sing	_	_	_	_
35	snRNA	_	PROPN	_	Number=Sing	_	_	_	_
36	transcription	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	also	_	ADV	_	_	_	_	_	_
4	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	similar	_	ADJ	_	Degree=Pos	_	_	_	_
7	functional	_	ADJ	_	Degree=Pos	_	_	_	_
8	cooperation	_	NOUN	_	Number=Sing	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	Oct	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	adjacent	_	ADJ	_	Degree=Pos	_	_	_	_
21	Sp	_	NOUN	_	Number=Sing	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	BJA	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	B	_	PROPN	_	Number=Sing	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	as	_	SCONJ	_	_	_	_	_	_
33	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
35	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	since	_	ADP	_	_	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	template	_	NOUN	_	Number=Sing	_	_	_	_
43	which	_	PRON	_	PronType=Rel	_	_	_	_
44	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
46	weak	_	ADJ	_	Degree=Pos	_	_	_	_
47	binding	_	NOUN	_	Number=Sing	_	_	_	_
48	site	_	NOUN	_	Number=Sing	_	_	_	_
49	for	_	ADP	_	_	_	_	_	_
50	OTFs	_	NOUN	_	Number=Plur	_	_	_	_
51	expresses	_	VERB	_	Number=Plur	_	_	_	_
52	wild	_	ADJ	_	Degree=Pos	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	type	_	NOUN	_	Number=Sing	_	_	_	_
55	levels	_	NOUN	_	Number=Plur	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	U2	_	PROPN	_	Number=Sing	_	_	_	_
58	snRNA	_	NOUN	_	Number=Sing	_	_	_	_
59	in	_	ADP	_	_	_	_	_	_
60	both	_	DET	_	_	_	_	_	_
61	cell	_	NOUN	_	Number=Sing	_	_	_	_
62	types	_	NOUN	_	Number=Plur	_	_	_	_
63	when	_	ADV	_	PronType=Int	_	_	_	_
64	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
65	weak	_	ADJ	_	Degree=Pos	_	_	_	_
66	octamer	_	NOUN	_	Number=Sing	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	binding	_	NOUN	_	Number=Sing	_	_	_	_
69	site	_	NOUN	_	Number=Sing	_	_	_	_
70	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
71	combined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
72	with	_	ADP	_	_	_	_	_	_
73	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
74	Sp	_	NOUN	_	Number=Sing	_	_	_	_
75	1	_	NUM	_	NumType=Card	_	_	_	_
76	-	_	PUNCT	_	_	_	_	_	_
77	binding	_	NOUN	_	Number=Sing	_	_	_	_
78	site	_	NOUN	_	Number=Sing	_	_	_	_
79	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012991	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Unexpected	_	ADJ	_	Degree=Pos	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	coordinated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Spi-1	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	Fli	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
14	genes	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	four	_	NUM	_	NumType=Card	_	_	_	_
17	Epo	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	lines	_	NOUN	_	Number=Plur	_	_	_	_
22	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	from	_	ADP	_	_	_	_	_	_
24	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
25	mice	_	NOUN	_	Number=Plur	_	_	_	_
26	displaying	_	VERB	_	VerbForm=Ger	_	_	_	_
27	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	specific	_	ADJ	_	Degree=Pos	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	thermosensitive	_	ADJ	_	Degree=Pos	_	_	_	_
34	SV40	_	NOUN	_	Number=Sing	_	_	_	_
35	T	_	NOUN	_	Number=Sing	_	_	_	_
36	antigen	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Most	_	ADJ	_	_	_	_	_	_
2	erythroleukemic	_	ADJ	_	Degree=Pos	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	vitro	_	NOUN	_	Number=Sing	_	_	_	_
8	coexpress	_	NOUN	_	Number=Sing	_	_	_	_
9	erythrocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
12	markers	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	often	_	ADV	_	_	_	_	_	_
15	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	Spi	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	/	_	PUNCT	_	_	_	_	_	_
25	or	_	CCONJ	_	_	_	_	_	_
26	Fli	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factors	_	NOUN	_	Number=Plur	_	_	_	_
31	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	as	_	ADP	_	_	_	_	_	_
33	transactivators	_	NOUN	_	Number=Plur	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	megakaryocyte	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	specific	_	ADJ	_	Degree=Pos	_	_	_	_
38	promoters	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	possibility	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	SCONJ	_	_	_	_	_	_
11	establishing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	new	_	ADJ	_	Degree=Pos	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	lines	_	NOUN	_	Number=Plur	_	_	_	_
15	keeping	_	VERB	_	VerbForm=Ger	_	_	_	_
16	strictly	_	ADV	_	_	_	_	_	_
17	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	properties	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	vitro	_	NOUN	_	Number=Sing	_	_	_	_
23	through	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	conditional	_	ADJ	_	Degree=Pos	_	_	_	_
28	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	erythrocytic	_	ADJ	_	Degree=Pos	_	_	_	_
31	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	purpose	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	established	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	several	_	ADJ	_	Degree=Pos	_	_	_	_
8	lines	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
11	mice	_	NOUN	_	Number=Plur	_	_	_	_
12	displaying	_	VERB	_	VerbForm=Ger	_	_	_	_
13	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	specific	_	ADJ	_	Degree=Pos	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	thermosensitive	_	ADJ	_	Degree=Pos	_	_	_	_
20	SV40	_	NOUN	_	Number=Sing	_	_	_	_
21	T	_	NOUN	_	Number=Sing	_	_	_	_
22	antigen	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	As	_	SCONJ	_	_	_	_	_	_
2	expected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
6	mice	_	NOUN	_	Number=Plur	_	_	_	_
7	developed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	splenomegaly	_	NOUN	_	Number=Sing	_	_	_	_
9	due	_	ADP	_	_	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	massive	_	ADJ	_	Degree=Pos	_	_	_	_
13	amplification	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	Ter	_	PROPN	_	Number=Sing	_	_	_	_
16	119	_	NUM	_	NumType=Card	_	_	_	_
17	positive	_	ADJ	_	Degree=Pos	_	_	_	_
18	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
19	nucleated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	antigen	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Despite	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	drastic	_	ADJ	_	Degree=Pos	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	vivo	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vitro	_	ADJ	_	Degree=Pos	_	_	_	_
11	immortalization	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
16	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
17	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
18	unexpectedly	_	ADV	_	_	_	_	_	_
19	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	at	_	ADP	_	_	_	_	_	_
21	low	_	ADJ	_	Degree=Pos	_	_	_	_
22	frequency	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	all	_	DET	_	_	_	_	_	_
26	four	_	NUM	_	NumType=Card	_	_	_	_
27	cell	_	NOUN	_	Number=Sing	_	_	_	_
28	lines	_	NOUN	_	Number=Plur	_	_	_	_
29	established	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	both	_	CCONJ	_	_	_	_	_	_
32	erythrocytic	_	ADJ	_	Number=Sing	_	_	_	_
33	(	_	PUNCT	_	_	_	_	_	_
34	globins	_	NOUN	_	Number=Plur	_	_	_	_
35	)	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
38	markers	_	NOUN	_	Number=Plur	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
41	IIb	_	NOUN	_	Number=Sing	_	_	_	_
42	,	_	PUNCT	_	_	_	_	_	_
43	platelet	_	NOUN	_	Number=Sing	_	_	_	_
44	factor	_	NOUN	_	Number=Sing	_	_	_	_
45	4	_	NUM	_	NumType=Card	_	_	_	_
46	)	_	PUNCT	_	_	_	_	_	_
47	as	_	ADV	_	_	_	_	_	_
48	well	_	ADV	_	Degree=Pos	_	_	_	_
49	as	_	ADP	_	_	_	_	_	_
50	Spi	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	1	_	NUM	_	NumType=Card	_	_	_	_
53	and	_	CCONJ	_	_	_	_	_	_
54	Fli	_	PROPN	_	Number=Sing	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	1	_	NUM	_	NumType=Card	_	_	_	_
57	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
58	at	_	ADP	_	_	_	_	_	_
59	permissive	_	ADJ	_	Degree=Pos	_	_	_	_
60	temperature	_	NOUN	_	Number=Sing	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	Switching	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	nonpermissive	_	ADJ	_	Degree=Pos	_	_	_	_
7	temperature	_	NOUN	_	Number=Sing	_	_	_	_
8	led	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	increase	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	globin	_	ADJ	_	Degree=Pos	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	concomitant	_	ADJ	_	Degree=Pos	_	_	_	_
19	decrease	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	Spi-1	_	PROPN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	Fli	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
31	genes	_	NOUN	_	Number=Plur	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	erythropoietin	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
37	manner	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Spi-1	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Fli	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	already	_	ADV	_	_	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	Ter	_	PROPN	_	Number=Sing	_	_	_	_
18	119	_	NUM	_	NumType=Card	_	_	_	_
19	positive	_	ADJ	_	Degree=Pos	_	_	_	_
20	cell	_	NOUN	_	Number=Sing	_	_	_	_
21	population	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
24	mice	_	NOUN	_	Number=Plur	_	_	_	_
25	spleen	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	vivo	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	like	_	ADP	_	_	_	_	_	_
4	normal	_	ADJ	_	Degree=Pos	_	_	_	_
5	Ter	_	PROPN	_	Number=Sing	_	_	_	_
6	119	_	NUM	_	NumType=Card	_	_	_	_
7	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	Ter	_	NOUN	_	Number=Sing	_	_	_	_
12	119	_	NUM	_	NumType=Card	_	_	_	_
13	positive	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
17	mice	_	NOUN	_	Number=Plur	_	_	_	_
18	still	_	ADV	_	_	_	_	_	_
19	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	high	_	ADJ	_	Degree=Pos	_	_	_	_
21	levels	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	beta	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	globin	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	very	_	ADV	_	_	_	_	_	_
28	low	_	ADJ	_	Degree=Pos	_	_	_	_
29	or	_	CCONJ	_	_	_	_	_	_
30	undetectable	_	ADJ	_	Degree=Pos	_	_	_	_
31	glycoprotein	_	NOUN	_	Number=Sing	_	_	_	_
32	IIb	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	platelet	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	4	_	NUM	_	NumType=Card	_	_	_	_
37	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
38	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	unexpected	_	ADJ	_	Degree=Pos	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	megakaryocytic	_	ADJ	_	Degree=Pos	_	_	_	_
13	genes	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	property	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	immortalized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	can	_	AUX	_	VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	be	_	AUX	_	VerbForm=Inf	_	_	_	_
25	explained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	only	_	ADV	_	_	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	Spi	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	1	_	NUM	_	NumType=Card	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	/	_	PUNCT	_	_	_	_	_	_
36	or	_	CCONJ	_	_	_	_	_	_
37	Fli	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	1	_	NUM	_	NumType=Card	_	_	_	_
40	genes	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012995	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	EBF	_	PROPN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	E47	_	PROPN	_	Number=Sing	_	_	_	_
4	collaborate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
11	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
12	surrogate	_	ADJ	_	Number=Sing	_	_	_	_
13	light	_	NOUN	_	Number=Sing	_	_	_	_
14	chain	_	NOUN	_	Number=Sing	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Early	_	ADJ	_	Degree=Pos	_	_	_	_
2	B	_	ADJ	_	Degree=Pos	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	EBF	_	PROPN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	E47	_	PROPN	_	Number=Sing	_	_	_	_
10	participate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
14	control	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	early	_	ADJ	_	Degree=Pos	_	_	_	_
17	B	_	ADJ	_	Degree=Pos	_	_	_	_
18	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	With	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	aim	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	SCONJ	_	_	_	_	_	_
5	identifying	_	VERB	_	VerbForm=Ger	_	_	_	_
6	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
7	targets	_	NOUN	_	Number=Plur	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	factors	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	stably	_	ADV	_	_	_	_	_	_
15	transfected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	cDNAs	_	NOUN	_	Number=Plur	_	_	_	_
17	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
18	EBF	_	PROPN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	covalent	_	ADJ	_	Degree=Pos	_	_	_	_
22	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	E47	_	NUM	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	individually	_	ADV	_	_	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	together	_	ADV	_	_	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	into	_	ADP	_	_	_	_	_	_
31	immature	_	ADJ	_	Degree=Pos	_	_	_	_
32	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
33	Ba	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	F3	_	NOUN	_	Number=Sing	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	which	_	PRON	_	PronType=Rel	_	_	_	_
39	lack	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
40	both	_	DET	_	_	_	_	_	_
41	factors	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	combination	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	EBF	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	E47	_	PROPN	_	Number=Sing	_	_	_	_
7	induce	_	VERB	_	_	_	_	_	_
8	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
13	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
14	surrogate	_	ADJ	_	Number=Sing	_	_	_	_
15	light	_	NOUN	_	Number=Sing	_	_	_	_
16	chain	_	NOUN	_	Number=Sing	_	_	_	_
17	genes	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	lambda5	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	VpreB	_	PROPN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	whereas	_	SCONJ	_	_	_	_	_	_
24	other	_	ADJ	_	Degree=Pos	_	_	_	_
25	pre-B	_	ADJ	_	Degree=Pos	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	specific	_	ADJ	_	Degree=Pos	_	_	_	_
29	genes	_	NOUN	_	Number=Plur	_	_	_	_
30	remain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	silent	_	ADJ	_	Degree=Pos	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Multiple	_	ADJ	_	Degree=Pos	_	_	_	_
2	functionally	_	ADV	_	_	_	_	_	_
3	important	_	ADJ	_	Degree=Pos	_	_	_	_
4	EBF	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	E47	_	NUM	_	Number=Sing	_	_	_	_
7	binding	_	NOUN	_	Number=Sing	_	_	_	_
8	sites	_	NOUN	_	Number=Plur	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	lambda5	_	NOUN	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
17	region	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
20	that	_	SCONJ	_	_	_	_	_	_
21	lambda5	_	NOUN	_	Number=Sing	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	direct	_	ADJ	_	Degree=Pos	_	_	_	_
25	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
26	target	_	NOUN	_	Number=Sing	_	_	_	_
27	for	_	ADP	_	_	_	_	_	_
28	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factors	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	EBF	_	PROPN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	E47	_	PROPN	_	Number=Sing	_	_	_	_
11	synergize	_	VERB	_	Number=Sing	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	subset	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	genes	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	define	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	early	_	ADJ	_	Degree=Pos	_	_	_	_
24	stage	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	lineage	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012996	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Characterization	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	platelet	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
10	molecule	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	promoter	_	NOUN	_	Number=Sing	_	_	_	_
14	:	_	PUNCT	_	_	_	_	_	_
15	identification	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	GATA	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	binding	_	NOUN	_	Number=Sing	_	_	_	_
22	element	_	NOUN	_	Number=Sing	_	_	_	_
23	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
26	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
27	activity	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Platelet	_	NOUN	_	Number=Sing	_	_	_	_
2	/	_	PUNCT	_	_	_	_	_	_
3	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
6	molecule	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	PECAM	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	130	_	NUM	_	NumType=Card	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kD	_	NOUN	_	Number=Sing	_	_	_	_
19	member	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	Ig	_	PROPN	_	Number=Sing	_	_	_	_
23	gene	_	NOUN	_	Number=Sing	_	_	_	_
24	superfamily	_	NOUN	_	Number=Sing	_	_	_	_
25	that	_	PRON	_	PronType=Rel	_	_	_	_
26	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
27	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	on	_	ADP	_	_	_	_	_	_
29	platelets	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	certain	_	ADJ	_	Degree=Pos	_	_	_	_
36	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
37	subsets	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
6	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	PECAM	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	cloned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	5	_	NUM	_	NumType=Card	_	_	_	_
19	'-	_	PUNCT	_	_	_	_	_	_
20	flanking	_	VERB	_	Number=Sing	_	_	_	_
21	region	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	PECAM	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	gene	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
31	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
32	activity	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	5	_	NUM	_	NumType=Card	_	_	_	_
2	'-	_	PUNCT	_	_	_	_	_	_
3	Rapid	_	ADJ	_	Degree=Pos	_	_	_	_
4	amplification	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	cDNA	_	PROPN	_	Number=Sing	_	_	_	_
7	ends	_	NOUN	_	Number=Plur	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	5'-	_	PUNCT	_	_	_	_	_	_
10	RACE	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	analysis	_	NOUN	_	Number=Sing	_	_	_	_
13	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	initiation	_	NOUN	_	Number=Sing	_	_	_	_
17	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	several	_	ADJ	_	Degree=Pos	_	_	_	_
20	closely	_	ADV	_	_	_	_	_	_
21	spaced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	nearby	_	ADV	_	_	_	_	_	_
23	sites	_	NOUN	_	Number=Plur	_	_	_	_
24	originating	_	VERB	_	VerbForm=Ger	_	_	_	_
25	approximately	_	ADV	_	_	_	_	_	_
26	204	_	NUM	_	NumType=Card	_	_	_	_
27	bp	_	NOUN	_	Number=Sing	_	_	_	_
28	upstream	_	NOUN	_	Number=Sing	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	translation	_	NOUN	_	Number=Sing	_	_	_	_
32	start	_	NOUN	_	Number=Sing	_	_	_	_
33	site	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	sequence	_	NOUN	_	Number=Sing	_	_	_	_
5	immediately	_	ADV	_	_	_	_	_	_
6	upstream	_	VERB	_	_	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	transcription	_	NOUN	_	Number=Sing	_	_	_	_
10	initiation	_	NOUN	_	Number=Sing	_	_	_	_
11	site	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	TIS	_	PROPN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	no	_	DET	_	_	_	_	_	_
17	canonical	_	ADJ	_	Degree=Pos	_	_	_	_
18	TATA	_	PROPN	_	Number=Sing	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	CAAT	_	NOUN	_	Number=Sing	_	_	_	_
21	elements	_	NOUN	_	Number=Plur	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	however	_	ADV	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	initiator	_	NOUN	_	Number=Sing	_	_	_	_
26	element	_	NOUN	_	Number=Sing	_	_	_	_
27	commonly	_	ADV	_	_	_	_	_	_
28	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	TATA	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	less	_	ADJ	_	Degree=Cmp	_	_	_	_
33	promoters	_	NOUN	_	Number=Plur	_	_	_	_
34	encompassed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	TIS	_	PROPN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	5	_	NUM	_	NumType=Card	_	_	_	_
2	'-	_	PUNCT	_	_	_	_	_	_
3	serially	_	ADV	_	_	_	_	_	_
4	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	PECAM	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	segments	_	NOUN	_	Number=Plur	_	_	_	_
10	cloned	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	front	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	luciferase	_	NOUN	_	Number=Sing	_	_	_	_
16	reporter	_	NOUN	_	Number=Sing	_	_	_	_
17	drove	_	VERB	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	both	_	CCONJ	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	lineage	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	orientation	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	specific	_	ADJ	_	Degree=Pos	_	_	_	_
28	manner	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Putative	_	ADJ	_	Degree=Pos	_	_	_	_
2	cis	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	acting	_	VERB	_	Number=Sing	_	_	_	_
5	control	_	NOUN	_	Number=Sing	_	_	_	_
6	elements	_	NOUN	_	Number=Plur	_	_	_	_
7	present	_	VERB	_	Degree=Pos	_	_	_	_
8	within	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	300	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	bp	_	NOUN	_	Number=Sing	_	_	_	_
13	core	_	NOUN	_	Number=Sing	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	included	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
16	two	_	NUM	_	NumType=Card	_	_	_	_
17	ets	_	NOUN	_	Number=Plur	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	tandem	_	NOUN	_	Number=Sing	_	_	_	_
25	E	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	box	_	NOUN	_	Number=Sing	_	_	_	_
28	domains	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	two	_	NUM	_	NumType=Card	_	_	_	_
31	GATA	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	sites	_	NOUN	_	Number=Plur	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	CACCC	_	PROPN	_	Number=Sing	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	AP	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	2	_	NUM	_	NumType=Card	_	_	_	_
43	binding	_	NOUN	_	Number=Sing	_	_	_	_
44	site	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	and	_	CCONJ	_	_	_	_	_	_
47	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
48	GATA	_	NOUN	_	Number=Sing	_	_	_	_
49	element	_	NOUN	_	Number=Sing	_	_	_	_
50	at	_	ADP	_	_	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	24	_	NUM	_	NumType=Card	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Mutational	_	ADJ	_	Degree=Pos	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	optimal	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	required	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	GATA	_	PROPN	_	Number=Sing	_	_	_	_
11	sequence	_	NOUN	_	Number=Sing	_	_	_	_
12	at	_	ADP	_	_	_	_	_	_
13	position	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	24	_	NUM	_	NumType=Card	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	gel	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	shift	_	NOUN	_	Number=Sing	_	_	_	_
21	assays	_	NOUN	_	Number=Plur	_	_	_	_
22	further	_	ADV	_	_	_	_	_	_
23	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	that	_	SCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	GATA	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factor	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	but	_	CCONJ	_	_	_	_	_	_
33	not	_	ADV	_	_	_	_	_	_
34	GATA	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	bound	_	ADJ	_	Degree=Pos	_	_	_	_
39	to	_	ADP	_	_	_	_	_	_
40	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
41	region	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	PECAM	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	promoter	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Understanding	_	VERB	_	VerbForm=Ger	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	cis	_	NOUN	_	Number=Plur	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	transacting	_	NOUN	_	Number=Sing	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	tissue	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	PECAM	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	should	_	AUX	_	VerbForm=Fin	_	_	_	_
20	increase	_	VERB	_	VerbForm=Inf	_	_	_	_
21	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
22	understanding	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	which	_	PRON	_	PronType=Int	_	_	_	_
28	vascular	_	ADJ	_	Degree=Pos	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	specific	_	ADJ	_	Degree=Pos	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	achieved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012998	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Ectopic	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	conditional	_	ADJ	_	Degree=Pos	_	_	_	_
6	GATA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2/estrogen	_	ADJ	_	NumType=Card	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	chimera	_	NOUN	_	Number=Sing	_	_	_	_
11	arrests	_	NOUN	_	Number=Plur	_	_	_	_
12	erythroid	_	VERB	_	Degree=Pos	_	_	_	_
13	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	hormone	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	manner	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GATA	_	NOUN	_	Number=Sing	_	_	_	_
3	factors	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	family	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
9	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
10	proteins	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	eukaryotes	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	share	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	extensive	_	ADJ	_	Degree=Pos	_	_	_	_
16	homology	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	DNA	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	binding	_	VERB	_	Number=Sing	_	_	_	_
22	domains	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	One	_	NUM	_	NumType=Card	_	_	_	_
2	enigmatic	_	ADJ	_	Degree=Pos	_	_	_	_
3	aspect	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	GATA	_	NOUN	_	Number=Sing	_	_	_	_
6	factor	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	several	_	ADJ	_	Degree=Pos	_	_	_	_
11	GATA	_	NOUN	_	Number=Sing	_	_	_	_
12	proteins	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	ostensibly	_	ADV	_	_	_	_	_	_
16	share	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	same	_	ADJ	_	Degree=Pos	_	_	_	_
19	DNA	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	binding	_	VERB	_	Number=Sing	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	specificity	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	coexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	elucidate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	roles	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	individual	_	ADJ	_	Degree=Pos	_	_	_	_
7	GATA	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	erythropoiesis	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	conditional	_	ADJ	_	Degree=Pos	_	_	_	_
13	alleles	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	GATA	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	GATA	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	GATA	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	3	_	NUM	_	NumType=Card	_	_	_	_
27	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	prepared	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	SCONJ	_	_	_	_	_	_
30	fusing	_	VERB	_	VerbForm=Ger	_	_	_	_
31	each	_	DET	_	_	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	factors	_	NOUN	_	Number=Plur	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	hormone	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	binding	_	VERB	_	Number=Sing	_	_	_	_
40	domain	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
43	human	_	ADJ	_	Degree=Pos	_	_	_	_
44	estrogen	_	NOUN	_	Number=Sing	_	_	_	_
45	receptor	_	NOUN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	ER	_	NOUN	_	Number=Sing	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	GATA	_	NOUN	_	Number=Sing	_	_	_	_
3	/	_	PUNCT	_	_	_	_	_	_
4	ER	_	NOUN	_	Number=Sing	_	_	_	_
5	chimeric	_	ADJ	_	Degree=Pos	_	_	_	_
6	factors	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	hormone	_	ADJ	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
14	trans	_	NOUN	_	Number=Plur	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	activating	_	VERB	_	VerbForm=Ger	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	transient	_	ADJ	_	Degree=Pos	_	_	_	_
20	transfection	_	NOUN	_	Number=Sing	_	_	_	_
21	assays	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	stably	_	ADV	_	_	_	_	_	_
3	introduced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	into	_	ADP	_	_	_	_	_	_
5	primary	_	ADJ	_	Degree=Pos	_	_	_	_
6	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	conditionally	_	ADV	_	_	_	_	_	_
9	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
11	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
15	GATA	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	2/ER	_	NOUN	_	Number=Sing	_	_	_	_
18	promoted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	terminal	_	ADJ	_	Number=Sing	_	_	_	_
23	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	estrogen	_	NOUN	_	Degree=Pos	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
29	manner	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	phenotypic	_	ADJ	_	Degree=Pos	_	_	_	_
3	effects	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	specifically	_	ADV	_	_	_	_	_	_
6	attributable	_	ADJ	_	Degree=Pos	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	action	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	ectopically	_	ADV	_	_	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	GATA	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2/ER	_	NOUN	_	Number=Sing	_	_	_	_
16	because	_	SCONJ	_	_	_	_	_	_
17	erythroblasts	_	NOUN	_	Number=Plur	_	_	_	_
18	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
19	exogenous	_	ADJ	_	Degree=Pos	_	_	_	_
20	GATA	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	constitutively	_	ADV	_	_	_	_	_	_
25	arrested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	because	_	SCONJ	_	_	_	_	_	_
30	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
31	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
32	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
33	either	_	CCONJ	_	_	_	_	_	_
34	Gal	_	NOUN	_	Number=Sing	_	_	_	_
35	/	_	PUNCT	_	_	_	_	_	_
36	ER	_	NOUN	_	Number=Sing	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	GATA	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	3/ER	_	NOUN	_	Number=Sing	_	_	_	_
41	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
42	not	_	PART	_	_	_	_	_	_
43	display	_	VERB	_	VerbForm=Inf	_	_	_	_
44	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
45	hormone	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
48	block	_	NOUN	_	Number=Sing	_	_	_	_
49	in	_	ADP	_	_	_	_	_	_
50	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	GATA	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	play	_	VERB	_	VerbForm=Inf	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	SCONJ	_	_	_	_	_	_
15	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	self	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	renewal	_	NOUN	_	Number=Sing	_	_	_	_
20	capacity	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	early	_	ADJ	_	Degree=Pos	_	_	_	_
23	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
24	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030012999	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Phorbol	_	PROPN	_	Number=Sing	_	_	_	_
2	ester	_	NOUN	_	Number=Sing	_	_	_	_
3	reduces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	mature	_	ADJ	_	Degree=Pos	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	potent	_	ADJ	_	Degree=Pos	_	_	_	_
5	mediator	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
16	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	play	_	VERB	_	VerbForm=Inf	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	role	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	genome	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
31	leukemias	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	little	_	ADJ	_	Degree=Pos	_	_	_	_
4	information	_	NOUN	_	Number=Sing	_	_	_	_
5	available	_	ADJ	_	Degree=Pos	_	_	_	_
6	on	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	response	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	normal	_	ADJ	_	Degree=Pos	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	32	_	NUM	_	NumType=Card	_	_	_	_
6	P-labeled	_	ADJ	_	Number=Sing	_	_	_	_
7	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
8	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
12	virus	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	HIV	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	_	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	long	_	ADJ	_	Degree=Pos	_	_	_	_
19	terminal	_	NOUN	_	Number=Sing	_	_	_	_
20	repeat	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	which	_	PRON	_	PronType=Rel	_	_	_	_
23	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	tandem	_	NOUN	_	Number=Sing	_	_	_	_
26	repeat	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	NF	_	PROPN	_	Number=Sing	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	binding	_	NOUN	_	Number=Sing	_	_	_	_
33	sequence	_	NOUN	_	Number=Sing	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	as	_	ADP	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	probe	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	gel	_	NOUN	_	Number=Sing	_	_	_	_
41	retardation	_	NOUN	_	Number=Sing	_	_	_	_
42	assay	_	NOUN	_	Number=Sing	_	_	_	_
43	to	_	PART	_	_	_	_	_	_
44	study	_	VERB	_	VerbForm=Inf	_	_	_	_
45	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
46	transcription	_	NOUN	_	Number=Sing	_	_	_	_
47	factor	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	assay	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	detected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	NF	_	PROPN	_	Number=Sing	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	extracts	_	NOUN	_	Number=Plur	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	normal	_	ADJ	_	Degree=Pos	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	normal	_	ADJ	_	Degree=Pos	_	_	_	_
4	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	12-0	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	tetradecanoyl	_	NOUN	_	Number=Sing	_	_	_	_
9	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	13	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	acetate	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	TPA	_	NOUN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	4	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	SYM	_	_	_	_	_	_
20	24	_	NUM	_	NumType=Card	_	_	_	_
21	h	_	NOUN	_	Number=Plur	_	_	_	_
22	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	complete	_	ADJ	_	Degree=Pos	_	_	_	_
25	disappearance	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	from	_	ADP	_	_	_	_	_	_
31	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
32	extracts	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	similar	_	ADJ	_	Degree=Pos	_	_	_	_
3	result	_	NOUN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	obtained	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	mature	_	ADJ	_	Degree=Pos	_	_	_	_
9	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	line	_	NOUN	_	Number=Sing	_	_	_	_
13	THP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	SP1	_	PROPN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	unaffected	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	addition	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	TPA	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	disappearance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
10	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
11	concentration	_	NOUN	_	Number=Sing	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	between	_	ADP	_	_	_	_	_	_
14	10	_	NUM	_	NumType=Card	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	50	_	NUM	_	NumType=Card	_	_	_	_
17	ng	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	ml	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
22	ester	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	THP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	TPA	_	PROPN	_	Number=Sing	_	_	_	_
8	also	_	ADV	_	_	_	_	_	_
9	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	new	_	ADJ	_	Degree=Pos	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	faster	_	ADJ	_	Degree=Cmp	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	migrating	_	VERB	_	VerbForm=Ger	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	species	_	NOUN	_	Number=Plur	_	_	_	_
20	not	_	ADV	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Protein	_	NOUN	_	Number=Sing	_	_	_	_
2	kinase	_	NOUN	_	Number=Sing	_	_	_	_
3	C	_	PROPN	_	Number=Sing	_	_	_	_
4	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
5	staurosporine	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	but	_	CCONJ	_	_	_	_	_	_
8	not	_	ADV	_	_	_	_	_	_
9	cyclic	_	ADJ	_	Degree=Pos	_	_	_	_
10	nucleotide	_	ADV	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	kinase	_	NOUN	_	Number=Sing	_	_	_	_
15	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
16	HA	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1004	_	NUM	_	NumType=Card	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	also	_	ADV	_	_	_	_	_	_
21	dramatically	_	ADV	_	_	_	_	_	_
22	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
24	levels	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B.	_	PROPN	_	Number=Sing	_	_	_	_
30	Finally	_	ADV	_	_	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	TPA	_	PROPN	_	Number=Sing	_	_	_	_
33	addition	_	NOUN	_	Number=Sing	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	monocytes	_	NOUN	_	Number=Sing	_	_	_	_
36	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	HIV	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	HIV	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	1	_	NUM	_	NumType=Card	_	_	_	_
45	replication	_	NOUN	_	Number=Sing	_	_	_	_
46	,	_	PUNCT	_	_	_	_	_	_
47	as	_	SCONJ	_	_	_	_	_	_
48	determined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
49	by	_	ADP	_	_	_	_	_	_
50	reverse	_	NOUN	_	Number=Sing	_	_	_	_
51	transcriptase	_	NOUN	_	Number=Sing	_	_	_	_
52	assays	_	NOUN	_	Number=Plur	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	in	_	ADP	_	_	_	_	_	_
55	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
56	concentration	_	NOUN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
59	manner	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	striking	_	ADJ	_	Degree=Pos	_	_	_	_
6	contrast	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	increase	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	HIV	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	replication	_	NOUN	_	Number=Sing	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
23	esters	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
26	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	U937	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	HL	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	60	_	NUM	_	NumType=Card	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	emphasize	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	importance	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	SCONJ	_	_	_	_	_	_
39	studying	_	VERB	_	VerbForm=Ger	_	_	_	_
40	cytokine	_	VERB	_	Degree=Pos	_	_	_	_
41	regulation	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	HIV	_	NOUN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	in	_	ADP	_	_	_	_	_	_
47	normal	_	ADJ	_	Degree=Pos	_	_	_	_
48	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013016	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Reactive	_	ADJ	_	Degree=Pos	_	_	_	_
2	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
3	intermediate	_	ADJ	_	Degree=Pos	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
6	NF	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	interleukin	_	ADJ	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1beta	_	PROPN	_	Number=Sing	_	_	_	_
14	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	5	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	lipoxygenase	_	NOUN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	NADPH	_	NOUN	_	Number=Sing	_	_	_	_
20	oxidase	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	role	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
9	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
10	intermediates	_	NOUN	_	Number=Plur	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	ROIs	_	NOUN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
21	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	cell	_	VERB	_	Number=Sing	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	sources	_	NOUN	_	Number=Plur	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	ROIs	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	various	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	types	_	NOUN	_	Number=Plur	_	_	_	_
11	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	yet	_	ADV	_	_	_	_	_	_
13	to	_	PART	_	_	_	_	_	_
14	be	_	AUX	_	VerbForm=Inf	_	_	_	_
15	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	might	_	AUX	_	VerbForm=Fin	_	_	_	_
18	include	_	VERB	_	VerbForm=Inf	_	_	_	_
19	5	_	NUM	_	NumType=Card	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	lipoxygenase	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	5	_	NUM	_	NumType=Card	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	LOX	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	NADPH	_	NOUN	_	Number=Sing	_	_	_	_
29	oxidase	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	5	_	NUM	_	NumType=Card	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	LOX	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	5	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	LOX	_	NOUN	_	Number=Sing	_	_	_	_
8	activating	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	FLAP	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	coexpressed	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	but	_	CCONJ	_	_	_	_	_	_
19	not	_	ADV	_	_	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	monocytic	_	ADJ	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1beta	_	PROPN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1beta	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	ROI	_	PROPN	_	Number=Sing	_	_	_	_
17	production	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	could	_	AUX	_	VerbForm=Fin	_	_	_	_
26	both	_	ADV	_	_	_	_	_	_
27	be	_	AUX	_	VerbForm=Inf	_	_	_	_
28	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	FLAP	_	NOUN	_	Number=Sing	_	_	_	_
33	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	confirming	_	VERB	_	VerbForm=Ger	_	_	_	_
36	that	_	SCONJ	_	_	_	_	_	_
37	5	_	NUM	_	NumType=Card	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	LOX	_	NOUN	_	Number=Sing	_	_	_	_
40	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	source	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	ROIs	_	NOUN	_	Number=Sing	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
47	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	for	_	ADP	_	_	_	_	_	_
49	NF	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
52	activation	_	NOUN	_	Number=Sing	_	_	_	_
53	in	_	ADP	_	_	_	_	_	_
54	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
55	cells	_	NOUN	_	Number=Plur	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	IL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1beta	_	PROPN	_	Number=Sing	_	_	_	_
4	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	not	_	PART	_	_	_	_	_	_
10	generate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	any	_	DET	_	_	_	_	_	_
12	ROIs	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	induction	_	NOUN	_	Number=Sing	_	_	_	_
18	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	influenced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	5	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	LOX	_	NOUN	_	Number=Sing	_	_	_	_
25	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	reintroduction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	functional	_	ADJ	_	Degree=Pos	_	_	_	_
7	5	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	LOX	_	NOUN	_	Number=Sing	_	_	_	_
10	system	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	allowed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	ROI	_	NOUN	_	Number=Sing	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	5	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	LOX	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	NF	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1beta	_	PROPN	_	Number=Sing	_	_	_	_
8	treatment	_	NOUN	_	Number=Sing	_	_	_	_
9	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	ROIs	_	NOUN	_	Number=Sing	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	independent	_	ADJ	_	Degree=Pos	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	5	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	LOX	_	NOUN	_	Number=Sing	_	_	_	_
23	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	NADPH	_	NOUN	_	Number=Sing	_	_	_	_
28	oxidase	_	NOUN	_	Number=Sing	_	_	_	_
29	activity	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	pathway	_	NOUN	_	Number=Sing	_	_	_	_
3	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	Rac1	_	PROPN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	Cdc42	_	PROPN	_	Number=Sing	_	_	_	_
8	GTPases	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	enzymes	_	NOUN	_	Number=Plur	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1beta	_	PROPN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	conclusion	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	three	_	NUM	_	NumType=Card	_	_	_	_
5	different	_	ADJ	_	Degree=Pos	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	specific	_	ADJ	_	Degree=Pos	_	_	_	_
9	pathways	_	NOUN	_	Number=Plur	_	_	_	_
10	lead	_	VERB	_	VerbForm=Inf	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1beta	_	PROPN	_	Number=Sing	_	_	_	_
20	:	_	PUNCT	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	pathway	_	NOUN	_	Number=Sing	_	_	_	_
23	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	ROI	_	NOUN	_	Number=Sing	_	_	_	_
26	production	_	NOUN	_	Number=Sing	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	5	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	LOX	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	lymphoid	_	ADJ	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	ROI	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	5	_	NUM	_	NumType=Card	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	LOX	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	independent	_	ADJ	_	Degree=Pos	_	_	_	_
44	pathway	_	NOUN	_	Number=Sing	_	_	_	_
45	in	_	ADP	_	_	_	_	_	_
46	epithelial	_	ADJ	_	Degree=Pos	_	_	_	_
47	cells	_	NOUN	_	Number=Plur	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
51	pathway	_	NOUN	_	Number=Sing	_	_	_	_
52	requiring	_	VERB	_	VerbForm=Ger	_	_	_	_
53	ROI	_	NOUN	_	Number=Sing	_	_	_	_
54	production	_	NOUN	_	Number=Sing	_	_	_	_
55	by	_	ADP	_	_	_	_	_	_
56	NADPH	_	NOUN	_	Number=Sing	_	_	_	_
57	oxidase	_	NOUN	_	Number=Sing	_	_	_	_
58	in	_	ADP	_	_	_	_	_	_
59	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
60	cells	_	NOUN	_	Number=Plur	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013021	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	GATA	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	basophils	_	NOUN	_	Number=Plur	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	potential	_	ADJ	_	Degree=Pos	_	_	_	_
17	role	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	hematopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factors	_	NOUN	_	Number=Plur	_	_	_	_
8	GATA	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	GATA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	GATA	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	3	_	NUM	_	NumType=Card	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	studied	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	basophils	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Eosinophils	_	PROPN	_	Number=Sing	_	_	_	_
2	express	_	VERB	_	Degree=Pos	_	_	_	_
3	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
4	for	_	ADP	_	_	_	_	_	_
5	GATA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	GATA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	GATA	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	3	_	NUM	_	NumType=Card	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Basophils	_	PROPN	_	Number=Plur	_	_	_	_
2	express	_	VERB	_	Number=Sing	_	_	_	_
3	GATA	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	GATA	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	3	_	NUM	_	NumType=Card	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	60	_	NUM	_	NumType=Card	_	_	_	_
6	eosinophilic	_	ADJ	_	Degree=Pos	_	_	_	_
7	sublines	_	NOUN	_	Number=Plur	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	either	_	CCONJ	_	_	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	5	_	NUM	_	NumType=Card	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	butyric	_	NOUN	_	Degree=Pos	_	_	_	_
15	acid	_	NOUN	_	Number=Sing	_	_	_	_
16	increased	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	GATA	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
24	concomitant	_	NOUN	_	Number=Sing	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	expression	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	eosinophil	_	ADJ	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	specific	_	ADJ	_	Degree=Pos	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	whereas	_	SCONJ	_	_	_	_	_	_
35	levels	_	NOUN	_	Number=Plur	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	GATA	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
41	remained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
42	relatively	_	ADV	_	_	_	_	_	_
43	constant	_	ADJ	_	Degree=Pos	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	presence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	basophils	_	NOUN	_	Number=Plur	_	_	_	_
12	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	that	_	SCONJ	_	_	_	_	_	_
14	gene	_	NOUN	_	Number=Sing	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
18	lineages	_	NOUN	_	Number=Plur	_	_	_	_
19	may	_	AUX	_	VerbForm=Fin	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	GATA	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	binding	_	VERB	_	Number=Sing	_	_	_	_
26	proteins	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013026	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
3	binding	_	VERB	_	Number=Sing	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
6	enhances	_	VERB	_	Number=Plur	_	_	_	_
7	IFN	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	gamma	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	early	_	ADJ	_	Degree=Pos	_	_	_	_
13	signaling	_	NOUN	_	Number=Sing	_	_	_	_
14	events	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
2	integrins	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	fundamentally	_	ADV	_	_	_	_	_	_
5	important	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	SCONJ	_	_	_	_	_	_
7	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	matrix	_	NOUN	_	Number=Sing	_	_	_	_
12	components	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	other	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	integrin	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
5	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
6	controls	_	NOUN	_	Number=Sing	_	_	_	_
7	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
8	arrest	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	extravasation	_	NOUN	_	Number=Sing	_	_	_	_
11	during	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	onset	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	responses	_	NOUN	_	Number=Plur	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	integrin	_	ADJ	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	ligand	_	NOUN	_	Degree=Pos	_	_	_	_
6	interactions	_	NOUN	_	Number=Plur	_	_	_	_
7	trigger	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	signaling	_	VERB	_	VerbForm=Ger	_	_	_	_
9	pathways	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	may	_	AUX	_	VerbForm=Fin	_	_	_	_
12	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
13	leukocyte	_	ADJ	_	Degree=Pos	_	_	_	_
14	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	function	_	NOUN	_	Number=Sing	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	sites	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	current	_	ADJ	_	Degree=Pos	_	_	_	_
4	studies	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	evaluated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	combinatorial	_	ADJ	_	Degree=Pos	_	_	_	_
10	effects	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
13	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	IFN	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	gamma	_	NOUN	_	Number=Sing	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
20	signaling	_	NOUN	_	Number=Sing	_	_	_	_
21	pathways	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	IFN	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	gamma	_	NOUN	_	Number=Sing	_	_	_	_
4	triggers	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	well	_	ADV	_	Degree=Pos	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	defined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	signal	_	NOUN	_	Number=Sing	_	_	_	_
10	transduction	_	NOUN	_	Number=Sing	_	_	_	_
11	pathway	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	although	_	SCONJ	_	_	_	_	_	_
15	not	_	PART	_	_	_	_	_	_
16	directly	_	ADV	_	_	_	_	_	_
17	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
20	adherence	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	arginine	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	glycine	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	aspartate	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	RGD	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	coated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	substrata	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
37	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	significantly	_	ADV	_	_	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
41	matrix	_	NOUN	_	Degree=Pos	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	adherent	_	ADJ	_	Degree=Pos	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	suspension	_	NOUN	_	Number=Sing	_	_	_	_
6	or	_	CCONJ	_	_	_	_	_	_
7	adherent	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	plastic	_	ADJ	_	Degree=Pos	_	_	_	_
10	surfaces	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
13	adherent	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	fibronectin	_	NOUN	_	Number=Sing	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	RGD	_	PROPN	_	Number=Sing	_	_	_	_
18	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
21	than	_	ADP	_	_	_	_	_	_
22	threefold	_	ADJ	_	Degree=Pos	_	_	_	_
23	increase	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	steady	_	ADJ	_	Degree=Pos	_	_	_	_
26	state	_	NOUN	_	Number=Sing	_	_	_	_
27	levels	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	IFN	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	gamma	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
35	for	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	high	_	ADJ	_	Degree=Pos	_	_	_	_
38	affinity	_	NOUN	_	Number=Sing	_	_	_	_
39	Fc	_	PROPN	_	Number=Sing	_	_	_	_
40	gammaRI	_	NOUN	_	Number=Sing	_	_	_	_
41	receptor	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	increase	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	5	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	10	_	NUM	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	fold	_	NOUN	_	Number=Sing	_	_	_	_
21	increase	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	STAT1	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
27	DNA	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	binding	_	VERB	_	Number=Sing	_	_	_	_
30	complex	_	NOUN	_	Number=Sing	_	_	_	_
31	that	_	PRON	_	PronType=Rel	_	_	_	_
32	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	Fc	_	PROPN	_	Number=Sing	_	_	_	_
35	gammaRI	_	NOUN	_	Number=Sing	_	_	_	_
36	promoter	_	NOUN	_	Number=Sing	_	_	_	_
37	elements	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
5	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	STAT1	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
11	kinases	_	NOUN	_	Number=Plur	_	_	_	_
12	JAK1	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	JAK2	_	PROPN	_	Number=Sing	_	_	_	_
15	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
16	enhanced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	significantly	_	ADV	_	_	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	RGD	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	adherent	_	ADJ	_	Degree=Pos	_	_	_	_
22	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	control	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	novel	_	NOUN	_	Number=Sing	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	which	_	PRON	_	PronType=Rel	_	_	_	_
9	integrin	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	modulate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	signal	_	NOUN	_	Number=Sing	_	_	_	_
23	transduction	_	NOUN	_	Number=Sing	_	_	_	_
24	pathways	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	thereby	_	ADV	_	_	_	_	_	_
27	amplifying	_	VERB	_	VerbForm=Ger	_	_	_	_
28	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
29	events	_	NOUN	_	Number=Plur	_	_	_	_
30	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	monocyte	_	NOUN	_	Number=Sing	_	_	_	_
33	activation	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013028	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Repression	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	Ikaros	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Aiolos	_	PROPN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	through	_	ADP	_	_	_	_	_	_
9	histone	_	ADJ	_	Number=Sing	_	_	_	_
10	deacetylase	_	NOUN	_	Number=Sing	_	_	_	_
11	complexes	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
7	lineage	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	determining	_	NOUN	_	VerbForm=Ger	_	_	_	_
10	factors	_	NOUN	_	Number=Plur	_	_	_	_
11	Ikaros	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	Aiolos	_	PROPN	_	Number=Sing	_	_	_	_
14	can	_	AUX	_	VerbForm=Fin	_	_	_	_
15	function	_	VERB	_	VerbForm=Inf	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	strong	_	ADJ	_	Degree=Pos	_	_	_	_
18	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
19	repressors	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	function	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	through	_	ADP	_	_	_	_	_	_
6	two	_	NUM	_	NumType=Card	_	_	_	_
7	repression	_	NOUN	_	Number=Sing	_	_	_	_
8	domains	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
12	upon	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	promoter	_	NOUN	_	Degree=Pos	_	_	_	_
15	context	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	cell	_	NOUN	_	Number=Sing	_	_	_	_
18	type	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Repression	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	Ikaros	_	PROPN	_	Number=Sing	_	_	_	_
4	proteins	_	NOUN	_	Number=Plur	_	_	_	_
5	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	hypo	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	acetylation	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	core	_	NOUN	_	Number=Sing	_	_	_	_
12	histones	_	NOUN	_	Number=Plur	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	promoter	_	NOUN	_	Number=Sing	_	_	_	_
15	sites	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	relieved	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	histone	_	NOUN	_	Number=Sing	_	_	_	_
21	deacetylase	_	NOUN	_	Number=Sing	_	_	_	_
22	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Consistent	_	ADJ	_	Degree=Pos	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	findings	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	Ikaros	_	PROPN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
9	repression	_	NOUN	_	Number=Sing	_	_	_	_
10	domains	_	NOUN	_	Number=Plur	_	_	_	_
11	can	_	AUX	_	VerbForm=Fin	_	_	_	_
12	interact	_	VERB	_	VerbForm=Inf	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vivo	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	vitro	_	NOUN	_	Number=Sing	_	_	_	_
18	with	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	mSin3	_	NOUN	_	Degree=Pos	_	_	_	_
21	family	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	co-repressors	_	NOUN	_	Number=Plur	_	_	_	_
24	which	_	PRON	_	PronType=Rel	_	_	_	_
25	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	to	_	ADP	_	_	_	_	_	_
27	histone	_	VERB	_	Number=Sing	_	_	_	_
28	deacetylases	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	on	_	ADP	_	_	_	_	_	_
3	these	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
6	recent	_	ADJ	_	Degree=Pos	_	_	_	_
7	findings	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	associations	_	NOUN	_	Number=Plur	_	_	_	_
10	between	_	ADP	_	_	_	_	_	_
11	Ikaros	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	Mi-2	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	HDAC	_	PROPN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
18	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	Ikaros	_	PROPN	_	Number=Sing	_	_	_	_
21	family	_	NOUN	_	Number=Sing	_	_	_	_
22	members	_	NOUN	_	Number=Plur	_	_	_	_
23	modulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	during	_	ADP	_	_	_	_	_	_
27	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
28	development	_	NOUN	_	Number=Sing	_	_	_	_
29	by	_	SCONJ	_	_	_	_	_	_
30	recruiting	_	NOUN	_	Number=Sing	_	_	_	_
31	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
32	histone	_	NOUN	_	Number=Sing	_	_	_	_
33	deacetylase	_	NOUN	_	Number=Sing	_	_	_	_
34	complexes	_	NOUN	_	Number=Plur	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	specific	_	ADJ	_	Degree=Pos	_	_	_	_
37	promoters	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013032	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
6	drug	_	NOUN	_	Number=Sing	_	_	_	_
7	resistance	_	NOUN	_	Number=Sing	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	SCONJ	_	_	_	_	_	_
13	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	Fas	_	NOUN	_	Number=Sing	_	_	_	_
26	ligand	_	NOUN	_	Number=Sing	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
5	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	variety	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	including	_	VERB	_	VerbForm=Ger	_	_	_	_
14	chemotherapy	_	NOUN	_	Number=Sing	_	_	_	_
15	drugs	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	generally	_	ADV	_	_	_	_	_	_
4	accepted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
11	antiapoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
12	effects	_	NOUN	_	Number=Plur	_	_	_	_
13	mainly	_	ADV	_	_	_	_	_	_
14	by	_	SCONJ	_	_	_	_	_	_
15	dimerizing	_	VERB	_	VerbForm=Ger	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	proapoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
18	members	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2	_	NUM	_	NumType=Card	_	_	_	_
24	family	_	NOUN	_	Number=Sing	_	_	_	_
25	such	_	ADJ	_	Degree=Pos	_	_	_	_
26	as	_	ADP	_	_	_	_	_	_
27	Bax	_	PROPN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	Bad	_	PROPN	_	Degree=Pos	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	antiapoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
8	effects	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Paclitaxel	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	other	_	ADJ	_	Degree=Pos	_	_	_	_
4	drugs	_	NOUN	_	Number=Plur	_	_	_	_
5	that	_	PRON	_	PronType=Rel	_	_	_	_
6	disturb	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	microtubule	_	NOUN	_	Degree=Pos	_	_	_	_
8	dynamics	_	NOUN	_	Number=Plur	_	_	_	_
9	kill	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	Fas	_	NOUN	_	Number=Sing	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	Fas	_	NOUN	_	Number=Sing	_	_	_	_
16	ligand	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	FasL	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	manner	_	NOUN	_	Number=Sing	_	_	_	_
23	;	_	PUNCT	_	_	_	_	_	_
24	antibody	_	NOUN	_	Number=Sing	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	FasL	_	VERB	_	Number=Sing	_	_	_	_
27	inhibits	_	NOUN	_	Number=Plur	_	_	_	_
28	paclitaxel	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	overexpression	_	NOUN	_	Number=Sing	_	_	_	_
9	leads	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	prevention	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	chemotherapy	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	paclitaxel	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	FasL	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	blocks	_	NOUN	_	Number=Plur	_	_	_	_
25	paclitaxel	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	prevents	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	translocation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	transcription	_	NOUN	_	Number=Sing	_	_	_	_
27	factor	_	NOUN	_	Number=Sing	_	_	_	_
28	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	microtubule	_	NOUN	_	Degree=Pos	_	_	_	_
31	damage	_	NOUN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	binding	_	VERB	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	sequestering	_	VERB	_	VerbForm=Ger	_	_	_	_
37	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	calcium	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
43	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
44	that	_	PRON	_	PronType=Rel	_	_	_	_
45	must	_	AUX	_	VerbForm=Fin	_	_	_	_
46	dephosphorylate	_	VERB	_	VerbForm=Inf	_	_	_	_
47	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
48	to	_	PART	_	_	_	_	_	_
49	move	_	VERB	_	VerbForm=Inf	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
52	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Without	_	ADP	_	_	_	_	_	_
2	NFAT	_	ADJ	_	Number=Sing	_	_	_	_
3	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
4	translocation	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	FasL	_	ADJ	_	Degree=Pos	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	transcribed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	paclitaxel	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	other	_	ADJ	_	Degree=Pos	_	_	_	_
9	drugs	_	NOUN	_	Number=Plur	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	disturb	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	microtubule	_	NOUN	_	Degree=Pos	_	_	_	_
13	function	_	NOUN	_	Number=Sing	_	_	_	_
14	kill	_	VERB	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	at	_	ADV	_	_	_	_	_	_
17	least	_	ADV	_	Degree=Sup	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	part	_	NOUN	_	Number=Sing	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	induction	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	FasL	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	antagonizes	_	VERB	_	Number=Plur	_	_	_	_
7	drug	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	SCONJ	_	_	_	_	_	_
12	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
14	activation	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	blocking	_	VERB	_	VerbForm=Ger	_	_	_	_
17	NFAT	_	ADJ	_	Number=Sing	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	translocation	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	FasL	_	ADJ	_	Degree=Pos	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	overcome	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	at	_	ADV	_	_	_	_	_	_
12	least	_	ADV	_	Degree=Sup	_	_	_	_
13	partially	_	ADV	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Phosphorylated	_	VERB	_	Number=Sing	_	_	_	_
2	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	2	_	NUM	_	NumType=Card	_	_	_	_
5	can	_	AUX	_	VerbForm=Fin	_	_	_	_
6	not	_	PART	_	_	_	_	_	_
7	bind	_	VERB	_	VerbForm=Inf	_	_	_	_
8	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	NFAT	_	NOUN	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	FasL	_	ADJ	_	Degree=Pos	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
19	can	_	AUX	_	VerbForm=Fin	_	_	_	_
20	occur	_	VERB	_	VerbForm=Inf	_	_	_	_
21	after	_	ADP	_	_	_	_	_	_
22	Bcl	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	2	_	NUM	_	NumType=Card	_	_	_	_
25	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013033	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	critical	_	ADJ	_	Degree=Pos	_	_	_	_
8	regulator	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
12	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vitro	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	During	_	ADP	_	_	_	_	_	_
2	beneficial	_	ADJ	_	Degree=Pos	_	_	_	_
3	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	potentially	_	ADV	_	_	_	_	_	_
6	tissue	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	damaging	_	ADJ	_	Degree=Pos	_	_	_	_
9	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
10	undergo	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
12	before	_	SCONJ	_	_	_	_	_	_
13	being	_	AUX	_	VerbForm=Ger	_	_	_	_
14	cleared	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	phagocytes	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	non-phlogistic	_	ADJ	_	Degree=Pos	_	_	_	_
20	manner	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	rate	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
9	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	eosinophils	_	NOUN	_	Number=Plur	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	greatly	_	ADV	_	_	_	_	_	_
17	accelerated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	both	_	CCONJ	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	concentration	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	manner	_	NOUN	_	Number=Sing	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	fungal	_	ADJ	_	Degree=Pos	_	_	_	_
30	metabolite	_	NOUN	_	Number=Sing	_	_	_	_
31	gliotoxin	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	but	_	CCONJ	_	_	_	_	_	_
34	not	_	ADV	_	_	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
37	inactive	_	ADJ	_	Degree=Pos	_	_	_	_
38	analog	_	NOUN	_	Number=Sing	_	_	_	_
39	methylthiogliotoxin	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	abolished	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	caspase	_	NOUN	_	Number=Sing	_	_	_	_
10	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
11	zVAD	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	fmk	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	correlated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	kappa	_	NOUN	_	Number=Sing	_	_	_	_
24	B	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
33	mimicked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	by	_	ADP	_	_	_	_	_	_
35	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	permeable	_	ADJ	_	Degree=Pos	_	_	_	_
38	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
39	peptide	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	NF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	SN	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	50	_	NUM	_	NumType=Card	_	_	_	_
48	;	_	PUNCT	_	_	_	_	_	_
49	other	_	ADJ	_	Degree=Pos	_	_	_	_
50	NF	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
53	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
54	,	_	PUNCT	_	_	_	_	_	_
55	curcumin	_	NOUN	_	Number=Sing	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	pyrrolidine	_	NOUN	_	Number=Sing	_	_	_	_
58	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
59	;	_	PUNCT	_	_	_	_	_	_
60	and	_	CCONJ	_	_	_	_	_	_
61	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
62	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
63	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
64	,	_	PUNCT	_	_	_	_	_	_
65	MG	_	NOUN	_	Number=Sing	_	_	_	_
66	-	_	PUNCT	_	_	_	_	_	_
67	132	_	NUM	_	NumType=Card	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	Gliotoxin	_	PROPN	_	Number=Sing	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	dramatically	_	ADV	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	early	_	ADJ	_	Degree=Pos	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	-	_	SYM	_	_	_	_	_	_
10	6	_	NUM	_	NumType=Card	_	_	_	_
11	h	_	NOUN	_	Number=Plur	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	pro-apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
14	effects	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	tumor	_	NOUN	_	Number=Sing	_	_	_	_
17	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
18	factor	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	alpha	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	TNF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	unmasked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	ability	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	TNF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	alpha	_	NOUN	_	Number=Sing	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
38	eosinophil	_	ADJ	_	Number=Sing	_	_	_	_
39	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	TNF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	alpha	_	PROPN	_	Number=Sing	_	_	_	_
7	caused	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	gliotoxin	_	ADJ	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	inhibitable	_	ADJ	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
16	form	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	response	_	NOUN	_	Number=Sing	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	may	_	AUX	_	VerbForm=Fin	_	_	_	_
26	underlie	_	VERB	_	VerbForm=Inf	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	ability	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	TNF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	alpha	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	PART	_	_	_	_	_	_
34	delay	_	VERB	_	VerbForm=Inf	_	_	_	_
35	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
36	at	_	ADP	_	_	_	_	_	_
37	later	_	ADJ	_	Degree=Cmp	_	_	_	_
38	times	_	NOUN	_	Number=Plur	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	12	_	NUM	_	NumType=Card	_	_	_	_
41	-	_	SYM	_	_	_	_	_	_
42	24	_	NUM	_	NumType=Card	_	_	_	_
43	h	_	NOUN	_	_	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	limit	_	VERB	_	VerbForm=Inf	_	_	_	_
47	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
48	early	_	ADJ	_	Degree=Pos	_	_	_	_
49	killing	_	VERB	_	VerbForm=Ger	_	_	_	_
50	effect	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cycloheximide	_	NOUN	_	Number=Sing	_	_	_	_
4	displayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	similar	_	ADJ	_	Degree=Pos	_	_	_	_
7	capacity	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	enhance	_	VERB	_	VerbForm=Inf	_	_	_	_
10	TNF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	alpha	_	PROPN	_	Number=Sing	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	neutrophil	_	NOUN	_	Number=Sing	_	_	_	_
15	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
16	even	_	ADV	_	_	_	_	_	_
17	at	_	ADP	_	_	_	_	_	_
18	time	_	NOUN	_	Number=Sing	_	_	_	_
19	points	_	NOUN	_	Number=Plur	_	_	_	_
20	when	_	ADV	_	PronType=Int	_	_	_	_
21	cycloheximide	_	PROPN	_	Number=Sing	_	_	_	_
22	alone	_	ADV	_	_	_	_	_	_
23	had	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
24	no	_	DET	_	_	_	_	_	_
25	pro-apoptotic	_	ADJ	_	Degree=Pos	_	_	_	_
26	effect	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
29	that	_	SCONJ	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
33	may	_	AUX	_	VerbForm=Fin	_	_	_	_
34	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	production	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	protein	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	s	_	X	_	_	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	which	_	PRON	_	PronType=Rel	_	_	_	_
43	protect	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
44	neutrophils	_	NOUN	_	Number=Plur	_	_	_	_
45	from	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
48	effects	_	NOUN	_	Number=Plur	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	TNF	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	alpha	_	NOUN	_	Number=Sing	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	shed	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	light	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
10	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
11	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
14	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	particular	_	ADJ	_	Degree=Pos	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	that	_	SCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
28	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
31	role	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	SCONJ	_	_	_	_	_	_
33	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	death	_	NOUN	_	Number=Sing	_	_	_	_
38	pathway	_	NOUN	_	Number=Sing	_	_	_	_
39	in	_	ADP	_	_	_	_	_	_
40	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013034	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Tissue	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	specific	_	ADJ	_	Degree=Pos	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	tuberous	_	ADJ	_	Degree=Pos	_	_	_	_
11	sclerosis	_	ADJ	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	TSC2	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	tissues	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	TSC2	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
7	16p13.3	_	NUM	_	NumType=Card	_	_	_	_
8	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	autosomal	_	ADJ	_	Degree=Pos	_	_	_	_
12	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
13	neurocutaneous	_	ADJ	_	Degree=Pos	_	_	_	_
14	disorder	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	tuberous	_	ADJ	_	Degree=Pos	_	_	_	_
17	sclerosis	_	NOUN	_	Number=Sing	_	_	_	_
18	complex	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	TSC	_	PROPN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	By	_	SCONJ	_	_	_	_	_	_
2	using	_	VERB	_	VerbForm=Ger	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	partial	_	ADJ	_	Degree=Pos	_	_	_	_
5	nucleotide	_	NOUN	_	Number=Sing	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	cloned	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
10	TSC2	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
13	chain	_	NOUN	_	Number=Sing	_	_	_	_
14	reaction	_	NOUN	_	Number=Sing	_	_	_	_
15	methodology	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
18	constructed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	digoxigenin	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	labeled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	complementary	_	ADJ	_	Degree=Pos	_	_	_	_
24	DNA	_	NOUN	_	Number=Sing	_	_	_	_
25	probe	_	NOUN	_	Number=Sing	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	examine	_	VERB	_	VerbForm=Inf	_	_	_	_
28	TSC2	_	PROPN	_	Number=Sing	_	_	_	_
29	gene	_	NOUN	_	Number=Sing	_	_	_	_
30	expression	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	autopsy	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	or	_	CCONJ	_	_	_	_	_	_
35	biopsy	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	human	_	ADJ	_	Degree=Pos	_	_	_	_
39	tissues	_	NOUN	_	Number=Plur	_	_	_	_
40	by	_	ADP	_	_	_	_	_	_
41	in	_	ADP	_	_	_	_	_	_
42	situ	_	NOUN	_	Number=Sing	_	_	_	_
43	hybridization	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	TSC2	_	PROPN	_	Number=Sing	_	_	_	_
2	messenger	_	NOUN	_	Number=Sing	_	_	_	_
3	RNA	_	PROPN	_	Number=Sing	_	_	_	_
4	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
5	widely	_	ADV	_	_	_	_	_	_
6	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	various	_	ADJ	_	Degree=Pos	_	_	_	_
9	cell	_	NOUN	_	Number=Sing	_	_	_	_
10	types	_	NOUN	_	Number=Plur	_	_	_	_
11	throughout	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	body	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	including	_	VERB	_	VerbForm=Ger	_	_	_	_
16	epithelia	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	endocrine	_	NOUN	_	Degree=Pos	_	_	_	_
24	functions	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	e.g.	_	X	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	adrenal	_	ADJ	_	Degree=Pos	_	_	_	_
29	cortex	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	anterior	_	ADJ	_	Degree=Pos	_	_	_	_
32	pituitary	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	prominently	_	ADV	_	_	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	selectively	_	ADV	_	_	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	within	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	central	_	ADJ	_	Degree=Pos	_	_	_	_
10	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
11	system	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	pyramidal	_	ADJ	_	Degree=Pos	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cerebral	_	ADJ	_	Degree=Pos	_	_	_	_
20	cortex	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	other	_	ADJ	_	Degree=Pos	_	_	_	_
23	motor	_	NOUN	_	Number=Sing	_	_	_	_
24	neurons	_	NOUN	_	Number=Plur	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	e.g.	_	X	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	spinal	_	ADJ	_	Degree=Pos	_	_	_	_
30	cord	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	brainstem	_	NOUN	_	Number=Sing	_	_	_	_
33	nuclei	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Visceral	_	PROPN	_	Number=Sing	_	_	_	_

1	TSC2	_	PROPN	_	Number=Sing	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	autopsy	_	NOUN	_	Number=Sing	_	_	_	_
7	tissues	_	NOUN	_	Number=Plur	_	_	_	_
8	from	_	ADP	_	_	_	_	_	_
9	patients	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	without	_	ADP	_	_	_	_	_	_
13	TSC	_	PROPN	_	Number=Sing	_	_	_	_
14	;	_	PUNCT	_	_	_	_	_	_
15	TSC2	_	PROPN	_	Number=Sing	_	_	_	_
16	messenger	_	NOUN	_	Number=Sing	_	_	_	_
17	RNA	_	PROPN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	most	_	ADV	_	_	_	_	_	_
21	prominent	_	ADJ	_	Degree=Pos	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	with	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
27	mitotic	_	ADJ	_	Degree=Pos	_	_	_	_
28	rate	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	turnover	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	e.g.	_	ADV	_	_	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	epithelia	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	central	_	ADJ	_	Degree=Pos	_	_	_	_
40	nervous	_	ADJ	_	Degree=Pos	_	_	_	_
41	system	_	NOUN	_	Number=Sing	_	_	_	_
42	pyramidal	_	ADJ	_	Degree=Pos	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	and	_	CCONJ	_	_	_	_	_	_
45	other	_	ADJ	_	Degree=Pos	_	_	_	_
46	neurons	_	NOUN	_	Number=Plur	_	_	_	_
47	being	_	AUX	_	VerbForm=Ger	_	_	_	_
48	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
49	obvious	_	ADJ	_	Degree=Pos	_	_	_	_
50	exception	_	NOUN	_	Number=Sing	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	and	_	CCONJ	_	_	_	_	_	_
53	/	_	PUNCT	_	_	_	_	_	_
54	or	_	CCONJ	_	_	_	_	_	_
55	in	_	ADP	_	_	_	_	_	_
56	cells	_	NOUN	_	Number=Plur	_	_	_	_
57	with	_	ADP	_	_	_	_	_	_
58	important	_	ADJ	_	Degree=Pos	_	_	_	_
59	secretory	_	NOUN	_	Number=Sing	_	_	_	_
60	/	_	PUNCT	_	_	_	_	_	_
61	transport	_	NOUN	_	Number=Sing	_	_	_	_
62	functions	_	NOUN	_	Number=Plur	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	widespread	_	ADJ	_	Degree=Pos	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	TSC2	_	PROPN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	supports	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	view	_	NOUN	_	Number=Sing	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
13	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	protein	_	NOUN	_	Number=Sing	_	_	_	_
16	vital	_	ADJ	_	Degree=Pos	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	cell	_	VERB	_	VerbForm=Inf	_	_	_	_
19	growth	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	metabolism	_	NOUN	_	Number=Sing	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	one	_	NUM	_	NumType=Card	_	_	_	_
24	that	_	DET	_	PronType=Rel	_	_	_	_
25	functions	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	as	_	ADP	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	tumor	_	NOUN	_	Number=Sing	_	_	_	_
29	/	_	PUNCT	_	_	_	_	_	_
30	growth	_	NOUN	_	Number=Sing	_	_	_	_
31	suppressor	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013035	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Retinoid	_	NOUN	_	Number=Sing	_	_	_	_
2	X	_	SYM	_	_	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	c-cerbA	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
8	hormone	_	NOUN	_	Number=Sing	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
11	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	growth	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	receptors	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	important	_	ADJ	_	Degree=Pos	_	_	_	_
5	regulators	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	development	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	impact	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	retinoid	_	NOUN	_	Number=Sing	_	_	_	_
8	X	_	PROPN	_	_	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	RXR	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
15	acid	_	NOUN	_	Number=Sing	_	_	_	_
16	receptor	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	RAR	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	thyroid	_	NOUN	_	Number=Sing	_	_	_	_
27	hormone	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	T3	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	receptor	_	NOUN	_	Number=Sing	_	_	_	_
32	(	_	PUNCT	_	_	_	_	_	_
33	c	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	erbA	_	NOUN	_	Number=Sing	_	_	_	_
36	/	_	PUNCT	_	_	_	_	_	_
37	TR	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	on	_	ADP	_	_	_	_	_	_
40	growth	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	using	_	VERB	_	VerbForm=Ger	_	_	_	_
47	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
48	in	_	ADP	_	_	_	_	_	_
49	vitro	_	ADJ	_	Degree=Pos	_	_	_	_
50	culture	_	NOUN	_	Number=Sing	_	_	_	_
51	system	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	stem	_	NOUN	_	Degree=Pos	_	_	_	_
54	cell	_	NOUN	_	Number=Sing	_	_	_	_
55	factor	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
58	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
59	progenitors	_	NOUN	_	Number=Plur	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	RXR	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	RAR	_	PROPN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
7	/	_	PUNCT	_	_	_	_	_	_
8	TR	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	ligands	_	NOUN	_	Number=Plur	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
16	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	specific	_	ADJ	_	Degree=Pos	_	_	_	_
19	gene	_	NOUN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	accelerate	_	VERB	_	VerbForm=Inf	_	_	_	_
24	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
25	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	culture	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	with	_	SCONJ	_	_	_	_	_	_
30	T3	_	NOUN	_	Number=Sing	_	_	_	_
31	being	_	AUX	_	VerbForm=Ger	_	_	_	_
32	most	_	ADV	_	_	_	_	_	_
33	effective	_	ADJ	_	Degree=Pos	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	while	_	SCONJ	_	_	_	_	_	_
4	ligand	_	ADJ	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	TR	_	NOUN	_	Number=Sing	_	_	_	_
10	accelerated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	unliganded	_	ADJ	_	Degree=Pos	_	_	_	_
14	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	TR	_	NOUN	_	Number=Sing	_	_	_	_
17	effectively	_	ADV	_	_	_	_	_	_
18	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	supported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
24	growth	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	culture	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	c-erbA/TR	_	NOUN	_	Number=Sing	_	_	_	_
4	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	act	_	VERB	_	VerbForm=Inf	_	_	_	_
7	as	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	binary	_	ADJ	_	Degree=Pos	_	_	_	_
10	switch	_	NOUN	_	Number=Sing	_	_	_	_
11	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
12	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	fate	_	NOUN	_	Number=Sing	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	unliganded	_	ADJ	_	Degree=Pos	_	_	_	_
17	c-erbA/TR	_	NOUN	_	Number=Sing	_	_	_	_
18	supports	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	growth	_	NOUN	_	Number=Sing	_	_	_	_
20	while	_	SCONJ	_	_	_	_	_	_
21	ligand	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	c-erbA	_	NOUN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	TR	_	NOUN	_	Number=Sing	_	_	_	_
27	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Additionally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	to	_	PART	_	_	_	_	_	_
4	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	impact	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	RXR	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	development	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
15	interfering	_	VERB	_	VerbForm=Ger	_	_	_	_
16	mutant	_	ADJ	_	Number=Sing	_	_	_	_
17	RXRs	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	activator	_	NOUN	_	Number=Sing	_	_	_	_
23	functions	_	NOUN	_	Number=Plur	_	_	_	_
24	AF	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	AF	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	AF	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	2	_	NUM	_	NumType=Card	_	_	_	_
36	only	_	ADV	_	_	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	or	_	CCONJ	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	entire	_	ADJ	_	Degree=Pos	_	_	_	_
41	DNA	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	binding	_	VERB	_	Number=Sing	_	_	_	_
44	domain	_	NOUN	_	Number=Sing	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
47	introduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
48	into	_	ADP	_	_	_	_	_	_
49	erythroid	_	ADJ	_	Degree=Pos	_	_	_	_
50	progenitor	_	NOUN	_	Number=Sing	_	_	_	_
51	cells	_	NOUN	_	Number=Plur	_	_	_	_
52	via	_	ADP	_	_	_	_	_	_
53	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
54	retrovirus	_	NOUN	_	Number=Sing	_	_	_	_
55	vectors	_	NOUN	_	Number=Plur	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	analyzed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
58	for	_	ADP	_	_	_	_	_	_
59	RXR	_	NOUN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	specific	_	ADJ	_	Degree=Pos	_	_	_	_
62	effects	_	NOUN	_	Number=Plur	_	_	_	_
63	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	wild	_	ADJ	_	Degree=Pos	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	RXR	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	RXR	_	PROPN	_	Number=Sing	_	_	_	_
15	mutants	_	NOUN	_	Number=Plur	_	_	_	_
16	devoid	_	ADJ	_	Degree=Pos	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	AF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	AF	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	2	_	NUM	_	NumType=Card	_	_	_	_
27	supported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	transient	_	ADJ	_	Degree=Pos	_	_	_	_
30	outgrowth	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	erythroid	_	ADJ	_	Number=Sing	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	contrast	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	dominant	_	ADJ	_	Degree=Pos	_	_	_	_
9	interfering	_	VERB	_	VerbForm=Ger	_	_	_	_
10	deltaDNA	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	binding	_	VERB	_	Number=Sing	_	_	_	_
13	domain	_	NOUN	_	Number=Sing	_	_	_	_
14	RXR	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	deletion	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	entire	_	ADJ	_	Degree=Pos	_	_	_	_
22	DNA	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	binding	_	VERB	_	Number=Sing	_	_	_	_
25	domain	_	NOUN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
28	incompatible	_	ADJ	_	Degree=Pos	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	erythroid	_	NOUN	_	Degree=Pos	_	_	_	_
31	cell	_	NOUN	_	Number=Sing	_	_	_	_
32	growth	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	vitro	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	suggesting	_	VERB	_	VerbForm=Ger	_	_	_	_
37	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
38	pivotal	_	ADJ	_	Degree=Pos	_	_	_	_
39	role	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	RXR	_	NOUN	_	Number=Sing	_	_	_	_
42	for	_	ADP	_	_	_	_	_	_
43	erythroid	_	NOUN	_	Number=Sing	_	_	_	_
44	cell	_	NOUN	_	Number=Sing	_	_	_	_
45	development	_	NOUN	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013037	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Protease	_	NOUN	_	Number=Sing	_	_	_	_
2	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
3	block	_	NOUN	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	lipopolysaccharide	_	NOUN	_	Degree=Pos	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	tissue	_	NOUN	_	Degree=Pos	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	by	_	SCONJ	_	_	_	_	_	_
16	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	p65	_	NOUN	_	Number=Sing	_	_	_	_
22	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Tissue	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	TF	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	rapidly	_	ADV	_	_	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
12	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
15	endotoxin	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	LPS	_	NOUN	_	Number=Sing	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
9	/	_	PUNCT	_	_	_	_	_	_
10	p65	_	NOUN	_	Number=Sing	_	_	_	_
11	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	kappa	_	NOUN	_	Number=Sing	_	_	_	_
15	B	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	like	_	ADJ	_	Degree=Pos	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	TF	_	PROPN	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	translocation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	cytosolic	_	ADJ	_	Degree=Pos	_	_	_	_
5	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
6	/	_	PUNCT	_	_	_	_	_	_
7	p65	_	NOUN	_	Number=Sing	_	_	_	_
8	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	other	_	ADJ	_	Degree=Pos	_	_	_	_
11	members	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	Rel	_	PROPN	_	Number=Sing	_	_	_	_
20	family	_	NOUN	_	Number=Sing	_	_	_	_
21	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	degradation	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
32	kappa	_	VERB	_	Number=Sing	_	_	_	_
33	B	_	PROPN	_	Number=Sing	_	_	_	_
34	alpha	_	PROPN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	protease	_	NOUN	_	Number=Sing	_	_	_	_
3	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
4	N	_	PROPN	_	Number=Sing	_	_	_	_
5	alpha	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	tosylphenylalanyl	_	ADJ	_	Number=Sing	_	_	_	_
8	chloromethyl	_	NOUN	_	Number=Sing	_	_	_	_
9	ketone	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	TPCK	_	PROPN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	N	_	PROPN	_	Number=Sing	_	_	_	_
15	alpha	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	tosyl	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	L	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	lysine	_	NOUN	_	Number=Sing	_	_	_	_
22	chloromethyl	_	NOUN	_	Number=Sing	_	_	_	_
23	ketone	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	TLCK	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	block	_	NOUN	_	Number=Sing	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	kappa	_	NOUN	_	Number=Sing	_	_	_	_
33	B	_	NOUN	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	Rel	_	NOUN	_	Number=Sing	_	_	_	_
36	proteins	_	NOUN	_	Number=Plur	_	_	_	_
37	by	_	SCONJ	_	_	_	_	_	_
38	preventing	_	VERB	_	VerbForm=Ger	_	_	_	_
39	degradation	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
42	kappa	_	VERB	_	Number=Sing	_	_	_	_
43	B	_	PROPN	_	Number=Sing	_	_	_	_
44	alpha	_	PROPN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
3	if	_	SCONJ	_	_	_	_	_	_
4	TPCK	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	TLCK	_	PROPN	_	Number=Sing	_	_	_	_
7	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	LPS	_	PROPN	_	Number=Sing	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	TF	_	ADJ	_	Number=Sing	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	freshly	_	ADV	_	_	_	_	_	_
15	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
20	THP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	pretreated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	with	_	ADP	_	_	_	_	_	_
27	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
28	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
29	for	_	ADP	_	_	_	_	_	_
30	30	_	NUM	_	NumType=Card	_	_	_	_
31	min	_	NOUN	_	Number=Plur	_	_	_	_
32	before	_	ADP	_	_	_	_	_	_
33	LPS	_	PROPN	_	Number=Sing	_	_	_	_
34	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	TPCK	_	NOUN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	TLCK	_	PROPN	_	Number=Sing	_	_	_	_
5	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	LPS	_	PROPN	_	Number=Sing	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	TF	_	PROPN	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	TF	_	PROPN	_	Number=Sing	_	_	_	_
13	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	TF	_	PROPN	_	Number=Sing	_	_	_	_
16	promoter	_	NOUN	_	Number=Sing	_	_	_	_
17	activity	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	dose	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	manner	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
3	specifically	_	ADV	_	_	_	_	_	_
4	prevented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	degradation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	kappa	_	VERB	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	translocation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	p65	_	NOUN	_	Number=Sing	_	_	_	_
18	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	TPCK	_	PROPN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	TLCK	_	PROPN	_	Number=Sing	_	_	_	_
7	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	not	_	PART	_	_	_	_	_	_
9	block	_	VERB	_	VerbForm=Inf	_	_	_	_
10	induction	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	early	_	ADJ	_	Degree=Pos	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	transcription	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	Egr	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	data	_	NOUN	_	Number=Sing	_	_	_	_
6	indicated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
9	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
10	translocation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	c-Rel	_	NOUN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	p65	_	NOUN	_	Number=Sing	_	_	_	_
15	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
16	prevented	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	LPS	_	NOUN	_	Number=Sing	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	TF	_	ADJ	_	Number=Sing	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
25	cells	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013044	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	transcription	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	murine	_	NOUN	_	Number=Sing	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	ciprofloxacin	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	fluoroquinolone	_	NOUN	_	Number=Sing	_	_	_	_
3	antibiotic	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	ciprofloxacin	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	cipro	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	hyperproduction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	IL	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	2	_	NUM	_	NumType=Card	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	interferon	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	gamma	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	IFN	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	gamma	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	stimulated	_	VERB	_	Degree=Pos	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
33	blood	_	NOUN	_	Number=Sing	_	_	_	_
34	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	investigation	_	NOUN	_	Number=Sing	_	_	_	_
4	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	prolonged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	2	_	NUM	_	NumType=Card	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
16	response	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	also	_	ADV	_	_	_	_	_	_
19	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	both	_	DET	_	_	_	_	_	_
22	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	T	_	NOUN	_	NumType=Card	_	_	_	_
25	cell	_	NOUN	_	Number=Sing	_	_	_	_
26	mitogens	_	NOUN	_	Number=Plur	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	alloantigens	_	NOUN	_	Number=Plur	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	murine	_	NOUN	_	Number=Sing	_	_	_	_
31	splenocytes	_	NOUN	_	Number=Plur	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	stimulated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
36	murine	_	NOUN	_	Number=Sing	_	_	_	_
37	T	_	PROPN	_	Number=Sing	_	_	_	_
38	cell	_	NOUN	_	Number=Sing	_	_	_	_
39	line	_	NOUN	_	Number=Sing	_	_	_	_
40	EL	_	PROPN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	4	_	NUM	_	NumType=Card	_	_	_	_
43	in	_	ADP	_	_	_	_	_	_
44	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
45	presence	_	NOUN	_	Number=Sing	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	ciprofloxacin	_	NOUN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	5-80	_	NUM	_	NumType=Card	_	_	_	_
50	micrograms	_	NOUN	_	Number=Plur	_	_	_	_
51	/	_	PUNCT	_	_	_	_	_	_
52	ml	_	NOUN	_	Number=Sing	_	_	_	_
53	)	_	PUNCT	_	_	_	_	_	_
54	as	_	SCONJ	_	_	_	_	_	_
55	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
56	to	_	ADP	_	_	_	_	_	_
57	control	_	NOUN	_	VerbForm=Inf	_	_	_	_
58	cells	_	NOUN	_	Number=Plur	_	_	_	_
59	without	_	ADP	_	_	_	_	_	_
60	antibiotics	_	NOUN	_	Number=Plur	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	in	_	ADP	_	_	_	_	_	_
4	contrast	_	NOUN	_	Number=Sing	_	_	_	_
5	to	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	IFN	_	ADJ	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	gamma	_	NOUN	_	Number=Sing	_	_	_	_
12	production	_	NOUN	_	Number=Sing	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	IFN	_	ADJ	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	gamma	_	NOUN	_	Number=Sing	_	_	_	_
19	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
20	levels	_	NOUN	_	Number=Plur	_	_	_	_
21	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	unaffected	_	ADJ	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	at	_	ADP	_	_	_	_	_	_
24	24	_	NUM	_	NumType=Card	_	_	_	_
25	h	_	NOUN	_	Number=Plur	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	only	_	ADV	_	_	_	_	_	_
28	slightly	_	ADV	_	_	_	_	_	_
29	upregulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	at	_	ADP	_	_	_	_	_	_
31	48	_	NUM	_	NumType=Card	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	72	_	NUM	_	NumType=Card	_	_	_	_
34	h	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	culture	_	NOUN	_	Number=Sing	_	_	_	_
37	in	_	ADP	_	_	_	_	_	_
38	murine	_	NOUN	_	Number=Sing	_	_	_	_
39	splenocytes	_	NOUN	_	Number=Plur	_	_	_	_
40	incubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	with	_	ADP	_	_	_	_	_	_
42	cipro	_	NOUN	_	Number=Sing	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	20	_	NUM	_	NumType=Card	_	_	_	_
45	micrograms	_	NOUN	_	Number=Plur	_	_	_	_
46	/	_	PUNCT	_	_	_	_	_	_
47	ml	_	NOUN	_	Number=Sing	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	EL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	4	_	NUM	_	NumType=Card	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	transfected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	plasmid	_	NOUN	_	Number=Sing	_	_	_	_
10	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
18	region	_	NOUN	_	Number=Sing	_	_	_	_
19	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	chloramphenicol	_	PROPN	_	Number=Sing	_	_	_	_
23	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	CAT	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	reporter	_	NOUN	_	Number=Sing	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CAT	_	NOUN	_	Number=Sing	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	cipro	_	NOUN	_	Number=Sing	_	_	_	_
8	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	induction	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	EL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	4	_	NUM	_	NumType=Card	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	incubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	ciprofloxacin	_	NOUN	_	Number=Sing	_	_	_	_
11	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	early	_	ADJ	_	Degree=Pos	_	_	_	_
14	peak	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	more	_	ADV	_	_	_	_	_	_
17	activated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	as	_	SCONJ	_	_	_	_	_	_
30	compared	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	to	_	ADP	_	_	_	_	_	_
32	control	_	NOUN	_	VerbForm=Inf	_	_	_	_
33	cells	_	NOUN	_	Number=Plur	_	_	_	_
34	without	_	ADP	_	_	_	_	_	_
35	antibiotics	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Cipro	_	PROPN	_	Number=Sing	_	_	_	_
2	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	not	_	PART	_	_	_	_	_	_
4	affect	_	VERB	_	VerbForm=Inf	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factors	_	NOUN	_	Number=Plur	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	NFIL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2A	_	NOUN	_	Number=Sing	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	Taken	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	together	_	ADV	_	_	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	cipro	_	PROPN	_	Number=Sing	_	_	_	_
5	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	IFN	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	gamma	_	NOUN	_	Number=Sing	_	_	_	_
9	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	production	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	murine	_	NOUN	_	Number=Sing	_	_	_	_
19	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
20	by	_	ADP	_	_	_	_	_	_
21	means	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	SCONJ	_	_	_	_	_	_
23	influencing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	causing	_	VERB	_	VerbForm=Ger	_	_	_	_
29	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
30	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	IL	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	2	_	NUM	_	NumType=Card	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013046	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	12	_	NUM	_	NumType=Card	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	B	_	ADJ	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	transformation	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	Barr	_	PROPN	_	Number=Sing	_	_	_	_
14	virus	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	interleukin	_	PROPN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	12	_	NUM	_	NumType=Card	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	originally	_	ADV	_	_	_	_	_	_
10	purified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	Epstein	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	Barr	_	PROPN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	EBV	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	B	_	PROPN	_	Number=Sing	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	high	_	ADJ	_	Degree=Pos	_	_	_	_
27	correlation	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	EBV	_	PROPN	_	Number=Sing	_	_	_	_
30	infection	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	IL	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	12	_	NUM	_	NumType=Card	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
38	suggested	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	no	_	DET	_	_	_	_	_	_
41	study	_	NOUN	_	Number=Sing	_	_	_	_
42	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
43	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	whether	_	SCONJ	_	_	_	_	_	_
45	EBV	_	PROPN	_	Number=Sing	_	_	_	_
46	infection	_	NOUN	_	Number=Sing	_	_	_	_
47	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
48	directly	_	ADV	_	_	_	_	_	_
49	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
50	to	_	ADP	_	_	_	_	_	_
51	IL	_	PROPN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	12	_	NUM	_	NumType=Card	_	_	_	_
54	expression	_	NOUN	_	Number=Sing	_	_	_	_
55	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	address	_	VERB	_	VerbForm=Inf	_	_	_	_
3	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
4	issue	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	IL	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	12	_	NUM	_	NumType=Card	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	B	_	ADJ	_	Degree=Pos	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	during	_	ADP	_	_	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	vitro	_	NOUN	_	Number=Sing	_	_	_	_
19	transformation	_	NOUN	_	Number=Sing	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	EBV	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	peripheral	_	NOUN	_	Number=Sing	_	_	_	_
3	B	_	NOUN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	became	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	capable	_	ADJ	_	Degree=Pos	_	_	_	_
7	of	_	SCONJ	_	_	_	_	_	_
8	constitutively	_	ADV	_	_	_	_	_	_
9	producing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	p40	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	vitro	_	NOUN	_	Number=Sing	_	_	_	_
14	transformation	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	EBV	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	coincident	_	ADJ	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	latent	_	ADJ	_	Degree=Pos	_	_	_	_
24	membrane	_	NOUN	_	Number=Sing	_	_	_	_
25	protein	_	NOUN	_	Number=Sing	_	_	_	_
26	1	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	LMP1	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	EBV	_	PROPN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	B	_	NOUN	_	Degree=Pos	_	_	_	_
3	cells	_	NOUN	_	Number=Plur	_	_	_	_
4	expressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	p40	_	NOUN	_	Number=Sing	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	p35	_	NUM	_	Number=Sing	_	_	_	_
8	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
12	myristate	_	NOUN	_	Number=Sing	_	_	_	_
13	acetate	_	NOUN	_	Number=Sing	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	PMA	_	PROPN	_	Number=Sing	_	_	_	_
16	)	_	PUNCT	_	_	_	_	_	_
17	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	strongly	_	ADV	_	_	_	_	_	_
19	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	p40	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	p70	_	NOUN	_	Number=Sing	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	transfection	_	NOUN	_	Number=Sing	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	vector	_	NOUN	_	Number=Sing	_	_	_	_
8	into	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	lymphoma	_	NOUN	_	Number=Sing	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	line	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	Daudi	_	PROPN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	led	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	p40	_	NOUN	_	Number=Sing	_	_	_	_
21	production	_	NOUN	_	Number=Sing	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	factor	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	transformation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	primary	_	ADJ	_	Degree=Pos	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	EBV	_	PROPN	_	Number=Sing	_	_	_	_
12	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	IL	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	12	_	NUM	_	NumType=Card	_	_	_	_
16	expression	_	NOUN	_	Number=Sing	_	_	_	_
17	potentially	_	ADV	_	_	_	_	_	_
18	through	_	ADP	_	_	_	_	_	_
19	LMP1	_	PROPN	_	Number=Sing	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Copyright	_	NOUN	_	Number=Sing	_	_	_	_
2	1998	_	NUM	_	NumType=Card	_	_	_	_
3	Academic	_	PROPN	_	Degree=Pos	_	_	_	_
4	Press	_	NOUN	_	Number=Sing	_	_	_	_
5	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013051	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Downstream	_	ADJ	_	Degree=Pos	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	TATA	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	less	_	ADJ	_	Degree=Cmp	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	Oct	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	Bob1	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
20	directs	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	homing	_	NOUN	_	Number=Sing	_	_	_	_
25	receptor	_	NOUN	_	Number=Sing	_	_	_	_
26	BLR1	_	PROPN	_	Number=Sing	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	mature	_	VERB	_	VerbForm=Inf	_	_	_	_
29	B	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	chemokine	_	NOUN	_	Number=Sing	_	_	_	_
3	receptor	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	BLR1	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	major	_	ADJ	_	Degree=Pos	_	_	_	_
10	regulator	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	microenvironmental	_	ADJ	_	Degree=Pos	_	_	_	_
14	homing	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	B	_	ADJ	_	Degree=Pos	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	lymphoid	_	ADJ	_	Degree=Pos	_	_	_	_
20	organs	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	identify	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	three	_	NUM	_	NumType=Card	_	_	_	_
6	essential	_	ADJ	_	Degree=Pos	_	_	_	_
7	elements	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	TATA	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	less	_	ADJ	_	Degree=Cmp	_	_	_	_
13	blr1	_	NOUN	_	Number=Sing	_	_	_	_
14	core	_	NOUN	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	that	_	PRON	_	PronType=Rel	_	_	_	_
17	confer	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	type	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	specific	_	ADJ	_	Degree=Pos	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	both	_	CCONJ	_	_	_	_	_	_
32	humans	_	NOUN	_	Number=Plur	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	mice	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	functional	_	ADJ	_	Degree=Pos	_	_	_	_
38	promoter	_	NOUN	_	Number=Sing	_	_	_	_
39	region	_	NOUN	_	Number=Sing	_	_	_	_
40	(	_	PUNCT	_	_	_	_	_	_
41	-	_	SYM	_	_	_	_	_	_
42	36	_	NUM	_	NumType=Card	_	_	_	_
43	with	_	ADP	_	_	_	_	_	_
44	respect	_	NOUN	_	Number=Sing	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	transcription	_	NOUN	_	Number=Sing	_	_	_	_
48	start	_	NOUN	_	Number=Sing	_	_	_	_
49	site	_	NOUN	_	Number=Sing	_	_	_	_
50	)	_	PUNCT	_	_	_	_	_	_
51	,	_	PUNCT	_	_	_	_	_	_
52	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
53	NF	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
56	motif	_	NOUN	_	Number=Sing	_	_	_	_
57	(	_	PUNCT	_	_	_	_	_	_
58	+	_	SYM	_	_	_	_	_	_
59	44	_	NUM	_	NumType=Card	_	_	_	_
60	)	_	PUNCT	_	_	_	_	_	_
61	,	_	PUNCT	_	_	_	_	_	_
62	and	_	CCONJ	_	_	_	_	_	_
63	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
64	noncanonical	_	ADJ	_	Degree=Pos	_	_	_	_
65	octamer	_	NOUN	_	Number=Sing	_	_	_	_
66	motif	_	NOUN	_	Number=Sing	_	_	_	_
67	(	_	PUNCT	_	_	_	_	_	_
68	+	_	SYM	_	_	_	_	_	_
69	157	_	NUM	_	NumType=Card	_	_	_	_
70	)	_	PUNCT	_	_	_	_	_	_
71	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	importance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	sites	_	NOUN	_	Number=Plur	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	confirmed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	vivo	_	PROPN	_	Number=Sing	_	_	_	_
11	studies	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	targeted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	mice	_	NOUN	_	Number=Plur	_	_	_	_
17	deficient	_	NOUN	_	Degree=Pos	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	either	_	CCONJ	_	_	_	_	_	_
20	Oct	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	Bob1	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	both	_	CCONJ	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	subunits	_	NOUN	_	Number=Plur	_	_	_	_
32	p50	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	p52	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	all	_	DET	_	_	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	animals	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	BLR1	_	PROPN	_	Number=Sing	_	_	_	_
11	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
12	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	absent	_	ADJ	_	Degree=Pos	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	mice	_	NOUN	_	Number=Plur	_	_	_	_
3	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
4	only	_	ADV	_	_	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	p52/NF	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	BLR1	_	PROPN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	unaffected	_	ADJ	_	Degree=Pos	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
3	data	_	NOUN	_	Number=Sing	_	_	_	_
4	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	BLR1	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	target	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	Oct	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	Bob1	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	members	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	/	_	PUNCT	_	_	_	_	_	_
26	Rel	_	NOUN	_	Number=Sing	_	_	_	_
27	family	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	provides	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
31	link	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	impaired	_	VERB	_	Degree=Pos	_	_	_	_
35	B	_	NOUN	_	Number=Sing	_	_	_	_
36	cell	_	NOUN	_	Number=Sing	_	_	_	_
37	functions	_	NOUN	_	Number=Plur	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	mice	_	NOUN	_	Number=Plur	_	_	_	_
40	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
41	for	_	ADP	_	_	_	_	_	_
42	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
43	factors	_	NOUN	_	Number=Plur	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013059	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Defective	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	impaired	_	ADJ	_	Degree=Pos	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	c	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	Fos	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	FosB	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	JunB	_	PROPN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	anergic	_	NOUN	_	Degree=Pos	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	helper	_	NOUN	_	Number=Sing	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Anergic	_	PROPN	_	Degree=Pos	_	_	_	_
2	CD4	_	PROPN	_	Number=Sing	_	_	_	_
3	+	_	SYM	_	_	_	_	_	_

1	Th	_	DET	_	_	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	not	_	PART	_	_	_	_	_	_
5	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	when	_	ADV	_	PronType=Int	_	_	_	_
10	challenged	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	Ag	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	pulsed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	accessory	_	ADJ	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	because	_	ADP	_	_	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	defect	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	work	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
9	anergic	_	ADJ	_	Degree=Pos	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	defective	_	ADJ	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	ability	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	up	_	VERB	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
21	protein	_	NOUN	_	Number=Sing	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
25	at	_	ADP	_	_	_	_	_	_
26	two	_	NUM	_	NumType=Card	_	_	_	_
27	critical	_	ADJ	_	Degree=Pos	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	2	_	NUM	_	NumType=Card	_	_	_	_
31	DNA	_	PROPN	_	Number=Sing	_	_	_	_
32	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
33	elements	_	NOUN	_	Number=Plur	_	_	_	_
34	:	_	PUNCT	_	_	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	AT	_	ADP	_	_	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
40	factor	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	T	_	NOUN	_	Number=Sing	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	;	_	PUNCT	_	_	_	_	_	_
46	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
47	sequence	_	NOUN	_	Number=Sing	_	_	_	_
48	that	_	PRON	_	PronType=Rel	_	_	_	_
49	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
50	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
51	heterotrimeric	_	ADJ	_	Degree=Pos	_	_	_	_
52	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	Fos	_	PROPN	_	Number=Sing	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	Jun	_	PROPN	_	Number=Sing	_	_	_	_
58	protein	_	NOUN	_	Number=Sing	_	_	_	_
59	complex	_	NOUN	_	Number=Sing	_	_	_	_
60	)	_	PUNCT	_	_	_	_	_	_
61	and	_	CCONJ	_	_	_	_	_	_
62	Activator	_	PROPN	_	Number=Sing	_	_	_	_
63	Protein	_	PROPN	_	Number=Sing	_	_	_	_
64	-	_	PUNCT	_	_	_	_	_	_
65	1	_	NUM	_	NumType=Card	_	_	_	_
66	(	_	PUNCT	_	_	_	_	_	_
67	AP	_	NOUN	_	Number=Sing	_	_	_	_
68	-	_	PUNCT	_	_	_	_	_	_
69	1	_	NUM	_	NumType=Card	_	_	_	_
70	)	_	PUNCT	_	_	_	_	_	_
71	(	_	PUNCT	_	_	_	_	_	_
72	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
73	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
74	Fos	_	NOUN	_	Number=Sing	_	_	_	_
75	and	_	CCONJ	_	_	_	_	_	_
76	Jun	_	PROPN	_	Number=Sing	_	_	_	_
77	heterodimers	_	NOUN	_	Number=Plur	_	_	_	_
78	)	_	PUNCT	_	_	_	_	_	_
79	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	extracts	_	NOUN	_	Number=Plur	_	_	_	_
7	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	impaired	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	DNA	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	interactions	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	anergic	_	ADJ	_	Degree=Pos	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	poor	_	ADJ	_	Degree=Pos	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	inducible	_	ADJ	_	Number=Sing	_	_	_	_
27	AP	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	family	_	NOUN	_	Number=Sing	_	_	_	_
31	members	_	NOUN	_	Number=Plur	_	_	_	_
32	c	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	Fos	_	PROPN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	FosB	_	PROPN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	JunB	_	PROPN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	proteins	_	NOUN	_	Number=Plur	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	not	_	PART	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	result	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	global	_	ADJ	_	Degree=Pos	_	_	_	_
16	TCR	_	NOUN	_	Number=Sing	_	_	_	_
17	/	_	PUNCT	_	_	_	_	_	_
18	CD3	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	signaling	_	NOUN	_	Number=Sing	_	_	_	_
21	defect	_	NOUN	_	Number=Sing	_	_	_	_
22	because	_	SCONJ	_	_	_	_	_	_
23	CD3	_	PROPN	_	Number=Sing	_	_	_	_
24	cross	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	linking	_	VERB	_	Number=Sing	_	_	_	_
27	induced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
28	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	equivalent	_	ADJ	_	Degree=Pos	_	_	_	_
30	increase	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	free	_	ADJ	_	Degree=Pos	_	_	_	_
35	calcium	_	NOUN	_	Number=Sing	_	_	_	_
36	ions	_	NOUN	_	Number=Plur	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	as	_	ADV	_	_	_	_	_	_
39	well	_	ADV	_	Degree=Pos	_	_	_	_
40	as	_	ADP	_	_	_	_	_	_
41	NFATp	_	NOUN	_	Degree=Pos	_	_	_	_
42	dephosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
43	,	_	PUNCT	_	_	_	_	_	_
44	translocation	_	NOUN	_	Number=Sing	_	_	_	_
45	to	_	ADP	_	_	_	_	_	_
46	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
47	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	and	_	CCONJ	_	_	_	_	_	_
50	DNA	_	PROPN	_	Number=Sing	_	_	_	_
51	binding	_	VERB	_	Number=Sing	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	both	_	CCONJ	_	_	_	_	_	_
54	normal	_	ADJ	_	Degree=Pos	_	_	_	_
55	and	_	CCONJ	_	_	_	_	_	_
56	anergic	_	ADJ	_	Degree=Pos	_	_	_	_
57	T	_	NOUN	_	Number=Sing	_	_	_	_
58	cells	_	NOUN	_	Number=Plur	_	_	_	_
59	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	defective	_	ADJ	_	Degree=Pos	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	be	_	AUX	_	VerbForm=Inf	_	_	_	_
12	due	_	ADP	_	_	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	at	_	ADV	_	_	_	_	_	_
15	least	_	ADV	_	Degree=Sup	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	part	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	selective	_	ADJ	_	Degree=Pos	_	_	_	_
22	block	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	expression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	AP	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	Fos	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	Jun	_	PROPN	_	Number=Sing	_	_	_	_
34	family	_	NOUN	_	Number=Sing	_	_	_	_
35	members	_	NOUN	_	Number=Plur	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	anergic	_	ADJ	_	Degree=Pos	_	_	_	_
38	T	_	NOUN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013060	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Structure	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	GATA3	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	.	_	PUNCT	_	_	_	_	_	_

1	GATA3	_	PROPN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	member	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	GATA	_	PROPN	_	Number=Sing	_	_	_	_
8	family	_	NOUN	_	Number=Sing	_	_	_	_
9	that	_	PRON	_	PronType=Rel	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	abundantly	_	ADV	_	_	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	T-lymphocyte	_	PROPN	_	Number=Sing	_	_	_	_
16	lineage	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	to	_	PART	_	_	_	_	_	_
21	participate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
24	receptor	_	NOUN	_	Number=Sing	_	_	_	_
25	gene	_	NOUN	_	Number=Sing	_	_	_	_
26	activation	_	NOUN	_	Number=Sing	_	_	_	_
27	through	_	ADP	_	_	_	_	_	_
28	binding	_	NOUN	_	Number=Sing	_	_	_	_
29	to	_	ADP	_	_	_	_	_	_
30	enhancers	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	understand	_	VERB	_	VerbForm=Inf	_	_	_	_
3	GATA3	_	PROPN	_	Degree=Pos	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	regulation	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
8	cloned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	5	_	NUM	_	NumType=Card	_	_	_	_
15	'	_	PUNCT	_	_	_	_	_	_
16	end	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	mouse	_	NOUN	_	Number=Sing	_	_	_	_
20	GATA3	_	NOUN	_	Degree=Pos	_	_	_	_
21	gene	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	GATA3	_	PROPN	_	Number=Sing	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	six	_	NUM	_	NumType=Card	_	_	_	_
10	exons	_	NOUN	_	Number=Plur	_	_	_	_
11	distributed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	over	_	ADP	_	_	_	_	_	_
13	17	_	NUM	_	NumType=Card	_	_	_	_
14	kb	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	DNA	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	human	_	ADJ	_	Degree=Pos	_	_	_	_
4	GATA3	_	NOUN	_	Number=Sing	_	_	_	_
5	zinc	_	NOUN	_	Number=Sing	_	_	_	_
6	fingers	_	NOUN	_	Number=Plur	_	_	_	_
7	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	encoded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	separate	_	ADJ	_	Degree=Pos	_	_	_	_
12	exons	_	NOUN	_	Number=Plur	_	_	_	_
13	highly	_	ADV	_	_	_	_	_	_
14	conserved	_	ADJ	_	Degree=Pos	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	GATA1	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	but	_	CCONJ	_	_	_	_	_	_
21	no	_	DET	_	_	_	_	_	_
22	other	_	ADJ	_	Degree=Pos	_	_	_	_
23	structural	_	ADJ	_	Degree=Pos	_	_	_	_
24	homologies	_	NOUN	_	Number=Plur	_	_	_	_
25	between	_	ADP	_	_	_	_	_	_
26	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
27	two	_	NUM	_	NumType=Card	_	_	_	_
28	genes	_	NOUN	_	Number=Plur	_	_	_	_
29	can	_	AUX	_	VerbForm=Fin	_	_	_	_
30	be	_	AUX	_	VerbForm=Inf	_	_	_	_
31	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	mouse	_	NOUN	_	Number=Sing	_	_	_	_
5	GATA3	_	PROPN	_	Number=Sing	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	units	_	NOUN	_	Number=Plur	_	_	_	_
8	start	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	at	_	ADP	_	_	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	major	_	ADJ	_	Degree=Pos	_	_	_	_
12	initiation	_	NOUN	_	Number=Sing	_	_	_	_
13	site	_	NOUN	_	Number=Sing	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	promoter	_	NOUN	_	Number=Sing	_	_	_	_
3	sequence	_	NOUN	_	Number=Sing	_	_	_	_
4	analysis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	two	_	NUM	_	NumType=Card	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
12	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
13	embedded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	within	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	CpG	_	PROPN	_	Number=Sing	_	_	_	_
17	island	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	share	_	VERB	_	VerbForm=Inf	_	_	_	_
20	structural	_	ADJ	_	Degree=Pos	_	_	_	_
21	features	_	NOUN	_	Number=Plur	_	_	_	_
22	often	_	ADV	_	_	_	_	_	_
23	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	promoters	_	NOUN	_	Number=Plur	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	housekeeping	_	NOUN	_	Number=Sing	_	_	_	_
29	genes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Finally	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	DNA	_	NOUN	_	Number=Sing	_	_	_	_
8	fragment	_	NOUN	_	Number=Sing	_	_	_	_
9	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	human	_	ADJ	_	Degree=Pos	_	_	_	_
12	GATA3	_	NOUN	_	Number=Sing	_	_	_	_
13	transcription	_	NOUN	_	Number=Sing	_	_	_	_
14	unit	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	3	_	NUM	_	NumType=Card	_	_	_	_
17	kb	_	NOUN	_	Number=Sing	_	_	_	_
18	upstream	_	NOUN	_	Number=Sing	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	initiation	_	NOUN	_	Number=Sing	_	_	_	_
22	site	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	kb	_	NOUN	_	Number=Sing	_	_	_	_
26	downstream	_	NOUN	_	Degree=Pos	_	_	_	_
27	from	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	polyadenylation	_	NOUN	_	Number=Sing	_	_	_	_
30	site	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	displays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
34	specificity	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013065	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Agonistic	_	ADJ	_	Degree=Pos	_	_	_	_
2	activity	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	CD40	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	single	_	ADJ	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	chain	_	NOUN	_	Number=Sing	_	_	_	_

1	Fv	_	NOUN	_	Number=Sing	_	_	_	_
2	constructed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	variable	_	ADJ	_	Degree=Pos	_	_	_	_
6	regions	_	NOUN	_	Number=Plur	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	mAb	_	PROPN	_	Number=Sing	_	_	_	_
9	G28	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	SYM	_	_	_	_	_	_
11	5	_	NUM	_	NumType=Card	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	single	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	chain	_	NOUN	_	Number=Sing	_	_	_	_
5	Fv	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	sFv	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	variable	_	ADJ	_	Degree=Pos	_	_	_	_
14	regions	_	NOUN	_	Number=Plur	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	CD40	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	mAb	_	NOUN	_	Number=Sing	_	_	_	_
21	G28	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	SYM	_	_	_	_	_	_
23	5	_	NUM	_	NumType=Card	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	molecule	_	NOUN	_	Number=Sing	_	_	_	_
3	bound	_	ADJ	_	Degree=Pos	_	_	_	_
4	CD40	_	PROPN	_	Number=Sing	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	high	_	ADJ	_	Degree=Pos	_	_	_	_
8	affinity	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	2.2	_	NUM	_	NumType=Card	_	_	_	_
11	nM	_	NOUN	_	Number=Sing	_	_	_	_
12	)	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	monomer	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	solution	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Surprisingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	G28-5	_	PROPN	_	Number=Sing	_	_	_	_
4	sFv	_	PROPN	_	Number=Sing	_	_	_	_
5	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	potent	_	ADJ	_	Number=Sing	_	_	_	_
8	CD40	_	PROPN	_	Number=Sing	_	_	_	_
9	agonist	_	NOUN	_	Number=Sing	_	_	_	_
10	that	_	PRON	_	PronType=Rel	_	_	_	_
11	rapidly	_	ADV	_	_	_	_	_	_
12	crosslinked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	CD40	_	NOUN	_	Number=Sing	_	_	_	_
14	on	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	surface	_	NOUN	_	Number=Sing	_	_	_	_
18	but	_	CCONJ	_	_	_	_	_	_
19	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	not	_	PART	_	_	_	_	_	_
21	crosslink	_	VERB	_	VerbForm=Inf	_	_	_	_
22	CD40	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	Ig	_	PROPN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	solution	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	G28-5	_	NUM	_	Number=Sing	_	_	_	_
2	sFv	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	more	_	ADV	_	_	_	_	_	_
6	potent	_	ADJ	_	Degree=Pos	_	_	_	_
7	agonist	_	ADJ	_	Number=Sing	_	_	_	_
8	than	_	ADP	_	_	_	_	_	_
9	G28-5	_	NUM	_	Number=Sing	_	_	_	_
10	IgG	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	able	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	stimulate	_	VERB	_	VerbForm=Inf	_	_	_	_
16	CD40	_	NOUN	_	Number=Sing	_	_	_	_
17	responses	_	NOUN	_	Number=Plur	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	B	_	ADJ	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	G28-5	_	NUM	_	Number=Sing	_	_	_	_
2	IgG	_	NOUN	_	Number=Sing	_	_	_	_
3	partially	_	ADV	_	_	_	_	_	_
4	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	whereas	_	SCONJ	_	_	_	_	_	_
7	G28	_	NUM	_	NumType=Card	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	5	_	NUM	_	NumType=Card	_	_	_	_
10	sFv	_	NOUN	_	Number=Sing	_	_	_	_
11	augmented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	CD40	_	NOUN	_	Number=Sing	_	_	_	_
13	responses	_	NOUN	_	Number=Plur	_	_	_	_
14	during	_	ADP	_	_	_	_	_	_
15	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	natural	_	ADJ	_	Degree=Pos	_	_	_	_
18	ligand	_	NOUN	_	Number=Sing	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	gp39	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	CD8	_	PROPN	_	Number=Sing	_	_	_	_
23	fusion	_	NOUN	_	Number=Sing	_	_	_	_
24	protein	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	functional	_	ADJ	_	Degree=Pos	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	ligands	_	NOUN	_	Number=Plur	_	_	_	_
10	built	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	G28	_	NUM	_	Number=Sing	_	_	_	_
17	-	_	SYM	_	_	_	_	_	_
18	5	_	NUM	_	NumType=Card	_	_	_	_
19	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	highly	_	ADV	_	_	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	upon	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	size	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	physical	_	ADJ	_	Degree=Pos	_	_	_	_
27	properties	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	molecule	_	NOUN	_	Number=Sing	_	_	_	_
31	both	_	CCONJ	_	_	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	solution	_	NOUN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	on	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	surfaces	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013069	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Stimulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
6	clone	_	NOUN	_	Number=Sing	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	anti-CD3	_	NOUN	_	Number=Sing	_	_	_	_
9	or	_	CCONJ	_	_	_	_	_	_
10	tumor	_	NOUN	_	Number=Sing	_	_	_	_
11	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	translocation	_	NOUN	_	Number=Sing	_	_	_	_
19	but	_	CCONJ	_	_	_	_	_	_
20	not	_	ADV	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
23	virus	_	NOUN	_	Number=Sing	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
28	transcription	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	transiently	_	ADV	_	_	_	_	_	_
5	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	vectors	_	NOUN	_	Number=Plur	_	_	_	_
8	under	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	control	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	long	_	ADJ	_	Degree=Pos	_	_	_	_
14	terminal	_	NOUN	_	Number=Sing	_	_	_	_
15	repeat	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	LTR	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
23	virus	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
29	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
30	sequence	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	translocation	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	HIV	_	PROPN	_	Number=Sing	_	_	_	_
37	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	binding	_	VERB	_	Number=Sing	_	_	_	_
40	protein	_	NOUN	_	Number=Sing	_	_	_	_
41	NF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	kappa	_	NOUN	_	Number=Sing	_	_	_	_

1	B	_	PRON	_	Number=Sing	_	_	_	_
2	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	two	_	NUM	_	NumType=Card	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
8	clones	_	NOUN	_	Number=Plur	_	_	_	_
9	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	through	_	ADP	_	_	_	_	_	_
11	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
12	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	complex	_	NOUN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	tumor	_	NOUN	_	Number=Sing	_	_	_	_
18	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
22	12	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	myristate	_	NOUN	_	Number=Sing	_	_	_	_
25	13	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	acetate	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	dissociation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	translocation	_	NOUN	_	Number=Sing	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	either	_	CCONJ	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	HIV	_	PROPN	_	Number=Sing	_	_	_	_
17	LTR	_	NOUN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	2	_	NUM	_	NumType=Card	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
5	but	_	CCONJ	_	_	_	_	_	_
6	not	_	ADV	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	translocation	_	NOUN	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	LTR	_	NOUN	_	Number=Sing	_	_	_	_
14	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Phorbol	_	NOUN	_	Number=Sing	_	_	_	_
2	ester	_	NOUN	_	Number=Sing	_	_	_	_
3	or	_	CCONJ	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	antigen	_	NOUN	_	Degree=Pos	_	_	_	_
6	recognition	_	NOUN	_	Number=Sing	_	_	_	_
7	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	HIV	_	NOUN	_	Number=Sing	_	_	_	_
9	LTR	_	NOUN	_	Number=Sing	_	_	_	_
10	transactivation	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	whereas	_	SCONJ	_	_	_	_	_	_
13	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	tumor	_	NOUN	_	Number=Sing	_	_	_	_
16	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	or	_	CCONJ	_	_	_	_	_	_
19	antibody	_	NOUN	_	Number=Sing	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	CD3	_	PROPN	_	Number=Sing	_	_	_	_
22	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	two	_	NUM	_	NumType=Card	_	_	_	_
3	latter	_	ADJ	_	Degree=Pos	_	_	_	_
4	signals	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	nevertheless	_	ADV	_	_	_	_	_	_
7	able	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	translocation	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	pattern	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	band	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	shift	_	NOUN	_	Number=Sing	_	_	_	_
23	assay	_	NOUN	_	Number=Sing	_	_	_	_
24	indistinguishable	_	ADJ	_	Degree=Pos	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
27	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	using	_	VERB	_	VerbForm=Ger	_	_	_	_
29	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
30	ester	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	finding	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	DET	_	_	_	_	_	_
4	induction	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	by	_	ADP	_	_	_	_	_	_
11	tumor	_	NOUN	_	Number=Sing	_	_	_	_
12	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
13	factor	_	NOUN	_	Number=Sing	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	antibody	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	CD3	_	PROPN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	not	_	PART	_	_	_	_	_	_
20	sufficient	_	ADJ	_	Degree=Pos	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
23	HIV	_	NOUN	_	Number=Sing	_	_	_	_
24	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	cloned	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
30	T	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	contrasts	_	VERB	_	Number=Plur	_	_	_	_
33	with	_	ADP	_	_	_	_	_	_
34	results	_	NOUN	_	Number=Plur	_	_	_	_
35	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	most	_	ADJ	_	_	_	_	_	_
38	lymphoblastoid	_	ADJ	_	Degree=Pos	_	_	_	_
39	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
40	lines	_	NOUN	_	Number=Plur	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	indicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
43	that	_	SCONJ	_	_	_	_	_	_
44	normal	_	ADJ	_	Degree=Pos	_	_	_	_
45	T	_	NOUN	_	Number=Sing	_	_	_	_
46	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
47	differ	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
48	from	_	ADP	_	_	_	_	_	_
49	tumoral	_	ADJ	_	Degree=Pos	_	_	_	_
50	T	_	NOUN	_	Number=Sing	_	_	_	_
51	cells	_	NOUN	_	Number=Plur	_	_	_	_
52	in	_	ADP	_	_	_	_	_	_
53	terms	_	NOUN	_	Number=Plur	_	_	_	_
54	of	_	ADP	_	_	_	_	_	_
55	requirements	_	NOUN	_	Number=Plur	_	_	_	_
56	for	_	ADP	_	_	_	_	_	_
57	HIV	_	NOUN	_	Number=Sing	_	_	_	_
58	LTR	_	NOUN	_	Number=Sing	_	_	_	_
59	activation	_	NOUN	_	Number=Sing	_	_	_	_
60	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	results	_	NOUN	_	Number=Plur	_	_	_	_
5	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	events	_	NOUN	_	Number=Plur	_	_	_	_
8	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	addition	_	NOUN	_	Number=Sing	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	translocation	_	NOUN	_	Number=Sing	_	_	_	_
23	per	_	ADP	_	_	_	_	_	_
24	se	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
27	functional	_	ADJ	_	Degree=Pos	_	_	_	_
28	interactions	_	NOUN	_	Number=Plur	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	NF	_	PROPN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	kappa	_	NOUN	_	Number=Sing	_	_	_	_
34	B	_	NOUN	_	Number=Sing	_	_	_	_
35	complex	_	NOUN	_	Number=Sing	_	_	_	_
36	with	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	HIV	_	NOUN	_	Number=Sing	_	_	_	_
39	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013073	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	tax	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	abrogates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	2	_	NUM	_	NumType=Card	_	_	_	_
13	dependence	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	mouse	_	NOUN	_	Number=Sing	_	_	_	_
17	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
18	line	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Human	_	ADJ	_	Degree=Pos	_	_	_	_
2	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
3	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
4	virus	_	NOUN	_	Number=Sing	_	_	_	_
5	type	_	NOUN	_	Number=Sing	_	_	_	_
6	1	_	NUM	_	NumType=Card	_	_	_	_
7	(	_	PUNCT	_	_	_	_	_	_
8	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	etiologic	_	ADJ	_	Degree=Pos	_	_	_	_
15	agent	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	adult	_	NOUN	_	Number=Sing	_	_	_	_
18	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
19	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	viral	_	ADJ	_	Degree=Pos	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	thought	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	be	_	AUX	_	VerbForm=Inf	_	_	_	_
11	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	development	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	disease	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	since	_	SCONJ	_	_	_	_	_	_
20	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
21	transforms	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	healthy	_	ADJ	_	Degree=Pos	_	_	_	_
23	T	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vitro	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	tumors	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	transgenic	_	ADJ	_	Degree=Pos	_	_	_	_
32	animals	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effect	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	Tax	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	growth	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	2	_	NUM	_	NumType=Card	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
23	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
24	line	_	NOUN	_	Number=Sing	_	_	_	_
25	CTLL	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Stable	_	ADJ	_	Degree=Pos	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Tax	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	CTLL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	2	_	NUM	_	NumType=Card	_	_	_	_
9	transformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	growth	_	NOUN	_	Number=Sing	_	_	_	_
12	from	_	SCONJ	_	_	_	_	_	_
13	being	_	AUX	_	VerbForm=Ger	_	_	_	_
14	IL	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	2	_	NUM	_	NumType=Card	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	2	_	NUM	_	NumType=Card	_	_	_	_
22	independent	_	ADJ	_	Degree=Pos	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Tax	_	NOUN	_	Number=Sing	_	_	_	_
2	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	through	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cyclic	_	ADJ	_	Number=Sing	_	_	_	_
11	AMP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	like	_	ADP	_	Degree=Pos	_	_	_	_
17	sequence	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	finding	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Tax	_	NOUN	_	Number=Sing	_	_	_	_
5	mutants	_	NOUN	_	Number=Plur	_	_	_	_
6	segregating	_	VERB	_	VerbForm=Ger	_	_	_	_
7	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
8	two	_	NUM	_	NumType=Card	_	_	_	_
9	pathways	_	NOUN	_	Number=Plur	_	_	_	_
10	suggested	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	that	_	SCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	pathway	_	NOUN	_	Number=Sing	_	_	_	_
17	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
18	essential	_	ADJ	_	Degree=Pos	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	independent	_	ADJ	_	Degree=Pos	_	_	_	_
25	growth	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	CTLL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	2	_	NUM	_	NumType=Card	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	while	_	SCONJ	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	CRE	_	NOUN	_	Number=Sing	_	_	_	_
34	pathway	_	NOUN	_	Number=Sing	_	_	_	_
35	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
36	unnecessary	_	ADJ	_	Degree=Pos	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	both	_	DET	_	_	_	_	_	_
4	pathways	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	necessary	_	ADJ	_	Degree=Pos	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	another	_	DET	_	_	_	_	_	_
9	transformation	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	related	_	ADJ	_	Degree=Pos	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	colony	_	NOUN	_	Number=Sing	_	_	_	_
15	formation	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	soft	_	ADJ	_	Number=Sing	_	_	_	_
18	agar	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	CTLL	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	2/Tax	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	Tax	_	NOUN	_	Number=Sing	_	_	_	_
6	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	at	_	ADV	_	_	_	_	_	_
8	least	_	ADV	_	Degree=Sup	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
11	activities	_	NOUN	_	Number=Plur	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	that	_	SCONJ	_	_	_	_	_	_
19	Tax	_	NOUN	_	Number=Sing	_	_	_	_
20	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	crucial	_	ADJ	_	Degree=Pos	_	_	_	_
23	role	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	IL	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	independent	_	ADJ	_	Degree=Pos	_	_	_	_
30	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
31	transformation	_	NOUN	_	Number=Sing	_	_	_	_
32	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	by	_	ADP	_	_	_	_	_	_
34	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	addition	_	NOUN	_	Number=Sing	_	_	_	_
40	to	_	ADP	_	_	_	_	_	_
41	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
42	well	_	ADV	_	Degree=Pos	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	IL	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	2	_	NUM	_	NumType=Card	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
50	cell	_	NOUN	_	Number=Sing	_	_	_	_
51	transformation	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013074	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Lipopolysaccharide	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	E-selectin	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	continuous	_	ADJ	_	Degree=Pos	_	_	_	_
8	presence	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	LPS	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	bactericidal	_	ADJ	_	Degree=Pos	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	permeability	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	LPS	_	PROPN	_	Number=Sing	_	_	_	_
6	express	_	NOUN	_	Number=Sing	_	_	_	_
7	E	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	selectin	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	which	_	PRON	_	PronType=Rel	_	_	_	_
12	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	important	_	ADJ	_	Degree=Pos	_	_	_	_
15	role	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	SCONJ	_	_	_	_	_	_
17	mediating	_	VERB	_	VerbForm=Ger	_	_	_	_
18	neutrophil	_	ADJ	_	Degree=Pos	_	_	_	_
19	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
20	during	_	ADP	_	_	_	_	_	_
21	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	E-selectin	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	within	_	ADP	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	SYM	_	_	_	_	_	_
7	2	_	NUM	_	NumType=Card	_	_	_	_
8	h	_	NOUN	_	Number=Plur	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	peaks	_	NOUN	_	Number=Plur	_	_	_	_
11	at	_	ADP	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	-	_	SYM	_	_	_	_	_	_
14	6	_	NUM	_	NumType=Card	_	_	_	_
15	h	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	gradually	_	ADV	_	_	_	_	_	_
19	returns	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	to	_	ADP	_	_	_	_	_	_
21	basal	_	ADJ	_	Degree=Pos	_	_	_	_
22	level	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	ADP	_	_	_	_	_	_
24	24	_	NUM	_	NumType=Card	_	_	_	_
25	h.	_	PROPN	_	Number=Sing	_	_	_	_
26	rBPI21	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
30	N	_	X	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	terminal	_	ADJ	_	Degree=Pos	_	_	_	_
33	fragment	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	human	_	ADJ	_	Degree=Pos	_	_	_	_
36	bactericidal	_	NOUN	_	Number=Sing	_	_	_	_
37	/	_	PUNCT	_	_	_	_	_	_
38	permeability	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	increasing	_	VERB	_	VerbForm=Ger	_	_	_	_
41	protein	_	NOUN	_	Number=Sing	_	_	_	_
42	(	_	PUNCT	_	_	_	_	_	_
43	BPI	_	NOUN	_	Number=Sing	_	_	_	_
44	)	_	PUNCT	_	_	_	_	_	_
45	,	_	PUNCT	_	_	_	_	_	_
46	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
47	LPS	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
50	E-selectin	_	PROPN	_	Number=Sing	_	_	_	_
51	expression	_	NOUN	_	Number=Sing	_	_	_	_
52	when	_	ADV	_	PronType=Int	_	_	_	_
53	added	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
54	at	_	ADP	_	_	_	_	_	_
55	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
56	same	_	ADJ	_	Degree=Pos	_	_	_	_
57	time	_	NOUN	_	Number=Sing	_	_	_	_
58	as	_	ADP	_	_	_	_	_	_
59	,	_	PUNCT	_	_	_	_	_	_
60	and	_	CCONJ	_	_	_	_	_	_
61	up	_	ADP	_	_	_	_	_	_
62	to	_	ADP	_	_	_	_	_	_
63	6	_	NUM	_	NumType=Card	_	_	_	_
64	h	_	NOUN	_	Number=Plur	_	_	_	_
65	after	_	ADV	_	_	_	_	_	_
66	,	_	PUNCT	_	_	_	_	_	_
67	LPS	_	PROPN	_	Number=Sing	_	_	_	_
68	.	_	PUNCT	_	_	_	_	_	_

1	Delayed	_	ADJ	_	Degree=Pos	_	_	_	_
2	administration	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	rBPI21	_	NOUN	_	Number=Sing	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	LPS	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	PROPN	_	Number=Sing	_	_	_	_
19	B.	_	PROPN	_	Number=Sing	_	_	_	_
20	Two	_	NUM	_	NumType=Card	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	4	_	NUM	_	NumType=Card	_	_	_	_
23	h	_	NOUN	_	Number=Sing	_	_	_	_
24	following	_	VERB	_	VerbForm=Ger	_	_	_	_
25	LPS	_	PROPN	_	Number=Sing	_	_	_	_
26	addition	_	NOUN	_	Number=Sing	_	_	_	_
27	to	_	ADP	_	_	_	_	_	_
28	endothelial	_	NOUN	_	Degree=Pos	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	when	_	ADV	_	PronType=Int	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	kappa	_	PROPN	_	Number=Sing	_	_	_	_
35	B	_	PROPN	_	Number=Sing	_	_	_	_
36	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
37	already	_	ADV	_	_	_	_	_	_
38	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	addition	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	rBPI21	_	NOUN	_	Number=Sing	_	_	_	_
43	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	marked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	reduction	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	NF	_	PROPN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	kappa	_	NOUN	_	Number=Sing	_	_	_	_
51	B	_	NOUN	_	Number=Sing	_	_	_	_
52	detectable	_	ADJ	_	Number=Sing	_	_	_	_
53	at	_	ADP	_	_	_	_	_	_
54	4	_	NUM	_	NumType=Card	_	_	_	_
55	or	_	CCONJ	_	_	_	_	_	_
56	6	_	NUM	_	NumType=Card	_	_	_	_
57	h	_	NOUN	_	Number=Plur	_	_	_	_
58	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	requires	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	continuous	_	ADJ	_	Degree=Pos	_	_	_	_
9	presence	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	LPS	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	rBPI21	_	VERB	_	Number=Sing	_	_	_	_
15	acts	_	NOUN	_	Number=Plur	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	reverse	_	VERB	_	VerbForm=Inf	_	_	_	_
18	LPS	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	mediated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	endothelial	_	ADJ	_	Degree=Pos	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	by	_	SCONJ	_	_	_	_	_	_
24	interrupting	_	VERB	_	VerbForm=Ger	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	going	_	VERB	_	VerbForm=Ger	_	_	_	_
29	LPS	_	NOUN	_	Number=Sing	_	_	_	_
30	signal	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013080	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Soluble	_	ADJ	_	Degree=Pos	_	_	_	_
2	tumor	_	NOUN	_	Number=Sing	_	_	_	_
3	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
4	factor	_	NOUN	_	Number=Sing	_	_	_	_
5	receptors	_	NOUN	_	Number=Plur	_	_	_	_
6	inhibit	_	VERB	_	Number=Sing	_	_	_	_
7	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
8	myristate	_	NOUN	_	Number=Sing	_	_	_	_
9	acetate	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	HIV	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	expression	_	NOUN	_	Number=Sing	_	_	_	_
18	chronically	_	ADV	_	_	_	_	_	_
19	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	U1	_	PROPN	_	Number=Sing	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	tumor	_	NOUN	_	Number=Sing	_	_	_	_
4	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	protein	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	r	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	h	_	NOUN	_	Number=Sing	_	_	_	_
17	TBP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	recombinant	_	ADJ	_	Degree=Pos	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	soluble	_	ADJ	_	Number=Sing	_	_	_	_
25	dimeric	_	ADJ	_	Degree=Pos	_	_	_	_
26	TNF	_	PROPN	_	Number=Sing	_	_	_	_
27	receptor	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	rhu	_	X	_	Number=Sing	_	_	_	_
30	TNFR	_	NOUN	_	Number=Sing	_	_	_	_
31	:	_	PUNCT	_	_	_	_	_	_
32	Fc	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
35	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
36	to	_	PART	_	_	_	_	_	_
37	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	relative	_	ADJ	_	Degree=Pos	_	_	_	_
40	contributions	_	NOUN	_	Number=Plur	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	TNF	_	NOUN	_	Number=Sing	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
45	myristate	_	NOUN	_	Number=Sing	_	_	_	_
46	acetate	_	NOUN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	PMA	_	PROPN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	and	_	CCONJ	_	_	_	_	_	_
51	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
52	-	_	PUNCT	_	_	_	_	_	_
53	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
54	human	_	ADJ	_	Degree=Pos	_	_	_	_
55	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
56	virus	_	NOUN	_	Number=Sing	_	_	_	_
57	type	_	NOUN	_	Number=Sing	_	_	_	_
58	1	_	NUM	_	NumType=Card	_	_	_	_
59	(	_	PUNCT	_	_	_	_	_	_
60	HIV	_	NOUN	_	Number=Sing	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	1	_	NUM	_	NumType=Card	_	_	_	_
63	)	_	PUNCT	_	_	_	_	_	_
64	replication	_	NOUN	_	Number=Sing	_	_	_	_
65	in	_	ADP	_	_	_	_	_	_
66	chronically	_	ADV	_	_	_	_	_	_
67	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
68	cell	_	NOUN	_	Number=Sing	_	_	_	_
69	lines	_	NOUN	_	Number=Plur	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	Treatment	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HIV	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	promonocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	U1	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	r-h-	_	PUNCT	_	_	_	_	_	_
13	TBP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	or	_	CCONJ	_	_	_	_	_	_
17	rhu	_	PROPN	_	Number=Sing	_	_	_	_
18	TNFR	_	NOUN	_	Number=Sing	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	Fc	_	PROPN	_	Number=Sing	_	_	_	_
21	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	PMA	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	p24	_	NUM	_	Number=Sing	_	_	_	_
29	antigen	_	NOUN	_	Number=Sing	_	_	_	_
30	production	_	NOUN	_	Number=Sing	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	concentration	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
36	manner	_	NOUN	_	Number=Sing	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
40	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
41	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
42	of	_	ADP	_	_	_	_	_	_
43	approximately	_	ADV	_	_	_	_	_	_
44	90	_	NUM	_	NumType=Card	_	_	_	_
45	%	_	SYM	_	Number=Sing	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	Maximal	_	ADJ	_	Degree=Pos	_	_	_	_
2	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	p24	_	NOUN	_	Number=Sing	_	_	_	_
5	antigen	_	NOUN	_	Number=Sing	_	_	_	_
6	production	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	T-lymphocytic	_	ADJ	_	Degree=Pos	_	_	_	_
9	ACH	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	2	_	NUM	_	NumType=Card	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
14	47	_	NUM	_	NumType=Card	_	_	_	_
15	%	_	SYM	_	Number=Sing	_	_	_	_
16	with	_	ADP	_	_	_	_	_	_
17	r-hTBP	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	42	_	NUM	_	NumType=Card	_	_	_	_
22	%	_	SYM	_	Number=Sing	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	rhu	_	PROPN	_	Number=Sing	_	_	_	_
25	TNFR	_	NOUN	_	Number=Sing	_	_	_	_
26	:	_	PUNCT	_	_	_	_	_	_
27	Fc.	_	PROPN	_	Number=Sing	_	_	_	_
28	r-hTBP	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	rhu	_	PROPN	_	Number=Sing	_	_	_	_
33	TNFR	_	NOUN	_	Number=Sing	_	_	_	_
34	:	_	PUNCT	_	_	_	_	_	_
35	Fc	_	PROPN	_	Number=Sing	_	_	_	_
36	also	_	ADV	_	_	_	_	_	_
37	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	p24	_	NUM	_	Number=Sing	_	_	_	_
39	antigen	_	NOUN	_	Number=Sing	_	_	_	_
40	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	by	_	ADP	_	_	_	_	_	_
42	U1	_	PROPN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	response	_	NOUN	_	Number=Sing	_	_	_	_
46	to	_	ADP	_	_	_	_	_	_
47	other	_	ADJ	_	Degree=Pos	_	_	_	_
48	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
49	,	_	PUNCT	_	_	_	_	_	_
50	including	_	VERB	_	VerbForm=Ger	_	_	_	_
51	phytohemagglutinin	_	NOUN	_	Number=Sing	_	_	_	_
52	(	_	PUNCT	_	_	_	_	_	_
53	PHA	_	NOUN	_	Number=Sing	_	_	_	_
54	)	_	PUNCT	_	_	_	_	_	_
55	-	_	PUNCT	_	_	_	_	_	_
56	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
57	supernatant	_	NOUN	_	Number=Sing	_	_	_	_
58	,	_	PUNCT	_	_	_	_	_	_
59	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
60	-	_	PUNCT	_	_	_	_	_	_
61	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
62	colony	_	NOUN	_	Number=Sing	_	_	_	_
63	-	_	PUNCT	_	_	_	_	_	_
64	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
65	factor	_	NOUN	_	Number=Sing	_	_	_	_
66	,	_	PUNCT	_	_	_	_	_	_
67	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
68	-	_	PUNCT	_	_	_	_	_	_
69	6	_	NUM	_	NumType=Card	_	_	_	_
70	,	_	PUNCT	_	_	_	_	_	_
71	and	_	CCONJ	_	_	_	_	_	_
72	TNF	_	NOUN	_	Number=Sing	_	_	_	_
73	.	_	PUNCT	_	_	_	_	_	_

1	Addition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	r-hTBP	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	to	_	ADP	_	_	_	_	_	_
7	U1	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	during	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	last	_	ADJ	_	Degree=Pos	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	h	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	24	_	NUM	_	NumType=Card	_	_	_	_
17	h	_	NOUN	_	Number=Sing	_	_	_	_
18	incubation	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	PMA	_	PROPN	_	Number=Sing	_	_	_	_
21	still	_	ADV	_	_	_	_	_	_
22	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
23	p24	_	NUM	_	Number=Sing	_	_	_	_
24	antigen	_	NOUN	_	Number=Sing	_	_	_	_
25	production	_	NOUN	_	Number=Sing	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	15	_	NUM	_	NumType=Card	_	_	_	_
28	%	_	SYM	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	U1	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	10	_	NUM	_	NumType=Card	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	7	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	M	_	PROPN	_	NumType=Card	_	_	_	_
11	PMA	_	PROPN	_	Number=Sing	_	_	_	_
12	released	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	approximately	_	ADV	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	ng	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	ml	_	NOUN	_	Number=Sing	_	_	_	_
18	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
19	TBP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	with	_	ADP	_	_	_	_	_	_
23	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	initial	_	ADJ	_	Degree=Pos	_	_	_	_
25	peak	_	NOUN	_	Number=Sing	_	_	_	_
26	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	at	_	ADP	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	h	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
33	peak	_	NOUN	_	Number=Sing	_	_	_	_
34	at	_	ADP	_	_	_	_	_	_
35	24	_	NUM	_	NumType=Card	_	_	_	_
36	h	_	NOUN	_	Number=Sing	_	_	_	_
37	after	_	ADP	_	_	_	_	_	_
38	PMA	_	PROPN	_	Number=Sing	_	_	_	_
39	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	r-hTBP	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	also	_	ADV	_	_	_	_	_	_
5	partially	_	ADV	_	_	_	_	_	_
6	reversed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	U1	_	PROPN	_	Number=Sing	_	_	_	_
10	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
12	caused	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	PMA	_	PROPN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	CCONJ	_	_	_	_	_	_
2	r-hTBP	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	rhu	_	PROPN	_	Number=Sing	_	_	_	_
7	TNFR	_	NOUN	_	Number=Sing	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	Fc	_	PROPN	_	Number=Sing	_	_	_	_
10	blocked	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	PMA	_	PROPN	_	Number=Sing	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	NK	_	PROPN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	DNA	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	binding	_	VERB	_	Number=Sing	_	_	_	_
25	activity	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	U1	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	association	_	NOUN	_	Number=Sing	_	_	_	_
31	with	_	ADP	_	_	_	_	_	_
32	decreases	_	NOUN	_	Number=Plur	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	HIV	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	replication	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	conclude	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
5	TNF	_	NOUN	_	Number=Sing	_	_	_	_
6	receptors	_	NOUN	_	Number=Plur	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
9	stimuli	_	ADJ	_	Degree=Pos	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	HIV	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	NK	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	PROPN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	DNA	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	binding	_	VERB	_	Number=Sing	_	_	_	_
24	activity	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	chronically	_	ADV	_	_	_	_	_	_
27	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	U1	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013083	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	basis	_	NOUN	_	Number=Sing	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	hyporesponsiveness	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
9	nitric	_	ADJ	_	Degree=Pos	_	_	_	_
10	oxide	_	NOUN	_	Number=Sing	_	_	_	_
11	synthase	_	NOUN	_	Number=Sing	_	_	_	_
12	gene	_	NOUN	_	Number=Sing	_	_	_	_
13	to	_	ADP	_	_	_	_	_	_
14	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	interferon	_	NOUN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	gamma	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	work	_	NOUN	_	Number=Sing	_	_	_	_
3	reported	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	here	_	ADV	_	PronType=Dem	_	_	_	_
5	resolves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	at	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	level	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	controversy	_	NOUN	_	Number=Sing	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	to	_	SCONJ	_	_	_	_	_	_
18	whether	_	SCONJ	_	_	_	_	_	_
19	or	_	CCONJ	_	_	_	_	_	_
20	not	_	ADV	_	_	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
25	can	_	AUX	_	VerbForm=Fin	_	_	_	_
26	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
27	nitric	_	ADJ	_	Degree=Pos	_	_	_	_
28	oxide	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	NO	_	INTJ	_	_	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	when	_	ADV	_	PronType=Int	_	_	_	_
33	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	lipopolysaccharide	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	LPS	_	NOUN	_	Number=Sing	_	_	_	_
38	)	_	PUNCT	_	_	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	or	_	CCONJ	_	_	_	_	_	_
42	without	_	ADP	_	_	_	_	_	_
43	co-stimulation	_	NOUN	_	Number=Sing	_	_	_	_
44	by	_	ADP	_	_	_	_	_	_
45	interferon	_	NOUN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	gamma	_	NOUN	_	Number=Sing	_	_	_	_
48	(	_	PUNCT	_	_	_	_	_	_
49	IFN	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	gamma	_	NOUN	_	Number=Sing	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	.	_	PUNCT	_	_	_	_	_	_

1	Studies	_	NOUN	_	Number=Plur	_	_	_	_
2	included	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	structural	_	ADJ	_	Degree=Pos	_	_	_	_
4	comparison	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	promoters	_	NOUN	_	Number=Plur	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	mouse	_	NOUN	_	Number=Sing	_	_	_	_
12	inducible	_	ADJ	_	Number=Sing	_	_	_	_
13	NO	_	DET	_	_	_	_	_	_
14	synthase	_	NOUN	_	Number=Sing	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	iNOS	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	transfection	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	assay	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	mouse	_	NOUN	_	Number=Sing	_	_	_	_
27	iNOS	_	NOUN	_	Number=Sing	_	_	_	_
28	promoter	_	VERB	_	Number=Sing	_	_	_	_
29	regions	_	NOUN	_	Number=Plur	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	response	_	NOUN	_	Number=Sing	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	LPS	_	NOUN	_	Number=Sing	_	_	_	_
34	+/-	_	SYM	_	_	_	_	_	_
35	IFN	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	gamma	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
41	mobility	_	NOUN	_	Number=Sing	_	_	_	_
42	shift	_	NOUN	_	Number=Sing	_	_	_	_
43	assays	_	NOUN	_	Number=Plur	_	_	_	_
44	of	_	ADP	_	_	_	_	_	_
45	kappa	_	NOUN	_	Number=Sing	_	_	_	_
46	B	_	NOUN	_	Number=Sing	_	_	_	_
47	response	_	NOUN	_	Number=Sing	_	_	_	_
48	elements	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Two	_	NUM	_	NumType=Card	_	_	_	_
2	explanations	_	NOUN	_	Number=Plur	_	_	_	_
3	for	_	ADP	_	_	_	_	_	_
4	hyporesponsiveness	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	human	_	ADJ	_	Degree=Pos	_	_	_	_
8	iNOS	_	NOUN	_	Number=Sing	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	LPS	_	NOUN	_	Number=Sing	_	_	_	_
12	+/-	_	SYM	_	_	_	_	_	_
13	IFN	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	gamma	_	NOUN	_	Number=Sing	_	_	_	_
16	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	:	_	PUNCT	_	_	_	_	_	_
19	(	_	PUNCT	_	_	_	_	_	_
20	1	_	X	_	_	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
23	inactivating	_	VERB	_	VerbForm=Ger	_	_	_	_
24	nucleotide	_	ADJ	_	Degree=Pos	_	_	_	_
25	substitutions	_	NOUN	_	Number=Plur	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	human	_	ADJ	_	Degree=Pos	_	_	_	_
29	counterpart	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
33	element	_	NOUN	_	Number=Sing	_	_	_	_
34	that	_	PRON	_	PronType=Rel	_	_	_	_
35	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
36	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
37	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	to	_	PART	_	_	_	_	_	_
39	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
40	LPS	_	NOUN	_	Number=Sing	_	_	_	_
41	/	_	PUNCT	_	_	_	_	_	_
42	IFN	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	gamma	_	NOUN	_	Number=Sing	_	_	_	_
45	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
46	expression	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
49	mouse	_	NOUN	_	Number=Sing	_	_	_	_
50	iNOS	_	PROPN	_	Degree=Pos	_	_	_	_
51	gene	_	NOUN	_	Number=Sing	_	_	_	_
52	;	_	PUNCT	_	_	_	_	_	_
53	and	_	CCONJ	_	_	_	_	_	_
54	(	_	PUNCT	_	_	_	_	_	_
55	2	_	X	_	_	_	_	_	_
56	)	_	PUNCT	_	_	_	_	_	_
57	and	_	CCONJ	_	_	_	_	_	_
58	absence	_	NOUN	_	Number=Sing	_	_	_	_
59	of	_	ADP	_	_	_	_	_	_
60	one	_	NUM	_	NumType=Card	_	_	_	_
61	or	_	CCONJ	_	_	_	_	_	_
62	more	_	ADJ	_	Degree=Cmp	_	_	_	_
63	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
64	factors	_	NOUN	_	Number=Plur	_	_	_	_
65	in	_	ADP	_	_	_	_	_	_
66	human	_	ADJ	_	Degree=Pos	_	_	_	_
67	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
68	(	_	PUNCT	_	_	_	_	_	_
69	e.g.	_	X	_	_	_	_	_	_
70	,	_	PUNCT	_	_	_	_	_	_
71	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
72	LPS	_	NOUN	_	Number=Sing	_	_	_	_
73	-	_	PUNCT	_	_	_	_	_	_
74	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
75	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
76	factor	_	NOUN	_	Number=Sing	_	_	_	_
77	-	_	PUNCT	_	_	_	_	_	_
78	kappa	_	NOUN	_	Number=Sing	_	_	_	_
79	B	_	NOUN	_	Number=Sing	_	_	_	_
80	/	_	PUNCT	_	_	_	_	_	_
81	Rel	_	NOUN	_	Number=Sing	_	_	_	_
82	complex	_	NOUN	_	Number=Sing	_	_	_	_
83	)	_	PUNCT	_	_	_	_	_	_
84	,	_	PUNCT	_	_	_	_	_	_
85	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
86	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
87	(	_	PUNCT	_	_	_	_	_	_
88	are	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
89	)	_	PUNCT	_	_	_	_	_	_
90	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
91	for	_	ADP	_	_	_	_	_	_
92	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
93	expression	_	NOUN	_	Number=Sing	_	_	_	_
94	of	_	ADP	_	_	_	_	_	_
95	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
96	gene	_	NOUN	_	Number=Sing	_	_	_	_
97	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	importance	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	resolution	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
7	controversy	_	NOUN	_	Number=Sing	_	_	_	_
8	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	future	_	ADJ	_	Degree=Pos	_	_	_	_
11	research	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
14	area	_	NOUN	_	Number=Sing	_	_	_	_
15	should	_	AUX	_	VerbForm=Fin	_	_	_	_
16	be	_	AUX	_	VerbForm=Inf	_	_	_	_
17	directed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	toward	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	understanding	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	alternative	_	ADJ	_	Degree=Pos	_	_	_	_
23	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	can	_	AUX	_	VerbForm=Fin	_	_	_	_
26	result	_	VERB	_	VerbForm=Inf	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	successful	_	ADJ	_	Degree=Pos	_	_	_	_
30	production	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	NO	_	INTJ	_	_	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013088	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	SRC	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	related	_	ADJ	_	Degree=Pos	_	_	_	_
4	proto	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	transcription	_	NOUN	_	Number=Sing	_	_	_	_
9	factors	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	primary	_	ADJ	_	Degree=Pos	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	modulation	_	NOUN	_	Number=Sing	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
19	A	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	FK506	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	lymphokines	_	NOUN	_	Number=Plur	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin-2	_	PROPN	_	Number=Sing	_	_	_	_
2	(	_	PUNCT	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	X	_	_	_	_	_	_
6	)	_	PUNCT	_	_	_	_	_	_
7	gene	_	NOUN	_	Number=Sing	_	_	_	_
8	expression	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	transcriptionally	_	ADV	_	_	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	cooperative	_	ADJ	_	Degree=Pos	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	trans	_	NOUN	_	Number=Plur	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	activating	_	NOUN	_	VerbForm=Ger	_	_	_	_
21	factors	_	NOUN	_	Number=Plur	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	2	_	NUM	_	NumType=Card	_	_	_	_
29	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Cyclosporin	_	PROPN	_	Number=Sing	_	_	_	_
2	A	_	PROPN	_	Number=Sing	_	_	_	_
3	(	_	PUNCT	_	_	_	_	_	_
4	CsA	_	PROPN	_	Number=Sing	_	_	_	_
5	)	_	PUNCT	_	_	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	FK506	_	PROPN	_	Number=Sing	_	_	_	_
8	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	production	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	2	_	NUM	_	NumType=Card	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
18	at	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	level	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	gene	_	NOUN	_	Number=Sing	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	member	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	src	_	NOUN	_	Degree=Pos	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	family	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	protein	_	NOUN	_	Number=Sing	_	_	_	_
14	tyrosine	_	NOUN	_	Number=Sing	_	_	_	_
15	kinase	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	p56lck	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
21	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	2	_	NUM	_	NumType=Card	_	_	_	_
26	production	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	CsA	_	PROPN	_	Number=Sing	_	_	_	_
2	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
3	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	not	_	ADV	_	_	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	inhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
7	lck	_	ADJ	_	Degree=Pos	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	expression	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	nor	_	CCONJ	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	activity	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	lck	_	NOUN	_	Number=Sing	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	product	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	CsA	_	PROPN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	FK506	_	PROPN	_	Number=Sing	_	_	_	_
6	inhibit	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	appearance	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	DNA	_	NOUN	_	Number=Sing	_	_	_	_
11	binding	_	VERB	_	Number=Sing	_	_	_	_
12	activity	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	bind	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	AT	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	AP	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	sites	_	NOUN	_	Number=Plur	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	IL	_	PROPN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	2	_	NUM	_	NumType=Card	_	_	_	_
32	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	induction	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	AT	_	ADP	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	AP	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	same	_	ADJ	_	Degree=Pos	_	_	_	_
17	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
18	that	_	PRON	_	PronType=Rel	_	_	_	_
19	stimulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	IL	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
26	results	_	NOUN	_	Number=Plur	_	_	_	_
27	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	immunosuppressant	_	ADJ	_	Degree=Pos	_	_	_	_
31	action	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	CsA	_	PROPN	_	Number=Sing	_	_	_	_
34	and	_	CCONJ	_	_	_	_	_	_
35	FK506	_	PROPN	_	Number=Sing	_	_	_	_
36	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	exerted	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	at	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	level	_	NOUN	_	Number=Sing	_	_	_	_
41	of	_	ADP	_	_	_	_	_	_
42	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
43	trans	_	NOUN	_	Number=Plur	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	activating	_	NOUN	_	VerbForm=Ger	_	_	_	_
46	factors	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013089	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	during	_	ADP	_	_	_	_	_	_
4	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
5	development	_	NOUN	_	Number=Sing	_	_	_	_
6	:	_	PUNCT	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	alpha	_	NOUN	_	Number=Sing	_	_	_	_
9	TCR	_	NOUN	_	Number=Sing	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	as	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
14	model	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	during	_	ADP	_	_	_	_	_	_
7	lymphocyte	_	NOUN	_	Number=Sing	_	_	_	_
8	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
11	complex	_	ADJ	_	Degree=Pos	_	_	_	_
12	process	_	NOUN	_	Number=Sing	_	_	_	_
13	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
14	interactions	_	NOUN	_	Number=Plur	_	_	_	_
15	between	_	ADP	_	_	_	_	_	_
16	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
17	positive	_	ADJ	_	Degree=Pos	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	negative	_	ADJ	_	Degree=Pos	_	_	_	_
20	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
21	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	elements	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	article	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
6	regulation	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	archetypal	_	ADJ	_	Degree=Pos	_	_	_	_
10	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	specific	_	ADJ	_	Degree=Pos	_	_	_	_
13	gene	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	TCR	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	discussed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Major	_	ADJ	_	Degree=Pos	_	_	_	_
2	recent	_	ADJ	_	Degree=Pos	_	_	_	_
3	developments	_	NOUN	_	Number=Plur	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	including	_	VERB	_	VerbForm=Ger	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	identification	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	novel	_	NOUN	_	Number=Sing	_	_	_	_
10	families	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	that	_	PRON	_	PronType=Rel	_	_	_	_
15	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
16	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
17	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	during	_	ADP	_	_	_	_	_	_
20	thymocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	ontogeny	_	NOUN	_	Number=Sing	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	described	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013093	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	GM	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	CSF	_	PROPN	_	Number=Sing	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	core	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	binding	_	NOUN	_	Number=Sing	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	GM	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	CSF	_	NOUN	_	Number=Sing	_	_	_	_
4	gene	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	T	_	PROPN	_	Number=Sing	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	to	_	PART	_	_	_	_	_	_
12	involve	_	VERB	_	VerbForm=Inf	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factors	_	NOUN	_	Number=Plur	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	AP	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	GM	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	CSF	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
13	also	_	ADV	_	_	_	_	_	_
14	encompass	_	VERB	_	VerbForm=Inf	_	_	_	_
15	binding	_	VERB	_	VerbForm=Ger	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	core	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	factor	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	CBF	_	PROPN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Significantly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	CBF	_	NOUN	_	Number=Sing	_	_	_	_
5	sites	_	NOUN	_	Number=Plur	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	each	_	DET	_	_	_	_	_	_
9	case	_	NOUN	_	Number=Sing	_	_	_	_
10	contained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	within	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	minimum	_	ADJ	_	Degree=Pos	_	_	_	_
14	essential	_	ADJ	_	Degree=Pos	_	_	_	_
15	core	_	NOUN	_	Number=Sing	_	_	_	_
16	regions	_	NOUN	_	Number=Plur	_	_	_	_
17	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	core	_	NOUN	_	Number=Sing	_	_	_	_
5	regions	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	enhancer	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	each	_	DET	_	_	_	_	_	_
12	encompass	_	NOUN	_	Number=Sing	_	_	_	_
13	closely	_	ADV	_	_	_	_	_	_
14	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	sites	_	NOUN	_	Number=Plur	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	CBF	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	AP	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	NFATp	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GM	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	CSF	_	PROPN	_	Number=Sing	_	_	_	_
5	promoter	_	NOUN	_	Number=Sing	_	_	_	_
6	CBF	_	PROPN	_	Number=Sing	_	_	_	_
7	site	_	NOUN	_	Number=Sing	_	_	_	_
8	TGTGGTCA	_	PROPN	_	Number=Sing	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	51	_	NUM	_	NumType=Card	_	_	_	_
12	bp	_	NOUN	_	Number=Sing	_	_	_	_
13	upstream	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	start	_	NOUN	_	Number=Sing	_	_	_	_
18	site	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	also	_	ADV	_	_	_	_	_	_
21	overlaps	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	YY	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	binding	_	NOUN	_	Number=Sing	_	_	_	_
27	site	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	2	_	NUM	_	NumType=Card	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	bp	_	NOUN	_	Number=Sing	_	_	_	_
5	mutation	_	NOUN	_	Number=Sing	_	_	_	_
6	within	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	CBF	_	PROPN	_	Number=Sing	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	resulted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	2	_	NUM	_	NumType=Card	_	_	_	_
14	-	_	SYM	_	_	_	_	_	_
15	3	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	fold	_	NOUN	_	Number=Sing	_	_	_	_
18	decrease	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	activities	_	NOUN	_	Number=Plur	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	both	_	CCONJ	_	_	_	_	_	_
24	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	69	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	bp	_	NOUN	_	Number=Sing	_	_	_	_
28	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
29	promoter	_	NOUN	_	Number=Sing	_	_	_	_
30	fragment	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	627	_	NUM	_	NumType=Card	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	bp	_	NOUN	_	Number=Sing	_	_	_	_
36	full	_	ADJ	_	Degree=Pos	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	length	_	NOUN	_	Number=Sing	_	_	_	_
39	promoter	_	NOUN	_	Number=Sing	_	_	_	_
40	fragment	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Stepwise	_	ADJ	_	Degree=Pos	_	_	_	_
2	deletions	_	NOUN	_	Number=Plur	_	_	_	_
3	into	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	also	_	ADV	_	_	_	_	_	_
8	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	CBF	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	but	_	CCONJ	_	_	_	_	_	_
15	not	_	ADV	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	YY	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	efficient	_	ADJ	_	Degree=Pos	_	_	_	_
26	induction	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	AML1	_	PROPN	_	Number=Sing	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	CBF	_	NOUN	_	Number=Sing	_	_	_	_
5	beta	_	NOUN	_	Number=Sing	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	encode	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	CBF	_	PROPN	_	Number=Sing	_	_	_	_
10	each	_	DET	_	_	_	_	_	_
11	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	ability	_	NOUN	_	Number=Sing	_	_	_	_
14	to	_	PART	_	_	_	_	_	_
15	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	growth	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
23	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	as	_	ADP	_	_	_	_	_	_
25	proto	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	oncogenes	_	NOUN	_	Number=Plur	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	acute	_	ADJ	_	Degree=Pos	_	_	_	_
30	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
31	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	adds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	GM	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	CSF	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	growing	_	VERB	_	VerbForm=Ger	_	_	_	_
10	list	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	receptors	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	PRON	_	PronType=Rel	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	by	_	ADP	_	_	_	_	_	_
19	CBF	_	PROPN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	which	_	PRON	_	PronType=Int	_	_	_	_
22	control	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	growth	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	activation	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	hemopoietic	_	ADJ	_	Degree=Pos	_	_	_	_
32	cells	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	GM	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	CSF	_	PROPN	_	Number=Sing	_	_	_	_
5	locus	_	NOUN	_	Number=Sing	_	_	_	_
6	may	_	AUX	_	VerbForm=Fin	_	_	_	_
7	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
8	one	_	NUM	_	NumType=Card	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	several	_	ADJ	_	Degree=Pos	_	_	_	_
11	target	_	NOUN	_	Number=Sing	_	_	_	_
12	genes	_	NOUN	_	Number=Plur	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	dysregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	acute	_	ADJ	_	Degree=Pos	_	_	_	_
18	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
19	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013094	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	Tat	_	PROPN	_	Number=Sing	_	_	_	_
5	potentiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	TNF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
16	by	_	SCONJ	_	_	_	_	_	_
17	altering	_	VERB	_	VerbForm=Ger	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
20	redox	_	NOUN	_	Number=Sing	_	_	_	_
21	state	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	study	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
7	virus	_	NOUN	_	Number=Sing	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	1	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	HIV	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	X	_	_	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	Tat	_	NOUN	_	Number=Sing	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	amplifies	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	tumor	_	NOUN	_	Number=Sing	_	_	_	_
22	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	TNF	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
30	that	_	PRON	_	PronType=Rel	_	_	_	_
31	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	HIV	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	1	_	NUM	_	NumType=Card	_	_	_	_
35	replication	_	NOUN	_	Number=Sing	_	_	_	_
36	through	_	ADP	_	_	_	_	_	_
37	activation	_	NOUN	_	Number=Sing	_	_	_	_
38	of	_	ADP	_	_	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappa	_	NOUN	_	Number=Sing	_	_	_	_
42	B.	_	PROPN	_	Number=Sing	_	_	_	_
43	In	_	ADP	_	_	_	_	_	_
44	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
45	cells	_	NOUN	_	Number=Plur	_	_	_	_
46	stably	_	ADV	_	_	_	_	_	_
47	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
48	with	_	ADP	_	_	_	_	_	_
49	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
50	HIV	_	PROPN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	1	_	NUM	_	NumType=Card	_	_	_	_
53	tat	_	NOUN	_	Degree=Pos	_	_	_	_
54	gene	_	NOUN	_	Number=Sing	_	_	_	_
55	(	_	PUNCT	_	_	_	_	_	_
56	HeLa	_	NOUN	_	Number=Sing	_	_	_	_
57	-	_	PUNCT	_	_	_	_	_	_
58	tat	_	NOUN	_	Number=Sing	_	_	_	_
59	cells	_	NOUN	_	Number=Plur	_	_	_	_
60	)	_	PUNCT	_	_	_	_	_	_
61	,	_	PUNCT	_	_	_	_	_	_
62	expression	_	NOUN	_	Number=Sing	_	_	_	_
63	of	_	ADP	_	_	_	_	_	_
64	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
65	Tat	_	PROPN	_	Number=Sing	_	_	_	_
66	protein	_	NOUN	_	Number=Sing	_	_	_	_
67	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
68	both	_	CCONJ	_	_	_	_	_	_
69	TNF	_	PROPN	_	Number=Sing	_	_	_	_
70	-	_	PUNCT	_	_	_	_	_	_
71	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
72	activation	_	NOUN	_	Number=Sing	_	_	_	_
73	of	_	ADP	_	_	_	_	_	_
74	NF	_	PROPN	_	Number=Sing	_	_	_	_
75	-	_	PUNCT	_	_	_	_	_	_
76	kappa	_	NOUN	_	Number=Sing	_	_	_	_
77	B	_	NOUN	_	Number=Sing	_	_	_	_
78	and	_	CCONJ	_	_	_	_	_	_
79	TNF	_	NOUN	_	Number=Sing	_	_	_	_
80	-	_	PUNCT	_	_	_	_	_	_
81	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
82	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
83	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	similar	_	ADJ	_	Degree=Pos	_	_	_	_
3	potentiation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	TNF	_	PROPN	_	Number=Sing	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	soluble	_	ADJ	_	Degree=Pos	_	_	_	_
19	Tat	_	NOUN	_	Number=Sing	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
12	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
15	formation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	reactive	_	ADJ	_	Degree=Pos	_	_	_	_
18	oxygen	_	NOUN	_	Number=Sing	_	_	_	_
19	intermediates	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Tat	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	mediated	_	VERB	_	Degree=Pos	_	_	_	_
6	effects	_	NOUN	_	Number=Plur	_	_	_	_
7	on	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
10	redox	_	NOUN	_	Number=Sing	_	_	_	_
11	state	_	NOUN	_	Number=Sing	_	_	_	_
12	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	analyzed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	both	_	CCONJ	_	_	_	_	_	_
3	T	_	PROPN	_	Number=Sing	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	HIV	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	Tat	_	NOUN	_	Number=Sing	_	_	_	_
12	suppressed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	expression	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	Mn	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
19	superoxide	_	NOUN	_	Number=Sing	_	_	_	_
20	dismutase	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	Mn	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	SOD	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
28	mitochondrial	_	ADJ	_	Degree=Pos	_	_	_	_
29	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
30	that	_	PRON	_	PronType=Rel	_	_	_	_
31	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
32	part	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
36	defense	_	NOUN	_	Number=Sing	_	_	_	_
37	system	_	NOUN	_	Number=Sing	_	_	_	_
38	against	_	ADP	_	_	_	_	_	_
39	oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
40	stress	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	Mn-SOD	_	PROPN	_	Degree=Pos	_	_	_	_
4	RNA	_	PROPN	_	Number=Sing	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	levels	_	NOUN	_	Number=Plur	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	activity	_	NOUN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	markedly	_	ADV	_	_	_	_	_	_
11	reduced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	presence	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	Tat	_	PROPN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	Mn	_	ADP	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	SOD	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
15	lower	_	ADJ	_	Degree=Cmp	_	_	_	_
16	ratio	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	:	_	PUNCT	_	_	_	_	_	_
20	oxidized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	truncated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	Tat	_	NOUN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	Tat1	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	SYM	_	_	_	_	_	_
8	72	_	NUM	_	NumType=Card	_	_	_	_
9	)	_	PUNCT	_	_	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	transactivate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	HIV	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	1	_	NUM	_	NumType=Card	_	_	_	_
18	long	_	ADJ	_	Degree=Pos	_	_	_	_
19	terminal	_	NOUN	_	Number=Sing	_	_	_	_
20	repeat	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	LTR	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	no	_	ADV	_	_	_	_	_	_
26	longer	_	ADV	_	Degree=Cmp	_	_	_	_
27	affected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	Mn	_	ADP	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	SOD	_	NOUN	_	Number=Sing	_	_	_	_
31	expression	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
35	redox	_	NOUN	_	Number=Sing	_	_	_	_
36	state	_	NOUN	_	Number=Sing	_	_	_	_
37	or	_	CCONJ	_	_	_	_	_	_
38	TNF	_	PROPN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
41	cytotoxicity	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	experiments	_	NOUN	_	Number=Plur	_	_	_	_
5	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	C	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	terminal	_	NOUN	_	Number=Sing	_	_	_	_
11	region	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	HIV	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	1	_	NUM	_	NumType=Card	_	_	_	_
16	Tat	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	to	_	PART	_	_	_	_	_	_
20	suppress	_	VERB	_	VerbForm=Inf	_	_	_	_
21	Mn	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	SOD	_	NOUN	_	Number=Sing	_	_	_	_
24	expression	_	NOUN	_	Number=Sing	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	to	_	PART	_	_	_	_	_	_
27	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
28	pro-oxidative	_	ADJ	_	Degree=Pos	_	_	_	_
29	conditions	_	NOUN	_	Number=Plur	_	_	_	_
30	reflected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	by	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	drop	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	glutathione	_	NOUN	_	Number=Sing	_	_	_	_
37	(	_	PUNCT	_	_	_	_	_	_
38	GSH	_	NOUN	_	Number=Sing	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	and	_	CCONJ	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	GSH	_	NOUN	_	Number=Sing	_	_	_	_
43	:	_	PUNCT	_	_	_	_	_	_
44	oxidized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	GSH	_	NOUN	_	Number=Sing	_	_	_	_
46	(	_	PUNCT	_	_	_	_	_	_
47	GSSG	_	NOUN	_	Number=Sing	_	_	_	_
48	)	_	PUNCT	_	_	_	_	_	_
49	ratio	_	NOUN	_	Number=Sing	_	_	_	_
50	.	_	PUNCT	_	_	_	_	_	_

1	(	_	PUNCT	_	_	_	_	_	_
2	ABSTRACT	_	NOUN	_	Number=Sing	_	_	_	_
3	TRUNCATED	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	AT	_	ADP	_	_	_	_	_	_
5	250	_	NUM	_	NumType=Card	_	_	_	_
6	WORDS	_	NOUN	_	Number=Plur	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	Document	_	NOUN	_	Number=Sing	_	_	_	_
9	0030013096	_	NUM	_	NumType=Card	_	_	_	_
10	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	E2F	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	like	_	ADP	_	Degree=Pos	_	_	_	_
9	DNA	_	PROPN	_	Number=Sing	_	_	_	_
10	repair	_	NOUN	_	Number=Sing	_	_	_	_
11	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	uracil	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	DNA	_	PROPN	_	Number=Sing	_	_	_	_
16	glycosylase	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
19	evidence	_	NOUN	_	Number=Sing	_	_	_	_
20	for	_	ADP	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	autoregulatory	_	ADJ	_	Degree=Pos	_	_	_	_
23	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	transcription	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	cell	_	NOUN	_	Number=Sing	_	_	_	_
3	cycle	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	factor	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	E2F	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	like	_	ADJ	_	Degree=Pos	_	_	_	_
18	species	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	DNA	_	PROPN	_	Number=Sing	_	_	_	_
22	repair	_	NOUN	_	Number=Sing	_	_	_	_
23	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
24	uracil	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	DNA	_	PROPN	_	Number=Sing	_	_	_	_
27	glycosylase	_	NOUN	_	Number=Sing	_	_	_	_
28	(	_	PUNCT	_	_	_	_	_	_
29	UDG	_	NOUN	_	Number=Sing	_	_	_	_
30	)	_	PUNCT	_	_	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	human	_	ADJ	_	Degree=Pos	_	_	_	_
34	osteosarcoma	_	NOUN	_	Number=Sing	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	Saos	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	2	_	NUM	_	NumType=Card	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	cells	_	NOUN	_	Number=Plur	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	through	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	deletion	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	UDG	_	NOUN	_	Number=Sing	_	_	_	_
11	promoter	_	NOUN	_	Number=Sing	_	_	_	_
12	sequences	_	NOUN	_	Number=Plur	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
15	expression	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	E2F	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	1	_	NUM	_	NumType=Card	_	_	_	_
20	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	UDG	_	PROPN	_	Number=Sing	_	_	_	_
23	promoter	_	NOUN	_	Number=Sing	_	_	_	_
24	through	_	ADP	_	_	_	_	_	_
25	several	_	ADJ	_	Degree=Pos	_	_	_	_
26	E2F	_	NOUN	_	Number=Sing	_	_	_	_
27	sites	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	major	_	ADJ	_	Degree=Pos	_	_	_	_
3	putative	_	ADJ	_	Degree=Pos	_	_	_	_
4	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
5	site	_	NOUN	_	Number=Sing	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	E2F	_	PROPN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
13	exon	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	serves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	as	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	target	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	E2F	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1/DP1	_	NUM	_	Number=Sing	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vitro	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	evidence	_	NOUN	_	Number=Sing	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	functional	_	ADJ	_	Degree=Pos	_	_	_	_
8	relationship	_	NOUN	_	Number=Sing	_	_	_	_
9	between	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	cyclin	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	like	_	ADJ	_	_	_	_	_	_
14	UDG	_	NOUN	_	Number=Sing	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	product	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	E2F	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	High	_	ADJ	_	Degree=Pos	_	_	_	_
2	levels	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	UDG	_	PROPN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	transient	_	ADJ	_	Degree=Pos	_	_	_	_
9	transfection	_	NOUN	_	Number=Sing	_	_	_	_
10	assay	_	NOUN	_	Number=Sing	_	_	_	_
11	result	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	down	_	ADJ	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
19	activity	_	NOUN	_	Number=Sing	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	elements	_	NOUN	_	Number=Plur	_	_	_	_
22	specific	_	ADJ	_	Degree=Pos	_	_	_	_
23	for	_	ADP	_	_	_	_	_	_
24	E2F	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Overexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	UDG	_	PROPN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	Saos	_	PROPN	_	Number=Sing	_	_	_	_
6	2	_	NUM	_	NumType=Card	_	_	_	_
7	cells	_	NOUN	_	Number=Plur	_	_	_	_
8	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
9	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	delay	_	VERB	_	VerbForm=Inf	_	_	_	_
12	growth	_	NOUN	_	Number=Sing	_	_	_	_
13	late	_	ADV	_	Degree=Pos	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	G1	_	PROPN	_	Number=Sing	_	_	_	_
16	phase	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	transiently	_	ADV	_	_	_	_	_	_
19	arrest	_	VERB	_	VerbForm=Inf	_	_	_	_
20	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	from	_	SCONJ	_	_	_	_	_	_
23	progressing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	into	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	S	_	NOUN	_	Number=Sing	_	_	_	_
27	phase	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	hypothetical	_	ADJ	_	Degree=Pos	_	_	_	_
3	model	_	NOUN	_	Number=Sing	_	_	_	_
4	integrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	one	_	NUM	_	NumType=Card	_	_	_	_
6	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	DNA	_	NOUN	_	Number=Sing	_	_	_	_
9	repair	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	cycle	_	NOUN	_	Number=Sing	_	_	_	_
14	control	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	likely	_	ADV	_	_	_	_	_	_
20	through	_	ADP	_	_	_	_	_	_
21	E2F	_	PROPN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	This	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
2	implicates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	E2F	_	PROPN	_	Number=Sing	_	_	_	_
4	as	_	ADP	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	multifunctional	_	ADJ	_	Degree=Pos	_	_	_	_
7	target	_	NOUN	_	Number=Sing	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	proteins	_	NOUN	_	Number=Plur	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	enzymes	_	NOUN	_	Number=Plur	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	possibly	_	ADV	_	_	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	responsive	_	ADJ	_	Degree=Pos	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	DNA	_	NOUN	_	Number=Sing	_	_	_	_
18	damage	_	NOUN	_	Number=Sing	_	_	_	_
19	through	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	negative	_	ADJ	_	Degree=Pos	_	_	_	_
22	effect	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	UDG	_	NOUN	_	Number=Sing	_	_	_	_
25	on	_	ADP	_	_	_	_	_	_
26	E2F	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
29	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013098	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	novel	_	NOUN	_	Number=Sing	_	_	_	_
3	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
4	trans	_	NOUN	_	Number=Plur	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	activator	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
11	ester	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
14	element	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	2	_	NUM	_	NumType=Card	_	_	_	_
20	promoter	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
3	2	_	NUM	_	NumType=Card	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	2	_	NUM	_	_	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	promoter	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	recognized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	several	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
22	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
23	regulators	_	NOUN	_	Number=Plur	_	_	_	_
24	that	_	PRON	_	PronType=Rel	_	_	_	_
25	integrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	information	_	NOUN	_	Number=Sing	_	_	_	_
27	transmitted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
28	by	_	ADP	_	_	_	_	_	_
29	various	_	ADJ	_	Degree=Pos	_	_	_	_
30	signaling	_	NOUN	_	Number=Sing	_	_	_	_
31	systems	_	NOUN	_	Number=Plur	_	_	_	_
32	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	IL	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	production	_	NOUN	_	Number=Sing	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
40	activation	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	combination	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	transfection	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	DNA	_	PROPN	_	Number=Sing	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vitro	_	NOUN	_	Number=Sing	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	methods	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
19	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	discovered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	novel	_	NOUN	_	Number=Sing	_	_	_	_
23	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	specific	_	ADJ	_	Degree=Pos	_	_	_	_
26	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
27	activator	_	NOUN	_	Number=Sing	_	_	_	_
28	TCF	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	1	_	NUM	_	NumType=Card	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	T-Cell	_	NOUN	_	Number=Sing	_	_	_	_
34	Factor	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	1	_	NUM	_	NumType=Card	_	_	_	_
37	)	_	PUNCT	_	_	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	which	_	PRON	_	PronType=Rel	_	_	_	_
40	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
42	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	specific	_	ADJ	_	Degree=Pos	_	_	_	_
45	response	_	NOUN	_	Number=Sing	_	_	_	_
46	element	_	NOUN	_	Number=Sing	_	_	_	_
47	(	_	PUNCT	_	_	_	_	_	_
48	TCE	_	NOUN	_	Number=Sing	_	_	_	_
49	)	_	PUNCT	_	_	_	_	_	_
50	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
51	within	_	ADP	_	_	_	_	_	_
52	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
53	IL	_	PROPN	_	Number=Sing	_	_	_	_
54	-	_	PUNCT	_	_	_	_	_	_
55	2	_	NUM	_	NumType=Card	_	_	_	_
56	promoter	_	NOUN	_	Number=Sing	_	_	_	_
57	.	_	PUNCT	_	_	_	_	_	_

1	Although	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	TCE	_	PROPN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	similar	_	ADJ	_	Degree=Pos	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	sequence	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	consensus	_	NOUN	_	Number=Sing	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	site	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	several	_	ADJ	_	Degree=Pos	_	_	_	_
17	criteria	_	NOUN	_	Number=Plur	_	_	_	_
18	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
19	that	_	SCONJ	_	_	_	_	_	_
20	TCF	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	kappa	_	PROPN	_	Number=Sing	_	_	_	_
28	B.	_	PROPN	_	Number=Sing	_	_	_	_
29	However	_	ADV	_	_	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	like	_	ADP	_	_	_	_	_	_
32	NF	_	PROPN	_	Number=Sing	_	_	_	_
33	kappa	_	PROPN	_	Number=Sing	_	_	_	_
34	B	_	PROPN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	TCF	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	activity	_	NOUN	_	Number=Sing	_	_	_	_
40	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
41	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
42	by	_	ADP	_	_	_	_	_	_
43	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
44	esters	_	NOUN	_	Number=Plur	_	_	_	_
45	and	_	CCONJ	_	_	_	_	_	_
46	other	_	ADJ	_	Degree=Pos	_	_	_	_
47	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
48	activators	_	NOUN	_	Number=Plur	_	_	_	_
49	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013109	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Isolation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
4	clones	_	NOUN	_	Number=Plur	_	_	_	_
5	for	_	ADP	_	_	_	_	_	_
6	42	_	NUM	_	NumType=Card	_	_	_	_
7	different	_	ADJ	_	Degree=Pos	_	_	_	_
8	Kruppel	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	related	_	ADJ	_	Degree=Pos	_	_	_	_
11	zinc	_	NOUN	_	Number=Sing	_	_	_	_
12	finger	_	NOUN	_	Number=Sing	_	_	_	_
13	proteins	_	NOUN	_	Number=Plur	_	_	_	_
14	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	monoblast	_	NOUN	_	Number=Sing	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	line	_	NOUN	_	Number=Sing	_	_	_	_
21	U	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	937	_	NUM	_	NumType=Card	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	study	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	complexity	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	structural	_	ADJ	_	Degree=Pos	_	_	_	_
7	characteristics	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	zinc	_	NOUN	_	Number=Sing	_	_	_	_
10	finger	_	NOUN	_	Number=Sing	_	_	_	_
11	proteins	_	NOUN	_	Number=Plur	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	during	_	ADP	_	_	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	hematopoiesis	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	isolate	_	VERB	_	VerbForm=Inf	_	_	_	_
19	novel	_	NOUN	_	Number=Sing	_	_	_	_
20	regulators	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	blood	_	NOUN	_	Number=Sing	_	_	_	_
23	cell	_	NOUN	_	Number=Sing	_	_	_	_
24	development	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	degenerate	_	ADJ	_	Degree=Pos	_	_	_	_
28	oligonucleotide	_	ADJ	_	Number=Sing	_	_	_	_
29	probe	_	NOUN	_	Number=Sing	_	_	_	_
30	specific	_	ADJ	_	Degree=Pos	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	consensus	_	NOUN	_	Number=Sing	_	_	_	_
34	zinc	_	NOUN	_	Number=Sing	_	_	_	_
35	finger	_	NOUN	_	Number=Sing	_	_	_	_
36	peptide	_	NOUN	_	Number=Sing	_	_	_	_
37	domain	_	NOUN	_	Number=Sing	_	_	_	_
38	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
39	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
40	to	_	PART	_	_	_	_	_	_
41	isolate	_	VERB	_	VerbForm=Inf	_	_	_	_
42	63	_	NUM	_	NumType=Card	_	_	_	_
43	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
44	clones	_	NOUN	_	Number=Plur	_	_	_	_
45	for	_	ADP	_	_	_	_	_	_
46	Kruppel	_	PROPN	_	Number=Sing	_	_	_	_
47	-	_	PUNCT	_	_	_	_	_	_
48	related	_	ADJ	_	Degree=Pos	_	_	_	_
49	zinc	_	NOUN	_	Number=Sing	_	_	_	_
50	finger	_	NOUN	_	Number=Sing	_	_	_	_
51	genes	_	NOUN	_	Number=Plur	_	_	_	_
52	from	_	ADP	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	human	_	ADJ	_	Degree=Pos	_	_	_	_
55	monoblast	_	NOUN	_	Number=Sing	_	_	_	_
56	cell	_	NOUN	_	Number=Sing	_	_	_	_
57	line	_	NOUN	_	Number=Sing	_	_	_	_
58	U	_	NOUN	_	Number=Sing	_	_	_	_
59	-	_	SYM	_	_	_	_	_	_
60	937	_	NUM	_	NumType=Card	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	By	_	ADP	_	_	_	_	_	_
2	extensive	_	ADJ	_	Degree=Pos	_	_	_	_
3	nucleotide	_	NOUN	_	Degree=Pos	_	_	_	_
4	sequence	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
7	blot	_	NOUN	_	Number=Sing	_	_	_	_
8	analysis	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
11	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
12	clones	_	NOUN	_	Number=Plur	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	to	_	PART	_	_	_	_	_	_
16	originate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	from	_	ADP	_	_	_	_	_	_
18	approximately	_	ADV	_	_	_	_	_	_
19	42	_	NUM	_	NumType=Card	_	_	_	_
20	different	_	ADJ	_	Degree=Pos	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	HZF	_	PROPN	_	Number=Sing	_	_	_	_
24	1	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	42	_	NUM	_	NumType=Card	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	which	_	PRON	_	PronType=Rel	_	_	_	_
30	only	_	ADV	_	_	_	_	_	_
31	8	_	NUM	_	NumType=Card	_	_	_	_
32	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
33	previously	_	ADV	_	_	_	_	_	_
34	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
35	described	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Northern	_	ADJ	_	Degree=Pos	_	_	_	_
2	blot	_	PROPN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	majority	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
10	genes	_	NOUN	_	Number=Plur	_	_	_	_
11	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
12	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	at	_	ADP	_	_	_	_	_	_
14	comparable	_	ADJ	_	Degree=Pos	_	_	_	_
15	levels	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	U-937	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	large	_	ADJ	_	Degree=Pos	_	_	_	_
3	number	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	individual	_	ADJ	_	Degree=Pos	_	_	_	_
6	genes	_	NOUN	_	Number=Plur	_	_	_	_
7	represented	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	among	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	63	_	NUM	_	NumType=Card	_	_	_	_
11	clones	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
14	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
15	non-cell	_	ADJ	_	Degree=Pos	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	type	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	specific	_	ADJ	_	Degree=Pos	_	_	_	_
20	expression	_	NOUN	_	Number=Sing	_	_	_	_
21	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	that	_	SCONJ	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	majority	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	Kruppel	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	related	_	ADJ	_	Degree=Pos	_	_	_	_
30	zinc	_	NOUN	_	Number=Sing	_	_	_	_
31	finger	_	NOUN	_	Number=Sing	_	_	_	_
32	genes	_	NOUN	_	Number=Plur	_	_	_	_
33	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	likely	_	ADV	_	Degree=Pos	_	_	_	_
35	to	_	PART	_	_	_	_	_	_
36	be	_	AUX	_	VerbForm=Inf	_	_	_	_
37	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	most	_	ADJ	_	_	_	_	_	_
40	human	_	ADJ	_	Degree=Pos	_	_	_	_
41	tissues	_	NOUN	_	Number=Plur	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	some	_	DET	_	_	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	genes	_	NOUN	_	Number=Plur	_	_	_	_
8	displayed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	pattern	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
15	that	_	SCONJ	_	_	_	_	_	_
16	they	_	PRON	_	Case=Nom|Number=Plur|Person=3|PronType=Prs	_	_	_	_
17	represent	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
18	potential	_	ADJ	_	Degree=Pos	_	_	_	_
19	regulators	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	monocyte	_	ADJ	_	Number=Sing	_	_	_	_
22	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Detailed	_	ADJ	_	Degree=Pos	_	_	_	_
2	structural	_	ADJ	_	Degree=Pos	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
7	12	_	NUM	_	NumType=Card	_	_	_	_
8	cDNAs	_	NOUN	_	Number=Plur	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	HZF	_	PROPN	_	Number=Sing	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	SYM	_	_	_	_	_	_
13	10	_	NUM	_	NumType=Card	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	partial	_	ADJ	_	Degree=Pos	_	_	_	_
18	characterization	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	HZF	_	PROPN	_	Number=Sing	_	_	_	_
21	11	_	NUM	_	NumType=Card	_	_	_	_
22	-	_	SYM	_	_	_	_	_	_
23	42	_	NUM	_	NumType=Card	_	_	_	_
24	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	common	_	ADJ	_	Degree=Pos	_	_	_	_
28	feature	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	Kruppel	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	related	_	ADJ	_	Degree=Pos	_	_	_	_
34	zinc	_	NOUN	_	Number=Sing	_	_	_	_
35	finger	_	NOUN	_	Number=Sing	_	_	_	_
36	proteins	_	NOUN	_	Number=Plur	_	_	_	_
37	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	presence	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	tandem	_	NOUN	_	Number=Sing	_	_	_	_
42	arrays	_	NOUN	_	Number=Plur	_	_	_	_
43	of	_	ADP	_	_	_	_	_	_
44	zinc	_	NOUN	_	Number=Sing	_	_	_	_
45	fingers	_	NOUN	_	Number=Plur	_	_	_	_
46	ranging	_	VERB	_	VerbForm=Ger	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	number	_	NOUN	_	Number=Sing	_	_	_	_
49	from	_	ADP	_	_	_	_	_	_
50	3	_	NUM	_	NumType=Card	_	_	_	_
51	to	_	ADP	_	_	_	_	_	_
52	over	_	ADV	_	_	_	_	_	_
53	20	_	NUM	_	NumType=Card	_	_	_	_
54	that	_	PRON	_	PronType=Rel	_	_	_	_
55	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
56	preferentially	_	ADV	_	_	_	_	_	_
57	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
58	in	_	ADP	_	_	_	_	_	_
59	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
60	carboxy	_	NOUN	_	Number=Sing	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	terminal	_	ADJ	_	Number=Sing	_	_	_	_
63	regions	_	NOUN	_	Number=Plur	_	_	_	_
64	of	_	ADP	_	_	_	_	_	_
65	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
66	proteins	_	NOUN	_	Number=Plur	_	_	_	_
67	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	several	_	ADJ	_	Degree=Pos	_	_	_	_
5	novel	_	NOUN	_	Number=Sing	_	_	_	_
6	KRAB	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	zinc	_	NOUN	_	Number=Sing	_	_	_	_
10	finger	_	NOUN	_	Number=Sing	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	novel	_	NOUN	_	Number=Sing	_	_	_	_
15	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	sequence	_	NOUN	_	Number=Sing	_	_	_	_
17	element	_	NOUN	_	Number=Sing	_	_	_	_
18	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	identified	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013110	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Contribution	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
9	binding	_	VERB	_	Number=Sing	_	_	_	_
10	motifs	_	NOUN	_	Number=Plur	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	replicative	_	ADJ	_	Degree=Pos	_	_	_	_
14	capacity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
18	virus	_	NOUN	_	Number=Sing	_	_	_	_
19	type	_	NOUN	_	Number=Sing	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	:	_	PUNCT	_	_	_	_	_	_
22	distinct	_	ADJ	_	Degree=Pos	_	_	_	_
23	patterns	_	NOUN	_	Number=Plur	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	viral	_	ADJ	_	Degree=Pos	_	_	_	_
26	growth	_	NOUN	_	Number=Sing	_	_	_	_
27	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
28	determined	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	by	_	ADP	_	_	_	_	_	_
30	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
31	types	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Starting	_	VERB	_	VerbForm=Ger	_	_	_	_
2	with	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	replication	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	incompetent	_	ADJ	_	Degree=Pos	_	_	_	_
7	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
8	clone	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	human	_	ADJ	_	Degree=Pos	_	_	_	_
11	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
12	virus	_	NOUN	_	Number=Sing	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
17	all	_	DET	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	Sp1	_	PROPN	_	Number=Sing	_	_	_	_
25	binding	_	NOUN	_	Number=Sing	_	_	_	_
26	sites	_	NOUN	_	Number=Plur	_	_	_	_
27	present	_	VERB	_	Degree=Pos	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	native	_	ADJ	_	Degree=Pos	_	_	_	_
31	long	_	ADJ	_	Degree=Pos	_	_	_	_
32	terminal	_	NOUN	_	Number=Sing	_	_	_	_
33	repeat	_	NOUN	_	Number=Sing	_	_	_	_
34	(	_	PUNCT	_	_	_	_	_	_
35	LTR	_	NOUN	_	Number=Sing	_	_	_	_
36	)	_	PUNCT	_	_	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	proviruses	_	NOUN	_	Number=Plur	_	_	_	_
39	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
40	reconstructed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
41	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
42	with	_	ADP	_	_	_	_	_	_
43	individual	_	NOUN	_	Number=Sing	_	_	_	_
44	or	_	CCONJ	_	_	_	_	_	_
45	combinations	_	NOUN	_	Number=Plur	_	_	_	_
46	of	_	ADP	_	_	_	_	_	_
47	NF	_	PROPN	_	Number=Sing	_	_	_	_
48	-	_	PUNCT	_	_	_	_	_	_
49	kappa	_	NOUN	_	Number=Sing	_	_	_	_
50	B	_	NOUN	_	Number=Sing	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
53	elements	_	NOUN	_	Number=Plur	_	_	_	_
54	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
55	generated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
56	and	_	CCONJ	_	_	_	_	_	_
57	evaluated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
58	for	_	ADP	_	_	_	_	_	_
59	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
60	capacity	_	NOUN	_	Number=Sing	_	_	_	_
61	to	_	PART	_	_	_	_	_	_
62	produce	_	VERB	_	VerbForm=Inf	_	_	_	_
63	virus	_	NOUN	_	Number=Sing	_	_	_	_
64	progeny	_	NOUN	_	Number=Sing	_	_	_	_
65	following	_	VERB	_	VerbForm=Ger	_	_	_	_
66	transfection	_	NOUN	_	Number=Sing	_	_	_	_
67	-	_	PUNCT	_	_	_	_	_	_
68	cocultivation	_	NOUN	_	Number=Sing	_	_	_	_
69	.	_	PUNCT	_	_	_	_	_	_

1	Virus	_	NOUN	_	Number=Sing	_	_	_	_
2	stocks	_	NOUN	_	Number=Plur	_	_	_	_
3	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	experiments	_	NOUN	_	Number=Plur	_	_	_	_
7	exhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	continuum	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	replicative	_	ADJ	_	Degree=Pos	_	_	_	_
12	capacities	_	NOUN	_	Number=Plur	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	different	_	ADJ	_	Degree=Pos	_	_	_	_
15	human	_	ADJ	_	Degree=Pos	_	_	_	_
16	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
17	types	_	NOUN	_	Number=Plur	_	_	_	_
18	depending	_	VERB	_	VerbForm=Ger	_	_	_	_
19	on	_	ADP	_	_	_	_	_	_
20	which	_	DET	_	PronType=Int	_	_	_	_
21	element	_	NOUN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	s	_	X	_	_	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
26	present	_	ADJ	_	Degree=Pos	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	LTR	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	For	_	ADP	_	_	_	_	_	_
2	example	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	experiments	_	NOUN	_	Number=Plur	_	_	_	_
6	involving	_	VERB	_	VerbForm=Ger	_	_	_	_
7	proviral	_	ADJ	_	Degree=Pos	_	_	_	_
8	clones	_	NOUN	_	Number=Plur	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	LTRs	_	NOUN	_	Number=Plur	_	_	_	_
11	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
12	one	_	NUM	_	NumType=Card	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	two	_	NUM	_	NumType=Card	_	_	_	_
15	NF	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	NOUN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	elements	_	NOUN	_	Number=Plur	_	_	_	_
20	(	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	no	_	DET	_	_	_	_	_	_
23	Sp1	_	NOUN	_	Number=Sing	_	_	_	_
24	binding	_	NOUN	_	Number=Sing	_	_	_	_
25	sites	_	NOUN	_	Number=Plur	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	hierarchy	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
32	permissivity	_	NOUN	_	Number=Sing	_	_	_	_
33	to	_	ADP	_	_	_	_	_	_
34	virus	_	NOUN	_	Number=Sing	_	_	_	_
35	replication	_	NOUN	_	Number=Sing	_	_	_	_
36	(	_	PUNCT	_	_	_	_	_	_
37	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
38	blood	_	NOUN	_	Number=Sing	_	_	_	_
39	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
40	=	_	PUNCT	_	_	_	_	_	_
41	MT4	_	PROPN	_	Number=Sing	_	_	_	_
42	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
43	than	_	ADP	_	_	_	_	_	_
44	H9	_	NUM	_	Number=Sing	_	_	_	_
45	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
46	than	_	ADP	_	_	_	_	_	_
47	CEM	_	PROPN	_	Number=Sing	_	_	_	_
48	greater	_	ADJ	_	Degree=Cmp	_	_	_	_
49	than	_	ADP	_	_	_	_	_	_
50	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
53	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
54	.	_	PUNCT	_	_	_	_	_	_

1	Of	_	ADP	_	_	_	_	_	_
2	note	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	emergence	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	LTR	_	PROPN	_	Number=Sing	_	_	_	_
12	revertants	_	NOUN	_	Number=Plur	_	_	_	_
13	which	_	PRON	_	PronType=Rel	_	_	_	_
14	involved	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	alteration	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	TATA	_	NOUN	_	Number=Sing	_	_	_	_
20	box	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
8	virus	_	NOUN	_	Number=Sing	_	_	_	_
9	type	_	NOUN	_	Number=Sing	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	LTR	_	NOUN	_	Number=Sing	_	_	_	_
12	possesses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	functional	_	ADJ	_	Degree=Pos	_	_	_	_
14	redundancy	_	NOUN	_	Number=Sing	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	ensures	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	virus	_	NOUN	_	Number=Sing	_	_	_	_
18	replication	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	different	_	ADJ	_	Degree=Pos	_	_	_	_
21	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
22	types	_	NOUN	_	Number=Plur	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	capable	_	ADJ	_	Degree=Pos	_	_	_	_
26	of	_	SCONJ	_	_	_	_	_	_
27	changing	_	VERB	_	VerbForm=Ger	_	_	_	_
28	depending	_	VERB	_	VerbForm=Ger	_	_	_	_
29	on	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	particular	_	ADJ	_	Degree=Pos	_	_	_	_
32	combination	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
35	factors	_	NOUN	_	Number=Plur	_	_	_	_
36	present	_	VERB	_	Degree=Pos	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013115	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Oxidant	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	regulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	expression	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	chronically	_	ADV	_	_	_	_	_	_
10	inflamed	_	VERB	_	Degree=Pos	_	_	_	_
11	intestine	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	becoming	_	VERB	_	Tense=Pres|VerbForm=Part	_	_	_	_
4	increasingly	_	ADV	_	_	_	_	_	_
5	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	chronic	_	ADJ	_	Number=Sing	_	_	_	_
9	gut	_	NOUN	_	Number=Sing	_	_	_	_
10	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
11	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	idiopathic	_	ADJ	_	Degree=Pos	_	_	_	_
15	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
16	bowel	_	NOUN	_	Number=Sing	_	_	_	_
17	diseases	_	NOUN	_	Number=Plur	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	e.g.	_	X	_	_	_	_	_	_
20	ulcerative	_	ADJ	_	Degree=Pos	_	_	_	_
21	colitis	_	NOUN	_	Number=Sing	_	_	_	_
22	,	_	PUNCT	_	_	_	_	_	_
23	Crohn	_	PROPN	_	Number=Sing	_	_	_	_
24	's	_	PART	_	_	_	_	_	_
25	disease	_	NOUN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
28	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
29	with	_	ADP	_	_	_	_	_	_
30	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
31	production	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	oxidants	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Oxidants	_	NOUN	_	Number=Plur	_	_	_	_
2	such	_	ADJ	_	Degree=Pos	_	_	_	_
3	as	_	SCONJ	_	_	_	_	_	_
4	hydrogen	_	NOUN	_	Degree=Pos	_	_	_	_
5	peroxide	_	NOUN	_	Number=Sing	_	_	_	_
6	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	to	_	PART	_	_	_	_	_	_
9	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
10	certain	_	ADJ	_	Degree=Pos	_	_	_	_
11	transcription	_	NOUN	_	Number=Sing	_	_	_	_
12	factors	_	NOUN	_	Number=Plur	_	_	_	_
13	such	_	ADJ	_	Degree=Pos	_	_	_	_
14	as	_	ADP	_	_	_	_	_	_
15	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
16	transcription	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	beta	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	kB	_	PROPN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	)	_	PUNCT	_	_	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	ubiquitous	_	ADJ	_	Degree=Pos	_	_	_	_
14	transcription	_	NOUN	_	Number=Sing	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	pleiotropic	_	ADJ	_	Degree=Pos	_	_	_	_
18	regulator	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	numerous	_	ADJ	_	Degree=Pos	_	_	_	_
21	genes	_	NOUN	_	Number=Plur	_	_	_	_
22	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	immune	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
28	responses	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	factor	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	via	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	selective	_	ADJ	_	Degree=Pos	_	_	_	_
9	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	ubiquination	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	degradation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	I	_	PRON	_	NumType=Card	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kB	_	NOUN	_	Number=Sing	_	_	_	_
21	thereby	_	ADV	_	_	_	_	_	_
22	allowing	_	VERB	_	VerbForm=Ger	_	_	_	_
23	translocation	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	into	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
32	where	_	ADV	_	PronType=Rel	_	_	_	_
33	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
34	upregulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	transcription	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
39	variety	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
42	molecules	_	NOUN	_	Number=Plur	_	_	_	_
43	(	_	PUNCT	_	_	_	_	_	_
44	e.g.	_	ADV	_	_	_	_	_	_
45	ICAM	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	1	_	NUM	_	NumType=Card	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	VCAM	_	PROPN	_	Number=Sing	_	_	_	_
50	-	_	PUNCT	_	_	_	_	_	_
51	1	_	NUM	_	NumType=Card	_	_	_	_
52	)	_	PUNCT	_	_	_	_	_	_
53	,	_	PUNCT	_	_	_	_	_	_
54	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
55	(	_	PUNCT	_	_	_	_	_	_
56	TNF	_	PROPN	_	Number=Sing	_	_	_	_
57	,	_	PUNCT	_	_	_	_	_	_
58	IL	_	PROPN	_	Number=Sing	_	_	_	_
59	-	_	PUNCT	_	_	_	_	_	_
60	1	_	NUM	_	NumType=Card	_	_	_	_
61	,	_	PUNCT	_	_	_	_	_	_
62	IL	_	PROPN	_	Number=Sing	_	_	_	_
63	-	_	PUNCT	_	_	_	_	_	_
64	6	_	NUM	_	NumType=Card	_	_	_	_
65	)	_	PUNCT	_	_	_	_	_	_
66	and	_	CCONJ	_	_	_	_	_	_
67	enzymes	_	NOUN	_	Number=Plur	_	_	_	_
68	(	_	PUNCT	_	_	_	_	_	_
69	iNOS	_	NOUN	_	Number=Sing	_	_	_	_
70	)	_	PUNCT	_	_	_	_	_	_
71	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	proteolytic	_	ADJ	_	Degree=Pos	_	_	_	_
3	degradation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	post	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	translationally	_	ADV	_	_	_	_	_	_
9	modified	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	I	_	PRON	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	to	_	PART	_	_	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	by	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	26S	_	NOUN	_	Number=Sing	_	_	_	_
22	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	upon	_	ADP	_	_	_	_	_	_
3	work	_	NOUN	_	Number=Sing	_	_	_	_
4	from	_	ADP	_	_	_	_	_	_
5	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
6	laboratory	_	PROPN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	propose	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	that	_	SCONJ	_	_	_	_	_	_
11	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	produces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	significant	_	ADJ	_	Degree=Pos	_	_	_	_
20	anti	_	ADJ	_	_	_	_	_	_
21	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	activity	_	NOUN	_	Number=Sing	_	_	_	_
23	which	_	PRON	_	PronType=Rel	_	_	_	_
24	may	_	AUX	_	VerbForm=Fin	_	_	_	_
25	be	_	AUX	_	VerbForm=Inf	_	_	_	_
26	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	transcription	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	certain	_	ADJ	_	Degree=Pos	_	_	_	_
34	pro-inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
35	mediators	_	NOUN	_	Number=Plur	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	adhesion	_	NOUN	_	Number=Sing	_	_	_	_
38	molecules	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013119	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Coexpression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	13	_	NUM	_	NumType=Card	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	genes	_	NOUN	_	Number=Plur	_	_	_	_
12	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
15	physical	_	ADJ	_	Degree=Pos	_	_	_	_
16	linkage	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	cluster	_	NOUN	_	Number=Sing	_	_	_	_
22	on	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
25	5q23	_	NUM	_	NumType=Card	_	_	_	_
26	-	_	SYM	_	_	_	_	_	_
27	31	_	NUM	_	NumType=Card	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	13	_	NUM	_	NumType=Card	_	_	_	_
4	(	_	PUNCT	_	_	_	_	_	_
5	IL	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	13	_	NUM	_	NumType=Card	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	IL	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	4	_	NUM	_	NumType=Card	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
15	produced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	encoded	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	q23	_	NUM	_	NumType=Card	_	_	_	_
25	-	_	SYM	_	_	_	_	_	_
26	31	_	NUM	_	NumType=Card	_	_	_	_
27	region	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	chromosome	_	NOUN	_	Number=Sing	_	_	_	_
31	5	_	NUM	_	NumType=Card	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	regulation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	IL	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	13	_	NUM	_	NumType=Card	_	_	_	_
9	gene	_	NOUN	_	Number=Sing	_	_	_	_
10	expression	_	NOUN	_	Number=Sing	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	T	_	PROPN	_	Number=Sing	_	_	_	_
13	cells	_	NOUN	_	Number=Plur	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
16	isolated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	sequenced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	13	_	NUM	_	NumType=Card	_	_	_	_
24	gene	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	analyzed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
28	5	_	NUM	_	NumType=Card	_	_	_	_
29	'-	_	PUNCT	_	_	_	_	_	_
30	flanking	_	NOUN	_	Number=Sing	_	_	_	_
31	region	_	NOUN	_	Number=Sing	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	potential	_	ADJ	_	Degree=Pos	_	_	_	_
34	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
35	activation	_	NOUN	_	Number=Sing	_	_	_	_
36	elements	_	NOUN	_	Number=Plur	_	_	_	_
37	,	_	PUNCT	_	_	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
40	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
41	expression	_	NOUN	_	Number=Sing	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	nontransformed	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
44	T-lineage	_	NOUN	_	Number=Sing	_	_	_	_
45	cell	_	NOUN	_	Number=Sing	_	_	_	_
46	populations	_	NOUN	_	Number=Plur	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	human	_	ADJ	_	Degree=Pos	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	13	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
8	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	12.5	_	NUM	_	NumType=Card	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kb	_	NOUN	_	Number=Sing	_	_	_	_
12	upstream	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	IL	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	4	_	NUM	_	NumType=Card	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	2	_	NUM	_	NumType=Card	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	kb	_	NOUN	_	Number=Sing	_	_	_	_
23	downstream	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	CpG	_	PROPN	_	Number=Sing	_	_	_	_
27	island	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	IL	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	13	_	NUM	_	NumType=Card	_	_	_	_
5	gene	_	NOUN	_	Number=Sing	_	_	_	_
6	5	_	NUM	_	NumType=Card	_	_	_	_
7	'	_	PUNCT	_	_	_	_	_	_
8	flank	_	NOUN	_	Number=Sing	_	_	_	_
9	region	_	NOUN	_	Number=Sing	_	_	_	_
10	included	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	segment	_	NOUN	_	Number=Sing	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	homology	_	NOUN	_	Number=Sing	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	P	_	NOUN	_	Number=Sing	_	_	_	_
18	elements	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	4	_	NUM	_	NumType=Card	_	_	_	_
24	promoter	_	NOUN	_	Number=Sing	_	_	_	_
25	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
28	activation	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	T	_	PROPN	_	Number=Sing	_	_	_	_
31	cells	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Mutation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	13	_	NUM	_	NumType=Card	_	_	_	_
7	P	_	NOUN	_	Number=Sing	_	_	_	_
8	element	_	NOUN	_	Number=Sing	_	_	_	_
9	site	_	NOUN	_	Number=Sing	_	_	_	_
10	significantly	_	ADV	_	_	_	_	_	_
11	reduced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	IL	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	13	_	NUM	_	NumType=Card	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	response	_	NOUN	_	Number=Sing	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
2	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	IL	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	13	_	NUM	_	NumType=Card	_	_	_	_
7	or	_	CCONJ	_	_	_	_	_	_
8	IL	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	4	_	NUM	_	NumType=Card	_	_	_	_
11	P	_	NOUN	_	Number=Sing	_	_	_	_
12	element	_	NOUN	_	Number=Sing	_	_	_	_
13	sites	_	NOUN	_	Number=Plur	_	_	_	_
14	specifically	_	ADV	_	_	_	_	_	_
15	bound	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	activator	_	NOUN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
22	factor	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	preformed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	NF	_	PROPN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	ATp	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	when	_	ADV	_	PronType=Rel	_	_	_	_
36	incubated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
39	protein	_	NOUN	_	Number=Sing	_	_	_	_
40	extracts	_	NOUN	_	Number=Plur	_	_	_	_
41	from	_	ADP	_	_	_	_	_	_
42	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
43	T	_	NOUN	_	Number=Sing	_	_	_	_
44	cells	_	NOUN	_	Number=Plur	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Similar	_	ADJ	_	Degree=Pos	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	IL	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	4	_	NUM	_	NumType=Card	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	IL	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	13	_	NUM	_	NumType=Card	_	_	_	_
10	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	highest	_	ADJ	_	Degree=Sup	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
16	populations	_	NOUN	_	Number=Plur	_	_	_	_
17	enriched	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	for	_	ADP	_	_	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
22	previously	_	ADV	_	_	_	_	_	_
23	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
24	primed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	vivo	_	NOUN	_	Number=Sing	_	_	_	_
27	or	_	CCONJ	_	_	_	_	_	_
28	in	_	ADP	_	_	_	_	_	_
29	vitro	_	NOUN	_	Number=Sing	_	_	_	_
30	,	_	PUNCT	_	_	_	_	_	_
31	indicating	_	VERB	_	VerbForm=Ger	_	_	_	_
32	that	_	SCONJ	_	_	_	_	_	_
33	priming	_	NOUN	_	Number=Sing	_	_	_	_
34	increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
39	IL	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	13	_	NUM	_	NumType=Card	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	IL	_	PROPN	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	4	_	NUM	_	NumType=Card	_	_	_	_
46	genes	_	NOUN	_	Number=Plur	_	_	_	_
47	in	_	ADP	_	_	_	_	_	_
48	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
49	coordinate	_	ADJ	_	Degree=Pos	_	_	_	_
50	manner	_	NOUN	_	Number=Sing	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	Because	_	SCONJ	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	primed	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
4	T	_	NOUN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	contain	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	higher	_	ADJ	_	Degree=Cmp	_	_	_	_
8	levels	_	NOUN	_	Number=Plur	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	ATp	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	capable	_	ADJ	_	Degree=Pos	_	_	_	_
16	of	_	SCONJ	_	_	_	_	_	_
17	binding	_	VERB	_	Number=Sing	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	P	_	NOUN	_	Number=Sing	_	_	_	_
20	elements	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	4	_	NUM	_	NumType=Card	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	IL	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	13	_	NUM	_	NumType=Card	_	_	_	_
30	promoters	_	NOUN	_	Number=Plur	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	than	_	SCONJ	_	_	_	_	_	_
33	do	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
34	freshly	_	ADV	_	_	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	T	_	NOUN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	,	_	PUNCT	_	_	_	_	_	_
40	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
41	NF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	AT	_	ADP	_	Number=Sing	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	binding	_	NOUN	_	Number=Sing	_	_	_	_
46	P	_	NOUN	_	Number=Sing	_	_	_	_
47	elements	_	NOUN	_	Number=Plur	_	_	_	_
48	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
49	attractive	_	ADJ	_	Degree=Pos	_	_	_	_
50	candidates	_	NOUN	_	Number=Plur	_	_	_	_
51	to	_	PART	_	_	_	_	_	_
52	mediate	_	VERB	_	VerbForm=Inf	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	coordinate	_	ADJ	_	Degree=Pos	_	_	_	_
55	expression	_	NOUN	_	Number=Sing	_	_	_	_
56	of	_	ADP	_	_	_	_	_	_
57	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
58	two	_	NUM	_	NumType=Card	_	_	_	_
59	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
60	genes	_	NOUN	_	Number=Plur	_	_	_	_
61	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013122	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Gene	_	NOUN	_	Number=Sing	_	_	_	_
2	transcription	_	NOUN	_	Number=Sing	_	_	_	_
3	through	_	ADP	_	_	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	G	_	NUM	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	chemoattractant	_	ADJ	_	Number=Sing	_	_	_	_
12	receptors	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Receptors	_	NOUN	_	Number=Plur	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	leukocyte	_	ADJ	_	Number=Sing	_	_	_	_
4	chemoattractants	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	including	_	VERB	_	VerbForm=Ger	_	_	_	_
7	chemokines	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	traditionally	_	ADV	_	_	_	_	_	_
11	considered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	be	_	AUX	_	VerbForm=Inf	_	_	_	_
14	responsible	_	ADJ	_	Degree=Pos	_	_	_	_
15	for	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	special	_	ADJ	_	Degree=Pos	_	_	_	_
20	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
21	functions	_	NOUN	_	Number=Plur	_	_	_	_
22	such	_	ADJ	_	Degree=Pos	_	_	_	_
23	as	_	ADP	_	_	_	_	_	_
24	chemotaxis	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	degranulation	_	NOUN	_	Number=Sing	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	release	_	NOUN	_	Number=Sing	_	_	_	_
31	of	_	ADP	_	_	_	_	_	_
32	superoxide	_	NOUN	_	Number=Sing	_	_	_	_
33	anions	_	NOUN	_	Number=Plur	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
4	G-protein	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	coupled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	serpentine	_	NOUN	_	Number=Sing	_	_	_	_
8	receptors	_	NOUN	_	Number=Plur	_	_	_	_
9	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	found	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	PART	_	_	_	_	_	_
13	transduce	_	VERB	_	VerbForm=Inf	_	_	_	_
14	signals	_	NOUN	_	Number=Plur	_	_	_	_
15	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	translation	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	leukocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	such	_	ADJ	_	Degree=Pos	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	kappa	_	PROPN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	AP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	upon	_	ADP	_	_	_	_	_	_
17	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	with	_	ADP	_	_	_	_	_	_
22	several	_	ADJ	_	Degree=Pos	_	_	_	_
23	chemoattractants	_	NOUN	_	Number=Plur	_	_	_	_
24	at	_	ADP	_	_	_	_	_	_
25	physiologically	_	ADV	_	_	_	_	_	_
26	relevant	_	ADJ	_	Degree=Pos	_	_	_	_
27	concentrations	_	NOUN	_	Number=Plur	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	factors	_	NOUN	_	Number=Plur	_	_	_	_
5	through	_	ADP	_	_	_	_	_	_
6	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
7	receptors	_	NOUN	_	Number=Plur	_	_	_	_
8	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	G	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	protein	_	NOUN	_	Number=Sing	_	_	_	_
12	coupling	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	protein	_	NOUN	_	Number=Sing	_	_	_	_
18	kinases	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	underlying	_	ADJ	_	Degree=Pos	_	_	_	_
3	signaling	_	NOUN	_	Number=Sing	_	_	_	_
4	pathways	_	NOUN	_	Number=Plur	_	_	_	_
5	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	be	_	AUX	_	VerbForm=Inf	_	_	_	_
8	different	_	ADJ	_	Degree=Pos	_	_	_	_
9	from	_	ADP	_	_	_	_	_	_
10	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
11	utilized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	TNF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	alpha	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	better	_	ADJ	_	Degree=Cmp	_	_	_	_
19	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
21	that	_	PRON	_	PronType=Rel	_	_	_	_
22	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	transcription	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	immediate	_	ADJ	_	Degree=Pos	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	early	_	ADJ	_	Degree=Pos	_	_	_	_
29	genes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Chemoattractants	_	NOUN	_	Number=Plur	_	_	_	_
2	stimulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	expression	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	several	_	ADJ	_	Degree=Pos	_	_	_	_
7	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
8	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
9	and	_	CCONJ	_	_	_	_	_	_
10	chemokines	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	which	_	PRON	_	PronType=Rel	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	turn	_	NOUN	_	Number=Sing	_	_	_	_
15	may	_	AUX	_	VerbForm=Fin	_	_	_	_
16	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
17	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
18	respective	_	ADJ	_	Degree=Pos	_	_	_	_
19	receptors	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	initiate	_	VERB	_	VerbForm=Inf	_	_	_	_
22	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	autocrine	_	ADJ	_	Number=Sing	_	_	_	_
24	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
25	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
26	for	_	ADP	_	_	_	_	_	_
27	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
28	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	chemokine	_	ADJ	_	Degree=Pos	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	expression	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013123	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	AML	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	Ets	_	NOUN	_	Number=Sing	_	_	_	_
4	proteins	_	NOUN	_	Number=Plur	_	_	_	_
5	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	alpha1	_	VERB	_	Number=Sing	_	_	_	_
9	germ	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	line	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
3	heavy	_	ADJ	_	Degree=Pos	_	_	_	_
4	chain	_	NOUN	_	Number=Sing	_	_	_	_
5	(	_	PUNCT	_	_	_	_	_	_
6	IgH	_	NOUN	_	Number=Sing	_	_	_	_
7	)	_	PUNCT	_	_	_	_	_	_
8	class	_	NOUN	_	Number=Sing	_	_	_	_
9	switch	_	NOUN	_	Number=Sing	_	_	_	_
10	recombination	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	B	_	NOUN	_	Degree=Pos	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	preferentially	_	ADV	_	_	_	_	_	_
15	targets	_	NOUN	_	Number=Plur	_	_	_	_
16	unrearranged	_	ADJ	_	Degree=Pos	_	_	_	_
17	IgH	_	ADJ	_	Degree=Pos	_	_	_	_
18	genes	_	NOUN	_	Number=Plur	_	_	_	_
19	that	_	PRON	_	PronType=Rel	_	_	_	_
20	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	already	_	ADV	_	_	_	_	_	_
22	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
23	rendered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	transcriptionally	_	ADV	_	_	_	_	_	_
25	active	_	ADJ	_	Degree=Pos	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	germ	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	line	_	NOUN	_	Number=Sing	_	_	_	_
7	IgH	_	ADJ	_	Degree=Pos	_	_	_	_
8	genes	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	intervening	_	VERB	_	VerbForm=Ger	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	I	_	NUM	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	regions	_	NOUN	_	Number=Plur	_	_	_	_
17	upstream	_	ADV	_	_	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
20	switch	_	NOUN	_	Number=Sing	_	_	_	_
21	regions	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
3	alpha1	_	VERB	_	Number=Sing	_	_	_	_
4	promoter	_	NOUN	_	Number=Sing	_	_	_	_
5	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	transcription	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	germ	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	line	_	NOUN	_	Number=Sing	_	_	_	_
13	C	_	NOUN	_	Number=Sing	_	_	_	_
14	alpha1	_	NOUN	_	Degree=Pos	_	_	_	_
15	gene	_	NOUN	_	Number=Sing	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	IgA1	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	mediates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	transforming	_	VERB	_	VerbForm=Ger	_	_	_	_
22	growth	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	(	_	PUNCT	_	_	_	_	_	_
25	TGF	_	PROPN	_	Number=Sing	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	beta1	_	NOUN	_	Number=Sing	_	_	_	_
29	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
32	locus	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	alpha1	_	VERB	_	Number=Sing	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	several	_	ADJ	_	Degree=Pos	_	_	_	_
11	binding	_	NOUN	_	Degree=Pos	_	_	_	_
12	sites	_	NOUN	_	Number=Plur	_	_	_	_
13	for	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	AML	_	NOUN	_	Number=Sing	_	_	_	_
16	/	_	PUNCT	_	_	_	_	_	_
17	PEBP2	_	NOUN	_	Number=Sing	_	_	_	_
18	/	_	PUNCT	_	_	_	_	_	_
19	CBF	_	NOUN	_	Number=Sing	_	_	_	_
20	family	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factors	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	that	_	SCONJ	_	_	_	_	_	_
26	AML	_	NOUN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	Ets	_	NOUN	_	Number=Sing	_	_	_	_
29	proteins	_	NOUN	_	Number=Plur	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	major	_	ADJ	_	Degree=Pos	_	_	_	_
32	regulators	_	NOUN	_	Number=Plur	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	basal	_	ADJ	_	Number=Sing	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	TGF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	beta	_	NOUN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
42	promoter	_	NOUN	_	Number=Sing	_	_	_	_
43	activity	_	NOUN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	constitute	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	starting	_	NOUN	_	Number=Sing	_	_	_	_
6	point	_	NOUN	_	Number=Sing	_	_	_	_
7	for	_	ADP	_	_	_	_	_	_
8	studies	_	NOUN	_	Number=Plur	_	_	_	_
9	to	_	PART	_	_	_	_	_	_
10	elucidate	_	VERB	_	VerbForm=Inf	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
13	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	which	_	PRON	_	PronType=Rel	_	_	_	_
16	TGF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	beta	_	NOUN	_	Number=Sing	_	_	_	_
19	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	IgA	_	NOUN	_	Number=Sing	_	_	_	_
21	production	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013130	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	CD30	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	CD40	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
7	molecule	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	negatively	_	ADV	_	_	_	_	_	_
10	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	CD40	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	mediated	_	VERB	_	Degree=Pos	_	_	_	_
14	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
15	class	_	NOUN	_	Number=Sing	_	_	_	_
16	switching	_	VERB	_	VerbForm=Ger	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	non-antigen	_	ADJ	_	Degree=Pos	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	human	_	ADJ	_	Degree=Pos	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
4	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
5	model	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	germinal	_	ADJ	_	Degree=Pos	_	_	_	_
8	center	_	NOUN	_	Number=Sing	_	_	_	_
9	maturation	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	CL	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	01	_	NUM	_	NumType=Card	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	cells	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	to	_	PART	_	_	_	_	_	_
18	investigate	_	VERB	_	VerbForm=Inf	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	role	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	CD30	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	B	_	NOUN	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	CL	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	01	_	NUM	_	NumType=Card	_	_	_	_
4	cells	_	NOUN	_	Number=Plur	_	_	_	_
5	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	IgM	_	PROPN	_	Number=Sing	_	_	_	_
7	+	_	SYM	_	_	_	_	_	_

1	IgD	_	PROPN	_	Number=Sing	_	_	_	_
2	+	_	SYM	_	_	_	_	_	_
3	CD30	_	NOUN	_	Number=Sing	_	_	_	_
4	+	_	SYM	_	_	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	switch	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	IgG	_	PROPN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	IgA	_	PROPN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	IgE	_	PROPN	_	Number=Sing	_	_	_	_
14	when	_	ADV	_	PronType=Int	_	_	_	_
15	exposed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	CD40L	_	PROPN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Switching	_	NOUN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	hampered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	CD30	_	PROPN	_	Number=Sing	_	_	_	_
6	coengagement	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	possibly	_	ADV	_	_	_	_	_	_
9	through	_	ADP	_	_	_	_	_	_
10	interference	_	NOUN	_	Number=Sing	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	CD40	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
21	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
22	activation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	downstream	_	ADJ	_	Degree=Pos	_	_	_	_
25	C	_	PROPN	_	Number=Sing	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	H	_	NOUN	_	_	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	genes	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	physiological	_	ADJ	_	Degree=Pos	_	_	_	_
3	relevance	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	phenomenon	_	NOUN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	emphasized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	similar	_	ADJ	_	Degree=Pos	_	_	_	_
11	CD30	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	mediated	_	VERB	_	Degree=Pos	_	_	_	_
14	effects	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	naive	_	ADJ	_	Degree=Pos	_	_	_	_
17	B	_	ADJ	_	Degree=Pos	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Expression	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	CD30	_	NOUN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	CD40L	_	NOUN	_	Number=Sing	_	_	_	_
11	but	_	CCONJ	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	B	_	NOUN	_	Degree=Pos	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	coengagement	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	or	_	CCONJ	_	_	_	_	_	_
22	exposure	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	IL	_	PROPN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	6	_	NUM	_	NumType=Card	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	12	_	NUM	_	NumType=Card	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	CD30	_	PROPN	_	Number=Sing	_	_	_	_
6	critically	_	ADV	_	_	_	_	_	_
7	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	CD40	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
12	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	non-antigen	_	ADJ	_	Degree=Pos	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	selected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	human	_	ADJ	_	Degree=Pos	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013134	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Regulation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	kappa	_	VERB	_	Number=Sing	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	alpha	_	PROPN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
15	kappa	_	VERB	_	Number=Sing	_	_	_	_
16	B	_	PROPN	_	Number=Sing	_	_	_	_
17	beta	_	NOUN	_	Number=Sing	_	_	_	_
18	stability	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	must	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	released	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	from	_	ADP	_	_	_	_	_	_
11	cytoplasmic	_	ADJ	_	Degree=Pos	_	_	_	_
12	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
13	molecules	_	NOUN	_	Number=Plur	_	_	_	_
14	(	_	PUNCT	_	_	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	VERB	_	Number=Sing	_	_	_	_
17	Bs	_	NOUN	_	Number=Sing	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	order	_	NOUN	_	Number=Sing	_	_	_	_
21	to	_	PART	_	_	_	_	_	_
22	move	_	VERB	_	VerbForm=Inf	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	to	_	PART	_	_	_	_	_	_
28	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
29	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
30	target	_	NOUN	_	Number=Sing	_	_	_	_
31	genes	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Little	_	ADV	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	known	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
4	about	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
7	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	maintenance	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
12	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
13	NF	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	some	_	DET	_	_	_	_	_	_
19	cell	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	types	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	sustained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	NF	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	after	_	ADP	_	_	_	_	_	_
32	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
2	turnover	_	NOUN	_	Number=Sing	_	_	_	_
3	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
5	implicated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	regulation	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
11	NF	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	mature	_	ADJ	_	Degree=Pos	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	therefore	_	ADV	_	_	_	_	_	_
3	compared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	turnover	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	kappa	_	VERB	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	PROPN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
13	kappa	_	VERB	_	Number=Sing	_	_	_	_
14	B	_	PROPN	_	Number=Sing	_	_	_	_
15	beta	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	mature	_	ADJ	_	Degree=Pos	_	_	_	_
18	B	_	ADJ	_	Degree=Pos	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Both	_	DET	_	_	_	_	_	_
2	proteins	_	NOUN	_	Number=Plur	_	_	_	_
3	display	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	high	_	ADJ	_	Degree=Pos	_	_	_	_
6	turnover	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	B	_	ADJ	_	Number=Sing	_	_	_	_
9	cells	_	NOUN	_	Number=Plur	_	_	_	_
10	although	_	SCONJ	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	kappa	_	VERB	_	Number=Sing	_	_	_	_
13	B	_	PROPN	_	Number=Sing	_	_	_	_
14	beta	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	considerably	_	ADV	_	_	_	_	_	_
17	more	_	ADV	_	_	_	_	_	_
18	stable	_	ADJ	_	Degree=Pos	_	_	_	_
19	than	_	SCONJ	_	_	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	kappa	_	VERB	_	Number=Sing	_	_	_	_
22	B	_	PROPN	_	Number=Sing	_	_	_	_
23	alpha	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	half	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	life	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	both	_	DET	_	_	_	_	_	_
7	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
8	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	increased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	all	_	DET	_	_	_	_	_	_
5	other	_	ADJ	_	Degree=Pos	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
12	kappa	_	NOUN	_	Number=Sing	_	_	_	_
13	B	_	NOUN	_	Number=Sing	_	_	_	_
14	molecules	_	NOUN	_	Number=Plur	_	_	_	_
15	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	relatively	_	ADV	_	_	_	_	_	_
18	stable	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	both	_	DET	_	_	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	types	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	elevated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
3	turnover	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	kappa	_	VERB	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	Namalwa	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
18	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	thus	_	ADV	_	_	_	_	_	_
21	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	to	_	PART	_	_	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	driven	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	same	_	ADJ	_	Degree=Pos	_	_	_	_
28	degradation	_	NOUN	_	Number=Sing	_	_	_	_
29	machinery	_	NOUN	_	Number=Sing	_	_	_	_
30	as	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	slower	_	ADJ	_	Degree=Cmp	_	_	_	_
33	turnover	_	NOUN	_	Number=Sing	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	non-B	_	ADJ	_	Degree=Pos	_	_	_	_
36	cells	_	NOUN	_	Number=Plur	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	investigated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	processes	_	NOUN	_	Number=Plur	_	_	_	_
7	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	NF	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	kappa	_	PROPN	_	Number=Sing	_	_	_	_
15	B.	_	PROPN	_	Number=Sing	_	_	_	_
16	TNF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	alpha	_	NOUN	_	Number=Sing	_	_	_	_
19	signaling	_	NOUN	_	Number=Sing	_	_	_	_
20	leads	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
24	depletion	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	cellular	_	ADJ	_	Number=Sing	_	_	_	_
27	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
28	kappa	_	VERB	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	beta	_	NOUN	_	Number=Sing	_	_	_	_
31	pools	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
2	kappa	_	VERB	_	Number=Sing	_	_	_	_
3	B	_	PROPN	_	Number=Sing	_	_	_	_
4	alpha	_	PROPN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	efficiently	_	ADV	_	_	_	_	_	_
7	resynthesized	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	whereas	_	SCONJ	_	_	_	_	_	_
9	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
10	kappa	_	VERB	_	Number=Sing	_	_	_	_
11	B	_	DET	_	Number=Sing	_	_	_	_
12	beta	_	NOUN	_	Number=Sing	_	_	_	_
13	levels	_	NOUN	_	Number=Plur	_	_	_	_
14	stay	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	low	_	ADV	_	Degree=Pos	_	_	_	_
16	for	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	prolonged	_	VERB	_	Degree=Pos	_	_	_	_
19	time	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	binding	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	detected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	several	_	ADJ	_	Degree=Pos	_	_	_	_
12	hours	_	NOUN	_	Number=Plur	_	_	_	_
13	after	_	ADP	_	_	_	_	_	_
14	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	found	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	removal	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	TNF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	containing	_	VERB	_	VerbForm=Ger	_	_	_	_
11	medium	_	NOUN	_	Number=Sing	_	_	_	_
12	causes	_	NOUN	_	Number=Plur	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	rapid	_	ADJ	_	Degree=Pos	_	_	_	_
15	decrease	_	NOUN	_	Number=Sing	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	phosphoform	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	newly	_	ADV	_	_	_	_	_	_
5	synthesized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
7	kappa	_	VERB	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	alpha	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	visible	_	ADJ	_	Degree=Pos	_	_	_	_
12	when	_	ADV	_	PronType=Int	_	_	_	_
13	degradation	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
17	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	new	_	ADJ	_	Degree=Pos	_	_	_	_
21	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
22	kappa	_	VERB	_	Number=Sing	_	_	_	_
23	B	_	PROPN	_	Number=Sing	_	_	_	_
24	alpha	_	NOUN	_	Number=Sing	_	_	_	_
25	displays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	same	_	ADJ	_	Degree=Pos	_	_	_	_
28	properties	_	NOUN	_	Number=Plur	_	_	_	_
29	regarding	_	VERB	_	VerbForm=Ger	_	_	_	_
30	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	degradation	_	NOUN	_	Number=Sing	_	_	_	_
33	in	_	ADP	_	_	_	_	_	_
34	response	_	NOUN	_	Number=Sing	_	_	_	_
35	to	_	ADP	_	_	_	_	_	_
36	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
37	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
38	inducer	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	There	_	PRON	_	_	_	_	_	_
2	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	no	_	DET	_	_	_	_	_	_
4	significant	_	ADJ	_	Degree=Pos	_	_	_	_
5	difference	_	NOUN	_	Number=Sing	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	turnover	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	pre	_	X	_	_	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	post	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	inductive	_	NOUN	_	Number=Sing	_	_	_	_
16	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
17	kappa	_	VERB	_	Number=Sing	_	_	_	_
18	B	_	PROPN	_	Number=Sing	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	resynthesis	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
8	kappa	_	VERB	_	Number=Sing	_	_	_	_
9	B	_	PROPN	_	Number=Sing	_	_	_	_
10	alpha	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	removal	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	stimulus	_	NOUN	_	Number=Sing	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	obligatory	_	ADJ	_	Degree=Pos	_	_	_	_
18	steps	_	NOUN	_	Number=Plur	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	inactivation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
24	NF	_	PROPN	_	Number=Sing	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B.	_	PROPN	_	Number=Sing	_	_	_	_
27	Document	_	NOUN	_	Number=Sing	_	_	_	_
28	0030013136	_	NUM	_	NumType=Card	_	_	_	_
29	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	Vpr	_	NOUN	_	Number=Sing	_	_	_	_
5	suppresses	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	immune	_	ADJ	_	Degree=Pos	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
10	through	_	ADP	_	_	_	_	_	_
11	regulation	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	[	_	PUNCT	_	_	_	_	_	_
18	see	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
19	comments	_	NOUN	_	Number=Plur	_	_	_	_
20	]	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	HIV	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	accessory	_	ADJ	_	Degree=Pos	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	product	_	NOUN	_	Number=Sing	_	_	_	_
8	Vpr	_	PROPN	_	Number=Sing	_	_	_	_
9	can	_	AUX	_	VerbForm=Fin	_	_	_	_
10	influence	_	VERB	_	VerbForm=Inf	_	_	_	_
11	viral	_	ADJ	_	Degree=Pos	_	_	_	_
12	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	SCONJ	_	_	_	_	_	_
14	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
15	viral	_	ADJ	_	Degree=Pos	_	_	_	_
16	replication	_	NOUN	_	Number=Sing	_	_	_	_
17	as	_	ADV	_	_	_	_	_	_
18	well	_	ADV	_	Degree=Pos	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	host	_	ADJ	_	Degree=Pos	_	_	_	_
21	cell	_	NOUN	_	Number=Sing	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	investigated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	Vpr	_	PROPN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	host	_	NOUN	_	Number=Sing	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	activation	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	confirm	_	VERB	_	VerbForm=Inf	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
16	influences	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	also	_	ADV	_	_	_	_	_	_
6	found	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	Vpr	_	PROPN	_	Number=Sing	_	_	_	_
9	modulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	T-cell	_	PROPN	_	Number=Sing	_	_	_	_
11	receptor	_	NOUN	_	Number=Sing	_	_	_	_
12	(	_	PUNCT	_	_	_	_	_	_
13	TCR	_	NOUN	_	Number=Sing	_	_	_	_
14	)	_	PUNCT	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	triggered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
20	manner	_	NOUN	_	Number=Sing	_	_	_	_
21	similar	_	ADJ	_	Degree=Pos	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	absence	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	TCR	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
8	activation	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	Vpr	_	PROPN	_	Number=Sing	_	_	_	_
11	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
13	whereas	_	SCONJ	_	_	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
16	presence	_	NOUN	_	Number=Sing	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	Vpr	_	PROPN	_	Number=Sing	_	_	_	_
19	interrupts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	expected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	induction	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	regulation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	to	_	ADP	_	_	_	_	_	_
8	Vpr	_	PROPN	_	Number=Sing	_	_	_	_
9	suppression	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	NF	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	via	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	induction	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
21	kappa	_	PROPN	_	Number=Sing	_	_	_	_
22	B	_	PROPN	_	Number=Sing	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	NF	_	PROPN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B.	_	PROPN	_	Number=Sing	_	_	_	_
31	Further	_	ADV	_	_	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	Vpr	_	PROPN	_	Number=Sing	_	_	_	_
34	suppresses	_	VERB	_	Number=Plur	_	_	_	_
35	expression	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	IL	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	2	_	NUM	_	NumType=Card	_	_	_	_
40	,	_	PUNCT	_	_	_	_	_	_
41	IL	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	10	_	NUM	_	NumType=Card	_	_	_	_
44	,	_	PUNCT	_	_	_	_	_	_
45	IL	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	12	_	NUM	_	NumType=Card	_	_	_	_
48	,	_	PUNCT	_	_	_	_	_	_
49	TNF	_	PROPN	_	Number=Sing	_	_	_	_
50	alpha	_	PROPN	_	Number=Sing	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	IL	_	PROPN	_	Number=Sing	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	4	_	NUM	_	NumType=Card	_	_	_	_
55	,	_	PUNCT	_	_	_	_	_	_
56	all	_	DET	_	_	_	_	_	_
57	of	_	ADP	_	_	_	_	_	_
58	which	_	PRON	_	PronType=Rel	_	_	_	_
59	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
60	NF	_	PROPN	_	Number=Sing	_	_	_	_
61	-	_	PUNCT	_	_	_	_	_	_
62	kappa	_	PROPN	_	Number=Sing	_	_	_	_
63	B	_	NOUN	_	Number=Sing	_	_	_	_
64	-	_	PUNCT	_	_	_	_	_	_
65	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
66	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	Vpr	_	PROPN	_	Number=Sing	_	_	_	_
5	could	_	AUX	_	VerbForm=Fin	_	_	_	_
6	be	_	AUX	_	VerbForm=Inf	_	_	_	_
7	reversed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	RU486	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	finding	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	Vpr	_	PROPN	_	Number=Sing	_	_	_	_
5	can	_	AUX	_	VerbForm=Fin	_	_	_	_
6	regulate	_	VERB	_	VerbForm=Inf	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	PROPN	_	Number=Sing	_	_	_	_
10	B	_	PROPN	_	Number=Sing	_	_	_	_
11	supports	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
14	that	_	SCONJ	_	_	_	_	_	_
15	some	_	DET	_	_	_	_	_	_
16	aspects	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	viral	_	ADJ	_	Degree=Pos	_	_	_	_
19	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
20	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	consequence	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	cell	_	NOUN	_	Number=Sing	_	_	_	_
25	dysregulation	_	NOUN	_	Number=Sing	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	Vpr	_	PROPN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013138	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Differential	_	ADJ	_	Degree=Pos	_	_	_	_
2	interaction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factors	_	NOUN	_	Number=Plur	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	pp52	_	NOUN	_	Number=Sing	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	B	_	ADJ	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	T	_	PROPN	_	Number=Sing	_	_	_	_
17	cells	_	NOUN	_	Number=Plur	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	cytoskeleton	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	NOUN	_	Number=Sing	_	_	_	_
9	pp52	_	NOUN	_	Number=Sing	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	LSP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	WP	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	34	_	NUM	_	NumType=Card	_	_	_	_
18	)	_	PUNCT	_	_	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	widely	_	ADV	_	_	_	_	_	_
22	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	multiple	_	ADJ	_	Degree=Pos	_	_	_	_
25	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
26	lineages	_	NOUN	_	Number=Plur	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	including	_	VERB	_	VerbForm=Ger	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	T	_	NOUN	_	Number=Sing	_	_	_	_
32	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	granulocytes	_	NOUN	_	Number=Plur	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	previously	_	ADV	_	_	_	_	_	_
3	detected	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	tissue	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	specific	_	ADJ	_	Degree=Pos	_	_	_	_
8	promoter	_	NOUN	_	Number=Sing	_	_	_	_
9	preceding	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	exon	_	NOUN	_	Number=Sing	_	_	_	_
12	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	N	_	PROPN	_	Number=Sing	_	_	_	_
15	terminus	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	pp52	_	NUM	_	NumType=Card	_	_	_	_
19	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
20	protein	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Here	_	ADV	_	PronType=Dem	_	_	_	_
2	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
3	describe	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	functional	_	ADJ	_	Degree=Pos	_	_	_	_
6	characterization	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	identification	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	factors	_	NOUN	_	Number=Plur	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	B	_	ADJ	_	Degree=Pos	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	that	_	PRON	_	PronType=Rel	_	_	_	_
21	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	pp52	_	NOUN	_	Number=Sing	_	_	_	_
3	promoter	_	NOUN	_	Number=Sing	_	_	_	_
4	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	initiator	_	NOUN	_	Number=Sing	_	_	_	_
7	specifying	_	VERB	_	VerbForm=Ger	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	unique	_	ADJ	_	Degree=Pos	_	_	_	_
10	5'	_	NOUN	_	NumType=Card	_	_	_	_
11	terminus	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	pp52	_	NUM	_	Number=Sing	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	tandem	_	VERB	_	Number=Sing	_	_	_	_
17	pairs	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	Ets	_	NOUN	_	Number=Sing	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	SP1	_	NOUN	_	Number=Sing	_	_	_	_
22	motifs	_	NOUN	_	Number=Plur	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	lone	_	ADJ	_	Degree=Pos	_	_	_	_
27	C	_	NOUN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	EBP	_	NOUN	_	Number=Sing	_	_	_	_
30	motif	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	All	_	DET	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	motifs	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	essential	_	ADJ	_	Degree=Pos	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	collectively	_	ADV	_	_	_	_	_	_
8	control	_	VERB	_	Number=Sing	_	_	_	_
9	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
10	activity	_	NOUN	_	Number=Sing	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	DNA	_	PROPN	_	Number=Sing	_	_	_	_
2	binding	_	NOUN	_	Number=Sing	_	_	_	_
3	studies	_	NOUN	_	Number=Plur	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	Ab	_	PROPN	_	Number=Sing	_	_	_	_
6	supershift	_	NOUN	_	Number=Sing	_	_	_	_
7	assays	_	NOUN	_	Number=Plur	_	_	_	_
8	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	SCONJ	_	_	_	_	_	_
10	different	_	ADJ	_	Degree=Pos	_	_	_	_
11	combinations	_	NOUN	_	Number=Plur	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	factors	_	NOUN	_	Number=Plur	_	_	_	_
14	interact	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
17	motifs	_	NOUN	_	Number=Plur	_	_	_	_
18	in	_	ADP	_	_	_	_	_	_
19	B	_	ADJ	_	Degree=Pos	_	_	_	_
20	cells	_	NOUN	_	Number=Plur	_	_	_	_
21	vs	_	ADP	_	_	_	_	_	_
22	T	_	NOUN	_	Number=Sing	_	_	_	_
23	cells	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	Ets	_	NOUN	_	Number=Sing	_	_	_	_
3	motifs	_	NOUN	_	Number=Plur	_	_	_	_
4	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	preferentially	_	ADV	_	_	_	_	_	_
6	bound	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	ADP	_	_	_	_	_	_
8	PU	_	PROPN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	B	_	ADJ	_	Degree=Pos	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	extracts	_	NOUN	_	Number=Plur	_	_	_	_
15	from	_	ADP	_	_	_	_	_	_
16	all	_	DET	_	_	_	_	_	_
17	stages	_	NOUN	_	Number=Plur	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	development	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whereas	_	SCONJ	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	different	_	ADJ	_	Degree=Pos	_	_	_	_
24	Ets	_	NOUN	_	Number=Sing	_	_	_	_
25	family	_	NOUN	_	Number=Sing	_	_	_	_
26	member	_	NOUN	_	Number=Sing	_	_	_	_
27	reacts	_	VERB	_	Number=Plur	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
30	motifs	_	NOUN	_	Number=Plur	_	_	_	_
31	in	_	ADP	_	_	_	_	_	_
32	T	_	PROPN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	extracts	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	C/EBP	_	NOUN	_	Number=Sing	_	_	_	_
3	motif	_	NOUN	_	Number=Sing	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	bound	_	ADJ	_	Degree=Pos	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	Ig	_	PROPN	_	Number=Sing	_	_	_	_
8	/	_	PUNCT	_	_	_	_	_	_
9	EBP	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	1	_	NUM	_	NumType=Card	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	pre	_	X	_	_	_	_	_	_
14	-B	_	NOUN	_	Number=Sing	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	T	_	NOUN	_	Number=Sing	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	extracts	_	NOUN	_	Number=Plur	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	but	_	CCONJ	_	_	_	_	_	_
22	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	replaced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
26	factor	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	IL	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	6beta	_	PROPN	_	Number=Sing	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
33	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
34	factor	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	IL	_	PROPN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	6beta-Ig	_	NOUN	_	Number=Sing	_	_	_	_
39	/	_	PUNCT	_	_	_	_	_	_
40	EBP	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	1	_	NUM	_	NumType=Card	_	_	_	_
43	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
44	in	_	ADP	_	_	_	_	_	_
45	plasmacytoma	_	ADJ	_	Number=Sing	_	_	_	_
46	cell	_	NOUN	_	Number=Sing	_	_	_	_
47	extracts	_	NOUN	_	Number=Plur	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Despite	_	ADP	_	_	_	_	_	_
2	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
3	reported	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	role	_	NOUN	_	Number=Sing	_	_	_	_
5	as	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	negative	_	ADJ	_	Degree=Pos	_	_	_	_
8	regulator	_	NOUN	_	Number=Sing	_	_	_	_
9	of	_	ADP	_	_	_	_	_	_
10	transcription	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	Ig	_	PROPN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	EBP	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	exert	_	VERB	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	stimulatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	effect	_	NOUN	_	Number=Sing	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	reveal	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	features	_	NOUN	_	Number=Plur	_	_	_	_
6	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	pp52	_	NOUN	_	Number=Sing	_	_	_	_
9	promoter	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	B	_	ADJ	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	T	_	PROPN	_	Number=Sing	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	foundation	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	SCONJ	_	_	_	_	_	_
20	determining	_	VERB	_	VerbForm=Ger	_	_	_	_
21	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
22	regulation	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
25	promoter	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	other	_	ADJ	_	Degree=Pos	_	_	_	_
28	leukocyte	_	NOUN	_	Number=Sing	_	_	_	_
29	lineages	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013140	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Isolation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	rel-related	_	ADJ	_	Degree=Pos	_	_	_	_
5	human	_	ADJ	_	Degree=Pos	_	_	_	_
6	cDNA	_	NOUN	_	Number=Sing	_	_	_	_
7	that	_	PRON	_	PronType=Rel	_	_	_	_
8	potentially	_	ADV	_	_	_	_	_	_
9	encodes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	65	_	NUM	_	NumType=Card	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	kD	_	NOUN	_	Number=Sing	_	_	_	_
14	subunit	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	[	_	PUNCT	_	_	_	_	_	_
21	published	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	erratum	_	NOUN	_	Number=Sing	_	_	_	_
23	appears	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	Science	_	PROPN	_	Number=Sing	_	_	_	_
26	1991	_	NUM	_	NumType=Card	_	_	_	_
27	Oct	_	PROPN	_	Number=Sing	_	_	_	_
28	4;254	_	NUM	_	NumType=Card	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	5028	_	NUM	_	NumType=Card	_	_	_	_
31	):11	_	PUNCT	_	_	_	_	_	_
32	]	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	DNA	_	NOUN	_	Number=Sing	_	_	_	_
3	probe	_	NOUN	_	Number=Sing	_	_	_	_
4	that	_	PRON	_	PronType=Rel	_	_	_	_
5	spanned	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	domain	_	NOUN	_	Number=Sing	_	_	_	_
8	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	among	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	proto	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	oncogene	_	NOUN	_	Number=Sing	_	_	_	_
14	c-rel	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	Drosophila	_	PROPN	_	Number=Sing	_	_	_	_
18	morphogen	_	NOUN	_	Number=Sing	_	_	_	_
19	dorsal	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	p50	_	NOUN	_	Number=Sing	_	_	_	_
24	DNA	_	PROPN	_	Number=Sing	_	_	_	_
25	binding	_	VERB	_	Number=Sing	_	_	_	_
26	subunit	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	NF	_	PROPN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	kappa	_	NOUN	_	Number=Sing	_	_	_	_
31	B	_	NOUN	_	Number=Sing	_	_	_	_
32	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
33	generated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	from	_	ADP	_	_	_	_	_	_
35	Jurkat	_	PROPN	_	Number=Sing	_	_	_	_
36	T	_	PROPN	_	Number=Sing	_	_	_	_
37	cell	_	NOUN	_	Number=Sing	_	_	_	_
38	complementary	_	ADJ	_	Degree=Pos	_	_	_	_
39	DNA	_	NOUN	_	Number=Sing	_	_	_	_
40	with	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	polymerase	_	NOUN	_	Number=Sing	_	_	_	_
43	chain	_	NOUN	_	Number=Sing	_	_	_	_
44	reaction	_	NOUN	_	Number=Sing	_	_	_	_
45	(	_	PUNCT	_	_	_	_	_	_
46	PCR	_	NOUN	_	Number=Sing	_	_	_	_
47	)	_	PUNCT	_	_	_	_	_	_
48	and	_	CCONJ	_	_	_	_	_	_
49	degenerate	_	ADJ	_	Degree=Pos	_	_	_	_
50	oligonucleotides	_	NOUN	_	Number=Plur	_	_	_	_
51	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	probe	_	NOUN	_	Number=Sing	_	_	_	_
3	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
4	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	to	_	PART	_	_	_	_	_	_
6	identify	_	VERB	_	VerbForm=Inf	_	_	_	_
7	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	rel	_	ADV	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	related	_	ADJ	_	Degree=Pos	_	_	_	_
11	complementary	_	ADJ	_	Degree=Pos	_	_	_	_
12	DNA	_	NOUN	_	Number=Sing	_	_	_	_
13	that	_	PRON	_	PronType=Rel	_	_	_	_
14	hybridized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	2.6	_	NUM	_	NumType=Card	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kilobase	_	NOUN	_	Number=Sing	_	_	_	_
20	messenger	_	NOUN	_	Number=Sing	_	_	_	_
21	RNA	_	PROPN	_	Number=Sing	_	_	_	_
22	present	_	VERB	_	Degree=Pos	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	T	_	NOUN	_	Number=Sing	_	_	_	_
26	and	_	CCONJ	_	_	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	vitro	_	NOUN	_	Number=Sing	_	_	_	_
3	transcription	_	NOUN	_	Number=Sing	_	_	_	_
4	and	_	CCONJ	_	_	_	_	_	_
5	translation	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	complementary	_	ADJ	_	Degree=Pos	_	_	_	_
9	DNA	_	NOUN	_	Number=Sing	_	_	_	_
10	resulted	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	apparent	_	ADJ	_	Degree=Pos	_	_	_	_
20	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
21	size	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	65	_	NUM	_	NumType=Card	_	_	_	_
24	kilodaltons	_	NOUN	_	Number=Plur	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	kD	_	NOUN	_	Number=Sing	_	_	_	_
27	)	_	PUNCT	_	_	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	translated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	protein	_	NOUN	_	Number=Sing	_	_	_	_
4	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	weak	_	ADJ	_	Degree=Pos	_	_	_	_
6	DNA	_	PROPN	_	Number=Sing	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	with	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	specificity	_	NOUN	_	Number=Sing	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	binding	_	NOUN	_	Number=Sing	_	_	_	_
16	motif	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	complex	_	NOUN	_	Number=Sing	_	_	_	_
6	comigrated	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	complex	_	NOUN	_	Number=Sing	_	_	_	_
10	obtained	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	purified	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	p65	_	NOUN	_	Number=Sing	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappa	_	NOUN	_	Number=Sing	_	_	_	_
19	B	_	NOUN	_	Number=Sing	_	_	_	_
20	subunit	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
24	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
27	kappa	_	VERB	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	alpha	_	NOUN	_	Number=Sing	_	_	_	_
31	and	_	CCONJ	_	_	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	beta	_	NOUN	_	Number=Sing	_	_	_	_
34	proteins	_	NOUN	_	Number=Plur	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	65	_	NUM	_	NumType=Card	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kD	_	NOUN	_	Number=Sing	_	_	_	_
8	protein	_	NOUN	_	Number=Sing	_	_	_	_
9	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	p50	_	NUM	_	Number=Sing	_	_	_	_
13	subunit	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappa	_	PROPN	_	Number=Sing	_	_	_	_
18	B	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	kappa	_	NOUN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	probe	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	PART	_	_	_	_	_	_
25	form	_	VERB	_	VerbForm=Inf	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	complex	_	NOUN	_	Number=Sing	_	_	_	_
28	with	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	same	_	ADJ	_	Degree=Pos	_	_	_	_
31	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
32	mobility	_	NOUN	_	Number=Sing	_	_	_	_
33	as	_	ADP	_	_	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	NF	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	kappa	_	NOUN	_	Number=Sing	_	_	_	_
38	B	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	DNA	_	PROPN	_	Number=Sing	_	_	_	_
41	complex	_	NOUN	_	Number=Sing	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	rel	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	related	_	ADJ	_	Degree=Pos	_	_	_	_
6	65	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kD	_	NOUN	_	Number=Sing	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	may	_	AUX	_	VerbForm=Fin	_	_	_	_
11	represent	_	VERB	_	VerbForm=Inf	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	p65	_	NUM	_	Number=Sing	_	_	_	_
14	subunit	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	active	_	ADJ	_	Degree=Pos	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	NOUN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	transcription	_	NOUN	_	Number=Sing	_	_	_	_
23	factor	_	NOUN	_	Number=Sing	_	_	_	_
24	complex	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013143	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inhibition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
4	ester	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
8	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
9	by	_	ADP	_	_	_	_	_	_
10	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
11	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	down	_	ADP	_	_	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	regulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	c	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	fos	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	c	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	jun	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	AP	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	SYM	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Previous	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	shown	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
6	treatment	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	human	_	ADJ	_	Degree=Pos	_	_	_	_
9	myeloid	_	NOUN	_	Degree=Pos	_	_	_	_
10	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	with	_	ADP	_	_	_	_	_	_
13	12-O-tetradecanoylphorbol	_	NUM	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	13	_	NUM	_	NumType=Card	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	acetate	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	TPA	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
23	with	_	ADP	_	_	_	_	_	_
24	induction	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
27	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	expression	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
33	and	_	CCONJ	_	_	_	_	_	_
34	c	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	fos	_	ADP	_	_	_	_	_	_
37	early	_	ADJ	_	Degree=Pos	_	_	_	_
38	response	_	NOUN	_	Number=Sing	_	_	_	_
39	genes	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	present	_	ADJ	_	Degree=Pos	_	_	_	_
3	work	_	NOUN	_	Number=Sing	_	_	_	_
4	demonstrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
8	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
9	inhibits	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	TPA	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	increases	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	c	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	jun	_	NOUN	_	Number=Sing	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	c	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	fos	_	ADP	_	_	_	_	_	_
22	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	U	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	937	_	NUM	_	NumType=Card	_	_	_	_
28	leukemia	_	PROPN	_	Number=Sing	_	_	_	_
29	cells	_	NOUN	_	Number=Plur	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	block	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	appearance	_	NOUN	_	Number=Sing	_	_	_	_
10	of	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
13	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	including	_	VERB	_	VerbForm=Ger	_	_	_	_
16	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	TPA	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	increases	_	NOUN	_	Number=Plur	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	lamin	_	NOUN	_	Number=Sing	_	_	_	_
24	A	_	NOUN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	lamin	_	ADJ	_	Number=Sing	_	_	_	_
27	C	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	vimentin	_	ADJ	_	Degree=Pos	_	_	_	_
31	transcripts	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Other	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	demonstrated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	TPA	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	expression	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	c-jun	_	NOUN	_	Number=Sing	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	c	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	fos	_	ADP	_	Number=Sing	_	_	_	_
20	genes	_	NOUN	_	Number=Plur	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	myeloid	_	ADJ	_	Degree=Pos	_	_	_	_
23	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
24	cells	_	NOUN	_	Number=Plur	_	_	_	_
25	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
26	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	by	_	ADP	_	_	_	_	_	_
28	protein	_	NOUN	_	Number=Sing	_	_	_	_
29	kinase	_	NOUN	_	Number=Sing	_	_	_	_
30	C	_	NOUN	_	Number=Sing	_	_	_	_
31	(	_	PUNCT	_	_	_	_	_	_
32	PKC	_	PROPN	_	Number=Sing	_	_	_	_
33	)	_	PUNCT	_	_	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	finding	_	NOUN	_	Number=Sing	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
5	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
6	no	_	DET	_	_	_	_	_	_
7	effect	_	NOUN	_	Number=Sing	_	_	_	_
8	on	_	ADP	_	_	_	_	_	_
9	TPA	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	PKC	_	PROPN	_	Number=Sing	_	_	_	_
15	suggests	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	that	_	SCONJ	_	_	_	_	_	_
17	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
18	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
19	inhibits	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	signals	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
21	downstream	_	ADV	_	Degree=Pos	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	parallel	_	ADJ	_	Degree=Pos	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
26	enzyme	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	run	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	on	_	ADP	_	_	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	:	_	PUNCT	_	_	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	1	_	X	_	_	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	induction	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	c	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	jun	_	NOUN	_	Number=Sing	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	c	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	fos	_	ADP	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	TPA	_	PROPN	_	Number=Sing	_	_	_	_
24	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
25	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
26	by	_	ADP	_	_	_	_	_	_
27	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
28	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	2	_	X	_	_	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	TPA	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
36	expression	_	NOUN	_	Number=Sing	_	_	_	_
37	of	_	ADP	_	_	_	_	_	_
38	c	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	jun	_	NOUN	_	Number=Sing	_	_	_	_
41	and	_	CCONJ	_	_	_	_	_	_
42	c	_	NOUN	_	Number=Sing	_	_	_	_
43	-	_	PUNCT	_	_	_	_	_	_
44	fos	_	NOUN	_	Number=Sing	_	_	_	_
45	does	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
46	not	_	PART	_	_	_	_	_	_
47	require	_	VERB	_	VerbForm=Inf	_	_	_	_
48	protein	_	NOUN	_	Number=Sing	_	_	_	_
49	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
50	,	_	PUNCT	_	_	_	_	_	_
51	and	_	CCONJ	_	_	_	_	_	_
52	(	_	PUNCT	_	_	_	_	_	_
53	3	_	X	_	_	_	_	_	_
54	)	_	PUNCT	_	_	_	_	_	_
55	TPA	_	NOUN	_	Number=Sing	_	_	_	_
56	-	_	PUNCT	_	_	_	_	_	_
57	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
58	expression	_	NOUN	_	Number=Sing	_	_	_	_
59	of	_	ADP	_	_	_	_	_	_
60	both	_	DET	_	_	_	_	_	_
61	genes	_	NOUN	_	Number=Plur	_	_	_	_
62	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
63	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
64	at	_	ADP	_	_	_	_	_	_
65	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
66	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
67	level	_	NOUN	_	Number=Sing	_	_	_	_
68	by	_	ADP	_	_	_	_	_	_
69	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
70	.	_	PUNCT	_	_	_	_	_	_

1	To	_	PART	_	_	_	_	_	_
2	further	_	ADV	_	_	_	_	_	_
3	define	_	VERB	_	VerbForm=Inf	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	effects	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
8	at	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	molecular	_	ADJ	_	Degree=Pos	_	_	_	_
11	level	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
14	prepared	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	series	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	c	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	jun	_	NOUN	_	Number=Sing	_	_	_	_
22	promoter	_	NOUN	_	Number=Sing	_	_	_	_
23	fragments	_	NOUN	_	Number=Plur	_	_	_	_
24	linked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	to	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	chloramphenicol	_	NOUN	_	Number=Sing	_	_	_	_
28	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
29	(	_	PUNCT	_	_	_	_	_	_
30	CAT	_	NOUN	_	Number=Sing	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	gene	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Increases	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
2	in	_	ADP	_	_	_	_	_	_
3	CAT	_	NOUN	_	Number=Sing	_	_	_	_
4	activity	_	NOUN	_	Number=Sing	_	_	_	_
5	during	_	ADP	_	_	_	_	_	_
6	transient	_	ADJ	_	Degree=Pos	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
10	constructs	_	NOUN	_	Number=Plur	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	TPA	_	PROPN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	U	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	937	_	NUM	_	NumType=Card	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	could	_	AUX	_	VerbForm=Fin	_	_	_	_
20	be	_	AUX	_	VerbForm=Inf	_	_	_	_
21	assigned	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	to	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	region	_	NOUN	_	Number=Sing	_	_	_	_
25	(	_	PUNCT	_	_	_	_	_	_
26	-	_	SYM	_	_	_	_	_	_
27	97	_	NUM	_	NumType=Card	_	_	_	_
28	to	_	ADP	_	_	_	_	_	_
29	-	_	SYM	_	_	_	_	_	_
30	20	_	NUM	_	NumType=Card	_	_	_	_
31	)	_	PUNCT	_	_	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	promoter	_	NOUN	_	Number=Sing	_	_	_	_
35	that	_	PRON	_	PronType=Rel	_	_	_	_
36	contains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	AP	_	NOUN	_	Number=Sing	_	_	_	_
39	-	_	PUNCT	_	_	_	_	_	_
40	1	_	NUM	_	NumType=Card	_	_	_	_
41	binding	_	NOUN	_	Number=Sing	_	_	_	_
42	site	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	induction	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	CAT	_	NOUN	_	Number=Sing	_	_	_	_
5	activity	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	sensitive	_	ADJ	_	Degree=Pos	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
10	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	dexamethasone	_	NOUN	_	Number=Sing	_	_	_	_
6	down	_	ADP	_	_	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	regulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	TPA	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	transcription	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	c	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	jun	_	NOUN	_	Number=Sing	_	_	_	_
18	gene	_	NOUN	_	Number=Sing	_	_	_	_
19	during	_	ADP	_	_	_	_	_	_
20	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
21	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	inhibiting	_	VERB	_	VerbForm=Ger	_	_	_	_
24	activation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	AP	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	site	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013146	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	12	_	NUM	_	NumType=Card	_	_	_	_
6	p40	_	NOUN	_	Number=Sing	_	_	_	_
7	transcript	_	NOUN	_	Number=Sing	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	CD40	_	PROPN	_	Number=Sing	_	_	_	_
10	ligation	_	NOUN	_	Number=Sing	_	_	_	_
11	via	_	ADP	_	_	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	Interleukin	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	12	_	NUM	_	NumType=Card	_	_	_	_
4	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	produced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
6	in	_	ADP	_	_	_	_	_	_
7	response	_	NOUN	_	Number=Sing	_	_	_	_
8	to	_	ADP	_	_	_	_	_	_
9	infection	_	NOUN	_	Number=Sing	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	bacteria	_	NOUN	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	parasites	_	NOUN	_	Number=Plur	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	to	_	ADP	_	_	_	_	_	_
16	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
17	constituents	_	NOUN	_	Number=Plur	_	_	_	_
18	such	_	ADJ	_	Degree=Pos	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	LPS	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	dendritic	_	ADJ	_	Degree=Pos	_	_	_	_
27	cells	_	NOUN	_	Number=Plur	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	and	_	CCONJ	_	_	_	_	_	_
30	also	_	ADV	_	_	_	_	_	_
31	generated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	by	_	ADP	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	interaction	_	NOUN	_	Number=Sing	_	_	_	_
35	between	_	ADP	_	_	_	_	_	_
36	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	T	_	NOUN	_	Number=Sing	_	_	_	_
38	cells	_	NOUN	_	Number=Plur	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	antigen	_	NOUN	_	Number=Sing	_	_	_	_
41	-	_	PUNCT	_	_	_	_	_	_
42	presenting	_	VERB	_	VerbForm=Ger	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	via	_	ADP	_	_	_	_	_	_
45	CD40	_	PROPN	_	Number=Sing	_	_	_	_
46	-	_	PUNCT	_	_	_	_	_	_
47	CD40	_	PROPN	_	Number=Sing	_	_	_	_
48	ligand	_	NOUN	_	Number=Sing	_	_	_	_
49	(	_	PUNCT	_	_	_	_	_	_
50	CD40L	_	NOUN	_	Number=Sing	_	_	_	_
51	)	_	PUNCT	_	_	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	So	_	ADV	_	_	_	_	_	_
2	far	_	ADV	_	Degree=Pos	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
5	analyses	_	NOUN	_	Number=Plur	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	p40	_	NOUN	_	Number=Sing	_	_	_	_
8	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
9	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
10	carried	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	out	_	ADP	_	_	_	_	_	_
12	only	_	ADV	_	_	_	_	_	_
13	using	_	VERB	_	VerbForm=Ger	_	_	_	_
14	bacterial	_	ADJ	_	Degree=Pos	_	_	_	_
15	constituents	_	NOUN	_	Number=Plur	_	_	_	_
16	such	_	ADJ	_	Degree=Pos	_	_	_	_
17	as	_	ADP	_	_	_	_	_	_
18	LPS	_	NOUN	_	Number=Sing	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	stimuli	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	present	_	ADJ	_	Degree=Pos	_	_	_	_
4	study	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
7	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
8	characterized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
11	induction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	p40	_	NOUN	_	Number=Sing	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	CD40	_	PROPN	_	Number=Sing	_	_	_	_
16	ligation	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	lymphoblastoid	_	NOUN	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	Daudi	_	PROPN	_	Number=Sing	_	_	_	_
26	,	_	PUNCT	_	_	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	acute	_	NOUN	_	Number=Sing	_	_	_	_
31	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
32	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	line	_	NOUN	_	Number=Sing	_	_	_	_
35	,	_	PUNCT	_	_	_	_	_	_
36	THP	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	agonistic	_	ADJ	_	Degree=Pos	_	_	_	_
8	monoclonal	_	ADJ	_	Degree=Pos	_	_	_	_
9	antibody	_	NOUN	_	Number=Sing	_	_	_	_
10	against	_	ADP	_	_	_	_	_	_
11	CD40	_	PROPN	_	Number=Sing	_	_	_	_
12	or	_	CCONJ	_	_	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	transfection	_	NOUN	_	Number=Sing	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	CD40L	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	vector	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
22	p40	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	enhanced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	p40	_	NOUN	_	Number=Sing	_	_	_	_
27	mRNA	_	PROPN	_	Number=Sing	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Sequence	_	NOUN	_	Number=Sing	_	_	_	_
2	analysis	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	p40	_	PROPN	_	Number=Sing	_	_	_	_
6	promoter	_	NOUN	_	Number=Sing	_	_	_	_
7	region	_	NOUN	_	Number=Sing	_	_	_	_
8	identified	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	two	_	NUM	_	NumType=Card	_	_	_	_
10	potential	_	ADJ	_	Degree=Pos	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	binding	_	NOUN	_	Number=Sing	_	_	_	_
19	sites	_	NOUN	_	Number=Plur	_	_	_	_
20	conserved	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	between	_	ADP	_	_	_	_	_	_
22	mouse	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	human	_	ADJ	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
2	mobility	_	NOUN	_	Number=Sing	_	_	_	_
3	shift	_	NOUN	_	Number=Sing	_	_	_	_
4	assay	_	NOUN	_	Number=Sing	_	_	_	_
5	revealed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	that	_	SCONJ	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	potential	_	ADJ	_	Degree=Pos	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	sequence	_	NOUN	_	Number=Sing	_	_	_	_
14	which	_	PRON	_	PronType=Rel	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	located	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
17	around	_	ADV	_	_	_	_	_	_
18	120	_	NUM	_	NumType=Card	_	_	_	_
19	bp	_	PROPN	_	Number=Sing	_	_	_	_
20	upstream	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	transcription	_	NOUN	_	Number=Sing	_	_	_	_
24	initiation	_	NOUN	_	Number=Sing	_	_	_	_
25	site	_	NOUN	_	Number=Sing	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	murine	_	NOUN	_	Number=Sing	_	_	_	_
28	and	_	CCONJ	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	p40	_	NOUN	_	Number=Sing	_	_	_	_
31	genes	_	NOUN	_	Number=Plur	_	_	_	_
32	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
34	NF	_	PROPN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
37	complex	_	NOUN	_	Number=Sing	_	_	_	_
38	with	_	ADP	_	_	_	_	_	_
39	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
40	extract	_	NOUN	_	Number=Sing	_	_	_	_
41	from	_	ADP	_	_	_	_	_	_
42	Daudi	_	PROPN	_	Number=Sing	_	_	_	_
43	cells	_	NOUN	_	Number=Plur	_	_	_	_
44	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
45	by	_	ADP	_	_	_	_	_	_
46	CD40	_	PROPN	_	Number=Sing	_	_	_	_
47	ligation	_	NOUN	_	Number=Sing	_	_	_	_
48	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	transfection	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Daudi	_	PROPN	_	Number=Sing	_	_	_	_
6	cells	_	NOUN	_	Number=Plur	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	polymerized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	NF	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
13	binding	_	NOUN	_	Number=Sing	_	_	_	_
14	sequence	_	NOUN	_	Number=Sing	_	_	_	_
15	ligated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
18	thymidine	_	NOUN	_	Number=Sing	_	_	_	_
19	kinase	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
22	acetyltransferase	_	NOUN	_	Number=Sing	_	_	_	_
23	(	_	PUNCT	_	_	_	_	_	_
24	CAT	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	reporter	_	NOUN	_	Number=Sing	_	_	_	_
27	plasmid	_	VERB	_	Number=Sing	_	_	_	_
28	greatly	_	ADV	_	_	_	_	_	_
29	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
30	CAT	_	NOUN	_	Number=Sing	_	_	_	_
31	activity	_	NOUN	_	Number=Sing	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	but	_	CCONJ	_	_	_	_	_	_
34	transfection	_	NOUN	_	Number=Sing	_	_	_	_
35	with	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	polymerized	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
38	mutated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
39	NF	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
42	binding	_	NOUN	_	Number=Sing	_	_	_	_
43	sequence	_	NOUN	_	Number=Sing	_	_	_	_
44	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
45	not	_	PART	_	_	_	_	_	_
46	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
9	binding	_	NOUN	_	Number=Sing	_	_	_	_
10	site	_	NOUN	_	Number=Sing	_	_	_	_
11	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	around	_	ADV	_	_	_	_	_	_
13	120	_	NUM	_	NumType=Card	_	_	_	_
14	bp	_	NOUN	_	Number=Sing	_	_	_	_
15	upstream	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	transcription	_	NOUN	_	Number=Sing	_	_	_	_
19	initiation	_	NOUN	_	Number=Sing	_	_	_	_
20	site	_	NOUN	_	Number=Sing	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	murine	_	NOUN	_	Number=Sing	_	_	_	_
23	and	_	CCONJ	_	_	_	_	_	_
24	human	_	ADJ	_	Degree=Pos	_	_	_	_
25	p40	_	NOUN	_	Number=Sing	_	_	_	_
26	promoter	_	NOUN	_	Number=Sing	_	_	_	_
27	regions	_	NOUN	_	Number=Plur	_	_	_	_
28	could	_	AUX	_	VerbForm=Fin	_	_	_	_
29	be	_	AUX	_	VerbForm=Inf	_	_	_	_
30	important	_	ADJ	_	Degree=Pos	_	_	_	_
31	for	_	ADP	_	_	_	_	_	_
32	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
33	p40	_	NOUN	_	Number=Sing	_	_	_	_
34	induction	_	NOUN	_	Number=Sing	_	_	_	_
35	by	_	ADP	_	_	_	_	_	_
36	CD40	_	PROPN	_	Number=Sing	_	_	_	_
37	ligation	_	NOUN	_	Number=Sing	_	_	_	_
38	via	_	ADP	_	_	_	_	_	_
39	activation	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	NF	_	PROPN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
44	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013151	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Surfactant	_	ADJ	_	Number=Sing	_	_	_	_
2	protein	_	NOUN	_	Number=Sing	_	_	_	_
3	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	activates	_	VERB	_	Number=Sing	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	THP	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	line	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	expression	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	many	_	ADJ	_	Degree=Pos	_	_	_	_
5	genes	_	NOUN	_	Number=Plur	_	_	_	_
6	for	_	ADP	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Int	_	_	_	_
8	products	_	NOUN	_	Number=Plur	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	involved	_	ADJ	_	Degree=Pos	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
13	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	regulator	_	NOUN	_	Number=Sing	_	_	_	_
19	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	)	_	PUNCT	_	_	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B.	_	PROPN	_	Number=Sing	_	_	_	_
27	Because	_	SCONJ	_	_	_	_	_	_
28	surfactant	_	ADJ	_	Number=Sing	_	_	_	_
29	protein	_	NOUN	_	Number=Sing	_	_	_	_
30	(	_	PUNCT	_	_	_	_	_	_
31	SP	_	PROPN	_	Number=Sing	_	_	_	_
32	)	_	PUNCT	_	_	_	_	_	_
33	A	_	PROPN	_	Number=Sing	_	_	_	_
34	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
35	involved	_	ADJ	_	Degree=Pos	_	_	_	_
36	in	_	ADP	_	_	_	_	_	_
37	local	_	ADJ	_	Degree=Pos	_	_	_	_
38	host	_	NOUN	_	Number=Sing	_	_	_	_
39	defense	_	NOUN	_	Number=Sing	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
42	lung	_	NOUN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	alters	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
45	immune	_	ADJ	_	Degree=Pos	_	_	_	_
46	cell	_	NOUN	_	Number=Sing	_	_	_	_
47	function	_	NOUN	_	Number=Sing	_	_	_	_
48	by	_	SCONJ	_	_	_	_	_	_
49	modulating	_	VERB	_	VerbForm=Ger	_	_	_	_
50	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
51	expression	_	NOUN	_	Number=Sing	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	proinflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
54	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
55	as	_	ADV	_	_	_	_	_	_
56	well	_	ADV	_	Degree=Pos	_	_	_	_
57	as	_	ADP	_	_	_	_	_	_
58	surface	_	NOUN	_	Number=Sing	_	_	_	_
59	proteins	_	NOUN	_	Number=Plur	_	_	_	_
60	involved	_	ADJ	_	Degree=Pos	_	_	_	_
61	in	_	ADP	_	_	_	_	_	_
62	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
63	,	_	PUNCT	_	_	_	_	_	_
64	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
65	hypothesized	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
66	that	_	SCONJ	_	_	_	_	_	_
67	SP	_	PROPN	_	Number=Sing	_	_	_	_
68	-	_	PUNCT	_	_	_	_	_	_
69	A	_	DET	_	Number=Sing	_	_	_	_
70	exerts	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
71	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
72	action	_	NOUN	_	Number=Sing	_	_	_	_
73	,	_	PUNCT	_	_	_	_	_	_
74	at	_	ADV	_	_	_	_	_	_
75	least	_	ADV	_	Degree=Sup	_	_	_	_
76	in	_	ADP	_	_	_	_	_	_
77	part	_	ADJ	_	Number=Sing	_	_	_	_
78	,	_	PUNCT	_	_	_	_	_	_
79	via	_	ADP	_	_	_	_	_	_
80	activation	_	NOUN	_	Number=Sing	_	_	_	_
81	of	_	ADP	_	_	_	_	_	_
82	NF	_	PROPN	_	Number=Sing	_	_	_	_
83	-	_	PUNCT	_	_	_	_	_	_
84	kappa	_	NOUN	_	Number=Sing	_	_	_	_
85	B	_	NOUN	_	Number=Sing	_	_	_	_
86	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	used	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	gel	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assays	_	NOUN	_	Number=Plur	_	_	_	_
6	to	_	PART	_	_	_	_	_	_
7	determine	_	VERB	_	VerbForm=Inf	_	_	_	_
8	whether	_	SCONJ	_	_	_	_	_	_
9	SP	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	THP	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
26	human	_	ADJ	_	Degree=Pos	_	_	_	_
27	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
28	cell	_	NOUN	_	Number=Sing	_	_	_	_
29	line	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	THP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	SP	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	A	_	DET	_	Number=Sing	_	_	_	_
16	doses	_	NOUN	_	Number=Plur	_	_	_	_
17	as	_	ADV	_	_	_	_	_	_
18	low	_	ADJ	_	Degree=Pos	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	1	_	NUM	_	NumType=Card	_	_	_	_
21	microgram	_	NOUN	_	Number=Sing	_	_	_	_
22	/	_	PUNCT	_	_	_	_	_	_
23	ml	_	NOUN	_	Number=Sing	_	_	_	_
24	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	within	_	ADP	_	_	_	_	_	_
26	30	_	NUM	_	NumType=Card	_	_	_	_
27	min	_	NOUN	_	Number=Plur	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	SP	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
32	treatment	_	NOUN	_	Number=Sing	_	_	_	_
33	,	_	PUNCT	_	_	_	_	_	_
34	peaked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
35	at	_	ADP	_	_	_	_	_	_
36	60	_	NUM	_	NumType=Card	_	_	_	_
37	min	_	NOUN	_	Number=Plur	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	and	_	CCONJ	_	_	_	_	_	_
40	then	_	ADV	_	PronType=Dem	_	_	_	_
41	declined	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	by	_	ADP	_	_	_	_	_	_
6	known	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	or	_	CCONJ	_	_	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	simultaneous	_	ADJ	_	Degree=Pos	_	_	_	_
16	treatment	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	with	_	ADP	_	_	_	_	_	_
21	surfactant	_	ADJ	_	Degree=Pos	_	_	_	_
22	lipids	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Moreover	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
9	blocked	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	SP	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	A	_	DET	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
15	increases	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	tumor	_	NOUN	_	Number=Sing	_	_	_	_
18	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
19	factor	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	alpha	_	NOUN	_	Number=Sing	_	_	_	_
22	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
23	levels	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	observations	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
5	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
6	by	_	ADP	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	SP	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	A	_	DET	_	Number=Sing	_	_	_	_
11	plays	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	role	_	NOUN	_	Number=Sing	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	some	_	DET	_	_	_	_	_	_
19	lung	_	NOUN	_	Number=Sing	_	_	_	_
20	conditions	_	NOUN	_	Number=Plur	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	point	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	potential	_	ADJ	_	Degree=Pos	_	_	_	_
25	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
26	measures	_	NOUN	_	Number=Plur	_	_	_	_
27	that	_	PRON	_	PronType=Rel	_	_	_	_
28	could	_	AUX	_	VerbForm=Fin	_	_	_	_
29	be	_	AUX	_	VerbForm=Inf	_	_	_	_
30	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
31	to	_	PART	_	_	_	_	_	_
32	prevent	_	VERB	_	VerbForm=Inf	_	_	_	_
33	SP	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
36	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
37	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	lung	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013152	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Inactivation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	IkappaBbeta	_	PROPN	_	Number=Sing	_	_	_	_
4	by	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	tax	_	NOUN	_	Number=Sing	_	_	_	_
7	protein	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
11	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
12	virus	_	NOUN	_	Number=Sing	_	_	_	_
13	type	_	NOUN	_	Number=Sing	_	_	_	_
14	1	_	NUM	_	NumType=Card	_	_	_	_
15	:	_	PUNCT	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	potential	_	ADJ	_	Degree=Pos	_	_	_	_
18	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
19	for	_	ADP	_	_	_	_	_	_
20	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
21	induction	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	In	_	SCONJ	_	_	_	_	_	_
2	resting	_	VERB	_	VerbForm=Ger	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	transcription	_	NOUN	_	Number=Sing	_	_	_	_
8	factor	_	NOUN	_	Number=Sing	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	sequestered	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
17	via	_	ADP	_	_	_	_	_	_
18	interactions	_	NOUN	_	Number=Plur	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	members	_	NOUN	_	Number=Plur	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
24	kappa	_	VERB	_	Number=Sing	_	_	_	_
25	B	_	PROPN	_	Number=Sing	_	_	_	_
26	family	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	including	_	VERB	_	VerbForm=Ger	_	_	_	_
31	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	IkappaBbeta	_	PROPN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	During	_	ADP	_	_	_	_	_	_
2	normal	_	ADJ	_	Degree=Pos	_	_	_	_
3	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
4	activation	_	NOUN	_	Number=Sing	_	_	_	_
5	,	_	PUNCT	_	_	_	_	_	_
6	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
7	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	rapidly	_	ADV	_	_	_	_	_	_
9	phosphorylated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	ubiquitinated	_	ADJ	_	Degree=Pos	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	degraded	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	by	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	26S	_	NOUN	_	Number=Sing	_	_	_	_
18	proteasome	_	NOUN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	thus	_	ADV	_	_	_	_	_	_
21	permitting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	release	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	functional	_	ADJ	_	Degree=Pos	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
5	transient	_	ADJ	_	Degree=Pos	_	_	_	_
6	pattern	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
9	induction	_	NOUN	_	Number=Sing	_	_	_	_
10	during	_	ADP	_	_	_	_	_	_
11	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	immune	_	ADJ	_	Degree=Pos	_	_	_	_
13	response	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	NF	_	PROPN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
18	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
19	constitutively	_	ADV	_	_	_	_	_	_
20	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	cells	_	NOUN	_	Number=Plur	_	_	_	_
23	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	Tax	_	NOUN	_	Number=Sing	_	_	_	_
26	transforming	_	NOUN	_	VerbForm=Ger	_	_	_	_
27	protein	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	human	_	ADJ	_	Degree=Pos	_	_	_	_
30	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
31	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
32	virus	_	NOUN	_	Number=Sing	_	_	_	_
33	type	_	NOUN	_	Number=Sing	_	_	_	_
34	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
35	(	_	PUNCT	_	_	_	_	_	_
36	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	1	_	NUM	_	NumType=Card	_	_	_	_
39	)	_	PUNCT	_	_	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	Tax	_	NOUN	_	Number=Sing	_	_	_	_
9	targets	_	NOUN	_	Number=Plur	_	_	_	_
10	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	ubiquitin	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	proteasome	_	NOUN	_	Degree=Pos	_	_	_	_
16	pathway	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
4	remains	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	unclear	_	ADJ	_	Degree=Pos	_	_	_	_
6	how	_	ADV	_	PronType=Int	_	_	_	_
7	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
8	viral	_	ADJ	_	Degree=Pos	_	_	_	_
9	protein	_	NOUN	_	Number=Sing	_	_	_	_
10	induces	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	persistent	_	ADJ	_	Degree=Pos	_	_	_	_
13	rather	_	ADV	_	_	_	_	_	_
14	than	_	ADP	_	_	_	_	_	_
15	transient	_	ADJ	_	Degree=Pos	_	_	_	_
16	NF	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
19	response	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	report	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	evidence	_	NOUN	_	Number=Sing	_	_	_	_
8	that	_	SCONJ	_	_	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	addition	_	NOUN	_	Number=Sing	_	_	_	_
11	to	_	SCONJ	_	_	_	_	_	_
12	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	on	_	ADP	_	_	_	_	_	_
14	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	Tax	_	NOUN	_	Number=Sing	_	_	_	_
17	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	turnover	_	NOUN	_	Number=Sing	_	_	_	_
20	Of	_	ADP	_	_	_	_	_	_
21	IkappaBbeta	_	PROPN	_	Number=Sing	_	_	_	_
22	via	_	ADP	_	_	_	_	_	_
23	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
24	related	_	ADJ	_	Degree=Pos	_	_	_	_
25	targeting	_	NOUN	_	Number=Sing	_	_	_	_
26	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Like	_	ADP	_	_	_	_	_	_
2	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	Tax	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	mediated	_	VERB	_	Degree=Pos	_	_	_	_
7	breakdown	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	IkappaBbeta	_	PROPN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	transfected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
12	T	_	NOUN	_	Number=Sing	_	_	_	_
13	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
14	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	blocked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	either	_	CCONJ	_	_	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	cell	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	permeable	_	ADJ	_	Degree=Pos	_	_	_	_
21	proteasome	_	ADJ	_	Degree=Pos	_	_	_	_
22	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
23	or	_	CCONJ	_	_	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	mutation	_	NOUN	_	Number=Sing	_	_	_	_
26	Of	_	ADP	_	_	_	_	_	_
27	IkappaBbeta	_	PROPN	_	Number=Sing	_	_	_	_
28	at	_	ADP	_	_	_	_	_	_
29	two	_	NUM	_	NumType=Card	_	_	_	_
30	serine	_	NOUN	_	Number=Sing	_	_	_	_
31	residues	_	NOUN	_	Number=Plur	_	_	_	_
32	present	_	VERB	_	Degree=Pos	_	_	_	_
33	within	_	ADP	_	_	_	_	_	_
34	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
35	N	_	NOUN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	terminal	_	NOUN	_	Number=Sing	_	_	_	_
38	region	_	NOUN	_	Number=Sing	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Despite	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	dual	_	ADJ	_	Degree=Pos	_	_	_	_
4	specificity	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	HTLV	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	1	_	NUM	_	NumType=Card	_	_	_	_
9	Tax	_	NOUN	_	Number=Sing	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	IkappaBbeta	_	PROPN	_	Number=Sing	_	_	_	_
14	at	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	protein	_	NOUN	_	Number=Sing	_	_	_	_
17	level	_	NOUN	_	Number=Sing	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	Tax	_	NOUN	_	Number=Sing	_	_	_	_
20	selectively	_	ADV	_	_	_	_	_	_
21	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
22	NF	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
25	-	_	PUNCT	_	_	_	_	_	_
26	directed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
27	transcription	_	NOUN	_	Number=Sing	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	IkappaBalpha	_	PROPN	_	Number=Sing	_	_	_	_
31	gene	_	NOUN	_	Number=Sing	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	Consequently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	IkappaBbeta	_	PROPN	_	Number=Sing	_	_	_	_
4	protein	_	NOUN	_	Number=Sing	_	_	_	_
5	expression	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	chronically	_	ADV	_	_	_	_	_	_
8	downregulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	HTLV	_	PROPN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1-infected	_	VERB	_	Degree=Pos	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	findings	_	NOUN	_	Number=Plur	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	IkappaBbeta	_	PROPN	_	Number=Sing	_	_	_	_
5	provide	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
7	potential	_	ADJ	_	Degree=Pos	_	_	_	_
8	mechanism	_	NOUN	_	Number=Sing	_	_	_	_
9	for	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
12	activation	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	Tax	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013156	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	role	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
11	gene	_	NOUN	_	Number=Sing	_	_	_	_
12	regulation	_	NOUN	_	Number=Sing	_	_	_	_
13	.	_	PUNCT	_	_	_	_	_	_

1	Transcription	_	NOUN	_	Number=Sing	_	_	_	_
2	factors	_	NOUN	_	Number=Plur	_	_	_	_
3	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	DNA	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	VERB	_	Number=Sing	_	_	_	_
7	proteins	_	NOUN	_	Number=Plur	_	_	_	_
8	that	_	PRON	_	PronType=Rel	_	_	_	_
9	regulate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	gene	_	NOUN	_	Number=Sing	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	.	_	PUNCT	_	_	_	_	_	_

1	Nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
2	factor	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	kappa	_	NOUN	_	Number=Sing	_	_	_	_
10	B	_	NOUN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	critical	_	ADJ	_	Degree=Pos	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	maximal	_	ADJ	_	Degree=Pos	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	many	_	ADJ	_	Degree=Pos	_	_	_	_
22	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
25	involved	_	ADJ	_	Degree=Pos	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	pathogenesis	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
31	diseases	_	NOUN	_	Number=Plur	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	such	_	ADJ	_	Degree=Pos	_	_	_	_
34	as	_	ADP	_	_	_	_	_	_
35	adult	_	NOUN	_	Number=Sing	_	_	_	_
36	respiratory	_	ADJ	_	Number=Sing	_	_	_	_
37	distress	_	NOUN	_	Number=Sing	_	_	_	_
38	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
39	(	_	PUNCT	_	_	_	_	_	_
40	ARDS	_	NOUN	_	Number=Sing	_	_	_	_
41	)	_	PUNCT	_	_	_	_	_	_
42	and	_	CCONJ	_	_	_	_	_	_
43	sepsis	_	NOUN	_	Number=Sing	_	_	_	_
44	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	and	_	CCONJ	_	_	_	_	_	_
3	regulation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	NOUN	_	Number=Sing	_	_	_	_
8	B	_	NOUN	_	Number=Sing	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	tightly	_	ADV	_	_	_	_	_	_
11	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	group	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	inhibitory	_	NOUN	_	Number=Sing	_	_	_	_
17	proteins	_	NOUN	_	Number=Plur	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
20	kappa	_	VERB	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	_	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	that	_	DET	_	_	_	_	_	_
24	sequester	_	VERB	_	Number=Sing	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	cytoplasm	_	NOUN	_	Number=Sing	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	immune	_	ADJ	_	Number=Sing	_	_	_	_
34	/	_	PUNCT	_	_	_	_	_	_
35	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
36	effector	_	NOUN	_	Number=Sing	_	_	_	_
37	cells	_	NOUN	_	Number=Plur	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	signaled	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	phosphorylation	_	NOUN	_	Number=Sing	_	_	_	_
9	,	_	PUNCT	_	_	_	_	_	_
10	ubiquitination	_	NOUN	_	Number=Sing	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	proteolysis	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	I	_	PRON	_	Case=Nom|Number=Sing|Person=1|PronType=Prs	_	_	_	_
16	kappa	_	PROPN	_	Number=Sing	_	_	_	_
17	B.	_	PROPN	_	Number=Sing	_	_	_	_
18	Liberated	_	PROPN	_	Number=Sing	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	PROPN	_	Number=Sing	_	_	_	_

1	B	_	PROPN	_	Number=Sing	_	_	_	_
2	migrates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	nucleus	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	where	_	ADV	_	PronType=Rel	_	_	_	_
8	it	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
9	binds	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	specific	_	ADJ	_	Degree=Pos	_	_	_	_
12	promoter	_	NOUN	_	Number=Sing	_	_	_	_
13	sites	_	NOUN	_	Number=Plur	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	gene	_	NOUN	_	Number=Sing	_	_	_	_
17	transcription	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	activation	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	NF	_	PROPN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	kappa	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	initiates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	both	_	CCONJ	_	_	_	_	_	_
10	extracellular	_	ADJ	_	Degree=Pos	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	intracellular	_	ADJ	_	Degree=Pos	_	_	_	_
13	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
14	events	_	NOUN	_	Number=Plur	_	_	_	_
15	that	_	DET	_	PronType=Rel	_	_	_	_
16	result	_	VERB	_	Number=Sing	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	autoregulation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	inflammatory	_	ADJ	_	Degree=Pos	_	_	_	_
22	cascade	_	NOUN	_	Number=Sing	_	_	_	_
23	through	_	ADP	_	_	_	_	_	_
24	modulation	_	NOUN	_	Number=Sing	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	NF	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	kappa	_	NOUN	_	Number=Sing	_	_	_	_
29	B	_	NOUN	_	Number=Sing	_	_	_	_
30	activation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	Recently	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	activation	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	NF	_	PROPN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	kappa	_	PROPN	_	Number=Sing	_	_	_	_
8	B	_	PROPN	_	Number=Sing	_	_	_	_
9	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
11	linked	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	ARDS	_	PROPN	_	Number=Sing	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
17	shown	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	be	_	AUX	_	VerbForm=Inf	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	critical	_	ADJ	_	Degree=Pos	_	_	_	_
22	proximal	_	ADJ	_	Degree=Pos	_	_	_	_
23	step	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	initiation	_	NOUN	_	Number=Sing	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	neutrophilic	_	ADJ	_	Degree=Pos	_	_	_	_
29	inflammation	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	animal	_	NOUN	_	Number=Sing	_	_	_	_
32	models	_	NOUN	_	Number=Plur	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Activation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	NF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	kappa	_	NOUN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	can	_	AUX	_	VerbForm=Fin	_	_	_	_
8	be	_	AUX	_	VerbForm=Inf	_	_	_	_
9	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	vivo	_	NOUN	_	Number=Sing	_	_	_	_
12	by	_	ADP	_	_	_	_	_	_
13	treatment	_	NOUN	_	Number=Sing	_	_	_	_
14	with	_	ADP	_	_	_	_	_	_
15	antioxidants	_	NOUN	_	Number=Plur	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	corticosteroids	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	induction	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	endotoxin	_	NOUN	_	Degree=Pos	_	_	_	_
24	tolerance	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Identification	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	more	_	ADJ	_	_	_	_	_	_
4	specific	_	ADJ	_	Degree=Pos	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	efficacious	_	ADJ	_	Degree=Pos	_	_	_	_
7	inhibitors	_	NOUN	_	Number=Plur	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	activation	_	NOUN	_	Number=Sing	_	_	_	_
14	might	_	AUX	_	VerbForm=Fin	_	_	_	_
15	prove	_	VERB	_	VerbForm=Inf	_	_	_	_
16	beneficial	_	ADJ	_	Degree=Pos	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	treatment	_	NOUN	_	Number=Sing	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
24	inflammatory	_	ADJ	_	Number=Sing	_	_	_	_
25	diseases	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013159	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Superantigens	_	NOUN	_	Number=Plur	_	_	_	_
2	activate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	HIV	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	Binding	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	superantigens	_	NOUN	_	Number=Plur	_	_	_	_
4	to	_	ADP	_	_	_	_	_	_
5	MHC	_	PROPN	_	Number=Sing	_	_	_	_
6	class	_	NOUN	_	Number=Sing	_	_	_	_
7	II	_	NUM	_	NumType=Card	_	_	_	_
8	molecules	_	NOUN	_	Number=Plur	_	_	_	_
9	results	_	NOUN	_	Number=Plur	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	transduction	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
14	signals	_	NOUN	_	Number=Plur	_	_	_	_
15	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
16	to	_	ADP	_	_	_	_	_	_
17	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	activation	_	NOUN	_	Number=Sing	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	gene	_	NOUN	_	Number=Sing	_	_	_	_
21	expression	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	staphylococcal	_	ADJ	_	Degree=Pos	_	_	_	_
6	superantigens	_	NOUN	_	Number=Plur	_	_	_	_
7	toxic	_	ADJ	_	Degree=Pos	_	_	_	_
8	shock	_	NOUN	_	Number=Sing	_	_	_	_
9	syndrome	_	NOUN	_	Number=Sing	_	_	_	_
10	toxin	_	NOUN	_	Number=Sing	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	1	_	NUM	_	NumType=Card	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	TSST	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	staphylococcal	_	ADJ	_	Degree=Pos	_	_	_	_
20	enterotoxin	_	NOUN	_	Number=Sing	_	_	_	_
21	A	_	PROPN	_	Number=Sing	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	SEA	_	NOUN	_	Number=Sing	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
26	HIV	_	NOUN	_	Number=Sing	_	_	_	_
27	-	_	PUNCT	_	_	_	_	_	_
28	1	_	NUM	_	NumType=Card	_	_	_	_
29	-	_	PUNCT	_	_	_	_	_	_
30	LTR	_	NOUN	_	Number=Sing	_	_	_	_
31	-	_	PUNCT	_	_	_	_	_	_
32	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
33	transcription	_	NOUN	_	Number=Sing	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	chloramphenicol	_	ADJ	_	Number=Sing	_	_	_	_
36	acetyl	_	NOUN	_	Number=Sing	_	_	_	_
37	transferase	_	NOUN	_	Number=Sing	_	_	_	_
38	in	_	ADP	_	_	_	_	_	_
39	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
40	human	_	ADJ	_	Degree=Pos	_	_	_	_
41	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
42	cell	_	NOUN	_	Number=Sing	_	_	_	_
43	line	_	NOUN	_	Number=Sing	_	_	_	_
44	THP	_	NOUN	_	Number=Sing	_	_	_	_
45	-	_	PUNCT	_	_	_	_	_	_
46	1	_	NUM	_	NumType=Card	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_
48	Induction	_	NOUN	_	Number=Sing	_	_	_	_
49	of	_	ADP	_	_	_	_	_	_
50	HIV	_	NOUN	_	Number=Sing	_	_	_	_
51	-	_	PUNCT	_	_	_	_	_	_
52	1-LTR	_	NOUN	_	NumType=Card	_	_	_	_
53	-	_	PUNCT	_	_	_	_	_	_
54	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
55	transcription	_	NOUN	_	Number=Sing	_	_	_	_
56	in	_	ADP	_	_	_	_	_	_
57	THP	_	NOUN	_	Number=Sing	_	_	_	_
58	-	_	PUNCT	_	_	_	_	_	_
59	1	_	NUM	_	NumType=Card	_	_	_	_
60	cells	_	NOUN	_	Number=Plur	_	_	_	_
61	by	_	ADP	_	_	_	_	_	_
62	superantigens	_	NOUN	_	Number=Plur	_	_	_	_
63	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
64	associated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
65	with	_	ADP	_	_	_	_	_	_
66	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
67	induction	_	NOUN	_	Number=Sing	_	_	_	_
68	of	_	ADP	_	_	_	_	_	_
69	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
70	factor	_	NOUN	_	Number=Sing	_	_	_	_
71	-	_	PUNCT	_	_	_	_	_	_
72	kappa	_	NOUN	_	Number=Sing	_	_	_	_
73	B	_	NOUN	_	Number=Sing	_	_	_	_
74	DNA	_	NOUN	_	Number=Sing	_	_	_	_
75	-	_	PUNCT	_	_	_	_	_	_
76	binding	_	NOUN	_	Number=Sing	_	_	_	_
77	activity	_	NOUN	_	Number=Sing	_	_	_	_
78	.	_	PUNCT	_	_	_	_	_	_

1	Superantigens	_	NOUN	_	Number=Plur	_	_	_	_
2	also	_	ADV	_	_	_	_	_	_
3	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	viral	_	ADJ	_	Degree=Pos	_	_	_	_
5	protein	_	NOUN	_	Number=Sing	_	_	_	_
6	secretion	_	NOUN	_	Number=Sing	_	_	_	_
7	from	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
12	colony	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
15	factor	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	pretreated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	chronically	_	ADV	_	_	_	_	_	_
19	infected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
22	cell	_	NOUN	_	Number=Sing	_	_	_	_
23	line	_	NOUN	_	Number=Sing	_	_	_	_
24	U1	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	HIV	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	gene	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	monocytic	_	ADJ	_	Degree=Pos	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	superantigens	_	NOUN	_	Number=Plur	_	_	_	_
13	occurred	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	via	_	ADP	_	_	_	_	_	_
15	tumor	_	NOUN	_	Number=Sing	_	_	_	_
16	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
17	factor	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	alpha	_	NOUN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	independent	_	ADJ	_	Degree=Pos	_	_	_	_
25	mechanisms	_	NOUN	_	Number=Plur	_	_	_	_
26	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	superantigens	_	NOUN	_	Number=Plur	_	_	_	_
6	and	_	CCONJ	_	_	_	_	_	_
7	other	_	ADJ	_	Degree=Pos	_	_	_	_
8	MHC	_	PROPN	_	Number=Sing	_	_	_	_
9	class	_	NOUN	_	Number=Sing	_	_	_	_
10	II	_	NUM	_	NumType=Card	_	_	_	_
11	ligands	_	NOUN	_	Number=Plur	_	_	_	_
12	may	_	AUX	_	VerbForm=Fin	_	_	_	_
13	activate	_	VERB	_	VerbForm=Inf	_	_	_	_
14	HIV	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	gene	_	NOUN	_	Number=Sing	_	_	_	_
18	expression	_	NOUN	_	Number=Sing	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
21	/	_	PUNCT	_	_	_	_	_	_
22	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013160	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Glucocorticoid	_	ADJ	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	leukemic	_	ADJ	_	Degree=Pos	_	_	_	_
8	cells	_	NOUN	_	Number=Plur	_	_	_	_
9	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	caused	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	by	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	repressive	_	ADJ	_	Degree=Pos	_	_	_	_
14	function	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	glucocorticoid	_	NOUN	_	Number=Sing	_	_	_	_
18	receptor	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Induction	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	which	_	PRON	_	PronType=Rel	_	_	_	_
8	may	_	AUX	_	VerbForm=Fin	_	_	_	_
9	account	_	VERB	_	VerbForm=Inf	_	_	_	_
10	for	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
13	effects	_	NOUN	_	Number=Plur	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	glucocorticoids	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	various	_	ADJ	_	Degree=Pos	_	_	_	_
18	diseases	_	NOUN	_	Number=Plur	_	_	_	_
19	including	_	VERB	_	VerbForm=Ger	_	_	_	_
20	leukemia	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	depends	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
23	on	_	ADP	_	_	_	_	_	_
24	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
25	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
26	receptor	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	events	_	NOUN	_	Number=Plur	_	_	_	_
5	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
9	receptor	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	lysis	_	NOUN	_	Number=Sing	_	_	_	_
13	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
14	not	_	PART	_	_	_	_	_	_
15	understood	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	prevailing	_	ADJ	_	Degree=Pos	_	_	_	_
3	hypothesis	_	NOUN	_	Number=Sing	_	_	_	_
4	postulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	induction	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	so	_	ADV	_	_	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	called	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	'	_	PUNCT	_	_	_	_	_	_
11	lysis	_	ADJ	_	Number=Sing	_	_	_	_
12	genes	_	NOUN	_	Number=Plur	_	_	_	_
13	'	_	PUNCT	_	_	_	_	_	_
14	by	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	receptor	_	NOUN	_	Number=Sing	_	_	_	_
18	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	this	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
3	study	_	NOUN	_	Number=Sing	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
6	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
9	activation	_	NOUN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	deficient	_	ADJ	_	Degree=Pos	_	_	_	_
12	glucocorticoid	_	NOUN	_	Degree=Pos	_	_	_	_
13	receptor	_	NOUN	_	Number=Sing	_	_	_	_
14	mutant	_	NOUN	_	Number=Sing	_	_	_	_
15	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
16	as	_	ADV	_	_	_	_	_	_
17	effective	_	ADJ	_	Degree=Pos	_	_	_	_
18	as	_	ADP	_	_	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	wild	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	type	_	NOUN	_	Number=Sing	_	_	_	_
23	receptor	_	NOUN	_	Number=Sing	_	_	_	_
24	in	_	ADP	_	_	_	_	_	_
25	repression	_	NOUN	_	Number=Sing	_	_	_	_
26	of	_	ADP	_	_	_	_	_	_
27	AP	_	NOUN	_	Number=Sing	_	_	_	_
28	-	_	PUNCT	_	_	_	_	_	_
29	1	_	NUM	_	NumType=Card	_	_	_	_
30	activity	_	NOUN	_	Number=Sing	_	_	_	_
31	,	_	PUNCT	_	_	_	_	_	_
32	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
33	of	_	ADP	_	_	_	_	_	_
34	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
35	-	_	PUNCT	_	_	_	_	_	_
36	2	_	NUM	_	NumType=Card	_	_	_	_
37	production	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
40	of	_	ADP	_	_	_	_	_	_
41	c-myc	_	ADJ	_	Degree=Pos	_	_	_	_
42	expression	_	NOUN	_	Number=Sing	_	_	_	_
43	and	_	CCONJ	_	_	_	_	_	_
44	induction	_	NOUN	_	Number=Sing	_	_	_	_
45	of	_	ADP	_	_	_	_	_	_
46	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
4	show	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
5	that	_	SCONJ	_	_	_	_	_	_
6	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
7	acid	_	NOUN	_	Number=Sing	_	_	_	_
8	can	_	AUX	_	VerbForm=Fin	_	_	_	_
9	also	_	ADV	_	_	_	_	_	_
10	induce	_	VERB	_	VerbForm=Inf	_	_	_	_
11	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
14	cells	_	NOUN	_	Number=Plur	_	_	_	_
15	through	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	retinoic	_	ADJ	_	Degree=Pos	_	_	_	_
18	acid	_	NOUN	_	Number=Sing	_	_	_	_
19	receptor	_	NOUN	_	Number=Sing	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	whose	_	PRON	_	Poss=Yes|PronType=Int	_	_	_	_
22	repressive	_	ADJ	_	Degree=Pos	_	_	_	_
23	functions	_	NOUN	_	Number=Plur	_	_	_	_
24	but	_	CCONJ	_	_	_	_	_	_
25	not	_	PART	_	_	_	_	_	_
26	target	_	VERB	_	VerbForm=Inf	_	_	_	_
27	site	_	NOUN	_	Number=Sing	_	_	_	_
28	specificity	_	NOUN	_	Number=Sing	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
31	similar	_	ADJ	_	Degree=Pos	_	_	_	_
32	to	_	ADP	_	_	_	_	_	_
33	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
34	of	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
37	receptor	_	NOUN	_	Number=Sing	_	_	_	_
38	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	primary	_	ADJ	_	Degree=Pos	_	_	_	_
5	effect	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
8	receptor	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	glucocorticoid	_	ADJ	_	Degree=Pos	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	mediated	_	ADJ	_	Degree=Pos	_	_	_	_
13	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
14	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
15	with	_	ADP	_	_	_	_	_	_
16	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
17	repression	_	NOUN	_	Number=Sing	_	_	_	_
18	rather	_	ADV	_	_	_	_	_	_
19	than	_	ADP	_	_	_	_	_	_
20	activation	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	could	_	AUX	_	VerbForm=Fin	_	_	_	_
23	be	_	AUX	_	VerbForm=Inf	_	_	_	_
24	mediated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	by	_	ADP	_	_	_	_	_	_
26	interference	_	NOUN	_	Number=Sing	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	other	_	ADJ	_	Degree=Pos	_	_	_	_
29	transcription	_	NOUN	_	Number=Sing	_	_	_	_
30	factors	_	NOUN	_	Number=Plur	_	_	_	_
31	required	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	for	_	ADP	_	_	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	survival	_	NOUN	_	Number=Sing	_	_	_	_
35	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013172	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	OBF	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	,	_	PUNCT	_	_	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	novel	_	NOUN	_	Number=Sing	_	_	_	_
7	B	_	NOUN	_	Number=Sing	_	_	_	_
8	cell	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	specific	_	ADJ	_	Degree=Pos	_	_	_	_
11	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
12	that	_	PRON	_	PronType=Rel	_	_	_	_
13	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
14	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
15	promoter	_	NOUN	_	Number=Sing	_	_	_	_
16	activity	_	NOUN	_	Number=Sing	_	_	_	_
17	through	_	ADP	_	_	_	_	_	_
18	association	_	NOUN	_	Number=Sing	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	octamer	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	binding	_	VERB	_	Number=Sing	_	_	_	_
23	proteins	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
3	and	_	CCONJ	_	_	_	_	_	_
4	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
5	studies	_	NOUN	_	Number=Plur	_	_	_	_
6	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
7	that	_	SCONJ	_	_	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	addition	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	octamer	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	binding	_	NOUN	_	Number=Sing	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	Oct	_	PROPN	_	Number=Sing	_	_	_	_
17	-	_	PUNCT	_	_	_	_	_	_
18	1	_	NUM	_	NumType=Card	_	_	_	_
19	and	_	CCONJ	_	_	_	_	_	_
20	Oct	_	PROPN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	2	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	other	_	ADJ	_	Degree=Pos	_	_	_	_
25	B	_	ADJ	_	Number=Sing	_	_	_	_
26	cell	_	NOUN	_	Number=Sing	_	_	_	_
27	components	_	NOUN	_	Number=Plur	_	_	_	_
28	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	required	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
30	for	_	ADP	_	_	_	_	_	_
31	lymphoid	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	restricted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	,	_	PUNCT	_	_	_	_	_	_
35	octamer	_	ADJ	_	Number=Sing	_	_	_	_
36	site	_	NOUN	_	Number=Sing	_	_	_	_
37	-	_	PUNCT	_	_	_	_	_	_
38	mediated	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
39	immunoglobulin	_	ADJ	_	Degree=Pos	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	promoter	_	NOUN	_	Number=Sing	_	_	_	_
42	activity	_	NOUN	_	Number=Sing	_	_	_	_
43	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
4	screen	_	NOUN	_	Number=Sing	_	_	_	_
5	in	_	ADP	_	_	_	_	_	_
6	yeast	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
9	have	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	isolated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	B	_	PROPN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	-	_	PUNCT	_	_	_	_	_	_
14	derived	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	cDNAs	_	NOUN	_	Number=Plur	_	_	_	_
16	encoding	_	VERB	_	VerbForm=Ger	_	_	_	_
17	Oct	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	1	_	NUM	_	NumType=Card	_	_	_	_
22	(	_	PUNCT	_	_	_	_	_	_
23	OBF	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	1	_	NUM	_	NumType=Card	_	_	_	_
26	)	_	PUNCT	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
29	novel	_	NOUN	_	Number=Sing	_	_	_	_
30	protein	_	NOUN	_	Number=Sing	_	_	_	_
31	that	_	PRON	_	PronType=Rel	_	_	_	_
32	specifically	_	ADV	_	_	_	_	_	_
33	associates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
34	with	_	ADP	_	_	_	_	_	_
35	Oct	_	PROPN	_	Number=Sing	_	_	_	_
36	-	_	PUNCT	_	_	_	_	_	_
37	1	_	NUM	_	NumType=Card	_	_	_	_
38	and	_	CCONJ	_	_	_	_	_	_
39	Oct	_	PROPN	_	Number=Sing	_	_	_	_
40	-	_	PUNCT	_	_	_	_	_	_
41	2	_	NUM	_	NumType=Card	_	_	_	_
42	.	_	PUNCT	_	_	_	_	_	_

1	Biochemical	_	ADJ	_	Degree=Pos	_	_	_	_
2	studies	_	NOUN	_	Number=Plur	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	OBF	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
9	no	_	DET	_	_	_	_	_	_
10	intrinsic	_	ADJ	_	Degree=Pos	_	_	_	_
11	DNA	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	recognizes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	POU	_	NOUN	_	Number=Sing	_	_	_	_
19	domains	_	NOUN	_	Number=Plur	_	_	_	_
20	of	_	ADP	_	_	_	_	_	_
21	Oct	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	PUNCT	_	_	_	_	_	_
23	1	_	NUM	_	NumType=Card	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	Oct	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	2	_	NUM	_	NumType=Card	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	but	_	CCONJ	_	_	_	_	_	_
30	not	_	ADV	_	_	_	_	_	_
31	those	_	PRON	_	Number=Plur|PronType=Dem	_	_	_	_
32	of	_	ADP	_	_	_	_	_	_
33	Oct	_	PROPN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	4	_	NUM	_	NumType=Card	_	_	_	_
36	and	_	CCONJ	_	_	_	_	_	_
37	Oct	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	SYM	_	_	_	_	_	_
39	6	_	NUM	_	NumType=Card	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	OBF	_	PROPN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	1	_	NUM	_	NumType=Card	_	_	_	_
5	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	expressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	highly	_	ADV	_	_	_	_	_	_
11	cell	_	ADJ	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	manner	_	NOUN	_	Number=Sing	_	_	_	_
15	,	_	PUNCT	_	_	_	_	_	_
16	being	_	AUX	_	VerbForm=Ger	_	_	_	_
17	most	_	ADV	_	_	_	_	_	_
18	abundant	_	ADJ	_	Degree=Pos	_	_	_	_
19	in	_	ADP	_	_	_	_	_	_
20	B	_	ADJ	_	Degree=Pos	_	_	_	_
21	cells	_	NOUN	_	Number=Plur	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	essentially	_	ADV	_	_	_	_	_	_
24	absent	_	VERB	_	Degree=Pos	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	most	_	ADJ	_	Degree=Sup	_	_	_	_
27	of	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	other	_	ADJ	_	Degree=Pos	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	or	_	CCONJ	_	_	_	_	_	_
32	tissues	_	NOUN	_	Number=Plur	_	_	_	_
33	tested	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	expression	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	OBF	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	1	_	NUM	_	NumType=Card	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	HeLa	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	selectively	_	ADV	_	_	_	_	_	_
12	stimulates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
17	natural	_	ADJ	_	Degree=Pos	_	_	_	_
18	immunoglobulin	_	ADJ	_	Number=Sing	_	_	_	_
19	promoter	_	NOUN	_	Number=Sing	_	_	_	_
20	in	_	ADP	_	_	_	_	_	_
21	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	octamer	_	ADJ	_	Number=Sing	_	_	_	_
23	site	_	NOUN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	manner	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Thus	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	OBF	_	PROPN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	1	_	NUM	_	NumType=Card	_	_	_	_
6	has	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	all	_	DET	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	properties	_	NOUN	_	Number=Plur	_	_	_	_
10	expected	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	for	_	ADP	_	_	_	_	_	_
12	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
13	B	_	NUM	_	Degree=Pos	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	transcriptional	_	ADJ	_	Degree=Pos	_	_	_	_
18	coactivator	_	NOUN	_	Number=Sing	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013173	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	T	_	PROPN	_	Number=Sing	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	from	_	ADP	_	_	_	_	_	_
4	renal	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
7	patients	_	NOUN	_	Number=Plur	_	_	_	_
8	exhibit	_	VERB	_	VerbForm=Inf	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	abnormal	_	ADJ	_	Degree=Pos	_	_	_	_
11	pattern	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	kappa	_	NOUN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	specific	_	ADJ	_	Degree=Pos	_	_	_	_
17	DNA	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	binding	_	NOUN	_	Number=Sing	_	_	_	_
20	activity	_	NOUN	_	Number=Sing	_	_	_	_
21	:	_	PUNCT	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	preliminary	_	ADJ	_	Degree=Pos	_	_	_	_
24	report	_	NOUN	_	Number=Sing	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Recent	_	ADJ	_	Degree=Pos	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	poor	_	ADJ	_	Degree=Pos	_	_	_	_
7	induction	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	T-cell	_	ADJ	_	Number=Sing	_	_	_	_
11	response	_	NOUN	_	Number=Sing	_	_	_	_
12	to	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	renal	_	ADJ	_	Degree=Pos	_	_	_	_
15	cell	_	NOUN	_	Number=Sing	_	_	_	_
16	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	RCC	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	may	_	AUX	_	VerbForm=Fin	_	_	_	_
21	be	_	AUX	_	VerbForm=Inf	_	_	_	_
22	related	_	ADJ	_	Degree=Pos	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	alterations	_	NOUN	_	Number=Plur	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	signal	_	ADJ	_	Number=Sing	_	_	_	_
27	transduction	_	NOUN	_	Number=Sing	_	_	_	_
28	pathways	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	We	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
2	report	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
3	that	_	SCONJ	_	_	_	_	_	_
4	T	_	PROPN	_	Number=Sing	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	from	_	ADP	_	_	_	_	_	_
7	RCC	_	PROPN	_	Number=Sing	_	_	_	_
8	patients	_	NOUN	_	Number=Plur	_	_	_	_
9	have	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	two	_	NUM	_	NumType=Card	_	_	_	_
11	alterations	_	NOUN	_	Number=Plur	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	kappa	_	PROPN	_	Number=Sing	_	_	_	_
14	B	_	NOUN	_	Number=Sing	_	_	_	_
15	motif	_	NOUN	_	Number=Sing	_	_	_	_
16	-	_	PUNCT	_	_	_	_	_	_
17	specific	_	ADJ	_	Degree=Pos	_	_	_	_
18	DNA	_	NOUN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	binding	_	NOUN	_	Number=Sing	_	_	_	_
21	activity	_	NOUN	_	Number=Sing	_	_	_	_
22	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	first	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	alteration	_	NOUN	_	Number=Sing	_	_	_	_
4	involves	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	constitutive	_	ADJ	_	Degree=Pos	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	substantial	_	ADJ	_	Degree=Pos	_	_	_	_
10	kappa	_	NOUN	_	Number=Sing	_	_	_	_
11	B	_	NOUN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	binding	_	VERB	_	Number=Sing	_	_	_	_
14	activity	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
17	extracts	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	which	_	PRON	_	PronType=Rel	_	_	_	_
20	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
21	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	electrophoretic	_	ADJ	_	Degree=Pos	_	_	_	_
25	mobility	_	NOUN	_	Number=Sing	_	_	_	_
26	shift	_	NOUN	_	Number=Sing	_	_	_	_
27	assay	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	magnitude	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	kappa	_	NOUN	_	Number=Sing	_	_	_	_
5	B	_	NOUN	_	Number=Sing	_	_	_	_
6	activity	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
9	patient	_	NOUN	_	Number=Sing	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cells	_	NOUN	_	Number=Plur	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	similar	_	ADJ	_	Degree=Pos	_	_	_	_
14	to	_	ADP	_	_	_	_	_	_
15	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
16	observed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	T	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	from	_	ADP	_	_	_	_	_	_
21	normal	_	ADJ	_	Degree=Pos	_	_	_	_
22	individuals	_	NOUN	_	Number=Plur	_	_	_	_
23	that	_	PRON	_	PronType=Rel	_	_	_	_
24	had	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
25	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
26	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
27	in	_	ADP	_	_	_	_	_	_
28	vitro	_	NOUN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	On	_	ADP	_	_	_	_	_	_
2	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
3	basis	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	Western	_	ADJ	_	Degree=Pos	_	_	_	_
6	blotting	_	NOUN	_	Number=Sing	_	_	_	_
7	experiments	_	NOUN	_	Number=Plur	_	_	_	_
8	using	_	VERB	_	VerbForm=Ger	_	_	_	_
9	antibodies	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	kappa	_	PROPN	_	Number=Sing	_	_	_	_
12	B	_	PROPN	_	Number=Sing	_	_	_	_
13	/	_	PUNCT	_	_	_	_	_	_
14	Rel	_	PROPN	_	Number=Sing	_	_	_	_
15	family	_	NOUN	_	Number=Sing	_	_	_	_
16	proteins	_	NOUN	_	Number=Plur	_	_	_	_
17	,	_	PUNCT	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	binding	_	NOUN	_	Number=Sing	_	_	_	_
23	activity	_	NOUN	_	Number=Sing	_	_	_	_
24	constitutively	_	ADV	_	_	_	_	_	_
25	expressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
26	in	_	ADP	_	_	_	_	_	_
27	T	_	PROPN	_	Number=Sing	_	_	_	_
28	cells	_	NOUN	_	Number=Plur	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	RCC	_	PROPN	_	Number=Sing	_	_	_	_
31	patients	_	NOUN	_	Number=Plur	_	_	_	_
32	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
33	composed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	mostly	_	ADV	_	_	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
37	NF	_	PROPN	_	Number=Sing	_	_	_	_
38	-	_	PUNCT	_	_	_	_	_	_
39	kappa	_	NOUN	_	Number=Sing	_	_	_	_
40	B1	_	NOUN	_	Number=Sing	_	_	_	_
41	(	_	PUNCT	_	_	_	_	_	_
42	p50	_	NOUN	_	Number=Sing	_	_	_	_
43	)	_	PUNCT	_	_	_	_	_	_
44	subunit	_	NOUN	_	Number=Sing	_	_	_	_
45	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	second	_	ADJ	_	Degree=Pos|NumType=Ord	_	_	_	_
3	abnormality	_	NOUN	_	Number=Sing	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	kappa	_	PROPN	_	Number=Sing	_	_	_	_
6	B	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	binding	_	VERB	_	Number=Sing	_	_	_	_
9	activity	_	NOUN	_	Number=Sing	_	_	_	_
10	in	_	ADP	_	_	_	_	_	_
11	T	_	PROPN	_	Number=Sing	_	_	_	_
12	cells	_	NOUN	_	Number=Plur	_	_	_	_
13	from	_	ADP	_	_	_	_	_	_
14	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
15	patients	_	NOUN	_	Number=Plur	_	_	_	_
16	is	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
17	that	_	SCONJ	_	_	_	_	_	_
18	RelA	_	PROPN	_	Number=Sing	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
21	member	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
24	Rel	_	PROPN	_	Number=Sing	_	_	_	_
25	homology	_	NOUN	_	Number=Sing	_	_	_	_
26	family	_	NOUN	_	Number=Sing	_	_	_	_
27	which	_	PRON	_	PronType=Rel	_	_	_	_
28	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
29	part	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	normal	_	ADJ	_	Degree=Pos	_	_	_	_
33	NF	_	NOUN	_	Number=Sing	_	_	_	_
34	-	_	PUNCT	_	_	_	_	_	_
35	kappa	_	NOUN	_	Number=Sing	_	_	_	_
36	B	_	NOUN	_	Number=Sing	_	_	_	_
37	complex	_	NOUN	_	Number=Sing	_	_	_	_
38	,	_	PUNCT	_	_	_	_	_	_
39	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
40	not	_	PART	_	_	_	_	_	_
41	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
42	in	_	ADP	_	_	_	_	_	_
43	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
44	nucleus	_	ADJ	_	Number=Sing	_	_	_	_
45	following	_	VERB	_	VerbForm=Ger	_	_	_	_
46	activation	_	NOUN	_	Number=Sing	_	_	_	_
47	.	_	PUNCT	_	_	_	_	_	_

1	Western	_	ADJ	_	Degree=Pos	_	_	_	_
2	blotting	_	NOUN	_	Number=Sing	_	_	_	_
3	analysis	_	NOUN	_	Number=Sing	_	_	_	_
4	did	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	not	_	PART	_	_	_	_	_	_
6	detect	_	VERB	_	VerbForm=Inf	_	_	_	_
7	any	_	DET	_	_	_	_	_	_
8	RelA	_	NOUN	_	Number=Sing	_	_	_	_
9	in	_	ADP	_	_	_	_	_	_
10	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
11	extracts	_	NOUN	_	Number=Plur	_	_	_	_
12	either	_	ADV	_	_	_	_	_	_
13	before	_	ADV	_	_	_	_	_	_
14	or	_	CCONJ	_	_	_	_	_	_
15	after	_	ADP	_	_	_	_	_	_
16	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	T	_	NOUN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	altered	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
3	kappa	_	NOUN	_	Number=Sing	_	_	_	_
4	B	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	binding	_	NOUN	_	Number=Sing	_	_	_	_
7	activity	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	T	_	PROPN	_	Number=Sing	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	RCC	_	PROPN	_	Number=Sing	_	_	_	_
13	patients	_	NOUN	_	Number=Plur	_	_	_	_
14	may	_	AUX	_	VerbForm=Fin	_	_	_	_
15	impair	_	VERB	_	VerbForm=Inf	_	_	_	_
16	their	_	PRON	_	Number=Plur|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
17	capacity	_	NOUN	_	Number=Sing	_	_	_	_
18	to	_	PART	_	_	_	_	_	_
19	respond	_	VERB	_	VerbForm=Inf	_	_	_	_
20	normally	_	ADV	_	_	_	_	_	_
21	to	_	ADP	_	_	_	_	_	_
22	various	_	ADJ	_	Degree=Pos	_	_	_	_
23	stimuli	_	NOUN	_	Number=Plur	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013180	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Resistance	_	NOUN	_	Number=Sing	_	_	_	_
2	to	_	ADP	_	_	_	_	_	_
3	tumor	_	VERB	_	Number=Sing	_	_	_	_
4	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	vitro	_	NOUN	_	Number=Sing	_	_	_	_
10	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	with	_	ADP	_	_	_	_	_	_
12	high	_	ADJ	_	Degree=Pos	_	_	_	_
13	metastatic	_	ADJ	_	Degree=Pos	_	_	_	_
14	capacity	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	in	_	ADP	_	_	_	_	_	_
18	vivo	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	TNF	_	PROPN	_	Number=Sing	_	_	_	_
2	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	one	_	NUM	_	NumType=Card	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
7	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	cells	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	immune	_	NOUN	_	Number=Sing	_	_	_	_
14	system	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	demonstrate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
6	cell	_	NOUN	_	Number=Sing	_	_	_	_
7	lines	_	NOUN	_	Number=Plur	_	_	_	_
8	lacking	_	VERB	_	VerbForm=Ger	_	_	_	_
9	capability	_	NOUN	_	Number=Sing	_	_	_	_
10	to	_	PART	_	_	_	_	_	_
11	form	_	VERB	_	VerbForm=Inf	_	_	_	_
12	metastatic	_	ADJ	_	Degree=Pos	_	_	_	_
13	tumors	_	NOUN	_	Number=Plur	_	_	_	_
14	in	_	ADP	_	_	_	_	_	_
15	vivo	_	NOUN	_	Number=Sing	_	_	_	_
16	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
17	susceptible	_	ADJ	_	Degree=Pos	_	_	_	_
18	to	_	ADP	_	_	_	_	_	_
19	TNF	_	NOUN	_	Number=Sing	_	_	_	_
20	induced	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	apoptosis	_	NOUN	_	Number=Sing	_	_	_	_
22	in	_	ADP	_	_	_	_	_	_
23	vitro	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	However	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	lines	_	NOUN	_	Number=Plur	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	high	_	ADJ	_	Degree=Pos	_	_	_	_
7	metastatic	_	ADJ	_	Degree=Pos	_	_	_	_
8	potential	_	NOUN	_	Number=Sing	_	_	_	_
9	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
10	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
11	to	_	ADP	_	_	_	_	_	_
12	TNF	_	PROPN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	vitro	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	same	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	lines	_	NOUN	_	Number=Plur	_	_	_	_
7	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
8	resistant	_	ADJ	_	Degree=Pos	_	_	_	_
9	to	_	ADP	_	_	_	_	_	_
10	cytolytic	_	ADJ	_	Degree=Pos	_	_	_	_
11	action	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	other	_	ADJ	_	Degree=Pos	_	_	_	_
14	cytotoxic	_	ADJ	_	Degree=Pos	_	_	_	_
15	proteins	_	NOUN	_	Number=Plur	_	_	_	_
16	secreted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	by	_	ADP	_	_	_	_	_	_
18	LAK	_	PROPN	_	Number=Sing	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	data	_	NOUN	_	Number=Sing	_	_	_	_
3	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	TNF	_	PROPN	_	Number=Sing	_	_	_	_
6	resistance	_	NOUN	_	Number=Sing	_	_	_	_
7	in	_	ADP	_	_	_	_	_	_
8	vitro	_	NOUN	_	Number=Sing	_	_	_	_
9	correlates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
10	with	_	ADP	_	_	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
13	level	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	transcription	_	NOUN	_	Number=Sing	_	_	_	_
16	factor	_	NOUN	_	Number=Sing	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	PROPN	_	Number=Sing	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	finding	_	NOUN	_	Number=Sing	_	_	_	_
3	may	_	AUX	_	VerbForm=Fin	_	_	_	_
4	provide	_	VERB	_	VerbForm=Inf	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	tool	_	NOUN	_	Number=Sing	_	_	_	_
7	to	_	PART	_	_	_	_	_	_
8	improve	_	VERB	_	VerbForm=Inf	_	_	_	_
9	current	_	ADJ	_	Degree=Pos	_	_	_	_
10	protocols	_	NOUN	_	Number=Plur	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	immunotherapy	_	NOUN	_	Number=Sing	_	_	_	_
13	and	_	CCONJ	_	_	_	_	_	_
14	insights	_	NOUN	_	Number=Plur	_	_	_	_
15	to	_	SCONJ	_	_	_	_	_	_
16	how	_	ADV	_	PronType=Int	_	_	_	_
17	tumor	_	NOUN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
20	or	_	CCONJ	_	_	_	_	_	_
21	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
22	not	_	PART	_	_	_	_	_	_
23	killed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
24	by	_	ADP	_	_	_	_	_	_
25	LAK	_	PROPN	_	Number=Sing	_	_	_	_
26	cells	_	NOUN	_	Number=Plur	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013182	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Evidence	_	NOUN	_	Number=Sing	_	_	_	_
2	for	_	ADP	_	_	_	_	_	_
3	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
4	trans	_	NOUN	_	Number=Sing	_	_	_	_
5	-	_	PUNCT	_	_	_	_	_	_
6	acting	_	VERB	_	VerbForm=Ger	_	_	_	_
7	activator	_	NOUN	_	Number=Sing	_	_	_	_
8	function	_	NOUN	_	Number=Sing	_	_	_	_
9	regulating	_	VERB	_	VerbForm=Ger	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	human	_	ADJ	_	Degree=Pos	_	_	_	_
15	CD5	_	NOUN	_	Number=Sing	_	_	_	_
16	antigen	_	NOUN	_	Number=Sing	_	_	_	_
17	.	_	PUNCT	_	_	_	_	_	_

1	Interspecies	_	NOUN	_	_	_	_	_	_
2	somatic	_	ADJ	_	Degree=Pos	_	_	_	_
3	cell	_	NOUN	_	Number=Sing	_	_	_	_
4	hybrids	_	NOUN	_	Number=Plur	_	_	_	_
5	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
6	generated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
7	by	_	SCONJ	_	_	_	_	_	_
8	fusing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
10	mouse	_	NOUN	_	Number=Sing	_	_	_	_
11	T-lymphoma	_	PROPN	_	Number=Sing	_	_	_	_
12	cell	_	NOUN	_	Number=Sing	_	_	_	_
13	line	_	NOUN	_	Number=Sing	_	_	_	_
14	,	_	PUNCT	_	_	_	_	_	_
15	BW5147	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	with	_	ADP	_	_	_	_	_	_
18	normal	_	ADJ	_	Degree=Pos	_	_	_	_
19	human	_	ADJ	_	Degree=Pos	_	_	_	_
20	T	_	NOUN	_	Number=Sing	_	_	_	_
21	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
22	at	_	ADP	_	_	_	_	_	_
23	different	_	ADJ	_	Degree=Pos	_	_	_	_
24	stages	_	NOUN	_	Number=Plur	_	_	_	_
25	of	_	ADP	_	_	_	_	_	_
26	differentiation	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Thymocytes	_	NOUN	_	Number=Plur	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
5	T	_	NOUN	_	Number=Sing	_	_	_	_
6	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
11	T-cell	_	NOUN	_	Number=Sing	_	_	_	_
12	clone	_	NOUN	_	Number=Sing	_	_	_	_
13	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
14	used	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
15	as	_	ADP	_	_	_	_	_	_
16	human	_	ADJ	_	Degree=Pos	_	_	_	_
17	partners	_	NOUN	_	Number=Plur	_	_	_	_
18	,	_	PUNCT	_	_	_	_	_	_
19	respectively	_	ADV	_	_	_	_	_	_
20	,	_	PUNCT	_	_	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	three	_	NUM	_	NumType=Card	_	_	_	_
23	independent	_	ADJ	_	Degree=Pos	_	_	_	_
24	fusions	_	NOUN	_	Number=Plur	_	_	_	_
25	.	_	PUNCT	_	_	_	_	_	_

1	Irrespective	_	ADJ	_	_	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	human	_	ADJ	_	Degree=Pos	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	partner	_	NOUN	_	Number=Sing	_	_	_	_
7	used	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	for	_	ADP	_	_	_	_	_	_
9	fusion	_	NOUN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	certain	_	ADJ	_	Degree=Pos	_	_	_	_
13	number	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	hybrids	_	NOUN	_	Number=Plur	_	_	_	_
16	lost	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	CD5	_	PROPN	_	Number=Sing	_	_	_	_
18	surface	_	NOUN	_	Number=Sing	_	_	_	_
19	expression	_	NOUN	_	Number=Sing	_	_	_	_
20	over	_	ADP	_	_	_	_	_	_
21	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
22	period	_	NOUN	_	Number=Sing	_	_	_	_
23	of	_	ADP	_	_	_	_	_	_
24	time	_	NOUN	_	Number=Sing	_	_	_	_
25	in	_	ADP	_	_	_	_	_	_
26	culture	_	NOUN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Analysis	_	NOUN	_	Number=Sing	_	_	_	_
2	at	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	phenotype	_	NOUN	_	Number=Sing	_	_	_	_
5	and	_	CCONJ	_	_	_	_	_	_
6	genetic	_	ADJ	_	Degree=Pos	_	_	_	_
7	level	_	NOUN	_	Number=Sing	_	_	_	_
8	showed	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
9	that	_	DET	_	_	_	_	_	_
10	lack	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	CD5	_	PROPN	_	Number=Sing	_	_	_	_
13	expression	_	NOUN	_	Number=Sing	_	_	_	_
14	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
15	due	_	ADP	_	_	_	_	_	_
16	neither	_	CCONJ	_	_	_	_	_	_
17	to	_	ADP	_	_	_	_	_	_
18	segregation	_	NOUN	_	Number=Sing	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	human	_	ADJ	_	Degree=Pos	_	_	_	_
21	autosome	_	NOUN	_	Number=Sing	_	_	_	_
22	11	_	NUM	_	NumType=Card	_	_	_	_
23	,	_	PUNCT	_	_	_	_	_	_
24	on	_	ADP	_	_	_	_	_	_
25	which	_	PRON	_	PronType=Rel	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	CD5	_	PROPN	_	Number=Sing	_	_	_	_
28	gene	_	NOUN	_	Number=Sing	_	_	_	_
29	has	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
30	been	_	AUX	_	Tense=Past|VerbForm=Part	_	_	_	_
31	mapped	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	,	_	PUNCT	_	_	_	_	_	_
33	nor	_	CCONJ	_	_	_	_	_	_
34	to	_	ADP	_	_	_	_	_	_
35	deletion	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
38	CD5	_	PROPN	_	Number=Sing	_	_	_	_
39	structural	_	ADJ	_	Degree=Pos	_	_	_	_
40	gene	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Furthermore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	loss	_	NOUN	_	Number=Sing	_	_	_	_
4	of	_	ADP	_	_	_	_	_	_
5	CD5	_	NOUN	_	Number=Sing	_	_	_	_
6	surface	_	NOUN	_	Number=Sing	_	_	_	_
7	expression	_	NOUN	_	Number=Sing	_	_	_	_
8	correlated	_	VERB	_	Degree=Pos	_	_	_	_
9	with	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	absence	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	specific	_	ADJ	_	Degree=Pos	_	_	_	_
14	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
15	.	_	PUNCT	_	_	_	_	_	_

1	Since	_	SCONJ	_	_	_	_	_	_
2	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
3	hybrids	_	NOUN	_	Number=Plur	_	_	_	_
4	preferentially	_	ADV	_	_	_	_	_	_
5	segregate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
6	human	_	ADJ	_	Degree=Pos	_	_	_	_
7	chromosomes	_	NOUN	_	Number=Plur	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	these	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
10	results	_	NOUN	_	Number=Plur	_	_	_	_
11	indicate	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	existence	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
16	non-syntenic	_	ADJ	_	Degree=Pos	_	_	_	_
17	trans	_	NOUN	_	Number=Plur	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	active	_	ADJ	_	Degree=Pos	_	_	_	_
20	locus	_	NOUN	_	Number=Sing	_	_	_	_
21	,	_	PUNCT	_	_	_	_	_	_
22	or	_	CCONJ	_	_	_	_	_	_
23	loci	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	positively	_	ADV	_	_	_	_	_	_
26	controlling	_	VERB	_	VerbForm=Ger	_	_	_	_
27	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
28	expression	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
31	human	_	ADJ	_	Degree=Pos	_	_	_	_
32	CD5	_	NOUN	_	Number=Sing	_	_	_	_
33	gene	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013186	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Suppression	_	NOUN	_	Number=Sing	_	_	_	_
2	by	_	ADP	_	_	_	_	_	_
3	azelastine	_	ADJ	_	Degree=Pos	_	_	_	_
4	hydrochloride	_	NOUN	_	Number=Sing	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	NF	_	PROPN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	kappa	_	NOUN	_	Number=Sing	_	_	_	_
9	B	_	NOUN	_	Number=Sing	_	_	_	_
10	activation	_	NOUN	_	Number=Sing	_	_	_	_
11	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
12	in	_	ADP	_	_	_	_	_	_
13	generation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	nitric	_	ADJ	_	Degree=Pos	_	_	_	_
18	oxide	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	influence	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	anti-allergy	_	NOUN	_	Number=Sing	_	_	_	_
6	agent	_	NOUN	_	Number=Sing	_	_	_	_
7	azelastine	_	PROPN	_	Number=Sing	_	_	_	_
8	hydrochloride	_	NOUN	_	Number=Sing	_	_	_	_
9	(	_	PUNCT	_	_	_	_	_	_
10	Azeptin	_	PROPN	_	Number=Sing	_	_	_	_
11	)	_	PUNCT	_	_	_	_	_	_
12	on	_	ADP	_	_	_	_	_	_
13	NF	_	PROPN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	kappa	_	NOUN	_	Number=Sing	_	_	_	_
16	B	_	NOUN	_	Number=Sing	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	associated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
19	with	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	generation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
24	and	_	CCONJ	_	_	_	_	_	_
25	nitric	_	ADJ	_	Number=Sing	_	_	_	_
26	oxide	_	NOUN	_	Number=Sing	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	NO	_	INTJ	_	_	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
31	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
32	in	_	ADP	_	_	_	_	_	_
33	various	_	ADJ	_	Degree=Pos	_	_	_	_
34	kinds	_	NOUN	_	Number=Plur	_	_	_	_
35	of	_	ADP	_	_	_	_	_	_
36	human	_	ADJ	_	Degree=Pos	_	_	_	_
37	and	_	CCONJ	_	_	_	_	_	_
38	mouse	_	NOUN	_	Number=Sing	_	_	_	_
39	cells	_	NOUN	_	Number=Plur	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	Azeptin	_	PROPN	_	Number=Sing	_	_	_	_
2	dose	_	NOUN	_	Number=Sing	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	dependently	_	ADV	_	_	_	_	_	_
5	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	both	_	CCONJ	_	_	_	_	_	_
7	DNA	_	PROPN	_	Number=Sing	_	_	_	_
8	and	_	CCONJ	_	_	_	_	_	_
9	protein	_	VERB	_	Number=Sing	_	_	_	_
10	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
11	in	_	ADP	_	_	_	_	_	_
12	human	_	ADJ	_	Degree=Pos	_	_	_	_
13	gingival	_	NOUN	_	Number=Sing	_	_	_	_
14	fibroblasts	_	NOUN	_	Number=Plur	_	_	_	_
15	(	_	PUNCT	_	_	_	_	_	_
16	HF	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	and	_	CCONJ	_	_	_	_	_	_
19	also	_	ADV	_	_	_	_	_	_
20	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
21	blastogenesis	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	human	_	ADJ	_	Degree=Pos	_	_	_	_
24	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
25	blood	_	NOUN	_	Number=Sing	_	_	_	_
26	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	PBL	_	NOUN	_	Number=Sing	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Generation	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	tumor	_	NOUN	_	Number=Sing	_	_	_	_
4	necrosis	_	NOUN	_	Number=Sing	_	_	_	_
5	factor	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	alpha	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	-	_	PUNCT	_	_	_	_	_	_
12	beta	_	NOUN	_	Number=Sing	_	_	_	_
13	,	_	PUNCT	_	_	_	_	_	_
14	granulocyte	_	NOUN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	macrophage	_	NOUN	_	Number=Sing	_	_	_	_
17	colony	_	NOUN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	stimulating	_	ADJ	_	Degree=Pos	_	_	_	_
20	factor	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	interleukin	_	NOUN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	6	_	NUM	_	NumType=Card	_	_	_	_
25	from	_	ADP	_	_	_	_	_	_
26	10	_	NUM	_	NumType=Card	_	_	_	_
27	(	_	PUNCT	_	_	_	_	_	_
28	-5	_	NUM	_	NumType=Card	_	_	_	_
29	)	_	PUNCT	_	_	_	_	_	_
30	M	_	NUM	_	NumType=Card	_	_	_	_
31	Azeptin	_	NOUN	_	Number=Sing	_	_	_	_
32	-	_	PUNCT	_	_	_	_	_	_
33	treated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	PBL	_	NOUN	_	Number=Sing	_	_	_	_
35	and	_	CCONJ	_	_	_	_	_	_
36	human	_	ADJ	_	Degree=Pos	_	_	_	_
37	monocytes	_	NOUN	_	Number=Plur	_	_	_	_
38	(	_	PUNCT	_	_	_	_	_	_
39	HM	_	NOUN	_	Number=Sing	_	_	_	_
40	)	_	PUNCT	_	_	_	_	_	_
41	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
42	decreased	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	approximately	_	ADV	_	_	_	_	_	_
45	1	_	NUM	_	NumType=Card	_	_	_	_
46	/	_	PUNCT	_	_	_	_	_	_
47	3	_	NUM	_	NumType=Card	_	_	_	_
48	to	_	ADP	_	_	_	_	_	_
49	2	_	NUM	_	NumType=Card	_	_	_	_
50	/	_	PUNCT	_	_	_	_	_	_
51	3	_	NUM	_	NumType=Card	_	_	_	_
52	of	_	ADP	_	_	_	_	_	_
53	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
54	control	_	NOUN	_	Number=Sing	_	_	_	_
55	levels	_	NOUN	_	Number=Plur	_	_	_	_
56	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	parallel	_	NOUN	_	Number=Sing	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
5	decreased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
6	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
7	generation	_	NOUN	_	Number=Sing	_	_	_	_
8	,	_	PUNCT	_	_	_	_	_	_
9	each	_	DET	_	_	_	_	_	_
10	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
11	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	less	_	ADV	_	Degree=Cmp	_	_	_	_
14	expressed	_	ADJ	_	Degree=Pos	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
17	presence	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	10	_	NUM	_	NumType=Card	_	_	_	_
20	(-5	_	NUM	_	NumType=Card	_	_	_	_
21	)	_	PUNCT	_	_	_	_	_	_
22	M	_	PROPN	_	Number=Sing	_	_	_	_
23	Azeptin	_	PROPN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	addition	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	both	_	CCONJ	_	_	_	_	_	_
5	inducible	_	ADJ	_	Degree=Pos	_	_	_	_
6	nitric	_	ADJ	_	Degree=Pos	_	_	_	_
7	oxide	_	NOUN	_	Number=Sing	_	_	_	_
8	synthase	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	mRNA	_	NOUN	_	Number=Sing	_	_	_	_
11	level	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	NO	_	DET	_	_	_	_	_	_
14	generation	_	NOUN	_	Number=Sing	_	_	_	_
15	in	_	ADP	_	_	_	_	_	_
16	mouse	_	NOUN	_	Number=Sing	_	_	_	_
17	peritoneal	_	ADJ	_	Degree=Pos	_	_	_	_
18	macrophages	_	NOUN	_	Number=Plur	_	_	_	_
19	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	suppressed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	by	_	ADP	_	_	_	_	_	_
22	10	_	NUM	_	NumType=Card	_	_	_	_
23	(-5	_	NUM	_	NumType=Card	_	_	_	_
24	)	_	PUNCT	_	_	_	_	_	_
25	M	_	PROPN	_	Number=Sing	_	_	_	_
26	Azeptin	_	PROPN	_	Number=Sing	_	_	_	_
27	.	_	PUNCT	_	_	_	_	_	_

1	Being	_	AUX	_	VerbForm=Ger	_	_	_	_
2	compatible	_	ADJ	_	Degree=Pos	_	_	_	_
3	with	_	ADP	_	_	_	_	_	_
4	those	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
5	results	_	NOUN	_	Number=Plur	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	Azeptin	_	PROPN	_	Number=Sing	_	_	_	_
8	(	_	PUNCT	_	_	_	_	_	_
9	10	_	NUM	_	NumType=Card	_	_	_	_
10	(	_	PUNCT	_	_	_	_	_	_
11	-	_	SYM	_	_	_	_	_	_
12	5	_	NUM	_	NumType=Card	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	M	_	NUM	_	NumType=Card	_	_	_	_
15	)	_	PUNCT	_	_	_	_	_	_
16	suppressed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
17	activation	_	NOUN	_	Number=Sing	_	_	_	_
18	of	_	ADP	_	_	_	_	_	_
19	NF	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	kappa	_	PROPN	_	Number=Sing	_	_	_	_
22	B	_	NOUN	_	Number=Sing	_	_	_	_
23	in	_	ADP	_	_	_	_	_	_
24	PBL	_	PROPN	_	Number=Sing	_	_	_	_
25	,	_	PUNCT	_	_	_	_	_	_
26	HM	_	PROPN	_	Number=Sing	_	_	_	_
27	and	_	CCONJ	_	_	_	_	_	_
28	HF	_	PROPN	_	Number=Sing	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	These	_	DET	_	Number=Plur|PronType=Dem	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	appear	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	to	_	PART	_	_	_	_	_	_
5	indicate	_	VERB	_	VerbForm=Inf	_	_	_	_
6	that	_	DET	_	_	_	_	_	_
7	suppression	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
10	and	_	CCONJ	_	_	_	_	_	_
11	NO	_	DET	_	_	_	_	_	_
12	generation	_	NOUN	_	Number=Sing	_	_	_	_
13	by	_	ADP	_	_	_	_	_	_
14	Azeptin	_	PROPN	_	Number=Sing	_	_	_	_
15	results	_	NOUN	_	Number=Plur	_	_	_	_
16	at	_	ADV	_	_	_	_	_	_
17	least	_	ADV	_	Degree=Sup	_	_	_	_
18	partially	_	ADV	_	_	_	_	_	_
19	from	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	NF	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	kappa	_	NOUN	_	Number=Sing	_	_	_	_
26	B	_	NOUN	_	Number=Sing	_	_	_	_
27	activation	_	NOUN	_	Number=Sing	_	_	_	_
28	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013190	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Affinity	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	driven	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	peptide	_	NOUN	_	Number=Sing	_	_	_	_
5	selection	_	NOUN	_	Number=Sing	_	_	_	_
6	of	_	ADP	_	_	_	_	_	_
7	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
8	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
9	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
10	more	_	ADV	_	_	_	_	_	_
11	selective	_	ADJ	_	Degree=Pos	_	_	_	_
12	than	_	ADP	_	_	_	_	_	_
13	cyclosporin	_	NOUN	_	Number=Sing	_	_	_	_
14	A	_	NOUN	_	Number=Sing	_	_	_	_
15	[	_	PUNCT	_	_	_	_	_	_
16	see	_	VERB	_	Mood=Imp|VerbForm=Fin	_	_	_	_
17	comments	_	NOUN	_	Number=Plur	_	_	_	_
18	]	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	flow	_	NOUN	_	Number=Sing	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	information	_	NOUN	_	Number=Sing	_	_	_	_
5	from	_	ADP	_	_	_	_	_	_
6	calcium	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	mobilizing	_	VERB	_	VerbForm=Ger	_	_	_	_
9	receptors	_	NOUN	_	Number=Plur	_	_	_	_
10	to	_	ADP	_	_	_	_	_	_
11	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
12	factor	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	activated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
15	T	_	NOUN	_	Number=Sing	_	_	_	_
16	cells	_	NOUN	_	Number=Plur	_	_	_	_
17	(	_	PUNCT	_	_	_	_	_	_
18	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
19	)	_	PUNCT	_	_	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
22	genes	_	NOUN	_	Number=Plur	_	_	_	_
23	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
24	critically	_	ADV	_	_	_	_	_	_
25	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
26	on	_	ADP	_	_	_	_	_	_
27	interaction	_	NOUN	_	Number=Sing	_	_	_	_
28	between	_	ADP	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
31	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
32	and	_	CCONJ	_	_	_	_	_	_
33	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
34	transcription	_	NOUN	_	Number=Sing	_	_	_	_
35	factor	_	NOUN	_	Number=Sing	_	_	_	_
36	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
37	.	_	PUNCT	_	_	_	_	_	_

1	A	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
2	high	_	ADJ	_	Degree=Pos	_	_	_	_
3	-	_	PUNCT	_	_	_	_	_	_
4	affinity	_	NOUN	_	Number=Sing	_	_	_	_
5	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
6	-	_	PUNCT	_	_	_	_	_	_
7	binding	_	VERB	_	Number=Sing	_	_	_	_
8	peptide	_	NOUN	_	Number=Sing	_	_	_	_
9	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
10	selected	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	from	_	ADP	_	_	_	_	_	_
12	combinatorial	_	ADJ	_	Degree=Pos	_	_	_	_
13	peptide	_	NOUN	_	Number=Sing	_	_	_	_
14	libraries	_	NOUN	_	Number=Plur	_	_	_	_
15	based	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
16	on	_	ADP	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
19	docking	_	NOUN	_	Number=Sing	_	_	_	_
20	motif	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
23	.	_	PUNCT	_	_	_	_	_	_

1	This	_	DET	_	Number=Sing|PronType=Dem	_	_	_	_
2	peptide	_	NOUN	_	Number=Sing	_	_	_	_
3	potently	_	ADV	_	_	_	_	_	_
4	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
5	NFAT	_	PROPN	_	Number=Sing	_	_	_	_
6	activation	_	NOUN	_	Number=Sing	_	_	_	_
7	and	_	CCONJ	_	_	_	_	_	_
8	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
9	-	_	PUNCT	_	_	_	_	_	_
10	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
11	expression	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	endogenous	_	ADJ	_	Degree=Pos	_	_	_	_
14	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
15	genes	_	NOUN	_	Number=Plur	_	_	_	_
16	in	_	ADP	_	_	_	_	_	_
17	T	_	PROPN	_	Number=Sing	_	_	_	_
18	cells	_	NOUN	_	Number=Plur	_	_	_	_
19	,	_	PUNCT	_	_	_	_	_	_
20	without	_	SCONJ	_	_	_	_	_	_
21	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	expression	_	NOUN	_	Number=Sing	_	_	_	_
24	of	_	ADP	_	_	_	_	_	_
25	other	_	ADJ	_	Degree=Pos	_	_	_	_
26	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
27	that	_	PRON	_	PronType=Rel	_	_	_	_
28	require	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
29	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
30	but	_	CCONJ	_	_	_	_	_	_
31	not	_	ADV	_	_	_	_	_	_
32	NFAT	_	NOUN	_	Degree=Pos	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	Substitution	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	optimized	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
5	peptide	_	NOUN	_	Number=Sing	_	_	_	_
6	sequence	_	NOUN	_	Number=Sing	_	_	_	_
7	into	_	ADP	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	natural	_	ADJ	_	Degree=Pos	_	_	_	_
10	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
11	docking	_	NOUN	_	Number=Sing	_	_	_	_
12	site	_	NOUN	_	Number=Sing	_	_	_	_
13	increased	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
16	responsiveness	_	NOUN	_	Number=Sing	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	NFAT	_	NOUN	_	Number=Sing	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Compounds	_	NOUN	_	Number=Plur	_	_	_	_
2	that	_	PRON	_	PronType=Rel	_	_	_	_
3	interfere	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	selectively	_	ADV	_	_	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
7	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	NFAT	_	ADJ	_	Number=Sing	_	_	_	_
10	interaction	_	NOUN	_	Number=Sing	_	_	_	_
11	without	_	SCONJ	_	_	_	_	_	_
12	affecting	_	VERB	_	VerbForm=Ger	_	_	_	_
13	calcineurin	_	NOUN	_	Number=Sing	_	_	_	_
14	phosphatase	_	NOUN	_	Number=Sing	_	_	_	_
15	activity	_	NOUN	_	Number=Sing	_	_	_	_
16	may	_	AUX	_	VerbForm=Fin	_	_	_	_
17	be	_	AUX	_	VerbForm=Inf	_	_	_	_
18	useful	_	ADJ	_	Degree=Pos	_	_	_	_
19	as	_	ADP	_	_	_	_	_	_
20	therapeutic	_	ADJ	_	Degree=Pos	_	_	_	_
21	agents	_	NOUN	_	Number=Plur	_	_	_	_
22	that	_	PRON	_	PronType=Rel	_	_	_	_
23	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
24	less	_	ADV	_	Degree=Cmp	_	_	_	_
25	toxic	_	ADJ	_	Degree=Pos	_	_	_	_
26	than	_	ADP	_	_	_	_	_	_
27	current	_	ADJ	_	Degree=Pos	_	_	_	_
28	drugs	_	NOUN	_	Number=Plur	_	_	_	_
29	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013195	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Effects	_	NOUN	_	Number=Plur	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	prostaglandin	_	PROPN	_	Number=Sing	_	_	_	_
4	E2	_	PROPN	_	Number=Sing	_	_	_	_
5	on	_	ADP	_	_	_	_	_	_
6	Th0	_	NUM	_	NumType=Card	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	type	_	NOUN	_	Number=Sing	_	_	_	_
9	human	_	ADJ	_	Degree=Pos	_	_	_	_
10	T	_	NOUN	_	Number=Sing	_	_	_	_
11	cell	_	NOUN	_	Number=Sing	_	_	_	_
12	clones	_	NOUN	_	Number=Plur	_	_	_	_
13	:	_	PUNCT	_	_	_	_	_	_
14	modulation	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	functions	_	NOUN	_	Number=Plur	_	_	_	_
17	of	_	ADP	_	_	_	_	_	_
18	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
19	proteins	_	NOUN	_	Number=Plur	_	_	_	_
20	involved	_	ADJ	_	Tense=Past|VerbForm=Part	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
23	production	_	NOUN	_	Number=Sing	_	_	_	_
24	.	_	PUNCT	_	_	_	_	_	_

1	The	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
2	effects	_	NOUN	_	Number=Plur	_	_	_	_
3	of	_	ADP	_	_	_	_	_	_
4	prostaglandin	_	PROPN	_	Number=Sing	_	_	_	_
5	E2	_	PROPN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	PGE2	_	NOUN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	cytokine	_	NOUN	_	Number=Sing	_	_	_	_
11	production	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
14	of	_	ADP	_	_	_	_	_	_
15	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
16	CD4	_	NOUN	_	Number=Sing	_	_	_	_
17	+	_	SYM	_	_	_	_	_	_

1	human	_	ADJ	_	Degree=Pos	_	_	_	_
2	helper	_	NOUN	_	Number=Sing	_	_	_	_
3	T	_	NOUN	_	Number=Sing	_	_	_	_
4	cell	_	NOUN	_	Number=Sing	_	_	_	_
5	clone	_	NOUN	_	Number=Sing	_	_	_	_
6	SP	_	NOUN	_	Number=Sing	_	_	_	_
7	-	_	PUNCT	_	_	_	_	_	_
8	B21	_	NOUN	_	Number=Sing	_	_	_	_
9	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
10	investigated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
11	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
4	with	_	ADP	_	_	_	_	_	_
5	anti-CD3	_	PROPN	_	Degree=Pos	_	_	_	_
6	mAb	_	NOUN	_	Number=Sing	_	_	_	_
7	,	_	PUNCT	_	_	_	_	_	_
8	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
9	inhibited	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
10	cell	_	NOUN	_	Number=Sing	_	_	_	_
11	proliferation	_	NOUN	_	Number=Sing	_	_	_	_
12	and	_	CCONJ	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	production	_	NOUN	_	Number=Sing	_	_	_	_
15	of	_	ADP	_	_	_	_	_	_
16	all	_	DET	_	_	_	_	_	_
17	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
18	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
19	examined	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
20	.	_	PUNCT	_	_	_	_	_	_

1	Addition	_	NOUN	_	Number=Sing	_	_	_	_
2	of	_	ADP	_	_	_	_	_	_
3	rIL	_	NOUN	_	Number=Sing	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	2	_	NUM	_	NumType=Card	_	_	_	_
6	fully	_	ADV	_	_	_	_	_	_
7	restored	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	proliferative	_	ADJ	_	Degree=Pos	_	_	_	_
10	response	_	NOUN	_	Number=Sing	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	partially	_	ADV	_	_	_	_	_	_
13	restored	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	production	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	IL	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	4	_	NUM	_	NumType=Card	_	_	_	_
20	and	_	CCONJ	_	_	_	_	_	_
21	IL	_	PROPN	_	Number=Sing	_	_	_	_
22	-	_	SYM	_	_	_	_	_	_
23	5	_	NUM	_	NumType=Card	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	but	_	CCONJ	_	_	_	_	_	_
26	not	_	ADV	_	_	_	_	_	_
27	that	_	PRON	_	Number=Sing|PronType=Dem	_	_	_	_
28	of	_	ADP	_	_	_	_	_	_
29	other	_	ADJ	_	Degree=Pos	_	_	_	_
30	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	contrast	_	NOUN	_	Number=Sing	_	_	_	_
3	,	_	PUNCT	_	_	_	_	_	_
4	in	_	ADP	_	_	_	_	_	_
5	cells	_	NOUN	_	Number=Plur	_	_	_	_
6	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
7	with	_	ADP	_	_	_	_	_	_
8	phorbol	_	NOUN	_	Number=Sing	_	_	_	_
9	myristate	_	NOUN	_	Number=Sing	_	_	_	_
10	acetate	_	NOUN	_	Number=Sing	_	_	_	_
11	(	_	PUNCT	_	_	_	_	_	_
12	PMA	_	PROPN	_	Number=Sing	_	_	_	_
13	)	_	PUNCT	_	_	_	_	_	_
14	/	_	PUNCT	_	_	_	_	_	_
15	A23187	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
18	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
19	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
20	production	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	IL	_	PROPN	_	Number=Sing	_	_	_	_
23	-	_	PUNCT	_	_	_	_	_	_
24	4	_	NUM	_	NumType=Card	_	_	_	_
25	and	_	CCONJ	_	_	_	_	_	_
26	IL	_	PROPN	_	Number=Sing	_	_	_	_
27	-	_	SYM	_	_	_	_	_	_
28	5	_	NUM	_	NumType=Card	_	_	_	_
29	,	_	PUNCT	_	_	_	_	_	_
30	and	_	CCONJ	_	_	_	_	_	_
31	only	_	ADV	_	_	_	_	_	_
32	partially	_	ADV	_	_	_	_	_	_
33	inhibited	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
34	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
35	production	_	NOUN	_	Number=Sing	_	_	_	_
36	of	_	ADP	_	_	_	_	_	_
37	other	_	ADJ	_	Degree=Pos	_	_	_	_
38	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
39	.	_	PUNCT	_	_	_	_	_	_

1	Therefore	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	effects	_	NOUN	_	Number=Plur	_	_	_	_
5	of	_	ADP	_	_	_	_	_	_
6	PGE2	_	NOUN	_	Number=Sing	_	_	_	_
7	vary	_	VERB	_	Number=Sing	_	_	_	_
8	depending	_	VERB	_	VerbForm=Ger	_	_	_	_
9	on	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	mode	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	T	_	NOUN	_	Number=Sing	_	_	_	_
14	cell	_	NOUN	_	Number=Sing	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	,	_	PUNCT	_	_	_	_	_	_
17	and	_	CCONJ	_	_	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	IL	_	PROPN	_	Number=Sing	_	_	_	_
20	-	_	PUNCT	_	_	_	_	_	_
21	4	_	NUM	_	NumType=Card	_	_	_	_
22	and	_	CCONJ	_	_	_	_	_	_
23	IL	_	PROPN	_	Number=Sing	_	_	_	_
24	-	_	PUNCT	_	_	_	_	_	_
25	5	_	NUM	_	NumType=Card	_	_	_	_
26	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
27	regulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
28	differently	_	ADV	_	_	_	_	_	_
29	from	_	ADP	_	_	_	_	_	_
30	other	_	ADJ	_	Degree=Pos	_	_	_	_
31	cytokines	_	NOUN	_	Number=Plur	_	_	_	_
32	.	_	PUNCT	_	_	_	_	_	_

1	In	_	ADP	_	_	_	_	_	_
2	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
3	mobility	_	NOUN	_	Number=Sing	_	_	_	_
4	shift	_	NOUN	_	Number=Sing	_	_	_	_
5	assay	_	NOUN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	only	_	ADV	_	_	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappa	_	NOUN	_	Number=Sing	_	_	_	_
12	B	_	NOUN	_	Number=Sing	_	_	_	_
13	(	_	PUNCT	_	_	_	_	_	_
14	p50	_	NOUN	_	Number=Sing	_	_	_	_
15	/	_	PUNCT	_	_	_	_	_	_
16	p50	_	NOUN	_	Number=Sing	_	_	_	_
17	)	_	PUNCT	_	_	_	_	_	_
18	homodimer	_	NOUN	_	Number=Sing	_	_	_	_
19	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
20	observed	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
21	in	_	ADP	_	_	_	_	_	_
22	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
23	complex	_	NOUN	_	Number=Sing	_	_	_	_
24	formed	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
27	kappa	_	NOUN	_	Number=Sing	_	_	_	_
28	B	_	NOUN	_	Number=Sing	_	_	_	_
29	sequence	_	NOUN	_	Number=Sing	_	_	_	_
30	in	_	ADP	_	_	_	_	_	_
31	unstimulated	_	ADJ	_	Degree=Pos	_	_	_	_
32	SP	_	NOUN	_	Number=Sing	_	_	_	_
33	-	_	PUNCT	_	_	_	_	_	_
34	B21	_	NUM	_	Number=Sing	_	_	_	_
35	cells	_	NOUN	_	Number=Plur	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	When	_	ADV	_	PronType=Int	_	_	_	_
2	cells	_	NOUN	_	Number=Plur	_	_	_	_
3	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
4	stimulated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
5	with	_	ADP	_	_	_	_	_	_
6	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
7	mAb	_	NOUN	_	Number=Sing	_	_	_	_
8	or	_	CCONJ	_	_	_	_	_	_
9	PMA	_	PROPN	_	Number=Sing	_	_	_	_
10	/	_	PUNCT	_	_	_	_	_	_
11	A23187	_	NOUN	_	Number=Sing	_	_	_	_
12	,	_	PUNCT	_	_	_	_	_	_
13	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
14	complex	_	ADJ	_	Degree=Pos	_	_	_	_
15	formation	_	NOUN	_	Number=Sing	_	_	_	_
16	of	_	ADP	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappa	_	NOUN	_	Number=Sing	_	_	_	_
20	B	_	NOUN	_	Number=Sing	_	_	_	_
21	(	_	PUNCT	_	_	_	_	_	_
22	p50	_	NOUN	_	Number=Sing	_	_	_	_
23	/	_	PUNCT	_	_	_	_	_	_
24	p65	_	NOUN	_	Number=Sing	_	_	_	_
25	)	_	PUNCT	_	_	_	_	_	_
26	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
27	with	_	ADP	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	kappa	_	NOUN	_	Number=Sing	_	_	_	_
30	B	_	NOUN	_	Number=Sing	_	_	_	_
31	sequence	_	NOUN	_	Number=Sing	_	_	_	_
32	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
33	induced	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	Interestingly	_	ADV	_	_	_	_	_	_
2	,	_	PUNCT	_	_	_	_	_	_
3	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
4	or	_	CCONJ	_	_	_	_	_	_
5	di-butyryl	_	NOUN	_	Number=Sing	_	_	_	_
6	(	_	PUNCT	_	_	_	_	_	_
7	Bt2	_	PROPN	_	Number=Sing	_	_	_	_
8	)	_	PUNCT	_	_	_	_	_	_
9	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
10	abolished	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
11	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
12	binding	_	NOUN	_	Number=Sing	_	_	_	_
13	of	_	ADP	_	_	_	_	_	_
14	NF	_	PROPN	_	Number=Sing	_	_	_	_
15	-	_	PUNCT	_	_	_	_	_	_
16	kappa	_	NOUN	_	Number=Sing	_	_	_	_
17	B	_	NOUN	_	Number=Sing	_	_	_	_
18	(	_	PUNCT	_	_	_	_	_	_
19	p50	_	NOUN	_	Number=Sing	_	_	_	_
20	/	_	PUNCT	_	_	_	_	_	_
21	p65	_	NOUN	_	Number=Sing	_	_	_	_
22	)	_	PUNCT	_	_	_	_	_	_
23	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
24	to	_	ADP	_	_	_	_	_	_
25	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
26	kappa	_	NOUN	_	Number=Sing	_	_	_	_
27	B	_	NOUN	_	Number=Sing	_	_	_	_
28	sequence	_	NOUN	_	Number=Sing	_	_	_	_
29	in	_	ADP	_	_	_	_	_	_
30	cells	_	NOUN	_	Number=Plur	_	_	_	_
31	stimulated	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
32	with	_	ADP	_	_	_	_	_	_
33	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
34	mAb	_	NOUN	_	Number=Sing	_	_	_	_
35	but	_	CCONJ	_	_	_	_	_	_
36	not	_	PART	_	_	_	_	_	_
37	with	_	ADP	_	_	_	_	_	_
38	PMA	_	PROPN	_	Number=Sing	_	_	_	_
39	/	_	PUNCT	_	_	_	_	_	_
40	A23187	_	NOUN	_	Number=Sing	_	_	_	_
41	.	_	PUNCT	_	_	_	_	_	_

1	Our	_	PRON	_	Number=Plur|Person=1|Poss=Yes|PronType=Prs	_	_	_	_
2	results	_	NOUN	_	Number=Plur	_	_	_	_
3	suggest	_	VERB	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
6	target	_	NOUN	_	Number=Sing	_	_	_	_
7	of	_	ADP	_	_	_	_	_	_
8	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
9	action	_	NOUN	_	Number=Sing	_	_	_	_
10	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
11	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
12	component	_	NOUN	_	Number=Sing	_	_	_	_
13	in	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	signal	_	ADJ	_	Number=Sing	_	_	_	_
16	transduction	_	NOUN	_	Number=Sing	_	_	_	_
17	pathway	_	NOUN	_	Number=Sing	_	_	_	_
18	leading	_	VERB	_	VerbForm=Ger	_	_	_	_
19	to	_	ADP	_	_	_	_	_	_
20	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
21	activation	_	NOUN	_	Number=Sing	_	_	_	_
22	of	_	ADP	_	_	_	_	_	_
23	protein	_	NOUN	_	Number=Sing	_	_	_	_
24	kinase	_	NOUN	_	Number=Sing	_	_	_	_
25	C.	_	PROPN	_	Number=Sing	_	_	_	_
26	However	_	ADV	_	_	_	_	_	_
27	,	_	PUNCT	_	_	_	_	_	_
28	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
29	inhibition	_	NOUN	_	Number=Sing	_	_	_	_
30	of	_	ADP	_	_	_	_	_	_
31	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
32	T	_	NOUN	_	Number=Sing	_	_	_	_
33	cell	_	NOUN	_	Number=Sing	_	_	_	_
34	activation	_	NOUN	_	Number=Sing	_	_	_	_
35	signals	_	NOUN	_	Number=Plur	_	_	_	_
36	by	_	ADP	_	_	_	_	_	_
37	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
38	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
39	selective	_	ADJ	_	Degree=Pos	_	_	_	_
40	.	_	PUNCT	_	_	_	_	_	_

1	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
2	enhanced	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
3	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
4	complex	_	ADJ	_	Degree=Pos	_	_	_	_
5	formation	_	NOUN	_	Number=Sing	_	_	_	_
6	with	_	ADP	_	_	_	_	_	_
7	NF	_	PROPN	_	Number=Sing	_	_	_	_
8	-	_	PUNCT	_	_	_	_	_	_
9	AT	_	PROPN	_	Number=Sing	_	_	_	_
10	,	_	PUNCT	_	_	_	_	_	_
11	AP	_	PROPN	_	Number=Sing	_	_	_	_
12	-	_	PUNCT	_	_	_	_	_	_
13	1	_	NUM	_	NumType=Card	_	_	_	_
14	and	_	CCONJ	_	_	_	_	_	_
15	CLE0	_	PROPN	_	Number=Sing	_	_	_	_
16	sequences	_	NOUN	_	Number=Plur	_	_	_	_
17	when	_	ADV	_	PronType=Int	_	_	_	_
18	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
19	cells	_	NOUN	_	Number=Plur	_	_	_	_
20	were	_	AUX	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
21	activated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
22	by	_	ADP	_	_	_	_	_	_
23	either	_	CCONJ	_	_	_	_	_	_
24	anti-CD3	_	PROPN	_	Number=Sing	_	_	_	_
25	mAb	_	NOUN	_	Number=Sing	_	_	_	_
26	or	_	CCONJ	_	_	_	_	_	_
27	PMA	_	PROPN	_	Number=Sing	_	_	_	_
28	/	_	PUNCT	_	_	_	_	_	_
29	A23187	_	NOUN	_	Number=Sing	_	_	_	_
30	stimulation	_	NOUN	_	Number=Sing	_	_	_	_
31	.	_	PUNCT	_	_	_	_	_	_

1	It	_	PRON	_	Case=Nom|Gender=Neut|Number=Sing|Person=3|PronType=Prs	_	_	_	_
2	seems	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
3	therefore	_	ADV	_	_	_	_	_	_
4	that	_	SCONJ	_	_	_	_	_	_
5	PGE2	_	PROPN	_	Number=Sing	_	_	_	_
6	,	_	PUNCT	_	_	_	_	_	_
7	by	_	SCONJ	_	_	_	_	_	_
8	elevating	_	VERB	_	VerbForm=Ger	_	_	_	_
9	cAMP	_	NOUN	_	Number=Sing	_	_	_	_
10	levels	_	NOUN	_	Number=Plur	_	_	_	_
11	,	_	PUNCT	_	_	_	_	_	_
12	interferes	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
13	with	_	ADP	_	_	_	_	_	_
14	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
15	activation	_	NOUN	_	Number=Sing	_	_	_	_
16	pathway	_	NOUN	_	Number=Sing	_	_	_	_
17	for	_	ADP	_	_	_	_	_	_
18	NF	_	PROPN	_	Number=Sing	_	_	_	_
19	-	_	PUNCT	_	_	_	_	_	_
20	kappa	_	PROPN	_	Number=Sing	_	_	_	_
21	B	_	NOUN	_	Number=Sing	_	_	_	_
22	but	_	CCONJ	_	_	_	_	_	_
23	not	_	ADV	_	_	_	_	_	_
24	for	_	ADP	_	_	_	_	_	_
25	NF	_	PROPN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	AT	_	NOUN	_	Number=Sing	_	_	_	_
28	,	_	PUNCT	_	_	_	_	_	_
29	AP	_	NOUN	_	Number=Sing	_	_	_	_
30	-	_	PUNCT	_	_	_	_	_	_
31	1	_	NUM	_	NumType=Card	_	_	_	_
32	or	_	CCONJ	_	_	_	_	_	_
33	CLE0	_	PROPN	_	Number=Sing	_	_	_	_
34	binding	_	VERB	_	Number=Sing	_	_	_	_
35	protein	_	NOUN	_	Number=Sing	_	_	_	_
36	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013198	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	contact	_	NOUN	_	Number=Sing	_	_	_	_
7	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
8	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
9	long	_	ADJ	_	Degree=Pos	_	_	_	_
10	terminal	_	NOUN	_	Number=Sing	_	_	_	_
11	repeat	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
15	virus	_	NOUN	_	Number=Sing	_	_	_	_
16	1	_	NUM	_	NumType=Card	_	_	_	_
17	through	_	ADP	_	_	_	_	_	_
18	its	_	PRON	_	Gender=Neut|Number=Sing|Person=3|Poss=Yes|PronType=Prs	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	motif	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	contact	_	NOUN	_	Number=Sing	_	_	_	_
7	between	_	ADP	_	_	_	_	_	_
8	peripheral	_	ADJ	_	Degree=Pos	_	_	_	_
9	blood	_	NOUN	_	Number=Sing	_	_	_	_
10	lymphocytes	_	NOUN	_	Number=Plur	_	_	_	_
11	and	_	CCONJ	_	_	_	_	_	_
12	transfected	_	VERB	_	Degree=Pos	_	_	_	_
13	human	_	ADJ	_	Degree=Pos	_	_	_	_
14	colonic	_	ADJ	_	Number=Sing	_	_	_	_
15	carcinoma	_	NOUN	_	Number=Sing	_	_	_	_
16	cell	_	NOUN	_	Number=Sing	_	_	_	_
17	line	_	NOUN	_	Number=Sing	_	_	_	_
18	HT29	_	PROPN	_	Number=Sing	_	_	_	_
19	activates	_	VERB	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
20	transcription	_	NOUN	_	Number=Sing	_	_	_	_
21	of	_	ADP	_	_	_	_	_	_
22	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
23	long	_	ADJ	_	Degree=Pos	_	_	_	_
24	terminal	_	NOUN	_	Number=Sing	_	_	_	_
25	repeats	_	NOUN	_	Number=Plur	_	_	_	_
26	(	_	PUNCT	_	_	_	_	_	_
27	LTR	_	NOUN	_	Number=Sing	_	_	_	_
28	)	_	PUNCT	_	_	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	human	_	ADJ	_	Degree=Pos	_	_	_	_
31	immunodeficiency	_	NOUN	_	Number=Sing	_	_	_	_
32	virus	_	NOUN	_	Number=Sing	_	_	_	_
33	.	_	PUNCT	_	_	_	_	_	_

1	HIV	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	1	_	NUM	_	NumType=Card	_	_	_	_
4	LTR	_	NOUN	_	Number=Sing	_	_	_	_
5	transcription	_	NOUN	_	Number=Sing	_	_	_	_
6	is	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
7	controlled	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
8	by	_	ADP	_	_	_	_	_	_
9	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
10	complex	_	ADJ	_	Degree=Pos	_	_	_	_
11	array	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	virus	_	NOUN	_	Number=Sing	_	_	_	_
14	-	_	PUNCT	_	_	_	_	_	_
15	encoded	_	NOUN	_	Tense=Past|VerbForm=Part	_	_	_	_
16	and	_	CCONJ	_	_	_	_	_	_
17	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
18	proteins	_	NOUN	_	Number=Plur	_	_	_	_
19	.	_	PUNCT	_	_	_	_	_	_

1	Using	_	VERB	_	VerbForm=Ger	_	_	_	_
2	various	_	ADJ	_	Degree=Pos	_	_	_	_
3	constructs	_	NOUN	_	Number=Plur	_	_	_	_
4	expressing	_	VERB	_	VerbForm=Ger	_	_	_	_
5	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
6	lacZ	_	ADJ	_	Number=Sing	_	_	_	_
7	reporter	_	NOUN	_	Number=Sing	_	_	_	_
8	gene	_	NOUN	_	Number=Sing	_	_	_	_
9	under	_	ADP	_	_	_	_	_	_
10	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
11	control	_	NOUN	_	Number=Sing	_	_	_	_
12	of	_	ADP	_	_	_	_	_	_
13	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
14	intact	_	NOUN	_	Number=Sing	_	_	_	_
15	or	_	CCONJ	_	_	_	_	_	_
16	three	_	NUM	_	NumType=Card	_	_	_	_
17	deleted	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
18	forms	_	NOUN	_	Number=Plur	_	_	_	_
19	of	_	ADP	_	_	_	_	_	_
20	HIV	_	NOUN	_	Number=Sing	_	_	_	_
21	-	_	PUNCT	_	_	_	_	_	_
22	1	_	NUM	_	NumType=Card	_	_	_	_
23	LTR	_	NOUN	_	Number=Sing	_	_	_	_
24	,	_	PUNCT	_	_	_	_	_	_
25	we	_	PRON	_	Case=Nom|Number=Plur|Person=1|PronType=Prs	_	_	_	_
26	obtained	_	VERB	_	Mood=Ind|Tense=Past|VerbForm=Fin	_	_	_	_
27	evidence	_	NOUN	_	Number=Sing	_	_	_	_
28	that	_	SCONJ	_	_	_	_	_	_
29	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
30	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
31	regulatory	_	ADJ	_	Degree=Pos	_	_	_	_
32	elements	_	NOUN	_	Number=Plur	_	_	_	_
33	located	_	VERB	_	Tense=Past|VerbForm=Part	_	_	_	_
34	in	_	ADP	_	_	_	_	_	_
35	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
36	U3	_	PROPN	_	Number=Sing	_	_	_	_
37	region	_	NOUN	_	Number=Sing	_	_	_	_
38	are	_	AUX	_	Mood=Ind|Tense=Pres|VerbForm=Fin	_	_	_	_
39	involved	_	ADJ	_	Degree=Pos	_	_	_	_
40	in	_	ADP	_	_	_	_	_	_
41	cell	_	NOUN	_	Number=Sing	_	_	_	_
42	-	_	PUNCT	_	_	_	_	_	_
43	to	_	ADP	_	_	_	_	_	_
44	-	_	PUNCT	_	_	_	_	_	_
45	cell	_	NOUN	_	Number=Sing	_	_	_	_
46	activation	_	NOUN	_	Number=Sing	_	_	_	_
47	of	_	ADP	_	_	_	_	_	_
48	HIV	_	NOUN	_	Number=Sing	_	_	_	_
49	-	_	PUNCT	_	_	_	_	_	_
50	1	_	NUM	_	NumType=Card	_	_	_	_
51	LTR	_	NOUN	_	Number=Sing	_	_	_	_
52	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	contact	_	NOUN	_	Number=Sing	_	_	_	_
7	activates	_	NOUN	_	Number=Plur	_	_	_	_
8	in	_	ADP	_	_	_	_	_	_
9	vitro	_	ADJ	_	Number=Sing	_	_	_	_
10	binding	_	NOUN	_	Number=Sing	_	_	_	_
11	of	_	ADP	_	_	_	_	_	_
12	the	_	DET	_	Definite=Def|PronType=Art	_	_	_	_
13	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
14	factor	_	NOUN	_	Number=Sing	_	_	_	_
15	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
16	(	_	PUNCT	_	_	_	_	_	_
17	NF	_	PROPN	_	Number=Sing	_	_	_	_
18	-	_	PUNCT	_	_	_	_	_	_
19	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
20	)	_	PUNCT	_	_	_	_	_	_
21	p50/p65	_	NUM	_	NumType=Card	_	_	_	_
22	heterodimer	_	NOUN	_	Number=Sing	_	_	_	_
23	to	_	ADP	_	_	_	_	_	_
24	an	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
25	HIV	_	NOUN	_	Number=Sing	_	_	_	_
26	-	_	PUNCT	_	_	_	_	_	_
27	1	_	NUM	_	NumType=Card	_	_	_	_
28	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
29	oligonucleotide	_	NOUN	_	Number=Sing	_	_	_	_
30	.	_	PUNCT	_	_	_	_	_	_

1	Cell	_	NOUN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	to	_	ADP	_	_	_	_	_	_
4	-	_	PUNCT	_	_	_	_	_	_
5	cell	_	NOUN	_	Number=Sing	_	_	_	_
6	contact	_	NOUN	_	Number=Sing	_	_	_	_
7	activation	_	NOUN	_	Number=Sing	_	_	_	_
8	of	_	ADP	_	_	_	_	_	_
9	NF	_	PROPN	_	Number=Sing	_	_	_	_
10	-	_	PUNCT	_	_	_	_	_	_
11	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
12	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
13	only	_	ADV	_	_	_	_	_	_
14	partially	_	ADV	_	_	_	_	_	_
15	inhibited	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
16	by	_	ADP	_	_	_	_	_	_
17	100	_	NUM	_	NumType=Card	_	_	_	_
18	microM	_	NUM	_	Number=Sing	_	_	_	_
19	pyrrolidine	_	NOUN	_	Number=Sing	_	_	_	_
20	dithiocarbamate	_	NOUN	_	Number=Sing	_	_	_	_
21	and	_	CCONJ	_	_	_	_	_	_
22	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
23	not	_	PART	_	_	_	_	_	_
24	correlated	_	VERB	_	Tense=Past|VerbForm=Part|Voice=Pass	_	_	_	_
25	with	_	ADP	_	_	_	_	_	_
26	a	_	DET	_	Definite=Ind|PronType=Art	_	_	_	_
27	significant	_	ADJ	_	Degree=Pos	_	_	_	_
28	decrease	_	NOUN	_	Number=Sing	_	_	_	_
29	of	_	ADP	_	_	_	_	_	_
30	cellular	_	ADJ	_	Degree=Pos	_	_	_	_
31	inhibitor	_	NOUN	_	Number=Sing	_	_	_	_
32	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
33	alpha	_	NOUN	_	Number=Sing	_	_	_	_
34	.	_	PUNCT	_	_	_	_	_	_

1	NF	_	PROPN	_	Number=Sing	_	_	_	_
2	-	_	PUNCT	_	_	_	_	_	_
3	kappaB	_	NOUN	_	Number=Sing	_	_	_	_
4	nuclear	_	ADJ	_	Degree=Pos	_	_	_	_
5	activation	_	NOUN	_	Number=Sing	_	_	_	_
6	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
7	not	_	PART	_	_	_	_	_	_
8	detectable	_	ADJ	_	Degree=Pos	_	_	_	_
9	before	_	ADP	_	_	_	_	_	_
10	1	_	NUM	_	NumType=Card	_	_	_	_
11	h	_	NOUN	_	Number=Sing	_	_	_	_
12	after	_	ADP	_	_	_	_	_	_
13	cell	_	NOUN	_	Number=Sing	_	_	_	_
14	contact	_	NOUN	_	Number=Sing	_	_	_	_
15	and	_	CCONJ	_	_	_	_	_	_
16	was	_	AUX	_	Mood=Ind|Number=Sing|Person=3|Tense=Past|VerbForm=Fin	_	_	_	_
17	dependent	_	ADJ	_	Degree=Pos	_	_	_	_
18	on	_	ADP	_	_	_	_	_	_
19	protein	_	NOUN	_	Number=Sing	_	_	_	_
20	synthesis	_	NOUN	_	Number=Sing	_	_	_	_
21	.	_	PUNCT	_	_	_	_	_	_

1	Document	_	NOUN	_	Number=Sing	_	_	_	_
2	0030013199	_	NUM	_	NumType=Card	_	_	_	_
3	ends	_	NOUN	_	Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin	_	_	_	_
4	.	_	PUNCT	_	_	_	_	_	_

